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<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQK7</accession>
    <name>A0ABR1UQK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_015414</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NRDE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660613.1">
        <property type="nucleotide sequence ID" value="XM_066819728.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052788"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013633">
        <property type="entry name" value="NRDE-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471:SF0">
        <property type="entry name" value="NUCLEAR EXOSOME REGULATOR NRDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471">
        <property type="entry name" value="TETRATRICOPEPTIDE-LIKE HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="434"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="434"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8061193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="458" mass="51207" checksum="BFA6D9724032C66F" modified="2025-10-08" version="1">MSHQQISPSTEVLFPSTTAWFNYMDPAIHALTNDGQLQLVSNALKQLARSHGRSDLAVYHLAFDICSSKTDGKKAAKALLRKYPTNIELYIGYANYEFRAGNNAVASNVVTAALQLPSLSYEEKLQLSLAWAWMALEQGDLATSLSRLCLTGQETQSAITEPASPALILKNPADPDLELRGNATVASLYAKALVLLQYLTQQSGKEPRGEGQGDIEAAMAVVAKCSDEFKARGLAADAGHERLLQFAAQLLYVHISHGPYRPAFLREQTAAFLGFFPDNTIFLTLFAWKETRLGIDDRVRALLTDVVLTKPHDCASARVFAIRHEMRSGNAHSTRAAFEHALEDSPGCKHNAGMWVSYIRYCRETKELRPKAKEVFYRAIQRCPWSKEVFMEAFGTLVRDLDSAELRSVYSTLYEKGVRVHVEMDEFVGRWKEEARQRDQQRDQQSHSHRPAVGGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTK9</accession>
    <name>A0ABR1UTK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dcp1-like decapping</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660862.1">
        <property type="nucleotide sequence ID" value="XM_066818674.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051734"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13182">
        <property type="entry name" value="EVH1-like_Dcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="30684" checksum="4803032C35D42CCA" modified="2025-10-08" version="1">MSRSTPRKNRGQQQSQQPTLSHMHSHHSTTPNTNQQSHPQRSGHGHQRTRSQHLAAQAALNNQITSDYESDTASYMASHPPPSTAILAQRTNTDLNLSVLQRYLPSITQIKSQAANAVVYTFSAELNSWDKSGIEGTMFVCAQNVDATPRSSAQGFQHGAQSKGCIFVLNRRGLNNMILDLSDVEAIEASEELLIFKLNGETDEGMPRVVGLWIHADEESTRSTNTRIIQEMWDRIREMESIINAQGTASAAPGQAADDYGPAMQAIGRKVSLSDLFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTL5</accession>
    <name>A0ABR1UTL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660878.1">
        <property type="nucleotide sequence ID" value="XM_066818690.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051750"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="185" mass="20751" checksum="9AAD3D7DA6FDEC04" modified="2025-10-08" version="1">MASKSETLSILLGPLDHIAPCNIPQSIIYLGLKQQVDPQDAFVCLREGLRRTIHQAPWLNGRVYFQSPETPGWRPGQLEIRYKSPPEQESSGTPPPSHEIPLRFHELPSTTSYDELREAGFPWTGSMTKIYSGHRRSSPISGQGRKYWQHKPISFPGLPPSAVHRTASLGRDGDAQRDQDMGRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUA6</accession>
    <name>A0ABR1UUA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014604</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661106.1">
        <property type="nucleotide sequence ID" value="XM_066818918.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051978"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="306"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="442" mass="49170" checksum="DFFBECF4DE5FFF40" modified="2025-10-08" version="1">MPALNQARLTLPRSRRRWPGPVRWLSLGVLHDEIDLWFNSQDKPRIELAQTRELAIEALAEATGPDVEGDEWDVAWQPASRILCFKNRVAQEERPAGRWGSRLWFASLPGATAFYPSDNKDQAGYADDDCGPSEAQSREALAAALALGYRRPRIVSQILALGNANLDYATLDHREIANTTFVPFPAPGIQVTPLEWAVEHDRPDFARLFLDAGAYANHTVWKVEGSTLTKAVRKRNRELVEMLVPESERVTRTRALGLAAIAMALLEGDGATLCDFEEADRHLPEDKWDSDCTLGYAHISELAAGDFVVPLALAVMVGDVALVRLLLGHGADPNRGYHGLYPTAGQYEEDPDPAPYWIHLHSGRAVQLAMELGHDEIVDLLLDYSVNIDLHQPVWEEPDGEDRLRTGYSCCLMPRRVYLRVMAGLEQAVERRGEETVGPNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUQ5</accession>
    <name>A0ABR1UUQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral peroxisomal membrane peroxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014732</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661234.1">
        <property type="nucleotide sequence ID" value="XM_066819046.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052106"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006614">
        <property type="entry name" value="Peroxin/Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052646">
        <property type="entry name" value="Peroxisomal_PEX28-32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00693">
        <property type="entry name" value="DysFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Peroxin/Ferlin" evidence="7">
        <location>
            <begin position="363"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="487"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="331"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="503"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="529"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="557"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="650" mass="71550" checksum="A19B5D2C2791D6CE" modified="2025-10-08" version="1">MSTPSKPRGDGDVDGSVSSPIIENPYGAPPPTYAAFSSTNLSTTATAAARRSTILVHQKSPLLLATPPQVTRALAYSHPFLLPLNKLAGLLSWTTGDAWESFLLLVVFWATVQYGDFLVRFAGPIVVVMGIIGGMYGRRYSPLSSSGWGEHPSWASSSSSKSSKKSSAAEGSAAGGASSKKGDHQRNKSESTNTRHQKTLDEIVDTVKVFTTRCNILLEPLLLMTDFLSTQRTATSATTRPALTALFVRILAVTPVWVILTLPPLRIITTKRVIMLFGTLVLSWHSRICKVSRTLLWRSATVRRIARWVTGLEFEGPKKLTKDAVNGKTLGRSNATKKSQSTSALTTLLQRSRSGFSSGKETGVRFTFILYENQRRWVGLGWTNNLFAYERAAWTDEHNNEVPPKDEFALPEVEDGHARWRWVKGSKWRVDGVSDIQDEHDYDSEAGKNGWIYYDNKWNNGRRGADGWGRWTRRRKWYRDAELVEVNDETEISGSSTPAEPTISPPPPELPARPAPPRQDVAESKAPLSSSVQSGSSDPGHSQTSNEHDRDNEETDTASVLSTSSKSARGFKWPGFGINPYAHHSHSNPPSIRGKKVTNSSKRTRRTSDSVNSAHENDGSLTPALELEIQGSRKEQASWGFGDEVAMGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUV3</accession>
    <name>A0ABR1UUV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014777</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661279.1">
        <property type="nucleotide sequence ID" value="XM_066819091.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052151"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF78">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="564" mass="62753" checksum="5EEE9B5F4146C01A" modified="2025-10-08" version="1" fragment="single">MASLLTASWPSATHLMTLFVAGVGSHHLIRPFEIDSYPLTICSAYLASLAAAFLLYFRTVVGVDAWTAAAHTLILSCTFNAGLVSSLLIYRVFFHRLHRFPGPFAAKISRLYAARASADGLQMHLATQRLHDEYGDFVRTGPRHLSILRPAAIPAIYGPATKCVRSPWYNAHPGGLDDLSLLQTRDPEAHRRRKKLWERGLSFKALQSYEPRVRAKADLLLTRLDENVGKPIDMTMYGMFYGFDVMSEVGFSKDFNMLNSQKEHPAIVALHNSLSILSIVGGSLPWLLGMLTRIPGASAGYQEFIEWCGGELQARRKAYKQERAMNDQDPSDVVSWLIKGEEEGDVGAPRSNLAWQEEARLLIVAGSDTTSTVLTNTLYFLASNPEIYHKLQDLVDTALKADGGDSTEVTHEKIKDIAYLDWLVQETLRLKPAVPSGVTRLTPPEGLQIDEVRVPGDTIVVVPMHSIQRDARYWGNGGDAAAYRPERWEGLSTEKAAWMAFNRGAGVCPGKNLAFMELRLVLAKIAARFEVPRFAPGFDAEAFDRGAEDRFTMHLPRCCWCSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVP9</accession>
    <name>A0ABR1UVP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_015108</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661610.1">
        <property type="nucleotide sequence ID" value="XM_066819422.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052482"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF453">
        <property type="entry name" value="S1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045515728" evidence="6">
        <location>
            <begin position="23"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8063011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="471" mass="51297" checksum="49D1545D73578D9F" modified="2025-10-08" version="1">MRISTASMATGLSAMLATLAAALPGPASRLDKRYTEERNGINYNVFEHADTRSKLSFVNNSGICETTSGVNQYSGYISVGPDMNMFFEARDNPTTAPLATWFNGGPGCSSMIGLFQENGPCQFYNGSSTPSLNPYSFNNYANMLYIDQPIGVGFSYGNDTVNSTVSAAPKFGPCCNPSMRSFPSMKAVILSYGGHYGPEFATYIQQQNAGISAKNVTGEPINLVAVGINNGWFDSKMQYRAYIDYSANNSYKQILTPEGYSEYMNTYTSDCEPAINGCYSTGTGDLCSGAQDTCVQDIENAIMGEADFDPYDVRQSSNDPYPPGQYKNYLAKQSVQKAIGAQSSYQECPSAPYLKFSDTGDNTRSLLDTLSDVVQSGVTVLVWAGDADWICNYMGVQAVANAVDFDGSDEFNAKDLQPYTVNGKETGKYKTVKNFTYLQVYAAGHEVPYYQPETALQVFMQTMKKKGISST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWD3</accession>
    <name>A0ABR1UWD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPAse AAA+ type core protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660732.1">
        <property type="nucleotide sequence ID" value="XM_066818544.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051604"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="33528" checksum="35104731A40CE416" modified="2025-10-08" version="1">MADARASSIEYCALEPGDETSSAVNPSPTLLYEPLKPQIHTIIDEFQDLLINEGNVSGSGGNDPLLDDFIVAKGTSLLMVLVGHTGLDKTLANEAVAEKAQQPLYALGASDLGRRPLVAEPVLKEALGMGANWDAVLLLDERDMFLQRRCATWREQNAIIASHIMRTNCADAINHAFKSRIYLTLWHPNLSTETKSASWKHWRKIKNIVARPPSDGLVGQGAAQPGAHGEGSEHDDGRGHSVIGPGLIRGGSHLGISSNDVSSSGNQILDGQRIPRDLGSYMGCGRAPFCGVRAGQPDSLLIYTTHDDTTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWK5</accession>
    <name>A0ABR1UWK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661035.1">
        <property type="nucleotide sequence ID" value="XM_066818847.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051907"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045515727" evidence="1">
        <location>
            <begin position="22"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="74" mass="8195" checksum="BEEF72DCD9EFD94D" modified="2025-10-08" version="1">MRFFTLFAILAAVVVPAACHANETEFEIDYKVIAIGVSKIMTECGNKGRKLKKTSGEAHQKGWYVQIGHSGRHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXC4</accession>
    <name>A0ABR1UXC4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661289.1">
        <property type="nucleotide sequence ID" value="XM_066819101.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052161"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="35037" checksum="DF75207DE7E984F2" modified="2025-10-08" version="1">MLFLRTASRRPELAAYVHTIDLGCGVFDSHAATVHYKDTPALPTVGADLADLVARVEGFNVPYADRWVEELRQGRMGAFVALLLGLTPNLQHLHIDEEYLPDKYTSGVLVKACMDQTAPGSVKDHEDFDRRLLLTCDKVDLLSLLYLPAAKAWPFADGTAAPGWWPAAHQASPKDLVSLDLTMHKQYYAKRILSTMKNLKYLRWRWRGKRVHNEVTGEMVLYLHLSTVAQCVSHIHKSLTDLTITIGHVELELGHRYDTVRVRGTLSDLTRFPKLKSLEIPLIFLTTSFTPQRRRRTTLRNPCRQASKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYB0</accession>
    <name>A0ABR1UYB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661635.1">
        <property type="nucleotide sequence ID" value="XM_066819447.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052507"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8063036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="175" mass="19648" checksum="F5D59CCCED8552C3" modified="2025-10-08" version="1">MDKHERLRCGICGVVFTRSDSVASHKFSAHGQTTRHVCHMANCHRGGLGLTTHDLLVAHLRDSHQGATIADNEAALENKEVAPEAESSAVQNDDIVPDEEMEDLVHDNDGYPTKSAEEYETQIFNLQEKLEERHLEIARIHKTYKKQLEELLDKAAGKDKELEQCIKEAHDSIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYS3</accession>
    <name>A0ABR1UYS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein TmpA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661542.1">
        <property type="nucleotide sequence ID" value="XM_066819354.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052414"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN TMPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="52091" checksum="D232AA18CD0D18D8" modified="2025-10-08" version="1">MQKTRGREAGPDSLQVRGFCCMADMVVFKMEWAAVSVADVAAPSKPASPTPKPLAFIRYRILNTYRRLFSLAFLGNIAAFVVVAVRGPSPLNLLNAVSANLLASGLARTPLVVNFLFRVLCLVPHSAPLRLRHLACKIFHLGGVHSGCGVAAYLWYLGFIVYYTKDFVPSPTSTAVLVIAYAVLILLTSMILVAFPKFRIIRHDWFELIHRFSAWATIALVWALLLIVAAAEGPSMGMFLVTSPAFWMHLASTAAIIHPWLLLRRVEVVPEPLSSHAVRLHFNYDTSVEFGQGLSVSKHPLRDWHSFAVFTDRHDAPETEFSLLVSKAGDWTSSVIEDPPRHLWKRGLPAFGFAYVMKVFRRTVLVATGSGIGPCLAFAPMRVLWQTRNPERTYGRRVMELVKRLDPDAEIIDTSEGGRRDLLPIAMRLYREFNAEAVGIISNETVTKQLVYDLESQGIPAYGPVFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1K9</accession>
    <name>A0ABR1V1K9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">General alpha-glucoside permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011799</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661806.1">
        <property type="nucleotide sequence ID" value="XM_066816114.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049174"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="304" mass="33666" checksum="1B4366BACF1C3C92" modified="2025-10-08" version="1">MFQHTSSIQPIFQALEVTRPECRFDSVDVVMSHMVLTRLLLFCGVAAAPFRINASLIHDSLVLKYCPERVQPERASLGLQFEEATSSYPKGLEDSHNHWRVLRYRLGPLKRVVYYEADATTEPYACVLSVASGLGSAGDSGIPAREGSSAAVVVVRGHLTDQEHAVEIKCTERPYGRSPRNSKLWAGCVNHLLLGRLADGEIIWTRMVDVRQRVAQWSRVHDKQEALSRLPALISELKDAVRATPNGRAALVFRGVGLGEVRAEVEAEVDVYSLGQDEGCVISRAMTNKFWNASGRKKAQGRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1Q1</accession>
    <name>A0ABR1V1Q1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glyoxalase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661851.1">
        <property type="nucleotide sequence ID" value="XM_066816159.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049219"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07253">
        <property type="entry name" value="GLOD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050383">
        <property type="entry name" value="GlyoxalaseI/FosfomycinResist"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21366:SF14">
        <property type="entry name" value="GLYOXALASE DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21366">
        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="58"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="212" mass="23194" checksum="77494959F38FFF07" modified="2025-10-08" version="1">MYRTPVSLNRLLSSSHSLIVQRSSTTTILRSTTISSLSYHTHRRSMASATSSIAKVRSLDHLVLTVQNLQASVKFYESVLGMRHTTFASGEGDSQTERHALVFGSQKINLHVKGREFEPKAQKAQPGSADLCFLVDEDVEMVAARLRNQRSDIEVLEGGGVVERTGARSKLRSVYVRDPDGNLVELTNEVGDSDIGGIKDVPGMEDVPVNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2X1</accession>
    <name>A0ABR1V2X1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-alpha-acetyltransferase 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012034</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662041.1">
        <property type="nucleotide sequence ID" value="XM_066816349.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049409"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="190" mass="22350" checksum="0DAC2A94FE364311" modified="2025-10-08" version="1">MATFRRFDPSDLDRISKCNLDPLTETYGLDFYLQYYAKWPSMFQVAEDDRGNIIGYIMGKLESSPEYFRNYEHYLPWHAHITALTVAPEARRMGIGRILSEKLEIAADNGDAWFMDLFVRKSNHRAIKFYESMGYSVFRVVKDYYGENVEDPSAGGEDAYDMRKPMKRDVKHEHIRENGRDFEVEPEDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V300</accession>
    <name>A0ABR1V300_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">60S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662296.1">
        <property type="nucleotide sequence ID" value="XM_066816604.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049664"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_eL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_eL31_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="Ribosomal protein L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12829" checksum="6E09A8D8AAFA1370" modified="2025-10-08" version="1">MSSGKKTSGKGALEQVVAREYTIHLHKRLHGATFKKRAPKAIKEIKEFAHKTMGTSDVRLDPPAEQEGVGAGCQGIRVRISRRRNDEEGAKEKLYSYVQAVNVKNPKGLVTTVVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V430</accession>
    <name>A0ABR1V430_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_012669</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662675.1">
        <property type="nucleotide sequence ID" value="XM_066816983.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050043"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF13">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045319017" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="12">
        <location>
            <begin position="18"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="13">
        <location>
            <begin position="18"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8065922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="234" mass="24770" checksum="2562038FB4568C2F" modified="2025-10-08" version="1">MKLNLITTLAFGLSAQAHCIFQKVSVNGKDQGSLVGLRAPRDNNPVYDVTSNDIICQKPGSTSTQVISVAAGDKLGAWFQHVIGGAQFQGDPDNPIAKSHKGPVTAWLAKVADGAAGTAQKTGLKWFKVWEDTKNGWVEFALPTCVAPGDYLLRVEVLALHSAKTRMGAQFYTSCANLRVSGSGSFTPSSTVSFPGAYRQDDPSILVNIYGPMGQPDNGGKAYNAPGNVPVIQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4N7</accession>
    <name>A0ABR1V4N7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA polymerase II elongator complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012906</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the KTI12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662912.1">
        <property type="nucleotide sequence ID" value="XM_066817220.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050280"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013641">
        <property type="entry name" value="KTI12/PSTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12435">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08433">
        <property type="entry name" value="KTI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="38259" checksum="6895D511F6AD48A5" modified="2025-10-08" version="1">MPLIMVTGFPTSGKSTRAKQLYSYLDNRIKETSNGAAPKYRLHLISDQTLSISRSVYDLSTLPAHTRSANASEKDARATIYGAVKRVLSDKDIVILDGLNYIKGWRYQLHCESKAVRTPSCLLQIGCPTDKAKEVNQERLRKQQEAESAGQDPVQSSPEDESEAPYAPENWENLVFRYEEPNAMTRWDSPLFTLLWDDDEEQTKQTFNSLWDAIAGEGRKIVKPNQATVQRGRDAGGDYLYILDRETQDVVKRILDQQSEEGGDEIRLPKDPSQTGGDELVVELPAGKKTGLPQLQRMRRAYMNLNRGGIGLELVGNLSGSARIRDSFVRYLNDAFEREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4S0</accession>
    <name>A0ABR1V4S0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662946.1">
        <property type="nucleotide sequence ID" value="XM_066817254.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050314"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="3">
        <location>
            <begin position="34"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="302" mass="32598" checksum="D3FCF56E25A15BA7" modified="2025-10-08" version="1">MSSFMESLPRPTKTYHTKSYARLAQHHGFEGAGKTVLVTGGASGIGLAISKAFAEAGASRLVLVSRSAAPQAQAKAELEAAHPGLEVVTYAASIADRARTAEILRDLESGGGVDVLVLCAAVAHRRVTAAEVAPLEVRDAFEINAVAAFDWAQTYLASPVPKSRSKTLINVSSAVAQMRHPMRAAYGPSKAGAAQIMQAFAAEVDWKQKMQPQGEEGKKTRIFSFHPGSLYTAGTAEHFAQDALEWDDMELPAHFARWLAGPQSDFLHGRFLWAHWDVDELVAAKERLRENPEALTIGLIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V545</accession>
    <name>A0ABR1V545_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663078.1">
        <property type="nucleotide sequence ID" value="XM_066817386.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050446"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451">
        <property type="entry name" value="MARVEL DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF3">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="32296" checksum="2335AC8D2BFBDA8D" modified="2025-10-08" version="1">MAIFESLEWDADYVPGVKLGLHSMQVLFGFVIFVLEIILFKDDKALINGNNGWPFGLCFLSVLAWIYLVMTPRWERSRKLAQPHAMAVVDGVFAIFWLSAFASQAAYNTANSCGNQCKVSKAVVGIAFFEVLFWIGTTLVSLYTVQYYNFNGNLPGYDKVGKRTQNIDPDKAAFSMAPHDEEAYAPVNMDDHDGDHLGNSHTPYNADSYGSRPMFDSETEYRPHTASTGAPQLDNPFADNGRLTPLNDPYASSYGGSDAGGPRLYAPPSVSDFDDVTRPAQFPAANYDRTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V551</accession>
    <name>A0ABR1V551_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663065.1">
        <property type="nucleotide sequence ID" value="XM_066817373.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050433"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF3">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="560"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="686" mass="76263" checksum="3BD5DC272B35EFA6" modified="2025-10-08" version="1">MSIHDWKRTSIDAPEGSASQYDPPPAYSSHLSRGDPRSNSTQSLVPSLPNYDEVSKRRLLVVYIHGFMGTDHSFQSFPAHVHRYLRDALIDSHVVHSKIYPRYKTYKAIEVARDNFSRWLQPHESPTTDVVLVGHSMGGLLAADVALMQSWDQNSPNFFQNRILGTVNLDAPLLGLHPGIIVAGLSSLFRSKTDTPKPAGGSTQGTSSVTSPEPSLNSDFASPTPTSPLSDPPTSVPDLPARMTMDPNFDPEFPNDVRLKDRSWWKNIVHFVKKHNSEGIIDAASHHIMSHLEFGSVLMDFNCLKIRYENLRKLEDIDDMKNHGFPHVPPQVRFVQYYTVCHGHPKKPKGSKEMDAADRKEIENAMASGPSATSSTTSTPRASIGDIYDEGRKRSSMRSLPDIPKENAAGPSRDGDNQRLGGVDADPEVDAAAKELSELELSLPKVPDPPEKPEPFDGTKYTDKDARKQAEKESKRVVKAYEQAVKNREKTIKERQKVIDKQQRKKDEQAAHETEKRGEEAEREAKEQRQRNEEAIQILADGIEERQTSLADTAAAVAPKPSAAAATEANVDRSISQASTAEGEGSLSRVSSNESDSPKATKDQKKAAKPPKPKKERKFCTLPSKVKGQLDPKWIKVFMKDMDEVEAHTSLFFPGPHYDKLVGDMGDMIISWVQEDATKRAIWEMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5H1</accession>
    <name>A0ABR1V5H1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663205.1">
        <property type="nucleotide sequence ID" value="XM_066817513.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050573"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047289964" evidence="2">
        <location>
            <begin position="19"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="140" mass="15265" checksum="7F191BE442B58AD1" modified="2025-10-08" version="1">MKILQSFTFAYLCGYATAAAIITARTTTGAPDLDKVCDECTVCLNNAAASVDIGAVTTCWDQLCEACAEGPEQGPEQDGQGIDSQSWSSTEDDDDKVCDDCFACLYDADDNEDAEGVCFEKYCNTCKEKHKDDDDYRDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5V3</accession>
    <name>A0ABR1V5V3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-specific glutamate dehydrogenase</fullName>
            <ecNumber evidence="4">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013317</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663323.1">
        <property type="nucleotide sequence ID" value="XM_066817631.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050691"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056365">
        <property type="entry name" value="NAD-GDH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016210">
        <property type="entry name" value="NAD-GDH_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055480">
        <property type="entry name" value="NAD-GDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF24">
        <property type="entry name" value="NAD-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23147">
        <property type="entry name" value="GDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23152">
        <property type="entry name" value="GDH_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000184">
        <property type="entry name" value="GDH_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="707"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="13"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1071" mass="120158" checksum="9DC358B1EAD1A3A6" modified="2025-10-08" version="1">MLSLQTADLPLDRFPEYAESPDASRSPSMSVNGPINKLVQQLQGGAEPSRTPSPQPTHFSVPQTNGNGHRVLRSATVGYIAPEFKGKAEQKQSVKEILFKEAWIPERLVDAQIEWFYSSLGIDDVYFQLESPEVIATHITSLYAAKVAAHNHPNKQEEIRLDMEASDHAIYIDTSEPGQTATSGPRYEQRLEAKYLDHVGTKRFRVETFRSPGTLSESPDSKASLRCYFVYQCQFVDSNPPPDETRLEVIADRMFMTKATKNTKFIYQDIITLAVNRTGPVIEVFDIEDSPEKRLVVAFRSRTARGMFSALSDLYHYYGVTSTRKYVEQFSNGITVMTRAYHGYRVGSTPLEQSIHQITKEISLLYCIPQNKLHDLFAHGELSLQEAIYGHCVWVFVQHFLNRLGSEYVSLTQALDPKNNVHAGILSKLKRRLRSETFTPDYILEIITAYPALVRTLYAQFASVHLSAGAGFEKHFVAPTPAVEVLSDARMKEKISREVANEHDEMVMTAFRIFNNAILKTNYYTPTKVALSFRLDPAFLPEIEYPKRLYGMFLVISGESRGFHLRFRDVARGGIRIVKSRSKEAYAINARNLFDENYGLASTQQRKNKDIPEGGSKGVILLDPKQQDKAQEAFEKYIDSILDLLLPAKTPGIKNPIVDLYRKEEIIFMGPDENTADLVNWATEHARARGAPWWKSFFTGKSPKLGGIPHDHYGMTTLSVREYVKGIYRKKNLDPATVKKMQTGGPDGDLGSNEILLSNESYTSIVDGSGVLVDPNGIDKEELIRLAKKRAMIGEFDVSKLSKDGYRVLCEDSNLTLPTGEVISNGTAFRNTYHLRESGLTDCFVPCGGRPESIDLVSVGKLIKDGKSTIPYIVEGANLFITQDAKLALEDAGCILFKDASANKGGVTSSSLEVLASLSFDDEGFVTHMCHNARGEAPEFYKAYVKSVQDTICNNAHLEFEAIWREHEQTGTARSILSDKLSEAITKLDEELQKSDLWENEKIRRSVLADALPKLLLEQIGLDTIIERVPNAYLRAIFGSYLASRFVYEFGASPSQFAFYDFMAKRMAKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7F9</accession>
    <name>A0ABR1V7F9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013624</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663630.1">
        <property type="nucleotide sequence ID" value="XM_066817938.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050998"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045359745" description="Peptidase A1 domain-containing protein" evidence="3">
        <location>
            <begin position="34"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="532"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="660" mass="69555" checksum="BE587B814225D76B" modified="2025-10-08" version="1">MKAVIAGQQFRVSVTMTLLSVFLLLAAVPPAHAVPRAARWSTKSLGPDGPWNALEITMGKGQTITTYAGKMWESFFLDSDYCNATTKANSKRASGKQQQPCYAKQAGAIYNEGASSGTGSAPSAVSPNPGTYFSGAMDSVAGAKTNGPDRYRDEFHLSRNTKEWAAGDTVANLDMVLLSETQLKYPGGDLVPLFAGCLGLGAAPGIVNHTYRAQSGSGDVNMSMVAGAYAKQGFTDTNSFGMHIGSALPSSPLTPKKKMMEGSLWFGGYDKNRVIGEVLAIPIPQPYLIFDGLPLLDISINVIKGGSPFGPNGDQGNGWRSKSGYLASGNTTMAPPLNIRLDGCHPYLNLPKSTCDALAADLPLTYRPALGLYVWDTASPSYPRIVSSASALTFTFLDPDNNAHRVNPTPYFPCNAGSAGAHYTLGRAFLQDAFFAASFDSGTYFIAQAPGPNIVSVDAANANTAVIGKTARTLAASNNDWRTSWEGLWTPLPGGDGEEESDPTTKSSGDTKDGGGDENVDEKGGGTVTRNAGVIVALAVGIGGGVSLLALAAFVLCRRNKYGTGSTCCGWRIVKAKEHATGGSGAAVPGSKGIQPKHEQQQKDEEQEHPEHFRHELPLNEAPSQLPDNQVSRRPISGVTAAAPGGDVQGNRRRKDRCLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7J0</accession>
    <name>A0ABR1V7J0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663660.1">
        <property type="nucleotide sequence ID" value="XM_066817968.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051028"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047525060" evidence="2">
        <location>
            <begin position="21"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="439" mass="45158" checksum="399CCAE1CBDC963F" modified="2025-10-08" version="1">MKSSTIVTVASACLLQTAAATSAPKGCCRSNQCLKAIGSPLNNGVADCSANLVVTVTVAPSSAVTTTETATQTGVDTALFTETVTETAATETLLFTTDATVTAATQTNTVDETVTVLVTSTDLQTAPTPTTTTLVYSKDDPTIFRKKRLATVTSLAGSVVSALPDYVSAVCPSWDKYTSACRCAGVEPVTVTVAAGAAPTVTETVSTSVVGSTLSRTDVETAPATATTEATRTETVTETPTPSTATEVTTATSTTVAQATATPSAVVVPQNCRPTGPWFRGQTYSLSTQSEGPKYMYTVDTSSDSSSISWAQFSTIPSGPEYQSQQWVLDDQGQLQQFNPAAGASEVQVAYVDGGLAQGPADTVPVAMMKLNGAQFLTFIGAIARVQGCVSPGTNALTLRDMIGARSNILQCGTAMVLSRGDGSDFYPGGCTPVTMEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7L0</accession>
    <name>A0ABR1V7L0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_013053</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663059.1">
        <property type="nucleotide sequence ID" value="XM_066817367.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050427"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740:SF2">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="87"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="294"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="11">
        <location>
            <begin position="395"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="270"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8066306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="567" mass="63329" checksum="E9A2AA63592EEA2F" modified="2025-10-08" version="1">MGVPAHDLRDFNFWSAHQPGQPIKFAVTPNEDGQTSGMEDGPFLNAGYMTSLAGAHKGLPSGKAAEAVVESIQASTGSAKGVVKWKLRDWLISRQRYWGTPIPIVHCDTCGPQPVPDEQLPVTLPEVEHHWKEGRSGNPLESATDWINTTCPKCYGAAKRDTDTMDTFVDSSWYYMRFADPQNGELPVSEAALKEHLPVDIYIGGVEHAILHLLYARFIYKTVVDLLYSEKLGQEDGQSILEPFTRLITQGMVHGKTYTDPTSGRFLKPDEVDLSNPSEPSVVTTGEKPGVSYEKMSKSKHNGVDPTDFISKYGADATRAHMLFQAPVSDVVNWDEDKIAGVTRWLRRLYDYVQSLGAVPEENSEWAAKEYFTKIKKELGEAGQEQAAQWSADTDVWRATQQTIDQITKSYEKVYSLNTTVSLLMGLTNTLADSKAVSQTVKIAAMNHLLRMMAPITPGFAEECWRSLYPSTNSIFDSTWPEPDGTIELLGHNYIKCAVMVNGKMRYVATVPHRPSNMEEKSQEYQNWLTDRILQTEEAQAKLSNFDIRKAKKAFVVKGGKTVNYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7W9</accession>
    <name>A0ABR1V7W9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014036</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664042.1">
        <property type="nucleotide sequence ID" value="XM_066818350.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051410"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8067289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="78" mass="8418" checksum="B5B45726794F1346" modified="2025-10-08" version="1">MGERVGDSWGPQIAPFCIGMAFPVFATNRGHSNSRTPEAATRREFAERVAGSWPMCCVRTGGTERTDLMKAPVMTGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7X4</accession>
    <name>A0ABR1V7X4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013112</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663118.1">
        <property type="nucleotide sequence ID" value="XM_066817426.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050486"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024512">
        <property type="entry name" value="Ser_palmitoyltrfase_ssu-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11779">
        <property type="entry name" value="SPT_ssu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="116" mass="13053" checksum="2E4D6D8E15E5AA4E" modified="2025-10-08" version="1">MEMAQSVARWFRLKQYQIEVTFGVYIFTPIEKFVFWSVVFLLFSLTFIATVLYLPQHMVFLYNRAWFYVHGDDNSGVDGVLGGLAKGALQKTVEALSSTSSADGAGETLDSIVREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V805</accession>
    <name>A0ABR1V805_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Translocon-associated protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_013804</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Is probably involved in a pathway contributing to genomic integrity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IRC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663810.1">
        <property type="nucleotide sequence ID" value="XM_066818118.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051178"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005595">
        <property type="entry name" value="TRAP_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924:SF0">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03896">
        <property type="entry name" value="TRAP_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045043993" description="Translocon-associated protein subunit alpha" evidence="11">
        <location>
            <begin position="24"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="219"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8067057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="28521" checksum="06A465EF34188AF7" modified="2025-10-08" version="1">MVALQYSLLAALALRVVSVFAQAESPLDAGAGSPPAAELKADVVATFPEADIFGVKLVNGRPTKAVVDITNNEPEPIQVAFLGGALYTLQELPEGSHPSAGILRNLSSVRYEATIPAGEKQSLPYSFALDMNPQDVRLNLMAVIMNDANQIFQVPVADQTVSIVEAPTSIFDPQIIFLYMFLTAAFAGTCYFVYNTWFAAFFPQTKKPRAPKAVAVVEKEPLSGGEGSASGTDKTYDESWIPLDHINRPTARRVKSGASKKKLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHI4</accession>
    <name>A0ABR1VHI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010899</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664504.1">
        <property type="nucleotide sequence ID" value="XM_066815214.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048274"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="212" mass="24167" checksum="91233CFDECA730FF" modified="2025-10-08" version="1">MAFLESDKDVALWPKPDWLMEHWPSQTISHITLRLAQALGYMAGRAPISDEVLETYEWNSKAPFQVPVNVVLNDEYRGDCIMTGLNSPSENNGPPHINEGRGLQHWNARSYIVHQNGDMGAVIGIEDSERTPGSIDICELQALMILLDRQTVYHPEKAKLRAWVVSVKPDYLRALEAYVDQSVDRYTFHFSIVGETTWEERVTRNLESTDPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VID1</accession>
    <name>A0ABR1VID1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664450.1">
        <property type="nucleotide sequence ID" value="XM_066815160.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048220"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="54"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="509"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="553" mass="61348" checksum="99FCEE11C8F05D71" modified="2025-10-08" version="1">MDTTSLHTVSPASYNYQLLKPNEIRLALLEPSPHDNGPLSVRLVPTDIEAPPPYDAISYVWGDDAADTVPILCDGLFVRVTKNLHWTLSRAQRRHHHPDSSAYVVVWADALCINQHDDVERGAQVALMGRIYTNARTVLVCMGPELSYAGGSLVASLLSEWDASAATAGVDIKVDDVHWRALGALTRAPWFSRVWVLQEVGLARDPRVIYGGGPDDNIGIEEFSYRLLRCVVSWARSRMSSFAAYMKIEGLLVHDWWLDWSQPRPGGEAPGEVLHYQFLDLLDQGALLQCRDPRDRVYAFLGHPVAAAAGTIVPDYTKPKIQVFQETTLVLLRDSGIRTLSSVEHDTQTIEEDTPSWVVRWDVTPTFNNIWNSYGPTYSSAAGLGTGGALELNGDCLQVEGVVVDSVLAVFPVRLAPSTMGIWFFSANTDSWHPLVSFSPELEQDTTAPFAYNATKSAILAHTLCGRPWDDQDQDAIILRMFSDYITGGCERHNTKKRHRRRSICKQRPSAMAAPSSSPKTATTAWRREFAGQATHVPLCRAGPYRSSFGRYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VM94</accession>
    <name>A0ABR1VM94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665229.1">
        <property type="nucleotide sequence ID" value="XM_066815939.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048999"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045398523" evidence="1">
        <location>
            <begin position="26"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="181" mass="18520" checksum="973D1524C67200C4" modified="2025-10-08" version="1">MLSTATPWVQIHVILLLLILPLIQGSPITSQFLTQPATTTISSPSSFPTAASPSLRPAITATPTIAASSSASNSTRTRFSPSSAVTAAPLIHPSLQSGGGSAGLLLPSANGTYNNNINLKFVQTTYWSCVQWPTTMHCGWHKPILDASNGGGSPGRGQQGPQRAVGAGVVAGLVGFFLAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU90</accession>
    <name>A0ABR1VU90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009479</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665756.1">
        <property type="nucleotide sequence ID" value="XM_066813794.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046854"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="15"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8074816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="175" mass="18922" checksum="29A207F8E6568306" modified="2025-10-08" version="1">MAPTQLPASGNPMVFFDITLGGEPLGRITFELFKDVVPRTAENFRQFCTGESKNPMGKPQGYKGSKFHRIGGDFLKGDGTGSTCIYGTKSFADENFSLKHEQPGLLSMANAGPNTNGSQFFITTVPTPFLDGKHTVFGKVLDGMDVVKKMEATKTGYRGKDVPNLDVVIAQCGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUF7</accession>
    <name>A0ABR1VUF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_009515</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PGA52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665792.1">
        <property type="nucleotide sequence ID" value="XM_066813830.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046890"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018805">
        <property type="entry name" value="YJL171C/Tos1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018807">
        <property type="entry name" value="YJL171C/Tos1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737:SF2">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10287">
        <property type="entry name" value="YJL171C_Tos1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10290">
        <property type="entry name" value="YJL171C_Tos1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047128438" description="glucan endo-1,3-beta-D-glucosidase" evidence="9">
        <location>
            <begin position="18"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 N-terminal" evidence="11">
        <location>
            <begin position="37"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 C-terminal" evidence="10">
        <location>
            <begin position="212"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="109"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8074852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="455" mass="47984" checksum="36B641E920667235" modified="2025-10-08" version="1">MKYSMVFAAAAATAVSAGNTGKCDNEGGNFFCTAVKALQYVGLDVAGQYKEVTSMGSDGSCQFADVPFSGPIAPFDEDLSIHLRGPATIEKVAVYTPKANSKRDAPVPHSKRHGHQHLHKRFHEHSHEERAVGDVVHAKIDGQDVSWTNTYDGKGAASPQPAAPAAPAAKAPDVNVASSFVKSEKVASAPKAADSYPATSPKKTDTSNVPAGDYARVGYYDALSGEATGITFLGNYGGSGSGSGVWDTTWGNSLSYLNADGTGGAPSPTVLKGGQIPDAAEIAIFSDKPCTDKTANCGYYRPGTVAYEGFKGADKVFTFKVTMPSNGKKGWNEDMPAIWLLNGKIPRTGQYHDCSCWKSGCGEFDLIETLASGDTKCKSTFHYTNSIGNSDYLQRPTLGYVNYAVIFSKAHASASIKILADDFNHDVGLTSDQVEAMIVDDAKTPGGVSKMAIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW91</accession>
    <name>A0ABR1VW91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HAD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666448.1">
        <property type="nucleotide sequence ID" value="XM_066814486.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047546"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006353">
        <property type="entry name" value="HAD-SF_hydro_IIA_CECR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01456">
        <property type="entry name" value="CECR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF51">
        <property type="entry name" value="HYPOTHETICAL HAD-SUPERFAMILY HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="52181" checksum="22C4F273D834E827" modified="2025-10-08" version="1">MSADQGNEVNVTAPPAEGQEAQANGHHASIAIPGEHKGDGAIEIPATRSSISEAQKYMHNLSMSPSMKDRRGSRNSFGTSLPIPRSKRQSRLSSVHYPSDGADGRPARPGMPPIQPTRALLAAQVQTIEAEKVKKAKNMAFAFDIDGVLVHGDRLIPEGKHPHIFLTNGSGKPEKARCEQLSKILKNPVNTEQFIQSHTPMSALAEYYSTVLVVGGEGYKCREVAEQYGFKDIVVPNDIVAWDPTIAPYRVFTEEERATSRPRDFSKVNIEAIMVFSDSRDYATDMQIIMDLLRSENGRLGTMAKDPIAQRIPIYFSQGDMLCPTEYWTPGTFRIGFEAMYRAVTGVDLERVVYGKPELATYKYADEVITSWMEHLHGEEKLPENVYMVGDNPASDIIGGNMYGWNTCLVRTGVFQGGDNDENNPANFGVFPNVLEAVKTALRKQLGDDFKMEFDETINPTQGEKDDAAAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWI3</accession>
    <name>A0ABR1VWI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nucleobase:cation symporter-2- NCS2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010279</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666556.1">
        <property type="nucleotide sequence ID" value="XM_066814594.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047654"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810:SF2">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="530"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="564"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="614" mass="65038" checksum="FC5AA8D928C83735" modified="2025-10-08" version="1">MDEDQGPSHIAPPPEPARPSRKTVRDRLLGVRRTFCTRDGLLGQYDYGFLFTPNLPFMNRPKQVSPFFGLNDRMPVFLALVLGLQHSLAMLAGIITPPLLLTGATGVNLPGEIQQYIVSTALIVSGILSLVQITRFRILGTPYYLGTGLISVVGISFSIIPVAQGAFAQMYANGFCPTAADGTKLPCPDGYGALLGTAAVCALIEILIAFIPPKIMLRIFPPIVTGPTVMLIGISLIESAFKNWAGGSGPCADAQPTDFFKLCPDITAPHALPWGSAEYLGLGFSVFLTIILCERFGAPIMKSTAVIIGLLVGSIIAAACGYFDRSGIDSAPAASFIWVHTFKLSVYGPLVLPIMAVFIICACEAIGDITATCDVSRLEVEGKLYESRIQGGVLADGLNGVLAALMTITPMSTFAQNNGVIALTRCANRTAGYCCCGFLIIMGVFAKFAASLVAIPSAVLGGMTSFLFCAVAVSGIAIITKGVPFNRRNRFILTAALAGGYGATLVPTYFSHVFTYADDNKGLQGFLDAIVLVMETGFAVTAFVACVLNLTLPPEFEEPIEDVAPLREETDMTTTTGPLDNGGAHKGMRQNSQSMEGSSSAAAEEGYEKREKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWM7</accession>
    <name>A0ABR1VWM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Bacteriorhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_010301</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666578.1">
        <property type="nucleotide sequence ID" value="XM_066814616.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047676"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15239">
        <property type="entry name" value="7tm_YRO2_fungal-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018229">
        <property type="entry name" value="Rhodopsin_retinal_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043476">
        <property type="entry name" value="Yro2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF1">
        <property type="entry name" value="30 KDA HEAT SHOCK PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00950">
        <property type="entry name" value="BACTERIAL_OPSIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="159"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="266"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="287"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8075638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="33190" checksum="31EB6970EF53E06A" modified="2025-10-08" version="1">MGNNALATNSVIGQRANLEITTHGSDWYFTVCAIMGFSTLAFMGMAMTKPQGHRIFHYLTAAITATACISYFCMGSNLGQVPIQAEFVRPFRRQVASAGTREIFYVRYIDWFITTPLLLTDLLLTAGIPWPTLIAVIFADIAMIVTGLVGALTQTRYKWGFWTFGMFGLFYIIYELVGPARRHASALGEGPSKTFLMCGVLLSFLWFLYPIAWGLSEGGNVIHPDSEAVFYGILDVIAKPVWGALLLWGHRNITPQQLGLHIHDNTSSSAASEKGRGPHGAHGGAPDGPATTAGANGTPATAGAGGATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWN6</accession>
    <name>A0ABR1VWN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666587.1">
        <property type="nucleotide sequence ID" value="XM_066814625.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047685"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="25210" checksum="B24E8281D4E6D14B" modified="2025-10-08" version="1">MEGNEILHEIDPDGDIKLILRNPNAPFAVWDEDSSDLEIFNSSAVSAEPAVDENDKQENAIRFRLSTKHLDIIRGGEKEGNVSTIEASGWDPDALLILMEIIHGRHRGVPRRPGLEKIAKIAVLVDYYGCHEVVECSAERWTELLKDTRPKQYGRDLVLWLAICYVFYRPNIFWNLTRVAIKDSRGPIQTLKLSYHSRRQDALNQTITRLHGITIYFDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWT4</accession>
    <name>A0ABR1VWT4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription factor IIA subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009429</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIA subunit 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665706.1">
        <property type="nucleotide sequence ID" value="XM_066813744.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046804"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07976">
        <property type="entry name" value="TFIIA_alpha_beta_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004855">
        <property type="entry name" value="TFIIA_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12694">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12694:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03153">
        <property type="entry name" value="TFIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01371">
        <property type="entry name" value="TFIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="272"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="273"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="291"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8074766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="366" mass="39973" checksum="059B8DFEEC09B741" modified="2025-10-08" version="1">MSNSAVGNVYQQIILDVIEASRVDLEENGVDESILDELKQGWQRKLTAQQLAIFPWDPKPDPQLLLRHLRPLQPTMEGTQQQQQQQQQPSANNMPYSPAANNSVAGDAHIKAEPGVKIEPGTEQAGANHQTQAAPNDVVHQRLANNLRNQFGERAADTIKNLQAGEVRQGGAPQHPGQQRPMGQPATQAQQANAQAQYRGTERAGTVPPQMDGAAEEQPYSGVLMQRGADGETTELGRVEIDRMLHAAIEAKAKSMEGGGLMLPLKRATKKLASSQQISSAGSGPSRFDGGDDEEDDDEAINSDLDDSDDNGDEEDDDEDGGQIMLCMYDKVQRVKNKWKCVLKDGVLSVNGKDYVFHKATGEYEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXD1</accession>
    <name>A0ABR1VXD1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_009473</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665750.1">
        <property type="nucleotide sequence ID" value="XM_066813788.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046848"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16652">
        <property type="entry name" value="dRING_Rmd5p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037683">
        <property type="entry name" value="Rmd5_dRing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF3">
        <property type="entry name" value="GH10162P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CTLH" evidence="9">
        <location>
            <begin position="194"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="RING-Gid-type" evidence="10">
        <location>
            <begin position="385"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="7">
        <location>
            <begin position="385"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="139"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8074810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="440" mass="48450" checksum="3FC16AE8F02AE265" modified="2025-10-08" version="1">MAMLQLEKELEKLTKSARLSDAVDDVDKIIDLLTEARQRVAESANDPHTTILTLTKLQNPIREGLETVNDDLKGVHKGQNKFGKALQQAFTNDKVIKGTLPTEHDPMAAHPDLINRAIAMHLLREGQFGVASTFISEAQPQEDNSMAQFQSQLSPATLASPTSPRSPTPTDVPIVDSDPSSELSALHSEALQASFASMYSILSSLKAHDLLPAITWARGNCAELEARGSNLEFELCRLQFIWLFKGPGVNGMPDTPANGRSGALEYARDNFGRFQHRHLREIQQLSCAMVYSANMEASPYRAIFDITLAFDEVAASFTREFCSLLGLSAESPLYVAATAGSIALPQLMKFLNKVKGKGTEWTTDQELAFETPLPKSMVYHSIFVCPVSKEQTTDANPPMMLPCGHVLARESLQRLCKNNKCKCPYCPSEGRLQDAREIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY35</accession>
    <name>A0ABR1VY35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009924</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666201.1">
        <property type="nucleotide sequence ID" value="XM_066814239.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047299"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12324">
        <property type="entry name" value="RRM_RBM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008111">
        <property type="entry name" value="RNA-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033744">
        <property type="entry name" value="RRM_RBM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45894">
        <property type="entry name" value="RNA-BINDING PROTEIN 8A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01738">
        <property type="entry name" value="RNABINDINGM8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="45"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="127"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="174" mass="18599" checksum="7659EE6EA6EBF1F7" modified="2025-10-08" version="1">MADVEMDIDDAGAVGGGSPPPTAEAKVGDMQTHSKATAVRSIEGWIIMVTNVHEEADEEAVHDKFGDYGEIKNLHLNLDRRSGYVKGYALIEYTTLQEARAAIDGCHQTKLLDQTIYVDFAFVRPPPGKAGARGGRQSHRGRGRSRSRSPDQGKGEEAPAPAAADGGEDQPAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZ40</accession>
    <name>A0ABR1VZ40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666546.1">
        <property type="nucleotide sequence ID" value="XM_066814584.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047644"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="166" mass="19048" checksum="E6E1DCC53ADBEC1E" modified="2025-10-08" version="1">MSMFDEIANDSSAGQTCLSTDSHELAIRNYVLHYFGCLKFAARDRFFDPMNPRWHLYSGLWDVSSANQGEAEQDPDAYRRSWESICLAELEFVARLRNTLAEDSEERHLVDHLIASRAECLPSLRENARNRGVGSFAFSNEPENNYQQNNRPTPVEAFVEASLMFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZ89</accession>
    <name>A0ABR1VZ89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CDP-alcohol phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009907</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666184.1">
        <property type="nucleotide sequence ID" value="XM_066814222.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047282"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014472">
        <property type="entry name" value="CHOPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414:SF77">
        <property type="entry name" value="CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414">
        <property type="entry name" value="ETHANOLAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015665">
        <property type="entry name" value="CHOPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="427" mass="47699" checksum="56652837264098DB" modified="2025-10-08" version="1">MAPNKNSRTAAAECISDDALIHLKSYKYSAVDLSPVSHYILRPYWNAVVELLPLWLAPNMVTLIGFFFILANIGLLVIFIPDLVGPGPGWIYLSFAFGLFMYQTMDNIDGKQARRTGTSSGLGELFDHGIDSLNCTLASLLETGAMALGTSKSGVFTALCPCLPMFFSTWETYHTHTLYLGVINGPTEGLLIACAVMALSGIYGPDIWTTPFIELLGPKFLLGYDQLVGEYSIRDIWILLIVGSLVTSQIPFCVYNVVKARRANNLPVAPVFLEWTPMAIYTLSIGTWLYSPYSTLREENHLVLFCLTMSFVFGRMTTKMILAHLTRQPFPYWTIMLWPLVGGAVLGNLPRFGFAQISADHEYYYLCAYFVFACVVYFRWAFLVVNAICDFLGINALTIPHEKQLENKRKMEQEQQAAAAANGKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7M5</accession>
    <name>A0ABR1W7M5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666958.1">
        <property type="nucleotide sequence ID" value="XM_066811616.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044676"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052998">
        <property type="entry name" value="Hetero-Diels-Alderase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060:SF1">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="33379" checksum="2206D6F7E07D5049" modified="2025-10-08" version="1">MCASASIVKSVYGFPVEFVENLQTLSNGNLLLSTMESPTGLLYTLDPKAATPQARLVTAFDRKVTALTGLSSLPGRPGEELYAVSGGLHTSFAFEKGSMAVHIVSVTDGKVVDSIPVPDTATMNGMAALPHHPHILLSADSIDGRILSIDTQKRQAGVLLKHDMLGAGAVNNDTSSYPVPPIGINGLRVRGDYLYFTNSNQGTFVRVRIDEYGRRRGDFEVLARSPDAAHIYDDFTFDQAGNAYIATHSSSVFKVTPRGVQTLLVGDSSQYANLLTEPTSATLALDGKSIYVSTGGDFTSSPRKGGQILQIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7T9</accession>
    <name>A0ABR1W7T9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007365</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667022.1">
        <property type="nucleotide sequence ID" value="XM_066811680.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044740"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF31">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046184485" description="SGNH hydrolase-type esterase domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="3">
        <location>
            <begin position="46"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="395" mass="40068" checksum="45F1E7BA7ABF514C" modified="2025-10-08" version="1">MLLGSLLIAAHALVASADSTSDSHYLDFSRITYKRADAVPLRIMPVGASVTFGVGSTTGDSYRKDLLDLLKAQGMTAEMVGSKQNGKDFANNQVEATSGFVIAQIAKSVKSAAPKFKPNLVLLDAGTNNCNKGGDVPDAGKQVAAMIDDIYTSSPGATVVLATVLANKDAAQDKCRVGVNAQYQTLAADMAAKKAKFVLVDMRSPEGPTTADLNDSRHPNDAGYAKMAAVWLKGIQEAQTKGFLTAPVAAETSSGSGASDAKHNKGGNQQGAAKNATEPATGGGKKKGGQQQGGAKNATQPATGGGSGAKNPSKGGQKGQQPAKNATQPATGNTPKGGQKGAGGQKQNSTKGATPTNKTAGAKPTGPVKAGSSMAYEVHTLITAGMIGTALYFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7V3</accession>
    <name>A0ABR1W7V3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_007380</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667037.1">
        <property type="nucleotide sequence ID" value="XM_066811695.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044755"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="9">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="231"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8079562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="273" mass="31236" checksum="5EE02048D5448712" modified="2025-10-08" version="1">MKGYFSVQWAYWLQQLIVVNIEASRKDYWEMVIHHVITTSLIAGSYAYHLTRVGHLILVLMDAVELVFPLAKCLKYIGFTTVCDVIFGVFMVTWALTRHLFYLMVTWSFYRDVPRIVTVPCYKGTANDLQGPFPVPEQGWSHLLEPFYDPEGTVCLTKGIHTGFLTFLIALELVICVWSYLIVRVAARVLKGSSAEDVRSDDEEEVEVEVKQSEFKEVGLIEKEVGVESVDLTTRRRPNGRQPKAGLPLSRSSDRRDSRKELLNRIGCDKQIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W864</accession>
    <name>A0ABR1W864_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667148.1">
        <property type="nucleotide sequence ID" value="XM_066811806.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044866"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="59" mass="6523" checksum="77BF8EAE827AD9A2" modified="2025-10-08" version="1">MEDEVKIPREEAIKPTIDLIGNVGRHGVGQFIQRAVLRHAVVLPISLRGRKPRGATRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8X2</accession>
    <name>A0ABR1W8X2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667425.1">
        <property type="nucleotide sequence ID" value="XM_066812083.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045143"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="197" mass="20947" checksum="D849C6A85916B5A9" modified="2025-10-08" version="1">MNANGWPSGWASQNNQPYSHYQTCEDWSSPTAAYTNADTPEDVHASDPAGGILTNSQALEEGTQQHVCTHPCGEQSCVHHSQNSAHEQASSQSFAYAAHGNVSPAHPDVGVHAPASFGGGGQTGDDGSGQFLSQADGDERRRPRSVPPSVGCYIQDRQSHEELACGLGPSDVRQSTARRQRKITLAISNQDLNVQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9N9</accession>
    <name>A0ABR1W9N9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008032</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667689.1">
        <property type="nucleotide sequence ID" value="XM_066812347.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045407"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045162524" description="Chromo domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="588"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="638"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="699" mass="76259" checksum="9ED6CAEF2CE7D3A0" modified="2025-10-08" version="1">MSASLWRCCLHFGCYVSTAATSSASIRDEEGPFLVSSTEDHAAALASDVGRTTARHFHSSPLFRRGHVSTAANCVTSDERMFYSRLIPRQRSADNASLRRRDCLGFGCRVSTAATLSASILDGEGPDLLSSPEDYKAALDSEEEYFVFIFTNHSTNLALIGQERLAEPGSDTTQTPVIHGDFQNHQPVNFEDEIPSTLLLSKSRSRWILPQAVMSHLSFPSTLPPKPSETPRGAKMSGDAELLPTSVVKSPMKPKASTDSARGANSKNPILLTDDDGSASGNGKRSYLASTAGFFASGAPDPKHLGLENVSFTGTPPAKPSYLVSSEVPSSRSAPGSVSAAKPLDTLTPLPLKGSRGYLGSQPWMKAAVERRKAQASIAHLSQHNMDGHLSQPTEVLPNTTNRAQTTSGETSITSTKRMTRETDESPAPNNGNDFDNNVGASNDYRRSPSQTATADGPPVPNRQRRGDQSRRPDSPTSQHPHRDSPARSQTVETLPVSHPASSTTISLLGLASYEETAISDGVVKCVMEGGEPTFQIQFTLEKRQGAAYCSQHASNVKSQDWLHARSRRQRKLCRSPNRSNEAESDAVGEVDRIIARWGSGRHADFLLIWTDKTRDWIPRRDINEEMVSDFEKGYDGIHEGVEILGIRGKGVKKQYRLHWRGRPSKEDGWVAEKLISKQLLHGYEERQSGEAEDVSPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9Y0</accession>
    <name>A0ABR1W9Y0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667784.1">
        <property type="nucleotide sequence ID" value="XM_066812442.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045502"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="147" mass="16178" checksum="B61AA00EAB497290" modified="2025-10-08" version="1">MTKSQKIKISIELKLELPQPSKAKGVQHVHVTEPPPPSVSDPRATDDSGSYPLHVAGGRYGRCRFHGRRGTSVSRGRADCRDSCSNDRCQYYGRCSKSTSREGSNSERPGTSARSNASSPPAESVHCGNTPLLIWGTRLRLRRYKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA04</accession>
    <name>A0ABR1WA04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008158</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667815.1">
        <property type="nucleotide sequence ID" value="XM_066812473.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045533"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17923">
        <property type="entry name" value="DEXHc_Hrq1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18797">
        <property type="entry name" value="SF2_C_Hrq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055227">
        <property type="entry name" value="HRQ1_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957:SF3">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="MZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22982">
        <property type="entry name" value="WHD_HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="382"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="605"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="206"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1152" mass="128804" checksum="B564D8E39B61F019" modified="2025-10-08" version="1">MSTLRAATVSNRVIRRKRKRTENDAESPEAENAEDGSVAGAGSDAGGASGGLSDAEPTKEPAKAAGGSAATKKNKKAPAPKKNANVECVIEWPSLFKDLDRTHRALNLVFTFCSTRKHLATTFDTIKSAVESHTKKELKIEDVAAVATLRPQGVNFTYVDEVMLQTDIKGAERDTTFKSGRARKDIRTQGPAPDASVGGLTGMDELGQHHPDEAPPERRKTGEPTDPNRRLRDEDLKMPVFSQKQMTSLIEKRNQKFINAVSAYINRCVEAKIDPEVMIRQEAEAQMPVPAESEHNTPAPKPEMDTIPKEIPKERKSIPEIVQELKESSWYVKQIVPDGHRVFEPQEAVYGELDFLLSQAMVNALFNAKGITQFYAHQTEAINALENGHHVVVSTSTSSGKSLIYQLPVIHALEKDHNARAMYIFPTKALAQDQKRSLKDMLLYMEGLEQVLVETFDGDTPMQDRNQIRDEARIIFTNPDMLHITILPQEDKWRTFLQNLKYVVVDELHYYNGLMGSHVAFIMRRLRRICAAVGNRRVRFISCSATVANPQDHFRTIFGIENVHLVDFDGSPSGRKEFLCWNTPYKDPGDPSSGRGDAMAECARLFCQLILRGVRVIAFCRVRKQCEVLVSAAKWELESLGRPECMARIMGYRGGYTAQDRRQIEAQMFEGKLMGIVATTALELGVDIGTLDGVITLGFPYTIANLRQQSGRAGRRNKDSLSVLVGDCFATDQHYMQNPDELFTKPNSELQVDLENMLVLEGHIQCAAYEMPIRPVEDAKYFSKDLAKIAEERLIKDELGYYHCHDRFRPVPSKFVAIRDTEEDHFAVVDISHGKNIVLEELEASRAFFTIYDGAIFLHQGNSYLVRDFQPDRMIAKVEKVKVDWTTQQRDFTDIDPVETELIRRIPGSLSSAFHGSIRITQNVFGYFKIDKKRRILDAVQVDNPPIIRHSKGMWLDVPKRALEILVDRRLNVAGSIHAAEHAVMSLMPNFVISMPGDVRTECKIGLKEFAQKETQRKRPARLTFYDAKGGAGGSGISTKAFEFVDLLLVQALKRVEHCYCEHGCVECVCSELCKHANEVMSKAGSSVILKALLNMSIDVEALPMGPEEMSPVGVETVVLAKPVPGKGRIPVVVNDVEVKLEEEEDVGLGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAD3</accession>
    <name>A0ABR1WAD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="11">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_008241</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the C-terminal section; belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667898.1">
        <property type="nucleotide sequence ID" value="XM_066812556.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045616"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF47">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 11" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="12">
        <location>
            <begin position="7"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8080423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="373" mass="40944" checksum="76AA1EC4CC597FC0" modified="2025-10-08" version="1">MAAVGTVLVTGGTGYIGSFTTLALLQHGYNVVIVDSLYNSSEVAVDRIELLCGKRPIFHKADVTNEEELDKVFAAHPEIDSVIHFAALKAVGESGEIPLEYYRVNVGGTMTLLSSMTKHNVSNIVFSSSATVYGDATRFPNMIPIPEQCPIGPTNTYGRTKAFVENIIEDHVNAQRNNLKKAGKPYEHWNGANLRYFNPCGAHPSGLMGEDPQGVPYNLLPLLGKVATGDRPKLLVFGDDYPSRDGTAIRDYIHVVDLARGHLVALNELREKKPGVKAWNLGSGRGSTVFEIINAFKKVVGKDLPYDVVPRRQGDVLDLTANPTRANEELGWKTELTMEKACEDLWRWVSNNPKGYRQEPPAELLNAVKTPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAE4</accession>
    <name>A0ABR1WAE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF292-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667946.1">
        <property type="nucleotide sequence ID" value="XM_066812604.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045664"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.60">
        <property type="entry name" value="Vacuolar protein sorting-associated protein Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005061">
        <property type="entry name" value="Ist1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042277">
        <property type="entry name" value="IST1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161">
        <property type="entry name" value="IST1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161:SF5">
        <property type="entry name" value="IST1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03398">
        <property type="entry name" value="Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="32924" checksum="EEE4475C783AD46A" modified="2025-10-08" version="1">MAPSATLLTRIKVQLKLAIARLRMVQKRDEALSKAARRTMAQLLETGKVDSARIRVENIIRTDIITELHEILELYCELLIARAGLLEAPQCDPGLEEAVKSIIFAAPKTEIKELQAVRLLFGEKFGKEFVMTATENTDGKVSEKVVKKLSVTPPKEELVTGYLEEIARAYGVDWPKRPANLGDPPDFVDDDVDDNPSGGQAQKIVEPGIPADSKAAREREDLSRATPPRTLGPQSPLHVNPPSPSTENPRPKITLNSAELKPSKKMLDAGISGKKTERKGGLGEDVPSVDDLAARFAALKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBF6</accession>
    <name>A0ABR1WBF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008652</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668309.1">
        <property type="nucleotide sequence ID" value="XM_066812967.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046027"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF158">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="52"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="320"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="411" mass="45587" checksum="814F1992D7D3F1E3" modified="2025-10-08" version="1">MGDYDWFLDHTPARKPPPGVESNFVNPESHSYQLIIVIAVMFTLVVLFTGGRIYTRLRITKSFGADDYLCIAAAVFVLAGDLTALMMCDKPGGGPGGTHLWDTTLRKWIYYSKACHFRQSRMFLAIAYAGCAFFVFYLRLFGPKDHVRAMVWAGMTVVVCFCIAFEIGYLVTALPHDGDFLAPDYQARLFGVPQKLITAGAYISVLTDFYIMFIPLHQIPKLGLSYKRKWGISFIFLTGLLATGAGVANLVFRHNPTIMDLKDSTWNGQYVLMTSLCENNLGIVCLSMPVVLALFVGRISALGQSLGSWVNIRRAQRHGAGDSASNLSPSDGNDSGPDLPKQHMPDPKMGGMRKYIRNLNHSRADNTTTVMTTFNDLTSADLSYHHQLKALHPSQTASSRSNKYEKLEKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBY6</accession>
    <name>A0ABR1WBY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007788</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667445.1">
        <property type="nucleotide sequence ID" value="XM_066812103.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045163"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="6">
        <location>
            <begin position="129"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8079970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="324" mass="36843" checksum="FC3B3E7BBD127E0F" modified="2025-10-08" version="1">MDTNMEDAQLAPPMPASEPATIPTLDGWIESLMSCKQLAEADVQRLCEKAREVLQDESNVQPVKCPVTVCGDIHGQFHDLMELFKIGGPNPDTNYLFMGDYVDRGYYSVETVTLLVALKIRYPQRITILRGNHESRQITQVYGFYDECLRKYGNANVWKFFTDLFDYLPLTALIDNQIFCLHGGLSPSIDTLDNIRALDRIQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISEAFNHNNGLTLIARAHQLVMEGYNWSQDRNVVTIFSAPNYCYRCGNQAAIMEIDEHLKYTFLQFDPCPRAGEPMVSRRTPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC54</accession>
    <name>A0ABR1WC54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeats (3 copies) domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668487.1">
        <property type="nucleotide sequence ID" value="XM_066813145.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046205"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="102"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8081012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="222" mass="24117" checksum="22F1F159688CD146" modified="2025-10-08" version="1">MLQLPTELLLEIGAYIDGLSDLLHFGLTCRGLSSFFLDELYSRDVRDGHCWALQWACRTGNLALAKRSLDAGAPVDHQFFDRSMANWAPWPFSDKRMRAACLAGTPLSVAVQHRHLELVRFLLEEKGANPNQVDKWAASYHGQIWYPIHWAVACQAATQSHDACCKVNKQCCGFATNPRPPTSSASSSATAPTPTSAPSPARAAAPATRLASCTGTVCGRCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC61</accession>
    <name>A0ABR1WC61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_007924</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TFIIA subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667581.1">
        <property type="nucleotide sequence ID" value="XM_066812239.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045299"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10014">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10145">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.190">
        <property type="entry name" value="Transcription factor IIA gamma subunit, alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009083">
        <property type="entry name" value="TFIIA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003194">
        <property type="entry name" value="TFIIA_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015871">
        <property type="entry name" value="TFIIA_gsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015872">
        <property type="entry name" value="TFIIA_gsu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10966">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02751">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02268">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009415">
        <property type="entry name" value="Hum_TFIIA_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit N-terminal" evidence="9">
        <location>
            <begin position="8"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit C-terminal" evidence="10">
        <location>
            <begin position="65"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8080106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="113" mass="12665" checksum="688AD0E9D3CED873" modified="2025-10-08" version="1">MATDKQSFYELYRQSSVGAALMDALDDLIMETRIDPQLAMKILANFDRAIAEVLQNQVRARLSFKGSLDTYRFCDEVWTFQLKNVTFKMDSGGQVVSADKVKIVSCTAKPTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WD23</accession>
    <name>A0ABR1WD23_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007877</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667534.1">
        <property type="nucleotide sequence ID" value="XM_066812192.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045252"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF11">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="56"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="516" mass="55428" checksum="AAC67DFA255817C7" modified="2025-10-08" version="1">MAAAPPSAPPAAGQEKDVERSVPTAETSSIEPSDDLEKLGRQRPACFKSGLQEIGFLVSIFGSNLLAEFLISGFNVLLPTLQNQERFSSTAPSAGAWTWPSNVFSLVAGAFLLPVGRLADLYGGRVVYLGGLVWLFFWALVGGFSANYVMLVVIRALQGLGASAFLPAGINLMGSMYRPGPRKNTVFSLYGGARFLYWGWFFWIASIAMAVLSVISWFCVPVDEAPPEREHLTMDWWGCATSVSALILTVYAVTESSKSGWQSPGIIVPFILGLVLLGAFIYVEARVAKDPILPLSIFSTKDIGPLFVALFLAYGSFGIYLFYASFYIEKVLHIDPLLTALWFAPLAGGGLTIALLGGFTLHLLPGTALLALSCAGFIVCNLLLALAPENPNYWAWIFPAMISATIGIDIMYNVSNIFITTNVAKTQQGLAGGCINGLLFVGMSFFLGWADLATASREEFGLRESFKTSLFLGVGLGGVAALIVLVFIRIGKAGSDLTLEERVAQEQGGNEENKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDE0</accession>
    <name>A0ABR1WDE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667955.1">
        <property type="nucleotide sequence ID" value="XM_066812613.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045673"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="78" mass="8406" checksum="A62119F9B808D9A9" modified="2025-10-08" version="1">MFPPEAGRPMSQALVIGFTSTSYPLFLPNQSHQPPTPIPPTIADLPDPAVLWLVDAGERVAPQKTNLRDIWLDAAGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDI6</accession>
    <name>A0ABR1WDI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">T-complex protein 1 subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_008343</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668000.1">
        <property type="nucleotide sequence ID" value="XM_066812658.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045718"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03335">
        <property type="entry name" value="TCP1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012715">
        <property type="entry name" value="Chap_CCT_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02340">
        <property type="entry name" value="chap_CCT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8080525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="567" mass="61621" checksum="5774209699BE8723" modified="2025-10-08" version="1">MASMFEQPGNGTLFLGGQKISGADIRDQNVLATQAIANVVKSSFGPSGLDKMMVDDIGDVTVTNDGATILSLLDVEHPAGKILVDLAHQQDKEVGDGTTSVVLIAAELLRRGNELMKNKIHPTTIITGYRLAMREAIKYMNENISIKVEQLEKESLLSIAKTSMSSKIIGADSDFFAQMVVDAMQAVKTTNNKNESKYPVKAVNILKAHGKSSLESMLVKGYALNCTVASQAMNTRITDAKIACLDMNLQKERMKLGVQITIDDPQQLEQIRARESGMVIDRVEMILKAGANVVLTTKGIDDMVLKLFVERGAMAVRRCKKEDLRRIAKATGATLLSTLSDLNGDEKFEPSYLGHAEEVVQERISDDECILVKGTKTHSSASILLRGPNDFTLDEMERSVHDSLCAVKRTLESGSIVPGGGAVETALHIYLEEYAGTVGSREQLAIGEFAQSLLVIPKTLAVNAAKDASELVAQLRSRHAISQRTQEGDATQDEKTIARMKGYKNYGLDLSKGKVVDEIKAGVLEPSISKIRQLKSAVEACIAVMRIDTLIKLDPEQQGEQDDGHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE13</accession>
    <name>A0ABR1WE13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cut9-interacting protein scn1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668211.1">
        <property type="nucleotide sequence ID" value="XM_066812869.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045929"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053044">
        <property type="entry name" value="Metallo-hydrolase/TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345:SF1">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="39639" checksum="AED81B375BA15E3E" modified="2025-10-08" version="1">MSSVATIPHMKARGLTVMSTRLQDQDLVFDVAREQGVQTKDSLFSPQATHERRFIPSFGWHPWFSYQIYDDTVPGATSYDGSSERSGIQRWTPGPSAPLPIHSRDPGEAGEGTVRPGGEVGLDKAFRIPESWTASTTDAEKTQRDEGLTPGGREGRQLSPHRVSMDHQSAILKAQMKLAGEMDRAASVHGVQVHGALYNVLAECWKGHEKEVLSKREKKKIAANAENFESSDDDDPEKTAKQRQSSSSRKRNRSRRAYYIHPSVPAAVFFSFSVAINWDPEAGAEADKNKKTVDAIRATPDDRILIESDLHTAGDRMDQALEDVCRLVCDIKGWPLREGVGRLARNWRHFVFGDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM18</accession>
    <name>A0ABR1WM18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">DNA repair protein Rad18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_005852</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669090.1">
        <property type="nucleotide sequence ID" value="XM_066810167.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043227"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_GajA/Old/RecF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306:SF6">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease GajA/Old nuclease/RecF-like AAA" evidence="14">
        <location>
            <begin position="153"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="472"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="320"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="775"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="841"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="61"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="483"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="509"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8084581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1181" mass="133672" checksum="828096C209E5D8FF" modified="2025-10-08" version="1">MPSASRVKRSRAAFDEEDAEDRTAHASSSKGAHLLRKKARVSDADTSRSSGRLRHNGQPNSDDDDEIEEEEVEDEIEEEEVEDEIEEDDNDVMRDTEAPPTPPPATQYETMRDAGFQHLWHLDEDDMRATQRLKSRQLPEQIGDNVAALNAVIESITCYNFMCHTRLHCDLGPLLNFIVGENGSGKSAILTAITLCLGGKASSTNRGASLRSFIKEGQDHASLVVKIKNQGSDAYKPDLFGESIIVERNFNRSGSSGFKLKSATGRVVTTKKSDVDDVVEYYCLQVDNPLNVLSQDNARQFLNSASPTTKYKYFLQGTQLEQLDNDLQLFAELMEANENKLVEYEETVTYLKDKFEKARAIKEACDKNEELRRKSRLYVQQLSWAQVAEQETILEEKENAIEAAESEIARLQQEAEAKTEVLAARDEKIQQAEQAADAITQEEASFEEKHAEADAKFRAAKGEIEELHVQERELRSQAKQAKHSVDDKKEKIKEEERQLEEVNGGAAAEAERAVDEAKKAQEDADNNLNDHKDAEPSLREEMIKAEEQVAEASKLVEQKRKEVNAAEGRLRQLSQSRIDSLAGYEPHMAQLLKNIENDRGFQDQPIGPLGLHIKLKKPDWTFILEKVLNDPLNGFIVTNPHDQKRLIEHMRRLRMDKNAIYISKPGFSLNALREPDAGFETILRVLDIDDPRVRDQLVLVARIEQIVLMPRAADVWATLGDRGAPPGVASILALHDTDRNAFMRFQPKGSNNLQSTAEGVYNGASRMKSDSETQISVQKRQHEQLQMDLKELNQSMRLTQQHAQKCSLAVTQHKRQEKALDRQVRAAGVALSDAQSALDAFDGVDARLQALRENLVEAERNYEHYGRQYAEIAVLKEEKNKIVSTLKAELRAAKEEWEDYKARKGKAMDKLQRYKDLRHIALTEKNSAIEHIDIAKIEKQDAEGARDEQKELVHEFITNAQKYNPERVIIPEGETYDTIEKKFTALKLQLKRMRDSLGGTEEEINNRIIQAAEEYNAASRNQQNLGSLMVELKQALSKRLDKWRAFQRLISAQSRANFQYLLSERGFRGKLLLDHANKKLEIRVEPDETRNNVSGRNTKTLSGGEKSFSSICLLLAIWDAMGSPLRCLDEFDVFMDNVNRAISTNMLVEAARRSVGKQFILITPNAIEGRAKVAEDVKIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM51</accession>
    <name>A0ABR1WM51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cyclin-dependent kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_005869</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669107.1">
        <property type="nucleotide sequence ID" value="XM_066810184.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043244"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40468:SF1">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40468">
        <property type="entry name" value="YALI0A15257P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="204"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8084598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="38767" checksum="72CA567A5AC1E900" modified="2025-10-08" version="1">MSSPLKKQPEAVADKVLKRVEVSKIARRLQGRLALAHFKTKHGWEDLTLDTLEPKLDEERRKRNYDGDHLGTPLPNENPHEFASKGSLFSDAIGSSNGSTGHRKRTYMASFDMDMALSSPAKRYRSSPTPHKSFHMGQNNWKSHRQLIQSSPIKPRRQQHFTTSTGPNVSFFQGARRVSVDLASPNFAAPPSDDEEDLFPTHSFQLQPHHSSPPRTPPMRNRSLHGRHKDRNTANNTKGGEEGADLLLYLAASPSPAMPSTRTRMEPPSTPPPKKDLALPSSMMTTPGGGNLFPATPGQPFDFADFVNITPSPAQKPWKTPLGAMSSAKTPISITRRRLTFDEPLVHGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WML7</accession>
    <name>A0ABR1WML7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Voltage-gated hydrogen channel 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Hydrogen voltage-gated channel 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_006038</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669276.1">
        <property type="nucleotide sequence ID" value="XM_066810353.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043413"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031846">
        <property type="entry name" value="Hvcn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480">
        <property type="entry name" value="F20B24.22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480:SF1">
        <property type="entry name" value="VOLTAGE-GATED HYDROGEN CHANNEL 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="65"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8084767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="209" mass="23838" checksum="BB27F81BB4BD56D2" modified="2025-10-08" version="1">MSDRTPLLVRFPESGSLVNGFTFEWRSTYRKARREARCFLSSRAKHWVILGLVIFDVAGILSDIFIALIACELKIEDREWVQPTRSALTTLSLVMSCLFLLELLLCLWAEGIRYLANWFHCFDAFVIVGSFAIDLLEHGVAEEIASLIVILRLWRFVKIVNELSVEASEQIEEVQRRLEDLEKENAGLRRQLGLGGGRQQDEEAALHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQI7</accession>
    <name>A0ABR1WQI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670309.1">
        <property type="nucleotide sequence ID" value="XM_066811386.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044446"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF12">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="29"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="502" mass="56128" checksum="87C0FEA5AFA48464" modified="2025-10-08" version="1">MTHRVPQLRFVDVEESCVVEAAPDTVTSWVALSYCWGGPQLHALQKKNLEAYRLPGALTDQLLPRGIVDAMAVTRALGERYVWIDSLCIIQDDDKDKLEFIAAMGTIYAHAAVTIVNAANDKVALGIPGGLLSPRCLVITRDQVYWQCKTASWCEDSCWEAASSSSSSSAGGQRGEGIYRHYSGSGIMRRLTDRTEENWLTLYEDLLKAYTQRELTSESDRLGAVQAILDVLGGRPDEMGYFWGMPVGHMEMALNLNRRLSDGARRECDAMFMGPDSEIQTAPFPSWSWLGWHGSFRMPTLERTRVGGRLGLKFYRISNGPALEALVEAPFAGPERAFSTKDYLEFQDQYNISYPEGLVHSCMDYNRQSITLADAPPVVLASAKAPSALCFWTSTAVLRMQHEGRNHFHRCPGISLSRGEVSFHGGKWEDDDSFTPDGVEGKFIVVGTERTRMSHGGHVTVNLLLVEQDADGFSRRSRLVTYTPETVWESFENRKWELVFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRG0</accession>
    <name>A0ABR1WRG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669187.1">
        <property type="nucleotide sequence ID" value="XM_066810264.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043324"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="110" mass="12178" checksum="CBDA9CC0232CD27C" modified="2025-10-08" version="1">MTDFIDDRVLDYVPENGNVVPSQYTDWCHPTLVGRDFWTEEPLTQFLEQSFGHPVSPNTSSSEDSLDIPETLHFEEVSELDMATAAAASLLMPTAPYIPNMPYGHASSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWL5</accession>
    <name>A0ABR1WWL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670431.1">
        <property type="nucleotide sequence ID" value="XM_066806813.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039873"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="21263" checksum="2A83F499FEE6A190" modified="2025-10-08" version="1">MASTTTASGSLVYSRRVARVHKYHWPAIQLNVWMIILLIASCLIIGVFATFIEQQQTLNLHIPWYFPYFITVAGLTILFIGGLLWLISQRRLLPAIVIVGAFVFFVLWMVGLIVVSIELWGPTGSVSANCNLLVFDRVPEPANSLANLAWLQQKSICQSWQAVFAFALIGVIFLLWIMVMAIQVFYDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXP1</accession>
    <name>A0ABR1WXP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002897</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670830.1">
        <property type="nucleotide sequence ID" value="XM_066807212.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040272"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="162" mass="18184" checksum="F21324E09BB9DF0A" modified="2025-10-08" version="1">MPPRKRPAQKPSSSSDGDGDADEAPTVLDVDKLVPPKMNAATICIMQSIQVYAEKLTDLMEKFTQRFEEEQNQKEARTRELLLRLDLAIQKKAAAEEKMMQVVASVKHDAETFQHAISCLCAERIEHCKEGVEMADQARQGGGVPLMQGEQKVRARMEKLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY82</accession>
    <name>A0ABR1WY82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671015.1">
        <property type="nucleotide sequence ID" value="XM_066807397.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040457"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF6">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="9"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="343" mass="37460" checksum="5BBDF054C7C359F1" modified="2025-10-08" version="1">MAVKIFLTGATGYIGGDALFVLSQTHPDFEFSLLVRTQEKADKVKAQYPNATIILGKLDDSGLLREQAAKADIVLHTADASDHEGAARAIAAGLAEGHSPARPGYWLHTGGTGILTYLDSEAGRLGEHADKEFDDYAGVDELTSLPDDAFHRNVDKVVLEAASDVVRTAIVCPPTIYGTGRGPVATRGRQVYELARLVLREGYAPIVGGGRARWNHVHVADLSEAFRLLVEQAVASEKKDDQELWGSRGYYFVESGEHVWGALARGMAATAFEMGLLKSEKKPEDRPLDKDEALAVAGFEAVSWGWNSRGRAQRLRKVLGWRPRAPTLGESVPEILEYEKRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ21</accession>
    <name>A0ABR1WZ21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylinositol 4-phosphate 5-kinase its3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003378</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671311.1">
        <property type="nucleotide sequence ID" value="XM_066807693.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040753"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17303">
        <property type="entry name" value="PIPKc_PIP5K_yeast_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="3">
        <location>
            <begin position="283"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="693"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="706"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="745"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="761"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="860"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="893" mass="100104" checksum="2DCF19C23900ABFA" modified="2025-10-08" version="1">MPSFVTNENSPVYAPHNGVVHLNDDQHFPQRIRQRFLPFLRDLRSSSSDEWRSQLEHVAIAQWLPTELRYSEWTQPQYREAQPTKPDRFLESVKWRHTTSPSDRQSTENATASQYAIRSSVDSSARGSLQQTPNDAMPSRPSNDTSQNLSPFAPNAGIQQRFSSPASTSASSSALQPPPGQLKHRHTLEVPKVTGRASKDGVDGAYASGRYSPTVPGPSGRRGSLSLGRKNTRSLHSEAVRDEVVPDDDALRWAEAYRQKRAKKKRKDDLDDDKVLVGTKVDENHANWTTAYNMLTGIRVSVSRTNAKLDRPLTDADFEAKQKSTFDIAGNELVPSAKYDFKFKDYAPWVFRHLRALFRLDPADYLMSLTGKYILSELGSPGKSGSFFYFSRDYKYIIKTIHHGEHKFLRRILKDYYNHVADNPNTLLSQFYGLHRVKMPYGKKIHFVVMNNLFPPHRDIHQTFDLKGSTVGRDYREEDLENNPRATLKDLNWLRRKRHLELGLTKKQLFMEQLQRDVRLMQKLKIMDYSLLIGVHDLKKGNEENLRDKTLQVFNPGGREGPSDEADPNQILMRTPSKLESARKARELRQMIRAERPVPMGQTSNRMPEELEEGEEVYYLGVIDCLTHYGMIKKIEHFWKGLTSDRTQISALPPEEYGERFIKFMEGVTMSSEEAERDALDRENAIRLAEAEAEEEQIGHNLPHPHSAPPAAPGYLPPAPPGLRSPRSPEPNPTLEKASRKAFKKEKDVAKEQDVPDRKISTASPLGSNAQGKGNSHTVLPVVEETAEAGSVSGRSREEQHTSAGRPFTPSAMDTPSVTRPDGFTDLGPHGIGGRGPPTPPKSSYLNTSGGGGYGRKRSGSGASGASSIGSIPRGRLSKDSLDKALPPLPGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZV5</accession>
    <name>A0ABR1WZV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671597.1">
        <property type="nucleotide sequence ID" value="XM_066807979.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041039"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046302056" evidence="2">
        <location>
            <begin position="19"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="153" mass="14345" checksum="10AA180A43BB6BAE" modified="2025-10-08" version="1">MQFFKVTVIACVAAVGMAAVDNIEEDCGCSVTVTQTVTGTPPSSSSSVTTTTVTPGVGSTTPTYGASSLTGTAQTPTPTAVTGSETSGTTGTAATGTDSTATGGTETGTGTTETSPPASSSPSAPPSSAAAAHPAGIMGIAAAIGAAVLIANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZX0</accession>
    <name>A0ABR1WZX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003692</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671625.1">
        <property type="nucleotide sequence ID" value="XM_066808007.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041067"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15534">
        <property type="entry name" value="PHD2_PHF12_Rco1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052819">
        <property type="entry name" value="Chromatin_regulatory_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47636">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47636:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="662"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="797"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="280"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="556"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1024"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="395"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="600"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="614"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1026"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1041"/>
            <end position="1053"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1053" mass="114641" checksum="F40CF597F320534F" modified="2025-10-08" version="1">MLKKPSASAEGTPAPTVKRIVLKKSTKAATPVEETSAMPQMSVAMAAPDAEMALDSLEPSRSSPTQPIFPATGLDDSDDGDYRPNASRTRRSSIHSHHNKKSTKRHSRPGRKSSARAASPAPSVHPEPDIPEPTPAVVEFQPPPALLGRPPIDKAFADKVVEAAVDEALHHYRYPTAWALRTLYDELGDKEPCFVHMIEDIFHQRADIDTIKEFNKLVRDSKTRGKRDNEACNYFIPPDNRTTPHKPKPAPYHDLLQMDFTPVKQTSQDMDGHINKKAKLELDEPLAAGTVRSSSSGSGSHNRRGSHSGSANGGNVGNSSSSRGRSGSSSRPVSKLNLNGASGLNGAPAPARVNGFTTINQNQNPSQSQSQKQSPAKRSSSKHSPSKGKKHRRSSSVSSDSSLSEVPDDEPEDYEEFQKRLEDEISRPSTAEPNHAPKPGDLDQPISDEKTKPTSKKAPKPDGSRNTSTHPFHPHDSDMAAAAVITNGASHQHSHRASTPLKFPSKYGDVSIQDQLTLRKHEAKADTRGLTEDVVLPSFTRKPLDEDLSAVDNALAQAPTEQPRALRTPAANLRATRASRRNNEDAESSPIAPEMDVPSTRGSRAATPSNNLRSTKKQKTGLRVKTSPMKRKGTAAGVPREAPVNSGPSFNDKDRTSSNDDTCYTCGGNGEVICCDGCNYSFQVDACPLCVDPPLHEDDIPHIEDFYCHECQHVFFPSQFTGNRGTFGSLLDNLDKTNSRAFGLPQDIRDYFENVRTGPDGEYEELPAGKPVKVNKKGYDEPFDFYKVRDADGRPVLCHQCLKGASDNRAIIPCSAPNCGLQFHLECLDPPMTIPPVLRTWQCPCHADRPPLASLAPAHRYRKVKSAPIIEQAYTRGMTNNGFIEIEEDDDESEDGFKSRYDYGRVYRLSEKGIKLDFISAVGKKRSQTRHAKAKAPTAATHRHSVEEQQAALNLSQLARGTDGIGQLINAMVSEASPDAVALMAQGDATRIANANLSSLDVKALEVMLAQVEALKKNIAQTLESSRGDGTHSDPKVPKVAQSNGTEDSMQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X032</accession>
    <name>A0ABR1X032_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4 14">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_003701</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4 14"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671634.1">
        <property type="nucleotide sequence ID" value="XM_066808016.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041076"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF3">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00036671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8088740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="223" mass="24709" checksum="53771B4B19CFB430" modified="2025-10-08" version="1">MPPEALLRGLPPPPPIKTGYLILYNAVSAILWATVLGRTVGANLLRGPAFVYISTGDFVLWTQTLMILDVLHGLFGIVRTDPVTAAAQVASRYVAVWGVQFPFPALCASPVYSTMLFAWSVTEVIRYTYLAVKLGGYEPAAFTWVRYSSYLVLYPLGITSEMVQMWRALGPAGHKFGPLYQLFLGVSLFVIWPIGAYVLIGHMNRQRRKVLAAQKKENLKATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X048</accession>
    <name>A0ABR1X048_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671692.1">
        <property type="nucleotide sequence ID" value="XM_066808074.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041134"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF5">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="755" mass="84086" checksum="729ABD71B47C0720" modified="2025-10-08" version="1">MAESASQEPLKASQPWLRSHLRRRRGAASQHPDSADESESWQYIESNPGSVAFFPSPASGSLNSWGLVGFPDQLENSSPGPAAVSPLQLNDHHGQQQQQQQQVFSGSYTDQANASMIASAGMEGQFLASLASDPQLAAAAGQDFMFNDQYNPDFDLAAPFYNAFPNNNQPVDLGIPQQFRNTSDVPPWDPTNLKNDENTFAMTGLHASPGASSCSPQTSPAPSSSSQLSLSPRWVDIKPESAAGKAPIRRTKGAGKIEKKRPEPVNKFVIMTPNLISASAGKPNPYECFDAMRTTARGRKGPLANDTKESALQCDKERPCKSCKKLTHQLPQIVCWQFQDFLPVLFPDFIRGHFKKDQMAKFISENVDGFTVGGSEKTCTVELFSGQRFQSTLTLRALFFTAKSPEVLQHWHMNAGVNSLELESRGAVPIGIDLDNTAVREDVRRKARDYVQSLIFEPQYAEQVTDSVRHTELPRKILRAVQVYGQRSDSPIVKKALSIYAMHYVLTRHLCITHASMAELQNTNLVPRNIPWVTPRLLNRQVKAMLDEHLLKEVTTLFEGFSKSLKPKSRAGWAPCLAAFLVLCLFMESVEAAADVFVVSQNEVDLRNNNRTAPGTASPLSSYNRAFARAVCREIENMPFKQFAYQFHQIYQTHSRDASTKPFNPLVDDSFAELGELDAASLELVMTLRELLQGDSFLPRTTTDYELDFLVADPILPNEDSHPYPRDLSISYTGRLVSRFLLSFLDEKYLFDGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0K9</accession>
    <name>A0ABR1X0K9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Geranylgeranyl transferase type-2 subunit beta</fullName>
            <ecNumber evidence="8">2.5.1.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003916</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671849.1">
        <property type="nucleotide sequence ID" value="XM_066808231.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041291"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02894">
        <property type="entry name" value="GGTase-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026873">
        <property type="entry name" value="Ptb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="9">
        <location>
            <begin position="13"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8088955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="36407" checksum="AE89D943C63803FB" modified="2025-10-08" version="1">MAQLQNLPDELQLATEAHVKYIQSLDSRKDEYEYWLTEHLRLNGVYWGLTALHLLKKPEALPRDATIDFVLSCQHENGGFGAAPGHDAHMLYTVSAVQILALIDAFDELEKRGKGKAAVGKFIADLQNRETGTFAGDEWGEEDTRFLYGAFNALSLMGMLDLVDVDKAVDHIKACANFDGGYGLTPGAESHSGQIFTCLAALSIVGRMESVEADKLGKWLSERQLPNGGLNGRPEKQEDVCYSWWVLSGLAMINRTHWIDRNALFGFILRCQDTEKGGISDRPGNMVDVWHTLFGLTGLSLLGYPGLDEIDPVYCLPKSTTQRILGSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1V2</accession>
    <name>A0ABR1X1V2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Vacuolar amino acid transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004343</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672276.1">
        <property type="nucleotide sequence ID" value="XM_066808658.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041718"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="449"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="614"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="646"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="269"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="145"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="683" mass="74828" checksum="AC706AD438249A20" modified="2025-10-08" version="1">MATRHPSNWDDYDRGASPGRSGSTSSLGQSSSVQFEEQSLLHGENRAQGENWPHRARRRSSVTNRLAAITEIGGVNSLRSFTRSWQRAAVFPEVIPQRPAFVFAPDQEPVQADPITYGRGDVENVAPQTSLLRQHLETTGYENAIEDEETGPSATTPPLLPHRRSSERKGLGNELSRVISPSNSVRSRGSIFEIQPHLASPPIVGSFSSYRSYGTVDSNVSRQSMAQAGELWRQQQEVGADVPEGGRPAILVKEVEQEDGKIVLAVSGQSTLPQTVVNSTNVLIGVGLLSLPIGLKYAGWLCGMIALALCAAVTSWTARILSRCMDLDPTVITFSDIAYISFGRKARIITSVLFTLELLAACVALIVLFSDSLDLLFPGTLTVTQWKIVCTIILAPMQFAPLRVLSFTSFVGIVCVFSIAIIVMVDGLLKPTTPGSLIQPAMTYVFPENWLTLPLSFGLLMSPWGGHSVFPNIYRDMRHPYRYKEAVSITFTFTYLIDAAVAVVGYIMFGDGVRDAITSNLLRTTGYPQALNVLLVIFIAIIPLTKIPLNAQPIVTTLELLAGLRTQVVADDSMLVGRSSVFRGFMKIFIRIFTLIVFLVISIAFPAFDTIMAFMGSALCYTICVTLPLAFYLKLFGHELSNRERVLTWTTMITSLVLSIVGTVWAFLPKHLIGADANVESFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X250</accession>
    <name>A0ABR1X250_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1264-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OBAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672349.1">
        <property type="nucleotide sequence ID" value="XM_066808731.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041791"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010686">
        <property type="entry name" value="OBAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360:SF0">
        <property type="entry name" value="OIL BODY-ASSOCIATED PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06884">
        <property type="entry name" value="DUF1264"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="28396" checksum="361DD56716030A39" modified="2025-10-08" version="1">MASSSMAPADVPGTEVPAGDVALETGAGFIQDFKPVKQICAHLNAFHTYADEPGRYVEANHYCSHLTSGNRLAECSLPFPYPVISFTDLCSQDVRQCILYDGPGPDAKLIGIEYMVTPKVYETLPAEERKLWHSHVFEVRSGMLIMPGPTAPGAQQVWEAAETAEMKEVVHLYGKVYHLWQTDRGDALPLGEPKLMTSFTEAGQFDFDKVVGDRDRRFGVDYKRKRDIRKEAVPEPKIHEDADHAWKQRRNSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X258</accession>
    <name>A0ABR1X258_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004454</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit transport protein particle (TRAPP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672387.1">
        <property type="nucleotide sequence ID" value="XM_066808769.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041829"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14856">
        <property type="entry name" value="TRAPPC4_synbindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007233">
        <property type="entry name" value="TRAPPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249:SF15">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04099">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01399">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="5 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="85"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="195" mass="21786" checksum="661BF8BF29D8D8DB" modified="2025-10-08" version="1">MRLELEEEKTEKLKAVIALLIINKAGGLIYNRTFGEGLNQLNSNDYLVLAGTFHGVHAITARLNPLREHQAAHYYAQQQQYQHSASGSLGGASSSGGGGGGQGGPLPSRPEPPSGLEVMETENFRLQCFNTQTGTKFLLFTDTMQANVDVAMRKVYELYADYVMKNPFYQLEMPVRCDMFDRKLNSYIREINNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X270</accession>
    <name>A0ABR1X270_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672405.1">
        <property type="nucleotide sequence ID" value="XM_066808787.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041847"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="412" mass="45198" checksum="50D5D5A9258D0A90" modified="2025-10-08" version="1">MCAIPFDTREQRGWYKGIEIPAPWQGTPRIGQPISTYSVLQGKAVGNRSSKGNGNGDSKEKPCVSNSPSTTRGAIASVRRSRQQADSVCDDCAIKARGLRPHRVGDGANLPRRKVADESFRKERPDGGRRSPKHKRRNGERKRHSGHSQYTAIPTNANAWIPNLYDEAKQLPSAPPPEYGRKYAPAPPVCPPRPSRSAREPAGSASSSSRKHHEKKSGGSSSSSRGRHGKSSTNDRRGKSATHDQHGKSSTSDYSTREDWPLRAPAEPRPALRPGGLRTQGPNGPPSQCAFATPAPADARPVRPEYTRQRPTAPPAPSRGIKQQEAFAHPLRREQRHVQRHPPPPLKIRPPQRQPLYMEYLEEQNSEMAQRYGSWKPPAPLPTPTMKPKPAEASEGIGVLDQLCGPTLPMAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2A6</accession>
    <name>A0ABR1X2A6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNI-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672426.1">
        <property type="nucleotide sequence ID" value="XM_066808808.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041868"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00116">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="353"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="353"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="421" mass="45960" checksum="9ED9722E66F72761" modified="2025-10-08" version="1">MAAFTKVFSLEGKGLKLDTADDLEAHIADLKSMDHVEEVKMLGNTLGIGACKRLGEVLATKKSLQSANLADIFTGRLLNEIPEALSYLLTSILNLPNLRTINLNDNAFGVNTVAPLVPFLSSHVPLQHLYLNNNGLGPQAGIIVADALSELHGKKEAARKEGKDVPDLETVICGRNRLENGSMLAWAKTFSLHNKVKEIKMVQNGIRQEGISHLLSEGLNHTSVLNVLDLQDNTFTLKGAKALSRVVSKWSEIQELGIGDSLLGAKGAVLLGKALALGKNPKLEILRLQYNDITAPGVKAFAEAAKDGLPALKKIELNGNKFEEEDESVAALKELLEERKEKLGGDVVDEDAWGLDSLSDLEELDSEEEEEEEEEEEEEVEPEERAEKLVKEAEEAQEEPTVQLKDKDVDALAAKLEKTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2E2</accession>
    <name>A0ABR1X2E2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_004547</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672480.1">
        <property type="nucleotide sequence ID" value="XM_066808862.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041922"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF384">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364012" description="chitinase" evidence="13">
        <location>
            <begin position="26"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="14">
        <location>
            <begin position="172"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="86"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="98"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8089586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="554" mass="58910" checksum="22958A99495E4117" modified="2025-10-08" version="1">MRGVLVWASVAPFVVVGGLAAGVAAALGQKRAECSAFSTTTVYMPTTVYVTASEPPASSNSASGTSSGVVATSTSSSVDAVPSASLSATSSSAEPSTGVSPSDSGTASFTVSLSTSTSAVEEPTSTQVPTSDPVASSVTSAIISSSVTSGAPGAPTVRPPGPPSPPPMFRGYKNAIYFTNWGTSGNSSYLPQELPVSELTHILYAFADIDANGTVKSSDAFADVGKRYARDDPLNRTRGHHAYGAVKQLYLHKKRNRNLKTLLSVGGFDYSPKFVPVAADAGRRRTFADSAVTMMADYGFDGIDIDWEYPADADQAQHFVLLLKACREALDRFSFRHRVPYRFLLTVASPAGPVNSHKLDLAGMDPYVDIWNLMAYDYTGSWDNTTGHQSNLYRSPRHPSATKLSTDDAVQYYEGLGIRSSKILIGVPTYGRSFESTSGLGQAYAGVGTEGGGVLLYKTLPRPRARELWDDGAKASWSYNNATRELVSYDTPRSTLYKARSAAPSSGEATGDRAGAASLVNTMSKTLGWLDESPNHLWYPMSQYDNIRWGMPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2P3</accession>
    <name>A0ABR1X2P3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672548.1">
        <property type="nucleotide sequence ID" value="XM_066808930.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041990"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="29002" checksum="2FF6837FEE11AA34" modified="2025-10-08" version="1">MSIPTFEVEDPELENQQRLERRRELNRKAQRRFRTRRNQARIRQIEQDNHLATGWSNDWPWSNSPPTVPLVAQNQTAGHTSVEVDEPLALDISALDSMLYPTIPQGVPLIEPPALSPFQSPATTVAATDSQPLASHAAAFISQDGEHHTAAAQQIYPSWGAADLSGMTLAESPQETIVTNTGSPYMPENSVWPGMMDMSPSQSPEMLLPACFFPPTMAFDPTTIPVATTETTSPMDSQEALNWADMENMQAAFLWSPVPGTYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2P4</accession>
    <name>A0ABR1X2P4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004628</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672561.1">
        <property type="nucleotide sequence ID" value="XM_066808943.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042003"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF1">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE CELB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047210188" description="Glucanase" evidence="10">
        <location>
            <begin position="18"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="426" mass="45096" checksum="449C19389A965A3D" modified="2025-10-08" version="1">MARNMILPALLAGLAAAQKPVGTETHPKLTTYRCTVAGGCTEATNYIVLDSSSHWVHQADGSGCGDWGSGPNATACPTVEACAEACVMEGVSDYATVGVTTAADALTMTLLVDGQTKSPRVYLLDETEEQYEMTKFTGGEYSFDVDVSKLPCGMNGALYLSEMEAAGGKSELNPGGAYWGTGYCDAQCYVTPFQNGIGNVEAKGVCCNEMDIWEANSRATQIAPHTCNQTALYLCEGAECQAEGVCDKNGCGWNNYRLDQLAYYGRGGDFTVDTTRPFTVVTQFPADASGKLLEIERLYVQDGVVIKSETVAKAGTPAVDSITDEFCGATGAARFMDLGALQGMGDAMARGMVLAMSIWWDAGGAMVWLDGSQNGAGPCTQDEDKPDAILAAEPDPTVVFSQMKWGEIGSTFAGAVPTRKHRALRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X841</accession>
    <name>A0ABR1X841_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673562.1">
        <property type="nucleotide sequence ID" value="XM_066806266.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039326"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="91" mass="10461" checksum="C7A7D10489E446F0" modified="2025-10-08" version="1">MAVSPGLLPENLKEKVNSSKTVEEGTRSLLRAFTCMDMPEDPDRIFLSCRGEWWAASKIHHTLDKELQNKWSPGKEALRLEWNREVGYEGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X868</accession>
    <name>A0ABR1X868_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673535.1">
        <property type="nucleotide sequence ID" value="XM_066806239.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039299"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF32">
        <property type="entry name" value="2-SUCCINYLBENZOATE--COA LIGASE, CHLOROPLASTIC_PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="559" mass="60136" checksum="25F5B225FC67DA61" modified="2025-10-08" version="1">MHAKANITTPPTAHEQTFESALWQGHKAQVANPDVSRGQQQRQATLKCATLTYAELHQISLKLAAGLQSYGAQSESTLLMLIPNGVEYPRTPLDMRASPHHLRFTALKHTLRDVKPQIVVAPDASSGKAIDVSVSELGLPQPIRLCLASSTSRGSNPAWKPLASMSDYASRFEPPDEHDSSEEMMAAARQDRPDRIHSIMFTSGTSGRPKGCPLRVSGMSHVLQSQRWLLTPESAAFALQQPHNSRGIAPAQTLQTWAAGGAVVMTGQTFSVRDAAEAIRQLGVTFLVLTPPMVHEMAAELAERPLPDAGASCVKTIQVGGDAVTRDVLVKCARLFPWARVCVNHGMTEGGGSFVWPFFETAPRDIPYFGGDVSRGPVGARVADPGVGRRGGTGLIRGYMEGRSAESFYPDRRGRSWFVTGDVATVDASGLVYILGRSGDMIRRAGVIVMPAVIESSVESFLGVQTVVVPVPHHVLGAEPFAVVSSYGDGKTEAQIKEHVRAALGRDYALAGLASLKQLGLVEFPLNQTHKVVRSELRGLVLKHLDRQKSIANGKCGDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X879</accession>
    <name>A0ABR1X879_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673704.1">
        <property type="nucleotide sequence ID" value="XM_066806408.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039468"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="631" mass="71531" checksum="889DBA3540806611" modified="2025-10-08" version="1">MKGNGASVELRCRQLHGPAGPGWDISQPSWPVRRRVYIEAGLLIGEDIILQWRWDCNYRDPDSQVDEGYRFVYNILQTCKAVYDEVRGLVYAENRIIVDQRNVVYGLVQLRRLSPRACSQLRSLYVHLYLEAPPDPIRYKNDKKKFPPSPPLERGCVVEAWQAAADYVLAHANREELRLQLICDTGHKAATTNVLGPLIAHPGSLRDCEIRLAPKRDDKLCSLARNAALRVKGLDVELHDKPVRFMDLPPEIRLHILEYTDLVTPCKEIEWRPGCRGGFSVTFADRAYRHQTDACYTTRREAQGWRRFVNCQSSSSSHLLPTQSLSSSDTHRTGSVCTARQSGYAPRCQCWAPPRALLLVSRALHDEAIATLYAANRVIVRPELGWHASSSELGHHGMSQTVLHPTRRAGRTQLNAEQFLARRPAAALSRLRTLELVFPGLLVGATTTSSDDDALCVAWRAAVRRLREQQGAGLAALTLVVHMRLAIDEPRISTPWFPHRKRDVSGPPDTWCIMAVDGRRHFECYVEYLTERRGVDEQNTWTAHAALLEPLRELCEAGLRRLFVFLESGWHWSPPRGCTPQSCQGRRGGEVHDRIREMEQVLEKGVMGEEYDSAAEGKMEELPSQWMLHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8V8</accession>
    <name>A0ABR1X8V8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673883.1">
        <property type="nucleotide sequence ID" value="XM_066806587.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039647"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF1">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="195"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="757" mass="85796" checksum="6B96DA5758AB1D69" modified="2025-10-08" version="1">MHMDAPSLPVQHELSYIKMACSVYLSIRAGLTWEKDSYEDSIVVYHGTIGEVFGKPCLGHDSLLRFILPESFFTETPPKPQERLLIRFHGNGSTQISWTNRSSPFPRENDSFTHGLICHLLLLDPSCKLPTPGLGRILDPDWVDPGLLQEWMHECLTEHRDCCDNPMKLAQISSPSWLIDTTKHCIVSGGGIQEYVALSYRWGGGTAHLQNELSILDTLRLPGALLQARFASRVSPTVKHAVGLTRLLGERYLWVDALCIVQNNEEQTRAQLQLMGVIYASAKLTIVATDGDANHGIPGLKGVSPPRELLQPKFSLGKSCEVVVRQNPDMGCHRSSSPYFKRAWTFQEYSLSKRRLVIGGNQFHWDCSSAMHHEDMYGADVLSRTLNNRFRFPQILLGKPGFDELTVLINEYNNRELTFPEDALAGISGLLSLVGRSFDGGFIYGLAVTCFDSALMWTAPSLPMQRRIHSGKDHTILHGSKLPSWSWLGWKGYTFAIDEHSGELFEGSLRRPITKRITQWYIQETPTSSTKYAIRSTFLDHDGDFFKKDQSESLLKEGWTKERFDILKYISVNGKGEEGEEAFHVLGDYVYKHPSLPGEYYWRPFPIKDIVGNPSIDMPLPQWPFLSCDTKRGMFAARRSRRPNYSRELVPAQLCVLGRGGHGRCGYLQVSSDEHAAEFPAADVDESRTIELVAICLQRRLVVRRYVVVVDPPQFREWYGVLWIEWVDGVAYRKGVGYIKKESWESHDLKDIHLVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X948</accession>
    <name>A0ABR1X948_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">UEV domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_002408</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674019.1">
        <property type="nucleotide sequence ID" value="XM_066806723.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039783"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11685">
        <property type="entry name" value="UEV_TSG101-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052070">
        <property type="entry name" value="ESCRT-I_UEV_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017916">
        <property type="entry name" value="SB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008883">
        <property type="entry name" value="UEV_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306:SF3">
        <property type="entry name" value="TUMOR SUPPRESSOR PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306">
        <property type="entry name" value="TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05743">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09454">
        <property type="entry name" value="Vps23_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51312">
        <property type="entry name" value="SB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51322">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046227234" evidence="9">
        <location>
            <begin position="27"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="UEV" evidence="11">
        <location>
            <begin position="19"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="SB" evidence="10">
        <location>
            <begin position="469"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="160"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="250"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8092047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="534" mass="58333" checksum="78AD187776238A53" modified="2025-10-08" version="1" fragment="single">MAVQQHVLNWLYSVLTSLALITRSNPGALQEYHNVNRTYNDVAQALSVYPSLSPRTDVHTFDNGVSALLVHLTGTIPVVFRGTTYRFPISIWVPHAYPREAPLAYVTPTESMMVRPGQHVDPQGRIYHPYLVGWLEFWDVKILHTRLPSNTARRVCQRAPVIARQQPPRPPQPEQSTATPPPPIPPLPAELSRTPVHTQSPAVGDRPPPPPPKGHDGPQVVPGQAINNNGPPLPPLPHEARQSHAPPLPTQQQQQQQQPPPQQYSQAPGQQFHPQQQPGPYQQPAPQPGYQGPPPPGPGLPPMSPNYHDGNQGPPYAGQPPTWQPPHPQQPMHQPPIQPKPKPPPPPDIMDEPLTLSLPSPSNIPPPPIPPNPEKDALLRQLASTLYTLRMRARQQNESSLAGLTAQRNAMLAAAQNLQSDASNLAPLSAMLSSNTAVLQSSLHEADRVISNSRTQTPPGIDELLVAPTVVGNQLYDVVAEERTLGDTIFMLGRAVERGRVAPAVFAKTVRSLAREQYLKKALARKIGKGMGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA36</accession>
    <name>A0ABR1XA36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674245.1">
        <property type="nucleotide sequence ID" value="XM_066804472.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037532"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="49678" checksum="004FAB478408627C" modified="2025-10-08" version="1">MPDSLIRRCLFECLPTELLLKILSGLPDLTSLDSVLHASPTTYRIFDRYAVDITETILACDDEIVVSYHRHPCRTDEVHHGPHPIESGVTCAYIRVMFYMMAAIRSSRFPIHSLSDFCQNVIDPFWWETTRRGRSTLGYYMPENLPQDAPPKVVRSLIATYRKLNWFSLDCLKSCLTRLESVCPSRPAMGKKAFRKGRRAGTVQNNAEGLDQVPGQPVVVLVAGPPSWVEEQRVSRAFWRLQFLYDMQRAARGALLPTACPAEDVELLRNYSQTQLLSLYGLPHPHDGDGYARLHPEIEEIYSVAQYLETAHGCHWPDEVVPTTLPGSRSRSLQVSRSGESGWWPLPRHERRGDKKLAMASPAVRLWPGLTRHLAGRELAPVTRCAGFAFWSDERLRGRGLMGGQPEVLGDWGRFKYAFAWRSLVKGYQILDGEMPACG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA46</accession>
    <name>A0ABR1XA46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674364.1">
        <property type="nucleotide sequence ID" value="XM_066804591.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037651"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="171" mass="17049" checksum="007CA3EF6FA69599" modified="2025-10-08" version="1">MPSLHSNREVHPDGTTTNTTTDGSTVRTDDASARPDAGLGAKLAGDAKGGVAKATGSLQAAAGAATHNEKLKQQGLDKMQAEDQRLATKHGVMPLGSGLREKASGQPTAEHIPATTAGTHAHHDDTTAAATTGNAANTATTTAGTTTNVPTSHGGVHEGGHAGGNPVRDQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAE3</accession>
    <name>A0ABR1XAE3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_000366</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674454.1">
        <property type="nucleotide sequence ID" value="XM_066804681.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037741"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="98"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="134"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="404"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="510"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="226"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="256"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8093681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="589" mass="65197" checksum="AC831EBA1A3D3661" modified="2025-10-08" version="1">MKASDAITEVGLTMEESQNQRDARLEQLWKKLDYQSKGELDWKGLQRGLRKIDHPLKNADDLLKKMTKLVDANGDGKIQYEGEASVLAAIEFRTFMQATERQLYLLFKSIDRDNDGRLDKDELQIAFQHAGLAVPSRRLHAFFEDVDLNKDGYISFDEWRDFLLFMPNNPSSTTLGAVFTFYSDVVVLNSEGDSVISDETLSGIGTKFNFLIEALFGSIIRLASPPDAPKSVRPPTDSPHSSSQSSIHLSQDDSPTHNAHSATESHQAGTTSHHGHISAAMSTTVNRAVAHAHAPTSQHAADVDESWELIPEITEDDSEEEFGLMNYLPGLGYYMAGAAAGSSTRAAVEAAQKGQPVAAVKNFNRSLTRAFSELYREGGLRGLWAGNGLNVIKIMPETAIRFGTYEAAKFIAGGVAGMTAQLCVYPLDTLKFRLQSEYVRDGERGRTLLLRTWRKMWADGKTAPYRGVTMGLVGMFPYSALDMFTFEFLKERYVRYAAKRNGVHEEDFHPGALMTGFMGGFSGAFGATAGTTMHPARYTGIVDVARRTWQHEGLRGLYKGLTPNLLKVGPALSITWIVYEKAKILMNLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAM9</accession>
    <name>A0ABR1XAM9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674422.1">
        <property type="nucleotide sequence ID" value="XM_066804649.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037709"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2790">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="35759" checksum="1D06551415EBE944" modified="2025-10-08" version="1">MRRRQNSSLSSNSARGLPHHIRQQSKAVQPIEAKSQHVSDPFLQSFLSPTFDPASYLNATLPPLQAHVSSVSSSPEGALNAQTTRLTNTLTQLTDDILRSGSRLAYEVELLRGETLSLSEALSDGLQDDVAKFVPNGLQAQLDSKKNATDEVAQRRPSVGTPAPTDTTPKSATMEDPAYISQLQTLALVRSRLDSVIKTFGDAMEFVFPPSELSVTSGFLSVSAPDAGGHDHSTEEKGQQVLKQFKEDIITLLSTSKDPVAGIEKAAQRIEELKELLVLVEDRHKELLEQNNKREPEAAPRKSAEGTVENKPLGGYGLMSQLQKLRGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAW9</accession>
    <name>A0ABR1XAW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras guanine nucleotide exchange factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000464</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674552.1">
        <property type="nucleotide sequence ID" value="XM_066804779.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037839"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF348">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR RASGEF, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="279"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="512"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="173"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="422"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="768" mass="86079" checksum="BE11C7224C8AC070" modified="2025-10-08" version="1">MESINIAAIGANGVGKSHFIQRAIGLPKAPGPQPTAARIFIDNVPYAVTLFELDLEYFDVNPERQIQWPRQIGGTMMPAIDGVLLLYDVMNKESIMELPQTLTALVNSSLPTVLVATKCDNPENVRQVNTEALAAACQSCVSDFKTSASKPENSRNALFRLLKVLVMNRQAEASGTRRRAASVAHLDTPHDSTGTRPMSQHSKHSRASSDMSLVRGLPPQSAGDDNQTVSSMLRTPGIRLDRHNTTPSFLDIEESDGESFHYNDDIPILQRNDDISFDRPAKKTGVTFDELVDRLLAPKMSRSDSNFADVFLCLYRKFAAPGELFTAILTRLDQVKEDKSVHYLTKTSSQLRIIEVVAKWVASYPGDFARPTTRKTLEDFIKHLSSEPIFAAAAQQMRRNLEFSVFEDDDTGWAKSDVIEEDSASGASSLGRPDGPRGSDVTESISSLSVEDHNPARRPSATSSLNTDIGTTKVHQFQFHSYEDYEREAATMVPTYTMPLTKFRYHIFMDTSDDDIADEITRIDWVMFSSIRIRDLVRHVSLNAQQREKSRGMKNVNRMVTHFNHIAKWVANMILMRDKAKHRAQMLEKFMSIALKLRQLNNYNGLAAVLAGINGTAIHRLAQTKALVPADVQKRFARLVLLMGTQKSHFAYRLAWENSPLPRIPFMPLHRRDLVSAEEGSMTFIGPEGDRVNWKKFEVLGEVCLPIMKSQGTPYPNLTKHDVARELILDCLMPIDDEDIYQRSVTVESQGAGGYDAGKKKFPWFAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB96</accession>
    <name>A0ABR1XB96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Efflux pump FUS6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000543</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674631.1">
        <property type="nucleotide sequence ID" value="XM_066804858.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037918"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF94">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="492"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="496"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="535" mass="57577" checksum="4ED55AC0D5499798" modified="2025-10-08" version="1">MVVALDSSIIITALKTMTVALGADTTQGFWIGTSFLLASTVAMPPSRASARSSAAPPASCARSPCSRSAASSASAARGVRLLLAGRAVQGAGAGGIWMVSLLLLTDLVPLRHRPKWWAVISLGWAAGLVMGPLVGGAIVQRTTWRWIFYLNFPFCAFGLVVTPWLLTIRPRAESMRVKLARIDWVGGALFTAGLTLFLFALSSAGIQFAWSSAEIIATLVIGFAGLIATGVWEGFFAKEPMLKHRLFYNWSSNIAYFGGFVQGLVMYGENYYVPFFFQSVNATTPLRAGINLLPALLFVIPSGAVTGALVSRYNNYRYAIWLGWFFVTISCGLEILWDADVSTGVWVVSLIVMGIGHGIVLNAQTFACQAMAQPGDIAAAAAMYGFVRQLGSAVGVCVGSTTWQNVAALKLGWEGLPVEIAYHAEAYLDEFHISLPDGGGDDPTRRKAVTSAFVFGFVGVWQVFLGISGVVFVLSFFVRHFDMDKAIESEHRLEQNSGASSGSGDGNSNMDRRRQRQPGRISRLLLLLRSKPGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC06</accession>
    <name>A0ABR1XC06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000813</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674901.1">
        <property type="nucleotide sequence ID" value="XM_066805128.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038188"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="33"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="298" mass="32690" checksum="F12D449E9B1890A1" modified="2025-10-08" version="1">MDSLHPSELQNQRLIIAVVTTCITLATASFALRCYSPLRQGGSKYWFGDYWMAGVLLLCLGMSASEYIGVQYGYGTHASHLSPDMVMGFKQNLYASMLLWTVGTFGVKIGILLSYWRLSPPPNHAMFQKCIIGFAVCSICLFFVNSIGLAAQCLPVSSFWAATPGPAQSQCFNRTSFYFASTSINSLLNIGFLVLPLPVIWSWQTSRRRIVASALLFMLGIFALVASIFRVAVVSLIDWNDVTCRSLAPSRKNSIAKIVPDTFVSYNIWGVIEVLVGFTCANLLSAGPPDRQVAAHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC86</accession>
    <name>A0ABR1XC86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DSC E3 ubiquitin ligase complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000872</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674960.1">
        <property type="nucleotide sequence ID" value="XM_066805187.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038247"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="260" mass="29366" checksum="97F640827A28C29D" modified="2025-10-08" version="1">MSFTNAPISRGLVYGLIGTSIAASLLDVKHYCYILVDTHLWRFHQTWRALIFQLCYTNSSEVLFAGMTLYHMRTIERFWGSRKYAHFNPGILAFVLRPLTLGLFNYLPAGPTPVIFAVLAQYHAMVPHMYKYRLATSSSAPANGQVPGITFSNKSYIYMMAGQLALSQWPGSLLGALIGWVVGYSWRMEILPRSLTKWRLPGWMVGVRTQRRSEEFEGLRRRLEGEDASTATTSGAQIGGEAGRRRTMGQQFMDTFRGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCB3</accession>
    <name>A0ABR1XCB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001025</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675113.1">
        <property type="nucleotide sequence ID" value="XM_066805340.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038400"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF123">
        <property type="entry name" value="GMC OXIDOREDUCTASE (AFU_ORTHOLOGUE AFUA_2G01770)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="3">
        <location>
            <begin position="164"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="299" mass="30961" checksum="29967259A6C9C842" modified="2025-10-08" version="1">MGSIGMAARKSDGQRPLPREGASAACPARICPVGRGTYVTNLAIGGHDAHGEDIVGPESIQAHGVAVTATENSPKRAYAVAVARLNKGPRGGSAGNGLIDTGASSDGSPSSVSIEIDLIQASQDVSLAYRPESDDLVQPPALSFCEAGLAYKFSFFPPRMHTSLPPTPPNHFSTRLDRDTLVHAAQMTLKAIMSTKSMESIVEGESPPAGEGLDGLIPLAADSSLETIEERIRQTGLAHAHPGGTAAMGKVVDREGKVLGVKGLRVTDASIIPIPLSGHPQATLYAMADQLTSMILGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCD5</accession>
    <name>A0ABR1XCD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid/polyamine transporter I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001001</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675089.1">
        <property type="nucleotide sequence ID" value="XM_066805316.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038376"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF14">
        <property type="entry name" value="GABA PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="525" mass="56661" checksum="86086073A9F2BED3" modified="2025-10-08" version="1">MDGPHPTTGVVGATTDDATILEQMGHKQELKRNFSMISMLGLAFAILNTWTALATSIALALPSGGPSAVIWGLMVAGVCNLCLAASLAEFLSAYPTAGGQYHWVAIISWKRWSRGISYVTGWINVSGWVALTATGGLLGSTLILNIISLMNANYEEKPWHQFLIYIAFTLISLVINAFGTRLLPLITKAAFFWSVAGFIIISITILSCAAPNFQSAKFVYGSFINNLGSWVFLQGAFALTGFDGVAHMIEEIPHPQIQGPRIMLYAIGIGMVTGFVFLSCLLFCVNNIDTVIESAAGPLLQIFMDATKSPAGSICLLMFPLVCMVFTSVSLLATSGRMSYAFARDRGLPFSHVFSKVHPTLEVPLNALLWTAGWDIIFGCVFLGSSSTFNAITAASVVALGVTYAIPPAINVLRGRKMLPPTRAFKLPEPVGWVLNIVGIAWAILTTVLFVFPPETPVTPDNMNYAIAAFGVMLLIAVTTWFVDGRKHYVGPQVDVDGLLNGKVEGMEPVQTRESYPDPTVEKKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEG2</accession>
    <name>A0ABR1XEG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001767</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675855.1">
        <property type="nucleotide sequence ID" value="XM_066806082.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039142"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF14">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="7">
        <location>
            <begin position="142"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="98"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8095082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="530" mass="58131" checksum="D3CEB6BF7C5EC758" modified="2025-10-08" version="1">MRKLVQKHVIIIPHITPPVSSMNRSISPPPLKRQKRSQTASGTAGTNVQPVFSPPITPTLGTLRIFSWNVNGIAPFVQPYLNKSIKLFFGAKSLLSSERKRRRDGEEAGVDVITDSDSNGDVEGPAQGSPDSDLSKEGEPSLRQVLRRYGWPQVLFLQEVKIKPGDEKTQNAVRVAVNDARPVAPERAAPRSEATGEDAGSSQAAILADGGPGYDLFFNLPADPHNAKGFGGKVYGVAAIIRRDFTKSHVNEVRDVTWDREGRVQIIETRDLSFPLGDHDQPSSSSSSSSKTTKLALFNIYGVNGTTNAYRSTSTGAPAGTRHDRKLAFHADLLREARALESRGYAVIIAGDLNVAPDKRDGHPRLRTFPAQHVRNREDFRAKFLRGRLVSTAPNQASYKRLTLPLTDTQGECGEVIAKGEGDSSATPSGKMPQSTTITPGLNGIDTFRHVHADERRYSYHSRGRPWGSSCDRVDLIVASRALEKDIVNAGICDSPRDRGPSDHCPVWVEIGRPSCWDWWAMMELCPQYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XER3</accession>
    <name>A0ABR1XER3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675860.1">
        <property type="nucleotide sequence ID" value="XM_066806087.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039147"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF4">
        <property type="entry name" value="CAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046973382" evidence="2">
        <location>
            <begin position="21"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8095087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="275" mass="26883" checksum="D0555FE1EFF6F0A6" modified="2025-10-08" version="1">MYTGTSLLALALAAASVVSAHGNVQVVTGNMGGNGTALGIKGAVVARFGKNAATEKDTTVFPNQSANKPLTDGLGKTTANGNLKVANTLGDAMALSGNTLPQVSADGSGTITGTWRTVTSDGTAINNQGDLNVVIDPTGTGAYSKGTLLKATSTMVGNGKGNVVQRALAAMGIRKRATNVGADASFSVKIPAGTTCKGTDPTTGVSNFCLMKIANNNNAGPFGGNIAFQVAGAGGAAAAPATGNAGAATGGNAAAKGNNKAANNPNQKNARSFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQB2</accession>
    <name>A0ABR1UQB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660524.1">
        <property type="nucleotide sequence ID" value="XM_066819639.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052699"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF10">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="258" mass="28118" checksum="A3B93D6B78956F33" modified="2025-10-08" version="1">MSAEQPTVVIVPGAWTPPEAYHKLRNALEAKAFTVYVPTLPTNNGHRPPDSSFDDDVQAVRQVVQRLVKNDGKEVIMLMHSYGGVVGTTALRGLTRKDRASQGLPGGVVHLLYAAAFLLALDQNIRTVVQAVNLTRGSDGLVQFADDGTWFPTDPVSLLYQDLAPEDQEEQARLLKWGNAVVLTGNTTYGAWMDVPTLYVRATEDRWLPPAFQDFCVKNAVDAGVGIRTAELRSGHSPYVNFAGELAEMVVQISKSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTL9</accession>
    <name>A0ABR1UTL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">Cytochrome P450</fullName>
                <ecNumber evidence="15">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="15">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_014378</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20 21">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="15">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="15"/>
    <dbReference type="EC" id="1.6.2.4" evidence="15"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660880.1">
        <property type="nucleotide sequence ID" value="XM_066818692.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051752"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06206">
        <property type="entry name" value="bifunctional_CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11068">
        <property type="entry name" value="CYP120A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF127">
        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 15" id="KW-0274">FAD</keyword>
    <keyword evidence="5 15" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 15" id="KW-0288">FMN</keyword>
    <keyword evidence="4 15" id="KW-0349">Heme</keyword>
    <keyword evidence="12 15" id="KW-0408">Iron</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 15" id="KW-0521">NADP</keyword>
    <keyword evidence="11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="16">
        <location>
            <begin position="487"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="17">
        <location>
            <begin position="661"/>
            <end position="904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8062281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1048" mass="116610" checksum="C200259FF96EB72E" modified="2025-10-08" version="1">MTEPIPSPAGLPFVGNILDLQDEVPFFAIGRLLDIYGPIVKFNVMGSEKVVVGNFELFDELCDETRFYKLVSGPLVEGPFSPEVRGAEGLFAAIDERRDDWAQAHRILLPAFGPLAIENMFPEMHDIASQMVLKWARQGPSHHILAPEDFSRLTLDTIALCAMDYRFNSFYQEDMHPFVKSMNNLLTERSNSAQLGGMLRSLMPSYREQLKQDSDLQFRICQEVVDHRRQNPTEKKDLMNAMLYGKDPKTGETMRDRLIAVNMQTFLIAGHETTSGLLSFAFLLMLKNPKTFFAAQQEVDRVIGKDKIEAKHLRELKYINARAVRPENTEDFVCIGGGRYAIPRGQSIICNLMKIHTDPKVWGEDANEFVPERMMDGKFEKLPKNAWKPFGTGVRSCIGRAFAWQEALLATAMILQNFNVELADPDYEMKIVQSLTIKPKDFNIKVSLRSGITATGLQHRLQTVDVPDDIRKDSDAKALESDEPTGMTILYGSNTGTCQALAQKLASQASQHGINASVNDLDSSIDKLPTDSPVVIISASYEGLPPDNAARFVAWLEHLGAGALAGVKYAVFGCGNSDWTATYQRIPTLIDDLLAKAGAERLTAKGATDAKMGDIFADWDAWTANELWTHVSSDTKKENVPVRPTIEMDVSKADRAAHLQQNVQWATVTSTKKLTNEEVSEKRQIEFELPEGVTYSSGDYLAVLPLNPEDTVRRVVKRFGLPWDGIITINKSGSTTLPTGKGVSIFDLLRGYVEIGQPVTRKDLELIATTVQDEADKASLLSLAADEAAFREKIAGPRMTILDLLEQHPTCTMPFPEYLALLPPLRPRYYSISSSPLASPNTCALTYSVIDEPSWSSTTSRFVGVAGTYLRSLSPGDKALVAATPIVMICAGSGIAPFRAFVQERAVLIRERGGKERARLAPALLFVGCRSAGADRLYGEELEEWQKMGAVDVRYAFSRDDSEANETKECRYVQDRLLRDRADVLEMWDQGARIYVCGSGNMAKGVGQAASQIVMERRRARGEEVTEQDVEDFKVRMRNERFIADIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWF3</accession>
    <name>A0ABR1UWF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014488</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660990.1">
        <property type="nucleotide sequence ID" value="XM_066818802.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051862"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050832">
        <property type="entry name" value="Bact_Acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="227"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="416" mass="46388" checksum="5750CA1FEBFEBE32" modified="2025-10-08" version="1">MASHPAISATAFPALSSLTYEQLQQLYVKNKAELTKHVNEAMGVEEKFYGGHDWFVRWWEAPPHVMLQQQQQQQRQPQEPGNSSSGAAITNLAISNLAQDHNGLEHQTIPASEQSEAVNMVKNRFRRRLQRFNWVTGPQRQPDLERVLEGSGFSCQEEEPVMCADLTAGESIPDNLVSFGGDAVAPSSSSRLSTLSDLQAAQNDLRRFLPPHYSSPSPPARLLPEGVVIEPTSSLGIIGWVSAWAHGAPECDVLHWTKVYARVATSVYRDQFRMFAARRGSEVIGTGYLHCHSGIASIHSLFVHPAHRRRGIGRALVLYAMQEARAMGYQVATLTATAPAMDLLKKLGFKEFGAVKLYTWYPVVLPSATREQGRKCAEEHQRRQKQELVSLAVAEAEAKMKEMEVKDAEDEDWEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYB7</accession>
    <name>A0ABR1UYB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014875</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661377.1">
        <property type="nucleotide sequence ID" value="XM_066819189.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052249"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="5"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="410" mass="45157" checksum="B2D1FA32128130A9" modified="2025-10-08" version="1">MASSKVLIIGCGVAGPVIAMLLKQKGYNPIIFERAETQEDIGASLMIAPNGLKVLDLVGDVSRRLLENGPNVEWMLEYKADGKALGSSDIPGRGVDLYKKPAVGIKRTLVASWLRDMAKENGIELREGWSLEGIDETDNEVTAHFNGGRSETGAFFIGCDGLRATSRKLLLARRGISDGLPRFTGIVQINGMGPTPASFRGKPALRNWYGVGMNIVCYPITHEHTSWGMSLAEDTGKEASWGLYDSETRQAILSRLVERLRSEGWDNDVVELVGGAQRLIKYGLFDRPPIEAEQWYNSRCVMIGDAVHPMSVHVGQGANQACEDAYYLSQQLPAYDPAGLSTARLTDAFSTYAHQQQPHVEMVAKSARQQGAIRVVPAERREERDELVRRTMADKQGLQAKYDAVFTKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1F0</accession>
    <name>A0ABR1V1F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661773.1">
        <property type="nucleotide sequence ID" value="XM_066816081.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049141"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9073" checksum="AF645501020D8758" modified="2025-10-08" version="1">MSISTEVIVALALGLPSLLVAAVALWIAYLSYAHSRKPPPLMNRIPSWPSQYPLLAPGGTWTSSGFSFNGGLMAPQATARYRING</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1K0</accession>
    <name>A0ABR1V1K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661787.1">
        <property type="nucleotide sequence ID" value="XM_066816095.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049155"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="1">
        <location>
            <begin position="158"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="311" mass="34481" checksum="A0F8A9F7770F6ABB" modified="2025-10-08" version="1">MPPRKTTKVIPEIKQALTFKHSQLIGLDGKVDPGIIINHDKTVMDPLEADIKKLVASGVLPNKARLEKVLYSATQAYLETGRRPRWVYPLDELKPGEQFELVPWVILIRDPESNTLYAFSKGTNFWSTEIFNSTGFKSVGFNHDDRVPASKIFPGCDNGEVKKSTWDWLNSKYYCKGANGEKRTLSLSLLEQIDQYIPLGFESEPEFILVGHSAGTTIGNVLFAKIGLASVKPRSARAVFIGPYAVFTRQAAEYMESVAPGEILNIVCQNDPVTRGPTAGQSVKTALTSVDTVYSKTENEKAYKDYKAVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1V9</accession>
    <name>A0ABR1V1V9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661940.1">
        <property type="nucleotide sequence ID" value="XM_066816248.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049308"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF102">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="508" mass="55435" checksum="B2F0D0EA29693DE1" modified="2025-10-08" version="1">MDFKLTQPGSSGVGAGSTVSPASPTQGSQASLPHGPQEQTPTNPANSSAPPQAQVEAANNSEPEPPTTSPQHEHDTPKEKDAAPAIEEAAVPAGSPHPAQSEAAARSDVRLQSPAFGTGQAANDEEPTASEDATTTTTTTTREALSEPATEQETSQYPIADEGAFSSSSSAANEPPDQLLTPRILPPGPTTKKARLASWMPHLASVSSTASVASSIFEFVEENGRTYHRYKEGNLQHQICTKLFKGRLALAPIENPIRVLDIGTGTGIWAIEFGKILLFSDTGSDTGIELNNDSASTSQLGRSGNRHQPHPTRICPPNCRFEVDDLEDEWIWSYKFDYIHARHMVGSVSDFPRLFRTIYENLNPGGWVEFQDYYVKLDSFDGTLDGTALQRWNAMINEALVPTGRSGLNSAHYAGWMREAGFEDVVQEKFAVPGNPWTRDKTHKQLGVLQRTNILEGLHGISISLFTKFLGMSTEEVEVFLADVRRDINDTRIHFHYPVRVVYGRKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2W3</accession>
    <name>A0ABR1V2W3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012277</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662283.1">
        <property type="nucleotide sequence ID" value="XM_066816591.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049651"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="241" mass="26612" checksum="03297B33FB781600" modified="2025-10-08" version="1">MSSTEYTIQQYLLDRANIQDTVNKIVRQPFPLPFSHISPNHCQLFSHPLPRDQQTLYYDTDNAPALADECYAPGDDDAVTIDYTSMFAGRPLTISNRKWAADAVSMLRAFDAKQHVVTGLVIERLPQPAVTIAAAAAGTHVVPSIPDSCTVVANVNGHVMRKAAAAEAAESAEFASSFIHNGVSLASLHGRYEFDLVRIKELEEAGKNPWRVRKHKCILTWSDGNPRVMEPMKDAPVVTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3B8</accession>
    <name>A0ABR1V3B8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein MAK16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012430</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the MAK16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662436.1">
        <property type="nucleotide sequence ID" value="XM_066816744.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049804"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006958">
        <property type="entry name" value="Mak16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405">
        <property type="entry name" value="MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405:SF4">
        <property type="entry name" value="PROTEIN MAK16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04874">
        <property type="entry name" value="Mak16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003352">
        <property type="entry name" value="MAK16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="7">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="202"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="202"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="213"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR003352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="324" mass="37527" checksum="1A708172BF2A9965" modified="2025-10-08" version="1">MASDEIVWQVINQQFCSFKIKTTKEQTFCRNEMNITGLCNRQSCPLANSRYATVRASANGTIYLYMKTIERAHMPSKLWERRKLSANYQQALKQIDEWLIYWPQFLQHKAKQRLTRLVQVAIRSRRLAKEEARLGETIVPKLAPKIRRREETRERKAEAAAKLERTIERELLQRLREGAYGDQPLNVSEGIWKKVLRAMEREGEASRDKDMDTGIEDEEENEAEYEMDDEEDGAVEYVSDLDDSEEDLGDLDDWLGSEDDASQDDDSSEDEDDSEAEAPKKKSAAGDKRKRAAAPAARKPKKVARRRGEVEREVEFDRAKDLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V425</accession>
    <name>A0ABR1V425_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662671.1">
        <property type="nucleotide sequence ID" value="XM_066816979.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050039"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="578" mass="63213" checksum="DD622A70FEF5FEFA" modified="2025-10-08" version="1">MSESDLGKSKHGIPDVVMQHIDKYVDGLAPQIQPLISTELDVFQQKTVDSLEDKVIEAFRSLFDKSGEKHSDSRSLDGAPPDSYGIGSLPFANEIQSLTRSFSQITNDAQGDLQQILNLTEGGSNEPTRSRGGGHDDSFSEGARGFLSAAIGAVSEHARRESGGQPVALDGFLGVLSNAVKDSSRNPEEKARMISPEIKEKVSAILRQQHAPIAEQFTRIALDHIKKWLRGNTSSRDLGDGAKDEIKSLVKGVAGLFGHKKQSDDTSRDLPRDGEDSGGSGGGFSKMISDKLSTGIAQVHREVRLEFRKILGTIEKSLFEALPDQFQGPLEKILGGNPFDSSLDSQANASRGVGDRGLGDDIKTKLVESIRRLVRKVQETLREKILDIVNGGHRKFERSSWVFVQNKVEEKVQRFLPDVRITVPDDIGNEGVSVGAPDKGKLNNPPHEGGMPPAPSQGQPPPSHDYQPPQHDYKPPQHDYRPPQHDYQPPGQGYQPSNPPPTHDYRPQGSGGGYQPGQGQYTSGPQEHQYPPPPSQHNTYGSGPPSQSYPPPPPSYTPPPQSYPLKSYNQQQPPYDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4Q4</accession>
    <name>A0ABR1V4Q4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrophobic surface binding protein A-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662911.1">
        <property type="nucleotide sequence ID" value="XM_066817219.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050279"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046109917" evidence="2">
        <location>
            <begin position="21"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="780" mass="81818" checksum="05EAC0BE98289110" modified="2025-10-08" version="1">MRASTFFSFLALAAAGNTHSVEMHPHRSILQARTFTKVNSCMDKISAAVSQLADSTGAFVGDAAAIQSDTQHLVQTIQSCTASMDKTQMSAQDALSLSPLIGNLGTGCQSLVDNFQKKKLEFEQSKLCTVLQTGVDSIGKEAQKLVDGLVGKCPNESKSTTQTVGNVLNSILKKGLDLVNTFHCTPGASTSIAATKSKAVSSVATESKAKETKTTATASESKAVHTTTTSESKAEHTTTKAGSKEGDIVKTIIHTETVKVTEKVTEKVKETVPVKVTEHIKETLAVNATVPIKVTEKVKETVPVKVTEHIKETVRVNATIPVKVTEKVTEKVKETMKVTDHIKQTIAVNATIPVKVTQKVTEKVKETIPVKVTEKVKQTVAVNATIPIKVTQKITEKVKETIPVKVTETVKQTNAINATLPITVTKKVEETMTAKITEKVTEKVKQTIPVKVTEKITQTIGWNTTQMVVTHTIAEKVTETVKQTVPVKVTERIHETVGSNNTQIVHVTETKKVLHTVVHTVPVKVTETAKVTVTENNGGMVVHDTKTVVEHVTVTSHVVMEKPITHTLVETKTLVHTVVGSCAAAPAVTLTHTVIQSQAGVAPPPVTVTHTVVESHPGMAPPPAVTHTVIETHPGMAPPPVTLTHTVVQSHAGVVPPSETVTVKEPMAAPPQTMTVTAPCSAAPPSDTAIRAPPAAPSTVIAPPAPPAVTTPSSAASLAPVVTMPPPFAVTGGANSTSTAGTGGIFPTGQPIVTAGAAKPAVGSSALGAGVVMVAALLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V564</accession>
    <name>A0ABR1V564_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663083.1">
        <property type="nucleotide sequence ID" value="XM_066817391.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050451"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF150">
        <property type="entry name" value="OXIDOREDUCTASE TDA3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="464" mass="49822" checksum="B7D70603E6561D18" modified="2025-10-08" version="1">MDPNPHRPRNIIIIGGGIVGCTTAYYLSRHPSFNPAFHRITLLEASSIAAGASGKAGGLLGLWAYPQSIVPLSYHLHADLAAEHGGAERWGYRTVGCGQVAATLKHKDLDGTRCRQQNGHSNGAQPINRSTDSQSDSNSPVPKLENSDGILGPLPGARQPDNDLGKEWEKLPKQDKAATQLLTKSVLPTDLDWVDSNLIKEYAEMGQPGFTETAQFTTQIAALAEEKGVVIRTNARVTKISLTLGKTNVDSVQYHDGESGKLKTIHGVSDVVVAAGPWSGKLIPNAKIEGLRVHSVIFGADVSPYAVFTKIHLPINWVPPHRAAKGQKRRHKCEVDPEIYARPGGEPDSTIPLPEAADQAECDEAQCDDLISYIGTVSSTLGSAPILAKQSCYIPRHMRFGEERSPLVGGTSVSGLWIAAGHTCWGIQNGPATGKLMSEYIFDGAPKSADIDDLDPRQYKVGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5D0</accession>
    <name>A0ABR1V5D0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Malic acid transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013154</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663160.1">
        <property type="nucleotide sequence ID" value="XM_066817468.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050528"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09317">
        <property type="entry name" value="TDT_Mae1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030185">
        <property type="entry name" value="Mae1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162:SF0">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="47149" checksum="67A309F978425192" modified="2025-10-08" version="1">MWRRRNEQDDSPNDSDDTRNEELERVRKVRFLDRLEHFTWANFTFPMSTGGISLLLAQQTQPFNFRGLQTIGKVFYIFDLVVFSFITTCMVTRFLRFPGSLKKSITNPTEGLFLATAQLSTASIIVGMARYGIPECGPWLIVVFRVLFWIYFAVGWLIAVGQYTMLFTSPKLKAADMTPAWDLPIFPFMLSGTIASAGAGHQPPEHAVPMIVAGVTAQGLGMLISLCMYALYCRRMIEFGFPATQSRPGMFIAVGPPAFTALALIGMAKNFPTAQGYWGDAEMTVQILKVLATVTGIFIWSLSLWFWSISTLACLQVWRELKFSLTWWAFVFPNVGFTIATITIGESLESTAVEWVGAIMTILLIATWMFVFFHYVRAIVRNTIWVAAGKDEDFSDNHNHELSKMAKIAKEFDEEKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V657</accession>
    <name>A0ABR1V657_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Orsellinic acid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_013431</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663437.1">
        <property type="nucleotide sequence ID" value="XM_066817745.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050805"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF21">
        <property type="entry name" value="NON-REDUCING POLYKETIDE SYNTHASE AUSA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="380"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="1131"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1486"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1131"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1286"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1564"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1577"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="1163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1841" mass="199332" checksum="FAABAEE7B7434FAC" modified="2025-10-08" version="1">MAAFRDRYVLLFGGQGSSTIFSDTASTTVESDTRTSSAANILLSRCHAAFLQEIRSLDERSQSQLGIDLDLFAGPLALLKPATQYHSHAIIQATTIYLCQVLHYLAEVEHMNVTFEGFFDQIQETAGFSSGLIPAAVASRSRTLDDFVTTAVEGFRLAFWIACRTFLFGSELEKKQNTGDSAAPEATASLVIRGFSADQVEYRLAQHYATRTADVSLPSSRQLQVSVVTSSNVTSVSGPRADLAVFRSQAVPDLPTTFAHVLGDVRRQAIVFSESSGSAKPILSSLDGTLYDASQAGLSEWLVRHLLVHCVHWDKATSQITLSAREALGQGRIRAIKLLSFGPGSESLFPELQPFEPRVELVDFSPFKPRKSTRSYLESPDSIAIVGMSVNLPRGKGPDELWETLSQGLSAVEEIPETRFKVSDYYSEEPHKPRSMSARHGAFIRDPFTFDNAFFNISPREAMSMDPQQRVLLHAAQEALDDAGYVPDSTPSFQRASMGCYVGVATGDYTDNLPGGVNVISSPDMYLGLDRGHFLSSTGGCKPFDASADGYCRAEGCVLFVLKRLSDAVAEGDRIHGVIRGIEMNQSGNAHSITHPHSPTQIDLFQRLLQKTNVDPGSVGVIEAHGTGTQIESLRAVFGPQHSTRNPLVISSIKGNIGHCEAASGAAGLAKLLLMMRERTIPVQAGFKNVNPKFADLESSGFIIPRSTTAWTHLHKTPRRAVLNNFGAAGSNTSLLLEDSLGGLRDGLQMSSVRNSTPVPKASVTTFVFSGQGGIYQGMGAELIHTSPVFKDTVMTCEGILQELGFPSILSMFRDSETNSVPLNAVDAIIPSQCACIVLEYALARMFMSWGIIPDYVMGHSLGEYAALCISGVLTLETTLRMVATRAKLMVDHCVPDATGMLACNLSLESAESMISETHETSGMNVACSNSPSDCVVGGPLDQLEAFQKEFKARRIKSKLLDVPYAFHSPAMEPMMEPLRELGRSVQFSKPTIPVMSNVHGRFPCGSVMGLEPWSRGVSLEGAVFLEIGPQPTTLPMLRNTFASSSATYLSTLHKGQAAWKSLSSALAELAQRKISVDWRAVNNGSSAKMTSVPGHVLEGSSYLIPYREPFQGASDPQEGEPADTRRESGFPLLPWLNTEASSHSQSVLETTLAVLGPLITGHDVGGSPICPASVFHELALEGAHTALEPLDGQDLVVSNMSFESPLIYSPTRDTDIVTVHITRVGSIAEADFKITSHAVQGDQPTAHCTGHITIKSRSERLHWRRDAALVARQRQYFSGGGNDDVSTFRTKVLYETIFTRVVKYSAEYQSLAYLKVAGSNHEGIGSFKLPSDLIGRNCIADPVFTDTLLHAAGFIANLAVNSDEVSICARVESVEVEYRDIDYDSSFTVYCSLLDMKGMILADATALNAAGEVVAVVRAYAVTKVHCQPIASPGSHIAKHKSNHVPAEEAAAAPTCSNWSHHSLSTGDAPNSPVESVTCGTLLAQGISQTLNGIVMEVGGFSERDMDYGKSLDELGIDSLMQIEIVSKLTRAFPSQAGLDHHALSECDTLRALEARLSSMLQGPVQEPPALPNPGISDSFSSPNSLKVTPSHSSPIADARESLATLHIADGIQVPLCLFHDGSGQISMYSRLQGHDRSIYAFSDPYFGSHERPFHNISHMAKSYISQFSKLDHSPIILSGWSFGGVVAFEAARQLMADGFDVRGLILIDSPSPIDHEPLPNEVISQVIGGNVALKEEFQFNASLLGDYRPTPLLSNSQTRLKTVMLRSEELFDTEILCGVQYEWLSSQVSRDAAVAAWEGLVGERVEVMPIPGNHFEPFSNSNIRKTGAQIWRACQYIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6A1</accession>
    <name>A0ABR1V6A1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663466.1">
        <property type="nucleotide sequence ID" value="XM_066817774.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050834"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="424" mass="47508" checksum="A0EB694015742E68" modified="2025-10-08" version="1">MRSRPDPRSNPSFFAPNPDPLAAADDEGAFEYVGPDSFPDPPRSTFEDEYDSADSRHHRSRRHRSSRPRHRSRRASSLPPPPAYSSRPSSPTMSRRTDSPPPRRSKSHRHSAPAYDDSEDDVKPGKEDKWASVKTAGRRGFSKLGRVASTYAAAQMAGGKAKSTDRERSRSRDTYDDRRSHRRSRRYSPSPSPSPSPPRRRGTARHSRRDRPPINGRKKSYSVSPPPLSRDPYDRDRGRGRGGGRDRSRRRRARSPSYSDSSRSSSVDSRYARRRGGHRRGRSEGDYDDDRKRRDRRSSTAGTSRRRDKSSMGDKYREHMRAPKPEIADRWQMAARAALEAGGVTAFRLRKQPGTWGEKLPKIATAAMGAAAIDAFIDKDPRRQKHGGGGGMKGMAESVIGGMIASKVMGFKSATTHKGTPRYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6K2</accession>
    <name>A0ABR1V6K2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662351.1">
        <property type="nucleotide sequence ID" value="XM_066816659.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049719"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="689" mass="74544" checksum="CC25AB8C77AF261F" modified="2025-10-08" version="1">MGGGGGGSTRAKSDISSNTPAVVAVDHQHYYRRHHAPDRVSEPSSVQTVAAPASSLIGSNAYRKPLISQYNKAPFSSTQTQSSTKATGIRRPGLRHRATTPPLVADHHHGQTEHSPRSTRRSPSESDHRELQPGCSRSGAIRRGPRSPRSPREASPPNFSRKTTPSPPNGRSQSGSETGDVSTKVRETEKEDTVSSQGGEYTLQAKTYQPPDHSTTIVTSSIQPPKSHFSPSTASESSDNNLSTTSSITVKSWKSPDTTPSQTPVEAHFTLPATKYESSSSSNHGPRERPSNPSLELSLNKELPLLPATTYQPVAPKVAEATGQKKPQKMPPVPNHRDQEIKPLPATVATCNTKILGPKPIGELYKRRQKTGTSGESATSATAVSRVPPAADDTTIPVREKKGAAVPSSSGSIAARVGLQPLSTQGSKESHLRSQSPYPRHRSPHGSSDRSVRSESSSAPPRKASIGTMYFTMTFSPTSKQAELKDILPPAQVVAENLAKPVMPKGQGDLEAKADHTREDVEREMQMLIQEVDSAFRAFGTARSRRAQRSGSGHRAVDTAPATAKGDIKTPSRLPPHREEERRHSLSVEHLNLSKESNESKASNDMPRQPPSTPRDTTNKSTQERGIALSRTSRKDMPPTPPPSCRTSNQSESSRAGQNPPSKGGREEWKRFQATERHRDDVKYNGTAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7A0</accession>
    <name>A0ABR1V7A0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013564</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663570.1">
        <property type="nucleotide sequence ID" value="XM_066817878.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050938"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045363293" evidence="2">
        <location>
            <begin position="16"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="677" mass="70507" checksum="047265F247258643" modified="2025-10-08" version="1">MQGVLLLSLAASALAAPSHHKRQTATGKSCKAKDPVTEILKNLPDAGDFCSAFLGETPRSRISGDVTVFSTAYTTLSADPFTVTVQSTVTKDEEVITGVYDSAFSTVTSFVTGYLTNTIYSTVESIETEQSTAVSTAVVTITETGTQRVTDTVSLFNTKFVTDTKTEVVTDTVTNVVVEFVTLSFTNTDTATETSTIAATATDTTVETSLQTAVTTTYIYGGQTDVTTTTNTGTTTDNTITTTGYTSKTTQVVTQPTTTFTTVIPIKRSVVSSLAASVLSTPSALASVPADKLSSACSKLQTSSSSASAQTVYTTEVGSASTATVYVTEIYTDLVTTVNGVVSTVSGVVETVTVDTVGTTTALSVVTFHQPLTVTVTANPTTIVSGDVTNLATTYITTVVVVDVTATATETSQATTTATTIDFTLIEGTSTLVSTVLTTAKTTTDTTLAVTTATTGVVTDTTTTATTNTETTVQETSSTTLLRRHHHPACDQDGQRHPDPDRIANGHDHRRVDHDLPPNLIVHGGFEPTTDGVTPWTKTSNPFSGSGDYSYVTPGINSDRAVKLSTTSSLISMGKSVTISQTFATTKNAAYTLDFDLMPTQKGSSNTAFVCKFTSGSSTKTFTYTLGATNVVAHQTNGFTAGGSSTTMECTLSGSDKTGSGVVVDNFRFALPCGGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7P2</accession>
    <name>A0ABR1V7P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydroxybutyrate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013961</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663967.1">
        <property type="nucleotide sequence ID" value="XM_066818275.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051335"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8067214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="29904" checksum="79C67F749DCC4DF4" modified="2025-10-08" version="1">MISKKTVLITGCSNGGIGSTLARLFHQRGYHVFATVRDPSKMSHLSTELSSDSLTLLTLDVVKPPSSRSLNLLTGGKLDCLVNNAGRNHFMPILDEDLDVVKDLFQINFYGPLALTQAFAPLLIAAKGMAVYITTIFGYLNVPYMGTYAASKRSLEIVADTLRLELAPFGVDVLEVVTGGVKTQGQTYFGDFKLPVDSLYKSLEDIIAGRAQGKDGFPRIEAVDYATTVVDEIVKRTTGRIWCGNNADVVRSSTTATAVPQSAMDAGAVMGCGLDALGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7R2</accession>
    <name>A0ABR1V7R2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663979.1">
        <property type="nucleotide sequence ID" value="XM_066818287.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051347"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047128421" evidence="1">
        <location>
            <begin position="19"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="81" mass="8469" checksum="5262FB110756C8C3" modified="2025-10-08" version="1">MQLSLAILALVSAAVAKAIPRNDEPAIVAVPDAPGTPEMGTEATTHLYICVNADFTGACTNLAVNTGVCYERFPSRSFTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V854</accession>
    <name>A0ABR1V854_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663239.1">
        <property type="nucleotide sequence ID" value="XM_066817547.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050607"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="119" mass="13307" checksum="C34744C247D4CA91" modified="2025-10-08" version="1">MIVPARVHHGHLILHPKPLKARGAYQVPRRMGTGVSIAIQIQIDIRDRAAHFLQLRQAKQEIHVVLGEFIISQPQQYILRPQVPMAHAVLVQKPHALCDLSQQVAVRLGCVQLAEDRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9E4</accession>
    <name>A0ABR1V9E4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013637</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663643.1">
        <property type="nucleotide sequence ID" value="XM_066817951.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051011"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="100" mass="10737" checksum="B291F16F980BEAF8" modified="2025-10-08" version="1">MVDPDDGGLIQGTAIAIPDLVRPRYAVGPGRKRDIYTLCSAPKVEDEGKVVLEEALSVVVETVRLPIALAVVLRAAEHMTTLLSGLVVPGPEEYTERTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGS5</accession>
    <name>A0ABR1VGS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010622</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664227.1">
        <property type="nucleotide sequence ID" value="XM_066814937.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047997"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7025" evidence="2">
        <location>
            <begin position="635"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase lid" evidence="3">
        <location>
            <begin position="1049"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="957"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1149" mass="128094" checksum="EA55C641F8379338" modified="2025-10-08" version="1">MSDSPTSDTGATPALASRHRSLEPDIRTYLKPSRPGGLPSSWSTPLIPSRSRELPILDPNNGSLSPYRATAPHAPTPFIGTAPPFPVPGGLLMINKKPDEVRVRRFNDVLKRIEPPLIDHLLKWTIKRPRHNPTAIRLVMLGQSEADAKMYMVVFCEQRVRRRAKKFFSSSLALELCKPQGAPEHAIEVLVVDPPIPVARTVAQLPARNRGPKLSGMTVGHAIEELENPVPPVKVEDEQQDDSESEMASDSRDQGTNVPEAAPSTPSKDLMLLRSQRRENPWESNSVMLTALKAIPGPDTTAYYDWALVDIGDLARNSGVYNVPKTTGLRGVSSLMMPSSRRLESHEDSPVTLMSSEGPKDGTISFVPLRLLLSPGRTFIDTYMIKMYDPHVITHGDSGSWVINTKSGLVYGHLVATDVLGGGHVIPLLDTIDDMKDRLGATSVELADDAETRIPPRERAVSPSPRSSPEPPSIALGTRPDPNQRPSPRSAAASRGSSVRQLAPPDWNVVTRDHLDIEVFSTKRTSVFGPQADQGAEFSSIGKPDLIIHSRALVCALRSVIRYYPDSDLAASSPTFTWPYAELVHHYEDLKKYAEDSAPPGNDLRCRTKVYIIEHTQLLTQFLDTQIMPRVREELDRNKKGLFTFDMAWVSHKPGTTVVWNGNLPILPPQRSVRPDSPSYKLKPITSQGPFVIQDFMYGDRAGQAEVRLWSLEYDGQLLGKAEYYTYYRPFSGQREISWRVAGTASLNGGDFPQGDIDRIRQGKTYWNLVRQIQCRQYTAESAGVPRRAVDSLVMVDCREALKQQNLEGAQLLFPDERKDLANWAPGCSCPFCEVAKTEDNRPRKPEFADYVSDPKSKEELTDHQYFLCPSTIRGFDLNSQEWVELYVEHLATPKWDRSLVNTLVMDSRQKHRIMRLFEAHSRAKKANISAPKGKRIGLALLLHGPSGSGKTLTAGELTSGMDNEVGQNKTGDSEKPGADMTELFRLANAWGLIIHITDADLLYEPKPPRVQPCTGYESKLDNTGDTASRHLRRGCHLKNPRTGFYPLFSEDESKHVWNNLLAKFEALGIGFSYTAREFISSPKMKNRKWTGSEMRRILESAAAVAKPADWGDEGEDGEQAKPFVDVLDLEDVVELSDDFRLKFQQLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGX7</accession>
    <name>A0ABR1VGX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664272.1">
        <property type="nucleotide sequence ID" value="XM_066814982.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048042"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609:SF1">
        <property type="entry name" value="RFEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39609">
        <property type="entry name" value="RFEG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="380" mass="41641" checksum="2DEDCC27AB65077E" modified="2025-10-08" version="1" fragment="single">PDVQLSPPPASSNRQNEYFVPRDGIDREPTSVATLETMHSSGPVSTRYFLLVLRDPLFQLLIWVAAQSPQTGQVVQGYFITAYRNLTTAMIEDLKADSARWDQERRQQTARNPVGGTIASAGVYVQKSNSPVVQYRNSDTHQSRQYYGPTEGANQYSDASRDNYDAGAPRYPGTGSAGYNGASSNSGYPGSSPYAGQSGGYGQQAYTTGQPQFAQSPPRLVPEWCLHVRVRIYPSPLGRKAIRGSWRTPNRRAGQWRLWCQCCVHNRSPGESPSLPQPWFRVDQSISGAYYSQNPAPTPAGFSAAQPVDSFYGRASPAGAGAFASTHDSQYENAPPPRNSAQPPSTQAPSSGSSSRHNRDNRDSVDRHTDSRHRSHRSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH92</accession>
    <name>A0ABR1VH92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aspyridones efflux protein apdF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010778</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664383.1">
        <property type="nucleotide sequence ID" value="XM_066815093.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048153"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF130">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="284"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="378"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="25"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8070575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="480" mass="51109" checksum="EA904ECC7F48CE98" modified="2025-10-08" version="1" fragment="single">HLGASGCRPPVETAVVIRQIKFSLSEPGPLNSSPTGKFIPPASRAASALDTPPRYSSDSDDLEDFKSEKTTTPSQEESEHTLQAWLQVFASFLLLVNGYGYYSSFGAFQSHWQTTLQRSPADISWTGSLQLSLPFIGAISGRLMDQGYFRSLLVTGCLLQLVGIVVTSFVERPGQFAQLLLAQGMVQGLGNGILFTPCVTLVSLYFKRYRAFALGVSSCGAPVGGVIFTMIARELAFKIGHPWTIRVMGFVVLFNCAVILAIAKPKAIEKPLSAPWFDSESWKDATYVLFAVGIFFVGWGLNFASFFIASYGTNIIGLEPAESLLLLLIMNAVGVPGRLAPALLANLYCGSFNLLIPFAVGVGVALLGWMGVHSEPSYIAFVVLYGVCANAVQTLLPSALAGLTADPAKMGVRTGMAFTVLSIACLSGPPIAGALIALDGGQYRYAQTFGGLSVLGGACVLGVARWLQARSSRTTAQDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHH4</accession>
    <name>A0ABR1VHH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010853</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664458.1">
        <property type="nucleotide sequence ID" value="XM_066815168.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048228"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF164">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="451"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8070650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="56300" checksum="FB87D76F8607D461" modified="2025-10-08" version="1" fragment="single">MGESVSTIPGFHLAFVEKSSWLSVRRVERARSTPPSPNMSDTKMEEGRTETVENIKERREHTHDHATGTVQLIDAKHVVLIPTPSRDPYDPLNLPEWRKNLIVLIIGMYSAFAVLATSGMGAIAPVVTAMYPHDDPARVTDLLTYPTLFMGIGNLFAMPLSDAVGRRPVFLGSLALSIVAGVWCACSGSSLKSHIAARDILSMAAGQSEALTALMVQEVSFVHQRATKGTWNAAIQGSVCGAMFVATTYLVPAWGLKWWYGIITIVNAIILIFAFIFVPETLYLRVVEEYDGETHEAASTSDGAKVERVTTTANHTVDYARYGPRTWRRDLRIFALPAPRWDKMATLYRDAARGFTVPTIVWLLVLNGAFLGVYVFQSSTFAGILLAPPFGLASEWLGFVQMALIVANLVALPVPEFRLLTGILPAAAAVVSCVIFGQTGAHPDTPQWSSWAGIAVPYAVGYAAFLGANTVGITYVLDSWPREAGALLLVVAAGRGFISFGLGYATVPSVDRLGYDGAMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHS5</accession>
    <name>A0ABR1VHS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664240.1">
        <property type="nucleotide sequence ID" value="XM_066814950.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048010"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF13">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="222"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="661" mass="73003" checksum="7535117D6C121F77" modified="2025-10-08" version="1">MGNTVSSTPSFRSCGLCYFKLPAGTPFLDQPRVSRRGIELVGLPDQGWKTGRLDDVLLPWKNIDYVEMETELDALRDSSGRGCVGCTAILQCLDAQLRDRGFTLGDQCWQDQCTLIWLVGDRKPYNPSLLLRVSVSATTKNQSEEHRVEEFSVSPSAAALGYTGSSASLEAIKTWLKNCKTAHEDCRQPAGVLPYRVVELSRDANGQADFRLVQGLGGREKYACLSHRWGPSTERCRTTSLTLTSYLERVPPDILPKTFREAGEVAMYLGLKYLWIDSLCIIQDDEDDWKAQAAEMCNIYQGSYITIAATSATQGDDGLFHTVPKFPVSPVESADRRDLVLADFPLLARGWVYQELLLSPRFVHFARDEAAWECAGGNGDCECGMAAGQALWPRKRAYRINMAAAPALYYTSAGWRQMASEYSTMRLTYDSDSLPAIAGVARQYGTKHRGSLGCYLAGLWEKSLVQDLLWYVPSEVKSARREASPVPSWSWASVTGGSQQLGSLQATTAVDPLELVSFRVDLAGPDEFGPIKYAEITVRGLLALGSWTAVPGSASGHRFAQYHPCRIISTGSSGRTGGGYCIDADYDFLDAEGSRRLEEGCTVFCLKTGFVFYQHHVCLILRPLNEERTAFERIGLLQTAHKDDVDSWYEGGQAAQAFKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJM8</accession>
    <name>A0ABR1VJM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Manganese lipoxygenase</fullName>
            <ecNumber evidence="3">1.13.11.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_011295</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(9Z,12Z)-octadecadienoate + O2 = (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate</text>
            <dbReference type="Rhea" id="RHEA:18993"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30245"/>
            <dbReference type="ChEBI" id="CHEBI:57467"/>
            <dbReference type="EC" id="1.13.11.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.45" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664900.1">
        <property type="nucleotide sequence ID" value="XM_066815610.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048670"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.245.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000907">
        <property type="entry name" value="LipOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013819">
        <property type="entry name" value="LipOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11771">
        <property type="entry name" value="LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00305">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="Lipoxigenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51393">
        <property type="entry name" value="LIPOXYGENASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoxygenase" evidence="10">
        <location>
            <begin position="262"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8071092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="739" mass="84255" checksum="09048BE3F148E015" modified="2025-10-08" version="1">MGSTLSTLRRQQRPPKDHGIIGELDSRLPKPSPEHCLLDPRKLLRQPDEKDVLKNIVPIRHAPLQEFDAGVLSEELLNLKIFDIIDHAALSGPNSTKYAGGNIKEGTYAGTQAALTQIYSRIERSYESYFDVLALEPTLPRYIDLSEKRNMYQWSSYPTEEDGKPSGFPPHLQTIPKADDVSLWKIFNNLGILESQIIVQKVIPDTFLGKTADWILGKVRCVIEGTPEKGVTIKDVEEYNKWHRKSGTDIARGENIGHLDDWFSDRRFADQSLTGTNPTTITRASPGLIKEFVEAARANGYGKWAETLPKIDPASLLVQDCSYFREAFGVGADEVLHHKQPASDDNWGCAAVTLYRLHPDGKIHPIAIVIDYKGTMAKSVTIFNKRMSPSDSTKGEATDWPWRYAKTCAQVSDWFRHEISVHLTNSHFIEEAIIVATNRTIPMEHIVYKLLHPHWYKTLSLNAAGRASLVPQIMYDVVGASPEQASNYLRYAFEHFDFQGNYVPSQLRDRGFPSDPTGLEDPKYKNYPYAKNMTLMWTVIRKYVCSMLLTYYDQLRADQMVAEDPYIADWCREVQESGHIKTFPTIKTFDQLVDAVTMCIHLAAPFHTAVNYLQNFYQAFVAAKPSCLCSPPPATLADLQQYTERDLVAALPINRQRQWMLESIVPWLLSFKVGTDRSLLNFALSQWSVYRRKTEPKEVEIRDVSEMFYLDLCRLAKLFYYNSKAMDEGLFLTWSWIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJQ1</accession>
    <name>A0ABR1VJQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665253.1">
        <property type="nucleotide sequence ID" value="XM_066815963.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049023"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="44831" checksum="CACCE399BD79F350" modified="2025-10-08" version="1">MDRLPREILAEVLEFLVGPAPTEYRLHDQPSDGLLESEVLDLKSASQVNKLWRGQALPILFRHVQWRPELSSLDGLDPVPLLRFLVGNRLQRNVITFTLLVDFADHQIESARVAYQIRPSDLEWLWDQLFAAIDPLRFTIIAPPATLAAFLNRMLFLDDAWSFNIPYHILSLARSHRGPRRDSENMLDLSSSPFGTSSSPPGASSSVAGSFKEQENTPTTPPLFPRTVVDFNYIAIFPLSSHISHLIHHLPKLDRFFVRFTPRPNNCILEDRQTLKQVDIADLWMERTTAFRHMLGEIVNDPGGGGGGSGSENWKTLNVFEIGEMEDAEVRALAHTYVDRAGSGWIVTDGVTPGAMVRVDEEGKPKGPSGAVVPHTPAVRHDVLHGPGWAVIPNYHFQPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKJ2</accession>
    <name>A0ABR1VKJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664629.1">
        <property type="nucleotide sequence ID" value="XM_066815339.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048399"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="341" mass="36848" checksum="F345BA06DDEDA5AB" modified="2025-10-08" version="1">MLRPLDDTDDATVDTPTDSPIIPDSPRSVRSRPIAIELPVPRKITSSSSSVYTPPAPLSARGDVPGAYFPFHEEQNRVYHGHPFHLDASKARQRSIQKASLSRSPEQQPESAPSVTGRVPPPTVAPMSSTRPDSASSAPPPSMSSTGSVNTPVASYIPSGVHASPLPMGKYYPSNYEKRKEEKRMQQPQPRPMATNTQSMSVKSDSHVPMYRPDGPSPMGHSRNESEAKRRLQQYQRDMIAQATLALNGGNVNAAALNAISLRNMGFTSVTKPNKPRLEPLGSPGPVTPMELESSDDGYIGARVASSGDSAHIEEIARAIRADEERKRREGTTSPVVELSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKU9</accession>
    <name>A0ABR1VKU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664658.1">
        <property type="nucleotide sequence ID" value="XM_066815368.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048428"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="459" mass="50297" checksum="ACE5A3E3BA73ED20" modified="2025-10-08" version="1">MDTSKQPQQNTQVYTTVGSIYNPSAAPLQPPTRRGRPVKWPPHNELTTKSSLSGLSLAHQTRSPSNAATAGNLLHYSPLQQNSERAVSPITSASDSFARMSFTGSLSAHEPAESHVSREQDDDEDDAGEAAEKLKVMSVKTLTNLASYPNPMQKQAQKVLSRARPTANTLVPLRGARSDPVSVAGLLQSDGTSEYPSKSMTRPMFDSILSNGPGAPQPLTAGPPGPRRFRSSANDQSSGQVASAYQQPQAQVGGIVTSQVASHRRSKPWGNDKSTPPPRNDTAVSVKSVLNAGASVKAALKETERRKITDTLTAVEAAKYYPHSLPSDFDYSTKGIAPEWQHGYPLNRFGQPKTRSETHRAKIHEIWYAGSDMMSKTVTEARLEKNRKDLERTIGIQSESLRKDRTNYSKITVDEANRLPASEHSVPLISMAYQTLLNHPEFNKNSKLPRFPAFPTYKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VMB0</accession>
    <name>A0ABR1VMB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Asp/Glu/hydantoin racemase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HyuE racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665244.1">
        <property type="nucleotide sequence ID" value="XM_066815954.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049014"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052186">
        <property type="entry name" value="Hydantoin_racemase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053714">
        <property type="entry name" value="Iso_Racemase_Enz_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047:SF5">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="15924" checksum="99D2849C7452E00E" modified="2025-10-08" version="1">MSLTSRARGERWGIVTTGKFWEEHLSSGVAQYLRGAHSLGPGSTFAGVESTGLNASDFHHGVDPAVITTKIQEATLRLLDKGVSCIVMGCAGMAGLEATIRSAATERNGERWAYETLHVVDGVRAGLVQVDQMIKNFRLRRQPGRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTI4</accession>
    <name>A0ABR1VTI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="1">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_009206</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665483.1">
        <property type="nucleotide sequence ID" value="XM_066813521.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046581"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012066">
        <property type="entry name" value="Met1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028162">
        <property type="entry name" value="Met8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050161">
        <property type="entry name" value="Siro_Cobalamin_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028281">
        <property type="entry name" value="Sirohaem_synthase_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790">
        <property type="entry name" value="SIROHEME SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790:SF6">
        <property type="entry name" value="UROPORPHYRINOGEN-III C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13241">
        <property type="entry name" value="NAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14823">
        <property type="entry name" value="Sirohm_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14824">
        <property type="entry name" value="Sirohm_synth_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036555">
        <property type="entry name" value="SUMT_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75615">
        <property type="entry name" value="Siroheme synthase middle domains-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Siroheme synthase central" evidence="11">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Siroheme biosynthesis protein Met8 C-terminal" evidence="10">
        <location>
            <begin position="215"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="9">
        <location>
            <begin position="278"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="469"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="469"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="480"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8074543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="584" mass="62558" checksum="A40D2A43A63C7687" modified="2025-10-08" version="1">MASHISMLTTTDARSHVHLIVGSNPLAASRCAQSFNVGACPLLVAPAAAELHYALQKRVDAGEVKWVKKSFEENDALTLGREELGGIVDAVFVTSGPRDPQSAQISSFCKRNRIPVNVVDATQLSSFSLLSTHTDGPLQIGVTTNGRGCKLASRIRREIAASLPQDLGAACSRLGDARRRIQEEDHLLHSALADGGDLDDSLDQTATFNKLVREADLDAAKNRRMRWLSQICEYWPLKRLAAVSDEDVAGILKSYEGVNAPESIGRPTAKSDPSARGRVILAGSGPGHPDLLTQATHKAIQTADLILADKLVPAGVLDLIPRRTPVHIARKFPGNADAAQEELQEMAIAGVREGKAVLRLKQGDPYIYGRGGEEVAYFRRHGLGDRVTVLPGITSALSAPLFSGIPATQRDVSDQVLICTGTGKKGKPPNPPEYVATRTVVFLMALHRIAALVGELTEHTDAEKGIVKEVASGEEKPESSETQEPSTTTNTPPKRTLWPRNTPCAVIERASCPDQRVIRTTLDRVVEAIEQEGSRPPGLLVVGGACEALYKSEKGRSWVVEDGFAGLEIGDQLDLAGSLGPISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTX1</accession>
    <name>A0ABR1VTX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665638.1">
        <property type="nucleotide sequence ID" value="XM_066813676.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046736"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040200">
        <property type="entry name" value="Mug57-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28156">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN YDR262W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28156:SF1">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN YDR262W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="18675" checksum="A0EB77F440450464" modified="2025-10-08" version="1">MASSSDQPRMQQNNVMLSDVMSRDRSINIFASLTRDVASIEQRLEDPSQNSTVLAPLNSQIDALPRKPWEDAQDYETFGAAAAYEGDEGRDRAQKNLKKFAEAHILPLSPWQEGEKVKSLLAGDKEIWWENKDGKKVIYPDGIEVDSIAGKVGNGELWTLKGVRNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUA9</accession>
    <name>A0ABR1VUA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009491</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665768.1">
        <property type="nucleotide sequence ID" value="XM_066813806.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046866"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF13">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="362"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="505"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="395"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8074828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="545" mass="60644" checksum="80BF1A48A641CA17" modified="2025-10-08" version="1">MDHRAQPVSCHVCQRRHHPQRLPFYCAVDARNMLYESRIENAKALMETAMLDGQISALELGSDPEPATSTPIRATRRYVDQCVSATEQARDETEHIIATAERLQQDIDKAKKEIETRKAKIARRKADLATVSQGIAARRNRELEEVKKAIKMTRYSWDREYEAMTQYRAALCTEVAKIYRLQRVRRSNPIRFEYKIGGIEIVNLHHMNSTSPEHISASLGHVAHLLWLAAHYLDIRLPAEITLPHNDYPRPTIFSLVSSYHHGQVPFPGSSQLPNDPRDRGYSHIPHPRPLFLDKPLSTLAKEDSPTYTACTEGACLLAYDIVWLCRTQGIPVGDNSNNFEDFSCMGRNLYNLLIGSSLQRNQPGQQLIPDPDSTSSPGRRGSSTADNNNSSNNEIDPTSNNDLINKTAPRMGQWSHGTAHTYLGGAAGHDFTKYFKLPNPLKLADQLRARLVNEAPAPEWELIEDDEFGPNDLDDGVLIGGTPRSRAKPGPQQRFGLESYMSVNTVKGGGGGSDASPRGPGAVGGVSGKDREKSTNGWTKIKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUL3</accession>
    <name>A0ABR1VUL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665874.1">
        <property type="nucleotide sequence ID" value="XM_066813912.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046972"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037470">
        <property type="entry name" value="IVY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38407">
        <property type="entry name" value="PROTEIN IVY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38407:SF1">
        <property type="entry name" value="PROTEIN IVY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="491" mass="52784" checksum="74C7406DC59AD0A7" modified="2025-10-08" version="1">MATPVNDRPPSPSPSQLPIPSSPTFTYASTANVLSSYTLPLPPPPRPPHAILTKADLEASQTAYADLLSTAKAYRQALATLSTTASAFGASLEACARLKESRAEALGPLPGLGGGGGGGGPSLSNSYTAHKQGSCTADLLLGASGVHHLVANHQQILSETVYRSFEVPLLHELDKWRAAIDDEDERYRREAAARSQEIRRLEKEGLKLHKQRRRDVSKFREHLVELTSRLDGLTALHGDHARTLLRESQETSVKILDASCSLVRAEVDIFESLARKGWSGGGLDELLEKGRDLFASEDDALVGAGIVGTAGAHNGVDGAKLFSILPPRSILQQGDSGVRFGTGGSGKPRGHGRADSLLVDTDRYQSLTGAVDRERGDNESIFSDFNQSRGVRPFSPQPIRRNHTDVMLDPDSLFLGDDEGEGARDVTAQSLTLERQRDSEEEESEEDGASPWKDEGLRNASGGAHSPGSTVKGRSRRWSASDKDENSSERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX79</accession>
    <name>A0ABR1VX79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin-related protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665690.1">
        <property type="nucleotide sequence ID" value="XM_066813728.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046788"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13395">
        <property type="entry name" value="ASKHA_NBD_Arp4_ACTL6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="477" mass="52604" checksum="1335C32913DF5E9B" modified="2025-10-08" version="1">MAQPLTTASVPTDIYGGDEVSALVLDAGYCSTRAGFAGEDVPKSVLPSFYGSIKDTNAASGSRNVFGEDYLFARPDFEIKNYMSRTESVVEDWDTAVQVWESMLLDRLQPERRQTQPSKNGLNDGADGEGDVSMEDAAISAENAENAEKPLAESPLLMTEAPWNQGKAREKAIEIAMENWGCPAFWLSRTPVCTAFAAGKASALVVDVGGANTSVTAVHDGMILKRSIQKSHVGGIWLSNQIRSMFDSNDPKIEVRPSYMIESKVPVDAGAPSQAVLRKLNYELHPSYRAYEDERLLTEYKESVVEVWRGPGRYSNPGNEDLVKTQPGRIFEMPDGSNQMWREQRFRVSEGMWDETAQLPTASEEERITKAQTVPELIRACLNAVDVDLRPNLLGNIVVTGGTSLLNGFNDRLNNELMAMYPGMRVKLHAAGLTTERRFGAWIGGSILASLGTFHQMWISKKEYDENGAGIVEKRCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYU9</accession>
    <name>A0ABR1VYU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009696</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665973.1">
        <property type="nucleotide sequence ID" value="XM_066814011.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047071"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF43">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="47"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="515"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="548" mass="59017" checksum="8BE307F32D4F86C6" modified="2025-10-08" version="1">MASRYHDTGTMPTLGRTDSMEEALNSSSTNRGHLYGQSMSPLRQTTLVAILLLGLLFSSLDASIVSTSLVTISLDLKDFITVPWVALSYLLAYLGFAVAFSKLSDIYGRRALVEISWLLFGAFSLGCGLAQNMTQLIVCRAFQGIGGSGLYSLAQIGLFEVGPTHKPGLLGALIGMTLAVSIPFSTVALAGIMLAWPSRYGSRSSMAETYKRLDLPGIFLVIGGSTLLVFSLQQAGSFSMSWDSPVIVATLTIAALCWIVFVAWEYLLETKHYMGIQPLFSSKLVTMRSYMAALVFMVLTGFNYLAIIIILPERFQIINEQDSLMSGIHLLPMLGACAFGSFLAGAISSKRNNTSPTLIAAACLQLIGVGLLSTFSDVDSAIQPQYGYQAIFGLGVGLTFAAATMLASLHVDHENLAVAQGAIAQARVFGGAIGIAVCSMVFNHGVKHKLVDHLPPDDLQALQQSPVIGALFSPENQKLVRRVYADAFVNDIKIFIYLAAAGVIASLFTFQRHPPPMPGVQRSNKEESETPRGALSETELEDMSRHRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZ46</accession>
    <name>A0ABR1VZ46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Histidinol dehydrogenase</fullName>
            <shortName evidence="7">HDH</shortName>
            <ecNumber evidence="7">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009862</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 8">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666139.1">
        <property type="nucleotide sequence ID" value="XM_066814177.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047237"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF2">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS TRIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="410" mass="43667" checksum="E9B48F4B8C2DB755" modified="2025-10-08" version="1">MGTAQVTEALKRPSQKSAEAIMGIVHPIINDVRQNGDKALLSYTHKFEKATSLTSPAIDVSFENIRKFHEAQKEEPLKVETMPGVICSRFSRPIERVGLYVPGGTAVLPSTALMLGVPAMVAGCQKIVLASPPRSDGSITPEIVYVAHKVGAESIVLAGGAQAVAALAYGTESVTKVDKIYGPGNQFVTAGKMYVSNDTNAGVGIDMPAGPSEVLVIADSEANPAFVASDLLSQAEHGVDSQVVLIAIDLDEQQLQAIEDELHKQAMALPRVDIVRGAISHSVTIQVKDIDEAMVISNDYAPEHLILQLKDAEKVVDKVMNAGSVFIGQWTPESVGDYSAGVNHSLPTYGYAKQYSGVNLGSFLKHITSSNLTADGLRNVGSAVMQLAKVEELEAHRRAVEIRLSSMDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZ60</accession>
    <name>A0ABR1VZ60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">IQ calmodulin-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009877</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666154.1">
        <property type="nucleotide sequence ID" value="XM_066814192.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047252"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044159">
        <property type="entry name" value="IQM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31250">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN IQM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31250:SF27">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN IQM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="240"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="448"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="661"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="661"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8075214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="713" mass="79750" checksum="ACC0A377D0E2DCAB" modified="2025-10-08" version="1">MTDISPQPRIYEYEAGEPTATAASQPFDTKTPPPEPRPAPALEGSQRPLTPPLESRGRLHQEPKSKAPSLSPGTTASPRSARSHQEYLDSLQPPSGDEVQRLAELQDQRARERKQHTRDLRHKSADIAKTEASAQRDFMESRQHHCIQSTLKQAQTRSSHESSSSSSGPRSAASAAAVAAPPVEGVDAATAAADNNALDSLQDKAATLIQRSYRGYRVRREMKGLGLDASTRWTHAIRDAKWQNLTKPRPRGSGTTSPDDNDGEGTAGDAGIRPRSSTSAARQNWKKVAAIAMRANGDEDSSHSASESESSSDLEMNENMTEKEKEKMRKRRAKAQAKRRKKAKMMGLQYFLEMVDVKHRYGSNLRQYHAEWKKADTNENFFYWLDYGEGKNFEIEGCPRDRLEREQVRYLSREERQHYLVKVNSEGRLCWAKNGLRLDTTEEWKDSVDGIVPVDDPTPAYAPDIESHSQQHHDPARHPEDHDSTSGSDEESDASESELEAARAAKYATPTLDDAKGVKKIKHVSAATIFQRLLRKSVKKNTWIFVADTSFRLYVGIKSSGAFQHSSFLQGSRISAAGLIKIKNGRLSSLSPLSGHYRPPAANFRAFVHSLRDEGVDMSHVSISKSYAVLVGLEAYVKTRRKGKDAVHKATLHRDRILDPEEVARREEAERDKSESAAKERQFLQKEEEEKRGASRGGGMRLLQRLGFRKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W132</accession>
    <name>A0ABR1W132_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666768.1">
        <property type="nucleotide sequence ID" value="XM_066814806.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047866"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="185" mass="20171" checksum="28409D6892696EFD" modified="2025-10-08" version="1">MEPALFGLLGLCFAWPFLDTPTGGNIWDEMHRSDGDQKSKLPTGGDPISRFARPTLPVTSHAAASEGPSRVPVLGEDEQLGLIQGSVILFPDHLSGNSVPKSGVVQGVQSAIGISYGYGMPCDKAIPKFTSQGTPTLTLPIHCRLLWEITRSRGMWVDCRRYNDHSFTHYHKHGGSQDKQIMALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7A9</accession>
    <name>A0ABR1W7A9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007199</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666856.1">
        <property type="nucleotide sequence ID" value="XM_066811514.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044574"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="301" mass="33806" checksum="03C4DAC9E9D7E542" modified="2025-10-08" version="1">MSNYPSDLHRTTFDTPTTNATAWLDATLGSVVPAQCHSHNDYWRDYPLFSGLAAGCTGTEADVYLSDDGRDLLVGHKRASTSAEKTLRSMYLEPLFQMLQHRNSGNVSRSADAQAQGIFKTDPSEPLVLLIDVKEKPDIIWPIVLRQLEPFRRSQFLTRYEATAGVDEPGQIVPGPLTVVGSGELDLESLATIGQVLFGFSRHQMEKLRDQIRSAKERGLVVRYWGVPGWPLNYRDYIWMTLRDEGVKVLNVDEVKEVSAPWTSGYLKCVVAMIVISCCAVLFFTIGAFIQYRRVRSVTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7I2</accession>
    <name>A0ABR1W7I2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666911.1">
        <property type="nucleotide sequence ID" value="XM_066811569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044629"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF1">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="86"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="567"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="638" mass="71582" checksum="76436AF35ECEE49B" modified="2025-10-08" version="1">MLYGNNLKERAIHLIEAPEGSCVEMSGRCLDKDWVDLGLLQKWNTECLQKHGQTCFNPLKIPQVYPAWLIDTYNDCLVPGDGIPDFVTLSYVWGAGKSLCTERANVEDLQQHGALTKSPISPVILHAMGLIRALEERYLWADALCIVQNGGEQTAQQLLLMAKIYASAKFTIVVTDGDASTGIPGIKGISRCASPTRWFCHSLRTENWGLKKGGTLTFGRPPYHTRAWTYQEHSISQRLLVFEKGQFYWICSSAAFRESSVSHCPALHQSHRFRSPNILSGYPDLQELRSMIFGYNGRDHSFPEDALAGVTGMLEVFSRSFEGGFLYGPPVMFFHAALMWRSSDKQKARRRLHSGKDHCILQGSHLPSWSWLGWKDSTVCFDENNGTLYDSFPATIGITQWHSHVSPDTSEKRLIGPCFPSTLRNDIRDYSLESQMARGWKADAYDPNVDGPFKPAYGNTVYRHSSLPNKKFWYWFPIKDLKNDSGPATTPQHAFISCKTRRGWFRTQGFYPGELQAVDANGYCGRIHVPKAEYDAYLPPGGSYKYLTIELVAICLRKNNPCGTPGYSDTDTTSASSSSSSTGTQPSTGYGSSNYEEESYGVLWVKWMDGVAYRKGVGEIYKKAWESHDLEDVDIILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8Y1</accession>
    <name>A0ABR1W8Y1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Proteasome subunit alpha type-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007690</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667347.1">
        <property type="nucleotide sequence ID" value="XM_066812005.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045065"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03753">
        <property type="entry name" value="proteasome_alpha_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033812">
        <property type="entry name" value="Proteasome_alpha_type_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 6 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="254" mass="28268" checksum="4B61EE50A79B3E97" modified="2025-10-08" version="1">MFMARSEYGKFFSDRLRVHVEGSTFSPEGRLFQVEYSLEAIKLGSTAIGVATSEGVVLGVEKRVTSTLLETSSVEKIVEIDRHIGCAMSGLQADARSMVEHARVESQSHAFNYNEPLRVESCTQAICDLALRFGESADGEESIMSPLWRRPAHCRLRRGRPQLYHAEPSGTFYRYDAKAIGSGSEGAQAELQNEYHKSLTIADAETLVLKTLKQVMEEKLDAKNVQLASVTKERGFRIYTDEEMAEVVGRLPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBG7</accession>
    <name>A0ABR1WBG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008666</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668323.1">
        <property type="nucleotide sequence ID" value="XM_066812981.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046041"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF147">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="57413" checksum="7949A121013664FD" modified="2025-10-08" version="1">MFSRDLMQSLFTDPLQWHFFVLVSAWLLYQLAQAAWNLSPFHPLSSIPGPRLAGATYLPEFYYDAVKFGTYTKRIQRLHEAYGPIVRISPNEVHCNDPAFSDEIYASAGRRRDKPLHQIRGSGAVSGAIFSTAGHELHRVRRNAFAKFFSRAQVAKLEGKVQRLVQTLCDKMMSAGGQPFDVTEAYSCLSTDVVSDYAFGESFGFLDQEAWKPNFRGPACSINRPVFLFRFFPASRYLSTLALGSMSRKGFKEPRPISMRVSGEKTRPCSAHFWSQISPEQEKSIHRLTDEAAALLTAGSETVSWALTVITYHLLDKPDILRRLCRELERALDPSGGLPSWSSLEKLPYLGAAISEGLRLSYGLSSRTARIATHEDLIYRGVWRGEPCQYIIPRGYAVGMSAALLHHDEDLFPDSHAFRPERWLLSGDGSIRNKELERHLLTFSKGSRSCVGINLAYCELHVGLAALCLRVLPNMRLYKTTEEDIKYDHDMFNPMPKRSSKGVRVAMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC30</accession>
    <name>A0ABR1WC30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">18S rRNA factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008877</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF2/ABP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668534.1">
        <property type="nucleotide sequence ID" value="XM_066813192.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046252"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12263">
        <property type="entry name" value="RRM_ABT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039119">
        <property type="entry name" value="ABT1/Esf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034353">
        <property type="entry name" value="ABT1/ESF2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311:SF7">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="127"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="260"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8081059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="325" mass="36508" checksum="50E80F014923B8EF" modified="2025-10-08" version="1">MAPQKRNAFLDADESEDDIGGYESEEELQKGGSRSAKRRKVDDSQSDDGDDDISSQDEDEQVAKGKGKSKAKQPRKAASGADEDEQDEGDSADEDDDDSMSGELPGLSKPLTKKNLVATEKAIKKSGVVYLSRIPPFMKPQKLRSLLEPYGKINRIFLSPRTPWRIRAECRSFTDGWVEFLNKKDAKAAVDLLNARTIGGKKGTYYRDDIWNLLYLKGFKWHNLTEQISAEAAERASRMRAEISRTNKENKEFVRNVEKAKIQDTKSTKAAAKTKKETADKKDPAPAPAPANESKVRRTFEQSSMAKKREDKLPEKTQRVMSMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCD7</accession>
    <name>A0ABR1WCD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668640.1">
        <property type="nucleotide sequence ID" value="XM_066813298.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046358"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8081165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="464" mass="53278" checksum="A6D1365467068F81" modified="2025-10-08" version="1">MYSKNHGCHLPIHPFKFPRLGILELLQNRRGGVFERLPTEIVFDILLRLDDLASLDCLLHASPVAYRIFDEFAVKVAETILHNGYGAALKGLHTKEPTTIGIAVAFVPMQIHLIAMIRSGTLPLNSLSDFVGRVIIPYQIGMDVVSLGLFQPEFRAMPTVPFVPPPLAEDTPPVIVRGLVSTARHLTSLSIDCLKFYRARFGSMKPCQPTVSAKQFESMPPEARKDLHMEPWNDQPRGRRVPVHDIGPPTWLEEQLVIRAFWCLQTIVDIRKAATSRLLHAEGWPREDLKHLRDWKRHNVYSLENPLRTLLGREIVCRTLASSIQYRQMMAVMHYLEAVHQRSWPDPHPTGQRLQVERDWPAPRRRRRDLERLGRPSKAHHLYNLLQSLSYTSLGSGAMRAGGLDEFRRYRFAYAWLSVLGADDRRALEGFRRKQGELVAKCKDRSERQAMEFNWLPYLMIDIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCI4</accession>
    <name>A0ABR1WCI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase family 31 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668182.1">
        <property type="nucleotide sequence ID" value="XM_066812840.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045900"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="684" mass="75120" checksum="430DDFA7E6B3D6AD" modified="2025-10-08" version="1">MFFSIGPRSRGRNRVRFHQIAGAALVLFVMLSILRMARRVRSARSPQRSIYDYTEGKVMPAAAAAAAGVAGATTTTAKKLSPEEEMAEYLRGLVSRHGLTQDITFHARRIQPVFKTRQKRESMTVIRKKFGPRYGFATIKVPAPAEEADHHELKRGSQQQQQQPLSPVVTGIDPAVLKLPLPGPPELPDQVDASPFLLGIATTYSRLVASKASLLHDWARWLTDGQGRSNGAELLLVLHRASTSEVGHVSAKLHELGIDATVRSSSSAAGVGAVGGSSPDSDSTWSYLELVGQLSRRAREISKEIENGGKKKTSEKKYLGLVDDDVFFPCMHRLVARLGKLDPKENAYVGLPSERADWTTTEEGNVTMTYGGGAVFVTRPMADAITKMPCARQPQLQPEQEAGIGGGTPPAPQAVEEAAATTGQWDERLYRCVAAHHSSRLRVMPSLYIPDDDAGDGGDGDYESGLQPLTLHHYRQRHQRFAPSRAHLIASLAGEGSFLHRFLFRGDGWVLVNGHSIAEYPDGVDIAPLSRVSSSSQKKSAAAVLVTQQPDKFIHAGIENRKDDNEEGRIADVRLASRITMDSDAAQKQERKDQKVVSWTGVKRVWQHLDSRIVKDEAGGIKEVWQAYVKRTEAALEYNDDRLDPSDTVHRQDGVSDPELRNCTDLGEGIMMSQLTKKLRGDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCN0</accession>
    <name>A0ABR1WCN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007727</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667384.1">
        <property type="nucleotide sequence ID" value="XM_066812042.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045102"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18032">
        <property type="entry name" value="DEXHc_RE_I_III_res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18799">
        <property type="entry name" value="SF2_C_EcoAI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050742">
        <property type="entry name" value="Helicase_Restrict-Modif_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47396:SF1">
        <property type="entry name" value="ATP-DEPENDENT HELICASE IRC3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47396">
        <property type="entry name" value="TYPE I RESTRICTION ENZYME ECOKI R PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="63"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="281"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="550" mass="60897" checksum="6555DCFFF78868E4" modified="2025-10-08" version="1">MRLSRLTWRAIVPLLHSPRKPSYIRALPARPYSTLQEKAEAPRHPQPVKLRAYQEECIQSVLSSIQNGHKRLGISLATGSGKTVVFTQLIDRVGPIGQRAKKTLILAHRRELVEQAARHCSNAYPDKTVDIEMGKIHASGLADITVASIQSIASGDRISKFDPSQFKLVLVDEAHHIVAPGYLRTLEHFGLDQKRDESPILVGVSATFSRFDGLRLGKAIDEIVYHKDYVDMIGDKWLSDVIFTTVASTADIRRVRSAANGDFQPGELSQAVNTEQVNEVTVRSWLAKAQGRKSTLVFCVDIAHLMGLTQAFRDHGIDARFVTGDTHKVERSERLSAFKRGEFPVLVNCGVFTEGTDIPNIDCVVLARPTRSRNLLVQMIGRGMRLHPGKTNCHIIDMVSSLETGIVTAPTLFGLDPSEIVEDATMHDLQKLKDLKTTDDQEPEETGSKAPPPSKGSINGQITFTEYDSVFDLISDTSGESHIRSISRYAWVQVDQGKYVLSAPGGTYIRLQAERNEEKEGTGAKFSAWEIRALPRAPRPNLPLQLPDSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCP9</accession>
    <name>A0ABR1WCP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009025</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668682.1">
        <property type="nucleotide sequence ID" value="XM_066813340.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046400"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057585">
        <property type="entry name" value="TPR_dom_fungi"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936:SF3">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936">
        <property type="entry name" value="PPR_LONG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24603">
        <property type="entry name" value="TPR_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="387"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat" evidence="3">
        <location>
            <begin position="505"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="874"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="909"/>
            <end position="939"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8081207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1178" mass="129330" checksum="68B9BDC6BA6CEABC" modified="2025-10-08" version="1">MPIYSSLYSNFIRQGLTKSLTHGYAQSVVAATHPHVLNSQNRSSFARPPDRLPQQRRLGLLVRPGPPHEPRHAERRVSHGNLDAYFEALQQKQEKQAEARAAGHDEEDLEKEWTQFQFPQPIEWKPSASSVLVESGPDAHAADAETEAILEAARNGADDAPAAIDAVSALAHINAALEKELESRNLLEALEESATSPVLASGAQSRALSPVLGQSRSASPLSIARSATPPVDPQSQTYADHLTKLTQDGRFAEIPAVFEAMLVANVKPIAAAYNALLVAAINIPNEKTQIVSKALDIYTDMMRRKVLPDGETYNILVGLLASRSLEVSSLKTAFESKLARFGGMDEPGKFMFVSSELDYAILSADDRLDLALSLFDSSVEFRKANYSSETYHQLITACAGSGRVPEMLRLFEHMELSGAVPFAATFPSMITAFSNVGDLASAVECYNEYKELAVAHDNGQYTLSDRLDSEVYAAVINAYVVSNRFEGAMQFYQKIIKEYDVRAVDIKDAIIRGGFVKAFTTRGIYDQALRWAQSVEDETRMATMADIATTAADAGDAHTAVAAFSHIAPNYKNIATPAMALMALCVRQTDVATATQYWQILSNPEVEATSAFIEPTAMYAVALIGSGHIAEGLTESEIMFQRIRATGIEARPQLAEEIEEGIEFISKFMAARNIEDPRVATPLSYVAPTFSTSTFQSTPTVSSFEDNFDPYAHNTDFKGSSIISDELEGAHGRKGPRLNEALTRFRNMRRAGRHPRYITYAKMISAAARESKMNLCHDILAMARTDVPLLTQYAVVRYGWSSILDAMVGACLTLGDRVLAEQYHLELLQMGAAPSANTFGLYITTLKESTKTFDEATEAVKIFHRAKAEGVEPSSFLYNALIGKLGKARRIDDCLFYFAEMRALGIKPTSVTYGTVVNALCRVSDEKFAEELFDEMEAMPNYKARPAPYNSMMQFFLTTKRDKSKVLAYYERMMARGISPTAHTYKLLVDTHATLEPVDMTAAEAVLDMVRASGQRPEPVHYASLIHARGCVLHDLEGAKKIFDSVMKDPAVPANPCLFQALFEAMVANHHVADTEAVVGEMRQRRVELTPYIANTLIHGWAAEKTIGKAKAVYDSVGREKREPSTYEAMTRAFLAVEEREQAKGVVSEMLSRGYPSAVVNKVLELLGGGNGEEAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE52</accession>
    <name>A0ABR1WE52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668210.1">
        <property type="nucleotide sequence ID" value="XM_066812868.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045928"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="258" mass="28146" checksum="D48BA17D7F25078C" modified="2025-10-08" version="1">MALFNPLQFFVFPFMIFVALPLAICAGITTVFAFAVLFLRLFWVYFDVGMETIRYVILGHTQPQQYIPSPSSSRLASASTSPQITRPPSPEATSPFRNSQRRRRKSRAGSVTAIAPLIGGLDGGSGASLGPAAGLGRDFEGVGGWRSDQNTEDERVWESLNSRLEMPDPLRYHFRSHSGSAVLIPGLAGAGTLARVSPRTGSTSPPDLRKSMSTSSPNSSRSRTPTRRMEGFTSLDRDGYFPLIPLQSKKLVSKTCRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WF01</accession>
    <name>A0ABR1WF01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668148.1">
        <property type="nucleotide sequence ID" value="XM_066812806.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045866"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="399" mass="42567" checksum="D72FAC93691285DB" modified="2025-10-08" version="1">MFSIIKRGRQQAKDHSAKVAEKTKDEETKKPYKHVPTHAALDAMAATAARQPSGLKASHDLTITATGVASREKSPNGSPDDAGRRNPDDPIRESTAKASSSSASVGSEDGLEMSPGKPGTTASPHVPPASSFSRPIPSRTNSSDSGNLHHLHPAHQRKTSGSDRYYPPSARSTQFTAPQPIDPRTIRNDPSIPPVPSLPALNFDQTFNHAAAAHSDSKSASSVSSFSSARNSGSVRNSASTAPSSILSKANQNSTSSFASLHPRPTDSVPATSQPQQAAQAEPVSPVETRQPRSEQVSKPGRRRLSKSRRPSETEIDTHQWNQVAPASAIPSIDAGVTAVKPMARTDSEHGGKKVFMPKITRRLSKTQQEMPSSEMPQAAPKKNRWAFLGMKRNPAATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFD1</accession>
    <name>A0ABR1WFD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-ornithine N(5)-monooxygenase [NAD(P)H]</fullName>
            <ecNumber evidence="5">1.14.13.196</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_009003</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-ornithine + NADH + O2 = N(5)-hydroxy-L-ornithine + NAD(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41512"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-ornithine + NADPH + O2 = N(5)-hydroxy-L-ornithine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41508"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.196" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668660.1">
        <property type="nucleotide sequence ID" value="XM_066813318.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046378"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025700">
        <property type="entry name" value="Lys/Orn_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF6">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15050)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13434">
        <property type="entry name" value="Lys_Orn_oxgnase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8081185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="605" mass="68167" checksum="D750BDAAF47F2D66" modified="2025-10-08" version="1">MTAKESTPEAQGSALSHDFAGTATKTTDNVNGHKAESPESQSQTHRFRDLELEQRYIDEPRKLRVVVVGAGLAGVIAGTLLPAKVPNIELTIFEKNADVGGTWFENKYPGVRCDIPAHVYQTSFEPNTQWSEEFAQGAEIREYWQKLAQKYGVYDRLKLSHNVAGLDWDATNSVWKIDVVDLQTGQQFTQTADFVLTAVGRFNAWKLPDYPGLHDFAGLLRHTSNWDPAFDPAGKRVAVIGNGASGIQVVSHLHRNPQLARLDHYARNPTWIADSFAGDATSLEPKPYPPELRRRFAEDPAAYTAWRKAFEDKYWRGFETWLRGSDRNHEARATLTERMRQRLLHRPELLESLIPAFSPHCRRLTPGPGYLEAITADNTDYVQTPIARFTKTGIETVDGKHREVDAIFCATGANVDMIQPFPIRGPDGREGGCGSRVPYTYLGAATPGFPNLFFVHGPNAAGRSGSVPHSVEVQVAFFARVLRKAAREGIRTLQPSRRAADDFVEYCDAFFRSTVLTEDCSSWYNGGRPGARIHGLWPGSGAHVETVLREPRWEDWEYTYLNRGGNRLMWYFGNGRTRKEEDPQSDMTRYVRDPSEIDLRTLHDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM21</accession>
    <name>A0ABR1WM21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alcohol dehydrogenase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005825</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669063.1">
        <property type="nucleotide sequence ID" value="XM_066810140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043200"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF5">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="7557" checksum="453DCA79161447B2" modified="2025-10-08" version="1">MASTDDSNMPKTHTACVYNKPGSCSVAIREVETPDPGPGEVLVRLTHSGVCHSDYGVMMNTASVPLTSNYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM77</accession>
    <name>A0ABR1WM77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Vacuolar protein sorting-associated protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_005910</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Endosome membrane</location>
            <topology evidence="2 12">Peripheral membrane protein</topology>
            <orientation evidence="2 12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the VPS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669148.1">
        <property type="nucleotide sequence ID" value="XM_066810225.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043285"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15735">
        <property type="entry name" value="FYVE_spVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21385">
        <property type="entry name" value="GAT_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16979">
        <property type="entry name" value="VHS_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017073">
        <property type="entry name" value="HGS/VPS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049425">
        <property type="entry name" value="Vps27_GAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21356">
        <property type="entry name" value="Vps27_GAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036956">
        <property type="entry name" value="Hrs_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0967">Endosome</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VHS" evidence="16">
        <location>
            <begin position="27"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="15">
        <location>
            <begin position="169"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="229"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="291"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="458"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="540"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="621"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="542"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="641"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="660"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8084639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="737" mass="81153" checksum="083B1A1E84AFBE73" modified="2025-10-08" version="1">MMGGWWSSSTNTALDEQIDKATSSSLEDIPLNLEISDVIRSKTVQPKEAMRSLKKRIGNKNPNTQLSALNLTDTCVKNGGSHFLVEIASREFMDNLVSLLHAVGPAAVNHDVRGKILELIQSWAAATENRYELKYIDEIYKSLQREGYQFPPRVTVASSMIDSSAPPEWIDSDVCMRCRTPFTFTNRKHHCRNCGNCFDQQCSTKTLPLPHLGIMQPVRVDDGCYAKLTDRPGKGAPNLSQERSPTSPSFPHKDRSASIMQPRNARVDDAFDEDLKKALAMSLEEVQNHSALGKGYVPNTTNTNQAKSHAPEPPTSKAAEEEDDDLKAAIAASLADMEEQKKRHAAALKEQANSSQPAAAGAPFVLPRNDYELSPVEAENINLFSTLVDRLQTQPPGTILREPQIQELYDSIGALRPKLARTYGETMSKHDTLLDLHAKLSTVVRYYDRMLEERLSKTYSQHSIGGYNLPTPRQSSGAYPPMHPNTPNHAGPAESFYTGEQADYTRGPPGHSYGQHPSQTTQPQQFFGYDKRASLSMPPVQYPQQTIQRSESWQSQGQAPAPSAPTQFSSSGYGPNEQAMQTSHTLSHAAPSQPGVNRGPDPGTTSIADPNAAFYYANNQQQDHDRQTPSLPGDSAPSPYPNLQQPAGYSIQSVPPTPASVPAQPSQPSQPQQQYQAPLPQHQQQQPPYWQQQPAGQGPQSYQPPNPAYPGYTQETFPSAPHHTPQQPAVEESLIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQH9</accession>
    <name>A0ABR1WQH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668843.1">
        <property type="nucleotide sequence ID" value="XM_066809920.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042980"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045993935" evidence="1">
        <location>
            <begin position="23"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="179" mass="19417" checksum="6C2DC785791A05D5" modified="2025-10-08" version="1">MVRVRIVALLAGLLGAMEMVSAAPTRSTSEVPSRVMVEEDLRPAAVVTPPPCVAMTPAPSVEETEARFDKFANAFLVTKNLTEAFEYIAASYRNHNPFASGDGPGPALDVLGPIWPSTQITVLGTTFNSPMSWLHYRNSMSGEIVDRYRWDAGCIVEHVSIRPVLEVVIRSDESNANAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQK8</accession>
    <name>A0ABR1WQK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670341.1">
        <property type="nucleotide sequence ID" value="XM_066811418.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044478"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="224" mass="25869" checksum="581AFE7D3D3BDABC" modified="2025-10-08" version="1">MKTRREVWEEWSRAGIQISKERRAKEEKKDPRIPYLAFLQAKANPKLYWAEFRRKYRKEPPLRDTNLADKDREKLYRDYIARLKLPLETQKKDLSTLLHSVPLKDLNNKTLPENLPSQLLADIRYVGIQASIRDPLIKTYIETLPPPPEEGRPWTTKRAGRRGPSGKQLKFSQAVLREEERGLERAQHIDGRKGITSQLLAEREKKGSDPVATEGSCEGTGESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQP3</accession>
    <name>A0ABR1WQP3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 94C1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006613</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669851.1">
        <property type="nucleotide sequence ID" value="XM_066810928.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043988"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="507" mass="56382" checksum="EE728C77EA92A4DF" modified="2025-10-08" version="1">MIYGTAQAQLSSKFDDVDDSVILVSMRQGPGLVLLGVIGILLSYRFLFRTPALLRDGVPLPKPPNTLPLVGNGILFLQARQKLFAWFVRCERQFGHETFQISVPSLPPGVVINDPRNLEYVFKHEGVFGKGDFFKQRSWDLFGRGIINVDGEPWRAQRRAGLGFLNAANLRVLTDVALPRYLGASITSQLMGKMAYNMEMHADDDFTKAFDYASGVTAERFQNPLWFVTELVTGARFRRSLATVKSFGEKIVRSAIEDRRSEKHAASESKLDEVSGTLIQSFLDTITNEGFVAEAALNYLSAGRDTVAQALTWTMMLLMHNRSATGKVRNEVQQLVQSLDGLDEAGDGVDPALSVNFTPVALPYTMAVFYESLRLYPPIPFEIKQCEKATTLPDGTFLPSKSVLVFCPWAMNRSRISWGEDADEFRPERWLVDGKLVTKSASEFPVFNGGARTCLGKKMAELMAAQVIATMILTFDFMPAYSTKRVSKSSLTLPMEGGLPCYVKTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWV4</accession>
    <name>A0ABR1WWV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_002615</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Secreted metalloproteinase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M43B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670548.1">
        <property type="nucleotide sequence ID" value="XM_066806930.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039990"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046225848" evidence="10">
        <location>
            <begin position="19"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="11">
        <location>
            <begin position="148"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8087654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="277" mass="29910" checksum="39ECA76B420E3206" modified="2025-10-08" version="1">MQFKPLFLGAVAASSALAADRLCGFKEPTAEDIAIAQSFAAQEAEALAASNETMSLQAQTNVNVYFHVIATSQSTSGGYISASTLSRQIDAMNERFAPYGFAFTQAGADWTVNSAWARDGSELTMKRQLRKGTYKDLNMYLLADMDYLGYAYLPKSVSSGSSDFYYDGVSILGSTVPGGSYTGYNLGLTAVHETGHWLGLYHTFQGGCSGQGDYVDDTPPEASAASGCPIGRDTCPGGGVDPIHNYMDYTQDSCYEEFTTGQVTRMNSYWKNYRASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX08</accession>
    <name>A0ABR1WX08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002647</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670580.1">
        <property type="nucleotide sequence ID" value="XM_066806962.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040022"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047864">
        <property type="entry name" value="Ribosomal_eS26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00733">
        <property type="entry name" value="RIBOSOMAL_S26E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8087686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="120" mass="13659" checksum="53135D5C61A7E645" modified="2025-10-08" version="1">MVKKRKNNGRNKKGRGHTKPIRCSNCSRCTPKDKAIKRFTIRNMVESAAIRDISDASVFAEYTVPKMYLKLQYCVSCAIHGKIVRVRSRVGRRNRAPPPRVRYNKDGKKVVPTTQTAKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX43</accession>
    <name>A0ABR1WX43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="8">ATase</shortName>
            <ecNumber evidence="3 8">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002623</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3 8"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670556.1">
        <property type="nucleotide sequence ID" value="XM_066806938.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039998"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11907">
        <property type="entry name" value="AMIDOPHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8087662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="559" mass="60772" checksum="4B049A72A854E3A3" modified="2025-10-08" version="1">MCGVLGLILGHVGDDPLAPCKAATDLHSALYYLQHRGQDACGIATCAAGGRVYSCKGNGLAADVFKSNGSRVADLPGSMGIAHLRYPTAGTSSSAEAQPLYVNSPYGICLSHNGNLPNAPELRQFLDREAHRHVNTDSDSELMLNIFANELNETGKARVNVEDIFNALSRMYERCQGGWACTAMIAGFGILGFRDSNGIRPLIIGERPSETLPGATDYMMASESIALRQLGFTKMRDIKPGEAVFIRKGGEPIFRQVQEAKSYTPDIFEYVYFARPDTTIDGINVFKSRQVMGYKLADKIRQLLGEEGIKEIDAVIPIPETANTSAASVAESLGKPYSQGFVKNRYIFRTFIMPGQGQRQKGVRRKLSPIESEFEGRCVLLVDDSIVRGTTSKEIVVMAREAGARKVIFASCAPPITYPHIYGIDLASPQELIATNRDRQAIAKVIDADSVIYQNLDDLKAACAECSPEHGPKEFEVGVFCGSYVTPVPEGYFEHLAELRGKKKKAPVNSATVASSGHTAAPHHIEQMIQDAEQARAGLASPIREDISLHNVASDADRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXI9</accession>
    <name>A0ABR1WXI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670774.1">
        <property type="nucleotide sequence ID" value="XM_066807156.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040216"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="87" mass="9611" checksum="325D975949631822" modified="2025-10-08" version="1">MSSSVLIGESCPVSIPVVVAVFVDQRGADCINMEELSSEVELWLSVHDRPDGFRTIAIDEQSMALECVEDEGLLRPKSQQKYSPRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXW7</accession>
    <name>A0ABR1WXW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase I associated factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670893.1">
        <property type="nucleotide sequence ID" value="XM_066807275.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040335"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009668">
        <property type="entry name" value="RNA_pol-assoc_fac_A49-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14440">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06870">
        <property type="entry name" value="RNA_pol_I_A49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="428" mass="47601" checksum="1A81AC4ADF2431D0" modified="2025-10-08" version="1">MGSKRKIDEGSGSSKEKKVKKARQAAPQQSQIVKIASVRSARECAPVVASTPGLSVPPLNFQAYTRPAKNQKKSKKASPPELLLHASTDRVDYTAKEDGDGGVESHLKHYIGVFDPATGKLDVIEAKKMTVRGVPRAQKPLEDNVADADFKTMTEQRNTLGMEFGTKKAKKAIASITENAIGPGRSNIEGATKLDSSSMAIMDSISEAARGIASREQLQAQADQAKPIQDVYKAEELIGADLISSIPIKDWQDIAKKQSPLTNPNKYVTESFWNVARSLHPVQNLRILRYLSCLLTISKNMRKGKDRGSFKLPDRKKLQELLDPAPVQLIDSIRRKFSDGGDVRKRHMDLLKTYCCALVSILENYEFNTEALRYDLTLTEKEFTQYYKQIGGKILVRKDPEGGKGKMQIAKLALPLEFPQMRFARRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYF9</accession>
    <name>A0ABR1WYF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671053.1">
        <property type="nucleotide sequence ID" value="XM_066807435.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040495"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="554" mass="59064" checksum="8608AA264181348B" modified="2025-10-08" version="1">MSKPLATPLAALTTVFTHSCSESWLLTTTRAPSRYPAFPTGGPASCEPPSWNDNIAFQGIRFYSPAICPSGFSVGPNCGVTKTRTQEGFPPVTSGETVAYCVPSDHTCTTDITDFIGGVWGFATATAPGAQVTVAPAIQIRWRDSDLSILQTHPLTPGLLLVGDRTLPTSTSPPPAASPTEDTSMRFSTVVPVPSQTSTLPAVSTTPLQSTTSPTPTGAPPQSTQSTVTLGQVTSTTSPALGASGGGGSPFSDTSNKPATQQGSKAAVVLGATFTALVLVVIAIFVVNRWWRKRQRRHHPESGNDHLTPIGVGVWARCGQKAGSWGVMLRRKSERRVYEKQREDTEAGLGGRGGGGPIVEVIVEVDAVPPLGSRANPAELDAHSEMELDVAHIRSSGGRRSTRSPSTPRPGTSSRPESRWTSSIFVGRTSADWEAFAKERWPNGLSVPPQAYRGERDNYSSSNNNYNRYTRSSGMTRSLSRNSRKLPSPPSSRLQQHIAVPEPKGHTRNKSSQFRLSERSDGTFGEMPHSPGFGFLPSPASPLSPRDHLSSRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYJ2</accession>
    <name>A0ABR1WYJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="5 16">2.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_003196</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:10868"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:64615"/>
            <dbReference type="EC" id="2.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Endoplasmic reticulum membrane</location>
            <topology evidence="1 16">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="5 16"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671129.1">
        <property type="nucleotide sequence ID" value="XM_066807511.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040571"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16 18" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8088235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="471" mass="52693" checksum="1E87415AE52AB912" modified="2025-10-08" version="1">MAATENGSKEESFTHASEAPETVQLSTKEGETTGEKQQPEESHASGTSHTSENTLADDQPTSTSYAEAVKEGPNGQGNGASKEVEEAPATHGINPNPQEQEVGSDDSYPDLDPLTIDERHTHEPDAPPPSSGGRIRWAPFNIPAERRLQTLTVLFHCTCIAVSTSVFFALCANPFIWPLLILYLLHMLTSRAATDGSLKYRSEWFRSSYMWHLFAGYFPAKLHKTHDLPPTRKYIFGYHPHGIISHGAFAAFATDALDFSGKFPGITNTLLTLDNNFRIPLYRDYVLAMGVRSVSKESIVNILTRGGSNKEGMGRAVTIVIGGARESLEAQPGQLRLILKERKGFVKIAIRTGADLVPVLAFGENELYHQLQPHEHPFVHRVQMFILKVWKFTLPFLHGRGIFNYDVGMMPYRHPLNIVVGAPVKVMQSNVVDDKEVDRLHELYVTELEKLWDRYKDEFSPDRKEDLQILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYR6</accession>
    <name>A0ABR1WYR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ZN622/Rei1/Reh1 zinc finger C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671179.1">
        <property type="nucleotide sequence ID" value="XM_066807561.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040621"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZN622/Rei1/Reh1 zinc finger C2H2-type" evidence="2">
        <location>
            <begin position="33"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="306" mass="33750" checksum="464BC8ACED877D83" modified="2025-10-08" version="1">MDTTTTGSSNGSSAALQLGDEDYIRPTFAPERCLFCNTQLDDLESNRLHMQMVHGLFIPSRDRLLVDLETLFDYLHLVIFGYNECISCGTKRSSPVAAQQHMLGKNHCRFDIDREGSEFADFYDFSDSGDGSQGDGDDEATDPVPHATKERVWTDDSSLRLPSGKVISSRSENVSGLLRPRKNPRAAEANRQHGGPGASTGIDLPQQPETSTSVVECSTSSGSKALTRSEKRENAFTTQLANMRAGDRQALAHLPLPQQRSVIAASLKQLKKARQLERRYQIATERSGNRTLMKHFVPDGPIRPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZP3</accession>
    <name>A0ABR1WZP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003566</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671499.1">
        <property type="nucleotide sequence ID" value="XM_066807881.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040941"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14134">
        <property type="entry name" value="PKc_CLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="379"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="210"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="758" mass="84239" checksum="49083A3CBD95E97D" modified="2025-10-08" version="1">MSTPTTATATIPPHHYRHHHTHHHAHYPPYPQLQSPVNPASYRTAGAIPSTLPANHLLPSPTGVPPPPSTISSSTASSRHGPASTASYSTYISGPLQPSHRRSANGATASVASTGAPAARLTHEYLGTDSESASTPRSDANIDTMSIPSSSQNVARKRRRSKGPDWTEFYKNGVPKEVIIIDDTPEPDGDGKDISSNYSTTTYTNGTAIGSDAGVSTRHVAKKRRKEDGYANGGRVVNGSHIATPNSATSSTDRTTSAQNTTAPTSLASLSSNGHYDYEASSATGQKRKRTRQQHAQEAKRRDIEALGDAYISYKPPQKPIKKSAEVAVRVVTDVRPTTITKRFKSSLLTPNKRYSNVKVDDEDGHYIVVPDADITQQYQIIKLLGQGTFGKVVQARDRKRNKLVAIKIIRSVQKYRDASRIELRVLQTLKANDEENRNRCIHLRDCFDFRGHICIVMDLLGSSVFDFLKSNNFVPFPNSQIQSFARQLLTSVAFLHDLNLIHTDLKPENILLCDNAYQTFTYNRRIPSSSAGTPRQANQRKVLLDTEIRLIDFGSATFEDEYHSSVVSTRHYRAPEIILGLGWSFPCDIWSIGCILVEFFTGDALFQTHDNLEHLAMMENVCDRRIDQNLAQQVTKMSNRSSSSSGNAAAKYFKRLRLDYPTADTTRASRRFVKNMKRLSDIIPTHSPFLRMFLDLLEKIFVYDPARRITARQALDHPWFKEAAIADDGTEAAKIRLERLRADPEYAHSRAPPSSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZP8</accession>
    <name>A0ABR1WZP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trafficking protein particle complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671537.1">
        <property type="nucleotide sequence ID" value="XM_066807919.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040979"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14825">
        <property type="entry name" value="TRAPPC2_sedlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="18763" checksum="32BC9EDCECC57D24" modified="2025-10-08" version="1">MSYYFAIVGTQDNPLFEHEFGTSKQGGDGMSRFNEAARHMNQFILHSSLDIVEEVQWGTSQMYLKHVDKFFNNFISCYITAGNIKFLLLHQPTTPNSAAAASSRSSTSIAANPTSPQTEEAVRNFFVEVYENWAKTIMNPFYRVNMEVRSPVFRQRVAAAGRKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0N5</accession>
    <name>A0ABR1X0N5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">mRNA export factor mex67</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003895</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NXF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671828.1">
        <property type="nucleotide sequence ID" value="XM_066808210.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041270"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14342">
        <property type="entry name" value="UBA_TAP-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057125">
        <property type="entry name" value="NXF1/2/3/5-like_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030217">
        <property type="entry name" value="NXF_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005637">
        <property type="entry name" value="TAP_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662:SF22">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24048">
        <property type="entry name" value="LRR_NXF1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22602">
        <property type="entry name" value="NXF_NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03943">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00804">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51281">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="9">
        <location>
            <begin position="385"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="TAP-C" evidence="10">
        <location>
            <begin position="590"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="634" mass="69304" checksum="12649E8D39D1B571" modified="2025-10-08" version="1">MAPTGPRNGAPRNNTRSAASGKSATRGGIAKRRAGGPIRVDRDGDLDMDAAAANAVGGRGKKSNPAPAGSTRKSTRTNASSSRPPRPTTKASHMVAKTLIVEGLQQSKARDNEGGGLKELLIFLERKATTAGKLSHSVRIKKSQLKGDLVYVTASKEDAEHIMKVNGFDWAGTKVHITEADDQAPNGAEASNLSAQTQDVKENLRTMLAQRYDPGQKLLNLASLGSDSLLIQMNMFQESTPQKLFRALMVICDEQFKTAQAKRDAISSVTLAGNNIDDVGQVMTLTETFPDLIHLDLSNNSIKELRGLRKWQHRLRKIETLLLINNPIDASNPSYKDELVSWFPKLQNLSGTQVRTAEQVAAAELANKPTPIPQSGPDFRDINGVGEQFITDFIRGYDMDRPTLAAKYYDDYSHFSLSVNGRSSHPPDIPLPQWGSYIKFSRNHVKITTTHARQQRLFSGTAVIQSVWQKLPATRHPDLATQFDKYIIDCHPISGLADLSGQSMAGVDGMIITFHGEFEDQDPETKVTTRRSFSRTIILGPGAPGRNPIRVASDVLTLKAYNPLPPVLGAAVANPAVPVAPQAPASAEEVQKQQMLAELCRQTGMNEEYSRMCLDVANWVFDQALATFHEKRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2N1</accession>
    <name>A0ABR1X2N1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004613</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672546.1">
        <property type="nucleotide sequence ID" value="XM_066808928.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041988"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13993">
        <property type="entry name" value="STKc_Pat1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="51"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="475" mass="52629" checksum="D1B13C71DD12FCA9" modified="2025-10-08" version="1">MQHVPAYGYPTPPASPSYAQQPFAMPPVCQSQRYTPIAPEERLGKFLGDSLQLIGILGTGAYGVVYSAIDIKTGIRYAVKTLSKFNMDGSPLDRRQVAFQHRELRLHYLASAHPNVVSMLKIVDDPDCTYVVLEYCPEGDLFFNITECGQYVGKDDLAKRVFLQILDAVDHCHTLGIYHRDLKPENILVSNGGETIKLADFGLATSSDRSEDYGCGSTFYMSPECLDPSSRRPFYYCAPNDVWSLGVVLVNLTCGRNPWKQASFEDSTYHAFTRSPDFLKTILPLSDELNDILGRIFTPQPGGPNYFTMQAPSAAQPCSLPASPEHINYACEPAAVDEDDFNNYPLSPASSDSDGESTCSSDAGSLISSCSTIDEFDDDEIPEDLSCPEPDMYDLEEPKVSFPQEFVPQFHNPAADVCQPCPCPVTLPNPVPNLCPPAQGKFSHFPYNFWDVIHRYSQPNPYHHPAPLLNLQGCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X306</accession>
    <name>A0ABR1X306_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
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            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045201098" evidence="2">
        <location>
            <begin position="28"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="327" mass="34345" checksum="4ADFC90D13C225CB" modified="2025-10-08" version="1">MLSISDAAALFLPLLVLLSIAPSLASAFSLNVAGPDWAFIADNQHLKASTSEPCRQAYSAPIACPDTLLGIVASMRPGFKPTTKDYEAMCTTTCKDALEKYVAGVRAACQLDAGDAAQLLTKATKPYEYEDLPVGIVGQIFQYHLAQSCRTDGRGSFCEFSTEHAEVDDDFECDDICSSTYFQNAHDYPGARYEFNYYSLVNESQWWEDQYLSGYDRLIACGKVRAPSAPTGSSLAPGSSATATATMSGGSPSTSNIDPLSAAQTTASSATGMDKASAETLSAVAASATAAVPFASAATTDLGSLNTLLVLASAAGAILLNKFMMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
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        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">PG997_004722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_066809037.1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RNA_pol_I_trans_ini_fac_RRN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790:SF0">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IA RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05327">
        <property type="entry name" value="RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="1"/>
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    </feature>
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        <location>
            <begin position="659"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
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    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
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            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="664"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="694" mass="79128" checksum="F6B094EA8BE3DA50" modified="2025-10-08" version="1">MQSAVAATTTATQLARSAAKPATPLKPILKTASSTLGKRRALEDDDLPSDGSSTDHLQSPRKRQRVEFDMNLEIHEVGARTVEEIKKEICKALDGHAHGDDEDYDILKEAVAGRQRIYDADDDDDDDELDKILPERRRQELKGYMVALTGFVPRLGRSASGLVKSVLRCQWLGRDDQFATVYTQFLGALVSAQGSYLNLVLEMLVDKFGNSRPADWAVPDFPTVTRERMQDRLHQAVRYLLRVFPAANVVLGQVIVSKFPYHDESSRVHLAYVDNLLRLRKYASQLQTDITDLITNRLVHIDVKMQMDMDDLDDRLTAMVLMALRSAQANGELPADDDDDESDAESVDSDDEEDEFNQIKSVKESIEKLDVTLDKLFKLYTPYFDDPDSPEALSTFETLLNEFSHIILPAYKSRHTQFLVFHFAQQSETLLDLFCGTLINTAFESNRPLVLRQAASAYLASFVARGAMVPGKHVRLVFEVLGHHLDKMRATYEVNCRGPDVRRYASFYSLTQALMYIFCFRWKDLIQEVPGDVDEDELSSYLDQDITWIPEVKEVLRRNIYSKLNPLKVCSPAIVEQFAPLAHRLRFMYVYPLIETNKRLRLSQFVSTSYANGGALRESGLDLNDESWQQLDSYFPFDPYQLPTSKHWVEGDYLPWRNIPGLNPDDEEDSDEEEIVEEEIDEDTATDDEDGRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X336</accession>
    <name>A0ABR1X336_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Involucrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_066809104.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042164"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="195"/>
            <end position="281"/>
        </location>
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            <begin position="338"/>
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            <begin position="661"/>
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            <begin position="711"/>
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        <location>
            <begin position="916"/>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="1048"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1392"/>
        </location>
    </feature>
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            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAK8089828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X387</accession>
    <name>A0ABR1X387_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004846</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672779.1">
        <property type="nucleotide sequence ID" value="XM_066809161.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042221"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029256">
        <property type="entry name" value="Heliccase-ass-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057931">
        <property type="entry name" value="RHH_ERCC6L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25806">
        <property type="entry name" value="RHH_ERCC6L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14773">
        <property type="entry name" value="VIGSSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="189"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="533"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="61"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="714"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="883"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="900"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="920" mass="103677" checksum="B5C886F7F90F9EE9" modified="2025-10-08" version="1">MASKSNTIEISDDFTTESEPESDSALANSSNPTELEKRKLQVEILDKVDWTDDEDDVTFEAFQRRKRQKSKASRKSTGKRPVTTAAARKDRGKGKSQRKGATSPDPEEDLPEKSLPQYLQSRRQNFDQDYEVLKEAGLRLTPDYSDLQFSEDERLEKLEEKPQFGPLSGVQPCRDYKDIQIKGTLGVIPASIAQYLRGILGDDMGLGKTVQVAAFLTAAYGKTGDKRDAKRMRKFRRATERWYPHLYHGTDKEDVLDSARAGRIEVMITTYTTYKNNRDQVNSVPWDVVVADECHSIKNVKAEVTRAMNEVNALCRIGLTGTAIQNRYEELWTLLNWTNPGVLGTMSEWKHTICKPLTIGQSHDATKQQLSTGRKTAKMLKENLLPRFFLRRMKSLIAHQLPKKSDKVVFCPLSEIQRQAYENLVTSPLVEFVKTAHEVCECGSGNKRGFCCHMVNANGDTWKALVFPIVMSLQKLSNHLTLLIPQHTEASAKQTRDLKYLQAAVPDNWHSLYNNRDSLLSLADPKYCGKWVVLKKLLEFWHGSGNKVLVFSHSVRLLRILQHLFGNTAYSVSYLDGSLSYEERQQTVDDFNSDPNQFVFLISTKAGGVGLNITSANKVVIMDPHWNPAYDLQAQDRAYRIGQVRDVDVYRLISAGTIEEITYARQIYKQQQANIGYNASNERRYFKGVQQDKEPEAKAGVNLVDIDMEKAVEDDDTQTIKQEKDADDGNGGLSQLAAMLTKDEKAKRPVSAIGAKPKRKSDAIQAILASAGVEYTHENSEVVGSSKIEDRLSRQAQLEGSQDTGPIGRAVFDNDDEGAGTTSTSFLYNPPEEVMQRQFCTMAKTFGFPNATEFALTVESMTQEERRNCLDTFYKKRLDYLERPDNAESEDDEATNGFLEDAKARMEQNRAARRAGQGLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3L1</accession>
    <name>A0ABR1X3L1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672899.1">
        <property type="nucleotide sequence ID" value="XM_066809281.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042341"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052778">
        <property type="entry name" value="Centrosome-WD_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220">
        <property type="entry name" value="WD REPEAT PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN WRAP73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="55763" checksum="0B79D8457BE5C852" modified="2025-10-08" version="1">MRYSPVLKSSPHCLPSPDGHYIATVSVTSILLREVASLDVVRAIRLPAEVVGSVTTFAWSTSSKRLLLASAEEIHVFDVAESSEYHATIRNPAISGAKSVFVDFGQNDNEVFVFSALGIKLSIFPLSSSQVIEVYNPKFYTPSLVVHGFSFRSQSGHLALLTRTSGKDMISIHSPGNRAVARSWSPDLIDAQGIAWAPDGRWLVVWESAAHGIRALFYTADGNLYRDWTGPRPASPDDTDYGLHAGVKQLTFSHNGHHVAVADYERSLYILSTSNLMQCFELVHPLGSIELRDTLQVWQETDATVSAFVKATQPVAPPGRASKTSQDLRTGCDHMSFDCSSATIATILADTPTTVWIWDVAALELRAVLIFHSNVSKVEWHPAQPELLFVKCEGDRSSGLVSVWDPLSGGPRAVDFQSHFAGGITNGRVSTFWVKSNLEVPTILLTDSNECMLGSLADEDQEVPWKEDPVEETRNDASDSATESDSQDSDMDPGDLDDTFHFKRGAGLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4C1</accession>
    <name>A0ABR1X4C1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GMP synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673146.1">
        <property type="nucleotide sequence ID" value="XM_066809528.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042588"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="40757" checksum="B839CA2552AA75FB" modified="2025-10-08" version="1">MSDWKGIVKKGWHPEKEGTTLRGQVTRQPSHHPPKRTVAPPPSVPYSTTTTASGKPPPPRPGSAYQTQQQQDEGVDEPVSPPKPYRVNTTGLSTSHLPPPPSRRGDGQTPPPVGRAPPPLPPSRGGSAAPPSLPPRLPPRSGTSSPVNRAQSPVHAQLPSASSGNLNQGARQQILLLRHHAAAPTCANRIPSSSSFSSKASSHMNDLSARFSRLGSGGGSSSSPTANNTATTPTAEAPAKTTGSVSQGTTWAEKQAALRTASNFHKNPSSVSFSEARTAAGTANNFRQRHGDQVASGMRTANSLGQKFGVVAPAAAGAGAGTQQQESAGINNKSQTQQLLSAAVAKKKPAPPPPPPKKKPAVLPPPPPQRQIQPSVDEDDAPPPVPLSTRPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4Y5</accession>
    <name>A0ABR1X4Y5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ABC transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_005409</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673342.1">
        <property type="nucleotide sequence ID" value="XM_066809724.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042784"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="485"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="521"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="853"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="900"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="986"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1091"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="321"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="596"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="864"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1186"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="570"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="806"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="573"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="816"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8090448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1428" mass="155251" checksum="D1CA442A767E4975" modified="2025-10-08" version="1">MASCGWEAEQQFGPAVAPCRRPPDFTLLFEEAILRLLPSCLFTVAAAIWSLPLLRQRARPGLSVLSCSKLGVATIFCLLELAILVWTSLNRERHTRATIPAAAVDLVAALGLALLIFLEHTRSQRSSLLIGLYLSLTLLLRAACARTLWFLYGGGFLASTSIAAIAVQLLLLATDSYTRLACGSSPKPSRSSPEESSSFLGRSLMSWILPLLLRGYRGSLDLSNIGAIDASLASSSLTSKFPRFISGHKDARVFLVSSFRAVGWYSLSPVIPRLCLSGFTFAQPFLTSAVIDYLNDFSARTSPGAAWLAPPPSSTRAWLCVSTAWYWNTSYKVSVMIRGGILDSISQKLLTLSMSEKGAEAKALTLMVSDVQRVVAALAYVHELWISPVETAIGTWLLWRQLGPSSLTVLAVALVSTTASIIVGKHIATQQGNWLAATEKRMAATKRMLSSMKAIKMLGSNRSVHATLEKLRLLEFAASKIFRRLIVGSLIASYSTVTLAPVVVFGAYIGTTLQNNAFDAAKMFSSLVLITLISAPLIRLLQIIPSFGSAFACAGRLAEFFRKEAKQDPRFLQQHTSGGSPSESSDFEKVEKDTLISVVDGSFGWERDASPMLTEINLNVRRGQHIVIKGAVGSGKSLLLQSLLGELANCSGEINVRGTVGYCSQNPWLENLSASDGIFSRVTDDLADDTQLRRVIVDACALESFLNTQTSGSTIGSGGAKLSGGERQRLSIARAIATRPSILLLDDVFSAIDQRTKEYMTARLFGPDGIARQWGITVLQTTHDDFIAQLADDAFIINPSGHLEPYGPPPRVATGSDVTTLPSQESQETPTKKTAESEQGPTKMMNDRQVYRAYFRSIGHLHMLLFFIGGIAFAFCLRFPDVWAMWWTEASTGAFSDSKSVGYWIGIYALLNVLPLIVVALWVMQLMLFIVPRSGVQLHEKLLRTVLNAKFAFLSAVDTGSLVNRFNQDLMFVDSKLPIDLLNTAATLFTCTAQVILIVVSAVYLLASIPVLALVLVLTQHFYLRTSKQLRVLDLESKAALQSKLSETLSGLPTIRAHGWQDSVHRDFQTKIDDSQRPVYLLYMVQTWLRFVMNMLVAGLSVLVIGAAVALRQSSVTSAAGIGVAVLNIASLGESLTNLLTAWTSLETSLACIARIEGFETSTPLEKEPLDPTAPPDQEWPSAGRITLNHVHAAYHVPSDEKETVWALEDICLDIKPGERVAICGQTGSGKSSLLLSLLSLIDTPLGTITIDGVDVANVSLERLRSGFLVISQDVLLRGLSVRETLDPDGNVQGDEQIVTVLEECGVWKPVEASGGLAATLDQVTLSAGEMQLLALARIVLEAGSRRGGIVLFDEAMSSIDVATEKRITELVGKTLQGRTVISILHRLEAALEYDRIVVLERGRVVHDGRPEEVREAAELFASYRTHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X502</accession>
    <name>A0ABR1X502_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005435</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673368.1">
        <property type="nucleotide sequence ID" value="XM_066809750.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042810"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF13">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="81"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="540"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="657"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="688"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8090474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="703" mass="76854" checksum="28022E7AE3483C39" modified="2025-10-08" version="1">MVAPTDSEKTAFGSESSTNGHATHTGPLKPANETVGERNERLDQEKKVLASNGTGERRELKEEEVEEQLGYAFPEWYKWWILTVIFLVQTSMNFNTSLYSNGLGGISEEFGVSEQGARAGAAVFLVFYAFGCELWAPWSEEFGRKPVLQASLFLVNIFCLPVALAPNFASVMVGRCLGGLSSAGGSVTLGMIADMFDGDHQQYAVAYIVFSSVGGSILGPIIGGFVEQYLHWRWTIWIQLIFGGFVQILHLLTVPETRTTIMLDKIAKKRRKTGEDPNCYGPDEIESFWDRFTLKELIYTWLRPFRMFLTEPIVLVLSLLSGFADALIFMQIQSFALVYKQWGFSPSQIGLSFIPIGIGYVLAWLSFIPAIKRNKSARARNPDDEHAQYESRLSWLLYLAPCLPIGLIIFAWTSTGPPLHWIGTMVGSAIIGIANYAIYMATIDYMICAYGPYSASATGGNGWARDFLAGVLTVPATPFYSNIGAEKGMNLPYASTILFCISFLLVAAVYVIYWKGPALRKRSPFAQSLASGTEEYQGRRLSLVRTHSRASDAGTGGASRRPSRAGPTTAAAAAAANGGQTSSTYDVADSSGMATPAHRSGTATPSGAKTPTRPGLGRDRFGPSSRRSSYYASKHAAERAHSRVASANHSRAPSGRNSHEGPRGEHDVDDVGEVGLHHEEHAQRLHNHLSTIPSTQPERNREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7M8</accession>
    <name>A0ABR1X7M8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673437.1">
        <property type="nucleotide sequence ID" value="XM_066806141.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039201"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="9698" checksum="1E04A50D48429B9F" modified="2025-10-08" version="1">MGIAAGITHFFASILEVIQGIFAAILHAFQFVLQCFVDLGKGAANFVEGTLGFAIHNFFILGTIAAAVFGYLLYVQRQGSTPVSRTMKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8G1</accession>
    <name>A0ABR1X8G1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lethal giant larvae (Lgl)-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002103</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat L(2)GL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673714.1">
        <property type="nucleotide sequence ID" value="XM_066806418.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039478"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15873">
        <property type="entry name" value="R-SNARE_STXBP5_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013905">
        <property type="entry name" value="Lgl_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10241">
        <property type="entry name" value="LETHAL 2 GIANT LARVAE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10241:SF25">
        <property type="entry name" value="TOMOSYN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08596">
        <property type="entry name" value="Lgl_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Lethal giant larvae (Lgl)-like C-terminal" evidence="5">
        <location>
            <begin position="480"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="860"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="863"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8091742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="951" mass="103877" checksum="383C914CD948DE8E" modified="2025-10-08" version="1">MAGFLRGKQSGMSNDLSPKVTPDLFAPDDRTRYGINSQISCIAYEPVQSLIAVGTRESKFGPGRIEVFGQNRVHKFLVPPRPCSFSDLQFCANRLVSLDTKNEIIIWDLDTGKRVVGFHCPGVVSCMVTDPMLDWCLLATQSGEVFAYDLDRERLSPLRIPNYWAERDPKARAIAIVSMQLHPRDIGKLLIAYTHGAVVYSFKQNKPTMFYEYQVPPGAPGGNCVATETTRQPRLVQALWHPTGTFVLTAHEDGSLVFWDGSNKDGRLVMARTLYDMDIHKPVPNKGSSSLAKHPYIRIAWCCKENPEDSGLVIAGGQTVDSPPDGLTFIELGITPNYATSTWSILSEYCKGKRQTIMTLLTSGEVSTMSFPSGYPISPTNQLHPSMSFVHPFAVKFEVATIERTRWLGMVETRNQGEALLKGGKEAPLQRRMFEGRSIIQVAHADGTVRIWDAGHGDEIENFTQLQVDVPRAVGRFEDVTVTAMSMASNTGEFAVGTNAGELVIYKWDGNRFYGRENDQQIEPNPGGLTDISSRTEPSLKQGLQPFRLYEMMQGPITATKVSDIGFIAVGSANGFFSIIDMRGPSVIYQATMSEFTKQDKRSSFLRGSSSASSVKEWPTAIEFAVLTLDGDKFSSICCFVGTNMGKLLTFVLLPEGNGYKATPFGVAQLNDKVVSICPIETNTGSPAVATGQSVAGLREGKQTQGTLVVVTSTEIRLLRPGTSKGASKSFDDYLCESAAVTKVNVYGVALVGIFGDRRSRAFSLPALSEINHAPLNMMDGSRSEDAIVDSDGNLFCWTGPAEIAILGAWGVGREIENTADVLINPNLIIPPRPTISNVQWLSGTQYVSPLDLDLLIGGPDRPPSKRMMEAAAAEKRGAPPASPRVATGEAEGWGDYLTRQLNERTEKLNLMGDSMEGAADASKSYADSASKFMKQQQRNMLLGGLKSKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8I7</accession>
    <name>A0ABR1X8I7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7580 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673725.1">
        <property type="nucleotide sequence ID" value="XM_066806429.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039489"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056002">
        <property type="entry name" value="DUF7580"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186:SF4">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24476">
        <property type="entry name" value="DUF7580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7580" evidence="2">
        <location>
            <begin position="208"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="496" mass="54892" checksum="D9F2DE2CC7E000B5" modified="2025-10-08" version="1">MLKVIAEGNSTLGKLVDLGVNEGMESGRQVRSAARFFSLTRRLSRNVFNAIRCSLSCRCPVAHTVNLELQPPYVQPTPYDDDQTVARQIFFRLTLMCDSSNRKAKQTAWLWDEVEIRAEIGQPKDSPELMARRPSPTPQGKPKKRVNFATFPSVSAMPTYTATQSSGSSALGSQVQTIDGIEVFRESLAVAMTGLSVGAASLGMPKPQGAIRDLQDLCHAIEESRRSEKLSGHACYGYVTDKTASTYNKFGVYPVQHSQGHHNNPSDELSIVSLRQVLESGGKSLPYLAFRHKQTLAATVASNVLQLAKSPWLPEVFDCEDILFVNLDGSPSYDHVFVSKRLPERDSPKTLDDGDDPKHHISGIVQNSTLFSLGIVLLELALGKRLRSLRKPTAIVTAATTTDEEESSPSQRSPTQDAERRDLLLDYQTALQHLNAVNIEMGPNYHDAVRRCIKCEFMHPTLDLEDDGFRQEVYGKVVALLEANLKNMNSSTRSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X900</accession>
    <name>A0ABR1X900_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enhancer of mRNA-decapping protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002259</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EDC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673870.1">
        <property type="nucleotide sequence ID" value="XM_066806574.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039634"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612:SF0">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DFDF" evidence="7">
        <location>
            <begin position="286"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="YjeF N-terminal" evidence="6">
        <location>
            <begin position="489"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="323"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="362"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="768" mass="83990" checksum="DFF996681E4759DD" modified="2025-10-08" version="1">MADQFLGMRMTVILNEPKDLTLVGTIYSIVPNQLLALHQVHILNTGQHLPTLDLNPALIKDIRETPQQSYNEQPPPNTAHADVAAAPAPPKPSNASFQDPAIINIGRRPTSIRNDENRNPQPPNTSEKRDPPSIVSPRPARSSGPSPAKRPDTAVLETTPLARALNKLTIDANASNAAAGKSPAVGDDLDQNDTTEDDEALNATPTAPRLLMGKQLLRRQRRGGRNGNRKNDGDATPTSSAKPTEQGPGWRQTPILQSTKSFQPFASLKKSQKGRQPPNADNGWASEDVTDVQEAGDFDFEGSLAKFDKRTIFDEMRQQDKVDDAERLVSHNRLPRPKPGTAGGKNLHYTENVLDVPSTTPKLKETPDDFWKSEADDATVNGGEKQMSGREGSGRNSRMRGDSRMSNSRRSQSRKASTSAVQGMGGPSRGNSNVRQPADNLAYQVHFRTHSGIRRSANTEKQPPLPISGEGFYAVPLNRRIETVTHLQMLNLENIAHNEIGLSEDLMAENAGRSVAEVALTALDDPAIKLRSATASPPNAPTIVVLAGNNKSGIRAISAARHLRNRGVNVLVCVVGIEREKELIEEFRRQIRLFRNFGGAVCSKAQLFENLSKNATSLAASSQVSVTLIIDALLGLSITFEELRPSDQATTYELMEWANRNEAFVLAIDIPSGVDPTKGTVNVIDGAKLYVHPRYVVALGAPKQGLLKAVEIGQDDGDLMVEEWKFYLADIGLGASIWRKAATRLRRGIDFDDKWVLEMKYRTLEDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X931</accession>
    <name>A0ABR1X931_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="4 12">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">5-proFAR isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 12">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_002337</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="4 12"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673948.1">
        <property type="nucleotide sequence ID" value="XM_066806652.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039712"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04723">
        <property type="entry name" value="HisA_HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011858">
        <property type="entry name" value="His6/HISN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02129">
        <property type="entry name" value="hisA_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090:SF2">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8 12 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8091976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="246" mass="27096" checksum="9D6D861C6B29A817" modified="2025-10-08" version="1">MTKFRPCIDLHAGQVKQIVGGTLDSSTDALKTNHVSLEPAGHFARLYRDHDLRAGTLSCWGPRTTRPPLRRWPPGQGACRSGAGSTTGTPGFTSYLFPEGKFSQERLDAVLHSLDGDKQKLVIDLSCRRRGEDRWFVAMNKWQTITDMEVNQETIKQLEPYCSEFLIHAADNEGLQKGIDETLVQRLAEWCSIPVTYAGGGRHLEDLDLVAKLSGGKVDLTIGSALDCFGGSGVKFDDCVAWNNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X955</accession>
    <name>A0ABR1X955_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002339</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the WD repeat coronin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673950.1">
        <property type="nucleotide sequence ID" value="XM_066806654.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039714"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015048">
        <property type="entry name" value="DUF1899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08953">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM01166">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DUF1899" evidence="7">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="127"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="169"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="377"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="435"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="462"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="576" mass="62641" checksum="9CDC90CA105C11F5" modified="2025-10-08" version="1">MSGRFVRASKYRHVFGKSTRKEFCYDNLRISRNAWDTNLIKANPEYLSVNWEASGGGAFAVIPLNEKGKVPEIIPYSAATLRPNPFNDRIVASASDDGKVMIWEVPQNFTLFTDAEEPADVSPVAKFGGHSRKVGQVLFNPAAENILASASGDLTIKLWDVNAGSASLSLKHPDIVQSLSWNASGSMLVTTSRDKKVRVWDARQERPASEHSGHEGAKNSRVVWLGEQNRFATTGFSKMSDRQLALWEPGTATPIGGFHTLDSISGVCMPFWDDSCHCLYLAGKGDGNIRYFEYENDKFEFLSEYKSGDPQRGIAFLPKRGVNVHENEVMRGFKTVNDSYIEPISFTPAMSTQEWLSGKEALPPKINFEDIYEGNPVSEVPADFKPTPAPAPAPAAKPAPKKEPEPAPAPAAARSPPPSMRDQGSSIAAMASKYEDDDAANDDDETSSFEEISKPVSRKPVSPTKTTSAPLPKPAALKSPTLTSPSTFSPTTASAPAPSSSSSNNNNTSTPAGVQNTLTEIKQLLETQTKMITSQGQQIVVLTGEVDSLKKRVGSGTQDQSERIRQLELELESLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9M8</accession>
    <name>A0ABR1X9M8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674199.1">
        <property type="nucleotide sequence ID" value="XM_066804426.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037486"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="1">
        <location>
            <begin position="34"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="116" mass="12974" checksum="4A258B2AC9C408F6" modified="2025-10-08" version="1">MDEAGVLEGIESNGLVFESAENRSIRKKQPGLKAWTSFIECVFAQGHALPPLVIFKGKTGWQFTVTENGWITDETAVEWLEKLFIPNTAPEDPSEYRLLVIDGHGSYKTTDFILSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9T9</accession>
    <name>A0ABR1X9T9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674243.1">
        <property type="nucleotide sequence ID" value="XM_066804470.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037530"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="200" mass="22688" checksum="153DFF8099882F8B" modified="2025-10-08" version="1">MYHQSATRSRVKREAMDRRVKQESIDNPSSGNMVKDESDDEKKPLDNYPAIKQDGQSTMKRARNHRPKSTYSFNWADSTSDAKAKSRILGIIEIPTDQAGRVIEAGKMTAIYHINYGQPIKTFVVYDGTEVLARVKDFEQETAVYELAALYFGAKLGWTHPDENDLDISSVPMEGEGTFAVKITLMRNEEPKKRKGPSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9W6</accession>
    <name>A0ABR1X9W6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT-NTPase and P-loop NTPases N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674208.1">
        <property type="nucleotide sequence ID" value="XM_066804435.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037495"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="645" mass="72780" checksum="DC78105A0DF95FBE" modified="2025-10-08" version="1">MAETLGAVASGVALAEVAGKAGLSVLKLKKLRDEVRNVPQTIADLMMQIECLDPAIWEAETHFADNDLSPLLWDHTAAQKSAQCCRIALQKLADLVGDLSMHIDSARGLKRKFSCLKVVLKKDELRTLEKRLETAVRMLQSAQNGYMITLLKLQPDIIVTKTVAQLTPSQQPLSATLLPESDAPEVAIHEDNTISNFSTERRNAMFRNRYSTSKRRVVRFQAPAWLLGVRKTWELCAQRSYGGWKINLRVYTVRPFLSPVFNAARVGDIGTLQRLFGTGEASPFDRDEGGYTLAHKYPQFMSILDRGGYLQETALTHSSDGCNCPLTGNWGFFQRLQPLCCPNHLRTSTKSKFKRLWNLHSPDVRVIKSIIGPSWGDEAHLLCNIFAESIYSYTSLIHIMAKLIADNVWDWKLQDTAMPSGLGSCSEFATEVIRNTRNIHVRLVIDIRGNATPSNYVPSGWCSPLVRLVLQLLVWGGPIRRTRVERLTRSGLLQWLRIVKDAGVDLSTYGREENEMMLNDWMARSICRWHTSESTQWDSRTYYPGWATVHYQLTWYLYGFRTGPEPEDEASMGRSLGSPRLLFRYRYLADTIHFSGKSYGMSQRMTFSGTFGLLSKIGLWIFRGLGSSRPIVSGYGTHSHLGLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9Y1</accession>
    <name>A0ABR1X9Y1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674223.1">
        <property type="nucleotide sequence ID" value="XM_066804450.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037510"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="102" mass="11317" checksum="ED441A9A1BCF98BB" modified="2025-10-08" version="1">MEGFLYQVFCRTAFWPRVLNEQFDLVGNGIVLMPQVYDRLIKPGSFLVMRMWALEPPTPSAPPPPPRGPGQRPTGALMPSPPPARGRTRRAGNSSRPVYVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA77</accession>
    <name>A0ABR1XA77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000265</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674353.1">
        <property type="nucleotide sequence ID" value="XM_066804580.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037640"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047010932" evidence="6">
        <location>
            <begin position="22"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="123"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="578" mass="61980" checksum="203FA3346D425581" modified="2025-10-08" version="1">MRPSTLLLATWQSAALVAAAATPYIPRSTDAAPGCYCMPGDACWPSADTWSTLNSTVSGRLVATVPIGSPCHDPTYDAEACAALQNGWSLPQTHIPSSSSVMHPFFANQSCDPFTPRSQPCLLGNYAAYAVNVTGKEDIQAAIAFAKANNIRLVIRNTGHDFLGRSTGAGSLAIWTQYLKNIEFSDWSDEFYQGPAVKFGAGVVGYEATEAVHAKGLVVVGGECPTVGIAGGYTQGGGHSALTTTFGLAADQTLEFEVVTASGDVVTASRHENEDLYFALSGGGPGTFGVVTAMTVRAHPDADVGGATLQMAAASTTQDKFYQAVSRFHELLPGMTDQGAMVVYYVASSVLMVNPVTVYNSTGDYVRDTVLAPFIATLNELEIPHKVSYSTHSYRDHYDTYMGPLPYGHVAVEEYNFGSRMIPRSVLENNNEGLQAVLKNLTQHGVLAVGDALNATAKYPGAAGANAVNPAWRTTGVHMQLTTAWDETAPWADMVEAQRRITDEFVPQMEAVTPGSGAYVNEADFHQPDWQQAFFGGNYDRLLQIKRKWDPEGRFYAIRTVGSDAWNVAADGRMCRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBR5</accession>
    <name>A0ABR1XBR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000789</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674877.1">
        <property type="nucleotide sequence ID" value="XM_066805104.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038164"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058841">
        <property type="entry name" value="HTH_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040554">
        <property type="entry name" value="KPWE_PEX14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36855">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36855:SF1">
        <property type="entry name" value="PEROXISOME MEMBRANE ANCHOR PROTEIN PEX14P N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25871">
        <property type="entry name" value="HTH_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17733">
        <property type="entry name" value="KPWE_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEX14-like helix-turn-helix" evidence="3">
        <location>
            <begin position="39"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Peroxisomal membrane protein PEX14-like KPWE" evidence="2">
        <location>
            <begin position="177"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="230" mass="25517" checksum="6B02518FCD35F35C" modified="2025-10-08" version="1">MDQSEVTASDSKANESQPPPSSAASSGGADMETGSNQSTIYRAFDSYPWTKDRIFQEQLSKELYTQHDASPSDIALACRIKRFEDKVSIKVDPAMYQVYRDEGAKPKVDLVPRFLLEQERLHEATGAMYQLTRSPLDNSRLPTDGGLTAPLWQLAAPKADLYIKRDDLASGDGGKEPYPKKFEEIIEFLQSGKEIPGIQKIPDTVITDPSITTTTGRPVPLKPWEKKPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBR7</accession>
    <name>A0ABR1XBR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000707</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674795.1">
        <property type="nucleotide sequence ID" value="XM_066805022.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038082"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR RGLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="60"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="375" mass="40749" checksum="BF1C00BE975CDD82" modified="2025-10-08" version="1">MMLNKASIAPNGFNQPLKRRAACDACRKRKIKCAGGTPVCQRCGRLVIPCHYSDVGRIGRPRRQRQAHDAASLTTESNSPLTSSPPEQSVPQNQTPVRATPLPADGLVQPTSSTVPEFDMAFLDNVPWLDWTNSASQMSPNIAWDNFPTPANETGEPQDAHSQSSPGRKGPCDWPGTFTIAAGGSTSSQKAADMRRLLRYGQGSQGVTGNVYLLGALLSNIASSYAQFFVQQKTRLADKENEQQTLILGHGPSASPDSLVELRVGSTEYLALLKSGIRVDATSLSAICDEFAQRQQKLHNEGHEQCVQGRPCQSKDASGCSKPSQHSHAICPKAETDDPRRFFLCFQAVRMVRASIEELQAVLEDEALASPYPRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBV3</accession>
    <name>A0ABR1XBV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000837</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674925.1">
        <property type="nucleotide sequence ID" value="XM_066805152.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038212"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF130">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTO (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="56"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="724"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="819" mass="91989" checksum="EF3A57AF47794B9F" modified="2025-10-08" version="1">MVDTTADTTAAAPEKITHPLHQEGRHDDDHNDEGSHSHDDSAAGHPPRKRQRVRLSCLECRRRKLSCSRELPCDRCVKSGTPERCTYEARPRGDGAVSDRASSALLSDHGLVSLHPGDSSHPRRDIEPSVLRDAARDHDRIKRLELEVSQLRNALSKQTSLDGTTVASPSTLRDGLKGSPAAAVEAPPGCANEPSDGLECQFVKGNQFKARYFGPHNSWSSFYQLHGLMPFMKETANQWLRPLNIQSKDRVKRKEDRDKRFLEPDASLEALLPPKTEVDLLVNKYLDHFEQLHRILHIPSFWREYNSFWDPTTPRYAAFTALVLAILSISNSLDEHAAKFVGVKSSSYQTAERWIKACDVWLDKQSQKHRKLIHYQIICLLHVARRINVIKKKRQWASSAALVANGISVGLHRDPDSVSTKITPFYSEMRRRLWATMMEFDIQSSFEQGLPTMLSQLDIQARAPRNIEDGAFDEDSESLPASRPADKYTFASYQHISRQSLQLRLELSQVLSGPTPHWDWDQATKYRDLVLQEIDSLPPLDQLTKDADAVSQPILGYTLLHLQLRQYLIPLHQPFLKLRQFNSKYQVAEYFYYNAARDLVLMHDRLFQQGMRALYFLRDDASNAAMNLAHVSLLQPKVNVSESLGLIVANSNDTIRLMEKCVAMKEDRILRVGNNDPWGYSSLCAGIGLLETHLGIKTPDAAKASSAERFISLHYKLLAYQTVDTSQPPSGPESYNGPKPNTPSSIYGASPLSSSLGMASTTVAATPTLSSASMPGWLMPMADPSQSSQVFGPNPDYNLDLLGTNLNDLWGIDFNENFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCI3</accession>
    <name>A0ABR1XCI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1742-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675081.1">
        <property type="nucleotide sequence ID" value="XM_066805308.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038368"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013640">
        <property type="entry name" value="Vfa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28218">
        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28218:SF1">
        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08432">
        <property type="entry name" value="Vfa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="21989" checksum="5F16B1440CFA1BB2" modified="2025-10-08" version="1">MSLPNVWHHRKVADSSAKGCDLCYKPTTSVLVTPDKQDHFYICTAHLKEVRFCKPIVDEAAIAAKKQKEKDDEIVAQAKKEYDEKQRKKKEAEKSDDKESKDKDKAKDSTSEAEKKDDSKPKDQDKADAEKASQDEEPRVFELQRTFYQQRLTKKRQAEERKRQAEMSQRNRERLSNPSFFPAVPKDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD76</accession>
    <name>A0ABR1XD76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="20">RNase3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PG997_001233</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675321.1">
        <property type="nucleotide sequence ID" value="XM_066805548.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038608"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1320.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-0930">Antiviral protein</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="11 14" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="351"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="19">
        <location>
            <begin position="541"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="17">
        <location>
            <begin position="907"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="17">
        <location>
            <begin position="1068"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="16">
        <location>
            <begin position="1275"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK8094548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1367" mass="154872" checksum="0E7C46D636FF023F" modified="2025-10-08" version="1">MVSDPDYFSDSSSEEYFDVGELEDMLPPQTEIEVGSQVTEEIDVPPSSQPEKTEANRATSLHARAYQLEMLQESLKRNIIVAVIWFLAPTITLCQQQYETIKSQIPSAQVRVLTGNDNVDAWSDPSIWNTFLQNVNVNAGARLMARYRDYKTSGRPVPFVLGLTASPAIGSNPGALEDLEKTLDAVCKTPLRHRAELLSMVNRPVLSILPFDVQLPSGRITPTPLMSNLHRVYHGLDIRQDPFVVRKRAENTERSRIELCNALDKNDTYVFRQMKSFCRRSEEICRELGHYAADYFIKTSLAQFVGSVQTNKVLYSSWEFNEKHYLSTIFGQVDTQLSSTENTNVSLKLQALIDLLLECDADTLGIIFVKETGTVSVLMHMISKHPVLGGQFRVGTMVGTSRYAGRRRDIGELNHEASLALDRFRSGELDLLIATNVLEEGIDVPACNLVICFDQPTDLKSFIQRRGRARMRESRLIILIEGGSARHLEWQQLEEDMKKKYEDDQRNLQDLDDLEHAEHEEAYVAPFCIPTTGAQLDFDQGKSHLEHFCAVLGSRQYVDTRPYYVLEEIDLPKGPQIRATVVLPPILPPGLRRIQSANAWVSESNAIKDAAFQAFVALYEAKLVNDYLMPLKDHELLRGVDSRASIIEVNNQWSPWPEIAGLWSNPQAYCHPLSIRGPDGEVLNEFDVILPVDIPDLQEFDIYWDTTPWKAKFGHPYPIERSGIDCGQTTALIKLAYGHRLKNKEFGQHVVQFDSKRGSVSIDDVGQHQFTQEMSLSFDGEFPYLVRISVNDVPYFYDRFLPSRPCDDLVKERNSYQLKDFTGEEPWLALRKWPRRRDFLHVMPANPVPGDAASVKPYGSAWPLSFCKVDATPISNVRFGSLIPSITHILEINLVARRLCETRLKSLHISDHSLVVTAISSPEAREATRYERYEFMGDSLLKLLTAVNVMAHHPYYPEGYLSKKKDLIVSNSRLYRSAIENELDKYILAKPFTGKKWQPQCVEDFASNTVVVDKRQMSTKTLADVVEALIWASYLDNGCRGPSLDGDLPKALDYPQANPCQPGAPPFLEPLEKLIGHTFANRSLLIAAVTHASYCVGASTETSMERLEFLGDAILDYIIVTELWKHDLPEQAMHLLRTGSVNADLLGFVAMEWTVDRKESRLDDDVPVEVTAQEPFWKFMRFDSREIALQQNAVEERYSEQRDAIRDALDRAPTYPWTLLARLGTPKFFSDMFESVMGAVWLDTGDMEVCRRLAERAGIMPYLQRLLRDKVDVLHPKNQLGEIAGDKRVRYKVRVDPDAAGPLPYSCKVYVGDRLLVDVAGGFKREEVQTKAAEMAYMLLKEHGLEYLEGCPVQNDCEDTDAIMKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD86</accession>
    <name>A0ABR1XD86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aspartic-type endopeptidase ctsD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001217</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675305.1">
        <property type="nucleotide sequence ID" value="XM_066805532.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038592"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF75">
        <property type="entry name" value="ENDOPEPTIDASE (CTSD), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045476831" evidence="3">
        <location>
            <begin position="20"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="138"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="475"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="538" mass="56440" checksum="BD1DFF7CC84E2529" modified="2025-10-08" version="1">MYWVATLLQLTLWISNTQAVNPVLVRHADGPHENIQQRDVEARDGLAGNNRAVGIPPLGFVTFKLTSTSQQRDEPHDNGVSRVAQNLARKYGSHLPGRTAASDHVLEGRENNYHIVKANPPGKSNSAGVDQDGTDYSYFVEAQFGSDGSLMYMLLDTGASSSWVMGSGCTSEACSMHNTFKSDGSSTLKDSGKPFSVEYGSGSVSGSLVTDTVKIAGMTVTMDFGLAKTTSQQFTSFPFDGILGLSIGNGGPQNFLVALKGAKVVDTNVFAVSLSRNSDSLNDGEIAFGAPNPDKYTGDIAYTPIDAKNKGSWAINFDDVSVSGKPVGIKDKLAYIDTGTTFAFAPPADAKIMYGAIPDASSADDGVTWTMPCDTKAELSFSFGGKSFKISPKDFLSAPDDKNRCTGNIYGMEVVRGAWLLGGTLLKSVYAVFDMDQARIGFAAKPATTPSTTSSAASTTVVKTTTLDGGAVVTTTMTSSRPGPTGVGLTGHQSSGPGPTKAPEETDSSTPGSAGEQLHIRGSYVSFFCIASILAIMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDB8</accession>
    <name>A0ABR1XDB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="12">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_001346</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="12"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675434.1">
        <property type="nucleotide sequence ID" value="XM_066805661.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038721"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17960">
        <property type="entry name" value="DEADc_DDX55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056330">
        <property type="entry name" value="CTT_SPB4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23681">
        <property type="entry name" value="CTT_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="11"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="250"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="489"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8094661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="592" mass="66385" checksum="BC5825D5822C899D" modified="2025-10-08" version="1">MRELLTLYAPVPLFLTNKDVVVEAVTGSGKTLAFLIPLIQRLLRIEDPTKRHHVAAIIVTPTRELASQIHKVLLDLIAFHTTSAELLPFLSDDFEKRPTTTTPFILPQLVVGGTTTPAQDLSFFLRHSPNILIATPGRLVELLSSPHVHCPQSSFECLVLDEGDRLLDLGFKPDIQKILARLPKQRRTGLFSASISEAVSEIIRVGLRNPVRVSVTVKSLKTGGIIEDRRTPASLQMTYLVTPASRKLPALVQILDKLEQRPQKTIIFLSTCAAVDYFQHVLPPLLPEGYQLVPLHGKHQPQVRQRNFDKFQTSSQPIILLTTDVAARVGSPSDVKVFIHRAGRAGRAGRRGLAVVFLHPGKEEDYVQFLDIRKTPITPLLHPEIDVSDAEASAVTEKIRDLVKEDRALHEKAQRAFPSFIRSYGKHQASSIFRIDDLDWTQLGRGWGLLKLPKMPELKSFKGDKKLGVAMDWDAYEYKDKAREKARRAALEAEDPAADAEKAEAFKSKRKRNAQAWSGKHEQEGVRTVRREKRRKKKDAESWNNMTEEEKLKARELDELLAEVRRQNQAKFAAEAAAGGDGQGDGEFKGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDJ2</accession>
    <name>A0ABR1XDJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">6-O-methylguanine-DNA methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_001322</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675410.1">
        <property type="nucleotide sequence ID" value="XM_066805637.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038697"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815:SF13">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="Methylated DNA-protein cysteine methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding" evidence="13">
        <location>
            <begin position="82"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8094637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="191" mass="20341" checksum="86C3CE8E710EF47A" modified="2025-10-08" version="1">MAISQKRKRNNNATADDGDSTEVALPIKKVPRASLDTTRDILAMRAAAITKKDPTSKTVAEGEEEEDMAPQLARIAASDRTPFEKRVLSALCQIPAGRVSTYGLLSAHLESSPRAVGGALRRNPFAPEVPCHRVVATGGALGGFKGHWATSTKDGVEGITIVEKKKLLRAEGVRIDEGKGRVVGSPWSGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE41</accession>
    <name>A0ABR1XE41_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001574</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675662.1">
        <property type="nucleotide sequence ID" value="XM_066805889.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038949"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.720">
        <property type="entry name" value="Haloacid dehalogenase-like hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051828">
        <property type="entry name" value="HAD-like_hydrolase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044924">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191:SF2">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="282" mass="30888" checksum="97F84E9FCB3552CD" modified="2025-10-08" version="1">MAKAKPNLLLCFDAFGTLFKPKHTVALQYAEVARQCGFTGFTDGELQSTLKTAIKDESKKNPNYGKATGLGATKWWTNLLHRFASKEGYDVEPGLVSTLRALKQPSSERRFDKIVVGVVTNSDDRVPSILSSFGLNVSPLRYGGKQQIDDAGVLARPDYDIDFHCMSYDVGVEKPDRRIFESAEHMLAQIVAARDDGKSMAEAGADVEGWQKVYVGDEHAKDVVGAMNAGWDPVLLDVDGDSDAASKLTESHGQTLADSFKERPVLTVSSIRELIMWLTGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE91</accession>
    <name>A0ABR1XE91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675780.1">
        <property type="nucleotide sequence ID" value="XM_066806007.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039067"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8095007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="282" mass="30473" checksum="F6087E14E4BE7A35" modified="2025-10-08" version="1">MKVLKPKSRPYPIGQLEVQRWGCGRGRGAREEVPGLGHPRPHRHAGSSTHFGPPVSAEGVRGVPRVPRRAVGHGADRLHLAHHLGVWGFDRLVARPVRIVRDGLRREAEVSVLDSDYLMIRVPGVKDAEGYAYPYFPSLSWRVWENHPFSVAAVGGYHPGKTRASALSNWDSDSSLPGPGENNGPNADEAATEQTDPPNEPGGIVFFVRRRGGQRLRVLVKSSYGTTASSSSSGPRFGLGLGQQRLRKSYPNLICVAGGVRITALLPLVKGSSASSGNTELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XED9</accession>
    <name>A0ABR1XED9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">R3H domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_001639</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675727.1">
        <property type="nucleotide sequence ID" value="XM_066805954.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039014"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02639">
        <property type="entry name" value="R3H_RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034069">
        <property type="entry name" value="R3H_Cip2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF17">
        <property type="entry name" value="RNA-BINDING PROTEIN PIN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="175"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="R3H" evidence="5">
        <location>
            <begin position="312"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="481"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="526"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="569"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="585" mass="64386" checksum="9ED508DAAB93546E" modified="2025-10-08" version="1">MNQQQHDMYYDYPPSANRSPGSTRQGYATVGLGSGLQGHRSAQRPMDNLGGPLGSSALYSPDERFDAMHRFDRLNPSSMQQQSGYMLENSQTWGYNNAGAATMNGPLNGNGRIGSRPVNRRAALPTNWTEQPAHGMHSMNQMYDGNMSMNDSDMDLADRVLTTPASGDSEQLIPTAIVIKNIQFQCRKEMLQGIMATMNLPQPYAFNYHFDKGVFRGLAFANFSTPEDTAIVIQKMNGMEVMGRKLRVEYKKMLPQEERDRIDREKREKRGQLEEQHRAPLPVHQQHALQALGVSVSKQPTGSPLRDVDLNDPDTLEYYTQLTLFKNDPSREVHIFPPDVAPEQRRQIHILAHNMGLEHRSVGEADRRQIQVMKRPQNSPPAHVQTQLPPNVSWEDHRRGLSRAATFDFAARRDGSGAYHTVGRQGPTLEVPGSPEYNNPQSLQKAKSFADLRKSPSPAPSGSSYAGIGNGFGASRYGDYNLTTPPNLTPTSAQNTSAGPDAMLANNMGGLNLGYDSAHLRSREAPGAIGSQRPGANGSAGRAAPDRQPRGPEWGEAFSGRNRGHMQRGSDSSDAGRSSGASRFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEQ4</accession>
    <name>A0ABR1XEQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675845.1">
        <property type="nucleotide sequence ID" value="XM_066806072.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039132"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8095072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="107" mass="11747" checksum="46E1CE10CA32CCBB" modified="2025-10-08" version="1">MDPPTCSECLDGFQLDCDDELNGAGLKVCQCKWKSGCRDGTVYGECIDLDCSGETRKSYHCDTDTVDPGMYPKGHCYCRDPSCRVEDCPDIDCGPGMQPACDPNMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UR86</accession>
    <name>A0ABR1UR86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_015413</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NRDE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660612.1">
        <property type="nucleotide sequence ID" value="XM_066819727.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052787"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013633">
        <property type="entry name" value="NRDE-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471:SF0">
        <property type="entry name" value="NUCLEAR EXOSOME REGULATOR NRDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471">
        <property type="entry name" value="TETRATRICOPEPTIDE-LIKE HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08424">
        <property type="entry name" value="NRDE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="136"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8061192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="494" mass="55473" checksum="EBC13DCD7356C77A" modified="2025-10-08" version="1">MTMKDRRRPGKAWISRGGRQRRLLLKHLQETTSWSTNAGDPLIRRYGGNNRYDVPAYRRYGRGRILGTDGFIRVEQLGSRDEFTIRGFYDGGGGGSALNNARKHPLAGSRRAGSEVVRVRAEKAATYTGVEDFLPLGGSVPKKRKRPESDASGASSDEEGPSYRSIHGKSKPHEFSDSDEEYGSDADGEWRARYLDDPIKARTVQLSQHTRQHPEDIDAWLALVDHQDTLLHIKDRDGQRPTLAEIRSFADIKLSMLEKALSHCTSPEQRETLLLRTMVEGAKIWDAKALAKRWEDVVREHSSSFAIWKAYVDFRQTSLSGLRYEDMKLLYISKMQQIKAALLAQGSGPVDQDLYAQLVIVFTRLTRFVAESGYCELAAASWQAIIELHFCRPASMTEGDNTNNDTMAVPQSFQGFWESEVARIGEDSAKGWAAFDMNGGTEEPRNQSPLTTALLCIPGTPTRPGRRRNSIGALIPESRPGLWMKVPRMTRTAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTS0</accession>
    <name>A0ABR1UTS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitination network signaling protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014424</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660926.1">
        <property type="nucleotide sequence ID" value="XM_066818738.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051798"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="582"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="884"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="631"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="775"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="899"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="955"/>
            <end position="987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="987" mass="106489" checksum="186983D25916DAAF" modified="2025-10-08" version="1">MPRAPSSAKRQQQQGSAASSSQNSNNSNRHDNGLVGPGKRLPKNLKSQGYLNATAANSKHSAASSSENVSDVGRGGCPASPPTIANTTTTPASLAASVATPPDADADDMANDSARRGSMSAFSESSSSESYNMAQGNGAVENHRRIDVNATKNTSVHRDTGPLEFILTVLRSCPAQDTIAILIILMQIPPIALSGIYVLFTLLTFVTTSSGLSLSEVFEWNLGAPSIATVVCVDGIVLLIWLFLWGPIQHVILDLAQMVIALGLGGGSRERDGGSMKNSLVCLSMILLSHILRHTKMKYSPIGYLLGSSRFMTPDIDDPLESLDSIRGYDKIQSGCVNWVRSVLAIHILTQGLVKYIRDWYLRRERRDNLAQSVDPEAGKPYAGDFSNDGGFSTPDSDAAALQPQATINTKKKRKQSAQIRNRQPLWAAIASTKIVVVKEYELTHSAADSADANATGIHNLGNAPFNSEADQIWISFVGCDEVSFNTSHFPAHSCAAGGAGGTSSHEIDLTKPFYVRVNNAIWQPTRIEPDKQSETSENRRRGVTWSGDIYGLTPMSNYECEFVSTTTHEILLSTSLRTTQAKTADVDQPNLKPSNQRSLRPDSPITTLRTSIAGAEVRYAEEKNRQRGIRKEWSRKMNALKKELEKLSSAVQSAGTGDDKMRQKIQQNQTQTKQAQHAIALLEAELKEFEGVPEALMSSWKAKQSAYNAERSSFDKALTEFKAFKALLDSQVKAMADEKSSLEGKRNKISSRIAKVDGELSRLADANARGLDEAERRRQDRANMENNFAKQEREYLERYNIVSSRAVEKEQVIGALKLEVEAVQNQHQAAIYTGALEYSDHMAAGQLPHGPAVNAAPYDPNMAWNQSAYNALLWGPSPLASGFVPQSSPLSRPRRMTQSRGRSSSMLSDVSGFTQSSSNDDVVDGSLPGSAQESLRPPPGFGFPAQLKGEGEIASIGSGSASASGSAPSSGSASVGDPSSPGPARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUS7</accession>
    <name>A0ABR1UUS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-tryptophan decarboxylase PsiD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014776</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661278.1">
        <property type="nucleotide sequence ID" value="XM_066819090.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052150"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022237">
        <property type="entry name" value="PsiD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF9">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G01730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12588">
        <property type="entry name" value="PSDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="L-tryptophan decarboxylase PsiD-like" evidence="3">
        <location>
            <begin position="49"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="442" mass="49725" checksum="03DF6D54D6B9C7D6" modified="2025-10-08" version="1">MSMRSLTTTGCTGKPGGWMPADHRVHRDWLAKQIKHVEGHGDKKPKLIPVLQEFKDMIEGNPRFYMYFSQMWEEVPHKHPYDKDPTGQAQIRDYEHMLDMLNHVFTKAPEWTDAAYGVGMVGVPMVGIFDYAMATPSGHAAFLDPDVNRMLKKILNEWGKFLQTPASAEVLNAESGWFGKHARTDLMQVANAPLKTSHTFEDMYICDPAKEHFGYKSWDDFFTRELREGVRPIASPEDDNVVANACESKVYNVARSAKIRDRFWIKGQPYSVGDMLAHDPLSAQFDGCTVYQAFLSALSYHRWHAPVSGTVKRCFVQDGTYFSEPLLENQDGQQYEIDSRGISMAQGYLTALATRAVIFIEADNPAIGLMAFIGIGMDEVSTCDITVKEGQHIKKGEQTGMFHFGGSSHCLLFRKGVKVDDFPDVDRSENVPVRSKVAVVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUT3</accession>
    <name>A0ABR1UUT3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lysocardiolipin acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661283.1">
        <property type="nucleotide sequence ID" value="XM_066819095.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052155"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032098">
        <property type="entry name" value="Acyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF16">
        <property type="entry name" value="LYSOCARDIOLIPIN ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16076">
        <property type="entry name" value="Acyltransf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="6">
        <location>
            <begin position="175"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="450" mass="51566" checksum="605CCA763958DEFC" modified="2025-10-08" version="1">MTTTSELRHRPNGKAVPGDEFDAFPMASPGVADAMLNMQQAGHPSGRPSTVGSGPNSAHSLRHYTSSEALWCKANPPSSTTGSYIANMLDEEEKEETRTDIYMVLAFLGAWFYFLNRDLYYAYMAVTKESFGLLVTTMTHWWAPTVIRISGDASTADQLSVTPDGRVECSFPDRMVMIANHQIYTDWLYLWWVGYTNKPRMHGHIYIILKESLKYIPIIGPGCMFFSFIFMSRKMAVDRPRLAHRLQKLRMKHEGPNGEEYLNPMWLLLFPEGTNLSDNGRVKSAAWADKIGVKDTAHLMLPRSTGTFFCLNELKGSVDYVYDCTVAYEGVPRGGFGEEYFTLSSTFFQGRGPKSVNLYWRRFALADMPLHDQTEFDAWLRERWYEKDALLEQYVTTGRFPANGAGIKGHIETEVRTQYWWEFIKIFTWLGCFGFFLTSLTRFLLKFRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUU8</accession>
    <name>A0ABR1UUU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014797</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661299.1">
        <property type="nucleotide sequence ID" value="XM_066819111.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052171"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF158">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="64"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="265" mass="29069" checksum="3A918373D1C30217" modified="2025-10-08" version="1">MLVIRVPATFCYIAAGPNAPWALEQLVTKKAPTYMNLSLIPALEPPPGSGIVPNFADPVSIAPICLVMIAITLPLMVIFLALRVYVRQWVARAVGADDVVFYLISVIVTLATCLPRAGDGGWSILSPSRGDRCFEEDSRFAEVQGIVGALIDLYVWIVPMTMIAKVRLSRKQKTGVYGVFATGFLACIVSIINAALRFEMFQSRDTLWIEVPVYALSGLFVQGRPTRPDTAHGGVPSLVSADYDYHAHLDRPWMNRDVAEDTSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1D5</accession>
    <name>A0ABR1V1D5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-fructofuranosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011751</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661758.1">
        <property type="nucleotide sequence ID" value="XM_066816066.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049126"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18622">
        <property type="entry name" value="GH32_Inu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018053">
        <property type="entry name" value="Glyco_hydro_32_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800:SF2">
        <property type="entry name" value="INVERTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00609">
        <property type="entry name" value="GLYCOSYL_HYDROL_F32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045672922" evidence="4">
        <location>
            <begin position="19"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="5">
        <location>
            <begin position="49"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="541" mass="59414" checksum="0CBEA2C5DA2661F7" modified="2025-10-08" version="1">MLFPSLLLSAAASAGAAAAQGVSTYVNPAVPTGTPIPANYTGPLRPQVHYSPPTGFMNDPNGMFYLNGVFHLYYQYNPTGLGAGNQHWGHATSKDGYTWENQPIALFPPEEKQYVFSGSVVVDTNNTSGFFPNQTNGVVAIFTLARYNEDGSGGPQTQAIAYSHDEGYTFQYYAQNPVVDSTSSQFRDPKVIRFEDHWAMVVAYSQEFALGIFTSTDLKKWTWASNFTNHGLLGAQYECPNLVKMPVRDRESGEVVDEKYVITLSYFIGDFNGTHFNTLDAATRLTDFAKDNYAAQFFYGVEGNQISLGWASNWQYAQQVPTGNNEGWRSAMTLPRASYLTKAPRIGWTMVDEIYDTKSIMGDSLATKTMGNGSVTVDYADVASNALYIEANVTGIDVAKATSFSTLNLTFTSPSSGESLRSGFYFGGDNPFFVDRGQLRGFDNVFFTDKFSVADVYYDSSADKTASWRVQAVIDRSMYEPLTMVNVAARDLPAGAKVSVAVWALKSTWAGQANKQGTVVGNVTTTSKRHMIYEGVSRHNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1W8</accession>
    <name>A0ABR1V1W8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trichodiene oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011904</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661911.1">
        <property type="nucleotide sequence ID" value="XM_066816219.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049279"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF147">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="58949" checksum="550C61261BCE9C80" modified="2025-10-08" version="1">MHSPSLLSFETLGASVLNSGVVLRLLGAWLVYRLLLALYNISPFHPLYKFPGPRLAAATFIYEFWYDFVRHGRYVNEIRNMHEIHGPIVRINPEELHCNDSSFVNEIYPGGGRIRDKHQHYLNANVGPVAVTAFGTQAHELHRLRRGALNRFFSKAQMGKLEPSVRRLVQQLCDKLLGWTDKPIDLTLAYNCLTGDTISQYAFGAPRGFLDHEGWDHNYKGALEGFTTYVYFWRFFPPLGGLVSLAPYFLWCIPETFALLMRELYVTIPGHVRDAAGTVFTDLLDADLPPDEKTVYRLAADGFSLTGAGTETTANMLTCATYFVLAHPDVRQRLERALECNGIDPTGKDLDWARLEQMPYLYGVVHETLRMCHGISTRLARIARTEDLVYRSQEGSLWGTAFEYVIPRGTPIGMSAGLTHRDPSVFPDPEAFRPERWVTEKGERNTGLEKYLLSFSKGSRICLGMNLAMCELYLTIAAVVLRVAPRMRLVSKSDDFVTMDHEVIIPKPKKGTKPITVVISPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V259</accession>
    <name>A0ABR1V259_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sec39 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012028</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662035.1">
        <property type="nucleotide sequence ID" value="XM_066816343.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049403"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013244">
        <property type="entry name" value="Sec39_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40787:SF3">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40787">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08314">
        <property type="entry name" value="Sec39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec39" evidence="6">
        <location>
            <begin position="2"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="751"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="790"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="790"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="808"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="858" mass="94849" checksum="43C9528012B0521A" modified="2025-10-08" version="1">MRHDKVLQTELVLRILLTCLPETVDSNKYVSLIECLRSEVAEDIEEDQCPEVDWSSVEHFTDAEAAKKVRKLRLLPLKSPNAPDDAAEDPISLFLIHRAHRVDEEAGLLTQLPDLIVPFLDHAPCIRAWMISALLPLLRRNYEYYPNAPIPQTLAAFEQLDDRAAISVLLDQTGARDGDLPQVGRDLRGLLGPWIYHEKRWKSQELAGQSSDAGSPSQRISCPGWEEMLEWLTLQASRSWRVAVKAIEEWEGPEDQRYARAALASAYLITEASVEALSGVNSIITKVMNLMGEDPCPTLQVASSLLSPLPDLTSELIASARNATYMRNDLLEESNVLTSPKKLSAQLLHALTLSAFILTKSGALCNVRRAGELAFLQDEREQKAEASKFLRNLRNHAPKTEDKYWMRARNELLWLRDWGAEEASDSVSDLRIQGVFGQLNREFLEMECLKAILTSGRYALARSIYEDSPEPPLPTELLAETIIGSAMTAYDNASNPNRTRGGLLKADDIIHAFPKTIPEDGPAARKIEALLKATHGLGEYRLVLKQGEPFTPVVLRVHSDPISIIGKLLEQNPKSYTRLLALLEIGENMVKAGLPNQEKSSKFHTSSESAATDQQFVVEKRITAMCVDAALTEDDFETAYSYVVNRLASTGGPVQMKAANGDSCSTTFDEYSWKAALQAGKYRRTAPHGVSVDRLANRAPATLQEILNVFRRCEEELDAAIKAEEQQENAWDNQGDNTVQAMPGGFNSTVPAGVVKYSSPKSSRQQEEAPMSLFDLSRASITRAQRNFSALSSLQQSSGQTTTAVKEGGSEHHSEADEAARVRKRDQLREAAVGTLASGVGWLIGATPAVNNQAQERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2D6</accession>
    <name>A0ABR1V2D6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012102</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662108.1">
        <property type="nucleotide sequence ID" value="XM_066816416.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049476"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046579595" evidence="4">
        <location>
            <begin position="25"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="114"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="6">
        <location>
            <begin position="424"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="330"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="384"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="519" mass="55262" checksum="3074CBCBA0AF2ECE" modified="2025-10-08" version="1">MVHTARAKSMKLSIAASLVATAAAQNGTYDSSTIRWAPCPADVAAPPTLCGELLVPLDYTNNESNETLTLQLAKVPATTQPSRGSVLMNFGGPGNDGRTMLGQYAPFLPLGSGGEFDLIAVDPRGTGNTIPFSCYQNETLRRAGQATVRQDWANSSDATPGRLWAEAQVLANDCGNALANTTGSLVGTAFTARDFMEVVDALGEDGMLRYWGFSYGSYLGSTLAAMFPDRIDRMVLDGIVNIHEWQSGIEVESVTDYDKTFKGFLDGCLTYPDNCALAHASNGENVTAAALESSIYDLLDRIKLAPFALGSSIIDYSALQNLINAGLRQPPPGPSWPRSSTPSSAAPTWPGSGPSSRTRPWSTASAAATRPCAPRTPRPWPLQRRPRRPQPPGRRPRRRHYDAVRALAHGGPRALRGRLPGIRTRHPILLIGNYADPVTPLASAKNASASFEGSVVLEHKGFGHASIAQWSTCTITAARKYLLTGVLPAPGTSCEVDQPAFAPLPGNGTAAAARRRALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2G5</accession>
    <name>A0ABR1V2G5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Folliculin/SMCR8 longin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662138.1">
        <property type="nucleotide sequence ID" value="XM_066816446.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049506"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021713">
        <property type="entry name" value="Folliculin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037520">
        <property type="entry name" value="Folliculin/SMCR8_longin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441:SF2">
        <property type="entry name" value="FOLLICULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441">
        <property type="entry name" value="FOLLICULIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11704">
        <property type="entry name" value="Folliculin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Folliculin/SMCR8 longin" evidence="2">
        <location>
            <begin position="271"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Folliculin/SMCR8 longin" evidence="2">
        <location>
            <begin position="376"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="527" mass="56359" checksum="A5FCB29427D654E5" modified="2025-10-08" version="1">MVVTHRPPTSNPLLTSHIQLCLAHYCDLHGPTPLMVTEGLPVPCSHCYDDRLDQGRPQTSAAAASQPNNVTDAMRKMHLTASRSTSLPASEQEAQRAAVRRTSSKLSTSKQAIPATSAIETPPQSPRKAPEAPSSHDAHSRTDPNFRRTYDPDVTKSASPCQNCALTLPKRQESNGSREQDKKGNPQAEMRGPTLRTRTPYARVYGGSSRDTSPPNSNPQSSCASDEEDVECSPTDVTSRPPTALRRPVTSASQSSVSSKSSLQSHTHYLDYTSTHEPQIANTYSIVRASCLRTLSFETLPRRPEHASNYSASMSNPAVNAMPSAPLSPFAPSPSAALSHHNAPASQSSGGPIFLVTRLLATRQPSSSAYLTATHEAFNFLASKFQELADWIVRLAEIEAEREREREEGNSPITSLQSQYTNGSQYGSGNGRGGDAPGPRDSGIGLGGGSFDREKPADRDSGSSFLTGGSRSGFIQRMGSMGGSMGPGGFAPKARGLAELVGLPDFFIELHAKFVTLLLELSVVMGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2U0</accession>
    <name>A0ABR1V2U0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662236.1">
        <property type="nucleotide sequence ID" value="XM_066816544.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049604"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="471" mass="52624" checksum="F73EE359F1EA002E" modified="2025-10-08" version="1">MLDENLPTFFSRLSSENPLSTVVYFTQNGAEPTPEYTFRRPNPQRPESKNKFALALGDVSSQDVIFAEVLIEPEWQQPTLSAAEIRAQNGVLPPPVPLIPDGFVIQLYNPDQQVAVKGEKSTWTGKESWDFELPQQSFRMPSASQLDRQQNDPVASELTPKVCFKWKRDSKFSKDMTCYLTGTSLAGKKNKDPDITIALYKQGREPGLTVYEPNLRRVEVEDRKGLEVVLLLAAETIREIYLFPSRDSFNIPGVPPPARRKNSRPIPASSSPKPLSSSSPAHTMSGGLGNGVPAASSSSVANNMTPPSRRQTAEIDAETKRLQAMVEQEEREREKRDQAEQKRIKKMLEEEDKERRRRDAEIAQETERLRREYGIQGQDIDAQRPAVPPRNSQQLHPNGMAGGMAQPPPPPRPMSAEPPRNSYMHGGLSNWWHAHGGRGGGPPQQQAGPSRRRGISDAAPNKVQKKHSVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3H8</accession>
    <name>A0ABR1V3H8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Pre-mRNA-processing factor 19</fullName>
            <ecNumber evidence="16">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_012490</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the WD repeat PRP19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="16"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662496.1">
        <property type="nucleotide sequence ID" value="XM_066816804.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049864"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16656">
        <property type="entry name" value="RING-Ubox_PRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038959">
        <property type="entry name" value="Prp19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013915">
        <property type="entry name" value="Prp19_cc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055340">
        <property type="entry name" value="RING-Ubox_PRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08606">
        <property type="entry name" value="Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 16" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12 16" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="14 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7 16" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4 15" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="U-box" evidence="17">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="276"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8065743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="477" mass="51504" checksum="1A1DD69B73D3FFA1" modified="2025-10-08" version="1">MLCAISGEPAEEPVISKISGNVFEKRLIEKWIEENGKDPVTGADLTLDDLLPVKTARVVRPRPPTLTSIPALLSTFQNEWDAMALESFNLREQLQRTREELSTALYQNDAAVRVIARLTRERDEARIALSKVSVSNNRNATANDAADSMAIDSDTLPSEVVQVIEDTQAMLSKSRKKRPIPEGTATSADISSYAVQGPVPGPVEDMSAFAHRDGHVAIGGHSGQVVFYNSVQSKLEYTLTLQEPVTASAWINYKIVLATASGSVKVFVDQQEVASFSEHSGPVTGLAVHPSLQLLASVSSDKSFVFYDLKESKRVARVFTDSALTTCAFHPDGHLFAAGTASKVFMTATGEQATSFSLGAPVHAIVFSENGFWFAAAGEGENIVTIFDIRKQGDAAKVKTFETGCAVQSLAWDYSQQFLAIGGSTGVVVQHYAKSSKSWSEILRSDFPAKGLDWSPNATQLVVADQKGQVAILSTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4A1</accession>
    <name>A0ABR1V4A1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Class II aldolase/adducin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662766.1">
        <property type="nucleotide sequence ID" value="XM_066817074.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050134"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="16"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="263" mass="28417" checksum="0B85B00C784A0B72" modified="2025-10-08" version="1">MDQEALEAAALSVVHRKLIGGSHILHHHHVLDAYGHLSVRHPTKPDVFILSRDAAPATITSPRDLVEYWVKDAAPVDPDHAPKGFAERHIHSELVVHSHADAVLPYTINGVPLRPCYHMAGFLGHWSPVWDIASARAGAGGSSSGDMLVRTEALGAALAQQFKYSTTVVLMRGHGFTAVAGAGGIEEVVFRAVYTAQNAAVQTTALTTQAAYHSRNDAPLQPIKFLSPEEAEASKNMASDTVMRPWGLWLREVEASNLYLNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4I7</accession>
    <name>A0ABR1V4I7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012854</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662860.1">
        <property type="nucleotide sequence ID" value="XM_066817168.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050228"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="412" mass="46110" checksum="6E923344947BD6CE" modified="2025-10-08" version="1" fragment="single">VKFLWLLPAADLEDIVFLPTDPAYDASLTYYWSATIRANIASIGTGAKWGAVMLEIEKYNRTATGGREGDVGVGGLLLGGGLSFHTRYRTWYRVKRCRQLRGRARQRFRHRRQCKNPPGLIQSTKGGSNNFGIVTRFDMLTFEATPGGIYGGLSSMSYDQKETMLRAFVRMIDINEANPADTGVLILEYNSPGPAAIMMAVVNLDGMENSTSFEPLQNVPVTSRDVKRRTYGEYITAFQQPGGSRKVWFSLCFKNDVDIVNKAASLWEEATSEAESALPGGGWGLNSVFQPLAKFYGQIGGSQNVLGLDETLEHDSIIWLADATMSTPEQEAYLQSAMRNLTDTLEAYTVEKGGYTQWRYLNYVDPSQNPLESYGKDKVRLMKEVADQYDPDRFFQKRVSSGFKISKIDNDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4N0</accession>
    <name>A0ABR1V4N0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012896</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662902.1">
        <property type="nucleotide sequence ID" value="XM_066817210.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050270"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="600" mass="67284" checksum="F8BED15ACED48AF1" modified="2025-10-08" version="1">MEEYDCVVIGAGWYGLAAAKQYHCTEPEASLLIYDSQETLGGTWADERLYPGLKTNNLLGTFEYPDFPMDTATFGVEPGQHIPALVVNKYLRAYAEEFGIANHIHLQTKVRSAEHYDETGGWTLSVEGPDGGNTSVKARKLIIATGLTSDPFLPHFEGQESYGGKIFHGKYFKQNSETLHTAKNVTVFGGTKFGWDAVYAYATAGVSVDWVIRSSGHGPCWVAPPYVTPLKKWIEKLANTRFLTWFSPCIWGWADGYNPIRRLLHGTFVGRIIVDAFWKILGNDALTLMKFDSHPETAKLKPWTEAMFTGASFSILNYETDFLDLVRSGKVRVHISDITKLGPGKVHLSDATVLDSDVLLANTGWKHVPALKFLPEEIEKDLGLPHTPTENGLEEDLANQQLLVKKADEEIFAQFPRLRKQPVWNRFYVPLTDQKGIDSDDAVTPCTPLTPYMLHHFVVPPSARFLRNRDVAFAGIVSNFSNAITAHLQGLWISAYFAGSLAQDPAAACAGNTGELEELRYKTVLYNQFGRWRYPTDWGSKNPNFIFDAVPYLDLLLRDLGLPVHRKNGFLAEWTDPYGPEDYRGVNEEWQTKYGKVEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4N4</accession>
    <name>A0ABR1V4N4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662905.1">
        <property type="nucleotide sequence ID" value="XM_066817213.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050273"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="242" mass="27601" checksum="B7593759FA0B02AC" modified="2025-10-08" version="1">MRDRATLLLAHARTQTLNQKRLEAYLAASQEPNLDIAQRLEEPQSSNPSSKHRRSKSKSKATSGADTPRDLNARVKILELYTLHVLLRNDEWDYAREFISVSSVLDEERRDAFLQALHSLQEDQQEQQRNEREEQERQDEQLREDLEEAKRLRSENETREQKRLEEERARREGSEVDYGVEKTPAAVNGASNGRRTKEGSSALSKPKATKGKPVGAPSLSARDDDFLELESRPRAVGIAAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4R0</accession>
    <name>A0ABR1V4R0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662932.1">
        <property type="nucleotide sequence ID" value="XM_066817240.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050300"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="99"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="37062" checksum="4B5420A38DFA290B" modified="2025-10-08" version="1">MTEKTQPPYPLHESVLGRIDAEYESFYNKHIFDKQQVHLQPIEASRASGILIPGAGPLHPVGSTVDHSFPRKESEGPDVKVRCFTPEGEKPEAGWPVCIYFHGGGWVLGTIDTENVIASNLCARAKCVVVAVDYRLAPENPFPAAVHDCWEAVLWALGDGKTTLGLDTTRMGTGGSSCGANLAAIMCQRAADRGGPKFSIMLLSVPVMDNTADETNNESWKLNQFSPALPAKKMLWYRYHYLPNKEDWKHPEASPLFWKGDWSKLPPACFVLGELDVLRSEGEQFGKKMEDAGVKADINIMKGQPHPFIAMDAVLEAGSRSITLFCDALRNALHGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5C6</accession>
    <name>A0ABR1V5C6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histone H1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_013146</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663152.1">
        <property type="nucleotide sequence ID" value="XM_066817460.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050520"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="5">
        <location>
            <begin position="18"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="22319" checksum="53AE2B771201504F" modified="2025-10-08" version="1">MAPKKAEGTTAAPKTKSAHASYQDMITEGIITLKERNGSSRQGLKKYVKANNNIVATEKMFDSLFNKALKAGVEKGVFEQPKGPSGPVKLSKKSKPAAAKKEGEKAAAPKKAAAPKKAAAPKKAAAPKKAAAAPKEKKEKETTEKKAAAPKKAAAPKKTAAKKEAAPAAEKAATKTKTGRVSKPKAAAPAKKAAAPKKAAAPKKAAAKKEAPKAEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5Q5</accession>
    <name>A0ABR1V5Q5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013286</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663292.1">
        <property type="nucleotide sequence ID" value="XM_066817600.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050660"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF48">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="54512" checksum="40AC433E15CD9C85" modified="2025-10-08" version="1">MDTSAESTRRYCWECQRRRLECDSTRPVCNKCRQAGVVCPGYEDKKPLRWLAPGRVTSRSRKCKAPAAKEKKKKKDEDSAVSLQAKIDAAMERAVRVPAEMYEGSLVPVVHLRDDVSEAPLAHFGPSPYTSPIPLEVMRFFTGPIRRTYICLALGHYLHQTRPPKAERVELWYRFHTEKGLSLRGISEEVVLEKRIQGLDQTVLSIMCLMLVDLSYGSPRNWRVHFLAAMKALACRGGIKQLHARNPTMQPTLKYFMILGVVASSTSPPEDYLVTTPELDFLEEVYGKGDYPTVLCPPFLFLIISQINRLRLQTTQPPEMHDPDSPSPQDLLSKILCFNPDAWASLYPESYQQLFLLARIYHSAVALYCISALRNLFPIGFLYNLLMLRAAHADCLFGLLREAILSPQTKLCLMWPLNVAGVEAATRSLSDRLFVEEALDELSRGLGTGYPLVARSAIQKLWDSGKTEWDDCYDRPYAFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6A9</accession>
    <name>A0ABR1V6A9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Orc1-like AAA ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013204</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663210.1">
        <property type="nucleotide sequence ID" value="XM_066817518.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050578"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056808">
        <property type="entry name" value="HTH_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36168">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36168:SF1">
        <property type="entry name" value="ORC1-LIKE AAA ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24913">
        <property type="entry name" value="WHD_AAA_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="3">
        <location>
            <begin position="162"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="AAA protein C-terminal winged helix" evidence="4">
        <location>
            <begin position="396"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="557" mass="63665" checksum="7CB1BE17CEC744A6" modified="2025-10-08" version="1">MFLGRCGSRIGRTNVSGQAQRAADLMQRQRLQPITAQRASFASTSRRAQQQYQQQQQQHRQQGARHEQSSTQDPEPSLRSKMVESAVTTLGSVLVLAGGFALAAYAYHKSYKHLQLRKMTNAFQPGDPVLELAAHRNDAPDPDAEHWIPRPEQAKIDKIIHGEGKGHYFLIMGEKGSGKSSMILEAMRKTDGDGVSMFEAHADLEIFRIRLGKALDYEYHEDYIGGYFSERGPRDTTALLDIERAFNKLEKVALRYRKNKNKPLVLVVNQCHLIRDDDDGKDLLELLQQRAEQWAASNLVTMIFNTDDYWVYERFKQLAARMEVIPVSDLPKTQAVAALRKYRAKYFKENVPLSILEQVYDRVGGRLNFLNRVAKSSNMMATCDRIKEIEKTWFLNQCWILGMEMDDDVMDQQKWASAAMVLAQALVNKEQDMENTYDNVTGHVLPSFQMHKAQQIMTRSDFIRELDRLNLFTITSNAEVRASSVPMHLAFKEICSEEGFGQFLEDTLQRISDIESLGRTRELVAKDLVLGGKYEFKQGWRGNVSVQLKEDPSKDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7E4</accession>
    <name>A0ABR1V7E4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxidase</fullName>
            <ecNumber evidence="8">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012993</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="8">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peroxidase family. Ligninase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662999.1">
        <property type="nucleotide sequence ID" value="XM_066817307.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050367"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001621">
        <property type="entry name" value="Ligninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00462">
        <property type="entry name" value="LIGNINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044997347" description="Peroxidase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="175"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="374" mass="39735" checksum="7F5A0811D3375A53" modified="2025-10-08" version="1">MLWSNVIATSVALAGVPSALGYPGMGEQMAEIMSRQSANDGFDSTELLGDLQTLPDNQLTPTASTTAWSAPRLGTAACQKDTCCVWQYIVNDMVAEFKGSSGRCTSWARRAVRLGFHDAGTWSKTTAAQGLPGGADGSICTTDEINRADNNGLQDICQKVNGWYNTWNKQKGYPVSLADIIQMGATVATVVCPRGPRIKSYVGRVDVAQAGPPNLLPGVDNSADDLIALFRDKTIGPHSLTALVGAHTTSQQFFVNTSRAGDPQDSTPTAPEWQKFAGAGGQKDWNEDFAAGYIRLSLLGVNNINKLTECTKVLPGGIPSFTPNDQANVDKWLNTADQSPTAKKISDALHAGQSLLGWLFSLINGILGGLKKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7G8</accession>
    <name>A0ABR1V7G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Inosine triphosphate pyrophosphatase</fullName>
            <shortName evidence="8">ITPase</shortName>
            <shortName evidence="8">Inosine triphosphatase</shortName>
            <ecNumber evidence="8">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="8">NTPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">XTP/dITP diphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013888</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ITP + H2O = IMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>XTP + H2O = XMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663894.1">
        <property type="nucleotide sequence ID" value="XM_066818202.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051262"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03148">
        <property type="entry name" value="HAM1_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027502">
        <property type="entry name" value="ITPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="RdgB/HAM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067:SF9">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="69"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="151"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="177"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8067141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="198" mass="21776" checksum="A729991F68410860" modified="2025-10-08" version="1">MAASSPEVNFITGNANKLREVKAILEPAGIVVRSQAVDLPELQGEIEDVTLEKCRVAARQVGGPVLVEDTCLCFNALGGLPGVYMLTEDNSKWFMKHIGHEGLNNLLAAYEDKSAEAVCTFAFSKGPDHEPILFQGRTPGKIVPARGPGHFGWDPIFEYEGETYAEMDPSAKNKISHRFRALDKVRTWVEEGMKEDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7T1</accession>
    <name>A0ABR1V7T1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014001</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664007.1">
        <property type="nucleotide sequence ID" value="XM_066818315.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051375"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8067254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="34214" checksum="6B29F29DB96A9077" modified="2025-10-08" version="1">MASTSQFLASLARLSISSAPRPAASSIPRFLAPSVTTQIRCASGGTAQMQARQREKEKLKRKRRQQRFKEYKYAVPTGKGEQFSLCDAMRYLRAAEVGRPPSSVTYEVALKVRTIKNGPVIRNRIRFPYPVKNDTRIGVICAEGSNAMHDARTGGAVAFGEQSMFDLIKANANNLPFNRLICHTDSVSALNKAGLGRVLGPKGLMPSLKTNTITKSVKTMMHEMVGAETYREKIGVIRIPIGNIQFSPKQLSENVKTFIDSIKADIARMEDRVDKDIIEVVLTSTNGPGFTLNGGFLPTDEKVDPAHLATAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9A1</accession>
    <name>A0ABR1V9A1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663598.1">
        <property type="nucleotide sequence ID" value="XM_066817906.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050966"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF9">
        <property type="entry name" value="L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="46"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="275" mass="29588" checksum="671B30FC98A85D5B" modified="2025-10-08" version="1">MPPSTFRSSLTITHVGTATAILEVGGVTFITDPYLSPAETSFPVGPGVVLTSHYQPSHTLESLPPIDAVLLSHEDHADNLDPIGRRLLDGRRVLTTVDGARKLAPRPGVVGLNPWEMVPLVIGGRRFEVTATPCQHLPGGECNGFIVTASEFGSTFGDDGVSRPNAIYFSGDTVYLEELAQMRERFHISLALLNIGAAAVMPPGGEGGEPLLITMNGRQAARLFREIGADVLVPMHFESWDHFTEGRDQLAAAFESEGVLDKVVWLELGVPRSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9W8</accession>
    <name>A0ABR1V9W8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663506.1">
        <property type="nucleotide sequence ID" value="XM_066817814.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050874"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021838">
        <property type="entry name" value="DUF3431"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37490:SF3">
        <property type="entry name" value="DUF3431 DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37490">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11913">
        <property type="entry name" value="DUF3431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="343" mass="39325" checksum="1711DA7DA8A831DE" modified="2025-10-08" version="1">MYSSGPRSYRRLALSAALLSLFLISWLYLPATRLTRQQLSTALAHAHKNPWAAPTTTPQQDQEHTNARVELVVSSVKAENTSWITDNFPHYPAHIYVADDPYAPLTVKHNIGHESTVYLTYIIDNYYKLPDVVIFIHGRRYQWHNEDPMYDGVPVLQKFRIPYVLSHGFSTLRCSWLLGCPLEMKPNLDAAARWDDPAADQRLKTEAAYAKAYTQLFPGQPIPESVGVHCGAQFAATRERIRGRSLEDYKAYRQWLWSTELTDEFSGRVMEYSWHQILGQPAVDCPNAGTCFCAKFGLCDLKCEEHGCKGRYFFNFGELPPEWPEKGTGQNGWPSKFWYLYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VBQ9</accession>
    <name>A0ABR1VBQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664121.1">
        <property type="nucleotide sequence ID" value="XM_066818429.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051489"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="92" mass="9583" checksum="7D0A008BD6713EE1" modified="2025-10-08" version="1">MRYKYTNHLPSNASSGGTGGAKPSLSTTQRVKLNTRPLGQAILGGAFKDAFSVDSLDKASFRSVGETNVTDPVVAPPDAEGRCAGTGRDPRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH46</accession>
    <name>A0ABR1VH46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664275.1">
        <property type="nucleotide sequence ID" value="XM_066814985.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048045"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="43131" checksum="DCD09A79B314E4BF" modified="2025-10-08" version="1">MPENRAAYLMGEKVRPLAVKPAPYTSPRPKPAPRPRRGRRRQPHRVHQAGPGRPPVRLGQVPARPGLRRRRHRRRSRLRIFWRGGAAAGSTSTSSSSKRFRPGDRVVGQALGSEKKFNDPAMGAFQHYVLLQANMVSPIPDALSFERAAVLPLALSTASCGLFQKDQLALRHPVVATDEEGGEEQKKKAGKETLLIWGGSTSVGCNAIQLARAAGYEIVTTCSPRNFGLVKSLGAAAAFDYRDPAAAVAEIVQFCQGKTVVGALSMGSDAGRGCVEVLRQLPKNGSRRFLSRVSYATPEDKDAGLPARIWCMLSFSVWLWVQSVRHGIESNVVVGTTLEGNEVGKAIYEDFLPRALATGRFVAAPEPEVVGKGLEFVQTTLDKLRRGVSAKKLVVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIH8</accession>
    <name>A0ABR1VIH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Btb poz-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664495.1">
        <property type="nucleotide sequence ID" value="XM_066815205.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048265"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="47"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="38110" checksum="A531153B6623C290" modified="2025-10-08" version="1">MAMPLSHSSSSDNNGEDELIETTEPASIDETEKMLSPEKLLKCGDLSDVKVSCGEQSWDLHKAILCSRCPFFERALVGQFQEARTSHVILRENDPDEVDGVIEYIYTGKAYSLPVSSVMSNHLLKDENTAAYVKMFELGDFFDLPSLRQHALQLLDDEFLAGLVEDVCRHREWGNPCKCRRRDVFKCHPDKLASLRHVVEFAYGGGVAELQLDTYEPVRRLLRQFVARTFMQVVRLPTFRKLLRKVPALGADLFLSMAEGDKELGAHLLVDPPYSCRSCGQCLHSFKDTRAEADNLLEPTINMIFWGTWKMPTVFGAIGSVITFRSLQAWRSVGRGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJJ1</accession>
    <name>A0ABR1VJJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_010588</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664193.1">
        <property type="nucleotide sequence ID" value="XM_066814903.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047963"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14136">
        <property type="entry name" value="STKc_SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="75"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="231"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="454"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="251"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8070385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="555" mass="62533" checksum="36F2FFE03AEE5C3F" modified="2025-10-08" version="1">MAVLGLQYSDPKSQTSSGDQKVHKLSQSHEPTFPTSSSGPEDAAENTADEEDSEDYCKGGYHPVQIGEKFKDGKYTVVRKLGWGHFSTVWLSRDNNSGNHVALKVVRSASHYTETAIDEIKLLQKIVQANPNHPGRKYVVSLLDSFEHKGPNGVHVCMVFEVLGENLLGLIKKWQHRGIPRDLVVQITKQVLMGLDYLHRECGIIHTDLKPENVLIEIGDVEQVVKKVVKSENSADKENHRNGRRRRRTLITGSQPLPSPLNASFNRDNMFPSQKSQTSLNAMMQDSAAATSDNKSPSEKSGQREKTASSPDKKKRKRKGPIINVKIADLGNACWVSHHFTNDIQTRQYRSPEVILGGKWGASTDVWSMACMVFELITGDYLFDPQSGTKYGKDDDHIAQIIELLGPFPKDLWKQGRWSQEIFNKRGELRNIHRLRHWALPDVLREKYHYKDSKDLTPKEREERERKLAKEAAENDDAPDEETTPALEYQPSQVADFLLPMLELLPEKRANAGGMANHPWLNDTPGMEEVKLNSLVPGSRGEGIEGWATEVKKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJN0</accession>
    <name>A0ABR1VJN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ADP-ribosylation factor 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011626</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665231.1">
        <property type="nucleotide sequence ID" value="XM_066815941.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049001"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04149">
        <property type="entry name" value="Arf6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041838">
        <property type="entry name" value="Arf6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8071423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="186" mass="20809" checksum="BF0E16D5251BC913" modified="2025-10-08" version="1">MGGQLSKMMGKIFGSKEMRLLMLGLDAAGKTTILYKLKLGQDVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYFSGTQGLIFVIDSADRARIDEAKQELHRIINDREMKDSLLLVFANKQDVKEAMKPQEVTEALQLNKLKDKVWYVVPSCATTGEGLLEGLAWLSNNVKAPPAPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTH7</accession>
    <name>A0ABR1VTH7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009224</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665501.1">
        <property type="nucleotide sequence ID" value="XM_066813539.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046599"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43391:SF14">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY PROTEIN 7-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43391">
        <property type="entry name" value="RETINOL DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="31432" checksum="DD797A281D6715E3" modified="2025-10-08" version="1">MPAPPEQVATNVAAVSAFCQQRHSETYPYIDPLQADLSAQTVVITGASRGIGRATAFSFVRAGCRRLVITAQAKDVRGATLDVLALALDVTDTASVEAAAKQVADHFGGVVDVLVNNAGFLSATEPLAAGAAADWLQCAEVNLKGLYRVSRFFLPLVLQSATSKTVINVGSQAANYVVPGMSAYQTTKFALCRLTEFMAMEYSDDHGLVAVAVHPGCLRTELASNMPEMYHDLLVDAPELPGDTFVWIAKEKREWLSGRYVEANWDMEELEGKWEDIVKRDVLKFRMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUE0</accession>
    <name>A0ABR1VUE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665377.1">
        <property type="nucleotide sequence ID" value="XM_066813415.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046475"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045602005" evidence="2">
        <location>
            <begin position="23"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="23260" checksum="6AC98A1F672057EC" modified="2025-10-08" version="1">MHGQTLVQLIASGLVASTAVSGFQLNNGNHGLSRRAAGALSLFAIPAAAAPVAEIGADVEKRSPNPDPKKKKAKNANGAAAGNNGAAANGAAAAGGNGGKAKAGGAAAGGAAAGGAGAGAAAGGAAAAPAAKASGAAKAGGAGKAGGAAAGGAGAGAAAGGANNAGKAKASKSAAAPRAAAASKTAGAGLAKASKAPKLPKASKAAKAPKASKAAGAKAAKASKAPKASKAPKAPKASKAAGAKASKAAKAPKATQSAAPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV07</accession>
    <name>A0ABR1VV07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665952.1">
        <property type="nucleotide sequence ID" value="XM_066813990.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047050"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045013618" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="21"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="429" mass="46827" checksum="98E1CE43DBC436C0" modified="2025-10-08" version="1">MRANFVLVALSLAVSCTLGVQNVVRTNCGVYNGRNSAKDGTTRWLGMRYAAPPVGDLRFEAPQDPQCVDGIQEAFRHGKYCLATGASPRDIQTSEDCLFLDVYAPTNASTSSRLPVFFFIQGGGFNSNGNPNLDGRRLIQASNHSIVVVTFNYRVGPYGFITDGDEITPNNGLLDQRKALQWVQTNIAKFGGDPRHVVLGGASAGAASISLQLAAYGGQDYGLFQGAAAESISFATVLTVEQSQYQYDNFTHRLGCAHGQNSNFTSSLACLRSKTAAQLQAKNHNIPYPGASGPPLYMWNPVVDGDLLRDVTYNSYAQGNFVKVPMLIGDDTNGGTVFTPRNTSTLRQSDEFLHNQFPYLRPDQLSTINKLYPNANASCPAAGCYWRQVSDAYGDMRYMCPGLYISSELEHRGVQGTWNYRPVVNISTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWC0</accession>
    <name>A0ABR1VWC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_010190</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666467.1">
        <property type="nucleotide sequence ID" value="XM_066814505.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047565"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="9">
        <location>
            <begin position="307"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="409"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="450"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="467" mass="49868" checksum="FFBC2C5F1CD331E4" modified="2025-10-08" version="1">MAQLFLHDTGTMAFPNLTVAGSVDVVDAAIFANRLETVSDLKVEYSRGAFLSNFKALKSTTGNVYAGNGSIANGLFRVWIPGPNHTRSGDLNITKNSGLSEISFNGLTDVKRLYVMDNPDSTVPGDFSRLTAADYIYVNGRMNNTFPLFPHLSTVAEARIEPWNADFDCSSLVKMRDTGKIGVLFCNGTNGINGLEASQSGLSTTASVGIGVGIGALVIIAALVWLAAYYRCKLRGLRRESHNSGRDDPKEIVHGVIKPTGARLGDTHIREAGAIAHNHTVQLEQSNTRSTPPDLSAVPTTTKMGDPYTLLGCYVDQSPNRTLPTTAYQRMPTNRATVCHALCNAPEYRATLFGLEYGAECYCGAGDPASFQKAASDAECDRPCPANASEMCGGDWRLSLYRIRDTTLDPSPAVTAAPPTGPSSSAGSGSGDDQHTDSAGGKQNLTGAKSPGSVWRRSSSWRSWPGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWT8</accession>
    <name>A0ABR1VWT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">tRNA pseudouridine synthase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009263</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665540.1">
        <property type="nucleotide sequence ID" value="XM_066813578.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046638"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02568">
        <property type="entry name" value="PseudoU_synth_PUS1_PUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041708">
        <property type="entry name" value="PUS1/PUS2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF4">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="5">
        <location>
            <begin position="471"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="354"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="651"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="363"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="662"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8074600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="681" mass="75682" checksum="B48776A5321B1D29" modified="2025-10-08" version="1">MGIEHDTTASAAPAPAPVASSGSADNSKPTQTVQSGSDGSALPDAGGNESRGDRKPKNGRFDNKRGRGRGGRGGRGGGGGGRGGKDNKEGGDNKRRDLGRNEYGRKRTDKRGRNDDWQDTKRRKVGENGESVGEDGEPRESARDKPSYMSIPFAEEEIAAEERRPKRKVAVMIGYAGTGYHGMQINHREKTIEGDLFAAFVTAKAISKANADDPRKSQLIRCARTDKGVHAAGNVISLKLIIEDEDIVQKINEALPPQIRIWGIQRTNNAFNCYQTCDSRWYEYLMPSYCLLPPHHESFLGKKVLESVKENGVEDEYATKLGDLKDFWYDVEKNDIQPILESLEPEVREKVMRRLFTPEDESPETKTEKTAKKDNNTAATSEAPVENTEAAAETIPDAAPTSTTTTEQPDAEMKDAEASAPAPQEKTTEEVKPPKEASPVDVAVKQIKAAYVAAKRRYRTTPGHIARLQEALNQYLGTRNYHNYTVQKAPSDPSAKRHIKSFIVNPQPIQINDTEWLSLKVHGQSFMMHQIRKMVGMAVLLTRCATDLSRIEESYQPGRISIPKAPGLGLLLERPVFENYNTRAAESYDRPKIDFGNYEKELQAFKDSHIYQRIFDLEEKENSFHAFFHQIDNFKTDYFLWVTAGGMGAAHKRTGQGEDVPEGLKKELGDDGKGGEIVEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXX7</accession>
    <name>A0ABR1VXX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bactericidal permeability-increasing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665975.1">
        <property type="nucleotide sequence ID" value="XM_066814013.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047073"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017943">
        <property type="entry name" value="Bactericidal_perm-incr_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045967">
        <property type="entry name" value="HAM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF4">
        <property type="entry name" value="DUF5923 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19343">
        <property type="entry name" value="HAM1_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55394">
        <property type="entry name" value="Bactericidal permeability-increasing protein, BPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAM1-like N-terminal" evidence="2">
        <location>
            <begin position="28"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like N-terminal" evidence="2">
        <location>
            <begin position="192"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="725" mass="82169" checksum="FFEB194A1650F4C4" modified="2025-10-08" version="1">MLSSCFGWGKGSDAEREPLLPQYEQDTHLQRELQRKLHSYQMIRALTRGYMPSTEQTIINLRTLMASDVLNPDNPDLSDSGKRLVRLTKQWLHQFIALLRNKNSQDQLQDLIWFLTKSRISVDIADLQARAQKSKAKADAAAAYKSLQTVGSLLFTNRDFRVFLGDLSVEAGKQLEPSAEEQAGVAKADGPATNGKTPSGQELQGEVDDVADIVAAKGKDVAHAAVESAEDKLSGDEGKNLLKRLQQVVLNLRKRTDYSDSVSTLGLLIKRYAIVYSRAAEEIAEVAQDDVHENQETDRAMKNTWAFVTSFGDKKEWDRCEELFKKVMAHKDKDPEFEHFIQELGDSLQRLLTDPEFFNDADKKLKDLREESKKIGTEGSLRHDADELLQQLSVTYQSILRDEDVHNLMTTTLRIFGVLSPTNTATNPDLIQDALRVFVPLAISAIQYLPIPRLEVSTPHIDLLLENLIVEPGKTVNHTSFLPYRLKIENYNDFEIRKARFRTATSTTNLLLIKIDGLSCRADEMGYWLRAHSGLLRLADQGIAGFALDERGIDIHLEVEVCRERLEQILTLKAVRVRVHKLNYSLKKSKFSWLGWLIKPLLRPILKATMEVQLASAISEFLHAANRELLYARERLRATRISNPDDLMTFLKAVASRILPEEDPNLYTRVGVDEPGKGVFKGVYTPASVAKLWHEEAEQAKDRIEEYEIGGWRNEVFDTHVRVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY44</accession>
    <name>A0ABR1VY44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF2306 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666050.1">
        <property type="nucleotide sequence ID" value="XM_066814088.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047148"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018750">
        <property type="entry name" value="DUF2306_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10067">
        <property type="entry name" value="DUF2306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="38847" checksum="5D8727501A74DC9D" modified="2025-10-08" version="1">MGEPSRPPANGFVAAARKVYHPVGFSKGYNFVLWFIFGGAFLGFILARLPYFNFYGVFCSPDASATLGALPGECYYYLHFDRYKVGVILHLAGILPAGLLACLQFTPVVRYKALILHRVAGWLAILLSVIGIAGALMIARRAFGGGIESQTITGVMAIAFLVSLLLAVVNIKRLQIEEHRKWMLRAWFYAGAIITMRIILVIAAIIIAPLGGYYTAMPCAKVAFSVGSDEQTLQDYPACAPYFNGTNPDQWTMITANFNGTDVAQIAAALDMTAGMALWLAFLLHAIGVEVYLHLTPAEHNRLRAVSYQRQLAAGMRNPGRAGLTADRLGDAEQWTLPEAKAEKVQAETSKDSLPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7T8</accession>
    <name>A0ABR1W7T8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MoaB/Mog domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667014.1">
        <property type="nucleotide sequence ID" value="XM_066811672.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044732"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056596">
        <property type="entry name" value="FLAD1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47675">
        <property type="entry name" value="MOLYBDOPTERIN BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47675:SF1">
        <property type="entry name" value="MOLYBDOPTERIN BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24102">
        <property type="entry name" value="FLAD1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaB/Mog" evidence="1">
        <location>
            <begin position="16"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="293" mass="32650" checksum="60A449EB1AFDCC16" modified="2025-10-08" version="1">MATADERNTRTIHTAACLIIGDEVLGGKTVDTNSAYMAKWCFNLGMNLKRVEVIEDNEEEIMEAVKRMSDRYDFVVTSGGIGPTRESSHDDITYQSIAKAFGLKLILHEEAYQKMKKLTKPRKDEPNFSWDVESPQKTARLRMVRLPIDESRDLSKQALFPQDDLWVPVSVVNGNVHILPGVPRLFQALLEGLKPFIVDRLVDPEGKGIIRVIISTPKAESSVASYLTELAEKVAPKGVKVGSYPRWGKKNNSVTLVGRDREYLESLVPEVLAAVDGKRIATESEDDEPAPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8B7</accession>
    <name>A0ABR1W8B7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4-carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667194.1">
        <property type="nucleotide sequence ID" value="XM_066811852.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044912"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052512">
        <property type="entry name" value="4CMD/NDH-1_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33570">
        <property type="entry name" value="4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33570:SF2">
        <property type="entry name" value="CARBOXYMUCONOLACTONE DECARBOXYLASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxymuconolactone decarboxylase-like" evidence="2">
        <location>
            <begin position="46"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="184" mass="20187" checksum="38DA84571834EFDD" modified="2025-10-08" version="1">MSTSSNFDELHKQLFEEGVKVRRAVLGDEYVDKALQNATPFTMPGQELITEWAWGTVWQRPGLDRKQRSLLNIGIIIAQKAWLELALHTRGAINNGLTEVEIREAVLQATVYCGTPAGVEAMMVTEKTINEMIAKGGIQAAGMSRGAVGSRTGERMRRGRVVHDPPPLGRVRRGMGEVLGHVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8H6</accession>
    <name>A0ABR1W8H6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carbamoyl phosphate synthase arginine-specific small chain</fullName>
            <ecNumber evidence="3">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Arginine-specific carbamoyl phosphate synthetase, glutamine chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Glutamine-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_007605</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667262.1">
        <property type="nucleotide sequence ID" value="XM_066811920.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044980"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="entry name" value="Carbamoyl-phosphate synthase small subunit, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009475">
        <property type="entry name" value="PRK12838.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF4">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE ARGININE-SPECIFIC SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="Carbamoyl phosphate synthetase, small subunit N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbamoyl-phosphate synthase small subunit N-terminal" evidence="15">
        <location>
            <begin position="63"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8079787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="463" mass="50424" checksum="DAC8548FEE8A21FC" modified="2025-10-08" version="1">MFSRIATRACKPAAFGAAAGLKPQPRCFSVTAASLANRAAALGSKGRQMPSTISRATEPVSGVEATLTIRDGPVFRGTAFGANANISGEAVFTTSLVGYPESMTDPSYRGQIIVFTQPLIGNYGVPSNMRDHYNLLKYFESPHIQCAGVVVADVAEKYSHWTAVESLGDWCAREGIPAISGVDTREIVTFLREQGSSLARISIGDEYDADEDESFVDPGQINLVKRVSTKAPFVVEAPNPKYHIALIDCGVKENILRSLVSRGASVTVFPYNFKIQKVADNFDGVFISNGPGDPTHCQETVYNLRTLMETSQVPIMGICLGHQLLALAVGARTIKLKYGNRAHNIPALDVTTGQCHITSQNHGYAVDASSLPKEWKEYFVNLNDGSNEGMRHTSRPIFSTQFHPEAKGGPMDSSYLFDKYIEDVMAFKGTQQVYKDNRPSQLMLDIMSRERVGVQPEPLANAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8K1</accession>
    <name>A0ABR1W8K1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peroxisomal hydratase-dehydrogenase-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_007631</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667288.1">
        <property type="nucleotide sequence ID" value="XM_066811946.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045006"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05353">
        <property type="entry name" value="hydroxyacyl-CoA-like_DH_SDR_c-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051687">
        <property type="entry name" value="Peroxisomal_Beta-Oxidation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024:SF2">
        <property type="entry name" value="SCP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="10">
        <location>
            <begin position="315"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="767"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8079813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="913" mass="98474" checksum="9C576A6F00ACF624" modified="2025-10-08" version="1">MADQLRFDDQVVVVTGAGGGLGKAYATFFGSRGAKVVVNDLGGSFKGEGNSTKAADVVVDEIKKAGGQAVANYDSVENGDKIIETAIQNFGRIDVLINNAGILRDVSFKNMSDQDWDLIMKVHVKGAYKCARAAWPYFRKQKYGRVINTASAAGLFGSFGQCNYSAAKLAQVGFTETLAKEGAKYNIICNVIAPIAASRMTQTVMPPEVLENLRPEWVVPLVAVLVHKSNTDENGSIFEVGGGHIAKFRWERSSGLLLKADDSYTPGAVLKKWNKVTDFSDPQYPSGPNDFMSLLEDSMKMGPSDKGEPLDFKGRVALITGGGAGIGRAYSLAFARAGASVVVNDLVNPDTVVEEIKKMGGKAAGVKASAEEGEKVVKGAMDAFGRIDIIINNAGILRDKAFTNMDDNLWDPVLNVHLRGTYKVTKAAWPIMLKQKYGRIVNTTSTSGIYGNFGQANYAAAKCGILGFSRALALEGYKYNIYTNTIAPNAGTAMTATILPEELVQAFKPDYIAPLVLALCSDKVPKNPTGGLYEVGSGWCGQTRWQRSGGAAFPVDVPLTPEAVRQQWEKIITFDERADHPEKAADAVGKVMANMENRSGAAKKQKKPSPAPLPESEGKKYLDAIATAQNAKSPETEFSYSERDCMLYNLGVGAKRTEIPYVFEGHEDFQVLPTYGVIPAFDVNTPYSMDQVVPNFNPMMLLHGEQYLEIKKYPIPTAARTKSYAKLIEVVDKGSAAILKGGVLTKNAETGEDLFYNESTVFLRGAGGFGGQRKPQDRGASTAVNSPPKRMPDVVVESTTTEEQAAVYRLSGDYNPLHVDPNFAKMGGFKRPILHGLCFMGIAGKAVYEKFGPFKNIKVRFAGTVLPGETLVTEMWKDGNKVIFQAKVKETGKMAISGAAAELVDGSSSSSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8W7</accession>
    <name>A0ABR1W8W7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-guanine(15) transglycosylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007746</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667403.1">
        <property type="nucleotide sequence ID" value="XM_066812061.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045121"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="2">
        <location>
            <begin position="173"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="377" mass="40921" checksum="EA5123D920CED329" modified="2025-10-08" version="1">MAATIASQSSAALKFDLVARCSTTRARASCLTLPHGPVQLPMFMPVATQASLKGLTPEQLEETGCRLCLNNTYHLGLKPGQEVLAAIGGAHKLQGWQHNILTDSGGFQMVSLLKLANITEEGVRFLSPHDGTPMLLTPEHSISLQNTIGSDIMMQLDDVLVTTSPDAARMREAMLRSCCKEMIARDTPGIAIGGLSGGEAKADYCRVVATCTELLPELKPRYVMGIGYPEDLVVSVALGADMFDCVWPTRTARFGNAVTKHGVLNIKNAKFAVDFGPIEEGCGCICCRKGDGGLGITRAFVHHNTAKETVSAHLLTLHNVWYQLNLMREVRDAIMADQYPAFIRRFFANLYPNKADYPEWALGALRGVGVDLVEDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9C3</accession>
    <name>A0ABR1W9C3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_007912</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667569.1">
        <property type="nucleotide sequence ID" value="XM_066812227.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045287"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF3">
        <property type="entry name" value="NUCLEOPORIN SEH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="292"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8080094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="428" mass="46822" checksum="64FF9551E3C29732" modified="2025-10-08" version="1">MSSTPALDGAPPPPQENPAFHLIAHGNHDIVQAVAFNAYGDRCATGSVDGKIRVFNRHKDGIWRLCDHWSAHGSEILELQWLPPTVYPNLLASLGIEGHFKLWTEDNSAPPGRRFSATGKAAYETRSPKSPYRSFSIKHNEDTRHTYFALLAADGKLSVFESEEPETLADYTAIDEFQALPKPSRGEETCFKVRFDPNPEPCYTALRAGVPIDALGLVVSGLMTARVFRTRETITGSFGAATRAREFYQAAEITGHKGLVRDVAWAPGNFRGYDMIATACQDGHSWRVSDVLGKSTHEESRSSSTSAATSAVAHASSRAAQAQAHAHHSGIRAEIDKSGTQGDRKYLGQPGQVAHTVRELCKLENMTRYGDHRSPVWRVGFDDDGQILGSVGDEGKLMCYRQKPDGAWAKSSELAPMKAKLVVPHVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9H4</accession>
    <name>A0ABR1W9H4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Long-chain acyl-CoA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007959</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667616.1">
        <property type="nucleotide sequence ID" value="XM_066812274.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045334"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="111"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="701" mass="76686" checksum="11C37D46004025E1" modified="2025-10-08" version="1">MGDWQDSKYRTLPLHPRMSAKGPYSIETPECEPVEGETIPRRHPLTADGLISQPADNISTIYELVRVSAEKYGNAKCMGSRRLVRTHQETKKVKKMVDGAEQEVDKNWTFFELSSYEYLSYNDYEKLVLNVGSGLRKLGMQKEDRVHIFAATSAHWLAMSHGAASQSMPIVTAYDTLGQEGLRHSMVATGAKAIFLDPHLLPTLGNVLKDATDVRYVIWNSQNQVKQEHINNLKSSFPNVTVLSFKELEKMGKENPSEPVPPHPNDLCCIMYTSGSTGTPKGVPLKHSNVVAAVAGVSVVVQPFIGPGDGLLTYLPLAHILEFVFENAAIFWGTTMGYGNPKTLSDTSVRNCAGDIREFKPSVLVGVPAVWESVKKGITAKVAASGGVAQKLFWAAMWAKSQLMSAGLPGSGLLDAIVFKKIKEATGGKLKLCLNGGGPVSRDTQHFISMAIAPMIIGYGLTETNAMGTLMNPQEWSADSHGAMPACIEVKLVDFPDAGYFATNTPNPQGEVWIRGPSVMREYYKNEKETAEAIATGGWFKTGDIGEWDKNGHLKLIDRKKNLVKTLNGEYIALEKLESIYRSASFVGNICVYADQQKAKPIAIIVPLEPALKKLAHSIDIKGDSLEELVHNKKLQNAVLKELQNAGRQGGLSGIEIIDGVVLTDEEWTPQNGLVTAAQKLNRKGILEKYKKEVDEAYGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9P3</accession>
    <name>A0ABR1W9P3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosyl-L-methionine-dependent N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008034</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667691.1">
        <property type="nucleotide sequence ID" value="XM_066812349.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045409"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041068">
        <property type="entry name" value="HTH_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18558">
        <property type="entry name" value="HTH_51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS/mFAS DH" evidence="8">
        <location>
            <begin position="523"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="875"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="523"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="680"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="963"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="965"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="555"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2354" mass="261631" checksum="84C68B103A05A3D5" modified="2025-10-08" version="1">MAVPRQLTPWKSSRQVACVNSYGAAGSNSVVMACGPPTPAPIIRTNASRAGMPSKLPLIISAATKSSLSQYCQKLLDWLQVNRSPESPDTQIADVLFNLADRANRSLEQNLLASVSDIDDLKSKLSAATREDNSAFITPPLPKPVVLVFSGQESQYVGLSESIPATLDIFRHHLDECQDLLVHYLGLEGLYPAIFQRTPISDIVTLHAALFSVQYASARAWMDCGLRVSAVVGHSFGQLTALCIAGALSLADAIRLVTGRAALIKTHWGAEPGCMLAIQGNRQRVKAFLEQVKDKTDYAEIACLNGPKNHVVVGVSKSIDKIEALVAEEGQRDGIRAKRLPVTHGFHSAFTEALLPPLEDLASELQWNNPTIHLELCEEASRDQKLDHRSIAQHTRRPVYFQQAIERLEDRFPECVWLEAGRGSSVTQLVRGCLKSPERHSLHAPQLATPNSLDSLVDVTVKLWKEGQKVQYWQFHPSQRLQYKTLSLPPYQFQKTRHWLPYVVPKMTDNKTAGGQPDEPQRHELMSLVKGGKVGEAVFRISPKSERFKTLVASHVMADRAAMPASLYLEVAARAGLLLQEDLSATTWVPTVKDLVMKSPIGLDPESEITLTMKRLDGPSPTWSFSILLAGPGCNKAQETTTGVVHLNKSTDTHVAQTFKRFETLIGPARWEGILQHRDAERMQGKHIYRAFSQIVQYSDLFKGIKTISCLGGEAAGEVSITPDPNDAADQRLTDTPMADSFMQFAGFLSNYFNEASTPSSLFVCHHIEHLEFGPAFSPDAGRWFVFASMTDSSEEHTSVDVYVFEAQSKKLVLTVLGMEFSKISCSTLARLLDGASSAEKPKAPFDHGSDLQKFAVPDNVSPTSNTRTSAVATEASNTKRPEIFQIIANIADVEIDEISGGITLPDIGIDSLGVTEMISDISSILHVDLGLSTMLTLADIDALVAHIDERLGLHAVPSTGSAAECREGSKSRAFSREPVAEPSQHALEKKDERMSGINEKNSIPVGPTIASAYDAFNAVRLSYDGLAADACALDYWNEIYCDDARLMMAYITEAFAKLGCELRKLRPYEAIPRLEKVLPRHRQLMHQLHLFLADERAILASHQAPSGFVRSDSVIDETPGELVYQQIIEKHPLNATVRHLIRAVGSQLAECLMGQSDGLQIVFGNKTNKKTLEDLYENWPMLVAATKLLGNFLHHAFTGNNNEAAGRPFRILEVGAGTGGTTRYIVDFLQKHGIKFEYHFTDLSGSLIQKAKRSFKTLVPDGTMTFGVLDIEQEPPAEFLEAFHVVISTNCIHATRDLARSLGNVRKMVRPDGAVALIEMTRTMYIFDIIVGLLEGWWLFEDGRSHALADEARWTRAMLDAGFKEVLFSDGESEEAKTVRVIGGFPQSAPAKPHAESKNPEGVPKHTPFTVQEVVYKTIARQDIHADIYCPENADPARKMPIALMIHGGSHILFSRKDIRPPQTRIMLDMGLLPVSLDHRLCPEVALAEGPMVDVCDALVWARTMLPNIPLKNRNIIPDPDRRGLKPPDAILAFYSPTDYEDDWWQSPIQPIGAEDWGMEYDVLEAVQNEPITNYGVVGAWAPLSDPRIRTDPRCRIVLHINWKAQTLPVIIRGLPSRARADKEKHVSDAGAKDWNALPQPSVEEIRRCSPLAQVRAGKYATPTFMIYGTADDLIPYTQSVRTVEEMKRRGIDAQLVLVPDAPHVCDMSNDPESAGWKAVLKAYKWLEFMLVHNHIDFGVDVLKGDSHAAIVDILMPDRAFSPLLKTNSNMRLINVHTYELHEFWGNQVPKYAILTHTWDGEEVTHQEWLAWLASACPSVANKKGFQKIMGACERAKEDQLTWLWVDTNCIDKASSAELSEAINSMYAWYRDSTICYCYMADVPTPSGDHTELLSSFRRSRWFTRGWTLQELLATSRLVFYSRSWTSIGTKTSLSSSIAAETGIDMACLSETSGQDSIRQASVAKKMSWLARRETTRVEDIAYCMLGLFEINMPLLYGEGMRAFTRLQEEILRSTNDHTIFCWTWNEQVPSNWVSMLAPAPGMFKDSAYYVTKRAPGNLAPYSITNLGLSISLPVLYTLSGVYAALDAGPSQDGPDKRSYIHLCRISQGSMIFERSRFPRRPVALETGNPANWCRRHMIVQSKPEFRPPPGSDPKPPAKLGLFLLTDEEVFFERFEETETLGDSPVCIHRTLTFPPGLLDSKRNILFLSPPSPEAKDGYHTALVAIQAHSSRGGWYLLFFAASVRESGTYWYSSATQTRHLPKVHPFLHHILGDNGGPSEDYKVDLEVVYDYLRTKVAKSWDGLQNYGRQDVHFHVGIGDELEVSSEMVVKVAALRTEDCYYKDAPHPCLVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9Q6</accession>
    <name>A0ABR1W9Q6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667681.1">
        <property type="nucleotide sequence ID" value="XM_066812339.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045399"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="76" mass="8734" checksum="FDB9EEA71F3C7490" modified="2025-10-08" version="1">MMETLSTNGVCKRKQGSKELTDDEFDSEPEPEPGDIHLLNRDGDGERHEPEYSRQKKLLSHADSSPPENPDRERRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9W0</accession>
    <name>A0ABR1W9W0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS multidrug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008113</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667770.1">
        <property type="nucleotide sequence ID" value="XM_066812428.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045488"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF193">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G00940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="537"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="69"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="569" mass="60886" checksum="EAEEF1106BD7CE42" modified="2025-10-08" version="1">MQPASKPDIPTQQHQGRKMVEEPIPLTDFSLNREPNSDVGNGPPAVVSPANSEEEDGHAWVSGWKLGIIITAITLPCFLLLLDTSIIVTAIPQITDDFRSLPDVGWYAAAYMISSAVLQPLTGRFYTSFNSKWAFVSFVTLFELGSLVCGVATSSTMLIIGRAVAGMGGSGIVNGAFTIIAGCVPMPKRPPLIGFASGIAQLGLVTGPLIGGVLTEHATWRWCFYINLPIGGLVLGLIAFVHVPDEVPKAPPLSVFRTLPSNLDFIGFTIFAPSAIMLLLALQWGGNTFAWNSSQIIGLFVGSGATFFVFLAWDHHKGDDAMIPFSIIRQRYVWASSLTYGFFMGSVFCASYYLPIYFQGVRDASPTMSGVYILPSVLPNILFALAAGWLHGRVGYYLPFSLIGAILVSISNGLLSTLSPATSTAKWIGYQILGGAGRGIGMQASIIAVQNTVEPSQIPVAMAFVMFSQAFCGAVWLAFCDLIFTNGLRALIPVYAPSVDPQTVIDGGARSLSAGSEIDAEAAWGILVAYAKTVDRVFYFAAGLSVASFVLAWFQGFKDIRKKKQVVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA81</accession>
    <name>A0ABR1WA81_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008232</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667889.1">
        <property type="nucleotide sequence ID" value="XM_066812547.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045607"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="606" mass="66954" checksum="E695478D8EFAC2C8" modified="2025-10-08" version="1">MGRLSRGCFKCRQRRVRCDQGRPSCQHCIKRDEVCEGYRDEATLIFRYETEKVLQHARVAAAGNYSATPASIGSCRRSRSADGRSRPVSSEGSPDSSSLTPVEATSLLNLPSPYPWLKQIPRNAQVRKEDRAVEQFMDKYVLYPCNETSSPGFLEHLPSLFKEVNIEGRYALRWAVRAAAYAEVARDSEGSHVAQKALHCYGEALSALGESLAEPGKTPDDYDLMTIVVLDLFEALFLPDISQVGAHTQGMAQILRLRGSDQFYNPRGWSLFRLAHHRIQKHQLAFNQPALSESTIWLDQLNDRVPFVRMEKDAHEIKQTCERARSLLENAIEDGSVHSVESLQELYELDQTASSWRQGPQWQFKSVSASELSSGLPFPPLTRIVELHGDVWKAYELNYHRTARILFHQQLLKVIEAVLAKPDLPELVVLSLHEMMDRSTTAVCALVESILATVPQSLGDVDHLGHVAEAPSAAPKLLFLNLDTYLTSGTTYTSVMLAISQLLVAVLAVMPALALPTASPNGVSLPERPSRSTLLSGPHAVPMATAPVVRVSAEEVATASLGPPELDTATEVTHSPLRLLFAHGMTIYFEAAEASLISSLLSNKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA92</accession>
    <name>A0ABR1WA92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor A domain-containing protein 5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666860.1">
        <property type="nucleotide sequence ID" value="XM_066811518.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044578"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="23331" checksum="6DC2D12BEB9F70E0" modified="2025-10-08" version="1">MAISPPAQPQTGSAFGSTNPGSNSGGGLFGGVSSPSRAQANNVPFGSATAGSDSGSYSDGRPVPVYEMAASSSEKENQYYYREDQGSYSDFHPTQPKPTLSSLVLLQSFEGSWPWSQELCSAMQWDEASLTSSFQADFAAKYGDEGGSVGQNPDVIATICVIAWLRKECAGEKDSWELVVDKALAWLAVQLPGKDIEGLVEMAKALVVHQRYSIEIEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAU3</accession>
    <name>A0ABR1WAU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007459</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667116.1">
        <property type="nucleotide sequence ID" value="XM_066811774.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044834"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045915680" evidence="2">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="98" mass="9826" checksum="C1A64EB682F3206F" modified="2025-10-08" version="1">MHAPSVAQLLACGLATTAAFQLPNTAFSRRSAGVIAALAAPAAAAPAAQSSGAAPSAAKSSGAAPPLPKHPAPHHLPKRPEPHLPPRLLPFWSRTACC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAX9</accession>
    <name>A0ABR1WAX9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phosphate:H+ symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008482</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668139.1">
        <property type="nucleotide sequence ID" value="XM_066812797.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045857"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17364">
        <property type="entry name" value="MFS_PhT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004738">
        <property type="entry name" value="Phos_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00887">
        <property type="entry name" value="2A0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="518"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="60"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="550"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="571" mass="61655" checksum="EE41EB9E5E5164DD" modified="2025-10-08" version="1">MPGELETPRAPAAVTKTSGGNAAYHNYHNDFLHIQDPNERRRLALAEIDAAPFGWYHVRAVVVAGVGFFTDSYDIFAVSLLTLMLGIVYYPSAGSMPSSSDNAIKLATSAGTVIGQLGFGYLADHVGRKKMYGLELIIIIFATVAQALSSNSPSVDVVGLIIFWRVLMGIGIGGDYPLSSIITSEFATTKWRGAMMGAVFAMQGLGQLCCAIVMLCVTAGFKQSLSPSPDTKHCSGDCAIAVDKMWRVVIGFGAVPATIALYYRLTIPETPRYTFDIGRDVEKATDDVKAYMSGKSEGKPDEVSRIQARDAAQTQMQIPKASWSDFIRHFSIPKNGLLLLGTAGSWFMLDVAYYGLSLNNAAILKIIGYSTKNLRTYEVLWNTAIGNLIIVLAGAVPGYWVTVATVDTLGRKTIQMGGFIILTILFVVMGFGYNYIMAHSQNGLLAIYVLAQFFFNFGPNATTFIVPGEVFPTRYRSTAHGISAASGKIGSIIGQGAISTLKSRGATPENDSPWLDHVLQIYALFMLLGCFTTLCIPETKRKTLEELCGEDQPAPLPASANSNEAKHTESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB15</accession>
    <name>A0ABR1WB15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668108.1">
        <property type="nucleotide sequence ID" value="XM_066812766.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045826"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF16">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="15"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="256" mass="27784" checksum="47C74BA6D0DA204D" modified="2025-10-08" version="1">MPFVPSPTFHLTSPRLYISHFHAPQHNQFLVDLYTSELYTKHNKTNVDTPEKAQAQIENWMPGWHERNGYGPYVTSLRFARDIVVEGGDSTAADNDDNEKPAALLKPGQVPIGIVTLMRGAHYTVPDCGFALLPAYAGKGYATEAGKRIIKYATDPKPSPTSEVASAASADDDNDVPREGEGLGLEGVFGFTSSDNADSRKVCQRIGLEFRGIYPLEAFGGEMSAVFVLPGMQADLSVYGIKAARTDITVRESPGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBG8</accession>
    <name>A0ABR1WBG8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Efflux pump FUS6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008667</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668324.1">
        <property type="nucleotide sequence ID" value="XM_066812982.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046042"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF195">
        <property type="entry name" value="PEP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="532"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="577" mass="61659" checksum="8D6FD3F23BDBE357" modified="2025-10-08" version="1">MAVEEVSLNLEGVSSSPNSSPNVENVAGDERPRPRLHLVTYLAVVSVNLGFVAQNFAITGAGTQAQIIGQTFHSSDTGWTTGVIVIFCVVLGPIVSQCADLWGRKWFLVVLNAFGFVGSIVVARASDMPMAIAGFCVIGLSFGNQGLIHAVSGEVLPRRWRSWGQAAALVSTEIGLVLGLVVAGSLNRTGGADGFRNFYYTTAAFYFAATGLCILVYNPPPTRQQVEVVGSKLAKLDWLGFLLLAASVVLFSIALSWSQNPYSWDDLTGHVAAPFALSIALVAVLVVYERRKPDGLFHHGLFQNRMFPICLVCVFAEGISFYAANVYVPLQGSVLFPDEDFLYAPLRLAVGFVAAVMASVGTGLYCFLTKRVRWVTFVALVIFVAFFAGMAGALRGIDGSDLSRALWGLPVILGVAFGMVLVTLVTAAQLCVPASLVTISSCLMLSIRSLGGTVGFAVYQAVYQSAMSHLDENIAQAGIAEGLPQESVPDFVSYAKERDKSDLPSIPGMNESIVEAGAVALRSTYKSAFYNVWVTGAAFVSAVAVLLVSVSIFMYDPTSEFTNHIDYPIEKEVDPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC65</accession>
    <name>A0ABR1WC65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sec7/BIG1-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668565.1">
        <property type="nucleotide sequence ID" value="XM_066813223.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046283"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sec7/BIG1-like C-terminal" evidence="2">
        <location>
            <begin position="195"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8081090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="410" mass="45669" checksum="12CEA67839EE5092" modified="2025-10-08" version="1">MIQALRNMIVLFTHFFDALEYMLDRFLDLLALCICQENDTIARIGSNCLQQLILQNVLKFNAGHWNQIVGSFCELFERTTAYQLFSATTINAPSALSPPPNGLGFEVPLTPTDDTEEGNALSINGTDKNGQPSESETKSGSPASAATDDESLRTPTMSAATPLEEFKPSSSLQQQPVVVTAARRRFFNRIISRCVLQLLMIETVNELFSNEAVYSQIPSAELLRLMALLKKSFLFARKFNNDKELRMRLWREGGSAATYIQILFRMFADTSPSRAESRPEVEKALIPLCKDVIKGYLALEEESQQRNIVAWRPVVVDVLEGYSVWPEKEFEEHLRAFYPLVVELLGKEVSPDLRGALLMVLRRIGEVALRIEGMTGGRRDSVISVAATETPGGELGHGGEEGEVGMRMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCH7</accession>
    <name>A0ABR1WCH7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667308.1">
        <property type="nucleotide sequence ID" value="XM_066811966.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045026"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="614" mass="69129" checksum="FE2650EC8595BB1A" modified="2025-10-08" version="1">MAPVKRSFDDSSASPVEETQPSKKKKPCLDKFTQTDAKDLKKHIKKDTKKDTKKDTKKDTKMPSTSITTSAVSGEGSPAKSSPAPAAKQEAKPVAEPTCGDKRKADEVASEQPDSKRSRPSSPVPETPSSPAPSGEEEKKKKKKKRPNKKRKNRNQFTSADEPLLQQVIDGTVPEGTNVPDRVRRAIPDVSLRIIHNERVGDHRWDAQEELSFQRGGTEAKKVGDRPLPIYHAIASAAYSDELIERMMKDYMAVHKSAVDGIWGKRAHGKTYPPPLWWAIIHGRLEVVRRLLKLGARPDKVRFGNLEHLQGREPFTSPCKWEHVGHERCSPPRARWCCDMYNYLAWSIDRLLESRPAGAHADFDARMDEVECCMMWVQGTRSDWMPAYDSSGTAGRTFFVEPLINAGFFKLLRRFEVRDGMSAVNARKLLDHFVRDVAWSRKTADVLCWFRKLPPGRSVRTESRDFQAMLEQFAVRLADLRPGDELVQGEFGLADAYARVDAILAAWEARIPRLFELDEFSAAASFQTYRGWAAELVAVDGAFWKWLAQFAQFAPEKLLSLRKNANAIMHWQKLVTEWAEAQTPLDTKKEDATTDEQKTGDDTKDAATGDAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCR0</accession>
    <name>A0ABR1WCR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Variant SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008119</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667776.1">
        <property type="nucleotide sequence ID" value="XM_066812434.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045494"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11854">
        <property type="entry name" value="SH3_Fus1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035521">
        <property type="entry name" value="Fus1_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="407"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="118"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="247"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="364"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="461"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="604"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="629" mass="65599" checksum="5907A860B293328B" modified="2025-10-08" version="1">MPNHKHFHRRSVGEKWDDIKRDIKNIANELTHKSPDQAQIEIRAPAPSTVFKTVFKTMAPTFTGEIGGYVTMSSGADGNPTAQALPSNGGGVLPESLVPTSAGAFSDHTGLAIETAPTTARNQASSTLDPAANNVATPSASSSAASDSSSEGGGAAVKAGIAIGVLGGLLIIGLAVFFLFSRRRKQMEKERAAAEAEKSSPRSAAQQLQRPQPTTANLRFTRRTPRFLPEFGERRSSKGAAMALALGPAPSNSQANRPAGQSPWERPMTAQSNSQENPFGDHAEHYDGASRSATMEQPNNPFDAPEHVVGVAQTTDAPRQAPNGIAAAAAAAAAASGAGLARKQSVRKDVPQPLDLTRVNEAPLPLPSLVSQPSPTGTEFSFTSVAPGQSPGPSQSANAIAAAGGPAHSTVHRVQLDFKPSLEDEMELKAGQLVRLLHEYDDGWALCIRLDRSQQGVVPRTCLSTRPVKPRPAGGPPGARNGPPINPNRGPGGAPRGQRPMTPQGGRPQSPAMMGRPQSPAMMGRPQSPAMSRPQSPAMRGPQSPAGMRGPQSPGGPMNGRPASPGPRPMSPAGARGQSPGPRQRNGSESGKSARRMTPPGPSPLQQQQEQQQAPPRPVARKPVPGQAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCS5</accession>
    <name>A0ABR1WCS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="7">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667429.1">
        <property type="nucleotide sequence ID" value="XM_066812087.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045147"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="335" mass="36041" checksum="A9161ECB7E6D59F7" modified="2025-10-08" version="1">MADLNLEEIRDTLVSVAYEAGRMILSANPTDIATDTKLNCESHISPNLSKAYLKTQQYANSLSVAAVDIVTETDKAVEALVSGQLQKKYPTFDFMGEETYKPGQKLTASPTFIVDPIDGTTNFVHGFPSACISLGLAVDRTPTIGVVYNPYLDQLYTAISGRGAFLTHGRAWGIPSEDGGPDKGRVSRLPLSRNPPPLAGLGAALVAVEWGSSRDGVNYEVKTEVFRKLCATTETGGAMVHSLRSLGSAALNLCAVAAGQLDAYWEGGCWAWDVCAGWTILAEAGGVMAGGNPGVWEPQLDDRKYLAVRGGAAPEQQKELVRQFWEVMGERKMEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WD95</accession>
    <name>A0ABR1WD95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008253</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667910.1">
        <property type="nucleotide sequence ID" value="XM_066812568.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045628"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF33">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="139"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="580" mass="63316" checksum="8CDCE7C4AD579826" modified="2025-10-08" version="1">MARNPDIEKAGEQSRASGTADGSDMFSANESASVEGSSTDDKAGEKRVEGVGQEGNASIASGYPDSDQYDEIAPVASHASQASRRSRFSRILSKKSSKKDELPPTLLPLTDLDRGVIGWDGQDDPKHPQNFSRSRQYWIIILLALVTFMTPLASSILAPGIEYYSAEFGNPSTTLGAMPVSIYLLGYAIGPLFLSPLSEIYGRFIVLSCSNVFFCIWFIGTGLAPNLASLIIFRLLNGIGGSATLTLGGSVIADVFPVERRGFAISIWTIGPTMGPSLGPVIGAFIASTIGWRWTSWIVMIPSTVATVLLIILLPETNSRVLMRRKVTALRKELNRPDLVSCYETEQSRTLSKWAVIRQGLTRPLKFLFLCPMIAILSLYISFVYGTIYLMYNTVAPVFEGQYGWGTGVSGLPFLAMGFGYGVGLVTFSFWSDRVVVSRTKRNGGVYEPEMRLPIMLWYALATPLTFFWYGWSAQYKTHWIVPILGLAPLGVGMFGIYMAAQAYIIDAYPVYAASGLAAFAVLRSLTAAFLPLAGTDLFDHLGLGWGNSVLGFICLAMIPIPVLIGRFGTKIRKKYPLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WF42</accession>
    <name>A0ABR1WF42_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668269.1">
        <property type="nucleotide sequence ID" value="XM_066812927.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045987"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF2">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="35274" checksum="171C75B545786C95" modified="2025-10-08" version="1">MPGFLVSPHYVAETPNDSETNIVSITFGFCISLGFFTAAKAGQQSWDAYKRGKTFNEYIIIQFVLQIIINRIALLMVPASKARKVRWSVAAIVGAINISGFFIWIPARLQISPLYEEINIIWDRSEKGVFLVVDLALNIYFIYLVRSRLVANGLTKYNRLFHFNICMVVISVALDAVLIGATFLPSPVVYLPPIPSTDISHETVHRDECGQSHRQGSPRLISRWPPNGPRPPEKSQYYRTGAHDGATTHNKLTTFITANRTRHDVEAGLGTSDNGSVVENEGIRKTVETQVVHGKAEDDGVSETSSTTKVLRGPFLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMP7</accession>
    <name>A0ABR1WMP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein BOI2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669290.1">
        <property type="nucleotide sequence ID" value="XM_066810367.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043427"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13316">
        <property type="entry name" value="PH_Boi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037370">
        <property type="entry name" value="Pleckstrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12092:SF16">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12092">
        <property type="entry name" value="PLECKSTRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="373"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="539"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="617" mass="66338" checksum="DA9514C22B834066" modified="2025-10-08" version="1">MGSMDQGRRLSQSTPMGDPLSPMTPISPHLSQGSPTQTSHLRRPSAASVRDLHHSRRHSSTDYRLTGTTVTGSHAKLSSAGSLAQKELSTHRKQPSFDRNWTMGGASTTAASARPLSSTGLQDLNISADSVTDAPGGLDLDRGYFSGTEVDGRNKRNTLKKRGDSLAGHSQKGSYTEEQRVRSATALSRHSRFGSVDSSRDPPTAAQMYYGRSGSQSQRRMSTATTDSFRPVPPMKDGPAPTVTKLNNGEVEGSPPPNSSANRQALHSDWLAKPAKMSGFSGLRAISDAVTGTERAKLASPSDGSLRDSAKTTGSSTPSGGPSLDLESPGLAKSPLSAAANQNRKAAKQKTKQETSAYQRGLLKISPREAVKGADYSGWMKKKNSNLMTTWKPRLFVLKGRRLSYFYSEDDTEEKGLIDISFHRVLPADTDRLTGLHATITGAGNTPVAPADSDLASETLEKGDDAMFIFKLMPPRAGLSRAVNFTKPTVHYFACSNLKQGRLWMAALMKATIDRDDTKPMTSTYQQKTISLTKARQMRHRPPALMNLDERAEDPASLEGDDEKQNGLGISFGEVDSAVSGLEKLGLQRMESASARKPAFEEKGGNVSLPVSSPQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMR1</accession>
    <name>A0ABR1WMR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006096</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669334.1">
        <property type="nucleotide sequence ID" value="XM_066810411.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043471"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057688">
        <property type="entry name" value="DUF7928"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408:SF1">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25550">
        <property type="entry name" value="DUF7928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="311"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="722"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="754"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="794"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="850"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="880"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7928" evidence="4">
        <location>
            <begin position="88"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="524"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="906" mass="102210" checksum="5E3FA68D389B3EF8" modified="2025-10-08" version="1">MGIKSYFAPGQSKDDEKKGHAKKPSGTVDLKTLPPAAKHGAAPAPMSGLTTPKSPYGSRPGSVYSSHRASYFPQGDFRNQPDSLADVKADVMCSWLYQSQLERQYATGMLPGEGVVLKKGKNNFACCPPQLRDMPNGLLQSAMELNVRCAMTVNTRVIGVILNSRRATYDYIPISDNLQLQVLPSMRDLPRCQKHHFAAFIQDLQILVVWDDEPKKVLARADHLERQLMKMIWGTGEEEDVEPEEKDEKNGVEIGVSAVDLEAALVDEQRRIKLMNPFMVACTLALCLSCVGIGYRALALEISTDNNYIRLLVLIYVPISIFISFFFFGAIVGGLFQMFGPISQVDKNSLNYSGKAPNRLDRNFHNIPHITIQMPVYKEGLNAVIKPTVQSVKQAISTFEMQGGSANIFINDDGMQLISEEDAIARREFYEENNIGWVSRPKHNPKPEDGAKPFLRRGKFKKASNMNYAMMVSNRVEDRLVQVPRGSNWTQEDESTAYETCLAEVLAEDDNRTWAEGNIRIGDYILIIDSDTRVPADCLLDAVSEMEQSPEVAILQYTSGVMRVTSSFFEGGVTWFTNLIYSAITFVVANGDACPFVGHNAILRWSAIQDAASYFDEDGYEKFWSESHVSEDFDMSLRLQVAGYIMRFGAYTGDGFEEGVSLTVYDELARWEKYAYGCNELVFNPFKYWITRGPITPLFRKFMGSNIHFPKKLTICAYIGTYYAIGAAWIMTLVNYFLTGWFFGLYDKWYLDSFAIYISLVVVFSLFGNVSLAVLRYRLNQQGLISALFENFKWLPLMTIFLGGISLHVSQALLSHFFSIDMTWGATAKEVEEVNFVEEIPRLLKRFKGTFVFCILLTALIICAYHVFPYNWQIKTFASIFPVANLIICHFLLPVALNPALMVFNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNA1</accession>
    <name>A0ABR1WNA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006263</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669501.1">
        <property type="nucleotide sequence ID" value="XM_066810578.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043638"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF51">
        <property type="entry name" value="SERINE-ARGININE PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="7"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="131"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="204"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="282"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="354" mass="40308" checksum="DEC07EBDE8656092" modified="2025-10-08" version="1">MTEVSATRLYLGNLPKGDFAMCCITVGAFRFQCIANPGLFHCPVTKQDVESHFATHGTGEITEIKLMNGFGFIEYKDAMDARDVVPVRYPQDGSDFMGERLTVQFARGSRHREPGFGNHERTAPRPRRTAYRMQITGLPNDTSWQDLKDFARQSSLDVVYSETGREGNGRGFVEFENAADLRTAVEKLDNREFKGQRVTCVADIQAEVPGRDRGRSRSPRGRGPHNGGLPGDDYRRGPPRGGYGDRGYSPRRDDYRDGYRDRSPRGRGEYYDERRYGRSPPRRGPPMDDYPPPRGRYEDPYRRDYGPPPDPYVNGRPYDRPPRDFPPRDGPYPPREGAYPRDDYRRGGAGGGYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNS0</accession>
    <name>A0ABR1WNS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">lactoylglutathione lyase</fullName>
            <ecNumber evidence="4">4.4.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Aldoketomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Ketone-aldehyde mutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Methylglyoxalase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">S-D-lactoylglutathione methylglyoxal lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_006393</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glyoxalase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.5" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669631.1">
        <property type="nucleotide sequence ID" value="XM_066810708.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043768"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07233">
        <property type="entry name" value="GlxI_Zn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004361">
        <property type="entry name" value="Glyoxalase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00068">
        <property type="entry name" value="glyox_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374:SF30">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE GLYOXALASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="VOC" evidence="13">
        <location>
            <begin position="25"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="13">
        <location>
            <begin position="191"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8085122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="341" mass="38553" checksum="B13526D68FD0B48A" modified="2025-10-08" version="1" fragment="single">NREIAASTSRTFATMATTTDTKNYKFNHSMLRVKDPKASVKFYEFLGMSLIKKLEFPDNKFDLYFLAYDSPGALSSGNTTFDREGVVELTHNYGTENDDSYTVNNGNKEPHRGFGHICISVDHIQAACNRIEQAGYKFQKKLTDGRMKNIAFALDPDGYWVEVVSLKAGTKGADDPNEPTDPSATDPKTYRMNHTMIRVKDAEKSLKFYQETMGMNLLRTVEQESAGFNLYFLGYPGTKGVPEGGFTADYEGLLELTWNYGTEKDESFKYHDGNAQPQGFGHICVSVDHLDSACERLESMKVNWKKRLTDGRMKNVAFVLDPDGYWIEIVQNERFAGKPNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPT0</accession>
    <name>A0ABR1WPT0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670069.1">
        <property type="nucleotide sequence ID" value="XM_066811146.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044206"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="224" mass="25251" checksum="4B9793DD1AFDA342" modified="2025-10-08" version="1">MCFMIKRYAACVVFGHCIKEMPSYDRDTCKQARAEGAFGFCKEVKAKFVPEFTCPFCPTCSSMEDWLFSRAKASVASNRAAGRFEKPIFTEALLVQFRGMIDAPDHAPVATVATLTSRMETWAVASIEEQQAELAGSWVDRQIRLASDRVSMEGMTEQFASWVTAVYRLSLVEDAIFLAKCEQDEHRLQLLRMLAMDAEVLGCYKARLEYLGAWQLFLSFAGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ14</accession>
    <name>A0ABR1WQ14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670138.1">
        <property type="nucleotide sequence ID" value="XM_066811215.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044275"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF24">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="399" mass="43589" checksum="52BE675D4FC5E8AD" modified="2025-10-08" version="1">MPSSDLRSTTLQLSSQVAVRSSDQLEEDEELLSCSAVASSPPPSSGSFPARLPFRFETGFALFAKRAPRPFPPPFYSPPAGSFSDPLSTHHQSRDKRVFVGGELIRGWTNGDDAIYESDHFLCANDGVGAWSRRPRGHAGLWSRLILHFWVSAMEEDITKSRRSGEPYTPSPLSYLQAAYERTLEATSGPAECLGTTTACGAQLHYKNSDGPKPLLYVTNLGDSQVMVVRPSQRELVYKTTEQWHWFDCPRQLGTNSPDTPNDNAVVETVELKEGDVVLAMSDGVIDNLWSHEIVENVSASVERWESGQGGQAGGDRKHGANGGMDFVAEELMKAAKVIATDPFAESPFMEHAIDEGLASEGGKISVSWEKSKENVVLIRLGKLDDISVVAGLCQRNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRH5</accession>
    <name>A0ABR1WRH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669232.1">
        <property type="nucleotide sequence ID" value="XM_066810309.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043369"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="204" mass="22985" checksum="A6918E6069A967AC" modified="2025-10-08" version="1">MPSLDFAIPDKLKKECNVALNKHSRADELLGQGKMEEAENLLREAVEWSNQSLGAAHKMTVSYQEDLAILLAQVNKFDEAIKVNFAAWQARKEARDTSPSRHTAQLNLARDLTHKGKMEEAASHFERVYASQLSDAASFGKNHACTLRTGYELATCWFSLGDRKKDNHLRAKAKELHEDVLQRQLRGKGSRTVRYCSDPCSLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWH3</accession>
    <name>A0ABR1WWH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670414.1">
        <property type="nucleotide sequence ID" value="XM_066806796.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039856"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF188">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="220" mass="23787" checksum="72171F8983F03F42" modified="2025-10-08" version="1">MVLPCTNPTKSYWIEAADSPLRDLRSTKELPEAADVVIIGGGYSGATTAYWLDKYTRGHAKQPTMVILEARDICGGATGRNGKLVSRESLRGAVADHNSGGQLRPHAYSRYAVWSERFGADTAMELIRHEMAHLPAFAELAAEEGIAEEICLKLGETFDAAMTDEAWTRLKGALDAMRKDHGDDNEVVQACRVIADAAEAEDFSQMKGALAAIVHPAGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXW2</accession>
    <name>A0ABR1WXW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670857.1">
        <property type="nucleotide sequence ID" value="XM_066807239.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040299"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="290" mass="32107" checksum="5AF1C4F988E2D181" modified="2025-10-08" version="1">MGLRDMLKKKDRLSEGYSADATETVGRLAAPEFTFIRSDTHTEERIFPPAPEDEYQTAKDSSLAAAPAAKPRRSLDVFKSRSRGNSAASPNSNKADPFADASASPSPPLPSPQLPQQRQQQQQQQQQQNNSLRPKDTVGRRLSQRLHIGSSSSRRTSTSEFVPENLPTINLPPDAAEPEWEARATILAQQAEQARSRSGSVTPSPLAEKQNPYELPPLNIGAEYNGDRGSPPSRRRRRATSRGPPTSGRCRPSRSTPTFRRRYGYTRKGSWSSLRSSLAFWRIPMGLTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY04</accession>
    <name>A0ABR1WY04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sin3 binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670928.1">
        <property type="nucleotide sequence ID" value="XM_066807310.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040370"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018818">
        <property type="entry name" value="Stb3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28164">
        <property type="entry name" value="PROTEIN STB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28164:SF1">
        <property type="entry name" value="PROTEIN STB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10330">
        <property type="entry name" value="Stb3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="36163" checksum="F66E238195B09CBB" modified="2025-10-08" version="1">MASPASAAARDIPKTSIPRDNLTAVAAGRSVPTAHKHHQPLEPIDSDLDLHDGTETDSVGSPTFESAGAITPALLSKYHLPEIVLNHGPLAIRHIMGYLTTSVPGFAGIPPPKARRLVVAALEGRGHGHGHGVQGGGGVNGDVLFEKVGWGRWNARRRGQPCRSRMSPDRLSPEASGPTSYPAGGIPIHKAARRNDRSRLNVRATSIGNSAVFSHDDHDVNMMENEADKMSLDSMDSPASASCSEAGDDDMTMNDDPEDATDDEDWAAVGAAALRAGSYSSPADAHRDFSSRMNSTGAYRSFSGTGMLREPRLDNIDLAALAASPNTQEREAIQALLQLGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYE0</accession>
    <name>A0ABR1WYE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671075.1">
        <property type="nucleotide sequence ID" value="XM_066807457.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040517"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045712653" evidence="2">
        <location>
            <begin position="21"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="191" mass="20849" checksum="84EC4C07BBC1C6D3" modified="2025-10-08" version="1">MPSIKTVAVLLFWAFGLVASAASHIAKYNSDSLNGFLADSIQLTEQDIGDFSAIAFGDRAEASVTVSRQKQQRCRVFPGDDLWSPTEEWTRLNNSSTVPCSGPRPRVQSVTQNTPPTTRRSASSCSGTPGPPASGSTIRSRSWRSGRREHLPGHQRNADAGKELYTGWLPGVCGERHDGEARADRYQLCQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ95</accession>
    <name>A0ABR1WZ95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671376.1">
        <property type="nucleotide sequence ID" value="XM_066807758.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040818"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="115" mass="10929" checksum="3D648A67CBBBC8B1" modified="2025-10-08" version="1">MGGIPPLPPAEGIPPIMGGIPPFIGGAPPFVGGLLPSIGGMPPIIGGIPPFVGGLLPSAGGVPPIMGGIPPLPPAEGIPPIMGGIPPLPSVGGMPPIMGGIPPAPGEPVPGIWFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZR6</accession>
    <name>A0ABR1WZR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003576</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671509.1">
        <property type="nucleotide sequence ID" value="XM_066807891.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040951"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451">
        <property type="entry name" value="MARVEL DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF4">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="7">
        <location>
            <begin position="20"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="222"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="223"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="319" mass="34540" checksum="66091C8A4113589E" modified="2025-10-08" version="1" fragment="single">MDVRARKHGYEIIPTPVWVLVVRIFQIVLSILAVGMAGWWIHGLYLNELGFVIACCVFTWIVSLYNILSEKAAGCRAGYNTWATLSLDGLLIVFWLAAMGATASARASFKYSVTASCTSDGSAVDSGHCEVLRRRYTTTVGVASYGALDVLSGLAGVCALVMLLFVASFAYVCHFFRLSYTEANAVPDPEKQNNGGAAAVAPTAGAPAPGYSMNAGTEMHPVAQQGAPYGSPQQQPQYQYQAQHQQQQQQQQPLQQNPMMHQTSNAGYTQQTGYAQPTPEMGYSQPQTPAPYTQNNNHMPGTGMHSPGQVGQQQYPYNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X082</accession>
    <name>A0ABR1X082_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">28 kDa ribonucleoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671714.1">
        <property type="nucleotide sequence ID" value="XM_066808096.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041156"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040112">
        <property type="entry name" value="WetA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22934">
        <property type="entry name" value="PROTEIN ESC1/WETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22934:SF23">
        <property type="entry name" value="ZF-C3H1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="311"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="422"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="473" mass="51738" checksum="D0A6D3E9E9BD552B" modified="2025-10-08" version="1">MANEQQRPASQKLPAGLAGVLNPEENRDSAYFSCTDASSKHLDTSTASGVGINVLSPSSTSTGYHSTDKTPSPTTTNMLPQPLHSPVGSMSITSMVSPTTPGSASFARPHSLEVNPNGASLLLNGAPDSRRESVDSRINQGFGDMKLGNSPYASHNQHREPVNAPNIQRLPTERRPQSPEPHPKIRTAPAITGPATSNIARAAEPTKGQAWAFPEEEIQRMPSLTNLHDSRRSSIAESIASSQFTTESRLPPGQRRLDDGLGNDFQQRLSTASTDFPAVHHHSLQHKQLSDLQSEESSPHSGAQPYSRTPELRVSHKLAERKRRTEMKELFEQLRDLMPQERGSKASKWEILTKAIAEHQRQQDHLKQLTAHYQNSAQESELLRREVERLQHENGQLRAANGQGGPASASHAVSSQPPPADPYAQQAQYAASRPELPPLRTLATTMPNGPDSMTGVQYEGQRPNGFRPEPARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X190</accession>
    <name>A0ABR1X190_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydantoin utilization protein A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004156</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxoprolinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672089.1">
        <property type="nucleotide sequence ID" value="XM_066808471.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041531"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF23">
        <property type="entry name" value="HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="4">
        <location>
            <begin position="4"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="2">
        <location>
            <begin position="208"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="2">
        <location>
            <begin position="346"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase B/oxoprolinase" evidence="3">
        <location>
            <begin position="677"/>
            <end position="1193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1309" mass="143161" checksum="22C88A429889BD8C" modified="2025-10-08" version="1">MDYRLGVDVGGTFTDVCVITPEGETIRAKTASTPQDQSIGVKDGIEKVRKILKAKYNWEGEFSYIHHGSTVATNAILESKGVKAGLIVTAGFKEVLTNRRSQIPGGLGGWISFVPPEPVVPLERTVQCTGRISATGEVAIPLDEAALREDLADLKRQQPEAITISLLNSYVNDEHERAVVKIVREEFGPEIEIICSADVLPEAGEYERTVTAAANAVVKPIVKRYMDGLQKLLLPDSKTIRILKSDGALTSLSQAGELPVNLLMSGPAGGVQGVVDVISKQTPYRNLITLDMGGTSTDVALIVDGKPALRRETVVDKLTVRAPSVDHASWPRERRGQPRTGLLQERGTMPTVTDANLALGYLPDKLLGGDFQLDVQAAVTAVKSVADQMGISVEETASGILDLVNETMYGALRQVSVEQGYDPRDFALVAFGGAGPLHACAIGKLLGSWPVIVPQAPGVLCAQGDATTKLSEAKSVSYIKTLSSVSLDELKSILQNLEKHCTDTMTTALEGSSEKKISVTYDADIRYHGQALDITLQFGFSMEDLEFELVRLGVTATDASSPVEFAAMSSETDGLPSSVAETAVVHKKTITVEGRQVEATFYDRAQLNTAGLRLDGPCVVSEMDSNTLILPGFYGEIDQIGNILIRPVDESTLAKTKDFTKESAREEVAKSPLIPTLVGSALQAVRIEMDTLVLRCSMSPGIREQQDEFNVVTNEKGQMLVGQFGSFIGQFLRGWEKVGGTINEGDIFITNDPYSTEGAISHLNDVIILLPIYHKHEIVGWAANFGHLSDVGGKVPGSMCVSSSTIFEDGVQIPICKLYKRRVYNADIMDILCRNSRMPDWYRSDIAALVSSCKTAGARVCELVERFGLEIYQASCEELLKRNQMAVSKLIETQFGDEEAVFTDFIDDGGNGELGPFAIKCKMTKKDNKLKFDFDGTSAQSNTAINFYVSPTMFKMFVGYYLLAVFDPHCVVNEGLYDFIEVDFPEGSILRPVRPAALSCRTHLLGRIMDVIQALMGQHNKAYRAAAGFSDSPHFFYSGFKPDGSYFQLYSIAFGGVPARPLGDGPDMHCLFPSIKSVPNESTELAFPLLIEANESLADSGGAGFYRGGNAHRTRYRFLSRGEFSLHDDRWLTYPWGIDGGQPGQRSKKVLYRYSQSANPEAVYLHSKCDYMRVDPGDVLEHITWGGGGLGDPFTRPAEKVALEVHQKLVTHEGARKNYGVVVDPVTYEVLTAETESLRAELKAKHVEYPSIYNRGGTLEELRARFLEETGLPAPKAQWSEEPYGPHANLPYVKEWFKIRKAEGDFKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1N1</accession>
    <name>A0ABR1X1N1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyoxalase/fosfomycin resistance/dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672133.1">
        <property type="nucleotide sequence ID" value="XM_066808515.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041575"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39175">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39175:SF1">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase/fosfomycin resistance/dioxygenase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="151" mass="15796" checksum="397545D7EB4539EB" modified="2025-10-08" version="1">MAEEAATSPAAEPLITGIAHINLSIPPGTLTHAKSFYGETLGLTPRAVSAAQTETLAWFDAGAGQQVHVSTAKHAKDTTSATSSRHPCFAVASREALLALQNRIVAHHRRGGPDAPMAADPVGTSSGSKGAEYPTRFFARDFAGNRLEFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1U1</accession>
    <name>A0ABR1X1U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Catechol 1-2-dioxygenase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004328</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672261.1">
        <property type="nucleotide sequence ID" value="XM_066808643.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041703"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF7">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="9">
        <location>
            <begin position="45"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="8">
        <location>
            <begin position="176"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="337" mass="36484" checksum="1969494513EB7988" modified="2025-10-08" version="1">MLIPTKTVDEANGLEKKKSSSSSSKPQYDPEFTDLVIAATGPKANPRLAQIMPSLLRHLHDFAREVDLTVAEWTAGVDLINQAGQMSDNKRNETQLLCDILGLESLVDEITSKLLQQPGTTLTPSAVLGPFYRAAAPDLPYGGSILQLPSSSSSSTPAGTHGNGSAVPDWAQEAPARLAHINGRVLSAETGEPIPGATVDVWQAAPNGLYEQQDPSQPDMNLRGRFATRDADGAYSLYCLRPTPYPVPDDGPSGRLLQLLDRHPYRPAHVHFVVSAPGRRTLTTQLFDAEDPYVGNDSVFATKKELCVRFHAVQATTDKDEQGPKWEVAYDFTLGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X239</accession>
    <name>A0ABR1X239_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PWWP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672374.1">
        <property type="nucleotide sequence ID" value="XM_066808756.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041816"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00293">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="2">
        <location>
            <begin position="163"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="595"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="610" mass="65775" checksum="7B0ADF3D20691063" modified="2025-10-08" version="1">MADTEKSVAAQQPDKVETASESAAPAVDDVKMDDAPSASNEEAAEKTAASEAAAANDKANSDVDMNEAESVEEAPEAGEKTESGASATNDDSTKPAGESAEKKEDSAKDKEQKAEAVISEAAEGAAEGAAIEANGATPSSSKQAARRKSTGTPAAKKLNKKASKARMLHLDCVPGFPPWPVIIADESMLPQTMLSTRPVTAARPDGSYREDFADGGKRAADRTYPVMYLHTNEFSWTRNTDLAELDPETVKDLISVKMRKDLQQAHILAAEQNELEHYKQLLLDFQEAKLAEEEAKAAKAQAKKEKTEKKSSKKSEATAVDEDDDVEMADAGEDDEVPVKKPKSSKKRKAEEETATPQRSDSVKKPKIKLTTSSTPKAAANGAQSPKNGKESTTKASKPKSKAAKKDAEEKPAAPKEPELTPEERHVRKECLSIGKTNWGRHIKKEILFLRHRLQKGLLNRESEPKEDEMKSMSEFLTKLETFPDLEVSIIRATKINKVLKAILKLEGIPKEADFQFKPRSKSLLDKWTEILANDTGAAPAAGVNGNSAKESANGVKKEASAEAPKEETKEDGKDSDKEAETKAEVDAEDKPSTEETTAATEAAAVEPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X243</accession>
    <name>A0ABR1X243_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Translation machinery-associated protein 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004451</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 4">Interacts with the 40S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The SUI1 domain may be involved in RNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DENR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672384.1">
        <property type="nucleotide sequence ID" value="XM_066808766.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041826"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11607">
        <property type="entry name" value="DENR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050318">
        <property type="entry name" value="DENR/SUI1_TIF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046447">
        <property type="entry name" value="DENR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005873">
        <property type="entry name" value="DENR_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048517">
        <property type="entry name" value="DENR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01159">
        <property type="entry name" value="DRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789:SF0">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21023">
        <property type="entry name" value="DENR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="SUI1" evidence="6">
        <location>
            <begin position="100"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="193" mass="21217" checksum="277CBD0404BC1A41" modified="2025-10-08" version="1">MADTETADVPSEPQGRHVTYCGEIEQYCEYGGTAKKCQDWLQKAHPSMYEQIWSPEALEAATANLSVAAQERAAKDAKKKAAQAEKAEQKQADKMANSVITIKRVERNKRKFVTAVSGLEAFGLELKKVAKEFGKKFATGSSVTKLPSGGEEIVVQGDVSDEIEEFLLEKYKDIPEDNIELVDDKKKKSSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2F0</accession>
    <name>A0ABR1X2F0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytidine and deoxycytidylate deaminase zinc-binding region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672460.1">
        <property type="nucleotide sequence ID" value="XM_066808842.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041902"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF190">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="163" mass="17576" checksum="78510B0D03B461B5" modified="2025-10-08" version="1">MDDAKGLATAFEEAKISYDEGGIPIGAALIAADGTVLGRGHNMRMQLGNPILHGETSALQNAGRLPATSYKGATMYTTLSPCDMCTGACLLYNISRVVIGENKTFLGGDGYLKQRGVEVVVLDDEACRSLMEKFIEEKPDVWNEDIGVEERVYSKEGIKRPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2G5</accession>
    <name>A0ABR1X2G5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672475.1">
        <property type="nucleotide sequence ID" value="XM_066808857.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041917"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="30875" checksum="CA4CF8E25DE205EC" modified="2025-10-08" version="1">MQDQPLSGPVSEHPRGTARKKEEEKTEGNSNVPAWSPAILADNRFAAEAPPSNAPTIGTGTASNATSELPPTYEDVCLRPVGVSSEAAPLPRSERLFKTFEIVEELLIEHVLDELSEVLDNYSKLALVDNGIYNQLYTMCGCAGFLVADGSHIKLADRAIQSVPGMISEPFNEVVQMIRLERPTTIAQVAGIMANAVTKTVGQVMMKRMYRSYLPAQAWAHWSVSTVNRQAELVCSRLAEGKLPTAESEAAPTAAPTTAPTMAPTTVQKKRKSKIKRLFERILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2H7</accession>
    <name>A0ABR1X2H7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Post-GPI attachment to proteins factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004574</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the lipid remodeling steps of GPI-anchor maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PGAP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672507.1">
        <property type="nucleotide sequence ID" value="XM_066808889.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041949"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007217">
        <property type="entry name" value="Per1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148">
        <property type="entry name" value="PER1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148:SF0">
        <property type="entry name" value="POST-GPI ATTACHMENT TO PROTEINS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04080">
        <property type="entry name" value="Per1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 7" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045005182" description="Post-GPI attachment to proteins factor 3" evidence="7">
        <location>
            <begin position="29"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="38408" checksum="4B1500B436509086" modified="2025-10-08" version="1">MLARLHARIPRLIAALLVLCLLLNTAQASTGDQLPEFRECVKICKRENCDSEKPTPIPLHRRLLLWTCPQECDHTCQHIVTAKRVSRGEKVTQFHGKWPFVRVLGMQEPFSVLFSVGNFLAHQNGLAKLRAQIPASYHLRPYYEMFAYFGMAAWVFSTIFHIRDFAATEQMDYLAAGADVLYGMYYTPMLVFRVERPSPRRRSLLRLWTILCCSLYACHVLYLKMWRWDYGYNMTANVIVGLTQNSILTYWSYRQYREIRQLWTILPGLSVAWLMMVMSLELLDFPPLWGAIDAHSLWHLGTIFPAIVWYRFLVRDAQEDITSNAKLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3R7</accession>
    <name>A0ABR1X3R7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005011</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family. PalF/RIM8 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672944.1">
        <property type="nucleotide sequence ID" value="XM_066809326.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042386"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF161">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALF_RIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="323"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="553"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="602"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="666"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="621"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="678"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="722"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="735"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8090050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="837" mass="90389" checksum="63CFE713462DE911" modified="2025-10-08" version="1">MGATVDRTADLPLEDQPSKASSFFSRWTLPLRSRTRNLADFHVRPDEPHRQYSAGDHVTGSIVLTVIKPVRITHLTVALHGFVRVFKNAGAAAQLAPINPAHIPHDGNKNFRYYGNGQASLFQDEQVLCGEGRLAARKWEFKFDLIFPYKGLPSSIDFERGTISYMITATLTRPTTMAPTTSVERKISLIEKVDIGLLSPPRERNVTMQAMHKRAKRKRTANSAATGTNQRDSASTDTPEPASDMDSTRANENSNDGSATVDDHSRPLYDGLGLPRSPIQSDMQSEISGESAASNASNYFRGTDVSAGSVNGSKYSGPVAEVAGREITATVELLKGGCLPGDLLPVRIKIHHNRRIKSLHGIIVTFYRQGRVDYAPPASMFKELSEEDAKRLEREEYYPKSKTGLGGLSLSSAGSCSVFRKDLSQSVAPLIIDPTSLSANITTSVRVPEDVFPSIRGVPGGLISFKYYVEVVIDLGGRLAGQTQLGSQPPGRMGSVSVPAGPASPLVGSHENNISRLANWNGTIVDTDHIRREKGVIYVPIEVVVGSVDSNRTRGKAVARPTLTLESPSNQGFAPESDQPDYTWQNAPEDEYYDETGEYISPFEDTHSYFPSPHTQPTSYHDLHRQESHRRDSQEPQAPAYVAPPQMPDQTALTDKERVRQAEMRLLPSQPPLAGSESTAGPSRPSAPSAPGDHSSSTAGATGPSFLPPIDLGDSLDGPSAPTLTDLSLVASSHPTEDKQEMERRRLLEEASAPPDVPEEYTNGGPSAPVMDAAGPSGSHEHEPSAPNFDEGGSYGSHDILGNIAGPSNGHPLIGIIMGGNRCQSMNDDLMPGRCWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3S7</accession>
    <name>A0ABR1X3S7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Transcription initiation factor IIF subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_005029</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672962.1">
        <property type="nucleotide sequence ID" value="XM_066809344.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042404"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07980">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003196">
        <property type="entry name" value="TFIIF_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040450">
        <property type="entry name" value="TFIIF_beta_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040504">
        <property type="entry name" value="TFIIF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02270">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17683">
        <property type="entry name" value="TFIIF_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIF beta subunit N-terminal" evidence="9">
        <location>
            <begin position="51"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIF beta subunit HTH" evidence="8">
        <location>
            <begin position="275"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="137"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="350"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="359"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8090068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="383" mass="42836" checksum="C19E4338FBE78E34" modified="2025-10-08" version="1">MASSVKPEPGVKPEPEDAPVSPAVMSDDELYEDAGDLEFYNSTSPNDPSANLFLTHVPKYLYDQWAQLKEEEEVEVGRVRRWIETDKNGEKRERMAMLLDVQNPAHQTIPKEYNFEMRDNNLLNTFLFTEQDLPGFKSKSQGANSNIPHHLRNRQRDNANKDNSNNKPEGGRKRYQPYYRKAIPKKTVLAGRFKYELNCQPADTPETRHILAMRASDALKPKATTSMMSGMSGTRAMTKNILNAGAAPAGGRGPGFIQTAKSKEKARKAAPERAARLDKASLMDALTACFRKWRYWTMKAFKQQLNQPEAWLRENLEGVATLHKSGPFANHWELTDVYKSIVAISGDVAQSGAAPGDLGGDESDMDGDDDDENIQMEDVPAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X465</accession>
    <name>A0ABR1X465_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673084.1">
        <property type="nucleotide sequence ID" value="XM_066809466.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042526"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="476" mass="49707" checksum="FC17E82F57297135" modified="2025-10-08" version="1">MSERTKITLLTALPCIQASGTKYALVAVFVACSAFGGWATIGSLQKTGLGALIEAVLAGNRAAFPGGPEPFKRHWTGLAPVDGLLSGIVGFFSAIIDGSNAPDRSGKVEWDAYLFYVWFAAQFIAVWAMLLLESLRVGNRGRLVSYVGLVGMLFQVGTWTVVGPLYLALHLLTSPVASLNRGDGPRARRALFVLLWDMALLPAVVTLTNTLPAVIMSAPASGGVFLGGGLTASASAHYKAIAFWQFFPLWSVCLQAFLNPLCAFLFGSLLPVDSAGKPAPLGRGYLTGVSGVYQFALTVCVGVHAPLVAVSLAPAAARAWLAAHATSLYIPAAYAGLFETASFRGIFVPASPWTPPTIAVGAVNGGTIAYTGVAQAVAHFLRYDMLVGAVPFLLWAAYLHQTTAKQPLSPAALVRKVVFWSVVGGAYAPAVALLWGRDQVVLEEDEPLRVAAAVRAVAAGGGGGGTTTTTTTKKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4R2</accession>
    <name>A0ABR1X4R2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NUDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005310</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nudE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673243.1">
        <property type="nucleotide sequence ID" value="XM_066809625.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042685"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033494">
        <property type="entry name" value="NUDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006964">
        <property type="entry name" value="NUDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921:SF1">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04880">
        <property type="entry name" value="NUDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NUDE" evidence="8">
        <location>
            <begin position="131"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="199"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="356"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="456"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="471"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="532"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8090349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="569" mass="62697" checksum="9B99226586612BE4" modified="2025-10-08" version="1">MVEPPSSPPNADASPEESLAWYKSQYEQLANELADFRDSSHELEQELEKDLDAADKRERSLQEKAESLQFEADEWKEKCKNAKAEANAAQNALEKEITTLRETNRTMQHKLRDIEVANDDFERQARNTTSSLEDMESKFNQAIERTVMMEEEIKIGEQERETLRIEAQRLREELSDLKVEAEILQDKLKKAENRHLSTISTDISMPASPSYEHSPVSTASSPLINTPPDDVSLPPPTKDIPTIQDPPSPPRSDTSSTLPRPGSKTRLRTPSIVKSRIPSADRSVTPKPRALTSTGMRPSGTRAVTNTRTPAPARTTAPRSASHRIPTSNSLTHIRSLTAQMQRLEARVHNVRSKLPAPVLTPPRASPRSSVMSVVPSTVTVRSNRKRGAGSITSSLADETPSHSTGKHIPRLSTSGVSRLSFGPLPNRTSNYDPDSSIASISRPSSRASVSSAYARPERPASRTEIARPMSRSSMGRANTSLGLRSRSSMGNSLHGHSSSYSHIEFDEMDEADTARRTPSRRGTYSRYDVDGSASGIPTPSGIPGPRRESNVSRRTSHTQKLADLGETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X541</accession>
    <name>A0ABR1X541_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673363.1">
        <property type="nucleotide sequence ID" value="XM_066809745.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042805"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF8">
        <property type="entry name" value="CYTOCHROME P450 2E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="552"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8090469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="593" mass="66603" checksum="5CEC23D38AF6A1E0" modified="2025-10-08" version="1">MAAAPVFAIVVLLLYVVYLKKKEHDRNKIPPGARPLPGPKGLPLIGRIHDVPAEKTWLKFYEWSKVYGPIYQMEIFGSVHVWISSEAIAHDLLSRRALIYSDRPMIPNLPNNRTGGEYLALHGHTWKRQRKLAQHLMAQSANASLHNYPSKERDRFLYLLSKDASQYREYIEQFTARTVSRLSWGSPHPANLLRETTFGLLETISPSGALPHHLQKEHARHEIEAGLFRSSVKYVRDAVGNGTADPSFVRTFIDTLTKPGDEIKWGEEAEATYVVGQMAIAGALTIGSPIQSFLLAMLHFPEWQHKLQQEIDEVCHGRCPEWEDREKMPLLRAVVKEVIRWRPPVPTGIPHAVEKDDVYNGYFIPAGATIHAMEWGITRDETTYPDPETFNPARWLEPKYPTYKEPLTMHPNLAGFSQFGFGRRTCQGVPIVEMDLFLAMGGMAWAFRIQKKRKADGTEVPVHWNDFTPLLIAKPAPFEFDLVARSEATARVVQGMWESGKGDDDEEVERAAEFKRKISEDRRREAMAARVAAAAEEKEVVVDDDDVCSVGGSDTSGGSLLAPGVTPKTASSLSSTSSVTDFPQLRADADIWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7L6</accession>
    <name>A0ABR1X7L6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7726 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673396.1">
        <property type="nucleotide sequence ID" value="XM_066806100.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039160"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056143">
        <property type="entry name" value="DUF7726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42339">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42339:SF1">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24852">
        <property type="entry name" value="DUF7726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7726" evidence="2">
        <location>
            <begin position="142"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7726" evidence="2">
        <location>
            <begin position="282"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="395" mass="43165" checksum="D973CC2EDF75B409" modified="2025-10-08" version="1">MAETSRMQAKPLEGQQWAAAELRQREERRYFEERRTGREPWEIPADVFRDIALDEIGPSIGRPGGDRYALMRTAGNESSRYPANRSVAFGVLKEANAAAVERGKTVHRAATAGRKRKSGPHSLQDDIDNYKQSLAHIDTTTMHVDLDCDQVRDKINKVLESGIFKKTEFCDAIVVSNAAVNAGPDDGSKSDTFTKAWDWFKREIAGLRLPNANKRRQTEAARAAAAATALPANAGATTGPSTAATRNAPVSPVSGSGGTSSSMHSVPDISGIHLPGEDTDEVPVYDTCDMVREKIDAHLLAHKGLTQAQFCRDIYAHGLKPPTRCKGIQPKQLSDFRHKQGSNAGATSSVFYAAYVYFEKIRLAQGAPKSAHRLEMERRWGSEGSTGIAMTGRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X892</accession>
    <name>A0ABR1X892_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673654.1">
        <property type="nucleotide sequence ID" value="XM_066806358.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039418"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="334"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="416" mass="46277" checksum="FE95977E18F248BB" modified="2025-10-08" version="1">MTLPMKTDQTPFMRGDRLDMLQALDCSSYYELSLALSQNASALSLHTNDLDGMSRARLKIEGDRANGRPLAILLHCIPRALMRSIIAGTVAYDSINQSTPSPAVYSADGAGTYVAGVAIQGRNGKFLNYHELLGLAAAMEDYCKSYARQKSRWIADDRALRAVELFAQSLRDRLAAIDHDGLSKTIFHIQSPLMVGYGNSLRDCMPCNTGSDGSNLRFTAYTWGLMLCCIQARLQLTPQAVVQPVVHVLQNGDLAVSEVLVTALASSYCFQDGVNVVGAGATSGRARHQTLMNSKKYMFCEMPYWEENYEATSKELEKRSNYVSDVWLCSDFYSAALKREIEDLETQIQRIQIKGSLWEELMKRAAKREEELRKEGEALDRAIKSRQAMLKIFDYLLGNKTLAELSGQADADDDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8G8</accession>
    <name>A0ABR1X8G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673710.1">
        <property type="nucleotide sequence ID" value="XM_066806414.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039474"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="7556" checksum="0C2AD79BCD4E9DBE" modified="2025-10-08" version="1">MEVIASIAGIAQAGTALSKAIYTLVYATRNAPKEVYDIARAVGDLSIILSELRRVLRDGKNIVRETIAAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8X6</accession>
    <name>A0ABR1X8X6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673846.1">
        <property type="nucleotide sequence ID" value="XM_066806550.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039610"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="590" mass="64285" checksum="9E8EE0D1981D1C0E" modified="2025-10-08" version="1">MRKSIAQYEEASPLYGFLKYRRRNVIVKYQPEGCSRLVQVHFNAVCDNFQPFNTTFELTNAKDLKDTKLSAACSLHTATGSTSSSTSSLRRRRLMEITEEEEEEERERKRQSIVHDEEENEDGSETTPHSPPLSTPEPPVVLDRQQITDPQGPDFASIPDPATFSGAIAQPASPSKSEFDIEPPRRQSSQLTRPELHTYSSYPYGKPKVKLAPRPSMDANLRPHTSGNYRPIAALPAGFKLAKAVKKNKAEHKMEEEEMNQKEQGNSTTNATSAAAHEDHQNPGAANSTNTTLVLPARPATSSGASLKGSSALADKNKMTPEKARLMKAMKLREKKKKLSLLPTEVVPEPEPPKTESTAMDVQPPEDRIDGDDDQSHDKLDVEPATTGTEQPELPTLPMHSEANTEDTSTASHPPSPTVGSSEVGVSTKASSLSESTDETVQYAAKDTGIDADDGPPGPENQDIPNDEVHYMENEPREAEPLASATIPNNNETADSPVVQHEAADEKPDVSEASEEPLAEGSPKPSENERQAVNVTAASAASPKEATAATDESKIEVQIPQSRSQEVAPLNQDEPSPKSPLWRTTFQVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X984</accession>
    <name>A0ABR1X984_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673951.1">
        <property type="nucleotide sequence ID" value="XM_066806655.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039715"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13278">
        <property type="entry name" value="PH_Bud4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012966">
        <property type="entry name" value="AHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052007">
        <property type="entry name" value="Bud4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08174">
        <property type="entry name" value="Anillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="1338"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="135"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="229"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="504"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="959"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1162"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="162"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="392"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="562"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="578"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="634"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="676"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="693"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="728"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="741"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="782"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="805"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="839"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="959"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="989"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1008"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1019"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1040"/>
            <end position="1052"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8091979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1505" mass="167906" checksum="A740473463E01949" modified="2025-10-08" version="1">MNPLHQITQPLRISKGSGTPSTTPNKSGLPRPLSEISVGEKRRNSPSWNQTTKTTLVLLASSGRAAIPKRTIFMAEAHRPPTRRSSIERLQKASRVKNSTMFAREQKQEYDPTRIPTIERPLAKVSNSAYVSNPAGGFRSSHGRSDSQSSVPLYSPGRSIVSPMTINSPTPLSPRSPSKDQVSPMKSSLSNHRFKSSHDSQPADYFGESALEDNDLPWGKSLHRNMKSVTFDNGPPQINEYEMATPDLSSIGTNSREGSYDSEEEDDEDAYGLYRDEGDLHEDSFDATLEDTDKTPVVGPEEWRGDSCEERYENSPLPEGAPSPADTARPQHGHGRTDSTASSGEHRPLPPLPGMGHVRTQSNSSSNGLSATAERMLGSPRRDLPTPPPAATSKSEMQNIGNTKMSLEERLKLMMLSEDTSPKAISTDPIKSFAEQQRERRMRRAGPRDRVESPTPDDNEEAVESEAGDEAGEEDDTIGDISGLDMDYQLPSISRQSILQRVNGNKAFERDSDFHFNSSPAPSSPERQLPFNPDVPIDSIEESVLEDVAEDSASSVLLNGTEDEKSDVYDLYQRSEDDQSEVDDTLKDDDSESHYSDEAQRHHQEDDEDSVMTPRAGSSGEKLSPAADSGIDSGITNFSATLPQVNGNKQESEFTRSLQSFMLPKPKAADAFTYTESRKPKEDIDDLTHAEDDKQDQDQDDDGFSYTESHDTDDDDASSYTESHVTEDAEDEAEDETATEVDAKADSQRRATTPEKKSLPKIDYDGSGWGSKADYDGSGWGEPEEEEEIEEPGTPESVIHHPVSEDEYTEDEEEEEDDEEMPDEPLESPEVPERVATIKSASGSKLKTRPSATPSDLAAMREARRHVSREVPPIIPPIPSRHKSHLSTDVGEEKAGNEEGNGEEEDFIDRHPSFKKRSLTLDLDLGLSLDQDFERVIEQQKVQLQQNFFQHEFLAASNSPTRQASRTQNMVVATDRTPGRTPGRKLSNEEMQLNTNITNRKQRGYLMRQNTKVVTASDKQSEEAREATRSADNSPATTAKYEEENDPQHERPSPPMPGQESNATTALNNVPEEDAAHPELATEECGERGRLFVKVMGVKDLDLPLPRNERTWFSLTLDNGVHCVTTAWLELARNAPIGQEFELVVPNDLEFQLTLNVKLEKPPEPQRLPASPTKMAKPKTSTFSRVFASPKKRKEMEARMRAEEEAFVQAQRDAATRQRKVAPTAWDLMSPLAADDGSFARSYVCLKEHETHCYGRPYMVEIAAFNEWAVEEAGFASSVKSKRGGPSNSVVRRAPYKIGKLEVQLLFVPRAKGSTDEDMPKSMNSAIRELKASEERLSRNWEGHLSQQGGDCPYWRRRYFKLVGTKLTAYHEATRQPRATINLSNAKRIIDDRRQLTQPDTTGKGGKRRRSAFAEEEEGYMFVEEGFRVRFNNGEVIDFYADTAEDKDGWMKVLGDVVGREGVEDDTMHGGNRRKWCELVLKREEALRKKAEGRRTHSKSKSMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9D4</accession>
    <name>A0ABR1X9D4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002401</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674012.1">
        <property type="nucleotide sequence ID" value="XM_066806716.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039776"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="39"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8092040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="629" mass="71507" checksum="0FB9F5B068790F35" modified="2025-10-08" version="1">MDKSHLAPNAQTGRLRSNSQDSTFQPIMNPNTETRRAPRKLVLCFDGTGNKFHGDDSDSNILKIFSSLTHTSTAARIRSWYLKMKDSAVGSSFDQHVVGGYRFLMRFYSPGDEIYFFGFSRGAYVARFLAEMLDYVGLLSHGNEEMVVFAWKAFSRWQARRTDNSEEGVAQKREMYRFMKGFRETFSRPVKRIRFLGLFDTVNSVPRFEAAWMQRSKFPYTAKTNAKVIRHCVSIDERRAKFRQDLIYQGAAENEKKHKRHHYRPQFNVSRGKNASTNGAAADTPNERYRTRRLAVSQPSQQQPRNSVAEERGRKDTLKLPDTERTYRPHSRSRSRTSRGSAEAPSTSHVDFEYESDSEDDCQDIDEIWFAGGHGDVGGGWEYIPGSKSASHVPLAYMIREAQKAGLHFDPEKLVELDCTASLDNEYLNSPPQSSGGQTDGGNGRVPDIHIDAASPSPESAEEEKNMDATDWSHFSGSHVDNGHEKKNQYHLHPFHEMMHQAHVSLIHDSLEFGSGLSYTQVMSWKIMEYMPFRRMDLQSDGSWKPIRWPLPCGEVRDIPHTARVHGSVIRRMKLDPKYRPGNLIVGGGGRGMRRAPESYGMGEWECVAEEGDPVGEVWVKKTPAPSEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBF4</accession>
    <name>A0ABR1XBF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674798.1">
        <property type="nucleotide sequence ID" value="XM_066805025.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038085"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046738275" evidence="1">
        <location>
            <begin position="19"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="210" mass="21803" checksum="0B66B3EF76FFA420" modified="2025-10-08" version="1">MQFFTTALAALSMSSVFAAPVVEQRQAQNAISTVFSTVADVKVTLGDELSTVTKLVGDLKSTVVDDVVQKKTVATVQRTLSNVETELHGVLGLVLGTVTNTVVPLVGEELDNVPVLLKDVKTIVEKVKDTVTGVVGDVTDDVLVTLKPELKLVLSLVNTLVTPVVQLATGLVGEVTDGVVPEVTSLVGDVEHLAGGLLSPVTGGLLGKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBN6</accession>
    <name>A0ABR1XBN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674800.1">
        <property type="nucleotide sequence ID" value="XM_066805027.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038087"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="40831" checksum="22FF5A77F784959A" modified="2025-10-08" version="1">MDPGVAERQRRHFKNKHAPLLRKTLLDDLLKAKVQADKVGQGSGSSNDVADNHGLTPKFRATVNIGANTYLLAMSRSDLRARCPTWNELLIKKKKKKTDGVDHSHMRFKEEDLKALEIVLGLVHGIPPDLSDLPLGGVRSLTIVSTKLEVTTLVNVWARDYLSDLKTEIESGKNANAPGVDMLGWPCALRLSAEFWHRDMFILASRDFIRRGKLLKSEGNPWLFGSIEWGGRTLELSQQGLFADTIMANLSKREGIILKIWTFLHEEQVELSWWKTSEAHQMAARKLRKCPCAFHDAQVLSAQCRGGVTDFTYTNGSVDDIIAYIEDIGVQTYDTADKTRDILGEVAKEVDGMVANRLDEMTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBR1</accession>
    <name>A0ABR1XBR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000792</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674880.1">
        <property type="nucleotide sequence ID" value="XM_066805107.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038167"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNase III" evidence="4">
        <location>
            <begin position="90"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="312"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="340" mass="36906" checksum="830A2F226D75F2D4" modified="2025-10-08" version="1">MSKRQFSEFSTNVNANDAISAIIHNAESLLKAACALKADLASGKQNSSSTEAISNISRDLLPAVTYFAGSSSSSPSNKAPKLDLDGPSTFTHSGMVSKPGDMSYERLEWVGDAYLEMFATNLIYQTFPNLPAGRCSQYPGQTYHISPEFDFGSNINGQGAKAKTHRKVLGDIFEAYVAAVILGDPQSGLARASSWMKALWSKEFAKEIKTEYNARQRSQQAGADAASCDTPSTSASAASQDAHPKTRLTQRIGTKGVRIYYLDEYQSVDKKSKQPKFTVGAYVDAWGESKVQLGTGTALSKTEAGAKAAQNALDNKKLMKKYEQKKKELEDTMKAQLQCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBV5</accession>
    <name>A0ABR1XBV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000865</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674953.1">
        <property type="nucleotide sequence ID" value="XM_066805180.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038240"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF69">
        <property type="entry name" value="PEROXISOMAL LONG-CHAIN FATTY ACID IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="455"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="700" mass="79307" checksum="91C5D94E40100DAB" modified="2025-10-08" version="1">MAVQSKLVLPERSIKSVVAQLTGLYVKNRTRISRAVYLTLLVALVNRAASAREAAKRRSGTTSSEGADVTAKKKVELNREFFRSLLRLMKIVIPGWHSKETRLLFSHSFFLVIRTLISVKVAEMDGAIVKALVKGNGREFLMRIMWWMLIAMPATFTNSMLSYHQAELSLKYRTRLTQHIHDKYLSQLTFYGISALDDRIKNPDQLIAVDVAKFSNSLAELYSNLAKPLLDMTIYTWSLSKSVGGEGVVFMSLLVQLSANVMRALTPPFGKYVADEARLEGEFRFQHSRLIDHSEEVALYHGHEAEKDTLDKGYFTLIKHVNYILRRRFYHGVMEDFVIKYFWGALGLLLCSVPVFFKLPGQLAGGVVSMGDRTETFVTNRRMLLSASDAFGRIMFSYREIMELAGYTSRVASLLEVMDDLQAGHFEKKLVSSSGTAEHEAVLQGRGKVVESKNIQFIDVPIISPNGDVLVKALSFTLRQGDHLLVVGPNGCGKSSLFRILGGLWPVYGGTVHKPPFSDIFYIPQRPYLSRGSLRQQITYPDSLRTVRSRGVTDAQLLDILKILNLEHLVDLYPEGWDAEAEWRDVLSGGLQQRVAMARLFYHKPRYAILDECTSSVTLETEKIMYDNAKALGITLMTVSHRRSLWKYHSRILQFDGQGNYVFTKLDADKRLKLEDEKEDLDVLLRQVPEIERRIGELTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCK1</accession>
    <name>A0ABR1XCK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000988</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675076.1">
        <property type="nucleotide sequence ID" value="XM_066805303.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038363"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="84"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="336"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="377"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="501"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="541"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="195"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="696"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="837"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="696"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="847"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="918"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="952"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1051" mass="114195" checksum="05B575D8687AA79C" modified="2025-10-08" version="1">MEPFPTAPEPDEGYSEHPLSADNNALALPRGLQSPTEFSSWLAPRLSTLSVAHKTQLAMAILGDLPTTVIADIVLKQLNPRLYIDFVDYLPTEICLKIFGYLDPISLIHVARSCRGWYELAADRKLWEKLFYLEGWRALPREIAAAEERMNAGLSNTGVIHPQRLRSSEYGHAHKKRAISDPTPQDIIQSDAMDIDNDGRMDADDTEMAGTSLFGGPAVNGSTSSSKSTASVAQHLGHLMMESPSPMPESAPESRADIKGKGKARADDDGQQQAPAPVPSLSLPSLPTSSLWTYDARDMRYKINWQWLYAMRRRLEYNWETGKFTNFQFPHPNHPEEGHGECVYSLQFNSEYLVSGSRDQTIRIWNMQTRRLVRQPLRGHVGSVLCLQFESDPEDDLIVSGSSDSDVILWKFSTGQPIQRLRKAHTESVLNVKFDKRILVTCSKDKTIKIFNRTPLRAGDLGYGNVNGVNPVPINIRHPDHEDFALSQLPIKPPYTQIGCLEGHGAAVNAVQICGNEIVSASGDRHIKVWDWPHQTCRRTFLGHNKGIACVQYDGRRIVSGSSDNEVKVFDRETGLEVASLRAHTNLVRTVQAGFADLPYSVEEDRQTAREIDQEYFRAVESGRLGDTHNVRGKSLNAGSRRPEDITAYGAKLPPGGGGGPYGRIVSGSYDQTIIIWRRDKEGVWRSAHTLRQEDAAAAALRQSAATRAPSPSSSGGPAPMVMRATPARPLPPASAPPTIQQAPNATHVEHPIHATVTPQTNTSYTRMIDLTVPQGPAALQSTLLQFPTMLTYHSHLQTAIDREPNPANRSQLRQVVATALVRAQVAQNRIREAAADQPIPAPTHHQPAQASSSSSARSTTPTAQAPGGSGPPSATSSSTAVPSPTTQQGSSSRLSAMLQGRSRSRNQASGSRTAMPVSGTTVPSSSTTTATSSSTSAGPPTVASGAPQHVTALQQAQAQAQAQQPATAETSSAQPVMTIAAAMTAAAPAPVPAQHHPHIAPADQNPRVFKLQFDARRIICCSQTSTIVGWDFYNGDPELEEACRFFGPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDJ0</accession>
    <name>A0ABR1XDJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675469.1">
        <property type="nucleotide sequence ID" value="XM_066805696.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038756"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="155" mass="16497" checksum="24825A49EFE82DEE" modified="2025-10-08" version="1">MSDNFDYLDFNTLLNQAAYLGTHATEPDPGQASLTDSPFLGDDSLLDYNQSFGWAANAGFNQFTAPGSLYEDFDIDNTAFDTDGFLLPNNTQPFVTGTELGALSVPPLPANSAGQGFATGDILDTTTAPVIGQQRARDEFALWQPDAGCDATADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDV1</accession>
    <name>A0ABR1XDV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675639.1">
        <property type="nucleotide sequence ID" value="XM_066805866.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038926"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047285727" evidence="3">
        <location>
            <begin position="26"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="537" mass="56759" checksum="A40BFCFB1F95F2B6" modified="2025-10-08" version="1">MGRFWGCTSCIGLLAVMMLTREAAANHDARYKIHRIEKEYATILATLGTRSVQQALEVTAVLVITRAPRRIAMQQPQGHRKDVDRPAIIIAAPKCLVGYYFTNSHEIAANIGLGQCCPNNYICGKDQQCTPTAGQAATQTCPPNYYHCPSSLQGGCCSNGMGCGTDVCYSTDPSTAVVSTARVTTDSNGRTITSQLLYTTTMLPTPASITSGQPGAVPKLMASTISKLPAIQTVQSSSSSTGLSSAALGGIIAGVVVLLIVVVVAAFIVIRRLRRTEKAVEVSKRGSSNGQQTSSSHKSHKEGFGSTTVTEVDIDPLSQETPSLRPSRYRAGSDSSYNGRYSSPARSPPLSDGRSTPPAWPGNYKPVFNGGNDGTRHPSIESMGGQYAAQRVSYESQSTYRPGRWSNASEVSGSADGAHGQSELDAIETAGRRRSSATTRPTVGSRRQSGDSAYRGRSESAAAGTLAPLEAVNEAAELHGYYGPQDKQVGQTAARPTSTGGLQEGVELLSGNKGLSHEGWIAAHHSYTSIVFLPHTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE14</accession>
    <name>A0ABR1XE14_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short chain dehydrogenase reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675714.1">
        <property type="nucleotide sequence ID" value="XM_066805941.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039001"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="27884" checksum="CA85A85C7D8A3C10" modified="2025-10-08" version="1">MANLLRGTALITGAASGIGHHTALSFAKYGKSKLALADMNPSALTKSAKAIRAQYPSLQIVELTMDVRQTDEVKAGFAATVAQFGRLDVAVNNAGIRGPAARTDETDEAEWAETIDIDLAGVWRCQREALRVMVGQEDLGPREGRGRIINTASMLGLSAPPRGLVHTPYTAAKHGVMGLTKADAVIYGEQGIRINAICPGWTETPLIRDPKLPLLTREIERGAIPRIAHVDEVADAMVFLASPLSSFMQGASLLVDGGFTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQG7</accession>
    <name>A0ABR1UQG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660585.1">
        <property type="nucleotide sequence ID" value="XM_066819700.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052760"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045830473" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="31598" checksum="6F8D65C452545828" modified="2025-10-08" version="1">MKPSTAWALLGLLRAMPAAAAAEGDDCPEGQRVTLSPGYTVEYRRGRYREGDVHQGINSHAECMKLCQVSARPVCSFHEPTKKCIVGTQCGKDIVREGVCYMEERQACLTEKLACQSEKQACTKREGDLQAEHAACQAQKGTLQAEGSGCLARESVLKSSNSACLAQKETLQAQTNTCNTQRTAAQNANTACQTSLQQCNARAGAAASSLHATRPPPAECGRKGWGQGWYNVLSGMKMGDCRKRCQAEAQCVAYSDDVFSDWGNCYLYNKQLSTLNVTPYAYWGTYAKNCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQT3</accession>
    <name>A0ABR1UQT3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660477.1">
        <property type="nucleotide sequence ID" value="XM_066819592.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052652"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="432" mass="50055" checksum="13F73F6056E9923E" modified="2025-10-08" version="1">MDPITKNITGIQDTVNTLGRDVEKLRSDVHLAQLSAPLSSIPSSPPTPPVDQQARTTPSELQTRLRRYQYILDRTRSLPKNQFLDLVTEEMQRIWQKTDPRSAKHPKLPRSMKTDRLRTQAALAIKEVWVKHGMWHPSFEGLIYKRYLNVGVWRHEEPLPLVDEDGVDLKKWPNTYAKLCHHRDNSRPYHQFRYQVEKARDRLLEQWRQSITNSNGGTGNEEYPTVTIPSSRLPPPQIDTQAYQEVRKAWTKRRIWDKEWEVLPGQSWRHERPLEDFLTPQEAKWLSEIRTTCVEPGFDGPHRLVHRVESEKEFLEIFERRRGGVFQVRDGVVDPRRGLKRGRGDFLSELMAAHLSGSSDLGDDEDLSDDYISDDNGDGKPPEKKMRATEVPDETVELPTKGGAQGSVEQNNTERRRRAYKSPFVVDDDESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUX1</accession>
    <name>A0ABR1UUX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661322.1">
        <property type="nucleotide sequence ID" value="XM_066819134.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052194"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="10"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="198"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="270"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="284"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="492" mass="54903" checksum="DB60836DA4E62FC8" modified="2025-10-08" version="1">MFLWRTRKYADMKIVCDGKYWLVHRNILASRCAWFNDRIWKLRKKEGYYELVLEDHHHLLVRAFLYFIYNGVIDHEHLRDRMKPDNVVLAKLHRMGIDFDLPELRDALVTMLTKALNGRIEYIAENPTEKIKVTGILGGVKFAYSRAEHQQAELRAAYLNFFSRCLKQIGPNSHFYEKIRSIPAFSADLFQVMGRKNWGDESDEDEDGESESDTKARRQSRKKSGKEYGKKHDKKTASMAEFTIEDADLTRLRGKVIIVTGTCTPRLAHRRFIRNRASNSRAPPRPRRRRGQRRPVPPPAPQVIYPSAGSDAAAFFTGPSKSTAASTTSSPMRRASRSAATMLTTMALGAGGELQEPCHTVLDVHLKGTINTTTLAIQYMRTQDPQGGSIVLNSSTTGLHGAGGVDHVISKYGILGFARGVESNLDTAALSIRVNVLMPGPADSQVVEVIAADAARDVAQLMADSTKDGHVVYAGEGRCSKIEEAVLLPAHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV36</accession>
    <name>A0ABR1UV36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661382.1">
        <property type="nucleotide sequence ID" value="XM_066819194.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052254"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="127" mass="13650" checksum="6766C18E5CFF9FCF" modified="2025-10-08" version="1">MSLSPPNISASCPPIDKMMMPDAQNIAGLPLNITTYLTPAEDSLYENMVSCCSPNPVGLADGCYFWCEHPASQEAFQTWSGCLTKNKTRGFILGMHEAGAARLETGAPKKMAMVLLAGLIGSAFTWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVL5</accession>
    <name>A0ABR1UVL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_015034</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661536.1">
        <property type="nucleotide sequence ID" value="XM_066819348.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052408"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="121"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="573" mass="62271" checksum="A89CC4991B8192A3" modified="2025-10-08" version="1">MQFSRYKIAVAVAAAAAPAFVTSTRAPARSVPQCHVLPGDPGWPSTPAWDALNATVGGRLIKTIPLAALCHDPQYDEVACQELRDKWTLATTHYESPSSVLTSYWGNASCDPWTNEQSSCMLGNYVSYAVDVGSAEDVVATIKFARERNIRFLVRNTGHDFFGRSTGAGAIAAWTHHLKDITKLDWRDETYQGPALKLGAGVQGIDALAAAKDEGLVVVAGYCNSVGLAGGWTQGTGHSPLSTQFGLGADQTLEFDVVAANGEIMKASRKENSDLYWALSGGGPGTYGVVTSVTIRAYEDLPVGGMGILLDPTNINTDKYWTALRKLYSILPTVTDNGMHITVAYNSTSFIISGVTAYNQTSSAVTETMSPFLGVLDALQIPYQSWLTDSPTYLEHASHYGDVREATLRWQAGDRLIPRRVLADPDSEAFDDLLAVLRGLYDGGVEAGVTVMAPRDRVGADNAVHPAWREAAVLFGMLHPWDGAPSAWDEMRAMQRRLTGMLPALERVTPGSAAYVNEGDPFQENWKEAFFGPNYDELLTIKDKYDPEGVFYARKTVGSDRWDVAEDGRMCRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWE2</accession>
    <name>A0ABR1UWE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase C14 caspase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015089</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661591.1">
        <property type="nucleotide sequence ID" value="XM_066819403.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052463"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="2">
        <location>
            <begin position="228"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="735" mass="83122" checksum="345A9F4628849AA0" modified="2025-10-08" version="1">MGDRDDTWSIRADGEYLPGENNIWLQEMSRALPGAEIMAYGYAIHHKTRLSGLLDPDQLESQVRALSQTLGAHLSCHHTAADTQVEVDDDQEVTIDQKFRRPILVLAHGYGGLIYEQALDLANPQNGKQCLTLFFDFFKDRYQLAFLFGTPHFPAGLGEWAIISVTKHRMTPEWAALPAFIPMVIRADHRGMTKPKPENPDLKRVFRMVEAWTSDMKAIMPSITRGIRRFALLVGADHYDNGHPGQQRISENGTPFRLRDLHGCSNDIDLIDVVLEKHFDIHEKVILVSSPGKDQYKTQPTFRNIKQQFHKLSQRVCEGDVFYFHFSGLGALLTPADAQSEHSREEEHIFPMDYCLGEPAIRVNQLLACLEELGSRGVQVFAFLDASFGTCIPFGQSSVRTNCNRAPHFDSAPCNGEPDHETFQKEWAHQDRRDTPGDGVESPGVTYLSSCAAEGGVAFEVPQSISGGSERMYGLCTFLFYEQLHNVWCNGEVASYQALCGTAFGKVKHMTRAEARTQRPRLLGQGDKLFLGDREHPLERLVLSLKIVDQTATMSAGSLHGIKAGMVFISRQVVPFITFTVEDVKAFTSMVRINKLSSNPSQDGAPWAKHTLYLRYMPEELTENPETFSINPFDIHWPEQYSHLKVTHYQRVADDYLEVFVDADNRVIKHETGLLKQLKQRYLSEFRVSPISMRDWESLRPRNGVLMKYNNVGRIGEIERDGLDVFFEAGKAISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UX49</accession>
    <name>A0ABR1UX49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661215.1">
        <property type="nucleotide sequence ID" value="XM_066819027.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052087"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="189" mass="21276" checksum="6FE92F68439EF2ED" modified="2025-10-08" version="1">MWIDTCRISKANSVEETESIDSMFKWYRDAKTCVTYLYDVKRGPEPLLEEDETMAADSNGLPNVFRRIDHPGQPSAWSFCGWTLQELIAPHDMQFYNTDWASLGTRAERAGAIVAVTGIAVEYLTGQKPMHSACIAVKMSWMANRATTLEGDIAYSIPGTFDQYLVREPSSYFHSFNIQGKVLSENSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXV3</accession>
    <name>A0ABR1UXV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661484.1">
        <property type="nucleotide sequence ID" value="XM_066819296.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052356"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="142" mass="16320" checksum="FD86FF51296A08DC" modified="2025-10-08" version="1">MMQVLEAYVPHYELSLLDRMLLIWLFIGSAFVVVLQVSQSWMEPRPRWTVLDERSKPYWYTYYVYLAFLLVQISYRPLRHKMDSMQPLLSIGGFEVAAAALDGAWIGLLSLEALMIVFVLALQVTQLFGKAASPAAYKLKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UY97</accession>
    <name>A0ABR1UY97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_015118</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661620.1">
        <property type="nucleotide sequence ID" value="XM_066819432.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052492"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="54"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="336"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8063021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="404" mass="44661" checksum="BF80ED0702A285C6" modified="2025-10-08" version="1">MSSDSNNSTAGGSDNDPLAGLIPPPTEINDTHKVYSVAAACIALCIVACLTVSARLVLRVRKRDIGLDDIAIVPATLLYIGWTGLAAYVNLHAGVGKPLWEVTMTEFTIWFKASLPIAILYDTFSSLMTGIVAAAWLYPIMSASIRVSTLFFYRRIFAKTSDRLKNIIWALLALQAVYVVVFSIVPGFLCRPFYYAWRPLERQLHCSDLYYYNYQVALYAVSMFFDLVLLVLPIGPVWRLQMPIARRIGTVVLFALGAAACVAAAYKLGVFVDQQNHYIPTDMTWLQYLVSRFVPGQFNLYGTTFWIPSQVEPTVALVGTSMPALKQWFRHASERLGSRDTKNTSAHSGSGSNHSKHLPRVSAGARRSDTSLIGSANEQQGISLDAMGHSHAGQERAAEDWRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1P7</accession>
    <name>A0ABR1V1P7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661832.1">
        <property type="nucleotide sequence ID" value="XM_066816140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049200"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="104" mass="11754" checksum="CD1DDF5AFDC8B256" modified="2025-10-08" version="1">MHAVCPIESPFRSAELLSCFRTCSVEVRRQIPVKIEKRHFWLERDGRETGFTADREEYLERIQPDVGPCEPDAKLVCNGTRNSVVFELSALRGTLADDFEGAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1P9</accession>
    <name>A0ABR1V1P9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_011856</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661863.1">
        <property type="nucleotide sequence ID" value="XM_066816171.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049231"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039121">
        <property type="entry name" value="NUDT19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12318:SF0">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE NUDT19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12318">
        <property type="entry name" value="TESTOSTERONE-REGULATED PROTEIN RP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="48"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="42884" checksum="E2FBCA735F7163EE" modified="2025-10-08" version="1">MYSTDAKQQPPKGPPAEPRPSSSIILLSHTNQVLLLRRVKTSRSFASAHVFPGGNLSGVPRRARRAAGRRGGAAPGRSGVPAGRHPGDVRGERDPACAQEEGGAPPGDDDDEGRLLVLSARERDEARRAVYGNEVAFTEWLDRVGGVADIGELLLHLGPQHQMTLDVCFVLTDIPDNLLPFTRWVTPLATPRRFTTQMYIYMLPFPRNHPPLHLLPTPDGAEITTSAFEDAATWLARQQSGDIILFPPQAFLLTLISQFCRGPPPHSSTPTPDTDYYQKQRDELTEFLRRVPTAEKPRSLKNPTSQIPWADKCISPVTTMMTDDGRILLSLDRPGPELKGTGRGGDFERVVLVRFEKGTARQVEVMDREEAFKTLRPAAPKGEAGKEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3T5</accession>
    <name>A0ABR1V3T5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662603.1">
        <property type="nucleotide sequence ID" value="XM_066816911.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049971"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="282" mass="31277" checksum="D49D93FFC14A7E43" modified="2025-10-08" version="1">MVNMDTNNGPLPTYFEHSWATLSSIGLINACFGFMVIGIVGFPVIATVPIVVLTASALANGLCYFAYCTEYPKTNTIVASAFDDVFWLIQEAGLPFYSDAILSRMLYMRTKLAFMLTFWTLMLGIVALRTMILTERVRYLMGDSSTAELQTLINRLHMGSFISIAVIECISSALLLLKFNSARRISVKAALQSGTGVLFSYLMHRGHEGRHIFVPSHGAVCVFGGRPARSIRVYAGMHVSSHVTNYSIDILASRLMYDAHNPSYHRENRSAPQDGAFHANYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3V2</accession>
    <name>A0ABR1V3V2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662620.1">
        <property type="nucleotide sequence ID" value="XM_066816928.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049988"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF17">
        <property type="entry name" value="CUPREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046816869" description="Extracellular serine-rich protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="31222" checksum="E9582B0A070334EE" modified="2025-10-08" version="1">MQFSMSLAVFAAAVSALPQPLAVRKEQEPRVMSPQEAAHEALKAAGLRKGDFGTEAAAKIIPVIIGGQQVTMVPNLVTAAVGDIVQFQFANGNHTVTQSSETAPCTPLQNSLPGAVHSGHIPFNDGQTTVGTFNMPVLTTEPMFIYCATGPHCQLGQMMVINPKTADQVVQYFKVSNQAKANVDAKTVAGGTVAQIPLAQAAFQPAPPEDKGKGGAAPPPAAPPAAPPGLFQGRYFIGSTSSPAAPPAKASATSPAAVSPAPPATTAPPAVANPAAPAKPAGTTTTTITVQPGAGQIPAAGATPVAPAPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4M3</accession>
    <name>A0ABR1V4M3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662897.1">
        <property type="nucleotide sequence ID" value="XM_066817205.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050265"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF82">
        <property type="entry name" value="FAMILY CHAPERONE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G08575)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="487" mass="54301" checksum="282C59C7BFFA3CE3" modified="2025-10-08" version="1">MSSDMDGHPPSGRTLVVGIDFGTTYSGVAYGVTENPDRTIPCQTWSSSKTDGTVTGGVKVPTTIRYLQQRGEFEWGFQIPEDNVHPDDIMRWFKLGLQPPKNRPDEIRNLLARHDSDRLVKDYLSGLGENILHFLRTSSRLGENDVEMFIRESAIQVVLTVPAVWEEVAKRKTLQAFENARGLGGLGSVTLVSEPEAAATYALHNMIQESSLEVGQSFIVLDAGGGTVDVITYTITALHPVLQVREAAAGAGDFCGAAFVDKAFTDHLQATLGNEEGFDNELLGRALPVHGLANNQEIGIRSGRLTLRAFDVHAMFEPYILKTIRLVKDQIKHYGVELSVAYDREQHLGLENKRHWDGMDGCWRVDAMHWFIRRGDRVAESKPYYHHLSQASKVSHGRPGTIDLTIYSDSKSDEAPVARNGNVEVLSHLRANFRSIPTDQLPVVRGKDGLDYYVLSCDIEVTYRSASTEYTLIHDNHRYDTVTEEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4T9</accession>
    <name>A0ABR1V4T9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661767.1">
        <property type="nucleotide sequence ID" value="XM_066816075.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049135"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="230"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="650"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="757" mass="83745" checksum="33A8DF446B8809F1" modified="2025-10-08" version="1">MGSDQSDGVAVTEPEAGGEGPGTESGTTALWKNTPGDFCVSAPDYSRTDEWPGLPGLHASIAGTGCDFCRFLATTALASAEARQWLEETEVVGALKLSVRWLAQAQVNDDESVAGWLFQVLVWDNDWEYEVEPPFDDGLLVLSFPVTSRSEEVTKSRLFPPPVESSALERAPVEFLRTTLAECAEHSRPETKTTATPVFLPTRLIDVRGELPRIVELSNAPLDEEEDRRYLALSYCWGGASQLLLTRETEADLQAGFSLEAESLAPTQRDTVALARALSVPYVWIDALCIRQGDRADWEAEAANMGRVYGGAYLTVCSVASASCGGGVLGPQLRGPHHNTSRPGGGSVRGGRGTYAFQPLMWSFRSDDAENNEDENDEDTNNSSSNNNNWGQFSLGNSHWSTRAWTFQEMMMSARKLYFTTSGMHFVCGERVHRSEYPYALERETFAEVGKYSIKDNFGLEEISKMEDPDEIYQEWVYWVVMGYGNRQTTNPTDAFPSLSGLAHMFAPLLRDEYVAGLWAKRLASGLLWEPDGTLESLVSYYSDPGPAASYIGPSWTWVARGIVHQETSSFYLPDFVDECEALSAVCVPKGSDPCGELLSASLHVRARAYPAALGCWPAEYWDDSVADFRLQREAGSPSIRCVFDFQTGAEDENDEGDDDEDQAEEEGEEGEEAEDAAALQGCVFILMASYYCHQYELWKLAGLIVHPADDEDDAKGKGTRFIRVGRFTSWFESSEQDIADIREIFGQYGSRDFEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4V2</accession>
    <name>A0ABR1V4V2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662977.1">
        <property type="nucleotide sequence ID" value="XM_066817285.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050345"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="175"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="725" mass="81717" checksum="7922EE454CC15C38" modified="2025-10-08" version="1">MPASISSSSAPAAGTKRQSLGVGELQRNRILQDIHDHIGESRYRSYVDPDLLKHEVIDPVLQNDFDPQVQIRGILRALRDTLTFKLALQNIEPPELRNQVKAFLEGDTAEEVVNRKDFKFPGSHTIHHPAAAKEDQTSAVKQSLFAVLKNILLKILNVKGLVPTQIEFQNWGQTVKNTPQYTFVPTTVLGVQNLVRWAASNNLLVRCAGYRHSWSPIFSQDNNVLVSFVGLTQVTSMPDPMSLEPGDFTGAMVPGMSEFKTIELKEQLGPKKRLCRIGAGVTNEDFRRWALANKTWALPVDVILVEVTIGGVNGPICHGAGRRHQTCSDLVRRIEYVDCHGELRMVDDPELIKAAAGCFGLLGVVTHITFELDAMTYAVLEPRKMDIGLAIPPVNKEVIPEALRAEWFDKADADTQLKAADADFENRAENDYYSEWFWFPYQQKAWVNTWNTADVAEVDADSVWPEYPDPATVFLQWVQGWLGHIMTSSKLFGKIPGSWQAQLLAINGMASLEPKAGEDKEPTIVTPLPNALHFQRGIQNMRVRDIEFQIPIPARTDDDSRPDFTVVKRAWWDAINLVYDIYNEDGTAPMRLTLEMRIMGGSNMLMAPQHGNTWGTASIEVLTVPDAAHDGEWAGYVQRMSDIWMSYTDRHGAKLNVRPHWAKEWDGFQLGGMDARKYLKTVAYKDQIPKFRAALAEIGKGQNWTLEELKNRFSNELWDELIFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V552</accession>
    <name>A0ABR1V552_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013076</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663082.1">
        <property type="nucleotide sequence ID" value="XM_066817390.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050450"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="169" mass="18973" checksum="7C485961A3404A3F" modified="2025-10-08" version="1">MASATTFYDFKPADKKGNEVDLSEYKGKVVLVVNTASKCGFTPQYAGLEKLYKDIKEKHGDDFVILGFPCNQFGSQEPGTDDDIQSFCQVNYGVSFPIMGKTDVNGDQANPLFEWMKNEKPGLMGLKRVKWNFEKFLIGRDGQVKNRWASTTKPESLEKPILEELATKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5D5</accession>
    <name>A0ABR1V5D5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Galactan-beta-galactosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_013153</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663159.1">
        <property type="nucleotide sequence ID" value="XM_066817467.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050527"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925">
        <property type="entry name" value="GLYCOSYL HYDROLASE 43 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925:SF39">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047522648" evidence="5">
        <location>
            <begin position="25"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="518" mass="57674" checksum="5AB0FBFF4E72566D" modified="2025-10-08" version="1">MATTMRLTFARLIVLCCWAVLATAKYIVPGARWHDTDGNLISAHAGSVSFDDATGKFWWFGEYKVESQTEGGGVSVYSSEDLATWAYHGLALEPIEDHPYISPDMIIQRPKVVYSGGQYHMWWHADNSSYGLLLQGLATSPSVGGPYTFANATSPLGNWSQDFGLFTDYKDGRSYALYSNGDRREARDVYIAAYDEGVSALEGVVHRFDKYDLEAPCIVQTESSYYALMSHKTGYRPNSKFPLCRNASNFSARTESCIRNGRRSSFTECRGVPCRFAGRPLVATLDRGALNTRGFNSQSGYTLTIRGTKKTTYLYLGDQWDSNSLWESRYIWLPMRIDDEKKDLQIEWHDVYDLDVKTGDWKPVKGETYFGKNATTKGNAFKQEANFASDGIILTGIYGNDSTVTFSGIKGTGKPQWVSFYYQNTDDMGFGDQPGGSPDRIKGAWQLRRISSVVVNGDEANVQTLFQRDTHKGIILSTPLLLTLKKGSSNTITVGGLSNGVDYKGADLDRIIVYPPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V604</accession>
    <name>A0ABR1V604_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663384.1">
        <property type="nucleotide sequence ID" value="XM_066817692.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050752"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="20"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="512" mass="58049" checksum="89FED422DCABB704" modified="2025-10-08" version="1">MRLINTKTFLLESIYTQVPYAILSHTWGPEEISFQEWEVVHDSGAIQGQCPHTQKMSRPNVTRKKGYEKVIGACQQAARDGIQYLWCDTNCIDKTSSAELSEAINSMLFTTIHRKALEDSSSIPTFSIAQRMSWAADRRTTVPEDMTYCLLGIFDINMPMLYGQGTKAFLKLQEEIIKVSDDHSILAWDHTNLPSEPTSGLAKSPAAFKTCGDISRCNDIKQSSHAITNLGISMRLELMRTTIPDVVLAGLNCCRALYQPQTQKTTSTRLGREEFQIWIPLLATGNKGDHRWLRSHTPTSKVYLDAQFQVMGNSTTCDLFILTELRTQQIAASVEPQILQARYCPESSGFLTRIGFGDIDHIQSYLDVYDVRGFTITTMRRCRSRDFSHQLVSSGLFSVLFSAVWGLNGSPVTTRHTVIQARPSDIFAKTRSENRWDILYDQHGQHAQTVEELCVKLSTLHEEVLAYFPEGSHHYSDKAWPLVQQSESPLHDFRRRSVLPVKVIFRDPTHIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6H7</accession>
    <name>A0ABR1V6H7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphoribosyl transferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013553</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663559.1">
        <property type="nucleotide sequence ID" value="XM_066817867.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050927"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005919">
        <property type="entry name" value="Pmev_kin_anim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF25">
        <property type="entry name" value="PHOSPHOMEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04275">
        <property type="entry name" value="P-mevalo_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="282"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="869"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="874"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1133" mass="123447" checksum="EBDD63C7A65F8539" modified="2025-10-08" version="1">MASLTSLIETLKQRANCTDPPFTQPLSDAQYSDGFDSISQGAGWSTYQNFIIPQLNRALTPLFNSRDRVSVLEIGPGPKSVLGYLPGHQRQKITRYTAFERSELFATRLENLIGQIPHGDEQDEKYDIVLFCHSMYGMSPQRKYIEKALELLVPLPAQGLVVVFHREETLDVDGLVPHRTASFSEAFLSIDDDDETLDSFAAFVTGSAVQNDTAMGRAIQYEWRKACRDLGRHDDGAHQGRLMFGTPEVMKAFTQHAAALPQLIAKVPCVTGDRMVKNREARLHQPAAIIRPTEIQHIQECVRWATEHSTNLTVIGGGHGGQCVWPDSVAVDMDAFNHVDIVMPDKANEEQAQPLLVVGTGCKAGDIISKASESGLTVPLGSRPSVGAGLWLQGGIGHLARQHGLTCDAIVGAVLILCVGNVPVQHRPADAIRPDNEANLLWAIKGAGTNFGIVLSVTFKSFAAPTYSVRDWKVPLDEGPEAVCLLRKFDEAAKELPRNCSADAYLYGEADKLYLSVTMYEASTNTATTAHTTTSMQNLLGPEIDLKIVDGTGLFDTEMYISGMHGGNGGGKTSSIKRCVFLKAIGSKKIANLLISAMETRPSPCCYLHLLQGGGAVRDIAANSTAFGCRDWDFACVVTGVWSRDQDGTETAQAAVRWVYSVVEALLPLSNGVYGADLGPDPRDAPLAIKAFGPNRPRLACLKKTFDPQNVLAYACPLLNEAPREPRLIVLVTGESGAGKDHCANLWACVFNRQRKLKARVASISDATKREYAAASDADINRLLYDRAYKERHRTTLTEFYEDKLRGRPRLAEEHFLDVVYDAANSEVDALLITGMRDESPVSGFAHLVPDSRVIEVRVQASQATREIRRGQSCLDSASYSDDNDGPNPTTSITALDSDRPTFVFDNDAIGEDEWPIEFFAERNLLPYFSEKLEKLRTMVRVIPDFPQPGVEFRHTLGIAQQTGGLELCTSLLQSHFNHGDWTYVDNIATCEAGGYVFASALAARVGVPLALIREEGKLPPPTVSMAKSSPSYITSMSAESDDKKGEETNGKRIVMDRDAVARGASVVVVDDVLASGATLCAILHLLGEAGVSQANISVLVVAEFPVHRGRQLLLRRGFGGVRMQSLLVFGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6K7</accession>
    <name>A0ABR1V6K7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663563.1">
        <property type="nucleotide sequence ID" value="XM_066817871.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050931"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="122" mass="14068" checksum="61236B34F767E5A0" modified="2025-10-08" version="1">MKHLLKDVQDHKGLGLKEIHKLVSSLYADKEAITNLTPEKWVLKLFRDAKRKSKEGEQTNLGEGDTAKTKKLQKKVAVAEEKGEQVNNNHNNKPHDLFADEPMDDEEEDGGYESEPDEWWKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6V6</accession>
    <name>A0ABR1V6V6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663678.1">
        <property type="nucleotide sequence ID" value="XM_066817986.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051046"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="45"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="217" mass="24873" checksum="8B4E70925A8F3C38" modified="2025-10-08" version="1">MRLSRAKTDQFNNKNVVGFDGLVYQTKKRNCDEATKQNIRRDETIAELARRVRELEAQALDEYDERDETIAELNTTIAGLNARIRELEVELNDTQTANAGLAEERNNLTRARDALQEENRSLMRVNIEQLYTKARLVAYIREASGHLHLEVVETWIRSALKPELVELALALFERMGNPQSDDPQPDNDSSQSSSSSSTASEEWFNESPRRSKRLRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V754</accession>
    <name>A0ABR1V754_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methionine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_013752</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663758.1">
        <property type="nucleotide sequence ID" value="XM_066818066.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051126"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="METHIONYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="63"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl-tRNA synthetase anticodon-binding" evidence="10">
        <location>
            <begin position="477"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8067005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="589" mass="67338" checksum="F7AB5CC82C44DEA5" modified="2025-10-08" version="1">MQGFLTASALKLPRSSLHTAIRAGWVCFSCRRNGALRPTTLPSYRRSFSSSPARRIDAAPKPYYVTTPIFYVNAAPHVGHLYSMVLADVFKRWEVLKGRQAYLCTGTDEHGMKVQRAAELQEVPPKIFCDGNAETFMDLAQKANMSNDYFIRTTDPDHRETVEFFWGRLRERGYIYESKHEGWYCVSDEAFYPENMVEKRVNSMTGKPFIASIETGNEVEWTEERNYHFRLTDLRDRLLQFYKENPQWVVPASRMADVVSWVQNNLEDLSVSRPVSRLNWGIPVPDDPSQTIYVWVDALINYLTKAGYPMWTPGSENALGWPADVHIIGKDIVRFHCVYWPGLLLALDLPLPKRVLSHGHWMMDSRKMSKSIGNVVNPFFAIDRWGVDTMRYFMIYNGGISQDSDYDNSFIVERYKRGLQGGVGGLLNRVTRSKAWNVRSIIQKAHEGGYNALVGECEPMQTEITELREATDALSLKALDFFEEQLNPGRALKEIMEVVFQANRLLQHTEPWNLVKRGEVEAAHQIIYHAAEALRVAGILLQPFMPEKSAGLLDRLGVDQGQRSFDHARFDSDSAYGVSTVPLWGRRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7R9</accession>
    <name>A0ABR1V7R9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663961.1">
        <property type="nucleotide sequence ID" value="XM_066818269.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051329"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="233" mass="25245" checksum="B95F0D06B3151B69" modified="2025-10-08" version="1">MGQGTAGNGMPGGASSYTNINDWGHQSIQGEHFQERQHPQQLQQHLTTPVQLPMTVHQAAAPKKKAAESLVAVASADAAAGNPAEAARILTIVAKERDNVALMGRAAAAVAVAVAPALPEPEPEPEPERASEKAGRDLDRPIQSLTIPDILTVAKMDAVRQREFRQLARDATESRDGAGDDATRHHWQLTIDKIENLEAHPPAIPQEIIDIMGRPVYEIKTYEMVSKAERKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V807</accession>
    <name>A0ABR1V807_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664087.1">
        <property type="nucleotide sequence ID" value="XM_066818395.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051455"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8067334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8952" checksum="0A1A1012E5A211C4" modified="2025-10-08" version="1">MCHIYEYRQVQCGQCNQYHGEKTDKDFMEQCRTAYRLGGFGTCKKSVQKQTVKRYKWKDCENCQARQDVHAMWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V814</accession>
    <name>A0ABR1V814_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014084</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664090.1">
        <property type="nucleotide sequence ID" value="XM_066818398.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051458"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF382">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539423" description="Amine oxidase domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="176"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="685" mass="75741" checksum="7F3A70334A5651D7" modified="2025-10-08" version="1">MRYSLAASLLVSSAACAPYAPLPVHLETRTEIDSRVANVHVTFNEPVEGELTYTYGRHCSGTHQLRDAHHTVARSNSNSESRLVWLMPKDAESGGCLSAWDSNGALVGRSEPQRFQTVKKRDLRKRDGGIAMTQDMGIDTWGPWFDGVKLLENKEISAVDAEAAKSKEVAIVGGGMSGLMTYLVLHQSGLSNLKILEASQRLGGRVHTEYLSGGPFDYSYQEMGPMRFPMTVSVANETYNVTDHQLVFQLAAEMNGLNGHDRNLSVDFIPWYQASPNGLSYNNGFKLPETGMPPTLAQIKQNASLAAPAPALDETTQKLQDAITKITSNETMMIEIATNMHKAHKDFIVNGLGGKGGEVWSEFAYMVNYLNATLNQTDIVVGSSADSSFWNSLYDNVYFSASTWSTIDGGLSRLPLSFHPLVDNVTTMDAHVDQVEFLDAEQRVRLSWKQKGAKDAAYQNATFDYAVIAMPFSKVKLWRLPMLPTTIKNAINNVPMESACKVALEYKTRFWEHLPTGPIYGSCSTSTDIPGVGSVCYPSYNLNGTDGPASILASYASGDWAVRWLSQTEDEHVQYMVDAMAEIHGDVAREQYTGRNNRRCWYLDPYEGGAWAAPTIGQHQLYIPEYFKTYSNMIFVGEQTSYTHAWIASALESGVRGAVQLLLELGLVDEAKAAVDKWMARWIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V868</accession>
    <name>A0ABR1V868_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinetochore protein NDC80</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_013248</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
            <location evidence="10">Centromere</location>
            <location evidence="10">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the NDC80/HEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663254.1">
        <property type="nucleotide sequence ID" value="XM_066817562.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050622"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.30">
        <property type="entry name" value="Ncd80 complex, Ncd80 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005550">
        <property type="entry name" value="Kinetochore_Ndc80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055260">
        <property type="entry name" value="Ndc80_CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057091">
        <property type="entry name" value="NDC80_loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038273">
        <property type="entry name" value="Ndc80_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03801">
        <property type="entry name" value="Ndc80_HEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24487">
        <property type="entry name" value="NDC80_loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 10" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Ndc80 CH" evidence="13">
        <location>
            <begin position="100"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Kinetochore protein NDC80 loop region" evidence="14">
        <location>
            <begin position="432"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="310"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="369"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="575"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF24487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8066501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="719" mass="82190" checksum="D7CD8C618845BAC3" modified="2025-10-08" version="1">MSQDTGLWSVRRPRETLGGINPLNSAIPHPASAMKRSNSNSGSNSHVRSMSGSRHSLAMSRPTQPMFGRSSSGTNLPEMGLSSSYASGSLPNRNSEGDARRSSVYRPHPSNNGPMSHQSFFQQAPQAAGVPRDPRPLKDRSFQARIGQELLDYLVQNNFEMEMKHNLSQNIMKSPTQKDFNYLFQWLYHRIDPAYRFQKNIDQEVPPILKQLRYPFERSITKSQIAAVGGQNWSTFLGLLHWMMQLAQMLEGYSCYRYDDACAEAGVDISGDRIIFDFLSSAYRDWLAMDDDAGDEDAERALAPHVQGMAEAFERSNSKYRSELDMLEAENARLLQEIEDMEKATPDPRVLDDHFKIMEEDKTKFEEYNALAMQRSDKYESRIAVLQEEYDKLAQEFKEAEDERRGLQREVDDQGISMQDIDRMTSERERLQKGIESAALRLEDVKKKVAEKEVDASRRLDELERLVDKYNTLAYQIGLIPSTAVNANGEQFELAVTVNESNFTGSMMNSGSYKGAMPETSERLLADPVTGYQPAHILNLDLRGSVKNAFMTLRKDISERRSAAMDAMMKDHDLLDGIKEAIEDKRSEVEALEHRVRAAEEEYERTKEVTTTQKLASDAQIEKMEKELAKMRAQLTESVQLMEQREMNTNIEYEQLTLRANSLREELHTEIEKMLNDIIKFKVHIQKNLEDYEGFVADELEKELGSDDMMKDDTRGVDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VBP2</accession>
    <name>A0ABR1VBP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Osmotin- thaumatin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664106.1">
        <property type="nucleotide sequence ID" value="XM_066818414.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051474"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045438091" evidence="1">
        <location>
            <begin position="20"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="178" mass="18617" checksum="420A5227A34EBB0A" modified="2025-10-08" version="1">MSLEYLLIYLLATARSALAAALPLWPTMPPVYNQTEIPYVTTICSTFQYYPSITSTSSSSSMVVAASPSAQDIGGATATTTEPPSLLTISVVNSHTAAISTTHNSNAGAPSPVSGSLMPGTLAAGATEAIAVPTDWAGIISVNDARYTPSDKNSLIEANYQYRSVERYAIADVDVSYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGS4</accession>
    <name>A0ABR1VGS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_010591</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664196.1">
        <property type="nucleotide sequence ID" value="XM_066814906.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047966"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF4">
        <property type="entry name" value="CONIDIAL DEVELOPMENT PROTEIN FLUFFY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="50"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="189"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="620"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="620"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="664"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8070388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="866" mass="94813" checksum="43E86B782E248AD9" modified="2025-10-08" version="1">MEEGPKSRSGHSSNPEHPTSTSTSEKHPAPSNNDAANKRRRGLGVVTPNACTECRKKRAKCDGQRPCGRCRAQKDVECVYEIPVRQSKENLRSEIDQLRRQQRQNDSVFSALVRPELWEEVLTRMRGGQSVENISEWLGSARGSNNMPQSNFSQPLLPLPQPKQGATSSVTLPPLAGMGYGAPGPGPGSYAPLPNAGANQAKPEYDHNSPWAFSSQDQSHSTRSNSHPDVMQWTADMAPNTRVGSWLQTQQSPAEATRYHGVDQIFAPIQSPEMKVPPDTWTNVTTDTNLVQHLLALYFCWEYPTFASLSKEHFLKDFLDGRHRYCSPILVNALLALGCRFSTQPNTRENPDDPYTSGDHFFKEALRLMYRENNHHNLMTIQALGIMSIREASCGRDSESWYYAGQSVRLALEMGLHKVDDNGDEDELAVQAATFWGAFALDHAWSLATGSLPQCSCSDVLGAPLQRSCEQPSNVRSVYKCFCELSELVHQSLYVLHSPGRPVTSRDLLNIYTQYLNWYDRIPEVLRLGHNFTPAVLFAHMYYHFAILLLFRPLIKLRIIGSSILPRDVCSQAADAIQGLLRSYSQLYTLRRTPSFVPYFVLTSSIMHLAIGASSPIQSATSPAAASNPSTAKPEGAEQHPHGHPSRPTTSSNSSDAGGGGASTPGRSTASSTATLSPRVTESLRQGISDLEEMAPCHHFAEQALHILRYLARKWHIDIDLSKDGGPSQDEVDKLVGPQTSSLNFFTPKVVENDFICAWGTPGDYDDDNAGGPAKTGVGKETGASTTQIDTGEHAGGVEAMEGAEATVGEADALDRMKETVGPGTVATSAKDIESMENPLFWPFPMQGRPILASGPKLQEAGFAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH72</accession>
    <name>A0ABR1VH72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA selenocysteine-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664346.1">
        <property type="nucleotide sequence ID" value="XM_066815056.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048116"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="190" mass="20868" checksum="472D5DA80756039F" modified="2025-10-08" version="1">MLAKRGLDRVFRLNRTLGAALDRGLVDRRDTRSPEFSIFDGGDFGHEVNGSLAWLLCSKRRFPSWESTKDLNPRTSKPATGGGQSCGYDLVCFPSCKSARSWASDQQTGHSVLCRTLGACPFQDRPAGSSPAKTPGKVVKRGGQGSSGGRAKRPKTQHDAYDDLDDIEDFDIIKKEEDDEDKKVIFVDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHU5</accession>
    <name>A0ABR1VHU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010925</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664530.1">
        <property type="nucleotide sequence ID" value="XM_066815240.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048300"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972:SF1">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972">
        <property type="entry name" value="MONOOXYGENASE ASQM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="6"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8070722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="124" mass="13634" checksum="7CCC5EC0642172B0" modified="2025-10-08" version="1">MATPSIAIIGAGPSGLALARLLECRGISYILYERDASAAVFDRTGGTLDIHASTGQRAIAEGGLLAEFEKYARYDASTFRVWDRHGTQYIQHERGSDFPEIDRGDLRRIYLDAIPEGRFAGERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI76</accession>
    <name>A0ABR1VI76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664706.1">
        <property type="nucleotide sequence ID" value="XM_066815416.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048476"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="150" mass="16433" checksum="89A6F52087D97DCA" modified="2025-10-08" version="1">MLTAEIPAAIDLARFNELISSNLQDMPHGQAVDVLRSTMNTTLHMICCGYANVSFRNVSHDDDEAQSELESILVSSPSKGQAQDPCPKTPYPCFWTGGSQTIYTTGLMPRFGHSGPTDYAIHIHGHAAWPPHAECQQHQMKKGVPCHAMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJG3</accession>
    <name>A0ABR1VJG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665163.1">
        <property type="nucleotide sequence ID" value="XM_066815873.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048933"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="307"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="248"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="724" mass="83314" checksum="FFBB99F5D98DF740" modified="2025-10-08" version="1">MPTTDRAPWQAVEDASDSDLPGRAGSTAAQAGDPTVPDHASKARERKSTKTHERRRHRDEVDRSGDYQAFPLPSLSRQPPRDDHGGPSSDALNNAGPRIPGQRHRREQATLNRLQKQSDYDVGFTDIHGMRRPQLSYAGKPADAAFAEGPPRPTGETVRYRQPFNPVNQFERIDEEGEFSGPYFGGAPYYGRQSYPTQRFNTSQPSFSQQYQPVNYGNQSYNLRPNDPPTARWQSDQRADPQADRRAAPAAPEAPEAPEAPVRVEAQWGNKGPDSEWLKVMKELEDNRNELAQKDDIIKKYRVRELEKDMLHDATEKQEQANKLKEQAKLELETVNQKRIEEQKEEMARLEYKNKVLQAAQEAREHMEQKLRDEERLRKAEEQKVLSLEIDMRRRIETEIAEEAERRKREVEKRMYLEREIRAQLMAERREDEERTLREELRKQHIEKRLEYEFEMKRRRADELQQYKEGIEAKVRMEANQIIGSEQRKLDMEKMRLEIQQGTERVIRDTLQGDDAVSLHSDSIHVDDYLDPDQSIVDFNLQNTYPHSRMDSRHVYETNRQGISHPFPNLDPRRPPEPVAPPMGPVEPRFAWNGPNANLGYQRLGWGAPAPAQTTSGRPASVGNHLNNYSGNPFGQHYFSHLGSQQQLHMPNPTYRANPSNLMHNMAPEPSLSGFSSDLNLRRHPPPIPQATVLIRNQGREPAAGSAIHNRQQFPTLCQNRVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJK3</accession>
    <name>A0ABR1VJK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011620</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665225.1">
        <property type="nucleotide sequence ID" value="XM_066815935.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048995"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF8">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="66"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8071417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="51569" checksum="EE2615FA1FA68282" modified="2025-10-08" version="1">MQERNHDDGIFQASADTKTNGSTDLSEKDGVKMTAPHSQSSVDNGVGQITELEAQKAALGDAHFHRLGWKRLTVILIVEAIALGSLSVPSAFATLGMVAGVILTVGIGLIAIYTSYIVGQVKLAFPEVSHYADAGKLMMGRFGYEVIGAMFTLQLTFLVGSHTLTGTIAFLNITNNGTCSVVFGVVSAIILLALAIPPSFAEVAILGYIDFVSIIAAILITIVATGVTGSHAEGGLAQAAWSAWPKENVTFSEAFVAVTNIVFAYSFAVCQFSFMDEMHTPKDYVKSIWALGLIEIFIYTVTGALIYAFVGVDVKSPALLSGGTLMSKVAFGVALPVIFISGSINTTVVGRYIHGRMYKNDVKRFINTKGGWISWLTLISAITLIAWVIAEAIPFFSDLLAICSALFISGFTFYFPAMMWFMLIKKGNWYAKENIWSSIANAVVFIIGLITLVAGTYAAIVDIIQQYNDGTVRGAFTCAPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTE1</accession>
    <name>A0ABR1VTE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665476.1">
        <property type="nucleotide sequence ID" value="XM_066813514.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046574"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="245" mass="25101" checksum="FE0AF4AC9B4A7CBC" modified="2025-10-08" version="1">MVVADLALTPISTPFPLHDPSGVLVVLTTNTAVSATGTRDDGVASEACSDEALPPAPAGATTRSAPPRSCGARLARTRRPTASTSLLPRTTAVNDVIGPALRDDRRHCHAVQHRLHARLVRERELEAEGQHVALRRGGQPQDDGAAQLKVPPLRAPVVAAVHEVHGERAARPGGPGPGVGLGDVVVRQQGLEGADLPGAEAALEAAVLDHDGGLGRGAGRRARGGGGGTRVTWNSGGTAWASWAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUN9</accession>
    <name>A0ABR1VUN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Homoserine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009631</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665908.1">
        <property type="nucleotide sequence ID" value="XM_066813946.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047006"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001209">
        <property type="entry name" value="PRK00175.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF16">
        <property type="entry name" value="SERINE O-SUCCINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="142"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="398"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="525" mass="57067" checksum="A9782A0657894E8A" modified="2025-10-08" version="1">MRAQRFGATALRQASGLLQTNTERTASQIVRARLSPRRAAPLSSSSARSLHSQTAKRNEATTPQGDASNPAMAFPCLDALETRSATLEARSLSTGPEPAYTTGATESFRCTKPLLLDWGGVLPEFDIAYETWGKMNADKSNVILLHTGLSASSHAHSTESNPQPGWWEKFIGPGGCLDTDKYFVICTNVLGGCFGSTGPSSIDPADGQRYATRFPILTLEDMVRAQFRLLDGLGVEKLYASVGSSMGGMQSLAAGALFPSRVGRVISISGCARSHPYSIAMRHTQRQVLMMDPNWNRGFYYGKVPPHAGMKLAREIATVTYRSGPEWEQRFGRRRADSSKPPALCPDFLIETYLDHAGEKFCLTYDPNSLLYVSKAMDLFDLGRETQSAAATRRAERAEQIESGASPARPEASCSLTLPDSPYLEQPDAKIVDTTTTPIEVASRPPDDLIAGLAPLRDIPTLVMGVASDILFPAWQQREVADSLRIGGNRKVSHVELSEEQSMFGHDTFLLDLKNVGGSVKNFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUW5</accession>
    <name>A0ABR1VUW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme Q-binding protein COQ10 START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665979.1">
        <property type="nucleotide sequence ID" value="XM_066814017.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047077"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07822">
        <property type="entry name" value="SRPBCC_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="24210" checksum="8859077CD1D02411" modified="2025-10-08" version="1">MKPTEIPLGQAPTFAAETIPTPTYGPGGSSTAIFSTTIAAPPATCLAVALDTSTYPSWGQWIPRAVVETPAPASALDAVPAALAPMLPTDKDKRAGLLLLGAQFYFEVHMDPDSASSRKTYLEVTRLEEFVRDADGGGGGEKKGIRVAWKTQGDPWHVRAERVQEFVDDGKGGCEYYNYETFHGALAWAIRRFVAGQLSNGLRLWMEGLKKEAEAKAAAAAALPTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV54</accession>
    <name>A0ABR1VV54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transcription factor S-II- central domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_009792</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666069.1">
        <property type="nucleotide sequence ID" value="XM_066814107.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047167"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13749">
        <property type="entry name" value="Zn-ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035100">
        <property type="entry name" value="TF_IIS-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF0">
        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006704">
        <property type="entry name" value="TF_IIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="9">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="10">
        <location>
            <begin position="135"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="8">
        <location>
            <begin position="252"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="85"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8075129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="294" mass="32699" checksum="D9EB37B0732AB315" modified="2025-10-08" version="1">MLDAREVANRVKALQASIGKSEPADIMSQIETLKKEVAPTEEMLRTTKAGLLMGKLRQNANKDIARAATEVVAKWKKCVEQEKAAKKGKASASPVPKPASPAPKPAGNKKKFEGDPEKRKFQDDGVDVKRTGSATRDNCIGLIYNGLAYRSTEPVDSVLQRAIEVENAAFKAFHGESKEYKEKIRSLFQNLKVKSNADLGKGVMSGEIIAEKFVRMSSQELMSAEMRKQNALLEEENMKKAQIPIAEKSMSESLECGKCKKRMVAYSQAQTRSADEPMTTFCECMNCRHRWKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVB9</accession>
    <name>A0ABR1VVB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009858</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666135.1">
        <property type="nucleotide sequence ID" value="XM_066814173.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047233"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="115"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="862"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="695"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="921"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="982"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1083"/>
            <end position="1096"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1096" mass="119877" checksum="28788F3779D04568" modified="2025-10-08" version="1">MLWTPWATSVPSVLVVCAVLAWWFTEPKTAHLNAIVTIGLMLFFWSIAPELAQETPTWLYQAALGYLATSELDIFILRHFNMLITGLAATWLAYRAWQVLRKPVPELIHVLGVEVPDPPDVSLAGIRKDAATLNWTRPHANSSVAKFLIQVNGVNVGESSSQETAITVTGLKPSHFYNIRVIAVSHSNFQAGSRSIRLRTYNKDGRPETGNDRVPASWVPEDQPSSSAESHDDDGNIRVPTAAVETASIPESTAAPMQISSSGSVTRRNTLTRKHSPSTASMDQSVKDALDRVPEGSLVELSARFENIRKDTEESLAQLEKDERDHQKWLDELTEEKKTKKQILKEKDETTNKYKAEVNSTDRAMRSTQTRKTNVEKRLRDKENERKKLHDDIARDQIEALQASLAQEEAELREKGKELKEAEDQRKRLPGGEESEEWRERDRQTQREWEGRCRDLNRRIFFLNRKLKAQDDYELVLRTQLATAQQSNLGFSYAQANASGVDFDLANQTQLKRRSRTGNSMQGAAAPSPSTSYAMEDRQPYVPANGFDGGFPTSRAPTIPPGFGASAFPNFSDVSAPLDDEGLQALTAGAPLSPTATSLLPATLFDTADDDFPPTRPSRHGTFGQPIAMSSPHGSAQHLPFSHYGGDVSERASLRGDYGTASSPAAPSAQTNRFSFWPHRQNKSTNEPPPLGSLKSAQSQSFPRQTDENDAFPNKRRISFSSGWGMFNRNSAGPAVGDNGLSGLRGVTSRRGPFFAGNNASGSIFPERDPSSPRPLSIASSELPRPSTESGPSMWGRSHPSRIWSPEGADPWSRTVSRRPSIHGSPSALKTTLADAEDEILDESEIRQPPLGVGVIGSRPSAAKALKQSLNPNAPSFMGMFRSKEKDSREGKDKVKAKGKDKEAHREVNPRVSITSSTWEPTERPSMDESLAESRESRDTLSVSESHESLSLDQSHSNTPSEPAHGLGLKDPESGLRKLLRKGSSSKFSLSSIRGSKKGPGSVSNSDKNLNLERTSIDIDEHGQDSGTGAAGAALLGRSYDSVNSSPNIGSVGGGRAKDGRASWTGRFTMKKKQGKDKDEESAPSTPTLGATSEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVP2</accession>
    <name>A0ABR1VVP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NAD-dependent deacetylase sirtuin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009971</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666248.1">
        <property type="nucleotide sequence ID" value="XM_066814286.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047346"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01408">
        <property type="entry name" value="SIRT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="16"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="322"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="443" mass="47926" checksum="4D4CAFCE10B11C40" modified="2025-10-08" version="1">MGNENSTLIDPDTPTKTLKNRSLRAVADQIRNGGGKRIVVLTGAGISTAAGIPDFRSPKTGLYHNLARLNLPHAEAVFEISYFRENPYPFYMLAKELYPGKFHPTISHAFIGLLAKRKLLRMLFTQNIDCLERRAGVPGDLIVEAHGSFATQRCIDCKTEFPDDEMPAYVEKGQPPRCKQKGVPDIVFFGEQLPSAFFDNRDVPSESDLVLILGTSLTVHPFASLPDMAREVTPRVLFNKERVGTLGHRADDVICLGDCDSGVRKLADELGWRDELERLWRGMVGDEEADRQMQQSNVEREMDDEMERLVQGVADRLDISGPQADEDLTANDDGQAGITKEAPTVAAPAETAGTGSAEKDNKEDSQEKVTSQEAGEGGLPAKDSLSNQGDAAAVAGTETSSGGSSSTPQEVKPKVEDAPKPTASVDAASEQSKGTAASHVMKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWY8</accession>
    <name>A0ABR1VWY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666689.1">
        <property type="nucleotide sequence ID" value="XM_066814727.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047787"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45763:SF46">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45763">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="39"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="307" mass="32663" checksum="4AFA35704827A711" modified="2025-10-08" version="1">MATRHPKPTSAFVLPSGRTLGYAAYGSPDPAAPTAFYHHGFPGSQGEAFGYDAAARAQGIRLVSVERPGMGASTFQPGRTLLDWPADLLALADHLGVKRFAVLGVSGGGPYALACWHRLPRDRCIGVGLVCALYPTSLGCSGMLIQTRALLTLCPWMPTPVGWILDAMLGGTARDLAHPEKLELALVDALKNKPANDRAMLEREDVRAALVSGTRGSMISGGLGSAWDGLVLGSDFGFKLEDVKIEPGKVVMWHGAKDQNVPAHMAEKAAALMPGAELRLSPEHAHIDLPYMKADEVIQRLKQILGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX09</accession>
    <name>A0ABR1VX09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009097</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665374.1">
        <property type="nucleotide sequence ID" value="XM_066813412.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046472"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="24"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8074434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="354" mass="37408" checksum="CC4CDB5DCB17E464" modified="2025-10-08" version="1">MTQPPPSVPDQMQAVQVIKHHEPYELRTVPVPSSAEDDLGPNDLLVKVAAASYCHTDGMVAAGVFGDKLPVTASHEGSGTVVRAGSASGLEVGDLVMCGLPFHPCGECGDCRGCQAQQEQYCPRVQGHVGVHMDGCFAEYVRVDARFTTKLPRGVSLLSAAPLACAGRTVWRAVRQTELQKGQWVAIVGSGGGLGHLGIQFAKKALGLRVLGIDARDEALELSRGFGAEAVLDARRDKEEVVAEAQKATGGHGADATIVLSDAPGAVALGCAVTRMHGTVVQVAQPDEVSVPFQELVFRDIRLQGSLLCSPAESRAMLKAVAEHGVEVRTNVFRGLESIEELMEMIDAEKQSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7U4</accession>
    <name>A0ABR1W7U4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GANP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667033.1">
        <property type="nucleotide sequence ID" value="XM_066811691.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044751"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF4">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="2">
        <location>
            <begin position="278"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="518" mass="58454" checksum="B137707A2ACC6FC3" modified="2025-10-08" version="1">MSWASATPPGTQPGYVSYAHGNFATSAPHPFATLQPSYSTFAMPSPSESRPRINADMVPFLAATAYTPVPVRQGFGQPYTLQPQYAAYANTTNPPPAPAAPPAEPQQQQQKIDWPDKVRSYVQRSFESKNMLPDVSREEMEAKLKETISHAKDAGIMYTTDWDSMPLPRSSAAASTEPPARATNHHNSKKRKSSDFSESDPSTGNPWRSNKKLLSLSDRISQPPGLDSKSLKQAEKAENRKQRFNTAEYKTYRSPSPPPPTGPILGTCTNLEKNYLQHILHQTLDLLKKKWRKENNYNYICDQFKSLRQDLTVQRIKNEFTVSVYEIHARIALEKGDLGEYNQCQTQLRALYASGIKGNAVEFKAYRILYFIHTANRTALNDAIADLTTADKEERAIKHALEVRSALALGNYHRFFQLYLDVPNMGAYLMDMFVKRERLAALANMCKAYKPDFKLRFITEELAFESDAEAAQFIIDHNGQHLLVEREDSIIFLAGNAKQLFETARADAHRRVDLKGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W872</accession>
    <name>A0ABR1W872_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667153.1">
        <property type="nucleotide sequence ID" value="XM_066811811.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044871"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF3">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="518" mass="57426" checksum="0E884D5E0C0D7FDD" modified="2025-10-08" version="1">MRFTATAGLATLAAVTVHTRELPKDEVIGAELYDTGIIHDRLMAKKIAHWESQEAMGAMNSSVWPRLDYTKCIDGFAEAIPGDPLHKFKCKNIDLYDFINHATLGSPNTDYRGKSGSSSWGWTDSESGREFIVSGMFDGCAFIEILPEGRMLNLGFLPVFMSSRVLTIDTSEAPVLFSNEHDLTGHFNETLPLGRSHNVVINEEANYAVAVGVTPRNISCMGGLYFFSLDDPSNPLPLGCDGQDGYVHDAQCLIYRGPDAKYNGRDICYGYNEDTLTIYDVSDKKDSKIISRTSYEGATFTHQGWVNDLNWQGIEEWLFMDDEYDEDDSAGPAADGYPVTYIWDIRSLEQPKQTGLFKGTVRGIDHNQYVVGDLIFQSNYGAGMRVYDVSSVPQDPTGNGVCEIAYFDIRPEDDGLPGGGSIEFSGSWSSYAWFKSGFIFINTIERGGYLVKMTKREACKPKSCYADDCLRALRASHIPGRLGESQEFCGEFTKTFVADSELGLLVFAYSYSMNTAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA91</accession>
    <name>A0ABR1WA91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxidative stress survival- Svf1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007775</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SVF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667432.1">
        <property type="nucleotide sequence ID" value="XM_066812090.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045150"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051385">
        <property type="entry name" value="Ceramide-binding_SVF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033394">
        <property type="entry name" value="Svf1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013931">
        <property type="entry name" value="Svf1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107:SF1">
        <property type="entry name" value="CERAMIDE-BINDING PROTEIN SVF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107">
        <property type="entry name" value="SVF1-LIKE PROTEIN YDR222W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08622">
        <property type="entry name" value="Svf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17187">
        <property type="entry name" value="Svf1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159245">
        <property type="entry name" value="AttH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Svf1-like N-terminal" evidence="4">
        <location>
            <begin position="55"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Svf1-like C-terminal" evidence="5">
        <location>
            <begin position="216"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8079957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="388" mass="42205" checksum="49F70BD7A2EAF796" modified="2025-10-08" version="1">MFNWAKKTLADAVGTEEPIYGPSAVRSVAEDAKTTPWTELSRQDQKWHTLGNTSVETQSFYLTAETGHVALAQVIYSNVAGVRVTSQFNSKISYPDPSKPHLWCSTALNDVDFSDDKVNFYAKDCAVELSEDGKTYAIKSITDQRCIVDLKVTRTAPAFVAGKDGNTLFGADLSKPWGSMRHSFWPRCVAEGTMVTEDGPINFKGQALFIHALQGMKPHHAAGKWTYANFQSAKYSAVMMQFTTPPSYGSTTVGVGGIAKDGEIIAAGCITTATHTKTAVDAETQWPEPKEIKFTWSGKTKDGKAVEAVIVGSFEKRLDRIDVMAEVPGFVKKIVAGAAGTKPYIYQFCPTEAVEMKLKIGDEDITDSGKLFSEATFISDTEPAATKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCY8</accession>
    <name>A0ABR1WCY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008194</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667851.1">
        <property type="nucleotide sequence ID" value="XM_066812509.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045569"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="19643" checksum="E5B5EAD07839000E" modified="2025-10-08" version="1">MAAAAAAAAVPAGPAGPASAAAAAPAAPVAPAVPAVVAAPVAPVVPVAPVAAAPAAVPATFACPMCGRTFTRQKGVWKHVATTHLGTVCQVPGCGHPTGTDARMKAHLKAAHQRSHRVLVAGVDRFQCAWPGCVRTFTRTWDANTCFGKHQADAFAATVVAAPVVAAPVAAGPVAAPAPAQQQQQQQQQQQQQQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WD33</accession>
    <name>A0ABR1WD33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cutinase</fullName>
            <ecNumber evidence="8">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008193</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cutinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667850.1">
        <property type="nucleotide sequence ID" value="XM_066812508.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045568"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043580">
        <property type="entry name" value="CUTINASE_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF13">
        <property type="entry name" value="ACETYLXYLAN ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00155">
        <property type="entry name" value="CUTINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 8" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045003140" description="Cutinase" evidence="8">
        <location>
            <begin position="25"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="259"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="270"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="328" mass="33412" checksum="1E4014C0AADED102" modified="2025-10-08" version="1">MLSSGLTFSGAAAALLSASALAQAAAVVPPTPAGGSQLHARQSTGTGKCTDVHVFLAKGNNEPYPGRQGKLVNAICEGLESCDYEDVVMQNMLPDPYCDSVHEGGTNTVKQVIAYNKKCPDTKLVLSGYSQGSHVLGDSLSGGGGVFFNGCVEKPVEPLDPESPAGKAVAAILTFGDTRHSANQPWNHGSGAKGNGLFPRPGDQLDRLNAFADRYRDYCVDTDSICSGADPKNPGAMAHLTYFDNFTDEAAKWVKEKLGGDVKKGDPSKTTSPVASTDVSSASASASASASSGTALSSLPASTATDSATTGGAAQGAPSRINPTAVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE06</accession>
    <name>A0ABR1WE06_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668165.1">
        <property type="nucleotide sequence ID" value="XM_066812823.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045883"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="210" mass="23019" checksum="9E5ABD1EA55F5863" modified="2025-10-08" version="1">MPRSVSGSPSQSAVEEDEVLSTNATVGSEYGGHFEPSSTSISLGESANSSERRSRSGTPHADHELQDRARSSQARRPLTRALVRQAQLHHSAQDDQQPVSARNDTPKRDDGQFRGLTPPPLPYETRPQKKKRAIQEIIEDNSPREPDRMTREIDDLLKPKQQEQAESSSAVAAVQRRGGNSQSAETSLDLDHTAKRIKKTSSSKGDDGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEL7</accession>
    <name>A0ABR1WEL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial fission process protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial 18 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008356</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668013.1">
        <property type="nucleotide sequence ID" value="XM_066812671.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045731"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019560">
        <property type="entry name" value="Mitochondrial_18_kDa_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001:SF2">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10558">
        <property type="entry name" value="MTP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="35081" checksum="686C8A52F34C3314" modified="2025-10-08" version="1">MSWLWGKGKGPDKPQHAADESPASPQAVAPPSKTTDPRKDATDFDPSRLPERKQLPRGMRRLVDKEDKEENFYDELVDGYVPDSTESNVRYAAYATRLRTIMLSAHRYVAYTSDIGESFRPVAHPWLVRSAYGVSWAYILGDVSYEGYKAYWQNQRKINPAVELSDRAQKATGLTNHSISTPEAAAAAAAALSAPPGEVKPLEDYRTVMVQRGIFQSLASMGLPAFTIHSVVRYSGRAMKNVKNAKLRTYGPIGLGLAVVPALPSLFDKPVEEAVEWLFHTGFSLYGGEQFVGGLPSTGREDALSHKPVSKKPKEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL15</accession>
    <name>A0ABR1WL15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nonribosomal peptide synthetase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005481</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668719.1">
        <property type="nucleotide sequence ID" value="XM_066809796.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042856"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003417">
        <property type="entry name" value="PRK04813.1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045201090" evidence="5">
        <location>
            <begin position="22"/>
            <end position="4742"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1337"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1922"/>
            <end position="1998"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="3025"/>
            <end position="3100"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="3586"/>
            <end position="3659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1898"/>
            <end position="1926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2316"/>
            <end position="2342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="4343"/>
            <end position="4365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="2319"/>
            <end position="2338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="4347"/>
            <end position="4360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="4742" mass="519180" checksum="1FEE350F2C7650FC" modified="2025-10-08" version="1">[encoded data, 4742 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL53</accession>
    <name>A0ABR1WL53_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668736.1">
        <property type="nucleotide sequence ID" value="XM_066809813.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042873"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="15186" checksum="8F826D13C16B7026" modified="2025-10-08" version="1">MTCSSSSYVLVIWLPVIDQTVIPLQLIREAARFTGGPPAKLPRSDGDGTSSSESEEEENSDSEDDGGYLLEAITRLRELSFLSTREPGASASLHAYEMHKLVQEAARYRLEKGKAAYFVQAAFEVVDNLFPDSRREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL90</accession>
    <name>A0ABR1WL90_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">54S ribosomal protein L6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005539</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668777.1">
        <property type="nucleotide sequence ID" value="XM_066809854.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042914"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_uL6_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002358">
        <property type="entry name" value="Ribosomal_uL6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="60S/50S RIBOSOMAL PROTEIN L6/L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL6M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00525">
        <property type="entry name" value="RIBOSOMAL_L6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="5">
        <location>
            <begin position="76"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="5">
        <location>
            <begin position="147"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="244" mass="27029" checksum="0BD2B1F8A6360CB1" modified="2025-10-08" version="1">MLAPSRGRVLEKALNCSKSAAALPSFLIPAFQSATSAQQPPQAGPDAHLDTPGVELSIGEPFVKKDPTTYLRIPKRNVTITGPLGELKLEIPPYLTITQDAESRKAVLSIEDREAKQQMEMWGTTWSYLNRHIMGVSEGHTAILRLVGVGYRASVEDRPAKAAYPGQKFVCLKLGFTHPVEEGVPEGMKASTPQPTRILLEGINREEVMSFAAQLRKWRRPEPYKGKGIFVNDETIKLKQKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM84</accession>
    <name>A0ABR1WM84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669140.1">
        <property type="nucleotide sequence ID" value="XM_066810217.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043277"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="22328" checksum="AA24980B152A93A4" modified="2025-10-08" version="1">MSLPAPTPPLLLTKRLTSFLQANLSPQIHTTLLTTLSGKLLAHASPHPVSTLRTQCTVAASIWTIYAAQGTSTAVAEALPSAPAGTKARQDPTSGAITIQLTGAVLVVRRLRCGLLFVCIGPIPDSGEQVQPAQGQSQSLQVPQAASSSHPTPLGSPSEVESVASVGAATTASVTTMGSANAAGVVLLRRQAEELAKWLDDKLGSLGVPDEEAGNEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WME0</accession>
    <name>A0ABR1WME0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Terpenoid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005972</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669210.1">
        <property type="nucleotide sequence ID" value="XM_066810287.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043347"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="336" mass="38512" checksum="18242A10CB4D2039" modified="2025-10-08" version="1">MEFRYSSLVDPRHYQTHGLANGIPLRQHDDSVKERAGALRAQRDWGKFVFPIQGYNGGLGDRFSLIRVTIPECLPERLEIISYANEFAFLYDGANLCRFIQDAMEEIDLKDNLDGDAVTIPFLETFGAETVLDVTPKVAAQPEKRLQAQILAEMMSIDPIRAITTMEVWGRFVRLASETRARPFGTMTEYVPSRVVDVGELIWFGTLTFAMALTIPEEDLQECMELARPAYAALALTNDLYSWDKERKAAEETDQDYVFNAIWVIMKERSVSEKEAKNICCEEIRKYVQEYCEIVEEVQSEPAHLGKDTRTYLEAIKYTISGNLVWSIYCARYNDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WML1</accession>
    <name>A0ABR1WML1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669260.1">
        <property type="nucleotide sequence ID" value="XM_066810337.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043397"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="184" mass="20094" checksum="4A8B211FA5E1AEBC" modified="2025-10-08" version="1">MLSKILAWFVQQQRETGRTMTRWGGASPDEWYVMFRSAGGGRWWSLVVAWTAGRPGQAKAVSSLAVKRPFAHVARTPMPEAKAGSGTRLFVSGAFSASPLVAAGARSTADSRDCGATPRPSVQNAEESKSGRVTEWASSFCLGSWDPMLQDDQFQQACSQFEPVTFWSPVAVHRSFDVTYPAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMU1</accession>
    <name>A0ABR1WMU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668846.1">
        <property type="nucleotide sequence ID" value="XM_066809923.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042983"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="272" mass="31396" checksum="D96F6A4702A8022E" modified="2025-10-08" version="1">MIIPTTVVVVRRDFSSSSDPAAADGSSSTGGPRNLIIISTVLGSALLLATVLTLLLLWSRKRQRRRAEYREARLRDPTLTWDDYERRRKLRRSMLMWEEEVQRDIILRKTLQSRTSFNTSQSQLRTVRTQTPPSPTATAHTTHTTHTTHTTHTTRTRTRQPKRMRSQSWHPSTVRAGTSSALFPEMTENEHRDGFVQEWRDIEASLDMTWQILTGKRHPSTDDTRRHLLRDSSDEPLARPPTALLKQPSLWAHPAFRGLPKLRNIYKEFIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMZ1</accession>
    <name>A0ABR1WMZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006182</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669420.1">
        <property type="nucleotide sequence ID" value="XM_066810497.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043557"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF57">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="32"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="316"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="372" mass="40836" checksum="217937B3B9389123" modified="2025-10-08" version="1">MVFLFPIERPEPRALFGCAIVFSLVPSLFVALRLIARRKAGRELDASDYLILVALVNVLGYQGLNMACVLVGGAGWHVKELTERFGIESGPTTFIKMMLAQQIVWATSLAFTKISILVLYCRIFTLRMFTIVAWVTSVVILLWVILVVAGSLAICQPAAFNWDQTIPGGHCGDSVKLWLSHGILNIITDMVVLLLPMPVLYQLQMVLYKKVVLMFTFGMGLGVVVISAFRLHSLVEVDMTDVTYTVPLPIMWSALEPCLGITLACVPLLRPLLGGDDKHSSNEERYDMGGVKTIQTIGQKKSRKFDQLRDDDCSITQLTSTTPPPFRSEPLHYTADVVSKDTSGSDDDATDKGEPAVAINVKKGLDSGGRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNL8</accession>
    <name>A0ABR1WNL8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional protein RIB2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669634.1">
        <property type="nucleotide sequence ID" value="XM_066810711.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043771"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18785">
        <property type="entry name" value="Inv-AAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="171" mass="18451" checksum="BD4A2D945A7F651A" modified="2025-10-08" version="1">MADSSLPSLDIAAGDHEAYLRHALSLAQKSPPKPSNYRVGAVLVNAATNEVLSTGYTLELPGNTHAEQCCFEKLAQQHSLSADDVLPDDVALYTTMEPCSFRLSGNLPCVDRILQIGAAKIRTVYVGVYEPEKFVSDNSGRQKLQDAGIAYVHVPGLEKEILEVATAGHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP86</accession>
    <name>A0ABR1WP86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidoligase enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669853.1">
        <property type="nucleotide sequence ID" value="XM_066810930.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043990"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022025">
        <property type="entry name" value="Amidoligase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847:SF1">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12224">
        <property type="entry name" value="Amidoligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="46453" checksum="F75A01A214C5F7BA" modified="2025-10-08" version="1">MAHLDDPIMALEDHQGDLTFGVEIEFLTPVIEISEDDPHPAESRQVLRVSKCDSNNYEWIAELSRFLLNSLQEIPDLAVEGEDGDEYVAPHDNVLKYDHWRLIGDSSVQICTKLGSPASRFPAYHWDGKEVTSEVLSSIDPDRFRKVTEVCRAIRSHRVHLNESTSIHVHVGRGDDGFTLTTIKKIITFLWFADIKLFDLHHPSRLKNLHCRPISEYSKLTEVDHTGIMGVVDPDGLKQMSRHIPEIMSTMNDGVYRNRYIQLKQMWGRDEITEVAKSMLIKKTANNLVQPRGSVGFRRFMPQGKTGGNINTFEFRHMAGSLDPEHILHWAHVCIGIVDFARNTDASVFRAQIAKFLDPPPGYGGAEVLEDIGLAKEAKYFRSKTDSFKSEDFKTCKDGDKDTFFVPPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP94</accession>
    <name>A0ABR1WP94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669811.1">
        <property type="nucleotide sequence ID" value="XM_066810888.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043948"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF3">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="207"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="454"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="542"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="790"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="791"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="810"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="827" mass="91013" checksum="89332ABA037E3C6F" modified="2025-10-08" version="1">MSSHADRDPLAEADHSSQYASASQWRHQESSSFHRHVVPRDAQLASADTQDLSSFLNKSRVEGDRPSTQDTGNFKPIVIGDTNGANDGAADTAAVDDGKEVVCGPLINFRHMENGVWYGSALIVTKGGGKTQEFKPTLNIGRVEAARSLQQGLTGEGVEANGAESALANDANGIRSDHGTDVAGNCLYSDPRNTFWQFPLTCDVHEAETKWAYSIADVRYKSTTKPKVNYFFVPAASESMRMMFHSCNGFSVGTDEDAWSGAALWNDVQRRHAENPFHVMIGGGDQIYNDGIRVDGPLRAWTDIGNPKARRDYPFPESLRQACDDYYLNNYIRWYSTEPFATANGQIPALNIWDDHDIIDGFGSYVNDFMKCDVFRGIGGTAHKYYMLFQHHLAPPSSTYTTDAPQTMEAGDNADHAQLKDTFVAKQTLGTEQGYIIGKQPGPYVAEHSMNMFARLGARVAFVGVDARTERTRHQVNYPETYDMIFDRLRQELSTAEQSGQGYKHLIVLLGIPIAYPRLTWLENIFSSPMIAPIKFLNRRFGFGGGVFNHFDGSVDLLDDLDDHYTARTHKKERNTFIERLQGVAAEHSVRVTILGGDVHLAALGRFYSNPKLHIPAEEDHRYIVNVISSAIVNKPPPNAIANLLARRNKIHHLNHDTDETLMNLFNKDPGDTNKTASSNHVTMPSRNFAIITENSPNNRGATANGDAEAKAAAATGNEFEGKDGHSFLHKGERNAGTDHKASRLETHGKGNDGSLDCCIRVEIDQHNAEGLTQPYGLTIPALSYEAGKYASHKARSIRSHASKAGTARPGTQNTGSAAPSVRRASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPB6</accession>
    <name>A0ABR1WPB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006148</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669386.1">
        <property type="nucleotide sequence ID" value="XM_066810463.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043523"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20546">
        <property type="entry name" value="CYCLIN_SpCG1C_ScCTK2-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="147"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="359"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="362"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="497"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="519"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="528" mass="58718" checksum="2D434891F9CD4DC7" modified="2025-10-08" version="1">MASIDRYRPPAREGYQPPTTTRPQAPQNPQQQQHPQLSSTTAATTNGARSATRSSKSPIKRRDVPPAVPTPPPHVHYPPPAHNSSHPSPTRPRSARSPERTATEPAARRSMAANQWLFTQDEVDSSPSIAEGMPPTEERLRRAKGVNFIYNVGIMLNLPQLTLYVAGVFFHRFYMRCSMDEKRGIHHYNIAATALFLANKTEENGAKTKNIIIAVAKVAQKNANLIIDEQSKEYWRWRDSILSYEEVMLEYLTFDLSITHPYQILYKLLEELNCIHNKDLRKSAWTFCNDSCLSVLPLLVESRDVALSSIFFASIITKQTIPDLGGKPWWIALEGNEERMQQACAIMVDFYKENPLRKAENPSYQGSPGFNFDSTRNTGEGSSTNVSPRTENQTQSPEPRSKGRANGHSNDETAANESAAKSTANGTSSIEANDDAMDIDESSKGGSFANPESQGPPQTGPGDSDTALKEAANDPATHEHTAQDDSRNAEAFSSPAKRKEHEPVSDENRDQKRQRRDSEEDEGEVLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPI4</accession>
    <name>A0ABR1WPI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669966.1">
        <property type="nucleotide sequence ID" value="XM_066811043.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044103"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="177" mass="19957" checksum="A28414CAB1167DE9" modified="2025-10-08" version="1">MNEDLRSLEFTRPWAKGSAGRAWDDAFDNAPPDHVFLPPLFGYMGPTELIWGRASWTLNLVTSRSGPQLDHTDPAGQQHFLELERHLIAEQPHLPVHLRRDDLTSLILPNKCTHDFPIGFHGKQKLLFDLVARIVPVSPQLLLVPRIEEVPARGAGDVVELEQRPSTTTKAEPEREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQF2</accession>
    <name>A0ABR1WQF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA damage-binding protein CMR1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007043</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat DDB2/WDR76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670281.1">
        <property type="nucleotide sequence ID" value="XM_066811358.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044418"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050853">
        <property type="entry name" value="WD_repeat_DNA-damage-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="27"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU365004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="336" mass="36901" checksum="D1DB92C0F6F53DAD" modified="2025-10-08" version="1">MAPELSAFEARRRANVANNAKLLKDTQDAAAKMKKAAKPVPKPAAPRKRKAPAEPAQKTRVMPTRQSARLSGTEPVVDATSIKGEDLSVWESKPKRARTTGDLKLDKMAIEGTRWANGGDTGAFASFAQGAQPGVRTFTDDDIKDTSDEKLKDLRKSMNDLELYDGWQPNDIKLTTERIYAMAFHPIKEKPLIFAGDKKGIVGVFDASQEKPNYDDDDEDADIPLPKVSAFEMHTATISSIITPLCDHNSVISASYDSTIRCLDLPTQVSSQLWQPADDSDDLKITCVDMSPEQKDVLVFSTMYGSLGRIDRRAKAAEADLWNLTDNKIGGFALNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WR31</accession>
    <name>A0ABR1WR31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">U4/U6 small nuclear ribonucleoprotein Prp4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006147</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669385.1">
        <property type="nucleotide sequence ID" value="XM_066810462.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043522"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00500">
        <property type="entry name" value="SFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="4">
        <location>
            <begin position="83"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="308"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="350"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="396"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="504"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="543" mass="59844" checksum="03F5E47DEA5E579E" modified="2025-10-08" version="1">MMHPSRQAYVEEATEVRSALLYCNRLPVANVQSQDRTIALEDLQTDHDYEIPGGDAGIAPEKASAILSKFERKRFANTIAVPTDDGRVRTKLRELGEPMTLFGEDPADRRARLRELLTVQAEQAAAAGGEEGTPDVEMEDADDDADDQEEEFYTQGSEELLKARQDIARYSLPRAKKRLEAQKEESNIVLRTHVKFRKQVRERLQGFELQGSQTAGDRHVSMTRISPNSEMVAAGNWGGSIKLIEIPSLEEKGTLRGHTNKVSGISWFPGATIPERGVSRSSVNLASGGAEGQVNLWSLEKDTPLSTLEGHVQRVCRVEFHPSGRYLASASEDTTWRLWDVETTTELLLQEGHSRGVFAISFNTDGSLLASAGLDSVGRIWDLRSGRTVMILDGHQDGHIKPIHGLDWSSDGHRVLTGSADGWIKCWDVRKVQRTGGIGAHKSAVSDLRWYKGLDDPLEGTVQPGLDDKGNRLPKKSSTFFVSSGFDNKVNIFSADDWSLVQSLNGHTGPVASVDVSRDARWIVSGGHDRTVKLWGRNDGEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRM3</accession>
    <name>A0ABR1WRM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006220</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669458.1">
        <property type="nucleotide sequence ID" value="XM_066810535.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043595"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049680">
        <property type="entry name" value="FLVCR1-2_SLC49-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 49 MEMBER A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="550"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="593" mass="62900" checksum="9E8C8E71E99BDC02" modified="2025-10-08" version="1">MSHSTSRNLGPSSTSTSSSSSSSSPVHRHEPLRENDGVKELSEETTSTHSFSDDGDIKADQTGALGAMGSSSKNHDWSPTLSTATHHRLDSRGGDGDGDGDMKNGGVAQENSQTFYVDDGGNDADAMVATVNDLDGDDGSIRAGVVYRTYKEEVVRIGAIDAAEHYRELGHGKPHIQQEPWNIPFWITFSPVSQLSATYYNVSESAINWLSTGFLFVFVVTSPITIYVLHKGPKLSIVTASVLVLTGNWIRYAGSYSGNGGNFGVVMFGQVLTGAAQTFVLSAPTTYSDLWFTHRGRVGATAIMSLANPFGAALGQLITPFIVVGPRDVSNAVLYVSIIATVISIPSLFTPAAPPTPVAPSGSSPKEPLVASIRRVIRIPEVWMILIPYGVYVGFFNSISTILNQTMMPYGYTSDEAGIAGAVLIVVGLVSSAITSPILDRTKLFLVALKALVPVIALMYLIFIWMPGTHDAAGLAGPYVVLAILGAASFSLVPVALEYLTELSHPCSPEVTSTVAWASGQLLGGIFILISDALKTGSDANPPLHMQRSLIFHAVLALAVVPLVICLGLFGRGEFVELKRASSDKRRSPAVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRU0</accession>
    <name>A0ABR1WRU0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669653.1">
        <property type="nucleotide sequence ID" value="XM_066810730.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043790"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="126" mass="12562" checksum="587087448EDB7B63" modified="2025-10-08" version="1">MPALFDNLKAKFKAIFKKWNDSNTRCPPQKDKKSKAEDKSAEAPEANPAETAATATTAAETAAPEAAVPKTEAAPTAAPAEASAAAPAATPAPAPAPASESAPAEVTPAVPAATAETKAEEKPTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYI5</accession>
    <name>A0ABR1WYI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Small glutamine-rich tetratricopeptide repeat-containing protein 2-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003187</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SGT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671120.1">
        <property type="nucleotide sequence ID" value="XM_066807502.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040562"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047150">
        <property type="entry name" value="SGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032374">
        <property type="entry name" value="SGTA_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831:SF2">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16546">
        <property type="entry name" value="SGTA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="SGTA homodimerisation" evidence="6">
        <location>
            <begin position="7"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="229"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="36553" checksum="A8DE5AF1A1518C82" modified="2025-10-08" version="1">MASTLTSKQRLALAICDFLSTSTEDGTLSADDKDSIDVAVNCIAESFKVDPTSQEAVKEAVGTQNLLKIYSVYEKLQSATKPAAAAAPAGASAGAASAAASKTPSEDDKKKAEELKGQGNRAMASKDYPTAIDFYTQALALHPGNAIFLSNRAAAYSAARDHESARADAEAAVVVDPKYTKAWSRLGLARFALGDAKGSMEAYKQGIEHEGNGGSDAMKKGFETAKKRVEELEQEDPDASAPSTRGGAGGAPDFSSLASMLGGGGGGGMPDLSSIMSNPMFAQMAQNMMSNPDMMSNLMSNPRLREMANQFGSGGGMPDIGALMSDPNIADMAKNFMGGAGGPGAGRGPGSPPPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X033</accession>
    <name>A0ABR1X033_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003755</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671688.1">
        <property type="nucleotide sequence ID" value="XM_066808070.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041130"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000554">
        <property type="entry name" value="Ribosomal_eS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047861">
        <property type="entry name" value="Ribosomal_eS7_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01251">
        <property type="entry name" value="Ribosomal_S7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00948">
        <property type="entry name" value="RIBOSOMAL_S7E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="202" mass="22873" checksum="35C37E22B8765E4F" modified="2025-10-08" version="1">MSASLNKIAPNSPSRQNPSELETSIAGALYDLETNTADLKVALRPLQFVSAREIEVGHGKKAIAIFVPVPLLQGFHRVQQRLTRELEKKFSDRHVLILASRRILPRPKRSARSRNTQTQKRPRSRTLTAVHDAILTDLVYPVEIVGKRLRTKEDGSKVLKVILDEKERGGVDYRLDTYSEVYRRLTGRGVTFEFPQSGAPEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0V8</accession>
    <name>A0ABR1X0V8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome biogenesis protein SLX9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003997</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLX9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671930.1">
        <property type="nucleotide sequence ID" value="XM_066808312.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041372"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028160">
        <property type="entry name" value="Slx9-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15341">
        <property type="entry name" value="SLX9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="214" mass="23611" checksum="90B8834DA6266214" modified="2025-10-08" version="1">MAPTAPTKRRSLRAKLAAKTNGPEPYAPRKAPRPDSAPVSDDFISSKKDKRLVKHSSFVSRIQKANKKPLKRRRPGKKLVTDLDSMKKALPDLLEGGTTEEGLKQLKEGKVRLKSLRSRKGALKRKEKLVKSELERFQGNMAQLNAMRASGQDDVAMEQQATGQDAPSAQEVSQQSQATTGSSNMPTRWAALRGFISSTMEQNPAFLEQEAGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X102</accession>
    <name>A0ABR1X102_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">proteasome endopeptidase complex</fullName>
            <ecNumber evidence="3">3.4.25.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_004051</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671984.1">
        <property type="nucleotide sequence ID" value="XM_066808366.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041426"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03763">
        <property type="entry name" value="proteasome_beta_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024689">
        <property type="entry name" value="Proteasome_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF4">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12465">
        <property type="entry name" value="Pr_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0888">Threonine protease</keyword>
    <feature type="domain" description="Proteasome beta subunit C-terminal" evidence="11">
        <location>
            <begin position="221"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8089090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="269" mass="28935" checksum="CEE92AD7E1B758D2" modified="2025-10-08" version="1">MPGFDFSNYNRNAALHARGVPLPKATSTGTTIVGCIYDGGVVIAADTRATSGPIVADKNCEKLHYIAPQIWCAGAGTAADTEFTTALISSQLELHSLSTGRKPRVVTCMTLLKQHLFRYQGHIGAYLVVAGVDPTGVHLFTVHAHGSTDKLPYVTMGSGSLAAMSVFETQWKPTLTQQDAMKLCSEAIQAGIFNDLGSGSNVDVAVITPDKTTLHRGYVKPNERSQKLKNYKFARGTTAVLNEKIITKDEIGKYVSVQTVEGEQMEVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X198</accession>
    <name>A0ABR1X198_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polarized growth protein rax2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004122</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672055.1">
        <property type="nucleotide sequence ID" value="XM_066808437.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041497"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024982">
        <property type="entry name" value="Rax2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048266">
        <property type="entry name" value="Rax2-like_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048265">
        <property type="entry name" value="Rax2-like_third"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778:SF2">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12768">
        <property type="entry name" value="Rax2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20842">
        <property type="entry name" value="Rax2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20843">
        <property type="entry name" value="Rax2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1142"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="domain" description="Rax2-like second" evidence="4">
        <location>
            <begin position="225"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Rax2-like third" evidence="5">
        <location>
            <begin position="369"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Rax2-like C-terminal" evidence="3">
        <location>
            <begin position="891"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1190"/>
            <end position="1215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1215" mass="128064" checksum="9F315C3AF17763B9" modified="2025-10-08" version="1">MRISYRRRPAARKPANSFTSYLFGLTTIATLSHALTVTPVPSPDLDLSNLGRVAIAGDFAGISLNEFEGQTEQPFNTNGSESLMTRLPNGVFSNILTADASIQTICSFRGALILGGNFTSLDGRSSTGIAQFNLDDMTLSPIAGLLGQVNTLLCDEDAGKVYVGGSFKAADSTNAITWVADSNWASLPFAGFNGPVTSITKASNGHIVFGGRFTGLGNTSTPSQPDEQVINLSTATISANQGTTAAGFRNTWLLADNTPGSWSAKFRYGFQPTKLRLWNTHQDGRGVKTWRYTALPISGIMNFTYVDPKTNQNTSCTSECPLSDDPSVEFQDFHFVNLVGQNEFRIDVSEWYGKGGGLNGIELFQDDIFAYAINDFNEPSCANTSFASSATATGDWKVTPSGASSADYLSVNIPSPVNSAAASITFFPDIREAGNYTLSLYTPGCIPDGTCLTRGQVNVTWSVSPNTPVGSKVLFQTNNFDKYDVLDMAILDASSSSFRPSVTITALNNQDLSSMTMVAQKVNFVLISSTGGLNGLFEYDPSKAKIDTADFKTSAFDKLGSTFSKGSAVSSLATAGDVTYIGGNFTSDKVRNIVAINSKDSSTVQLESGTNGQIMSMALVRDQLFVGGSFNNTSDGSNEALKNVAVYDTASKKWASLGAGVNGPVVNVVDMTLNLTSNKPESVIAVSGSFSQLLAFGNNPERPVNGFAIWVKSQSNWLQNLNGPTPFLDGILSTSFINGDDDGKSVYAGSLSSQVLRAEGAATMGDKLGSFPLNIQPPTPTANTTSNFAGVRRRISPANSTDVSGVVTGAYYKEGGQNVTILAGHFSATDSEGKQIANMAFIDGGANNRVTGLPAGVSDESTIRAVAIQGNTLFAGGRVNGTVGESRVNGLVSFDMASKKFNQQPPSLSGGEGTVSSITVRPDSGDVFVGGSFDDAGSLDCPGLCVFSTSTFQWSRPGFGLQGDVNAMIWSSKTKVVVGGNMTLNDTSAFLASYDASSSSWSGFPELPGPVNAITAANKEGTQLWVSGTGKDGKVYLMKYDGSSMVSAGITFGAETVIKSLQVFTVTETRASDSKLVDSNQILMITGSLSIPNFGKASSALFDGEKIRPYALTGNTGNSAGSIAKIFVENPDNFFKPSNPGLAVGFIVLIGLAISLALMLLIVVAGLALDRYRKKRDGYVPAPTSMYDRGSGMRRIPPHELLDSLSKGRPGAPHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1J1</accession>
    <name>A0ABR1X1J1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methylisocitrate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672155.1">
        <property type="nucleotide sequence ID" value="XM_066808537.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041597"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905:SF2">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13714">
        <property type="entry name" value="PEP_mutase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="33778" checksum="F368D6943C3E0038" modified="2025-10-08" version="1">MSTAKTFNPNTEPRRVYTMVSARVAIEQGFQVMYQSGAMTTAARLGRADLAFASLADFAANAQMIAHLDPRVPLVADADTGFGAPPNIARMVQVYHQSGVAGFHIEDQVANKRCGHLKGKAVVDMERRKKKKTKTRRRPFATGGWGRELAVVVVVITAADLVVFLFAGSRTWKSRIRACVIGRDTIYGGSDIVIIARTDAMAVEGYDAALERLVAARECGADMGFLEAIETEEQIKNAVKVLAPMPLAIYPGQAAKSVLHTIKEAYQCLRETGKDHAEAKGLDPRGFFDIMGLEGEMEIDRLAGGADFSNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1R2</accession>
    <name>A0ABR1X1R2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Leukotriene A-4 hydrolase/aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004230</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672163.1">
        <property type="nucleotide sequence ID" value="XM_066808545.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041605"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="entry name" value="Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049980">
        <property type="entry name" value="LTA4H_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726:SF3">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal" evidence="10">
        <location>
            <begin position="429"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="571" mass="64404" checksum="446E50BBCA9E9E94" modified="2025-10-08" version="1">MAPTRDPNTLSNYGAWLTKHTTVDFKINFDKQRLEGSVSLDLESLTDKESNEIILDTTSLDISSVKLNSADLKWELKQAGHVVKLDIALTTTKDCTGLQWMTPAQTGNKKHPYIPPDVKSTFTFNITSSLPVVASGVPVPSDNSGEGERLFRFEQKVPIPSYLFALASGDLATAPIGKHSVVAAGPEAIKAAQWELEADMDKFLDVAQNLIFDYQWGEYNVLVLPPSFAYGGMENPIFTFATPTIISGDRQNVDVIAHELSHSWSGNLVTSCSWEHFWLNEGWTTYLERRIGAAIHGGPQFDFSAIIGWKALEDTVKLLGEDHEFTKLIISHKGVDPEDAFSTIPYEKGFHFLWYLERLVGRESFDKFIPHYFTTWARKSLDSFEFKATFLDYFNEHGTDEIKQKVAQIPWEEKFYKPGLPPKPEFDTSYVDSCMALAEKWKSSDYKPDLKDIESFNSNQTLVFLQAVQDFSPCLSVERAQLLGSTYNISSSKNVELKTAYYGISLRAGDRDAFPGIVELLGSVGRMKFVRPLYRQLVKLDRALAVETFEKYKDFYPSTTKSQLARDLGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1Y6</accession>
    <name>A0ABR1X1Y6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672312.1">
        <property type="nucleotide sequence ID" value="XM_066808694.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041754"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="711" mass="78872" checksum="0D6DFA2844341874" modified="2025-10-08" version="1">MNWTEGNLARHSRGKTAKNEVLKRQKEHFAKARSRLLNGRSRRSPVTISFLKSPIARQPPIHISSPGHGEPSSPEDQRHSPSKRVGSGIIHGLPPFRNEFEKHHRHDPFVAKPEITRNEPSTRRATTRKAETTLERASSEKRRKLLDRADWAGLSIQQPLELIFPGQMRAGRIWSKPDHAERSTIGKSRNCVRGRPVHREKPLRYKDGDRRLQPAAQRINVQVGSQDTYIGNGSSPLSIRRRLAGSDRGNSTEISTGISESSYRSSCRDDWVRHCRKPSSRSTDENRMEQRNNSRRSASELGWDLEHSSSGSNATRVAYASLTLEQPAPLRAGNFQVLRWSPSVSLNSESLEVEVGQPTSRPDAMDIAENEKWRTLVDSSDHLIPLTRGSSLFNSPHMNPAPIPIISEMVAESDEASTGLTSGGHIQDDEGRPSRKSHPVMAARAVTNDRDSGTPTAQLPRTPAASLVRNKPRDSKVRNDIDENMAWMKFVFDSDDDEFERCAMQEAARLAAREIRPSKSPEINSSEASSEYFQSIRHRADSPHVPLDVSLGSSDDVASTAVTGASRMATHGSVYSSPSATNERSETSTTCNNFDDLTRGGFPSPDCNASAKSATVSDAETAKATMATSEASETSRDTQQRHRFTAPQAFVGRHAQPDKSRYMQMPPPGLPDITKSSKRKGRRKKKALDGRTSIRELANFDGDPIEDIEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1Z7</accession>
    <name>A0ABR1X1Z7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosomal RNA-processing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004388</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672321.1">
        <property type="nucleotide sequence ID" value="XM_066808703.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041763"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06185">
        <property type="entry name" value="PDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.20">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052353">
        <property type="entry name" value="Benzoxazolinone_Detox_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005163">
        <property type="entry name" value="Tri_helical_YiiM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30212">
        <property type="entry name" value="PROTEIN YIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30212:SF2">
        <property type="entry name" value="PROTEIN YIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03475">
        <property type="entry name" value="YiiM_3-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00409">
        <property type="entry name" value="PHDIOXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="5">
        <location>
            <begin position="39"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="248"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="4">
        <location>
            <begin position="471"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="554" mass="61501" checksum="945C9A94EE850D78" modified="2025-10-08" version="1">MAPAADIDLYAPFEKDVILEVRSSKMKTMPGLSVLSGIDKLVRQGRVPVSMIGLDDDEHDLVFHGGPDKAILGYCSSHYPDWQAEYPEAASRFQPGGFGENFVTRYMNERNVCVGDIIQVGEPGVGPLLQVSLPRQPCFKLNHRFQLKNFAPKVYSTSRTGWYYRVLKEGTVAAGDEIRLVERRWPKWTVERVQEYLHRKQDDHAMNEELAGVEDMGMESRGNFQNRVAKQKAREKKAAAGADPGPAEKWRDYKIAEKRRQTDRIASFTLEAVEKDPEAEDSRLGSHARLKLPNGLIRSYSVVSGNPNRFELGIALEEASRGGSKFMHSTTEGDVVQVGRITSDVQPKGSASQHVFIAGGIGITAFLAMMDTYRQIHWQTVLHYAVRSESDIPFRETLDLLGDSAKLYDASKGQRMDVPAILGNLGWNSYVYVCGPRRMMDEALRVSKEAGLTEADIHFEAFAADTTGDPFEVEVANRGGKKLQVGEEETLLEVLKKNFDDIASSCEVGNCGTCKVGLKGGKVEHRGTALMEDEKKDSMLSCVSRGMGKIVIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2V2</accession>
    <name>A0ABR1X2V2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anp1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004687</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672620.1">
        <property type="nucleotide sequence ID" value="XM_066809002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042062"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF6">
        <property type="entry name" value="MANNAN POLYMERASE COMPLEXES SUBUNIT MNN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="362" mass="41084" checksum="2E21C6BEDCF58E9C" modified="2025-10-08" version="1">MARPMGPVRLRRTNPVTVIIGIVLCTFIIYFLSNSGSATRPTTSKSRNANSKPVPKSNLAHIRRDVQRFNLNHVTITKDPIANHEAVLILTPMARFYQDYWDNLLKLSYPHELITLGFIIPKNKEGNAATTALQAQIAKTQKSATNKFRRVIIERQDFDPPLASQDESERHKMENQKVRRAAMSKARNSLLFTTLGPDTSWVLWLDGDIVETPPTLIQDLASHDKPIIVPNCYQRYKDDSGKMAERAYDFNSWQDSETAQELAAKMGPEDLLLEGYEALPTYRTLMAYMELDEKDDVRAEVPLDGVGGTALLVRADVHRDGAMFPPFPFYHLIETEGFAKMAKRLGWQATGLPNYKVYHYNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3B8</accession>
    <name>A0ABR1X3B8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Cellulase</fullName>
            <ecNumber evidence="3 9">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_004836</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 45 (cellulase K) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3 9"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672769.1">
        <property type="nucleotide sequence ID" value="XM_066809151.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042211"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052288">
        <property type="entry name" value="GH45_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000334">
        <property type="entry name" value="Glyco_hydro_45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730:SF1">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02015">
        <property type="entry name" value="Glyco_hydro_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01140">
        <property type="entry name" value="GLYCOSYL_HYDROL_F45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046698578" description="Cellulase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolases family 45 active site" evidence="12">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="78"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS01140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8089875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="230" mass="23796" checksum="628DB224C3E09A58" modified="2025-10-08" version="1">MHAPTLLAVLGAASTATALSGSGRSTRYWDCCKTSCAWSGKAAVSQPVTTCDNNNSPISNANAPSGCDGGSAFACANNSPGPSATTSPTASPPPPSPPSRPPAAPASKITFTSGPVSGKTMVVQSTNTGGDLGSNQFDLMMPGGGVGLFDGCTRQYGQALPGQQYGGISSRSECAQFPAQLRAGCEWRFDWFQNADNPNFNFEQVQCPSELVARSNCRRNDDASFPAFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3F7</accession>
    <name>A0ABR1X3F7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004843</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672776.1">
        <property type="nucleotide sequence ID" value="XM_066809158.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042218"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF1">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="50"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="273" mass="30314" checksum="CCD269DDFDD00816" modified="2025-10-08" version="1">MANTEGSAPAHYDSFATSYDEIWRVPGIRPLLPLLTSTLESVGPHKDIAVLDLACGTGIGLRVMQALGARRFVGVDISTQMLELYAADCARPLAETVPALKDEQGRFDVVLGMWLLNYAPSAAELVGMWANVAAYLKPGGRFVGTMENHEAVTAPRLQSGKYGVTETELNPLPGGHAEDGFQVHLRFQTEPVVEFDAFRMKKDVFEREAAKAGMINLQYKRPGLDEVKKMIAEGIGAPRRRTRRGGRSCLTRRPTWWSWRRSKVSRRRGFPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X402</accession>
    <name>A0ABR1X402_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Hydroxyethylthiazole kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_005094</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>4-methyl-5-(2-phosphooxyethyl)-thiazole + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H(+) = thiamine phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17957"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673027.1">
        <property type="nucleotide sequence ID" value="XM_066809409.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042469"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01170">
        <property type="entry name" value="THZ_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00228">
        <property type="entry name" value="Thz_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000417">
        <property type="entry name" value="Hyethyz_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006830">
        <property type="entry name" value="PRK09355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857:SF23">
        <property type="entry name" value="THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857">
        <property type="entry name" value="THIAMINE-PHOSPHATE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02110">
        <property type="entry name" value="HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01099">
        <property type="entry name" value="HYETHTZKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="Thiamin phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamine phosphate synthase/TenI" evidence="15">
        <location>
            <begin position="10"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8090133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="523" mass="55498" checksum="0DF7AFDDE9D8B327" modified="2025-10-08" version="1">MRKQDVDYSLYLVTDSTPAILGTKDICQLVEAALKGGVTCVQFRDKKSETGALIETARKLHAITKKYHVPLLINDRVDVALAVECEGVHIGQDDMTLATARKSLGPDAIIGVTVSTIEELDTACRGGADYVGIGTVFATPTKDDTKHIIGIEGVQRMLFYLSSSRSKVKSVCIGGINAANASQVMWQSMAKQKTLDGVAVVSAIVAAEDPEAAAKDLTRLIKTPPAFAANVKAEEQYRSAEILELVPGIIKAVHKKKPLSHNMTNLVVQNMAANVALNVGASPIMANYAEEANDLAALGGALVVNMGTVTPEGLENYLKALKAYNDAGQPVVYDPVGAGATEVRRSATKRILGAGYIDVIKGNQSEIVSCTPDGAKLQQRGVDSGPTGTDYDVAKLSGVVRDLATLRKNVVVMTGTTDYVSNGKTVYAVGNGHEYLGMVTGTGCCLGTTISAMVAAYPRDKLAATIAGLLYYEIAAELAAERDDVQGPGTFVPAFLDELYRIRMATVQGDLAWLKRANLWVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7I8</accession>
    <name>A0ABR1X7I8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tbc1 domain family member 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001838</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673449.1">
        <property type="nucleotide sequence ID" value="XM_066806153.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039213"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053949">
        <property type="entry name" value="SBE2/SBE22_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF15">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 12 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22874">
        <property type="entry name" value="SBE2_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="481"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="323"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="745" mass="82117" checksum="1A4B6512E68C24B8" modified="2025-10-08" version="1">MNYETDNTVSGAIDLCVPSPGSPPGMISSKTSRASSLRSSIGSDDDNHQVVDVGNFEEIGLEDDTVTVDAAHSRDLTQSKNSPNPYSASYAADLRSRSTKHVGTTGTTVRQQPAQPNPARPQRDITSAGKGRPPFLNFRGQQFRDTSTHNLSGLGAQPHSGPAPIRGLLVRSSSTASASRRQQRSPSPNLSLRTTNPRNPSVGPLPRRRSWQSAHAQEPKKTSLELEREFDEQDDDDHVPEGFILDNVPISPRPMEDRTPSRPVSTSTSPERSKSRVRSVGNGTPLVPAEQGSLRSPSWRSDASSAESIKSPGSCPSPLKGRAKSWNAALSELSAEARSLTEKLEEHAAELDKHGVNSVARPAPKPRVKSALAELPPLRRTNIMIDPLPISKEKEAVLSRTRPSWLPPKDPAEEKKHIKEYQRMMVKSIEADKRRTAAKLEKEKNKDDMSGNTLRIWEEDVLPRWKEALRERRTRELWWKGVAPRSRGAVWTRAIGNELGLTETSFHAALARAHEMEQRIAEGKATTEDERRNSWFSKVRRDVKDNTWVDLKIFQAGGPLHDSLVDVLKAYAMYRSDIGYVSGMNTIAATLLLNLPSATASFIALANMLNRPLPLSFIACDNGAKHSAYNLLLDTLSKKSSRLHAHLTSEELSLDPELYLAELFSAMFTQHLSLDDCSRLWDVYVFEGDSALVRAGVALLLENEGRLLAAKTQKEVLAVCSAGHAKTLQGRGDDWMLRVRSAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8G4</accession>
    <name>A0ABR1X8G4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002086</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673697.1">
        <property type="nucleotide sequence ID" value="XM_066806401.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039461"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="298" mass="34757" checksum="8E925FC3F0D7E6E6" modified="2025-10-08" version="1">MDDDDDTIQLPKGMPRQSGQSYLELLVNTDFTDVQDLFFAHAVRKHYDYQELILYEHTVEAEKPGKKQKEGFVNRYFVVMDHNAKTHLGSSYRPSDDKAESNADIDLDKPKQLFESMVMELEVPNLPMKKARSSKRRSSDQTPTIPRFVIEIGEIKVETWRPGSDGKFEIDEARHIGCHMVMDVETPFNERALWMVHRYRGVEDGVHLKKQRKWDRDDDLFTFLGFKEWDNVWGTIPVDFDLAKLAARAEDWYHRGRDCAPIENMPELMRNTAIRGGCRLHTPMGLFEEFEAKVNKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8Z6</accession>
    <name>A0ABR1X8Z6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Guanine nucleotide-exchange factor SEC12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_002348</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Golgi apparatus membrane</location>
            <topology evidence="10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the WD repeat SEC12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673959.1">
        <property type="nucleotide sequence ID" value="XM_066806663.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039723"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045260">
        <property type="entry name" value="Sec12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284:SF0">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <keyword evidence="2 10" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU369019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8091987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="600" mass="64456" checksum="E1D172FDF6788B9B" modified="2025-10-08" version="1">MANSIPSTTITLSYPLWACAFDPHHPDQLLVGGGGGPGRNGVTNKLTLLDASSTPNEITKTAELELSAQEDNVASLAFGPRRAKSTVVYAGVNGSPDDVKRGNNQHFRVLGISPSNGKAAGTSGVQIADNSRHSLFSSTDPDTYQRLLRVTQPYTGLPQLGALATGLSKQSQIVLFDVPLNGAAWKPRGTLDTPDEAMDLDVVQTGTDTYQLAYCDKHEIFTVEVSPDGVSDPKLVYSLPHDDGPTSRPSFRSIRYLNSDFVFAVVNNANRKGVILHGYRLPKPDQESARLAVVRKLPKTVTASTGLAVRNLSPAASPTEAHGDSQFVVAVAGHDSSISLLTLDYKTISNVDLLANLAPFYTVKSAHPAGITGLSFSTPPPAPKRSKSESDVSIKLASVSMANTAVVHNIPLKKLINKSTSSDTAASEQARYVVALKSLRDRKGWWLLFGTLLMFTTLVCVGLAIIEAKGFGEPVLGTNRLLPASWTVPLKKGPVVGSKTFGDLLTDVKPEAHEKVIIRHDDLGAVDVHGLPVWKVEIHEEEMHGPAKSWEELDEKDRHVWRERLQKTGHWVENMGETVLKGVVFGEIGGAIGAMVGEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X922</accession>
    <name>A0ABR1X922_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_002321</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673932.1">
        <property type="nucleotide sequence ID" value="XM_066806636.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039696"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF24">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="302"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8091960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="596" mass="66960" checksum="30BDEA2ECF62F26F" modified="2025-10-08" version="1">MSNATNSTGAPPTAQKGTAVAAGSGQAKGWTPGMENDALSHYLIFICAAVSGAFIIWKIWTELTKYVRTVTGLTNDTQYYFAKASGKVSWFKKNILYSPMFRKRHNREFQLSSAANMGTLPTRFQFLFLLAYLSTNVAFCVIDIPFDGDYTSAGKQLRNRSGTLAVVNMIPLFVMAGRNNPLITWLGFSFDTFNLMHRWFGRIVALEAVTHTMAFLAVSAHAKDWSQAFDSIWSTPFILYGFIATCAFVAIFIQAASVSRHAFYETFKIMHILLAIISIVGLWYHLDIYKYPQIKWLIPVIPIWIADRFARFCRIAYSNFGRGGTKALVEALPGNACRVTVTMARPWTFKAGQHAYLYMPSISLWQSHPFSIAWSEEAEDLSDEKLAMNRQDILALRKTSHSYVIRARTGMTQNLYERAAAAPDGRLWTTCYAEGPYGGLHMMHSYGTAMLFAGGVGITHQVPHVRDLVAGYANGTVATRKIVLVWIIQSPEHLEWIRPWMTEILAMDKRRECLRIMLFVSRPRSTKEIHSPSSTVQMFPGRPNIETLLSIEMENQVGAMGVSTCGPGALSDEVRAAVRKRQYHGTIDFVDEAFTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9F7</accession>
    <name>A0ABR1X9F7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002374</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673985.1">
        <property type="nucleotide sequence ID" value="XM_066806689.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039749"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8092013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="504" mass="57625" checksum="F5F301B9E632617A" modified="2025-10-08" version="1">MSVLDTGAVALAAYGAGLMLLYSVALAIYRVTLHPLAKFPGPKLAATTEWYEFYHDIVRQGQFIWHIQKLHDQYGPIVRIMPNELHIRDPDYYDEIYAPSSKKRDKSEAWVRSTHEFLMRSNTTSGFATVDHHLHRLRRAPLNPFFSKKSITDKESQIRDKVEHLCRRLAAAAAKTGDEGVVRLDVAFTALTMDIITDFAFGERTRHLDEPDFGLLWKETLVAQSANAVFLRQFPWLWPVLQRTPLRLLRLLQHPAAGLVVWRDLTRERIGRIIAANAAGKRAEGSIFQTVLDSDLPAAEKSAERLEAEAQIVLGAGTETTAKSLAMVAFYLNEDKAKLRRLRGRLRGRGRRRMGHRLHHGRRPHDVRRHRPPPRVAREPLQYRDWSIPPGTPVSQMNYVVNNDPDLFPRPLEFHPERWVDAPERADGRRLERYMVSFMRGSRSCIGINLAWAELYLALAHVVARFDLPPYDTTAERDLVIDRDLFVGVPKPESKGIRAKVVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9T6</accession>
    <name>A0ABR1X9T6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine protease</fullName>
            <ecNumber evidence="6">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000048</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674136.1">
        <property type="nucleotide sequence ID" value="XM_066804363.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037423"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050966">
        <property type="entry name" value="Glutamyl_endopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008256">
        <property type="entry name" value="Peptidase_S1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462:SF8">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00839">
        <property type="entry name" value="V8PROTEASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="71"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="207"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8093363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="247" mass="26799" checksum="76C6C1C137599269" modified="2025-10-08" version="1">MSRFTTLSEADDQIWAAIAPPEAVAFNQADLRTLHNITSAPGSEGDGSVPVSSLQERWAIGNDDRKLWTNREYPYSAMGKVTRPGSWCSASLIGPRLVATARHCYEAGVPYRFNPAYDNGETLPGANAVYVLIPSGMPDEGPCNEKEDWVLFVLDTNLGNQLGYLGAKTYDAASQAGRPIFFNYGYPQDKDGGNRPYRMEGISVTRKEPRCDATGPLDTDVDASPGNSGGPLWALEDGGALPVRRHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9V1</accession>
    <name>A0ABR1X9V1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aspartate aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000128</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674216.1">
        <property type="nucleotide sequence ID" value="XM_066804443.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037503"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF22">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="9">
        <location>
            <begin position="66"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8093443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="400" mass="43522" checksum="F055558738345C5B" modified="2025-10-08" version="1">MLSTLRVATRGAAVARRASAFRFQAVRAGSTWANVPQGPPLASTRHKLTAAAIGITEAFKADSFDKKINLGVGAYRDDKGKPYVLPSVRAAEQKVVSNNLNKEYAGITGVPEFTKSAASISGTGALRIGAAFLERFYPGAKKIYIPNPSWANHGAVFKDAGLEVEKYRYYNKDTIGLDFEGMVADLKAAPKGSIFLFHACAHNPTGVDPTPEQWKEISSVVKSAGHYAFFDMAYQGFASGDTNKDAFAVRHFVAEGHNICLAQSFAKNMGLYGERVGAFSIVAENAEEKKRIDSQVKILILNDPALYKQWLAEVKEMADRIITMRALLKDNLEKLGSKHDWSHITSQIGMFAYTGLTPAQMDSLAKEHSVYATKDGRISVAGITSENVGRLAEAIYKVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAA8</accession>
    <name>A0ABR1XAA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DNA 5'-3' helicase</fullName>
            <ecNumber evidence="17">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">PG997_000295</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the helicase family. RAD3/XPD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="17"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674383.1">
        <property type="nucleotide sequence ID" value="XM_066804610.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037670"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010643">
        <property type="entry name" value="HBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001945">
        <property type="entry name" value="RAD3/XPD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06777">
        <property type="entry name" value="HBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00852">
        <property type="entry name" value="XRODRMPGMNTD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 22" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="21">
        <location>
            <begin position="7"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="775"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="255"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="743"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="779"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK8093610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="796" mass="91377" checksum="A31B12BF4C4D001A" modified="2025-10-08" version="1">MKFFIDELPVLFPYPRVYPEQYAYMCDLKKTLDKGGNCVLEMPSGTGKTVSLLSLIIAYQQNQPEDRKLIYCSRTMSEIEKALAELQALMKYRADELGYVEEFRGLGLTSRKNLCLHPSVKREKSGAVVDAKCRSLTAGFVKEKKEKGENVDLCIYHDNLDLLEPHNLIPNGVWTLDDLLVYGEKHKQCPYFTARRMMQYCNVIIYSYHYLLDPKIAERVSKEFSKDCIVVFDEAHNIDNVCIESLSTDITDDSLRKATRGAQNLERKINDMKETDREQLENEYQKLVEGLRDQDEARQEQTFMANPVLPDDLLKEAVPGNIRRAEHFVAFLKRFIEYLKTRMKVRQVISETPPAFLSHLKEHTFIEKKPLRFCAERLTSLVRTLELTNIEDYQPLQEVATFATLVATYEKGFLLILEPFESDTAEVPNPVLHFTCLDAAIAIKPVFDRFSSVIITSGTISPLEMYPKMLGFNAHVQESYTMTLARRSFLPMIVTRGSDQAPVSTGFQVRNEPSVVRNYGNLLTEFAKATPDGMVVFFPSYLYMESIISMWQGMGILDQVWKYKLILVETPDAQETSLALETYRTACCNGRGAVLLCVARGKVSEGIDFDHQYGRTVLCIGVPFQYTESRILKARLEFMRETYRIRENDFLSFDAMRHAAQCLGRVLRGKDDYGIMVLADRRFQKKRAQLPKWINEAMQEVDGNLSTDMAVITAKRFLREMAQPFRAKDQDGVSVWSIEDLRAHQAQQDEERIRELRDEAKSAEALAKKMAERAAQNDYDIDEDEEAEMMEIDGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAA9</accession>
    <name>A0ABR1XAA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674424.1">
        <property type="nucleotide sequence ID" value="XM_066804651.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037711"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="78" mass="8534" checksum="172B7AF9313167F7" modified="2025-10-08" version="1">MEAQSVYSDAGKEAHVEHGLNKRRPGQGGIEAAAFPKKHTTQPARKWYTAISNSNERIGMWARSPTTAAVNKVVKRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAG3</accession>
    <name>A0ABR1XAG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674443.1">
        <property type="nucleotide sequence ID" value="XM_066804670.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037730"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="248" mass="26924" checksum="1E38DD3CEAC495CC" modified="2025-10-08" version="1">MIREMTKYHQQLKAERYCNRNFTPDPALQTVHGFAVDHQKLAGAGLSGATNHRAASERTTTSAASGSTEDPTSELTTTYVSACVHINQAAMQQNRAINTASTNQAEPLTAPPHVTFAGVVVPAPPQPQPQPKKQQQKKKVRSPPQAPPLPPPPQQPTARTPTPPPAGIDIYPTSPEGSWIKSYRCVRNPDYDEGDSCESTCTDVTAWCESDKRFVPCMRGPNGRPNGSEGESISEFDLEEVRKGSSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAY3</accession>
    <name>A0ABR1XAY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biogenesis of lysosome-related organelles complex 1 subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000422</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BLOC1S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674510.1">
        <property type="nucleotide sequence ID" value="XM_066804737.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037797"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009395">
        <property type="entry name" value="BLOC1S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13073:SF0">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13073">
        <property type="entry name" value="BLOC-1 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06320">
        <property type="entry name" value="GCN5L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="365"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="243"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="23"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="100"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="429"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8093737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="467" mass="47059" checksum="4B481673FEBC9999" modified="2025-10-08" version="1">MSTSAAAAAAAGPSSTPAPPGPKSAAGVTTSVSAATAFGSKPITMPPSSSTPSGAAAGPENNAASAPAASSSYTHAAASSPLSPLSPRTSVAQAKATTVTASGTTSIPSPSSTTAGILPSPALSSPSFPSYATSSSSRAAGPSGTAAGMSQQQQQTPRSHTGPPPATAPAKPPALEYLELEHLPARPPPTPVPTCPLTRPPPSTTTTLHMTEARDALVATMSNLFDAELQSRASLLHSNATQLSRQESDVAKATEALRKENDKLAKVARDAGRRIKETGNVQNWAEVLERDFLVLEETLRGTGRGAAVAAKVAGKKASTTKSLDEGGLVGAVNDMDIDDAVGADAGVGPSATGKTVEEVVVQDAGDRAGEDNNKPLATMDVDVNDTSGTPPATVPGPSGKYAGEDHEMEGNDGPFSHVDNAIEASIRGGHGDQHARRPEGSGGALRDDARGRLDVERAQEGQGDSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBJ1</accession>
    <name>A0ABR1XBJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">JmjC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674731.1">
        <property type="nucleotide sequence ID" value="XM_066804958.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038018"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="169"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="690"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="998"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1070"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1099"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1142"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1152"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1174"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1196"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1243"/>
            <end position="1259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1286" mass="143768" checksum="1AFF9E5871DC4EE6" modified="2025-10-08" version="1">MPTALHPQAKFDPIPPDLDLHAIVDRNPNFDWVVRINLAQIRRLGPSGFEKLVQLHVIEGGRPLVIEGWNKVLPQSLFSAKWLEKTQDKKQENVRDINSQSDIPMTTGHYLRSLRQLTNQWSPTNFRDERRQRLYMKDIDCPQEWYDHLRKVIPPNVFYMNDNVSDTVGTDSREDDIFGAPEVSAAVAGDLMSSLPEEMRAQNLMCYIGHEGTYTPAHREMCASLGQNIMVDASGSENGEKPGSSIWFMTETKDREVVREYFLSMLGHDIEIEKHFAQVNAWKKAPFPVYIVEQKVGDFILVPPLAPHQVWNRGTRTMKVAWNRTTVETLELALQEALPKARLVCRDEQYKNKAIIYFTLEKYYKELQSLEDTSEVGVLGLGRELTRNSPRLRQMANDFRRLFGLFTGILVDEMFGPKHIDVEYVEFDSNITCSYCRSNIFNRFLTCKCCVRQLINGDEDTYDICMECYVMGRSCVCISGLQWCEQWHWSDLVEKHELWRSMVIKQDGFVDIEYSPQPLEIARRKSSKKSVAQVCQEQLRRRPWSDITKPVIEAAPEPESEPEPEVDEEGRVKKKPKSKRKQKRGDVYRCHVCCHKDYTYKLNFCTTCQEAYCYGVLWRAFDTMPQSAMEKSTGSAPNVSGFATAGVADALGINTLLGHDTRRIADDRSVESTVDFRIHNLNWLKAFGEESRSKDTKRMQRLRQQADAEKAKGPLAALDSNEDAPHEMDSSNQGPTMENADGDHVGVDGAPAVQNGTPGHQDEHAGSRVPTADMSSMDLASFAYPDPAGYNDPAVGARMMGMGFYDQDDSADKILFDPFQIPSEDTLNREPEVSDFVKKTLRLAKRKARLETDDDPDFMGPRTYRKKPRTGNIDQLMNLDPALLGALGEPDRSASGTPIRGHTESEQTPALPEASSSQHENPRPKPTRAPLPVDPLRPTLRHAKPAQSYADHEEPEDDPDDIVMPKRLFNPDAENGDATNGDPVDVAAQAFRAVARLQEAGSTIATPPYTGKRRGRPPRSSLPANAPQATPKEPEKEVAKEPKKRGRPSRRSQLASVDYAEDSPPAQESVNEDEVTEEVLEAVLEAELAREWPRKGGNSKRPPSWKKGPPPKSAAKASPAPAAAPEPTSQPKLMSMAERMAAKGKKFKMRGSSRSMTSNRTTTPSTPQSATARETSDQDTTMKDADAPISRTSSVRRTEEPQSGKSRESSTKPPPAPSAAAPAKAVTRPGPTVVRLASMAGSDSEETDSSFGDDDEEDIPAQKFVAYRGGMRGRGRGGRFATASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBP7</accession>
    <name>A0ABR1XBP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentatricopeptide repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674839.1">
        <property type="nucleotide sequence ID" value="XM_066805066.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038126"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="839" mass="94501" checksum="05AE65A4D82275CA" modified="2025-10-08" version="1">MHALWSRAAQAQSSCRCRGCLHTATTITRRATTAASRRRVTAADIFTACYTTILGTAAVVDAHRKEDRKRDLDEKIDRARAALGNLAIQGAPNRNEARDSSSDNPGSLETPVGTSQWEAGIPSTSVTSLLQELGDLAANTYRGTTRSWRQHQVDWAAVEAAILAEEQDLDIEIRHPYTEAQMGRTTQTIETLVRQLLWRCRESKDQNTQNTQADEAQTHESIIEEVEKLRSGPYYPSYDNPRSDLGGAAEERALLNNSFRRIFDKTADAKEVVGKICYNLLLSSTPPNIHNYNALIAGFNRIQRPDLAQAVVDSYLTDTKWPATQQTMVCLLNHAVTTNNIEQFRIVVRRMRGVAEDGLHFRIVSKNAIFNSQGLLWAEANCASRKHAWVERAKRGNDVFDNLIKGWLHFGKVDVACMSFVACLREGRFVPVDTIQGLLTECHSTLDQGSARQLLKGLGKNFENFESLMKTIHTSSPSEIIRPIFEMFYSLFDLSGLPQLPIIGGVKKSLRAILRKFKSLQIVTEAKIEFDEIESTSRETMRSLGTGNPYSGRVSRALATLTEKPTEKPHRSQTDVMPTKAFGGIPDLAALLKRCENLEAKTLRIEAHVKVLIIYARTGVHCDPQSRLPPIDWQNRQPYERYPAVFHALRRIKTRHLSSELNLRRQFLRGLPDQKLAKQLKDLDLWQKLGFATLMSLYQDGPNASERVRTRQEQTSPDIDGIEGQLEDVEGATRAILFSFLDRRDQHRFRKVYPNWYEMPLAKLYEYHHHDIDELKRPSSGRLVVEMEKDEANVTTVAGSPEMAAVLGSEPEQLPSASGGWPCTSPPACLCTLRDRRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBP8</accession>
    <name>A0ABR1XBP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674893.1">
        <property type="nucleotide sequence ID" value="XM_066805120.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038180"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="33160" checksum="D28B0B2DBB6B905B" modified="2025-10-08" version="1">MRNPKAALPTYNEPRRVVVPLCGGGELGQDLAVRDDGDEVDAGEQVAAPAGDGGLARGVEAVEHLVDEQITGAVGAAALAHEDEGEEEGEVDAFALAAAALGVREGRGDTERGAVEQARGGDTTLLLLLIVFLLLLFVIAVVVRRGISGGGAPRALLVVVIESGGEYDLRRQGVNLAEALLEHVCAEAYRRRRPRRRGGRRFCPPLGEGRVPERKELARLGQLLGHRAQCRILSRQIVARSQLGREPLAVNGGHLPLTLLALLQLLKHRPVHHIGLCMRGFLLPFPLNLLVSLSLVFGLFLNPFRLLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBW3</accession>
    <name>A0ABR1XBW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="2 10">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_000875</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + [thioredoxin]-disulfide + H2O = a ribonucleoside 5'-diphosphate + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="2 10"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674963.1">
        <property type="nucleotide sequence ID" value="XM_066805190.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038250"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01679">
        <property type="entry name" value="RNR_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573:SF6">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51998">
        <property type="entry name" value="PFL-like glycyl radical enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="R1 subunit of ribonucleotide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0215">Deoxyribonucleotide synthesis</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="12">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="771"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="868"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8094190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="906" mass="101024" checksum="4F6DD6F856F27690" modified="2025-10-08" version="1">MYVKKRDGRQERVQFDKITARVSRLCYGLDADHVDPVAITQKVISGVYGGVTTAQLDDLAAETAAYMTVTHPDYAILAARIAVSNLHKQTKKQWSSVVSDLYHYVNPRNNTASPMIAKETYECVMKHKEELDSAIVYDRDFNYQYFGFKTLERSYLLKLNGKIAERPQHMIMRVAVGIWGDDVEKVIETYNLMSSKFFTHASPTLFNAGTPQAQLSSCFLVDMKDDSIEGIYDTLKTCAMISKMAGGIGLNVHRIRATGSYIAGTNGTSNGIVPMLRVFNNTARYVDQGGNKRPGAFAIYLEPWHSDVFEFLDLRKNHGKEEIRARDLFLALWIPDLFMKRVEKNGEWTLMCPNECPGLADVYGDEFEALYEKYEAEGKGRKTVKAQKLWYAILEAQTETGNPFMLYKDHCNRKSNQKNLGTIRSSNLCTEIIEYSAPDEVAVCNLASLALPAFVDYSSGTYDFQKLHEVTQVVVRNLNKIIDVNYYPVIEARNSNMRHRPIGLGVQGLADAFLALRMPFESPEAKQLNKQIFETIYHAALTASMKIAQVEGTYSTYEGSPVSQGILQYDMWNVTPSDLWDWTSLKEQIKQHGVRNSLLMAPMPTASTSQILGNNECFEPYTSNIYSRRVLAGEFQVVNPWLLKDLVDMGLWSDNMKNRIIAEGGSIQNIPNIPAEVKALYKTVWEISQRTVVQMAADRGAFIDQSQSLNIHMRDPTMGKITSMHFAGWKLGLKTGMYYLRTQAAAAPIQFTVDQEQLKVEDSQVSRIGALKKRAPPSGSYVSHPSSPAAGPRPMANNSLASGPGGMSTPSTTPPPAAQVQQPAPSPIKTVPFKADVEEGESPKALPTEPAEKVKDESEPVLQGKKTPGQEEDKGDESKEREFDIYNEAVLACSIENPESCVMCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC19</accession>
    <name>A0ABR1XC19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nulp1-pending protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674917.1">
        <property type="nucleotide sequence ID" value="XM_066805144.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038204"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006994">
        <property type="entry name" value="TCF25/Rqc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684">
        <property type="entry name" value="NULP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684:SF0">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04910">
        <property type="entry name" value="Tcf25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="708" mass="79393" checksum="C3C4A94FA0828F6F" modified="2025-10-08" version="1">MSSRQLRKLQKQKELEQLQARTQEQDSASESDEAPVQKSKPSVFSGFAALGGADEDDSDNSDNKEDIAPDEEPEVVEAIKPASKKTAPRNKATDDADEIDRALRELNLVAKSSKDGSVPGPTTAAAAKPYERICELLSLNTVHLRAINEMRTLFGREAMAAAEMEEQEDEQNRNRRRNQRQMRENVDLETFLRGIPGRSLPEVTLRRNPFLPGKETWPRAATDGLTMKPVKDGTIETKCGTVEFSYAHDQNYNNLERQFFALAQMYEPMQLVHFLHRHPYHVSSLIQVSKIAKQDQNSSLAADLCERALFTLGRVSISTFRQKLVEGKARLDFRRPENRQFWLAGYHYLKSLVMKGTYRTALEWTKLILSMDLADPYGVIHFLHPLAIRAHESKWFIDFCDSEALDESKDNAGAKALLIEGMELLPWLYSSLFKALGLDVPRAIWGMEARDEHENLFTELYVHQTKPLWDNTQAIGLLKEAAASAQKATTDALAPPPIAGRNVGRFVYLDNTPALMGLVPDGMLHSFPNWDFDPLPPAQEENIFSYDTQKVQWTPDRGAADNPMLGPLPNGVGRRELEQMLQQVIRDGAPEQVRQALEEALGHNGQNAEASGADEGAEDEAHQAEQQAGLWQNFMDMIWPVRTLHDGNQSDSDDDDRYLGPGGWPSDDDEDEIPPLIPAEATQSQGPGGARQRDSHSDDDMPHLEPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC21</accession>
    <name>A0ABR1XC21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Scd6-like Sm domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000828</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674916.1">
        <property type="nucleotide sequence ID" value="XM_066805143.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038203"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="7">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="DFDF" evidence="4">
        <location>
            <begin position="442"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="5">
        <location>
            <begin position="503"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="6">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="394"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="472"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="1">
        <location>
            <begin position="503"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="2">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="531"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="559"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="570"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="593" mass="60158" checksum="5287108084CA954D" modified="2025-10-08" version="1">MELTVSRISLISKSDIRYSGILHEINSEESTVSLENVRSYGTEGRRGQPEEELPASDQVYEYIVFRGSDVKDLRIEEGPATKENKPPAVPDDPAIVGARARPVGPAGPAGPAGPPGPPNAAPGPNQGGFNPSPFQQPGFFPPPGPGPWGGRGGGPGPGPGPVPDPRFGGMHYPPPGWFPPGQGFPPGPGPWNNFGYPPGPHGPPGPPGAPGLSGAPVAPGAPGAPGQGMRGTPQQDNKPTPIGAGPGAPPGIERPKPAGTPSQGEAAAEQKAVAQPPHGSAPAPTPPVDSKPSVEEVRATAQSLNANGPAKVAHQQKNVPTGPRNNNRVTPAVPFTGAPKAGPSGQPGPQITAAAASIKPSTTGNAPPSAASIRDATQQAKDAVAVAMAKLGNASAAPGQPAANGTGNAMDNLTKKVNEMRVNATRGGPSTRGRGGRGSRGGAAGKIDVPETDFDFQVANAKFNKQDLVKEAVAGSPLGETAPNGSGPDPEAQEVADEPAPAQAYNKTRSFFDNISSESKERSESGGQKPGGREWRGEEQRKNMETFGQGSVDGGYRSYRGRGRGRGRGGPRGGGRGFSRGGGFRPRGGDAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC89</accession>
    <name>A0ABR1XC89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675019.1">
        <property type="nucleotide sequence ID" value="XM_066805246.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038306"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055100">
        <property type="entry name" value="GNAT_LYC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053013">
        <property type="entry name" value="LAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815">
        <property type="entry name" value="LYSINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815:SF4">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13527">
        <property type="entry name" value="Acetyltransf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22998">
        <property type="entry name" value="GNAT_LYC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="380" mass="42559" checksum="9B3FA924C78A415E" modified="2025-10-08" version="1">MTTSQDDRTTIITPNDGPIEAVFGEASPEQRVECFKQAGRSFVRSVPEDQWVAAEEQLGQLPLLRGKGCRHWCLYKADAPNEIISSLRTIRREVLIRDEQGIRQGTGYDIAMVATDAKYRGHGLASFLMRKVGEWADGPGAAPVTTLYTAVGPFYVKLGWELLPAPQVSFELPPGVSQDALQRKRGENQLLPTRLFGPDEMPDLCSRDIAQLRSQVEAYDLAPNTSLVTTLPIPEQLGWYQEMAKLQSLTWCEGREVKAVGAICEEADTWILWYQDLRNKELKIARVKPGYGDTDLAKQALVQLLSRAMEEALSWEGLLVKIAIWDPSSEVLGALEILGKELGFTPKSEMRDGVNQTSIRWAKAENRQTVFWPNEFYACN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCI9</accession>
    <name>A0ABR1XCI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001036</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675124.1">
        <property type="nucleotide sequence ID" value="XM_066805351.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038411"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09615">
        <property type="entry name" value="Jacalin_EEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF1">
        <property type="entry name" value="SPHINGOMYELINASE DDB_G0288017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00915">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046420304" description="Jacalin-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Jacalin-type lectin" evidence="2">
        <location>
            <begin position="308"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="450" mass="48943" checksum="D87BB436718C08F3" modified="2025-10-08" version="1">MKYTISNLAASAAIFGSALAASGDFNVLTMNVAGLPEILQGNDVPGDKTVNSKTMGSKFSEYNYDMIHVQEPHKQDHESNHANQDFNYHASIYETDNHPYRTATSGGVPFGSGLNSLSTKYFFNYNRVKWNVCSNASGADCLTPKGFTFMRVQVDEGIYVDFYNLHADAGTEPDDLTARAANLKQVADYIDANSVGNAVVVFGDTNSRYSRTADAIRVFRTQNGLTDAWVELIRDGVEPTAESLCDNPSKTDYCETVDKILYRAGATVDLKATHWGYESTKFLQPDGNILSDHNPITANFTYNPGTTLRQSDFWGGPWGNWFSDVPKLTTLSKPKAAAITVRGANRLDGVNVQLADGTTFTHGGSGGTATTLNLEANEFWTEAVLCQGQKDGHTRNFYIKATTSTGRTAEAGKSTSDCRTSTAPAGWQIVGFMGQDGDEVDQLAFVYAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCV1</accession>
    <name>A0ABR1XCV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine-threonine rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675298.1">
        <property type="nucleotide sequence ID" value="XM_066805525.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038585"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF4">
        <property type="entry name" value="CUPREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045163017" evidence="1">
        <location>
            <begin position="18"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="343" mass="33418" checksum="C519B3C8EB0629EA" modified="2025-10-08" version="1">MKFSAALSLAIAPLALAKAVNNVYPMRRTEHKGASKGAAKGAAGGALAGGALAGGALGAALGAGGAAAVNAGSVTQIILVWANPGGGAATTTMNEQVTVTQTVTAGAPPGASPPLPAAAATHSVRSLSEPAFADPLLLAVPLVSYTPPAEVKAKKGDMVIFSFMAANHTATQSTFEKPCDAMPGGMDSGFQPNANNTVNPPPQVAMQVMVETPLWFYCRQSTHCGKGMTFSINPTAEKSQALFQSMAIAQKGQGAPSAIVGGGAANGTAPPLPLLLDGGAAPPATGGAAQGGMTQGIGQLTPGSGQCVCAVSCAPGSFPAVAAQGLGAFGGMPGGMPAEMAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEF3</accession>
    <name>A0ABR1XEF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675742.1">
        <property type="nucleotide sequence ID" value="XM_066805969.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039029"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="4"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="91" mass="10575" checksum="FDE7F58253379250" modified="2025-10-08" version="1">MASFTCFKLLPPELRQMIWREALLEEVESRLVIVYRVSMRVMPHPSLAMNVMNANRESRNYAQNQFYDVKLDVHTLVAPDLDMGTELAAYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ98</accession>
    <name>A0ABR1UQ98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Allantoate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_015310</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660509.1">
        <property type="nucleotide sequence ID" value="XM_066819624.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052684"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF40">
        <property type="entry name" value="THIAMINE PATHWAY TRANSPORTER THI73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="41"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8061089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="488" mass="53344" checksum="96F396AF1BFBA2E9" modified="2025-10-08" version="1">MFSEKADHAEKTPAPDPETQVPRPADADAALEFMTHENMGTMAEVDEKSLVRKIDWRIVPLMLNYANVMGLQEDTDITGDQFSQLALVFYVTYLAFELPTGYLMQRLPTAKYLGANVTLWGLMVALTAAANNWAALVTLRVLLGCFEAAVAPALILITSMWYKKSEQPARVGFWYLGTGTGTIIGALSSFGFQHYASQNFRSWQIMFLLFGLVTIAVGLLVMVFMPDNPMTARGLTHAERVFAIERVRENQTGIENKRFKWHQARECLVADPQTWLLALITVASSVPNGAVSSYQGTIIKGFGYTSKAAALLSVPSGVVSCISIVTACGLGARYDARGPFVIAILLVGGVLGGGLLAFSPSDNKGALLAGNYLTNVIGSSLPLLYSYSAANYAGHTKKVTMNAILLMSFCLGNIIGPLTFRDADKPSYLPAKIAIVVTSALACVLTGILMAYYAWENKKRDMLGVSHKDNSEFLDMTDRENLEFRYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT28</accession>
    <name>A0ABR1UT28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660693.1">
        <property type="nucleotide sequence ID" value="XM_066818505.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051565"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="210" mass="23901" checksum="6C27284BC5C285FA" modified="2025-10-08" version="1">MPGSYPKGTDDGIDFDQSADIEARYLPFVEDLIMRHVEGAETVVFFDYTVRRACSTKLPANHVKKVHIDQSPKGALGRARRHLDKHDWDMVSNSRTLAEDDVVPVQQIYPDYIGETLAVKYREGQDFWYWSAMTPKDVLMFQCFDSNGNSDPQGLRHSQCAHGSFELNEDGKETFTRCQAFGIPIELHMNSTMLIQLVYHGLSRPPTSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT36</accession>
    <name>A0ABR1UT36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_015411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660610.1">
        <property type="nucleotide sequence ID" value="XM_066819725.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052785"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8061190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="402" mass="45953" checksum="C39B6A8833D12341" modified="2025-10-08" version="1">MSAEEFRARVESGKVLVDSHDRVLRISFIYLDEGLWDGNGVFDVVDQLHARGWSFGQGELRLNRTLDIFYLTQIAAGIYRSSDQTEGDFPSADDFDAFYAQHRPLLGPHAWRQYYSPALLAQAISARFYRLPDLQDLPDSSGPLGQPRTRKKKGGAPTLPVAAMTQMALFTLQQTIARQRKEDHPTSVQPYSETQARFWLKYMGMDSPDDRLHSSSSNSSREAWNPNEFGIGVAQGAFDIWAWEACYSRERWENSTDAPPLEPDLDGTRPSEVRWCGWPDGAGAKETEGFHVADELDYAMRSHILLALLHAAMESETETEAGKQMEELRRRMVGAGRIDESRAEQWIRQAWMVMEPYLYVHKRDDDPSELLRQILVENGQLFARWKLSPSSPEFDFELKPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT48</accession>
    <name>A0ABR1UT48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014182</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660684.1">
        <property type="nucleotide sequence ID" value="XM_066818496.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051556"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="5"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="269" mass="29272" checksum="1C6E0F6A97F81D26" modified="2025-10-08" version="1">MASKAAHKRLTREYKSISQNPPPYIEAHPSDSNILEWHYIITGPEETPYYGGQYWGTLIFPSNYPFAPPAIRMHTPSGRFQPSTRLCLSISDFHPKSFNPAWEVSTILVALLSFMTSEEMTTGSVSSTERERKFLAARSRWWNSTAGGSQKNAAGKGNVKAGDGGAKFRAEWPEVDKENWAWMAEHKIDSITGQSANAAGASCGPPGLGIAAGSGGQTQAVVDAVVQRRDAAGRSWLRNKWIIGIGVILVYTALARWLGSEGENQSGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTD1</accession>
    <name>A0ABR1UTD1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660489.1">
        <property type="nucleotide sequence ID" value="XM_066819604.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052664"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046026927" evidence="2">
        <location>
            <begin position="20"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8061069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="771" mass="86349" checksum="07D7A26A4B3E09C9" modified="2025-10-08" version="1">MKFPSTLLPVAGLLHGAAAGLTGLALRGEHQPDSQTMAAYEKVGLCMYYYNKDMQPNWQKGMEPCSKYCQNNGVHGYSECDYTSYMNTNFEEPTTFPTYEDDDGFPWVPAPCKCENKVVEYLTGEIVEFVAEGLEKLGNILCAVFVSAIKEIADVGLMFVPGGASIKGAGQVIQYAKSAYENGMSAADFYNDWVGQACGVPDWSFNLEDMFTNLVDAPDSLMGEKEDEERKKKEDEEEEKKKKEEKEKQSCKVKRAPEPYVPPPKRKVNKFDEEERRTTEECIGGKDQDVVHITRTHSDIGYYIQERKDIPKIVCRKEHTQACYHYRSVMSRYSNTKDMTEWTCQQTATSHAKGWGNDGTATNSWGVTALVAMPGSRAKMRGQHWFPWANGFIYHERAMENGQQKLGADKKPVWKGCERDEFPPRYFWPGDDKAPKHMRQLVRLLPDDQNKGAGQLWNGFCNDNNAASTRKYQQNADTYVVSAHLKSVKGEEEQEVEKGTTTSITTVTVSTLRAIFSISEFEGLKPEPYDGLEENQCYPRDLIDDPGWALLTDDEWYKSEGLQHAPRTADYRRSPTKAQVDAAKARIAADTNRKGKLEALDDISLVELTKKFTLKDEAKLWKKLVGNGDGQIPIELWGVLPSLPPFPKPAGVTRKKRHGVSLDDVDVASPHNGTLALEDRDTNADLDGDDHEVDLDSLTDEELEQWLAQYEEVARRMYVLAEEEELTPTSPPVVEAQATMAAVKGEEGLLRGEPAAVGSEVTNGLPLPTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTN8</accession>
    <name>A0ABR1UTN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014394</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660896.1">
        <property type="nucleotide sequence ID" value="XM_066818708.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051768"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12160">
        <property type="entry name" value="2-Hacid_dh_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="103"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="314" mass="34095" checksum="84037B538F9B7421" modified="2025-10-08" version="1">MKLLYPTSLVLDAQSLEGFSVTLHPYDVKTPIPDEHADADILVTWTNSAANLSDAAKRLTKLRWIQSLAAGPNDVLSAGFDTSKVLVTTGSGLHDHTVAEHALALLLNAARRFYEMRDWQLQAKWPQHLGGPQPDRPKDKFTTLRDANVLIWGYGNIAKTLTPHLRGLGATVRGVARTPGVRDGIEVYSDDKLAELLPQTDALVMILPGSDSTRHVLNADRLKQLPNHAWVVNVGRGTSIDEDALVAALQDGQIGGAALDVFEKEPLPESSTLWRAPNCIISPHAAGGRPQGAEELIASNLRRFLAGQDLKNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTY2</accession>
    <name>A0ABR1UTY2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660984.1">
        <property type="nucleotide sequence ID" value="XM_066818796.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051856"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="233" mass="26047" checksum="D60BCA4A3A4BD3A1" modified="2025-10-08" version="1">MQQRPKAYLFDVFGTVVNWRHSLAKGLEASARKVIEGTSTGVVDEAVLARARSMTFSDWEWFAFQWSRYQRYIDSDARPKETGDREAGKPATFIPQEELHRRNLDTLITEFQLDGLWTTSDQTAQLLHLWHELDAWPDSAAAIARFAKLGPSAALSDGPVALLTSLDARNGLRFSEVWGRIRGGRTSRTRACTWARCGGSGSSRGRWRSWRRTWGICGGEEVRAAGALCGEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUB0</accession>
    <name>A0ABR1UUB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661102.1">
        <property type="nucleotide sequence ID" value="XM_066818914.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051974"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13854">
        <property type="entry name" value="CuRO_1_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13880">
        <property type="entry name" value="CuRO_2_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13901">
        <property type="entry name" value="CuRO_3_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF502">
        <property type="entry name" value="MULTICOPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045751620" evidence="3">
        <location>
            <begin position="18"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="70"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="197"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="412"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="574" mass="63125" checksum="F0941356888A9C04" modified="2025-10-08" version="1">MIPSFFLPLVAAPLVAGYAINPFQQITPRSACEGNTADTRSQWCDYSINTDYANEVPDTGVTREYYLDLTEVEVAPDGISRYAMAINGTIPGPTLHADWGDNVVVHLTNNLKTSTNGTSLHFHGIRQNYTNDNDGVASITQCPTAPGNTFTYRWRATQYGSTWYHSHFSLQAWQGVFGGIVINGPATANYDKDLGLLFMNDWSHQTVDELWDTAQADGPPQLDNCMLNGTNTFNNSDGTVTGERYSLSLEEGKSHRIRLVNTAIDTHFKFSIDNHTMTVIAMDLVPIEPFTADVISIGIAQRYDVIVTADQGAIADKFWLRATPQSACSDIADPSNIKGIVYYGDKTDGEPTTLAHTFEDNCDDMDSSLLVPHIKATVGPNAWQSTNNVEVGTNDDNMFRWFINSTTMIVHWGNPTVLQVHNDETTFATSNAVLQLATAEQPSSEDWVYVIVQSDLAVTHPVHLHGHDFHVLSAGEGAYEEGTTALNLNNPVRRDTAMLPAAGHLVLAFKTDNPGAWLMHCHIGWHTSEGFALQFVERQAEIPGILDTQRLEDTCSAWNSHEDAVAMVQPDSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UW18</accession>
    <name>A0ABR1UW18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_015199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661701.1">
        <property type="nucleotide sequence ID" value="XM_066819513.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052573"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8063102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="483" mass="54996" checksum="C09EF0F4BE9AA577" modified="2025-10-08" version="1">MSYTLVIQVSALETSQELLRWEDLSTQATARGVQLPNEAFKRSLCDEVCKDLLKHETDPFVSRGQFWLLVHQKAATLWLGESEASRFATRWADEGKISFWCGVYGETPCSQQYVEFWVREKNWAPKKPLDDEVLKALDGRNHHILAPHGLVVKAVSRNMAMCLTFLITDVVLAGSVVAPGVCALREARRCHPQWENSSDRTAIIEAVQQLMPDKDNETLWALEEELPQRIWGLILGETWEEIGNTLHSTAVQLGVFPNQDGTKTPLFQLQLRLDHQIKKSKEWVGVVSLRWDTTIAAAVADPSSTRAQLARTAAFLRVYWRTVRQAHEEEKTFSRLDRCAHWAMLRYPDLLALPETFDLAAAAEINGEWTATHPARVGESHFDQVRAQKLAYVLFDMIDDRLPAVVQDCVAKVDIKYRVKALSDWVDKGGWEFYPVKGPRNRWNRRRWAGPAAGDAADAIWRSRYDDMQVALMEETDGEKGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UX10</accession>
    <name>A0ABR1UX10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660942.1">
        <property type="nucleotide sequence ID" value="XM_066818754.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051814"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="126" mass="14342" checksum="BA535C86149F3617" modified="2025-10-08" version="1">MPYALCSTNMRIEVPSSSSPPAASKPEPTDLQVLGALFDLKDKKNVNQRFNRLSAKMGWFKTADDGPSTFGQDWRKQQGWKGDWPEAGKFGKWGAVFVKIRRDKKNMPCAFCQYTVSRFCRVVFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYH2</accession>
    <name>A0ABR1UYH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661709.1">
        <property type="nucleotide sequence ID" value="XM_066819521.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052581"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="274"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8063110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="368" mass="41590" checksum="26C02CDD55DF93E4" modified="2025-10-08" version="1">MEAPIMDLTSIANQIKNIAKGKDAVADNSNRILAIKKVSHVGYIIRARVDGLIRYYSVTHEAAANFPKGWETGSPDAILPPRTYPDDLKCIHLRKPGLTEFFDQKKPSHQRPKIQDVQHSVSADYETFEKLGKIPTPRFPNRPCDDRINIVRHPRIHNHQPMVMKVVEFPETWTFPQASQSPSEAPAPAGSKAQKLNVGSDGSEFNERVMRLEMRMHQKVAATPSLAGLVPKFLGLVTERGRGVIGYVSEYVPDAKSFKQILEDAYAAGYKGFRLSEADREACRAALKRLHEDARLHHGDMHAGNVLRRGDGSVVLIDFEETFHLDKEGWVYDSFESAESERQRMERWLDGTASDWHQLHTMSLEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V255</accession>
    <name>A0ABR1V255_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661771.1">
        <property type="nucleotide sequence ID" value="XM_066816079.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049139"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="96" mass="10212" checksum="7E2F31CC4B0D8083" modified="2025-10-08" version="1">MFSPEVIVALALGIPSLFVAVAALWIAYLTYTRQSPPHVNRTTSWPPFSYPPLSPSGGSSWASSGCSVGDDDPAVPQAAFPAEGQPVRRRPVELES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2U7</accession>
    <name>A0ABR1V2U7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662271.1">
        <property type="nucleotide sequence ID" value="XM_066816579.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049639"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046351">
        <property type="entry name" value="UTP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44163">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44163:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="721"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="847"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="761"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="898" mass="98823" checksum="4A61915FD36EF933" modified="2025-10-08" version="1">MDIHRCRFVPYPTSAINAVAFSCSQLTGRRNPNLVRLAIGRANGDIEIWNPLGGQWHQESILHGGKDRSIDGLVWVTEPDRLLSDGRRIQGRLRLFSIGYTSTVTEWDLEKRRPKKQATGTHGDIWCLGVQPLEDSAKSTKTAKGGSSAPKTQKLVAGTIDGSLVLYSIEDGDLRFDRVLVHSTSKKTRFVSICFQKRNIVVVGCSDSSIRIYDIRSGHLLRRMTLGSDLAGGAKEIIVWCVKCLPNEDIVSGDSTGQVCIWDGKTYSQAQRLQSHKQDVLSLAVSADGSTVLSGGMDRRTALHRKTSGTSTRWATIWHRRYHGHDVKTMTSFESEQDGVSAPTRTRSRDGEPSSAFASPSDTTPDERPRARLIASWWDREVHIWRLQKPLKDIVNETGVDADVTKNRKLLAREANITSASINSNGSLLVVSTTSDIKAFHLTAIPDPTMDELKIAKIDVPLSVAALGAERLKISPDNQWICVVQECNRVSLLRVSNGSEPDDMPVISHKAVRLHRLKRDIPKHVAFGGLGEYERSVTQIAFSPDAKMLAVADVAGYIDTWIVHGPASALQNGVNGDAQDDGSSSESDSDDSEDESADIDPAPVAWARNPNAALLPKLRNAPTLLSFSDHIPSGNTESTDDQDDYVLFAATAKPQILFLHPTIGGITPWSRRNPTNRLPIEFRNIRDLVKGAIWSGDRIWMYGNTFVAMLDLSQDVAEDTPDESSALVLQDNQLDQSKKRKRGPDTGAGNKMKRGAAGPTKVEHFKNGKSEALNLERRATDPMDTDEQSQPGEDSDEDDSDSEPRGELALKRKAERQQQKAAQSGQGIGFWHTLKYRPIMGIVPLSGPEEEEKETNGLAVTSTANGQASRKTLEVALVERPLWEADTPDRYLGEGDYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3A7</accession>
    <name>A0ABR1V3A7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662417.1">
        <property type="nucleotide sequence ID" value="XM_066816725.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049785"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="1">
        <location>
            <begin position="5"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="223" mass="25173" checksum="A5CC70388BBB200E" modified="2025-10-08" version="1">MKQGLPGTLNTLILFEDSYKFYDSLPNPVVPNPWLSDVMIPYEDLGAVFAQKTATLQQLAIPFMVQAEEIVQRCQPTWSWPRLESLALTSQLLQNDWGTRSDLENLLCRTSVLVQKMPKLQTLVLWNGGKGHACAFIYRVDGGSASITWRGTWKSSFSLRVVEAWQLTASKLPRCPEVEVKQEDITGVIHSHGDAIYHLKLPCQVIDPASLWQIRREAYSSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3M6</accession>
    <name>A0ABR1V3M6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012538</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662544.1">
        <property type="nucleotide sequence ID" value="XM_066816852.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049912"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="7">
        <location>
            <begin position="228"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1965" mass="222594" checksum="E440B1D7BFCBAE88" modified="2025-10-08" version="1">MNLDKIYVTDVSTERPDPTTGSRQWQIRLQINEFYIEEFIIHDPRPPAFYKLQLNDYVRESAHVLARKFARLGRAATNEHADLGAWHDDLAAYTQSLWETLKLDSYRQTQRRAFRRESTGCIIYIIDQERVNEHHFPHPVLSIQCLKWELLETACPGEGWPSGYTLAVSRVVDAKNVVRKPYLEELEEVQKSKLHGVSTIKILLVVARDLTKMGRNRDVGPELTQEPLMRLQWMLNRAKTRVLLEVVRPGSLQSLRHHLTSRRGQGMHFNIVHFDLHGDEDILGKRSVSRLVFATGKHGSPKGVVSEDIKDVARLMHLELIEHVVMTTCWSAYEEAGSVYSMARQLVHSNVRGVCAVWGPTGTDCVSAFNYAFYTQLLREDESFEAAIHSARRAIRSAPERWPGARQYRDDFLFVYYSRDNPIKPVAPRQSLSETLKSCTRYIFGSPRFNAQIFRRAEQKQHIPSRDNGGGIIPLNLLLFELEVYLQVYRIVYASDSEEHQEKMKETIQNLSKMWLRTNFIDEVQYREIPQDNTRSITTLPRPHHKESRHTHGYLLGHRLPRALGGTLHVIDGLDDVFRPPYGSSQARIKNRGNTIQMLRKFLIELSANDYVIFLGFRVESNWMPQEWVKSCPRDMKYWSHGSSVYEDALEKPNSLDLVPNFANECRNLPISMHRAVPNDHPNDHVIYPVVMGGSDLELTFGIGELVRGEPINPVNVSFSGGADSGAWVGREAILGGRLLDWKEWPLGFYGCLLFGKLIDVWQCTCLPLLTWALNQGILLLTYGANSGWLDFLCGMLGAPLDWAKQTCRHPQLQQLPGLPWLCHTVACLRGHAMLMAPEPRPNSVGFLQRARSILKSDSANSGRVDDELKVVHNPLGAEGPLIDVVAVHGLARGFKTWTWGTGTLRRQNWLEAGLAQDECGKGIRILTYSYDPDIFESHTHVRQVLYSRAHSLVQAIADHRRRSKTPADRPIVFITHSLGGLIVKRALIFSSESHDLGLRSIELLTGGVVFFGTPNDDTEPKSLADVIQKVSWLGAGHDTWANRSGTTLENDAKWLDNELEAYKPIRSEIRVLEVYEGKKTSFRGIKDIVVGEPQSFYAGSDVSRLTLQRKHTGLVKFDGENDPCYRKFMGRFRTVLDDARGRAARKLRRQQSLKLMLGGDNIAYLQTDFNIPSTIPESSAQIDIRSGLTSNLRNLLQEQRKDTDFNIVTLFGPQGVGKTTLARNYCASVEDSVCFSFWIDAESRETVITGYLHLLKTIVNYYAEKYFAKKLPNPRDARARVEKHLGIRNIEEMLEGESIKRLEPVDVQSAIKGAKDWLLREGNNWLLVFDNVHPEYNFLEFLPLSRNGQMILISEERSYCPWGKTIEVPQWAEDDAIELFQKLSGSRCSDGEKTENLFKEIVESLGSQPLAISCAATYVKDRARTPEQFLSLLQNPDSFLDGLSSGSPLTSGLLQVCSILSSHALPFGFIEKITQELSHLDERRDSWASLGNHTEKLRPVLKDLEDNNVLLRVPKGSSWSGTLLTGEMASSVDQFLLQKGARNWIQNTWMTNKDRKVRSTWMATFCCVRLIRLQDANSGLQEVQAAERQIMPHAKACFDLSSLLQSDSKKYEEIEWHVLGGLFMRHGAGAEATKCFRLALESPKQMAPVEKAETLMALSSLYQLRGDLNASRKMLDRIETAEVSREDSRLGRTVALAKALGEAAKGDFETVKKQLRILDEHQEKDLGAVDGRTIFTVHKFAATMKNLDQLDDSQALYRRAHLSYSKLLGDNNAVTLDAAEELAQILQLRGAFAQAEDLFLFTVRVKQATLGPAHPSTAISQAKYAALLDGKGDFEKAETMYRDAFTTMRGALGTSHPIYLATRENHALSYRRRAHQRPVKVKANTVAPLSSLSEEEGREKALERAEKIFDEVIEAKLGNTALYSEEDVQSTRLKLAKMYESEEFFRQRTGQKRLPLRRESSGFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3X8</accession>
    <name>A0ABR1V3X8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase family 71 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662647.1">
        <property type="nucleotide sequence ID" value="XM_066816955.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050015"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11577">
        <property type="entry name" value="GH71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005197">
        <property type="entry name" value="Glyco_hydro_71"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03659">
        <property type="entry name" value="Glyco_hydro_71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046262530" description="Glycoside hydrolase family 71 protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="49675" checksum="2415DD6E08522687" modified="2025-10-08" version="1">MRKGAFVPAVAALVHLAAARDVFAHYMVQTLWADTNHAVQDVIDAKNMGIAAFALNIGNVTADWATDATSQLFKAAKDNQFKLFFSLDLAQHKDAYYYSDLLKQYAGHDAYYRAGPDQRPFLSTFSAQGTDANYWASFLGSFGQTNFYFVPNFDDTPNYFDNPRTWMNDWGKAVDGVFSWETAWPRNSNTPSNVSSVQDENVLKAAHAKKKAYMMPLSTLQYKHWTGQHWYRPGEVNMPQRMTEILDMGDRADYVEIITWNDGGESHYIGTLRMEGIFDTMYEYANNDNYSHVAWQPVFTSFIYAFNNGLKASGMRPPIDKQLVGSMWYRAIKRGASCRSDPEGRPSGSGAAQDAVNWAVVAADYGLENLRLQIWSGGQLIRKVALQPGLNYGSEPGLATGPQYFEVIDTANNNKILMKGQGSVDVKAESIGYCNYNYVVAGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V416</accession>
    <name>A0ABR1V416_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662656.1">
        <property type="nucleotide sequence ID" value="XM_066816964.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050024"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="17073" checksum="31D4E7058CA00EB8" modified="2025-10-08" version="1">MVNYLVSSHRPDLTRAVVIGTAAAEKIVEPYKVIKWQIGSKYKYWHTLGEDGHDKGKDQDRSCFCRQYFVRWACEHWVKLPVRCGKSVSPITGNPVICKRRGIVTQVVMDHISCFEECDDCTAFTKDANEAFDELEREARCVKREASPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V434</accession>
    <name>A0ABR1V434_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Secreted glycosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012703</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662709.1">
        <property type="nucleotide sequence ID" value="XM_066817017.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050077"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF42">
        <property type="entry name" value="PUTATIVE SUBFAMILY (AFU_ORTHOLOGUE AFUA_6G13760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="3">
        <location>
            <begin position="112"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="2">
        <location>
            <begin position="354"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="812"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="824"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="833" mass="91821" checksum="D039322D73DD51B6" modified="2025-10-08" version="1">MAPFLTSGFPRRRRVLVIATFAFFIWALLPVKSFNPPRRLLNSVMAAGGLEIGATTLTGSGSVGGILRYVDPLIGTVNGGHVFPGATLPYGKDLKSTVLLIQATWILTDFSGMAKAVADVDNWGEIAAGFVSDSSKVTGFSHLHDSGTGGSPSLGNFPLFVHVGCPDDSYLECNYPGAARATERIENTTVARPGYFSITLNNSVGYEMTAATHTTLFRFNIPDQEDILLPTGIVVPNSPVLLLELTDLGRTRRGGDIQVDPETGRMTGSGKFSPSFGRGQYSAYFCADFRGAGVRKTGTFVNTKANETVKGMGRGSSSGSTMPAGSVGGFVQFDRPLGRQFLARVGLSFMSVAQACQNGEREIPDFDFDSVVLASEQAWSEKLSVIQVDKVDVNNDLLTTFWSGLYRALLSPQDYTGENPLWNSSEPYLAQHPLLTLVDPKEQTRMVRALIDIYKHEGKLPDCRMSFAKGYTQGGSNGDVVLADAFLKKLHDGIDWGLGYEAVISDAEIEPDDWTSEGRGNLEAWKTYGFIPNDDDDKIIRDFTIALMARGLGKKDDERKYLERSKNWENVFDPDAEDQYTDGGRGVVGSEFKGFMQPRSRNGAFQYQNMRLCSPVYEMHKCYFDTVYDTYEGSPWLYTFYVPQDMASLIVTLGGKEAFINRLSYFHSSGIIYMGNEQSFLPTYQFHYGGRPGLSSYWLHQYIPGQFNSSINGIPGNDDCAMGAFTTFAFMGFFPVAGQDVYLLTPPLFREVRLQTPSGKPATIRNIGFDPSYKAIYIQKARLNGKPYTKNWITHDFFYHGGLLELTLGPEESEWGTRDEDLPPSSSTQANAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5A9</accession>
    <name>A0ABR1V5A9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662249.1">
        <property type="nucleotide sequence ID" value="XM_066816557.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049617"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF113">
        <property type="entry name" value="PROTEIN ACTIVITY OF BC1 COMPLEX KINASE 7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="77"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="295" mass="32574" checksum="EB7BDF6843B0AE0F" modified="2025-10-08" version="1">MASGKSNAILSLIPQLAGGATVRARVDDLIRYVNIPKDVLSSEPGLTDGDDPKILNLDYPAGVKCLEVYLGFAELTIRPLQLELKGIEGIWYPVSLDYDTFEDVVPLPGKSAEPSDRVCTVKHPQLKSYGKMVMKIAELPANWPAPNGGLFSSKASLETEMAREIRMHRDVVETGLGIAPVVFGLVTEKERGVIGFVMEYIEGVRSFDELKKEGYRMTDEDKKGCRDVLQKLHEKGFLHGDIHPGNLLRRPDGSVVLIDFQATSRVNSEGNVEGFAVASQTNERQMSLESWLATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5P9</accession>
    <name>A0ABR1V5P9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="3 6">2.1.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013268</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = 2-dehydropantoate + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PanB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="3 6"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663274.1">
        <property type="nucleotide sequence ID" value="XM_066817582.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050642"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001452">
        <property type="entry name" value="PRK00311.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881:SF0">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="265" mass="27995" checksum="3A0DECEC88BE60C7" modified="2025-10-08" version="1">MGTLRSMYKKNEPITMITAHDFPSAHVADAAGMDMVLVGDSLAMVALGMEDTSEVLVEEMLLHCRSVARATKAAFTIGDLPMGSYEISPEQALDTAIRFVKEGRVQGIKLEGGKEMAPTIAKITRAGIPVLAHIGLTPQRQNSLGGFRVQGKTADGAMRVLEDALAVQEAGSFATVLEAVPAEVASIVTQKLSIPTIGIGAGNGCSGQVLVQVDMTGNFPLAGSSPTYHEEVKARSYPAPEHTYPISKEELEVFSQAVGGKREGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V619</accession>
    <name>A0ABR1V619_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013390</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663396.1">
        <property type="nucleotide sequence ID" value="XM_066817704.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050764"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF10">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 29-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="200" mass="21163" checksum="D416EFFAEF9EC0C2" modified="2025-10-08" version="1">MAPKLTADEIDDLIYLSRAGEDAELTVLLKELADREKVTIADVLDAAKDESGATCLHMAAANGHSSKCIFHPHRLPAQPSSEESAASQQPTSYINVANQFGNTALHWACLGNHLDTVKLLLSRGASPALANDKDQIPLDMAAFNNHMAIVEYFLSQSRNVEAENAKEGGFEGAVKDVDMDAAEADAKVEGKAEAGAGASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V688</accession>
    <name>A0ABR1V688_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663467.1">
        <property type="nucleotide sequence ID" value="XM_066817775.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050835"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="179" mass="20143" checksum="A050E19FE4D1C02C" modified="2025-10-08" version="1">MQDNDLKIQRAPYNHATWANTAPDYAGQLEKLCMSGCDMPYLWGAFLKVGVSHLRSPGMYGTIADEIPQMELEEDIDVSGGEDYMNLFGVFIYDINDRHDVGARVPNLVYFPSATCDGKFDLWDAKDKDEIKNWVLSWPTVQEWSPFNGGQDNFERNVLGQKAVVASPQLVAAARFSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V763</accession>
    <name>A0ABR1V763_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Heme oxygenase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013778</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663784.1">
        <property type="nucleotide sequence ID" value="XM_066818092.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051152"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19165">
        <property type="entry name" value="HemeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002051">
        <property type="entry name" value="Haem_Oase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016053">
        <property type="entry name" value="Haem_Oase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720:SF0">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01126">
        <property type="entry name" value="Heme_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="310"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8067031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="38953" checksum="7E1479A479649C45" modified="2025-10-08" version="1">MPSRIEETACHLPLASGYPPHVQDPSNYISGLLHLTPIYNGFESLWREFLETPQPSDTGVDPTEHSCEVCKPSAAVHHSPHVLDAPHKPTLCSRIHSLLHHVHTPDLERTEALKADIVSMTGWSTELLAEQLSVAEESPVLAAFLMRLRQSVRARPHVLLAYAWVLYMALFSGGRFIRASLAQVDPSFWNANCLSLNPELPLRFFTFDTAQGGDEIKSSFKERFAQSSGSLLTEGEKADVVDEAKKIFEFMIEVVGELDGVCGSGPKPQDANADEGIMSRMSRLLGLRTRDSVVITKERREWAKLFHASRIAEDSGSGSSENERSNTPSPTRGMKNQSNGEHVHWAGSTRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V764</accession>
    <name>A0ABR1V764_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663786.1">
        <property type="nucleotide sequence ID" value="XM_066818094.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051154"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="89" mass="9558" checksum="8A4D5C0B127DD1D1" modified="2025-10-08" version="1">MTGPRASPEAHTLSPTTTSCTGTCATRRGSTPRPLKSARRVRDAAGPVTSIRQARDPTRCVDADSRQAFRVQAQKTVGELAPPLENPMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7E9</accession>
    <name>A0ABR1V7E9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="4">1.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012751</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-proline + NADP(+) = (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662757.1">
        <property type="nucleotide sequence ID" value="XM_066817065.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050125"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="6">
        <location>
            <begin position="11"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="7">
        <location>
            <begin position="176"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="287" mass="29758" checksum="E74573C351744B89" modified="2025-10-08" version="1">MAPANLHSANLAFIGGGNMCAAIVGGLLAKDIMPKDRITVSEPWEVNRQKMADLGVQTTTSNTHAAAAADLLVLAVKPQVAKAVCHELAASWAARQELPLIVSIAAGITLGSLSDWFTGPDGRAPHVVRVMPNTPALLGEGASGLFAGAGVSPADKDLVTAMLESFSKATEWVDKEELIDVVTGLSGSGPAYFFAMVEHLVASAKAQGLSEEQAMRLAKQTCFGAGKMLVESSESPTQLRKNVTSPNGTTEAALKSFEASGFEGIVDKAVRAASSRGEELGKILGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7F0</accession>
    <name>A0ABR1V7F0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663879.1">
        <property type="nucleotide sequence ID" value="XM_066818187.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051247"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="106" mass="11900" checksum="A3F0F1DB237C4BF9" modified="2025-10-08" version="1">MSSRTADGQVKSSSEDYKEILDKKAFEARHPDAGKEEPTLLEKVTEYIPAVAKVLGTEKKEAEEKSPEPEHTPGPPERPHHDVNIEEFVREQHRSKKGPDGQIIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7J6</accession>
    <name>A0ABR1V7J6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662802.1">
        <property type="nucleotide sequence ID" value="XM_066817110.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050170"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="432"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="980" mass="106437" checksum="067C523AB8431ADB" modified="2025-10-08" version="1">MATKNEDGLSMSPPPYEAEAYAHHRQPRFRRRLHKPCSVPVLLALTLTFGITYLYVLLQRGTLLNRTPTKGSASSSTTIKFEAALKACAARYVRPAEPMPEIRETNSRWNAIRGQGETVVLRNATLFDGESFVSGPVDIRFSKGLITSVTPASNAESRIMGVREFDLRGRYVTPGLVDMHSHHTTGSWPGTSISEDNNEINSMFGTLTPFLRIIDSMKAYEKSTEIIASGGITTSLILPGSANTMGGEGTVIKNVLKSGDSGEYVVEEMLLERGLPTEDRHRYMKFACGENPKHSYGHERFGLAYILRRHLSRAKQLMDKQDAWWAAAAEQTRFMEQAGDYPEELELESTIGLMRGRIAMHNHCYEPEDMETMLRVTRDFGVRVRAFHHAIEAWQVPEMLKEYGDNITIATFAEISLYKQEAYYPNLYAGAILDRHGVPVAYKSDHFFESTNAKYVLSQAAIGHAFHLPAEKALQAVTSIPAKAIDVAHRVGYLRKGYDADIVVWDSHPLSIGATPQQVFIDGVATLKSEDVEKATGSYLEAHVAPLAPVDVPKMRVRKSETEAKDFCTSAKKKSRSFVIQGIRKSFLDNYPQLSNGIPPSGMSDNLTLVIDKGQISCLGTHDACRTAVASVATTNDRPMHVQLQNGYLLPGLTALTDLIGLKEIATQASTGNGAASVKEVRDPASIDHAKYGAYLDGKGFARARIGGVTRVVTPPELGSDGMLQGVSVGLKTSGTQTILDGGVFRDNVGLHVVIGDKNKAKGSVSQAIQTLRGILLENKGKANESVYGMVADGQMPLLVSVVNLAATQQIIAIKRDFPGVNMVLNGGHAAPLVANELADAGIPVILSATRPGFATWEGKDYLVGPPLTRSPASVLSEAGVLYAVAVKGDLPQGDSRIQSLALEAAWAAKYARISEHEAVRLVSRNAEAILGLEPSKDVVLWENNPLQFGASVVLSLEENKEGKLAVATCWPDDAADDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7Z2</accession>
    <name>A0ABR1V7Z2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycosyltransferase family 15 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664036.1">
        <property type="nucleotide sequence ID" value="XM_066818344.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051404"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF2">
        <property type="entry name" value="MANNOSYLTRANSFERASE KTR5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018153">
        <property type="entry name" value="Glyco_trans_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8067283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="49579" checksum="400CD7BABFD68C73" modified="2025-10-08" version="1">MPIPVLQPLRRRVRYLSPLLWLALALLLEVSYHVSRFRIPAPELELDPPFYTSCQEPPGNASAAQTRESAALVMLARNEEAGAAQHSVASIERRFNRWFGYPYVFLNDRSWSEDFMATIRATTNASVAFEVIPPEQWTFPASMDKEKAQASIEKQGRDGIMYGGLTSYHHMCRFFSGAFYKLEALKNYKYYWRIEPDVDFSCSITYDPFVEMARHKKVYGYTIALGEEGTTCPSLFRQVADWKEAHSIRSTDLWRASMSPSRLPWPLRTFAKHFPHRDRRGDSWNLCHYWSNFEIADLDFFRAAPYQSLYAHLEKAGGFYFERWGDAAVHSLAVNLLAEPRKLHHFADFAYRHDYYYQCPANARDGQLPASGPLNAAEPSWAPERDDGVGCRCSCDSARPRNVGAYCLSKLREPTSTKRPWRTWVLGWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9N1</accession>
    <name>A0ABR1V9N1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">C6 zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663416.1">
        <property type="nucleotide sequence ID" value="XM_066817724.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050784"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="174" mass="19317" checksum="4DE686510F5D57B7" modified="2025-10-08" version="1">MSSTQQQQSSDSNTFQPPAGFNKMSEQEQQQTYMEWAKQKYNEQYEAWIPWIEDHFLKWFTKDNKASYATKGKPWFFHPSASVHTCLHLNVANMSSPNTEQLGKTKITGVEQVDNLQDGVNNLAAGQVGQGGLLQPVGDLLSKEGANRAERKGKDENGSYLPTSLPKVPGGLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHM9</accession>
    <name>A0ABR1VHM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664544.1">
        <property type="nucleotide sequence ID" value="XM_066815254.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048314"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF8">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="17"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="465" mass="52730" checksum="4D7B19FB113916D7" modified="2025-10-08" version="1">MLTSETFNAFLNAIPVPELPATVRDAIDIARQLGLSYIWIDSLCIIQRDKMDWQREAGQMRSVYGGSEVTIAASSAKSAYEGFLKRPVHRNRGVHVRVTTSEHSRRQMFYTWADVLETQPDSTALADRAWCFQERLLSARTLYCSHRGLFWECRSTIGSEFIPVEIPYMAKTDLVLPEATRWDWDDVVRQYSKTRLTYSSDRLPALSGIATRQAEQRAKQKANQYLAGMWCTNLDKQLLWKRDEKLKERPAWQAPTWSWASIDGQVLPKPDASIFYRAKWYIRVIDVRTTLAGPDPHGAVTGGELTLGCASILCGTLDDTSERVYVDWSGAGPVRDESIQIQVSMDCASEEASRGPATVYLLPVAVSDARANFYVAGLILQRCGSGRGRFRRIGYFNSDRLRRYSSDPGTDESGLESEYPTDDEDLRQELVRLIDYAGPETAMEVCYGPMEDMDHRERPDKIIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI39</accession>
    <name>A0ABR1VI39_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HET-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664360.1">
        <property type="nucleotide sequence ID" value="XM_066815070.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048130"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="54"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="616" mass="69304" checksum="1E29D61AB07EFFDE" modified="2025-10-08" version="1">MEVDEDNADFYRPLDIDALEFRLLLVQAGEGDEPINCQLVHAFLKDGADRPPTRLSRTTEGIFVDGLEMMVPLSAQRALKCMRKPDEDRTLWIDAICINQNDVAERGQQVALMREIYSNTESNLIWLGEGEGDEEATTYCEAVLESVYGHAKGEMKDFAEFDEIACRTLPDSEPGGPLLKHHLATLFSSPWFKRVWVIQEALLAPKSLVHIGSHEMDFEKLLIGATWLSHMSYTLDLRPLDKYVGLLNCQRMYELGHRESDKSIDNILDQVPTFQATDPRDYVYGILGLYQNMTGREGGLLPPLLTPDYSKSVAAVMRDTGRYIIEQSPNLDFLRRLRHWPETAYEQTGVPSWAEPWHMRSSNYDMQGKGAAKDMKCNLYSADNAVGKREIGVTVATLNYDLDVLVLTGVIAGKVKDMSCVIDGSPKQLTDLMESADSPIHLDTIREEPETIGFALIAEATTTSERPMAEYARTNVLAWADFLVKHKERPRDINKKLGAKNLYIQPFTDGEKPEFTEEEWSALVDYDDAVSSATQDRRIFRTEAGNIGLGPKDIVAGDVVAVLYGCRWPVILRPRGDVEVEGYEFIEVCYVHGLMDGEAVQRHVASGQNDVVFHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIK9</accession>
    <name>A0ABR1VIK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_011275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664880.1">
        <property type="nucleotide sequence ID" value="XM_066815590.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048650"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF64">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="88"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8071072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="542" mass="59321" checksum="1C07FBAFACFAF2D4" modified="2025-10-08" version="1">MFAAKDERGQSEGPRRTSAELHASDRSVTSSHDGSESVHEEEEGEHNLDRFSTHHSMGPDVPIEARDSTVQIPGEVYDRLPNHRKLMIVALLSFCSFLAPASSTSVLAATPEVAAEFQTTGSIINLSNALYMLFMGISPLFWGPISQVYGRRPVTLVTAVAFLGCNIGSALAPNLAAFFVFRILTAFEGTSFILVGSSVIGDIYRPTERGTALGWFLSGTLIGPALGPFIGGIIVTFTSWRVIFWLQTGLAAVAAAGSFFLLPETIYHKRIDDLVGHSGLEKAKVLGGMVNPWRVIRLYEYPNLFLTGLASSCLLWNMYSLLSPIRYVLNPRFNLTTPMQGGLFYLAPGAGYVLGTFGGGRYADYIVKKYINKRGMRIPEDRLYSSLPFMGIVIPACILVYGWCVEYDRGGIPVVVVALFIQGLAQLFCFPSLNTYCLDVMPTQSGEVVASNYVIRYLFACVGTAVVLPGIQAIGVGWFSTISVAFLLCGVLCTMATIRYGRQWRQRIDAKKKARRYAEKRRGLPATSSSSPDHDDSQGEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKK0</accession>
    <name>A0ABR1VKK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664568.1">
        <property type="nucleotide sequence ID" value="XM_066815278.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048338"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="6930" checksum="782279D4A1DDA117" modified="2025-10-08" version="1">MDKLKGAIDSKVGGKSSQPGNGIERSADNTANQQADKIGGQAGIPASQNDTIHKGLDSKINEKIPGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT00</accession>
    <name>A0ABR1VT00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Polyketide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_009043</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665320.1">
        <property type="nucleotide sequence ID" value="XM_066813358.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046418"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="10"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="12">
        <location>
            <begin position="881"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="2387"/>
            <end position="2469"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="881"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1025"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2335"/>
            <end position="2367"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="913"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1083"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8074380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2491" mass="270590" checksum="BCD653A76BBAC051" modified="2025-10-08" version="1">MTITKTGSGPSPIAIVGIGLRLPGGCRDAQSYWDLLVNQRDARRPIPPERFNIDGFHKENSGASSLSMKHGYFLDEPVDRFDAAFFSMSQAEVARVDPQQRLMLEVMHETLENAGEVGWRGSDIAVYAGSFGQDWLQMQARDMQDGNVYDITGMDDFVLANRVSYELDLRGPSMTVKAGCSSSLIALHLACEALQRGDCSGALVGASNLLLSPEYFLALDNLGALSPDGSSRAFDAFANGYARADAVNAVYVKRLDDALRDGNPIRAIVRSTAVNADGKTVGLTNPSTEAQARLIRRAYEKAGICHPEATPVVECHGTGTATGDPLEVAAAVQVFGSKETTYIGSVKPNIGHGEGAAGLSSLIKSVLSLERLTIPPNIKFQTPNPKIPFAESKLVVPTGPIPWPEGRDRRISVDSFGLGGANAHVILEAPVKTDRVLMNSNKKPTASQRLLVFSAHTETTLKAMLDRYETFVGSESSQLKDLAYTLGARRHHHQLRSFCVTDGQSYQPTATVRSSDPKRILFIFTGQGAQWSGMGRELIRDFPTFRRDIQRMDRWLTVTASALMEHGRDINAAEYAQPLCTAIQIGLVNLLRSWNIQPDGVVGHSSGEVAAAYAAGALEMEDALLVAFYRGIASNQQTRPGAMAAVGLGRDEVSSLLSNGATIACENSKSSTTISGDLSAVEATLDRVRRHKPEALARKLKVDRAYHSEHMIAVGSAYRELISTITTTPGSLAIPFFSSVTGNATYDPTMLGTEYWKANMENPVLFLSAVESALESSQEFGLALELGPHSALSGPFRQICKDHGKAITYDSCLTRESDATTTVLSAVGRLFCQGVVPDFAAMNSGGATMSNLPPYPWTHDTSYWNESRISREFRTRAFPEHELLGARVIGGNDLEPSWRKMLSLREVPWLADHAVAGDIVFPAAGYIAMATEAARQLSSWSAAAFTIRALTIGSAMPLQNGKPTEIMTRLQPHRLTDSQDSTYFDFCVMSYDGTRWTRHCSGQVRTEDALTLSAEGTHSTTSEAKREVPSPKWYRAARSAGLEYGPAFQGLQDIFYNLSRGCLSAKLLPPAHSSSILHPTTLDQLLQCCILGSVKGHGRLLDRMAMPVYVEEMAISARDDLADLQCDAYTTSVGPGMISARGQVRTKDGPLALQAQGIQFRLLGNHASSEEDPLQELHLLEWRPDIDFVGLGQMVHQTQDISSCLELVERLNILCVLETTRILKSLDSTHHHFRRFKEWNEEYAEKMRRDGSRLVQNVQELHEMTSEQRVSAIKKVLAEALETPARDIALAVFRIFDDVVGIFTGAVEPLAVLLKDNLLMEVYNFFNLLDHRKFFELLGHKKRGTLRVIEIGAGTGGFTSTILPALVDSAGDCMFSTYTYTDISSGFFKAAKERFGEYNSIEYSVLDISKDPASQGVDLGSYDLVVAANVLHATPDLLQTMTNCRSLLRPGGRLFMLELCSEAKWVNYIMGTLSGWWLGEPDGRPNEPYIQSQQWDTILRKAGFRNMTAIMDQEPPYQLDNIIVASAAEDGNDAAQPKKLSLLVKDSSQPTDLSRTLMSQFGSAGYDVSLCSLQKPPVSPVDIVSLLDIDGPRSFFEDLDDRDLRGLIRFLTQHARGQQLLWLTGPAQIATANPHHAMVLGFARTVRLELGAAFATMELDDFAVGEQDQPSWTSAVVGVFDKIRKQEKHVVADCEYALVNGRVQVPRYVTRKADRVVSIPDDQALRKLRLAKPGLLASLEWEGGTRDSHLREGELEIAVRASSITHHDYLLASGAVHENRGLGFECAGTVSRVVAKGTNSAGFEVGDRVLCWSAGSLATHTRADARCCIKLPDGLSYNEAVTMATAYATATKALLDHGSLAMGDSVLIHSAATPMGLAAIQIAKMQGAEIFVTAGNEAETEFLVHDQNIPATHVLSSRDNSFVTGVMQATRSRGVDVVVNRLAGDLLHESWKCVAEGGNMIELSGRDGTGHGKLDMAMFGGNRGFHGVDITALIAQKPSLAPRLLERVMKLYTDGCIKPIGPINRFEYADIKQAFHQFHGDGPIGAVVVEFPDHPHSLPADSFNNDEVRFRGDRSYVLVGGLGGLGRSAAVWLAERGAGSIVFLSRSAPPSAERQALEQELKALGSDTQIMTGSVADAAAVERLAANAAKPIAGVLHLALVLKVSTYVQMTRKKEIERMAILNVYQLQDEALLDMTFDSWKAATEAKVAGTWNLHRALEGQPLDFFVLASSIYGVQGNPKQANYAAASTFLDAFVQFRQKRGLPASVIDLGVMQDVGYVSQHPAILENLRRAGAQLLSENDFLRSLQLSIRASSAPAPRAQFVVGLGQHAPDARGLGLKKKANGGNHPGTTGKKGASAQAGAEEEDDGDMLQQFLERAKRDASSLSDDQAQAAQFLATQVAECLKGLLIFGDSSNLDLKLGLADLGVDSLVAIELQSWWIQSFGTHITILELTKSASIMELGELARGRLLGALHGEDGQDLDGQQPAAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT34</accession>
    <name>A0ABR1VT34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665370.1">
        <property type="nucleotide sequence ID" value="XM_066813408.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046468"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38886:SF1">
        <property type="entry name" value="NACHT-NTPASE AND P-LOOP NTPASES N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38886">
        <property type="entry name" value="SESA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="240"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="572" mass="65587" checksum="BE23A4117D97F2BF" modified="2025-10-08" version="1">MSASFSFGSFGDIITTAQLVWRLAQALSDSRGSAPEFRELVKDLYLFYGALNELTKFWQSRAQTAELQRLAAELQHVSDDCHRTIESFLEKGLQRYGKSFLKPKTSPNSLSDRLKRIRWATLEKEEVTKMRDRLRRSKDTVDLIHSVAQSYAEDQNSVLVTTRLADLEDAERLVSARMEESFVTIVGALRRQEATISRMDDTIAAIRFESQSAFERLSHIEHNTALLPGINAGISMYSQNHAFIEDALGYKFPVPLLINPSWETVHSMIKDMFKNRPGMEMVLQRDYVLQDPNTRGDMQLSVEFHSSVRPGQKLIMAMVFRGSADSSLKGARSGDNICPKCRLSSMHLDPTGLDKFCKNRDCGFSYREIVDMSDASHDELKSWLERRDAKPNEYGDVQTYAASDFNTFEDFHHTLYRRESIESPEIFKRVRFLSRWEDRGDSRGGLKPFNFEGIHFWAFSDNGWIPEIKFQLRAMTWRHLTHSESIKVAVSKNSDPEHKKHVAFGLFFAGYNATVSIPVIKIISEEPLLREYALAALRKLEVVKSSRIGVLAFHPLTLWPDGDWEQTRQDCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU93</accession>
    <name>A0ABR1VU93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665753.1">
        <property type="nucleotide sequence ID" value="XM_066813791.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046851"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018465">
        <property type="entry name" value="Scm3/HJURP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10384">
        <property type="entry name" value="Scm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="599"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="790"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="836"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="925" mass="100418" checksum="B12CE84D41636F4C" modified="2025-10-08" version="1">MEPPAKRHKVGQPPPRDDPHNEANDDELTLSTSWIRAEQRPSSSSSPASIRKGLRWRGDEINLHTGEVIINNGHLQSLEDEQDKEDLSADEEEEERILQNKNPSSTSTSFTSGHSTPNNAALQLQSNWFSRLIDNTSAPLWDAAPFAAFGPAPVDPMWQTPELQMGGPQGHLGLFGNAYLGQMNPFQSGYGGGIGRLLNRGVPRRIATAAELAVRSRQDAFLGEELAEEEGSDENGLSGVSKEGGRPKQLPLDSSKQKAQERNSIPSATTSKGYFPKDDPIKKGGATTTENVLSESIRKPRASDKTLVEDVTSAGSLESQAQQEEHSVSRNKAVQPVEITDDSHAPKHSSSFVIELQSAPGGVIPQKQLIAKKIRREERSQGVEEDITEGSQGRRSGRPRVKPEFYGNVSWLKTRRPKPDMETLLDSDPNGEDHTPFEESEDLPDVDMAFADAPNYENPMTEEAILDTSEDLQPGDVGNKAFIEAAESIFLSRSNDATESPELAPESIFDRPSELQLPAPVGSEPTKAIQQGESFFRNHIDPSYNFSDDEDEFDGPELPKSPAEGLGLASHNCNNGIVTVPEAEESIEIPAIQDEEVQPVESPSTTTTVETSKFSRIPVSEANHGETDEENAQTTSPEILVDRTAIAADSASDRGASLREQERDSSGHTAAQEVLHDSSPPPGPELPPSPSLSRSIAKPRRPLAKPAAASPRTPKKKTKKRSLNDDSASGQGDKTKTTKSTATTSETKRLTSSAKRHALASLIPDNSDDEDEISILAHTPTSSRHAEAPFSSSPLRNNTGEPFTPSHRGARNRSSLGSSVAAARRTESRYAPATDSRALAGHSSSAARRRSSKADYRSTAAKTKTTAFSSPLLQRVLKTPRTVRRYHHPSFTEEEGLVRTPGGTMRRCGVDGFVCDRDFCLTCCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUX7</accession>
    <name>A0ABR1VUX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009723</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666000.1">
        <property type="nucleotide sequence ID" value="XM_066814038.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047098"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13866">
        <property type="entry name" value="CuRO_2_BOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13889">
        <property type="entry name" value="CuRO_3_BOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48267:SF1">
        <property type="entry name" value="BILIRUBIN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48267">
        <property type="entry name" value="CUPREDOXIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047048932" evidence="4">
        <location>
            <begin position="22"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="70"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="370"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="561"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="561"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="595" mass="67024" checksum="9B600789B97E767C" modified="2025-10-08" version="1">MAFSTLIRLTAALSVLGTTLAKDWESPEYKWLYQYPLPIPQTKALNRTIPHPVTGKDINYYEVEIKELKQQVYPDRGPATLVGYDGLAPGPTFQMQRGTEAVVRFINKSKNPNSVHLHGSYSRAPFDGWAEDVTKPGEYKDYYYPNGQNARTLWYHDHAIDITAVNAYYGQAGVYVLHDGEESALNLPSGNYDVPLVLSSKQYNNDGSLFSPASETTSLYGDVIHVNGQPWPYFKVEPRKYRFRFLDASISRTFQLYFESDKKLGEKQDFNVIASDAGLLSAPQKVKDLYISMAERYEVVMDFSKFKGENVTLRNSRKIAADIDYLHTDKVMKFVVGKDSVEDNSVLPSSLRSIPYPQDRTTIDHEFLFERKNGGWRINGVSFADTANRVLAKPPRGKVETWKLVNGGGGWSHPIHIHLVDFKVVSRKNGRNAVMPYEAAGLKDVVWLGPNEEVVVEANYAPWDGLYMFHCHNLIHEDHEMMAAFNVTFLADLGYNETHYLDPMDPEYRAKAIKPEAFTDDAIRKRIQFMASFQPYNKVDETEAVLDAYWATKGSRAVAAAATTGSSPTKTTTTAAATTTPGKRGRGRRGRSELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUY2</accession>
    <name>A0ABR1VUY2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein fluG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009721</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665998.1">
        <property type="nucleotide sequence ID" value="XM_066814036.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047096"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF2">
        <property type="entry name" value="TYPE-1 GLUTAMINE SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="5">
        <location>
            <begin position="116"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="254"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8075058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="52678" checksum="EC11B6E4825DD7EA" modified="2025-10-08" version="1">MAEKQSPDEILTRLRSLDAKWLRIYWVDATASSKCRLVPMKRVCKTLESGKPLTISILQGALGLLPCDILAPGVSATHTYNLHPDWSSLRRGPVEGHASCYGEFRQIDGSGCVLCPRRLLRKTVEQAAASGLDFLIGFEIEFVALEKVPRNDQAAAAEGDGDAPKYRTISHDGHAWSTSRALAEWGRQDSIVTVLDEMVDLLDAADIPVEQLHAESTPGQFEIVLPPLPPLQACDTLLHARQIIESTAARHGFRVTLHPKPSPGLPGTAAHAHMSVLKSSSSRSEASSPQEEEEEEEEEEEAETEVYESFYAGILAHLPALAAFTYANPASYERAVDSAWAGGRWVAWGTQNRETPLRKCAGSHWEFKALDGLANPFVAVSALLAAGADGVARATPLAATWKDCEPDPASLGPEQRAALGITRELPRDLDQALGFLAADETLEGLVGREFVRRYVDVKRAELAFLMPMADDERRQWLVERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW80</accession>
    <name>A0ABR1VW80_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666460.1">
        <property type="nucleotide sequence ID" value="XM_066814498.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047558"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="63753" checksum="19A1AD43BF33E47C" modified="2025-10-08" version="1">MPPGSHATKIGLRVTAQTPGHGRTSHPGGFVRFLRDHWVIAGAFMFGLSFCLGVFGYINTLSNQAFSCPPWAVNCDLTGPVKFLLANNSLLQGALTTGYSIGLAAMGFSICSLGEAALWPLWHRRAYKLRHIDTYLAASRGSLISLAKALITARCPQAIMVVVCIFVSAALQPAGPTFVGFALARTNVTTVYQSNQTVGGGMGLGFEQQKLAPARLPGAISDAIALYTAWAKSLAVEPLPDQRDYILDRDMLSPVGNASVFAVRANRTIDCLPRRVDLVDTGLGYYRVNTTLPPDNSVSIRVTPALNAWVEKITIQSPTRVISTLVFANLNGRIEGGENVVIESQPSWSGVSGVVCTVDTTLWDAHVNIGNAKTPPRMISSLDSIKSPMDNTRLDEVVTWISVAPTLMGMSVQGTQPTFRKSEMGLPQSWTTQPTMPEDTDSSNFTRKELEDFIAVSGGAICTCIPGKFAPVSQSGFHYDAFVTLDSEYFDAHIDPTRTLILLVPVFIITIAGIILTAFNAAEYRRHRIPYMRLATVGELIKSAQTEHIREKVGAEESGDVNTYRKIDELHLRFGVCSDGVIGLGETVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX00</accession>
    <name>A0ABR1VX00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666731.1">
        <property type="nucleotide sequence ID" value="XM_066814769.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047829"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43611">
        <property type="entry name" value="ALPHA-D-GLUCOSE 1-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43611:SF3">
        <property type="entry name" value="FLAVIN MONONUCLEOTIDE HYDROLASE 1, CHLOROPLATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="557" mass="62188" checksum="AD3BC7CCFCBF9451" modified="2025-10-08" version="1">MGPPLILKNPLPCTTLILDLVDVLCFCSIEDLEDLPISPPMLQYILNSRDWHLLESGIIDRKTCFEDLSEKLYDVEERDLTWTLRRLKGTLTYNDKLLETVGALKEAASTSSSGYGHGHGKKLRVVLAANVGREDWEQHLRDEVEGWDLFDAVFLSHWVRARKPAEEFYRYVLRELGLLLGEGAAAATVATSVACVEARPEHCAAAAAWGMHVIPFGTTEGCVADLVELFGDPVARGEAWLRRHAREMWSTSSTGVLLKEQHSQLLLKELLDWSYVTLAGGEQEQWNVFIDEPLLTTPTYPDDLGTTALGLKNVGVGSEKIKHRVLDRFLDHLRGDGLFETYFDDKDRPRVDHVTTANILRLFYFHGRSHELRRTLQAVTDIARTRAYAFGTRYHMHPDWFFYYLSDLCRLSFPCCAPGRELAALRSLLRERLAERFGGGSGAGRRPLGQRRAGRELAPRRRADGNVPRDVETVKRAQQRDGAWSADPWVFRYGSGVLIQNAGLVTAFAVKALRVSGACRSVLNRCSLPPPPAAPSRAAVVPEIVISSPGGSKSRCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX89</accession>
    <name>A0ABR1VX89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666789.1">
        <property type="nucleotide sequence ID" value="XM_066814827.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047887"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42354">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42354:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="42760" checksum="D860CDACC0993FB2" modified="2025-10-08" version="1">MDLDTVGDLVTALVSTYDDGLECYTRWQRKQGQANHYRGHSRRGQVSDSGSCGLSTSLMVSASRLRQVYDSGVDVLGDTFSTGDSKTHRHHQQCRGSLQASLEMLQAHVEALHSAARRDNAPLGLFEMIRASEAARISSLRALAEQYQRVAVGRLVPSELPIRQPPPRRPSAEPSSPVEIDAETDFAPELAGYDDGAEGRIWNDGCRRHEQHAIPPPCQIATVSATDAQGDSPDDLQSTCTSEFGPRPRASVFSVFCPEAMKYQVDLQKATPLSSSSSSLSAFHRKRDTCCSQCGYRWNGNGNDGGDSRDPMSSSNNRKKAAFATTIKDGFQLTPRFLGKSHCGTGGFGCVLCTSSGRTDVYESVERLRDHINASHDKWQMLHERDMVNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7D2</accession>
    <name>A0ABR1W7D2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666869.1">
        <property type="nucleotide sequence ID" value="XM_066811527.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044587"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="253"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="364" mass="40709" checksum="ED9CA141830E80D1" modified="2025-10-08" version="1">MDSKATIQDEAVIYVALKDVLNGILAQIRQSKAIRRAISLNSKVKKVADLLKTHQEQVIVDTTRHLLSEEIFASTEKAKLRFLWLFKSLSFLKAERTASSEEAVQGKRSSLSTERIFSDGETAVACIDTAMASQSWKPIQASAMAKQLFPVHLPFRAQHQLLVHLQQLLELSAAASLGLRRSGGAQPVGSGPVQEIDEPEREKEREAAGTAFASITNIRHTAVHRNRISAAALEDFFRDAEAFTALLGDTKTTETIARMRQEIKTTIEELERNTKAVHSKLDRTMHEIGAKREELRRLEKEALDDVQRENGECQGMAARSIDTVIAPPKPLSETAPVVENDMVVEDETTINKGFDYMLMDEYWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7P2</accession>
    <name>A0ABR1W7P2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007312</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666969.1">
        <property type="nucleotide sequence ID" value="XM_066811627.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044687"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF28">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="56554" checksum="E49CEF766CA288EC" modified="2025-10-08" version="1">MGQLEKKGSPLADAQSDIKSGQTEEHGIHDQFNLNALGYKPELRRNRSMFTLLFQSLAIAAIPYGFGAPLISAVYGGGQLAMFLGWVMILIVDECIAISLGELASKYPTSAGPYYWSFQVASPRYRTLLSFITGWTWLVGNWTITLSVNFGFASLLAATVALYYPGFEWQSWHLLLIFYAICIITFFIVAFGNRFLPAVDTFCAAFTAITIFITLVCLSTKADSGRHSPGDTLGYYDPTLSGWGDFSFLIGTLPSAYTFSAIGMITSMAEECGDPTTKLPKALSLSVPVGGIAGLFFIIPICATLPALTDILEAPLGQALPYIFLRVMGSQGGALALTVLILVITLFCSISITVAASRCTWAFARDKAIPLSRVWSIIDKRHETPIWALILTTIVQMLLGLIYLGSSTAFNAFVSVGVMALAVSYGIPIFLSMINGRRGVNTASWTVGRTIGWVVNCVALAWICFEVILFSMPTAIPVDGATMNYAIVVFVGFMTLSAIWYLVHARKVYSGPPESDGLAAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8I8</accession>
    <name>A0ABR1W8I8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007617</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FKBP-type PPIase family. FKBP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 6"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667274.1">
        <property type="nucleotide sequence ID" value="XM_066811932.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044992"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="19"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="144" mass="15421" checksum="64E0EE8E05E01BC4" modified="2025-10-08" version="1">MGVTKTTIKEGSGAIPQVGQSVTIEYTGWLKDTSKPDSKGNKYALPLLPSTRLLFTVLAMTMTFDSSVGRGDFETTIGVGQVIKGSSANRSPFIGWDEGVTQMKVGEKATLTISSDFAYGSRGFPGHIPPNSDLIFDVELKKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W954</accession>
    <name>A0ABR1W954_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="14">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_007858</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="14"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667515.1">
        <property type="nucleotide sequence ID" value="XM_066812173.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045233"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF346">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 14" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="401"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="445"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="880"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="907"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="951"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="986"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1025"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1056"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="138"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8080040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1161" mass="125854" checksum="640402996D656973" modified="2025-10-08" version="1">MASRQHTLAPPTLQVNTRLGPNNDVEDERTPSRQSTVSNPFLSPTPTNTNPFLTPSNRSRASSVATTLKPEDALRPDPGTEGDFIVENNPFAFSPGHLNKLIDPKSLQVFKALGGLRGIEQGLQTDIHTGLSVDEKSPRQRITLEEATQNIKHEASTEYNGASPEAFSDRVRVYGKNVLPAKKATSLWRLMWNAYNDKVILVLTGAAVISLSLGLYETFGRPHPPGSPPPVDWVEGVAICIAIIIVTVVGSLNDWQKERAFVKLNEKKEDREIKVIRSGRSYMINVHDVLVGDVLHLEPGDLIPVDGIFIGGHDLKCDESSITGESDAIKKTGGQQVMDILESGRPAHNLDPFIISGAKVLEGVGTFVCTSVGVHSSFGKIMMSVRTDIESTPLQAKLERLAVAIAKLGTGAAVFLFFILFFRFLAGLPTNNKIPAEKAAEFTDILIVAITIVVVAVPEGLPLAVTLALAFATKRLLKENNLVRVLRSCETMGNATTICTDKTGTLTTNKMTVVAGTFGSTSFDKPDNKGPETQTVSQWASGLTAATKEAIIQSVTINSTAFEGDEDGQSTFIGSKTETALLTLAKEHLGMQSLSQARADEQVVQMMPFDSSKKCMGAVVKRHTGEYRLLIKGASEILLECCTSKVVTTNLASSELTTSVLSESDIGVLSNTINTYARKSLRTISLVYRDFSQWPPAEITSIDGYVDLASVLNNLVFLGLVGIQDPVRPGVPEAVKKAQFAGVVVRMVTGDNVVTAQAIAAECGIYTDGIIMEGPVFRRLNDEEMDQTLPRLQVLARSSPEDKRILVMRLKERGETVAVTGDGTNDAPALKAADVGFSMGISGTEVAKEASSIVLMDDNFASIIVALKWGRAVNDAVQKFLQFQITVNITAVLLAFISSVSDPEMKSVLTAVQLLWLNLIMDTFAALALATDPPTEKILDRPPQPKSAPLITVNMWKMIIGQAIFQLATTLILHYAGRQILNYSDLVVDTMVFNTFVWMQIFNEFNNRRLDNKFNIFEGVHRNKFFIGINCVMVGAQIAIIFVGGAAFSITSINGTQWAICLLLAVISLPWAVVVRLCPDIWYEKVAGVVGRPVVVVYRALGSVFSRIGQMLRGLKREKATATEGDVEAPRDSQPPMVVVSEGAIPSIQIGSASDDERGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9K0</accession>
    <name>A0ABR1W9K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deoxyribonuclease NucA/NucB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007987</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667644.1">
        <property type="nucleotide sequence ID" value="XM_066812302.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045362"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029476">
        <property type="entry name" value="DNase_NucA_NucB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14040">
        <property type="entry name" value="DNase_NucA_NucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047285700" description="Deoxyribonuclease NucA/NucB domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Deoxyribonuclease NucA/NucB" evidence="3">
        <location>
            <begin position="36"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="274" mass="29323" checksum="C6935BE178D0F61A" modified="2025-10-08" version="1">MHTTTVALLVLAASAATAKGIVYDCSKTPQICLNTCWAVKCAGLPAGLHGGGNKDAKASKKKGTENRNAWGYGSKPCDESKHNKYWKNGNVKNTSPDEYPYASSKEGGLKGAGKPVQLRCVPTAEQKSQSGKVSGLGTAKTTDVWTTKWDNIQNLPQDWCGAAPKCKNDGHQFTATAKGVFTRSLDIGAEHIPVFEDAVYEGNSTTINVRADEADLGDVDDVPDVEEEFDDGVEARDVEEADLDIDDVPDVEEDEDEAEGVEARGEKVGLAFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9N3</accession>
    <name>A0ABR1W9N3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial outer membrane protein OM14 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667222.1">
        <property type="nucleotide sequence ID" value="XM_066811880.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044940"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039454">
        <property type="entry name" value="OM14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38402">
        <property type="entry name" value="MITOCHONDRIAL OUTER MEMBRANE PROTEIN OM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38402:SF1">
        <property type="entry name" value="MITOCHONDRIAL OUTER MEMBRANE PROTEIN OM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="21493" checksum="5F5BAB21EB482B7E" modified="2025-10-08" version="1">MSSSFSVARMDGSTRSKEQGAKSKEQDKHGRLATPNTANITMSYADIAASGPKQTPEEAAAPQPPEIVPTESASTSSLVDVDTPDIQTETQAARRDREEEQRRAEADLAKKKAAGKARRADSFLTKWFGDMNDGASTALVISNLVGVVGLSGFLGYKAWDLHARNRLSWQSVGLGLGIMGVVGAVEGVFGRYLYKGKKSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAH5</accession>
    <name>A0ABR1WAH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667989.1">
        <property type="nucleotide sequence ID" value="XM_066812647.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045707"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="270" mass="29389" checksum="C9BBDB374D3A5EC2" modified="2025-10-08" version="1">MDGFGTEASNDVVNSGRACRLSLNPTKEPRKRPLELSTYSLCVPTSIATAPFALPGPKGIRKTHRPDGHHGGRANIPPVADPDRSDRRPGRALPVLLLAHARVPAATPRCRLRRPDPRGRRRAHTADVPQLDRRTILWDLQRTGGSISATTERVLSGRIETPPVTFQPPSPPRTPANAASATTRSQQQKPAIPKSTEPDLITRYNLQSRINDSPGSAENGGSVDAKGKAWSSNRDERQSALQRRRDEMIIAARRKMEAKIAAERAGAGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAZ3</accession>
    <name>A0ABR1WAZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-type alcohol dehydrogenase-like protein YycR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668146.1">
        <property type="nucleotide sequence ID" value="XM_066812804.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045864"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF3">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="26"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="392" mass="41496" checksum="A7C0F0315F62992C" modified="2025-10-08" version="1">MSTTTTSTAAGGKGQNTYLTVRKIDGNPGKVYYPLQLHTAPIPAPGPGEVLVELHAAALNHRDLFIRQHLYPGISFAHPLLADGCGTVIGYGRGTESDFPSLLNRRVLLMPTRGWYQSRDGPEDLKKYTVIGGSQGDPAGAAQRYIALPAAEVEPLPAHLTSVEGAALPLVGVTAWRALVTKCFDGDLARAPGRNILVTGIGGGVALQLLQFGVALGCNVYVTSGDPAKLARATGPDLGAKGGVNYRDKDWDAQLGKLLPADRPYLDAVVDGAGGDLVARTVRLLKPGGVLACYGMTLSPNMNWSMGAVMKNVELRGSTMGSRAEFAAMVEFVRAHKVRPVVSRVIRSGGLEDLDAIDGLYEDMRQGKQFGKLVIEISPERGQNDSSVAAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBG4</accession>
    <name>A0ABR1WBG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666994.1">
        <property type="nucleotide sequence ID" value="XM_066811652.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044712"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045123645" evidence="1">
        <location>
            <begin position="17"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="73" mass="7769" checksum="882D5C2AD10E2EBB" modified="2025-10-08" version="1">MQFPFFLALAATAVLAMPSNNLEARHECTPPSYACKGDKSGWLVCNVDGSWLNGGSCPKGTTCSPINNLPYCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBX2</accession>
    <name>A0ABR1WBX2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Non-canonical non-ribosomal peptide synthetase FUB8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668397.1">
        <property type="nucleotide sequence ID" value="XM_066813055.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046115"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="3">
        <location>
            <begin position="552"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1055" mass="116718" checksum="893F6B7E517461DA" modified="2025-10-08" version="1">MASDSSPHIVDANAVEKPDAEWISIPNSSNPKDGWRVITWKEFGNAVNACCHRIIAKLGEAPKNEFPTITYIGANDARYFVLMLAAVKTGYKCLFVSPRNTMEGQLNLFDKTDCHMLAYSESHRTMVQPWLEKRHMHSLEVASYDDWFPKEDVPVFHWSKTWEEGRWEPLCVLHTSGSTGLPKPIVCKHGLLAVGDAFHNCPEWQGTDTFLKQFNVLMNRQFHPMPLFHAAGLYIGSLNSIYWETPVALGIPDRPLTSELAKECLANAGVQGTLLPPAIVEEMSQSQECIDVMKKMSFIGWGGGQLPREAGNRLVQNGVFLANLIAATECCPFPIYWNKDPNNWQYFIYNSEMFGCEWRKQEGQEDIYEQVIVRKAEDPGMQGYFYTFPEEKEVSTKDLYRPHPTLPNHWIYYGRADNIIVFSNGEKLNPVDIEDIVSDHAQLKGAVVVGANRFQAGLILEPYTHPRNDEERKALLDSVWPLVEQANADTVAHGRIGRDFITFSSPDKPFERAGKGTIQRAATVKMYTEEIEKLYEQAGKAAAANAPALDVSSVDGLTQSIVELFSAKQGAATLGPDADFFSSGIDSMQVIGASRLLRAGLEAAGYKPEPKALLPRVIYNNPTPKKLAAYVMQTILGNASSEPQSANSPQAMEALWKKYTENLPAPAHPGRPEANTTGQVVILTGSTGMLGSYMLEAMAADPKVARVVCLNRAEDGGVAQQARSMRERGLDEGYHGGKAEFYRADVSRPDLGLSPAVYEALARDVDRMILNAWPVNFNMPVESFEPHLAGVRYFGDLAARAAKRAAVVFISSIGSIQGWSMNERGRPLPEERFEDWSLPSGGYGCSKLVGGLIIEDAGKKGDFPTAVIRVGQIAGSDRGSGVWNRHEWLPSIVHSSLYLKALPEHLGSFNRVDWTPAERIAGLVVEVGGITVEKSPQNISGYYHGVNPKVTTWSGELAAAVREYYGAEKLPETIPFKEWIARLEQSAQAAPEEVATKNPGAKLVDSYREMATAEDHGLRPVELETQRTVGQSPTMAKSDAVTPELMKQWCEQWAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC31</accession>
    <name>A0ABR1WC31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668531.1">
        <property type="nucleotide sequence ID" value="XM_066813189.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046249"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="133" mass="14503" checksum="6E1419CDA019C3D9" modified="2025-10-08" version="1">MDNKNPGGCKPQLLWLETKEETASTGHFEPELARLLEVPGGHPLPRQRPPDRPRQPPARPATVPRLVAPPPVRDRARRQTTAVKVNQTLHGGAPVPSASTAWERHLLKGPPSSPTSNHHPAPPALSTPPKWPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCH0</accession>
    <name>A0ABR1WCH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009027</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668684.1">
        <property type="nucleotide sequence ID" value="XM_066813342.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046402"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039577">
        <property type="entry name" value="Rad18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8081209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="103" mass="11010" checksum="48B750B525B24115" modified="2025-10-08" version="1">MLTSCNHTFCSTCIRRALASDAKCSLCRSVQEVSKLRSNWSMEEAVLAFVKTRADLLALARKPPTVLVHTVEVPVAASTSASPKHALDAEGETPPQMTSPPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDA3</accession>
    <name>A0ABR1WDA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008810</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668467.1">
        <property type="nucleotide sequence ID" value="XM_066813125.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046185"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="38"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="51600" checksum="C17A51C1AB81221E" modified="2025-10-08" version="1">MADILSPSSLKALADVEILLPADPLYGIRERSYHAANARLAPSCIARPTSAPQVASLLRELAASKTEFAVRGGGHSPVPGASDIASGGVTVELGLLNKVTYDAAGETVRFGAGARWRDVYGELAKYQRAVPGGRSGGVGVSGLLLGGGSSWQVAKHGWACDNVMSFEVVLGDGRIVTADKDTHADLFRALKGGANNFGIATSFVNRTHSSDRIWGGIAANPESATGQILRAVRNFTQRQGQGEARDSYLMAVFGYFPDFGANVGSTAVFQAGSNPSGPEFEEWRALPKIVDMTKETTMAALAEEITLPANYHDAWFTLCIKNDEKIMKKATDAHETLVAELKSYISDGNFITNCIFQPVPRTVSQRTAAAGGNIMGTERIAEDAVLFQLAVMTETAEQARWAHPKLQRCVDALRDFAAEKEVEGGGGLMDWVYMNYADASQDVIGSYGAENVEKMRRVAVKYDPELVFQKLCPGGWKIPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDW5</accession>
    <name>A0ABR1WDW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">IES6 INO80 chromatin remodeling complex subunit 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008463</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668120.1">
        <property type="nucleotide sequence ID" value="XM_066812778.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045838"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029525">
        <property type="entry name" value="INO80C/Ies6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200:SF1">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="6">
        <location>
            <begin position="148"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="29"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="199" mass="21355" checksum="84D06F2BA2692E58" modified="2025-10-08" version="1">MAAPTEAQIAHQELIDKLDIHSVHRTFRNPSWKPNSRRNKNVKTILGDASRKETSIMATPQDDSGPATPANGDNDGLSTSGTTTPAPSTDGTSLQQPNLAQASRSLSKLVLEKTLRPNGGATGGATANAPSATYTNIESAPSLAHTKRYCDITGLPAPYLDPKSRLRYHDKEVFGFIRSLPQGVPEQYLEARGAHTVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDY6</accession>
    <name>A0ABR1WDY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fatty acid synthase subunit alpha</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
            <ecNumber evidence="4">2.3.1.41</ecNumber>
            <ecNumber evidence="2">2.3.1.86</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">PG997_008207</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="27 28">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 4n H(+) = a long-chain-acyl-CoA + n CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.86"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 22">Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EC" id="2.3.1.41" evidence="4"/>
    <dbReference type="EC" id="2.3.1.86" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667864.1">
        <property type="nucleotide sequence ID" value="XM_066812522.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045582"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00828">
        <property type="entry name" value="elong_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08950">
        <property type="entry name" value="KR_fFAS_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040899">
        <property type="entry name" value="Fas_alpha_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047224">
        <property type="entry name" value="FAS_alpha_su_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026025">
        <property type="entry name" value="FAS_alpha_yeast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041550">
        <property type="entry name" value="FASI_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050830">
        <property type="entry name" value="Fungal_FAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982:SF21">
        <property type="entry name" value="FATTY ACID SYNTHASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982">
        <property type="entry name" value="MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18325">
        <property type="entry name" value="Fas_alpha_ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18314">
        <property type="entry name" value="FAS_I_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000454">
        <property type="entry name" value="FAS_yeast_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="23" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="17" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 22" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 22" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="25">
        <location>
            <begin position="141"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="26">
        <location>
            <begin position="1081"/>
            <end position="1621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="23">
        <location>
            <begin position="534"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="24">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRNR" id="PIRNR000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAK8080389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1854" mass="203742" checksum="EFDE2D3D9D67EBC5" modified="2025-10-08" version="1">MRPEVEQELAHTLLVELLAYQFASPVRWIETQDVFLAEKTAERIVEVGPADTLGVMAKRTLASKYEAFDAAKSVQRQILCYNKDAKEIYYDVDPIEEEPEPAAESSSSSGGAAPAAASSSAAPAAAAPAPASAGPAASVPDAPVQALDIVRALIAQKLKKPFLEIPLSKAIKDLVSGKSTLQNEILGDLGKEFGSTPEKPEDTPLDELGAVMQATFNGQLGKQSLALIARLVSSKMPGGFNITSARKYLETRWGLGPGRQDGALLLAITMEPSARLGAENDAKAFLDDRPAPAAGGGGGMMMDLAAIDALTKDQRALFKQQLELLARYLKMDLRAGEKAAQVSQESSKVLQAQLDLWSAEHGDFYAAGIEPVFSPLKARTYDSAWNWARQDALHMFYDIIFGRLQVVDREIVSQCIRIMSKSNPLLLEFMQYHIDNCPTERGETYKLAKELGQQLIENCRDVLNVSPVYKDVAVPTGPRTTVDNHGNIKYEEVPRPSCRKLEHYVKQMADGGKLTEYGNRSRVQHDFTRLVKLIKAQQTMAKTAQTEIKSLTNNLRQSLAMNESQILPRENGKSAGLAKRSGMKATTAASTNKGKTETIPFLHLKSFDELTGWEYDRKLTKVFLDCLEVAAKDGVSYEGKYVLMTGAGAGSIGAEVLQGLISGGAKVIVTTSRFSREVTEYYQAMYAKFGARGSQLVVVPFNQGSKQDVEALVDYIYDTKKGLGWDLDYIVPFAAISEQGRQIDNIDSKSELAHRIMLTNLLRLLGCVKAQKIERGFETRPAQVVLPLSPNHGTFGSDGLYSESKLGLETLFNRWRSEDWASYLTICGAVIGWTRGTGLMSGNNVVAESVELEGARTFSQQEMAFNLLGLMSPQIVDLCQHQPVFADLNGGLQFLKKLNKLMGRERASITSTSEVRRAVTKETAIENKIVNGDESEALYKKKVIEPRANLKFDFPNLPDWKQDVAPLHDKLKGMVDLDKVVVVTGFAEVGPWGNSRTRWEMEAYGEFSLEGCVEMAWIMGLIKNHNGPVKGKQYSGWVDAKSGEPVDDKDIKQKYEKHILEHSGIRLIEPELFDGYDPNNKELLHEVVIEEDLEPFESSKETAEEFKRQHGDKAEIFEIPDSGEYIVRMRKGATLWIPKALRFDRLVAGQIPTGWDAKKYGVPEDIISQVDPVTLFVLVSVAEALLSSGITDPYEFYKYVHTSEVGNCIGSGMGGAGALRGMHRDRFLDKPVQNDILQESFINTMSAWVNMLLLSSSGPIKTPVGACATAVESVDIGYETIMEGKARVCLVGGFDDFGEEGSYEFANMKATSNAVDEFAHGRTPQEMSRPTTTTRNGFMESQGSGVQIIMTAQLALDMGVPIYGILALTTTASDKIGRSVPAPGQGVLTTARETARKFPSPLLDIEYRRRQIQQRKNQIQDRKEWEMQYIQQEVEAMKSAGEPFDEKEYLESRVQHIEKEAIREEKEALRSFGNNFWKQDTSIAPLRGALATWGLTIDDLDVASFHGTSTKANDKNESSVICQQLRHLGRKKGNAVLGIFQKYLTGHPKGAAGAWMMNGCLQVLNTGLVPGNRNADNVDPIMEQFDLIVYPSRSIQTDGVKAFSVTSFGFGQKGAQAIGIHPRYLYATLDEATYDAYCKKLAARQKKTYRHFHNGMINNSLFQAKAHAPYTEDQLSSVLLNPEARVSEDKKSAGLVFAADFAKKAAVAAQTSVSKSTTQALTETMARTLPMNKGQKHGVDVEDISAINIDNETFVERNFTEQEIAYCRKSPSPQSSFAGRWSAKEAVFKSLGVRSQGGGAALKDIEVLPNENGVPTVTLHGDAKSAAEKAGVKEVVVSISHTDLQAIAVSVASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WF93</accession>
    <name>A0ABR1WF93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mfs general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009004</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668661.1">
        <property type="nucleotide sequence ID" value="XM_066813319.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046379"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF19">
        <property type="entry name" value="DUF895 DOMAIN MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045476807" evidence="6">
        <location>
            <begin position="20"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8081186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="418" mass="45735" checksum="743EB39F9EBB2868" modified="2025-10-08" version="1">MYNMTILGLCNLLAPGLWTAMNSLGAGGAQSPQLVNAANAATFCLMVVSCYFSTAIVHYIGIKHALSLGTIGYAPYAAGLYLNNRYGVEWLVLLGAVLCGISAGLFWAVEAAIAIAYPEPWNKGRALGWWLTFRLLGQVLGGAINLGLNADRNDAGKVSYAVYLVFITLQALGLVVSLAIMDKPWREMKATAENFFRPQFLLILLWIGQAVFAEAVMFTYLALWFSVRARALGSFLGGVIGIIAGNAAGAWLDTTRLSVKTRGRYAFWFFTLASGAWWIWATVLVSRFRVTQPTYDWASPGFGRAFVVYILLNAMFQVNYLYLYFMVSHIANGEPEVLRFAALLRGTESAWQAVSYGLTSLTVFAQVGGVYFNLVLWAFSVYPAWLVVRGFGATAAKSRQLDHEAAQESASDKIDTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPD7</accession>
    <name>A0ABR1WPD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006681</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669919.1">
        <property type="nucleotide sequence ID" value="XM_066810996.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044056"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22147">
        <property type="entry name" value="F-box_SpPof1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="462"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="716"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="819"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="859"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="901"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="941"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="552"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="287"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="563"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1047" mass="116265" checksum="55F36DBE2997B430" modified="2025-10-08" version="1">MEPQQAVASSSTQQSARSRPRSSQTTISMNWDDGDSLSPRPRMKFEVAECIETKTITTTTTTKRSYPPLFVREPRSLATLDSKEYPLAQKPTPPELAKFSFDLDKYGALSWPGADEQGQQHESFQSTGTTSGDEQMQDEIKTEPGLDISQTRRRSSKAPMELATRRSHKMGTRSASPIVSGSVRKKSQKPVARSQGPSLSTAVSDKLRRTLANGPRRDGDRELGTAVRPASGFPVTPDTTELAGPTASQEYPERPHRLGRSHLDSFETPESDPSQAHQHEYFDISSPAGSDTHTVFSSNVATPPITDADPEPLTDADETLQQSIRALQHPRPINTLAAQDASLPSPRLSPTLQAAQLHTADPQDEGDEESMSVVVHEDSQDIADEEYDHPSALAEFRSQMLNSQHASSHAIQSGIMDSRLMLESFDAMPAEMKSFMIYQFLRRCPRKTLHVVADVVGPALKCDILKDLPGELTLHIISYLDAQDRCRASQVSKTWRSIIDSDETGWKELFDRDGFTLPPGELDRAVREGWGWQDPVGPEGCERDFSLQKRMASSEAELRSSSKADASSPSQAKSSRTTKRKRLGFHNISDRTTKRRISDNFMKKEKEEPQQASPKMHKSEGPISAANAAALAVPDPHIGLLSLRKLHLFKSLYRRHYMIRKSWTSGKVKPSHVAFPAHPRHVITCLQFDEDKIITGSDDQLIHVYDTQTGKLRKRLEGHEGGVWALQYEGNTLVSGSTDRSVRVWDIEKGLCSQILMPKDTGKVQDGAPVMMPPKPLIITGSRDSQLRVWRLPEAGSRRYIQTGPPANDADCPYFIRTLQGHTHSVRAIAAHADTLVSGSYDNTVRVWRISTGETVHVLQGHSQKVYSVVLDTERNRCISGSMDSFVKIWDLETGSCLHTLEGHSLLVGLLDLRDERLVSAAADSTLRIWDPVTGRCQSTLTAHTGAITCFQHDGRKVISGSDRTLKMWDIKSGECIQDLLTDLSGVWQVRFDERRCVAAVQRNQLTYVEILDFGAVRDGKNPAELGKRIVLQSNELAREAEAEDNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPH8</accession>
    <name>A0ABR1WPH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Opioid growth factor receptor (OGFr) conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006721</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the opioid growth factor receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669959.1">
        <property type="nucleotide sequence ID" value="XM_066811036.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044096"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006757">
        <property type="entry name" value="OGF_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039574">
        <property type="entry name" value="OGFr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14015:SF2">
        <property type="entry name" value="OPIOID GROWTH FACTOR RECEPTOR (OGFR) CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14015">
        <property type="entry name" value="OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04664">
        <property type="entry name" value="OGFr_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Opioid growth factor receptor (OGFr) conserved" evidence="3">
        <location>
            <begin position="41"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="227" mass="26548" checksum="64E8CDAF54DD4FEF" modified="2025-10-08" version="1">MSPPRPTNQAMQRLVDFYDPSVMGTDVGDRTLSQILAWRDTRLESQHDYIQILFPLPEGSLFNEYSPVVDEEAFLYLRHDANAGFKRTMRRALARMLSFYGFDITWDQDAAGQWAVAVTAKPSAEQDHFPRWVRRMDHNHLRITRILRSLRVLGLEDEARAFFAALCWTFDAYRRIGDGSMKFWRRAMELPLHVAPDGTEVDWLEKYEEKEETEKTEETKDERPTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQP8</accession>
    <name>A0ABR1WQP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">General negative regulator of transcription subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_006071</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669309.1">
        <property type="nucleotide sequence ID" value="XM_066810386.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043446"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012270">
        <property type="entry name" value="CCR4-NOT_su3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007207">
        <property type="entry name" value="Not_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04065">
        <property type="entry name" value="Not3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005290">
        <property type="entry name" value="NOT_su_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-Not complex component Not N-terminal" evidence="13">
        <location>
            <begin position="3"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="14">
        <location>
            <begin position="498"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="237"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="287"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="347"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="424"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="498"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="306"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="359"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="392"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8084800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="629" mass="70169" checksum="13C111A5A8E7DDEE" modified="2025-10-08" version="1">MAARKLQQEVDKCFKKVAEGVAEFEAIYEKIEQSNNPAQKEKLEDNLKREIKKLQRLRDQIKTWAASNDIKDKAPLLEHRKLIETQMERFKAVEKAMKTKAYSKEGLSAQAKLDPKEQAKVESSEFLAGMVDELEQQIEALEAESESIHATMKKGKVNTVKADRIASIEHIIERHKWHQAKMELIRRSLENGGVESEQVTDLEESIRYYVSDGMNDDFVEDEELYDELQLQEDEDIFGINPDNDRVSSQDTQSIQDEAPESEPRPSSLPGKPARTAVDAVVAAGRRPSAQLKSPLPTLATLHNPLSTVTNGSSTTVGMKPASLPTRPAGEGLKYASAAAAAADKNNLGIAPLPPPPGSQPVVPSTGVSPLPGVRTSATSSPSIASIQPATSESRPSAPSSITDSRISEPIPAVAAVAKKEKAAAKAAGKSPVPPASLSKAPQTNGASNGVKPNDQDDEEESIYHLPASLSDLLDSFNVTRKRELPVSSQAHLRMMHASQTNTPDLADADAPRKYRPEHRHSSLSQYPQEPLAIFDDPRLYSRIDPDTLFYVFYYKQGTYQQYLAAKALKDQSWRFHKQYQTWFQRHEEPKSITEEFEQGTYRFFDYESTWMNRRKADFKFAYRYLEDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRG9</accession>
    <name>A0ABR1WRG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multidrug resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006357</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669595.1">
        <property type="nucleotide sequence ID" value="XM_066810672.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043732"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Pleiotropic ABC efflux transporter N-terminal" evidence="4">
        <location>
            <begin position="83"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="188"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="30207" checksum="7DCA109E4EE5577E" modified="2025-10-08" version="1">MSLVGSSTAFANYDRTAKASGAPLTTTTSRDGMAGTNDPMEEAAASDTKTNATSVTDGDKKATDSGDSEEVELHRRESLVQGLARRFTSQSNVAGAHGGGNPFLAVDEDSPLNPASSNFKARTWAKAIVDMDKAGFRSAGVCFQNLNVHGFGAATDYQKDVANVWLEVVGMARKAAGLAKPRKIDILRNFDGVVRKGEMLVVLGPPGSGCSTFLKTIAGETDGIYVSEDAYFNYQGVPAKEMHTHHRGEAIYTAEVDVHFPMLTVGDTLTFAAQARAPRELPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRI0</accession>
    <name>A0ABR1WRI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669247.1">
        <property type="nucleotide sequence ID" value="XM_066810324.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043384"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="421" mass="46561" checksum="281FEEF123DD8278" modified="2025-10-08" version="1">MHDSVFSYNLTRPYPFKWFTPVTIVGGVIIAALVSFFNFASTGYELVPQPSSDPNETIHDPGQYGGIRWPSYFTANSRATCASTALPLRALIFTHNNAIPYTLTRVWRAKDDGSRLDLGSLVYHNNELQDCNVTRISIDVLGKYTMNQQVRAASPVGLSVNAFATCSVVIDTPEKVQRPTYFEMTGNYKLIGPDVTAFLSRNKTNATSLWWGESMLQMYWLVTARAYIDGAQDTDVGKDQTYNAAITLQRRESTDQGTAEETMSDDFFATGCFVEASYCGTNVTSELADPSKAKEDWHPYPKLWRRANLLGKAMYFTVLADLGRQDAPVPNMLTRPNLLANLTANLTSEVQWWKSASKKEGFAPHWQPDPGLSQDKFDPGQTPPPSLGAAPAFLSTNYICQVPRVKAGDPGDVDMGRLVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXB2</accession>
    <name>A0ABR1WXB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670695.1">
        <property type="nucleotide sequence ID" value="XM_066807077.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040137"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="26731" checksum="571664C20FE8FDCE" modified="2025-10-08" version="1">MAYMPSQSMNQQWNDSQWTQGDEQDCGGFLFDSFNGVEQLVLPLEQNMFSYGDFEEGMMSYDLQHYLHDFQDIGFISSISTETPSITGTLSSSEPIAWNTSRYATANRIPTSPVAGIDTLTVPVVSSLTVANPNGLQDQDSVDVAVSPSSDRRSSALSHTAPLACSVCGMQKNSMKDLRRHIVETHEKPFHGERKLVAFVRHRDGFGAPSCANAVKVNQIMIITWSISEDVELEGDLLDDQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYQ4</accession>
    <name>A0ABR1WYQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003256</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671189.1">
        <property type="nucleotide sequence ID" value="XM_066807571.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040631"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="18"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="246"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="33832" checksum="E7CA8C2963F20244" modified="2025-10-08" version="1">MVGLLAQVDLIFAILGAVWSKTSWAITLLRLSKGLLHNVILFIVISINILMGLSIVFNFIQCIPSRKLWEPYLEGACWPSQIVPIYSTVSGAYSGAMDITLALLPWFLIMKVNMRLAERIGVAVAMSCGVFAGATAFVKTAYVINLGSKDPIYDTAPLVVWSHAEIAVTIVAASIPVLRVLAKDVPLSAIWIDSSWLLLKNTFSSKGTTSTTLSSSMVTTTTTTCSANPADQRRNNAVEDDKGYDGTYASTFSETSPQRGRGMSRDGSSERELLPIGAGVGGKGHMVQEEASPQAFEFDHCRRALDFRFACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYU8</accession>
    <name>A0ABR1WYU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671235.1">
        <property type="nucleotide sequence ID" value="XM_066807617.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040677"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="171" mass="16606" checksum="9E959DAC6140391C" modified="2025-10-08" version="1">MANILQANANNGNANNNNGNANNNGNANANNGNAANGNANAGNNANAGNNNGNANAGNGNANAGGAAAGGAAAGAAADFGSCTPTMDFQLGRANRKATEGTFLPSDPAIAAKQSDALNPNIITNRICDELTNQCGANAAAKALCKQAQATVQGLGTKDASTADAFNQALGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ51</accession>
    <name>A0ABR1WZ51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldehyde dehydrogenase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003397</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671330.1">
        <property type="nucleotide sequence ID" value="XM_066807712.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040772"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720:SF2">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="503" mass="53769" checksum="46B9CA53EEA018ED" modified="2025-10-08" version="1">MEVEITAPNGHTWKQPIGLFINNEFVKPRDANTMAAVNPATEEVIADVYLAGEADLDNAVQAASDALASPDWKDLSGTDRGKLMSRLATLMEAHAETLAAIESINTGKAYRAALEGDVADAIDIVRYYAGYADKSFGQVVDVSGAAHHKLAYTVKEPVGVCGLIVPWNFPLNTAVTKLAPALCCGNAVVLKPSELTPLSVLYLASLAREAGFPPGVINVLNGLGPAVGAAMAAHARVAGLSFTGSTRVGQELLRLAGGSSRMKQVTLETGGKSPLVVFEDADLGLAAQWAHMGFTYNQGELCTATTRILVQDGVYDRFLEALVETTRRYPVGQPFDEETYLGPLVGKDHYDRVMGYIALGKEEGAREILGGGAKEGFAKGLFVEPTIFVDVEPSMRIYREEIFGPCAVVLRFRDEEEAVRLANDSIYGLGSALFTENVGKAHRVARRIEAGMVWVNSSQDSDFRVPFGGVKQSGVGRELGEAGLSAYYNIKAIHVNVGSVPPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZR5</accession>
    <name>A0ABR1WZR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipid transporter atnI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671488.1">
        <property type="nucleotide sequence ID" value="XM_066807870.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040930"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF154">
        <property type="entry name" value="PAP2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G09730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="176" mass="19514" checksum="A990B71A2472C3F1" modified="2025-10-08" version="1">MWLDPPPAQPISSHLVRVSYSRVDLGHRFPFTVKETVNSKLLLICNAVIPIAVILFVALVFVPGNTVPKGTPKSLIWKRKLWELHTGWLGLALSLTGAWFITSGMKNLFGKPRPDLLSRCQPDIANIQQYIVGGIANMSSNGQLVSANICKNPDTKLLEDGFRSYPRDTRARPPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X090</accession>
    <name>A0ABR1X090_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ADP-ribosylation factor GTPase-activating protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003804</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase-activating protein for the ADP ribosylation factor family.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671737.1">
        <property type="nucleotide sequence ID" value="XM_066808119.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041179"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07608">
        <property type="entry name" value="BAR_ArfGAP_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="316"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="8">
        <location>
            <begin position="502"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="216"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="462"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="678"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="739"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="252"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="462"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="678"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="744"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="762"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="788" mass="87833" checksum="F796AA0A8F4071C0" modified="2025-10-08" version="1">MKALEQKTGNMRAQMKKVLKKADHAYVAQLEANDAFMSFIDALREAASTNANAVQPALNHYFDHIAKEIASYERQNAINLQKIIVEPVSRLYTYDIKQAESKKRDFEEESKDYYSYVSRYLGQRQDSVKTKKLADSDTKYQTKRRNFELKRFDYSSFMQDLHGGRKEQEVLSHLTRYADAQARGFLNTAKKIDNLLPQLEALSTEVQEADKEFQYQRREREEKRRVLEKSNLQYNEPEGCQPRRGDLGRADSTGSQLRAVPTSNSGSATVGSEITRSPGSLHQTAGSPAQNAKFKGIRDLEERDLSMVAIAEKNSAQRKEGLLWALNRPGSHVDPRALTKQQGWHKFWVVLDQGKLSEYSNWKQKLDLHMDPIDLRMASVREARNAERRFCFEVITPQYKRVYQATSDEDMNSWIVAINNALQSAVEGHGLREKPSTASSASDTPSLKRDIGSILTGKSISLNHGHSQSVSGSAVPPRRTTVGARPGLSHRPSSSTYDESPDKLLQSLRDNDQGNCWCADCGSGSKVEWVSINLAIILCIECSGIHRSLGTHISKVRSLTLDITSFTPDIIELLMLVGNRVSNMVWESRLEPNVRPGPQATREQRLRFITAKYVDRAFVEPISATLSRYPSADETLLAAIKRSEIQQVIYALALKANPNVLDKSRGTHPVFLALAAADPASPSPTTTSAEGRSEPNIRTVPFPIAEMLVQNGAEIPSTMPAIPLSRSAQLYIEQKRGRAAAIEGTGPSTGASSLSPSPSERLPQRDKDRLQKRISAGGRLARSPIAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0E6</accession>
    <name>A0ABR1X0E6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">C2H2 zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003793</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671726.1">
        <property type="nucleotide sequence ID" value="XM_066808108.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041168"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF70">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="360"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="388"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="132"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="284"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="474"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="538"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="588"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="770" mass="82727" checksum="0E10376EED5BE0D7" modified="2025-10-08" version="1">MASEKGPVATEAPPLPASTISEPAIQHDPFSVESLQADATRATASLKRARETTPTSPSSVFTSHLGSDLSPSKAARLIGLTSRHSPAPLTGAAALEDEKRRREEEYRQQVSGASENPAYRVQSELMSASALAMSRPQDAPVTNDAHPDEQIIDHQGDDSIPPQTGGDMDQPEQAEQPDHVEQPVLPEHAEHNEHTELAEEHVGHTDHADHAGHAEHMEHPEHTEHPEHPEHMMHTEPTEHMGHAEHAEHPGHVEHVDHVEHMEHRSDVAAEQAANLAALSNNAAHVTASPGPMDIDGRGDRAGYAPQPQAQMEDKSNPTSLSYPGMVPPSAAMPAPPRTMSMPMTPNQPGGPKSPNSKKHKCPYCETEFTRHHNLKSHLLTHSQEKPFVCPTCQMRFRRLHDLKRHGKLHTGEKPHVCPKCDRKFARGDALARHSKGPGGCVSRRGSLGFETEDYSHLDVDDSTMTGVVYENPNEADMTEEERRRLSMSGMKAPHVQGNEAEPHESLHHLRTYSPPGTSTGRLYPPNVERGSNAPHAANASISSMPSSGPNSMYAQSGMTESPKPLSPGLQPHDGSVARQRSPSLTTQFQQQQFGRQQADRQTSSGSSSLPSYPEALVAQLVSVSGFPSSDGHYAAAGQAGAPGGISSAQAASAAVGQSNIGAASAGAQAVSSTAASQNGGSGDSTSNNIFATDQGIWAYIHSLEERLTETNTRVSILEQSEKNHKEDFGHLMDEVVSLRKQLEMKEEAPAPKLSSDRGASLIGSTAACF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0T7</accession>
    <name>A0ABR1X0T7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003991</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671924.1">
        <property type="nucleotide sequence ID" value="XM_066808306.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041366"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF1">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="9">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="185"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="247" mass="26726" checksum="63ACA39F00E615C3" modified="2025-10-08" version="1">MSIRQIHGILAAIAFVGLFPIGAILMRVVPGRFTWIIHGVFQILAYGLYVAAAALGIRLVRLVRIPPDGASMLSSARANVHPIIGLVVLGVLAFQPLLGWLHHIRLKRTGRRTAWSHLHLWLGRSAIILGIINGGFGLELANAPDSAVTAYSAVAAVVCLLWLLSALVFEYRRWRTPCKTAPGHAFPPPPDYDVPPPYNHATATQHASDRLGPDHRANDIEMGPVKQARRNSPASISSVSSGRVAHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0U8</accession>
    <name>A0ABR1X0U8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671942.1">
        <property type="nucleotide sequence ID" value="XM_066808324.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041384"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="66" mass="7394" checksum="E84726C562C0291A" modified="2025-10-08" version="1">MAPYKKKAMPARRFRAGSSPVLPKPAKYFSDNQELSLAQAPIPVFIYYYSSAAERLRRTQSIPSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1G3</accession>
    <name>A0ABR1X1G3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004219</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672152.1">
        <property type="nucleotide sequence ID" value="XM_066808534.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041594"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="24"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="93"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="315" mass="34226" checksum="D114E3EB1083EA7C" modified="2025-10-08" version="1">MAGEKRKRPYGVSCLACREKKVSCDGQRPRCGGCKDTHEECQVPAPARPLRRLQNSKTSTSSKKSSEPSVAELADRMVRMEERMRQMEERLDLAPGQGWSSLPGTPSAQGSPPATVASQTSAQVANSPAETDEGAKYRLTVDASGNVTYHGLTSWIRGPNVASEAPPQASSPIPPGMTDDPQYCRILQALAASKHISVAPKLGDALLDYYFCYSVFNIIDRSIFMRDMALGGPMFSEFLLMAMYTSATSKIDGLDHEERITQEALFSQLAKEYLAKEMEGPTKITTIQGLLLLSGRECAAGNVSQGWNHAGLTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1T8</accession>
    <name>A0ABR1X1T8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672206.1">
        <property type="nucleotide sequence ID" value="XM_066808588.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041648"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF97">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="2">
        <location>
            <begin position="250"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="539"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="636" mass="69868" checksum="DC16C96327D123ED" modified="2025-10-08" version="1">MSFSSIFMAPSTPAQSSEPRPGTLRSSRSFPRSAVQETTIDPLTRAQRASTFQNGTTTPEIKVIQTSPKKQGADPDSRDTFETAEAAESTEPPRASVDIEDIPIELISLTDNFIDGLSAKVNPVPPNVDNLSRRFQDFYATASHHIQTHIDSLASRQSRYEAPRPAVPSRASTASILRAKAASLTGKDKPKPASTTDGEQQMLTAEELANRKKARIALEQKKILLEEGVERRLCEGIYDRIYRHRSTHDAEADEKLRSKTAALSLVGIGLAELGLGIKADEHAEDGTDAAALEKQEEIRRYLEQARKNLITMHEKRYPLGKLNYLKAAQKSIVDTLSHFQLSSSADEIMPLLIYTLITMPPEQLDVTSDLKFIQRFRWEEKLDGESTYCLTNLEAAILFLDTVDLASLRADESVTGPAKLGSMSGSPRTETFPPAYTPGISEPTHSTPSLTTTEAQGLKAPPSPTTAKALAQRRRLSDLIQTPAQAIGNARDSFFDTADQSFKNISNSLGDSYNFFIGRLRDTTESGKELVVPRTLDDARKLIGTPPPEDIASLDGPVPAQGREEDSSPAANRDDRILHLVGGRKVPRDRDRSTDSTRSARSASSSKKSSLRLKKEKKPGPLDPRPQPPRLLTRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1V1</accession>
    <name>A0ABR1X1V1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">E3 SUMO-protein ligase pli1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_004346</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672279.1">
        <property type="nucleotide sequence ID" value="XM_066808661.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041721"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16792">
        <property type="entry name" value="SP-RING_Siz-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.780">
        <property type="entry name" value="PINIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023321">
        <property type="entry name" value="PINIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038654">
        <property type="entry name" value="PINIT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031141">
        <property type="entry name" value="SIZ1/2_SP-RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14324">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51466">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SAP" evidence="12">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="PINIT" evidence="14">
        <location>
            <begin position="133"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="SP-RING-type" evidence="13">
        <location>
            <begin position="347"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="429"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="479"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8089385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="60337" checksum="9B27E7880E385E67" modified="2025-10-08" version="1">MASSTSAREIQSLSAQLGHMLNKQLQSICQLNGLKTSGIKADLQKRIIEALQENLHADPALYAQLRSTIQSMSSGGRGAHQAHQNNGASATGSSRGSAYGTSPGIPSHVVPNYGNGYAQYGGYGQNRGFGGASAQGASKAMLQFKPSPFYTIQSQIGNIRTCDAMAQHRNSIHFALKTSEHPSLLQCAHDKTTRVMVFCAAEDQGIQEVAFPHQSELKVNGGEIKANLRGLKGKPGSTRPVDITSSLRLDKHSYVNNIEFTYALTQKVKTNPQTPVSHSNSHHPKGDEHVPCLAILCGKRRSLDFRMKFFLAVYLCRAVPVEELVTKIQGRRIHKDSVIQELTKAANDPDVVATSQVLSLKCPLSYTRLRAPCRSTSCNHVQCFDATSYLQLQEQGPQWICPICNKSATFENLAIDQYVKDILDHTSESTEQVTIEPDGQWRAQASSEPEPKRPRYSSGANASVIDDDDDDVVPLDSFSLPSARNTQTPNQSLFGTPGPAQGNGSVSSASRKRPAEVIDLTLSDDEDDEPVRAPKRQNAGQTPSLGPNIPKFPYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2X4</accession>
    <name>A0ABR1X2X4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004663</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672596.1">
        <property type="nucleotide sequence ID" value="XM_066808978.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042038"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056236">
        <property type="entry name" value="HMA_PCA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594:SF4">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24534">
        <property type="entry name" value="HMA_PCA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="724"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="764"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="9">
        <location>
            <begin position="110"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="PCA1 HMA heavy metal-associated" evidence="10">
        <location>
            <begin position="450"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="8">
        <location>
            <begin position="605"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1017"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1030"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1053" mass="114395" checksum="9FD3D58F3F20C8A0" modified="2025-10-08" version="1">MNVSFDQLSGGDRAQVAYSLPPISPLTGSPLGLVVVTSLLLTGVTLFVALRVLARIMTRGAEHQGGEYMGLRRHAGGVWFREQLGLLYTVMGHCDDPHGSDQGSRLVPQLWFIFAFSAGVFVWELADDIATCDPIAATWNPALGTCSIDAFLAGSSGMFVSSTISFALDISCVVIAWRLLQDFDFLKQARWALGVLFVFAIYASIAPLARFHSFDAYAGPHESLYKLDDIMIWSNTEAGVALIVISVPSLARISMGYFGERNGGLVRKHRRGAPVTNTGSPIQDTIEFYQSDRLFVGDAANAQIPLLRPTAARQRKQAVAMRQSRGRIKQEAIRWLLPKRSWELQSYHRLETTKKADCCKPGARANDCIDRIALRECEDIREYNKPLQQICGWMMRDETGPRLGILQGITNLKASLVMSRAEFDYDSRIISAAELTQQLERKTGFLCEEISTKGASLDVLPTGDVKAFTQQALPLGVTAMKVVDKDTVRINFDPKVVGARDLIERTFNTPLELAPIRRGSDPRRREQTRPARRLIEMDLLIVPQYQRSPISFRSFRSAIWLLEGRWPRASFFETSTLLVTLIMVGRFVSALARHEALKSISIRSLQETQATLVSIDGGVPEKDVDSRLLQYGDVFKLKPDSRAPTDGIVVSGSSEVDESMLTGESRPVEKHAGSLIAAGSMNSHGSLIVRLTRLPDENTISTIAGMVDDAKLTKPKLQSMANYVASRFVPVVVGLTVLVFAVWIGVGIREQNRTPAESAIRPLYAIAVLVVSCPCAIGLAVPMVIVIASGMAARRGIIFKSAAGIETVHKVTHIVFDKTGTLTEGVLSVAAEEYVRGGDHASTAAAILGLVGDIKHPVSVAMASHLRNRGIEPTVVCDVKSLTGRGWKDSWERNASKQAIPAGLASKQEDCVRETSARGLTTLCVTIDSRLVAVFGAIRLDPGDELQAVTAVAETIGIPPSMVKARCSPADKAKYIKDLISASSPVTHSGGNKAPTNNVIFVGDGTNDAPALAKATTGVHLPPSTSSAAARRRLVRGRRRAPPLLARGARRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X355</accession>
    <name>A0ABR1X355_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672742.1">
        <property type="nucleotide sequence ID" value="XM_066809124.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042184"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="445" mass="48972" checksum="8DD8D515EA2D6173" modified="2025-10-08" version="1">MAQPEDVEILVHINAPSRNSDDARYRALTSAYLAFQACPSSSAGELPESTDRRDSVARVQDGASIFQTSQAVSTQEFFPSLRSPQASFDSVIDNANSPNALLHVHRIGAQGGTPQTPDRSALSQLSWQTPPSVVQDSYPDVNATTLFNSPTRVLEYYLQQFPSASEASTPQLDSQGRDTHEYGVNPDITKSPSEPWLSVQHGGNRYVPTIPCTPGNGTALVLSSVDMDPDSVIPELDKTGAARADSEPPPSKRQRQRQTQTTDSPQGMLRTSSDIGQRIPHSSDQGRPITFTTQNGYTLDSLELYAPEPPTDNANLEPDDLITDGLGKLGAALQIPKRFRPERQSRDLRPFERGYWSLDCSDWTSELRSETWVFLANYVGGGVAGWGIWCRRDAGFNTLKVYCWGHVVAHIFLVLYLASRRKILYTGATWIDGDSKPVIVMGKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3G4</accession>
    <name>A0ABR1X3G4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672852.1">
        <property type="nucleotide sequence ID" value="XM_066809234.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042294"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="305" mass="33382" checksum="D4D9EFC63A9C26F4" modified="2025-10-08" version="1">MTGLRPARWPRFARAPRLDHVEASIRGTSSSRSSSCQKIATPTTFSRGLTSTRNFAEGDAANRRELPEPSLFGNSKRTKRFDSGHEIAAFYRAHKVKPAVHMKNIRVPQSKISGLAVQVSQSHCFDSNHMKYLDKAEHPLRKTIFDMYAGWADRPLWYSGAGFGAAPIVCSKAKRWIQRGLREALLERGYDRDGRVVQQKTPAAGRGAGNSGGRKAPPPALHGTLKVFSRIPKTICSHTFPEVLAAMRQALAAALPHLTTDGFARNPGPRGENYGNGNSFKSPRASQRPPIGKARPTGKARPPGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3L9</accession>
    <name>A0ABR1X3L9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH dehydrogenase (Ubiquinone) Fe-S protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672894.1">
        <property type="nucleotide sequence ID" value="XM_066809276.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042336"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger CHCC-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="179" mass="19756" checksum="F86C7B54D6CD3EE3" modified="2025-10-08" version="1">MLPRLAVRTALQLPQRAAVAQRAAAFSTSSRLLVNDAKAAILDNKAETTPEAKSEEDSTGLAENEARGLMQAPNRKEIWSRSQRPRAKAMTGPRFEQTDFDLQPQSKAAIELIHKQPVRWTHDRVVACDGGGGPMGHPRVFINVDKPEITPCGYCGLPFAHEHNRKHLESLPETSYPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3W1</accession>
    <name>A0ABR1X3W1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA mismatch repair proteins mutS family domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005049</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672982.1">
        <property type="nucleotide sequence ID" value="XM_066809364.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042424"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03281">
        <property type="entry name" value="ABC_MSH5_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="6">
        <location>
            <begin position="818"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="712"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="85"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="721"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8090088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1006" mass="110575" checksum="677E4FBE712A04A5" modified="2025-10-08" version="1">MQPRRATPYQGAPSQFPPGAIASTPPLPVLVRGSRSSSSTPQDGGRRYTSSSSLFIPGSRSRPSPAAVSRASAYSPQLPPHPGRPRLSLRPSSLRASSSSDRSLSSEGNNDGQDQGDDRFGVDDADALNEVILALDMKKNGNLGCAYYVASEETLFLMEDVSMAGLEIVETLLLHAKPTTIMVPPRISQEAHDKLQRGAHSEGGSIQDGVQGAYILRTLKSTDFHYDAGVDKLLGVQGQVAAFHDMHHGPMEDVRLDREILDHQYGHSQESRMRLGTIINIESRLAIGCAGAVLGDLHRRRTTQYLPNDPDALVAFSVRSVAMFTLFDSMFVNADTMISLQIIQPEYHPNGQMRGPDKSSSGAKENLSVYGLFHYLACTPQGRHRLRQAFMRPSIDIDLIRTRQRAIAFFLRPGNSETVMQLGKDLRKVKNMRATIAYLERGVDSPGRNVSVRNGVWASLQRFALYALRIRDALSQMMAAETIPVIMRILERVRPGPLVDVGEAISRTIDFEQSSERERTAVKRGVDANLDEMKRQYDGMEHLLTEVSEKMRGDIPEWAQHYVHNCVFLPQLGFLTVVSLNEQTGKPNYEGEGLNDAWEQMFVTDGEVYCKNRRMKEMDEHCGDTYCMIIDREIEILHELSVLVLSHQDAIRDASDVIGELDSLLAMAVGSGKYGWVAPRVVPENILRIEGGRHPLQELVVPSFISNDCGLAGGSGDEQDSNPSDETASASSSVDLPTTLILTGPNHSGKSIYLKQIALIVYLAHLGCFVPADRALVGITDRILTRIATRESVTRQESAFAIDLRQAAFAMNFATRRSLVLIDEFGKGTNSQDGAGLLTALLSHFTGLESERPKVLAATHFHEIFENAFLTESPELAFAHMDVRIDFDATAPEDQVTYLFKMIPGRSMSSFGTVCAAMNGIDETVVERAESIVLLLARNEDLEAACSKLSDAETSRLEKAEGVARAFLEQEIEAVRSGGRMQRTGGKYRAMLEQILGSGASSSTSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X457</accession>
    <name>A0ABR1X457_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone-lysine N-methyltransferase, H3 lysine-36 specific</fullName>
            <ecNumber evidence="4">2.1.1.359</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">SET domain-containing protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">PG997_005171</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60324"/>
            <dbReference type="Rhea" id="RHEA-COMP:9785"/>
            <dbReference type="Rhea" id="RHEA-COMP:15536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.359"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.359" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673104.1">
        <property type="nucleotide sequence ID" value="XM_066809486.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042546"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19172">
        <property type="entry name" value="SET_SETD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1740.100">
        <property type="entry name" value="Set2, Rpb1 interacting domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006560">
        <property type="entry name" value="AWS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025788">
        <property type="entry name" value="Set2_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050777">
        <property type="entry name" value="SET2_Histone-Lys_MeTrsfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044437">
        <property type="entry name" value="SETD2/Set2_SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013257">
        <property type="entry name" value="SRI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038190">
        <property type="entry name" value="SRI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22884">
        <property type="entry name" value="SET DOMAIN PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17907">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08236">
        <property type="entry name" value="SRI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00570">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51215">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51568">
        <property type="entry name" value="SAM_MT43_SET2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0678">Repressor</keyword>
    <keyword evidence="10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AWS" evidence="20">
        <location>
            <begin position="131"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="18">
        <location>
            <begin position="187"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="19">
        <location>
            <begin position="311"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="17">
        <location>
            <begin position="566"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="495"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="632"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="748"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="782"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="500"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="514"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="546"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="639"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="831"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="841"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="869"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="906"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="921"/>
            <end position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK8090210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="936" mass="105213" checksum="A6F88DAD600412E1" modified="2025-10-08" version="1">MMEDEERVKDGLENLKVETGEQGSGIDGDGLVKQEKGSALPSPDRSKGSRSRTRSRSPSMSPDEQKARSESASTPDGVAPPKLQRKASSKAVPRKAPLFTELPDMTEASKEHFQVIPDCLYGSKSLGSTEHDALDCDCDQEWRDGTNHACGEDSDCINRATKMECVDQECNCGESCQNQRFQRKQYADVSVIKTEKKGFGLRANRDLQANDFIFEYIGEVINEPTFRRRMVQYDKEGIKHFYFMSLSKHEFVDATKKGNLGRFCNHSCNPNCYVDKWVVGNKLRMGIFASCKVQAGEELVFNYNVDRYGADPQPCYCAEPNCIGFIGGKTQTERATKLSDATIEALGIDDGDSWETAVAVVKKPRKKRAGEDDEEGGVQKVMASLMQCKEKWIAVKLLERIQACEDRVLPYVQRMHGYEFLKTTLNTFRDDHNVVLQILDILDKFPRMTRNKIDASKIELAIQPLTDSEHEDVARESKKLLEDWSGLETGYRIPRKARNAQGTPNNTQTANSFGERRSARAEEPVSAKPAPVVPLPDNVPKGPRSTVPQRNTNFQTQRHRRPPDASTLPAGWFIATDKTNGSWYYYTKSGQTTWHKPTAPAPEIAAQQGSFKAIKEQKTLQDIIDSLTKPDSTAALRRSASQTPQHVTTPAQEPKKDKWRTLPIDKQMKIYENTLFPHVKYVMDKFRHKLPKDDLKKFAKEINKKLVTSDYKNKRVDDPTSISDKQEKKVKKYVKEFFDKAVQKYTAHEKKKADRTVQSGNAESMDLGSSFDASAQDAEVVLTDDEDAAPTPASSERKRKREEDDAGSATATPSEIPIIKRLKEDEGGLASPPPPPPPPPEGDEPMDVEVTEQDRIMQEQEDAQTSADFAERERLREQEAALERENELNMLDFEQEQQGKDGVHSSIGTADSNSNMQEGSDMERANEATKQEVMSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4J7</accession>
    <name>A0ABR1X4J7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673218.1">
        <property type="nucleotide sequence ID" value="XM_066809600.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042660"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="114" mass="13166" checksum="4F439FE0861EA997" modified="2025-10-08" version="1">MATKPDPAAEAKSVKQEGPANGEWSEEQLEEGLKQLKLLHIKCRELRTSLPRMLEPISTHNANTSRELTDFRKLYQSNESKEVLEHANKSRAADPKNIKPWRPKDHPDWLELEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X556</accession>
    <name>A0ABR1X556_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673376.1">
        <property type="nucleotide sequence ID" value="XM_066809758.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042818"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="35287" checksum="1C0B9D2BF8DB32BA" modified="2025-10-08" version="1">MTGARTTVVSLGAAAPAASASGTPGIVFGKNMTASVSLSFPLVSGSMSASAFSSSGKSASAPGSKSSSEYAPKETQSSSSSSGDVFASAQSSDGLKQTFGGIAFWIPAPSVPGIRGLTSEDDAPGYFEALRAPNLTGAYDFATPNISAPRAPGKVTEESNSALPGWSISIAVRAGVPFRQTEEHYTAGEVVLHAPESLLTNITDEGTGQKNVTVLDEWELCLIQWDLNSEPYPPALRGDDGTCSSILSPDCTRDLQAEARKQCSNLNITNIPACTNDDTRSFRTSSVAGTYPRERNPPVSTWRRGSCCPSPRSRPMEAPATCPLTTTLALSPGRCYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7U7</accession>
    <name>A0ABR1X7U7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673569.1">
        <property type="nucleotide sequence ID" value="XM_066806273.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039333"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364015" evidence="2">
        <location>
            <begin position="19"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="459" mass="50985" checksum="012D7FCCB097FA37" modified="2025-10-08" version="1">MAAGRFLAASLFFAVIFAASIPDTENGVNNHANDDNGEQQELSWQSAFWAVVAIALCAATEPSGSILGMPQEWGFALKCSPVMCLFNTLDALRCIRIERHGSRWRLMVRFTKYSGPAPNRRQRTTDANTVVRLVSFILGPLMQSIKLFACSGILYTKLLVACYLASFLCDELALNAVWLSTVERDNQHHAAPSSLVASVLYMLGQHPRRPQGEQVIAVTGRPPRTESPDLLPLPAQIAADLSITAISWFMCSLFFILLFAEPNLISWIRVICILFLAPVSAIIIAVKRLRRDGFTLRVAKDLALFWIFVTVWAIFGVDLEKGRQIVSMESTSRRLYAAGTPLLSWYAQSVGTGIIAVGIGMAGLRYVDAWAASNLSPPPPEMVSQRLLPTFLFAFPFDMVRWITGYKIWSPAGPEPSRVWGMLFPGLWCLLHFLTTLLLYYLIFDSSKTVKPGWTELLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7U9</accession>
    <name>A0ABR1X7U9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="6">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001875</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673486.1">
        <property type="nucleotide sequence ID" value="XM_066806190.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039250"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF103">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSIDASE MNL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="42"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="458"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="760"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="760"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="819"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="846"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1042" mass="116209" checksum="32194A1AEBED2C04" modified="2025-10-08" version="1">MLRIRRYRYFVAFAVVLVFILYRVSRTGDRWDDLSTPLPFKPLPKAPIQNPPAHDHDLPTKPQKVAQDEPSRQKPVKAAENEDVPVKIPTLESHDKAGKFDHPTTTTSLTRPKPTVDDSSDDVAHNKVQDHAPDTTKPPTIPAINIPDRKTPQEALQEQQKQAQAQVPLDNPQYVPTTTQVHWSKQPEHFPVAKESIIPLPTGKPKAIPRVQHVFGQESEEAKAKRLVRLGKVKAEMERAWGGYKKFAWMHDELSPISKAFRDPFCGWAATMVDALDTLWIMGMKEDFEEAVKAIGTIDFTFTDKRAEIPVFETTIRYLGGLLGAYDVSGGKKGGYTILLDKAVELAEILMGVFDTPNRMPVLYYNWKPAFASQPHRAANGASIAELGSLLMEFTRLAQITKENKYFDAVERITDALVDWQTRGTTVPGIFPERVDASGCNRTAAINAQIKLTQEEAARIKNTVTPPEDYTGREYDSTLKSDRQEKPDSLAGLPQGSKKTPPATKQSQPFGRRTLADDAEEIDDRPLTVKKGAAVPANKPKKPVISPPDLYQEMSMHGTTGEPYEDKYEKETCYPQGLTSGSSFQTYSMGGSQDSTYEYFPKTFLLLGGLEPKYKKLHMDTVDAVKKWLLYRPMVPNDRDILFSAKLSTTGNPEKDASIEFEATHLTCFLGGMFGLGGKIFEDEIDVAIGEKLADGCVWAYDSTASGIMPEGATVVPCRSADHCQWNETLWHEYLDPMFKSRDSEVADWEKRHAEIVKAKKDAAKRKAEITATSEKESIDADKDAKMAHPEQALGGAKSPAAAVENSAKTVGTANHDAPPADKQKEKEADWGTLRKRGLDTADALETSSNDNAPPSKTSKKMSLEESLDMNTAGGTGKVGMPLQVGAGQIPLAEVKELDETLAMPDPPRPFTHKEYVQYRLDHEIIPPGYVSINSRNYILRPEAIESVWYMYRITGDTKWQDKGWRMFEAIIKATQTESGHSAIRDVLVPVSDRTNEMESFWPAETLKYFYLLYSKPDVVSLDDYVLNTEAHPFLRPDASVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9B7</accession>
    <name>A0ABR1X9B7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Uricase</fullName>
            <ecNumber evidence="5 6">1.7.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Urate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002437</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>urate + O2 + H2O = 5-hydroxyisourate + H2O2</text>
            <dbReference type="Rhea" id="RHEA:21368"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="EC" id="1.7.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Purine metabolism; urate degradation; (S)-allantoin from urate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the uricase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.3.3" evidence="5 6"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674048.1">
        <property type="nucleotide sequence ID" value="XM_066806752.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039812"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.270.10">
        <property type="entry name" value="Urate Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002042">
        <property type="entry name" value="Uricase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019842">
        <property type="entry name" value="Uricase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03383">
        <property type="entry name" value="urate_oxi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874:SF1">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01014">
        <property type="entry name" value="Uricase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000241">
        <property type="entry name" value="Urate_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00093">
        <property type="entry name" value="URICASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00366">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3 5 6" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8092076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="296" mass="33430" checksum="C7DA90F58ECE776F" modified="2025-10-08" version="1">MARLDSASYGKDNVRVFKRERDPATGVETPSELLVCCLLEGDIDVSYTRADNGPVVATDSMKNTIYIKAKEFPVNPPELFAAKLGQHFLDTYPHMTAANIDIVKYRWTRMQVDGKPHPHSFYRDGNDTRNVHARVSRADGVEIRSSIAGLLVLKSTGSMFHSFVRDEFTTLPETWDRILSTEVDAAWKWKKFASVKDVEDKLAVFDKAYDDARNITFKTFAEENSPSVQNTMYVMCEKILEVAPETESASYSLPNKHYFEIDLSWHKGVKNTGKDAEVYAPQSGPNGLIKCEVTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA16</accession>
    <name>A0ABR1XA16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD dependent oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674221.1">
        <property type="nucleotide sequence ID" value="XM_066804448.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037508"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF26">
        <property type="entry name" value="FMN REDUCTASE LOT6, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045758164" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="50641" checksum="9AA305D33B3A837E" modified="2025-10-08" version="1">MRSLTTLVLSTSLAYAYPSVPGCWSKHKFAESDILQRDVLVVGGGATGTFAAVKLKDAGQTVAVVERDAQLGGHVDTYYDPASGYPVDYGVQGYFANQQTRDFFAKFNRGLLALPQKLADFSSGYIVPNAAAPDLATMQPLLTKYAGVLAQNFPYLAQGTYDLPDPVPEDLLLPFAAFAAKYDLLDTIPVVWTFAQGVGNLLEATTLYVLQNFGLAHVQGLQAGFVVAQQGNQVVYDKAGAFLGADAVLYNSKVIQLARGDDGVTAVVKTASGTKLVQAKKLLVTVPPTLGNLAKFDLDTTEKSLFGQWANVPYFIGVLAKSGLTDQISFINVNLTSPDTLPRTPLVWRIETVGVPGYQTVKVIGESSSKAAQRLVTDALTRLDRSLQTDASATEFVRWEEHDNLQLHVSAAELAQGFYKRLYSCQGKRSTWYTGNAWATDYSSLLWAFTEERILPSLLGSSGSQAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAB0</accession>
    <name>A0ABR1XAB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000271</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFP11/STIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674359.1">
        <property type="nucleotide sequence ID" value="XM_066804586.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037646"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022783">
        <property type="entry name" value="GCFC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022159">
        <property type="entry name" value="STIP/TFIP11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045211">
        <property type="entry name" value="TFP11/STIP/Ntr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329:SF1">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07842">
        <property type="entry name" value="GCFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12457">
        <property type="entry name" value="TIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="G-patch" evidence="8">
        <location>
            <begin position="208"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="240"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="793"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="803"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="819"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8093586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="921" mass="102741" checksum="5AC97A7E138B2A2C" modified="2025-10-08" version="1">MSHDPGNTSKADAAAYSSSDSDDSAVDEFTDFNPRKRRRTGRNAKDDAALGIFGSDSEDDGPGRRWKGKKDLRHKGMSFVSGGKEKLDEEDEDEDDEYAEPGQFGVGSKGTVPDDDEEDEEDEDVAMGGVGLGFRPSAPTETAAAPTSTSRPSFVKPKYDGSTPLGRGFVPSSATEPVLKQGLKDEPAMASNAPKPSAFTKSGGGGKAMSFAARMMAKMGYVEGKGLGADGQGRNVIIEPTLRPQGAGLGAVKEKSKQEKEEEKRQKRMRGEEVVDSEEEENKRKLERGKKKRAQGLDSGTASGASTPRRPKTKYVTVNDMKKAAPGLHIPDAFAPILDMTGPGQKMLTSGSGLLTPTAGTETVEQTEARKLAGRAQRDLTAFVEEWKTLEERKAWLDMETHQRQQELDETQAHFGKLQIFASVLDEITQAAADKEWDPVINGLRKAEAEGSANNEDLAGIAVATIHPFMREAVQGWQPLEDPKLGNFATDLMDIRGVLGLKNQATNGKAVAKWEQQEVDGTYRHHQKSTTPYESMIYKLLFPKLVTAISQQWDVYDPASLLAIFEKWGELFPGFVRSQLLEQVVRRLDEAVSAWKPRKKQHNLPHLWIFPWLQHLPVHHLEPKGTGLVADIRRKFRQLIDVWEFDRGVVPGLKHWKDVFRPSKSQDQWKPLVMHHIIPSMVKYLRTSFRVDPSDQNPYIPMLEGIMKWTEIIAPSMVAEVIVAEVFPMWHDVLYQWLTSDEADYDEIATWYQSWQDDILPDMAAQESIKAEFDKGAAMLEKAVELGADVQAKLPRPDGKPAHQPKSRSQHKPHADTSEAAVPEATAAAAEPAEKTFRREIEDWCNENDLRFIPMSKSTDRGEKYMRITARMDGKGGFLAYFQKGADLLVVERRKKDDIVMRRDQPEQWEHVSGDLLAEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAF3</accession>
    <name>A0ABR1XAF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000259</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674347.1">
        <property type="nucleotide sequence ID" value="XM_066804574.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037634"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF1">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="120" mass="13570" checksum="E2E89027EEE26C37" modified="2025-10-08" version="1">MNDCSILARCSLPVRIYRPSQPARTTVETYLVFLVILKNLLPGKSIPIAAPSSYWYLKQYPIKGIAKVVDYIRPDPFVYLKRTLDTLHQAQKGRQDENQDGHPEGVPLEARGLRYGDPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBZ9</accession>
    <name>A0ABR1XBZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ima1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000855</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674943.1">
        <property type="nucleotide sequence ID" value="XM_066805170.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038230"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042321">
        <property type="entry name" value="Ima1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018617">
        <property type="entry name" value="Ima1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538:SF1">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09779">
        <property type="entry name" value="Ima1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="616"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="639"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="680"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="705"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Ima1 N-terminal" evidence="8">
        <location>
            <begin position="10"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="350"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="499"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="357"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="458"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="729" mass="81872" checksum="756BFEE64166AE8C" modified="2025-10-08" version="1">MPTLRSRKFLSCFYCGKRTNLRFDGRQSFLCSHCEATNWLDEHGDITDPPTSTPLDAAPAVAPQYARSFNSRMPSEQPASSPDGSAMDSIFCASCLKNQHIYTEALRQFEIPDDQSDPEYNDRIRAFRKWRADLEQRYPQVCATCEPKVQRQLNKASYTAKTDHLRRVMDRTRERRREVKKRGALDVVDSAGKLAWNIAFALEFCWHASVLCALFVEDDEIAATTHWLIAPLRNTCYYALMFSPDADRFIKWSISLGLASFAWNPRFKQTIRGFTSHIFGVGQWYTYQLVILFIRLTCLFVSQYNDSKGIPAASQLGAHLVIALLMFYVYTISGRVVRLDTTPLFGANKPVSLVPADEPKPPPQGKRDDLGSILDEILETPPRPNKTRQENPSLSSPLRHSMSATRPQQPPQAPFELHPRRVQPMSGFGSLRLSDESSQTQPGPPAAQYGDEMDWAPSGSQHRAFSTHNPFKVKNPNPRFSDAPIEDKPGPFWYKIPPAPTTPAQRVRNPPMKPIIRDSPKDIPENFFSTTRRGPVDIGSPARNLEQNSMAFKESRFHAPQARDEATEGLSRLMGSFSLSPEPESRRFGAPRNKTNVFGAPNHVSHAPVNNSRVRMAELIILFGALWAWITALQSTEQYAPTLALGAIIINLAMSVRLAVDLGESQIQQGKTQALLRFSCVNLAALQILAAIVLLWRLWMDSNTTVAHGAYGSTLIGLTIIHHVWHVFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC13</accession>
    <name>A0ABR1XC13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675024.1">
        <property type="nucleotide sequence ID" value="XM_066805251.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038311"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="147" mass="17087" checksum="86CB0CAA376FFF11" modified="2025-10-08" version="1">MTSDECAAAKRRGRRRRPRPDGAAADEYERREIMTRMRDVTARRALLAARSDHCIDRLVISEHADHSASYVCNSSSSWGPDFVSMEERLYCDMCEHQLWKLCAGPEDSDCFDLDVHRLRLGSSLGRRTEDNEHVVLKEYISVKRWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC15</accession>
    <name>A0ABR1XC15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein SDA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_000808</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for 60S pre-ribosomal subunits export to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SDA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674896.1">
        <property type="nucleotide sequence ID" value="XM_066805123.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038183"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027312">
        <property type="entry name" value="Sda1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048292">
        <property type="entry name" value="SDA1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007949">
        <property type="entry name" value="SDA1_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012977">
        <property type="entry name" value="SDA1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730">
        <property type="entry name" value="HSDA/SDA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730:SF0">
        <property type="entry name" value="PROTEIN SDA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21638">
        <property type="entry name" value="SDA1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05285">
        <property type="entry name" value="SDA1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08158">
        <property type="entry name" value="SDA1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SDA1 N-terminal" evidence="9">
        <location>
            <begin position="98"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 middle" evidence="8">
        <location>
            <begin position="543"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 C-terminal" evidence="10">
        <location>
            <begin position="703"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="483"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="527"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="632"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="541"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="663"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="741"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8094123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="757" mass="85301" checksum="BA568894910C4401" modified="2025-10-08" version="1">MGRTALEKTEADLVTLQYKIRRDPQAYEKEFLELWNQYESTRDQFLAAPVTSESNVLISYRELVDLIAHCADRKLDSQPSVALHCIAAATLLLTRALLVYPEHTVGFADGLKETLTKHHAVLESDLREKIVTSLVLLRRKDVVDSGYLLTTLLPILVSTPSKSLRHLLFTKILSDLRNSNTKSINHKLNRTVQNALFTLVTSDRTSSKGLWAVKLTREMWRRQLWTDAKPVAIMKEACLSDNEKVMVGGVRFFLGSDQEREELQDESSDEETPDIKQVKHQIGINKKSKKKKKALDKAVDKVKRAQKKKNAPSPLNFSALHLLHDPQGFSEALFAKHLHGKSRLALESKLQVLQLITRLVGLHQLTLLSLYSWFTKHLTPRQQSVTTFLACLAQATHELVPPDVLEVLIQKIANEFVSEAAAAEVASAGLNAIREICARQPLAMTDTLLQDLVQYIKSKDKGVQMAARGLRSLYREQAAEMLQRKDRGKQATMNLKSGEQRQKKFGEQEVGGIEGLELLAKWKEDERKRKRAEKGLPEGGDANDEEEEEEEEDDGWEVASNESSDSGEWIRVSDSEDEDEPAPKKQKRDSEEPEDEGDAAKELEELSKLATTSILTPADLAKLRELRMEASIDKAMGNKKRKGDQQSRHFDEGLTAEQIEAPARLRKDTKEERIAKAKEGKGERSEHKSTQAIRKSKKDAEGKSTTNQEKARKKNFLMTLGKAKSKQKRSLVDTRNALKNHISRSKAGGRRRNGVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCE9</accession>
    <name>A0ABR1XCE9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000964</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675052.1">
        <property type="nucleotide sequence ID" value="XM_066805279.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038339"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="212" mass="23209" checksum="82625A6EB4CB6B6B" modified="2025-10-08" version="1">MPSENEYDAIIMASHKLRIATLWAGRNAKASGSATDDIGVRSNFQVQQVNRRGLHLDFLVVSNKSWRNPAGDPNEARGRSAFASFFYVVVLIRAGHQWISWILLVGAHGNASRCQAMAVLHHESAGWQAHMHECCPARREELRVDYIGMACRTDRLPSAKVRSSGLPMVDGHGRALDADHMRQSETTSGLPINGATPSVTHRVAADQFGSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCJ2</accession>
    <name>A0ABR1XCJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675107.1">
        <property type="nucleotide sequence ID" value="XM_066805334.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038394"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="721" mass="80206" checksum="6FEC899189523D82" modified="2025-10-08" version="1">MAAGDDETMPDAPAAKPRRRFAPQLVEESVKSSSSPTQDSFPANDKAQDHSSSQAPQAEKEAPRTTKDASVQVDDIPMADAPPAQSRRRFAPVPIETTFDSYRVNKNPHGPTAELTPDPSPTSSYAPHVEFVETIEPQEKKPKRRFTPQLIETSRRERRAGQQGPATKHTDKTDITPGTNHIYAPKPQKNRPPPANARNEDSTTLTEDEEEGEAHRYLTPRRQGSMKPHPNTRRSTPKTSFHLELDTIASSESDNSSEGSNDDTRDVDDLTLGAPVHEVKVDQWEQRDTNEKNRRESLDEDVSGYLLAVAASEAHRQRELESALSAFPNGVPALGVEHFYVRDNSEEFHYSDSEEEPLRHGTSKLIRRKSTDLPWAVKEMRQYAEKHPHFRFGSDMSVDTLSDDMDLPPEDPLWTTGGPTPESLDQHPPDSDSPATSHVVGKPLPPTAGPSAQPEVPGFRKGPFGNPFAAFGNDDNEKDDSHFREMRNAAAPPMLGSHLKFRMCPSPKATRLEPDHPWPMQGDSRPEEKIRDTSGRPPATLHDPFAAAFTESLSLGGSNAPASPTKRSSKHGGLHMEMARKEREDRIAAEFDDAFVTQVYNYLSLGYPAAARAYDEELGKITGLEISELRRDDGKKIEKGFMLEMQLNVKSGFGSQSSADTSGDDEMVSPEEDERRCADMPPRWTALRLYIREWARQHPDLENNGGTLAWGMRARRGSWAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD65</accession>
    <name>A0ABR1XD65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipopolysaccharide-modifying protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675349.1">
        <property type="nucleotide sequence ID" value="XM_066805576.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038636"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF22">
        <property type="entry name" value="CAPSULE ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="1">
        <location>
            <begin position="331"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="559" mass="64304" checksum="4F62D5B54DD53E71" modified="2025-10-08" version="1">MDLIKEGHEKFARLQAARSNTIEEAAGRYRERRGRHPPPGFDDWFKAAQKRDAVIVEDFFDRIYHDINPFWALDQPELRRRAHSQPEVIRIRNGKVTLVSEDPERGNQWMQIWAKLVKEIGHLPDLDMAINVMDETRVLVPWEKIDEYVKKERRTRDIFPASEAVSTYTGYADVDTQTEPYDPHWIGGEAHKYWDHVRATCPPDSDSRNIPSLPSFSGPVKDIYPTGPVDAYTYKGFVRNFTASQDACLQPHLRGLHGTFVESVSMSTTRELLPIFGGSKLPQNNEILIPGAVYLADDKRYSGGKGIGGSWEGKMEGFMWRGVASGGRNKVDNWWHFQRHRWAQMMNGTTLQKVIVADEAAAPTFTLLPPSVYNISARRNGFMGSWLAMHADVGVIDLMCCPGEVDSRKKRVHTCSYSSPFLDVVKEKPMREQYAYKYLPDIDGNSFSGRWRGFLRSTSCPLKATVYTEWHDDRLVPWVHFVPFDNTFMEIYAIMEFFLEGHDAQGRRIAEEGSRWASQALRKDDMLLYVWRLLLEYARVVDPQRNRLAFVGDLVQEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDB7</accession>
    <name>A0ABR1XDB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001247</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675335.1">
        <property type="nucleotide sequence ID" value="XM_066805562.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038622"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="402" mass="45112" checksum="05E2138A2E11A97E" modified="2025-10-08" version="1">MAEPLDFDEFVLSAPPDGLSLSVSSHIFLADQFDPQLDLTGLYDNMGIRVDGAVLVASDASDGFLEFLIESICQSPLWPSLGLSVVCTEITYETNDGDEPNICLEVDHPDKAASLISPPEAVTTSIEGLFCRFDYRTIVRGRRHHQPHIQSQQSPERVGENRAVGLPQSMSDQSNDSDDDRMQTDDMLDTRDEIDETCCRRRTCTAQLTVAALYRMIGIKPRFSGIQGITPIPPTLLDIAPAMWNAHYMELTRHHARQLPLIANIIENAGTWRRTLQDKISNLLNEHDGEPPIADYEQDPNRQHNPLHQHLWTLLRSNLMNKINIQSAAKKAHGILGATSDDAETRHFSSDAFPMSPGDEGGELFGYEYDDWEQDESQLPAYCAMQHEDDMSDYEITDQKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDC7</accession>
    <name>A0ABR1XDC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-mRNA-splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675473.1">
        <property type="nucleotide sequence ID" value="XM_066805700.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038760"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007180">
        <property type="entry name" value="DUF382"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006568">
        <property type="entry name" value="PSP_pro-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052584">
        <property type="entry name" value="U2_snRNP_Complex_Component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785">
        <property type="entry name" value="SPLICING FACTOR 3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785:SF6">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04037">
        <property type="entry name" value="DUF382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04046">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00581">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP proline-rich" evidence="2">
        <location>
            <begin position="295"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="581" mass="65334" checksum="5371A363E7217116" modified="2025-10-08" version="1">MAPQMTKNQKRRAKKKAEKASKPEETAQVEDSPEVQQDGAAPESEKPAENGETTNGTSELEVKKDDATAAKSQQTDGPVVEEFDFDNEDPAFAMYKHVFTKFGVSEDNDIAKEANAGNTGEVFFDDDDDIPDEEEEGANANKMSKKKRKMLNKLSIAELKALVKKPEVVEWHDTSSTDPRLLVQIKAQRNVVPVPPHWSLKREYLSSKRGIEKAAFKLPKFIADTGITEMRDAVLEKQAEQTLKQKQRERVQPKMGKLDIDYQKLYDAFFRFQEKPNLTRFGEVYYEGKEYETKGSHARPGELTDTLKEALSIPPGAPPPWLINQQRFGPPPSYPSLRIPGLNAPIPAGAQWGFQPGCYGKPPVDDSPSGEPVERTLWGELQPPEEESEEEEDEDEEDEDEDEDDGGAGLQTPSGIETSAGLASSVPTEYGTQTESVAGEMDLRKNRRGYETEESTHPRSAYTVIPERQARAEGFFGSDRAYDLSKSNAYGDMRVLGQDDDRGHKRKKPGDIDVALDPEALAEGGLGKDELKRRYEEGRRDEGPGAQWRREEGLDEMIANESRKRLKRDEEKRDERKKYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDF6</accession>
    <name>A0ABR1XDF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675439.1">
        <property type="nucleotide sequence ID" value="XM_066805666.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038726"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="57"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="31673" checksum="1A64199E7D4E552F" modified="2025-10-08" version="1">MEFHQESQSSWEANAAYWDTTIGQEGNKYWKVLQRPTLERLIPCGERPDGSGSSKALELATGNGLGARWLASAEGGGFGSVLATDGSAEMLKHAQRRQSDEAASAKTRYRQVDVTDAAAFDELLAGEPDGVGFDAVLLNMAIMDIADLKPLAKALPKLLKPDGAFVATMLHPVFFTSGFTRSIELKDGTGLDKPEITRAKVIREYLDVPPIHGVAEWGQPTLQGSTGAQIIFHRPIHEIFTTFFREGLVMDAIEEPAFTEADGVKERVEAHSNFTQLPALLAFRLRRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDT6</accession>
    <name>A0ABR1XDT6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675624.1">
        <property type="nucleotide sequence ID" value="XM_066805851.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038911"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="402" mass="46342" checksum="D66CE30EFBC2CFC5" modified="2025-10-08" version="1">MPNTGYIITRPPKPPKPLSKSAQLRGKVTEASTEVLKKAYNSIRDSAEKPDVKGAFKRTRKENAEEELLAPIHPNPQLGCILFKFPQEIRDQIYAEVFAATRVWFEYIYRDIFGKAPVKKKRKHHALALLSCCSRIRNEIGHSWLNHILLCCQSPQIMLEKLLNVPAPLSCVGYVRVHGLMGMMLAVRSTRSPSADAMVHEFLRSLPGLALEELEVVADGSGSGTWEYQAVELLLDRSFGWKKLTVYFPGSGLLGRAPSWSGREDEHFEYRHGLQGHVRRPLPWAFREVLLERDGADSGSTVDIFQGPQHDEEVTKLDILRRRILGLQHQDKEEAQFPELYYWKRDKNFDPRYQLWVVAQRGRGVNCTVPPLRMFAKHHWPYWRTREYLARRVHEANRDPDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE72</accession>
    <name>A0ABR1XE72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675732.1">
        <property type="nucleotide sequence ID" value="XM_066805959.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039019"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="463" mass="52355" checksum="64B0607162AC26A7" modified="2025-10-08" version="1">MGTIEQLRDQWINPSDVSTILMAIGGDVVQNAFAQGTGQPYTPVCFSFGCVAYAFTTLVNIIGDGRLLPSPDYPVKVFNLESGYARENKNWVVGRLLRDIESQVSRMRPLNDNTGIRISVFEAIENENNPTQFSWSFMHIIGAIMTLLQLGVATIPIALDRQWGVMFITIIGTLLIQIAGLLPQWRAEKLPNGQKSKDCYALTSGNGSTDIVVVLGRGLCLNLEEMSASQSPRINRPWEKFQRLSQPLDLEKMADSNRLGTRGRKAKTFHGFPLGFRLTQITCWVLSVLWLLLLVNVAASTDYTWCLLGIGAIGMFQNAWLAAVELPSAERNLPLYHCDTIMTHKVMDGIMDFDITYGRGVPLMEEFFPGRLHDEETEWWRGNKDPYDDIREKHSALRDVPRSRKRAIPTSTLDPSLEEKRKSWFDVDQPKSLSRINYEPSTRWDDLRTRDRPKGSTASPRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEK9</accession>
    <name>A0ABR1XEK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001729</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675817.1">
        <property type="nucleotide sequence ID" value="XM_066806044.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039104"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="397"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="338"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8095044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="494" mass="56049" checksum="2BB94F06E9686C65" modified="2025-10-08" version="1">MAPSAEQWQAPLARDVAAYNDAELDAFLEESKRRHGAYVVDVADPENIPDEFITRLRDRANAPARSQAIDLDQVTTRLLAASAETDTAQRDRSPTAPLSPTGSSERRHYEALVRAGGRPCYPIEELDDVMNDPHAYRDVLRPWVYHEDMNPSEWEVFQRQLSNWEGFRDWQKAIRDESWESSLRAVRVALSDFNRRRKPGFSSYVVAAQKLMETTTPFIPFELRPNTEEQDQLSTWTEYLVYARSLYTHCATTSQNLQIKLDAAWHSFESSVKLKPFETRDYVSSRDAKLRQTAAVRDAAAAFEAAKMDLSKLVPSDFDPSDLEASRLRAPPPKRRLLAAAVKRVKEAQAALVQAKERDGHYAKFYQATRDYESTRDDVGRLRRQLDWAEKQYALVKAEQDQSRPAHHDSVVERSRKRRRSIHDRGEDGTAAQRRAPGAKKQRLQTPNPAARSETQHSDAQSKGRRIPASGIWAPNNHGAAVRAPASVGGFETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQK0</accession>
    <name>A0ABR1UQK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660621.1">
        <property type="nucleotide sequence ID" value="XM_066819736.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052796"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="187"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8061201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="58289" checksum="A341697CAE8B54C7" modified="2025-10-08" version="1">MSSQSEQPRIPTNELGYEAFPQNSRFLSRSRLKDNTGRSRLGLEIGYHVPKTAQSHLIAELGRNADIMLPDDDALSSIHAVFEFSHTPCRILLRDRSGQASSVKCEPVSTQEMPAEEEGHIKFIWYITNGTQAMGKAIDGYEGSLRKARLRSSLNHPTDQIEPEKGWRYPPRVKTQSSLDSDVTAITEELKLLGRDRPGQIRLVKILNPKGGETCAVIKGFASAVGPVGSRALIKNEAKMMRYLNHKHIIEIEILVCQDGNEVIQIKMPQRHSLTTLTKLWFESGWIESRDWNAICCKVAEHLLSALAYLSGKSIIHLDVNPDNILYYLEAEGRSNDPGGSHRGGFQFQLANFAALEGMQTFCSLEGTPNHQDILLLIQKKITSQPLLQDTGKINPDERLSAADLLEKYFNNSRSIEPTAEAKRKEELAVARTCEIDMQDTEAPPPSGPPSQEIPSMQCIIYSPTRMRHPAERSAASRMPPPAKLTLESGVRKSGRATPNRTSRRTSRCPTPRIPRDFDLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTC1</accession>
    <name>A0ABR1UTC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator family: Fungal Specific TF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014286</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660788.1">
        <property type="nucleotide sequence ID" value="XM_066818600.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051660"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF50">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="113"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="189"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="772"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="800"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="884" mass="97950" checksum="A1C5145FED6F0B7E" modified="2025-10-08" version="1">MPPADLSAAGSEKGARIEPHSAPKPRSCVVCRSRKVRCDKLSPCSNCRRANIPCVLPSADRPPRWARRLDRANLAASSSNAQQRTTHDGGAAVLVAERLQKLESLVKDLTSQLEQAQASVPTNNSGSPANSTGSSTRREADNRADTPSRNLSRSATRQSGKLVIQDADRSRYVSSDFWSKINDELSALRMDNTHRPDEDSESSEDDGMTPESQPTDELHRTPLERNAFMFGHNLSSSPYSSSDLHPLPSQVSYLLDVFSDNVNFMAQAVHMPSVSKLARDMRTKGTTSLTPSNEALLFAIYYAAITSMEEDDVQSNFGASKSDLNHRFRVGFESAVARADFLNAPNITLVQAFIAFLCLARRHDSPRYVWMMVGIVIRMAQSIGLHRDGSHFPNLSPFEVEVRRRAWWALYMLDLRSSEDQGTDFTIAHDSFDTKIPLNINDTDIEPGMKEAPKARVGVTDTTYTYVSIEYTSTTRKLLSLELKNGIPDLDHLSRLLDEMYEKLDRECFQHVSKIGEIRRELGITVTRLVMAKLKLLIFVPLLLSSPTDYFSVDIRTVLFVSAIEVAEYNHSMNENAALTPYVWIFQTYTHWQSIVYLLIEISRCAWSPLVERAWVALHSKWLIPVNAFKMDKNKEISMPLRKLLAKARRHRIAELERLRRDSSAVRVLEEEDKKSSHVPASSGSCPLGVDAVEAFRSRWRQTLAAIPDTASQQKPGSSTTFPTQEDVHASDLAVLAGHMAFPSALPGMGYGDTGFPNPNNTGGTMTQGYLAPPNPRGATAAGHQTTRPEPDRSAAPSFMTASPSISTGGQVPSTGFAMNPVPGYDPQAFSPSWLWADMDPYADVFGGLEGSPGDKGMELDHDMNWSDWVQSARHMERNVGPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVP4</accession>
    <name>A0ABR1UVP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">50S ribosomal protein L36</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661608.1">
        <property type="nucleotide sequence ID" value="XM_066819420.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052480"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034600">
        <property type="entry name" value="Ribosomal_bL31m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048874">
        <property type="entry name" value="Ribosomal_bL31m_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28174">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28174:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL31M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21492">
        <property type="entry name" value="bL31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein bL31m N-terminal" evidence="2">
        <location>
            <begin position="50"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8063009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="21250" checksum="2D62CECD569AC816" modified="2025-10-08" version="1">MASRLPTALPRRPTTSTLSTFNTLAPQTTSSSIIPTLQQTQTRNATLIKRPKRPYAFTQVIQLSDGSTFTMRTCSPHSLYKSTKDTRNHVMWNPSEKSLKNIEVDEAGKLAAFRERYGRGWDAQAPEVQDGGEEAQAAAAGGAAGKKDGKKDDKAAANASFENKFDSSYDPLGDLISQYAVGVPEDKGAKVAKPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWD4</accession>
    <name>A0ABR1UWD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_014473</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660975.1">
        <property type="nucleotide sequence ID" value="XM_066818787.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051847"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001524">
        <property type="entry name" value="Glyco_hydro_6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF4">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001100">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00655">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044989189" description="Glucanase" evidence="9">
        <location>
            <begin position="18"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="11">
        <location>
            <begin position="29"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="72"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="72"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8062376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="484" mass="51211" checksum="E365646020691345" modified="2025-10-08" version="1">MAAKTFVLAALSSLALAAPLEGKIEERQNCGAAWSQCGGQGWSGSTCCVSGYTCVKSNDYYFQCIPGQATTTAAPAPTSTTTKASSTTKASTTKASTTSKAPSPPTTTTGSGTTTAPPAPGGSGTATWSGNPYSGVQMWANPYYASEVSAYAVPTLGAVANQVGKVPSYMWLDTRSKVPLMAEYLAQIRKENQAGASPPKAGLFVVYDLPDRDCAAAASNGEFAIADGGVAKYKEYIDAIAELVEEYSDVRMPLVIEPDSLANMVTNLNVAKCSGAQAAYHECTLYAISKLNKPNVAMYLDAGHAGWLGWPANLTPAAQMYAQLYKDAGSPKALRGLATNIANYNGWNLTSAPSYTQGNANYDEKHYVEAFQPLLKAQGWDAHFITDTGRSGKQPTGQTEWGHWCNALGTGFGIRPSANTGSDILDAFVWVKPGGECDGTSDTSAARYDFHCGLEDAMKPAPEAGTWFEAYFEQLFKNANPPFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UX38</accession>
    <name>A0ABR1UX38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661200.1">
        <property type="nucleotide sequence ID" value="XM_066819012.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052072"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="123" mass="12351" checksum="9C69461B80B5A0EB" modified="2025-10-08" version="1">MVVEGGSLSNLAWIVLRKNPTASASSSGNSTTQSPSLGMDSAKPPNSIFFQTGEDLAKVREQTLNVTATAWSCFSSPFAGSLAPSAPGASCISSITSGSSTASSPHVFSADSTSVASSKVSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXF5</accession>
    <name>A0ABR1UXF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014606</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661108.1">
        <property type="nucleotide sequence ID" value="XM_066818920.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051980"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="153" mass="17232" checksum="6CACB20718D20EB1" modified="2025-10-08" version="1">MARILSQEEIAVFKELFDSYDDDKGGNITVQEFAKVMSNSPGQQPTEAEVQQIIKEVDLDGDGTINFNALPPVADPADEYAKAWKEFEPSLKGSITQAQFRQLMANLAEPVSDVEVDKLVNNVDGEGKISYKDFDHFMKHRNTESDILQEYEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXS8</accession>
    <name>A0ABR1UXS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661182.1">
        <property type="nucleotide sequence ID" value="XM_066818994.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052054"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF163">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="451"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="49"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="491" mass="53094" checksum="2D2E81BB7C5B96B8" modified="2025-10-08" version="1">MDETNPLLPDTTAERVREIEDARDDIVDFDPSGDAENPLEWAPGYKWAIVGLLAFMAFTVTFTCISVVPIASRITTDLGDPRKSSSVLLVTIWELGEAAGPLLMAPLSEMFGRYPVINAANVGFIGATVLAALCQKAPLFIAARFLTGLAVATNVLNPAIVGDMFVTEQRGSAMSLVQLAPITGGAVGPLISGAMAETIGWRSVVWLSVGLACVCEAFLLAGFKETYKVPILRRKAARLRHETGDKALRTAFDLMDDERSTRKLWDAMMRPVVVFADSFVLQLICLFGAMTFSYFYIFSTTYPDILVQTYHLTPAQTGLAFIPLTFGSIVGTLVCNALLDRIYIKLRDANNGIGMPEYRLPIVIVGAFALPITFTLYGWAAELRLPLWVVLTSSGVFGFAMNFAFMPVFTFVVDAFGLYSASAITAMIVTRCVAATFLPLAAVSLMKQLGAGFGCTVLGAVGLAFAPIPVLIFFYGPAWRQHSKYTKGNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXY6</accession>
    <name>A0ABR1UXY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661242.1">
        <property type="nucleotide sequence ID" value="XM_066819054.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052114"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046498490" description="SnoaL-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="33"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="177" mass="19485" checksum="5D2CCF7433513B39" modified="2025-10-08" version="1">MQFSTAFIAAVASIPMSLAATTYGTAALEPGLYEAIHQRENVLAYTLDTKQYNRLGESMTNDIVYDSRPLGPNYGGLSVGLKQTTDNIRAAFAGAKVAHHVSNAIIVPQKDGKAANVTTYIVYSRWDPAALNDATKTFRIYERCDDYFVVDSSDGNWKLKYSLVTNLAPKVERPYFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UZ11</accession>
    <name>A0ABR1UZ11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome biogenesis protein ALB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661663.1">
        <property type="nucleotide sequence ID" value="XM_066819475.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052535"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8063064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12219" checksum="B144ADA83252D896" modified="2025-10-08" version="1">MPSVKNPNGPSKNRQAAMRASAKKKAQKSSAAGQTRILKSDARRGAREGILPTSGPNRALSAKKQRKLDKARAHALKRKMEAEGEVEMKDAAETTDSKELKEQMEMDAETIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1F4</accession>
    <name>A0ABR1V1F4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661774.1">
        <property type="nucleotide sequence ID" value="XM_066816082.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049142"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045869960" evidence="2">
        <location>
            <begin position="21"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="441"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="600" mass="66207" checksum="3503E39121142268" modified="2025-10-08" version="1">MHLSSVVSLLLVAAPATLLASPIQQMQNQQQGQMSKNGQVAAGKNDQQGQMSKNDHEMSQNSHAVAGQDQAVTGRDKKQQGQQSQHSRNGQVAAGQQGQQQGQMSKDDYGVAGQNRAMTGQKQHQDQQSKNDQGTMGKDQAVAGQSQQSQQSQQSQGRVFVGQNQAVTGQQKQQQHGDQSQGRVVVGQQKQQQHGEQSQNKHDTTEQQKQQQSHESQNSQVASGQKKQQDRQGRQSQGHVVAGQNRAIAGKSRAIAGKEQQSHDQVVAGQQKHQQSQQSQNKQSQNKQSQNKQSENTKDSASQKKQQQSQQPRGRIDAEQQKQQQSQQSKNDKVSANQKQRQGEQSQQSQNNKVTSGQKDQQGQQSQEKSIAGRNRAINGQNRAISEKMQQQQSQQSKNDHATTGNKEQQSQQSQGQQSQGQQSQGQASDGQNRAVNGQSQAVSEQKQHQSQQSQQSKNKQAAAGHEEQMQQSQDQAVDGKNQAVSGKKQSQRRAIAEGQQKQQQQKQKLPMILGMSRVKNNVDQSKNKNKANNVKRHHMDLGGYFANQKHPDCAAKASKCKNCGDDINCNEDPDCEWCWSCVWTSTPDAAYCNMTSSRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1N4</accession>
    <name>A0ABR1V1N4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661817.1">
        <property type="nucleotide sequence ID" value="XM_066816125.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049185"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045712614" description="Carboxylesterase type B domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="2">
        <location>
            <begin position="21"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="532" mass="56166" checksum="D998C9388C4B2E22" modified="2025-10-08" version="1">MLLSRQLLLSLAAGLAAAVDSLVDLNYTKVQGAALANGATQWLGVRYAAAPLGDLRFAAPIDPPADPRAPCASDFTMKPNKRFTVAEDCLFLNIFAPSHATATTTKRPVLYFIQGGGFQSNSNANFNGSDLAASGDIVVVQINYRVGPFGFAQSKEVQAGGSLNNGLKDMVQGLQWVKKHIAQFGGDPEQVVAAGDSAGATGVALLLAAFAEKDPGLFRGAIMESPSVATLRTLAQGQEQYDCLANATGCLGAADSLGCLRGLDAAALLTEQCQFNPHLDGDLVKTPMLDAFAKGQFLRVPVIAGACGDEGTKNVPKDTDTVAAARGYIQDQASGALSNSSLDLIEKVYLDAPQPIFAGAGRLWRQLANAHGDFRSTCITAALVDGLAAGGINQTYSYRYAVRDPEQDALGFGAYHTVELNGVFGPNNTDGAPPKSYRAGESNAGIVPVTMAYWASFVQTLDPNAMRATGAPEWRPWTVAGRERLRFETADMGMEAMNDTQRANCDMFGPMLPAMETPLDKPGSVVLTRKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1S6</accession>
    <name>A0ABR1V1S6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Inositol monophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011877</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661884.1">
        <property type="nucleotide sequence ID" value="XM_066816192.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049252"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="358" mass="39487" checksum="11A8757817263A2A" modified="2025-10-08" version="1">MDKLHLSKVRDALIDVAKDAGQWVLEVNEKHLKSITKTNSKYLLLKCYIHAKLLTHPLTGTEFVAKTDKAVEAFIKKQLSLWYPLVAFMGEESYKAGQTIRDDIPTFVVDPIDSTSNLVHHLPDVCVSIALVLGNQPIIGVVYNPFNDELWAGHRGGGAWTEKGNALAKMLPLYAPPFELDYLNGLSRLTGACIGVDWGTDREGPEFDLNLKVFTSLARTQWTGGKFVNSLRCVGSAAIAICRTAAGQQDMFWECGAWAWDVAAAWCILREAGGVMVDGGVPGNWNPPIDNRRYLAVRPAFAGQREAVEEFWSVLGDSRSQYGPPSKEGKYMEVFSTEDESTEGEFTEVGSSEGEFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V223</accession>
    <name>A0ABR1V223_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="12">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_011980</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661987.1">
        <property type="nucleotide sequence ID" value="XM_066816295.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049355"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF134">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="287"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8065233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="323" mass="36965" checksum="46E01C213787999F" modified="2025-10-08" version="1">MASSSQAALYESWPVPTLDRPFGIHLWPIFNKAFEFVVGYPADDFRFEAGRTPMSTLKETSIFVVIYYIIILGGRELMRKREPLKLKTLFIIHNFYLTAISGIFFAICDHDGGWTQPLVVLYYLNYLTKYLELLDTVFLFLKKKPLTFLHTYHHGATAVLCYTQLLGHTAVSWVVITLNLTVHVVMYWYYFQSARGVRIWWKEWVTRFQIIQFFIDLGFVYYASYTYFTSTYFTWMPNHGKCAGEEFAAFSGLIVLSSYLVLFISFYFATYSKDGKAPSARKAVRRMSQAPVPDAHTVASASHGSIKATGAKANGGSTRSRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V232</accession>
    <name>A0ABR1V232_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662015.1">
        <property type="nucleotide sequence ID" value="XM_066816323.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049383"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="65" mass="7845" checksum="59151E6F3316D43A" modified="2025-10-08" version="1">MESHRAWMLGMLRKNTPEAYRKLSRRRKPNQYSVHFKLRWNLVTFMEQQQYSDEGIWGSLGESSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2B4</accession>
    <name>A0ABR1V2B4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012074</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662080.1">
        <property type="nucleotide sequence ID" value="XM_066816388.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049448"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF25">
        <property type="entry name" value="ABC-TRANSPORTER-REGULATING TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="670"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="745"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="770"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="785"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="909" mass="101365" checksum="A49639BE15B8B5B9" modified="2025-10-08" version="1" fragment="single">ISRTPTHLGHDGSPSSRSGGFHVHGMHPPQLANPPPQIFGTYLHDGMPVMPPDLQMGFDPSSLMGDENEAKRRRIARACDMCRKKKIKCDGKLPACTHCINYKTDCVFTQVEKKRNPPKGAKYIEGLENRLGRMESLLRLSGLLGEDDEATDLGTLEKRLAEKAQQSRQASQAAQSNPTSPSQATSGQNDAASTPQSSLTSPEPMREDDRRRPSIAPSEKQKEKEKEKEPEKKKGDDVEALSELMCSLVTNQSGETRYIGSSSGFSIFSPKGIQWVNEKTGDNSFSEMISEVSIDDHKWNHWKPEIFSDLFHRRVFRPLPPKPEALSLLKDYFENFNCMFPLFHQPTFMHLVERQYSNDPYEGSGWWASLNVALATAHRLRVMSKLVPEEEDSKAWAYMKNAMAVFPELTMRNTDLLSVQALCGMASFMQGTPNPQPSFLLIAAAIRLAHTIGLHKRGSGFNLNPVEIEQRKRVFWIAYMLDKDLCLRSGRPPAQDDDDMNVELPDADPEDNIGNIPLADGKGKMNLFRVMCELTTIESRVYKRLYSVKAQKLSEGELLQTIGELDKELEDWKDNIPIDFRPEHDIKASHTPLILHIVMLHFSYYNCMTTIHRMSVHRGYWTNRLSNYAIQGLNTKPLNPRVFSSAALCASAARASISLLKYVPQGDYQVVWLVLYFPVTALVTLFGNILQNPVDPRARSDAKLMNMVVTFLSTLGHEAETGGVHRMLGVCSEFERIAKVVIDKMEKEGPARRKRKSHDPARPNPSNAQTTTTPRPPSSAATPKSHFNQGYGQSSPGTFSTSNQYSPMNTAASSNGQAPRDGQDGWPQDYPSTGATYDTPDFNNFAELTGFGQALPSPPMQNPVGGFQPLLPQDLWQLPTALDWEWAEISGGVLPGFENGAVGHHPGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2Q7</accession>
    <name>A0ABR1V2Q7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="9">3.2.1.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_012204</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662210.1">
        <property type="nucleotide sequence ID" value="XM_066816518.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049578"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF1">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE I_II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045201059" description="glucan 1,3-beta-glucosidase" evidence="11">
        <location>
            <begin position="21"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="12">
        <location>
            <begin position="92"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8065457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="396" mass="43311" checksum="73579760E486CE60" modified="2025-10-08" version="1">MQLSSLLAAGSVSSAALAQAASLKPRTNYLDWKTFKGDGVNLGGWLIQEPFIDTEWWSANCGVEVLDEWTCCANLGDQCGPVFEKRYSTWFTTADIDVLASGGLKVLRIPTTYQAWIDLPGSELYHGQQLARLREIASHAITKHGMHVILDLHGLPGGVNNQTIGERVGGLDWWYNETALAWSMKTVDAVLDFIQQSGQPESFTLEPVNEPMDNPDDIGQPSSLSEKASAWLLKYYRAVLDRVAAVNPRIPVMLNDGFKGPGYWAGNFTQDQNIVFDVHYYYFNGRPAGSNNVTEMICGDAQAAGGGQSEDHKFPVFTGEWAIETLYNNSLDARKSILSAGLAAFGKHTKGSAYWTGKVVSDEAVAGQGTKQDYWSYKGLLELGLVDPESASGFCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2S1</accession>
    <name>A0ABR1V2S1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012224</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662230.1">
        <property type="nucleotide sequence ID" value="XM_066816538.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049598"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="14"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="180"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="212" mass="22824" checksum="58BC942B0D374AB1" modified="2025-10-08" version="1">MLATPLGPDAPRATILLVHGWPDLGMAWRYQVPYLAEKLRCRVIVPDMLGYGRTSAPADPAAYTLRNIAAQMRALVAHVLGTDKETVILGGHDWGGAAVWRIAMWCPDLVRAVFSLNVPFSPPLRRLVEGEELVKRVPSFRYQLQLASPEAERIVDASPARLRAFINAIYGGTVVAGGGGGSPTTTSLSSRSARRRASSRARSTPGSGPRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2T6</accession>
    <name>A0ABR1V2T6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662254.1">
        <property type="nucleotide sequence ID" value="XM_066816562.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049622"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="215" mass="23959" checksum="AE25D3E3459E9DB0" modified="2025-10-08" version="1">MYSLWKATSRAVATYASSQSASVGSEWRGQRAQTINYLRHRGQALLEACHGRAEDLTGTNLEEQLDRLLDVEDEAEFELRADRLAGMFAFCFAAMRLATEVLRDDMHDYQIGLPGGSPCIGWDEMAWQRSTAESLGLEAYARRVALVEILMEDAQLTEMGPPFRPGLGQGWSFLRPVRYLAAALVGSEIPIQELELTVKNMSKACRARAMGKIHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3E8</accession>
    <name>A0ABR1V3E8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662220.1">
        <property type="nucleotide sequence ID" value="XM_066816528.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049588"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="361" mass="41023" checksum="814321712C3F46F3" modified="2025-10-08" version="1">MARESSGRDNSQDRNEDSSDRDRRDRHDRREYDFRRRDESAASHTNNGVSRRSRPNGGRRSDSLFQNHLHALASAHANRNTGQKTVDKYAKKVELTLKTAQERATIDADVRLGGPQDMFETALTADKNRLRAQSPLLSSVFQRHVRYHRDPSRLHERRQPDTSNTEGGDVKDNPRPSQPRKIESQVQTPLATPATPTTPAVADPTYSTCRICKGPHPPSRCMQTDGTTGMLKVCPIHPHKENHYWDTCPSLLKYLTTPELVQALWLWMVEGRAGMPPFYTTMVDINEMTRNMTFHTYYEVLRNTRNYEHTPELPSHFAEKNRATKTGYQTVGGLEPEHGDLGSLVAWLGSEAEQSAHRTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3S3</accession>
    <name>A0ABR1V3S3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662588.1">
        <property type="nucleotide sequence ID" value="XM_066816896.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049956"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="61" mass="7021" checksum="E71680BC7D035C5C" modified="2025-10-08" version="1">METREYRNYTKRIHYTATKFLEPASTMKPLVAFSVVALATLSNALIRFQCSQLVIERLDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3X7</accession>
    <name>A0ABR1V3X7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA repair protein rhp9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012643</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662649.1">
        <property type="nucleotide sequence ID" value="XM_066816957.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050017"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17745">
        <property type="entry name" value="BRCT_p53bp1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047249">
        <property type="entry name" value="BRCT_p53bp1-like_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047252">
        <property type="entry name" value="TP53BP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15321:SF3">
        <property type="entry name" value="TP53-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15321">
        <property type="entry name" value="TUMOR SUPPRESSOR P53-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="5">
        <location>
            <begin position="744"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="290"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="759"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="995"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="381"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="477"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="556"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="607"/>
            <end position="617"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="762"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="995"/>
            <end position="1004"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1051" mass="114272" checksum="75EA29DDFA890CE4" modified="2025-10-08" version="1">MARQKKPARSIAKAEERAYKGDNESQDSQLVMQNMHSLYGIGQQQQTTPGANASIVSTSRPQPPPPVTRATVIATEAPLSSERRQSTTTTNQRQFKSAIGSNTLADDHASLPKLRPTPALKKTMEDGSQSPTQSNEGRSYEQYREIRGEAFASSQLKPADSGDRYESQRSRPDSDHEHATLHEDETGAVNFDLGQFGPAAASHAHNLNDAETDSGSDDDERDRYSSVAPVSQPRRSSGFLPPPFVRNSSTGVPPPETPALATRLCHAGGTAEPLMPSSQLFANTQFTSAVKKVASPTSSRPSPELNPNTISPNPQLISSPLRERGLRTSQLQVETSSPYVPPPSSGPVPTTQDPYDAPESPYSKPQRTRSVPEPIRDYIPSRSSPAERQTSVGILDEFGAINSDSDVDQEIRKRRQRRAKRKQEEATRSLKAIPISRPASRSEELIEVPSTNRRKIASRSADQLTYEDIGEAHETVADSQDVATKNTEPSKDTASQKNRALNSAAQETGISSSDIPLLPRVQPINTHGSRDLIPETSPAGTAAAEPKGPSPPILSNVPTEAASTPTLPPPKRLKRSEIKETDEIVMSDPGDQAKPMGSSPPIPSTAPLPSSQSSQPSRRSDRLQNVATPQPVLSSMPPPNVSSSTTPYTEDEEGSEEPPKNNLSSPAAAKVHRQSRPLSAMKTYSPARQRTQRDRARKEPSRLARQSSVSTDELARPSPSPASIAGHTRGSRSFRAAKDTSLQFPSGIFSGMIFVTTIGSSDNDKKKKTEAQKREEAEKEEKKEKIEALIRKGDGHIMNAGFHDLFEDQSSVVPEASSKISASCLNLTQEAANAGFTALITDNCSRKAKYMQALALGLPCLSWNWISACNAKGSLVDWLPYMLCAGPSTVLDGAFKSRDLPGYEASSAKLSETISQRPKLLSEMSVLLVVKKTKTQKHEKRCTFYAFLAHVLGANLERVNTPTEAGDLLRERDEAGSPFDWVYPDGDDTIFSVLTNGPPTQVSNTKKRKRQSTTNSGSFGTPLRNMPRILTDELIVQSIILGRLVEEREMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V422</accession>
    <name>A0ABR1V422_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012689</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662695.1">
        <property type="nucleotide sequence ID" value="XM_066817003.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050063"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046816874" evidence="2">
        <location>
            <begin position="21"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="379" mass="33691" checksum="A3010C929BFF34F1" modified="2025-10-08" version="1">MKNFGSALLLLAASASMVASLPAVERPGDVIAARAPFEQAMHVRSSPELARRKKDKDAAAAAEGAAAANGTAPAAPAAGKGEGEKKKGKAAKAGKGAALDQGAAAANGTAPAAGKKAGKKAKGAAAGAAAGNGTANAGKGKGAGGAGAGGLEGLLGGLLGGGKAGGAAGGAAGGAAGGAGGLGQLLGGLTGGGAAGGAQQGGAGAGGLGQLLGGLTGGAGGAAGGAAGGAGGLGQLLEGLTGGAKAGGAAAGGAAKGNGTAQAGKGKGAGAGGLAQLLEGLNGGAAKDKAGAGAAKDADKAAKDAQKEADKAAKDAEKQAEKDAQKEADAAKTAQKEADKAAQKDAEAAKNADAAAGKDAAAGADAGKDAAADKEGAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4E9</accession>
    <name>A0ABR1V4E9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Peroxisomal adenine nucleotide transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_012823</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662829.1">
        <property type="nucleotide sequence ID" value="XM_066817137.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050197"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF2">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="14"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="130"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="234"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="270"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8066076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="484" mass="52164" checksum="2162B28A2C667468" modified="2025-10-08" version="1">MSATSSRTNLHDILPALHHALSGATGTAIATCTTYPLSLVLTRLQAQRQLAREGVLPAEEKYEGIIEAFSRICAGAEGKEDGEGWKALYTGLTQDVTKSVLDSFLFFLFYELFQSRLRGPRSSRGNSKGPGVLAELAVGVAAGACSRALTTPIATIVARKQTAALVDDQDSDATSAADLSVREIAAAIRREKGLAGLWSGYSASLVLTLNPSLTFFLQEFLKRGLLSSDRWDEPGSGLTFLLAAVSKAVASSVTYPFQIAKSRLQVSTVPAEPEPEVKAEAEGEKQENGGGGGEDAARDVEKEVEAKLSAVRAVQKLARRSIFGTLVTIAREEGVAALYDGLPGELLKGFFSHGTTMVAKDVVHKLLFKLYLFLAGVLREMRLRRGRASQQIQRMVSPTAKKTNNYSMYDDDVGSGQDLPRALQFRNDFSEIARAMRMDRDTPKRPWGWFLSGGGGSKSPNSVLDGDAAGFIVNVTDPSQRKIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5W1</accession>
    <name>A0ABR1V5W1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PHD and RING finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013342</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663348.1">
        <property type="nucleotide sequence ID" value="XM_066817656.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050716"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047157">
        <property type="entry name" value="PHRF1/Atg35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618:SF20">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="173"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="353"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="490"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="35"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="514"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="716" mass="77463" checksum="4560F02EA6F89336" modified="2025-10-08" version="1">MADQCIVCLESLDVHPLVVPPLQQSDPDVVDVPHDTAGAPAAADASTSASDSTLAVSVAPAPATAPTPAKATSAEYDAVTTSTSTPDGFVSDEDSKIAEIEICGHILHDVCLRQWTGKANSCPICRQTFNSVVVYDRVGGNKLDSYAVADKKQIAEFDAPSWLAENPEPEEPAQPCPICNRSDQEDILLLCDSCDAPYHTHCIGLDHIPRGHWFCMECADEGAALAAAELVDPESGLSRLAGSSDHQSDFMPRTQATLRRERQRARSAEWQGAWGEIAGRVWDVLDIDLNNPEEDEALLNYRRVERRRGGTRLGNGSYQRSEFERWQQRLHIADRLGSLDVFTNGIPQGRSLARSVRQTPPPPPPPQETPEEKEAWGALEMAKKALGTDRSAEATTPNPRKRRKSRSTTASPREPAPEPERKLKRPRTRRVPHDSAEASSSRQPQAGPSSSSAAPPSAAVTLPTQPATQAASPQGTAVPSFLSTLLKEVELSTPSDDENVRTVLGVSKSNNEHSSPASSPSPSGYSSPRALSATPPPRGISERSASPLTLTSRIEPIYPPANFSPNRNGSPSRMCGSDSSDSESKPRRQQHSPKRNGTTSLEIRHPRPRRQHTTPIKTNVAGRSPESSPTRGSPTRIALPLETKENISAITKAALKPHFRAGSINADQYTAINRDLSRKLYMQVPDEGLDHDTRLKCETLASQEVAKAVADLKTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6T7</accession>
    <name>A0ABR1V6T7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_013640</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663646.1">
        <property type="nucleotide sequence ID" value="XM_066817954.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051014"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF1">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046184798" description="cellulase" evidence="9">
        <location>
            <begin position="17"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="10">
        <location>
            <begin position="17"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8066893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="391" mass="42156" checksum="C9668C2C5D5CDF44" modified="2025-10-08" version="1">MRAFVLSSTFAGAALAAANGPYAQCGGNGWAGESTCVDGYTCTFSNDWYSQCLPGSAPAPAPAPTTSAPTTTMVTSTKTTAAGAPTSTSSGKFKWFGINQSVAEFGEKNLPGVWGKDFYFPRMRLSLQGYNAFRVAFLMERLVPDKLTASANAGYLANLTHTVDTITKAGAYAILDSHNYGRYYGNVITDASQFKAYYATLAGAFKGNEKVVFDTNNEWHDVDQQVVLDMNQAAIDAIRAAGATSQYIFAEGNSWTGAWHWNTTNDNLKALKDPQDKLVYEMHQYLDADGSGTSDVCVSGEIGVQRVVGATEWLRANGKKGIIGEYAGGANSQCEAAVKGMLDHMLANTDVWMGAIWWAGGPWWADYIYSFEPPSGTGYKYYNSILKAYAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V836</accession>
    <name>A0ABR1V836_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_014075</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664081.1">
        <property type="nucleotide sequence ID" value="XM_066818389.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051449"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF18">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="8">
        <location>
            <begin position="6"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8067328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="272" mass="30252" checksum="71161A3071C25445" modified="2025-10-08" version="1">MPDSMSIGKYAKAPADASRSPCPVVNALANHGYLERSGRKIYVEDLNAAMGHVGMSPLLGSVFAVPTYFEYHDPALAYTRKPVSTWQRAWSVIGNPYSYFDYFGCWKEKQVTDNGRKYLNLVDLASHGAIEHDISLSRRDVGQAEGNNNPQPDLIEEMLESSLDGKSLTIDDLAAFIKARIKRQLKDNPELVYGPAEHQVNCGQIALMMGCFGDGKTIPVSYVKAIFEDERLPLEEGWTKRSWWTMGLAEFFGAVRNLVAKVDVNFDHPAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHK8</accession>
    <name>A0ABR1VHK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010926</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664531.1">
        <property type="nucleotide sequence ID" value="XM_066815241.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048301"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972:SF1">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972">
        <property type="entry name" value="MONOOXYGENASE ASQM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="162"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8070723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="261" mass="28412" checksum="E35F8E47B3E1B7CC" modified="2025-10-08" version="1">MPVLEFADGTTASGFRLVVGADGAWSKVRSLINDVTPQYCGIHIIESRISPANPVYTQVQSRVGKGMMLIGGPNKMITLQNLGDESYRMYLGVRVPADFATDGQVDFSDTDAMRTMCLSTAFFGDDWADEFRGYITNATDFRPWPLYHIPPAAVAWPAVPGVTLVGDAAHLGPPSGEGANFAMTDALYLADKLAEHGDWVDSDDARDRAVRGYEVEMFERGAKLIQRGVDVTEVFYAGDAPRPTVELFRGKGVPVLEKKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHP7</accession>
    <name>A0ABR1VHP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664210.1">
        <property type="nucleotide sequence ID" value="XM_066814920.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047980"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="202" mass="21572" checksum="F785FB66361DB1C6" modified="2025-10-08" version="1">MENTTQSQHYRRQALLFQGLTAMQTQLDEKRRRKRREEKHRQQEQQLEAPDPPPQMPVNRSNPPSGASPSSSLAATSPTSPTPRATSPSSPSSGSMRAPPSAQAQEGIPPPSDPGAVPVFQPGPAPAIPAPALVLVPGPDPSHPQNSQNSVSYSPFPKPQPSAANDGGGGNPAGRSYGLSIPQRRSSLRSRRFPLHHHYDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHZ4</accession>
    <name>A0ABR1VHZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664575.1">
        <property type="nucleotide sequence ID" value="XM_066815285.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048345"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF55">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="73"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="296" mass="33765" checksum="29106CA6AE777A16" modified="2025-10-08" version="1">MAPPDSSPWDALKGWHNGTETLAINNTRVRRLLTRAAVRLTTLFLPTSRCRDGPCVYISKHLLVKTGPLVHLQEAATMNFVAENTSGVPVPKVHCAFLHEDHAYIIMERIQGDRLSSDPAALTKILEQLRRIMQELRSLQPPGDAGVQSCTGGSLYDARNTRAFPRMGPFQTVHAFNVWLRDSLEPSEKKPENWHEEEQDWEDIREMAGLQDGPWPAPVFTHGDLNPSNIFVRGDEVVGIIDWETAGWYPVYWEYTSAWTVSIDNEDWQGTIDQFLEPHPAALKMERTRQRWWGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI27</accession>
    <name>A0ABR1VI27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_011088</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664693.1">
        <property type="nucleotide sequence ID" value="XM_066815403.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048463"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="144"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="43"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="635"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8070885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="782" mass="87608" checksum="E6E7863E97830B0B" modified="2025-10-08" version="1">MRHGSNTGYQTFHCFSVPHACFHTGFHFKCAYQKKGTHSLSKVSFYPGRGESTEDRQFRHPRQRADRKPNGKPPRVNKENAVSPSLTTSSNTLDWDGDELALLADVETVKEGVRAFTQHFFQLGFIATEDFLLQVEREPGKIGAFLLVSILSISARFNRNYEAAQKVVQSYLDCAEKLALRELYQQPITLERCQAFFLLSIAQHGMGDTSRSNINMGIAISMATEMRLHREETFKLITEDSTRESRIRAESARRTLDNLHSGPYKPVLLAAGDITTLLPCDEDEFRCGEFQVKPRAALVGTPPADLNPTLTTLKSRSLFATLIQTHHIWGTVARRAVANKKSSYPNDTGSDYAKIATQLAEFEGNLPKNQVYDDLFLAGYRKKNEDLAYLSACATLRLSNIVLRKAYLGGYSMIRSLKGHRSGLGVHILHTITNELFDNVYRLYRQICAQFDDSDRPLEEMVGSQMAVSEASSHRHSNLELTRSRRSVFTVAACSYRTSSSTPGVSIRSTSFSYQFTKRLIVYQNSESKKDEPPKMMYDRIIGILEEAQAIWPLASSWLTGLKSWMGGPDTGGVYEGVFMADGKNPLPHAFLHPPVSTPADKMTGLLSPSFVHGRVEPKQHIVPVVHTEPAILPPLQSSQSISGEPPSLPPPPLLDYTSPTQQQQSPTQYHHPQYNSYSSQMPDYVKHEHQQQQQQYEGMYALHHGQHNAGTSTAQIPPQVANTYDQNQAFIPDFNNFMSTTNDGFNLQLQQLMGVHWNAPDATVPLCNQHHLTDMSTQPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI83</accession>
    <name>A0ABR1VI83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664753.1">
        <property type="nucleotide sequence ID" value="XM_066815463.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048523"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032852">
        <property type="entry name" value="ALKBH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573:SF4">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="551"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="711" mass="78388" checksum="C8B862F5460A68E7" modified="2025-10-08" version="1">MGRTTAKRELAQLGPILNTKRRRVDVASDSASESPVAEIQQLTPSRSLSHPPSFPEQELASAISNATGATNDASNIPVESNDIHVCKPEACDRPIAFADKRAQIADALPFNRNHEGCFYTSKNILKGMVIDGAASPRATITDSVIVTTVGGGRELDAASGQMLRTKDQDQGCRKYGRVMDAFEKRLPVSVVIGSKNPSYPVKPPRSFCFMGFFLVTYVWAEKTVAVDGSLVSEYMARLEKIDPHAKSWWMPAGHDTEPVPVGEFQCDGNSCDSCGKYSKTVYTEGWTCLSMSCPEHFGFERPLNPDGLVYNEAFLLERHDNRDILPLPPVIPTLPVANETSCGTESEFKKGIVCPQCGLCSRRVYWWGWACENESAGCGFTHMVPFTNYPLSSVKDECTVMNTRRQLEHIDASIEHRTTSSGGYSIEMYGFPNSEGLVGGAVAVFRATPETCGMPNGPDELYLNMQNEDLRLRRNPARAKGSRREELTSHFAFNYGAFYKFGVFVNSVGFKDAPAPILAGLAQLDWAQSLGITHLIVDRPLGKSMSLKSKKFNELLALGYFEESTISYHDDGEKELGPTVATLSLGSPAVMRFRPKRKTQLGQEGRSKRGDKPSVISFVLRHGDIVIMHGTDIQRDYEHAVTPCGKLRFALTARFVRPESIESHEERQRAVENGQVPEGIASMAYKGYEEAAADALHTPVEQQALHNLPHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI91</accession>
    <name>A0ABR1VI91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">ATP synthase subunit d, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_011152</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ATPase d subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664757.1">
        <property type="nucleotide sequence ID" value="XM_066815467.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048527"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008689">
        <property type="entry name" value="ATP_synth_F0_dsu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036228">
        <property type="entry name" value="ATP_synth_F0_dsu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12700">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05873">
        <property type="entry name" value="Mt_ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005514">
        <property type="entry name" value="ATPase_F0_D_mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161065">
        <property type="entry name" value="ATP synthase D chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0138">CF(0)</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8070949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="173" mass="19456" checksum="D2961476B9187649" modified="2025-10-08" version="1">MAARSAALKLDWAKVTSSLGLRGQTVASLQAFKQRNENARRKVQVLSEQATTVDFAHYRSVLKNQAVVDEIEKRFKEFKPATYDLSRQLKAIETFEVEAVKNAQATKEKVDLELKDLSKTLQNIEQARPFDELTVDEVAAAEPSIDEKTAKLVSKGRWNVPGYKEKFGDLSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIG6</accession>
    <name>A0ABR1VIG6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetyl-coenzyme A transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011239</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664844.1">
        <property type="nucleotide sequence ID" value="XM_066815554.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048614"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778:SF9">
        <property type="entry name" value="ACETYL-COENZYME A TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="527"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8071036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="571" mass="63065" checksum="47A9C8AD678695C9" modified="2025-10-08" version="1">MGVKTRSSKSSKPELIVTTSGRENGNTDGGNMENRRKNAPKQDSAQVTENLMARSEFSLDEPVPKTPTMNNHGFFELPKTDQRNFLLLVLLYFLQGIPMGLAHGSVPFLLKEHLSYGEIGIFSLAGYPYSLKLLWSPIVDAVWSPRFGRRKSWILPIQLLSGFGMLVLGSVVEGWMLTTGKAGGPTVWNFTGWWFFLVFMCATQDIAVDGWALTLLTPGNVSYASTAQTVGLTAGHFLSYTVFLAFNSPDFANRWFRSVPSDQGMMTLGGYLTFWGWAYIAVTIGLALLKKEEKTKNEDGIWDVYKIMWGVLKLRNIQTIIIVHLIAKIGFQANDGVTNLKLLDKGFGKENMALTVLIDFPFEIGLGYYAGKWSQEYTPMRLWCWGFMGRLAAAVLAQFTVSIFPAGGVTFGYMLLVIGEHVFSTFTNTVMFVAISAFHARVADPVIGGTYMTLLATVSNLGGTFPKFFVLKLVDYFTVATCHPPTTKVDASLLKAPLVTAPFTCAMQAEKELCVGGGGSCEMLRDGYYIVNIICVLVGVATFVMYIRPKVLHLQSLPLRAWRLSTAPSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJH2</accession>
    <name>A0ABR1VJH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665195.1">
        <property type="nucleotide sequence ID" value="XM_066815905.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048965"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF310">
        <property type="entry name" value="FATTY ALCOHOL:CAFFEOYL-COA ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="359" mass="37944" checksum="7987C28026B4EFFD" modified="2025-10-08" version="1">MPEPPAPVMAAQANFITGGLLLTAALHHSAGDATALETALSAWAQNPAAAAAASGSNNSSSGSAFTSYDAPSNDRGSLMQGTPPDSMAEFPEYVLRPNEKQSSLVVDETAPVAAADFQLPPMSGRIFYFSAAKLANLKREAAAYSTNDALCAFLWCQMTAARNPLSSFSYSSAMEDKVSAFTSAVNIRGRTNPPLPSTYLGNGSLPSMTDRLPVSELMAVSSEDDPAAPTTGPLQRAAAAIRASLQRYQSPTRVSETIGLLRSRADPSDYKQTFRAFLGPDVVASSWSDIRVLAEGNWGGEFGAPECFRIPGDDADGAIVILPRRPVEDGLEVVVGLETGAMGRLLESEEFRRVAEVRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTI2</accession>
    <name>A0ABR1VTI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665462.1">
        <property type="nucleotide sequence ID" value="XM_066813500.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046560"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="91"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="531" mass="59753" checksum="03DB48B1308F82B3" modified="2025-10-08" version="1">MRPRDVDDQFGEDNEIDGDARGRPGRKKRLAQDTSSKASKIRKTRHDPDDAAEVDEDANPPSDVAQVIVQVREVDRFCSIPSFPAASPPTPDVLLLASAVRGRLAVAQFRDIVKEWRGVNASSRLRHGGNRFQRFGRLIDGAEDSLGFAEFRLRIGQAGLAAELDATVSRGFKKVGGDKRKDKREELGWSEQRFEYQLAKGRKWNRICGNKFRGIIGFIFTTHRNAFGIPPEDFKKLGKQVTSKSIAPSQISDPGHQDLSKFCREFHGLLDDDYTQAICRAGKAFESAVVDSDPNIEFKWETLPDSPDWTTLPEPELLSYMQPYEPATTNVYRPTEYLDWPRPDAWPDKWAWPVNPLSEGVVGCEYCAERDCQCLTRYHKSMPSIRHYGCRGLGLQAVAQVSGRVVYKKNATIGWLLGKIIPPSVLNNPGRDRCVEFVRPDIPGEPVVCHLECLDSSNLFRLLNHDCSPVAQLTPRRISSQYVLAVVAKQDIIDGMEITISYTRKHYGLHCSCRTCEARKRTPLPNGKGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUR0</accession>
    <name>A0ABR1VUR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665897.1">
        <property type="nucleotide sequence ID" value="XM_066813935.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046995"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632:SF24">
        <property type="entry name" value="GALACTOSE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632">
        <property type="entry name" value="LD33804P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="37599" checksum="EC62B32CAC59BA03" modified="2025-10-08" version="1">MLPASVTRQPMKLGHSVGQRNDHSQNHVEKGREDDGSYAQGLALGWGVIEETQQENSVAALGTDVYILAGITAAAPNDTTFPSLQLVQAYSTESRTWRRVADVPMPLNHAHFAAVAGKLYVLGSLTGDGPFLPTVASYEYDAVADAWTRLSEGDMPEDSKRGAGAIGVWRDRFVIVAGGLFDNNPVTGISHTSANVSVFDAQTGTWLPGEGWPALPDGGRDHAGGAVIGDTMYVMGGRCNGRLNVKGDVFALDLTAAPEARAWVSKAGMPTPRGGLMAGAVGGKIYTFGGEGDEAHGAGPGGVFVEVEAYDTQTDSWEKLPSMAVPRHGTGAAVVAGKIYIPGGANHTGTGATSVFDAYSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUW0</accession>
    <name>A0ABR1VUW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665942.1">
        <property type="nucleotide sequence ID" value="XM_066813980.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047040"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="508" mass="54725" checksum="591630DA4D7B66C2" modified="2025-10-08" version="1">MVSFFGLKLGGDKKKKSGQTNDHRESHRESHRSRPATSYGPGFSKSNTNFNPQWNGSITNLGAPPVLGSRRPSVSSVKSARQKAWVNPLDVHFGKRDSTASAVAQPPTQGLRPSPLAKRETLAAPPLPTAPALPARSPLRNPPSPPRSINRSIRTTQELDSCFSIDKPVETSTEDARPPSPVSNRNATRVNETRPLYPGVFGSSSLPSPPPSASRTSDDVSRSSAGTWGEPVIQNVQAKRETMTVGALRQRSLKMKVERPSKTDSALPPPRPKTSGGYESRRTDRRPGALNLDLPSRPLDSGPRSPTFGRPQAPMDFGSEPSYKIDQPSKSNNKDFSRRSRHYYTHSAVRASYSSSVYDSPPQSPESPVIPLSGPLACPRPPAAAAKLPRQPSEVSEYEYDLPDWSALAEDGPQSGQGSATRNWPLSSTGGTSQEPPQLPGPRVDSPFGIPSFSRPWTGANARPGTPVKTTEITITTSLRTQSPPKTAPIYGLRNPAIVGDDFGTGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV95</accession>
    <name>A0ABR1VV95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2-amino-3-carboxymuconate-6-semialdehyde decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Picolinate carboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_009826</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite metabolism; quinolate metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.45" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666103.1">
        <property type="nucleotide sequence ID" value="XM_066814141.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047201"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01292">
        <property type="entry name" value="metallo-dependent_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF27">
        <property type="entry name" value="2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="12">
        <location>
            <begin position="39"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8075163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="441" mass="49037" checksum="9748AE22E85371AE" modified="2025-10-08" version="1">MAPSKISDYEDSCCTSTGCVTTAKNAANRPVDGSSLYRIDIHTHIMPSSLPDLSSYPTNSPTDPWLSLRPSKSGKSDEIDMYVGDSFFRTVEPNCIDAETRIREMDAAGVDVQIISTVPILFFYDEPAEPVTVLARALNDHIAETCQRYPDRFVGLATVPLQDVDESVNELERCKGLGLVGVEIGTTVGDMNLDDPALEPFWAACERLGMVVFVHPLGYALPKENKKRWSKYWGSWLVGMPSETALSILAITGSGVLLRHPRLRLCFAHGGGAFPALLGRIQHGYDCRPDLVAVNSGGVCPADHVSQGAFWVDSLVHDPDLLEFLCKKIGSDRVVMGSDYPFPLGEVPVAGKMLCAEDQLSRFLTWEQRANMLSGNAIKLFNLGSKFERRFQEKLAGFQLDLQPAKDTPAKSKDTSMKKLWWSWSTWRCNRWWQTRRTINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWI4</accession>
    <name>A0ABR1VWI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8004 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010257</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666534.1">
        <property type="nucleotide sequence ID" value="XM_066814572.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047632"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058317">
        <property type="entry name" value="DUF8004"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601:SF2">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26013">
        <property type="entry name" value="DUF8004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8004" evidence="2">
        <location>
            <begin position="397"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="624"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="865"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="865"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="915"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="954"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="985"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1015" mass="111230" checksum="AACEF78540013AEE" modified="2025-10-08" version="1">MSGRSAYARKIKETKASEKGGVATRGRAKSAGSSRSSERDDATISDYPILHGTGYGTTNARFLKFSEPIREADPMQFRGELTNFSNQSCGSQNSGGLGGRRDGMGYQDHMQDYAYARPRKPTIRTEDVSGIERSGLRSAIDKRSDGVRKGLSKALGFAKKSKKGEELRPQLERRTSFTESIRLGMYVAATVIDNATIAVSSGNTRDQAVDRGWQASAALEQAAQGSRTMGPQWRCSHLFGHRGQSPKANPSFRLSSHIIEATESRFLVTLLHEGSTDEDIYMSHSPDGAPPMLQKHGMNGNQTRSGYGMGRNGQPTPPMSEDATLADADGQISYEMYFPTPPNMNRLDVHRHAITTRNVFALLYHASLVGLSLHQALSDLHDRLDTYMPPEADNVGTILNYISARGIDDARNDPETAVSLLAWSEKPEVRWEEGWREAFLHSAGMYSRLEGCVDFKYITPITRALLERACLECQLRVQAAEERLCDFGYGDTWPSSGPITTGPARAAADRLQQFIKDHYIGLYGCWPPPSSGATTSDGEEMWLTRNVAQTLQRDFGALYDYLVNRDIIWDESETRSSRKWMMVSESGNRAFDPDTYDLPLTDMLIEWDNRLRFPHIPHPYPLVPESISPTAQSGSANSWKSKKSDKDKDKNNNRGGGDERILERRVQLAYTEATNIYILGSDLVPSLLVDAFVRFEKGDQVGVVDPSLARRGRWVLIYAILQTLASVSVDAPNVRYRDDVAYHLSPRLKGTKTPPWKGVASPPPRPRMSSHIAVLLLPRSNPYRDFPSPPLGTPATTASRGSGWHTGRSSTATRSNWSSNTSVDGPPTTWGGSSAMSAVSDDDYYHYSVNVRVLTAAPARRPLHMVEEEASRDGNKSVRSYATFGVPPSVGRVDESEDSAASSSGEVTATGWPTRGQSIRSGGNANNDGGNPIPPLPLPLGASMAGHGGFLNLDDSPPQRLPSRSPRRDHPAPLELRSSSRTGSRRGGAGGGSSDGMSSIIRDLDFMDVIDDHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWT2</accession>
    <name>A0ABR1VWT2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666661.1">
        <property type="nucleotide sequence ID" value="XM_066814699.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047759"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="66"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="369" mass="41113" checksum="7483CA4BB74AD91F" modified="2025-10-08" version="1">MQGFESAFPTVAEVVTNPAFPTALWHFEPHQSGLLPVAADRGGPIDICWEVHGDGPIKLVLICGLGFPKWSWQRQTLHFGHDHGDKYSVLIMDNRGSGHSSKPFMRYSTSEMARDVLEVIDHLGWTEARQLHAVGISMGGMIAQELAMLVPERLASLNLLNTAARIENTTSFAEDMSRRITMLMPKSFERTVTFAASKIFAQAWLDEPDECHIPDVHTTPRVRPPKQPAPHDPVLGNGNLETGDPPCPDNYGRFRTNYERFAAQEIHKSRDAEGYTKKGLVAAGFHWKSPKQLKELADRVGRERILVVHGVEDDMIPVPHGRKLIEYLEPAEGHIVEGMGHAPVVEKTEWIHGVLEQRIAVGEKLSGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWZ9</accession>
    <name>A0ABR1VWZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_009504</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665781.1">
        <property type="nucleotide sequence ID" value="XM_066813819.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046879"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038:SF16">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="13">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8074841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="98" mass="10449" checksum="1F6FC8C3FA70B461" modified="2025-10-08" version="1">MSFLGFGRPQPSSAEKIAAVEAEMKLMSDMLNRLNRACAKKCIPNDYREGDLNKGESVCLDRCAAKFFDVHLKVSEQMQNEAAARGGAGGGGSFGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXN4</accession>
    <name>A0ABR1VXN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009307</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665584.1">
        <property type="nucleotide sequence ID" value="XM_066813622.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046682"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14125">
        <property type="entry name" value="STKc_CK1_delta_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="12"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="310"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="324"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8074644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="393" mass="44342" checksum="69B20F014B84F80D" modified="2025-10-08" version="1">MTTMDLRVGNKYRIGRKIGSGSFGDIYLGTNIISGEEIAIKLESVKAKHPQLEYEARVYKSLAGGVGIPFVRWFGTECDYNAMVLDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEYIHAKSFIHRDIKPDNFLMGIGKRGNQVNVIDFGLAKKYRDPKTHFHIPYRENKNLTGTARYASINTHLGVEQSRRDDMESLGYVMLYFCRGSLPWQGLKAATKKQKYDRIMEKKMTTPTEVLCRGFPNEFAIYLNYTRSLRFDDKPDYSYLRKIFRDLFVREGFQYDYVFDWTVYKYQKNAQAIAQAAGQPAAGDEEEKARASRTNAATAGQPSSAVKPNAIPGSRRKVLERGAPGVDTPDTNRAVGGSDRMLRSASKGQGTGSGYGSYRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY56</accession>
    <name>A0ABR1VY56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009502</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665779.1">
        <property type="nucleotide sequence ID" value="XM_066813817.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046877"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053169">
        <property type="entry name" value="MUG_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791:SF2">
        <property type="entry name" value="ENDO MANNANASE, GH76 FAMILY (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047167929" evidence="2">
        <location>
            <begin position="27"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="659" mass="72252" checksum="8C90DC8C0EFB7B42" modified="2025-10-08" version="1">MAHAGLSNFWLALAVLPGLFGHSAIAADPLQGERCSIVSLPGYKSCDASALRDFVPATDVVADTTPGQGTKSRAGGGEPDLEVLGNVLEGIGVLQANYFKQWLGTWPGSIDWTGAVVGTHVSGTLSTLSEAFPLLNSSEGGGAEDWKRKVNLVEGYFAHMVAYYFGQNHFEIRNQAYDDILWVVLGWLETVQFVNKHTDLHYELNSQDSLWSGSQASDSIEETFSNQTWHGNGWISSFSHRSRVFWELALKGWDTEYCGGGMDWSPHKLLYKNAITNELWIAGSISMYLHFPGDGNPSPYQGKQSGPGAARFSPDHPRSGYRNPKFLQAAIDGYNWLVGSGMMDHRGLYTDGFHVSGKMDPENNNTKCDERDNMVYTYNQGVILTGQRGLWEATGAPSYLSDGHRLIQSVIKATGYDLKQGKPLEDPALTRPQVIPPWHGLGRAGILEDECDASANCSQDGQSFKGIYFHHLATFCEPLAAPITPEGVQVDMQAFKTAKEAHDEACASYGSWLKHNADAALGTRDDGKFGQWWTASLLKDYDGPWPTLETDGIDHAAAGIDYRNYGVPNDTTWRRPSDLVMIPEPPLPIGIPTTGTADGGQKLLNRAPDATESHSSTRMKREQQREDDPNNRGLGRTVETQGGGLAVVRAYWNIVHAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZ19</accession>
    <name>A0ABR1VZ19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009832</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666109.1">
        <property type="nucleotide sequence ID" value="XM_066814147.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047207"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF15">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="61"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="257" mass="27525" checksum="CCDB2EC6D96CBBE9" modified="2025-10-08" version="1">MAALLEPQSFSLSLLLSSVVSAFIATFFVGIRLFLSVTAEEVGLGRPVCCFGSAACGYGTFVGIGAQVETPTSGSKPKDLNESLGVTFFIAMILYSGVLVCIKSAVCILFLRIAGPIRSYRRCVFGILGITVVGFVVTEAGTMGECRPIEANWDTDVHQTADCASEDIIVIIASFSTVTTILTDWLCSLFPAYMLWRTSMPVRKKLAAGIVLSLGALASICTLLRIPYVMDYNAAIAENSKNREGKEDISLLFATRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8E5</accession>
    <name>A0ABR1W8E5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667231.1">
        <property type="nucleotide sequence ID" value="XM_066811889.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044949"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="2"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="334" mass="35502" checksum="58E3DD5ECF34291C" modified="2025-10-08" version="1">MSASKKTTIPSYQSPPKPDQLRIRIKAASLNPVDAQLMGNPLWPYLPAALVRAHKGVGEDFSGVVEEAGMSSGFQAGDEVFGIAPFLPEGTLQEVIQLDVSGSSSSASASAVVLPKPADWSWEQAAAVPLVWITAQTCIAKAAPWVPANGNGHGNGKIAILGGSSSCGIYAVYIAKQRGWEVAATCSSKNAEHVRSMGADTVIDYTTAVVSEQIKAFAPDAILDFVGGVECLGLARRYVTVCGEKTSRLAIGGRVVYLWNPQMVLRALLGRIGLGFSYTCINLEVKPPNLEGVLSLPKDKIFIDSTFGFDEAMEAFERLNSSRARGKVIVRVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8U3</accession>
    <name>A0ABR1W8U3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GPI inositol-deacylase</fullName>
            <ecNumber evidence="12">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_007719</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="12"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667376.1">
        <property type="nucleotide sequence ID" value="XM_066812034.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045094"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039529">
        <property type="entry name" value="PGAP1/BST1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495:SF7">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495">
        <property type="entry name" value="NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase PGAP1-like alpha/beta" evidence="14">
        <location>
            <begin position="206"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8079901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="39463" checksum="5F1099EC570B31FA" modified="2025-10-08" version="1">MQRRSSASSVSSADALIETTIQRSHGKEEVDKPIGLVNSPRKAAQSEPKSKEAHPSSRASAARIRRPSSNVNWKPAHSRNGSVAARDTATNPSFPATVSSQKDLVQDEHETSKMTDKKQLGRRAWSRNPWATTWLVFLTTLAGVAMLASILNSSVTRQLDPKGCRMSYMNPRYIHLSEFDTEHTRFASKYSLYLYREGGVYESPMVSGIPVLFVPGNAGSYKQVRPIAAEAARYFHDVLQHDPALAGSGVRNLDFFTVDFNEDFSAFHGQTMLDQAEYLNEVIRYILSLYLDPRTSGRRDPNSPDPTSVIILGHSMGGIVARTMLIMPNYQSKSINTIVTMSAPMRVRPSALTLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W960</accession>
    <name>A0ABR1W960_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tuberous sclerosis 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667057.1">
        <property type="nucleotide sequence ID" value="XM_066811715.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044775"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007483">
        <property type="entry name" value="Hamartin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154:SF2">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04388">
        <property type="entry name" value="Hamartin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="442"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="537"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="910"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="701"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="442"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="475"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="537"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="559"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="949" mass="107164" checksum="13630883873E157B" modified="2025-10-08" version="1">MASAPSFKELSKAISSFIPTARLPLPDDLIEIIEGYLEKHEKFDESVADKLNDDLIAIYQKDVKGTQARYGPFINILRRLRPLIGQPAKVIQWEKDLASEAHKLFRDILASDDVESADDPAAGAAIALAEKVMAFWVQDRCSAIRADAGLAVFKEKQLREVLIIYGKRHPMDFMGLLDKYMVDKKWRSHALNLMGDYIQSQPPHLHQILQTPIFGTLTNILQLDTSTTVVTMALTVLTMILPHMPSSLVPHLSTLFNVYARILFWERELSAIELGVSAYAERRISPSAAGWQKMAYMPEVEEKTIPQLLNYFTILYGLYPINFMDYIRKPQRYLRHADAPDSDEIEVQPTEIRHASEQFRQCHALHENFYTLTIDSEKTDFGRWIKSEPAEVVANCMALRYSIEMDGEPDLPFGQLGARNSSTRGDFEKDLQDHALLSTSLSRANSSFGGPSRDNSQPPFIESPISGRSYPTIIRQSSQSSRHSLHDGSSARPSGRGGDSPALQAQLTSFGSQTHLQDLINSNKAIKSELHQSLANDSVPSLALSQQESNYERPGPLTHGTTQYTSTPASATAVGDDQQYYHLYRQIMLLHNDLTFERFMKQQHLTHMGELRSRLLKQRLEEAKKIEVQTKKDSERSRTLAKKWEADLSSKLRVLREEQRKWNAERDSLTRDLEVIKVETDKLRVLVSEAETRELGWKQRVQSVEADASELEHLRKEVERLTVSERNYQAQENERQAAMSGAEEADRRAEMLEMKLKARGVEIQQAHDLYQSQIAVLNNKLQDALKNGVEKKADGLKVQVESLMTASRAQQEELKKRIADLTSKNAALNATILELQSQIPHRSSADLPRPASPDTNMPVRYSVDSGSPMSYRSRQHRGLSDLENYDADVYNATEPLEPYSSSLHIGSPIARSSTPSLAEGSDFTGRGSPTGERYYGRGASQRIMKLWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W981</accession>
    <name>A0ABR1W981_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007872</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667529.1">
        <property type="nucleotide sequence ID" value="XM_066812187.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045247"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11333">
        <property type="entry name" value="AmyAc_SI_OligoGlu_DGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF232">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 13 CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="4">
        <location>
            <begin position="56"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="50"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="634" mass="72771" checksum="669235A2D3783E6D" modified="2025-10-08" version="1">MMLQVDPCLGNRTSSGSENTKIYNSAGRTLTERLSKGTLSSFEVRHNAPCLPQANRFPRSQHPSGGKRLWSTRSTHRPSSPTQGPHRDGGSIKGIISRLDYLKSLGVNVVWSSPIFKSPQADMGYDIADYKDIDHRYGTLEDVDTLIAELKKRDMKLMMDLVVNHTSNENAWFLESRSSKDNPKRDWYIWRKPKSISADGKPEPPNNWAMILGEGNSAWTYDEKTGEYYLSLFTSEQPDLNWENPDRGAAGFRMDVINLISKVPGYPDADIVLSAGHKYQPAFKHFVNGPKLHDYLQEMHREVLSKYDTITVGEMPGVSEPKEILRTVGANAGELRMIFIFDLVDIDKPHVRMSLKPWDVKDMKAIVTKWQRVMSEQDGWNSVFIENHDNPRSITRYADDSDRYRHISARLLALMQTTLSGTLFVYQGEEIGMRNIDPERWDIAEYKDCETINYWDKCQEIYAGDAEMLRHCRAVVDMKARDHARTPMHWNAQENAGFCDAGVKPWMRVMDDYEAVNAEAQMDASDPENLSPWQFWQQALQDRQEHADAFVYGGFQELSPEHPNVYAYIKIGSKTGEKWLVVLNFSGREVEWHMPADHKIDFWARSNYIKNQINKPKEDLVPLRPWEGVLGKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9B5</accession>
    <name>A0ABR1W9B5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_007890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667547.1">
        <property type="nucleotide sequence ID" value="XM_066812205.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045265"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF107">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="543"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="578" mass="65806" checksum="8DD85537F5AB970A" modified="2025-10-08" version="1">MELLTSGQWQAWPLLQACIKAAFLLLGFNMGLFFFEGYQIRMKFRKMKEQGIPIAEPHSLVWGHLKMMVAIRAHFPKDAHNHYAQIYLVQNWQKFFPGAEERPPIMYFDLWPVLEPFAFVVNPAMCQDIVQDRLQPRHPQIKHLIKYISGARNLTGWDQPVHTLWRSRLNPGFSARNLQSHIPTFIEEVETFVDLLKAKAPKDGSWGEVFQLLNLTTNMTFDIICRVAMNVNTNEQRVGPTDLQNSMRTLVRNHVIFKNLGTLPLRLSPSWNLEAWRCSRTLRRALMPRIQEQIGSGEQATTQKTVIQLATKEISNESSAAGGNSKQTTPLDKKQYSEDVLNLMKQFLFAGHDTTSTTITWAFHFLAKHPAALDRLRIEHTTVFGPDPRAASAMLTANPALLNALPYTNAVIKEVLRLSPLAATIRRGSPSFFFTHHSAASGTTRHYPTDGFAVATGTAAMHHDPALWPRADEFIPERYLVPEGHELYPVKYAWRPFEYGPMNCIGQDLALMELRLVLLLTVRELDIETAWEEWDVLQGRVAGDEKPPTINGDRAYRTTNGLSYPTDDLPVHVRLRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA43</accession>
    <name>A0ABR1WA43_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667831.1">
        <property type="nucleotide sequence ID" value="XM_066812489.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045549"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="95" mass="9839" checksum="E425156E86408A79" modified="2025-10-08" version="1">MASTSSAMPTKDTTFDSDSSDGQARGGRRQLQQTGLPPLPTSSGLSAPAGQLLRGAVDDQGKNTKAALMVGIKLDLEAEVHLTARVRGDIAIGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAW6</accession>
    <name>A0ABR1WAW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Cysteine dioxygenase</fullName>
            <ecNumber evidence="2 7">1.13.11.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008453</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteine + O2 = 3-sulfino-L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20441"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:61085"/>
            <dbReference type="EC" id="1.13.11.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="7">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.20" evidence="2 7"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668110.1">
        <property type="nucleotide sequence ID" value="XM_066812768.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045828"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10548">
        <property type="entry name" value="cupin_CDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="CYSTEINE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918:SF1">
        <property type="entry name" value="CYSTEINE DIOXYGENASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="23580" checksum="7B098F3B7F5464BA" modified="2025-10-08" version="1">MTCTILSPLRQQETSGEAKMDRFDTLVESLKDILGPSSGITSDDVDVGDLMHAMEQYASDDREWSPYAMADASRAYTRNLVDEGNGKSNLLILVWSPGKASPIHDHGNAHCVMKILRGTLTETRYDFPDGDKNKPMQVKSTSHHKENAVAYMADELGVHRISNEGSDFAVSLHLYTPPNVAKSGCNIFDLRSGKKSHVPKCGYFSKFGRILKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAZ8</accession>
    <name>A0ABR1WAZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTPase Ypt2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008475</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668132.1">
        <property type="nucleotide sequence ID" value="XM_066812790.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045850"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01867">
        <property type="entry name" value="Rab8_Rab10_Rab13_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="203" mass="22477" checksum="A2ACBD7BB33C5C85" modified="2025-10-08" version="1">MSGNRNYDFLIKLLLIGDSGVGKSCCLLRFSEDSFTPSFITTIGIDFKIRTIELDGKRVKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDQRSFENIRTWFANVEQHATEGVNKILIGNKCDWEDKRVVSTEQGETLAKELGIPFLEVSAKSNINIDKAFYSLAADIKKRIIDTAKSEPAASSVNVAQGEGSGGLGKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB21</accession>
    <name>A0ABR1WB21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008518</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668175.1">
        <property type="nucleotide sequence ID" value="XM_066812833.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045893"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="4"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="831" mass="91842" checksum="E922FB70765E49AB" modified="2025-10-08" version="1">MVKSNVRNMSVIAHVDHGKSTLTDSLLAKCGIISSAKAGDARATDTRQDEQDRGITIKSTAISLYGELPSEEDIKDIQNQKTEGNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTVEGVCVQTETVLRQALAERIKPVVIINKVDRALLELQVSKEDLYQSFSRTIESVNVVISTYLDKSLGDLQVYPYKGTVAFGSGLHGWAFTVRQFATRYAKKFGVDRNKMMERLWGDNYFNPHTKKWTTKSSHEGKELERAFNQFILDPIFKIFSAVMNFKKDEVTTLLAKLDLKLETADKDKEGKQLLKAVMKTFLPAADSLMEMMILHLPSPVTAQKYRVETLYEGPQDDEAAIAIRDCDPKGPLMLYVSKMVPTSDKGRFYAFGRVFAGTVRSGLKVRIQGPNYIPGKKEDLFIKAIQRTVLMMGGKVDPIDDMPAGNIVGLVGIDQFLLKSGTLTTSETAHNMKVMKFSVSPVVQRSVQVKNAQDLPKLVEGLKRLSKSDPCVLTSSNESGEHVVAGAGELHLEICLNDLENDHAGVPLIISDPVVGYRESIAGKSSMTALSKSPNKHNRIYMTAEPIDEELALAIEAGKISPREDFKTRARTLADDFGWDVTDARKIWCFGPDTQGPNLLVDQTKAVQYLNEIKDSVVSGFQWATREGPVAEEPMRGVRWNIMDVTLHADAIHRGAGQIMPTTRRVLYASTLLSEPALQEPVFLVEIQVPEQAMGGVYGVLTRRRGHVFAEEQRPGTPLFTIKAYLPVMESFGFNADLRQGTGGQAFPQMVFDHWQVLPGGSPLDNTSKVGGIVNTIRKRKGLKVDVPDVSNYYDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCH9</accession>
    <name>A0ABR1WCH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668681.1">
        <property type="nucleotide sequence ID" value="XM_066813339.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046399"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="140" mass="15282" checksum="C27C5C7B8452AB45" modified="2025-10-08" version="1">MRTDSRDPRQQQEEEERSRPPLKLRPEESILYISSASGPPPPAASSSPPDPGPGSSRFALSSWIEEAGAGSRSSSRRSHYHHNHHSSSRSHAGSTTELADWSGGITKTTEVSQSSQHRLDSLPRMDAVLLLTKRAPDEMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEW8</accession>
    <name>A0ABR1WEW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mucoidy inhibitor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008869</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668526.1">
        <property type="nucleotide sequence ID" value="XM_066813184.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046244"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011935">
        <property type="entry name" value="CHP02231"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037291">
        <property type="entry name" value="DUF4139"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025554">
        <property type="entry name" value="DUF4140"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005:SF8">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13598">
        <property type="entry name" value="DUF4139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13600">
        <property type="entry name" value="DUF4140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4140" evidence="3">
        <location>
            <begin position="19"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4139" evidence="2">
        <location>
            <begin position="316"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8081051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="556" mass="62164" checksum="0EEFE326248686C8" modified="2025-10-08" version="1">MDMTHKQEYRIRELETRSVTLFPGRAQVHRQIKDVPLKAGENQITIVGLTPTVDQDSIKVEGTGSAIITDMAVELLPNREIFEDVYPEYDNDGDSSDSDPDSASDGEGEEERANAVMGDIRERLRLAEDDEKRASEILAGARRRLEILDSYGKLMTTDRQNTAAPDVKIDEGLATYRAEREKIFADIWDGNVQHREIKDKLQRLRKEEGRIAKQYRRETAKADKVKRKEARAKQKEQQKAARKQQEVRKEQARVRKERESFWPKKVYSIRVTLDATAFTPGSSRRNSIASDVEVVSSPKSPEKSSDHEFSGSTCDLSISYVTTDAYWSPAYDMALSTTANTGHVCFDAQLTNQTAETWSNCKITLSTPQADFSGLHDTIPTLVPWRVRLTGGRAAHGDAYSLRNDIMFSRDEQSHRAAWADKQTGRTHAQQPRAELFGVVKSRAKSSRGAVVEPLMVGADEAKEEECEESDEEMGFGLFDGDDEPPRRSVNDGMTQHSLGGGAPPPFPRGGPPPPPPPPGGSFRPTMESASRGCFERFPSSQGEEEREHLASRQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFL8</accession>
    <name>A0ABR1WFL8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668434.1">
        <property type="nucleotide sequence ID" value="XM_066813092.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046152"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="244" mass="27583" checksum="1A520551C902DC66" modified="2025-10-08" version="1">MASNNDHDALAPPALRAARLPVIQDKLAVRFNSKKLHQYDWIFNNEEFKAAVMTVLGSNYLQVLEVFTNGSGIECRFLLLLANSMQVHQRGVKKRPYHDESEDDESAIGRTVLNGICCARLATEQTWQCMNMSEEKTKQVEEIVAHLKTHLVFPVSKYAKAAPYPIDTLRPCLYHLKVKRDRPFRLLSTWARSRSFSFVQTPSQAGILVRGKKHFRLLDCSLGITCDTCKCGAANAFKFGALYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLZ4</accession>
    <name>A0ABR1WLZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uroporphyrinogen-III synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669033.1">
        <property type="nucleotide sequence ID" value="XM_066810110.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043170"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390">
        <property type="entry name" value="UROPORPHYRINOGEN III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390:SF0">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="HemD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrapyrrole biosynthesis uroporphyrinogen III synthase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="302" mass="33817" checksum="D864539954719CFD" modified="2025-10-08" version="1">MAGTEQRTPVLLLKTKSGPTDAYQELFSTPRDGFDFEPTFVPVLQHQFEEDGLKVVRELLQNRKINKSHDASFGGLIFTSQRAVEAFGKLVGEGQGDESWPHLQDVPFYSVGPATTRALKAIHQSPPLQIFGEHTGNGDALAHFILEHYGEWYSDRPTKPPLLFLVGEQRRDIIPKTLMDPALAADKRIDVTETVVYGTGVMESFPKDFKEVLRQTSDRTRRWVVVFSPTGCDSMLRGLDMLGERGQVGDLPQQRSTFIATIGPTTRDYLKRTFGYEPDVCAEKPSPEGIWEGITKFNAQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMT2</accession>
    <name>A0ABR1WMT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669360.1">
        <property type="nucleotide sequence ID" value="XM_066810437.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043497"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="349" mass="37112" checksum="10BB85B47D7DAA72" modified="2025-10-08" version="1">MPSFTGRATEHAAAGRLEPVQQGRRVRPGICYEGHEFKAVTKVWTRNADLPGGGAPTSFVWKGVCCRSFHLEISEFDYATIMLLTQGTSTDLCTQTLTLTTPTGFPLLLSDAATDTAGQTTIRTSTALEARYQPFTMWWNDGDLSQFSSDDSDQLRVVMKEAASSFRLTGGGAGAPTTTRSISALFPDPTGAPKIGVEAQQKTSNGLSSGASAGIIVGAVLVLILAVLVGLMLGQRRHRRSSNAEHLDRPELSASADSKGHGWGGQQGAASARRTWLGRILGKRKSQASPSYYPAGHPSEGISAPEVVTGDHQSHYQIRSELAGLPRSELCGDSSPAAPRAHQRPSELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPG8</accession>
    <name>A0ABR1WPG8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006584</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669822.1">
        <property type="nucleotide sequence ID" value="XM_066810899.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043959"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961:SF2">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="286" mass="30854" checksum="2517B2443D22EBE6" modified="2025-10-08" version="1">MSSKFGASRLFHTLRALQHENPLGLPRTGTIPRMQRGLPERRPIKDVKKVVAVSSAKGGVGKSTVAGHRTGILDTDIFGPSIPTLFNLSEEPRLSSNNQLIPLSNYGVKTMSMGYLVGEDAPVVWRGLMVMKALQQLLHEVEWGGLDVLVLDLPPGTGDTQLSVTQQIVLDGSVIVTTPHTLAVKDAVKGINMFKKVNVPILGMVQNMSLFNCPHCHHDTAVFGSNERVHKVCSEHNIDVLGDIPLHQSIGDDGDRGKPTVVAEPDSARAAAFMQIAKKISAQIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPW1</accession>
    <name>A0ABR1WPW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670021.1">
        <property type="nucleotide sequence ID" value="XM_066811098.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044158"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="607" mass="68562" checksum="1F7A72239375D67C" modified="2025-10-08" version="1">MARKRYNCFSFPQERHLALLTRCGICRDEIGHNEKVVVSIRLPVLSNAACTSFEHLLGPFRFPDPDEPSKGPRRAVDGFFACIDASCHCWENSRDCCKLYLRHCQAADKLSRLWTAACWRNVWSKNTPIPWIESLPPRTTPAAAGLVGSALDVQRVEQWMALPPELLLRIHFLSRGAPLWRCIAAMELADIVDRSKPEALTEVPLSQITTWQREGGAEQTSEAAGPVFRIRIDDVGISHIDRVLHEPHFAGHTKQKNIAWIILTSKEAERVSVQFKDHIARLKLSGDFATPRICDTPEPINLDCIHTWTKLRGDMIYGPLVMRYSDDSDDPEAGDEWEAGDKVLNEGTCISLICDTSVPTNVLKSLGAYCQNPRWGDVRNQTSKHASFKRNKDKRYESADLTPFRAAQPRRIQITVTYSPQAAMMLQTYYASVTLDKHCCSAEVFEWGGEEGARYQHPQFAGAIFRFEDGSAQAVGQCRVGLDPSVTYRDPAHILWKLDAEANARRLSWGIPPDPADIDPAPLGPGVQKHLRRLRFEPAAWKPEEDPAGPAWDNKSGLWNAKPLGKRLDFWWSDEEVSFSMDGIHKMGPLEWHPRGEMPDWPEDIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQL0</accession>
    <name>A0ABR1WQL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670276.1">
        <property type="nucleotide sequence ID" value="XM_066811353.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044413"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="33217" checksum="F595D55C952FC8E0" modified="2025-10-08" version="1">MSPLEDLPAELRSLLLWNIPDLSSLRSLVHASPVFHAQYRADRDGILRACMGRDMDGFFIDAWATTRTRVSVMGSPRTFQQVTQFFSSYYSAAPINVDSMSSGCLCWLSAFHINVARPFAKLYTNWALANLKIAALSSPKKQQDAGTAAAEIDNGKTSSLSRSEEVRVLKAIYQYQTHHNLFGRNEARYDQTYVKHDLAVRFYNKFEPWEVEAIGCINVFLQDAYEVVFDEVKGELITLRQHFAIMAPTSFGPCDPDGPSPFAFMSTSSPFFIMTLLLRQRACMAFQIKEKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WR47</accession>
    <name>A0ABR1WR47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669400.1">
        <property type="nucleotide sequence ID" value="XM_066810477.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043537"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="37203" checksum="17E6BB3868C65849" modified="2025-10-08" version="1">MSELPLKVRVGIRDSWSSEDAPLREILGLDVAVEPEWPLLLAALDDSYPDKQTLVPAVAQCVRVWCDLLAAALEDEDANAEWTETLLERAGGLLRLFLEVQVSKNEGLRLTWSNDRTGFVITLPRGQMPYLTELEAALRGQLLNCFNKDAGASQSTTLASRAAAPADDWADVSLDAATGKAAVVESAKGADRYSNTQYAPPTKSAYTVMPDCGTLARPDDLLLKPPYHLVGSSEVEIHSSHSPSLQLLSEYLKKWCRVNQQNHQKPPCVDIKLHQSAFGLGLIYDRLTLSVDRPYAQYGVSPMIVLSLVEGVLGYQNVGNEGSCWKFRKDVELKRYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRU1</accession>
    <name>A0ABR1WRU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670015.1">
        <property type="nucleotide sequence ID" value="XM_066811092.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044152"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="63" mass="7269" checksum="F78B14DFF24F6CEF" modified="2025-10-08" version="1">MEDLLCCGEMVAKGYMLETSDVVERLTGRRPLRFKEVLMKYKSTFPLAEDTSDCDHVANHCRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRX0</accession>
    <name>A0ABR1WRX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669682.1">
        <property type="nucleotide sequence ID" value="XM_066810759.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043819"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="294" mass="32491" checksum="DA5CBA2126ADD630" modified="2025-10-08" version="1">MPMNKLSTPEPVIALNVKEAEIEHTFFVHADLLTTSTYFKDMFIANPGLTEHTLPPGPDVKTVGNYVSILYTHTHTHVRPLGLSASDGRTTLSQIISLARVYRLTSKLCLDHSWVMNSAYNAAKDLLQNVELAWGPGEAGQTISQLQSAFVEWSGDYGRWTTSRNIVRMIVETFASTCPEIVFEMHTELLDRKLLDAIALRLMRLTRKLETEIIHKISTTPGAAVHKGAPEPSIATAAAGPSTLQPTTNTNVFPPIAASPELPARQRRRHARSVSASCAGDENRHNRYDPAPFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWX9</accession>
    <name>A0ABR1WWX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">O-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002606</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670539.1">
        <property type="nucleotide sequence ID" value="XM_066806921.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039981"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF12">
        <property type="entry name" value="STERIGMATOCYSTIN 8-O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="5">
        <location>
            <begin position="94"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="165"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8087645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="44238" checksum="535B3661CD7C5533" modified="2025-10-08" version="1">MDVCRIAQLAHTINVSVAQIRESLEKQGLPLPSHDENAPSLPSSIAEARTAAIDASTELHYLLTEPIDTIHQVCKRHTRRLYNKLIIRQADKKACVQSIIRFDIAAAIPLGGQISFTDIAANTPLTEQMVGRLIRHAATMHIFHEPEVGFVAHTRASRLLVRSDGYSLAHGTSGSIYDVISEDPERALRFSNAMKVMASRPEFDLTYATETYDWESLDEALVVEVGGAQGHFALALASRYPSLSIMVQDMEKVIDKASAGALKERVRFMTHDLFDPQRVQADVFFFRWIFHNWSDKYCIHIIRAQIPALRRGSRLLIQEALMPEPGSVCPDAERTARSLDIEMAYTFNARERTLSEWKALFREASPSFIFNNAIEPKGSALAILEFAWEGIEQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX12</accession>
    <name>A0ABR1WX12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002665</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670598.1">
        <property type="nucleotide sequence ID" value="XM_066806980.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040040"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF193">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G00940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="57"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8087704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="568" mass="61140" checksum="50DFBABAA562BBB2" modified="2025-10-08" version="1" fragment="single">MISPEATAGESGKAAAPTMAIEQQQQQNKVASPPEARNEFQPKYVTGIRLALHHEYFFLSTSHGSWLFQLTYGLPSQAIPRITDEFRSLPDVGWYAGVYRFGIAAPQPLIGKVYTHFKTKWTFLFFFLLFELGSVLCGAAINSTMLIVGRVIAGLGAAGIINGAITIVSSCAPLEKRPALLGLVMGIQQLGLVVGPLIGGAFTTYSTWRWSFYINLPIGSITVILTIILRIPEQTPKKSPLSVLPQLHHHLDLVGFTPFAPAVIQLLLALQYGGNQYAWNSSQVIGLFCGFGATAIVWFIWNHHKGDRALLPAAMIRRRTVWSAAMFNAFQMVGIYGLFYYLPIYFQSVYNASAIMSGVYVIPFIVPQLLAAGMSGGILQKTGYVIPVAVFSLVLSSVGAGLMSTLQADSSVGRWVGFQILAGVGSGAALQLGLISMQSATSGEELSSGMAFMVFTQSLFPAIVLPLCNVVLVSSLKAQLPIYAPGINVAAVIEAGATSFRKVVDAKDLGGVIAAYAQSVDRVFYLNTGMVVASGLFIWGIGWYDIRKKDGTGVSADREHSGTDDKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY33</accession>
    <name>A0ABR1WY33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670945.1">
        <property type="nucleotide sequence ID" value="XM_066807327.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040387"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="520"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="629" mass="68739" checksum="79920DA54E411AD2" modified="2025-10-08" version="1">MPRPKRTRVASTRSAAPIAQKEPSPALLPVVQPASSSSTDIYDVSDREKPGRRSTRSTAARTSAAAATTTNPRQAAAINASKKNRDSAMQRLENITSTVTGTTNTTENEAEDSSDSADIEVGRRADATPPRAAAGGRRADFSGLDLDDSMFDDLNTTINTAGPASAQRSLDMSTLTASNYKRRPRGNSFLSRNDGPIRPSSRAGPNTPAFSSTFDINNFRRRPREPSILGTAQKERPRRPEPESDSGEKPDDEDDLESEEEGEEEQVPAEDFAPEAESTPPPRRSSRRSAVAVEARESSLELSLSVNPRKRKSTELHEHRPRSSPFADNPLAAEESENETASQPGSLPPMDVRPSTPVMEEEDVPPPLSSSSEEEAEIWPPLKSLAKGRTRRAPSVQRITPVRDIGGDNLSDMSSPPSLTYSPNYDEPSPPPPQRTVKTRKAAKAEAKLTTADLTGLLPRRRHRSNRADPFAVNDTEEEEVDATGLGNDDDELYHLDGRSTRRRPARPLARSGNKNQNETAAAGKTTAAAQRKGKQPAQPAANKRSTRRRTYGKNSDKENEGDQDENDNENGNENRDPFREGETTENSDELVARVGVELKNASRKFAEVDKWELAYETMTQSSSPSNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYN3</accession>
    <name>A0ABR1WYN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003207</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671140.1">
        <property type="nucleotide sequence ID" value="XM_066807522.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040582"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="112"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="472" mass="49828" checksum="9C7A555567BB6C6F" modified="2025-10-08" version="1">MSYQYPPPPQDGADMDLPHAGYISSYATPSASSMEVRNRTAHPPQPPDPAQDTLMPLVQRRDSVQKSYKLRRAFSTPNVRKQGANDPDNGHMALSSSEKRRNKLGYHRTSVACGHCRRRKIRCILQPADPGGRCMNCIRLKKECSFFPVDQQPPALPGQKQGTRSSVGSKITSTSSSPAMTTGQPPDAARHPMYPQLSTSQSLQHMGPPAMQSASANTYSVAPEASGLVLSHPLHQTKVFDVETIEGACVHMLNTPGTRAYEFGHGVSEWMATDASGSSSTKSIEDLNASWRSYPQASPVSPAFSPYTTHAVPGSATWSAVPGAVGEEAGSRAEDVPWSSYAAATTRSMPYGSSGAESHGTYSPMTGSRTFDSRRLSTTAAYAPAISAAALSGGVAAVDSAVDQHASSLSAGAGAPPNYGAWSPHSYGGAYGRRTDGYGSVWYSEGTAGAQEAPGGGESMHHHAGALYYGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ10</accession>
    <name>A0ABR1WZ10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">BZIP transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_003327</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Positive regulator of amino acid starvation-induced autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus</location>
            <location evidence="4">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SCOC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671260.1">
        <property type="nucleotide sequence ID" value="XM_066807642.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040702"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019357">
        <property type="entry name" value="SCOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21614:SF0">
        <property type="entry name" value="GEO08385P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21614">
        <property type="entry name" value="SHORT COILED COIL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10224">
        <property type="entry name" value="DUF2205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8088366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="16604" checksum="790DFD2B36A113A3" modified="2025-10-08" version="1">MSESFPAVEPPRPQRADSSSGSSVESQEIHMPIPTRPRLPSRKSSGTLIVPRDSSQVGPVPTVFGSDDVRAMSPRRNSEDLDKMGREAREELHRHAKALQDSLLLLFNRIEAVKEEHDKLDNNNKFLQKYIGDLMSTSKITAGGIRGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ58</accession>
    <name>A0ABR1WZ58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003389</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671322.1">
        <property type="nucleotide sequence ID" value="XM_066807704.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040764"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="112"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="177" mass="20109" checksum="03175F38373F6888" modified="2025-10-08" version="1">MRPDWSFPFVNPSWVQSGNEGPLPEWSWDDLATADEPAGQDGQVEEATPPRANEDDDNTSNPQIPPQNNSNDPHDPPEPAVPGNRFQCPECPRYFRYKKQLTTHLRTHTRPFHCQVADCGARFALKKDLERHAKEVHSPTRWYCTVQGCKYKLAVEGTARKANLDRHMRTQHGVAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ90</accession>
    <name>A0ABR1WZ90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carbohydrate-binding module family 19 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671344.1">
        <property type="nucleotide sequence ID" value="XM_066807726.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040786"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="27634" checksum="57DDDE9BF31E4185" modified="2025-10-08" version="1">MASNLAEAKKYNDLFGGLKEDSACMAGQVACVNDNIGQCGNSGAFSITPCMGNTKCFALPMNTTAGVQVGCYDPNVAGRILGDSKQAPSESATATATTSKANSGQPSEVTVTVVPTEVVTSIIMAPPKETPGTTTVTEAPSTTLVTMTRSSTSPSPASLTTIVVVPPVVIPPVVSSSSAPPPPPPAPVPSTTSESKPSQQPPSTLTSLEIIPITRPHHGPKNPIPTNFPLHSTAKAIANPAAGGPVTVTVKETETVTTTTTTTDLATVTATASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZK7</accession>
    <name>A0ABR1WZK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Adenylyl-sulfate kinase</fullName>
            <ecNumber evidence="4 11">2.7.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_003547</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the synthesis of activated sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the APS kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.25" evidence="4 11"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671480.1">
        <property type="nucleotide sequence ID" value="XM_066807862.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040922"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00065">
        <property type="entry name" value="Adenylyl_sulf_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059117">
        <property type="entry name" value="APS_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003013">
        <property type="entry name" value="PRK03846.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11055">
        <property type="entry name" value="BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11055:SF1">
        <property type="entry name" value="PAPS SYNTHETASE, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01583">
        <property type="entry name" value="APS_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="8 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APS kinase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8088586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="210" mass="23311" checksum="6D0F339F244E54BF" modified="2025-10-08" version="1">MASNITWHPSLSRKERNEFRGQKGMTIWFTGLSASGKSTVATALEQHLLHLGLASYRLDGDNVRFGLNKDLGFSEKDRNENIRRIAEVAKLFADSSTIALTSFISPYKADRQTARELHAASAAGSTDEPIPFIEVYVDVPIDVAEQRDPKGLYKKARAGEIKDFTGISAPYEAPDHPEIVIKTHESSVEECVAQIVEWLQAKGLIELKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZU3</accession>
    <name>A0ABR1WZU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ADP-ribosylation factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003583</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671516.1">
        <property type="nucleotide sequence ID" value="XM_066807898.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040958"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="109"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="28787" checksum="2E8C91504EF1EF9A" modified="2025-10-08" version="1">MYHLAKGLYRLATSKEEYSVILLGLDNAGKTTFHEQAKSLFLPEHPDPKLRTVPTVGQNVSTLTLPDMYLKIWDVGGQLSLRRLWQSYYASCHAIVFIIDSTDIGDGLLLPGEDDDDDDGDGGGRGSKDNDDADSVATTAGTRSERRSSSSRGHGHSSSGSKHLGRLDECRLVLEDVLQHSETEGVPLLILANKQDREDCVEVVKIKEGLVKKVFEGDKASSIRDSRVLPVSALTGTGVSEAVDWVRSRVKWNKESRPPVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0H2</accession>
    <name>A0ABR1X0H2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I glutamine amidotransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671785.1">
        <property type="nucleotide sequence ID" value="XM_066808167.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041227"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF7">
        <property type="entry name" value="DJ-1_PFPI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="251" mass="26963" checksum="294646C0F5115420" modified="2025-10-08" version="1">MGKQNVVRIGVFIPTECQLLDVACIDIFGTMSHEYMSLVAGLVPQAVIDLAPSGVPGLLGPYRLCQPSDPPYVGHEHPAHASLLEAAVRAGKFEIVLVPGPDPSTVLDAGAAEWLRRQGEVETTDILSICTGILICGEAGLLKGRTACGPRGLQEKIRDRFGPDIVLKGTELRWVQDGRLWSSGGVTNGNDLVAAYARQSQHFPGPVVEVALAMTDTGDRAQKYSQGQTSFVLGMVWNILGAAFLGFWRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0K0</accession>
    <name>A0ABR1X0K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003920</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Endoplasmic reticulum membrane</location>
            <topology evidence="2 10">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the OST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671853.1">
        <property type="nucleotide sequence ID" value="XM_066808235.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041295"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007676">
        <property type="entry name" value="Ribophorin_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049">
        <property type="entry name" value="RIBOPHORIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04597">
        <property type="entry name" value="Ribophorin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044968472" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1" evidence="10">
        <location>
            <begin position="22"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="468"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="494" mass="55408" checksum="30F9D3E7DDDC6E98" modified="2025-10-08" version="1">MKSIAACAATLLSLISPIVTADTNVAVPSVSKVTLPATFKPPQVFKNANLVHVISLEKNFAKEQINVVVENDSKEPQDEYFLPFTSQQMERVGGFEVKDRKDSSLTGFVVEAVEYDPLSDTQYYRIRLPAPLPPKAQQTIGISFHYLQALTPLPAAIEQTDKQYLVYSFSAYCPSIYTTVKQKTEVKLPGSDIPEYTKIAGSGDVKEFPQKSGAKLTYGPFPEVPAGAVSPVKVRYEFTKPVSHVTLLERDVEVSHWGGNIAFEERYTLYNQGANLSTLFNRVKWAQSQYFNPTSYALKEMKFPLRIGSTDAYFTDAIGNVSTSRFRSNKKEASLEIKPRYPIFGGWKYPFTIGWNADAKYFLRQKTGDSYILNIPFLEGPKQPEGFGYEQVQVRVLLPEGADNVKFHTSIPKSSITDVVVDQQKTYLDTIGRTVLTIKARNLHDDFRDRDLIISYDYTIAASLRKPLVVFGSMLSLFVGIWLLSKVDVKLSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1G5</accession>
    <name>A0ABR1X1G5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SUR7 family protein pun1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672132.1">
        <property type="nucleotide sequence ID" value="XM_066808514.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041574"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052413">
        <property type="entry name" value="SUR7_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019">
        <property type="entry name" value="CELL MEMBRANE PROTEIN YLR413W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019:SF2">
        <property type="entry name" value="CELL MEMBRANE PROTEIN YLR413W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="34599" checksum="679116B9EBB4AD0B" modified="2025-10-08" version="1">MALPGFRKRRSANAANADGSAKGGASANNDAIIKQLTKTRRNAALVSSFCYLLAFVFLVLVEIGNTKGTKVLGDIYFFKLDLANIIPQSVPSLSLMNSIARTLGLHDFYQVGLWNFCEGYDDEGITYCSTPTNLWWFNPVEILKNELFAGASIPLPNQVNEILNYLHLASNIMFGFFLASTILDFLMIFIAPVVLYSRWWSMPVGIMSFINFILALVAAAIGTAMSLIFKYALTSQSDLNIQVETGTKMLAFSWIAVGFTFLSFIIHSGLCCCCTSRRDVRTGRKGSQSMPAGSMEEKSKTGSKLPSFGRDSTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1M3</accession>
    <name>A0ABR1X1M3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enolase-phosphatase E1</fullName>
            <ecNumber evidence="6">3.1.3.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">2,3-diketo-5-methylthio-1-phosphopentane phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UTR4</name>
        <name evidence="8" type="ORF">PG997_004279</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="3.1.3.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.77" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672212.1">
        <property type="nucleotide sequence ID" value="XM_066808594.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041654"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01629">
        <property type="entry name" value="HAD_EP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03117">
        <property type="entry name" value="Salvage_MtnC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023943">
        <property type="entry name" value="Enolase-ppase_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027511">
        <property type="entry name" value="ENOPH1_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01691">
        <property type="entry name" value="enolase-ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20371">
        <property type="entry name" value="ENOLASE-PHOSPHATASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20371:SF1">
        <property type="entry name" value="ENOLASE-PHOSPHATASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01133">
        <property type="entry name" value="C1.5.4:_Enolase-phosphatase_Li"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="246"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="274"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="127"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="340" mass="37424" checksum="F1ECA090C2BAA77C" modified="2025-10-08" version="1">MAASTAVQVVLLDIEGTVCPISFVKDVLFPHALKALPETVKEQWDKPEFKVYRDEFPAEFSGSQDAFQAHVVDLVARDVKVSYLKTLQGYLWEEGYRSGQIKAPLFSDVAPMLARWHGQGIKLMIYSSGSVAAQKLLFKYTNAEPSDLTMLISDWFDTVNAGLKTESGSYEKIASNYPDVLPSQFLFLSDNVAEVDAAIAAGMQSKVIFRPGNAELASDVRERLQVLESFDELEADLNTKKLEALGKRDRSETEEVEREAVDEKEAAAAPSNSDKTKEEAVAAEDSHKDKKLKPLDNDKAEERRPSGTNRTEDELPAAPSAGTGTTISDLLNEVEQSNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X210</accession>
    <name>A0ABR1X210_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial outer membrane protein porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic mitochondrial porin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672308.1">
        <property type="nucleotide sequence ID" value="XM_066808690.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041750"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07306">
        <property type="entry name" value="Porin3_VDAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001925">
        <property type="entry name" value="Porin_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743:SF70">
        <property type="entry name" value="GH26960P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00185">
        <property type="entry name" value="EUKARYTPORIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00558">
        <property type="entry name" value="EUKARYOTIC_PORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="283" mass="29786" checksum="1E16A783CD63DE59" modified="2025-10-08" version="1">MSVPAFSDIAKSANDLLNKDFYHLSSGTVEIKSNTPNNVAFKVTGKSSHEKATSGNMEAKWADKARGLTLTQTWNTANALESKVEAADVLAKGVKAELVHGFLPTTSSRSAKLNLHFKQSAFHGRAFFDLLKGPTANIDAVVGHDGFLAGASAGYDVQKAALTGYSAAVGYAAPSYSAAITATDNLSVFAASYYHKVNGQVEAGAKATWNSKSGNNVGLEVASKYRLDPLSFAKAKINDRGVAAISYNTLLRPGVNLGLGGSFDTQKLDQATHKVGVSFTFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X217</accession>
    <name>A0ABR1X217_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mcm2 3 5 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672342.1">
        <property type="nucleotide sequence ID" value="XM_066808724.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041784"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="798"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="922" mass="101854" checksum="A627B77271A66106" modified="2025-10-08" version="1">MADSSRAHDEGQRSSLLPSAFSRGHAYERMNADGDIDLADVAPTRPYSPIETRDLHATPPLDVPSYLQPPRRPSAISPVGTGDVGAPMSARVDPSSYSTPSFIITHQDEPPVQAESTATSSRPQSERQTRFTEMLKTSLTSPGDRSIDPLSDPAGNPYLGASSVRSSLLVPDDDRKDRQRDYETDSLSKRYGNDPHSQAPLDCHSKQDVHVRRRSWFYGQLVFFSILSTLLSCLWFSVAIGKPKYGYSISSSGTGKSLMKPATASLLAAVGAKLTELTFVTVFVGCVGQVLTRRAFAENSKGMTISEMNLRNWAIQPGTLVSHYETIPYAWKTLLGFLTLLATVASMLYTTASDAMVAPKLRLGPWEDQTLEGLVKTSYANPEYIKSTCTTPISEDLDELNAGVSCVEVEYSGQSYRNLLSFMKSWQTLGNNITSESPGMDMRSRPVGTAILYDNTTLTSAWVDTKYSDPKKAFDDHKRIVNNVTLAMPHPGVYAAATDPRNKILQPSELSGVGEYLIEASVVSPVVNTLCVNLSPRELEPLVYTAWPDAKRKDSEIPGQSMADPAWLNDIPLADDKTWLNRTAVDDIFRWGPKYGRRPPIFPMFPLEYNMITNTSVYMSDSIYLVAKAPGKVVGDFTICELRSWLTPQCATHFNISGVTGARMVAHCDGEQDTYKDMYGVPSGPISPNMSTDWRNVADQWRLSMDINGGVQNNNASNARIFTNLILREPALSTTLPSMAEAISVLASSTLIVGSKQSTFQHFWDHPNATLEPGVYETFSVMVKTQQYASEYEKDWQFCFYFVLGAVFLLNCLCLLYLLFTANGMVTDVTEPQNAFALAINSPPSRQLYGSCGSGPKDRELEVPWRLAYASSANHYYFEEANQSPWRGRFSGQTLDNSSVRSLADGSYSKSYKRLSTGRSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X348</accession>
    <name>A0ABR1X348_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation factor 1-beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004804</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the EF-1-beta/EF-1-delta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672737.1">
        <property type="nucleotide sequence ID" value="XM_066809119.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042179"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00292">
        <property type="entry name" value="EF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10308">
        <property type="entry name" value="GST_C_eEF1b_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036219">
        <property type="entry name" value="eEF-1beta-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018940">
        <property type="entry name" value="EF-1_beta_acid_region_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049720">
        <property type="entry name" value="EF1B_bsu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014038">
        <property type="entry name" value="EF1B_bsu/dsu_GNE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001326">
        <property type="entry name" value="Transl_elong_EF1B_B/D_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595">
        <property type="entry name" value="EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595:SF21">
        <property type="entry name" value="ELONGATION FACTOR 1-BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10587">
        <property type="entry name" value="EF-1_beta_acid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00736">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01182">
        <property type="entry name" value="EF-1_beta_acid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00888">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54984">
        <property type="entry name" value="eEF-1beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00824">
        <property type="entry name" value="EF1BD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00825">
        <property type="entry name" value="EF1BD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Elongation factor 1 beta central acidic region eukaryote" evidence="7">
        <location>
            <begin position="109"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange" evidence="6">
        <location>
            <begin position="146"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="76"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="25553" checksum="BACF7BD48DA67F31" modified="2025-10-08" version="1">MGFLDLLTDAGLATLNSWVQTRSYIVGHTPSQADVATFKALSAAPDAAKYPNAARWYKHIATFEDEFATLSGDASKPYTAYGPEESDLTVNPAKAPEKAEEDDDDDVDLFGSDDEEEEDPETVRVREERLAAYREKKAAKPKVAAKSIVTLDVKPWDDETDMAALEAAVRGIEKDGLVWGGSKLVPVGFGIKKLQINMVIEDEKVSTTELEEEIQEFEDYVQSTDIAAMQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3Q9</accession>
    <name>A0ABR1X3Q9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672945.1">
        <property type="nucleotide sequence ID" value="XM_066809327.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042387"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="635" mass="72245" checksum="AEEFDA99686CB5DA" modified="2025-10-08" version="1">MQFELLSPPQQHAVPYLEAEAPPHIPEGETIEWLLGEVDNSSKSAAKTKTYQELTDEERERTGLVRLSKRTDVIQGDPYGVLSSWTGNVSHQLDSDMTEVLKPIFEDLVSAARLRSAEISRLAAFLSQVPNTDPVTLAEKVADDGDYEVIEDTAESLELCFSLDSKRTRILWAKDLDVDNEKSYDDARRAKSSASRTKQVLTEPVMSITEQQILMARLYLEKRREFPGLVPDRGQKDSEQSDSTSSFEGFSGRGILATLRSVSQEHFWLRLNVEQRQYIRDLAELRQDHPELESVLSVIRANWKPTWNNGRYDTDYFRSYLVDSSASESVWKLVEDDLFIVLDQNRRPVFVNREGLVQSLYGNDVFDKLIRAIDLMTFYRPIPRPETKRHALDRHLLTHRHPELDPGRATIHTLPNAKMGVAHYGCWALKGDWHGRDIYQTKDTRAGRCFDNERCAQLIPRFMRAIFGTASDLVRFLLQPLDPVHYQECRDLFAALPDSAKTATNEQDFCSLFVLGVNAHTQRHRDTGDVKGGLAGLVTLGNYTGGNLCLPQLGLKVPYRPGACALLRGSGLEHLVTDFRGPRFFVVATNHETSKKYAWRAMGRLPPLPKRRRRIRAVIDDDDDEDKEAHGPWMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3R1</accession>
    <name>A0ABR1X3R1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672947.1">
        <property type="nucleotide sequence ID" value="XM_066809329.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042389"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="355" mass="41437" checksum="00CCCA90AB63AEF0" modified="2025-10-08" version="1">MPIRAKGWKEALWLWPAQCCCYSIYYPLRGLYLCAKHAKRTPGKISVAWRRHRIKNRKIPKRKPIAKTQQQKNGLAASSPASFLHLPLELRLQIYDLALGEPCLVEPHLGKPEWHPQPCNWRPGQRIRDDDEEPEGDEVRTVLDVRAFGLLYSKKWWCPDGGRHDLERFSRYGVPWTWFRAPCYSKLMRTCHTVYDDLLHRLYGENTISLIGAEMLRYFGRNASPEGLGLVRYVHVGLVVGWQGWESPQEQESFEQAVRSLQKLFPRLEQLDLNVTVAGSHPVKPGELWDWLRKDVLERHLANLQQFRLKVMGYSPGYRSPCLPCPQPWYEQLRTWNEDDYRALKAAICKPSPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4B9</accession>
    <name>A0ABR1X4B9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutathione transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673143.1">
        <property type="nucleotide sequence ID" value="XM_066809525.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042585"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35371:SF1">
        <property type="entry name" value="BLR7753 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35371">
        <property type="entry name" value="INNER MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8090249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="14705" checksum="C7C0737FAF708BE1" modified="2025-10-08" version="1">MVVGAETYGKMLAVNQLDTANPREFHETISKSDKVDKITKGRIMRSKAAASNGYETLPLFTGAVIASNIAGVPVSTINMLSFAYLGGRALFNFIYIRLQDNRKFASARSLVWMASIGCWFTLYIQAGLRAMQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4J4</accession>
    <name>A0ABR1X4J4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673232.1">
        <property type="nucleotide sequence ID" value="XM_066809614.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042674"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="230" mass="25152" checksum="F254EB64F38D32A7" modified="2025-10-08" version="1">MDAIYENDHGQETYKPWLRDRSAHPLEDIQEQVEAALAFLCLFSPTSPWHMRLAQGTAPSPLPASPPATARHQASRRSTPPPLAAPGADGRGHPEDTGGGTDPSPAHADPGREAVADGKRTSTFDFDRVFAHGTDDAAVSDHVAPLVVEGLRFPPWSKRRSRQGPSQANDSVWMKVERPFGTSSQTRSSGVSTAEGKKIRTRRPDYVDLCPVDVSTTIHLEKMEVDRDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7M6</accession>
    <name>A0ABR1X7M6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_001847</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673458.1">
        <property type="nucleotide sequence ID" value="XM_066806162.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039222"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF116">
        <property type="entry name" value="TYROSINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046853161" description="Tyrosinase copper-binding domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8091486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="433" mass="45978" checksum="4B2A171E1C921BAA" modified="2025-10-08" version="1">MHISLASAAFLIGTALAVFTPNLKNGDALAQFKILVTQAQASQAAILDAKAKRAPPPPPPPPPPPPSGLPTPPPPPQAGPKTPAGNSTAPPSKWGKCTKEKLTVRKPWGSLSTTERKAYSDAVLCLQKLPARTPTSLVPGARTRFDDFLASHINQTQTIHYTGTFMAWHRWFTFQFEQALKNECGYTGAQPYWNWALYADDPVSSPIFDGSAFSMSGDGEAVANKGPITLLLGNFAPVVLPPGNGGGCVKTGPFKDMVVNLGPVALPLNNGTVIQGTGLNYNPRCLKRDISAGVNKAFANATSIMQLIGNNNNVADFQLVMQGVPGSGSIGVHGGGHYTIGGDPAGDTFTSPGDPVFYLHHGMIDLVWWVWQMMDVPGRQNQVAGTNTFLNQPPSANTTLDTVIDLFYAGGGPVAMRELTSIHDGPFCYTYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8C7</accession>
    <name>A0ABR1X8C7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673597.1">
        <property type="nucleotide sequence ID" value="XM_066806301.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039361"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="352" mass="38552" checksum="10F1CF2135BF229B" modified="2025-10-08" version="1">MALTSSRPNQVPLRTLGAVAFLLMAIWCFSTMDPESIVAFSQPAAESGFIDWDGGKLKMPDRFYGVEALDQAFRGAMASFAPSTLGYDSISSWQFFQFLVDMGPIYTIWFLESTRALNSWTPAYLPTIFALLGQVVGVGTVVPLFYFLCIAFGPSQTDLARAPRSQSRCQNKLPVVPLIILFHTSVVFAMFLAPDLSARHYWTWAWQLSPLWIGLGNAAAHQALALLGWKGSSSAKQMLGVMGLISAGVWAYTLLFSPHSLWALFVPQAGPQAGLVLHMRKALQADEIGVVIGIFLWMAHCFTELHAGGLIGNEWLFYILLCPIAAFFVGPGAAFVLGWYVRESILEAAGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8E8</accession>
    <name>A0ABR1X8E8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673692.1">
        <property type="nucleotide sequence ID" value="XM_066806396.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039456"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="13"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="399" mass="45633" checksum="F7CA98AD1D7A7F5B" modified="2025-10-08" version="1">MGSTNVTIPATEFPKFPELALELQRMIWNHALDQEGEERLHFYHRGSNRILPTKNNISAIRAATCESRTEALRRYTVELPVIAMTPLPAQPVPDREIWSFEDWVVETADVRWGSRYAEGYEVYINNQRATDLPSSWHTGYVYLDPEADRFAPSYDVSDEDNAEGIVDDAGCGDIVWYGGGFPDLVAYQMVFDFKAAILGEESLHRDEIQRRHISLPLPDNVLNRIRNVVNLDIVPYGKDPDMYRGPVTKRAFLSVWYSEHFRQLQAMVNEPNPRALKCLIPEVESRTVVGKVERRTAECLRIFEIPIVYDPIVDDSEDEDNEDNEGDEDDSDDSDDNDLGNEYDEEDEDEWDAEDDEGEEIAKVKKDSAKKREKLQVSKRLTGTFVVNVVAYVHSYAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8J8</accession>
    <name>A0ABR1X8J8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673759.1">
        <property type="nucleotide sequence ID" value="XM_066806463.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039523"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="444" mass="47574" checksum="C02FD0974564A936" modified="2025-10-08" version="1">MWPMSNALYPGLGNTTDRPLTADSWKSHRGNPFAKAGSTHTRSRRSSRRLSFPRPAGTTGGRSSEDSGDGTEHLRILLRRSQDALNTLAVRSSNEDITGQPGPSGHNARHRNSYQTFGSNADSDQWQDPLWKTLSRQSSALTSSTNGTSADQVVAQPAGTQEPPEYTSDVQSRPAETDVIESSSLESHLVTSETQDQVAKLSTNVSPNVDSPSESSHGDEFEDQQSHTLVRTDTALSRSMLSSSGSQSLDHDSKHDQHSDSESRQSSQGGNAQDVCQKSANVAIAARVTAYEASDADSHEGAHSLFDEKMEEAVASKAKAKRQDKVVKFDTIDEKTIESSSEPGDPEKAEVDHQTTAAPELTGMYDPADGAGLDRQQARPEPAADPGRGGEQDDEPGLLRRAGHGCAFGVWGAGDGVEVGQEPEQGEEQGHYAQQDLVLALVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9J4</accession>
    <name>A0ABR1X9J4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-MPP</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Inactive zinc metalloprotease alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002421</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674032.1">
        <property type="nucleotide sequence ID" value="XM_066806736.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039796"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF49">
        <property type="entry name" value="MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="7">
        <location>
            <begin position="62"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="8">
        <location>
            <begin position="215"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="259"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8092060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="567" mass="61562" checksum="E8AFCF3973257056" modified="2025-10-08" version="1">MFRAHGSRSLRRGLSSSLATASRASQSWTARSQFRALASVSVPPPKETTELDQITTLPNGVRVASEALPGSFSGVGVYIEAGSRFENGYLSGVSHLVDRLAFKSTTKRSVEDMQEAVESLGGNIQCVSSRESMMYQAATFNSAVPLATELLAETIRHPRLTDEEMGEELATAQYEIEEIWKKPELIIPELVHLAAFKDNTLGNPLLCPAERLPEINAQVVRAYREAFYRPERTVVAFAGVPHQEAVQLATQFFGEMEVRPPLSRSGSETSIGSEASASSTSSSTSSWSGVTSKVLPLWSDPVLSPTGTAPVLPTQEALKAPASYTGGFVSLPSPPTPSNPMQPHLTSLHLAFEGLPIDSDDIYALATLNTLLGGGGSFSAGGPGKGMYSRLYTNVLNQYGWVEQCQAFNHSYTDSGLFGITALCIPGKTQAMLDVMCQQLRGLTLTTGFQALGQVEVQRAKNQLRSSLLMNLESRMVELEDLGRQVQVHGRKIPVQEMCQKIESLTVEDLRRVASEVLGGTVVNAGKGSGSPTVVLQDIYDHTTTSAKRMTWEEIQERIYRWGLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9W1</accession>
    <name>A0ABR1X9W1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000047</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674135.1">
        <property type="nucleotide sequence ID" value="XM_066804362.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037422"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF124">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="152"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="277"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8093362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="385" mass="43067" checksum="C26A078D3056568C" modified="2025-10-08" version="1">MSIANGVATVLPTPGGYIVDLDHPRQHTDVATYWIVAVGNALALLFMGQRLYTKIALLKEFRLEDVCLVLAWFTSIGTQAVLVYMFAAELLGARMWELSGSQYNLYHTSPSVVPLDSRRDHGRGARIHPRRLLQLVARLRSRRQELGPDSGGGKCINHDALYAATAVFHIATNAAILVLPMPTLKEFRMSGLQKAGLAVMFAVGGLTVAASVMHLVVLLPALKDKDQPWAMARPSMDLRARKWTCVEANLLIICGASPTLRRFFHYIFTGDEDLRETLTPSPSPRSGMGQGVKGKSSQRRRRRRHFYNRFHDDGCPEYRMRSLHDVDLRPDQIQTVETRAGANSRCSRMWDARPNKSDGDSEKAIFQTRTMTVTYQTRDGSVEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAM7</accession>
    <name>A0ABR1XAM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aminotransferase class I and II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000333</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674421.1">
        <property type="nucleotide sequence ID" value="XM_066804648.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037708"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051326">
        <property type="entry name" value="Kynurenine-oxoglutarate_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807:SF20">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="5">
        <location>
            <begin position="38"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="414" mass="46157" checksum="0BAB0B70BC29FE6F" modified="2025-10-08" version="1">MTNGLPAKLKPAARVTGQRQDVWSIINEAAAASPQQPIVNMGQGFFGYNPPDFIINAAKAALDKVDCNQYSPTKGRPRLKKAIADAYSPFWGRQLNPDTEVTITTGANEGMLSAFMAFIEPGDEVILFEPFFDQYISNIEMPGGKIVYVPLHPPKDGPTTTSSAANWAIDFDELEKAITPKTKMIVLNTPHNPVGKVFSKEELQKIGDLCVKHEIIILSDEVYDRLYYIERLTITVGSAGKNFYATGWRVGWLMGPAHLIQYVSAAHTRICYSSVSPLQEACAVGFEQANGEGFWDQTVKDMRGKIARFTAVFDELGLPYSDPEGGYFVMVNMQKVQVPADYPFPPHVASRPRDFKLAWFMIQEIGVAAIPPTEFYTDANAWIAEDYMRFAVCKEDDVLEAAKERLRGLKKYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAP9</accession>
    <name>A0ABR1XAP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000358</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674446.1">
        <property type="nucleotide sequence ID" value="XM_066804673.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037733"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053042">
        <property type="entry name" value="Mito_GTP/GDP_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46974">
        <property type="entry name" value="MITOCHONDRIAL GTP/GDP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46974:SF1">
        <property type="entry name" value="MITOCHONDRIAL GTP_GDP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="170"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="28801" checksum="B6305E6BA567684E" modified="2025-10-08" version="1">MSPPMVAGKEKESNDLPVSPELMVFHPVDTIAKRLMSNQTKISGITELNKVVFRDTATASVGKNGYTSTADSRSRGTTAQHYSKDFEGAFGKKTGKAIMHSTAGSLIGIGEIVLLPLDVLKIKRQTNPEAFRGRGVMRIIADEGFGLYRGWGWTAARNEYLFALNDYNKASWFQNFVASIAGASASLVVSAPLDVIKTRIQNRNFENPESGFRILSNMAKHEGFSSFFKGLVPKLLMTGPKLVFSFWLAQTLIPAFDTLIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB57</accession>
    <name>A0ABR1XB57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phospholipase/carboxylesterase/thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674667.1">
        <property type="nucleotide sequence ID" value="XM_066804894.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037954"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF64">
        <property type="entry name" value="PHOSPHOLIPASE_CARBOXYLESTERASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="3">
        <location>
            <begin position="140"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="207" mass="22221" checksum="562678BC0F9FE44A" modified="2025-10-08" version="1">MPASSSRLLPGVGPPSTSGNSRTSAPGGRDRAGAGGAKNVVFGGLSQGCAASLVALLLWDGDPLGAFVGMAGWFPYAYRLSNLIQLGTEEDDPFDPFQRDDKDETSPPKRPIDEAVAWLREQIELSCGDSIERVGSASGMTPVFLGHGVLDDKVSVVLGRMARDTLTQLGLQVMWKEYGDLGHWYSNDMLRDLAEFLRCNSLGDTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCL5</accession>
    <name>A0ABR1XCL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001024</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675112.1">
        <property type="nucleotide sequence ID" value="XM_066805339.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038399"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047482577" evidence="7">
        <location>
            <begin position="19"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="348" mass="38450" checksum="855740B0B8D060C2" modified="2025-10-08" version="1">MVMLPVALTFVVFVSIQAVHVGLRALITDDCTPIQQSEANTWAGRHSSLGGALAFLTAYLDLWHGFGRLDKTVFSRASIPTALYLAITIAVTCSFTKERLARSQVQGRKRRPKNLKIMRSIFLGTSAQIRTIYLVQFLNWLGMFPFLYYTVTYVNSLRGNTGSSTHSMGALTPVVYSVVSMFAAMVLPRSALTYSSDSRHWIANFCTARGLWVVSQLCFTAAMLGTFVVSTALPTIILFSVVGISFGINAIVPFSLLGEELSRRRRTGPIPTGRAARILIICTMGFTWHHQSTTGPAGHGDKIAAQDVVWFLRFGGFATLVATYFVTRLEKRKRDEDVVEYVEVPLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCW6</accession>
    <name>A0ABR1XCW6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675313.1">
        <property type="nucleotide sequence ID" value="XM_066805540.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038600"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="497" mass="54893" checksum="951D6CFB326F92BC" modified="2025-10-08" version="1">MSSSDKRRGGSSTSHTNSTLRSSASSRSSGNNVIAPPPRAQLGSRSNSPPPATDNDGGTATNSSSSRGGGVDSDRISIASTLSRDNTTSARENKDAAAQQQQLVREKDDQIAELQRELVQLEAEFARQVELLSQNESETAAFWQAKHSALNQQFLRTDTELRLLRAEVDVRDAERAELKGERAALQEGWEVLQRELRERDDEIRRLHALNRGLKEQVSTSTRALFHEQTSDDQFGDDMARLGNGLQNWIIVHFRKAKIDLAKTSQPEVDELAKFVPMYAELASKIKIHLLQSIVSSVLVDGVFSQYFIGLSEEQSSKFNEMERYLSTTSSDETVNQWRAMTLNMIRKDPSSQSLQSQTDAVVSNLISRVNRLLDSITDATASEARDQALRVLVTSAVVLSRQLAVQKAVFKVTMPYILPHQTVPFDAAEMEDIGGEDEEELTAREICCVTCPSIVKFGDEHGGTRSFETSSLKRECSAAPSDLPASSRDLGIFSPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCY6</accession>
    <name>A0ABR1XCY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675328.1">
        <property type="nucleotide sequence ID" value="XM_066805555.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038615"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="254"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="357" mass="39177" checksum="BF3312ABC0C9AC85" modified="2025-10-08" version="1">MSEDSEDEAFSEPRTPSLDGDKSQEYYAEDGVISLSPPPSPSMSLHSLGMSPLSPLRHSPVLHRSAKPNHHLAAVDQDTQEDLSQDSRDVLVQRLGDLVSRLSGAGELLGNGITNLHARVDEMEHILRQSSSSTAQKGHRRNPSSVDSSSHGGASMLSGLPSPVQQKPPSAGAPSSDPSSDARKAAVPPQSPHQGEPEETSQRRRSHFGDPSDHARKVLRDAEQLHEALLGVVTNLKARQEEQDHIHSLLITRAERAAQRIIYLEERVQELEQEQSEGEMDILNLQIQLSAIEVQCLGYVPEDADPELMESINLWKAEWDAVKRKRALRRGDAAHAFEPPAEQHFRDSAMTSGTSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDI5</accession>
    <name>A0ABR1XDI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675427.1">
        <property type="nucleotide sequence ID" value="XM_066805654.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038714"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="LIPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981:SF1">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="280" mass="30094" checksum="463AAC05DBB305DB" modified="2025-10-08" version="1">MPPLRIASLGSSFAAGPDIPPVSDAKAVRSGANYARLLSARLGGASLTDFAVSGATLRNILDEPQVVDKHTIFAPQIEGLPSDADVVLILGGGNDIGYIGGLFMDSFDAYWVFRLATRVYRWFCPPEPEKEQLDTDALAARYGEVLDAVHARAPGARVLVVEYLTVVGEHVTPGVHVPFDNDPPRRRLAHHREVAEQVRVATVKAVQGRREAEGWCVRVPVAEPSAGHGIGAGQPWVSGWSWRLLFAGGAYHPNAEGMVAVAEMVHRKLLGLGISAVDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE56</accession>
    <name>A0ABR1XE56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675759.1">
        <property type="nucleotide sequence ID" value="XM_066805986.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039046"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="81" mass="8848" checksum="CA12562A885C3EC9" modified="2025-10-08" version="1">MVQPAGTSKAEVGGDAEIVIRRREMYAYGMSLEDHDTPKSPGENSAKLWYLETPTSPGPSIFQAFSVHSLPCAQNAESHRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEB1</accession>
    <name>A0ABR1XEB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Defect at low temperature protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DLT1</name>
        <name evidence="9" type="ORF">PG997_001720</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Required for growth under high-pressure and low-temperature conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DLT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675808.1">
        <property type="nucleotide sequence ID" value="XM_066806035.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039095"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038869">
        <property type="entry name" value="DLT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021:SF1">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="285"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="365"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="412"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8095035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="484" mass="53268" checksum="E7F27450B07D0691" modified="2025-10-08" version="1">MAHPKAKLHTAFRIFYNSVYFLFHLILLALLVAVPGDIIRQAYLYTFQYANIIIISGVYLLSVIIVLFVYFLRLYITRTVLAGIPRSTIPIKKGDVKKQVRQMIAKDLGRSAAIAWEARPKVTGPNANPHTLGIVAEEDNEYEQQHLPDEKIGDEKLRRSPFSWPTLKNPNSPDLPNLQYSTVLSELPNLIEAKAVSQAPVDRNASPDQPAFDPEAVSMLQRAPHMGLRDYVLHLTSLGVIPSATSRTVSDFLDAYERGRFLAEAHVERGVPGPDAPVRRGSAYYAAAEPVHSQRDERQRPRPRPRRHEQHVHRQPQQHRRRRAARVEPDDARGGSIHSLASSSSLSLRTPASRILSKRPAMLQRTPSGVSSWRHQQYGTAPSTPITRTPGPRTPGTGRSGGVGGRLHRAISARSSSTNSNSGGSFAQTRPVYGNGNGASSYGSDGGSSLRRSASQASGGSVIRLARREDGVDLPYVLRIGDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEC7</accession>
    <name>A0ABR1XEC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein disulfide-isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675823.1">
        <property type="nucleotide sequence ID" value="XM_066806050.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039110"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045201107" evidence="3">
        <location>
            <begin position="16"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8095050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="369" mass="40488" checksum="47A33A299CE07C26" modified="2025-10-08" version="1">MKLLVSLCALSVASATMGRRHGWSHISEKDFKLGREEAISGPEYAGSIAACDALRLVWERVEEASNWAISINCVRDQQMCKDYGVISYPAIRLLDSEGKMTPYRGPRTSNAIISYLKRASRPAVTKLEDEQAVTAFQSVDDVVVMAQLHPTRDAHLQTLFAAVADRYWDRASFGSIASISPAAIVCYSNRDRAGEPPSVLSDMTAVDAIQKFVEKCMTPLIGELTRKTEGNPGKSLVYYFSPDALEREEYAASMRAVARKYEEYLLFVTVDAEEYADMVSMLGLRPEVLPAVAVQNPMYGQVFPFDQEKELSAQAIEQFVTQIASGKVKPWDGTPPPPVAAGSTASSSPMESEAEGKHKENGGSTHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQC2</accession>
    <name>A0ABR1UQC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660539.1">
        <property type="nucleotide sequence ID" value="XM_066819654.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052714"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="146" mass="15056" checksum="CFCB36A0F57CA880" modified="2025-10-08" version="1">MSFSNPNDNAVDGSSPSAMSTTSQSGISDVMLDGSNHHPVVTTSSSSIWQPAVSMGPPMNPFSMDMNGSVFPDLMTGAPVSPQPPHKTMNDVYFSTPPPSMSSLSPSLVPGLNTQNLNQTMSFGTGPETPTSMNGTHQGPSPAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1USH3</accession>
    <name>A0ABR1USH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_015216</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8060995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660415.1">
        <property type="nucleotide sequence ID" value="XM_066819530.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052590"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="162"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8060995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="267" mass="28601" checksum="37142474417060B7" modified="2025-10-08" version="1">MNDNDAPSYSYNTATTDLSSGSPHGLDGGWTSSGRASLSYPTTNAYDMPPHRPALVETASYTTSASPYNHMGGLSPSAFPSDSASSVGAENSTRHASVPNTHFTGHSQKPSSSSRKTKRQLPMSPASNTSTTTTGNKSKLRSASRTSKNTHHNPPATEEERKNRESHNQVEKQYRNRLNNQGPAPEMRASSEDGDSNEMSTGDRKVSKAEVLEMAKRYILNLEGNLEATEGERDDLREALDKRRWYCQCPDGGGQGMGGGGSGKGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1USP8</accession>
    <name>A0ABR1USP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660491.1">
        <property type="nucleotide sequence ID" value="XM_066819606.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052666"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="44023" checksum="C0223FA3E2F234F5" modified="2025-10-08" version="1">MAETGMSLTRNKTIGMIMPVGDDLPILSLFDFAEHAENADVPGPTFYATSGWKEDDRRDPQVVDSEKWCSVAHQLASRRVGHRFKTGQRDNGALPASEIQKGRGAACHVEILLSTMYAFSLCEAHLDRRPGQSEEDHVRELLFRLEKIRDMSLGKRRYMVIYIDSYPCRSCIEYVEALGELTGLWMRIRSGCGMGPPLRLGGNRRDVYGEVFDDDDAQRAELEAVMRADPNLMDGHRYRMDQEDTAAAPSGHEETTELDVEDDDDDSPAPEVLFTPPPEPPQHVPPNGNTPLQLSFRNRLSKFVCQPQVQRNLPPRRQPRYIPSIVPNPLDFKPFPPTPVLHDPFTIRAMSDPGDETVVESMEVDDEEEESLVYNNLQFRVSDAWIGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU76</accession>
    <name>A0ABR1UU76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661083.1">
        <property type="nucleotide sequence ID" value="XM_066818895.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051955"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52309">
        <property type="entry name" value="N-(deoxy)ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046971488" evidence="1">
        <location>
            <begin position="23"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="172" mass="19460" checksum="00D7C509E796107C" modified="2025-10-08" version="1">MYFLQSLFKTALLASLAFTTLASPINKGLAEIEVRDTPPLPTVDECKDQLKDGDTLFYSGPSGYASKARQAIKSRDYLEGYEILAQKWKDSNWQNQWQNDEQASKDFFNICSQALAEKAEGTAYVMLPSDTEGTDFHPNTVWTDFEWPHIPDGVKVIRINPDDADDQETIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUL0</accession>
    <name>A0ABR1UUL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HET-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014703</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661205.1">
        <property type="nucleotide sequence ID" value="XM_066819017.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052077"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050349">
        <property type="entry name" value="WD_LIS1/nudF_dynein_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44129">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NACHT" evidence="5">
        <location>
            <begin position="81"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="586"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="628"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="670"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="712"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="754"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="796"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="838"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="880"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="922"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="964"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1006"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="624"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="709"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="750"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="876"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="960"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="717"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1150" mass="127484" checksum="7E712F1E21F191BC" modified="2025-10-08" version="1">MTSNSARDIRTDGPGRVQIGNNYYLQSEANSDRWLPDLRLTDPRDDKSRIEAAKGGLLEDCYRWILEHDDFQRWRHGEGSRLLWIKGDPGKGKTMLLCGIIKELEQPKSETTLSYFFCQSTEPDLRTPTAVLRGLIFMLVRKNELLRRPIQEEYAAAGSKLFNTEQALRRLLTTILEDPKSGSPVLIIDALDECEDLRNLLELVRYFSSEIRSVKLLVSSRNWPEIGDYLENLPQGSSLSLELNQESVSVAVGLYIRNRVKALADLKRCDCQIWKDVEVDLTSKANHTFLWIALVCERLQDVRVRCRHIRQELRSMPAGLDALYTRMLEYIDHSLDTELCYRILSIMSTVYRPLTLPELASLVECPGGFNSDLNTAHELVESCGSFLTLREGTVSFVHQSAKDFLTQKASNKILPLGIHHEHYIMFSRSLQVISKMLYPDPLAAARYSCVYWADHLLECRETAATRGDLKDNGPVDTFLREKYLNWLEALSLLKALPQGVSAMLNLQRLAQTERQASTLFMDRARDACLFLLYSKSGIENCPLQAYSSALLFSPQRSITRNQYKRPAWVTQAPNVDRDWNACQQTLEGHSGSVNSVAFSPDGRQVASASWDKTVKLWDAETGQERQTLEGHSGSVRSVAFSPDGRQVASASSDETVKLWDAETGQERQTLEGHSGFVWSVAFSPDGRQVASASDDDTVNLWDAETGQERQTLEGHSGSVNSVAFSPNGRQVASASSDETVKLWDAETGQERQTLEGHSGSVRSVAFSPDGRQVASASDDDTVKLWDAETGQERQTLEGHSGSVWSVAFSPDGRQVASASDDDTVKLWDAETGQERQTLEGHSGFVNSVAFSPDGRQVASASWDKTVKLWDAETGQERQTLEGHSGSVRSVAFSPDGRQVASASDDDTVKLWDAETGQERQTLEGHSGSVWSVAFSPDGRQVASASSDETVKLWDAETGQERQTLEGHSGSVRSVAFSPDGRQVASASSDETVKLWDAETGQERQTLEGHSGFVWSVAFSPDGRQVASASYDDTVKLWDAETGQERQTTNIGILSSTLSFSPDSSYIFTDVGAIPIGRQPSQSLPLQREATRYGPGISEDRSWITWCGDPLLWLPPDFRPRTSAVSGSLVTIGCSSGRVFFVQLAEGLKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUV7</accession>
    <name>A0ABR1UUV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661081.1">
        <property type="nucleotide sequence ID" value="XM_066818893.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051953"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="245" mass="25434" checksum="A7F45BE4B9F22676" modified="2025-10-08" version="1">MASTGSRSSKKLPAQRGFAYDQNATQQFLQYPEYSSANNEPPAYNGSDFYSYDGYGYSSSVCSHQPPQQALGDIDEGSAFTYSAGDPCLAGIGSNFGGDPSFLLNDALPDPDPLAGESSTAASHIGFETLPGFTLGAGLGQSLPVDRSRDVYRAFLGIPVTSGQDSFYDPHSLDSSVYHGSSSNLGGGGGGGNAGPGLPDHTLPQFRPGAEQQRLQSEAPAKAPQIRPTNTNATFVSGHSTGHGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UW87</accession>
    <name>A0ABR1UW87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10 11">Catalase</fullName>
            <ecNumber evidence="3 10 11">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_015029</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 11">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3 10 11"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661531.1">
        <property type="nucleotide sequence ID" value="XM_066819343.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052403"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821:SF1">
        <property type="entry name" value="CATALASE-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 11" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10 11" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="14">
        <location>
            <begin position="41"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8062932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="740" mass="82511" checksum="C11F151864F50DB2" modified="2025-10-08" version="1">MASNIVSDTFNKAKTAMGVQDAKAAQMQPDIQEPTKDSRITTDFGVKQSNTDDWLKVVSNDHTGPHLVEDVPGREKIHRFDHERIPERVVHARGTGAFGTFRLKESAEDVTFANVLTDTSRETPVFLRFSTVAGSSGSADTVRDVRGFAVKFYTEEGNWDIVGNNIPVFFIQEAMKFPDFVHSVKPEPHNGVPQAQSAHNNFWDFANLHTESTHMQMWAMSDRTIPRSFRMMQGFGVNTFTLINKAGERHFVKFHFTPHLGVHSLVWDEALKIAGQDPDFHRKDLMEAIDNKAFPKWDFGIQVIPEADEHKFEFDILDATKVWPEELVPIRNIGELELNRNIDEFFTQTEQVAFCTSHMIPGIGHSDDPLLQGRSFSYQDTQLSRLGINWEELPINRPVCPVMNFNRDGQGRHKITKGTVNYWPNRFDIQPPASHSEGAYVDYPQKVEGIKQRARSPKFKEHFNQAQLFLNSMSPPERAHMIAAFSFELDHCDDPIVYERMALRLADIDIDLAQQVATMVGGPVPQKESRPNHGKKAKGLSQTEFAPKKPTIESRRIAIIIADGYDVTAYNGVKAAITAAGALPFTIAPRRSEIYPAGSDKKTGSGVVPDHHLEGMRSTMFDAVFVPGGAESINTLSKSGRAIHWVREAFGHLKTIGGTGEATALLKLAFALPAITISQDSTAQASYGVVTMANVSPEGLGEAVTIAKEGASFVQKFFYEISLHRNFDRETDGLSVQVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1Y8</accession>
    <name>A0ABR1V1Y8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ceramidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011930</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661937.1">
        <property type="nucleotide sequence ID" value="XM_066816245.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049305"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187:SF1">
        <property type="entry name" value="ALKALINE PHYTOCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="206" mass="23233" checksum="5EBEC1766DACF34E" modified="2025-10-08" version="1">MGHHNHDFSGDKYALAGVWGPPTSWANFCEEDYGVTRYTAEFINTLSNIAYADELSMLVLATAILHRLYTVGRSPFAKQAATVFLLSTTTGLAVAYVRSGNVMYHVTIFGAQLTCIWPRTLYQIFAAERAAERRAKRLRQFGKAAVALAVGYALWHIDLEFCDLLRSWRRALGAPWSFVLEFHGWWHVLTAVGAIEYIKLVRELCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2F0</accession>
    <name>A0ABR1V2F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative gamma-glutamylcyclotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012117</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the gamma-glutamylcyclotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662123.1">
        <property type="nucleotide sequence ID" value="XM_066816431.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049491"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045038">
        <property type="entry name" value="AIG2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544:SF2">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Gamma-glutamylcyclotransferase AIG2-like" evidence="4">
        <location>
            <begin position="17"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="189" mass="21509" checksum="AB5704AA2983B97B" modified="2025-10-08" version="1">MTNESGNDGTGRTHTAFFYGTLMAPEVFFTVAYRNSPLNVAVLKSLHTFQPAVLHGFRRRRVRYADYPGITRDTTSEDASVRGTYVTGLTDANMFHLDAFEGCEYERENVTVKLLSKVGNDQGEGNVEGDEVECQTYVFLNPGRLEPLEWDYHEFRTQKMRSWTREDYGFDDTDHLAPDEVEEAKDAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2F1</accession>
    <name>A0ABR1V2F1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012118</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. TRA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662124.1">
        <property type="nucleotide sequence ID" value="XM_066816432.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049492"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05163">
        <property type="entry name" value="PIKK_TRRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046807">
        <property type="entry name" value="Tra1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046805">
        <property type="entry name" value="Tra1_ring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF1">
        <property type="entry name" value="TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20175">
        <property type="entry name" value="Tra1_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20206">
        <property type="entry name" value="Tra1_ring"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAT" evidence="6">
        <location>
            <begin position="2672"/>
            <end position="3229"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="5">
        <location>
            <begin position="3515"/>
            <end position="3854"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="7">
        <location>
            <begin position="3854"/>
            <end position="3886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="164"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2024"/>
            <end position="2060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3238"/>
            <end position="3343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2045"/>
            <end position="2055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="3255"/>
            <end position="3280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="3323"/>
            <end position="3337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="3886" mass="442926" checksum="265EC7EACB71B535" modified="2025-10-08" version="1">MALNFEDIVKRLTIADFEAKSKLEAATLLRDSLDHYTGNPVSYPPFLKRVVPLFINVLRGPCLFQNNSPEQKLRNCVLEILHRLPTHQTSPEPFEPYAEEVVDLLMQLVKNDNEDNATLCVKIISDIMRHQPKVLQGKVQPFLTLIQELFEQMERVVREQLDSTAVPSNATGAPSTPGSTQTNFQSPRPGSPVASVTDLGQDLQQQSRPLLKGMQSFKVLSECPIIVVSVFQTYRNIIPANVKLFVPLIKSVLCLQAKAQEQAHAEAKAKGQTFAGVSPNIKNRAAFGEFITAQVKTMSFLAYLLRQYSSQLTDFLPTLPDIVVRLLQDCPREKSASRKELLVAIRHIINFNFRKIFLSKIDELLEEKTLIGDGLTVYETMRPLAYSMLADLIHHVRDALSPEQIRKTVEVYTRNLQDDFPGTSFQTMSAKLLLNMAECIAKMQNKVDARHYLLMVLNAIGDKFAAMNRQYPNAVKLSKLYAQQAADQEPDTYLADKEHRPDWDETDIFTAMPIKTSNPRDRGADPVVDNKFLFKNLMTGLKNTFYQLKTCNLGKPVDPAVIPTHWQEVSYGFTAEEVKVIVKLFREGAYVFRYYEIEKPAAESQYASPVEYMANFYMVSSSKEEKDLLETFATVFHCIDPATFHEVFQQEIPRLYEMIFEHTGLLHIPQFFLASEATSPSFCGMLLKFLMERIEDVGSADVKKSSILLRLFKLAFMAVTLFANQNEQVLLPHVVDIVTKSIELSTKAEEPMNYFLLLRSLFRSIGGGKFEHLYKQILPLLEMLLDVLNNLLLAARKPAERDLYVELCLTVPARLSNLLPHLSFLMRPLVVALRAGNDLVGQGLRTLELCVDNLTAEYLDPIMAPVIEELMNALFEHLRPHPYSHFHAHTTMRILGKLGGRNRKFMTEALPVNYQNYADDPASFDIRLIGSKRDRAFHAEMGIDCAIRKLMDTPKLTTKVASSRQYDGFYKKQALHLIKAQLKLRIGFDSLPDELPRLVRLQAQDFLARKCDNDLSVFDSSDRERSVVKKDEQDQIMKRLIKAIMFAQSLPEFRDEADVFLMNLCRHFTIIEVGRGLIDLKRSGSPFNVKAGEGPLFIDTRILCDAIVESLASDLPEVRDAAFRAIRAVYDSTATIFGPGQQVGRLPFFGHLANVFSHACYEEEWFTKTGGSLGIKYLLTEIDLGPGWVAGKQDNFIRSLVYVIKDMPQDLPERTRNCAQETLEILLKQITRNAKKEDAMFPTPQPGQPPVKPPRLATICVLFNEELSHLNKHVRATARRSLELIAHATGVEIWELLDPLKDRLLTNIYPKPLRALPFATQIGYIDAVAYYMSLKNDFIPFDDSLNRLLMESLALADATDESLAGKPQEFRTHESIVNLRVACIRILSKAMSFDDFSKGQNNPTRTKIVSVFFKCLYSESKPTIEAANESLRAVLSHTNKLPKDLLQQGLRPVLANLQDPKRLTTHGLDNLARLLRLLTTYFKVEIGARLLDHIKNLADLTVLQQISFTFFEQHSQMKVIAAVFNIFHLLPPAAEQFKERLIDTVLELEEKLRRTQHSPFRLPLYKYINRYPQDIWSFLLSKLEDIKYGRFLAQVLSTSDTQGLRDHAASHVDALTKFCGEIVTANKDTKYVTIINTVNVLDALSQFPNAHSWLGRKDIISWLHLIGKDLERQLRSNHLPPHLRLPANQAAEQLMAIFTKALALNTKDLDSLFGLVESVTSDDFRATSAFFSFIYKHVICNESIDYWKSVILRCLDIYSGKQASQRTKCFLLRNIVNPIVAMDIMRHWNQLDQPKPQRLMDRSVIESINAKIWKVNLGDPQEDLAQPGIDHTRMEVLQLSAMLVKYHHAILQDARKDIIKFGWTYIRLDDAINKHAAYVVIGYFIAHYETPAKIVTQVYYSLLRTSQNEGRALVTQALELMAPVLPKRCNASPSDRNAVWAMAPRRILAEEGQNVQQMTSIFHFLVRHPDLFFESRDKFALLIVTSLRKVSAPQSSSNESKKLALNMMWLVWEWEQRRVDGAHNGTARTLSESPNSRKRRLGSDQPISSPPTVRQSAPAKEYQIPDQYRIKMVKYLVEFIAQLNERYRVPSAKPRDTPAGAAAALPPQSTELCKKAMSLLYNLLQPQYWGDLECDLFPNVTEVVLASERTSKILSADPNDKEAYDEKFITNIINTLQVVRTILNFKKDDWIVRNMPSVQKVLEKSLRSDNPELQDCLHFADKEYDDGRTMRSIVQRILDAVPEDVPMEDADAEGEAEAPTSEIVTFLSMIATETLNASNYVSGVNILWSLGQRKPSVIDQHIPALMKALQVKLAREHVTHYSAVTSHQLGVTAVRPADPMAQNGEMSAHELEIQTNLMIKAIEVTAMRMEILGDNRRPFLSVLATLVEKSLSIPLCQKILEMVEDWVFRSEGTWPTLKEKTAVLHKMLSFEHRADPTMLTKFLELVIRIYEDPKITRTELTVRMEHAFLIGTRAQDVDMRNRFMAIFDKSLSRTATARLQYVITAQNWDTLADSFWLAQANQLLFGAVEANSSVQLHHEDFRTLPASLAFGTYIRDNREASAMVDDNYDTFMANHRRFVAEVGDVKLRDVIEPLIQLQHVDTNLAHELWVVLFPIYWSATLKEEKTDLEKGLVVLLTKDFHSRQIDKRPNVVQSLLAGAAKAWPECKIPPHVLKFGAKTYDAWYTALVQLEKAAVKSDGESATVRESNLDALVELYANLKEDDLFYGTWRRRCHFVETNAALSYEQNGMWDKAQKMYEAAQIKARTGVIPFSQGEYMLWEDHWVLCAEKLQQWEILQDFAKHENLQDLLLECAWRSVEMWQNQEHRDSLDHIIKGVMDAPTARRSFFQGFMALLKLHNNRSNETQTEFNRVCDEAIQLSIRKWHQLPRRLTAAHIPMLHNFQQLVELHDANIICQSLASTTQANLDVKSGELKLLLGSWRDRLPNVWDDITDWQDLVTWRQHIFALINNQYLQLLPQQGPNANGASFAYRGYHETAWIINRFAHVARKHNLPEVCIAQLSRIYTLPNIEIQEAFLKLREQAKCHYENPEELSSGLDVINNTNLNYFNAQQKAEFYTLKGMFLEKLKQKEDADAAYGTALYYDISKAKAWAEWGYFNDRKFKEDATDLNSAKQALTSYLQAIGSYKNGRARKLIARILWLLSLDDANGTIASGFEDYKGDTPVWYWITFIPQLLTGLGHKEAPRVHVLLQKIAKSYPQALYFQLRTNREDMLVIKKNQEAKEKARQRAQAAAATNGKPNTSPAQAKQDNPQAKTETGSRPQTAGGEAATQPKVEPSDEKAASATPTAGSVPPPASTDAGDQKTETAAATTATAAPATTGQKKPPWELTEEIMSTLKTAFPLLALSMETMVDQIQKHFKCPPDEDAYRLIVALLNDGLAYVSRMPSSYARDVKLPAATETNITRFAETILPAHIKSSFETDFVSVKPTMYEYIHKLRKWRDKFEEKLDRRNPRDTLERYSKHLSDFRYLKFDDVEVPGQYLQHKDKNQDFIRIERFLPNVDLIRAIGVSHRRITIRGHDGSIHAFAIQHPAARHCRREERILQLFRHLNQTLTKRKESRRRDLQFTLPLMVPLAPHIRIVQEDTSYITLQGIFEDHCRRNGMQKDEPVLFTMDKLRALIEPKGAVSQPLHVDPDSHANTNQKHDSGVNARLEVFTAIQEKWVPHTVALDYFQATFPEFSEFWLFRRRLSYQLSALTFMTYILYMTGRYPHKINIARGSGKIWGSELMSFMAPAKPFFHNPEPVPFRLTPNLQTLMGPLATEGIFSCAIMAIARCLTEPEFELEHALTLFVRDEMIFWFTSSHRAIHLNENQLRDTVQTNCDMIVKRAVSLAASPVGNLPANQTVIDLIAKAVNPINLGQCDALWMPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2Y1</accession>
    <name>A0ABR1V2Y1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme/RWD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012291</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662297.1">
        <property type="nucleotide sequence ID" value="XM_066816605.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049665"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23791">
        <property type="entry name" value="UBCc_UBE2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="32"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="180" mass="19772" checksum="C0050F6028454097" modified="2025-10-08" version="1">MDFESENSQNSAPGSAQAAKLGGSRKGPDAQSVTKRLQTELMQLMTSPAPGVSAFPSADGNLLSWTATIEGPDDTPYAGLTFKLTFAFPNNYPYAPPTVLFKTPIYHPNFDFSGRICLDILKDKWTAAYNIQTVLLSLQSLLGEPNNSSPLNGEAAELWDKDMEEFKRKVLARHRDVDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V301</accession>
    <name>A0ABR1V301_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662070.1">
        <property type="nucleotide sequence ID" value="XM_066816378.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049438"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044980">
        <property type="entry name" value="NDUFB2_plant/fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="52" mass="5740" checksum="87953D336839893A" modified="2025-10-08" version="1">MAGGPGGPIKPHVPGIYRFAATGLGASMWFFLMYRAKKDGPVLMGWKHPWDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V350</accession>
    <name>A0ABR1V350_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribonucleases P/MRP subunit Pop8-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662349.1">
        <property type="nucleotide sequence ID" value="XM_066816657.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049717"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020347">
        <property type="entry name" value="Pop8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049128">
        <property type="entry name" value="Pop8-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28173">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28173:SF1">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20976">
        <property type="entry name" value="Pop8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonucleases P/MRP subunit Pop8-like" evidence="1">
        <location>
            <begin position="33"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="143" mass="15350" checksum="15210A2B6F0FA5F3" modified="2025-10-08" version="1">MAEPGDTSVLATAKAKSQKSHELASCVMKEPLFSYAHLQVLNGNPLQEPIELDALQVRSYCTAALQQFLGIAGTAISIDILKVDGSDCWLRVPRDSLGAFSAAITAWRGTNENGVHTTFQVKGCSDWLGSLVGQVGQDTLWSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3H5</accession>
    <name>A0ABR1V3H5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662484.1">
        <property type="nucleotide sequence ID" value="XM_066816792.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049852"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047324952" evidence="1">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="117" mass="12031" checksum="CE25B98688E5644B" modified="2025-10-08" version="1">MQFSFTAVLFGLVAVSSAAIVDTEGVRNVARQAASGCCIANKSLKQDNCQVNGQAGKCVPGGPAQCGGALNCVATSQLKCDNSVKERSGVLCRFALPNGKIQDGAKQISNLNQAKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4G7</accession>
    <name>A0ABR1V4G7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012836</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662842.1">
        <property type="nucleotide sequence ID" value="XM_066817150.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050210"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00413">
        <property type="entry name" value="Glyco_hydrolase_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121:SF5">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047048919" evidence="3">
        <location>
            <begin position="35"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="4">
        <location>
            <begin position="50"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="396" mass="42332" checksum="99418BE5979D5C4C" modified="2025-10-08" version="1">MHITRRPLATTSVSWVSLLWPLLLFLLHPLPTAADCECGYSTTTTTSGGAESDIVFSELLESDFTRVDYFGDDYKGPQRWARQAFDKTASTARGPFGEAYVTGNARSDIIATTAKNSKISNNDNCGLQLVVGSKVVDGMVQNAEIATMGQDYFHGTYRVGLKVTDVPGTCTAFFWYFNDTQEIDIEFLSHEFNRTNNSYPVNLVLQTAQSRAAGYDASRSDTGTFQKRELPFDPTAGFHEYRIDFLADRVVFYADGTVLAAMAGDGIPSVGGNLLLSHWSNGNPGWSAGPPAADARSVVSYVKAYYNSSNATRGKEARSRCERAPAGARRCRDRGGFFSDPGSGGSDNGGGDNANGQGNNNGDGHRNAASPSVAMGRMGALALVVALGAAICIVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5F8</accession>
    <name>A0ABR1V5F8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662895.1">
        <property type="nucleotide sequence ID" value="XM_066817203.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050263"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="367" mass="41861" checksum="31F20FCB9417AE1E" modified="2025-10-08" version="1">MAGNRLSEEDQQNIQEELVRLSTLLDQTVVQLKNEFKRRDEQVATHAEELEEARRTNDDLAQQISRSGPKELIEPEVLAGEFRSWMTQVTQWAIDHLGPVLEDEDRVQKALATARKEPQRGQVFSRAFNDEPDLAQAAHMNVAVWRVASSCIFRWMKWEVFENSLQPVSPTSFPVVEGMENSLKQFQNAQGIFNPEAFEVWKSQTYQAWSRTPQYQSDRERRTRDLARRLAAGMSMFLDDGGDQNAFSDSHAQRSLAVQNRSKPLTKGIVWAEDTCIDISDNLSEVGPEQTKEFVPIRALSSSSPGLVIRSLVPDGERTPSTILVKQERLVTWGEDYDFDFDMIEEDEGLSFFSRLLRETTNTTPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5T7</accession>
    <name>A0ABR1V5T7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal peptidase complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_013299</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Dispensable for SPC enzymatic activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPCS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663305.1">
        <property type="nucleotide sequence ID" value="XM_066817613.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050673"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009542">
        <property type="entry name" value="Spc1/SPCS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06645">
        <property type="entry name" value="SPC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="107" mass="11679" checksum="141DB1A0BF601C88" modified="2025-10-08" version="1">MAEQILDQVRDLVDGQIDFEGQKLAEIISTIMLSLVGTIAFFVGYFMQDIALALKVGLAGTVVTFLVVVPPWPFFNKNPVKWLPVGGGAAVAQAHQSIVVDEKMFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V660</accession>
    <name>A0ABR1V660_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663441.1">
        <property type="nucleotide sequence ID" value="XM_066817749.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050809"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015:SF22">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="2">
        <location>
            <begin position="311"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="457" mass="50421" checksum="76FEC906470CFDFB" modified="2025-10-08" version="1">MAIIPATAKPIVLICSTPVSGHIIPMMAIAKQLVAAGYEVCFVSGSGYRQQIEALGATFVSVEGYGDFYDLTSWDLDQDWPEGKRHLEGPECFIHDLVHIFCKSLPSQHEAIQKTLRMLNDKHPQRPVVLMTETLNFGGLPTLLGAPGIRPQGFVVIGLNPILLTSVDHPPFGSGMPPDSSPEGRKRNKLANEAQRQVFAPAQAAYTEALLSVGARKPEAFLLDALYTLPDRFVQMCSPSVEYSRSDAPKTLRFAGGYPTMRQTKEPVRPSWWNRVILRKTKKIVFVCQGTVAMDFSQLVIPTMNAFKDRTDVSIIIALGRKYAALPSDVRVPENCVVEEYIPYDDILPYCDVFVTTAGYGSFQRALIHGTPLVMAGTTEEKPETAARGGWAGVGLNLRTSYPTVRQIGEAVDEVLQDQKYKLKALKIKTEMATQNPIGVVIDTIEELVEDQHKVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6E7</accession>
    <name>A0ABR1V6E7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663511.1">
        <property type="nucleotide sequence ID" value="XM_066817819.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050879"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1177"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1107"/>
            <end position="1118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1231" mass="135670" checksum="74484F8AFDC0D077" modified="2025-10-08" version="1">MSSQDQGKTDGGGGPSSPHKPATKKKPSVAEIHNKLLEFSRQNPDMKFTTQDFANALREVARRKQAAELMTNMTGVSVDIASPQLQSTESMAASSSNHDQTTQDKLAQYYNFVAPGSSASAPATSTNFGSTSLDTNQPISIRDNDGRQLGFLMKQQDVDRIAQSPRVGSAGMPTKPNSAPPRLDSVEATGSVDTGSGAGASSDPDVKPTLSPGQTVVSMRPRGDAAEPSASTSSPARALVANMGFAAASIAAGNRKAPPPALNLQQPSKPTPKPKPAANHYISMVAKTATDMQPESMEKVEATMNWGKSPAEQVVMLKSPVATLFWENKKKEQGLPSIMEYSVDPIPQTYQETNDQSNDYTLETPLTAKFAKEQDRIKKEEQAKNEEAASIYQPDVNALFENHKSDGAASKSEKGKKPDSASSKEKPGDAASKGKPDDAASKDKKKKKPTKRTLRRRAANKIPQSYRIHLALTTGRSRPSTRFDMIEQLSANLGLIVEVCKHLPPADLLNLYSVHRTFHETVNRFLRSSIRTWTGYNCPEAALVYNWRSAMYRHLTIPDPAGRPLASPLTPFGFHPYRPKNNVYRPSTSSDNAYLESQGIDTSRRKGKEKMVYSDDNTKADDQEYYVGGDHEMIRLVPTLKWRQQTTSSPTWPATATARPPGTSTSLLKLWKLLATPTNDGRRAIIRSEARNNHNMDCKCWILKAKARLDRGLAVPLLKNLERMAKISALGLPEEIQGFTDLDLARLQCFFLKLDLRFNDPIYGPECTDLSDLMLGQRSLEPLRQLLFGERYRTIDQLIALKIRYDLGCAWTVVPPAPDEVLFRQNWKLMGVPFADWGKTHLEYWGERSGGPLSSICDPHDPTVNRNHMIHVTQLVAEESKRRDLKLEQHLIPLTLWGCIDWKTGRNLHPTESEIYMHDSAHKNRHIDTSQEFTRIEILKGRWGSLSTAERQEKPTDQDEEATAISHAVMQPITGLTAPPEIPKIDVGVLLENVADDSVESPGPLSAELMELERMDYSDFNSDSDSDSEHGLGSFEEGENPSSGTGDENAWKPKTPDNCGHLPQSFKQSVDEYQRRKARATTSAPLSTVGLPMMPHGWTDPTPIPGNGVGDGGAGPAGPAGHDDPIVDQAYINNVLYDMEEQLSDSDESIGFDDSWDYFDWEVAPRYIWSFLDHVRGDGSEETDEEDAGPSNSNSANAEEETVESAWAALQEAEAAAIAAGYRHIQARDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6S7</accession>
    <name>A0ABR1V6S7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012481</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662487.1">
        <property type="nucleotide sequence ID" value="XM_066816795.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049855"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF22">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047285679" evidence="5">
        <location>
            <begin position="16"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="63"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="494" mass="53584" checksum="47184818DC9B4D17" modified="2025-10-08" version="1">MLLSLALSAVAVSSAATLAVRADAGGTACTAIASSLGDAQVAVSPLNASYIDSRHDYWNARQSKYRPSCVVYPKSSQDVSVAIRAIRASGSRFAIKAGGHSPNNFFSSVDRGVLIDFKSMTGKSYDAATTLATYEPGSNWGQLYEFYQQYGRAVVGGRLSGVGTGLALGGGLSYLAPQYGMACDSFKELEAVLPNGTITTASATSNPDLFFGLRGGGGNAFGIVTRYTVQSHPIDKFYAGTLVYVLDHAQKVLKAVRDFIAYNTDPKASVLVTYETLTTPDVLLNLDEVIVVFLVYDGADPGAAFRNFTQIPRLVDTSKPNKTYKEVADMPIPYTAEISRADNIFRIGAHRIEGNAYRDVYDRYAAWADANKGLYVYVSLNFYPVARSMTDASRARGGNVMQMPDGPWFWVNYILSTPPGMLPDLYDKVQASFRAMVEATPSATGLPLFLNEAAVDQRPLASFPTYRRLQQIKQEYDPDGFFTNKTGVGPFLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V720</accession>
    <name>A0ABR1V720_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribokinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013733</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663739.1">
        <property type="nucleotide sequence ID" value="XM_066818047.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051107"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01939">
        <property type="entry name" value="Ketohexokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052562">
        <property type="entry name" value="Ketohexokinase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034093">
        <property type="entry name" value="KHK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774:SF3">
        <property type="entry name" value="KETOHEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774">
        <property type="entry name" value="PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="3">
        <location>
            <begin position="1"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="333" mass="36353" checksum="3D587F5579A490F3" modified="2025-10-08" version="1">MLNLVCVGACYLDTILSVPRFPEEDSKLRATSLSVRRGGNCPNSLEVLQQLLKAQEQQSHKVRPYLISCLPSEEGPASARVKDSFGPDSPVDFTRCIYREQHDQPASSYIIRSEATGTRTLVNYNDLPEMSVHEFQAAIEGLGRQDDMWVHFEGRIPETTLRCIQYLRQALPKASISVEVEKPDREGLQELAAEADVVFYSKSWAESNGYKSAHECLMAQSEVARRASLLLCTWGAEGAASLSLPSKRSVSCPALRPGQTVRVVDTVGAGDTFIAGMLYGLLCHQDDWDADTKVRFAVQLATSKVQVEGFGGVGTHVMGDGGDGPDQKATPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7B1</accession>
    <name>A0ABR1V7B1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663832.1">
        <property type="nucleotide sequence ID" value="XM_066818140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051200"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02140">
        <property type="entry name" value="Frm2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="entry name" value="NADH Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033877">
        <property type="entry name" value="Frm2/Hbn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43035">
        <property type="entry name" value="FATTY ACID REPRESSION MUTANT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43035:SF1">
        <property type="entry name" value="FATTY ACID REPRESSION MUTANT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="FMN-dependent nitroreductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="77"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="269" mass="29735" checksum="7011BB3EC7D76161" modified="2025-10-08" version="1">MRPQLLAVTSSLLRSTTARLYPSSPLAPLSALILGHQSFAVKAQPQYQAQQQVLYTSQTTANMSATPINANSVLDLIKNRRTYYPLSKDLPISKERISEIVKEAVLHVPSSFNAQSNRVIVLLGADHEKLWDIATDILKAIVPAEAFKATADKMGMFKGAAGTVLFFEDEKTVQKQQSDYPYVRRQVPRLGHAVGRHAAVRHLDRARGRGRHRRQPAALQPLINEKVAAEWNVPSDWKLNAQLVFGGKTGEAGPKSQIPVEERVKVFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7D8</accession>
    <name>A0ABR1V7D8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kelch repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663858.1">
        <property type="nucleotide sequence ID" value="XM_066818166.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051226"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="451"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="548" mass="58979" checksum="7F34C9DAA1090AEF" modified="2025-10-08" version="1">MIYGRYILPSRMKASRFVLANLIPRGCSLVKALSDTPYPSSFIRHPFVTVAVVGDYVYFDGGELAQSVDGVVDEKRPSYQLNTTLSLSLSSSWTNASATIRSIPKSAPCQNIPITWFDASASSFYEWGGYTAWGGPAVDNLIWKFTADGSGGGAWSKVIPTNIVAFNNAARLRLGRSHQQRVRDRVAISGLASFDTGSLKWENVSSTGYGKYGTSLRGRMESVPFGPNGLLMVLGGAEAPVGVINTVEMVSWDTVSFVDPGTGKWYSQATTDPRPTRKQMFCSVGVQGPNGTYEIFIYGSMTRASLDEIHVLSLPGFVIFKSPSSGTPRNDHACCRRLPRGLGFPKSELDSDPWKQGLGVFDLTDMVWKSQYNADARPYDTPKMIQDWYAQGGNDLVSWASEEVKALFRSDANKAANPGGGTSDIPGSGSGSSPDNPSATAPTSTHSQAGAIAGGAVGGVAGIVLIAALTVLVLRRRRRARQVGTVQQQQQQQPGEWPKSELPTGTVLQQSHGGSVGQWPRQKMQPWELYSSHGHSELGPGSQHEMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7S2</accession>
    <name>A0ABR1V7S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_013988</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663994.1">
        <property type="nucleotide sequence ID" value="XM_066818302.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051362"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009316">
        <property type="entry name" value="COG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024602">
        <property type="entry name" value="COG_su2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06148">
        <property type="entry name" value="COG2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 2 N-terminal" evidence="10">
        <location>
            <begin position="45"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8067241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="288" mass="31412" checksum="4BEDE651C507CD01" modified="2025-10-08" version="1">MSLKTPMSPSRPISSRTFNLPSSSSSDTDGDDDPNNLPFPTALPRTDFLSPSFDAASYLSSLSDRHQTLEDLRQDLRDRSAAISTELLELVNANYTSFLSLGSELKGGEERVEDVRVGLLGFRRAIEEVKGRVGDRGREIQGLNTELGGVRSEIEKGRRMLELSDRLELLEGRLALDGAEIDSDESEEDEDEDDSQIIGSSATKLATLAKDYKTTQALADDIGRDTPYVKKLAERIAKCRTTILLDLGTTIKAAKKAGASGQEKLLKLMAIYAMLDAQKDAIKALKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAS2</accession>
    <name>A0ABR1VAS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013876</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663882.1">
        <property type="nucleotide sequence ID" value="XM_066818190.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051250"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01301">
        <property type="entry name" value="rDP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8067129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="454" mass="49805" checksum="786DF08BB10772A5" modified="2025-10-08" version="1">MYEKVPDKDAESEAPQPTRPRPHSRALAAFFIALICFGTLLHPVSRAYHPACKAYGHMRPKSVEERVRKILTSTPLIDGHDDFPLLVRYMYDNHIYSPNFTKPFSTTGLPMHVDLPRLRAGLNGGAFWSVYAPCPANGSDFSEANYLPIVQFTLQQIDMMTRLTAAYPRDFSGLPAISSRSALEGLHQIGNSVATLRRFHALGVRYATLTHNCGNIFADAAIREYPEFGKAPPFHGGVSALGRDLVKEMNRIGMLVDLSHVSEDTMLDVLGGRPEKWEGSAAPIMFSHSSAYALCPHPRNVPDDVLKLVKKTNSIVMINFSPDFISCIDENNSNGIPTHYPPNSTLAQVANHITYIGELIGYDHVGLGSDFDGIMSTPEGLPDVAAYPDLVAELLRRGVSDEDAAKIAGGNILRVWADAEAVAVRMQSEGVQPMEDDLPNLKFASQGWINGFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH47</accession>
    <name>A0ABR1VH47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664347.1">
        <property type="nucleotide sequence ID" value="XM_066815057.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048117"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="226" mass="25783" checksum="1C59355B938EB785" modified="2025-10-08" version="1">MSGTFTAREQQLAIIAWGYFETEPKGSWSSSRTMTWGSRCSSAKHQPWFKIPGTASLLTSIYMYSEIYCAKEGKPVPAYVTLCGHWEPQMFAGPNCEHFLHELSKTHHLLAWKSSEDPEAEKAVPFGWPYSWGSFFARRDFNERWPLTFLGQKKGFLQAVLRESWQRPYHQHAICPSCAHDDAGLVPLWQSELRGCAVHDIWCGRKEFYLLTPATFLLPCLGLSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHN2</accession>
    <name>A0ABR1VHN2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Brl1/Brr6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664195.1">
        <property type="nucleotide sequence ID" value="XM_066814905.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047965"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040202">
        <property type="entry name" value="Brl1/Brr6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018767">
        <property type="entry name" value="Brl1/Brr6_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28136:SF1">
        <property type="entry name" value="NUCLEUS EXPORT PROTEIN BRL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28136">
        <property type="entry name" value="NUCLEUS EXPORT PROTEIN BRR6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10104">
        <property type="entry name" value="Brr6_like_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01042">
        <property type="entry name" value="Brr6_like_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Brl1/Brr6" evidence="3">
        <location>
            <begin position="259"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="491" mass="55174" checksum="7C1910DF511F59BB" modified="2025-10-08" version="1">MERRTYESPMDWAYENNQGPMDPTSPFVRPLQNAQRTSEHPEASDAPALSLPSSSPLLTSQPTTDTAFGATRPGAFAANSTPNLSAPTQTNSPSKAQASSSSNHYNAPPASTPAFQRTATAPAWRNPSFTTPRKPFDMDPLSEVEDSPVATDVDASFADDSNLYEPDTPEDNSRSLRHMSIAPARSKTMFGNNRDKIRKRKRRHDDKDISGYRLPYKHVNEWEESEDPDSDDSTYEPNEHPHGPRSQRVPGPPQAPQILGYWLTLAFNASVLGFALWILFNIYGAFRHEMSLISQDQTTSITDEIVACQRNFDQNRCFPRESRLPALAALCDEWEICMHQNPVKNYSVRFGARNMVEIANTIFESMHWKTMVGRLLHPHHDPLHERRGPLQDVGAPSFTTAVPQHSQAASSQHSQQHHYYYYPPRTPHRGGSSYALMNGQDETPDTDASPESMARPQLLPPPYETPGRRRSPSKEHRARSPTKSRSPSKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI36</accession>
    <name>A0ABR1VI36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664700.1">
        <property type="nucleotide sequence ID" value="XM_066815410.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048470"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="584"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="753"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="763" mass="83867" checksum="F7C1A90060B3DDAC" modified="2025-10-08" version="1">MQKFVVDRAAALAQLRGRRPYPSCLINIITTFRGEAVILSPSHTPGSTAAKLTEPIPPSSFHDRHDLHETRPTPTQIYQRQQQQQHQPRLSHARQTQTPPPSVPEQTPTPSSHHRALRRTPRFTATPSPKPQDPSAQQPSSARVTLTLGPQGKFVLADQQQPQSGQPQTRPRPRPARRQLSQDLSSEEDEDHEPSPRAPSQYHRETTDPQGPGLPDPHPAVRISKRTHSAILYALEETLRGPKELSSDWVEELASMSDLLGGGGIATTNGHGASSSRPVPARAPVGSPSGIRGPRMIMQERQAREAARKEERERQEREHAENEARMLEEARRREQERKAAAGGGLGTVPADPNLARRPTGTAAGSGRVPANTGTRTGDLPGGADVETPRRHHRTTSSTAPAQASGAPPGGATAGSAPKTQQGSGADSLTAIGRGRNSFPHAFERWETLSAHWEGLTSFWIRRLQQNSEEINQDPLSQQLSRQVTDLSSAGANLFHAVVELQRLRASSERKFQRWFFETRAEMERNQEVTAMLEAALEEERQTRAEAIREATENAQGSSKVQKQLSEMRKELQISKEEARRAWEELGRREQEERDRTASLQLGHPTIVGGVQVVPMTQGVSRHNSQRDPQQYGQPDPSDYSRGQASRPDYTQAPAVQPVVTSAGGAPYQQPPAVHHQDSYGSEGTFSEEEYETPATQPGAPQPPNSGAQQPPYSSAPDYSGAGFSSSTWEQMPRHHHPTRLSDVIEEDDERSRTSASHSQVSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIA9</accession>
    <name>A0ABR1VIA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664772.1">
        <property type="nucleotide sequence ID" value="XM_066815482.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048542"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="96" mass="10116" checksum="73237E9E23CD8BC3" modified="2025-10-08" version="1">MPADLNGCCECDRKAGAAMAAVVMDLVVVAFGEAVVAIDEGNGLARFDVNAVALKEDLTGLLEPGLNVELCSLFMLCGAWTQRLGGGRMGREKSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIK8</accession>
    <name>A0ABR1VIK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664879.1">
        <property type="nucleotide sequence ID" value="XM_066815589.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048649"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021822">
        <property type="entry name" value="DUF3405"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11885">
        <property type="entry name" value="DUF3405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="721"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="770" mass="87807" checksum="280070A84D85E7A5" modified="2025-10-08" version="1">MDKVSSFLRKSSSFGSMISAKNEIYLPVTTKPQSKKFRLRQILGHCLYRRVVIWTLVLILLLSLTLFNPRLTTKTRQDVMDLVQLGKGQLREAQAGKGEEIVLQTQDGAVPEEKKENVEEQKEEEEEPEDDGQNGPHWMRYKHMDGYYKGLRAIVPFAEYTPEYPAPTGSKPTIPVSAPHHTKLPTPTPYNPHPDYDSSEYKSEYHKVQPCYLDAARKTPVPDVYAYSGVPQGQAKPAMGSYDLLGMREDVCFDRFGRYGAYGLGYTTKEGGTGEALDTDHEGNEAVWEKHGKINWENMDWAAAQERCFVANENRFYTGNSTQDAEYAKLRPKRIDRTAIVIRTYVGFKWTAHALLNFRAMISELNLQSGGEYDVHFLLHVRDNNMPIWADPQTAQDILDENVPREFHGICTLWSEAQMNLYYPGDFGDAFDNPSNGDIHGVYRSAHMPLQHFAQMHPEYAHFWNWEMDMRWTGSYYELFDRLGKWGAKQSRQGMWERASKYYIPALHGDWNNFTKTVERETQASGRRSIMGPVIFAGKNNLQQGEGGFMPKSCATGSDMTQCGVGEDADLITLNPLFDTNESGWVFASDVTGYDKQYPIPPRRCAIVTASRLSRRLLSAMHEETWRMHHGMFSEMFPPSMAFHHGLKAVYAPHPVYVDRAWPAEEIEKHFNGGRDHTSGGHGSPFDLQNEHNHKGTSWYYNSEFAGLLWRRWLGYAQMDGRGKNGGRSGEGDLRGGREEEADPNSSGRLCLRSMLVHPIKWENPSERDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ13</accession>
    <name>A0ABR1VJ13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fusarisetin A cluster transcription factor fsa6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011330</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664935.1">
        <property type="nucleotide sequence ID" value="XM_066815645.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048705"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="296"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="62"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="598"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="687" mass="77855" checksum="485E3EE3A590CB5B" modified="2025-10-08" version="1">MRKMRQEWGGRFLRVCPRAARKPKGNESRPQVDSRPKQDTMSRPLLQVRLQKLEDMVNGLVQNAGSQDGSIASVASSSDPRSEVEMRSDFSTPPSTVTTAVTSNSGAPYGHTQPENGYVGATHWSAILETEPSEEDSSPSPPPQSSSSHQTREMDVVYGTQVRLTVDEAFARLPPKHKTDQLVFGYFQSRFHAAPYIHTSKFQREYDVFWRDPSSASLLWLSILASILNVAATVSMGKGEDVSKDCEAAHPDKLAALAVDCLIAGDYLAAKPYSVEALLLSNYTEFQRRKDCDSSLWSKFGLLVRLAQRMGYHRDPKYLPSITPFEGEIRRRAWFFIEVFDCMFSFQLGMPPIVREDECDTEAPGNRFDLDFDEHTTVLPPPRPPTEATSTLYLCYKSILCRLQRRVIRFALSIQPPPPYEEVVNLDSEIHSFHEQLPATLRIRPVRSYSFADSCFDIVHRLMVELMYLKTLCVLHRTFLTRDHKDNPRYAMSRSTAIDSALRILDLHAEYDEESRPGGRLYQDRYMFSGQTLHDFLIASMVLCLDLTESISTDPAERSRKLKALGTSYKIWSARKHLSPDAAHATRVVGAILRRVSMQEQPTRPPVQPPPQPEVRDGSLASLLNNDTQETPPPPPPPMDQSQLIHAMDFSLDFMDTIPLDNVLNDPSQYDWNMIDHYLLVDRPTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJE6</accession>
    <name>A0ABR1VJE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011574</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665179.1">
        <property type="nucleotide sequence ID" value="XM_066815889.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048949"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8071371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="474" mass="53997" checksum="D40260468F8C8328" modified="2025-10-08" version="1">MSSSAVEDAREKKSVRRRLRELIWDSLDRSPEERRFISKIDFYILSWAGLAYFSKNLNQNNVEPRPANAYISGMKEELNVVGNEYQTFTTMWTISRLRSSAPEIIEARLLTCTKADVFTQVRISIWCPSWELLWVLVTFTTAAVHNSQHLYACRFFVVGTQNTVHQVPTMPHLNPSNPVCLTELGKRACIFFASAFIGSMFSGYLQAALYSGMNGVGGLSGWRWLFIFDGIITLPMALWAYYALPDLPSNTRVRWLSPEEKQLALDHMKRAGKQLDEPFTLAGLRRILGKWHFWVYTAYYTFFICSENIGTYMNLWLKSLNRYTIPQINNFPTATNAITIVTTLTYGWVSDGLQIRAPIVYFSLTVCFFAAMNLAIWDGVPFGLKWASFYMTGQTMVNEYCAGDSLERKFILGTTNSIAYAFNAWIALVTYNTNYAPRFLVGNSVTAGLIICAATTLTAAVFLQRRDDRVDDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJS6</accession>
    <name>A0ABR1VJS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665309.1">
        <property type="nucleotide sequence ID" value="XM_066816019.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049079"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="151" mass="16334" checksum="CCFC6B3A2C91FD76" modified="2025-10-08" version="1">MYMNWTGNPAMESSEHTNGLDEYASGTFTGQNTTSPAPQQQYPGQSYYNQAAAVDAGASHGQGHQFDYRTAPDSHQMWMPAMQTQQQQQQRPTASPGPGNFPSNASWQAASNTPPQAGFAQPAIQQYNVPASHAGYPQAPSRTHSATPYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKR8</accession>
    <name>A0ABR1VKR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinase domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010661</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664266.1">
        <property type="nucleotide sequence ID" value="XM_066814976.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048036"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF0">
        <property type="entry name" value="CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="43"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8070458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="391" mass="43713" checksum="3496B4D0854AE084" modified="2025-10-08" version="1">MGSSPDAGTGMKARRLSLSLPDDFTVDVAELLKEFEYQHKLLGRHGKHLGKGATSKVTLMSRKGSPGEMYAVKEFRSKRSVESEKDYQKKIKSEFSIAKSLHHPNIVETIRLCTDHGRWNHVMEYCSEGDLFSLVSKGYLTQEGREVDRHCLFKQVCQGIHYLHSNGIAHRDIKLENLLITKDSKLKITDFGVSEVFSGIHPGLREAGGQCGQGMNGEIRLCKPGICGSLPYIAPEVLSKQKDYDPRPLDVWSSAIVMIYLVFGANIWEKAEWQNDSKSAGIQGPRGRQGLLPHVDAFDICVKPLALRRLLLKMLNPDPAKRLTMAEVVNTRWFKTIECCQMDTYDDPIKFIDASKKNATISSAGKIYCHNHLPPQNHGHGLPPMPGKAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT91</accession>
    <name>A0ABR1VT91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665410.1">
        <property type="nucleotide sequence ID" value="XM_066813448.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046508"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="35783" checksum="A55BE6E1476EBDC5" modified="2025-10-08" version="1">MENMNTVEVDIPVEAIQAVDPAVVEKLPPGSQIESISAHGASFWTRTARIDATLNGAKQSYFLKTCFGNRGRKMVASEYHCMNKIYAVMPDLVPKTIAWGSYSGIPEVHFFLAEFRPMKDGIPDIERFPAKMAELHQYFTRTTKALLELELETRGESKEIRELMVPFFSKVIPRLLRPMETGGRSIRPALIHGDLWHGNASTDGETGLPIIFDAASFYAHNEYELGVWRQPWNEIKEPYRMRYHEHFPKSQPEADYDDRNLLYSIRVNILDSILYKDDPSYRDMLIGGMKDLVEKFPGGLEEWERAQMASMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTF2</accession>
    <name>A0ABR1VTF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665491.1">
        <property type="nucleotide sequence ID" value="XM_066813529.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046589"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="468" mass="52918" checksum="0002BC284E889FEC" modified="2025-10-08" version="1">MGDTLQGHGLFTASERLAALAGDSARLARARNRFSESPPSYRSQLSGTTTRSQSSDPPTEEQQRYDERVAQLMIEHRASWPRTQWRDEALEEGHRILQARVEEGTFVHVPDSTNLPPSEFLKSARAVVKERWIEQGIWNDEWGPGMPTGLWKHEEPLDTKSESDSENDPETQARPLFSAAATSETPKSEAKLHRLAERQLVREREREASRPFHQFVYQVSAERERIRSKRKPSEPNSLDQADINTKAYDNVKSIWVKRGIWYHRWGILPGMSWKHEQNLDAMLLEELGPRPETGAERDGSEAREENMTPRPIFGPADSAAPDIPDDPPRLLADADELGLQSSNRDHQIPSPTHQTRSGESRGDEGPSATAESLWRSNEAQPPRRGRARRTTGMARGRTNAPAKVSKPQPKKTKLKPRRGKKASVEVPPEPEPEQPQATLDRPEPPAAYTPETPRRSRRLQTRSTTKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVE4</accession>
    <name>A0ABR1VVE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7492 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665737.1">
        <property type="nucleotide sequence ID" value="XM_066813775.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046835"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055915">
        <property type="entry name" value="DUF7492"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24320">
        <property type="entry name" value="DUF7492"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046773320" description="DUF7492 domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7492" evidence="3">
        <location>
            <begin position="21"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="375" mass="40291" checksum="437EFD3C5E227734" modified="2025-10-08" version="1">MSFFNFTHVLVLLTLVRAAISHSWIEQVFRMNSDGSFADNPGYALGYMPRTPDFSDENVQNKIIDPKSNPPVCRQFSQGDYLNSNYNPLQAAAGDYVALTYQENGHTTDPELTSRPYRGGLTHVYGTLQQKAGDKLNDVQKWNADQTGGNKKGKLLATHYFDDGQCYQDRGAAGPQFPIFMERKGKYGLGSLNCQTDVQLPQDLPESGIYTMYWVWDWPQKPNEVGYVPEMYTSCIEIKLGPASAKASCYPWHRHSISPPYTGPTAGSGNGPVASASAPAPTPTGNGSSMPSPTGANGIKTVTVTADPTTVTQYKTVTAGSGNQQTGPATASTLQTSVKAGSSAAAPTNNVPVSTVTPFLKVRATGKARRDASAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYD3</accession>
    <name>A0ABR1VYD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein mS38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009848</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mitochondrion-specific ribosomal protein mS38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666125.1">
        <property type="nucleotide sequence ID" value="XM_066814163.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047223"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="Ribosomal_mS38_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035">
        <property type="entry name" value="AURORA KINASE A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08213">
        <property type="entry name" value="COX24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein mS38 C-terminal" evidence="6">
        <location>
            <begin position="308"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="321"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="342" mass="37901" checksum="016FB9E1228DEEB9" modified="2025-10-08" version="1">MLPSSVRRVVAAAPSTPLLANFVPNAARATAASSIAFPRSQQRRRYSSSKPSSPSDSPKGLPTGQVASSPAQASKSTGEKRGRRKAKDSADAQGTLPAVPSTHHVPKESLALSAFFSLHRPISVTQSFPKTINDDAFAQIFTPRSKDAKYNDVMSTLTRTVEELEQPMSGMGLGEQQESAMAEAENEGMQKIELRHPDGSESSFYIQLNAMAGQFVPFRPPPLPQAESAVSAEAEAGAEKAAEPEEQHRIYKAVLTLEETTDANGEVRIVAHSPKLIEERTQPQPFLSRMAVREWRREEVRGRADKMVAISVRRQRKLKMKKKKYKKLMKRTRNERRKLDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZ75</accession>
    <name>A0ABR1VZ75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666169.1">
        <property type="nucleotide sequence ID" value="XM_066814207.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047267"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="624"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="731" mass="81755" checksum="89B3E69A5885010F" modified="2025-10-08" version="1">MSTARIRRLLSQRQPQNTDGVGYSEYNDKSPVKPSRKESWFASRRPQSRKRPPTPIIISRPQTLHDVRVPLPPLPTGTPQSHSSTSSVCSCDQYGEFASPRAAGLRRSPLCSISSTTITSTTRDKDDWSDHSFRLSSATSYGSEGPSFLSPSKEPERAQRLVPHKTIGSGSSSGSMAALSSQPPEHKEISPVQEADNKETSSDLSISIQRLVQETDEAFKAVGSALAESKTMYNSFNETPKLPPLHLEQESRPTTPKTRKPSLKRPSYSPYPKVAAPPILERKSSVTKPKRNTSKRSKQMKPQRKAVAVKYVPKQLGTRHKISENVSGLFSGRRFKKIEPDEMLTPTQIEQYKLQRLSKLKTETFEDATLPVESESTDTPVEPFHMDDLPSRIGSSGFKLTTDTPVDDKPDPNPFGEPAKRDFSIQRRDDELFLGGMPDRRTPSNTSDEKSSKHASFPAPPPKSQLRGVPRKQLPALPAIPELTVSSDVGDELFIGTSLSARDSEYDKDYVFLRSSPCTITMPLFKHGPIRLSKSDLIPDPKLGVEEGLDWTAFQMAILGGAGDWFSDSEDTIRQREAEELNELMDWWDEWHFENAGGLVTQEEEVSSPTSTESVDDYSEFSYSDIERDNPYSPHHRWQRTMQKAADEGRSLELSMPPRAASHGFWDENEKLYNGGGIQRWTTEGGKPARGEPAQHAAEPDARLHPRHERQRRRGLCAHGLQPGTRPRRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7H0</accession>
    <name>A0ABR1W7H0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal cellulose binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007236</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666893.1">
        <property type="nucleotide sequence ID" value="XM_066811551.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044611"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF2">
        <property type="entry name" value="CELLOBIOSE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G17620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046853143" evidence="5">
        <location>
            <begin position="24"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="6">
        <location>
            <begin position="790"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="226"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8079418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="826" mass="87809" checksum="58C8E75F30F1A165" modified="2025-10-08" version="1">MGNFVRLLSLLAAVGSNVRQAWAQSGTPTHYTDADTGIVFDTWPVSSSMTFGVALPSDALTVNADEFIGIFKCSSTSATEDGWCGVSMGGPMTNSLLLMAWPYETEVYTSFLWATGYDQPVQYTGDAKLTQISSTTGDDGFSVIFRCQNCLSWNQGGSTGSASTSTGVMVLGWASALTNPTNAECPAKVVMKQHEAQGIFGAQLDSSAANPSYTQWTALATKTVTGCGGSGGSPPTTTSSSTAPPTTTTAPPTGVPVPTGATYDYVIVGAGAGGIPLADKLSESGKKVLLIEKGPPSSGRWGGENKPAWLDGTNLTRYDVPGLCNEIWQDSAGIACTDTDQMAGCVLGGGTAINAGLWWKPYTADWDYNFPSGWKASDMAGATSRVFSRIPGTDHPSQDGKLYLQQGYDVLATGLRKGGWKEVTANAANDQKNRTFGHTAYMYSHGERGGPMATYLDSASKRGNFKLWMQTSVKRVVRQGGHVTGLEVEPYLKGGYQGTVNLTPVTGRVILSAGTFGSAKLLMRSGIGPQDQLEVVKASAADGATMIKSDDWINLPVGYNLEDHTNTDLVVEHPDVVFYDFYEAFDAPNVTDKNLYLGGRAGILAQAAPNIGPMMWDEIKGADGIVRQMQWTSRYLGRGATSRGRMTITPTLNTVVSTVPYLRDPQDVAAVIQGIKNVQAAINSQNIPGLKWMVPSPDQTVEDFVNNMVVATSNRRANHWIGTSKMGTDDGRKSSGTAVVDLNTKVYGTDNLFVVDAGIFPGMVTTNPSSYIVVAAERAAERILALPAVKANARYGQCGGRDWTGSYVCAAGTTCQFQNPYYSQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7S8</accession>
    <name>A0ABR1W7S8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667013.1">
        <property type="nucleotide sequence ID" value="XM_066811671.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044731"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="118" mass="13018" checksum="5E545BCFC052386C" modified="2025-10-08" version="1">MYSQALRTASRSGFRVSAFSAPAARPISTSAVRMGSTDRSHAIGESAVPGKIQEKAPQGCRGSSSRLRPPHRREPRLRQQDSRKGRRRRVYPSQKVQEIVPESVEKAVPNALHNTGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7V7</accession>
    <name>A0ABR1W7V7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_007389</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667046.1">
        <property type="nucleotide sequence ID" value="XM_066811704.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044764"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="68"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="167"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="306"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8079571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="397" mass="42966" checksum="337610D5BA3C334E" modified="2025-10-08" version="1">MPPSLGAHDAAMSEASGTREPHADSIVSKMDGVVKKAGSAISGNKRLEDNTDSMVAAKSKRPDKHSMDYMVRSGIAGGIAGCAAKTSVAPLDRVKILFQTSNPQFAKYTSSWVGLARALRDIYGRDGIMGLFRGHSATLLKIYPYAAIKFVAYEQYRAFIVGNRAQETWGRRFTAGALAGVTSVFFTYPLEVIRVRLAFETKHRSSSLVDICKKIYHEQPTPKATPGAAHGVTSVASATAAAVTPRNGMINFYRGFSMTMLGMVPYAGISFLTHDTMGDLFRLPSIRRHTTLPRPANAPTDKPAPLRAWAELTSGGISGAVSQTVSYPLEVIRRRMQVGGAVGDGHRLRIGETVGLIFKERGLSGFFVGLSIGYVKIIPLSAVSFYTYERMKTVFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W939</accession>
    <name>A0ABR1W939_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007827</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667484.1">
        <property type="nucleotide sequence ID" value="XM_066812142.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045202"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052250">
        <property type="entry name" value="PDI_TMX3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426:SF1">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046026979" evidence="7">
        <location>
            <begin position="21"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="675"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="19"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="252"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="171"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="195"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="729" mass="82544" checksum="1FF8D4AF8F6F2460" modified="2025-10-08" version="1">MRLASFALLLGASVLGAAQAIGASAPDDVAKENTHFNGKKVPPLLELTADNFDKEVNVTKYLLVKYYSPWCPHCIDFAPTYQTLYEYYYTSSAPASASQEVKSADSPFERHYDIRFATLNCIAYGDLCTKHEITSYPQTTLYKAGKAVDLIKGGKPMKAIAGLVEKELEASFPGTRPKELNLPEPGATNSPDATTEAKTDKKDDKKADKNADKKVEKADKPSELKKNDKIPEPAVVEKKPITPTKPTWDPPNPFGTKAAKPTSTPNQQGLSVALTAESFQKLVTMTQEPWYIKFYAPWCHHCQAMAPSWAQLAKEMKGRLNIGEVNCDAESRLCKDVRVRGYPTVHFFRGGERVEYDGLRGLGDFVKYAEKALDICGGVQDVDAESFKALEEKEDVIFVYFYDHATTMEDMMALERLPLSLIGHAKLVKTRDQALYDRFKITTWPRLLVSREGRPTYYNPLTPREMRDTRQVLTWMKSVWLPIVPELTASNAREIMDGKIVVLGILNREENESFLQAKHEMKMAAGEWMDKQVQLFQLERADLRAAKQLRIEEAEDRNDQRALRAAKSIRINMDKSDTKEVAFAWVDGTFWQRWIRTTYGIDVKDGERVIINDEDNRRYWDQTITGHHITPSRTSILETISKVTVSPPKIKPKLTISSFEKVFFDMRVTFTEHPYLSIGCFAGLALGIGSWLRGRLRRNRSSFRLEMDNLPIKELKDTFLGNTANGKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W964</accession>
    <name>A0ABR1W964_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667510.1">
        <property type="nucleotide sequence ID" value="XM_066812168.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045228"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="37721" checksum="7FE9563D8B380E18" modified="2025-10-08" version="1">MEAQTQVRPRAQAGVSSPQLLPPPPSFDEQRIYNAMNEEERHQLDAMTEGPDQLADGEQGPSWWDMLVFTSNLVHRLENESPEQLYAAGTPVPTQISTAGQQPPQSHGESTEPESPSSTSSESPPFDNRQRHTRTPLPGRRRGGNPRRSPTPSPFIAQAGPSAPIAAAASTDPAVPAAPEAPSPNTEAAPTQPPQPTAARLSKLSEKKKKRESTGDGGQSKERNTTENENMLAKKIKDEGIANPYGPCSKCVTTGGTCWVLVNGESMRCAKCARQKSRCCFPKQYEDNPDIINNLRSRAMEAEAAAAAAAEAAASQADTQSYLPHHQNPEGSTGPEIPNETNLDETNEFPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9Q3</accession>
    <name>A0ABR1W9Q3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667682.1">
        <property type="nucleotide sequence ID" value="XM_066812340.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045400"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF80">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="70"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="26742" checksum="BEB618E5F0FA755A" modified="2025-10-08" version="1">MPSMLATALQNTCIKAAANLTAQLASRWHAEGTPEPLDKQRILEFAFFGFIGALIGYEWHHGLERHFPTRTRTFKRHRPTASHNLEKGRDPEEKPAVPEPAGGSGSGSSNGGGSGGDLKINYRNVAAKLLLDQTVSLSLMITLFLIVTNILRLPTLALVFGVVRRKLWGLLRAGWTIWPAVGLVNFLWVPVRSRVLVASCVGFGWNIFLSVMAARHAEEHKTMGLSAVGVGGTVAAGAGMGVGVGGGAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9S2</accession>
    <name>A0ABR1W9S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein S-acyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008031</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667688.1">
        <property type="nucleotide sequence ID" value="XM_066812346.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045406"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="5">
        <location>
            <begin position="28"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="7">
        <location>
            <begin position="383"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="6">
        <location>
            <begin position="642"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="858"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="891"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="924"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="957"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="990"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1023"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1056"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1089"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1122"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1155"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1188"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1221"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1254"/>
            <end position="1286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1302" mass="143405" checksum="2E141FAE6A38FE49" modified="2025-10-08" version="1">MVIDRQTARDQADGNGTKPQLANEAYTVGWICAISTEYVAARAFLDDEHESPEHGAQHDNNSYTLGRMGKHNVVIAVLPDGEYGTASAATVARDMLHSFPHVRIGLMVGIGGGAPSVKNDIRLGDIVVSAPRDGRGGVFQYDFGKTIQDQTFRETGFLAQPPTVLRTAVSGVKALYEQRGHQIREDIDTALKMWPRLRKKYRQPDESTDRLYLNNIIHPVNDESCATSCSADTSALVLRRVRDEDDDTPAVHYGLIASANQLMKDAVVRDKLAREKEVLCFEMEAAGLMNHFPCLEWQGYAAMTAAAYARDLLKRIAPNKVEAEGKLSELLTNVSTAVSTMQKHVIYNKSVLDRKEDREVLDWLTPLDYGPQHSDYLRRRQPGTGQWLLDSEEYRTWLGTTHQTLFCPGMPGAGKTILASTIIDNLEHRFRDDRTSAIAYVYCNFKRKDEQKIEDLIASLLKQLAQVRPSLPVAIQQLRDRHAPKRTRPTLDEMSQALRSVVSEHSRVFIVVDALDECQTKIHLLATSRVIPDISEKFEGSPHLEVRASDFDIRRYLEGHIAELGAVITEKNDLRDAIMNSITEAVDGMFLLAQLYLESLQGKDTPRAIRKALSGMVPGAQGDIAYSTAYTNAMERIKGQLTDWARRAKQVLAWIACAKRQLHKVELQHALAVERDELALDPENCPRIEHLVSVCAGLVTVDEQSGTIRLVHYTAQEYFESTKTRWFPEMELEMTAICTTYLSFDVFATGFCESDEEFEERLAEHPLYAYAAQNWGLHARTANTNDPVLDGVLSFLSRQAQVDAASQALLASEISYKYGGYIQRALRRTGLHLAAYFGLVRAVDMIGDNHSVGVKDSAGQTSLHVASSRGRLEVAKLLIEKGADIKAAENDGRTPLHWASWGGHLEVAKLLIEKGADVKAAENDGRTPLHWASNGGRLEVAKLLIEKGADVKAAENDGRTPLHWASWGGHLEVAKLLIEKGADVKAAANDGETPLHWASWGGHLEVAKLLIEKGADVKAAENDGETPLHWASWGGHLEVAKLLIEKGADVKAAENDGETPLHWALNRGHLEVTKLLIEKGADIKAVEINGRTPLHLALNRGHLEVAKLLIEKGADVKAAANDGRTPLHLALNRGHLEVAKLLIEKGADVKAAANDGETPLHWASWGGHLEVAKLLIEKGADIKAVEINGRTPLHWASNEGHLEVAKLLIEKGADVKAAANDGETPLHWASWGGHLEVAKLLIEKGVDVKAAENDGETPLHLALNRGHLEVAKLLIEKGADVKAVEKGTDFNAVENQGWTPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA33</accession>
    <name>A0ABR1WA33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7735 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667828.1">
        <property type="nucleotide sequence ID" value="XM_066812486.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045546"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056637">
        <property type="entry name" value="DUF7735"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24870">
        <property type="entry name" value="DUF7735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7735" evidence="2">
        <location>
            <begin position="25"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="223" mass="22933" checksum="BA36BB11F4216B3C" modified="2025-10-08" version="1">MLSPTAGTGVLQARAEVTTATEEPMPTSTADPWQCALANVTKYFDVITPTGAFSTALVSYGSVLLAPCVATATGLDELDCTVSNGEDWCGFSTTAPPAMASSYVSYASAAADFWRSNSASISSISSDCPNWWGRPDVNQHVWLSQFITHAGCYIAAHPSTSIDSPSSTQSGFSSVTSSGTERSSTADSTLPGATAAADPEAATSGAASLGSPLLRRVSQVLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAX5</accession>
    <name>A0ABR1WAX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668130.1">
        <property type="nucleotide sequence ID" value="XM_066812788.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045848"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="14045" checksum="3F86CB4A43182287" modified="2025-10-08" version="1">MGPRLILSMLPLSACTTPDTIPYAILRAAPPTKLYSTRRPANARTHAHGPTAQAVGGGQLYGQHDALENEVQVTALDRCGVVRREEQGQGKRIVAEKVGRRPLRPRSRGTTSDGRVQPAQPLLNGSYVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAY1</accession>
    <name>A0ABR1WAY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008468</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668125.1">
        <property type="nucleotide sequence ID" value="XM_066812783.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045843"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01299">
        <property type="entry name" value="Met_dep_hydrolase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057744">
        <property type="entry name" value="OTAase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="79"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="457" mass="48555" checksum="539F5B35CF6180DF" modified="2025-10-08" version="1">MRVSHYTESTECGNGEEESPGTTTATTRFGIRGDLLIPGCGQPIEDGAVVVADAMIEWVGDFSNRPAKYDAVKFHHVKVLMPGLWDCHVHFGGHGLAFSTLNASSSFLPGAPTLAGAVTVADLRRTLDAGFTSVRELMGYAGYLWPGIRDGYLVGPNVYSSLAALSITGGHGDDHELPLCAVKQFGEAGGASYLCDGVDECTKAVRTMVRRGARCIKVCSSGGVLSLNDDPEDRQFSDKELKAIVDETERSGRAVAAHAIGKAGIMAALRAGIKSIEHGCYLDEEVAILSYLVGPMLTLGFTVKEKGATLVATRHIQESLLLDPSGFPEPVVKKIKKIVPLTRKNYDLAIQQGVKIALGTDTWNSNPEHRVAHGKNAMELTYAVKAGMTPLQAIAAMTANAPEVLGRLAPKSGQLKAGYDADLIGVAGNPLDDLAFLTDPNNVTHVWKGGKLYKSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB23</accession>
    <name>A0ABR1WB23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668174.1">
        <property type="nucleotide sequence ID" value="XM_066812832.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045892"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03676">
        <property type="entry name" value="NUDIX_Tnr3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622:SF8">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="147"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="330" mass="36679" checksum="A33B50D7B28E2027" modified="2025-10-08" version="1">MSQPKQRTYLDLVKACDNYPHVDISQRPYSQDDQTALYQLLLPGDSRSHGFMLPSIVQKMPWTSNFVITHDPSGPRSVRVLDPSNGADTANAINAAFKEVIQAASDSKVFGNLIRPHPEDYKVLGANYDGKRVQLLRAAAGLFGICCRGAHMTVYTRTSAGEIKVWVPRRSRHLKTWPGKLDTTVAGGIRAEESPFECIIHEADEEASLPEDFVRKHARSAGVVTYVAESAAGSGGELGLVVPDVLYVYDLEVGSDVVPKPQDDEVEEFYLMSVEEVKEALLREEFKTNCASVMIDFFVRHGILTYDNDPDFLEIVTRLHRSLPVPTRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB27</accession>
    <name>A0ABR1WB27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007488</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667145.1">
        <property type="nucleotide sequence ID" value="XM_066811803.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044863"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052837">
        <property type="entry name" value="Mitoribosomal_bS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_bS21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41237">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN MRP21, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41237:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="48"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26399" checksum="E9C9ACA8947E6C20" modified="2025-10-08" version="1">MRSASSVRATSSTLRLTSSPARASHGKITASLRALSINGCQMRTRRHYADWASPSRPSRPAEEENIVKPTGPSSSTSSSSVDGPAPRPSIPMFRNRNAGRTFDAPDPDFTVPGLGARYARDGSLDATDFSNFKPGDFNKRGSPDELAAMAAKKPVVRCVARTGRTQYVSKGADVGRAFKMLEMQCTSNRVRADFQKQRYHERNGLKRKRLASERWQKRFKGGFKATCKRVSELRRQGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCI6</accession>
    <name>A0ABR1WCI6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FMN-dependent 2-nitropropane dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008044</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667701.1">
        <property type="nucleotide sequence ID" value="XM_066812359.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045419"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF34">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="348" mass="35720" checksum="454B458BB6029A9F" modified="2025-10-08" version="1">MASGNLLHKWFPTAERPLVISAPMFTVANGALAAAVTKAGGLGMVPAGMDPSATSPHLAALDEQLAIAGRILDESDRSSDSTGGDGSLASLPIGVGFLTLLATPEAYRANALPIIRRHRPAFVWLFGSEPAGYGPLIELFREAGAGWGIKVFVQVGTVEAAREVVRQGADVVVAQGSDAGGHQFAAAASVVTLVPEIVDALRGEGEFREGREERGRGGGGGRCGGWEGGCGGVGVGGGWGGDGDSVTGAEHIIRSSVNDAIMGYPTWSNLYAGRTILHSGLEDIANGVSIEQVHGAFKNAMSEGDEKRMITFAGTGVGLANKSQPAGEIVHEVRAEALAVIAKLKANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCX4</accession>
    <name>A0ABR1WCX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar ATP synthase subunit D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668332.1">
        <property type="nucleotide sequence ID" value="XM_066812990.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046050"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="235"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="29705" checksum="3B110EB0FACF7975" modified="2025-10-08" version="1">MSGAGDREAVFPTRQSLGLMKSKLKGAETGHSLLKRKSEALTKYVEPVPMAMQRFREITRRIDEAKRKMGRVMQVAAFSLAEVSYAVGGDIGYQIQESARQARFRLRTKQENVSGVLLPAFESYQTEGNNDFGLTGLGKGGQQVQRCRETYARAVETLVELASLQTAFVILDEVIKVVNRRVNAIEHVIIPRTENTIKYINSELDELDREEFYRLKKVANKKQRDTAAADAELKKKMEAENKENAGSGGGQAADILAENEDDDVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDD3</accession>
    <name>A0ABR1WDD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAM50A/XAP5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668497.1">
        <property type="nucleotide sequence ID" value="XM_066813155.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046215"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048337">
        <property type="entry name" value="FAM50A/XAP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007005">
        <property type="entry name" value="XAP5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722:SF0">
        <property type="entry name" value="PROTEIN FAM50A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722">
        <property type="entry name" value="XAP-5 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04921">
        <property type="entry name" value="XAP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM50A/XAP5 C-terminal" evidence="2">
        <location>
            <begin position="277"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8081022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="466" mass="51240" checksum="313B527F768B9A4A" modified="2025-10-08" version="1">MSRFASRNDQASVAGLELRVRAYFDNGNVFLEGGGGFLECCHVLDDAALEGEHSDVTFTVTTYLTTTTKPLSHTLPHGTSNNADPDSRFQAQNKTTQQRVSDQTVGLVKLSDFRKRRAEVLEQQEREVREAAVAANSGNGSGIDRSQTGTPDPNATNSDGNASNDNSNNEKAKDRQKKLLGNKKRKTGGAKSKLSFGDDDEEEGGDGGESTGKEEKANGGDKTATTTTATKKSKFKANANVSIVPRAVTKSALQREAAERDALRREFLLKQEAVKATEIAIPFVFYDGTNLPGGVARVKKGDFTWIFLDKSRKVGAELGVGEKTNARREWARIGVDDLMLVRGGLIIPHHYEFLYFIMNKTLGPNNQILFDYSAEPPVLSNANAAAEEASAEPMSTADKRAAKVLPDIDTLEGAADDPTFTKVVDRRWYERNKHIYPASTWQDFDPEHDYQSQIRKDPRSGNTFFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDD9</accession>
    <name>A0ABR1WDD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysine acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668001.1">
        <property type="nucleotide sequence ID" value="XM_066812659.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045719"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055100">
        <property type="entry name" value="GNAT_LYC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053013">
        <property type="entry name" value="LAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815">
        <property type="entry name" value="LYSINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22998">
        <property type="entry name" value="GNAT_LYC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYC1 C-terminal" evidence="1">
        <location>
            <begin position="192"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="390" mass="43918" checksum="57860A7A22BEDA0E" modified="2025-10-08" version="1">MGSLPHTGLPDAESSDLILTHPTQDEKYATWQLNSKEWKGALSEEDYLRREPYLETVPLSKDGGMQHWVLTSEATPEGAKRTVLSSCETLRKRVLVGDAAGQIKEGIAYGVGSVFTDPSLRGNRYGARMLRELGKMLRNGVEPLGCQQQRPLASALWSDIGKQFYAKKGWPAYPSLHVTFAIPEGMPAGGTEAARHARPITYDNLKEFCDLDEKLMKEQLAKLRSDGKTRFCFAPDYDIMRWHFYRDDYIARSLFKDRAPAETKGAVAGPDGKRVWVLWVKNFHENPQETAKNKMYILRLGIEDETAPTEELAESFAAVMDKAHEYARGWNLGKIDLWNPTATISSLIEASGLQSEIVERHVDSIPSMTLYGEDEGGHIEWVANEKYCWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDY3</accession>
    <name>A0ABR1WDY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">26S proteasome regulatory subunit RPN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008524</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the proteasome subunit S2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668181.1">
        <property type="nucleotide sequence ID" value="XM_066812839.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045899"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016643">
        <property type="entry name" value="26S_Psome_Rpn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041433">
        <property type="entry name" value="RPN1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040892">
        <property type="entry name" value="RPN1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18051">
        <property type="entry name" value="RPN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17781">
        <property type="entry name" value="RPN1_RPN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015965">
        <property type="entry name" value="26S_Psome_Rpn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RPN1 N-terminal" evidence="6">
        <location>
            <begin position="61"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit RPN1 C-terminal" evidence="7">
        <location>
            <begin position="829"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="886" mass="98537" checksum="5267221B444F5265" modified="2025-10-08" version="1">MAKDDVPKSADKGKGKAVADTKPDETKKGKDAQVNGKKDDEKIVDSSEELSEEDQQLKNELDMLVERLTESDASLYKPAMEAMKTSIKTSTSSMTAVPKPLKFLRPHYESLTKLYEDWPEGNDKASLADVLSVIGMTFSDEDRQDTLKYRLLSPTEDIGSWGHEYTRHLALEIGEVYGKRITAEEPTKDLVDLALVLVPLFLKSNAEADAVDLMSELEIIEDLPKFVDGETYSRVCLYLVSMVNLLTYPDNEQFLRTAHDIYKRYKEYTQAMVIAIRLNDLDLIKADFESAPDPALQKQLAFLIGRQKIWLDVAKKGDESQQQDIEEALCNIKLAEYFKTLGKELNILEPKTTEDIYKSHLESSRVAGMTNLDSARHNLAAAFMMLVEQDKESWVWKTKDEGMMSTVASLGTLLMWDVENGLDKVDNPKSQAGAMLAIGIMNSGVRIDSEPALALLGDQEKLENKSPLVRTASIMGLGMSYAGSQKEDLCELLLPIITDSSQEMQISSMAALALGMVYVGTSNPDISEAIVTLLLDEDRKTQLTDKWTRFLALGLGLLFFGRQEEVEVILETLKAVDHPMARPTALLAEICAWAGTGAVLKIQELLHICNEHMEDSDEKKGDELLQSYAVIGIALIAMGEDVGQEMVLRQFGHLMHYGEPNIRRAVPLAMGLISPSNPQMKVYDTLSRYSHDNDNDVAINAIFAMGLLGAGTNNARLAQLLRQLASYYHRDQESLFMVRIAQGLLHMGKGTMSLNPFHTDRQVLSRVSAAGLLSVLVAMIDAKQFITSQSHYLLYLLVTAMHPRFLVTLDENLKPLTVNVRVGQAVDVVGQAGRPKTITGWQTQSTPVLLAYGERAELEDEEYLSLSSTLEGLVILRKNPDWEDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE47</accession>
    <name>A0ABR1WE47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667924.1">
        <property type="nucleotide sequence ID" value="XM_066812582.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045642"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="314" mass="34568" checksum="6908A1BBDF48C253" modified="2025-10-08" version="1">MDSTTATLSSLSSNPFRPHSRHTANTSVDLMPYIKGVNSSRETFGSAAYRTTSENYSQPSVPALSPLSPKSGFNERTDPRSDFNIDDELSSSDDDDFSTRHPRGSGEEDLIFNPSGYGFDAGELPGLPNPLDFAVSLEKPQPTISLRSSKYSLRGHQAFGATIPDYDCDFFSLPTSPIAGPSADSRVQNSRFQPPKYEHTYSSDDNGHAYGTDDEDTEDEISFDIPRSRGNTPNRQPPQATWWAGSQSDVIEEEEDTHMRVLETAAKLRREAKRLNRMSGATVRRRKESFSSRGTEATRSVHPGASNGSDADIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFH7</accession>
    <name>A0ABR1WFH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008732</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668389.1">
        <property type="nucleotide sequence ID" value="XM_066813047.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046107"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470:SF1">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="27"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="423" mass="46565" checksum="E6E38B343B4A1D5B" modified="2025-10-08" version="1">MRKPRTSPEPTPEEARREMQTLKRMQHRGASEGEVEDWLKQKVFPDTDAIARHGLDMRPKPTFQHCIPNSSNATPYKVSKPIPDLVYGYATDRRRTPFTSAQRIAGSKMEPEMGKIDSHAALAFPFFVIEFKGDGPVNGSLWVATNQCLGGSATCTETVSRLNYLLQQYPGARPVGNMAFSIAMSQNSAELYVSWKTEELEYYTREAAAFYLKRPEDFLDFRRYVKNILDWGKGPRLREIQEAFDIILEEDRKIASAQAKQRPAPSVSSSTSSKRPQVAQAGTPPAAASRASTSRTQSDRHERPAPSGKRPAVLAGYQSPSVPSGSKSYQSGSYAGSGGGSRAGSVAGSGRDRSPNPQSGHMPRRHIHHHHHQQDPVDLLQGPIIITRRSSTCRLATLTAAAATPHFPTLMVDDDNTACCSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLN6</accession>
    <name>A0ABR1WLN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668969.1">
        <property type="nucleotide sequence ID" value="XM_066810046.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043106"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="222" mass="23856" checksum="404BEEAFDB0EAEEB" modified="2025-10-08" version="1">MTPAHSTAGHDLDAAKRHLHLDPIPLRRVPDADLDRAVRRELARRAEVLGPVIDARARVLGLAVEPRQELAPALAVVHLGAHADRGRAQLGDARLGWGFDGLQEVLPLGPVRVDLDRGDAVAALLARREVQRGRGSCRGGLHVEHWVIDQWCDRSKEGITPCTSFATASIILATSARNAASPNVTEHLEHHYNYFMNGMASIGEQLCMLTGSGECAAGKGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLT1</accession>
    <name>A0ABR1WLT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_005751</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668989.1">
        <property type="nucleotide sequence ID" value="XM_066810066.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043126"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF4">
        <property type="entry name" value="SYMPORT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="480"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="519"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="134"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8084480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="637" mass="70408" checksum="12FCA251146E1442" modified="2025-10-08" version="1">MEASTVVHESLNKAALCIGSSIGPSKSTDEMPNYDTLPGDDYDDTVSEGTPSLTDAATEDVQEGVPTPIQYHIVHDFVKQHGLLEYIDLFERSAISLQGDVRVDQIPGITAAELRALELETERKWRQPKTLYFTILVCSIGAIEQGWAQASMNGANLYFPKEFGIDSPDFRDTLLVGLINSAIYLSTALVGAWLSEPLNYRFGRRGAVFTGALMCLFSNVASSLSQSWPQLLLFRVMVGIGLGIGASTVSIFAAECAPPSIRGGLAVSWQMWVAFGVFAGFLANVAFFNFGEMTWRLQLVAPALPVIPLASLVFHCPESPAWLMKKLRYAEAFESLCRLRNTEFQAAREVYAAYTLTRTSSNDPIPKPSIGKQFMELYSIPRIRRATLASFSVMISQQLCGINIISFYSSSIFLDAGFSRFGALLASVLFGLVNFLGAFPAIWTMDTLGRRSLLLLTLPLMALTMFCAGMTFSIPADSLAHFGLLAVLVYVFCALYSPGMGPVPNSYSAEVFPLSHRELGMALAVATTNVWAAVLSLTFPRLETALGTQGAFILYAFLNLVAFVLVYLFVPETRQRGLDELDEVFSVRTRDFARYQVGEYLPWWLRRYVLRQDVEEPKPLHHEVVYRSILQGEGEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMF3</accession>
    <name>A0ABR1WMF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669223.1">
        <property type="nucleotide sequence ID" value="XM_066810300.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043360"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="128" mass="13989" checksum="A326480D651936F2" modified="2025-10-08" version="1">MSDGKPVAIGSMEELNELFKNTTYVVVDFYADWCGPCKQIAPRLELLASRHNLPGFFAVAKVNVDHARDVAASYRISAMPTFMFFKEGRQVAVNGNAYIQGANLPVLEDAVKKLGALAQKKQIEAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNQ5</accession>
    <name>A0ABR1WNQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669673.1">
        <property type="nucleotide sequence ID" value="XM_066810750.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043810"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046853149" evidence="1">
        <location>
            <begin position="22"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="117" mass="12276" checksum="D77B89A92B5BCDE0" modified="2025-10-08" version="1">MRTTQALAALLTVAATVTAQAWPSCDPECKSCGLTCGQNCNAPLVPADCQDCLYCRRESSACSYVQLGGQDPSPHCQTCYGSCQCRIAAVCYDDLPPVTTTSGTAPPASPTKPLIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP12</accession>
    <name>A0ABR1WP12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase C15, pyroglutamyl peptidase I-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006434</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669672.1">
        <property type="nucleotide sequence ID" value="XM_066810749.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043809"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="entry name" value="Peptidase C15, pyroglutamyl peptidase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000816">
        <property type="entry name" value="Peptidase_C15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402:SF1">
        <property type="entry name" value="PYROGLUTAMYL-PEPTIDASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01470">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00706">
        <property type="entry name" value="PYROGLUPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0788">Thiol protease</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047010921" description="Peptidase C15, pyroglutamyl peptidase I-like protein" evidence="7">
        <location>
            <begin position="17"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8085163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="46655" checksum="9459DBEC5201A78E" modified="2025-10-08" version="1">MSTSIALLRITPLVLSTCVLRFSMDQLLFLWVFLNPRLAKHANTVLPSYLDIFTTRKSYILSAFYPALIATGLANRYSTQPSPQASSSAAWWYDGGTLLALLHFAFAARLKGKAQAIIAVTAARKDGGATATAEKMLSWLHLHAFRSVFVDLPCMFCYAIAVMRCLRNAFDLTMATGESTTKVLVTGFGPFLDIAKNPSYEIVCRLPQTLPSGNVTIIAHPEPIPAAYHKIADVVPKLIADHEPDIIVHMGLAVERDYFAVESSALKEGYHEIPDIARRVFTRAENKTRFGKSSASLTTDLPLEEVVDSWKDSVAQARLRLPSSSSSSFPSGAGKAQGSGKKGTKGTKEKQEQRELDVRLSDDVGTYVCGFIYYLSLLEMEKKGKRRNTVFFHVPPLGTEDGVDIGVKVTESLIQALVDAITNKGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP33</accession>
    <name>A0ABR1WP33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyridoxal-dependent decarboxylase conserved domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006571</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669809.1">
        <property type="nucleotide sequence ID" value="XM_066810886.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043946"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050477">
        <property type="entry name" value="GrpII_AminoAcid_Decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735:SF4">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE-DEPENDENT DECARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="988"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1118" mass="124585" checksum="0A8861BD00247050" modified="2025-10-08" version="1">MASKKEALNGIVRPQATPGNTSYNMTATHEDKSHQIISSYFIGPQAENLGYFRDNIRVILNELESARHDYFPGDGKFISEKTQQTKAFIRSQAKLKNAVQKASKIIARASIPFWSPRYQGHMCTDMSMASLLGYFMTTLYNPNNVAIEASPVSTVAEIEVGEQLCNLFGYNTQEDNPEAPTAWGHVTCGARNLKFYPLALRKAFGPNQKLNFLSEEFYVGTCQGERKLFTHMSNWELLNLKPNDILDLPDRLYLEHGVSNKFLSEIMNEFTIQSTGKDELERELGLTKPCQYMLSTTRHYSWPKGAAICGIGSDNVIGIPVDLGARLDLGELEKRLRSNLEAKQPVLAVVAIIGSTEEGAVDRLSGILALRKQFQTEGLSFVVHADAAWGGYFCSMLPRNYEPGDCTNLPTELGAADGFVPDSSLRVETQEDLYAMRFADSITVDPHKAGYIPYPAGGLCYRDGRMRFLVTWTSPYLSRGSVTSIGIYGVEGSKPGAAAMSTWLANKTIGLNPEGYGALLGEVTWTCTRLSAEWASLTTPQSPFTCVPFNMLPSELGEHTSEAKIEAEKTRIRHEIVNKSNHEIVAVDATRPDDGEYSKSMTLMRALGSDLNINAFALNFRREDGSLNKDIEEANYLMSRVVRAFSVESPTDNPTQIPLFLTSTEFSDELYGKCKENFVKRLGLSPSTQDLMVLRNVVMSPFPTDQNFIRKLAQTFYDVVERETEIVRQRNKFAPDIHKFLIQGIEKIYLIHLPMFHEANHRRQLIVSASFDAAAKAKYDILKQANPTEPLILVTTKKILLKDAFNKSGKFQANIMTKASGIILQDVYVSLEAKVVTRPLKSKRRLDKYPDTYMPFYLYGTASEANIDHIIVRAPNTQLSAGRCQLQFYQEVEDESTIWKKDLVLLMENVREEPMQPFPSNSEIGSKNGAIVSHESFHVDAKKLAAKKQATKLNNMSDGVEKALNGGMSNGATNGVSAAPEDASYKEAITRPRGQPKNDQNGNGVEALKHDEDTAPKLHTAAKVVTSETRSASARGSEFFFRPGATFQVSVWKDPSRSAKTFDVKKLVTADNFVGRGTLKLGDSVYVDSEAMNVDRFKKVENISEWRHEFDQIGKELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPC7</accession>
    <name>A0ABR1WPC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">VosA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006647</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669885.1">
        <property type="nucleotide sequence ID" value="XM_066810962.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044022"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF18">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="7">
        <location>
            <begin position="35"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8085376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="311" mass="35084" checksum="ED02308FAFF686D4" modified="2025-10-08" version="1">MDNSQYPAQWAQMPPAPSYPQLGSVMDHQTLPSSPPLYSGYHLEVRQEPERGKVALGKEKDKKPIDPPPIVELVVPTEQDRNRLFLQNPYLILIAFLEQVDNAPSTKPLGKTTPKDSGDRDANRDEESKTIGAYMAGSTVSSLHRLKDTDNRDSGFFIFPDLTVKKEGWYRIRFTLMTMEENRNENRIDTAGFDGSWITICNIHSKPFQVHTARTFPGMAEGVRIRLRKDSRQVTVKKRNHDVARHLKSDVQEEVPYDSLLGDAGSAKRQRTSSTGYSNPSPSPISGGTSYANFPRLSTRLRHHIHSRTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ49</accession>
    <name>A0ABR1WQ49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">VHS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_006936</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670174.1">
        <property type="nucleotide sequence ID" value="XM_066811251.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044311"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14235">
        <property type="entry name" value="GAT_GGA_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16998">
        <property type="entry name" value="VHS_GGA_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052653">
        <property type="entry name" value="ARF-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008153">
        <property type="entry name" value="GAE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041198">
        <property type="entry name" value="GGA_N-GAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18308">
        <property type="entry name" value="GGA_N-GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50180">
        <property type="entry name" value="GAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50909">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="7">
        <location>
            <begin position="34"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="GAT" evidence="9">
        <location>
            <begin position="181"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="GAE" evidence="8">
        <location>
            <begin position="476"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="454"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8085665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="598" mass="64745" checksum="1CEDBCA6FB009731" modified="2025-10-08" version="1">MEAASARAAARDRWNEMGFPGLRNSSASSRAPAIADLINSKKGSAPREAAVAIVGYINHRNTNVALLAINLLDICVKNCGYPFHLQISTKEFLNELVRRFPERPPIRPTRVQTKILEAIEEWRSTICETSRYKEDLGFIRDMHRLLSYKGYAFPEVRRDDAAVLNPSDNLKSAEEMEEEEREAQSAKLQELIRRGNPEDLQEANRLMKIMAGFDTRSKTDYRAKAAEDVGKIQAKARLLEERLAAFKPGDKMTEGDVFEELASALSSAQPKIQKMCEEESDDHEAVAKLLEINDSIHRTVERWKLLKKGDIEGANAIAQGAPIQSLQSSGGQASSSAANELSLIDFDADASGTNGSGNNGESSSQAAGVENDLLGLSLDGGSSFGQGGGISLGFGANSNIPGQPLLSSMTQNSNATGAAADPFAALTSPMFGSKPATPQPSAMAAAPRLRRLAPAASNEDDEWSFSSALPPEAPSLPKDHSAVVKPGEVQIDMKAARSVQSPNALALSFAFSNNTAQPVSELHFQLAVTKGYELQLQPQTGRNLQPSQKYGVTQNMQVWHAGDKSKKVETIKLRWRVSYKLGSETKNEMGDVAEFGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRD0</accession>
    <name>A0ABR1WRD0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nucleolar essential protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005859</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669097.1">
        <property type="nucleotide sequence ID" value="XM_066810174.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043234"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18088">
        <property type="entry name" value="Nep1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005304">
        <property type="entry name" value="Rbsml_bgen_MeTrfase_EMG1/NEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636">
        <property type="entry name" value="NEP1/MRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636:SF5">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03587">
        <property type="entry name" value="EMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="254" mass="27912" checksum="C64A4572114632CF" modified="2025-10-08" version="1">MAQTAGTQSLPPPALPQLVAEQHTPIPLNDKNSQRLIVVLSNASLETYKAAHGGGGGRMGMQRDEKYSLLNSDEHIGVMRKMNRDISDARPDITHQCLLTLLDSPINKAGKLQIYIHTAKGVLIEVSPTVRIPRTFKRFAGLMVQLLHRLSIRSTTSQEKLLRVIQNPITDHLPPDCRKVTLSFDAPLVRVRDWVEGVGSKQSICVFVGAMAKGADTFADQFVDEKISISNFSLSASVACSKFCHAAEDSWDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRF9</accession>
    <name>A0ABR1WRF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dipeptidyl-peptidase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669624.1">
        <property type="nucleotide sequence ID" value="XM_066810701.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043761"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039461">
        <property type="entry name" value="Peptidase_M49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422:SF11">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE III-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03571">
        <property type="entry name" value="Peptidase_M49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="460" mass="51789" checksum="F49761B1ECC2CF45" modified="2025-10-08" version="1">MASPQVYRLEIAHLFNGLSEQEKHYSHHMARCSRFVGRQDHLTTGFPESLPIFDFILALYQSCDGDWSSIVDEGVVTNQDMASFLEYAATFLSNVGNYYGSGDQKFVPRLRMDALEALATRSPRSKVLYAQFKDSIVAIPPFSLGFPGERAQSSYYPGPVAVTKNDAECISRYMDAQHIYPENTRLRKAEDGALEILQASVLLGESELQLGDSLSSPVVKLLKGDHAADLEKVCENLQKANEYAANDTQRRFLAEYIESFRTGNLESYRDSQRTWISDQGPKVENIFGFVEPYRDPYGVRAEFEALVALADPFETKLLTRLVEHSDKFICRLPWAIAENSGKGVFEKTLFEPPDFSSIHSLAYCSSIIVPGINLPNYNDIRQDVGFKNVIIANRMAAESTAATWPFIDSDELPTFRNHKHSAYYWWVVLHELLGHGTGKMMIEQSTGQYNFDPGNPPTNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRS0</accession>
    <name>A0ABR1WRS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669578.1">
        <property type="nucleotide sequence ID" value="XM_066810655.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043715"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1072"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="489"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="789"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="917"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1159"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1174"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1196"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1248"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1272"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1292"/>
            <end position="1304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1316" mass="148003" checksum="8F220C1357A3972A" modified="2025-10-08" version="1">MSQLPDDEEWRALGGDESQESLMYSTQPFSQQMPHQSDWDKPQYVQVEHSQLENNSMDIDSLGKHQMDQQSATTDIANTGASIVGLGNLISRPHLVDPQQEVNNTFTFSQYDPRMPSQQLRSGPETSSATAVAGGDGLSSAQMGAHRISNPQPKDSPLPTRESSTKKSSPEMSRESVRLAPAISRTPTQRTEDVKTRDQQGNSHEHDQTHHYQSPNKISPPEEPHSDNTEGRDDSPHEKGEPQSQGVRPSSDLQRSATEQHERQSESTNTSSSYAIVEKPSRSRERHHHVSTEMPASVSTSEGLKKHSSSDSGDASINNPTPTRPGVKARQPLGGEKCNVGLQIESSGTSRSAHGRSLEPGKHAHKVANPRAERQRPDGPRDLVFEHRRQERPRPRHEPVDQSSRQPSRVHLGRRYPATPAMTRPLRTEPVQNPLCRPTSASSNVSKRRAPQVKTVPAKRSGVEERLNNDFRGLTDHWNSYFNSLGEYRDDVHAELEALQQQVEEQTKEIEGCHDTIQSQAQIIDRTTAERDEWAEQAEQERRRADSSASKMQRLHEKCQEFKNQLNAATEEHQRLYRRNRETILAAQKEQESKSERIRQENDKIRADIQASVIEVSKEAQEQIARLNEETSALRVQLDERQKDLSDEKNIAAGLRKELEQARLLLTQNVQTLTSQNEKIVKTLNELTQDGLHISLSEQTHTLDTILKSIEGVRVSNHGAIADLAQSLKNDFFKEVAGAIQEGMTSNQPITAADKDALTDGIGSIQELCDHIYNQVRDDQHSQNVQYMYQESQSHIQMLEERLQEILEQWEQAESRNFEFGQENEELQAELVLLGEEKKELQLEANTTQALNDENYALMGLIERQQEKISANSDLEEQVGFLEATITSLQSEAEVNQYLEDQVACLEGQIAEKDKMIQKSDKVSKQLEESLEKAVRRSKGTEQRLRDDRLELQERLQSTEKERSRLENDLEVAKEKLQELSSARSSEETEMRNLRDKMDVQNATIEKFTKEVQATQHIQEQLKASLRDWVKDYKDIENMKKLFGQIDWSRMENTASAADLMEERIRRVVVQSPMPMGEEVDEPPPPSVEQERESRRQAVPPKSIMRVTRASAKNEALNEALEDSTGPQPMPEKPLVSNHSMYNRPVQGAPNDSAHDPLSGSQKRARSSSVPSDTGRENDVEYANKRARSGGPAGADSSNGIQPKLSQSMDYTPQDSEHEITEKNMSIQTFEGNLRGGPLQRRTSSLVTYGSKDSTSSSYADSHGISQVSIASSQTLSQGSLGSQLPSGPSRTEGSSQDQSQGQLRTLPFKHRHSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRU3</accession>
    <name>A0ABR1WRU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Indoleamine 2,3-dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006791</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670029.1">
        <property type="nucleotide sequence ID" value="XM_066811106.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044166"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657:SF10">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00876">
        <property type="entry name" value="IDO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="416"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="427"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="53208" checksum="0463798E5EEA7AA1" modified="2025-10-08" version="1">MSPHALSPSLGKTVDETAAYLSTKFAVTSNGFLPKEAPLKELPSYYASWDAIIRRLPQLLRTGALREKAREFEVLSTDELKTEAQWRRAYVILGFLAQAYVWGGCQPAEVLPAAISVPFLRVSAHLELPPVLTYAASNLWNFTCTGSTGDFTNVDAVQSMHTFTGTEDESWFFMISVAMEAQAGRAIPAMTRALEAAAKQKTPRDYAALARALDELTASIEKVGRLLERMHERCDPDVFYHRIRPFLAGSKNMEAAGLPRGVLYPEHQQDDGKWTGAWHQWRGGSNGQSSMIQFFDVVLGVEHTNEGNSRASPPPEGENHPAAPRSYHDEVRDYMPGPHRRFLVHVSQQGSLRALAQKLQQQSGTSSLDEEQRRFCDAYVRATETLGTLRNKHIQIVTRYIVLPAKRAARAMLEKTNGEDDGVQAAPQRQNLATSSAMKSSQDGGGGGAAEEPELRGTGGTTLIPFLKQSRDETFEAGYLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXT1</accession>
    <name>A0ABR1WXT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002919</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670852.1">
        <property type="nucleotide sequence ID" value="XM_066807234.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040294"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01830">
        <property type="entry name" value="XynE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053140">
        <property type="entry name" value="GDSL_Rv0518-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784:SF3">
        <property type="entry name" value="GDSL FAMILY LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784">
        <property type="entry name" value="GDSL-LIKE LIPASE/ACYLHYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046459747" evidence="1">
        <location>
            <begin position="23"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="234"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="452" mass="47968" checksum="4C553D02AA7F3A90" modified="2025-10-08" version="1">MHISRWPTLLLPLLLNSVAALATTDGHANHEEGGKKHWTGIWATMPQLTEPANLPPAPYNANGVVFHNATIRQTIKVALSAQTIRLRLSNAFGGSDLPITVATIALPANKNGATGLSAIDPSTVKTLTFSGGGSSANYTIPMGALAVTDPIEFPVEKGAVITISLYLAEGQTTNLITSHPGSRTTSYFAPGNVVSAADAVSSEAATTKSADHWYFISALEAWLPRPKTSALVIVGDSITDGRGSTKNQNDRWPDQLQARLNAHLPSTTAAIAILNQAAGGNRVLQDGLGPNALSRIDRDVLGQSGVRYVLLFEGVNDIGTAVADPASQQAVGTRLIAAYDQILTRLHAARLPVFGATITPFCGGAPGLQPYSDPERERTRQRVNAWIRDSGRFDAVVDFDALVRNASRPDQLSDEYNSGDYLHLNPAGYKAMGGAVDLALFDKFADGVDRMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXY3</accession>
    <name>A0ABR1WXY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002979</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670912.1">
        <property type="nucleotide sequence ID" value="XM_066807294.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040354"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033370">
        <property type="entry name" value="COG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="683"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="688"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="813" mass="90200" checksum="F7E68AC49D670CBE" modified="2025-10-08" version="1">MATPDTSNLTSSTQVFTTYTLPQIRQIHKSLHAHIDEKAARLRTQVGNSYRELLGTADSIVQMRHDMTRTQNILGEMGGRCGRTVVGGKITGLARFRGLDDAEAEMGCVARVKLLEACGLAVGKLLRGARGAAGGRGERLVLAAKVLVLSRLLVSSFGDMGELNEELRAAVEAAKKNLGSLRRRLLRGVEKVLGRISDGLEQADILKALCAYSLASSSGTRDALRHFLNVRGEAMAFEFDVEEYEKTRGTENVLQGLDLYTRTLLDVQSIVPSKLSDALASLKKNPLLADESLRTLEGLKLDIYEKWCGDEVQYFTPFIRHDDLDGKQAKDMLTAWAKKGGEALLEGMKKILEHMNEFKAIVDLRTNVLQHWIKDGGKARGFDPSVMLDGLRDTINNQLLGVLDVKVSKLRLVGSEVGATLEGWRAGTSDQYNSLWSDEMLDLDMGVGSTQVTHEILSRLHGKNNTVAKAVTGYEIWYRLIDDVNEVVGQLQRQRWDNDVEEIEDEETIEVRQKLLSKDDPDKINKRLNTALEQSFQQLDEELNTLWQKHIGSADSGHIAMYLLRVLRAIRMQLPKLDSTKSFGLESFPSLQEKLAIEVGLAPLEGFSSDALARTRVTGRSLWEGEPALPTLPSPGVFKLLRDLIRSMGDAGLDLWSPSAVNLLKKTFGKQLGDAWRAALESDGAITKTDEPMKAKVPGEEEKSEGEKDEKDEKSDGDESLGDEKEGSEKASGAATKETPSTDQRQDLLIQWLYDIHLLKVYLGTSETPNEELKKLADEVLKKTGLEDGVSERLRKATQEYWRRTSLLFGLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY73</accession>
    <name>A0ABR1WY73_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003042</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670975.1">
        <property type="nucleotide sequence ID" value="XM_066807357.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040417"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF8">
        <property type="entry name" value="S-TRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="7"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="81"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="226" mass="25271" checksum="EC1E6B7032D5F1CA" modified="2025-10-08" version="1">MGSPSTDKIILYTNHTCTWANRADVVLAELGVPFEERIINVDGPRPPEFLKINPRALVPVLIWNDKIIIESAIVCQFLVDGALRRASMSFFTDAYWSKFHTTLFRLFESTTASDEEQVVDEAVQGLVREVEPLLGDAAPFFGKSQRLTLAEVITGPFVIRAVTLSKHGVYPTSLNRLIEDKAPNFHKWAIAVSNHPSITAVFDEQVHVARSRAKRDRMRKAAGLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYA0</accession>
    <name>A0ABR1WYA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003028</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670961.1">
        <property type="nucleotide sequence ID" value="XM_066807343.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040403"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="7">
        <location>
            <begin position="55"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="161" mass="17562" checksum="7530363B9DB7DC78" modified="2025-10-08" version="1">MQHQVAQPSLFQSSGTSPRFGLFILSEPNLINNVGRPEHLSAAWPLASPQLAQELLDLTQQASHYRQLKKGANEVTKTLNRGIAEIVLLAADTSPLAILLHLPLLAEDKNVVYVYVPSKIALGRACGVSRAVIAASITSNEASDLNNQIRTMKDKIERLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYC4</accession>
    <name>A0ABR1WYC4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Proteasome subunit beta type-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671023.1">
        <property type="nucleotide sequence ID" value="XM_066807405.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040465"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03757">
        <property type="entry name" value="proteasome_beta_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="263" mass="28932" checksum="DD25E68495DA7E99" modified="2025-10-08" version="1">MAMFSQNPVLDGPNYSFAEAPQARADGFREHRFNPYTDNGGTTVAVAGDGFAMMAGDTRSTSGYSINTRFAPKVFKIGGSTSSQEDANILLSVVGFAADGEALKERLDAICKMYRYRHGKPMTVNACAKRLSTILYQKRFFPYYVYAILGGLDEENKGAVYSYDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYIPGSGVGHALQERERAPLPRSEVEILVKDAFDSAVERHIEVGDALQVMVITKDGIEEKILPLKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYI7</accession>
    <name>A0ABR1WYI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
            <ecNumber evidence="7">4.2.1.93</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP-dependent NAD(P)HX dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003150</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6S)-NADHX + ATP = ADP + phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19017"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(6S)-NADPHX + ATP = ADP + phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32231"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.93" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671083.1">
        <property type="nucleotide sequence ID" value="XM_066807465.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040525"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592:SF0">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF C-terminal" evidence="9">
        <location>
            <begin position="15"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="185"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="231"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8088189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="345" mass="36803" checksum="BCEC06D38AFEF574" modified="2025-10-08" version="1">MSSDSPEMSTATKEILGKVRQMVPPMLEKFHKGQLGRIAVIGGSEDYTGAPYFSAMASARLGCDMSHVICTPGAGAVIKTYSPNLMVHPLMRQSPSPSSNDCPAPEDTDPEKVSSKIIDMLGRLHVLVIGPGLGRDPLMQETCAKVLAAARKQKMPVVLDADALAVVTSRPELFVGWEEVVLTPNAVEFGRLWKGLKPDGDNGEASDSDKSPTAKVEALSRALGGVTIVQKGGQDMISNGKHTMVVDLQGGLKRSGGQGDTLTGSIATFLGWRQAYLDGIWDHGNKLESKELLGLAAFGGCAITRLCSRNAFQKKGRSLQASDLTDEVHPSFLELFGEDEPDAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZB8</accession>
    <name>A0ABR1WZB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671407.1">
        <property type="nucleotide sequence ID" value="XM_066807789.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040849"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="370" mass="41688" checksum="7D4148014DB3214D" modified="2025-10-08" version="1">MASLQQAIRDTATRTSELWIQIAQTDYAPSALGQQKRRVVELSEALDNVTAQIKSLDQDRGTALMCHQRYRDSIVRRLAYRAAWKHNEYQAKAASVAAEYYEVLQQEYRAKEKKCALERQCEDAVALLESLEHVASQHHEAQAELDRLWERIFSRCTSKYQHQRALQQKVASAQETHRQAQERCEESGTIVEALAGSLTRVAAAFEEVKKALVQGQMSGDGAETSFLQKAQSHVDSAQCLLRQAKCDQESLEAIEDLRIASRSQKGCQWDGPYSTIIWRDRIRISRKELEMCHAVLKRNLGVAKTQHEEAELEVEVCAEALRTSKECLRMARAAIYLEIAGNEALSMARLEDISRGSSPIVAAPPPYLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZH8</accession>
    <name>A0ABR1WZH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003478</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671411.1">
        <property type="nucleotide sequence ID" value="XM_066807793.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040853"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="282" mass="31676" checksum="FF3A7502020BFAF0" modified="2025-10-08" version="1">MAVHVTHQNPSFRLPPEWYYLLTPQTSLRVCHLETHQARQQTLYIDLEVEPFTFKMSGGLHVSSKKHEAALCMMRVRPLDWLRHGPIDVRDLQLINANPAPFVSYGHTSYVRKLYYRKAGDEKFYESNWTVENNQKCMDIVARMGGNVVGFESGAADGAVNDLTFTLVNVNITTPRGYGVGWGFLSTRAENVRIFRGPLDTCSIHPWDAMILRDCTANTDNMIAKEEISSRKWDILAMKMCEDYDAPWLVVAIRDSGAASDAHNPGLPDCACACGGPPTDQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0Z0</accession>
    <name>A0ABR1X0Z0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004039</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671972.1">
        <property type="nucleotide sequence ID" value="XM_066808354.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041414"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039136">
        <property type="entry name" value="NUFIP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019496">
        <property type="entry name" value="NUFIP1_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309:SF0">
        <property type="entry name" value="FMR1-INTERACTING PROTEIN NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309">
        <property type="entry name" value="NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10453">
        <property type="entry name" value="NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="424"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="424"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="227"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="348"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="500"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="353"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="567" mass="61972" checksum="FF176661181F23E9" modified="2025-10-08" version="1">MAGQYSYPPPPPPPPPAAAPSGGYPSYGQSPSYSHAPRGGGSVVMGANRGRGGHHGPPYGGYSHQEFAGHGPAQYGGQTPSGYWNSPAQPNHSPHTNAPLPPSTYHPNYAPQGYNAPPPSNYPPTAYPRTRNLHTRRPTVPTPRTMLLGSGVNPAQLIPPTLTEADAEVSRVTEVVIGQSMVRGRLSEWGLTRTPAMPLKRAMVTPRTILHLSTMHLRPTRRLLTLPIPLNRGRGRDGSGAFRGRSHHNDRGGDKFRHRGQRPHHDHSPAQKSDPSSSKKKKRKTNTLGLTPGDGEESEEEAVDEEKRLSELLGADTPVVDDMASWVAERRANFPTKARVEAKKAAEAAQRAEVGEDQKPVTKLDKDQEKAEKLRRQLAKVERKLEKRKREANDEGGRNENDKPESLTTRKAPSFLPPPPITRADPTNHCKYYSTGGICGKKGKCRFVHDNLVREQALREQAANGGRMTLKQRLLRNDKDQEDLAIVRSIMDLRTAGRLATGQQATNQSSSSSQRPVHPLPQKVVDAASLPPAPDVLPDGRVKSAYISTEARDMMNELKPYAGHSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X158</accession>
    <name>A0ABR1X158_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672047.1">
        <property type="nucleotide sequence ID" value="XM_066808429.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041489"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13053" checksum="538B31E9793E12A0" modified="2025-10-08" version="1">MTRRTRVANIGEQRRAEQSRAEQVWPKAEEGKRASPCRLGQVWKTIADPGRSWIAVVQTTLQTAVRREHVGETWCTKHEREQDADLGLAAEAQDVPAVVVLIRRRTSKASGKHSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2I7</accession>
    <name>A0ABR1X2I7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dihydrodipicolinate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672534.1">
        <property type="nucleotide sequence ID" value="XM_066808916.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041976"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF47">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="330" mass="35439" checksum="C0A2C0B99231A304" modified="2025-10-08" version="1">MSSSSRASEPKAKPLPAGVWTPVITLYDDTAAQGVDHGAMYRHCQHLVRSGMHGLVYLGTNGELALLARDERQAILRTARRAVADLGRPDYPLVAGISAQGTAESVQLAREAADAGAGWGLLLPPSYWAKALPTEALLAYFRDVADASPIPIVVYNFPGVTSGVDLDSDQLAALAAHPNIAATKLTCGNVGKLTRLTSQFGPEHFGVYGGSSDYLLPALHAGGRGCVTGLGNVFPRATSMIYDLWAAGKLDEARELQDKVANAEWACKKGIAQTKYGAWWFVGRKSLGLENEALFRMRKPYLLLGDEAKRWTVETMRVLEATEDALLGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2T7</accession>
    <name>A0ABR1X2T7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NAD-dependent histone deacetylase SIR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004656</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672589.1">
        <property type="nucleotide sequence ID" value="XM_066808971.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042031"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47651:SF17">
        <property type="entry name" value="DEACETYLASE SIRTUIN-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47651">
        <property type="entry name" value="NAD-DEPENDENT HISTONE DEACETYLASE HST4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="6">
        <location>
            <begin position="99"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="428"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="506"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="523"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="556"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="583"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="597"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="610"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="645" mass="70024" checksum="78FCAB42BC47FFE9" modified="2025-10-08" version="1">MDSSSSDLSEPPSSDPPSSPLSELSKSPSLSPIPRAAIARYLSPISTAPSGSTSPMKNSSDADSICVNPDGPPPPKRRKVERKPRTTEHLNLKAGYTDNQQDEELIDRLKSSLRKKKKIVVIAGAGISVSAGIPDFRSSDGLFKTLRKDQKLKGSGQQLFDASVYKHDDSTSSFHDMVRELAQKTKTARPTPFHHMLATLAEEGRLLRLYSQNVDGIDTAMKPLATQIPLPEKGPWPKTVQLHGGLEQMICSKCNSTSPFDGSLFHGPEPPPCKNCEEMDTIRTSYAGKRSHGIGKLRPRMVLYNEYNPDEEAIANVVKADTRARPDAVIVVGTSMKIPGVRQIVRNMCKVTRERKDGIAVWINLDPEPTGAELRDCWDIVVRGKCDDVANLVGLPHWDESYGDDVKVDDQKYEKSIRSSQLEVRIPSPSLSASETVKSESRAVTPVEAKPKSIEKVQGIPTPTASPKMRNALPTGKPAARSKQSQILFPGAKTAASGDAKPAVKGAKKPAPRKPRQPKKAAQKAAVPAATVKTSFKATKAAAAVPSSKLPVKRSAGSDKAKDSRPHDARTEFTLRPTTTRQKRVDYEYDSKKAQDAVNSQLHQETNAHQSPPTTPTQSSRPGSAHSEVTISPPSKPRGMANLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X370</accession>
    <name>A0ABR1X370_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672757.1">
        <property type="nucleotide sequence ID" value="XM_066809139.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042199"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18647">
        <property type="entry name" value="Fungal_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="409" mass="45607" checksum="EE6D67B916498798" modified="2025-10-08" version="1">MCDPSSSGTYPDDKQPDLLFFKPDTRKSLWRFPLKKKRSANGDDTVIVDVDGTVDGEVVGEWDTSVPPTQEQREAIRATLPPLPKKDLDANGVDRAVYRSSLWNSANPAAEALHALDARAPAAPGCPGDPYPYLPNVGWFLPDYFGRIFHPNEAGHNAIASFALSRAIDLRAEVLGLDPQVCTVTDEFKCWQKEGRRGYASSDRLNENYKKYCEGVKAPGGGQTAWKNSGPFHEGTPDEHEFVVETTEHASEFNKDECLESMERIINSCDGNDPENPMNWKFGGTWKRGEYRYSVNIKRDNRPWPPIKKTYGSCDGSYHFVYSDYTIYGAGWSGSDYGQDTLLPKAKGCLGEGVTKWKFDYFDKPDDKGMEWKSTFRTPIFVNNRCFKNNKVAFGAGGFTDGCGGSGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X406</accession>
    <name>A0ABR1X406_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Mitochondrial DNA polymerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_005102</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673035.1">
        <property type="nucleotide sequence ID" value="XM_066809417.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042477"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08641">
        <property type="entry name" value="DNA_pol_gammaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002297">
        <property type="entry name" value="DNA-dir_DNA_pol_A_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041336">
        <property type="entry name" value="DNApol_Exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047580">
        <property type="entry name" value="POLG_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267:SF0">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18136">
        <property type="entry name" value="DNApol_Exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00867">
        <property type="entry name" value="DNAPOLG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family A palm" evidence="15">
        <location>
            <begin position="726"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1102"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1154"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="506"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="1104"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1159"/>
            <end position="1168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8090141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1187" mass="132755" checksum="6BB993D15AA27C9C" modified="2025-10-08" version="1">MLNPARSHVRGASATASFVRLARHRAQCHRPRQSQLVSRPILQRWQSTAAATAQRPSNDAHDQIQPATLAIPSKARFNEIDVQHLSEHIYDQVFTEGSKPPPEELQPPIAFDLPPLQGKTLDEHFHKLGVDSAEPFLTHAKQFAQENVPTPPRNWVHQSGWTKYYSNGETEKVEFPDETMLCFDTEVLWKESAFAVMACAASPTAWYAWLSPWLLGESESDKHLIPLGDPTKERIIVGHNIGYDRARILEEYDLKQSRNSFLDTMSLHVAVNGMCSQQRPTWMKHKKNRELREKIANGTDSVEVARFVANGDYGDEEEELWVERSSVNSLRDVAHFHLDVTLDKAIRDEFSVLDRNGVVAKLDDLLTYCAADVKVTHRVYKVVFPNFLETCPHPVSFAALRHLATVMLPVDQSWDAYLHNAETTYKKLSDAIQDRLIGLTEKALEIKDDAEQWGNDPWLKQLDWSGQEIRMVKGKKKNDPPRPDSRQKNAWHAQVAGEATAGEATAEATAEEAAAAQKAAEEKAAEEKAAKEKAAIKDAIALTVRTRVAPLLLRLAWDGYPLVWSDKYGWTFRVPTSDAEKYSTTQLVRCDMSDESVEALQEDREAIYIKLPHKDGPNSRCTNPLAKSYLVYFDNGTLSSEYAYAKEALEMNASCSYWISARDRIMSQMVVYEDEKPPVPEMGSSDGGHNRPGYILPQVIPMGTITRRAVENTWLTASNAKKNRVGSELKAMVRAPPGYCFVGADVDSEELWIASVIGDAIFKLHGGNAIGFMTLEGTKAAGTDLHSRTAGILGITRNAAKVFNYGRIYGAGLKFAGTLLRQFNPSLSEQETLDITSKLYAETKGTKTNRKPLSKRPFWRGGTESFVFNKLEEFAEQERPRTPVLGAGITEALMGRYINKGGYLTSRINWAIQSSGVDYLHLLVVSMDYLTRRFNIDARLSITVHDEIRYLVKNEDKYRAAMALQVANLWTRAMFAQQVGINDLPQSCAYFSAVDIDNVLRKEVDMDCITPSHSTPIPHGESIDIMQLLAKGPEAFLDPAIVPARNAPNLDGIEYTPRIPVMETLNKQAVDLKYFLRAQITSDDAELREILREQREEYKAAVSGIGGTGSSSSGGGLVGGSGTDQPRKRGPRKLVPCSSQTKMMPHFYQPFETPKFSKQKYQGSTNAQWGDWEPMPPKTSPSKSSWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4S5</accession>
    <name>A0ABR1X4S5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673302.1">
        <property type="nucleotide sequence ID" value="XM_066809684.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042744"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36151">
        <property type="entry name" value="BLR2777 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36151:SF3">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic" evidence="1">
        <location>
            <begin position="46"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="286" mass="32916" checksum="3D89C0D2A4DD4E9A" modified="2025-10-08" version="1">MTKDSLTLLFCQSRWRLPTKNPRSPSFTQKSYLHPDFVPHHLNKISQESIILGGGAAAILLQVANPSVGAGVHEHSNFAHRVPDRLRSTMTYIYCMSFGTPREKQQLADLITRVHADVRGTLTEGPDRGKEYTALDPHLQLWVAATLYATAVDVYQRVFPHGIADDAEHERIYAEYAVLACALQVPPGLWPQTRADFWAYWDRQAPWYLRLFLPAVRVVTAEWLPPRLRAEYGCKRHRTVYKFMEKTVRAIYPALPTRFRTWPVRFYLSDMRKRMAKNHAVVGKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X803</accession>
    <name>A0ABR1X803_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_001899</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673510.1">
        <property type="nucleotide sequence ID" value="XM_066806214.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039274"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051654">
        <property type="entry name" value="Meroterpenoid_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897:SF1">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="5">
        <location>
            <begin position="97"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8091538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="286" mass="32173" checksum="87354AEAB55AC291" modified="2025-10-08" version="1">MADSKESYDMEAFKAKIYRAEFPDDIGSIRQLLEEYSGIPPQDVTAHIHTIRDRMWAVKPYNCIGSFRFLTLDFVANRHYQSALSRLRAPGSTATFLDMACCVGQVLRHLAWSGVDPTRLYGADLERPFVEAGYDLFRDREGAFGRGATLVAEGGGGDPALEVLDGKIDIVHASAFFHLFTWRDQVVAAKRVVRFLRDKGESEDGEEAIVFGRQVASTSPREITGPRGERRFLHDAATWQRLWDEVGEATGTRWRTEVEMVDEGRGEAGALDDANKKRMNFACFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8B3</accession>
    <name>A0ABR1X8B3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH-ubiquinone oxidoreductase 40 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673630.1">
        <property type="nucleotide sequence ID" value="XM_066806334.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039394"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="51"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="375" mass="42651" checksum="C0508E5CE546C6DD" modified="2025-10-08" version="1">MASFATAARSTQRLVLNASQRRAISDVAITRTGKPILRTQGGRHSLGGHTVTVFGATGQLGRYIVNRLARQGCQVVIPYREEMAKRHLKVTGDLGRVHFLEYDLRNTDSIEASVRHSDIVYNLIGRNYPTKNFSLEDVHVEGTERICEALAKYDVDRYVHVSSYNADPNSPSEFFRTKGLGEQVARSIFPETTIVRPAPVFGFEDNLLIKLANPSVQFTSNNMQERYRPVHSIDVGKALELMLYDDSTAGQTYELFGPQEYSTAEIAEMVDREIFKKRTHVNVPKAVLKPVAAILNKVLWWPMLSAEDIDREFIDQTVDEHAKTFKDLNIEPSDISNFTYHYLQGFRSSSFYDLPPATEKEKREDRKYIHVTDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X932</accession>
    <name>A0ABR1X932_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002296</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673907.1">
        <property type="nucleotide sequence ID" value="XM_066806611.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039671"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815:SF1">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="54"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="39338" checksum="18E8FBA027010057" modified="2025-10-08" version="1">MATETLTPSSSPHRFQQHVGFDNITSNEPPTKDNPISLTLNYRHNGYQKTRSSRTFMVGVDDNSYSDHALQWLLDELVDDGDEIVCVRVIETQVRSSDKSYHDAASQLQKHIQSKNVKNLAIALVVEYAVGKLHNTFQSFIKIHEPSMLIVGTKGRSLDSVQGFFSSYNSFSKYCLQYSPVPVVVVRPNEKREKKKAKRAQDPGPTTTALTNSNPPSTPTKKPIVSRWRSGCLPHSIRRSNLLTSTQYWLGGGKRAATPTREPASMLDLAERGQEPLAPVNKEGDPVPDPSPDSDGEDSEYEEVFDVTSGADEAEKKERLHKMESNEGAALKTSGRKMSTESIDDEDEGGAKTGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9A0</accession>
    <name>A0ABR1X9A0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase/reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002384</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673995.1">
        <property type="nucleotide sequence ID" value="XM_066806699.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039759"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8092023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="278" mass="29791" checksum="CFCA50BB817ACAD4" modified="2025-10-08" version="1">MSASIQKSVLITGCSDGGIGSALAETFLERGYHVFATLRNLSKVSSRLSAEAAKPKGNNNVTILQLDVLSPDSMAAAVASVKAATGDRGLDILVNNSGQAQILPALDTDIDEARKLFDLNFWAPLAMVQAFTPLLIEARGCLVNNASVSAYVPMPFSGTYGASKAALVLASNTWQRELAPLGIRTMTLITCGVKTKAFDSVEAPQLPTSSYYHAIRDYLAQLTDGRLQNDAMDAHRYARDVVRAVERGALGEVWVGQNAFASRMAWLLLPWSIIVSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA91</accession>
    <name>A0ABR1XA91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674368.1">
        <property type="nucleotide sequence ID" value="XM_066804595.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037655"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="584"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="642"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="541"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="407"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="432"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="727" mass="79602" checksum="73967EB860C80678" modified="2025-10-08" version="1">MMLAHQHYTPSRTNHLHNHHHNQSSFTFDDSTQYTNNFPTTTSNATSLPLSTTPFVGGLPARGNYNINKLNKVPSLTSESIESAANSNTNSLNQVPDLMPSEPSWLLQGQQQTPRAAHRLGHQRESSLSSLGSNGPASPFNANISNPQIAVTDSTSDGYHDLTAGGDGNYSYQLGKQPMTLNDSFYTALQQSFGNTHHDTTILADGLPNMSGSQPQQTNTRLLPAPDFSPIGSSTRSNARSVASSGSTVGGDSPATPSYHEPEDSNTQRRRKNGETSSESSIPLQYFLDELDLNPTSHFFGHEDNSCLQDFSNDIAYGNNPNMPKLDRTMTDIYSDELYSPSFTITSASPAAQSQLAMSPTNDLFAQRLQAANSQHLSATQSPTSSSSHSPFRHGSPLAPSLNDFAQPQHQQQNQQQQQKAQQVRISSAQQQREKVKQEQDAKALQQHLARNALNQQQGTPNTISPKDAMLEFNDSDDSNFPLFPPQETNNFHMEQMTKPAPQQSHAFSTAPETALQSAFNFSMPTSIQIPQQYPFISRPNQQQATPSVSTFSRMSSADSNGSDMTNMSTPQRPAKTTADGGTYTCTYHGCTLRFETPALLQKHKREGHRQANALHTARAVSAAVSSPGVPDTLLGSQAGPHRCDRINPSTGKPCATVFSRPYDLTRHEDTIHNARKQKVRCNLCTEEKTFSRADALTRHYRVCHPDVEFPGSTAVAEDPPCEWASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAL5</accession>
    <name>A0ABR1XAL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_000384</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674472.1">
        <property type="nucleotide sequence ID" value="XM_066804699.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037759"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF2">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6 13" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 14 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Chitin-binding type-1" evidence="16">
        <location>
            <begin position="132"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="17">
        <location>
            <begin position="194"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1406"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1425"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="176"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8093699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1793" mass="198968" checksum="AD1A1EDE5A66F10A" modified="2025-10-08" version="1" fragment="single">VITARPGSTDVLPELPNACRAVVSPFDYSAKARRDHGLPVCSADSHLHARHGDEIVPASPEAGMSLIGQTEFSSLFGRQVVGGDDYTCGPDRPCQNKACCPKKTGQCNYGEEACGTSGTSPNEVCWSNCDAKAECGKNAKVPDQKCLLNVCCGKWGFCGMTEDFCDKEDHGATGGCQSNCNQPGPKNKASDQLNRVIGYYEAWRHNSTCQDMGLDDIPVNSLTHLYFSFAFITPNEYNIIGMDGLPDKLFTDFTSLKKKSPGLKTIIAIGGWTHNDPGPLQKVFSNMVSSKETPGTNLMSFLRQHAFDGVDFDWEYPGADDRGGVPEDGENFTRFLKELEDENKKQPKKYIVSFTAPTSFWYLRHFDLKAVDHVDFVNVMSYDLHGVWDRENPIGSHIYGHTNLTEMSLAFDLFWRNDVPANKLNMGLGFYGRAFQLADPSCNKPGCLFKGGATKGACSGESGILSYREIKEVIDTKKLKPVHDKSAGVKYITWNSDQWVSFDDKDTFKQKKNLASKLGLGGYLIWAIDQDDAQLSALSAVLDPKPLGDFKTSDKPDENWTGTNEMCYITGCDAHCKAGEIKITDQKCGKNKKSELCCPLSGAPDPKECHWRGGDTKFCNGHCEDDEVMTHMSKYGGGKDCWDGQLAHCCKSALGEKNICKWRGVGEKCHSDELPLTFSGTVLEILEDVAKVILRVVGRAVPLVSLTGEVLLQVLDSLDLDTKKLYCCPKDEVKKWKNCAWYGKPGNCFDGHCPDMKTVQITDSYFGGSETCGIHADRVRTFCCESDGEPLFLPVPLKNLFEHPPEGGVDTDFTLETDKTSAGGDTDPNEAAFQFVVLVSLRSCRSPSTSATAPTGTSLTAMMPSRKANTRSVWSALTLLPTATAARLVLVTVSLALSCRCPRVVAQASTPLPRAWCPPPEDDHAKLLPRHLSNLAHLKPVVYDLTFDYEFERVPRDLGSTQMRIDFSNQDDYWDTVVAGSVSKKRDLSLDNNDRSNAGLARRSLADVGGNHVRWLEEEFRDDYHLSKIDKRALHERWFGKSVLEWLAQLIKPEIKREFMHRYDDTVTAKLVDDSWDCTRGDVRYDGHVLAQALLNVRVESSFGFTLIVNDLSKTPLSMDQSYLTFYNKGEVTGVITLEAVARVSYEKKSIPGIATIGPQLTVEGSIDAALAMAGTVETKLEIAKWEVRQVLPAENGYNPELINDSKADLKRTGDFDGIKKPEFYAGVAVQGDVTAKLSAAAEFGLRFVDRWKVPPATAAVVGEASIMTKLKGGGSTSGTCPFTFGMDVGARLFARVSGFGWTSGDYNLTPDWNKNIIEEGTCPNLGPIPLKRDLRLIEDGNYSVVSAAYGGHILPSMYENPDFISENPNQRRSILAKRSGVYGPVISIPVGKFFCPPLADGNGGDGAADCKSVDPPWGVPDLSENDRRGLDTSDLEGRYFHGNLDSHQRHAQDSDHPHNDSHHHYSNEKYELLPELLKRKIEPRADKKISICGSSQNFKYPSSGEIPNANVYGYEDPDNCNSFAWGNPLAGRVTGTKYDTEHLLEAQMINEFFNYLNGELGQTLPDPQAPAQNIRFCDYVQKLFAVQVVASIDSAQGGNAQASPIEHIAAQFPTYTWHAEEYIALQGNINGRIKGKAWGDLTKRRQPARLDLRRSRGERGFYKIMRLCLGSRMYHNDLEPLEILRKQKRRIGDILDLLDTTVLPANPPAGHAAWQPMQLRSKWDDFMKYRFLLMQRRTMKVIDDFFGTMRDFWVTDAQRQAHANNADVIQLIDDIEAMDVFMRNMGPWQFPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAQ3</accession>
    <name>A0ABR1XAQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="7">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000420</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674508.1">
        <property type="nucleotide sequence ID" value="XM_066804735.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037795"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF152">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="36"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="258"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8093735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="490" mass="56101" checksum="FDA4B738B026F945" modified="2025-10-08" version="1">MPPLERSNSYVIRDLEFTLRSQFNKTEFRPQQRDIIQAALDGKDVFVQAATSFGKSLCFQLPAVIDQGITIVISPLLSLMMNQVEALRAADINARSLNSNTPIPERDEIYKDLKSGHPRIRLLYVTPELCAQDRFRDRLKVVHEQKELARIAIDEAHCISEWGHDFRKDFKLLKWFRESFADVPIMCLTATANVAVRKDVLSTLGLNKDTNRLRSFTMTAHRPNLHLEVRYTQDQDDQRLDDFIRWIRSVYKRREADQRKQELEVTGERIDNVPGIIYTISRDECESLAASLRAEGLGAQPFHAKLTKDMKEKTLANWVSNVPGYDIIVATTAFGMGIDKMNVRFVCHWRLPKSFEGYYQEAGRAGRDGNAAYCFLYYSREDRDRVSSMIMRDRNQAMGGGGGGAAATANFGARAHSLRALAEYCESVDTCRHRLICKYFGETEVPECDYACDFHKDATDLRRRFYMGLASEEFVSTQRGEGAYEVDWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAV4</accession>
    <name>A0ABR1XAV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U6 snRNA-associated Sm-like protein LSm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674553.1">
        <property type="nucleotide sequence ID" value="XM_066804780.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037840"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF8">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="20681" checksum="A9BF1DAB8AE41A47" modified="2025-10-08" version="1">MENLTIHDPSPQQGAPMSQTLGRAPPPQQPQQLPPQMFTTAAQLLDLTDKKLLICLRDGRKLTGILRSWDQFGTFGFCAAAAAAAAPLVSAATTHICASAGRHRGFPVKGYYADKSHGIFLVRGENVLLLGEIDLDKDDDTPAGYEMADFKAVERMAKEKKATDKSREKNKLKKLSTLGFEGENLGEILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBQ8</accession>
    <name>A0ABR1XBQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000831</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674919.1">
        <property type="nucleotide sequence ID" value="XM_066805146.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038206"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF131">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="798" mass="90051" checksum="F59A49E5DAFA327A" modified="2025-10-08" version="1">MADHATPTPTPTSTHDPGTGHGAAPSRSVKRPRPVKSCIECRKRKLKCDRLLPCSQCQKSQRHCRYAPDGDAANLSDASDAEVSERASKKNCVPSAAHEQTPRTRERLLPASSQHAVLEDYGARLDRLETIVLANAESSTNSTPNLRHQPLTASSMTIRGLTVKGGLRTRFFGQNSTRVLLNLFDEAKEFMFSRNKPREVMEAFSDIQKIHRTLQDEQRKALTPITVFVDSMTPIQKRMADILPKKALCDQFLQVYLMASESIYRVLHIPSFMAIYNRWWEGNVQSESFLPQLLSILCIGYRFFGLGKGLQPDRDGVHIPTACSLVRGWLDGLRGKQLVDFGTLQAEVLLLLAQRMINPKNQETWTHLGLIVRMAMTMGLHRDASEFPLKISPYWAEQRRKLWYTILELDVQMSTQCNLPVCVRDGDFTCRPPRNLNDDEVYLEMQELPESRPIDHMTDSQIQVYASSTIRYRFKVVDLINRIDSLTDYQQVIETGTALERALDDIRTVAPQTLPATPEERNKQWAIRTVLDMHCRRALLNLYRPFALSTPDVPQQILAAYLRSSVAFLTYLDDLDPSSESYTQLWHSHNLVFRQDILQAALSVCYYIRHIIAANNGKYGSHARSSAAATLHPGVWNPTRTQPETIEEACLIASESSIALALPRLIRVVENAFNSQTRRIREIGTDLKDLVTLTVVLSVCRGGTVNEVQKRALDGLQVIIDTGLQSMQTSHEAIASLPRGIWTVLQTPLSLVAIQTPPGYVNPVQPFVMSDELPNVIPDDFAMWDMEFWQPLLQNGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCL2</accession>
    <name>A0ABR1XCL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome segregation atpase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675164.1">
        <property type="nucleotide sequence ID" value="XM_066805391.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038451"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="464"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1222"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1707"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1585"/>
            <end position="1689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="468"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1222"/>
            <end position="1234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1768" mass="195219" checksum="AD99E4BF70AABF67" modified="2025-10-08" version="1">MPPVERDAPADRVDRPQHLRHQSSASSATSDQMRGALIPMWDSSDPERAPPPLPLNPQSPTVGVGTSRIGTSAAIQSAHAALNEKARENALVPTMQKRVPLSDMSPEKALVPRGSPHKRMQSLQAPTVRDLSLMIEGSARRDSVSSLAQRAHSPEKNSRPGTPVRGRESERAGSIDREQRDSTPTPMPITLTPVMRQQMKRAPHSILSENTPPQSATMLALQNMPTVSLKDTQPRELPRESQREPWRESHREKEFPMPEPLAPITNHSAAMGKTAPSMDNLSHQMVTLTGIATALQKEMATLSRRSRDNATDLMSLKEATHARDEDIRKSLREIVSAKKAEQRSARETYGDTLYVEHRGHGSPPPSKNGGFSLPRIPSPNSFAASMDGSTLSMNSSAPSLVGDSPATLALLEKIIREMGTKDGQDGIVGRLTELVEMLPGMASSVKVEELIQQLKSTSQELSLVPAAGQGGGGGGNMGRPRNFSFDEDDDGSLRELDWSQQHGSMGQRANALLHDREHQSPAAAHGHEVLNEEVIKVIRGVKDSVAAGGGLTAEVKALVRELRGEVLGMGRDIGRRLDEVSTKTTGKEEPATKVQMERIVDEGIEQVKLHVNELLKEHRRVSSASMKSMVDYQEIYNALNAALNDQEANKAQPDLCRDDVIHAIKEAWEDYKPEISVEQIGLDRDEILVCLREGLEDFAPQRDTPDGATREDVYEAIAEGLKNYSPPKVETPAGLSRDEILEAVRECLEEFEFPVAPSAMNDLTKDDMLDAVKQGLNSFEFPNNANALVPHGAQIDNNEVIERLHDIMQSMREEFKAISEEAKQNIAANGRDTEQVIDATKDGIEQLRVHMEEYIDRASSENSQAAHMDSLLHSLDGFRGEVAELIARSEEGSKSVLTEEIGSLRDAVNSVLVPHTPPMADNREILEAMRDGLERVRQELLRPHAGTAEVLDAMHEGFGDLRASVERMSNKPVDLTANDEILDALKSGLDGVKQDIILLREEQQNPNDRAIATVGDTSSNAMVPISADALKQDDIKNLEVMLTQLRTQMEALEPAAPTESLSKQDLAEMENMIRNVQESVVGITEKQAPESLSKDDLAQMEEMLRKVQESVAGIEYLRKKDPENPDDPGIPVNMEDAANKEDVLAIETILRNTKDRIEDLVDGEQAVRKDHIDNIETLVLETKESVVSITGQLELISKKEDIAAVELLVTQLTTGLDKMKERAEKVSRRPRESNQDGCQRHRSRLLRRQNHYRADVKTVLDTQVEANAKAFEERQAEIVGVGERVTEVKTFLEEFQGLLKGKLEDEGNGLEALQKLLAALSETIESSTVAADLKEMHELMKAEFEESKNGVAGAKLDSDEKLQATSDTLSTKIDEKVGELITKYEAFELVMDGRSKAGEARDVELEAAVVGTKAIADELKLLIDTLGSTVTDSMEKMEEASKTVFGRVDDLFSKSEENHSEDKNEHSMTRDQVQAAVTAVEGLQGQVVEYQPKILESIKDVLLIVGQHYEHAQLTSTDLQKQIEDVKEKENQLLLMPPPEKYDDTEVHSKLDKLVDYSQLDTLDKVHAQVVQTASDISSFLEAQTKRIEADHEDHEKHLQETEKKVQETNINLAVAQAEKEHVEANVSSLRSEEEQLRESIMSLRTEQELLQRQKTRLTADVSSLETAMHIRREELQAMEARAEGLERRILEGVLDHSRALLLTKAGTKGRDAMSRKRVPGARSGLAPVDPASLNAQAPSAHRKAVNIAVNGNRGLIPPTLPGQRGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD45</accession>
    <name>A0ABR1XD45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitochondrial DNA replication protein YHM2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001168</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675256.1">
        <property type="nucleotide sequence ID" value="XM_066805483.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038543"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053017">
        <property type="entry name" value="Mito_Cit/Oxoglu_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982">
        <property type="entry name" value="CITRATE/OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982:SF1">
        <property type="entry name" value="CITRATE_OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="114"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="215"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="316" mass="33963" checksum="1963DEB74F0DC60F" modified="2025-10-08" version="1">MSAAASAMSPSSEKKIEKKPVKFSNLLLGAGLNMFEVTTLGQPLEVVKTTMASHRGDSFGQALGRVWGRGGVFGFYQGLIPWAWIEASTKGAVLLFVASEAEYYARAAGANDFGSGILGGITGGVAQAYATMGFCTCMKTVEITQHKMAAAGVKPTSTFTTFANIYRKEGIRGINKGVNAVAIRQMTNWGSRFGLSRLAEQGIRRVTGKEHGEKLSAIEKITASALGGGLSAWNQPIEVIRVEMQSKKEDPNRPKKMTVGNTFQYIYKNDGIKGLYRGVAPRIGLGVWQTVCMVAMGDMAKTYVEKLTGDKVTAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD90</accession>
    <name>A0ABR1XD90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675404.1">
        <property type="nucleotide sequence ID" value="XM_066805631.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038691"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053060">
        <property type="entry name" value="Cytokinesis_Signaling_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36419">
        <property type="entry name" value="ARRESTIN FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36419:SF1">
        <property type="entry name" value="RHO1 GEF LOCALIZING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="1">
        <location>
            <begin position="189"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="405" mass="45085" checksum="BA7AD87F551BD583" modified="2025-10-08" version="1">MTDRIPAFVRVSGPPNSSFLVGYPGISATLPRIEGKVEIRPAAGYSAPVAISLVRICLQRRETIHPAAENVAKRHLGTPRRDTTDVVGKELLLFRCASGKEAENVIAMDLPFVLFIPFGRGGEETNRRIPPASLQLPNRVLETYYELVVTVQQGQSIQNKYAFPVPLQRYDTLSTFGMYNRPETKIATVDNVVTLGISLPRWSYGPMDPITVYIKLAPNLDWMAKARKVTVQKLTLAIEEEITFNPEGDEPQKKVNRLQKHVQAVGTKLPEAGYVTNMGLIFPHKDLRDSQGIIRRGQPAFPNYEVPSFTTTSTLYKIEFFLTIKAHLTSARDITLRQPIVICPMDHQACKEEMDAIEQAAKEASFVDQNNPMLPAPTIILANDHNALRTLGLCMVGGQKKPLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDH0</accession>
    <name>A0ABR1XDH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675454.1">
        <property type="nucleotide sequence ID" value="XM_066805681.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038741"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052228">
        <property type="entry name" value="Sec_Metab_Biosynth_Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534">
        <property type="entry name" value="YALI0E05731P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="215"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="293" mass="31627" checksum="1C927239464B0AA5" modified="2025-10-08" version="1">MVKLSEVQTLNAALAADSPKPLVAVFLGGTSGIGHMTARALASSVQQAGAGGAAHLSRGPQRAARGGDRRVAARAVSGGASTEGLDETMAILYYSRMRAIQQLTPLLLKSTLPATVVSVFAAGFEDEKKLCREDLSLRDLQRYGYLQVRSHLCYMHSMCMSQLAELHHAEKQLRLIHIFPGLVLTAAFHNPAYPAWFRGERMLFLASPVLYPAAAGDDSSRRGTENEKGGTVRGMDGRPGSGAYSLDWKGDDTHNQKVYAKLGDEGIEALKAQVWEHTNKAFEVIASGEPFTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE22</accession>
    <name>A0ABR1XE22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001533</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675621.1">
        <property type="nucleotide sequence ID" value="XM_066805848.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038908"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="238" mass="27344" checksum="64567F1460A87C4E" modified="2025-10-08" version="1">MVDQPFRNSLYILILWTLVEPFIKNGLFADKKLTTRPKLNFSCLETPVHGTPFPWSVQYKDHFHPGKSCHEAVRISKTVTKGVCTPQNLPKRTLRNLESKRDFIALTENEVLQLRHEARTLSLAVDAVIDTCRGPAGNMLRLHRFATWDCSEADGMSLAAQQNLLRGAGPEDRTIRNREMLMKLLKPAECDASSWPVDTWYDAYPQGIEPLDLLAKRHRKCFEEEPEFQEKEITHSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEJ6</accession>
    <name>A0ABR1XEJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675787.1">
        <property type="nucleotide sequence ID" value="XM_066806014.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039074"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF13">
        <property type="entry name" value="ALDO_KETO REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="31"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8095014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="287" mass="31693" checksum="E631F04CE528CF81" modified="2025-10-08" version="1">MAKRTITDTLRLSSSHPIPQLGFGVYKSPPELCIQSCLTALRAGYRHIDTAQYYANEAEVGEAIRQAAPQVSRADVFLTTKILSPEASAEENYAKCVESVKKLDAGSEGKDGYVDLFLIHSPNCGGAENRKMLWQALERLHQEGKAKSIGVSNFGIQHIEELKAFAQVWPPHVNQIELHPWSQQTEIVAYCEKHNIAIEAYCPLVRNTKAADPTLAKVAEKHGVTPNQVLVRYCLERGWIPLPKSDNEGRIRNNADVYGFALDEGDMEKLNGLNQGAEGAIVQAVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT91</accession>
    <name>A0ABR1UT91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660729.1">
        <property type="nucleotide sequence ID" value="XM_066818541.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051601"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="204" mass="21350" checksum="46E821A56DC0354F" modified="2025-10-08" version="1">MVFIRPYQESDFEACAHIYTHLSPATCHMLVDDDEDNAQDDPSSLSGAVGSSGGGGGGKVVGYCIGCPDPNPAALVRLAYDPRKLLQLDGGDDDTHQGLPLPSQGWRATMHIDLLPAYQRRGWGRRLVDAYVRSVRASGADYGRGAWIGIAPDNAGVVAFYEKVGLRLVVAPPPSSSATGEGESGGGGGGDEEGIHMVLDIAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTJ9</accession>
    <name>A0ABR1UTJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/Exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660863.1">
        <property type="nucleotide sequence ID" value="XM_066818675.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051735"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF300">
        <property type="entry name" value="TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="107"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="30459" checksum="71665CC12C82FC9A" modified="2025-10-08" version="1">MTASDGASTSQQSDPVEVEQDLANGPTHYSLSRALLARKDEYVRRHRIRVKVGSWNVAACPGTDKDLAGWFVDGRGLDKSITKLDLHDQGGKGAEERDVSETSGSSQTGEDDSVRLVGGAEIGLYVLGLQEIIALNSISQYADTSATSKWQAALEAAMPPYYKLITSQQLSGLLLLMYASPEVADTITNVSTVSVGTGLLGYMGNKGGVSSRIMLGETTRMVFTNCHLASGHDQTNLDRRCWDYGRIMAQTQFAPLNHGGILEDEGEKLGDEDFGFGLATSTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTP1</accession>
    <name>A0ABR1UTP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660861.1">
        <property type="nucleotide sequence ID" value="XM_066818673.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051733"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="376" mass="41752" checksum="144FD15BEB0DAF94" modified="2025-10-08" version="1">MIHLEVLALATLGTLVFRFQINGTLKRCWKALHRPSNATLLLHIILSVAEVVRYYGRRYHGEYYLPYSSSNNNKLAAARDIYNTSTASLWTYSQDAYNLDVIRQHEAIRLPTANLLDLILMLIQCHTSLVLARDRVWAGHKSMLRPVYHSQTLFRILFTASSFLLSSPSLFTNITPTTTAASHFPSSILLPLLNLLSLLLNKLPTSATWRSPAQLYRASAMVNASFVYPRLLVWALCRLGGVGPLGRRYRDVYTFAIFLSAVVAMHDGGVALGPQLYIAGVGLFVVLERWVARQVLERTAGGVGVGEEGPETKKGEEGKEKLREGVLPADDGAVWVVKRGLGGSVKKGFAFKDRLVDGLSWYGFVDIDMLRGGKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU08</accession>
    <name>A0ABR1UU08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660781.1">
        <property type="nucleotide sequence ID" value="XM_066818593.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051653"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="99" mass="10515" checksum="31584B6710126D28" modified="2025-10-08" version="1">MHCGGEAVGVDATLKGGSKSSREALRLCVVTILASAQLFWVTRQLGVSGENLVKELESGSVTALPVSVEEGNSAAPRRRPRGLERRWARGSSSRAPQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVI3</accession>
    <name>A0ABR1UVI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_015024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661526.1">
        <property type="nucleotide sequence ID" value="XM_066819338.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052398"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="266" mass="29278" checksum="249470282729F028" modified="2025-10-08" version="1">MADNLRAEDGLDKLWGTSSAKGDVKAFPSDLDARTLSTKDVIRVWYGTTVPKYTQGKLTYDSDKLIAISALAEAIHVNCKDEYLAGLWRKCIISGLLWARRGPGAKATVYRCPPWSWASQNSSVDYIIPVCESDDDGDGDSAYDCEVLAAEVETGKHNAFGNVKSGYVRLKIAILSAWALRIPMTKTQPWYGEFECSLLLWDDTRPTSIPAIMDDDNWMAGRVVCALIGNKRLLVLQPVHPGSSKYRRVGIALKSLGETATANNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVN6</accession>
    <name>A0ABR1UVN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_015062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661564.1">
        <property type="nucleotide sequence ID" value="XM_066819376.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052436"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="121" mass="14189" checksum="18C67F9C11160FA8" modified="2025-10-08" version="1">MGPSPSLSDMAIAYRLVHHGGAPKSWSGRVQDNLHKVWWDNRVSNHFTYSDGRWRAHDEVRQLGREVLLLEGQETDSDKMRLGLLVFFRELLGAVDEDGDEHKYLWDMDEKMDLRRRSDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXG6</accession>
    <name>A0ABR1UXG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661334.1">
        <property type="nucleotide sequence ID" value="XM_066819146.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052206"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="27478" checksum="65470900EAB220E5" modified="2025-10-08" version="1">MMRTRASSSNSCRRSDRAPAYEGNALHWRNISADIPEEENCSVFVTGLPSNIGYFDLLQRVRYGHIVQSHINPPTGNHYGAAAKIVFWDRAGAGRFMAAVRHREVAFLGCRVRATWNRVRVAPQDPADLTSSRVVRVQGPREIVNEQAICVFLWSHFYFDLEEIVTIEQGQEGSILEIRFGSFWFQSENAFRFLRENHPDRQSMMVEWAHDPATLPMPRSEILVNRCQRFLQGQAVGKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1L1</accession>
    <name>A0ABR1V1L1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661825.1">
        <property type="nucleotide sequence ID" value="XM_066816133.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049193"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="133" mass="15130" checksum="E68E83DB08734ED3" modified="2025-10-08" version="1">MPKDSKRPVGAAASQEQGRCGHRAPNLSNASEWVLRSVVRKVIKRDDEVWYRQYRVLFEETVLVRASAGLLLKRWRWHIFNDRCLYPGELVAVKTLDSDAGTPMSIVVSAPKGLQDRNIFVVAPAGDWLKEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3R5</accession>
    <name>A0ABR1V3R5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetoacetate ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012576</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662582.1">
        <property type="nucleotide sequence ID" value="XM_066816890.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049950"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005914">
        <property type="entry name" value="Acac_CoA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01217">
        <property type="entry name" value="ac_ac_CoA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921:SF1">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="113"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="636" mass="69909" checksum="A518B368E92A46E3" modified="2025-10-08" version="1">MTVDHLAPAELWRHPDPESTHMFRFLHHVKFKYQLDISDYPGLLRWSVDNIADFWAEVWHFCGIKASRQYDDVLPRDASMFPRPDFFACSLLNFAENILFPANVDETAPACFTVTENDDEAVTTTWAELREAVRQCSNSLRACGVQPRDVVAGFVSNHVQAIVAMLGAATIGAVWTGISPDNGVSAVLDRLAQIEPKVLFADNGMTYNGKPWSSVDKTLQIVEDLKTKGLKTVVVIKNINVDLGLDDLKAQGVAAESFETFLNSSSSAPLEFEQLPPSHPLYVLYSSGTTGLPKAIIHTALGTLIQHKKEHYLHCTMDHTSRMLYYTTTSWMMWHWSVSALASGTSLVLYTGSPFKPHGYLSIPKLLEKYEVTHFGTSAAYLTTLETNGIYPSMSVDLSKLQAIYSTASPPTSAFPSNINLGSITGGTDIISLFGAPCPLLPVYVGEIQCAGLGMAIAVADSVTGKPTPGEDGELGDAKYQSSYFERFPGVWHHGDFVRIDTRTGGLTMLGRSDGVLKPSGVRFGSAEIYNVLTRFFAGDVEDAVCVGRRRESDRDETVCLFIVMCEGKTFGDDLRQKIKAVIKSELSPPSRPWCRGGMIEVAVKQILSGINIKTNASVANPEALEWFKQWEATHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3R9</accession>
    <name>A0ABR1V3R9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662586.1">
        <property type="nucleotide sequence ID" value="XM_066816894.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049954"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="719" mass="79001" checksum="4F041FC6AE520205" modified="2025-10-08" version="1">MGCQSICSTSIRPTTHLTHPTLTPSHPIAPALHRPSSVVVLSLPASPTPVIILDSILSFLPYMSPEKGRSHEPEQSGYQSDTPATVRRRKSNKTLRSAIDTIDDRTLPSPSSPRTPSEHAISSSVPTLRFPRPIGNRQLTNWVSSSSPDIMRNRSHQDEAPLDSSISDLGFEVIGNDGEIQSSSSEDHYDSRVLEIPEDVQSLADMTDTTGTDAETNEVDSDSSEDDEEEYHGHSSHDSEGLTLVDSHVDDMVNMADQSLEHPTELFTSTDLQKSRSSSVSGDEPLEAPTRKVRNEEKATSAADICKEQPHKAGSDRPVYTTAVGCLTELKKILNRWSKVAMEAFHRTTTRQILTHLLIVLIASAVIPVISVIKPSQSRTSVISTVPAASVSSLRPKMEEPAVPAPTVAPASTPANTLNALQTTNSLGSIVPVPFTRESDAIEDSGSAVALCSAEIHSRDTILIKVPQHVMSSWPAKQTVLVAVSRGSHDLDPESTSLSVVDDGYILQVPQEEAYGVLDVSIATTRKPKINETFQVNFGSNLLGDAFDAGKQLVRGLLRRWWIQSTIQRHGSKKRACQYSTRDAGLAVIGAPARISAKVIQQAKQALAKDKVSERLFQVETEVVRQAHDLRDELKLGLLHAQLNTKLWWLSVQGKVEEHQEYKTAAQSYYHKNVDKAIEARRVRAEKTVEEIRTRQKKNQKKGSKEGRRSFWELGERGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3S2</accession>
    <name>A0ABR1V3S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662589.1">
        <property type="nucleotide sequence ID" value="XM_066816897.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049957"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF13">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1996" evidence="1">
        <location>
            <begin position="4"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="1">
        <location>
            <begin position="122"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="335" mass="37160" checksum="A82830B3AA116ACC" modified="2025-10-08" version="1">MVPSAHVHQIVGGNSFNASMDPAKDMPGESTCTTCSFAEDFSNYWTAVLYFKARNGTYKRVPQSSQIQGAKGGITVYYMQDALYDQQQKSKVTAFKPVSLVHPLSSPCLPFLPITISHYSNTHMKTPNQGFRMFTGNVAARTKAEMAQFRQLTYTCMDNQGTREPETLDFPTRPCRAGIMVNARFPTCWDGVNLDSPDHMAHMAYPANGTFESGGPCPESHPVRMPQVLFEVVWDTRQFNNKADWPADGSQPFVWSFGDGTGFGNHADYVFGWKDDALQRLMDAACVVNCPTAHAKTQSTAAMNKCAKEKTVTEDIDGCKSIVILRFSPLFLLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V473</accession>
    <name>A0ABR1V473_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxy-cis-cis-muconate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662736.1">
        <property type="nucleotide sequence ID" value="XM_066817044.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050104"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF4">
        <property type="entry name" value="CYCLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="361" mass="40490" checksum="F91779B0435D7A83" modified="2025-10-08" version="1">MPIHHLMVGTWTPPGAIFTIAFDDDKLTCELVKRTDIPHDEPISWMAFDHRKKNIYGAAMKKWSSFAVKSPTEIVHEASHPMLHDPQAASAETNTRAIFLLAAKKPPYAVYCNPFYKHAGHGSVFATTPSGALAENLQNYEYQPDTGIHGMAFDPTETWLYSADLKANKLWVHRKDGDGQLTLAGSVDAPAPGDHPRWVAMHPTGQYLYALMEAGNRLCEYVIDPHSHMPVYTHHAYPLIPPGIPNHGTMYRSDVCTLTRSGRYLFATSRANSFDLQGYIAAFRLRDCGSIEEQLCLNPTPTSGGHSNAVSPCDWSDEWLAITDDQEGWLEIYRWKDEFLGRVARVRVPEPGFGMNAIWYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V482</accession>
    <name>A0ABR1V482_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">DNA replication ATP-dependent helicase/nuclease</fullName>
            <ecNumber evidence="22">3.1.-.-</ecNumber>
            <ecNumber evidence="22">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="29" type="ORF">PG997_012725</name>
    </gene>
    <organism evidence="29 30">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="29 30" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="29 30">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="22">Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="22">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="22">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 22">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="29">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="22"/>
    <dbReference type="EC" id="3.6.4.12" evidence="22"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662731.1">
        <property type="nucleotide sequence ID" value="XM_066817039.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050099"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22318">
        <property type="entry name" value="DNA2_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022765">
        <property type="entry name" value="Dna2/Cas4_DUF83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048459">
        <property type="entry name" value="DNA2_Rift"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014808">
        <property type="entry name" value="DNA_replication_fac_Dna2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF433">
        <property type="entry name" value="DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01930">
        <property type="entry name" value="Cas_Cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08696">
        <property type="entry name" value="Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21123">
        <property type="entry name" value="Dna2_Rift"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 22" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="22" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 22" id="KW-0227">DNA damage</keyword>
    <keyword evidence="18 22" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 22" id="KW-0235">DNA replication</keyword>
    <keyword evidence="16 22" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="12 22 29" id="KW-0347">Helicase</keyword>
    <keyword evidence="11 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14 22" id="KW-0408">Iron</keyword>
    <keyword evidence="15 22" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 22" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="20 22" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 22" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19 22" id="KW-0539">Nucleus</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Dna2 N-terminal" evidence="25">
        <location>
            <begin position="529"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="DUF83" evidence="24">
        <location>
            <begin position="740"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2 rift barrel" evidence="28">
        <location>
            <begin position="902"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="26">
        <location>
            <begin position="1096"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="27">
        <location>
            <begin position="1240"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="291"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="23">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU367041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF08696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF21123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="KAK8065978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1588" mass="175491" checksum="7C9A74C78D816623" modified="2025-10-08" version="1">MPLQKSLSEQNRSYRSRQQWQRSKSHASANPAHLPPKRPLAPVSDITKNKLHAFDYRPQVPVPGDENAFFAAPKPKAQEPTNDSSAQHATPTPSSKLAWQDLVGATEAKDEDEDASPTERILWDTTQDPSATSLSPMLPRKKGKKRARSSSPVSSPAAKSKPNTPAMDVKKLCEALKSPHPDPALELWDRFSMTNSSAATPLGAAHPALANMMVSSSPRPPKFLAGANPPPSEGGLRRAISCGAHWPKRRRAERGEYRPSCISTVAEGSPSGGSKSSMVNILLENMTGELNKSSASQLHQDPSRSPSPKKKRQCPEAGAASPPRSSSQSPAASRHQDAEIELPQAATSELSETFGETSSDYGDDDFDDVLMGLDVTMAPTGSNCLEVAMPPPDTGPTSENVPAVLEQTFLDDDDGDDFGDVDDDVFAAAENLVVQAEGAKAQPPLSAGEVQDVGEDAFGDDFGVDFDFEAAEIAATQSAKQSNVSGSFTPVVLKPKAIQRYLVTNVLDHEYTTELGRSCPEKILLVQVDRSKDTKTVHLRGDWVDTAVSPESFIHIIGNFEASGRCIIDINQNILILHPDQLISATVVADSFTCMRRAVLQDRVKATSEASAPLVYGTLLHEIFQEAMMANQWSGPFLNKLIVNISERHVEDLYKIRVSMSDAREHLRSKMPELSSWAAAFVSGQPKVDAVVQGRNGDKALMCVSKLLDVEEHVWSPMYGLKGNIDATVQVTMRDGPQKRTLTVPFEVKTGHRATSNHQAQTSLYNLLLSDRYDIEIAYGILYYMESSQTTRIPAIRHELRHMIMQRNQLACYIRERSVQLPPMKRSSNACGNCYAKVPCFIYHKLADDGDAETSAMKDKFDAVVKHLTPTHQEFFLRWEDLLTKEEKESQKLRRELWTMLSSEREKVGRCFANVMIEEGSALEEKDSPKINRYKYTFIKDTPAPGFSFMDSQLAVGEPIVVSDEQGHFALALGYVTSVRKQKISVAVDRRLHNARIRRAGFNETNNQTFASIMEVVPEGATPTQSQGMFKTPPIRYRLDKDEFSNGMATVRNNLVQVMSDGVFGSREIRRLVVDLAPPTFKSVTSQYAITGPDSLNVDQRKAIEKVMSAKDYALVLGMPGTGKTTTIAHIIRALVRQGKSVLLTSYTHSAVDNILLKLKSDKTDILRLGAPAKVHPEVRDFAILAGQPMKTFEEIHSAWHDTPIVATTCLGAGPDVCLGWRSQSAPPLVQNEQARLGGLDISLFKLLSETHPDSVVNLEHQYRMCQDVMTLSNTLIYNGRLKCGTEELRHVKLHVPDMDALRHRHYDADTIARPGTPKSFCANWRNTSCWLRSMIDPEARVRFINTDDLPSSREEAKGNRTVNPAEAQIVTQLVEALLTAGVPASDIGVMTHYRSQLSLLKHHLRRHGSSIELHTADRFQGRDKEVVVLSLVRSNESCNIGDLLKDWRRINVAFTRAKTKLLVVGSRSTLRGSGDSEMVSRFVRLMEERDWVYDLPADALDSHYWPDESATQATAATGVAATQKSLVGLSPRKRTNQHKTIYEEGQENNIMMRRAAKKGRVTDKALLKGKPILQDIFSEIVSSGGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4A4</accession>
    <name>A0ABR1V4A4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SNF-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011898</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661905.1">
        <property type="nucleotide sequence ID" value="XM_066816213.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049273"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="37152" checksum="699EF6FCFCF35A38" modified="2025-10-08" version="1">MGLLQSVKKAGNWLLPPPSKSSDDGRDQWPSRAAFLLAAMGGCAGQGNLLRYPSVVYNNYGLQWFIPYLLAVFVIAIPALILEISVGQAYRGGTVVAFHNVHRRLKGVGLGPVFVSFIVVQYFTVNLAWIMNYFRNSFTSPLPWEGRLNDFYNNDVVANPDPIAGSLSPDGSSVLAFTQYPNTKLIGETVAWSIFIWFLIWVSIFRGVGLTGRVVYFTMGLPICTTIILVGRALSLDNAREGVKLLWATWRSDQLADGTVWQTAVGQVFFSTGIGFGYFTSYASYNAKHSNAVMDALLICGSNVLFENFAAFAVFGVVGFLRRWPQEGSGSARSWSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4C8</accession>
    <name>A0ABR1V4C8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662779.1">
        <property type="nucleotide sequence ID" value="XM_066817087.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050147"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="462" mass="50953" checksum="BB285BB3272EECA9" modified="2025-10-08" version="1">MAPVVTNPPESIADGWQDIDDATTDDAFSFVSLSISEDSEDEDDGACKSKTLSPSPRRAAVTKDPTKSSPTVPTWTSDEESDGEEEGLERLGDAGNAGNNNMKSAKLPESAWSSTASINRILDADWNPPYLLKVTTSLGKLIGEIMGAISFHGNFAPLQGTKELRGECGKVRDALKTLEPIVQGYSKHWDTHQTSDLPLDPGLYEWMSNLRIELLGLQRLLQHHTGEAHSASDADEASLGISRYQSSLIESNAAISGFLPILQADYDEFHAANLHVAPANGSPVARQYETHWGPGNDASVSRLRCELYDLKDEIDSCQSEFSALIQRQDIPVQQEPLQHFIKSYALIKASLGTMLSNHASEWLDYSMAGGITYHEFCQLNPDTIRSLILQLRDVRNSLDSEVSRVKSARYMNDPDSLLDDIQMEIKESDVEALAVLQEVLFSLLRIQPPSQEQAPPERELEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4W5</accession>
    <name>A0ABR1V4W5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012986</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662992.1">
        <property type="nucleotide sequence ID" value="XM_066817300.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050360"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF53">
        <property type="entry name" value="ALPHA-GLUCOSIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="484"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="59"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="557" mass="61450" checksum="49719E59911A1E93" modified="2025-10-08" version="1" fragment="single">TYVSKHKMANLEKGQLGGSDHAEYVPDTLLIEAAIANSDKETQLPRKELFSRYWPGAVYSVLLSMALIMEGMDVGLVNNFFGHQGYLDKFGWPDANGKQHIPTSWQSAIGNGNNIGSIIGLMLNGWLQSRYGSRRVYMGAMALMGATIFALFFAVNVQMLFAANILCGVPWGIFQTLTTAYAAEICPAAMRGYLTAWVSMCWGCGSFLAAGVLRASLDLDGDLGWKLPYALQWFWVVPLFFAALAAPESPWYLVRRGRIADAEKSLRRLARKGLYTEQSMKETLALMMHTNEMEKIESAQASFKDCFRGTNLRRTGIVCMAWVIQILNGQSIASFATIFLRSAGMPQVQAFNYSMGIQSVNIFATAIAIALMGRIGRRVFYLYGSTGIGLLMLIIGILGFVPDQTNTAIAVAVVMIMVNFTFKISIGPTCYTIVGEASASRVRAQTIVLGRAVYVVGQIAVNQLNPRMLNDSSDAWNWGAKTGLFYFGLCGVWAVWIFFFLPETKNRTFGELDYLFQKRTPARKFATAPVDLFELTGGKPHVTDAKLGESAVEIVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5S2</accession>
    <name>A0ABR1V5S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_013300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663306.1">
        <property type="nucleotide sequence ID" value="XM_066817614.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050674"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16485">
        <property type="entry name" value="mRING-H2-C3H2C2D_RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="64"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8066553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="119" mass="13478" checksum="E4885B006B26D035" modified="2025-10-08" version="1">MADVDMTDAPTTSVAKKAKSGDADAKGEGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGICNHAFHFHCISRWLKARQVCPLDNRDWEFQKYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V645</accession>
    <name>A0ABR1V645_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663426.1">
        <property type="nucleotide sequence ID" value="XM_066817734.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050794"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539413" evidence="1">
        <location>
            <begin position="23"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="244" mass="26117" checksum="D7C0C809F6E79EAA" modified="2025-10-08" version="1">MVSSIYYTAFLLFSCIIENVIALIATPTTVQSEVSDGACERQCTLIANWFGAVDGWWDLASQSDFPANEAVAGPASVHVTATIITVINTISNTTSLETKMPIDWIPSPTNAAGTQVRVVTDSLERTTTMAFPTSFGHFGDSYTKFEWCGNSTTSSVVTFTPPQFRLGNEFDFSNATYGNAANLSDPRGLLANPAYAAGPGLWLMGLMPSLFPPLPTESCDTFFGGPVWGGFLTAWATVTSTAYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V743</accession>
    <name>A0ABR1V743_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013762</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663768.1">
        <property type="nucleotide sequence ID" value="XM_066818076.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051136"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01298">
        <property type="entry name" value="ATZ_TRZ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050287">
        <property type="entry name" value="MTA/SAH_deaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794:SF11">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794">
        <property type="entry name" value="AMINOHYDROLASE SSNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="61"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="51484" checksum="2B18DA75D75DE654" modified="2025-10-08" version="1">MSDSLGITLLRDVTIITVDARRRIILNGFILTQEGRITHVSSKPPNQIPEGTRILSLPGRIVIPGLINSHAHLAQSLLRGLAEDLPLHSWLCDRIWPLEAAYSGEGDAADGYVAVRLTIAEMLLSGTTCFLEAMLTHGSGFANVARAVSEMGIRACLGKLVKFVETNPALELADARDKDLGHMSIPSLLAAHTEFHGTCNGRIHVWAACSTPRGAPLSSFAEVGKACKQHDIGITMHCAEAPRDLPIFREVYGKTPMQFCHEAELAGPKTVLAHMCHLDLDVDLPILKESQTTVAHNPTSNLKLASGIAKVPQMLEEGVNVALGTDGAPCNNSYDMLREMHLASILHKGGLMDAGSIGAHEALEMATICGAKALGLEAEIGSLEVGKKADLVALDVRASWAAPWNPEMFAHGGMDPVSLVVGSCTGRDVTHVMVDGRILVEDGRLLVADEATIIQSARQAVVGIQERSGVRDGRKAGWEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V800</accession>
    <name>A0ABR1V800_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Linoleate diol synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014076</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664082.1">
        <property type="nucleotide sequence ID" value="XM_066818390.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051450"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF13">
        <property type="entry name" value="LINOLEATE 10R-LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="556"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1341"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="352"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="579"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1384" mass="155052" checksum="7E39BB3BAE393756" modified="2025-10-08" version="1">MNGHTSRAPANPQEEDLMQLTLQLRNKNAEATYASFHGDELIGDPAPPQTSTWQDVKAALQPKNWPSLGRIAEGAINGTGLDGQGAATVVGSLSNYSPRRQDFINQGVKDKYDKMLHPPLTYLGDAFQYRTADGKFNSAINPHLGQAGAPYAKTVPSKTASLGAPPDPSDLFEKLMARQEDGRVSESGLSSMLIYHATIIIHDIFRTNDNDKNISDSSSYLDLSPLYGYTQEMVGKIRDDKYKLGLLKPDTFAEDRLLRQPPGVCIMLVMYNRYHNYAARQLLRINENGRFSIPAMYEKTKLVSLIQEHLLDRNEYGQKAPLDASVRELCDQYEKVFAEAQAARPPDASVALAEQMNETDEEREEREATEKTEKDALDAIATFEGSAVYKRLVELTEKLELLLEEKKLKLKEGGAGPGSKYEEFEAQCQGFEDAWEASRKKQDDDLFNTARLITCGMYIQVSVHDYLRALMGFHQFDTNFTLDPRADFDQKKTSRGLGNQVTVEFNLLYRFHCAISRKDEKYTEEFMKTAMGFRDPSKASLPEFLGTMAAIQQKGARDQKRGKGAPKPWEVTFGIPDTPKSTTPTSAAVKNGNGGIPMTGVNGAGETTHSKHFRRNAITNLFDDSQMLEELTSAMDDPISNFGPRNVPRCLKAVEIMGIQQARKWETGTLNDFRDFFGLPRHTTFESVTKNAEIQNALRDLYEHPDKIELYPGIFCESDERMGLDPGPVESSSALWSAIFSDAITLVRSDRFYTVDWNTNSLTSWGMKEVTPNNEVCKSSVFHRLLQRAFPGWFETDTIRFFHPFYTAKQNSIYAKAQGYANDFVETAAPPEASDTDKRNGNNVPAAAPVKKPVKPWYLDSFDDISLPNLPAAVRAVLDPNQKAPSLSSDKLDQYIEESEEDLKRYLEGVMKMIVMRESISMTNSTFQIDATRDFAIPVVTHYVADFLGFGDKLRRHPADKKGSTYSENEIYQHITNCQVFLTYNADETKWMARRRAFKASMQTLIDLTQNGTIWEANHRMHELGVFVAKQVLEYEKDQRKAAAILLLICLDFAYNSVIAFTATLEGYMEDLYKFADSPPPTDGSKPEWVKLQQFVFSTGGKDDKELEKMVQSMAQAKVRLPIVRKAIKTADYQFSRAKAGKPITIEKGDIVVLNLTNAIAQAQSDEATTQSGAAEVEFLTSQLSIADKYGVFSPRRFAMLSLTSMIRFAAQMRNLRRGHDAQGRLKRVPLDPTSEGYAHFMAPARAAWIQQQVRALEDGGGGDAIWTDDVLQPRADTFLTPTWDEFVPFPMTWKIRFDGFGRSDYGVVGGHPFGRVTTAPAVPDFCPPWYQPQGPSTVGARSRLWSASAPRPRPGARRMARMGESALLPLLRTRLGEDDGGQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V851</accession>
    <name>A0ABR1V851_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664142.1">
        <property type="nucleotide sequence ID" value="XM_066818450.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051510"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="114" mass="12935" checksum="D59EEC17423BA3BF" modified="2025-10-08" version="1">MQMQPEPSHGKPPTQRPAEDNTESPPQPRPIRRESGNTSMSQAEQMISDVEDLYEFGVKLSIFPQDVLLLRSLRKMKERFRSLVQPDYPRGPRSATEDDMGEDDSSQDSDSEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V866</accession>
    <name>A0ABR1V866_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663012.1">
        <property type="nucleotide sequence ID" value="XM_066817320.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050380"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF237">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ATNE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="302" mass="33416" checksum="2E22D46B8CBFC461" modified="2025-10-08" version="1">MPIVGKLGFDKVLFSKIAAGRAKYMAYSKAQLTERTKLGDETDRRDFFYYLLRARDPETGVGFTTPELWGRVQLAAIQLTRATSIIAGSDTTSTAMAATFFYLVRNAAALQKATAEVRGVFSDVEEITQGAGLNSCTYLRACVDEAMRMSPSVLLGGITIDGEHIPEGTVVGTPHYTIHHNGSYYPDPFTYTPERWITGSHKSQDGERVITASEVEVAQSAFCPFSIGPRGCIGKGLAYQEMMTTLARTLYLYDIRKAPGVVDPGEGNPRNEYGRHRVQEFQLIDQFTSLKDGPIIEFRKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8J0</accession>
    <name>A0ABR1V8J0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Capsule polysaccharide biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663041.1">
        <property type="nucleotide sequence ID" value="XM_066817349.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050409"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008441">
        <property type="entry name" value="AfumC-like_glycosyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05704">
        <property type="entry name" value="Caps_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="45074" checksum="70D46368BB8E180E" modified="2025-10-08" version="1">MTQPSPYPIPAGLTPIPEEQLDLRPDSEVDHDLLHPRPVSDEKNIWLFWDTGFAQMHGYAQRNVRTWHRRFSRQGWVVRVLDRLPDSPLNVANFLDVTDPAVFPRAFRDGTLAGRYGAQHTSDLVRWPLLLRYGGVYADVGLMPIGDLDWLWRETVGNESSPLEVVTFTMNGRDLTNYFLASGRDNPLFLRCHQLLLALWAADGGKTTTDGMCNSPLLRGVPKMARTLSFEEDGRVYGPDEVSDLLSDYIVQGQAAALVMGLVDDEGGWDGPRYVREHVWASDYMEASQLVNELTAWDGPKAFALMSLPLPREGKGEEAESEEQRQAREILAHGLILRVLGPTLGSLWRANEGSDDVPGTYAHWLRYGMLHWRQESLPKRWEFEVVEPFKRGPLLREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHE4</accession>
    <name>A0ABR1VHE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010863</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664468.1">
        <property type="nucleotide sequence ID" value="XM_066815178.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048238"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF49">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="5">
        <location>
            <begin position="74"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="467" mass="50932" checksum="357C4379316768CE" modified="2025-10-08" version="1">MKAFHGTVIHSLTLGEIEILEDTLLVVADNGRIELVEPRVDRDEVPALLQARGMTTQNQDGDEGNIHYLARTQFLVPGFVDTHNHAPQWGMRGLGQGLHILDWLDRITFPHEARFADPAHARRVYGRCVAGFLQQGVTTASYYGSRHAAATDVLADVCFEQGQRALVGKCNMDRNAPDTYRDADTEESLRDTEACIAHVRAVDPEGRLLQYVLTPRFAITCTPELLRGLGDIAARSKKSANGTTGHDHPEGMAIQTHFNEAEQEMASTRALFPEFRDEVELYAHFGLLTPRTILAHCCYATDSELDRLMRLGCGVAHCPVSNMTVGGGFMAAPVRTFLDRGVPVGLGTDSGGGFSSSMLDAMRQAIVASNAREVQSKGQLKGLTIPEVFHLATLGGAKVCGLQNKVGTLEVGKEFDAILVNADPALPGVMTMVEEEDSLATVFEKFVMTGDDRNIEQVFVRGRLVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIA3</accession>
    <name>A0ABR1VIA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664680.1">
        <property type="nucleotide sequence ID" value="XM_066815390.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048450"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039965">
        <property type="entry name" value="C3H7.08c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40466">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40466:SF1">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="128" mass="13885" checksum="CE35D3FC2DFE3631" modified="2025-10-08" version="1">MASMIARRAFSTTTRRLAQVDQNLKAETKRNPELYILGGVMCAALGGAGLYFGRTPTKSTSEAPVNMSKEAMPWETGSEAGKYQYHPGGNPANAPKDAPSAVNVVVVPDVDLPKRLHDKYNKWGKDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIL4</accession>
    <name>A0ABR1VIL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-splicing factor ISY1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011251</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ISY1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664856.1">
        <property type="nucleotide sequence ID" value="XM_066815566.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048626"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009360">
        <property type="entry name" value="Isy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037200">
        <property type="entry name" value="Isy1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13021">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ISY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06246">
        <property type="entry name" value="Isy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140102">
        <property type="entry name" value="ISY1 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8071048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="26476" checksum="9A1E50B398720BBD" modified="2025-10-08" version="1">MARNSEKAQSMLFRFREAQAADLGIIDAGRTRRPKVITEVDSIPSCEKWRGQTLKEISRKVSKIQDPALSDYQIRDLNDDINKLMREKHMWEVYDETGREIPGGGKGYRYFGRAKELPGVKELFEAATQKNREEKPLETRDDLRKAVDAKYYGYAPDEEDEALLQYEAEKEKEAFDTLFNQGGGKGEVPKGWESLPGDSGDGKGWELPTLQEVQDELMDRRRKRLLDQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIL6</accession>
    <name>A0ABR1VIL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664785.1">
        <property type="nucleotide sequence ID" value="XM_066815495.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048555"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669">
        <property type="entry name" value="5-KETO-D-GLUCONATE 5-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G03445)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="193" mass="20594" checksum="DF58E3F991AB02E8" modified="2025-10-08" version="1">MSPRLRSSPPGVSPWPSSPRNAERFEEDAGKVPSAAAAATDEEVTVRVETFPVDARDHAALKAALEAVHASLGPSEVVVYNAARVGFLQFGEFTPDELLDDFKVNGVGIYVASVWAMPYLVELAAAGGSPRRHPSFLLSGSGINYSPLPPIFSLSMQKAAQSNLLKSLEQMYGPRGCTSRAWTSTASSGRTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJN4</accession>
    <name>A0ABR1VJN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010709</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664314.1">
        <property type="nucleotide sequence ID" value="XM_066815024.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048084"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF236">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="330" mass="36689" checksum="4CC2809B0CDBAD12" modified="2025-10-08" version="1">MSGPSWMEQFSQIFPPKPQFTEKDLPDLNGKVYFITGANTGVGKELARMLYSKNANVYLAARSEEKAQRAIEEIQQSSSPSSSTGKLVFIQLDLADLSTIKDSVQHFLSQESQLHVLFNNAGVMKPAQGTTTAQGYEPQLGVNNVGTFLLTKLLTPLLAATARREREEAQQHPASVRVVWVSSSAAEAPPSPKGGVPLDNLDYHEPRSWFAQYCISKAGNYLHSAEFARRHGGVGPNNDGILSVALNPGNLDSELWRTQGVLVRKFLQWFILHPPVFGAYTELYAGLSPELNLEQHSGGWVVPWGRPMQIRRDLQEAARTWSERQVERYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VMC5</accession>
    <name>A0ABR1VMC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Myosin class II heavy chain (MHC)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011201</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664806.1">
        <property type="nucleotide sequence ID" value="XM_066815516.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048576"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083:SF0">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="201"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="454"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="624"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="721"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="802"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1006"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1166"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1397"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1525"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2299"/>
            <end position="2445"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1621"/>
            <end position="1795"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1877"/>
            <end position="2133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="28"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="459"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="501"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="749"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="777"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1029"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1040"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1094"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1110"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1131"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1307"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1343"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1357"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1542"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="2323"/>
            <end position="2342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="2353"/>
            <end position="2370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="2380"/>
            <end position="2392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2435"/>
            <end position="2445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2445" mass="269088" checksum="00E47593A30AEC08" modified="2025-10-08" version="1">MFDGLGTPKTSSPRPSTPPGASAQDGIAASRSRTPSSPRSPAFSTSSTVDGSDDQQSSSPIIPSLPAPRLPERAQEHLRRATSPQSRTGSDDDNNYVTTSWGSPYPHSEGKHLRQTSSSSEASDDSPIHHLEIQTPFLRTVPLIAPPDQDHHQTSQLSESAAILVNRVRRPVRSITEDWIRAHTTRNLTSEQRHWLSDEDYSEHSSLSGSVSSDEVGWFEETDPRTPRASSLFPGKSHGHPRTRSSNETLRQATLNLANLDMDNLNVETGRRAQDAASIHTIESDTTSKMETPRLDRMASVNGSMRDAQLPATPSRPMKPGTSHTPRLKKKVPWKGKSIVVHLPRDSERFQPGSKGLKTLSSSDIEAMYESWEELGYNTRGFDLDAPRGNLDPLETSSQSRNEWPNLGDIARERSQRKYQVTLPDLNAWKNYVNEIAEAKLRALGVSFGDEDPAPSISPVPSNLSRQTSGQYPPLPFSPPIPTLSAGSGGPPGFPFPGAFQPTSAAQSPSLVSHSPFNAPGKYNPRASIAISPNELPFFNGQPSPHGWSPHQMLLHNQHLGRSRSPTVMNMSSVVSPTSPFQHEGIPSPLGLHQRHQSLQFPMLPHQFLQRQDSARASPRLQELREVDEEVQVNPYDGQGPEKAPEPSAPFIKHNASASLQKEIDDAEYHLEEQFREQLEHEDYSPHNENQKVEAATTEPAEALPIHSRGPSVHFGNFGTDPAEGPVLHHPRPHSRGHSLTQKAYFDNDEVRDSTDEGSIKKLPAINAHKGDESYEVETNPSNMGTPIQSFDLVNQLHQRDFSTSNNPWADAVSQNGANPSSRRPSHASKPSLSSLNANAAEFKFNPGSSNFTTGGFNFGAPSFQPGASSFQPMSFHGSQASVKAPHSATSSHFNIPQSAASSHFSAAPSTASAKTKITAAAPTFTPQQSDFSFPAKSDFNFSSSGPKFNPDAPTFQPFGSSFAPSITSATASGNESSSNRPTSIFGKIDLSLSDIVKPPAKKNKAIPIIRPSSSHSTAPAPVVSVETDHDEQAEEEQAEGGRTDKGRRSKNFRDSGDDGNDVPLFAEPTPEPEIPVAQLRPAVGKPEGTAQQEVDEDEDDDAAALADTSMASTVLSESNDGKFQSETNDTKATTSPTATSPDHDKVNWNAFEFSRQEEAQEFANARPFDDEDPSFTKTHKKSLSATAQPFTPGFMFGAPNPAAPAFEPSFKTQPAPMVESEASDDDRAASPTPMPEPRPTTEDVPEPEGEMRSPPSPETSPRTARGGLGASRFASSGLGASRFASPPPKPAGLAASRFAKSPSPVSDEETEAVEADGEPPELHSFNDSIPMPVSPPSVAADEPVEKEEPTFEEIDAVMRHLHDNDPTMGVNKTIESPRWHNPSPVRNIPLDGVANDTPLLLPPQQKSFRDNAPSPSPRQYRALPAEPAQPMLSTEMDDPFIDEPTSTVIRSFDAENPAIHHLNGGTSPQSDWEGDFSASEQDKLEQRVQFFDGHVNDVVDNVLASRLHPLEQALESIQHALISRRAPSSRRDRRSVSQELQESDADDEDDEIPVARRSMSPKRDKRVEQIRFAVLDAMKQHQALQAAPAEKTESSLAFDGSSIIQALSDMRVHFEQSLLSDFRSDELRNLEQRLQTEEEKVEKETTLRRGVEDQAAELRRNLEQAETKCMVEVMNRGVYDQRSNDLEERLKIQEEKAESEVKVRREAEDRLSEIQRLLRISSEEEDRLRAVVEEKEAKIKTVEHDAGNNAMRVHLLEAAQSNGNQNQAELTNRLNIQEEELRGSRQEARHWRSEAEHARESIRRQTDDLVHAVDESRHLRKLLDTMGTQVQEYERTRESWRAKYASLQDDLAHTVREMTEENMRHVAKEQHLLARHEVLDARLQAESRTRERLEAELERLEGGERAALRAVSECKRLEAVLLELRNENHKVHQNAMRVQLEAQQAKETAAAEVQRAQVTVQTELEAANEQVNIVRAELEGELAAIRAELEQAKTGVDHAKAEHESLFVEAKAQQEMMLEEEANKLRAELDQVKLDADTAKAHHEMMLEEATNSKDTALQELMRKHQNEVEDLQARYERQVNNTTEDAQRTEQHLLERLSLSTSKVEHLQDRVSHLEDKVQIAQEAARAAAQAAKAAGAIEPATHAAALGKPAVSQAMQLPEKISPQALRESIMVLQEQLQSREQRIEELEHTVSKLDPEAPTKITKRDDEITWLRELLAVRHGDLQDIIGALSADTLDREAVKDAAIRLKAGLQMEEQERERAMNGGSAINLPNIAATIQAATPRVAQAVGPLAAAWGNWRKGNTPSASHASRMRPSPAPARNSTPSKSTIASPASQNSFLSGLMTPPASGLRSTPATEPSKAQPTAFGNTGRRFTAEQYAQRSRGPSMTARQAEKMPLAVSPPPRHMADLERPVTPPMARSGGYDADASRIEDDFDDAGFFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VNC7</accession>
    <name>A0ABR1VNC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665166.1">
        <property type="nucleotide sequence ID" value="XM_066815876.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048936"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="192" mass="21327" checksum="917424EF93CA0CB0" modified="2025-10-08" version="1">MRSDILNEEVGNDQVLLRFCKEFNGWCCDLLDSKTDCCSSDVGFQLNNATLINYDFFQQQRDYTFDLADAYTSVVANTWGSNTARTNSADAKLPTDACPSTLSIALEAGLAAGLGVPLLILLAVLLWMLAKQKYNRPDTTNMSGKGIGLAKLKDVRARTQPDVLQYEYVGGQHKWEKAQLHAEERRVVAELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTB3</accession>
    <name>A0ABR1VTB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009166</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665443.1">
        <property type="nucleotide sequence ID" value="XM_066813481.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046541"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045122503" evidence="3">
        <location>
            <begin position="35"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="4">
        <location>
            <begin position="39"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="4">
        <location>
            <begin position="182"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="46248" checksum="84125EC854AAAF16" modified="2025-10-08" version="1">MNMGGVIEAAASLLRLLGIFALLVCSIFSTGVVGQEGKTPGLGEVLAGQKNLTTFYDLIRLPNLNGVTDPLTSLNGIWNPDDAAVAVPILQYHIVAGQFPADAMQPGAPAFNPTYLTSPRWTNLSSGGQLVRADKQPDGFVALTTGSGSRSSLVPLSADGRLRDLHFTGGIVQAVDNLLIPPTALKETLTAYSDLSFLGALYAAGLYDEFAQCGTNGNCTIFAPSVRAFRAVNSTLAGLSRDDLVKVLRYHIVPGQVLTSNLLLNGTMLPSSTSSPGQQQQQQQQLQVRRAGNYLYLNSAQLVQQDILFANGVVHLLDNVLNPFLSPDAVAAATPNPELGTQPPVFRTGSADAAMATVTEASAIDALPQPFTTALPCTVSCPAPTEAESGANGAGVGARRTSSSTLGLPTSTSKGQAAAARCTGLVHPAAAALAAFGVGVGGYWGVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVI8</accession>
    <name>A0ABR1VVI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009870</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666147.1">
        <property type="nucleotide sequence ID" value="XM_066814185.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047245"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09839">
        <property type="entry name" value="M1_like_TAF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057345">
        <property type="entry name" value="Ig-like_TAF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037813">
        <property type="entry name" value="TAF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057991">
        <property type="entry name" value="TPR_TAF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15137">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15137:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25316">
        <property type="entry name" value="TAF2_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25577">
        <property type="entry name" value="TPR_TAF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 2 Ig-like" evidence="8">
        <location>
            <begin position="550"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 2 TPR repeats" evidence="9">
        <location>
            <begin position="739"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="655"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="912"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1198"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1258"/>
            <end position="1719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="263"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="921"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1258"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1310"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1333"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1375"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1416"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1445"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1477"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1611"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1644"/>
            <end position="1655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1670"/>
            <end position="1685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1719" mass="190860" checksum="E042034854F4EDDD" modified="2025-10-08" version="1">MPGAIIELDQVPAQEGDAGASGELPIEDTPVHPYSVFREQVWLDFDLREKAVKGRADIFISVTDDSLDEIFIDARQCSIDLEKITVSGCPAKAVYKDPYAAADTPAGYEWGAQQWPIRKHRMRSLLHRRRRELSATDHEKDNSCTPLDGSLRVTLPSLKDRQAGLIKLRDAPLEQKQKPDPADKHLQEMNGKLFHKITIPFTLRNIRDGLQFVGVDEADSRYPHLYTLHSVEPGIASTLGDGFQRAPVTQTSGLLNGNRKRKHGEEEPRRRRGDAFTEEDKLLELTAVCSGKLEDETLDSADETKKTMTFECHNKAARHIGFAIGPFEHVDLWSEFRTEEDDNKLGSNATKVHGYCLPGRAEEVQNTCAAIVTAIDQFAMNFGRYPFDNYKICFVDDMVANNVPLCGFSIASTRLLYPCEIFDTEIETTRILVHSLACQWFGINIIPNTSADIWLVVGIAWFMTDYFMKFICGGIYGPESTPGAFILDRRLSKSSSSAPIVRLINKMVSKANTSGDQGDEILASEPFRKACEKQGQTRLESFWNQWILGSGCPRFDVYQKFNKKRLCVEMTIRQVQDIAAHKARALDKNAFWGDVLEETHSVWAGELQHCFSGPMTIRIHEADGTPYEHIVEIKEETAKSIKFEIPYNTKYKRLKRSRRQRDRQIAANTNKNTEENQEDGALLYSLGDVLQGQDDVEEWGLHDWNEDQEAQMDQESYEWIRMDADFEWVCTMKTNMQPYMYVSQLQQDRDVVAQQDSMLYMELLSHKNGAHPLASTILTRTLRDLRYFHGIRTMAATILQLHAVDGPAERIGLKHLLKVFQTFFCYEGTYTPRPNDFYNKQQYLIQCSIIETVAKVRDRDGKCPEEARRFILEQIQNNNNEENCYSDQFYICKLIKALATCQIPDEKKSKTSMSMSMSFGDGDEDEDGDVAVDKEPQEFKERALEEIDRYRRMDEYSPSYQNCFTVAALDALCQMMKAKVIPSDPLVFVQYLQDKTIDVVRIKGFEAMVELGHMSHPVFLRFLLSVIGTDSSPFVRSRLFKILCRGLASIAIGEHEDPENDKPAGNESGLIVDDTALEAKQKAKARRENLNLALSALKEKTKDDLVMQEVVWNTLDSPVLTVAERRNMLDMCSILFEEDEQLTLRFNYPVYWTASRGEKQRNKVTSSPPRNYVYSEALTNHWIQIHVNFHRHYRTQSRKKYKSYAEPPSASSAKPEQPKRTITLNLNTLNLNKNPSLGPVKAASPSANAVPPVVVKPSVSEAKPIPKPAAKPAFKPASKPAPSVVKSTPTVTVSASRPEPKPKSASPVKDALKEARRDSISVQAPRPSAEKPSAAVGAVPATPATSAKAMSPATSSERRALPSVGSQPKAPGFSKPRDDFGKPRDGPVKIKEIKVREQTPKPPRDRDSPKDSLPVKLKENSSKPKDGLPKPPKDRVLAKLPTFISKSSGSLPGKSSGSLPGKSSSSLPGKNNGGNSGKSSGANSPASLAPQIPKSLKRQSNEPSESPRPTKIVKLNTKGLPAHIFKKRSKVVTVKFKAWDKLKRKPSPARTATPDAGSIRASSKSQHLQSSKHQHRAGSVGFSKHSKSHSPHVSTPTSTGNNSFPSPPMRPTQTIKTSSAKILSGTNNGGNGVKAIRKPLPGSTPGGGGSSGGSSGSSNDRRPLPSAGRTSLPSGGSPHTSSSHPQQPPPPNSTPSTILSGTKSKIKIKVKPTSSSQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY71</accession>
    <name>A0ABR1VY71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peroxisomal membrane protein PEX13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Peroxin-13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_009517</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxin-13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665794.1">
        <property type="nucleotide sequence ID" value="XM_066813832.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046892"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007223">
        <property type="entry name" value="Peroxin-13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035463">
        <property type="entry name" value="Pex13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332:SF1">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04088">
        <property type="entry name" value="Peroxin-13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 13" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SH3" evidence="15">
        <location>
            <begin position="291"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="370"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8074854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="413" mass="43041" checksum="63AC04681CF4D875" modified="2025-10-08" version="1">MAAPSPTASGASMPAAPSSLSAPSSISTATDSSPAIPPRPDSLASSVNQNASAYSRLGSSPYNSAYSSPYNRYGGYGSSMYGGGMGGYGGYGGMGGMGGYGGMGGMGGMGGMYGGMYGGGMNPNDPNANSLTNTFNNSTMATFQMLEGIVGAFGGFAQMLESTYMATHSSFFAMVSVAEQFGNLRDTLGSVMGIFTLMRWIRTLIAKITGRPPPADATALTPAAFARFEGRQAPPGGTPAQPKPNRKPLVFFLLAAFGLPYVMSRVIRSFAANQEEERRRLEVANASDATSQLEFCRVLYDFAPQTGAQGTDLAVKKGDFVAVLSKNDPQTGAPSEWWKCRSRDTRVGWLPATFLEIARRPGQPLAAIKAAASEPANTRTNSLTSAAAPMPATAGGKPSDATLEGFQKSQFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7C6</accession>
    <name>A0ABR1W7C6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding protein RFXANK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666868.1">
        <property type="nucleotide sequence ID" value="XM_066811526.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044586"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="361"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="572" mass="62083" checksum="23430CEC18BC2E4B" modified="2025-10-08" version="1">MDQTKDGLVIRDPQATGDEHPQLIPLYDRKHYPAGFYPVVRPYMKGGARHCDTDYLAQVLQAWSPEIDQDNAINAALFEAIYRGDEVAAQMLLDAGVSPRRPQRSDPQFTPLQAASQAGQLGMARRVWKLVVAARNGRPELVAFFLDVWGGWTAEERKGALDGAAWTRWDGCVDVLLAELTYEQKDLQVALEWAIRKRMILPEDETGCLRRKQLGDARLRQRRIICNLIDAGANPDGPGLWAKGGRLLLSAASQLDYTACMGALLEKGANASIQGSDGATALHVPLRKRSLVSHLGYQDTPQDRMAATQLLIDHGTSPDTANEAGETALHLAAQNGSFKQLQLCLAHTRLANDGVRRPNHRGESPLHYATASGREEIVEYLLAHGAADDVNRASSSGWTPLLCALSPSQGKSEEMAVRVAARLLTAGASARVVTAEVWSPLHAVGSWISGPAAEKALRYFAEPCYDPVARAQFVQLAHELIQRGAPLDIEPAFLRHSTIAPDKLDGVWGFRLQKLAESTKQEENAARSVKEEGAGSAVSDTTPLAWAIRTGAMDLVQVILDALGSSTGGRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7K7</accession>
    <name>A0ABR1W7K7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_007283</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666940.1">
        <property type="nucleotide sequence ID" value="XM_066811598.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044658"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF2">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045594439" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="12">
        <location>
            <begin position="20"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="13">
        <location>
            <begin position="20"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8079465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="245" mass="27737" checksum="5D370E52D1803F76" modified="2025-10-08" version="1">MKNLSVLALAALSPALTLAHYHFPHLIINNQVTGAHEYVREHDNGYMPSWDDGRFLDSNDLRCNKGSENHRTQPKTAKVVAGKDVVGFATNVQAEIQHPGPLQIYMSKAPGDVRDYDGSGEWFKVYQLGHRDGSTEDKAWLSWGQKQFKFALPAEIPAGQYLMRIEHIATHQPYKGREFFLQCAHLQVESSYTGAKPANTFKIPGVYKRDQAFFQYDSWAKPQPKTCPMPGPAMWPNNNNFNKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7W1</accession>
    <name>A0ABR1W7W1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007315</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666972.1">
        <property type="nucleotide sequence ID" value="XM_066811630.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044690"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF11">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="651" mass="72587" checksum="C6E69728F14672E4" modified="2025-10-08" version="1">MSQAVSRKGSDQSAENNKPGSKTKTRSRNGCPLCKAKRLKCDETKPECLMCLKNGRKCPGYNQSFRWSTKHEKSLSGQAKGPPNMKDLVTETSKTIAQDQPVGHETLETEPIIVDHLDGLENLEDLEHPVLTCQPPGDDVIEQPLALTPPPSADDRTPFNLWDSSVSFCPPARVVYPQIPRLIHDRSSLLVEEWFRHVCSMWSSFDSEVNLNRKLASETWSSSEAVMNCLQSMSATCLAPQLPYMKQVAVSYLKNAIKAIQRDLKSQAATVGKFPSDLLLALCCVGTAACWIDTKELGSQFLRETKALLKRINRDSDSLSIQDRHTLSFFNNNLIYWNMLVAVVSDEIDDLGIPKVKEPLNGEMTGARHASSVDRDLSNHAETTAMRDIKEAQEIEEEILGLETYQLHDVTDTGDRNTPRSHFVHVNEGYRLASLLQLYQTFPDLVARRLPEDTTEAAGHVPWDRWIVPLSLRLVNTLKKVPPNSGTRCITPLLYLSASTGLRFDAETIAQQQKQLQQTAQVQLPPEVSLNDAVPDGGNNIPVVDGTGVPNNGNNNNKGSDSNNIAFSMNMDDQEDEEMSITRLSVEVSYARRFIMERLSAYEHNLPPAPVTVAKELVKAIWAGYDSEKPGSNYTHWIDVMEDSNLRTIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8W0</accession>
    <name>A0ABR1W8W0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ysc84 actin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667391.1">
        <property type="nucleotide sequence ID" value="XM_066812049.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045109"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11524">
        <property type="entry name" value="SYLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF8">
        <property type="entry name" value="DUF500 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="2">
        <location>
            <begin position="157"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="698" mass="74918" checksum="BE8BFAD9977B3DDC" modified="2025-10-08" version="1">MQRVSALLPSWGDRSSRSSAGSTGKNSLDKVRGWADIIPSPNNRLSGSRYGREAFWAGTLDKECEKAARILQAFCREGLVAPDDRPSSPTTTSSNQTTSQVLKKIPPRIIQNAVGLAVFTSMRSGLWSSTGSGGSGILIARKSDGTWSPPSGLILQTATLGFLLGVDVYDCVVVINTFTMLEAMGRPKVVLGTDVAMTTGPLVSLGLWENEIRCTDLSDTVFTYVRSKGQLAEVKLEGTVLNERTDENERFYGNSFSVPKILAGDVNQSLPQLRPLTEMLKAAEGRTDFDHSLLEQLSAHPAPSDASIDSSSSTSSLAPLFGIPDMDDPDPYGVLALESAGLEIREAGSRLRPDSSQFEFCPSPSSSVFPRAGRHSVDTYSLTRSNRGSYMSNRTMTTERSHLTDAQTQTEINTPNTTPSPEQSEDGHQINSSSDAKEPEVPKEPEEVDYTKIDISALRKLSAFPDLDEPIVMTTSPIKEESLDMHANDHGSQTSTAQSETENGADADDEDDQDDSDDDVDGEEFEDAEEPVVYEVATAQPPRMAIVASQAVQVKGSVVTIPRRVPPPLPARSSARLSRQNKSDFGDASAVNMVGSPLRQEFDLDQAADEAATPKADEKFALPLSAPSSPAQAEGLPLAVTEGTAVKSTITPSETSEKSDYTSRPTSNTLPENAEEAALAPAKEAQHEARTEATVLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9F0</accession>
    <name>A0ABR1W9F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007963</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667620.1">
        <property type="nucleotide sequence ID" value="XM_066812278.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045338"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF45">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="446" mass="50199" checksum="50A2E20F02E5C30E" modified="2025-10-08" version="1">MSDTADSTLGDGDSYRQTTPSGPSAPQQAQPISDMNAAMKVTRGHSCILCQQRKVRCDKSKPCSNCVKAGVECRVVPPQPPRRRKKRVPERDLVDRLRKYEAMLTQHGIEFEGLGPDVKILDPGTVQEGDELDSEFIKVRESPARSDPDLISSPGETPHIPSVLIPDSRTFKWFPFQKEFRAIEEEEEVHRESSDDDDVGTTINTAYDKMFDNADGFPFVVGASSRSITDQHPSAIHIFQLWQIYLTNVSSLLKMTHTPTLQGRIIEASANLGKTSKSLEALMFAIYLMAVTSLQDDEVLEMFNEERAVLLKKYYMACQQALLNASFMRNPDLTILQAYTLYLFGIRPFIDPRSLFCLTGIGIRLAWRMGLHRDGQQFHLSPFEVEERRRLWWTLAGFDRRIGEITGSTLTAISTGGDCKLPLNINDADLHLHAKDSPTPIPARRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAX8</accession>
    <name>A0ABR1WAX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668129.1">
        <property type="nucleotide sequence ID" value="XM_066812787.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045847"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="192" mass="21665" checksum="020696BE0B00954D" modified="2025-10-08" version="1">MRALREAMPELTPLPIGTGQYASDPDKFFYLCEFRDLVEDVPDIKDFSSMVAELHKRGVSPDGKFGFPVMETAFAVEEESQGADADMQALRVAIMTKVIPRLLRPMETGGRSLVPRLVHSDLWHGNVAVDVNTGLPVIFDGIALYAHNEYELAPWRPTRHNIGRPYINEYLKHAAVTDPAEDFEDRNLLYCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB13</accession>
    <name>A0ABR1WB13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667702.1">
        <property type="nucleotide sequence ID" value="XM_066812360.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045420"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034:SF1">
        <property type="entry name" value="CONDENSATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="524" mass="57803" checksum="8A2A842C9020C847" modified="2025-10-08" version="1">MSATANHPWTLSSPGVYTQTHDSFAQFFADWVARESESERTSLIVVSVVKIRARFRSSSDTHPAGPQIKDDLMQMRLKQAWTAMRNDHPGLAVEFGPNHSTYKVPTQKDDLVAWLDATFLVHPGLDARGLTRSLKREAQPRLHWLPKTGEVVLTMHHCYADARSTWVFWDALLEKVVKGASPAMLDLEKSTKPPNLPPSRDDLLGLPSWPSIQGWLKAHDLLVSAMKLDLVLLPPSTTIPAAGESKDWLSGPGDFVRHSISESRTAAVVAGCKARGITVAAAFYAALASATRALQETERAGSGGSHAVTFHHFDVRPWLQATGNTNRVGLGVDYHVIIPFALGMIIPSPVGAAETKGEETVQERSLDELAHDMNEFFQTTRHEFGQDPTGLDALTHYVHSMFVPSTPAPSAPIFSSLGVAEHFIRRSFSGREEGEEVCLHESHGCEGEEEESFRSSRGPTLELEVEDTYVMTLGAKLMNCVILHTFRGRIWALSGFDESYFRDSVLEGLLAGTFEKLLAWLDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBI0</accession>
    <name>A0ABR1WBI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668273.1">
        <property type="nucleotide sequence ID" value="XM_066812931.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045991"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="364" mass="41864" checksum="ED66B964E64C8562" modified="2025-10-08" version="1">MEEALIVSENMPDYSCISCGEHPVVGQNKTFEACRIAAQDRRQQQALNRERVDKEWAQKYGKDRPEGGEREPARCVLCRATPAMDGEPRCYNCTMIGHARAAKDLRRNEHRRAKTQAELARRRRQELIEQGRCHRCESEWPEDGQQECAKCGEAGEARKKAAAERKRELRAVRYASIKSQGLCAQLGPEAWERKLRAQQQRRDEIKRMWLCVQCEKALAESGKTRCAKCLERVRKGAVDPEAWQRMLRVQKQRREEIKRKGLCTLCRSRPPRAEMTYYEPCALEKSRKKRGIKPSAREDDEVRHADEPMQDVQDIDGGDLYALGEEAQESHPVPAVEEQENSRQGLLDTVSQGVDRMAIDFLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBK7</accession>
    <name>A0ABR1WBK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667882.1">
        <property type="nucleotide sequence ID" value="XM_066812540.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045600"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="72" mass="7647" checksum="41B47B19131F310A" modified="2025-10-08" version="1">MATGEVREPDCSAAAAAAAARSPLPDYDTGDEGDISTFVPDTRTTTDHDIPKVEKDDDQIRTEETGCVSMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC59</accession>
    <name>A0ABR1WC59_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668578.1">
        <property type="nucleotide sequence ID" value="XM_066813236.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046296"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8081103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="112" mass="12426" checksum="A6567F13D1645E19" modified="2025-10-08" version="1">MLGIRHERLEHSSPDHLSKPLELGIQAVFDFADVTQDLIDASSLLRVHILNQSVIRETHLVTNTLDQALDHLDSLFDMLVVEPIVKGRPEPVPRGAVPLHAVAEEGEDVLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCG2</accession>
    <name>A0ABR1WCG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_009015</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668672.1">
        <property type="nucleotide sequence ID" value="XM_066813330.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046390"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF38">
        <property type="entry name" value="CHITIN SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="820"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="856"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="890"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="934"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1059"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1089"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="11">
        <location>
            <begin position="398"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="190"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="247"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8081197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1156" mass="129605" checksum="4FCF289481E082B8" modified="2025-10-08" version="1">MDGRPPDYSYGNYDDDLDQIPTAGSGVRLLTSMEEPQPESRPYVIPQLSLPPQLCLPPPSASQSRQQVQGGTSNSPEAPATTPEHFDQLRKQEEAPTPKCVSFAEPLGGESSSSNNNNSSKTSKRKHILGKSKRTPTVRLQKKHRRPSQATEADVAHNLPTIPEGPSPRRASLLSKPPSGERSLAAKPDQPSSSAHSHKTPNSIRPTPRRSYAPSSYAPSFNSTRSSIIDPPHIPPPEPSYYHSRDTGSPTRPWTPSRMSTTSDYSHDYSRDYSRPPPSSVQYEPVDINGSPRPGTPSSRYGGSPRRPLPPAPLFSAQGSAFTADDATVNIPLDQDDDVFGDGTDISDRHYARHSYATQSQYTLNDEPETPYDDKVEHYGPAPDGHQERRGVRAPQVVKKEVQLINGELVLECKIPTILYSFLPRRDEIEFTHMRYTAVTCDPDDFVERGYKLRQNIGKTLRETELFICVTMYNEDEIGFTRTMHAVMKNVSHFCGRNKSRTWGETGWQKIVVAIVSDGREKIHPRTLDALAAMGVYQHGIAKNYVNQKAVQAHVYEYTTQVSLDSDLKFKGAEKGIVPCQLIFCLKEKNQKKLNSHRWFFNALGKALNPNVCILLDVGTKPGNNSLYHLWKAFDTDSTVAGACGEIKAMKGKWGMSLLNPLVASQNFEYKMSNILDKPLESVFGYITVLPGALSAYRYHALQNDETGHGPLSQYFKGETLHGQHADVFTANMYLAEDRILCWELVAKRSERWVLKYVKGCTGETDVPDTVPEFISQRRRWLNGAFFAAVYSLVHFKQIWTTDHTLARKVLLHIEFLYQFLQLLFTYFSLANFYLTFYFIAGGIADPKMDPFGHKIGLYIFTILRYSCVLLIAMQFIISLGNRPQGAKKLYLVSMIVYGIIMFYTIFASIYIVVKQLTEKEQELTIGNNVFTNMIVSMASTTGLYFLMSFLYLDPWHMITSSAQYFMLLPSYICTLQVYAFCNTHDVTWGTKGDNVMKTDLGGAIGKDGKVELEMPSEQLDIDSGYDEALRNLRDRVEVPEPGLSEAQMQEDYYKSVRTYMVVSWMIANAILAMAVSETYGSSGIGDNFYLRFILWSVASLALFRALGSGTFALIEVVNMVVEGRVRMSIKVPQWMGGFGDKVSEKMSSISSSVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WES6</accession>
    <name>A0ABR1WES6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668481.1">
        <property type="nucleotide sequence ID" value="XM_066813139.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046199"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.20">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8081006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="346" mass="38643" checksum="C7AA33CCA869DE4B" modified="2025-10-08" version="1">MIFDDKTLHTPGSLTLECHTGSERYIRLAMGFAHCLSLGDSPDKSSKARFLDSFTRLKIGKWTLAGVKIGRRSLRQHYEQLLESDPGQLQWHYREFLMRSKETSEQSASSFLSPRTTGSAKALTTWIEATAWPSSTAAVSHWFCVPWEHISSLSGLAISTAPCLAIISVSLHESSSGGVFPKAALLTAGGLLCVRIWSGRERGPVPPTRRAREGAAPVRRFARLSWRGTRKSPAPESLFKNGGDEFEIIVGGSRQPCFKANHRFAYNAFHPHSKERGTRGSACVCSNRAIWEGDAYGLSQRLHPRVQRYLYRETDNTEGMRELIEPVPELGAEIHSVFLRWLERSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WKY5</accession>
    <name>A0ABR1WKY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668729.1">
        <property type="nucleotide sequence ID" value="XM_066809806.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042866"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40518">
        <property type="entry name" value="ACETOACETATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40518:SF1">
        <property type="entry name" value="ACETOACETATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046892445" evidence="1">
        <location>
            <begin position="19"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="298" mass="32014" checksum="CC679FAE780BBE7B" modified="2025-10-08" version="1">MRITSALLGSLAATAVKTLQPSSGGADDWTNNSTKPIELVPAPWSLHGTVYSIASVLPPSELPVKAYGPLERSSPAYVAAADPVGPYDELLMVPGYFKYPHVDEQGRRSERLNPSITRIYVSQKYTAKNGRMNWNIPKHLAKFVWTDEADGSTTVKVYPHDTTGTNPNAESAPSTLPFFQTTFSPLLGGLPFSTDLYAWIGINATLAQPPLPGNPDAAHGELAGTQQWRAVVPGQASDRSSLGMFDMGQGKGDAVGNTGKNAVGDEVFPNFWPGMPRLTLGLKMENAKISFGEPEIWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLU8</accession>
    <name>A0ABR1WLU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_005766</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 17">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669004.1">
        <property type="nucleotide sequence ID" value="XM_066810081.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043141"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF71">
        <property type="entry name" value="CITRON RHO-INTERACTING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="258"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="14">
        <location>
            <begin position="562"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="73"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="11"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8084495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="637" mass="72529" checksum="7B2A4E7323D21CF7" modified="2025-10-08" version="1">MDPNNRLYLNIGNNEQRLGPSDSRQYPTTPSTFPQPVFPNQQAMAGQQQQQVPNQQYAGGYQQAGNYFMQQGQYQQPQYAPQQGGDYGQGQQPGYQQRSNTPGNDPNVGLAHQFSHQNLGGSARGAQYGSPRGPSPAQRPRTAGSSNQPQPSYSYLNAPMPNQGQRTTEFQPAPERNPEKFGTNANNNQKKCSQLAADFFKDSVKRARERNLRQSEMEQKLSDPNQSAPRREQIWQNGGKKEGRYLRFLRTKDKPENYSTIKIIGKGAFGEVKLVQKKADGLVYAMKSLIKTEMFKKDQLAHVRAERDILAESDSPWVVKLFTTFQDANFLYMLMEFLPGGDLMTMLIKYEIFSEDITRFYIAEIVLAIDAVHKLGFIHRDIKPDNILLDRGGHVKLTDFGLSTGFHKLHDNNYYQQLLQGKSNRPRDRNSVAIDQINLTVSNRSQINDWRRSRRLMAYSTVGTPDYIAPEIFTGHGYSFDCDWWSLGTIMFECLVGWPPFCAEDSHDTYRKIVNWRQSLYFPDDITLGAEAEHLIRSLVCNTEARLGRHGAQDIKAPPFFRGVEFESLRRIRAPFEPRLTSSIDTTYFPTDEIDQTDNATVLKAQALAAGKPVEETPEMSLPFIGYTFKRFDNNFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLY2</accession>
    <name>A0ABR1WLY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669018.1">
        <property type="nucleotide sequence ID" value="XM_066810095.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043155"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14019">
        <property type="entry name" value="STKc_Cdc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF23">
        <property type="entry name" value="CDC7 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="110"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="143"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="505" mass="57710" checksum="D5202EFC7B475884" modified="2025-10-08" version="1">MSRRRVPKEPFQIHEDDPTDLSDVETEESQTQRAEDLEAEAEAEAEVEADEAQQQLEDEEDQENQEEDEPLDEEEGCESDSSDGSEPVDFTVQQDMEKLNYTFPAFKDNYRLIKRIGEGTFSTVYKAEDVRYDRYNNSWDLDARDNQWEAPPPLKTSSSSRSNSRSNPSRRPKKFVAIKKIYVTSSPTRIFNELELLHDLRESPSVCPLITAFRHSDQVLAILPYFRHQDFRKYYPNMTVPDIKLYFRSLFTALAAVHEKGILHRDIKPTNFLYDPEKQRGVLVDFGLAEREGVDHKPCLCHLDQESRRQKIRATYALNASHAGPQPGYPKNDTRPSRRANRAGTRGFRAPEVLFKCTEQTTKIDIWSAGVILLTILCKRFPFFNSTDDVEAMIEIATIFGVKRMRQAGQLHGCVFETNIPSIGAQGFSFEKIMLWSTCRSDGSKDSKSELTDEEKGAVEFLGRCMDLDPSRRISAEEALAHKFLQIDSEGEAEAEGSEEDVMMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMB4</accession>
    <name>A0ABR1WMB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669136.1">
        <property type="nucleotide sequence ID" value="XM_066810213.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043273"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="317" mass="34043" checksum="F58532862E9BB341" modified="2025-10-08" version="1">MARLCTNRPEGFGPMSNLTPHLPTQCFFDSVLAPMPTFLFLVSLPTMVIVSWWRRRRRGGRINNYLYPRSSPYPFPLTNGGNSDSGGGSGSGSRNANTLRRYPTTTTDRQSVATLLKRLLPSLGYYGAVAVILLMQSVEIVQLERASLGIGLLPVVYAGPAGAALLRLTEGQWRRGAHHRGGRRLTSSLLSEALSPFWVASLFLWTGSAAVTATKTIALATGLGLLDRDDRAPLSRADTPYPVVHQFVDLVILTAFYALAAAGEVGMTVRRGKERRAGAGAGVAGIEEDAVQLRESFAHAAATATPAPTPTTNHNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WND7</accession>
    <name>A0ABR1WND7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="11">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_006331</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669569.1">
        <property type="nucleotide sequence ID" value="XM_066810646.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043706"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF101">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047048942" description="alpha-1,2-Mannosidase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8085060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="57185" checksum="E40A62BB89DD509E" modified="2025-10-08" version="1">MVSSAWLLALLGSSSQAYGLRARGPAYEAHPDRAAAVKEAFDRAWAGYYQYAFPNDSLKPISKSFQNDRNGWGASAIDALSTAIIMEDAAVIKQIVDYIPTINFDKSSNDDKVSLFETTIRYLGGLLSAHDLLSSGVSSGTYGINSTQLDAILNQATHLADNLKVGFDTPSGVPINDLLFEQPPRPDTSLTTNGLATIGTLVLEWTRLSDKTGKPEYADLSQKAESYLLNPKPASGEPWPGLLGTNVNVSNGNFMDSSGGWNGGTDSYYEYLIKMYLYDTSRFASYRDSWIEAADSSIKYLASNPSTRPDMTFLAAYNGRDDLSYRSGHLACFDGGNFILGGLTLDKPVYVQFGIELAYSCHETYTATVTGIGPEGFAWQDGSAANTSNNQPVPAEQANFYKESGFWITSGDYILRPEVIESWYYAYRATGDSKYQDWAWTAFKNINATCSTGAGFAEIKDVNAPNGGGFNDFQDSFWFAEVLKYLYMIQSEEAPWQVSATHDNQYVFNTEAHPIKVAGSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP67</accession>
    <name>A0ABR1WP67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Solute carrier family 40 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006608</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669846.1">
        <property type="nucleotide sequence ID" value="XM_066810923.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043983"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009716">
        <property type="entry name" value="Ferroportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660:SF57">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06963">
        <property type="entry name" value="FPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="225"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1241" mass="138548" checksum="1E6EED711DC54507" modified="2025-10-08" version="1">MAPRTTGFCVPGPVVRDVYLIQLLASWAIRSSEFSLVLFLAGTFPGTLLYVSIHGIGRSLAAVLLGPWVGAFVDRQDRLRAMHRAVFCQRASVVLSCALMLMVRRMQHSLTEAHGLTLHVCLCLFFALACVEKVAAMANFVAWERDWVVVVAEAHGLRRQNFNASLRRVDLGCKLFAPSLVGFLDTYWSQLAMCVVLIWNVCSIAVEFWATRRVYNRTPQLAHKSSSSTSSSSSSTSSTTEKLEDEKELLAFSQSLLAEPSASAPTPAAPVLFSLAPWREYVRSPVFLASFSGCILYFTVLYFGGQIISYLFSLGFTSMEVTMLRMASVLSELGGTWMAPIMMDKVGPARAGLFFLFWQVVCLAIFAGPVITHGITTKFVGLALALGITFKRLGLWGTDLSIQYMVQATTPPQSRAVLSTTEVACQQLFELFACVTTTIFSRPDQFLYPVLISYSMIIVATACYSLFVWKMKYNRHHAMIPNDNSPLGEIRMVLWPWSRGIWAWSSQYGFEVLRDSQWHYVDEEVREVRSRPARGRWIEWSPEGRYWVEEGTGAFHRGVSGPGNFVDVNGQRLPVGHIRVDEYGRRMCLNPDKSWSLVGGAGGFLQVLDNPDGTFTMADGTDPDAPLPNAPEQQLPVRLAPIDYTDPIMLWQGLQTTMGPNPPQPEHIEGGVANPLDPNGGYGAAIPGDPSSLPGDPRMTNPAWTRVDNWLAQAFPLNRYPAAGTLDQRLRHLEAFMERLPPPELKFAHTEDEKSLWVSAQIDILVPCAWLWSGSQSAQTTWANGKQPYGIVPDGMLERMGEVGLAQLQNGERRPYFAWSWNTASQEDKDANPSVDLTDDQERWYWNVEPQGYYTPTEPPFEMNRDVGLYKFTITSPAYSKTQTDDWYAEPILMFTTLQDRLQWCPASKYFNTRVEVGPMKGTHFSTQQLRNMASFWYACEPYLSSLFANTATAEPTHGRCRVAWGEPPDRTNWLCRLAENGSKFPAYPMLESLRCPEPTQSEDDLANNGPDEPGIYDEAEVRRVARGTTVVHNGVAPANTFFSRQPTDWDGNVTGQSANLWRLRRHEVIDRIQRAASSPAVALMMSVGAHPRAPTHGYLDLANYAAPVLGADPPGPKRSVCLRMAPATLHCGDISAWMFIVAGVFAQAAHRDWTTLCQLMPPAFELVREGGQQNPDIEAPRFPFGSQTRYSAKFDVFDLLRKLGNVPYLIRYIELEMLNRFDGDGHIFSHSARPAANPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP71</accession>
    <name>A0ABR1WP71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006589</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669827.1">
        <property type="nucleotide sequence ID" value="XM_066810904.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043964"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF2">
        <property type="entry name" value="SPLICING FACTOR YJU2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="295"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="352" mass="39072" checksum="CA026B4E20E86C66" modified="2025-10-08" version="1">MQGFNMGRYVPRTSKGPLNRKHALGHRASKLASQGILTVRFEMPFAVWCGHCPKPTIIGQGVRFNAEKKKVGNYYSTPIYSFRMRHAGCGGAIEIRTDPKNTAYEVVEGGRRREDRTDEPDGEGGQLEIMTDQEREKLRSSAFAKLEKTIEDREQLAHAKLRIEELEDASRAWEDPYEQNRRLRREFRVGRHAREKEGRASEDLRDRMSLGIDLVPAHEDDARRAALVEFNPVVNGNGTGDNAALSKPLFGNGAAAAQKTPSSGVKRKLKSETATARMKGSLVSEIVGNTRAAHDPFLVPSSSNGAAARLSGIKRKRIEEKETELPRKEPPKEDTGMKKASTGLVTYDSDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQD3</accession>
    <name>A0ABR1WQD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007021</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670259.1">
        <property type="nucleotide sequence ID" value="XM_066811336.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044396"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF195">
        <property type="entry name" value="PEP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="524"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="52"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="580" mass="62455" checksum="0B2E4DD5713AAB63" modified="2025-10-08" version="1">MGSPDSKEHDPPTAPQHVEVAKHHRVIDPIPIEKEAQQDVHHVHLGWRSWVVMFVACVAIFAQTFVVVAAGSVIAFIVRDLGDAPISGWIIQVRGPLLMQSVLSPLVGRLSDVLDRKYMASVPPLIAFVGAVISAKATSMSMLIGGGILIGITLATVPIIHAIQAEILPLKYRSVASGLSFMAGALAGITGSLGSGAVTNVNTGGWRYIFWMQAAFHGVTFLGLALLYWPSKNIEYPKMTLQEYVWACDPIGSLLFITSATLMLLALDWLGGAYAPSDPHVAAPLSIGLVCLVAFALYEWKGRPDGLVAHVFFHQNANFALSVFAFAIEGWIFYSAVNSVVPQIVLNLGFADDAWRISVRQLSYQLVTFAASIPIIWYSTRFKDMQTPLLVTFGIFFIVTICYATIRPSWSNAQLGLNVLAGVGQAGPLSMLVACVQFCAPHAFLSTATGLSFSARAIGGAFGSAVLNAIINGRLSAHYASALLVFLEQGWYPGENGHASGITSAVWAAALRASREEYAHAYRLAWASVIPFVVLAFVAVACLKGVKELMTEKVEATVEHAERVEKGGRRTLRLEEDCGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WR65</accession>
    <name>A0ABR1WR65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670046.1">
        <property type="nucleotide sequence ID" value="XM_066811123.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044183"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF75">
        <property type="entry name" value="ENOYL-COA HYDRATASE_ISOMERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="269" mass="29203" checksum="57B991FD1EE55C28" modified="2025-10-08" version="1">MASKTHFTVTIPSIPGHVGGTITCTEPAPQVYLLTLASPPDNRLTPPLCAALLEALDRVEFGGLPNGVLVTTSAMPKFYSNGLDLQLAMGTPGFTEDSLYPLFRRFLTYPMPTVALVNGHCFAGGLMLAMHHDYRVFSGGERGYMAVNELEFGAPLLPPMAGIFREKLSAPVYRTLALEARRFGGKEALEAGIVDVLGGWEDGVMKLVEGRKLTTKGKMGVYGMLKEEMYRGQVALLDARGSEVVKAPVLMEAEKKRKVEGTRRVKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRB3</accession>
    <name>A0ABR1WRB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669475.1">
        <property type="nucleotide sequence ID" value="XM_066810552.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043612"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="48764" checksum="F964A0CFA96A6D2F" modified="2025-10-08" version="1">MRRWLQVQGILGRAVCQSRRGLSTVTPAPNNIERVRVKCGSSGSIHVDLHNLAKVTSSDPLMIYLPPFGDGHSEHLNQVPAFCKKYLTAVINYRWAGAGPVSGYEADEDSDPSSHLGWPMPIHDTLRGYSWILENLTPLTSPRRDVYVFGSYLGASLATSLALTENHPHQRTTIRGFAAYNGIYNWTMFLPDHPIHKLPKTDHTIFWKTFLEMKHQTETLFANPSDLFDPFISPCLFFHTPGLLVPPDFHSSAATRASSPPRSLDGTVDVVDEILAGMMEENPDRPLRRYPLVFPPRKSTLKIPECLILHSTAPTPVYPHRRGSGRLKKIPVSNHFRTQAHELAALVRRSLEKIEFKERVEWDDSFGGFGGFVENIDRRVGLRDVGFERSAFEIPDDAQAAIREWLENRATIDPRDQVEHLVDPENFWGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRV3</accession>
    <name>A0ABR1WRV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006460</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669698.1">
        <property type="nucleotide sequence ID" value="XM_066810775.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043835"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025702">
        <property type="entry name" value="OXD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13816">
        <property type="entry name" value="Dehydratase_hem"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8085189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="482" mass="53482" checksum="6BBD0438A1CAE66E" modified="2025-10-08" version="1">MLRTRFPTAHHFTVSLFGCQYHAPSPDVSKRALIQKFDKLVKDGALHVEKLEQNDLPSKVWTSHWKSPQHFKAWWERPEVAEFWAALPDDAGFWRETVSLPATRAMYESNGRDPHGSAHCGELIPLTEKMGCWGAYRSCMTQDTPDDKFSSPLPDLPEPKPLSDKIRPGRTRITNFPDNICFMVEGRDESAMPPRERAYWDDEFDDLAKQWITNVMTAGAAKGLVSGRACHAFADGKHLGASPFSDGKGVIECATATSTIPETASNGGILVDRIGPTIVPFLYVDSVGLLLALSVTSLRMKYWQPILIAQALLIVICVSLAFYSRMPRWWGKGTPVITNCQGKGASDDSGFTTTASSFASRSSSSSALFPGLDYPQQNLLLFWLDLSHIEHLARYDKVHVKLRHNFLAAYGPGGVMAGGDILLWVDMGILKGDEMDAEYVGCYEGSGFMAYDHDAAFESRRDTKSAGLPVFFDEPRESKPME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWR4</accession>
    <name>A0ABR1WWR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670480.1">
        <property type="nucleotide sequence ID" value="XM_066806862.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039922"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="708" mass="76085" checksum="46BB94327AFD7354" modified="2025-10-08" version="1">MGSTNLGQGYPGAGDHRPVGMVKFVDSDPSGLPLKRKQVAQACVACRRRKVETVAKRGDGGGRDRDRSSSSSRGSSGRSSLPSPPDLERRPSRFVGDLNPEHFLIEATSPHSSRDLSVRGGVGVWHAKQPVHQEGTRQYSAFSSSSSSSSSATSALRSGPGRLLHDLVVAHVRTHCLTCVPPDPDWTVLKRIYLQRLDPLFPAISSLLSDATPPSDPTTAILVRQVASIAAAADPEARDHLRLAADGALLNPPEFRANLTSAAHATLLDCSGLVTDRMLLVRLLLVLAMYVQPCSPDEADLPALLFARASHHLQTLGHHIGGPDEAADPEGYAEVRTVYCCVWALDRLTAAFYGRACILHERDIGWDMDKIIETASNSSSAPLPPAFRVIDIYRPIKKVDVEEEEQLQPVMVDLPILEQMIVDSDATEVPSGLLATLEVFYHSVAILSCKLPADGNGLFPHSLINGRRSHSADRITEIVGSYSEFLRHGPQNQLQQQQQQQQQPAALKLSCTPLLPYAVSLALGVAYLKMRHSQVPLFRARGRRAFVAAAALLRDDPRLGGGGTSWTARTMAGMAEQVLQEMDKASATATATATATTSTTVPADNPAANDIGDENNRIDNQGASVVVGNDNLTTGATSTAAAAAATIPPASSSSGFMYDDNVFEHLDPAFDLDAVDAAIEGSLDFGASSNWFDWQQHNWSFTTPQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX53</accession>
    <name>A0ABR1WX53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002664</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670597.1">
        <property type="nucleotide sequence ID" value="XM_066806979.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040039"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="40"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="311"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8087703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="396" mass="43556" checksum="60DD7D5FDD085053" modified="2025-10-08" version="1">MSETTPVFPPPRNPDDLGRGPLVMGLTWTFTILAIVTTLLRFYVRRCIGPHPAPDDWLMLVAAVFQLVCQVFVTIAFTYGMGKHQADIRVPDEIVPMVMWEWISIVPGLTAGMLGRLSICVLLVRLFGVHKWFRHHAIILTACGVLVNILIIITVFASRTPVQSLWDQSIPGATQWDPNIVLSLMYIGQGFYAIADITFVLIPIIFIWKLQTSLERRVGLIALMAMGLFTAALSIMKGIAADPGPSSEGPKSPDQAYEATLELLWATLEQASVVALGNVPALRPLGRLDLPVISSLAGSLRRRCSKVFSHMSSKDIKSSNSKSSSKNDHVAGPGSHPGEYRDLEMNGNRARPRHTDVWHEVDVTNSTDNMMYDGRIHRTDAFTVSSAPVRANAGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX63</accession>
    <name>A0ABR1WX63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002696</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670629.1">
        <property type="nucleotide sequence ID" value="XM_066807011.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040071"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24124">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24124:SF14">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_25, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="95"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="539" mass="60272" checksum="063C724490141E9C" modified="2025-10-08" version="1">MVKWIIRQTKNVDACDHEGIRPLHVASMLSEDLVHQLLAAGADPAGATLEGLTSLHLAARARESNIVGMLIDALDASKTTSTGEQQRHLDARDQLGRTPLHHACRSGRYETVSLLLSAGADPTLKDNQGLTVLDACTEFEKEQALWADWRKPDLFDSEWLWKTAIPRTWDEYAVGGLKLHDSLRPWVAPGRTLTKYLEETFESHWKRALSIRSAQDVTRLEDIIALLYDALLKRGEADGSRSVEAQMAICLERCKSKRFAYTERVFRHQLFIGTGNKGQPSSMPSDNELSESLRRRVAEFANEQRGCVPGSHIGFDVVEYLLRRREHDILQRMFQQGGPPFPVLAEEEVGRVARLLAQHGFAQLLATLLESDYYGPKVTKSCSHAQHEGRRGVGGSADPILVVAARRELPNMDVMRLLVGKKDVTGKTMNLNAKSRSGQAFFDAEIDHPGLFWSEENEIEPGNNTALHEFAKGRHWWHVTQGLPYLLAAGADPSQQNEAKQTPLKMAEAMLLRYGGEEPFTARAVEVLRREARSPKVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX77</accession>
    <name>A0ABR1WX77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670644.1">
        <property type="nucleotide sequence ID" value="XM_066807026.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040086"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="16103" checksum="F60EAD359F524B99" modified="2025-10-08" version="1">MARGGEPLDAEAAEEVQEEDRFILEVHRRLVLDFEREFSATVEISPLNIGQFEKFWGDYWLVRIEEELAELNRDVMSEDAKHAAEEVGVIWDVAESASSGASSLESSDDEQETWEYWFDELDKIVPPENHEIGEIRQTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX96</accession>
    <name>A0ABR1WX96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002747</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670680.1">
        <property type="nucleotide sequence ID" value="XM_066807062.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040122"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="152" mass="17404" checksum="76FE0DC76B6FCB4B" modified="2025-10-08" version="1">MENFYTLATLRAELKNTLGLDSIEALTDWLESPGVKPFMDEFVSDYLTNNPTANDADYTKVTNLLGANAVMNFAAYDTTSSGSSRPDKTGWSAEKHWVRFIWQMGQYAKTHTTAWQAPREEEMEVWFWHGYEVVKFLKAEYANERELENAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXH4</accession>
    <name>A0ABR1WXH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670755.1">
        <property type="nucleotide sequence ID" value="XM_066807137.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040197"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047482573" description="Glycine-rich protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="166" mass="15495" checksum="D77A4BC8EDDFD6E0" modified="2025-10-08" version="1">MNKFLLAALLLSVNAQALAVPAADNDALIQYRDEPIAQRQDSDGGNSFVQAADQDAAVVQDGQPGPGPAKDGKDGKGGGTGQTGGNHGGGNRGHDGNRGQGSGNTGHDGGKGNGGKGSGGKGGGGQGSGGKGSGGTGSGGAGYGGGGYGGGNTGKGRGGGGGYDHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXI0</accession>
    <name>A0ABR1WXI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670760.1">
        <property type="nucleotide sequence ID" value="XM_066807142.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040202"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="378" mass="42636" checksum="3708D4328B4CFC7D" modified="2025-10-08" version="1">MPPRKHTRSEDDANQASTSSDKRQKKTNDAPEGDEDTGSEKHAPFEYLTLPRPMHDFAKEANHNANNENEEEEEEGPDEDEIDEEYQAQFETGFLQSPIAEHSDHKWFCFWQTWKLLCDWRQAAGFCDPDMFGMYVYNDFAGYGLQEIVERMMVAFDNQFKKKGRDEDTVKHMWAVVAAMAHWLMTAELGPWIGCEDGDRINKTIKAIGTMFLTALNELDKAGLLKADSPIKDLALVMAVYLEWSADLGDYGFEDDDRDEVDAEDAKPNWRTSVVAYAKKAGIDLATSGVFAADKLVTSLEEKDGASIAPLAGQAKADRWGWKKTLASLKKLSAKFGGKEYDITQWTRAERAKHAFNKKDPLANIPEKELKAGNIKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXT2</accession>
    <name>A0ABR1WXT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670839.1">
        <property type="nucleotide sequence ID" value="XM_066807221.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040281"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="731" mass="81425" checksum="2DDFE0BC8A477322" modified="2025-10-08" version="1" fragment="single">DTLSLPGFCQKGSPHCRPRVNLPHSRDFSDSHPHRAALEVTRNPLSVELTRLRPKNRGTGRSSCGFRVCRRVPRRQVSKPRKRPVSKEERLSLKQASGLLENFLCDPYWGTLPPPDGSPSKGQPADTLRTRTGNLPAELPSNDEPCAKSQRERDQRKRFGISDPATWASIHRTLAQQSRLSSIISSGQFADEVPRSPSIPSRTSSQRKALRHFTRELEKYAEAAGAAGKLPVITPTESDSKPSIHTVKPLLPYRSEFQAAGLAVTSEEQRGKLPAEAAAKSPGPNSKRDNKRRNSLPLVNELDGQDDERCTSSIYSDDTYIRFTPEDGVSTAMLELMREKKEDTVQRRPLPWLRKKEAAGKPASPEPNSANKTKVISDGKIRINLEETNIPGGTQSRHQNLPPTDHITQLPLIKRVLPTPPQDLHRDSTRHDLTQESANLDLLGTLNKPVKALGKRPPGLKREDALASIPRVGVQDGSPRERRSKFQNDQTAAKGKYSNLPFQAFIKQVARPQKNSPAPELPRTWKHTISTTSSLERALDAVSRNTGKREDENHRPESYPEQRSFAGPSTNRPRHWQGGSVLVSKRRQKLHPLPAIEDNESCRDAQAVAAQDHPPVELEGQSWPKVASSKKPNGPPPHGDQIQLRTTPEPKRSAVEEALSDLDVFFDYDDSDIKDRDVLRGLQLAVHAAADDSFDAQVRQKTGLRIRRFLADLSSVEVLDNDKITEEQPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYB6</accession>
    <name>A0ABR1WYB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671044.1">
        <property type="nucleotide sequence ID" value="XM_066807426.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040486"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053037">
        <property type="entry name" value="Pericyclase_pydY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115:SF1">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="198" mass="21774" checksum="49A51F4A36C5BFAB" modified="2025-10-08" version="1">MAAPPEVTIHNLSGQWIMNKSLSDDMNPLMELQGVPWLVRKAAAMMNVTARLTQTTDAATGTGSITIETVATGGFKGETKTYKLDGSELRSESKFGVTHVRARWLNLSERDQPLSMGGDGVALDPYLAEDWIEEPCEKLEGKPGYVQVYVVQEGGEGTAEQVFGFCMIDGKRYHVQKTVATKDGKTIKVRAVYEWKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYT4</accession>
    <name>A0ABR1WYT4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671227.1">
        <property type="nucleotide sequence ID" value="XM_066807609.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040669"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="73" mass="8123" checksum="1F35681B8E762B47" modified="2025-10-08" version="1">MAEMVAKVAMIRKRRVLARPRLAASESSSQDISGDSVLLLALVRLSILLWRLWSNSMSVCGDQGRTVHDQKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZA6</accession>
    <name>A0ABR1WZA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003426</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671359.1">
        <property type="nucleotide sequence ID" value="XM_066807741.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040801"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="256" mass="27347" checksum="34C17CBC86F13349" modified="2025-10-08" version="1">MDNFATYPSLRNKRVLITGGAEGIGAAAVELFCRQGSKVVFFDYSESSAAKLLGHVKGIPGASQPQFLHCDVTDLDQLKKCAEATLAEHGAVDVLINNAAAAGASARVPTAGVTPESFDQDINVNLRHQFFLTQHVVPAGSIINMGSITWRIPATDVPVYTTAKAAVMGMTRMHSREFGEFGIRVNSIMPGSIATQRQIDEVLTKEYEDLTLKAQCLKRVLVPAEVARLMLFLAADDSSAITGGSHVVDGGWVGDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZF1</accession>
    <name>A0ABR1WZF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003488</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671421.1">
        <property type="nucleotide sequence ID" value="XM_066807803.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040863"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF57">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="29"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="490"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="698" mass="78164" checksum="70B942614B11E2D4" modified="2025-10-08" version="1">MMAAPGPVTGSDTLQTTAANASGGRNLRSCQSCRARKIKCDRQQPCSNCARVDADCVYPSGRGRAPKRPRKVTESYVADRLSHLEAVIRKLDSRSHAKGPVAGGNNPYQSRDLGSVRLRPSRLMVREQTSYYVNDNALWGNLADEIPLQVEELREMLLDPGSDDESLDSPAFGGSSLTSSSLEMNAAIFGYRSTAHSLQSLHPLLAQAVALFRVFTENVAPMVRIFHLPTLSRDYWDALASLDSISKETEAVLFTVYYTAALTQFRFAVEQSLARANLLNTQSMTLLQAATCFILVLRNEDDSRTPWSLASLVYHTAQTMGLQRDGTRFGLKPFETEMRRRLWWHICLLDNRSSEYHGFKPFVDDLAFDTKPPLNINDSDISPSMPDFPAERTGFTEMTFCLIRVEVMEATWKIYRRSGAASETKENAAEDGLSLEQRETMMKELEEKLQGKYLRHCDPSIPSQLIVSMVLELILKRFWLQIHVPRTAVKGKSTSSQQPQAAPSRPDKAQMRDQLFLTSVEILELSGRLLLDPLLSPWHWHSHTYIQWSAVALVLSELCGRAPSVDCDRAWESVQRVYDIWKLDKRAQKGTLWRPIRTMMAKARYVREMQQQTELKRRGQDSSAAQLGIASATAGYSTALPAAGSRQSGSGMTPPFTYAAGEDSQLDNLTFPGDLGVFEGMFGVMFSMDFSENIFNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZX7</accession>
    <name>A0ABR1WZX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671585.1">
        <property type="nucleotide sequence ID" value="XM_066807967.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041027"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045758154" evidence="2">
        <location>
            <begin position="20"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="142" mass="13873" checksum="DA1AE4D06AAD2217" modified="2025-10-08" version="1">MTRLLHVVLAASLVQVGLAVPAASDVVPTLSVPPIPTLSLPLPPVVIPTGKGKGFPTGKGKGIPTGKGKATPPGKGKTTLEKRQVPTGKGSAPPPPPTGKGKGPVPTGKASASPPVIPTGKATPTGKATPTGAPVVPSGKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X056</accession>
    <name>A0ABR1X056_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671700.1">
        <property type="nucleotide sequence ID" value="XM_066808082.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041142"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045438135" description="AA1-like domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="19421" checksum="845ECC6546FF72C5" modified="2025-10-08" version="1">MLLPLVLALAASCLALSVPRATSRQVDDQAPAIPHIADLVVRKPFDEDPCPSPFPSAPKIHELTVVHRHRKVNVTDAATNDDTQCNVEYGPCAWSGERPPEVPKPDAPKPATCQNEEFKFWFSKFDSMRNFSVEISHTYHDKDTGSDVVHTGDSGWINYDLTWERGYSFRLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0Q7</accession>
    <name>A0ABR1X0Q7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peroxisomal ATPase PEX1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Peroxin-1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_003927</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671860.1">
        <property type="nucleotide sequence ID" value="XM_066808242.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041302"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19526">
        <property type="entry name" value="RecA-like_PEX1_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015342">
        <property type="entry name" value="PEX1-N_C-lobe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF12">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09262">
        <property type="entry name" value="PEX-1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="547"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="882"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="228"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="713"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1080"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="244"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="713"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1085"/>
            <end position="1110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8088966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1195" mass="128028" checksum="BC00CA6287393FAB" modified="2025-10-08" version="1">MAPSQRKNAQSTAAEISLVHLKNCLVNLPSSLVSLLVNVNTPAQNVVVELSYRPSNASSQATNGATGQQSIFVGWTGMPSKRRFAPLVSRDGISSSRGSGRDQEVAAVEIDATLALTLGITDGQKVMAIIHADPPLAHTVNIEPLTPEDWEIIELHANFLELNLLSQIRALPNPTYTPGQGQTAIPHPLTLHLSPTSTANIKILSLEPAPAADVPFVKIAPDAEVIVAPKTRSKPSKSSRESRSVSGTSRRSAKSSASTVRRRSAREEKRPTLFLRGIDRSLCHEWFDEDAAPQDLSVWVDRDLLQTKDFRGVNYVLVNLIRPAGLLPPIDPKKQQKEAAENAEATKASSRVVATLRPWDDPPDSQTTALSASLCASLGCAGLVGGVVKIEVSPQPVAKNTVQQLKIYPFLGPSSKVLEGFRFGGESKAEKEEAAKRITHMYGGSDGILQGPLTDGMVLGTHEGVEFPSGWEGGIVRFDPLPSATTGKESMSWHLGREKALPLDIQAPVPLPTFLENGEHDFGTPAPGSVLVGIDAVLADLKAHVSHMSSVLLSGALGAGKTAVAQSLAKTFRHDYLFHTTYFSCRTLVTDESRVISIKEKLNRVFMTASWGARLGGKALVILDDLDKLCPAETELQVGNDNGRSRQISETICSMVQQYCTRGSGVVLLATAQGKDSLNKVIVGGHVVREIVDLKAPDKDARRRIMETIVHQQTVSPGTANGQNADHSRPTTADGNAVDEEASDWMDGASQPNRGFPTAQTTSDGFLLDSELDFLDVAGETDGYMPGDLLLLVSRARNEALIRSVSEEAGSKSLDIIQLGRVDFDNALKGFTPASLRNVTLQTSTTTFASIGGLRETRRVLLETLQYPTKYAPIFAQCPLRLRSGLLLYGFPGCGKTLLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFERASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSLICDFPDLEDRIDILRALGSKVKLSDEILQSGEALQELGRRTEGFSGADLQALVSNAQLEAIHDVLGDMEAQPSGKSRQSAATKTNDAGNQAIAETSKASAKGGGSMANGTGQQRDEKGPAAGGGEVVISWKHIVKALEGTRASISSQERNRLERIYHEFVVGRSGEMRDGQGSMEIGGRSSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0T2</accession>
    <name>A0ABR1X0T2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003982</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671915.1">
        <property type="nucleotide sequence ID" value="XM_066808297.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041357"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="9">
        <location>
            <begin position="52"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="10">
        <location>
            <begin position="207"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="30031" checksum="1BFF51ABA30FF0EF" modified="2025-10-08" version="1">MSRPEDTLSADVHYDDTEARKYTTSSRIQNIQASMTHRALELLDLPSPSLILDVGCGSGLSGEILSSLSPEEGGPHVWIGMDVSASMLDVALQRDVEGDLLLADIGQGVPFRAGTFDAAISISAIQWLCNAESSETSPAGRLSRFFNGLYASLKRGGRAVCQFYPKNDEQKKMITGAAVKAGFGAGLLEDDPDTKNAKLYLVLTVGAAVVDGKSGDITGVVQGMEGVDVMDARNRGKTGSGEIKKGSKVWIVKKKEQMERKGKVVKATSKYTGRRRRVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2J4</accession>
    <name>A0ABR1X2J4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672484.1">
        <property type="nucleotide sequence ID" value="XM_066808866.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041926"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="275" mass="29463" checksum="A163DC45A594A221" modified="2025-10-08" version="1">MQKQEAAPSAPAELSIPAPIAEEKEEEDKTERDEPSNESNQESPSQSDEITDSDPETGADEIPPPPATRGATKRGLRRGRRGRRLCRPLLQRGGRSPGVHQGLAAAARRAERARGALPGRKPARHPDLRPRVRADEAQPGARRRAPPRPQRAGARRDQLALPHAPAVPAVAVPAAVQRRARRARRPGVARELPARDGGAQLHHGGGEGWPRETSNETGERRATTTTQAAEHAAAPDRGGRAPAAARGAGRPRHEPDPLDPARARGRDDGGTSHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3G8</accession>
    <name>A0ABR1X3G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WH1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004916</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672849.1">
        <property type="nucleotide sequence ID" value="XM_066809231.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042291"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01205">
        <property type="entry name" value="EVH1_WASP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033927">
        <property type="entry name" value="WASPfam_EVH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000697">
        <property type="entry name" value="WH1/EVH1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00568">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00461">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50229">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51082">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH1" evidence="3">
        <location>
            <begin position="17"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="WH2" evidence="4">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="251"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="541"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="345"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="556"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="596"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="605" mass="63525" checksum="F79BEFC4F50162CC" modified="2025-10-08" version="1">MPSILSDEDKETVKRTVPKQTNKIQAVAVARLYVAFPNRSKWTYTGLQGAIVLANDLVGNTYWLKLVDISPSARGVIWDQEIFDIWSYNQDRTFFHTFELEECLAGLSFVDEKEAKQFKKKMDEREKNASKATRNTPFGGSNHAQPAKHGGLFGGIFGGHRHSSAPSPPESPRNGGGLPPPPPAPASTHSRSPSTSANGVHKPASEFATLEAYDPLWRENFGNFLTEQGLTDEFIKENQEFIVGFLQEQGGEVPKSAPAPPPPPPPVNGHSTGHGRAPPPPPPPPSSSRPPAPDSTSSAGSRRGMPPPPARTTQIGQNRCRYARTYTSARFNTPSTARSASAAPAPGPPPPPRPPKTPVDGHEDSSHKFGRPGAAPASARHAFRSLTSTITAAKGTRLKRTSGAALIIKTCSGTPTKECTRSSTCPGFGRTSAAALAEHECTTTSFAEYKCTTTTPSAELKRTTAAASSELRRAATAAAASDAGCVWSYVWRTPTTSSTSAPARGGYGSGVPAAAIPKPDSSRSAMLGDIQKAGGIAALKKVDRSQIRDRSAATVGGSGDTGGSGAPAAGASSGGGGMADALAAALQKRKQKVSDSDDEDNDDEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4Z8</accession>
    <name>A0ABR1X4Z8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673377.1">
        <property type="nucleotide sequence ID" value="XM_066809759.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042819"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045830534" evidence="2">
        <location>
            <begin position="18"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="718"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="738" mass="73177" checksum="4DE495AE5581CF8A" modified="2025-10-08" version="1">MHGHFSCLLLAAAGVQAARWSPERRAPDADTAPSVPRSPYDDGSADAVEARWGGGGHGGYGGGHGGHGGGNNGGNHGETTVTDTATVTATHTNNVWNTNTATATVTATHTNNVYNTNTATATVTATYYESYYNTNTATATATATVTATATYYESYSNTATATVTATYYESYYNTNSYTATATVTATYYSTATASYYETYYNSNTATVYSTVTVGAGTNTVYNTNTVYNTNTVYDTVSVGPYTNTVYSTVTAGAATNTIYSTVTAGGATNTVSVYNTATVTNYRTVVSAAAAAAPGTVTVTNYQTVVSAAAAAAPGTVTVTNYQTIVSGAAAAAPGTVTVTVVSAAAPAAPQQVTVTNYKTVVSAAAPAAPNTVYNTVYATSTVTQVQAAAPVANSATTKTDTNTYTNTHTYTILVTATETHTATERVTYSVAGAAPVYGTSAAAAVTASSSQYGTSAAAPATASSQATYPTAVQSTQAASPQTASSVQSVSSVYATPASSSYATPASRVYSTSTIYGTSSVYTTAATSAQAATTTTTGWSSSGPWTTGTASNWGSGWGSLSTSIWASSFPGDAAVTLGSGSGNGGTFGVPFASSVGAGVFTASTGGAYTFPGGPAVTVTSGDVLSFGNGGVFTVSSGWTGTASAWSSGWTGTASTWTSGAFATAGASAFISGGGVLSGSQFTVSSGALPTGGFGGVGGSGVGGGIGGGFNKKLVNENGLPLNGTRGPQTTGFSTMTYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7Q4</accession>
    <name>A0ABR1X7Q4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_001843</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673454.1">
        <property type="nucleotide sequence ID" value="XM_066806158.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039218"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09769">
        <property type="entry name" value="Luminal_IRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.180">
        <property type="entry name" value="KEN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010513">
        <property type="entry name" value="KEN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038357">
        <property type="entry name" value="KEN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51392">
        <property type="entry name" value="KEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="771"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="domain" description="KEN" evidence="15">
        <location>
            <begin position="1039"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="60"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="511"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="657"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="657"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="690"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="716"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="799"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8091482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1177" mass="130464" checksum="1F17D2D121147CB8" modified="2025-10-08" version="1">MWRRPPGEGRLVAEQRKAKVFFALAVFVLPWLTLVDAQQQQKQQSLQYQQPPVANILRGDAASRQHQPRVARQAEYDGQENDVNVAQSSRVKKPTRNQSKQPPTPNDYPGNKNNNPSYDASALATVAPDTPVRASNSPRQLSSVLAGAGLSSLHYARSLGRWEVEDYVLLATVDGHLYAVNKESGDERWHLEVEQPAVETIHHRPNNTLLEDYSYHPLDDHVWAVEPTQHGPVYLWQPSGPNSGLNPTGFTMKQLVDDLGPYAVPDPPVVYTGDKKTTMVSVDAATGRVLKWFGQSGSQVDQGATCFRPNGLVDSSSEACTSTGIITLSRTEYTVSIHRQDDGRALATLRYTEWGPNSYDQDLHRQYTTTQNGRYITTGHNGKLFTYDGNGAEPTMSLQLSVPVGRVFDVARPGDAPQGSNPELVLLPQPIPPTRNDEDALARASSIFLNRTESGGWYALSGAAYPLVLNAPVAEVQSKDWADSDNTWSFDDAFVNEALVGKHQLGRIHGAQGTGRMSWPQPLPALPQEPEFPDDDGSNNASLATVPDDGSDLATIVEKVKTLPEYAYARVRDFFTNPILFLLVMSAAIWYLKGSHVIRNSPKYEAPTITPSVKSDKVITEGAAQLPNMDAPTQAVAGEAQAVNNENNPADAAVGAEEAAVAAPNGGLENPLQAGADPQQPVAAPESPEKKKRKTHRGTRGGAKHKKKKQDQAQGQDDKSQHSDHGPTQEDINQIKHIPQETHLQPNVKSVVDDPRDISATGFETTNGLRVNLDDQLGMGSNGTVVYSGTFHMREVAVKRMLAVFYDIAYQETQLLLESDNHPNVIQYYAFHQENAFLYIALERCHASLADIVDKPHMHRDLARAGEMDIPNVLLQIANGLSHLHNLRIVHRDLKPQNILVTMTKDGRPRLVVSDFGLCKKLDGAQSSFGATTAHAAGTSGWRAPELLLDDDAREGSASMSSSHSESSQLVSSGLMPNRRATRAIDIFSLGLVFFYVLTKGCHPFDCGDRYMREVNIRKGQLNLQPLDILGDFAYEAKDLIRIMLLPEPRDRPNIREKEVRDPPSDALQTLEHYAPRICRGDFLKLLTKDFVESLGKQRKYTGTRMLDLLRALRNKWNHREDMSEALKKSVGTSHEEYLGYWSRRFPDLLATCYEVIWVLDLQEAVRFKEYFEPMKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8I5</accession>
    <name>A0ABR1X8I5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC-2 type transporter-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_002094</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673705.1">
        <property type="nucleotide sequence ID" value="XM_066806409.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039469"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="454"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="520"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="632"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1046"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1070"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1111"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1171"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1204"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1297"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="52"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="701"/>
            <end position="942"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8091733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1326" mass="147086" checksum="F084823A1748A826" modified="2025-10-08" version="1">MATFQVSDSDSSASKVDHAGTGLARKQLTVTFEDVGIEVFGLGQDFGSNCLSVLGDLVPSFGKSNKSKRHILQGVSGQVCPGEMLLVLGRPGSGCTSLLKVLSNQRDEFQEVTGQVRYGNIGHEAAKQFRHQIVMNTEDVRRHPQLPAIGHTKDTMVGDEFVRGVSGGERKRVSLAEVMSTQAPLQCWDNSTRGLDASNALDFARVLRKSANEQRKTIIATLYQAGNGIYDCFDKVLVLAGEGREIYYGPAAEARAYFENMGFKCPPGANVADFLTSVAVHTERTIRPGFEGSVPNTAEEFEARFKSSETYRVMKSVATAKSSDSSLVAEIEDLKLAGQMEKIRTIGFLSREKSPYTASFPKQVWACSKRQFQILWGDRFTNGLQLASSIVMALVTGSLMYNLPGDSSSIFRRPGALFYPILLWGLNKMSETVASFMGRPIFTRHKRLGFNRPAAYAFACALTDVPFIVVMFSLFDIVYYFMVGYQHDVGRFFTQWLIYVLITLCFASLYRLIGAWCRHFGLAAQISGFMTMIMMVYAGYLIPIPNMHPWFRWIAYINPASYAFNAVMASEMGNRQMTCVEPQFVPFGPSYDSNQYRSCTTVGSAPGDDLINGAEYLYLQYDIHGWEIWRDVGILIAFWVFFATIAAIGFEVNLVSGAGSKVLYDRRSQQKELADSQDPEKTQAQGLPEQGDYAAAGSTVFTFKDISYFVHHEGKEKQLLQNVSGYVKPGQLVALMGSSGAGKTTLMDVLAQRKDSGRIDGSIMVNGKPQGISFQRTTGYCEQNDVHEPTATVFESLVFSARLRQDYSVPDADKITYVNQIMELLELTPLKHALVGVPGSGLSIEQRKRLTLATELVAKPSLLFLDEPTSGLDGQSAYEICRFMRKLAASGQTIICTIHQPSAALFEAFDVLLLLAKGGRTTYFGPTGQDSSIVLDYFSRNGAAAVPDVNPAEHIVDVVQGRFGTDIDWPEVWNASKERTEALAELERLDNGQTMEKSGITSETTPEPTEAETKDFATPVMYQVKLVTTRQSIALWRNPDYIWNKISLHVTNALFGGFTFWMIGNGSFELQLRLMAVFNFVFVAPGCINQLQPLFIKNRDLFETREKKSKAYHWLAFISAQLLSEIPVLIVCATVYFASKSGQVYLEMILYEFLYTAIGQAIAAYSPSEVFAALANPVFVGAGLINFCGVVVPYSQIQAFWRYWIYWLDPFTYLIGGLLEPVVWDVKVQCKPNELTRIPVPPNSTCGTYLADFLATSGGYVVDPDASNTCEYCAYTSGADYMRTMNINESYYGWRDVGITALFCISSYGLVFLMMKLRSKATKKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8S3</accession>
    <name>A0ABR1X8S3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673747.1">
        <property type="nucleotide sequence ID" value="XM_066806451.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039511"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="28574" checksum="50B229FBDF016BE6" modified="2025-10-08" version="1">MTGLVTGLDALSDILSKYRPKCFLQTQLLMHYLVPVASIAIIVLHRAKIRTKQKVSLGVFLCLNLFMVALAITRASKINGAAGVDVPWEFFWQFMEASVAVLMGSLTVFRTLLSSKSGSSDDQRHRPGVAVAPGDRPWPRARPAYYVFSSAGRRKRRAADATDADLEATRNNGGFLPEVPGATMTGLRTFIRRNNRTGDSTGNASAAQWTGVSSQQETVVDPDEGQQLMTHGLLKSNASHGSGARSYSQGQRGEGSPYASIERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X941</accession>
    <name>A0ABR1X941_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673865.1">
        <property type="nucleotide sequence ID" value="XM_066806569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039629"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="152" mass="17309" checksum="160D06C8E635DE89" modified="2025-10-08" version="1">MNRLVNQATAAVLDRAEPGYHDLRQELRYAVFEALAKNPATHHHAYIFTDSQTADLVGAGVCAERRSDLISVVLLCDEEAHLERVCAADRVARGEKLVDVPWVKMLREKTLIHRFNKFSAEVGSLEVDVTDVTPKERRRTGYFDISWMSVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9H3</accession>
    <name>A0ABR1X9H3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000036</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674124.1">
        <property type="nucleotide sequence ID" value="XM_066804351.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037411"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="375"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="55573" checksum="1D7B6D312584F86B" modified="2025-10-08" version="1">MMERRRPYGSTLCIPILRDDVYLVQSPKNVAEFFHNPKLAVSRPWSFVLGHCFGMSKTAVDAYLQDTSGTRPEPIPGSAPRSPQDRIAYMTHENFTSGLLQHGLNPATDCFRAELQEFFKSSLDIGHDWAYMPDITDFFRQYLGSAIIRTLFGKALLTMNPTFLQDIWEYDDRVMDLAKRYPRLWIPRTYRARDRLLSAITRWHTEANRAVEPTDESAWSDSVWGTKMMRDRYRALLGATGQDKASVASTNLALIWASISNVVPSTTTLAIQIFSDSSLLSSLRGSVSHLSPDLRPKELETIPLLLSAYAETMRFGVHIHVPRNAPHHNLQIQGVTIPRDKLIFVNTYLAHNDQVVWDTQSGRKPLNQFCADRFLVDPSDPSSGPTKKKPAATSENAEGEPQYSLEGLEGAWIPFGGGQQACPGRLLAKRIMLLSAALLIRDFDLELLIEGGKPDFHSPRFGFGVSKPTAPVPFRLRRRNHVCHPECPYYIDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9M2</accession>
    <name>A0ABR1X9M2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674168.1">
        <property type="nucleotide sequence ID" value="XM_066804395.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037455"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="172"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="34335" checksum="727F62A627E15415" modified="2025-10-08" version="1">MFLIVDPAERFPIVEPIEPGERIMENMENVKALDAIRFVPEDPDYENLIVEEHVIKKERWPKKMLYQAPPAPPAPSTAPGPSTGPSTGPSTGPATGGGQESGKGRGKGPGSGSQPSTAPPPHKSETELNIAKILRFRIDDVACEVCKEFGDQCEGDACYARYLRGPVRRFDRAVELREAGDMGLGLFLKDDLARPIRRQEMLGQYLGELVQASGRGSRIADYTYAFDLGGVATVDAREFVNYTRFANHHCKPNVGVKMAMIGRRQTILLQENRDLYPGERLFIHYGRGYFEGRRIFCLCDAIPMPHMPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9R5</accession>
    <name>A0ABR1X9R5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674090.1">
        <property type="nucleotide sequence ID" value="XM_066804317.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037377"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053221">
        <property type="entry name" value="Burnettramic_acid_biosynth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887">
        <property type="entry name" value="CHROMOSOME 21, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887:SF1">
        <property type="entry name" value="RAS MODIFICATION PROTEIN ERF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="23730" checksum="229DC02CC3E47D2C" modified="2025-10-08" version="1">MLRGQRNADGGRQQRAGPVGMLVRGLATGIGLATESYQYHKEKKASKTAAGNDAEEDAAGANGELGLEDEAHLSHQMDEAVWELDEAQDQLAGHEPDGEDQRGQLALPVVITQRRPGSRTRGFVHAYSPLLADVGIDQATFLHFLDNLNKSVEPSPWIQAINLASFAGHAVPEPFTMIISMAVKRVADASSELHSRSKTNKFLDQVNESFFAPEDWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA38</accession>
    <name>A0ABR1XA38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674295.1">
        <property type="nucleotide sequence ID" value="XM_066804522.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037582"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="181"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1329"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1037"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1356" mass="151897" checksum="98CDBD8D5C8B8F46" modified="2025-10-08" version="1">MSDSDSEALTPASTDLCNEIERSLLKTSSVFGGGASREFLPEDKLDLLLTESRVDAVLREQQVVPTPELIEFILSRAKRLFLTLLWIEHLKAIKKLQAAGFDDGALPVEKHEDQKGISSLNKNTWTLDSNATPLPVFKGWKRPKISNLVETQWRFLSVSFPVFKFYPLACEHRLPLLPCQSDERGRPSSGGFSSVYQLRLLGSPQGGQGHASSQAEYQVVAVKKFDDSLVGYFHKERKTIDKIYDIESHPHLIKPIAVFERGTDRCVLFPWAYGGNLSDFWRESDALLRNPDSRAELVSWCLGQMVGIADALRVLHHENCRHGDLKPENLLHFKDGDQRRGRLVVADFGLSKFHIAATARRDGPSSNWSRTHKYEAPEIDGAHRRGKPRSRDYDMWSMGCLFLEFAVWLVYGNGFLEGIRNPTLIVKYWQYNQDRKPEVHPLVRAEMAKILEHSRASSATKDIVQLVQDRLLVVKFPEPERDSDESDGDHPVRPSAEELLELMSEIQRRANSSSPYLKGRQIAPRTGMGDSLTVREKGHGRKDSGVHFSPGEEGDPEGPRIIVRAPTGDFGQETKPRKPTSHPQTYREEQTVDLNDRWGFSSDNDFARTLFQRTNWVPSAPTASTKTVPCGKCRKTDFFSPRSEIPFDQDELRVNAGNCDICAVIHEALFNLGWGERHGTIFRVGPEFRVASENETEPLVLSAYADPRTPTPDAERVAQVGYPNLPDMGSPQQFEIMRAWLDTCDHHHEGCYPWMRAEELPYMPTRVIDVGTLSKPVVRLVETSDMKTRARYVALSHCWGQLTDAEKFCTTRSTLNANKTHIPLDRLPKNFRDAVAVAREIGAQYLWIDSICIIQGDEADWKAEAQKMKDVFSSAYCTLAASSAESSIVGFLGPKDRETRKVAILKSPGGATMYLCRSIDNFHSHVEGSVLASRGVGFPGEGAFEEDDPFYIDAGVLGMRQRGPLRDTRKIAQCEISPHGRRPVPRLGPPLLQRRPHHPDAARVRHVLEAGLHALYRPRRRAAGPREPARRHVQDARRVRRPAGVPAAQPAMEAVGRAALAHRADEGWCVGPFVVVDGVPGAIDYVHVPMNDTDWFEENLESPFEGNKSLREEDGDGDGDHRATHFRVVASGLKVSRLWWKKGVTMDHGDDETPDVSSINRNFKCVVVGEQRTVGRKQRGRGDLGDKLQRRGKRHNTWVSFENPGLTGETAGKLLLNSKSLKLWRDFGSGCTIGGTFEHIKPFDFLVTSRFRGRTNVTYQLVKEIALQIGDMVFRPIGQPQRIGLPGRGALLGFIVAARVALADVRVHAVAPQRSAVAVPALVEVEVDGGRGGRQGEEAEKLHDEETVRIRRMDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAB2</accession>
    <name>A0ABR1XAB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000266</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674354.1">
        <property type="nucleotide sequence ID" value="XM_066804581.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037641"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF20">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14670)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="55"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8093581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="505" mass="55286" checksum="F57B88456729CB0C" modified="2025-10-08" version="1">MDPIEQEKADAATVEHRKPLDESSDEALFRQFASAGEEWHHLMTKKMLRKVDGHLLPVLVLMYLLNFLDRNNLSQARLGTLEADLGMTGTDFNLATSILFVGYLLMQLPSNLALTRVRPSLYLGIAMTVWGVISACQAATHSFGGLVAARFMLGFAEAPFFPGAVFLMSSWYTRSEMAHRIAWFYSGSSLANSFGGLIGAGVLGNLNGAHGIAGWRWLFIIEGSITVAAAVSSIFILPNYPATTKWLSREEQAYAQWRLIDDTGEADSAGASTLKEGVKLAFRDPRLYLFTLLQHASLLSQSFQYMFPAIVKTLGFGNVETLLITAPIWIGTFLVSLVVTYTSGRFRERSWHIIALMMVSVIGNVIVVSTLNTAVRFFAMFLMPMGAVAAYQIILAWVSNSFPRPLVKRSVCISFANMIGNCANIYGPYMYPASQGPRYLPGGAGTAAVALFTAFLALTVRVVLSRENRKLEARETIDSEGNVTTAGGTGNGDIDERAVGFRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAZ8</accession>
    <name>A0ABR1XAZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heme binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674525.1">
        <property type="nucleotide sequence ID" value="XM_066804752.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037812"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF76">
        <property type="entry name" value="CALCUTTA CUP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="114"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="274" mass="31110" checksum="CFBDF38623DCCBAB" modified="2025-10-08" version="1">MPETRGSVRQRKKAAQAAGEPVADPTPAESSATEEAEEVIPEPKPKRTPKARLQDEDEDLDGYTPWLDILRVITFLLLASAGLSYLISSGESFTWGMKHPPKYLRMNWWKSQFLTLEELAQFDGRNPESPVYLAINGTIYDVSANRRTYGPGGSYNIFAGVDASRGFVTGCFADDRTADLRGVEEMFLPVDDPVFDNKHYSDAQLAELKKLEREEAERKVFEALEHWANFFARSDKYHKVGTVKREPDWLEKEPRKKLCDAAQQQRPKRKVPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBC4</accession>
    <name>A0ABR1XBC4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 31 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000572</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674660.1">
        <property type="nucleotide sequence ID" value="XM_066804887.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037947"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06591">
        <property type="entry name" value="GH31_xylosidase_XylS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051816">
        <property type="entry name" value="Glycosyl_Hydrolase_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863:SF2">
        <property type="entry name" value="MALTASE-GLUCOAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="4">
        <location>
            <begin position="20"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="3">
        <location>
            <begin position="234"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="5">
        <location>
            <begin position="587"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="678" mass="77549" checksum="6F14D31C9734A18B" modified="2025-10-08" version="1">MLYEEDGRLVFRYDAEKLWIEPWGPNAFRIRATKAGTMPLRNWALDLPPPAAKATISISEQDKTASITNCNITAQISKLGKLTVHDVRSGKLLLEEYRRTRRDLLDPKCSSLEVNAREFQPITGGDYKVTARFESLDPRERIYGMGQYQQPYLDIKGSDLELAHRNSQASVPFALSSQGYGFLWNCPSVGRAVFGKNIMSFEASSSPILDYWVVAGNTPAEIVEAYAEVTGKVPMMPEYGLGFWQCKLRYQTQEELLGVAREYRKRNLPIDLIVIDFFHWPLQGEWKFDTTYWPDPGKFFGISYDAMIKELKELKIELMVSIWPTVDKRSENYDEMVEQGHLIRTERGIRTAMNFQGETVHFDATSPAARDYVWRKAKQNYHDRGIRVFWLDEAEPEYSVYDFDNYRYHAGPNVAVGNVYPRDYARAFYEGQTAAGQTNVVNLLRCAWAGSQRYGALVWSGDIASSWGSFRNQLAAGLNMGLAGLPWWTTDIGGFHGGDPNDPAFRELLVRWFQWGAFCPVMRLHGDREPQQPQHGTTGGAGCRSGAANEVWSFGDEAYEILKTYMNIREEMRDYTRELMKEAHEKGTPIMRPLFYDFPVDAKCWEVEQQYMFGAKYMCCPVMEPGKRKMTIYLPKLPEAGEGGDRWTLTRAETTWEGGQEVEVDCPLDYMPVFVRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBF8</accession>
    <name>A0ABR1XBF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxybenzoate polyprenyltransferase, mitochondrial</fullName>
            <shortName evidence="9">4-HB polyprenyltransferase</shortName>
            <ecNumber evidence="9">2.5.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Para-hydroxybenzoate--polyprenyltransferase</fullName>
            <shortName evidence="9">PHB:PPT</shortName>
            <shortName evidence="9">PHB:polyprenyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000644</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>an all-trans-polyprenyl diphosphate + 4-hydroxybenzoate = a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:44504"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="2.5.1.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.39" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674732.1">
        <property type="nucleotide sequence ID" value="XM_066804959.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038019"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01635">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006370">
        <property type="entry name" value="HB_polyprenyltransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8093959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="342" mass="37513" checksum="8C33045526483038" modified="2025-10-08" version="1">MRSFYIWLGFWSESRPTAVSLLAPRHVIPFHASAKHLAVSVESPSSPEIPKPYSPPSSGLLSRLPASWVPYAELVRLDKPAGTYYLFFPCMFSTLLAAPMADPVTSPLTVIGTTALFFSGALIMRGAGCSINDLWDRNLDPQVARTRLRPIARGAITPFKALTFTGVQLLAGLGILLQFPWSCFWYATPSLLFVASYPLAKRVTYYPQFVLGLTFSWGAMMGFPALGVDLLANSAALTAAGFLYASNVAWTVLYDMIYAHMDIRDDAKAGIKSIALKHDAETKQVLSGLAVVQVNLKNVKDCWWWFVNGCWITGGAITAGMCVDYLIQYSSQGEESEKIAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC25</accession>
    <name>A0ABR1XC25_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antigenic thaumatin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674996.1">
        <property type="nucleotide sequence ID" value="XM_066805223.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038283"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006771">
        <property type="entry name" value="CetA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04681">
        <property type="entry name" value="Bys1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046892460" evidence="1">
        <location>
            <begin position="24"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="131" mass="14256" checksum="B9A141189063BD79" modified="2025-10-08" version="1">MQLSIRTIAFFTSFLASGNSVLAGVTRIENHCGFTVCATFQNINNDNIGVSLKCANNAGLSQPFQLEGTIKGGVAWYDLSAVDGDPFLNQRRVGYWPNTNCQIVCNPGDKGCEWPYQQTCPNPTDMVLALC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC40</accession>
    <name>A0ABR1XC40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674984.1">
        <property type="nucleotide sequence ID" value="XM_066805211.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038271"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="77" mass="7772" checksum="DC9663D77E2FADEE" modified="2025-10-08" version="1">MLRVVPAVVEIFEAEVEAGVADGATTAVTGDVIATSISETGAMVPTGTSGAVKGNAIGATETAFEADDPRLEEGRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC95</accession>
    <name>A0ABR1XC95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674992.1">
        <property type="nucleotide sequence ID" value="XM_066805219.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038279"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="478" mass="54710" checksum="1FB58DB6627E9FBB" modified="2025-10-08" version="1">MTEIPRTTTHEWKGDFLHKRSLCLDGENRSHFEIERDPEEDEDIMSVLSRAYEVEYDRWAYQIEPLQRECRSLWSLTEIVLGEGLRAMAHLQLVDYTRSSVYPYLTDPDAHSLAVLAATASLPQALSLLGFMADRLSRKPRFSIHVPPKGVAFFEMIFQLPFLVFRTVSLVDVSNGPSLEGRSSCTDLSFLAFDSDFDRRGARRTEYPPLCESTFSCFIHGWDVARWTAYGLFDTYFDKLDCKESATQYFEDSRASEPYFTGDPLTFAQEDLNMPVSCPRHYFLRVLESRMVRVRDEWGKVVSEVLEMVQVGKARCHVAFQPLRLGTPNSDVLSKAIEDWQHSFRQIEQWNIQTRDLLIRLMRALEKTVASWKAFGSKDIKYLYQEGSVANIGPDALQTLTSVEDLVSELDSFRNELHHQVEVFEKGSMQEPEQHIRDVRSVPDACGSNLAMTDILCPVSYNTGWQGGVNITGPTEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCD9</accession>
    <name>A0ABR1XCD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675078.1">
        <property type="nucleotide sequence ID" value="XM_066805305.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038365"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="152" mass="16437" checksum="46A289B94F4DC542" modified="2025-10-08" version="1">MAAASLLASQAAAKPEQIRAVQEPIFHYYLQAYPQDRSIPVMGPESSSEYFNIAGTIQSTNTSRYLSVGDDSTSYKTLTFANTTGSGSGTNVWALEGDTIITGQSSSWGRQLNFLVCKLDGNFWQVYLQTGSATPSGKTCSNYQSLHLPCLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCY1</accession>
    <name>A0ABR1XCY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001169</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675257.1">
        <property type="nucleotide sequence ID" value="XM_066805484.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038544"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06105">
        <property type="entry name" value="ScCit1-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="467" mass="51712" checksum="84EFFF33744FDE1C" modified="2025-10-08" version="1">MAAALRLGSAALRASTRAPTFTARHAAFTAARCYSSKTQTLKERFAELLPEKIEEIKTLRKEHGSKVIDKVTLDQVYGGARGIKALVWEGSVLDSEEGIRFRGKTIPECQELLPKAPGGKEPLPEGLFWLLLTGEVPTEQQVRDLSAEWAARSDIPKFVEELIDRCPTDLHPMAQFSLAVTALEHTSSFAKAYAKGMNKKDYWGYTFEDSMDLIAKLPTIAARIYQNVFKGGKKDKDYSFNFANQLGFGENADFIELMRLYLTIHTDHEGGNVSAHTTHLVGSALSSPFLSLSAGLNGLAGPLHGLANQEVLNWLTEMKKSVGDDLSDKAITDYLWSTLNSGRVVPGYGHAVLRKTDPRYMAQRVFAQEKMPNDPMFQLVSQVYKIAPKVLTEHGKTKNPYPNVDAHSGVLLQYYGLTEANYYTVLFGVSRAIGVLPQLIIDRAVGAPIERPKSFSTEKWIELAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCY4</accession>
    <name>A0ABR1XCY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7598 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001209</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675297.1">
        <property type="nucleotide sequence ID" value="XM_066805524.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038584"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056019">
        <property type="entry name" value="DUF7598"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24535">
        <property type="entry name" value="DUF7598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7598" evidence="3">
        <location>
            <begin position="14"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="291" mass="32610" checksum="321031D6A97F6666" modified="2025-10-08" version="1">MFNVNNSSSVKGSAYIILNVIRSLNILVLLLIAASSVILMIPAKMPDGFTFFNDVALFFMLVICIFLAVSELPSFKAIGFVRAWYTRNWPAVGPNRGLKWFGLAMVILGCHTLGRLSDPRNGLDHMDLPFWRLCLAGGILAITFGFVNIITSWLYSGEGGLNARELRSKGAVTETAYYNSGKSDTYDTYSEDYESHRSDSVRKEKSRSWWPKSNKKPKISRPMPYEPDLEKGEEVVDDPVPSRSSPVIPGLQRPPSALHPIHGRQPSHPDHKRRPSSRYSLASNVDQFSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDB4</accession>
    <name>A0ABR1XDB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675385.1">
        <property type="nucleotide sequence ID" value="XM_066805612.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038672"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="57129" checksum="C7E9008EC9034A3E" modified="2025-10-08" version="1">MWADDEYVIQLVQEWQNEAFEGILRELRSIMEQKVKVKDLRPLKIQLKKAARWVLAEGYRGLDILAQKDADDVVGDGDKPWEERFGDYLQFMAVPLEQLDLSDQADADNKSFLRPRGKLVPTFLKGKCGRWQRAEEYMSLIRQQLTPPHSNSASPTVPSAPVAPANYVQPQVLQPMMPPVQEHQPILMGQANAPITTIPEQPAFQATGVQNEAVNEVQLVQTLSAATYGQPAPPIIDLALLSAGGEPTLPITIDDPMDLGDGTNNQGSWPQNPAPEFTSSGSGEPSFPCNEGPQSAGIDEELLSQADLLAEFTTLQDPAEPMDDDSDSASRFGDNELAEGDQPVHDETNDTVMTDNFSVPSIPPEEPTEAVSDCDSLSGGENEGPDAEFTAPQDPEDPMDVVSDCESDNEETNDTIMEDNASEQLTPEELQLTADFHAMIGGEGESSGEDESSEEDESSEENEVPELEEDEEDEEVDDDDYLSGGELAKRIACLQEEQAMLTGRMEARAKASVEEEEISEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDC4</accession>
    <name>A0ABR1XDC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_001386</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675474.1">
        <property type="nucleotide sequence ID" value="XM_066805701.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038761"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="10">
        <location>
            <begin position="148"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="481"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8094701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="561" mass="61236" checksum="BF3F6F542617C394" modified="2025-10-08" version="1">MPHSTTSGSFSRDQSVSRASAKSAGPDSNNDSGLEKFPDHIDSPMYNGSGTSVSPIPGLNIYSNGINGTTTQPPSGDRWLPKREPRKSIQWGQLGQPAPSAAYGLGQTRQTRQKSISEAFRGIRDRNGSVSQNAQDLAGALRAPLSYKLIILCVMWYTSSALTNTSSKSILNAFDKPATLTLIQFFLVAFYCLTSSYLASVFPSLRTSIPALKYPIRKPSRDVVMTTLPLAAFQIGGHLLSAAATSKIPVSLVHTVKGLSPLFTVFAYRFIFDIRYPRATYYSLIPLTMGVMLACSGKHKFGGELLGLIYAFLATIIFVTQNIFSKRLFNEASKAEADGQSAKSRKLDKLNLLCYSSGMAFVLTTPIWFWSEGTGLIGDFFTDGALDLTDKPNAMDHGRLFLEFLFNGTFHFGQNILAFVLLSLVSPVTYSVASLLKRVFVIVVAIIWFRNSTTNLQAVGIGLTFLGLYLYDRSSESNKADRRARMLSQSGEKDRPLLPLNTKGASTTQGMNPMYESPAAIANGHSPYPYTNGHTALNNGVGDDTKEERWPAAGKPPTRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDK7</accession>
    <name>A0ABR1XDK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Orc1-like AAA ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_001396</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675484.1">
        <property type="nucleotide sequence ID" value="XM_066805711.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038771"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020796">
        <property type="entry name" value="ORC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047088">
        <property type="entry name" value="ORC5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048866">
        <property type="entry name" value="ORC5_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14630">
        <property type="entry name" value="ORC5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21639">
        <property type="entry name" value="ORC5_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="ORC5 lid" evidence="10">
        <location>
            <begin position="224"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 5 C-terminal" evidence="9">
        <location>
            <begin position="317"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8094711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="479" mass="52178" checksum="3D3C2087F82A7745" modified="2025-10-08" version="1">MGSLFQLPDELLATLLSTYPCREPQIRTLATLVYPLAAPCRNLIIHGTEATGKSAITASLLAALGSDDEVETNLGYAIVKSPECVTARHLFERTTAAVAHALQWPNPAGRCETLAALTVELSKMLKYVERGKGWRFVLVFDAIDRQKEAPPTLLPALARLSEIIPNLTTIFILTAPFPALLRTPSTPNLYFPSYTKAQYTTILSTTSTPPSLPNTIDQEALDLYARFVAAVYDSLAKPASRTLPRLQQACQALWPRFTAPIAAGTHKAREFSKLLIAARAYLQDESILAPPSAATTPTKPKPSKPLTKTTTDLSNLLPSTAKLLLLAAYLASHNAPRHDQTVFSTWHHGRRRRRGGRRSPGPRPKHRKIARKLLGPGVFVLERMVAIYAAVRREWIADHQKGSEGLVNKNNSVVDGDVGMAIATLASLRLLLRVGGGGAAASGSDMMDRGGRWRVGVGWEVIRGVGRSLGIEVEDWLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDR7</accession>
    <name>A0ABR1XDR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001393</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675481.1">
        <property type="nucleotide sequence ID" value="XM_066805708.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038768"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="4">
        <location>
            <begin position="426"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="71"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="277"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="525"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="566" mass="63231" checksum="4111F048C907BE9D" modified="2025-10-08" version="1">MMLSVVRRPGAIVSTSAVSIPRHRHRPQHVRGPQFYPRDLKKRVDEYVVGQERAKKTISSVIFNHYQGLRRRNHQEEVERKRQEKILRRNEARDRQAREKDSPSTHPVEGSLYNDSARHGFATDDFAEDEFPGHNDSVRHTHPESAWQQQQQQQQQHREQEADFYILEDTSRPQPVKIDKSNLLTLSKKINVPFTICDCNSFTQAGYIGQDVETCIERLLIEANYDIKACEHGIVVLDEFDKIAKRETMNGRDVGGEGVQQALLKLVEGTKVSVNVKDNRSSTSRSASPITTNYSGPGSTSSSSGPQSSPPQPGKVDQYTIDTSNILFVFCGAFVGLDKVILNRVAKPSMGFGSELRGRSSNSTSNENQPDLAPELFKHLPHRPANAADASILTALDLTTPEDLQGFGFIPELIGRLHNIVALSPLSRDDLLRILTEPRNSLVAQYTALFETYPSHLTFTRKSLKAIAARAERARTGARGLKMEMERVLAEAMFDAPMPYVLVTEAAVQGRDKVGYWGKDGRFEVERRVRDEDGPEDAPGGGGNDGRRVVSSHTFEEYREAGQSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE26</accession>
    <name>A0ABR1XE26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_001519</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675607.1">
        <property type="nucleotide sequence ID" value="XM_066805834.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038894"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_eS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014401">
        <property type="entry name" value="Ribosomal_eS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_eS6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002129">
        <property type="entry name" value="Ribosom_S6_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="239" mass="27417" checksum="01283E4AE22F825D" modified="2025-10-08" version="1">MKLNISYPANGSQKLIEIEDERKLRDFMEKRMGAEVPGDNLGDEFKGYIFRITGGNDKQGFPMKQGVMHPTRVRLLLSEGHSCYRPRRTGERKRKSVRGCIVGMDLSVLALSIVKQGDNDIPGVTDVVHPKRLGPKRATKIRRFFSLSKDDDVRKYVIRREVQPKGEGKKPYTKAPKIQRLVTPQRLQHKRHRVALKRRQAEKVKDEASEYAAILAKRVSEAKAQKAESRKRRASSMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEE5</accession>
    <name>A0ABR1XEE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001752</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675840.1">
        <property type="nucleotide sequence ID" value="XM_066806067.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039127"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053832">
        <property type="entry name" value="DUF6924"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21962">
        <property type="entry name" value="DUF6924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045201663" description="DUF6924 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6924" evidence="3">
        <location>
            <begin position="151"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8095067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="240" mass="27014" checksum="DFD2F5455D472D96" modified="2025-10-08" version="1">MNLALLENAILLEFLRSTSCIQAAKATTPVPIPRLVATRRKNEISQLHQVTHPSPNSSPVHQHRHAYRPDPTRERLPAIDPYKDLPENLLPFALYVHVPLPGGEEELARIEKACNSETERDEDDFAVRRAPLRHDPAGQPLRAALTQHLDHLAQTADRFSPFYFAAVVDEDWEEAGLIVVTMNDESEDENGNDGWRIDQLRVPVNDVGLVLVNLQISNVGWEEFKEQYEDGEGDNGGGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEK2</accession>
    <name>A0ABR1XEK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_001714</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675802.1">
        <property type="nucleotide sequence ID" value="XM_066806029.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039089"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF80">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="558"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8095029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="591" mass="64135" checksum="9660AE8CF1B96AB0" modified="2025-10-08" version="1">MPVLHQLDYLFAIGTIFAFLDAWNIDHFNEPGANDVANSWATSVGSRSVTLIQAMVLAAIMEFTGAVGVGARITDVIRTGIVETDQFVDNPGLLMLGMTCAVIGSSIWLTIATRIGLPVSTTHSILGGVIGMGVASLGADGVIWVKEGSGTAVINGGVVQVFLAWIIAPGIAGIFGAIMFLITKFGVMLRKDPVKMALFAIPIYFWLTASLICMLLLWKGGGYTINLTDSELIGTIIGAGAGFAVLASVFILPWIYRVVVLEDWQLRWYHIPQGPLLLRRGPVPPPPAEFGGPVQNYYEGHLTREELEAKRMAHRAPNGDEESASASPRTQAEKKVIDTALDTSETHSQDDHPMLKKGLVGPKPEGKWYTPPVAFWWVKKLLFNGVDRDVVSMQHKKDLLSGDLEETHARSAHYNNKAEFMYTFLQILTACAASFTHGANDVSNAIGPYSTIYQIWNEGEVPGKKSNVPVWILVFGGAGIAIGLWTYGYRIMSNLGNKLTLHSPSRGFSMELGSTITIIIATRLKLPVSTTQCITGAVVGVGLCNGDWRALNWRMIGWIYGGWIITLPCAGIISGCLMGFIINAPRWGLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ86</accession>
    <name>A0ABR1UQ86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660499.1">
        <property type="nucleotide sequence ID" value="XM_066819614.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052674"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8061079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="379" mass="43072" checksum="013B52A63B41227D" modified="2025-10-08" version="1">MEEDEGLREIHQVLHGYFENDTRQRFQLEGPIASGADSIAWGVQQSTCGQKGARHLDEEGEEIPEDDINPWNNGSNTTDHIENEKKWLKVLRWAKHVMNILEVPADPLNRRRSPLRRHGVENWIFIEWIQHGALHRLVRRARAENIEYLPNRMLWRFFMCPMAWPPEQPIGPPDGAFEIIRQTPPLKITHGDLHSENVMIGPFEPDSEYPEHDITPVLKMIDLGKMSGNEGANFDATKQNIRDIGNLMHELCTLLNPWERSDLYDGRQTTEYQPLTPANATSITSEAVGLLLPHPRNNNETPCPRLDPDLRLLVCRCLAIRPGSRPGLTELFQAVMEAIRVRDVAWYASQGAGYCNPATETDEGISGLLQLLLRDAGPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQN3</accession>
    <name>A0ABR1UQN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660645.1">
        <property type="nucleotide sequence ID" value="XM_066819760.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052820"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF48">
        <property type="entry name" value="PROTEIN VAPYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8061225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="463" mass="51843" checksum="E810A67232D51A54" modified="2025-10-08" version="1">MSFLSLPIEIFHEILVAVAQALGSSKAALRLRKVSWAWASAMVGAIYASGIIDREDMVYLWPQYIAYKASGPEPQQGWLRPLLMLRRAGERVVAFRGGCGHDTLRCCISEVCAVARISTPFYPGSIRERFGEPIHEDDMQLLQTLLAVAAYTNDVALARHLLSDIQCPLPLIGRDATEKPRALFDEPLVAAAVTGHDEVLRLFLDYKLQDADRWNVWLAKNMVLKGAVEGNHLSTVKLALSLEPDVRDPDGEKLTAVFFGCLEYANDVEIFDLLYARARHFLHRGLVPYYNDSPRFWTENCLPGLLCRAAKRGNVPLMRYLMELGATTPGLSGITTESPVRPMKDRLEGCVWCAARHGHAEAVEYLLDQGFPPGEAWKAAVKYGNPQTFEILFEFVDKQSPQFGHDVMQCLDVARERGHDAIVQMLLRSGWHLLSNFDQWRFKDPAASQGLATDTGDGQEWDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UR13</accession>
    <name>A0ABR1UR13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660537.1">
        <property type="nucleotide sequence ID" value="XM_066819652.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052712"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055481">
        <property type="entry name" value="DUF7053"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117:SF2">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23155">
        <property type="entry name" value="DUF7053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7053" evidence="1">
        <location>
            <begin position="5"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="148" mass="16392" checksum="EA387CFA10710164" modified="2025-10-08" version="1">MPSETTITTPIPTSVSRDAVLAALHDHDRYIRTTCPALINYVHISSNPATTPDSLPCEVYEVTDKRPIGQTTFRLTLTDLPGEGIDALIEGKAPTGSMTIKSRFRVLEGAPQNTLEERVAIDSNMLMNKMIKGNVEKSHPEQHQKFMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTC2</accession>
    <name>A0ABR1UTC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660782.1">
        <property type="nucleotide sequence ID" value="XM_066818594.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051654"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="9"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="139" mass="15629" checksum="DD894A352A03448A" modified="2025-10-08" version="1">MSIQNQATPPALTTLPPEILRNVGDNLGFWDLISLMKCCKKNRHLIVTFDHTDVKQWPESRALKFLNNSTSAQSIFAILDEDVTRLGPGILYYTFSTSDFAWDKALIQHLPKSHRAGSLINRTISACPDGQLMKDIIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTT7</accession>
    <name>A0ABR1UTT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytosolic Fe-S cluster assembly factor CFD1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_014435</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660937.1">
        <property type="nucleotide sequence ID" value="XM_066818749.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051809"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03039">
        <property type="entry name" value="NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028600">
        <property type="entry name" value="NUBP2/Cfd1_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF19">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="15"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8062338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="32040" checksum="FC008E9855E186DB" modified="2025-10-08" version="1">MSLSKVKHIILVLSGKGGVGKSSVTTQLALSLSLAGHSVGVLDVDLTGPSMPRMFNIEEAKVTQAPGGWLPVTVHEANAEAGVGELRCMSLGFLLKGRGDAVVWRGPKKTAMVRQFLSDVLWGDLDYLLIDTPPGTSDEHISLAETLLKDARPGQVAGAVVVTTPQAVATADVRKELNFCSKTGIPIIGVIENMAGFVCPNCAECTNIFSKGGGEVMAQEFSVRFLGAVPIDPQFVMLVESGARPVYPAGTMVNGKDISGANASTEQAAETSTRKDAALLADKYRGCSLEPLFNQITRDIVAAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUL5</accession>
    <name>A0ABR1UUL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661189.1">
        <property type="nucleotide sequence ID" value="XM_066819001.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052061"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047324947" evidence="1">
        <location>
            <begin position="21"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="459" mass="48470" checksum="7002B50DF6BABEE5" modified="2025-10-08" version="1">MYKTLALVPFLLLGGRVVEAKPCLTCTPDVCYQVAHNTDVPGQNPKEDCSAFMRTTVTPSARYATVTVTAVQTLGVTDSFTDTEIGTATQTDTATDTTAETSVATVVSEITETNTVAVTITETATRTTTGTETTTIVITSTEVPFFDPKDMKRSNVVDNPDLRRALGSLGKDLPPLRALPGRDSRRGLPISIISASAAAAVSVPAYAAGVCADDKAFSSACRCNGVRSTTITAEVPVTTLTVTDSEQVTQTTQANSTVSLATTVTQIRTVVVTEVVSQTLTVPVTSTIDQTNIDTALETTTTGVIQTTATTVTTVVPPGPTSGFLRAVGSRFDGNYVSISNSRLVTFKGRQDATYLNIDYYGILHDGGYYAINDNVNTSLLKFRGGGDSDFPNSYFVACVSGSGTGKLTCNRLRGDDVTGQVYFQQCDSEVNGQSDGVFVSSQKTLEGCTNFEFVLEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVJ2</accession>
    <name>A0ABR1UVJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CipC-like antibiotic response protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661553.1">
        <property type="nucleotide sequence ID" value="XM_066819365.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052425"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="114" mass="12894" checksum="91DB5047FE3C5EA8" modified="2025-10-08" version="1">MTSTATTSTPQKHESSFLHEAVAGGAAFEAMKLFEDRQRKNGEVVKHGFAKEMLAGLAAAEVDKLAETKGMDYLDREKAKHHAKKQAEHLYEQQHGQYDDYNPNQNARHETMDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVW4</accession>
    <name>A0ABR1UVW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Satratoxin biosynthesis SC1 cluster protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_015171</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661673.1">
        <property type="nucleotide sequence ID" value="XM_066819485.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052545"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="83"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="342"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="410"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="496"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="575"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="588"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="598"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="633"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="654"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8063074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="680" mass="73932" checksum="8BC39E78CA307270" modified="2025-10-08" version="1">MDGLQLPPPGVDMGSAGDSAGVPSSVGGGPGQGQALAGATACRRRTRRWTRPLFAMLPHNTSTWPIIAVSIICILVATTAVTLRVYTRQFILNRVGPDDFMAVAALAGITALGAITIIHTNFGLGTHIYDIAMDPLLIMDFFKSLELNKQQFFYLGVVVYNFTLVFVKLSLFLQYYRLVDQVPRYRPLFLGAGFVVMGWTIAMVFSMTFICVPVYAYWDKSVPHVCLSDPMMQLTNSVGNIVTDLILLLLPMPVLWRLNLPIRQKWGVIGIFSLGFITCIVSLLRVIFVFDHGPSSDITFEGTVITGWTIAEVTTGLLASSLITLRPLMSKIAPAAWRSSPTGKSTGATTTNGNNNSNANNNNKDLENNTNTNSEVGVSFPADKSGLANNEPPIQMHPVLSQKQEQQQQPLESTINNNDNRPDSAPESDGGLSRTSSEIELVVQKPDTTADRRKSRGRSRTATLNSAPEGRPLTHQGRSQSQRQQDYQRHRQSRSASYFQNNSLDYDSNTIGSDQMGMGMAGSKLGRAASTSTAATPRVPLGSQRSGLQGGPAALRDNQERRPHAATQSVDRVPSLHPSHSTSSYSTTPPPPPPPKSPWALAAAMPPQQAPSQRRPERDGSLPPPLPRGSRPPTTPLPETPQAPRPPFKQHAHSNSSSSMLSDVSYEVKVWAPKGINDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWJ0</accession>
    <name>A0ABR1UWJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_015134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661636.1">
        <property type="nucleotide sequence ID" value="XM_066819448.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052508"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="5">
        <location>
            <begin position="4"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="377"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8063037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="401" mass="45230" checksum="D8EE109A2EF135CB" modified="2025-10-08" version="1">MEDIQPYEITIPEPDLADLKVRLSRARLPDELEAAEWDLGAPLEDVRRLAKHWAAGFDWRKAEAELNRFQQFTTDVAADGFDPVKLHFIHQRSDDPDAIPLLFVHGWPGSIYEGTKLVDPLAKGGAGNHPSFHVVVPSLPNYGFSGGVSKRGFSIDQYAEVLNKLMLKLGYDQYVTQGGDWGWFISRALSRHYPQHVKATHLNLDVARQPGWLKHPLLALEHGVKPYSRAEREGFARSEWFLKEGSGYGAVQTTKPQTIGYALSDSPVALLAWVYEKLHDWTDSYPWTDDEILTWVSIYWFSTAGPAASVRIYYEFARVNRGEATRPHQITQEQMMDWQSVPVGLSHFPKDLIIRPSSWTRALGRVVFEKTHPDGGHFPAWERPEAPGPAGAVVKRAGSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWT5</accession>
    <name>A0ABR1UWT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="9">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_014396</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660898.1">
        <property type="nucleotide sequence ID" value="XM_066818710.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051770"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF101">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0274">FAD</keyword>
    <keyword evidence="4 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="10">
        <location>
            <begin position="49"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8062299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="292" mass="31558" checksum="C228DF83D6C47287" modified="2025-10-08" version="1">MAMFQGVRPSYMLGGVAAAGIGLTLLSRNLMSDASAATGAPRKIFPGGPAFLALPLESSEMVNHNTKRLRFKLPQPDSITGLPLESSLVTFAWPKGHWKPTGRPYTPITPSDEPGFFELLVKHYPGGGMSTHLHSLQPGDSLRFVVPLKGYAWTPNQHPHITLIAGGAGITPMFQMVQGILRDPQDSTRISLVFGVNSDADLLLKDEFDRFERQYPGRFQATYTVSRPGPGSPHREGYVTRELLKEVLPAGGSSKVFVCGPPGLEDALVGGKGKSPGILEQLGYGKDKVHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3P2</accession>
    <name>A0ABR1V3P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_012553</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662559.1">
        <property type="nucleotide sequence ID" value="XM_066816867.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049927"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050673">
        <property type="entry name" value="Mito_inner_translocase_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13172">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="13">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8065806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="91" mass="10301" checksum="78A995A85B00519A" modified="2025-10-08" version="1">MDPTGLGLNATESRELEQRLQKRQMKEFMGLFSNLVDHCFMSCVDDFTSKSLSTRETGCITRCVQKQMALSQRLSERFAEHNAAMGAQPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5Y6</accession>
    <name>A0ABR1V5Y6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663075.1">
        <property type="nucleotide sequence ID" value="XM_066817383.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050443"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="334" mass="37765" checksum="CC3C78C6DDADE36D" modified="2025-10-08" version="1">MPKASKFVKTERLPASSRQVPYPNMQVPLDRLEIAVRPAVANQQRIMPRPPIQPSPSASPAATPRPRAEMWTFISGILVTNEFGNPLRTPEDVARILYKFIVEPFKKMMPHVDDDSERSARKLSAQRAELVIDWVLMMSATWPYIDAVQPVRLNYLVGLFLRSGCIKREVLGRSIYKTLLGFQRGNRMDYAHKLAGFVMQIHKVNWKLLGIRNGSFWPGTPDELPDWVNLLLPHKDNSPEAQAQRERPWTDGKGLVNRVVSVLRNPHGNPFRDPAPTGATNPPTMQRPMPAPAPAPTPRQPHAQQPQHGPSQKPRMKTGARPRRQQLSRNLADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6G8</accession>
    <name>A0ABR1V6G8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663255.1">
        <property type="nucleotide sequence ID" value="XM_066817563.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050623"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="597"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="750" mass="84287" checksum="350602EDA0AA482B" modified="2025-10-08" version="1">MEYNLDELDANLSNNAETPLPKRPSLDRHRTTGGHSGGGGSRNYHTRRGSLMPPGVDTTATSTKSGLSGGSGGLRGGRRSRISDLNLFNFELRDLAQKVLLTDGDTHASYHEYAVYTPPAKDLDGPFRSPSIMANDDEAMRMFRGSIRDGHGLDDEGEFVEAPPGKPRLLGRVRQLIVDRRPLPVTQDSNSHQDGLFITPEDYASLELHASTLPTIGRVTSESSFWDACKETLYIVLSFSANPQPPYDFLSMAYNLKTRTTTALIRRSFDTRWHDDDALDEYEKRLEASRSLWAHPLVLPIVLLQVQFLRTEEEVVANNDEVLDLEAKVDDLTGSAKQRRRPFSKSQRRGSSSGNKSDSIPFSPLRRLSTFVEEKVTKRSHDPGCGNGRSSHQERNPALYGDDYVPPQTIHLMKEAHDVLKGAIKLLDTLRWMERAVKLLVTVGDELDAQIKKLRSRSSGNMGIRAQRTDGDDCDDEDELSHQWHEIRQYLESTWRLCTALETDRRMSELRCRAQIDIMAQEDNNLNARMAVASTRDSSSMKALAVITAIFLPGEYMGTLFGMSFFNWEYNTKGDAGLSEDATRLDVPHVVIMPLFWVYWCFTIPLTFFIVVLWRAWWVNQDRFFRRHLSIELSNERYWTSDGRPRDLETTFMQDFLSVFKRSGGGNTTNSSIVGEGAAASAAARKKWMEQQGLQSPGFQRRVMSTTTSASLKEGDGTDTTDDMDGARRRMKTRTISFAGPGARDPGSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6Z6</accession>
    <name>A0ABR1V6Z6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012571</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662577.1">
        <property type="nucleotide sequence ID" value="XM_066816885.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049945"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052775">
        <property type="entry name" value="IUN_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46190:SF1">
        <property type="entry name" value="SI:CH211-201H21.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46190">
        <property type="entry name" value="SI:CH211-201H21.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046270610" description="Inosine/uridine-preferring nucleoside hydrolase domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="60"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="411" mass="44246" checksum="2F2938B3AC90FC48" modified="2025-10-08" version="1">MYFSNLVLATTAVVAGVTGAAAAKAGQQQQRSVPGSGYMASNSSNSNSTAGNGDGKPRKMILDNDWAAVAFIPILQALDAGWDVVGIVGDTADSWALQTSMHGLAGLELGNLSECIPVHKGADYPLLNTPELFQVWSTLHGKLPWKTDRVFQEGAFAPENKTAEDLGGEPTSGDPRRLSKAAFAEGFPKGELAGEHAAAWMVEQVRAHPGEILIYSGGAFTNIALAVRMDPAFASLTRGLVVMGGYIDSVLLGAATGRTLLQADYVSDINLKIDPEAAKIALTADFPEITVVGNGANQVFPDQQFLDELVEVENPYTTLLHGHTDMTLPYWDETAMYAFLHPEHVKDSVSFYLDVDTAWSSPYYGNIIGYQEALKPKAQKLQKVNYILEVDGDDFKSSVKRAVQHPKKCPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V794</accession>
    <name>A0ABR1V794_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ilp is an apoptosis inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663803.1">
        <property type="nucleotide sequence ID" value="XM_066818111.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051171"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053267">
        <property type="entry name" value="Verrucosidin_biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42087">
        <property type="entry name" value="ILP IS AN APOPTOSIS INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42087:SF1">
        <property type="entry name" value="ILP IS AN APOPTOSIS INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="27703" checksum="27D254C637A885A6" modified="2025-10-08" version="1">MFHYPHAQPSPQPSGSGATAGARGGGGGPEMPPSSFFPMEENQNQFDILEWYPHFQSCVRYFLDHAQHSPPVQAVAAFINIQLPFQKTQNPVVTSRMSGGSPSAMPSPTSRASGKLPMPMASPNQPPAVVTLNPYIRRLVVTGFDFPAVLHGFFGDSWALGIGPMHEVERRNYLFAAKSASWLDVKAHYDMGEEQTIPFLRPLQNVTEKEIVSAESNWSEWLAMQDWMVGPRSPEVERNSPVQHIKMEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7C9</accession>
    <name>A0ABR1V7C9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662651.1">
        <property type="nucleotide sequence ID" value="XM_066816959.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050019"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="28107" checksum="D07D17B718FB35E6" modified="2025-10-08" version="1">MHESEAPEPLRKPEPIPPEVMRQHDYSGSTHQFPGPYTSAYYGPADTISRADYATMSSASHVGTQYPLHDDRPRSVCGIKRSTFILSLVLSFIVIGAAVGGAAGGSLAVQPPVFPLKTDFEALVLLVRRASACPSNSLETSGGSATSSYLSIPTSGVSVALDCQKLNGNTQAVVIGDETRLFKLTCGQDYHSRQSQDLMGLTSYTMESCLHACVAYNLARNSSECVAAVFIADVSYATDKYGGNCWIKNGTKDSDAALYRSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7E0</accession>
    <name>A0ABR1V7E0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013859</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663865.1">
        <property type="nucleotide sequence ID" value="XM_066818173.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051233"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="188"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="307"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="309"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8067112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="644" mass="70585" checksum="C241452648CD197E" modified="2025-10-08" version="1">MDSNVGSKSRRVKDTSISSNSTDEEEVLSVSSGATESHFSDGHDLAAGITRGEHRDLIIASLLEDHFRTLAAELYNSTATAGSQNYTRHSPEIQPLAKRLYDEATRRLSSNQILSSPAASENSRNTRAQYMAGLDSLTGAQALPTGLISQFRGLTVQPFQGLSILPNPSNDLQLLHQTSRRSHYSSSFQEVSLLGKGGFGKVYRCYSPLDQSTYAVKKIALSDRLWKIFCNGNYEKLNHILREAQALAKLDHPNVVRYHQAWFDEPEHYPVASNPQSSQGQIQTIDGRPDGPLLLDYRPAQLENNLDSLDGEADDAHDDDQSADCGIVFGEDTPSLGGGQVQHNPGPEWSEHSTDDLSETKSATNDSDIFTDDRSRSMNAGNPRQAPDANVHTLCIQMSLYPMTLAQYISRSSSRSGSPRHCFHLVPSLRILLSVLAGIRYIHSKGMVHRDIKPGNIFLSALESECIGGYCDIACGSCPTQEQKSGRWLNPRIGDFGLVTQLAHGEMPPLSREAYRESSDHESTGASKDVGTALYRPPKWDNLRNSGVHLDIFALGVVLVEMLCPFGTVMERADTLNGVQKGDRSYLSNVEKRLAEEGYGSEVKAKAVELVSGMVQVDPAKRLSAVEIDDLAHQVLVSCDRKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGY1</accession>
    <name>A0ABR1VGY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP-sulfurylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Sulfate adenylate transferase</fullName>
            <shortName evidence="7">SAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MET3</name>
        <name evidence="11" type="ORF">PG997_010673</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>sulfate + ATP + H(+) = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Allosterically inhibited by 3'-phosphoadenosine 5'-phosphosulfate (PAPS).</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homohexamer. Dimer of trimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The adenylyl-sulfate kinase (APS kinase) is non-functional. It is involved in allosteric regulation by PAPS. PAPS binding induces a large rotational rearrangement of domains lowering the substrate affinity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the C-terminal section; belongs to the APS kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the N-terminal section; belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664278.1">
        <property type="nucleotide sequence ID" value="XM_066814988.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048048"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00517">
        <property type="entry name" value="ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.10">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03106">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059117">
        <property type="entry name" value="APS_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027535">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050512">
        <property type="entry name" value="Sulf_AdTrans/APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002650">
        <property type="entry name" value="Sulphate_adenylyltransferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004040">
        <property type="entry name" value="PRK05537.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00339">
        <property type="entry name" value="sopT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700:SF1">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01583">
        <property type="entry name" value="APS_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-sulfurylase PUA-like" evidence="10">
        <location>
            <begin position="4"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Sulphate adenylyltransferase catalytic" evidence="9">
        <location>
            <begin position="212"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="APS kinase" evidence="8">
        <location>
            <begin position="414"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric regulation domain; adenylyl-sulfate kinase-like" evidence="7">
        <location>
            <begin position="414"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="216"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="310"/>
            <end position="313"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="453"/>
            <end position="456"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="534"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="site" description="Induces change in substrate recognition on ATP binding" evidence="7">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8070470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="592" mass="65635" checksum="8674DA288FFC9C21" modified="2025-10-08" version="1">MANPPHGGILKDLIARDAPRQSELAAEAEKLPAIVLSERQLCDLELILNGGFSPWKADLVEIIGFMNEADYNGVVKENRLADGALFSMPITLDVSQATIDEAGLKAGARVTLRDLRDDRNLAILTVEDVYKPDKALEAKEVFGGDEEHPAVDYLYKTAQEFYVGGKLEAINRLQHYDFVDLRCKSNDYLPLPDLPVIVLCGYTSTSSAGPGVVAFQTRNPMHRAHRELTVRAARSHGANVLIHPVVGLTKPGDIDHFTRVRVYKALLPRYPNGMGVLGLLPLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGKNSKGVDFYGPYDAQYAVEKYREELGIEVVPFQMMTYLPDSDEYAPVDTIPKETRTLNISGTELRSRLRSGREIPEWFSYPEVVKVLRESHPPRSQQGFTILLTGYQNSGKDAIGRALQVTLNQQGGRSVSLLLGETVRHELSSELGFSREDRSKNIQRIAFVAGELTRSGAAVIAAPIAPYEADRKSARELVEKYGDFYLVHVATPLEYCEKTDKRGIYAKARAGEVKGFTGVDDPYEAPAKPDLVVDFEKQTVRAIVHQIVLMLESRGLLDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH74</accession>
    <name>A0ABR1VH74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664377.1">
        <property type="nucleotide sequence ID" value="XM_066815087.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048147"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205">
        <property type="entry name" value="NB-ARC AND TPR DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205:SF1">
        <property type="entry name" value="ZU5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="487" mass="54693" checksum="8B10BF562F66E2DD" modified="2025-10-08" version="1">MSDTIGSGSGTSQTFGNSSVGSGGRLFQGIVKETSICTPSPTILIPFSRDADFVQRGEIMDRLHQRRAQSFSRTALVGLGGVGKSQLAIEYAYQVRERSPETWVFWIFADTARRFEMDFQNIATYARLPGQHSPRADVLQLVTNWLVSESSGEWVIILDNVDSADFMIDSTQSPHPNRPHLVSYLPSCEKGSILVTSRNKNATLKLVELRNIIQVDPMSQEEAVALAEKKLGKSDDKMKCLADSLEYVPLAIVQAAAYITRLASLCSVNQYLERFAQSDHDKASLLNFEGGQLRRDPEAKNSIIITWQLMFDHIHRTRPSAAHLLSYMSVFNSQLIVIDMLRPPVFQSQRPTVAKCCPLHNMCKSSKMGFSEEDILHLADCSLISTRPDGQWVQMHSLVQLATRRWLQAAGDRGFDLWQDYLFIVCTAYCRSVLIPPPCSLLGCLRTYAIPARKGNRFQQSMVLEWLKTSRTLHQPSQMTKSVSWHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH79</accession>
    <name>A0ABR1VH79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664411.1">
        <property type="nucleotide sequence ID" value="XM_066815121.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048181"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF8">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="400"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="607" mass="67824" checksum="A7236E9B38F8421C" modified="2025-10-08" version="1">MGSRETTNGANRTNGHDTYQCSDIPIHANRHLKVICIGAGASGLYLAYKLRKDFTDFTLDIFEKNPDIGGTWFENRYPGCACDAPAHNYTYSFEPKWDWSSNYAGSPEIFRYFSDFADKYDLRQYISFGHEVVGAQWDGDANEWIVDVREGGGGNTTRRRADFLINASGVLNKWKWPDIAEFDSFKGPKIHSAAWDESVELKGKRVGLIGNGAADHVTTFIRQPTYVVPQQGMGHHKYTPEEQQELRDDPEVHLKLRKETERAITAVFPVFVRGSIAQTKITDAMREAMKEKLTTGSDDLDLELRKLIPDFPFGCRRLTPGVGYLESLSKPNVTVARGGGVTRMTPEGCVTADGKEWPLDVLICATGFDTSFQPRFPLLGRGGRSMAEDWSEAALTEPKTTTTNGNGSTTTTPSEEGGRGPETYLSVAAHGYPNYFMFLGPNCPIGNGPIIILIELEGEYMAHFLNRWQKQGPGLASFEPKREAVADFMQHKDAFMDSRAVWSECESWYRSRATGRVTALWPGSVPHYMEALSEPRYDDYEVSYRTGANRFAYLGNGFSQTELDPEADTAFYIRNNDKEGSGIFRPMQCSRNAKDAGPMLESTWGVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHN8</accession>
    <name>A0ABR1VHN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pantothenate transporter liz1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010956</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664561.1">
        <property type="nucleotide sequence ID" value="XM_066815271.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048331"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF4">
        <property type="entry name" value="PANTOTHENATE TRANSPORTER FEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="39"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="469"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8070753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="501" mass="54806" checksum="FE8B374FE1891CA0" modified="2025-10-08" version="1">MSNEEKVAAAPGATVALDRVASVKSKEETKLVRKLDFYILTYACFSYFFNYLDRAAFANAYVAGLKESLSLTGADYNILLSLATAGLLVGQIPNSIIIQKVPPRIWFPSMVLLWAGLTMASAGCKTYGQLCAVRFLMGFAEASTYAGNIYVMGSKTSEIAKRTAMFTVSGQVGVMFAGAMMAAIYTTMDGHSGLAGWQWVFLIDGIITCPIALFGFLYFPDLPETTRAPYLNQMERNLALERLPPKSEDGHNIQVWSLTKRVLGQPTIYICCVFSLLSAALQAIPTQNLMLLYLKNQQKARHYTQAQVNTLPLGVQALGIVAELGAAFVIDRFPRHRVFVGLTLCALQAISAIVLLIPTMTLAGHFAAFYLAATAYSINPLLYGWINVIVARGGDDAARSVVIASMVASGFLLWTFWGVVLYPADDAPYWRNGYIALLCIIVALACWLFVVRWLDGYTARKYGTAEEPMVSGDMPKVQQVRGPADEENRDDKQASSDAKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIG9</accession>
    <name>A0ABR1VIG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664740.1">
        <property type="nucleotide sequence ID" value="XM_066815450.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048510"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00195">
        <property type="entry name" value="UBCc_UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049567">
        <property type="entry name" value="WDR59-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="379" mass="42488" checksum="0840D1A6F788FC4C" modified="2025-10-08" version="1">MPQSDPGNLYLYNTRRGEDEPRDHHADPVTIFAGHGSQKAKEFLWRGRGNITDDGIDNREFQLVSWGEDNELHLNRVDPGVLESVGHVKGGAAVKKLILTRKGATYKTFRSVDDNARRERRSATMSDPRPGSGGAQYRRSALTMGMQTQQQSRSGSLPSWRGPSMKAKTSVGKAANRSLDQLGWMKGITMSRKKSSTREVPQRKESKDSTMFGSGFHGHWEEPEPLQEEIVRISQQLPNVQWDKIDLTGLLLDASLKGPWGTDGETIYIKVRVDVPSSYPKTRAPKFLIEKSALMSEQTYKKIDQEVNQVAYRFAKKKQNCLEVAFTYLLGETDLSSSTNFFKNVKDFDDELDPLADESSSEDEADEIPAGGQRVCPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIY9</accession>
    <name>A0ABR1VIY9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664905.1">
        <property type="nucleotide sequence ID" value="XM_066815615.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048675"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="152" mass="16974" checksum="871D924865146B3F" modified="2025-10-08" version="1">MITNTEERSHAELKAMYQGCVGIIDGCACLTRSDYHEALEAADAAVELAEAARLDEETLQEFRELQARCVSLLQEEYRASEHHERGCYNKSTSAKQSSSTPSPFPAAAASPCHEDEEEETIARPSSRRRKSVTWFDQITVTGMLSQMTISRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJB5</accession>
    <name>A0ABR1VJB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_011541</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665146.1">
        <property type="nucleotide sequence ID" value="XM_066815856.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048916"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF161">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="51"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8071338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="372" mass="41268" checksum="62040DF736751BA5" modified="2025-10-08" version="1" fragment="single">MFLSPRLAIVGNDTTNHSAIHTNLIPPTEQGVRILVANAVLAVLTAVWTALRFWCRRMKGAGYFLEDWMHLGALVCFYGTVASNVLMVLVGGSGHHMSELQPWHIIRLSMAAYSTQVLYAISMALAKMSITWMLKRIFVTQRFALAARAVMAFTAAWTVMTILIGLFICRPVEMNWNPYTPGGSCGNQLAAFASVGVIDIVNEVSILVLPIPMIWRLQMPFRYKSALFCVFGAGILTSVFAAARLYNVIHLDFTDVSYSAVDANVYATVEPGVAIIVSCSPILRPLFDKVFGHKASSSNSKKSSGSSERVHRKLMTTLEMFGRSNRELKVRRREIWTSDGFTAMDGDADEPIRLSNFEANESRRCLQIEAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJN2</accession>
    <name>A0ABR1VJN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665264.1">
        <property type="nucleotide sequence ID" value="XM_066815974.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049034"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="147" mass="16510" checksum="0DA8F75D869B8C97" modified="2025-10-08" version="1">MSDLESDLFAINLSDDDHDPEAGASATATDPTTAPPVDRTGQTEEEFQAVRRGYRVKVENGDIWKTIKLPLAPKPKKHETQELLHAVEELYFFRRFEEGAAFARRALCEGQEEAKSEATLDADTRRLLKHYESRCRERSAAAAKTAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKF5</accession>
    <name>A0ABR1VKF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010918</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664523.1">
        <property type="nucleotide sequence ID" value="XM_066815233.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048293"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23953">
        <property type="entry name" value="zuotin_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.840">
        <property type="entry name" value="Ribosome-associated complex head domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032003">
        <property type="entry name" value="RAC_head"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042569">
        <property type="entry name" value="RAC_head_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054076">
        <property type="entry name" value="ZUO1-like_ZHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044634">
        <property type="entry name" value="Zuotin/DnaJC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058871">
        <property type="entry name" value="Zuotin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43999">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43999:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16717">
        <property type="entry name" value="RAC_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21884">
        <property type="entry name" value="ZUO1-like_ZHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26185">
        <property type="entry name" value="Zuotin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="101"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="242"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="296"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="306"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="444" mass="50626" checksum="BA185137C662115C" modified="2025-10-08" version="1">MASTTKVERPLPTLPEGWSAEKDFKPVGKTTGSTQRTIEPVGPHFLAHARRARHKRTFSEDDRIQAQEKAKNIEQNDDSDVSEPEDPMMLQREAKDWKSQDHYQVLGLSKYRYKATEDQIKRAHRKKVLKHHPDKKAASGRTEDDNFFKCIQKATEVLLDPVKRRQFDSVDEKADVEPPTKKEAQKNYLKSWGKVFKAEARFSKNPNVPMLGGDDATKPEVDEFYNFWYNFDSWRSFEYLDEDVPDDNENRGQKRHMERKNANARSKKKADDNARLRKLLDECAAGDERIKRFRKEANAAKNKKKADKEAAELKAKEDARLEKEAKEKAAKEAEEKAKTDREANKKAKEAAKNAVKKNKRVLKGSVKDANYFASGGEASADQVNTVLNDVEIVQSKVDPEEIAALAGKLNGLKVADEIKNVWTEEVKRLVEAGKLKDGEIKSMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKJ5</accession>
    <name>A0ABR1VKJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Endothiapepsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011610</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665215.1">
        <property type="nucleotide sequence ID" value="XM_066815925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048985"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06097">
        <property type="entry name" value="Aspergillopepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034163">
        <property type="entry name" value="Aspergillopepsin-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF2">
        <property type="entry name" value="ASPERGILLOPEPSIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046655365" evidence="5">
        <location>
            <begin position="21"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="93"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8071407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="409" mass="43833" checksum="286A0DECCFD8B616" modified="2025-10-08" version="1">MHFPTTTVLLTAGLAGLAAAAPAPTVPRTKVGTVSINQVRNPHFKHHGKRRGQRIMTALHIPFDMNGIHLGIGKRNGTQGSVAAVPEKDDIQYLTPVQIGTPPQTLNLDFDSGSSDLWVFSSETPSRQVNGQAQYDPTKSSTSEKIDGQTWSISYGDGSASSGIVFKDLVQVGEVSFPAQSVEVAQKVSSSFSSDENNDGLLGLAFSKINTVKPNRQTTFFDNVMGGLEKPIWTSDLKNDAPGTYNFGYIDEDAYTGEISYVPVDNSQGFWSFEASGYSIGNKSVPLKFQGIADTGTSLAMLPQEINTAYYSQVPGASMSYSLGGYVFPCDAKIPDFTYKVGDVSITIPASFINYAEADEEGTKCFGGIQPDTDIGFSIFGDVALKAAFVVFDAGTESTPRLGWANKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKX8</accession>
    <name>A0ABR1VKX8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664764.1">
        <property type="nucleotide sequence ID" value="XM_066815474.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048534"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="298" mass="32270" checksum="9721A13E3F07E619" modified="2025-10-08" version="1">MMIQMRTLKPRNYSEDANTETSPGSPRPLTRNSSPSPFVRERLSRSRQGNQLLPSPGSTQRQQQQMRVYREAFSSSRSSSRPASRRGSVGDTVSDGPFPTAAAACLAERMVACPVDSQDLPSPPSVPNANDDKKEEDEAAAEEGGNDQQQEEEPSATADSPQPPSPLITILSDDHCPSSSSSTSALSSSPPAEATDGETKTRLSPPLYLNESTMHNMTTAKALELFLDMPVLSTPQEFIRAVSWKRGPGDGGDSRAYVVVDEDGGGQGGPKWLRRIGSWRSAGEGSEDLELKDWKYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VM76</accession>
    <name>A0ABR1VM76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011232</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664837.1">
        <property type="nucleotide sequence ID" value="XM_066815547.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048607"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006846">
        <property type="entry name" value="Ribosomal_eS30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650:SF15">
        <property type="entry name" value="RIBOSOMAL PROTEIN S30, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04758">
        <property type="entry name" value="Ribosomal_S30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8071029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="63" mass="6945" checksum="7BFB0965B763679C" modified="2025-10-08" version="1">MGKVHGSLARAGKVKSQTPKVEKQEKKKTPKGRAKKRLVYTRRFVNVTLTGGKRKMNPNPGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU84</accession>
    <name>A0ABR1VU84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665717.1">
        <property type="nucleotide sequence ID" value="XM_066813755.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046815"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="179" mass="18424" checksum="AFE1829B4DE627B6" modified="2025-10-08" version="1">MLYETKTTRVAIPANFTANVTATTSGLSNIPTTADPTPTTISPGTSIGSGQPTSTSLDSGGGNRSQAWVSGPVIGSVAGVALIVAMAIFLLRRGKKARARANDEHGDKPQLHSDCVPKPELENSEKKAPVELPETDTVGATNELHELPGIRNPAELEAPNTTAQEQSGQLDTAAAGQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUT1</accession>
    <name>A0ABR1VUT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF914-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009674</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665951.1">
        <property type="nucleotide sequence ID" value="XM_066813989.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047049"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="40986" checksum="8B143B5447FB8B77" modified="2025-10-08" version="1">MDYDNKHASASGTTVTATAGSHDADENPEVIETAIHQIEAKRILALCITGTNTFSTLLVNKGTSIPAFQTLFNYVLLTLVYLSYTIYQYGFKKWGKVVLRDGWKYAILSFLDVEGNYFTVLAYRYTNLLSAQLLNFWSIVCVVIISFTLLKVRYKWAQILGILVACGGMGILLASDHIQGSNGGPGQNLLKGDLFGLAGATLYGLSNVFEEWFVSKRPVYEVLSFLGLFGIIINGATGAIFDRTTLIGSTWDGDVAGYLVGYTLVLFIFYSLAPLILRMGSAAFFDISLLTGNFWGTIIGIHVFGYAIHFMYPIAFVCIIIGLVVYFLAGSMLGDSKKPWLGDSQAEGVAGFGTAKLKALNLARKQGFAASEGDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV85</accession>
    <name>A0ABR1VV85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Het-C-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009824</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666101.1">
        <property type="nucleotide sequence ID" value="XM_066814139.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047199"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010816">
        <property type="entry name" value="Het-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052577">
        <property type="entry name" value="VWA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905">
        <property type="entry name" value="NG37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905:SF11">
        <property type="entry name" value="TINC (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07217">
        <property type="entry name" value="Het-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047128437" evidence="2">
        <location>
            <begin position="27"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="650"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="735"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="748"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="823"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="850"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="867"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="889" mass="97432" checksum="AEAE03C1B5412D11" modified="2025-10-08" version="1">MFTSKSFYPAVLAVVILCAFTPGALAFGAGNIAGISKVEGVNYGDLEDTLLTLAMARVLGNGKKFDKLTVQRDYSQAIDIGTVKAVSSEAIRLLLCVLGFMTFGFGSKEFEITAERLGTYRPEDHIDNPKGYGAGAGDPRQYDRRLRGPIDEDRELSIDPESGMKNYIANERAGIMTSAQHVRKLFGDSIELARSYRRSNNKDEIYEALRLLGTGLHCLEDFLAHSNYTELALIEMGERDVFPHVGRDTRMRLEGARDEVYPLVTGTFGGVDFLHSVTGEVSDKLTQNELDELEGTLTNNKNSNTSIIEDLLNKIPDGILGGDKKGEMQNIQDNAANSQMQNAQVSPRDPEEFTRYVQDIFKQVMPAIEFHDDLMKTIGEMIEKIPILPKILEQLEEQMSVWVFSIMAPFVVPVLKQVKNELRTGSHEIIESSEAEQHIVFDDDRSSDPTHSMLSKDHFSNILNEVAGKTASKVVAWATPQIMELWDDEGRNPDEVITNIIFGVMHHPAQRDQANGPSREGRQIMFDSVRQWWDEMDDRGRDDLRRKLSRDGNHKEGVHDTGHGCGKPLGMKKNYEGGEGGSMEDRIAGAAAGAIYEGITGGIGNVLEQQAGINLPSGEGGHPIQVEESGGHKSGIGGFLHSVGKSLLGDDFKKDDRESYSSRTDDDNSRTETRIEYGHSGGRYEQATESRTEYDNGDESRTYKRYEQDEDRRGNTTGYGYEERTESHPSYGGGRESHTERREDYGGSNQGYGGGNSGGYGGGESYGRGNSGGDSYGGGNSGYGGGNSSYGSGDSYGGGNSYGGGNSYGGGDSYGRESRDNESSSYGRQESSGGYGGGYGGGRRDEDEGGYGGRRNDGGYGGGESESYMRRGNNDYEERRDEYGSDRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVU1</accession>
    <name>A0ABR1VVU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666293.1">
        <property type="nucleotide sequence ID" value="XM_066814331.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047391"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF102">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="36616" checksum="FD873765A9E83990" modified="2025-10-08" version="1">MAQDESEESRSSTPKAQAPSYTRAKQVRPLDEEADGDTVADRYAFVAEDGRTYQGYMPGEYMLPNDSISPMRYTGSFLDNKLAAAPLRYPEKVLDIGTGTGLWALEFAEENPTSEVIGTDLSMIQPLPWTPNCQFVLENSETDDWLFPHRFDYVHLRGVLSCFHDVRTVIRRAHDHLAPGGWIEFQDGVFELAGHADGELDGTALQRWSALLRAGAAARGRDLAKARHYRQHLLDAGFVDVHERLVMVPGGPWHAADDKMRVVGVYIANIMSTGVVESFKPFLASAGLSPAEIEAISGEVRREMLDSSIRWSIPFCFLEVYVATEAYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWQ2</accession>
    <name>A0ABR1VWQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666599.1">
        <property type="nucleotide sequence ID" value="XM_066814637.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047697"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="164" mass="18192" checksum="DD30F7E4E3733284" modified="2025-10-08" version="1">MEVREIFNVTDANNDFPGKEEARRLLGAREGVGEAAKEIFGKAMDRCSTDPVIRSARQAKFEAAEARGERGLLVQLPEPFGVVSLEDSFQRLEEFMPEAVKPSSWPGETPTPSRRIRGFSSGTGRQEGLSCRSPFSDRKTQQQDKLETRMIPNMTDEVAPSSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX35</accession>
    <name>A0ABR1VX35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666734.1">
        <property type="nucleotide sequence ID" value="XM_066814772.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047832"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="85" mass="8832" checksum="02B818F8910DC60B" modified="2025-10-08" version="1">MELATPAVVTVNNIPKRATSTSSLLPVVAAPPTPAPAPTPTPISRRERFGRRVRQVKSKLSRGLRAILCSSSSSSSFSSPASTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX42</accession>
    <name>A0ABR1VX42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010467</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666744.1">
        <property type="nucleotide sequence ID" value="XM_066814782.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047842"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056693">
        <property type="entry name" value="DUF7791"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25053">
        <property type="entry name" value="DUF7791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="352"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7791" evidence="4">
        <location>
            <begin position="616"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="953"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="969"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="991"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1015" mass="115542" checksum="417669A60D249E80" modified="2025-10-08" version="1">MDPLSALAIAAAVVQFAEIGGKLMMKKWRRYKKQREPKPPNDESRWLREAEMEDALEEMTLFTRTIRESTDNVVSHVTPTAAEAQLLKLCEQCEETTGYFREVLAAAKQRSCQETTHKTELERLWTDDTTEMRQRDLHALQRRVTGIILLCIWENSKQTKKWEAEFGKKLNDVFSLLKRLEESTSRCTLPAVDANRLDWLLSSGDENDLGGNVHQNLSRGPDNGSSRNNPTPDLTSFFSQLVASDTTKISDAFKETLSRESMNLDQIYRELTGRLWRRDWQPEEDSVSETENRAMSAPDVADDLLELMTSGLRFETFTGRQEAIPDRFQSTYHWIFDRQPKKAPEGPPLWHSFPDWLEGASDPVYWITGKPGSGKSTMVKYIVESPATMGHLERWSGPLPILVVSYYAWIAGHGLQKSWVGLKRTMLHQAVTRQPELMSRVCPRRWALSQALPYNRRFPHWESWEVEESFNLLLTNCGHSFKLAIFIDGLDEFDIDPKEVVHLIEGISSVSTGCLKICVASRPWTQFDDAFSDVPMLQMHQLTKEDTVAFVAGQLDRNQGFREILDVYPTQVRELKQEIVAKARGVFLWVSVVVQSLLISFSEGESLLYDVIWARIEERNRRDGSWMIQVLAAAQGPLDCLTMWLADESRTTRADLEKLPVHFRDSAAVLLKRKLSARTRGILEIADASKEYVDFSHRTARDWVQQPAVWDKICASYGKDFDPNLVLFEAETLALSIPPRPRGARWAGMKKALWYASHSCERGMDDERLVQLMDFFDESIQENYVKATWPSLGARATGKQHWSMSQNRSLIHNGFMGLAAQFSILPYVRAKTANGRNLPSRKPTQDYTSLLDCAVFGYEFFTGYDVTESLNLPPISVERRFATVQFLVDAGSAPGPKFDVYLAQERERCGADSPVLLHYYNETEIKPQMSDASSMSQDPPHKPTAEIAKTHEAQTPPTGTAAHHQSHPSPSPRLGPPSLRPRTQHYHFRSFPSSYGTAVETNQRNAARTSPRPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYA4</accession>
    <name>A0ABR1VYA4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665839.1">
        <property type="nucleotide sequence ID" value="XM_066813877.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046937"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="331" mass="35805" checksum="1F44E361C1FE52CF" modified="2025-10-08" version="1">MGTPTKRADAASTLPRQAGPLTTIFTTPDFCAPGRWSATATPALSSSICMPPEFNRYYDYKYGFYSPGICPMGYTEGCAFPKTLAGRTNGTPFFGGTLMAGETARICCPTGYTCYTGSDEDKTYSQCIATAGPTTFLGYNYRSNTYLTTVTDALAYAIQVRWQSSDLPSLETDPTVPGSKYNGPMPTATDDATGVRQADGGRRVPGRFVARRERGQERLLARRRSEHGPGVAHDAPHGRLRQQHDGAGLGDGERDGRDDDQRTGPELASVDGARDARAGCRATEYLLRGRVARRHAAGGLDKDEPQYRVTCAATVELPERITDSGENEILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYD9</accession>
    <name>A0ABR1VYD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sorting nexin-4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Autophagy-related protein 24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_009531</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665808.1">
        <property type="nucleotide sequence ID" value="XM_066813846.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046906"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07628">
        <property type="entry name" value="BAR_Atg24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949:SF2">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="66"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8074868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="445" mass="49763" checksum="2A0A614C932E8E10" modified="2025-10-08" version="1">MAVIDQQDNFSSISWHSDQHDDDAGLAAASSPSPTYEHSRSDSSPANHPEIEGNPERLDPGLSGDILECAVSEPRKESDGTKDAFVSYLVTTSSTFPSFQKSQFSSRRRFTDFVFLYKTLSKDYPACAVPPLPDKQPLLIPPDAASDTATSADIPHLPRVPDWNATMKSRSARTSVGAEPGTGGVFDNFADTFINAFTKVNKADKRFIEVRERSDKLDDDLGHVEKVIARVVRRESDLETDLHDLAEQFQKLIVLEPGVESNVHAFAASIEDTAMGLRKLKDHTDQDYLGSLRDMSAYSIALKNLLKAREQKQLDHEQLTEYLNKSTLDRDSLASGYGSTGAGGFIRSKIEDVRGVDHEASRRERLRKLEIRIDELTTEAERAHKTSEMFDEEVVKEVVDFERIKRIELKRQFGGLAEAHVGFYTDTIDVWERYVKEMEGTVSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYW1</accession>
    <name>A0ABR1VYW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666049.1">
        <property type="nucleotide sequence ID" value="XM_066814087.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047147"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="138" mass="14672" checksum="C4C17955FE60CED4" modified="2025-10-08" version="1">MPPQTRIEPPNQIDSHVYMATEPIAVEPPAVYGVTHLAGTGLMQPLYGVPLGGDQDALEGGQLSGRIVVLGSSGGGAAGPYFDDDSKQQQHQAAKFIVADINTKSRLHCQAVTWSPRARESYVPALLDARPPLGRNDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZN2</accession>
    <name>A0ABR1VZN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010449</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666726.1">
        <property type="nucleotide sequence ID" value="XM_066814764.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047824"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03044">
        <property type="entry name" value="GST_N_EF1Bgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050802">
        <property type="entry name" value="EF-GSTs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986:SF10">
        <property type="entry name" value="ELONGATION FACTOR EEF-1B GAMMA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="2"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="91"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="222" mass="24328" checksum="0E0C6D137046743C" modified="2025-10-08" version="1">MAFGKIYSYPGNFRVQRAQVVAAINGLEVEVPADFQMESTKTPDFLSKFPMGKIPAFEGADGFCIAEGAAIAMYLAGSGPKAQQLLGSPTDLQKRARITEWICFAETELNPQVLPAFVMCVLKYMPYNEQTYTNAANNLERALKRVEKAVEGGKKFLVGEELTMADIMVAGPLFFGQGFLIDNKMREAAPGAIKYLDSLAEMPEFKSVFGEVKKCDTRVAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W0S5</accession>
    <name>A0ABR1W0S5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666724.1">
        <property type="nucleotide sequence ID" value="XM_066814762.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047822"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="217" mass="24547" checksum="8A2103719F20428D" modified="2025-10-08" version="1">MEMQDITVANITTPDGSDLEGLELPPGVSLGKRTERSTHSDTYQVLHHSNVVPFLEARVFDLAPEPAKVRKHRVRCIRRLETRKVLEETVGDLHVVVFVNDACVEDSPMLGDVADWLSSYASRVLTRYEDVLARQSHLGDLSVDSGSRHESTAQVGHEFDRQETYQELMGRAMLKLRDLLFRVVYAIAAWKVIFCFIGIAYLVFFGIGILGWLLMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8B2</accession>
    <name>A0ABR1W8B2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667195.1">
        <property type="nucleotide sequence ID" value="XM_066811853.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044913"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="37307" checksum="43E1F929BD3C4F21" modified="2025-10-08" version="1">MPTKTGSPFQTIPRNQIYCCICGGPFLEPSARDDESKDWLTRAVVLTTGHTTPDDATIKLDTFRSHPSVPFPELHPEHAQRRVLQFPAAYDERNGFPVVASGENAVAMDISMAGGHLYFPVHQLCYHLAQRFMDSQPVSRDTFQTQPGEEISSVKQLWEVLLHRMPSSRSQYILPEPHDYYGGAGCRNVYWEPDDGEPEYGELLEAAPMGMASITEDILKNLQPEAPEKPKAEIGINEEETVGYGQDWWCEALANKKPLPWLWDLDGELVREKKRNGGPWDWELLMRKLSRPEIHEPSDTTLNLPVGLRNRRRIWRCLEEARVGDTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9E0</accession>
    <name>A0ABR1W9E0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nicotianamine synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007911</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nicotianamine synthase (NAS)-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667568.1">
        <property type="nucleotide sequence ID" value="XM_066812226.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045286"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004298">
        <property type="entry name" value="Nicotian_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32266">
        <property type="entry name" value="NICOTIANAMINE SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32266:SF12">
        <property type="entry name" value="NICOTIANAMINE SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03059">
        <property type="entry name" value="NAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51142">
        <property type="entry name" value="NAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="33548" checksum="A9579C0CCE6016D5" modified="2025-10-08" version="1">MSRLLAWAGVSREKARDPPYSTIGRDREELLQELTDLRPSETTNTLFGDLVSQCCEIHDVNTVSQVLASCKLQAILPSLQSLCSQAESCLETHWASHIAQGQEPTEAQRLLETFPYYGNYEELTRLELCALRSAGLVHPQKIAFVGSGPLPLTPVCLLKALKEDALSGPVPPTKHQQGPTIINVDRDEEAVATATTLITRLGIPEEEMVHYCGSADSQSLSLSSCDVVYLAALVGVTQLEKEQIALSIAARMRPGALLVIRSSWGLRNCLYPEFDATTASLRSKLEVALVVHPYGKVVNSVIVTRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBJ2</accession>
    <name>A0ABR1WBJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA methylation modulator-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667867.1">
        <property type="nucleotide sequence ID" value="XM_066812525.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045585"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="460"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="221"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="360"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="489"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="419"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="509"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="554"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="590"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="632"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="658"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="677"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="754"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="831"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="883"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="946"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="966"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1011"/>
            <end position="1036"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1072" mass="113779" checksum="8A226A3D65E7B39C" modified="2025-10-08" version="1">MDALLSSIGQSVRAENNSNSNVCNRIEDVCHSLGKYVARRTDTRAEHISTSFEIRHNAVFDIVVEPEVAEGDDPVHHLQAPVTRSVNASETIMNQPSDDPVLQRMVAKHIIGAIGEVDGSSWNVRKVVRGAQGWDFTYQCKNSLQAWNRQNAKSTGRLPIAAWSGPGGQDPVNMGRPAFDCRGSVSILFSRTSRAIIIKYDHTPLHKTVAELADLLAPVVPPPPVPNGNHVGNKSTKAKRPPPAEGEEGAPKKKAKRKSKAADNTGAGEATTEETNTPAQNTSNPGQGSANDGAVSAMPFLKIPAAEAARRRELAVEMLSGKGIDPSTLSEEQMNIFSNQAPHLQKLSLEMLAKYGAERLRIVHPDEKDQPATSTNTTPAQGTPDVAAASAPGPAPATSGDTETPTKKSKGRKRKSDAAVESADGAAASRAVESGTAENGGMETTTMTLKPPSQRRTRGACDTCKNRKVKCTKEHPVCSVCQEAGETCVYLPPRPRRKSEKPAKSADNVDPDTDVQAEEEEDAGEPGQIEQAEQVEPPHIVHPVQITPVPVPRPMQAVQQAAPVAPAPVMDPDNDEFIPDPNILSGPIEQPQSAAPPSINTNYYSSNSGVTYSDADSSEAARHAHQAMANLTFPSSQFQRDTSQASPSLSFPSATQPSQPPPAYSQPPPVAQPPPARQNSRNMNRRSLPTGPVTQHQRTDSGNAAANMGRSPGWNNASNSPAAVAQDTTRSPHFSQAQAAKQRPKSRKSGYEAQAQSQSHAHPSPDTMQAAVTLSQTATQQQTPHVSAVTRSPFQTTRKPTARTQSRQGHRSQTNTPVTQTPVPPPQIPTSFNTPSSAYGHANNSTTSSGYDTYGRYNTSNAQYPNTTTAGDATAQSSYDANSYQPQATSTASSSYATPSYDYSRSSGTADANTTANDASNYGAANSSNSNQWASTQARGSRSDATHSYNMPNAQPTSTSPYGTRSAARQASQAAYSQSQQPGYSSYQSQNAAQSQQGQSNQTWYGFPAASASSSNHAGYNSNTANTTYGSTSASANAGAYSSHRPNVPGYGPSYGEEPSIFDLLSRGHSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBM7</accession>
    <name>A0ABR1WBM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008726</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668383.1">
        <property type="nucleotide sequence ID" value="XM_066813041.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046101"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046774713" evidence="2">
        <location>
            <begin position="18"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="127" mass="14146" checksum="083A11AA05B16DF4" modified="2025-10-08" version="1">MLFILFFALAIIPACIGFARYWGMGDEEGAIGLSTDADFMWLIAGNLLALLGNLFAILPLFKLTRGSLKYVLTQAGLWLSVALGGRVDRIVLLLEQVLELADVVLQQLFRYRRGVLLYPACWQSEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBP4</accession>
    <name>A0ABR1WBP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667038.1">
        <property type="nucleotide sequence ID" value="XM_066811696.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044756"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="105" mass="11849" checksum="8A85C3C83C26F7D9" modified="2025-10-08" version="1">MYMPAARPYTSKFLSLSYYNERTGKYGAGPSDLCFVGFCIVVCTGIRAALMQHVLVPLGWRWGASTKKDVTRFAEQGWVLAYYSAAWPLGMVFHPRQTNLTQFTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC60</accession>
    <name>A0ABR1WC60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX hydrolase domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668574.1">
        <property type="nucleotide sequence ID" value="XM_066813232.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046292"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051325">
        <property type="entry name" value="Nudix_hydrolase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340:SF0">
        <property type="entry name" value="BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340">
        <property type="entry name" value="DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="14"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8081099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="180" mass="20215" checksum="9E3E172FF7026772" modified="2025-10-08" version="1">MASSSTSKVYDGTQYVESCGAVVFDDSKQKVCLLLRARAKEDGSKQEAWVLPKGRRHCGEHRYAAALREVEEETGYAAHLQSLNMVTRAPAAQEPEAVTAGTPRPCRTYTEPFMVTHRNKEDGYLKLIYWYLAVADAQMTAGEETFTPRFFEPDEALETISFPDERKVLEKGIRLMTGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEH3</accession>
    <name>A0ABR1WEH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668376.1">
        <property type="nucleotide sequence ID" value="XM_066813034.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046094"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="200"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="473" mass="51950" checksum="92D271D558AB63D9" modified="2025-10-08" version="1">MNKLEALPFGPAVAASAQQQQQPAIDDDEAAFCYEPHVLCPACRALLTLAVARHRERGAQLSEYLATTYDFGRLCASARLGCHVCALFEAALWTRPRDIVDAAARMCDWTVALPVFSNDGGGAGVAGPGTAPRAGLSLGRSTGDEETFGVAKRWLSKCLEEHKLCAENDDAARVVRPKRLLQLEDTISLVDSTVAAGQEYVALSHCWGRQVLVPRLLKETEAELRAGVGLSYLPKTFQDAVLITKKLGFRFLWIDSLCIIQDSAEDWKDQAEIMALVYNNSVLTIAALKSSGSHEGCFTDARNPLRLRPCIVDELGVSVSSWNPGRLWEVEVNSSGYGASPLHSRAWVVQERYSAPRTLLYGANGIYWECRCAQASEAHYCDVAWDDEANKKTWLQRLEIGSTDDAQQHSNETTNKASAMVPWKDHWIGLLKTYSSCQLTQSTDKIIAVTGLIKEIERRSQGEASMHFGAVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WGB6</accession>
    <name>A0ABR1WGB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009032</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the polysaccharide monooxygenase AA13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668689.1">
        <property type="nucleotide sequence ID" value="XM_066813347.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046407"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045751665" description="Chitin-binding type-4 domain-containing protein" evidence="7">
        <location>
            <begin position="20"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="8">
        <location>
            <begin position="36"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8081214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="189" mass="20627" checksum="E73AF38C531E0BE4" modified="2025-10-08" version="1">MRAALATALGLLSAAGVSGHAVVETPTPRRTGPVQRDRCGAALTAQLEKDVASPIEDAMKKADEAYKCNAYLCRGYQLEDNLEGVQTVKAGDVLDFHIDLIAGHHPGYANVSVVDLATNQVIGEPLRSWADWPDSTSGPPRNDIDFNITLPDSLRSACDVAGKCAIQWYWWASKNRQTYESCVDFYLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WGC2</accession>
    <name>A0ABR1WGC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668613.1">
        <property type="nucleotide sequence ID" value="XM_066813271.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046331"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="103" mass="11030" checksum="98B840DB0924ADCE" modified="2025-10-08" version="1">MPGEPSGELRRMFNFGPSLVQFGPAPVDLGWTAENVGRHSGRTDRDWLAGRGTPVPDWRALEPLNPSCAASQILVLSARSEGPSDPPGVLARRPGEVEAKTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL61</accession>
    <name>A0ABR1WL61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="9">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_005526</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668764.1">
        <property type="nucleotide sequence ID" value="XM_066809841.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042901"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052247">
        <property type="entry name" value="Meiotic_Crossover_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47835:SF3">
        <property type="entry name" value="HELICASE FOR MEIOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47835">
        <property type="entry name" value="HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="292"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="506"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="181"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1194"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1227"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1265"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1289"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1312"/>
            <end position="1325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8084255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1417" mass="157445" checksum="544C5E425B723931" modified="2025-10-08" version="1">MSPNTRGGGDDTEAGRMYGFPSDRNDERRIQNFMNQTDNMFSTPARRIPQLTYDAIWPEDRDNAGANYFTNPFAVDDMMGFQHHQLDDFDRQVLGRPPVPPEYHFGRPAAESPRISLPNVNVPSSGQRRVLGDASHHFRPFAHRSEDYTPPFISNPLHAQPSPSTRPIFGRDVSHRVASLQPGTQLATPPFYRAQLPPPPEQHDYSSSSSELGKSSPSTRLSIRRQEPTTSSRPRPLSRPAHISLDLVHAPQHITPKIGDTYLLDPRKVLPDRCRAIFPYQLFNAVQSKSFPLAYGSNDNIVISAPTGSGKTAILEMAICKLVMTSGGENFKIVYQAPTKSLCSERARDWEKKFSHLSLHCAELTGDTSHAQTRRVGQASIIVTTPEKWDSITRKWSDHHRLLSMVRLVLIDEIHILNDARGATLEAVVSRMKTSGANVRFVGLSATVPNIEDIATWLGKDHSNQSEPATYECFGEELRPVKLKKYVYGYDSPGNDFIFDKMLDGKLTMLLGKHTEKKTIMVFCFTRKACETTASNLAEWWATCSADDKPWPSPKGRIPVISKDLQEIVRYGVAFHHAGLYADERASIEENFLSGQLHVICCTSTLAVGVNLPCHTVVLKGTVAYSDGMPQELSDLDVLQMLGRAGRPQFDKSATAIILTRREKVDRYEKMVSGKEKLESKLHLNLIEHLNSEVGLGTIQTLDTAKKWIDGTFLNVRMRQNPDKYTVKGGETGANADESLQQWCERDVRILQQHKLITQGNSFKCTEYGSAMSKYMVKFETMKLLLAIPKAPTMEQLLGGLAKASEFGDFRFKPLERTVYRKLNKDVQYPIQGSVNEPWHYVSISIQMHLGHVELPNDQEAGFLKKQMASEKLIIFDRLNRLVRCLVDCRVFDGDAVGVRSGLELVRAISAGTWENHPAQIQQIPGIGPVAMRKFQAQGVRTVLDLAKLSFDHIERIMSRNPPYGKNLCKVVEGFPQLTLRIEVLGAPGAYKKAGNSIGVVARAVLGHKNQKHPPSWSGKIPAVTFLAETSDGKNINGTDGLELKFPVSLSRPDEVVSCYFSCEEIVGTQVIDQVKVNTPASAFAALGAHVSPNPLPEAHVDYMTNNAVDDIDDEDMLEALDGAANSLSHSPHYDPFEEEDAGFPEIEGLIDDQEPVNPAPVQMKNGRWLCNHHCRGGGRTKNGKLCTHRCCKEGLEKPRPPPKRKSVEDSQPTNSTASRKKPKSQHNIEDGPKQKKKEKQDSHEDQIIELVDLSGLTDDDSDLDPAASAPEQAPSSKNRLPGLHRKAQGQNMKTPSRITKPHPFDLQYVLDDSDAIEEEEEEAEEAGHPPACHQDLAIDNQPPFSEDASVQLSSHDGLGEVDDTDQPFFLDPNPFDVAVNAEAESSQSKAPDWASELSPEVMDLIKGIVEVDGWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLM9</accession>
    <name>A0ABR1WLM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">O-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005717</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668955.1">
        <property type="nucleotide sequence ID" value="XM_066810032.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043092"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF17">
        <property type="entry name" value="O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005739">
        <property type="entry name" value="O-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="5">
        <location>
            <begin position="47"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="157"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="42056" checksum="9AD210E648D4ACE0" modified="2025-10-08" version="1">MAANQSPCSSDKILQTLESTSADSFASEGDRSKVLLAAHHLVARLETPLKVAKDLQLFEKWHERGGLAESATDLAALVNCDAQLLSRLLRHLASNQMLEEVSCEVYRPSPFAASLLQPAFGEWINYLYDISLPCFYKMPEYLEKTGYKEPADPRDGIHQYTWGHRTDLWQYHTDHPREGQSFNRALGGKMAHQAGWPDIVPLAPLLAGAEADGPLLVDVGGNIGHDLNKFRAVYPDVDARLYLQDIPAVIKGARVPDTVNKMVHDFFQPQPIKGARMYYMHGILHDWSDEPSRQILTALRGALRPGYSKLLIHDHVLPETGAQPLATSFDLMMMTCVSGKERSEGQWRDLLSSAGFKIVKFWRSPQAIQGVVEAELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLY4</accession>
    <name>A0ABR1WLY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Farnesylcysteine lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_005822</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prenylcysteine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669060.1">
        <property type="nucleotide sequence ID" value="XM_066810137.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043197"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010795">
        <property type="entry name" value="Prenylcys_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017046">
        <property type="entry name" value="Prenylcysteine_Oxase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944">
        <property type="entry name" value="FARNESYLCYSTEINE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944:SF0">
        <property type="entry name" value="PRENYLCYSTEINE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07156">
        <property type="entry name" value="Prenylcys_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036292">
        <property type="entry name" value="Prenylcysteine_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046387513" evidence="8">
        <location>
            <begin position="22"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Prenylcysteine lyase" evidence="9">
        <location>
            <begin position="137"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8084551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="560" mass="60744" checksum="1602AB7A40ED1793" modified="2025-10-08" version="1">MRLLSTLGALAAAAGVAPAFAADVTAKPVKQVAVIGAGAAGASTAYHLHRYAEEAGIAVNITIFERSSRVGGRTLTVNAHDNPLSPVELGASIFVRVNHILWNATDDFNLVRIDPGVDEKGLFGIWDGDSFVYTQDSESWGWWSLAKLFWKYGTAPYHVNNLVQQTVGTFLKLYEKPYFPFRSLTTRAFELDLVKVTGVTGTQFLAANKLDGPFAHDIVQAASRVNYMSNLAYIHGLGTMVSMAPEGAKSVLGGNWRIFTSMVESSKAYLNLNTTVVSIAQEEAKDTNEMISKYIIKTSNTSSAEAGKVVRQSVAFDDVVIATPWQFSDIKEEGDMIQHPIEPVPYAKLHVTLFSSPFRFSPQYFNLDPAAPVPNSVLTTLAGNDEAKPGSAGAGKAGFFSATQVKKVTNPKTSGEEYVYKIFSPEAVTSEFLSSLLGVKVPETFVRTSATDDGEDADFETIDPISWYHPAVFHPYPQKLPRVTFQDPILGRGLYYTSGIESFISTMETSALMGKNVARLIADDYLGISSTKEENVSAGLGHDREQVVLGGKQGVATDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM69</accession>
    <name>A0ABR1WM69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_005901</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.91"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669139.1">
        <property type="nucleotide sequence ID" value="XM_066810216.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043276"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539444" description="Glucanase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8084630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="454" mass="48543" checksum="28E3A10B8C46E623" modified="2025-10-08" version="1">MLSKIALLGGLLATTASAQQVGTQTSETHPKMSWQKCSSGGSCQTVSGEVTIDANWRWLHETSGTTNCYTGNEWDSSICSDAKSCSQKCAVDGADYSSTYGIQTSGNALTLKFVTEGEYSTNIGSRTYLMNGADKYQMFKLLGNEFTFDVDLSKLGCGLNGALYFVSMDEDGGKSRHSGNKAGAKYGTGYCDAQCPRDLKFIDGEANSDSWEPSSNDENAGVGARGSCCSEMDIWEANSISTAYTPHPCTEIGQKACQGDGCGGTYSSDRYAGDCDPDGCDFNSYRQGVKDFYGPGMTVDTNKKFTVVTQFIGSGSNLEAIRRYYVQGGKVIPNSESTIEGNGGNQIDETFCSTQKTAFGDTDDFKSKGGLQQMAKALAGDMVLVMSLWDDHYANMLWLDSSYPLDKDPSTPGVGRGSCETTSGVPADVEGKQGSSQVIYSNIKFGPINSTFTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM94</accession>
    <name>A0ABR1WM94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_005903</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669141.1">
        <property type="nucleotide sequence ID" value="XM_066810218.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043278"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053235">
        <property type="entry name" value="Ser_Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361">
        <property type="entry name" value="MITOGEN-ACTIVATED KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361:SF613">
        <property type="entry name" value="NUCLEAR RECEPTOR-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="24"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="409"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="409"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8084632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="461" mass="53225" checksum="C3A51F19EDAFBCF3" modified="2025-10-08" version="1">MEEAPYRGLSKRAASELSRQASKYDFASEVSPGIWKVVRKSDRAHFLARDVSSWLLDHGSDVPNHTSLLLLLDKQRMIEPLMAVLNHENLVNFIDWVQLIGWKDSKHPDQATHFFIYDYCNAGTLENLFQTETRIAPSGSEAPRIEVPVDCNRFLPESLCWHVLCSILKGLAWLHDGLREDLNPYTKEYEIFDAGLDWQTILHRDIAPSNIFFCHPHTMSETYGQCKLGNLSKAFVSGHVNGVLGDRVPHGQGEVLAGQNGFESLEKLRQNKDMPMYHPPQFNQPYTIISEYRSVGDVLMGMMIKPVMAAMKHMEYIRDRDEKSWNAIFSKASYSADLKDLVWELMSRTELEHQATFKLYLRAKEGFEDFRENDRDGKAMVTIDHVQVKHAEAMAERMASEAELMRRRNEQLDKEDEKVRDKELEAPSTNPTREKLLQEMAELCQTTVDRYQQRNRQVDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN12</accession>
    <name>A0ABR1WN12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669410.1">
        <property type="nucleotide sequence ID" value="XM_066810487.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043547"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF10">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="32"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="251" mass="27264" checksum="80A2984F95005B5A" modified="2025-10-08" version="1">MANNKPTVIIIGGGWHIPSSYSKLAGLLRWPALPNADLATDTQFIRSYVESLVEAGRSVIAVTHSYGGQLGTNALTGLGLETRAKSGLQGGVSHLIYMCASALLEGQTMVDKVKQFDHEHYMPVAFDFDAEDNTVVCRQPKATLIGDGQEGEADEAEIEAYLSNLVRWNGTCMYQPISHCAWREIPVSYIYTSGDGTLPLVYQESMVETLRKEGRDVATVELSTGHCPNLTKAKEVADVISKVARGEKLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN64</accession>
    <name>A0ABR1WN64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SPRY domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669372.1">
        <property type="nucleotide sequence ID" value="XM_066810449.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043509"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12909">
        <property type="entry name" value="SPRY_RanBP9_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035782">
        <property type="entry name" value="SPRY_RanBP9/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="3">
        <location>
            <begin position="192"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="CTLH" evidence="4">
        <location>
            <begin position="470"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="530"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="530"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="697" mass="77351" checksum="6D13DBA2F88BFD89" modified="2025-10-08" version="1">MSNPYAHGPAGLPLDASFTGYIPSMRSSYASITAATNPTSTPTSSTSQPRTNRLSHLLNPAHEMNSDLYPPRLSSMFQTHAMELERGSSTPDGDMSALGARVPQLPPFSRAFQKYMNGGTGDSLWASQYRPSAFFTPSYLKGSSYIQKLEEAHKAKQAQKEVQQQSGGGTHVSQIIPGSTHTKPVSHHGMTYDLIERAPLLEEDDSIAPLPTRWNRDDKHGGLEVMGDGQEVKYTGPKPVGEREHEACAIRADHPMPAEAGIYYFEVTILSRKRDDTTISVGFSHRPVSLARLPGWESDSYGYHGDDGHVYAGHQSGKVYGPTFGVGDTIGCGVNFKNGTAFFTKNGIHLGTACRDVKGPIYPAVGLKKQGEHIRVNFGHTPFNFDIDGLMQSERNKVKQEILGTSTDKLVSPSLSETDLIQRLVLQFLQHDGYVETARAFAEEIHGEKQALRLDPRTQVGGINVKDDEDATRRQRIRRAILGGDVDQALKYTKIYYPHVLEDNEQVHFRLRCCKFIEMVRKSAEFNNNNHRATNGSNSVIKKSNGRPRMDDIPNEMDLDENGFSNDDKMETEEGMDADALLLDAVQYGKRLQAEFMSDPRKEIRKTLQDVFSLLAYQNPFQVKEVAHLLDKRNRVAVAEELNSAILMSLGKSSRSALENLYGQTSVLLDYLREDGGSGSFVTVQSVMDEIPKSQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNG0</accession>
    <name>A0ABR1WNG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED6</name>
        <name evidence="10" type="ORF">PG997_006288</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669526.1">
        <property type="nucleotide sequence ID" value="XM_066810603.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043663"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.580">
        <property type="entry name" value="Mediator complex, subunit Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007018">
        <property type="entry name" value="Mediator_Med6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038566">
        <property type="entry name" value="Mediator_Med6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13104">
        <property type="entry name" value="MED-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04934">
        <property type="entry name" value="Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="149"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="204"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8085017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="31539" checksum="38687353882072B2" modified="2025-10-08" version="1">MVLRQLPFYDKTCNNAVLFQQAQFNITMVQYVESREALEGRLKTMSGLEFMVAEQPAVTGPGYGTGVWVIRKQTRRKQSNQDDIVEIHATYYVVGDNIIMAPTLADILTFRMTTISSYLSKCFPAADEATTWSPATGHEYRMPPAVTQTREQQTIASKEATPMPESQASKGLAEAKKPSQSTTLAPQLADQTWAIHMRFGGEYMDENPITGKPGDFHLSSTGRKEKLQPPVLNPLTIPAADSTNKSPASAPGDKPGKPGSGDKTPKTPTSGLSKPRRKKSKTGFTPTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNX8</accession>
    <name>A0ABR1WNX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Nucleoporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_006503</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin Nup133 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669741.1">
        <property type="nucleotide sequence ID" value="XM_066810818.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043878"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007187">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014908">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037624">
        <property type="entry name" value="Nup133-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13405">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13405:SF11">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03177">
        <property type="entry name" value="Nucleoporin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08801">
        <property type="entry name" value="Nucleoporin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like N-terminal" evidence="10">
        <location>
            <begin position="111"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like C-terminal" evidence="9">
        <location>
            <begin position="654"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1314"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8085232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1340" mass="150670" checksum="79CDD7A7580E210E" modified="2025-10-08" version="1">MFSPSLKNNPEHAPTPTVTTRGRRRQRPASSENTAQQPKAKRSRIALNEQTFVTPDASVENFEVKATRPQTKEPKQDGIENTPPPTIRKELSVRSKKAAKGSDRVGKGDGSRQHGSVDAATGFALSLTQTHAVVWPYTSLSHTPSDSFVFTLPYPSRYATDPLPIGSLVSSSVSSSETGLVVVMPTSGKVTYWESITSATTLDFMRQQRNGVEDTIPGMYSGETVTQIIRAESTTGFVLSFSSGRMAYLSVRDAHGRPQISVQLLRTSLAPKSGGIFGSIRNVLSQAAVQGDIAAVRSDRSSRQGERTVVAATSKGRLHAWKIHRGGHHDLLTEYDAKEAVIASIRERDLRSIAYPAETFRIHDFTYTPANPDEKYIDMTQLHHTPAYDTYQHLMLLTSFSDGDNYRYVLVEVLLPNGASPETPIVVGAIRPISSYSTPPNPHALAKPRLYLPKPAIVAFVVFDRAIIVTSIARQGDSPDSQLLEDSHILPATYEDVVDLRQDPVLEVVGSGIEEPHAFGQERTGQDENPSVVLLVRGVGTLRVLTSDIDKFPTDKAPEVTAKSKLEQAVFFGVKEDNPLVFDAQRELPFSDEEVGDAALELSNDILSSNSPHLTAGSVHLESHLRFRARMLEKLMSHLKNIKVSLNRVTRWKLLWNAEKLHAASYVWKKHEEFLNTRSAEAKKDLAAEIVEYIRTEEKHQPDVSRGEIDQLRYWFTHDTDRMNIFLAWAYEVIKYNSKAELDQPSLTRFICEAMQMNIYAIREAMEFRKRNLPLYGLEQEKMENGILAENYEGLPQPWTSDQYITNNLKRLVELASEWANQNYVTEVAGKTEQMLVQQIRTLLPALTEVYLTALQELSRSSLASSSAKTVTLGQSFEETYEKRPPREENWEAAVRLAEQHRSLAALAEIMIKETESLRTRLSTGALSPEETQRLEDRMKANEKQVEDYFAAYGQNFAFPFYDYLLSLDGIDAVLEYSGDKVYKTSFLRTKPELAKISWINDIIGEEDIVHAADTLLDLGLAREQQIWNKKIELSLGKLARMAEASRPASKASLSRQEASVNVTVADAGVDAIDKELSIIKIQDQLYGQVRPVVSVALDETAELPMALDAFPIKVPKKYKILSELYENGLARLLKHEALDPMTLIDLLTLIQLQPDLKEMISDQFFLAIQVANYALVDEEREQAERLIWRRLYLREDWTKINNTSHKDDNDVLEILGSTDLFSTFCVLHASQQSAEGKPYRRIMPSEALGVYTETLDRRFQKLDKGYGDRYLEAMRWEDSNLKKHVEKHRLEEWAQETRRLAEDTVNQQYDQQTVEGASQLSPTAAKTTTANGHSQNGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS28</accession>
    <name>A0ABR1WS28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Cutinase</fullName>
            <ecNumber evidence="3 10">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_006669</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cutinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="3 10"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669907.1">
        <property type="nucleotide sequence ID" value="XM_066810984.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044044"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043580">
        <property type="entry name" value="CUTINASE_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043579">
        <property type="entry name" value="CUTINASE_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF2">
        <property type="entry name" value="CUTINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00129">
        <property type="entry name" value="CUTINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00155">
        <property type="entry name" value="CUTINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00931">
        <property type="entry name" value="CUTINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 10" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044958499" description="Cutinase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8085398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="227" mass="23085" checksum="5D5030E040A866A2" modified="2025-10-08" version="1">MKFTASLMTAALAASVSAKPIENKSVVFDISEQDVAKAQAYEAEILATVGTTANEFLNGGCRDVVLVFARGTGQSGNMGDMPGPALANALKSALGDARVAAQGVAYSASLLGNLNSGGAPRQRGAVASQCPSSSIVISGYSQGAAMVHRAAEKLTAAARARVAAAVTFGDTQKAQDNARVPTIDAAKTRIFCNDGDRVCEGTLIITGAHSDYISSVAPAVSFITSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX89</accession>
    <name>A0ABR1WX89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002714</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670647.1">
        <property type="nucleotide sequence ID" value="XM_066807029.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040089"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="272" mass="28312" checksum="556F6BF1908EC3A9" modified="2025-10-08" version="1">MASLSLQNTTVLVTGAAGGLGKAIAAAYLDAGANVAICDIHEARLAETRAQFEGTGRFLALKTDITSEEAVEHLVAETVSRYGRLDILVNNAGMMDGFDPVGDLSKANWDKVLGVNLTGSFLCMKHAVRAFQAQQQSKIAGSDSDSGKFKGLVIQIGGNASTMGHQSGAAYTVSKHGVAALVKNTAAFYGDEGIYTVALMLGVMQTNISEGIGALGGFNQAAFARSSSATSSGENVTDTAYVARYCVFLADPRIAAGVNGSSITFNKNWPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXB3</accession>
    <name>A0ABR1WXB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670657.1">
        <property type="nucleotide sequence ID" value="XM_066807039.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040099"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="409" mass="44177" checksum="BD4C050496CEC274" modified="2025-10-08" version="1">MTTDPGSAPTKTTSRGAGPLTTVFHTPEFCAPDRWTEIGTPALSSSICMPDNWMQYFGNKAGMYSPGICPDGYTEGCALPTALPSVESDTPLYGGPLLAGETARMCCPTGYTCYTGPQTEPEKPYSRCISAAHSSRTYVESHVTHTSRNMAYLIQVRWQESDLSILETDPTMPGSTFSGPTATATATPNPGDDDGAGHMPFHIILAIAIALLLFLILLGIVAWLVWRRHFWKHQVIHRELASTPDLRKGGEAHFDHSAAGLASREEPTPLLDRPTPAYSRLTTSSYVVSPLTPATSEMEADMLPSIHEAPADAQPRMELEAREEVQELPAMSFAVELEGSTPADLIQPPPPRTPSRQQHQEEGAYSTSKSDGDAVGDEKSPGGATRRRKSLGTNRLTQANPPPPYSDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY99</accession>
    <name>A0ABR1WY99_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ML-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003083</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671016.1">
        <property type="nucleotide sequence ID" value="XM_066807398.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040458"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF6">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045440092" description="ML-like domain-containing protein" evidence="9">
        <location>
            <begin position="40"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="527"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="559"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="590"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="10">
        <location>
            <begin position="37"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="649"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="715"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="821"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="878"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="655"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="718"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="967" mass="104760" checksum="DB334136D761CB21" modified="2025-10-08" version="1">MHRYTPKRDGPKRNRPYLPAACQYALLLLALHCVQPASAVLLPFDNCLPSSYIASNNVDHAQLQWVPLYLDAVFDLENPTHNLRVTVYGNVTGTVGNTTLPLWNSTQWNGTGNVLNGKIQNQPDGPQGKATTLFSKVDVLSYEPYKTSSNFCNSTKNGPCPLGPVFNDTPIAYQNLPSIELRNDFASSYAFTSFAPTLIIWNGDARATSIGCISAVVTPSLGGISWFLRFLPVFVLLLVGVATVFAGVFSPWGTSDVFHWTTNYGRHPDLLRLVTPGFGDCLQYIQFIVLTGGLSLSYPGFYQPVVANGAWSALMFNQSFVSQAEPWTNVVDGVYITENITSVYDGSSIYGLESVSRLVGMSQVEDIWAGMMVWLLVIFAVLLSGIQLGFFFRWVFRYVRQNPEEDLRAKNMPFSMGNVIRLVFSYFLLPIVTLSLFQLVVAARSSVYLVALAVVTIALIVGFAAWLIYLIASTRPRSHLFDDLPTVLLYGPLYNTYSDEAAAFALIPVLLTFLRGIALGAVQASGIAQLVILAACEVVQMLTLHAFRPFHSPTSMNAYHTGFSALRFVTVILMVAFSPSMGVLEGPKGWIGYVILLIHGGVLVFGFFLNALQTIIEVVARMCGAGGDDSRGQTRGGLSRIFGARQLQRRMSRRGATSRQSQLSTTAMLDTAPASKRGYGRIRSGSAGSMGILLHPQQRSSSVLDGRSIDYSLPMGGSNFTPGTPGEVSNFSFLPSPGQATRPQPTADPYYRPPRARRPTNEDMGTPPSSQSPISFPDLPDADGSPSRGQTPAPPQAYTPVFAPRADYSTREVDFYYGVRGPALNSDGPGRKLGTGPADPTSPVSTATGWLKGLFGGKTKEKGKGFEVVRSARMPPAMKARGGDFADDGPPEGIPVAMGVLRNGPIESDDEDSSPRAKRGKRKDLLGDDGGGVTGRRRRGTGYWHNKGRGGTTSPAGSRCRRVFQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZG6</accession>
    <name>A0ABR1WZG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PIPK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671398.1">
        <property type="nucleotide sequence ID" value="XM_066807780.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040840"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF126">
        <property type="entry name" value="PIPK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="3">
        <location>
            <begin position="1"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="400" mass="44358" checksum="B5ECC2FE1CD1CF42" modified="2025-10-08" version="1">MGQRENQIAKSITYVIINNDEDGRPIQRQTVLGRIFSIFNLYWLTLQLVREDLFRSLREFWAIKPSDYKDSFTPASAASRNSGKAPMLQPMGDMGYSGSTFFRTPDGAYLVKSVPRSFEHNFFKNDMLLPYAVHMRANPGSLLIRITDFLECSRGSLGTLFGLAPSHHIVMENILYGQDEKKASSSTTSGGSGSGEEGAPKKWESWDLKPVSYFFPERDVAGGKLTSEATKSKLCDEFEGKLYLSLDQAEDFKAQLQKDTKFLSDCNAVDYSLFLVRTSTDDDAGADDDDDQEASSKAPVVPPAQPPFAPPGPPSWCTGVRSSNGKEVYRAAVLDFFWAKHTVHAKAMTGLINTGPMSVTAEADEYRQRFMKMCLDMIEVDGRMWNFEGAEAVGPESSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZT8</accession>
    <name>A0ABR1WZT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cwf15/Cwc15 cell cycle control protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671518.1">
        <property type="nucleotide sequence ID" value="XM_066807900.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040960"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="243" mass="28146" checksum="1FB61ABF9E86CB4D" modified="2025-10-08" version="1">MTTAHRPTFDPARGKEALRGPAYHQRLLPAHTQLKYRQPGQGGDADNEVRDLRAELLAAEAAHFAKANGGAPARALLRVRGGRRRQRRQAPPGAHIARRRREGGEDPEAKRRRILEESRDIDADDDDDEDDDDDDDDSEEDDSDDDEAELQRELEKIRREKAERREKEEAERAAAEEEERERDIALGNPLLNKQNFNMKRRWNDDVVFKNQARGTEDKGKKKEFVNDLLRSDFHKRFMGKYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X066</accession>
    <name>A0ABR1X066_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Tetratricopeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003783</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxisomal targeting signal receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671716.1">
        <property type="nucleotide sequence ID" value="XM_066808098.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041158"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024111">
        <property type="entry name" value="PEX5/PEX5L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130:SF0">
        <property type="entry name" value="GH08708P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="368"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="521"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="228"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="656" mass="72246" checksum="6C41E06080C1204A" modified="2025-10-08" version="1">MSFLGGGAECSTAGNPLSQFAKHTQDDKSLQRDRLVNGGPQGSMGGFRSTPNHAPQDEMMNGFLQQNGQLPAMPLEGMNQIRLDHPSQGVHLRANSTSPAWANEFQQNPQAAMESAFKVPQGTKFGPEDYTKFQHMMQQANSSRSSPMPQSMGGYQRPMGMGGMGMGMGMGMGGMGMMGGMGTSYGMQGAYGPQFQQPQPQHAMQDAKGKGKLVELDDSQWEEQFAQIALEDQRAREEEEQNKGIEAELNQMDERILESETNEFGDFESIWRGIQAEKAQAKENLDEDEWVSKFNEEDWQRNFANGWGDSSRLVGDPQIENYLFEEDNLFKDMANPFDEGMRIIDEGGNLSLAALAFEAAAQKNPSHVEAWVQLGTAQAQNEKETAAIRALEQAKKLDPNNLAALMTLAVSYTNEGFDSTAYRTLERWLSVKYPSIISPADLSQATDLGFTDRQILHDKITKLFIRAANLSPGGERMDPDVQVGLGVLFYGAEEYAKAVDCFSAALASAEQGASNQRSQVHLLWNRLGATLANSGKSEDAIAAYEKALTLRPNFVRARYNLGVSCINMGCHEEAAGHLLAALEMHKSVEKEGREKAREILGGGVSDSQLDAMTTQNRSTNLYDTLRRVFTQMNRRDLAEKVVAGMDPSVFRGDIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X118</accession>
    <name>A0ABR1X118_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Spt2 chromatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671963.1">
        <property type="nucleotide sequence ID" value="XM_066808345.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041405"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013256">
        <property type="entry name" value="Chromatin_SPT2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08243">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00784">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="205"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="352"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="388" mass="40699" checksum="C3BB0638E8D2B815" modified="2025-10-08" version="1">MPISDLLAEITGEKATANSTPSSIRTSTTLGLKRKADDDASSSAAIKTARTQQNGGPPRSSISRKPSPASGRAPNPTPKSSTSQPGQRSVSAAPATSKPYAGTATANRQAGGPPPARKDLAERPKLPSSTVGSSKIAPARPSPTTSTASEPSKAPKKGSFAEIMARGAKAQQVMPKAGIIQHKALQKPLPKKERETAKGGKRSGANGTTTKGSGQGGASQVKSPRALPKSGAVGDAKSGSKSRPTSSGSDAPEKKKKGPVMTGYAGTARSAPPMKKSTSSGKGAASRRPPGGGLLAPPKVARHDRYDDEYDEELDDFVVDDEDEDDPYARQYGYASDGSSDMEAGMDDIYDEESRAERAARLEDRREEQLLEELKRKKEEKKKRSGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X136</accession>
    <name>A0ABR1X136_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase-like 1</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Rotamase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004072</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672005.1">
        <property type="nucleotide sequence ID" value="XM_066808387.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041447"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="113"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="9">
        <location>
            <begin position="482"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="610" mass="68491" checksum="2ED491CC0CCC09BF" modified="2025-10-08" version="1">MAEVRDDEDSKSNKRSHSDFAGQAADDSSSDDDMGPQLPSAAPKKKRRVLPYEKLYISALPKSNRYSKSLMHKEHLSFVTVTPLTDFLVTSSVDGVVKFWKKVVDDIEFVKEFKAHQGEIKSVSVSQDGRSFATTGQDKTVKIFDVITFDLLAMLTVDYTPRCICWVHKRGASIPLLAIADDTAPLINIYDGRGENQTPIHTIKGLHRSVVAMMAFNDVYDCVVSADDNGMLEYWSPNSNYEKPENVFQYKSSTNLFDFKKAKSTPTSLTISPTGQQFVTFSMPDRKVRIFEFASAKLYRTYDESMQVIEEMQQAGTATQKLDDVEFGRRLAAEREIESPSLRNKANVIFDESGHFILYGSILGVKVINTFTNQVVKVYGKEENVRPVNLAIYQGQPQKKGVTTVAMAASNNPLLQESETRDPILVATAVGKVRFYMFTNQEEISKSARDVQNEKPTMLGCKEGGADEAGRDGYCSYFAYDAVENFVTHAKRGYYNNTVFHRVIRKFMIQGGDPLGDGTGGESIWGKEFEDEFSTLKHDKPYTVSMANAGPNTNGSQFFITTEKTPWLDNKHTIFGRAIQGLDVVHKIENVRTYKEKPEEDIKILNIDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X179</accession>
    <name>A0ABR1X179_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004142</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672075.1">
        <property type="nucleotide sequence ID" value="XM_066808457.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041517"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_A">
        <property type="entry name" value="Ribosomal_uS15_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_uS15_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012606">
        <property type="entry name" value="Ribosomal_uS15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006331">
        <property type="entry name" value="PRK08561.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15P/S13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885:SF6">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08069">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01386">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS15 N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="151" mass="16874" checksum="0A2955717C46E6BF" modified="2025-10-08" version="1">MGRLHSKGKGISSSATPYSRTAPAWLKTTPEQVVDQICKLAKRGATPSQIGVVLRDSHGIAQVRIVTGNKILRILKSQGLAPEMPEDLYMLIKKAVAVRKHLERNRKDKDSKFRLILIESRIHRLARYYKTVGVLPPTWKYESATASTLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1Y0</accession>
    <name>A0ABR1X1Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004376</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672309.1">
        <property type="nucleotide sequence ID" value="XM_066808691.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041751"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053025">
        <property type="entry name" value="Mito_ATP_Synthase-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44873">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44873:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="71"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="323" mass="35092" checksum="6132D666DD8C5C92" modified="2025-10-08" version="1">MPLRYIAALPTPALCPAPLIVFGARPTPTPNRLLTPSSSSSQARPKPRQQRQRPFHATTCLLDEEIDRATNHYEALKLPTNATPADIKRSFYSLSKSNHPDHNHSDPAASKRFMRISEAYTTLSSPEKRTRYDRDVLNLHHPARRAGSYSSTATTNPAGGRPASGLSKRRSAFRGPPPSFYRSGGWGAHSAKRSAAHESSTGGAGAGAGASSSSSQQGDHHNNGTATAGGMGPGQDPFKGSQDDVSHFDREGHERTGRRTEEARTSRRRMRTDGLDAIEAERGAMGMFFVIGGILLTSFLVPLGIYRVFWGSKTKDQKRKTKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2M3</accession>
    <name>A0ABR1X2M3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672491.1">
        <property type="nucleotide sequence ID" value="XM_066808873.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041933"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="206" mass="22297" checksum="ED04C159575BEAF5" modified="2025-10-08" version="1">MTPSPSPSPSLGQRALTTVPITPHLPVTDVFQLGPVPASLEASVVFSTEGVRDGYLGYGLERYVVDCPAARSPENDACRSLRLYPAEVYRDQSTIQGGVQTFRDAGVTMTWRCELREDAGDDSGVDDASTAVCDQTLIVAHSKTMEMTTITTSLDKCYIEQHFAPVVVTAGAEKLDVEWMNGDLPPAYILDWADELSSMGCPHGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2Q5</accession>
    <name>A0ABR1X2Q5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004575</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672508.1">
        <property type="nucleotide sequence ID" value="XM_066808890.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041950"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="9">
        <location>
            <begin position="90"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="388" mass="42446" checksum="06498F1C9800AFE8" modified="2025-10-08" version="1" fragment="single">PSRCRPLSPVTRTGSTLLVDGKPWKAVGPNVYWLGLDENVVPPEGEPYDPATKSSYPTKGRITDVLATVKALGGTMIRSHTLGISLGNPLSVMPAPGVLNEAAFASIDWAVYQAGQYGIRLMVPLIDNFDYYHGGKYTFLRWAGLNLTQSADANNPAIQQFYTNATIVAAFKDYIAQVATHRNPYTGRTYADDPAIFAYETGNELLGPVWGDMDCPADWVADIARFVRALAPQKLLVDGTYGVNQTHLDIEEVDIVSNHYYPVDTAKLQADLDLVEGARKAYFAGEYSWVGPDDAGTNNMTAFFDIIEKSTVAVGDAFWSLFGRNLPDCDSFVDHSDGFTLQYNNPANSEYTNSRIQLIRKHFVAMSQGTEIPSNEDLPAVPCPAPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X320</accession>
    <name>A0ABR1X320_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exocyst complex component protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004774</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672707.1">
        <property type="nucleotide sequence ID" value="XM_066809089.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042149"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048625">
        <property type="entry name" value="Sec10_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20667">
        <property type="entry name" value="Sec10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec10 N-terminal" evidence="7">
        <location>
            <begin position="58"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec10-like alpha-helical bundle" evidence="6">
        <location>
            <begin position="196"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="62"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="811" mass="90910" checksum="C03E01FC0DE82E65" modified="2025-10-08" version="1">MERNGSGSRALFPRGPSFTLDDFSNKDFIVRDFVDSLAESAVPANRRSGPANQQAFDPKPLIRTFENALQGLGNLSEELQQKESDLQSKVRRAEVQHDQTLDTLGLKLDQSIKQFEDLDISLNNPSTLDRSSRNDPSGGGNIAVQIGEKLEELDRKRRRALDANFLIQCWLEVGETGELTSLQEIQRQGGADNKVRCAVIAHQLMRISQRLDLAAWGQTNGNARGVANGVTGVFRSNYNTREVLEKFCETLEQELLKQFNNSYRKQNFDDMMECAKVLHDFNGGASVIAVFVNQHQFFIDRNQLITEEVAADGESFEQLADPDSDPPGLQSLIDEVKIIMQEESFIIKRAFPYYETVLIKFIQRIFQQSIQQRLEMVLEKADTISSLAFLRSLHSSRNYISALVEDLKAHGLTEHPDPCSAQIAQTLDQQMEELFVPYIVGNSYIEREKKSLEEMYNSLLFKYNIYHSRRKKAPTGFMASLAQQGSQLMASAKDAYLERLDSSDLTQTQKEMMLRVAGVQETDKNKNDIEVTDQDGVLSTANAKRMMTWLAESVRRTLELGSPSDTPKDVATLLNLLMTSMGQVYVETGLDAALEKATAQENSKTEPDLTYLPSIRPAVTIASIMSRFVTTVLIRLAEANTTVRRSMEAQSKMGIESIERKTNNIMKSTIDVLVNWVTKSLASQKKAIDGTNLEVFSSELGLSVQRLLIEHYKKYKINAAGGLMVTKDISKYVATLKEWNLNKDAESSVELLTEIGYLFIIGPEALRERSRNLATGPSGGSKKLAKADFKTYIQNREDYKSVGIQSVLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3X5</accession>
    <name>A0ABR1X3X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673008.1">
        <property type="nucleotide sequence ID" value="XM_066809390.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042450"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039970">
        <property type="entry name" value="TF_Grauzone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23225:SF2">
        <property type="entry name" value="AT09679P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23225">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="422"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="58770" checksum="5B90CDC805C0F7CF" modified="2025-10-08" version="1">MAYDTFSFSNTQAVYPSADHLVGEMIDPGLKYSNLAALEPTQWYPYSFPRALMAPNSTQYFTAPAYTGRQSDGMTTPIPSLPAPMHARQETPSEHSASSSDLSSGSSDHIPSTPPDEAAYPFQNHYDPWSAQSPSQMVEMTGMSDGVKLGDVNSLDDEVFQGFHEEKTTELPLRSYTMSSMGSSFEMDPMGHHEPIHFMRQTSPTAMTPHVKEEICIPNNYPPPEPEDDDNTSMDENEPVLQPIQDDEDDEDYKPKTYQRRGSNAKRSPPGSEAYPCSECHDVTFKDETGLQNHIKKQHTRPFTCLFAFAGCHSTFAAKNEWKRHVASQHLLLFYWLCSQGTCTKVSNSSSSSIRSPHAPNLPNGAIFNRKDLYTQHVRRMHVPLNIKKQLKQKNTVPEWEDSVQCFQKEAHKPRCSLPEYMTCPAAGCAHVFNGASAWDEHMEHLAKHLEKAASGIEQRIVFNGENHPTLVAWASRPDVAIIVPDRNGSWILNNPLSRRRTARPLALPDSMTMRTRMRRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4J2</accession>
    <name>A0ABR1X4J2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673229.1">
        <property type="nucleotide sequence ID" value="XM_066809611.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042671"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="319" mass="35978" checksum="6B9C8F52D5D30B32" modified="2025-10-08" version="1">MGITPSRVTRARTYVQRVSLTIIWLVELPPYLHMSPLLSASATGASPKKHQKRLERLRESHRYTGWSSIHCRINRDRPYWFFKGLAVWLLTSECLSHDESMTPIAFWSSYHVTGRPLTALEGAGSFYKGTITIYVEDRAVEFDISTYPQGTGRVESSGQPYTREWTHLGETARAHITGNVALTVYGLDMLHNDKPIIVFAPIDALRQAQTARDYQRAFCGVMPASSAWKWCPMQPPKTINMHGTWGREVEELVAILLGALVLRYAGGRPEPHGKQHGCNRSCQVGSQMSCSSFIGDILNEDDYLFRLVLKPTYETASKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4L7</accession>
    <name>A0ABR1X4L7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673196.1">
        <property type="nucleotide sequence ID" value="XM_066809578.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042638"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42749">
        <property type="entry name" value="CELL SHAPE-DETERMINING PROTEIN MREB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42749:SF1">
        <property type="entry name" value="CELL SHAPE-DETERMINING PROTEIN MREB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="469" mass="52416" checksum="ADBB4D1ECCAFA805" modified="2025-10-08" version="1">MDSELHLVVGIDVGASCTGVAFINLTKANADRSNVRTMSKWPGKTSESKVPTIMAYDSANVDQGPTSWGFQSKSESEQGNNRLLAEWFKCDFQSRSKDGSKLPDVDTLYRDFLSKLYGHLRERFLLPSTFGQGVTWDTAAVEFIFSVPATWRQHDVERFLAIARKAGFGSGSHRIGTCLTELQAVAVYAAYQEQNLLTAGDNVLIVDAGGGTVDFCLLEVKSIDTEYPELVEKLPVEGDDVGSANIDEKFQQLARIKLESLGHERLGLSSAKQIKTTAWRMRHSEDFQNEKVTLGAPPKAHAEEAFHVKMVGASVPTPGPGDEIYVANTDEMPFRYGELMGFFDEECQTIKRHMDQMIEDLQLHMQSDIQHVIFSGGLGGSPYIQETLRSQYGEGTSLEKAEFHSLDLPQMCVCKGLVIDRIEKMKRAKKENRTEVKNGQEVVPFVEWCIKRTYLQGVTYVLRSKYGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7K9</accession>
    <name>A0ABR1X7K9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673423.1">
        <property type="nucleotide sequence ID" value="XM_066806127.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039187"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046701172" evidence="2">
        <location>
            <begin position="21"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="28882" checksum="F78111C691180B68" modified="2025-10-08" version="1">MLSRTICAVLFFALSALVVGKNFGPPPLIRDEVTKPAASGRSAENNRAPGVRMTGHMSHHAPAGHRRDNEGTSNDLTDRDMLSHVPETHIFYRNFQINYSWTDERLLQALGARPKRGEEAASSKLLLDKRGSGGHALGKRSPPGGSPGNPIFKVSACLGCLQAQQGVVTSLDDLSTEYLEQQILLTDQQMLDRCVFYTSVPSWEEDRKERLKRRELGGEGQHTGLSKIATDWACRNNKVTIWVSSPIHCQGDGLTDRLPTTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7P9</accession>
    <name>A0ABR1X7P9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673416.1">
        <property type="nucleotide sequence ID" value="XM_066806120.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039180"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF2">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="462" mass="49536" checksum="F5C9943A9FE698E7" modified="2025-10-08" version="1">MTSAFKEDVHSGPSAPPSVHGARGAATTSANGEQQQEQQAGTSFLDGPGRDDSSTDDHVQDKAPPAAVLTKKQKFKRHCGRFKWWYVAGTIIFLAILLPILFLVILPAIVQRIVDDQGLPIKGGAFLCLSPTQMMISLETSLKTPLAARIDPLTMFLYNKETPEFSPFLNLTLPEQKLDGETAIVVTNRTVTITDEKELITWFDSVWDKPQTELSVRGDSTVHLGALHSKVHLEKTVEVNSLNQLSGFGIEDLSSSSRPSTTAATLTLGLGNVSLNLMAGDVRIGLITIYDVMIPPGNNTREFDGRLFLDQVAANLGTVLASQGEALNQGMIQIDATGNATVVNGKHIPFVEAILNKKRVTSKIGVFTLLGDVIDSLTNSQQAAGNGTATSGNGGSLVDLVGDTFGNSTLLSQALQHWKNATAQQQGGGGIESRATATPWWTRGPSSLHLLRLGMKMRMGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7W4</accession>
    <name>A0ABR1X7W4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673514.1">
        <property type="nucleotide sequence ID" value="XM_066806218.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039278"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="687" mass="76335" checksum="CC41957797C447BD" modified="2025-10-08" version="1">MSNNAPFYQTPASSSSVAGSVAGENDEWPVPQDAVEATAIADGELQPLFAQLSIMSGELKKPSTETEVADAWQDVFRFLPPEARRSLLLESPVRSLSQLSPETKQALLGTPKVRTSDDMPGPVLFGAGPGGSPDPPSEQQPVPAFPREPMTVYQGLGSVPPEILMVLHAYIPPLDELLLCHTHPSIFNNDRFSFYRVDAEYQVEWQQFNPRCEDERVPLLYHAISNDAPMSVITDILDSWQANGMDYDMAWAAGRVRTPPIMRPILFATGSGRVDVIQELRQRGASEQDLEHQVRLRAHSAQARARFTDETWWRMETLAIELCNRDVPTGAMRQLWLDACVCAGWKQLFRLFLELALGIAPLRASIRARASWWITGAGRVRRDSKAMFDFLFDRIGAQVMPPIEAQRGDDTFDDWLSSLIVGGANQPKRPLNAAHLLDRMRRQNSFHLLSLATTVPRYILECAADDACLPLTRALHDGLVDLTANYSYTFLTQAFGHDYTPARHPDILRAYMLHVALTSPQGAPQTVRWLACQGLVDLHLNMWELNRPHALQGLASSASAAVLQVNFDAILTRMPDPNAVVDEQVFPVRPVDLIHEHAATFVEFVARAPAHSDAGVGVDLTLASVGTKNAARERRELRESGMEIATMGRSLSQLMVEASISYEVRRRILDWCIVMGTNDVPAVIRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7Y6</accession>
    <name>A0ABR1X7Y6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001952</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673563.1">
        <property type="nucleotide sequence ID" value="XM_066806267.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039327"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="339"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="892"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="997"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="928"/>
            <end position="941"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1023" mass="111627" checksum="4A3BC90BC6A58125" modified="2025-10-08" version="1">MGHANQAPTDILKELCLIGDILGFVQLGTQLLTSPKELYGGKGFRRNERKDTITSPVGEEQKLACKAISQCRSYESRFCEGSLPLDLHAHTRECCYNSARRLRRYLERVRGRGGKSSKRGGTGGLRAALVKVWSKKEMKEQVQHLRQIRDLIEEDTFDSLIARITPSALEACPEFPWLKARHRELIIALSAGCSAPNPDDAKMTSTQVRTLCLSLSRSEANNALPQTLDRRPSVFSVTAPSSMSSRTAISTSTYLSASSYHNSTSSSSCSSLYSPPFESNITYKEARVWNQISEQLLSDLSAAVVPSATDKRPNVESDGAASYHDTYIEILQEESMSGLRSWLEERRDGHVYWVSGPRGSGKSTLMGSIAAYMCTRGLTIANEDELNLIVVKLTYSSRTDRRQEKDSWTAALYRSILEWSEAYCRSLGHVSPVASSVTATMMNWSFDRVKAVVDWLFTQEFIPFRACLLVDGLDEFSGITTDRSGTEDVDGLVRQIIAGKWSNAKCCISTQPSGALSAAFENRPSLQMAELTRPAMRKFAMDQLSSHAAVRAMRRCPDSKILLHQCAQEIADLADGVFLWTELAISTAMHELGGRAAGNRMHELRGRMRSLPRRLDGLYAYIIHTKQAVKGQDGVHSSRLFRLVAAASTPQEDDWTKPSPLSLLVLFFALEDDVAQRAIAAKTGFLEQHEVERCREAMALRLPRLSGGLIKVQGSGGDPARLMVTFINDAVAALAARSNKNTPSLRPPEPTDAATTDESPNLALLSAIVLSMKTKGVDITKSRGLRADVDAGILYARRAEAELGFDPILNRVTDELVEGAMATHPCWFQLNDTLSYAARCANPEEATAAAETPSPAVIVLVANHIAEAAFFLLLLSVASTPSARARQDRLYPAAIPNPPTPAWSGSGAFRQSGGGPDPARVRCRRVRSREAAGRVLDDPRQRQSPPATGMEKTAHAGPSDAEPYPPARHAGLGGGIRPTATLGDLVRDSWGCSLSGCQHPKWQGPKTGSCGPEKKGLVDIPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X823</accession>
    <name>A0ABR1X823_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673644.1">
        <property type="nucleotide sequence ID" value="XM_066806348.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039408"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02208">
        <property type="entry name" value="cupin_RmlC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="51"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="184" mass="20694" checksum="8901EB32BB886D6F" modified="2025-10-08" version="1">MREPKLLKELFIGKGLRMSLMCVEDEPVSSINRYYAEHVASGEEGDDVIDVPPHWHKIHGEYHIVLEGRLEITIDGKVIILKAGEPALYVPPKGVHSIRSFPGERMVAQERAEPPGTYKLEYFNDALSSGEFRDSKAHLVRALYDGDAYLPLAFGIKPVEEVLMWMLATVARLFAPAKPKLKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X833</accession>
    <name>A0ABR1X833_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001896</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673507.1">
        <property type="nucleotide sequence ID" value="XM_066806211.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039271"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06897">
        <property type="entry name" value="PX_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15858">
        <property type="entry name" value="SNARE_VAM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="2">
        <location>
            <begin position="295"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="305"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="358" mass="39277" checksum="E9F74BA107B908C8" modified="2025-10-08" version="1">MAPPAEITIPTTSLSKNDDGSKPYTLYNITLRLPLRTYVVQKRYNDFAALHQAIQTHVGTPPPAPLPAKSWFKSTISSPQLTEDRRRGLETYMRGIAESPDRRWRDTPAWRAFLNLPNSASNSAASVRAGGGFGIPNRDAARNAGAQDPGTWLDLHKEMKAEFQEARRCLSRRDNATDNATALEAGAAAKRSLVKASGYITSLGDGLRVIAESKRLGEGEIRRRKDLLAAARVDREDLDKLSSSIAPNMKAGALGSSGMPSASDKMALLGGAGDRPRASGRDAGARQPGVLQLRQQMMHEQDQDVESLTKIVQRQREIAEEINSEVARQNEMLEAVDDDVSRLDKKTNIAKKRVKNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8T9</accession>
    <name>A0ABR1X8T9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002206</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673817.1">
        <property type="nucleotide sequence ID" value="XM_066806521.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039581"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF57">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="42"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="290"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="302"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8091845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="377" mass="41444" checksum="DB05930709F7339A" modified="2025-10-08" version="1">MDTTPSNPNGGYESIPIQNAGQIWMIVTCVFTMFIPTALVAMRFVARSRFSNASLDASDWCIATALLFVLALCIVDFFMVFRGGFTFDLKDIAGRFGPDALDTFFRCMAAWPLLWNCCVLTSKLSVLAMYQTLMPIPRMKLAVRVVGGFVILYNVCGFITGLVICQPYEKNYDWAGVVKGKCGDVKLYYEWLSAINVVSDVIVLLLPLPFVYNLQLQLRKKIVLFAMFSVGFITCAVTIYRQTLLPSLDATNPTGTGLLAFLFSTVEIGVAVSLACVPFLRPLFRGTFGSSNRSHPSPESAYSYSKKGSGSSKPRSQGFNELGSDIQLSPVIIGNKSGAAAAATQQQSLNVQTSWIDERHDDPESGRLPRRQTGRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9B8</accession>
    <name>A0ABR1X9B8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002386</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673997.1">
        <property type="nucleotide sequence ID" value="XM_066806701.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039761"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="6">
        <location>
            <begin position="7"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8092025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="22631" checksum="305688F4FB64CC5A" modified="2025-10-08" version="1">MDISTVNLRTQKRLAASVIGCGKNKVWLDPNEVSEISNANSRQTIRKLVSDGLIIRKPVTMHSRSRARELNAARRIGRHRGFGKRKGTADARMPEQVLWMRRLRVLRRLLVKYRASGKIDKHLYHELYHSSKGNAFKHKRALVEHIHRAKAEKARERALRDEMDAKRAKTKAARERKQERVAAKRNALMGEGEESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9N0</accession>
    <name>A0ABR1X9N0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sulfatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000055</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674143.1">
        <property type="nucleotide sequence ID" value="XM_066804370.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037430"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16031">
        <property type="entry name" value="G6S_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108:SF6">
        <property type="entry name" value="N-SULPHOGLUCOSAMINE SULPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="508" mass="58457" checksum="FB902A5315668B84" modified="2025-10-08" version="1">MADDHAAKSISCYGAGINSTPNLDRLAAEGMRFNHCYVTNSICTPSRAAILCGTHNHVNGVVTLDSKINKRLPNVAKPAALGHAAPAPRRTGGKGGYQTAMIGKWHLGEGRDHEPTGFDYWSVVPGQGEYWDPQFLEPGGKTTRVPGYATDIITDKTIDFIRQRDKSRPFFAMCHHKAPHRSWEYDSKHKDLYKDPVRLPDTFTDDYKNRANAAKVAKMRVAEDLTYTDLGLVQPEGPAAEVGVKMIDRWNWVDRKAFTFKTPAELAEFKFQRYMQRYLRTIQSIDDNVGRLLDYLDQEGLAEDTVVIYTSDQGFFLGEHGWFDKRFMYEESFQMPFLVRYPREIRAGSVCDDIISNVDFAPTFLDLAGVRVPTYMQGYSFRSLLNGKTPDDWQQVAYHRYWMHNDVIHNAYAHYGVRDQRYKLIYWYCEDLGLEGARPSPGGEEGRDKEWELFDCEKDPLELFNCYHDPEYAEIVSMMTRKLEEKMAEIGDEPVHDQRQLELCRKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA53</accession>
    <name>A0ABR1XA53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674310.1">
        <property type="nucleotide sequence ID" value="XM_066804537.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037597"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8093537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="23602" checksum="1D1561B8B7B50C34" modified="2025-10-08" version="1">MPEPPYLQVPGDDIDNIDHPQHTTRKTPWLPLKAACVVFASFTVGCLVTYPIAAYTALSGAQHAPGNNLKVPSFPQFAPESDANHNRGFPTQAGLDGAPSEENQRVWDALVPIGRGFVNVSSPETYGLLRGIPSESGVDRYSMAMYHQLHCLGVLRAQFWKLVDMSEPGWTDAARLEAVRHIVRSRHAQHCIAYLVQGVQCSADLTVEWADIGGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA89</accession>
    <name>A0ABR1XA89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674286.1">
        <property type="nucleotide sequence ID" value="XM_066804513.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037573"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043:SF8">
        <property type="entry name" value="DUF4220 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="488" mass="54820" checksum="E63BD87E079B1ECB" modified="2025-10-08" version="1">MVAITSKCPSKLSMLFASWKSPDPVEKDEEAQNVNDKIEEAPSWTLTHCFLANMGGFRYQHGRKRFPLTALQIAENKSGLFNNPEMTENDIQERSKQDWFVKVIATLQFLQLALSLIVRTSQGIAFSQLETITVGFAVCGAIVYLLYFYKPQGVQACFVSCLPQASPGLSSSAQLLQYTKTYDSFWDVLRNKRRSDEDDSSNSTTIVDRIPNDNIPISQNQWAHPGIFLLALTSALFGAMHAIAWNFEFPSVPEKVLWHVATIVSAASPVAGLLLIPVAQLTMSSGDPHVFLGNCLRLVREASWHVYDKAPWHVYDEVSWHLHDKDAVQTVYKRLESIYLKPDPDCEDAQVPYKEIFSGSPAASRLPRQMVDLFNMKGESEKAGGDDLGKAVLASYPKEFASDFCMLIRLMEERESKKLNDTAKTNVFPRRIWLPEWLNHFVLYATSVLYVLARLCILAVGLSSLRQMPASVYKNTPWTAYIPSVGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAI9</accession>
    <name>A0ABR1XAI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674499.1">
        <property type="nucleotide sequence ID" value="XM_066804726.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037786"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07040">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17533" checksum="7CB43B41590C8C0D" modified="2025-10-08" version="1">MRRAQIELSVKEVSSDGQPDPILDETGREQCEELSSNLRNAIITAGVPAPEIIATSPLTRALETTQMGIMPVFPPDRKEPYQAIWSRVQNTISLLFEENPQSLVILLMTHCYVQQTIQREITGWDVPEEERKESVEFFVGDARGFTKPEFPAFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB36</accession>
    <name>A0ABR1XB36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH-ubiquinone reductase complex 1 MLRQ subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000549</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674637.1">
        <property type="nucleotide sequence ID" value="XM_066804864.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037924"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="9179" checksum="37710CB1B93AB4BD" modified="2025-10-08" version="1">MYPTRALRMMPTRRMMRHTVSQRLRKLKSIPAELIPLGVVVGFAVFAAGYSSFRKFTVDKNLRLARQNRAAEAEHEEHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB97</accession>
    <name>A0ABR1XB97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000584</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674672.1">
        <property type="nucleotide sequence ID" value="XM_066804899.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037959"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF43">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="44198" checksum="25EAAA174D3ACBE4" modified="2025-10-08" version="1">MAPPHAQPTSGPQEKSDNVNLTYVSQRNDNRVPVSLVGAALESDGVGATSNHSALVISSHLHGIRLFLVTILNAVMLFLVQAEIFIVTTSIVAITGELGDFDAASWILASYFLGYGVGGGGSYALATIVTIEVVPPEGYPTQMTYMGIAVMLALILGPIAGGGISSVATWRWIFLLNVPIGVVGLVLAIVGIPAGFPHHQRKKPGNEARGEISQQRARPLNRLDMPGGVLLLLATMSIVAAFQEAGSRFSWGSAYFITLLVVSILLWLVLVIWERRVTLANAVREPVLPWRFLRSRFMVGTLLFQTLILNIPHVAEKRDHGESLPRRINLLKYLELTEVYWQSRGDGSGKSVSRHRQHAHGGSDHGALQRVRVSAVVGAWNLGPESRHRNIQPWRDSRDSRGRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBA8</accession>
    <name>A0ABR1XBA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674714.1">
        <property type="nucleotide sequence ID" value="XM_066804941.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038001"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="718" mass="80197" checksum="4BEDCD7906E11845" modified="2025-10-08" version="1">MRHPLEQCLPDQAEREKLDAALERMARTEGSMEIVVDGETPSRKSTAITTHAYRKAQSIKERRKRVVFVGEDHVTTACVKQWLDSTYAEGGRLYKKIETHNVSQGLEKEGALVVSTMRLLSSLLFNYLVRPDDYSDGARELLTDAILILDHNGVPGGFWSTAWLLAKVTIRDFGHVSVIHLTHSRLKRDRIRWIGITGAEEGQRVDVHLQAVSTVLRHRYLDGPSRWLEPAAQASQAVALVEQHKEEGVACYLPDTVAHMVLRQLHEAKATYVAEGLYKQEFLCGHAPKVVIFRDSDGSLPIRNVNHLVVSGLTEAKRFDRVLGKEVRALTWLRQDRVDQQLDTLRHSLAYRREVDESATVTVHFLFSEEEHDRIRHADDDGDDSGHLDLRLALLWYVVRSVSPNIEIARILPDTYRMEVLRRFRQHGLVEDRVVFQGLACLHLLMDHEGLSDRAPPLEVLMMIALNLDENLGAVASEAQRLILAFLTCFVRWDSPDIMADRMLDSGLEPGWQHNDARAGEVRTAVRAVLEGGDDVSPLWRGINKRWATGGLWLLCSLARRFESEKTAWKTLVPGDRGVAVRDPTAMWMRTGERVDRCRDGASEGLVTSAVGDSGGLGLCSLVQRGAGRVVAEVGASRRHDAVDGVQAAGHSREGGLPPERMYAVAMEYHERGGVYMASGLVQISARVVAEFQKKIGMYLFVGLGSSLRLDPMPPTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBR0</accession>
    <name>A0ABR1XBR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative lipoate-protein ligase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LplA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674853.1">
        <property type="nucleotide sequence ID" value="XM_066805080.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038140"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16443">
        <property type="entry name" value="LplA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004562">
        <property type="entry name" value="LipoylTrfase_LipoateP_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561">
        <property type="entry name" value="LIPOATE-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561:SF3">
        <property type="entry name" value="LIPOYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="5">
        <location>
            <begin position="71"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="401" mass="44368" checksum="6DBFDFE84FE55E84" modified="2025-10-08" version="1">MASATRTLARSRIHSLAWRPRAPPLAPRHHRRLFSAEAVAHPTNRVQIYLSRSHDPYLNLSFEHYLLQKSHPDSVVLLLYTNRPCVVIGRNQNPWLEVGLGALNQPALLAPPVGQGGVLNGDDADAEPLGVQLVRRRSGGGTVFHDLGNVNYSVLCPPAAFDRDRHALMVVRALQSLGVSTARVNERHDIVLADEQDASTTFKVSGSAYKLTRLRSLHHGTCLLSTPNLDRVGRFLRSPAAPYMKARGVDSVRSRIRNVGVANAAFEEAVVAEFGAMYGNVDVETIATRDIKEIPDVMRGYEELNSLDWIYTQTPQFTFSTRPTEDDPRPRPPLPNYLPKDFDLSITARHGQITEATGVGIETSALGSVYLHKVSDWRPLIGKSAGSWLNEMFGARPHDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBX0</accession>
    <name>A0ABR1XBX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000891</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674979.1">
        <property type="nucleotide sequence ID" value="XM_066805206.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038266"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF21">
        <property type="entry name" value="KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="112"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="432"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="780"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="857"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="934"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1330"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="266"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="501"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="539"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="573"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="668"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="786"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="860"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="939"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1009"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1332"/>
            <end position="1347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1401" mass="153552" checksum="EC499EBD8B588D31" modified="2025-10-08" version="1">MSSPPFHPENAACAAPMSQSSPDLHPAQLEQQPQQQQQMLIAPSPAPPLPAPPPSAQPSPPSPHPHPITSSTTTSASTPGVGLITATGISNVVADVDSASPNLEPESVAVTAIIGTTNDTHTTSTSPVPVSHSHVPLPAHPAGNVSPAGPGTSTSLPNSTSSISTLSSSSSEPSTPVADPSNNKKSRPPTVSLRSNGPSLLTQALASARGIPPNLSSLPSHTQQQDTRRPEQSPTRTNDVANNSQPRNTPDAPTPRPTTDSRDALPNQSRGASLTPPTNSDHASTSPESSGAQTTSPESHNASAAPLRTPAMPALADTRFDTAHESISDPKGRPRSLERTYKEIRTYPSGVNGTTNGEDAPFSRLFGDENSTIVTSNGHTASEDTRAQYRTWRQERTLSMGPEKAWSIGNGDLVDTEAGQVEKSIAEALAGVEPTRSRKASHSLRFFKEGLPDGQAKRKDNRNTPYHHEANSSLSSAHDVANLIDQELRSPRFPGRTNSFPSASSVVESPSEAGESDYFSIKRTSDVFDEEEQNYAPAEHQESPEAEHDTPDTDATLKDGKTQPRRGLPSAAENDETPEEGEFSGEEKISSAVFVPHQGLEGMNKTQPRRETAGRPAPVHRGSNPEGPGPWLVKANEPEDDGGPDPHESGQTPCENGDNGFARGADGPADHENAIKDDHEDGERACAPSRTSRAIHEDQVHVHDHQIEPAAPLEAIELIPYKHQVGGHTTLWRFSKRAVCKQLNNSENKFYENIERFHRDLLPFLPRYIGVLNVTFQKQPRRKSIVKRDENPATDEKDIDHAVQPADDRLYPELLKSSLAGTVAAKEHRRVISQSMQSGPTPIPTVTFVDNQHILPRSFLQPSGTSPPQRARSQSDAAACFDSIEKSSEPNRGVNGELVRRPTLEDRHAKSWGATTVNKRLRNEVFNDAFLKQPIAVQRHQRPASHQRSIPRRHAHPGSIRSSASDPALERCRTESNNSVELVHGHSPLRPMPQLSQTQSDLGLQGGHPEADHTEQVKDVTGTSAPEAETMTNQFPHQRRKRRYSGTGLRRRPDDVSGSRGALKYFEDVDDAGYKGDAAANGSHVLSPAEPEREQAMSTMERSNYSSAGASELPSPTLEVKKIPRPVNPKEAQTRQESIKFFLLLEDLTAGMKRPCIMDLKMGTRQYGVEATSKKRESQRRKCAGTTSRELGVRVCGLQTWDVKEQRYLFKDKYYGRNIKAGDEFQQALTLFLSNGIDDSSVLRHIPKILQKLNQLEETVRRLRGYRFYAASLLMFYDEDTNEDDYDTMVDDSTTDFATDTEETVDARRRRRRDKKEIDFKIADFANSVTPDDLRQDKPCPPRHPDEPDGGFLRGLASLRKYFLKIQSDVRAELGLASHYRQGRTCDFDQMDEVADDLVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC56</accession>
    <name>A0ABR1XC56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674989.1">
        <property type="nucleotide sequence ID" value="XM_066805216.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038276"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF56">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0045">Antibiotic biosynthesis</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="3">
        <location>
            <begin position="125"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="434" mass="48769" checksum="707ED1B477BB316F" modified="2025-10-08" version="1">MAPIALEADSPVVDHIEQLKSTIRHPNRSVFPDGLKTSGTSRNACLPLGRISSPLTNKPSTGQHPPLYDQIYPYSSFPKSITGPTVWNPEDYSDNPERWVHQFSADEINEISQAADNFMSSKASLTGITKENFPLPNLAPSLHAMRREMLDGKGFILYKGFPVQQWGNHKSAVAYMGLGAYIGYPVSQNGRGHILGHVKDLGDDSTQIDKVRIYRTNARQFFHADDCDVVGLLCIAKSEFGGESDVSSIHHVWNILQAERPDVAELLTQPIWYFDRKGEVSQGEDPYIRTSVFYLETPDPANPDREQRVYCKWDPYFVKSLSRFSDRGIIPPLSPAQAEAAQLLEDTCNRVRLHMILDVGDIQFVSNSHTLHARTAYRDFGPDSGKPRRHLMRLWLSVPEGEGGWRLPFWDSNEKKRGGIQVDDTPPVARLDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC84</accession>
    <name>A0ABR1XC84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Signal recognition particle subunit SRP19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000941</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675029.1">
        <property type="nucleotide sequence ID" value="XM_066805256.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038316"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.30">
        <property type="entry name" value="Signal recognition particle, SRP19-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002778">
        <property type="entry name" value="Signal_recog_particle_SRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036521">
        <property type="entry name" value="SRP19-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01922">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69695">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="274" mass="28821" checksum="9251551C7AF78A68" modified="2025-10-08" version="1">MSHARIEEVSDSDEASDPSEGDIDDFADSDIMRQILYNPAPSPVSFPGTQQQSITPQDIAHYQCIYPIYFDASRTRAEGRRVPSALAMANPLAREIANACAALRLQPVFEAHKLHPQDWANPGRVRVPPLNDADKNTNKSIKNKHHLYILIAKWMKDRGPTTGDSEALRRVRIPGLPGMPEDGKPWPKPPAAMTGGGVSENALRDMMKEMGGMGGMPGMPGMPGMPGAGGAGGGMGGMGDMMSMLQGLGGGAGPSEPPAGGAGGKKAKKGKGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD89</accession>
    <name>A0ABR1XD89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675402.1">
        <property type="nucleotide sequence ID" value="XM_066805629.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038689"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="9"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="320" mass="35922" checksum="A407396FEBE36D20" modified="2025-10-08" version="1">MTINEDVPGIHAAVQINGVEVAEYEAPDAGDEDAPVPTVTKYVECIDNANFTIRMGVNRAYEWGYRNHALSLQVYVDGHWVIGKLFKSPMAPDAGFFPPAETVIRGREEINPSTNEWVLRNFKFASVTTVDEAQQERVKDDLKIASKLGVIEVQVLRGIVGGEVVSRPGNIKNNKFELSEKSLKGKAVSHGTNFESGTRLDRVPRYSDFEPLPEDRGPIAIFRLIYRSREALKREMIIPRTPPPRSPRLAALTDAERDRLARERLEQLKGTKVKREGDAPVKREHGDHYDLIQDSAPGRPSKRTRLNSGEEVELIDLTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDK4</accession>
    <name>A0ABR1XDK4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675522.1">
        <property type="nucleotide sequence ID" value="XM_066805749.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038809"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="655" mass="73177" checksum="4838A3F56A4C6DEA" modified="2025-10-08" version="1">MADRVGAAEGDLFQPLDYIPKLSGYLSREGYDEDNASRMQECSCQILRTYPSELPVQRWSAAKPQQVFLILREHLGDENLDLAGGVLYELIEIDCEYTDDPGAAFQRWRHDHMSRYQTDLELPHVPHMTTITPCIIPTEKLAHWRSQHPERYPFVLSDSGPPSAERFSGDRSCIRSRRAWLIDNTFYVSSKTGGTLPLNNPNPKEFHELQWKAQDTTGRLIKEREIPLNSNKRSEDIASRRASEARSTSTAQKDDTPAPRSSLLNRLAVRFSRKRKDHVQEEHRRSWLPSALVGEGSLSFKDWRAAHNTAPVPLPDGCGVPHAIFARKNLLVDEEENLPSFAAVSQMPVAETKATDAAIEAAAQSSHIGHEQLWRFRGPFTPQLGHSLDSQRPTTREARCKELEQGKGHKPRVASDSTTPHGVFPTMGVNRRVSHFGLDGVLEWLASSEHISEKPTPASTCSRLENIEAGPPAPHPVPPPPLSERPLNERLRLAVQVRVQPRSVIQTDSEDMRLIVKLSSDKSPSSLPLFENIAFVMSGNRSENHGPSSNRKATIIQLSPTLSSQYTSTSELHRSRRMCPVHKRSYLSFSSSTTRGESECGSDDNVGCYECAKEAEGELLAPRPPIVCELLHPRPRLCGVSQGVTAERLLDLEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDL9</accession>
    <name>A0ABR1XDL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Low-affinity Fe(II) transporter of the plasma membrane</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675490.1">
        <property type="nucleotide sequence ID" value="XM_066805717.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038777"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007251">
        <property type="entry name" value="Iron_permease_Fet4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04120">
        <property type="entry name" value="Iron_permease"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="495" mass="54757" checksum="9B6C1FD2B287ACB2" modified="2025-10-08" version="1">MGYHILLHQEGDDSGVDRGRKPASGGAPKKKTNVLDAIVRAAGSRWALGITFLLLIAWGVWGIVGGPTDTWQVILQDVSSIQAYFSATLLLRQQQGSCKDILGRICSLISRGQSNERMLSSLPSADRERLRTKKQVRMRNEIFDSMQTKEDILDRVANAVSAAVGSLYFLAIYWAGIITWVVWGVPLQFSNTWQLYVNTATALQITVTTMFLQNIRKQHDKHLEKCIENIDTLDTEIEMELRLLTGDTTPNPVVASTPPTLNRMQKGIDIYAFIVGGSIGLTISAAVFTLWAAIGHQLEFDDNWWLIIGTYTGLIGFIDSFIMKNVDYRETELAKQHFQRLMEQDYQLFKLLDAEMPPAEGADENVKLSLGLRLSNAVGDFCASTGASYAAVGTVVALLIVASAMQWTETGQLLCNTPTMIVEGFLLIMLLQAHNFADGRRRVVHDDILRRRIAMQGYLTSSGETPSVTAPEPVYVVSTDEEKRASAQAASGYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE04</accession>
    <name>A0ABR1XE04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001598</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675686.1">
        <property type="nucleotide sequence ID" value="XM_066805913.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038973"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF78">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01370)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="98" mass="11163" checksum="FA66253B14B469AF" modified="2025-10-08" version="1">MDQPLISSDRANIGNVKILQSGTDDNISRALHLVGRDFNWLNGRKGLSSWQWLFITESAITIFMAVPVYFLLLTFPETSTALSERRMFITRQGDGNWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEB4</accession>
    <name>A0ABR1XEB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7702 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675818.1">
        <property type="nucleotide sequence ID" value="XM_066806045.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039105"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056119">
        <property type="entry name" value="DUF7702"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109">
        <property type="entry name" value="UNPLACED GENOMIC SCAFFOLD UM_SCAF_CONTIG_1.265, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24800">
        <property type="entry name" value="DUF7702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7702" evidence="2">
        <location>
            <begin position="6"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8095045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="148" mass="16201" checksum="20A7B90C44CFF632" modified="2025-10-08" version="1">MDNAHKASAIAQIVFYAPIVPITLYVGVRAWKYGPRLAWYPAMAFACVRLVGGALALASLIDPKNMSLIMATIVLLNIGLVPLIMPFHALTRIVLEESFLESKRKKWFITVTRWLLLVAVALLSTAGGLTGNPEMAPTQSILSKVAYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1USY9</accession>
    <name>A0ABR1USY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_015382</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660581.1">
        <property type="nucleotide sequence ID" value="XM_066819696.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052756"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056693">
        <property type="entry name" value="DUF7791"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25053">
        <property type="entry name" value="DUF7791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="320"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7791" evidence="4">
        <location>
            <begin position="577"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8061161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1023" mass="116334" checksum="8095C6597FCFD908" modified="2025-10-08" version="1">MDSKTALVALTMNSRTAIAASKMGFKTTIAASVPNSRRAIAARAGILIHAESWRRSGVVASISRPIKAVHWSLQALVDSSGKLTRGGLVPRIGSRTEGRDIACRVGFHRNRGGLLDLAYKIGSAGWSLYNSRNETPDELRQIGHVVADIREKNLALQQIRVDEKRNLREDELAATRLANECVKIATELEKVLDKLKIRDGHSKTLEVTRVVIYQRLRRNEVAENQSATMAEIEVLSRSKDELAINLSSRFEDIQDDILRLSEKSADLDTQAAQLRSLVTKLESFQRERSNWQKKIGVIESLHFEDIKRRWSNIEEADKFTNSWLFDESQTSFLAWLKGGSGMFWIGGKAGSGKSTLMKFASKHDDTRQALRQWAGSSQLNTANFFFWNQGYEMQKSKTGLIQSLLYQVLSKAPDLIPQICYDHPAHEQWDFNDLTAAFQSITERHDMPAKFCFFIDGLDEYGGSDEDLSQTIPGGKFQQKKYSLAIEHFTKGDMETHVRHTLGQNEKFQLLGNSDALLKEMIAAISKHAQGVWLWVFLVTRDLVKAVNHDESSKKLQEIIETFPKDLESYFENVINRIEPHYRQEMAKIFLITLEEVQPLPLYAFSLLERERRNPHYAIKAPMAAITESELSSIETPWKSRIINRCGDLLTVTPGPHPTFLHNSVDFLHRTVRDFLQDCYLPKLKSELGALEYSPLLSLCNMTLFLLKKLDRNDLSDRKLREKSIRRTIGLVDELLYYAHEYEAVEGGSDLVPILDEVDRVNCVHAGKLRNHWTHARDLPSRRGLDEYDEGDNYNFLALTVQARLVGYVREKLQTDRKRMKKDGRPLLDYALRPRRVTALKMPYHSARADPSVDVRMIRLLLEFGASPNQDVHLNRRTVWALFLLSMYETKNRDEDNYDLTTAWYAACELLVLHGASLDCWLEVQVIHRNRDMIASDIITKAMAAILKTGTSPWWRSRTKNTTKAARTTEEKARTRPLSGLVAFDDSGSRNVVPDSVSYPRRLVSSSLTSALVGLPAMDASLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUR6</accession>
    <name>A0ABR1UUR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribokinase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014768</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661270.1">
        <property type="nucleotide sequence ID" value="XM_066819082.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052142"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="113" mass="12670" checksum="C0D1972AB5CD30EF" modified="2025-10-08" version="1">MVLVLPGIMTVPNARSSVCYVLLDHPARCPLDERFSQYLTHSMVNESEAAVPHLMSMSSMQPVQGMCVRMCLDRIDGSKDPRGMDTIKIAHASDYMRQKARATWDIRSSVPCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVA2</accession>
    <name>A0ABR1UVA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014961</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661463.1">
        <property type="nucleotide sequence ID" value="XM_066819275.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052335"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF93">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="44"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="317" mass="34972" checksum="D095A10108FBDCEE" modified="2025-10-08" version="1">MIDGRGGETLVLVWTLSGVSLLMVLLRMYTRVAIVRSIGADDYAYATAGHIHTLSPDDAASAVFWEIMCQAAAVISMALAKISLALFLLRIVVVAWHKIAIWTSIISLSIISTSASVVLWTQCRPVNKIWDRERVGGYLRYSFDPSCNNAWILVCGGRFLPGHLPLVVHLEIEHAKATVELGGLDGPDFTYKTAPLVIWSAVEIAVTMVCIVIPVIRPLYRTISESARSSSSYQKHGAGRDLSQRDSSVQLRTIEGSSVDGAEYLSPNDLLKRDMRLGLRTLSITHIVSNKPSQEEMLRDEYQNSVKVTDEVSVSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVZ7</accession>
    <name>A0ABR1UVZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661687.1">
        <property type="nucleotide sequence ID" value="XM_066819499.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052559"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035:SF3">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8063088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="201" mass="22529" checksum="5ACD9ABB844D23EC" modified="2025-10-08" version="1">MAATEEYFDLLPLDLDPQTKAVQAPANASKALHAELAALNSLHRSILTLENTPQIPRRRSPQRQRPVPQGQARRGRQDVPARYRDGPEAPLWEPQGLVREEVAQLFANRAQAHMALQNWAEGAVDAEASVEAKRAGNAKAWWRRGKCLLEMGRLDEARDWVGHGLEMEGEEAELLALQQEVLARLDKKNRHEEAKALSEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UX23</accession>
    <name>A0ABR1UX23_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661185.1">
        <property type="nucleotide sequence ID" value="XM_066818997.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052057"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="59" mass="6647" checksum="2F661DD01A7E37E2" modified="2025-10-08" version="1">MSAATEFWSFAKRNRGVVKLPSQERFEQDPIPCTNISCEKLVATLRRLFGVNGYEVSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2K8</accession>
    <name>A0ABR1V2K8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012175</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662181.1">
        <property type="nucleotide sequence ID" value="XM_066816489.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049549"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF6">
        <property type="entry name" value="ACYL-COA SYNTHETASE FAMILY PROTEIN (CEFD1), PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="89"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="234"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="486"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="619" mass="69523" checksum="28A49CC9A306A92B" modified="2025-10-08" version="1">MALAAGSAMLAAAAYLDGKYQLRRDWKLVRNQKEGERLHAQRGGQDVPVVYPGRDLQKVAQRKSHLVPGPDSDVPGTVRDVRKIRPVALEQGIRPGDLVAVYLLNSVEFFAVMFACHCIGASPALINYNLEGRPLHHCLDVCESKVLVVDEDEKCQARGGRKQGLHRVEEDGHLHFGQRIQTANRGETAGGSGRELAERHGGNFPVLPYLHQRYHGAAQGLCIQSESTYYNLPFGCKPGVDCWYNSMPLYHGTGIISTTTLLLGGVGLAIAPKFSVSGFWPDVTESGATFFIYVGETIRYLLNAPPPPEQLRKHRLRGAYGNGLRPDVWTKFQERFGVPEIAEFFSSSEGMLHLLVWDRGPYLRDCVGHHGLIQRYRMRNTYVPVRIDHETGDEIWRDPKTGFAQRVPYEEGGEILVAVPDQKPWQVYWKNEEASNKRFARDVFKKGDLWYRSGDSLRRGKDGHWYFLDRLGDTFRWKSENVSTAEVAEVLGRFSGIAEANVYGVSVPHHEGRAGCAAIHLDPAVSADTLDYEKLAAFAKSELPKYAVPVFLRMVSASSHIHNHKQNKVLLRKEGVDPDLIGTEEKGNKDDTILWLQGDRYVPFERTDWKSLQASRARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4E2</accession>
    <name>A0ABR1V4E2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TRP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661889.1">
        <property type="nucleotide sequence ID" value="XM_066816197.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049257"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF1">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="53999" checksum="17A6FB08B8B04CCE" modified="2025-10-08" version="1">MTWGDPTTDLVNTARELMFRSAIAYSNFNRTAAGVQRIRVSQTRAANAYKSRFDYFGITVGCMVLQALVISYMLFGWHRLGRDVSLDAFEIARAMGAPALQDASSNSRIDVALSRLRRDKFRYGELVSETSVDSWTGADQSQGIGQGTSSHDYVFVTVESDLDPTAVGIYEGHTVPSYFSLFIFAFVYELVLVYDALRLNSMIQLVGLCIFNTLLLLYAAAQPSGVKKALDVLAHAKNMDITPLLKPGRHTWERISPALTAVIVDQAVATAALFVLTYKLRSEFAWVVYKVLNADLSMKRRLLNFQVYMALIKFNFFFLVGFLVQTVSLVPDRNHDPEFPLTIVGIFVAFAAMCLAIYCATYEKKAGTVTIIVRPELTNAFPSVSALTEEYRQVAYMGAAAYLSYKLSVLYSEDDYPLITFNCVALAMVICNIVMAMVCMANFGKGLSTYTRPQKKLPQEDFHLHDTQSFMYSGVRASRLDLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4J3</accession>
    <name>A0ABR1V4J3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acireductone dioxygenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Acireductone dioxygenase (Fe(2+)-requiring)</fullName>
            <shortName evidence="11">ARD'</shortName>
            <shortName evidence="11">Fe-ARD</shortName>
            <ecNumber evidence="11">1.13.11.54</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Acireductone dioxygenase (Ni(2+)-requiring)</fullName>
            <shortName evidence="11">ARD</shortName>
            <shortName evidence="11">Ni-ARD</shortName>
            <ecNumber evidence="11">1.13.11.53</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ADI1</name>
        <name evidence="13" type="ORF">PG997_012861</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:49016"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.53"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16723"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="11">Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the acireductone dioxygenase (ARD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.54" evidence="11"/>
    <dbReference type="EC" id="1.13.11.53" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662867.1">
        <property type="nucleotide sequence ID" value="XM_066817175.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050235"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02232">
        <property type="entry name" value="cupin_ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03154">
        <property type="entry name" value="Salvage_MtnD_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004313">
        <property type="entry name" value="ARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027496">
        <property type="entry name" value="ARD_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418:SF0">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03079">
        <property type="entry name" value="ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 11" id="KW-0408">Iron</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="3 11" id="KW-0533">Nickel</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8066114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="171" mass="20258" checksum="B768A5659EF836E8" modified="2025-10-08" version="1">MKAYWYDNVEGDQRLPHDSGRALSEAELAAVGVTYSRHPTLATVDQLAEERGYRNRDEITVSPEKMGDVYEDKVKSFFSEHLHEDEEIRYIRDGAGYFDVRSRGDEWMRIYLEKGDLIILPPGIYHRFTTSESNYIQAMRLFKDEPKWTPLNRSDELEENQHRKEYVRQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4U0</accession>
    <name>A0ABR1V4U0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662084.1">
        <property type="nucleotide sequence ID" value="XM_066816392.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049452"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="28198" checksum="859F9D163B82B7AA" modified="2025-10-08" version="1">MGAKSGIALKSLQWFIRGIQFCCAALILSLFSYFLAALSNHNLPIPTWARAVEGISGVGVLYTLAGLLLLCCLAGHPVTSFIAIVLDVAFIGAFIYVAVSNRGGASSCRNSPNTIFGTAVSIVAIVFFILSALVEVVLVRHRRKEARFGPSPANNYTSGYGKRGKFMGLFKRRGTGATHEDPNALPMHTTPNQVRQSYNTESTAVGHEPAGYPKYGEAGYGGQHEGHTAYPESGVTGNNAHLSPHNNPPFAPQHNSNFSTGYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V684</accession>
    <name>A0ABR1V684_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663455.1">
        <property type="nucleotide sequence ID" value="XM_066817763.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050823"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="277" mass="32521" checksum="01D611D9802E72AE" modified="2025-10-08" version="1">MYYNNTRPRLMVLRDLLQDSSDEAYKLASSIARNWLPDNYAIARDLRDSSLPMHTTTNKFYPFKIQARRLIYHLRLEYRKILVELKDRQGSRKVQGDLDLRRRWMETSAHHSNILVSLVAEADGIINQLEFHGQTIWETAQRLGNSEKKHKEDIKKLQNQWSYRFNPWAATIHPYNYEDDANLIGTYLGRIHTAREGFKVRRELLRAAYESLASLESIDYQEEEEEASQQSSSGYPRFGHDDQRLADSMVRHLGAAFDCEEWASDNAEDPETCDDMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6D6</accession>
    <name>A0ABR1V6D6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012331</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662337.1">
        <property type="nucleotide sequence ID" value="XM_066816645.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049705"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051370">
        <property type="entry name" value="PPIase_Pin1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10657">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10657:SF4">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="WW" evidence="6">
        <location>
            <begin position="4"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="120" mass="13657" checksum="239356BFEE00EB73" modified="2025-10-08" version="1">MDESGLPSGWEVRHSNSKNLPYYFNAAEKISRWEPPAGTDTEKLKRYMALHHSTSASQPGAQKPADKIRAAHLLVKHRDSRRPASWRESEITRTKDEARSIIQGHEARIKRGEISSANWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6K0</accession>
    <name>A0ABR1V6K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663579.1">
        <property type="nucleotide sequence ID" value="XM_066817887.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050947"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="1">
        <location>
            <begin position="15"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="70" mass="7658" checksum="8D50BE4372B714B7" modified="2025-10-08" version="1">MNPPPYTGSPDRLSQNYRLGPLGFLNGKQMAELGLLNIGMLDQRLALHWIQENIAAFGGDPSKVTLFGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6L1</accession>
    <name>A0ABR1V6L1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FAD/NAD(P)-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013294</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663300.1">
        <property type="nucleotide sequence ID" value="XM_066817608.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050668"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF315">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE MDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="129"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="491" mass="55144" checksum="43275EBDB76DCD8C" modified="2025-10-08" version="1">MTSDHNVPKPVGSYPDSGIDVLIVGTGLAGLTAAIECFRKGHRVRVLERHTEISTMGDMYFMGLSGTKFFKHWPDMAKEYDEISLHNCWMETFKHDGTRMIPVLKVAERLKEAGLDPNTPPGAFQMRPLVYKMFVNQVTRLGIKIEFGKRVVRYFEDEARSKAGVETDNGERFEADVVIAADGVGSKSQEVVGGQVRAASSGRAMWRAVFPVEVLDKNPKVKEFFKLKDGKDPIVRTFLGPGSYGLTLTRHDVIVWIVNHDATGDERESWNHTVEAEDVLEKIDDSVHCAEGWAPIFKDLVRITPPRTIVNFELFWRNPQQSWSSPTARIVQIGDSAHSYMPSSGNGATQAIEDAVSLASCLQLGGGRDKVPEAVRAHINFRFLRTACAQKLGFANAERLQDTDWAKAKLDPRKAQPKHPRWVWDHDPEAYTYENYSKCVEGMRKGISMDENDDIPPNYPPGYKYVPWNIDDIMKDLDQGKSVDLGAGDWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V741</accession>
    <name>A0ABR1V741_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Guanine nucleotide-binding protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012812</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662818.1">
        <property type="nucleotide sequence ID" value="XM_066817126.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050186"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="39579" checksum="540B0ABC2DB77E9E" modified="2025-10-08" version="1">MGCGMSTEEKEGKARNEEIENQLKRDKMMQRNEIKMLLLGAGESGKSTILKQMKLIHEGGYSRDERESFKEIIFSNTVQSMRVILEAMESLELPLEDQRMEYHVQTIFMQPAQIEGDVLPPEVGNAIEALWKDRGVQECFKRSREYQLNDSARYYFDNIARIAAPDYMPNDQDVLRSRVKTTGITETTFIIGDLTYRMFDVGGQRSERKKWIHCFENVTTILFLVAISEYDQLLFEDETVNRMQEALTLFDSICNSRWFIKTSIILFLNKIDRFKEKLPGGDDYAAACDYILNRFVSLNQHETKQIYTHFTCATDTTQIRFVMAAVNDIIIQENLRLCGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7G2</accession>
    <name>A0ABR1V7G2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663014.1">
        <property type="nucleotide sequence ID" value="XM_066817322.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050382"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="139" mass="15714" checksum="C32BE670F0671E7D" modified="2025-10-08" version="1">MRTDFLDVNGKQFVVPMEGKHEHAWIDIGTAVSLGVSTRGVQESGLFRTFQLPLFPSFHSQHVQHVHQIKWELTFACAGKKFEIGGSTRFALWVRVKSASNRSWTSSARMGSRELTGLGRTAMLTIQYSHLECRKHQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7Y8</accession>
    <name>A0ABR1V7Y8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sterol regulatory element-binding protein cleavage-activating protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">PG997_013789</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="20">Escort protein required for cholesterol as well as lipid homeostasis. Regulates export of the SCAP-SREBP complex from the endoplasmic reticulum to the Golgi upon low cholesterol, thereby regulating the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. At high sterol concentrations, formation of a ternary complex with INSIG (INSIG1 or INSIG2) leads to mask the ER export signal in SCAP, promoting retention of the complex in the endoplasmic reticulum. Low sterol concentrations trigger release of INSIG, a conformational change in the SSD domain of SCAP, unmasking of the ER export signal, promoting recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi: in the Golgi, SREBPs are then processed, releasing the transcription factor fragment of SREBPs from the membrane, its import into the nucleus and up-regulation of LDLR, INSIG1 and the mevalonate pathway. Binds cholesterol via its SSD domain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat SCAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663795.1">
        <property type="nucleotide sequence ID" value="XM_066818103.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051163"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030225">
        <property type="entry name" value="SCAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46378">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46378:SF1">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="19" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="15 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="18" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="16" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="8 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 23" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 21" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="408"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="430"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="24">
        <location>
            <begin position="301"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="21">
        <location>
            <begin position="673"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1004"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1105"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="22">
        <location>
            <begin position="1017"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00045958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAK8067042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1140" mass="127250" checksum="F6D078483AA73D2D" modified="2025-10-08" version="1">MIPESWQPSSVNLSYAVADALFAPDPSFSIMTAPTHPLRSVFTRYGRYASRHVVTTLLISVAVASILVYPFPFLYTNDFTNGASNLPHHVWTDAQPLEAKGPIEPDVIMRYIWVHGNYFEALDRDLLLGALELQDELLGPTTDFNPLQASPLEAPDASTAMHLSKEQRDAFHIINGVTDESWFFHSPLQYWSCDPQKIDNDLDILGTVNAKKTQPTSVNVTLRHSIVFSGKRFEDRHLVAADALVITLIHRRSSPIGRIWQTKAQELAAKMSDRYDVYPRDGTSMPSQLYEFQFRPLSIQDIMALGIAYMLTLAYFVVSLSKLRAVKSKMGLIVTVIAQLAVSIMSSFTVCAILKIDLSRIPSFAYPVVIFSMSLENVFRLINAVILTPSEDSTSNRIGHAFGETMHVALASVAQNLLILWGLSRLVSPGVAAFCTFAAIAIVFDFFYLSTFFLSVLSVDVRRTELSDALTKASIRNNRSQAEIQARQSWTDAMLQGKIAMSTRVAGTVVMIGFVLIAQWHFFENGSIVTSLGRFVGIGRKHGFPEFPRSQLSIDVHQARSPTSWLRLQDHETAREVIHVIKPDAHSYLAEVFDPLVFVAKGADRKPNVHERPFLPAVYDFVRHQSAPFVISILIIAAAVRLLMNYLLWDELAESHNNSDSADEPPLIIDTLSGGHSLDVAMLAASADGIIVSVGLDRVIRVWDMKADGASYTLSGNDILDTTFPKAMCINDSHWLALLTTDNVLLWDLHEQCWGPSIPVKSCRYKPEAFFFTADDTHGLPRLLLVRRDGTMIEIRPDREEAGSYVISGESVIVSVDALVDKPKSTTKLISSSREGEVFCLTQDPCGWSANAVNIARPLEKEFMSIVTLPELGYLLVVRSQSVDLVDAADYVTLHCFRTDPIQPRSLKCFHSKRRQMQCGSVGLKFLTFAYLNAFTRDLVVQSYTPQHDGESICFRTPGQPVSKTCCQWPRTRETRRVVTDPGAWEALPTGMIVGARKRTVVKPVTNGYPPTQGHTTLRRRRNSHNHSRPTTPKNNNDDDWEVWMLSQIGRGETWETMPLVSDQSGSQHLFVSNLGPMTRIGRGSVALGLSNVIKVIRVGHERFETSDENSPLNDPLRTVTNRRRNRGTTLKNRPPNTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9H3</accession>
    <name>A0ABR1V9H3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EGF domain-specific O-linked N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="1">2.4.1.255</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Extracellular O-linked N-acetylglucosamine transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_013667</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:12251"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:90838"/>
            <dbReference type="EC" id="2.4.1.255"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48908"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:12252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:90840"/>
            <dbReference type="EC" id="2.4.1.255"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.255" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663673.1">
        <property type="nucleotide sequence ID" value="XM_066817981.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051041"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF148">
        <property type="entry name" value="EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="11">
        <location>
            <begin position="323"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8066920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="486" mass="54518" checksum="9E174F4BC1C1B04F" modified="2025-10-08" version="1">MSLNKVLRPGLRARNVVIFALLISTTLVLLSSRRVSTFVLLESLGSNTETLSSILSSTPPPSHSSSLPIPLPSGYQNAPGQEGYCEQRYTTRYLETLREGEVSYCSPGSPSQLTCFHTPSDFHDDGHIDSFCIAQGSAFNAATNRFELGCSLRPDAEVPLSKLHPYWYRTGPWYLFHSHFSIAGPESPAWHPDAEASAKRTFSILVKREGPGNIFHVFHEIMSMTYTMDVLQMSRDPQTGKPRFSQEDIANTQVVIMDSFEDGGFIELWRLMSDRPIKRLSELVAEDPEWLTNNGNTIILPLAGGSNPVWHQTPEDHNCINQLREVFSKRVLDFYQIPQDESMVPTQGEPAPRPLTLTFINRTATRQLNNADGLLDEIRSRFRLEDVHVQSVNFARLPLRDQIQVARATDILVGVHGAGLMHALFMAARRGAVVEIFPATLDFNALRAIALERGLAYYSTHDTTREYVRPWQEESLDVDEGCLGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAH2</accession>
    <name>A0ABR1VAH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014058</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664064.1">
        <property type="nucleotide sequence ID" value="XM_066818372.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051432"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="367"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="382"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="410"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="426"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8067311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="466" mass="52053" checksum="36E84A3C232ADC17" modified="2025-10-08" version="1">MPAVIDWSSLLWPSSSTSKTQSYKASQQASNPVGAASAPQGPEASNLVQQPLAYLTGSAPVNPWILAATLGALLLAFYWTFARSRKVFGRHALLGSEPQKLLTGPTEDARQSVEFDTSELQNEMTRRLDEIEAHNKKALAEQVEAMQKRFQQDLDDKVKAIEGHVQKSLGQRLEDIDDDVRRRLKQSVEVFEDGLRTKLNKESFDGIYREVSLRMEALEEGVRIMDSKQLDVEAATIVQRALGQRLNTVEETLGAVEGKTRTSGQRADAFDDSLRVIDSRTKAMSQRLEAVEDNMGSIDATTTLLSHDVNRGEKAIESVSRQVKTLPDNDRLKEFSDIMETKFSEIEAKLEELEGGTPELTWSRVDSQEIEPSGPVYTNPELFKDPDLYTHPEGIEHTPDHHSDNDRSQSSRASRSSGGSSDSFYMKRKTSSSSMSKRKRLEAAGFTDTTFASRQRLFHSRTTSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGZ3</accession>
    <name>A0ABR1VGZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RmlC-like cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664318.1">
        <property type="nucleotide sequence ID" value="XM_066815028.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048088"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02226">
        <property type="entry name" value="cupin_YdbB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052044">
        <property type="entry name" value="PKS_Associated_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36114">
        <property type="entry name" value="16.7 KDA PROTEIN IN WHIE LOCUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36114:SF1">
        <property type="entry name" value="16.7 KDA PROTEIN IN WHIE LOCUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="2">
        <location>
            <begin position="39"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="136" mass="15023" checksum="07028DF08944FCA5" modified="2025-10-08" version="1">MPSPTSIPGTFSSFTEHWSPRLVAAVNDQHVKIAKIDGAFIWHAHPDSDELFYLLAGELTLELELPSKNDDDGGKMVKVEEVAMQVGDMFVVPKGVRHRPVAREAHIMMVERQGTVNTGDMAGESDRTRVPTDVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHA6</accession>
    <name>A0ABR1VHA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664335.1">
        <property type="nucleotide sequence ID" value="XM_066815045.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048105"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="144" mass="15729" checksum="9532A3E306E63E5F" modified="2025-10-08" version="1">MSTSANTLSFTAYPPGIIDGIRTKFGPLVAVLFAQIADENPCLDEARKDLGHWLGEEGAGDDCSVSDYEHRASEGSSTPRWLPLSTLEISFFSGEEKCTATDTVCKMLVQSMSLRGGVDEVDEGREQPTFSLHDLRFLPQLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHW4</accession>
    <name>A0ABR1VHW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664634.1">
        <property type="nucleotide sequence ID" value="XM_066815344.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048404"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF1">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="1">
        <location>
            <begin position="149"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="31468" checksum="EFB685EABA8F5267" modified="2025-10-08" version="1">MAETTQEELPPPFINIPGLPNFRDLGGVPHPIPSQPGKTVKRGLIFRSSEPSKVTDGGVQQLQDLGIKKVYDLRSLDEIKKDAEGGQRQVKEWEGAERVFAPVWRDQDFSPTALALRFKQYSDESDRGFLEAYKNILLAASSNDDKPYEKILAHLSTSDKPSPILMHCTAGKDRTGVLCALILSLCGVDDASVVAEYHLTDTGLKSRHDELMDFLMSDPAMAGNRAGAWRMISANPRNMQVHLNWIRDNYGSVEKCVVDLGLITPEGIEQLRKNLVVDEAVHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIG2</accession>
    <name>A0ABR1VIG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011241</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664846.1">
        <property type="nucleotide sequence ID" value="XM_066815556.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048616"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052377">
        <property type="entry name" value="Mitochondrial_ECH-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43602">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43602:SF1">
        <property type="entry name" value="ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8071038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="308" mass="31754" checksum="082CFC27E9D78D33" modified="2025-10-08" version="1">MKLPKLPPKAAYLTLSNPTRRNALSHSVLRSLRDQLHSYTVSPTAWLVDAEKWRTERAGLPHVLVLRSDASSSFSGSSGAADVFSSGHDLRELSASGGDAARDTFQLCAEVMSFLRRFPGPVVSVVTGLATAAGAQLALSADLPIACAERASFQLPGISVLGLPCTSPVTAVSRRLGLGMGYRMFALGEPVRAADLPLSGSSNVEVVKGGQDAVEKRVAEVVEKLAAQMPAQPQALGKWAFWTQAGFGGGAGRGGRGAPRRRGRVHRGGGVGGAGHGAACAVRGCTGGHGGVSGEEDAGMADMSRVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ50</accession>
    <name>A0ABR1VJ50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665068.1">
        <property type="nucleotide sequence ID" value="XM_066815778.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048838"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="92" mass="10807" checksum="CBBF569C307F4305" modified="2025-10-08" version="1">MVFRILDTIRKHHLTVRYASRHLFWTVPALYGYYTLYTKARASYHEGYIASARLMTAEGTEHFRQYRPEQQKKSSSSCCKSNLAVKQDVKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKP4</accession>
    <name>A0ABR1VKP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thiolase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010646</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664251.1">
        <property type="nucleotide sequence ID" value="XM_066814961.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048021"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012328">
        <property type="entry name" value="Chalcone/stilbene_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001099">
        <property type="entry name" value="Chalcone/stilbene_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011141">
        <property type="entry name" value="Polyketide_synthase_type-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11877">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11877:SF46">
        <property type="entry name" value="TYPE III POLYKETIDE SYNTHASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02797">
        <property type="entry name" value="Chal_sti_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00195">
        <property type="entry name" value="Chal_sti_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000451">
        <property type="entry name" value="PKS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Chalcone/stilbene synthase N-terminal" evidence="4">
        <location>
            <begin position="45"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone/stilbene synthase C-terminal" evidence="5">
        <location>
            <begin position="250"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="350" mass="37624" checksum="254E1EF8F5723BD2" modified="2025-10-08" version="1">MADSWAGPFRRTGIDARPAIHHYETGFGCEAEPPNIQDLDSYFREHGVDLAVQACQKALAEWGGELSDITHTVAVTCTNQGNPGYDVLVNRELGLDDNAERVLLHGVGCAGGVAIMRVASHIVLSFAARGRPARVLCYACELCTLTVRRELAEAEACTDKARLSIAGAIFSDGAAAFVLCNDAGLLSGRSNNEVMGDARKPLFEVMEWGNATIPDTVQEMSFLTETSGYHAVIGRQAAVPHGVPCIPADFDWALHPGGRVIIAGAQEELGLSDDHLRATKEIYQARGNSSSASVLAVLDLLRRRGRGRDHVAVASFGPGLVCEMVLLRRCRYVDEIARDEGRGAQNLVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT47</accession>
    <name>A0ABR1VT47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009088</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665365.1">
        <property type="nucleotide sequence ID" value="XM_066813403.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046463"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF158">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="41"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="352"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8074425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="365" mass="40464" checksum="371FDD22B67052A5" modified="2025-10-08" version="1">MESLPPPGEVTDVLNPESISWAGRLSIHLTLPIMVVAFIMRSIVRFRARQIGIDAYLLILGVISAASFCGILFPIFVQDVWGRHQWNTPLISIKPWFFQYSVTAGCIYNISALFTKTSLLALYFQVFRPSRLARSFIWFGITVISIMYIAVTVAMLAYMLPRPGDGGWGSMANTQRMGIPSRIIDLTQGFFGAFSDIYVLVIPIVVVSGLQVPLKKKIGLTGIFLTGLISCGYSVAGVIFRYQALYFEVDDHRWLSIKFEALCVAEVNIGILCACIPVFFVLFKPAIRKAETVFVYLKGRLSPRANKENAATDVTALPPPEILKQVPSGTLSGLKSFFRKVGHTQDRESEKTATSAQISQCTDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTK2</accession>
    <name>A0ABR1VTK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-1-3-glucan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009165</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665442.1">
        <property type="nucleotide sequence ID" value="XM_066813480.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046540"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF62">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="155"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="510" mass="56621" checksum="0FC21EE9384997D6" modified="2025-10-08" version="1">MFSCGLLRRPPRRRGRPLGRDDGEPHPAAPGDPNTDKNPFGDERADSRSQNYRGSGAVPSGSGNHHHHSSHHNNHNPNPFVSPEASRPASSFGSASALGARGVEDARGQRYFHSRRVKKGEVEKPWLEKKDPKEKWVTILPIIGILVGLGVSGFLVWDGLRSVVHHKYCVVYEDDFNNGFRKDIWTPEVQVGGFGNGEFEQATDSPENVYVQDGVLYIKPTLQDATLIEENAVINLTRDGTCTSKTLTDCVAVTNTTNGNATIVPPTKSARLVTKNGPATIKYGRVEVTAKLPKGDWLWPAIWMMPVADTYGPWPASGEIDIMEARGNNYTYAQGGNNIASSALHWGPDPANDAWFRTNVKRPALHTTYSAGFNTFGLEWSQKYLFTYINSRLLQVLYTNFDQSLFQRGNFPNVDANGTRMADPWSQTGRLNTPFDQKFYLILNVAVGGTNGWFEDGKSGKPWLDASPNAKKDFWSAKDEWFPTWTDPAMQVSRVVMMQQCDGDEGVNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTN9</accession>
    <name>A0ABR1VTN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665565.1">
        <property type="nucleotide sequence ID" value="XM_066813603.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046663"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045469">
        <property type="entry name" value="Nis1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19271">
        <property type="entry name" value="Nis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045324875" evidence="1">
        <location>
            <begin position="21"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="115" mass="11826" checksum="F18617FC910DF6BA" modified="2025-10-08" version="1">MVSIKTLVGAGLAALPSASAYIYGFENYVDYSIIWGIARTGLGSCAPDACVGTQIGYKNFYPEEVPLGNFTVDVTIPKDTPAGESVLTAAIPYLVGAGGLTKVAAYNATIDITAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTS5</accession>
    <name>A0ABR1VTS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase II transcription elongation factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665593.1">
        <property type="nucleotide sequence ID" value="XM_066813631.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046691"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019194">
        <property type="entry name" value="Tscrpt_elong_fac_Eaf_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09816">
        <property type="entry name" value="EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription elongation factor Eaf N-terminal" evidence="2">
        <location>
            <begin position="16"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="354" mass="38834" checksum="4251555E29D100E6" modified="2025-10-08" version="1">MASQADLVDPTKAGKYPVILSDELLGKPSTETFTGVRYNHKPDTNPSLSKLKVAGPSKYDLSYNDNGMYKYQGSRSGDGGQYVLIFDPSREVFVLHKVDSLFTMNLTQTPNNNSAAKLRQEFPHLEKPAKVSSGNINIPIHEKPKDTKGPATAAASAKGAKDSNTAPAKGKQKKETPAAKPKAAPKAAAAPAPPPKKPTPQSDDEEDSDDDDGGLVLEFPGGEEPSRDFSPAFPPRRFSEFVANGEEDDEDADGEEEEEDDMSEEEHFKLPSPMNPQKTQQQQQQQQQQQSSQQIQEPSPPQFSQPAQEEVESEEDEEEEEEEQQEDGFEDIADEDLEAQLEAELAASEVSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVW0</accession>
    <name>A0ABR1VVW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666302.1">
        <property type="nucleotide sequence ID" value="XM_066814340.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047400"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="98" mass="10952" checksum="ED9794CB84CD3FAA" modified="2025-10-08" version="1">MHHQATQPVQIATQQFVSTNFTREGSSSLSPPSVTTLQAQANRCETQDSDLLANEELQTIQVALSGGRRHRRGNLSQTELETFHLFRRDVRSGSIPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX16</accession>
    <name>A0ABR1VX16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Endoplasmic oxidoreductin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_009534</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">May function both as a monomer and a homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665811.1">
        <property type="nucleotide sequence ID" value="XM_066813849.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046909"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613:SF0">
        <property type="entry name" value="ERO1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613">
        <property type="entry name" value="ERO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017205">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045240732" evidence="17">
        <location>
            <begin position="23"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="484"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8074871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="565" mass="63166" checksum="B64302C89FEE9D51" modified="2025-10-08" version="1">MRPAAKHFYLSLFTLWGAPVQCKPSSTIAQDDSCAISPKSIVSDACASYSTLDALNQKVKPAVDDLTRGTDFFSHYRLNLFNKACPFWSDEDAMCGNQACAVATLDNEEDIPKIWRASELGKLEGPLAKHPGRKLQKERPQKPLQGLLGENVGESCVVEYDDECDERDYCVPEDESATAKGDYVSLVQNPERFTGYTGDSAKMVWDAIYRENCFQKSSFPHSASLGMTSAPRGPAAHDFRAVLQDAGRQQMLEQQFNNNQMQASASAGLEYEDECLEKRVFYRVVSGMHTSISAHICWEYLNQTTGEWQPNLQCYYHRLHTHPERLSNLYFNYALLTRAIAKLGSHLQGYTYCTGDRDQDADTKAKVLAVTQGASSVPEIFDESLMFKNGEGPSLKEDFRNRFRNVSRIMDCVGCDKCRLWGKLQTAGYGTALKVLFEFDNESKEVPVLKRTELVALFNTYSRLSNSMAHVRYFRNLLEGSEKEKSAVPDRAKKPHAVGTGTGPVEPLEVPLETEDDEWAGSDESQKEESKRKRLPTNSKRSLNVSSRPSNMSSRVGPAFPGACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXY5</accession>
    <name>A0ABR1VXY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_010375</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666652.1">
        <property type="nucleotide sequence ID" value="XM_066814690.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047750"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04906">
        <property type="entry name" value="ACT_ThrD-I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04907">
        <property type="entry name" value="ACT_ThrD-I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="entry name" value="Biosynthetic Threonine Deaminase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006674">
        <property type="entry name" value="PRK09224.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF11">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="13">
        <location>
            <begin position="406"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="13">
        <location>
            <begin position="504"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="15"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8075712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="584" mass="63702" checksum="139D322C49D735C5" modified="2025-10-08" version="1">MASTAASTDGAVLTNGITDQEPQTNGTANHANGHTRQTPSMSGLSLTEYSVNPTSPPRATRSEPLVPEDYLLPNGHPDYVRLINTSRVYDVCERTPLTPAVTLSRRLECNVLLKREDMQPVFSFKLRGAYNKMAHLSPEQSWKGVVACSAGNHAQGVAYSARKLKIPATIVMPEGTPNIKHANVSRLGGTVVLHGPDFDTAKAECQRLERTHGLINIPPFDDPYVIAGQGTIASELLGQTNLNKTEAIFCCVGGGGLIAGIGVYIRRMYPHIKIIGVEQNDANAMALSLEKGERVVLKDVGFFADGAAVKTVGEETFRICQEVVDEIVQVNKDETCAAIKDVFEDTRSIVEPAGALAVAGLKKWVAQNPSSNVNRSLVAILSGANMNFDRLRFVGERATLGEGKEALLSVRIPERPGAFAELIDCIMPHNVTEFSYRYSHDDVANVLVGISLLAPVSERATELQRLTERIGAANMSVTDLSGNELAKSHIRYLVGGRSTVPDERVYMFTFPERPGALQKFLMTLRTDYNISLFQYRNSGGDVGEIVAAIQCAEVQELEKFLKQIGYPYKDCTDDPVFKTFLRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W0X0</accession>
    <name>A0ABR1W0X0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666769.1">
        <property type="nucleotide sequence ID" value="XM_066814807.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047867"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="104" mass="10749" checksum="9C3C7C5383FFD0C7" modified="2025-10-08" version="1">MSSNNNSGYSYNSSGTNSQVSRGDGAAQCACVGSGHLQLITTYQGNHYCSRDYGSSDAISNSYHYSNTNPNGSTYHQSSSGTSTYTTPGGDTYRSSGGSSGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7N1</accession>
    <name>A0ABR1W7N1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD-dependent oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666962.1">
        <property type="nucleotide sequence ID" value="XM_066811620.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044680"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF32">
        <property type="entry name" value="FAD-LINKED OXIDOREDUCTASE AFOF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046262553" evidence="6">
        <location>
            <begin position="20"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="58"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="501" mass="53832" checksum="A2D64A933C8D3A35" modified="2025-10-08" version="1">MLARWVSWGLVAFAPSALALTDPQTVYDALSAILLPSSELVLVPDNAYQKDFTPRYNLAEAPSYIVGVRPAVAEDVKKAVTYARDSNISILTTGRGHGYTTSLGRVKGAINLDLGKFNSIQVDAGAKTMTIGGAVNGYQVVAALQEAGMEIPTPQCPCIGFAGASLGGGIGPYSGLYGPISDSLLSVDMVTADGRLLTVSETKFPDLFYGIKGAGFNFGVAISLTYQVYPAINNGKAMNADMTFLGSQNESLWKAVEELAASQPKELAFGLSVRYSPDPPSEGIMIAANFIYAGPRTKGKALIKPFLDLKPQNVNISTVAWKEIPLVANGGAIANFGCNPGVYYIPYSLNLYRVDVPNLVDVVNYMSQAIGADPVLQGTSIVWQEYAQYGFQLRADDSSAFSYRDVKAFVQIDSLATDASQAPALSKFGCELRDLLQRGSGKDQLDVYVHFAHGDEGSASWYTKEQLPKLLKLKEAYDPAGMFSWYNPIIPAAPPRSKFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W852</accession>
    <name>A0ABR1W852_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007478</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667135.1">
        <property type="nucleotide sequence ID" value="XM_066811793.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044853"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="313" mass="35391" checksum="CEA1C6F0932DA523" modified="2025-10-08" version="1">MVRLGLYQLGLQYSKDQTTKIITVHVGDKLPPSKMGVSFYMLAANRIVKQHLTVASVFLSRMCYRVPFQLRKVATANPDAQDMSHKGYLEALFCFTTSSRLLHAHTAKATSAVYTFLDTTIPNRKKATPALAQALGHFIRHTYGLPMVLDHILDEIGEGEKPPHQIAFVVLLRIILDTARINLFARILVHSLSVCSGWSDPELRLQWQGSDLVSIARGYKNFGLLRRHLIVLQATEMDVPVEYHFERQWVADWNLEWLFGTTVKALRGQPGLKDFKLQHVLDPSDEYFKAEELSLGSQDSVAKASDDVFWPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W865</accession>
    <name>A0ABR1W865_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667154.1">
        <property type="nucleotide sequence ID" value="XM_066811812.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044872"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="120" mass="11362" checksum="AC94D902B3548A1F" modified="2025-10-08" version="1">MCFGSSKRATGGYGSSQPTKVVHHHHGPEMGTAGYGGGHGMGGHHSGGAWEDTAAAALWAAVQAAVWGGGGGMLGGSSGGRMGGSGGSGGGMMGGLGKLAGFGKQGGMGGGDSLWDMALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9I3</accession>
    <name>A0ABR1W9I3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_007900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667557.1">
        <property type="nucleotide sequence ID" value="XM_066812215.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045275"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="565"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="139"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="217"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="236"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8080082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="849" mass="94498" checksum="AFB421823677333C" modified="2025-10-08" version="1">MVSDGRGTGDLDAQHRGTLTSFFQSRRLSLWPRRLSDGERRQRSPNFLDSGDEQSDDSIPAYEEEGDVRSDSDTQYSDAQSTFEFSLLDNGVDIPGTAASLNYLGETQTGEPTLGNPKKLDLPIAGLGDLGELVVIRKADDDSDEENEARLPSFQSRPAFHSLQSGSSKGKAVESQSAWSAATHPWATLGDYTEPVDEKQALRDEISRLRAELDALRNQSSDQLNRSRSLTEPSSHRQQSRSATSSRGSRRPRSKLKAMADDAAPSPTTLRELIMRQLLSPQIVSNAMANPHTDRQQARVTLDSPLTAPQIQEFTRLMNGMQLSGRNFKQPIALCAVCHLPKFKGSQKSNRSAYLSEVLTQLPGVTASAFEDFDPIWGVSTCCRRYVCKTCLTTAIIAGIGSQYWFELDKTSWIKCPVPVCGKSLPLDRNLDVLGILEALGVPDAISHVRRFERANQLRTALQALTPVPERNQLRRGKALHDRLIRYGRMSSPLDGATPRPVGQIELELLPIDTADGKGAIKIPIFKHLLPRQVSRTCVVCDEEYPEFHRGDEQRWKRVTKGYGGEWTWRILSFPTKEILSVCDHDHDICRECLSTFISTQIQSRGHGVVDNIICATPDCHHRYTHEEIRCLTTPDVFDTYDRYATINSVRDLPNFRGCLRDGCAGGGLYDGPDAAAEAPPELLLPSKDPNNIMCIECGLQMCFTCQTPWHKGLRCVEAAAQREHGDPHYGRTRDWLAQNTKACPGQGCGVQVAKGEGCFHMTCSRCRFEFCWECLADWSGILVRVPAEDGQGNEMLFRPEGHREGCYFRGEGALLPTQIMGNTLERGSGDCKEPRQMKRLLQIESPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9Q4</accession>
    <name>A0ABR1W9Q4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667704.1">
        <property type="nucleotide sequence ID" value="XM_066812362.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045422"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052988">
        <property type="entry name" value="Oryzine_lactonohydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064:SF2">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="234" mass="26136" checksum="71F5E1DC0DD947DF" modified="2025-10-08" version="1">MSQLGIVGRRGFPHLPQLHREQLAALNGTRDSNRDSLMYKFRPDATIEQLQVLPFQIHEAPCYIPEKSQLFSVEWGAPGGRNSEHDYQYLLDLKTSNLTTIRTNPPTRNLHGCVYCKGRLHVVADGGPHETEYLATIDPATWERTTILNNLEEQPFISLNDLDMDREGNYYMTNSLSGWGQYLHPCGAPTAPTVYFVNTTTMRIKTLLYLQNGNTSGVAVSADGGLLGTGRPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAC4</accession>
    <name>A0ABR1WAC4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666890.1">
        <property type="nucleotide sequence ID" value="XM_066811548.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044608"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="207" mass="22712" checksum="1C08BD67A779896E" modified="2025-10-08" version="1">MRFSVWRNGHLGCEPGTLFHRAKRLPSPTPLFLTCRQVYREAAVYVYDTPLIFHAWDAFRAFLARTRGVIPAGVASVQLVDSMPDGTFLGEREFLSCLQKLDLSSVGLRALGPVSSDQAQLLARAMWMGHLSRAKTVELFSPAAGHVGTVRFNGCPVTLRPDAAWARVLYLLEHDGEDEQIGELNSYAALVQAAEPLGLSIADSSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBG6</accession>
    <name>A0ABR1WBG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668325.1">
        <property type="nucleotide sequence ID" value="XM_066812983.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046043"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="46805" checksum="8DA1E7B06D439315" modified="2025-10-08" version="1">MAHADSLPSNPILHGRSTIEDEGLYAQPNSYERNGATGARRRREAEKALKRVCSHARPVAGSRNAAAKCIHRGWHRLLRTQGTGPLLLPATLGQRRPLKQLVPTCSGQQVAPFSNSVVTELRQPRVEAEPEELPSGHGDEASSSNILRRLGRNESYQIALQNLDQMRGNIVTYRYKLPNWLAGRDARQELFDTMEKAIASVVLKHPLMHVGLVGKDTTSPSWARLEEINLQNHIEWRLVTGGLQDFNEEFRAACSEQLDTKFDNYLTAPGWLVKIIHLDGSGFIEVLLNLNHTNMDGGSAKIFHKDLLQNLHDGQGSDPGLLLNKHILTLTDNSTATLSPPAENFVAFPVEAHHLDSFIQGSTLGADPSRAVQDAIPGHHDSERRACQAGGIMPPPSNDADRPPPRPGHGVPRAPSPSRPGPRPSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCV4</accession>
    <name>A0ABR1WCV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF924-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667821.1">
        <property type="nucleotide sequence ID" value="XM_066812479.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045539"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.320">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045279904" description="DUF924-domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="32786" checksum="A9AB644DB260927F" modified="2025-10-08" version="1">MPSDLPRPRTVVWLGLLPIILIAVYAAISHGGINNSSSSSPRNPDDIPDMAAPLRGFSLNPRVPSTTSGSAACPPAVGGTAPTKEMAMRWFAGGQEFDAQCQSAGAEALDSIGPHRLALPKFTTVQEDRAHYPDMARPFATQYGKDQDSAAAGKNALSIVLLLDQLSRNVYRKEQGPIYAHYDRLARAVSQDARARDVLAGPGFSDVQRYWLYMPLMHSEDLADHEAFDVYIREKIARAEEAGDAAAAGSLRNSLDFGERHMNIIRRFGRYPYRNKWLGRETTEEEAAYLEGGGETFGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDH3</accession>
    <name>A0ABR1WDH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667985.1">
        <property type="nucleotide sequence ID" value="XM_066812643.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045703"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="1">
        <location>
            <begin position="22"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="238" mass="25965" checksum="10BF5B232F5E6FE5" modified="2025-10-08" version="1">MKTYGFDASLPAKPVKNIGVVLFPSFDVVDVFGTLEPLNLLSLERQLNLYMIAATLDPVSTAPRAMNAFNSSFGEVIVPSHTFDSVIRDQSLDLDMLLVPGGIGTRAPDLNDTIQFVRDVFPRLQYLLAPCTGAGIAARAGVLDGRRATTNKRSWEETVAYGTKTYWVARARWARDGCVFTASGVTAAIDAVFAWIGHVWGEAVAADLALGIEYERHTDPSWDPFGEHYGRSDVPPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDJ6</accession>
    <name>A0ABR1WDJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668015.1">
        <property type="nucleotide sequence ID" value="XM_066812673.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045733"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="533" mass="58106" checksum="D781991099883E04" modified="2025-10-08" version="1">MTTDPTTPKHRTSMLSRRASSYQVLRSTPKLLTKLRSFSNGRALSSKATCRRYDLRERDTSGSSYGSPLAIRVSSRSGPPESRSCSSTEASYDPEPFLPLGYDGFYGEQVKINTRHPQRRVSLLRASAAIEVSGQLCRPYSVDYSRGFENAIHDNQCFLPVHHCEEGLSRYGYLYDIDIQVLPTAESVIIDVLNEPTSRVLGPGSSMLTLVQTHISASQPPHIDGKAHGDDPDGLMADLEYHLGNVQTEYIEVRLSYSHSGFPTFSDISGGAGASSSIVDGVSRSRTRLETRVTGVVTRNNPMSAWSPRPTPCAPVSNTLFAITAAHWGPIRANDIMHRIIASRSTPRKVAVTTATTTTPTTPKSPQHRHRRAGTDIHGGSDETVRAVVPPERTATAPPLQVPRRQTSLQKGALSPEPAKEGGGLPGKARKIWTEMRRTSSGSQPSYYVSSIKRIPGSSTESLLPGLSAKSGTPGEGSMGRQELLRDMAMHDVVPEPMFLSSIVPTPEEYYVGGRRMMQHSEEESPKAAINVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE73</accession>
    <name>A0ABR1WE73_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667878.1">
        <property type="nucleotide sequence ID" value="XM_066812536.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045596"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="114" mass="13050" checksum="D06312683772CD78" modified="2025-10-08" version="1">MDVDGTKLAWLHDRNPVTHSFTEFVRDATATKTNFRVLMSDTAEASIRRDRTVKQLCVIGCEYEVPWEEMYAIAPGARVVDDISLTMRFQGEPEWSVRVGLNTVEHDVNVQYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WF57</accession>
    <name>A0ABR1WF57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Succinyl-CoA:3-ketoacid-coenzyme A transferase</fullName>
            <ecNumber evidence="3">2.8.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008627</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate</text>
            <dbReference type="Rhea" id="RHEA:24564"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:35973"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.8.3.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Ketone metabolism; succinyl-CoA degradation; acetoacetyl-CoA from succinyl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 3-oxoacid CoA-transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.5" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668284.1">
        <property type="nucleotide sequence ID" value="XM_066812942.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046002"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.10">
        <property type="entry name" value="Glutaconate Coenzyme A-transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012792">
        <property type="entry name" value="3-oxoacid_CoA-transf_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014388">
        <property type="entry name" value="3-oxoacid_CoA-transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004164">
        <property type="entry name" value="CoA_transf_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02429">
        <property type="entry name" value="pcaI_scoA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707:SF60">
        <property type="entry name" value="ACETATE COA-TRANSFERASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="KETOACID-COENZYME A TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000858">
        <property type="entry name" value="SCOT-t"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01274">
        <property type="entry name" value="COA_TRANSF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="533" mass="56830" checksum="B0A4543D2F2708E6" modified="2025-10-08" version="1">MARPQTAVFLRASLQFSYRWATPSARQYAPLLQKWRRCYSTDKAGPVKKKRGGSKVFKSADEAISDIQDGSVILSAGFGLCGVAETLIQAIHKKGLKDLTAVSNNAGANDKGLALLTKDGRVTRMMLSYLGANKELERQYLSGEIALELCPQGTLAEKLRAAGAGIPAFYTATGGRTFIETGEIPTRFTPEGVLEEGRPKETRVFGGKSYIMETALPGDVAILRAWKVDEAGNCVFKYTTKTYAGLMAKAAKIAIVEAENIVPIGSIEPDSVDLPGIFIDRIVPATAPKNFENLKLAAPEESSSGSKEGTKTTLDSRNRIAKRAAQELQDGYYVNLGVGIPTLAASYVPEGVKVWLQSENGILGMGPYPATEEDADADLINAGKETTTLLPGAATFDSAESFAMIRGGHVDVSILGAFQVSASGDLANYMIPGKVFKGMGGAMDLVSNPEQTKIVVATEHVDKKGRPKIVQDCALPLTGKGVVSTVITDMAVFQVDRVKGGLTLTEVAEGVDVETVRENTDAEFEVAEDLGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFJ8</accession>
    <name>A0ABR1WFJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668343.1">
        <property type="nucleotide sequence ID" value="XM_066813001.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046061"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="260" mass="29957" checksum="092C91939E1A0133" modified="2025-10-08" version="1">MVTRTKRFRKFAKFPLEVQFLVFVQAVLNDHKDRIVAISCDTKRVFLTRDLKKPSGVFKTCSIALQAATAVYDQLVPLVGYNSFWPDTRTSTWPFDWPRPDGGITEEMRNLSIAQNDERVIGYIRVSTVHDIFLVSQWQHSFDDLRYSYPPKLMSVQLPPAVLSQIERVMEHENGEQTDEKEIQEPDSVRHSFDREVFSAARECVHVVEPTKQPDHLLLAQLVRDYTSQTALCLCPEPIICKGLLDTEEAEEENQEEQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL73</accession>
    <name>A0ABR1WL73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005552</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668790.1">
        <property type="nucleotide sequence ID" value="XM_066809867.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042927"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="470" mass="53021" checksum="93D633AD709B5E28" modified="2025-10-08" version="1">MRIDLFVPFDLGRAIARNDSRNCRKAIKAAPHQVQERLQKLQEKEGQGVIPERLTASRCIECVSQLTYVPKCGEERPRCRNCSRRGSPCDLADDSAVPDAPARHPAVSPPAPTPDRLGGQTTNGGAGLGTLTVLDLELLHHYTTSTGPTLSSDPVTRHYYLVDVPKLGFCHPHVLYSILALAASHLGHFRPESRQYYYAEAAARHTAATSIAAPLLSNISVQDSVPMYCFSSLTLFISFANLKDDDHFFDASNVIPSWLTLFRGLRTILEANGRAMLSSSIAFLFRPNGHINDKGDPQQQQQQPDHEALREFQNHLEICTSEEEPTRQHLLAAFGDLRSAFSSFDAKEPGHEDKTRSIFTWLYKIPDGYIDLLRQKNSDALCILAFFCVLLHKLEYHWWLKGWGVHLIDRIYTAVDDAHHAWMRWPIQEIGWVPPRRGGRFQASIRSQHRLHELGDKRFDSVAAYEARVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLU4</accession>
    <name>A0ABR1WLU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005684</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668922.1">
        <property type="nucleotide sequence ID" value="XM_066809999.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043059"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057082">
        <property type="entry name" value="PH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057081">
        <property type="entry name" value="PH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23076">
        <property type="entry name" value="PH_FT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23074">
        <property type="entry name" value="PH_FT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="238"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="356"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="490" mass="57121" checksum="B7BDD9842CDDBD59" modified="2025-10-08" version="1">MDMITRDVGSSLLNGCCHEAERARLVGLSLDGLCLTLPEKFHAHLKGLIQQIQLCSQMLLTIADLSQLHITRVPVVTDYLNVILPCFSRSLRDITEYVNNRSLDKEHRWRKMYHAMGEELPGTPLPARFALYYAFLDMLKHLLTKSPEFDLNGLEVLRLRIFQLREARGIPPPSPIHQDQIVRQQKAMAFWEQETNTHWAEDIFTRPLPSRTEFKRNNRFFSRAYGPFRRLGAIDMLSDVKTLAKRTFDDDTVSVTFFLQGLEEIPTLMVRQIHSGEPWAAIKGAHELCIKRDFDSRLTFTRWSVTERRIKPWAQLTFITWEEMVLFYCTFVCLKVRSPMFINIREEEYEIRKEAKLFQAQIFDDGFYHCLKVYEDILTKRRRLHASVWEGDLKGCPIWTAFLPEKKGPLRSWLLRKTSHVVAIRDVSPYVFCNNYRANTTDPRQSKFHALELEFTHTTGAKRFKELFEEQAPPPSATSSDHDTKSSGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLW6</accession>
    <name>A0ABR1WLW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Condensin complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_005781</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CND1 (condensin subunit 1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669019.1">
        <property type="nucleotide sequence ID" value="XM_066810096.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043156"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032682">
        <property type="entry name" value="Cnd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007673">
        <property type="entry name" value="Condensin_cplx_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024324">
        <property type="entry name" value="Condensin_cplx_su1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF2">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12717">
        <property type="entry name" value="Cnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12922">
        <property type="entry name" value="Cnd1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017127">
        <property type="entry name" value="Condensin_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="6 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin complex subunit 1 N-terminal" evidence="13">
        <location>
            <begin position="99"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="1052"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="488"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="930"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8084510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1235" mass="137226" checksum="F0E08E827A32CD2E" modified="2025-10-08" version="1">MDAINFDINDALKHYMSDPASVATPEADSALVDCENDPESSPTPAAYFDSLQFLLKCAPSSPNISFVRDASNRPSAYQLQGSTSELFVRSRCTQFLPTHALSKIFDLIMSGLAAEADAINHDLESPDEQEIIAHHKTLLEVYGFLLQWAIACVETKAAEKSSAAPVSRARGKGAKAKAAAGKDKDGNWDSAAQLQIALDVMSKVLKLKLGKIFLTTSERDTFIGLLTRPVYMILESEQRTKNTAIRMHGFKVLCIAVKHHGHGYAAQISIVQNLTYFEHLSEPMAEFLHILAEQYDYPQLADESLRELSNKEFSTNDTRGPKSVSSFIVKLSELAPRLVIKQMTMLAKQLDSESYTLRCSLIEVCGNMIAYLSRQEERGDNHKSQLNAFFDVLEERFLDINPYSRCRAIQVYTRLCDLDQKFPKRRQRAAELAARSLEDKSSHVRRNAIKLLGTLVKTHPFTVLHGAQLSRKDWQERLDKVDAELDALQPPAGEPGLGDGQGDTTNAALVDEPTQLESPQKPREPKEMTEEEKAAIVRKAQEDAATSEAIEKLTLTKRYYTDALKFIEVLQESTPTVCQLLGSKNKSEVIEAMDYLEIGNAYNIEDNMVGIRRMLRLIWTKGNSDEGKGVQTHLIDCYKRLFFEAPDSFSQNDAAIYIARNMISLTSGTTPAELTSLEQLLATMMKGGMISDVVIQKLWEVYGYQKREISRSQRRGAIIVLGMLASANPEIVVGEMETMLRTGLGAHGRSDHQLAKYTCIALRRLNPTGRQAKDSPVKFSRLPTDHAVLGKLAAITDVQSDRKEWFGVAEQAINAIYAIAKHPDALCGEIIKHKTKSVFALQRAASTSRPGSRDMDATMTNAAPDPQGLTTALNEPTQAVNQPTPEPAVEPKQKAAIALSQLLFIVGHVAIKQIVHLEMCELDFKRRKQEKEKTAEAEPEVAAPKSKGRKSKTPAPEEGDELDLIGGTTEDDFTEAMAHIRERELLFGPQSLLANFGPMVAEICSRSDIYRDKGLQAAATLCLAKLMCVSSEYCEAHLPLLITIMERSPDATVRSNVVIALGDMAVCFNHLIDENTDFLYRRLADPDLSVKRTCLMTLTFLILAGQVKVKGQLGEMAKCLEDSDKRIADLARMFFTELSTKDNAVYNHFVDMFSLLSAGNLEEESFKRVVKFLLGFVEKDKHARQLADKLAARLPRCDTERQWNDVAFALGQLQHKNEEITKVVGEGFKIMPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM01</accession>
    <name>A0ABR1WM01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DnaJ like subfamily A member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005835</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669073.1">
        <property type="nucleotide sequence ID" value="XM_066810150.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043210"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051964">
        <property type="entry name" value="Chaperone_stress_response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054076">
        <property type="entry name" value="ZUO1-like_ZHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21884">
        <property type="entry name" value="ZUO1-like_ZHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="22"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="504"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="354"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="524"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="298"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="479"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="549" mass="61103" checksum="319519C3DB577C05" modified="2025-10-08" version="1">MGAGPSTERGSATASAEPKKVDYYELLAVDRLATDDEIKKAYRKKALELHPDRNYGDVENATKKFAEVQSAYEVLSDPQERAWYDSHRDAILRGDDPSADGATPEYYNVRMTTTEELYSLIRKFNSSVPFTDAPDGFFGILQETFDSLSQQEVAACEWDGLPIVEYPSFGKANDDYDTVAKPFYSAWSNFATRKTFSWKDKWRLSDAPDRRVRRLMEKENKKAREDAVQEFNETVRSMVAFVRKRDPRYIPNTQTEAERQKVLRDASAAQAARSRAAHQEKMSEYVVPDWAQSRGDDNGLEGEFTESEEESEVEHIECVVCNKIFKTEKQFEAHEKSKKHIKAVQQLRREMKKENAGLELDTPPTSTQHATPMSEEEGGEAEDGEGIADDANDAQIPPATGSGPAEKVASVDIPAAVTPETKSEDDDDDDDDDYAPRSAVEERLASGTESKALQDDNVDELSNQAEDMTLDDAAAATKKMGKAKAKREKKAAKQAALEQQGAAHQCMVCNEAFDSKTKLFAHLKDSGHAAPPPQAKVASKPSKSGKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMC3</accession>
    <name>A0ABR1WMC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669087.1">
        <property type="nucleotide sequence ID" value="XM_066810164.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043224"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="62" mass="7138" checksum="757FEBC085970FCF" modified="2025-10-08" version="1">MHTVQEAYKKLASCESQDPDIECPSSLCMYVGNPRKPTKSECDDCREIREVLESLEEDNEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMU0</accession>
    <name>A0ABR1WMU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trehalase</fullName>
            <ecNumber evidence="5">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006095</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669333.1">
        <property type="nucleotide sequence ID" value="XM_066810410.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043470"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011120">
        <property type="entry name" value="Trehalase_Ca-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF6">
        <property type="entry name" value="CYTOSOLIC NEUTRAL TREHALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07492">
        <property type="entry name" value="Trehalase_Ca-bi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00927">
        <property type="entry name" value="TREHALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neutral trehalase Ca2+ binding" evidence="7">
        <location>
            <begin position="102"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="754" mass="87139" checksum="815EB93ECBE7071B" modified="2025-10-08" version="1">MAPTKDDLLMPLPAAPVVRQRRQDGSFSSIDEASVYEDAKTYYSAEARDSGRHHARARTYSQNGLEQQMERLGLVEPHRRGSHDESSRPHQRQFLVDVDHTLESLQAQEDTDNNMQITIEDSGPKVISLRTAASGGHNRFDIRGTYMLSNLLQELYMAKEFGRKQVILDIGRLNENPVNRLSRLIKDQFWERLTRRIDASTVEIAAKDPKDWTDDPRPRIYVPPGAPAQLEFYQKVARDRPEMRLDVVELPAKITPEMVVHMNDKPGLLAVAMEDYVDPKTGEKTLRGLPFVVPGGRFNELYGWDSYMESLGLLVNDKVHLAKSMVQNFCFCIRHYGKILNATRSYYLCRSQPPFLTDMTLRVYEKIKHEPGATEFLRTSFLAAIKEYYCVWMSEPRLDPKTGLSRYRPEGRGVPPETEASHFVHILEPYAKKHGMSFKEFVRAYNHQEVSEPELDDYFLHDRAVRESGHDTSYRLERVCADLATVDLNSLIYKYEMDIARIIRQVFGDKLEIPAEWCDGPMKPGQIETSAIWDRRWKRRRAAIHKYLWNDEKGMYFDYDTHKQEQCTYETCTTFWPLWAGVPDPDRAAKVVKNAVPMFEAYGGLLSGTEESRGAVSLERPNRQWDYPYGWAPQQMLAWTGLYRYGYQDLAQRLAYRWLFMVTKAFFDFNGVVVEKYDVTRPVDPHRVDAEYGNQGSDFKGVAKEGFGWVNASYVYGLGFVNTEMKRALGTLTPWDSYEKAQQLKEEKILSDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP38</accession>
    <name>A0ABR1WP38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669808.1">
        <property type="nucleotide sequence ID" value="XM_066810885.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043945"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051019">
        <property type="entry name" value="VLCFA-Steroid_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899:SF13">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="39975" checksum="67216250E2646E80" modified="2025-10-08" version="1">MLTTILTLVGLVWTLSTLSGAVKLVRLYLLTPSKLHRYVYHSSTSNSSVRDEKEQQKEPWAVVTGASDGIGRVLAQELATAGLNVVLHGRNTTKLEKVQAELKKAHPARSFRLLVADASLVRGATSLSTGAGSGGDHDKGQLLGLDVEAMTKKELDGLHITVLVNNVGGGVKNPLMGDFLEYSPRQNAEAVSKESLFAMHLTHALLPQLRKNRPGGALIISVGSMADVGMPLTAMYSACKAFNKALFETLALEDRLARIDDRKGNGDERSNVEIMYVRLGDVTDVSWRRGAGTLTMPDSRTAARAILARVGCGKSVVTAYWTHELIRVSTGALPDWLLERLLLSIMSGWRASVERNGGDASASIVGNGFFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP44</accession>
    <name>A0ABR1WP44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NIMA interactive protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006513</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ADIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669751.1">
        <property type="nucleotide sequence ID" value="XM_066810828.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043888"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021622">
        <property type="entry name" value="Afadin/alpha-actinin-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11559">
        <property type="entry name" value="ADIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="359"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="503"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="617"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="628"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="655"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="698"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="734"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="778"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="815"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="864"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="907"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="946" mass="103733" checksum="F9BBACF2BAAFEEEA" modified="2025-10-08" version="1">MIESDNLRTASLYINNQLLSRGLLRDGQNIDFADPDDAPGGLQDTMGRIMGVVNDLILRRDRDAAHRESLSTTLLSLRADAQRNAAEAARQADKFADTQRKLDGAEATERALRLQLKSTESSVFKLKDEVSKMKATVAQNRAACANDVRRRDRQIDSLKRAVVDAGRVRGGNKNRDVVSITVVNEVGVEEKPNGVSYGGTDEDGYSLRMETNEFLTELAKGLCEENSTLLHLLRRTVGRLREMSGIEAENAKSDPNGGDATAAAPKNADEMADELEDIMMHLRSLLTNPSFVPIEEVEVREVEIHRLREGWEQMESRWKDAVSMIEGWRKRMAASGKSVNMEELQMGLRLSPVRVRKTEGRYDNRDQHQELSCVQEEDEEEEEEEEAGDDETDSQNSQIRHERPESPSPKESLHLVPAPRYDENGGSDLDSDQSSIFHDDVDDEEDEEPNVQILHASTATTIDSPPLPAAPQLSPLKNSPSSGNRRSGNGSRRTRPGDFTTIVEEKTWEIRAVTDDEPPAPPPHGAKTQSPKASLVLSPPQPKDLLRPNSTTSYDSPLFGTSIESPLRKQPNRKLFDQSRPGSRETTPEREVKPEPKAGCKSAQKKKSGTKPPKPASRPASRAATPELESKPEPKEAPKSAQKKKSGTKPPKPASRPASRPASRAASPDLEPEQEPKEASKSVQKKKNATEQDMSTSPDATAKPAPPAKAAVQPAKRTASAPSATTKKDAKPANTLTRSKSTTNTSKSRARSPPNTKNKRSRSPNTAKVARDRSPVRLNPPNPPNPPPSSSRLPRRNPPPQSPLTMASIAAKLAASEREADAARVRAKLKAARMGRGAPNQNQADGAPSQAVIPEDPDVSLGDPVKKDVPIFEIEVSKESVSKDGDVAEDDGEEPPPTPKELDIEKRTRRITRRTSKAVSRRRSTLNPWELESLIQGNLEVDSPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ15</accession>
    <name>A0ABR1WQ15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670112.1">
        <property type="nucleotide sequence ID" value="XM_066811189.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044249"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="9844" checksum="7D367368D1D70802" modified="2025-10-08" version="1">MVKKSSVSDAWEDDWESQADKEAKEPAATAPPAPLTKKERLAQHAELNRKIWETADTPGNGVPLQFLASTPTPPLAQPFKPPMTVLARNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ66</accession>
    <name>A0ABR1WQ66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669129.1">
        <property type="nucleotide sequence ID" value="XM_066810206.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043266"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="115" mass="12723" checksum="EFA9D24284F9AC75" modified="2025-10-08" version="1">MFTIGNAATNQAFNHSGAAVDPTSPLYKELAAKYNYAEDTNFQDFIRSKIMEMAAKEAREKEEKQGRALSSSNNNNNNNGINGGDADVVPRGTTKEPKKKSRRSLRKALGLFFCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQA0</accession>
    <name>A0ABR1WQA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669159.1">
        <property type="nucleotide sequence ID" value="XM_066810236.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043296"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="125" mass="13304" checksum="C04B005559711653" modified="2025-10-08" version="1">MLEVPKRESATAIEYIESNTRKLRSLFKSPTKTTQSLPTKGKSAAETTATIRAEASMAVPGLAATAVSPRGSSRMSTLEDRIRTEEGPAEFGSSQSLDPLELNQDILSILDDGADFTEVTQGAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQB9</accession>
    <name>A0ABR1WQB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670243.1">
        <property type="nucleotide sequence ID" value="XM_066811320.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044380"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF13">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="255" mass="28004" checksum="BC1D1D141E2E904E" modified="2025-10-08" version="1">MASSKPIILIVHGAWHLPCMYDPLKHELNKLGYTFLCPELKTVGADKHGVTWEADKEMILDLVEPFFDQGKEIIIIGHSYGGIPACAATEGNGVQDRAAAGKKGGFRRIVYLAGFAILQRGMTLLQAFGGEWAEWHDAAVPNPGDQLTLVNEKAKDALFNDFPDEAERDAWLAKLVPMSQDAMETPVDFVVADITIPKTYVICELDRALPVALQEKLVESMPGFRTERIRAGHSPFVGKAKECADLIAKIAEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQE6</accession>
    <name>A0ABR1WQE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669204.1">
        <property type="nucleotide sequence ID" value="XM_066810281.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043341"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="343" mass="39369" checksum="5ECD0B4DCA191335" modified="2025-10-08" version="1">MALFHGRRIRSRDLGGGFRYNAEDFSVSEPAKIDFNGMDEQSQCVLFCSIPSEIRTLIFEYALAPHDNLAKPYAKDRMYCRPGQLYHPKTDISLLQTCKRVFQEARVLPVALATHTFWLFGGPWRCMKTGLKGMTRFSAWQDSMSEEQRAAVDCVQIFAQQTFLESLGTQSNNGLESLTFAARTLRITLRHTDWWSWESPPASSDRLGICPWERGRTSHQKMLSLPLEHTPEAMRELMRPGTWGWQVCRVQNLQTLEMEFEIDERKKSQLDAVLERARHWIFPMSDGDGVLRQSGAVAHSTYDGFVRNKDDSTPVLSPTGSHHNPWVDRTFHVAIKTWKRSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQG7</accession>
    <name>A0ABR1WQG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trichothecene 3-O-acetyltransferase-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007051</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670289.1">
        <property type="nucleotide sequence ID" value="XM_066811366.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044426"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051283">
        <property type="entry name" value="Sec_Metabolite_Acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054710">
        <property type="entry name" value="Tri101-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896:SF64">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22664">
        <property type="entry name" value="TRI-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Trichothecene 3-O-acetyltransferase-like N-terminal" evidence="3">
        <location>
            <begin position="46"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="335"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="480" mass="52225" checksum="69DF023B8AAA4C7F" modified="2025-10-08" version="1">MANSIPSRVIHVKPQEVTTSNRGQIRDNGDEIFQVSDTGHQIISMWVKLVDIFELPEGSNQDQIVTNLTKGLEKAVGDHPELTGTMHFDNEAKRIVIKRAKEGSVALHIKDATAAEDQIPSYAWYHEQDYPVHRLEIEHLIPAEAAGHPMHVAKDVDTPGPPVAAFQATFIKGGVIIATSVSHQVCDGLGWDSFNSTWAAYSKAATTGKPATLDTNIPPHDYFIAKTKPTPEEWEALRGKYPTMQYRTDPAPPPPADFVMPEVKTRVFHFPRSKLAALKAECGRGLPEGAYVSTYDAVAALWWRAMLRAKRPLLNFGDDEASKCIHAVNMRKRADPPLPPALHRHGGGAALVRDGDDRAGHGPAGGGAAAAGADSPGQHGVGHARVHRGPDEVGGGGPDLRFNELNMPWVLGKDCMGFAWHDMTPYQTHDYGFGPPTGFRWPQMGFESFFFMLPTRAGMGGKGPTRGSRSRELLPALGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQV4</accession>
    <name>A0ABR1WQV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD/NADP octopine/nopaline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668978.1">
        <property type="nucleotide sequence ID" value="XM_066810055.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043115"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051729">
        <property type="entry name" value="Opine/Lysopine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003421">
        <property type="entry name" value="Opine_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38015">
        <property type="entry name" value="BLR6086 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38015:SF1">
        <property type="entry name" value="OPINE DEHYDROGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02317">
        <property type="entry name" value="Octopine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal" evidence="3">
        <location>
            <begin position="7"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Opine dehydrogenase" evidence="4">
        <location>
            <begin position="181"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="366" mass="40012" checksum="2FF86469B0256F9B" modified="2025-10-08" version="1">MEFQQYVSIIGAGPAGFALAADLLSHGKNVLLYSHPTHLRHANSVREKGCLKACGVMEGFANIPITTDMAEVVAFSQVIFLTVPSTGQDTILQEMKAYDLSQHILIAVPGNLLSLIKDAGMEVGNILETNLSPYSCRMDEGQLLVLGRKKRIMIAALRNHDLDPSFYDAVQDLFPGVRLRWCSSVVEVCLSNINGVFHPLMMLMNAGRIESTGGDFLLYRDGLTPAVANAMLGVDKVRMDIGAALGLCLQSTIEVSNECYDQSFTSLVTLAQKSPPHNRLKAPSDFGNRNISEDVPDLLVPWCGLAEVLGIDASPIAAVIVLAEMTTGESFMETGRNMRRLHLDTVSRRELVARFSPPMTQYESRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WR71</accession>
    <name>A0ABR1WR71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669022.1">
        <property type="nucleotide sequence ID" value="XM_066810099.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043159"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="362" mass="41985" checksum="0C75AEB907A3A70E" modified="2025-10-08" version="1">MATRHLDHDTGLVYYEHQFRPQIFSHKYWDKKPIKRARRPRRKSKGPRSLMDMAMTAIGDNLSLLSPEALRESPEMLIWRTWDHFYDEGRLLNFHGWKTFLDTLAGKKHPEKQTDPSRKRSASTVFPLPNPRPPLALFLTPLRSPAATFLVRLTISHGASFEKNEMLALAGLENLCTLSIISPELDPTTCTFPRVDDRLVREWSLLRRPFPSLRALRIWGNDFTTFRSLEHVLAFPVLEVYNVAGKYTDWNSRKLDGRYQCLWIRDQPEDPDQPIEAAFGKVSKPYVTMFLGDVDEVKYRAISPTLRYEICNTYVRNEHAPRLDEARRVSKRPIHSVSNPAAASKHKRHLNINQVLAQFLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRN4</accession>
    <name>A0ABR1WRN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aryl-alcohol dehydrogenase Aad14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006567</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669805.1">
        <property type="nucleotide sequence ID" value="XM_066810882.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043942"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF2">
        <property type="entry name" value="ARYL-ALCOHOL DEHYDROGENASE AAD10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="34"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="359" mass="39576" checksum="2A3F65469BEDB363" modified="2025-10-08" version="1">MTSLSRILALAPEPPTELGRLRVLSPNAAVRVSPLQLGAMSIGDAWSDVMGSMDKTSAFALLDAFVEAGGNFIDTANSYQDEQSETWIGEWMRARGNRDSLVLATKYTSDYRSHALGKGTGAANHTGNSRRALHVSVRDSMAKLGTDYLDILYLHWWDHTTSIKEIMDSLHILVEQGKVLYLGISDTPAWVVSAANTIYQGRWNVILRDMERDIIPMARMFGMALAPWDVLGGGKFQTKAELERRKNAGEGLRKLYNEGEQTEDEVKMSEALAKVAAEHGTDSVTAIALAYIEHLKQNIAALSIRLTEEQIRYLESVKPFDVGFPHDMLGPDPNITGSSARLNRAGNVDFPQARQPSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS24</accession>
    <name>A0ABR1WS24_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669892.1">
        <property type="nucleotide sequence ID" value="XM_066810969.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044029"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039470">
        <property type="entry name" value="Nuc_deoxyri_tr2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15891">
        <property type="entry name" value="Nuc_deoxyri_tr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="167" mass="17811" checksum="399BE6D83EBEB7F6" modified="2025-10-08" version="1">MSPVTTAQIVQAPAPDPAPIHPHTVFLAGTTTAANDGSGDWRDALCTALSAHPITFYNPLRSDWDASWRNDATRADLVVVYLSPHTDAPVSLLELGLVAGLAAAAAMTAANGDQEDGKKKTKKQVLVCAHEGYKKRGNVQLLCQKFGIEMVDTTADFPSAILRMLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS85</accession>
    <name>A0ABR1WS85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670132.1">
        <property type="nucleotide sequence ID" value="XM_066811209.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044269"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="384" mass="40456" checksum="15D3C9DFD0917C5A" modified="2025-10-08" version="1" fragment="single">ANSKEAADEGPTRKRPMSKGARSHFSEASFGSLDELNSAAPEPSRKNRRKSSKGVVGGILGKMSAPNNVTSGPSAAATDNRNRNVWANHIKNGDDRTHVPPMGRKVFIIRIVQLVLAVVFLVLAAFAAFTLNMGNVSVSIIFRLLLDRGLFPVARRVDTLLSRSLSLDRPYVSARHTPPSPYSSAATPRPPFTRVIEGLTNVFWLATWASLASLASALNVARAGYYYVLAARQTPGPGAYQPQPPPPPPPHEIGVPPDGGRGPGGAGAGADAGASSAAAAATARSTIQAAKVAICVDAGLGALIWVLFVITLIATSESFPSLYLAYLTFPAYLCASLLPPPSLPYRLTAPTDTTRRHVHYKPPEEQQGRQEGQRAGGSGGVGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWW3</accession>
    <name>A0ABR1WWW3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670547.1">
        <property type="nucleotide sequence ID" value="XM_066806929.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039989"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="24048" checksum="D328A5CEAE4EA65B" modified="2025-10-08" version="1">MYSHDETVEALSSYLKLLDRVHSGPECLQFPPQGGWPQITKSGFACLGITDETLELLRHVPQWETRCLDFMPRLSLDSYIDPRLVAAWNENSERLRGGEENVPTSRVPPRLVLLGSNQEAEEYYYKVYIDTKHGAVLMEQNAGNIWPELGIPQCKDEVKRDADVLPGPDPWGPDEMEYAYYRIQPFFAACEQKAALARVVPGLRGPQRLSVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXN6</accession>
    <name>A0ABR1WXN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002849</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670782.1">
        <property type="nucleotide sequence ID" value="XM_066807164.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040224"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052649">
        <property type="entry name" value="NCE102-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28165:SF2">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28165">
        <property type="entry name" value="NON-CLASSICAL EXPORT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="178" mass="18306" checksum="D6E485CF490C7655" modified="2025-10-08" version="1" fragment="single">LICGAVVFGLSVSLANQQRVGSAPPEIGFSSFAGGFAIVTCLVGAAGLWVDSIPGIVTMVMDGIAAVVYLVGGIILTSALKSVSSCTGTSDDEIIARGYNKVLNFGCPTMDSTPTPACADLMVTDSDLSADPTIPRCQRAITDYSFDFVGLALCVVMVFLGYVLARRGGSRPTVAAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYX8</accession>
    <name>A0ABR1WYX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-ketoglutarate-dependent sulfonate dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671218.1">
        <property type="nucleotide sequence ID" value="XM_066807600.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040660"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009836">
        <property type="entry name" value="GRDP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365">
        <property type="entry name" value="ENOLASE (DUF1399)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365:SF7">
        <property type="entry name" value="GLYCINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07173">
        <property type="entry name" value="GRDP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="650"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="773" mass="86584" checksum="0BB10447744A32BD" modified="2025-10-08" version="1">MSGKRLRKVEGSGIGSVYVPPAYTDYEGPQIDEETESQLRAAFYNLNLGCDASPTPVVDTCLAHLKLLRAFEELKSRTGLTDGLWDIWDSRAQNASRGGPLDILVKLREKRWAVYVARAVDRYEAWWKSFVPAMLTEFDMVADGKDGQLSRFESFTSKREPMIWTSSSLPPLGNANPFVASRAVTVTNQTVATDVLLVWHAHMLNPRTFLEDCLRWGYGHLWHSGMPWTEINAALRPDFEYEVTEDCKQSWTHRTGLAWSNRDDPDIKPLRCPVCFDWETYPWTTCGLPRDYKGDKKPGLVGSGLGDGQLKSECARCGITIDEDLLRVAKFRDDVENLVTHDWPMAGTILDVRDGLVRKQQKDPDQLFPNRLVRRGLLVDVTNIFQPGNKVKPSMSVIRDRIEKITSHTSLRHSSDLLKKIDKNIDGVGTLAPHRLSKQARMQTRCMMSRYWENSSIFGIDLRGAVMRQGVFMEKMYKIDWLHSPTARFTMEKLVVKYERFFDIAAKFLDEFVTPTLDVDLAWHTHQLSPSQYFDYSVAKTKIFIDHNDKVDEEKLAESFDWMVKTYQQRYGEVYSECFCWFCESLRFKHASSMKKLSPEWRVAVQEGNGESVHISSHPAVQAENEHNPGRRTRRLVFHNDVDDAYSKALKKTNQSPKKALFGRTKSGSSSSSSSTTIMGPRGEDHCDHWGKSIALPGPWFSEPVATLTPQMYPSHPGLIHTAPGQPGACAAGTCGGSAGCGSGALALCGSGCSGMGRNIFGSAGCAGGSSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZF7</accession>
    <name>A0ABR1WZF7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003477</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671410.1">
        <property type="nucleotide sequence ID" value="XM_066807792.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040852"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713:SF3">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="439" mass="47100" checksum="4145FDF6C89EFBC1" modified="2025-10-08" version="1">MEQIQEAYDALAIEFAASNPKSKAAYDIATKCLPGGNTRTVLFYEPFPLYTERAEGCHLWDVDGHKYVDLLGEYTAGLYGHSNPVILKAIQEALKRGLSFGSHHADEARLAQLIRDRFSGIELVRFTNSGTEATLMALAAAKIFTDRSKIMVFEGGYHGGGFLFKSGPHPVNVPHQFLMAQYNDTASVDELIAANGEDIAAIIVEPMIGSGGCIPGTPGFLAHLREKATEIGAVLIFDEVMTSRLYSGGGVQSELGITPDLTTLGKYIGGGMSFGAFGGKADIMSTYDPRATSTARKGASVPHAGTFNNNVLTMAAGSAGLENVFSPDVARTLHGRGDDLRNKLNSIAKGTILKVTGCGSIMNIRFIATPPEDIHNVRDLEGQSTLLLDMLHLYMLGQGFYMARRGFIALSLELTATELDGFLEAAQGFLRKYATLVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZL9</accession>
    <name>A0ABR1WZL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Pyruvate carboxylase</fullName>
            <ecNumber evidence="3 10">6.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_003536</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>hydrogencarbonate + pyruvate + ATP = oxaloacetate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.1" evidence="3 10"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671469.1">
        <property type="nucleotide sequence ID" value="XM_066807851.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040911"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07937">
        <property type="entry name" value="DRE_TIM_PC_TC_5S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055268">
        <property type="entry name" value="PCB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005930">
        <property type="entry name" value="Pyruv_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009554">
        <property type="entry name" value="PRK12999.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01235">
        <property type="entry name" value="pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43778">
        <property type="entry name" value="PYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43778:SF2">
        <property type="entry name" value="PYRUVATE CARBOXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001594">
        <property type="entry name" value="Pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89000">
        <property type="entry name" value="post-HMGL domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0092">Biotin</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="14">
        <location>
            <begin position="47"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="13">
        <location>
            <begin position="169"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="15">
        <location>
            <begin position="585"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="1106"/>
            <end position="1181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8088575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1183" mass="129431" checksum="F5537A0B2D2062F7" modified="2025-10-08" version="1">MAELPDLKDLKAGGPEGAVDEDVFEEGMAPKEAQTVHHIRANSSIMQLKKLLVANRGEIPIRIFRTAHELSLHTIAVFSYEDRLSMHRQKADEAYVIGKRGQYTPVGAYLAGDEIIKIALEHGAQMIHPGYGFLSENAEFARNVEKNGLIFVGPSPDVIDSLGDKVSARTLALKANVPVVPGTEGAVATFEEVKSFTDEYGFPIIIKAAYGGGGRGMRVVRDQASLKESFERAVSEAKSSFGNGTVFVERFLDKPKHIEVQLLGDNHGNIVHLFERDCSVQRRHQKVVEIAPAKDLPAATRDAILNDAVKLAKSVNYRNAGTAEFLVDQQNRYYFIEINPRIQVEHTITEEITGIDIVAAQIQIAAGATLQQLGLTQDRISTRGFAIQCRITTEDPAKQFQPDTGKIEVYRSAGGNGVRLDGGNGFAGAVITPYYDSMLVKCTCLGSTYEIARRKILRALVEFRIRGVKTNIPFLASLLTHPTFIDGNCWTTFIDDTPQLFDLIGSQNRAQKLLAYLGDLAVNGSSIKGQVGEPKLKSDIIIPELFNDDGSKLDVSQPCQKGWRNILLEQGPKAFAKAVRDYKGTLLMDTTWRDAHQSLLATRVRTVDLLGIAKETSHALSNLYSLECWGGATFDMRKLVPNIPFQMLLRGANGVAYASLPDNAIDHFVKQAKDNGVDIFRVFDALNDVEQIKVGAAAVRKAGGVLEATICISGDMLNPKKKYNLDYYMDLAAKLVEIDIDILALKDMAGCLKPYAATLLVGSLRKKYPDLPIHVHTHDSAGTGVASMVACAHAGADAVDAATDSLSGMTSQPSINAIIASLQGSDFEPGLNPAHVRALDAYWAQLRLLYSPFEAHLAGPDPEVYEHEIPGGQLTNMMFQAQQLGLGSQWAETKKAYEHANELLGDIVKVTPTSKVVGDLAQFMVSNKLSSQDVIDRAEELDFPGSVLEFLEGMMGQPYGGFPEPLRSKALRNRRKFDKRPGLYLDPIDFKKVRTEIGQKWGTVTECDVASHVMYPKVFEDYKKFIQKYGDLSVLPTKYFLTAPKIGEEFHVELEKGKVLILKLLAVGPLSENTGQREVFYEVNGEVRQVSIVDQKSSVENVSRPKVDPTDSSQVGAPMAGVLVELRVKEGSEVLKGSPIAVLSAMKMEMVISAPHNGKVSGLEVKEGDSVDGSDLVCKITKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZU5</accession>
    <name>A0ABR1WZU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Binuclear zinc transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003612</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671545.1">
        <property type="nucleotide sequence ID" value="XM_066807927.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040987"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF10">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="615"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="666"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="699"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="742"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="762"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="773"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="875" mass="96419" checksum="27326753B2F1ECCE" modified="2025-10-08" version="1">MPPPIVVGDDTPDCHEQTTEALACVTCRARKLKCNRVKPACSRCVRVKGDCVYPESRRKPAFKRRNVKELEARLAQVEILLKDVGTEKTSSPEKAEKEKFDEAIAEFGFPEVSQSQSDDVFFQGMDYNIPPTSTSGDACNMYSFNFSAEPTGEFGTASDFFGGELLGLGISEPTPPFEVMEELHQTFFQRQSETIPILNQQRYLQEFYSPPHMKPPMCLQYAIWAIAAIENNKYSASRDVFYQRARQYAEADEMKVSHANQLPQRQVLCTDFILGAWRTFSHSETCPGMGLYCMRLAEMMGLQRLDCPPGEMPPAILPPKDWIDLEERRRTFWGIFCLDSHCSISTGWPTFVDPSEVTTHLPCSEAAFRNGEEAESCTLNEALKGYPYSSFASSVVICHFFNEILKHVHRPRPDDFPENYEFGRYWTRHRDLDSTLSSAFMFLPEGFRLPDNYRDRTAVHTNLNLHASIICLHHAAIDKIDKHKLPNHLKKASHTRLLTAAQEIVNIMKTINTTKSHPKTALAALSLYSAASVYIYHCKETGVSGAVDNLNYIVSTMSELSQDHYITRAFLRQVAADIECNHLESYVKIPKLSDLPSHFANGDCHIPLVVRSSVSRHHETPPVPGKVPPRKPTAGMMGKSPGLSGDCGVACLNGGVRDTVREIVQSIPGDHASHKRKRQAPDRSPTEGTSDLDDGSPLWAQSGSLGYPESFSSNSTPPDSNMNSAATESCRPQDLNLEAPSLQGNGPNSCTQSLFPMPSLPHRTNSPSVAGPTQTTSSSSSRTNSGGITLGPTIIGSRRMPSTLNTTGPEHGPTLPGGVSTWEMAGHCMYSQFQNGVAPGASTTDVASWNFLGMTDQIDWGTGTGVAADTANATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZZ2</accession>
    <name>A0ABR1WZZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7582 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671600.1">
        <property type="nucleotide sequence ID" value="XM_066807982.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041042"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056004">
        <property type="entry name" value="DUF7582"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24483">
        <property type="entry name" value="DUF7582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7582" evidence="2">
        <location>
            <begin position="179"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="558" mass="60282" checksum="03B9C2817A99220D" modified="2025-10-08" version="1">MSLLKERISSPLEAGTSILDSQGIPPYFTDALEYISRRLARKALHVTLIVVRKEYQVPSSCVTPTSSSTSSPTSFEFTMPGSPSRFASPVAGLRQLVRRGTNSSQASVSSVTSVDSGYGSTASSSYSPSMLPLQTPRRWPATPGSPPLCTPMTPHTPSSVTTATSTTSNASAGGPNHFGIRLLHATPLSAKDEKTLRATFYKAERKYRAGSGWLPPATTAAACGLSGDLIRRSLLQNEVLFSAEGLTLLGLDRLYTFKAALSAYARTTLPASSLTKPLLLPADRMMEDAVDELRRLVLANGGRPVTKADLHRRYDWIGVSASALSDVERMYRRAYGGCDRVGAFEVTAEDVGRVLLDLAPPPPPQHTVHFPSATQNVPIVKIGTPPSPKGPVLKLQTKFDDNKSTLAHRRLSNVKQPGIVRPQPRKQSRQGDRDFEDFEITLDGLEITNNDADEDDGDGDVTARPFTTGRPFWNSAAAEPSSSIDEMMMMKSQTHLSPIAAADNHRISRLSVSSASRHDGPTTPNGYDDISPITRGEWGFLFAGDGWSRPRQGAVETC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0D3</accession>
    <name>A0ABR1X0D3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003849</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671782.1">
        <property type="nucleotide sequence ID" value="XM_066808164.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041224"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF75">
        <property type="entry name" value="MYOSIN-16-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="10">
        <location>
            <begin position="175"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="416" mass="47705" checksum="BE0217782BCF6F59" modified="2025-10-08" version="1">MRKHERNVAEDDSTATEPEEPLLNWRNRCGNRQSARSVVGTSQYMAPEVIREGEYDARCDWWSLGIILYECIYGHTPFLSEEGGRQETKRNIVNHERTFAFPPRPVVSRRCMDLMAGLVREKESRLCSKRYHARDSQSFPIQPFRSSRRQSNRDWNGRSVYPHDAEDIKAHKWFRGIPWDKLHTVQPPFVPKISSLEDTHYFDEEEPISDWSESQPDTDSCSFPPNSGLGIEGGTAPIAEHDTVRLLDGLTTSIPTIPLPVNTNAPSLAAVSARCPRRVEAVQRQLAAYPKVVRNMMTRFVETPYDSARLKRIDREIETLTANPQEVEQLKKVVRTYGRKERKRPRDRLLRDRHTKGMVLEVRKQSAFLGYTWKRRGSNVLGDAQNNAVEGVVGVVGNMELDGSPMAAWPPRRTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0E0</accession>
    <name>A0ABR1X0E0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003822</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671755.1">
        <property type="nucleotide sequence ID" value="XM_066808137.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041197"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="80"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="294"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="640" mass="70522" checksum="27FDFC36F0112C2B" modified="2025-10-08" version="1">MGELPIAEDGSDEQAPISTRSPDKAKRGFRKWYAYIIAAVVLVVVIVLVAVLVPVLLHARVERTRDEQQKTPSDISKARVNLGYAQYQGSQLPNGVNQFLGMRFAAPPTGVLRWKAPKSLQCTRGTNPPIRLFGKICLGISQPLPNDFQGEDCLFANIWAPSNATTNSKLPVWLFIQGGGYTVNANANWNGSEVVQRSGGNVILVNFNYRVGLWGFLAGEQVRADGDLNAGLLDQRMMSKSGSSQACQPPLHDTAADTEFLFAVKWVKTHIEQVRHVNVLAPSVHKTPILTAWQFGGDPDHVIIHGGSAGAGSVALHLIANGGVDEQLFHGGIGESLFFPSQPYVSELEWQFSKVLSETGCQDATNPMQCLRGKNEKTLQAANVPSPFPGRTDMPLPLFYWTPCIDGQLLQDRPYKMFADGKFIHGTVFAPNTASPEEIQTFLQNNYRFLEDEEAKNITELYPLMEALPNHNAWFSSAQMAYGETTFICPAVHVLSAYHTQQEKADPERNGNNSASPGGVWGYRYNVADAVNAALGVGVPHLFESFAIFGPDNVPGAPESYYTYNAPMVPLVMDYWISFVRALDPNSFRSPGAPAWEQWGAGKRRLLLETGKTAMESTPKEQRARCDAWRELAPVMRQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0X7</accession>
    <name>A0ABR1X0X7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">isocitrate dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="5">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_003986</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671919.1">
        <property type="nucleotide sequence ID" value="XM_066808301.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041361"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF42">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="12">
        <location>
            <begin position="47"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8089025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="382" mass="41439" checksum="BF9BEEB4089652EB" modified="2025-10-08" version="1">MLSRNSARAAQRLVRAAAHQQPRAAARSYATIQSDIFKPTKFGSKYTVTLIPGDGIGTEVAESVKTIFKADNVPIDWEQIDVSGVDSGSPGSAEAAFRESVASLKRNKLGLKGILHTPISRSGHQSFNVAMRQELDIYASICLIKNIPGYETRHKDIDLCIIRENTEGEYSGLEHQSVPGVVESLKIITHAKSERIAKFAFSFALANGRKKVTCIHKANIMKLADGLFRNTCASVAKEYPTLEYNDMIVDNASMQCVSKPQQFDVLVMPNLYGGILSNIGAALVGGPGIVPGCNMGRDVAVFEPGCRHVGLDIKGKDQANPTALLLSGSMLLRHLGLDDHANRISKAVYDVIAEGKSRTRDMGGEATTHEFTRAILNKMETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1D1</accession>
    <name>A0ABR1X1D1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672028.1">
        <property type="nucleotide sequence ID" value="XM_066808410.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041470"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF7">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="66"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="351" mass="38867" checksum="5E4DBC1F78957928" modified="2025-10-08" version="1">MGSLQHLHLYSSARQPLLKEHTHVGGEPPSLPAKQVHTHPRKSNGDENASVYFIGTATTVIEWQGTRILTDPNFLHAGDHVHLGPGVSAERLTNPALDLHELPALDCILLSHYHEDHFDRKVEASLNRLFPIITTPHAKKCLTSLKDEPFGRVTELDFFESVMLHTGNEPTPGTDGKSAIRVTGMPGKHVPPGALAAANELLQAVPPVNGWLVELGYAHDTATGADPEAIKTGYRIYISGDTLFVDELKEIKQRLQDDKIDLMLIHLGGTTIPGPKMPLVMVTMDAEQGLKLMHLMDPEVTIPIHYDDYSVFLSPLSEFKDKVDEEGWHDRVVYLDRGEQYKFKVRAAEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1G9</accession>
    <name>A0ABR1X1G9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein mpe1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004197</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672130.1">
        <property type="nucleotide sequence ID" value="XM_066808512.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041572"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16620">
        <property type="entry name" value="vRING-HC-C4C4_RBBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014891">
        <property type="entry name" value="DWNN_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033489">
        <property type="entry name" value="RBBP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025829">
        <property type="entry name" value="Zn_knuckle_CX2CX3GHX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439:SF0">
        <property type="entry name" value="CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08783">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13696">
        <property type="entry name" value="zf-CCHC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01180">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51282">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DWNN" evidence="9">
        <location>
            <begin position="5"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="178"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="357"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="557"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="408"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="440"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="566"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="610" mass="67080" checksum="9B3CE34E81E9EF6B" modified="2025-10-08" version="1">MSSSVFYKFKSQKEPSRVEFDGTGISVWELKRDIIKQSGLGDGTDFDLFIYAEDYSEEYSDDTTIIPRSTTVVARRQPATKPGAGRAARYVTGKMPVNARNSSRREQHTKTVKPSTAGLAQMSTALTEEEKLAAIFQVQSDQWQAQQEEMAHQAPVYKPGAKKPANVPDHDPPNGYVCFRCGRKGHWIQVCPTNDDPEFDNKPRVKRTTGIPRSFLKTVDKSTLQQNEGEDGVKPLAGLMVNAEGDYVIAEPDKASWAQFQAKTKTSAAAQKAASEEDKELEEKGLLCAVDKKLFIDPMKTPCCEKTYCNDCITNALIESDFVCPACQTEGVLIDDLKTDEEASKKIQEYLKEKEIAKTKERSKSPTAAQSPKQASPVPDDGPATTDAATKKGEAAPASTDATDKTKSPTPSTSQAKSPPADTSNPSTASNPPANGVSKAEPEHVAPKKRPAEELLENPKIPKAPKAMQKAQQAREMQQNMMGGMMPNMMMNPMMGMNGMNGFPNMPMGMPMGMPMMPNMGMNMMNPMMGMNGFNQGGFPNMNGSFGNFGGNMGMGNNNNNMNGFQHQHPNRANFTQPSNDEDAYFRKPVNPGRHQNRQRRNRPSDYREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X302</accession>
    <name>A0ABR1X302_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">26S proteasome non-ATPase regulatory subunit 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004756</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672689.1">
        <property type="nucleotide sequence ID" value="XM_066809071.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042131"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040815">
        <property type="entry name" value="Nas2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035269">
        <property type="entry name" value="PSMD9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18265">
        <property type="entry name" value="Nas2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nas2 N-terminal" evidence="5">
        <location>
            <begin position="35"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="146"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="234" mass="25203" checksum="E7CB78AD2F5E7B3E" modified="2025-10-08" version="1">MGLPLRMDNIHAPTIPSGPSSRPLANGNAAHLSFAELSQKKENLEAELKALGGVLDSHGVTMETPLTTPDGFPRADIDVPQVRTTRARIILLRNDYKDLMNAIEKHLHEHFATLQDHDDAPSTTTSGPGMLGDSIPDTLDAPFAKVNSVVPGGPADSAGLKAGDEIRNFGYVNRTNHDGLKKVAECVQGNQGQNVLVKVSRSADATRRQELRLTLVPRLNWGGRGMLGCHILPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X453</accession>
    <name>A0ABR1X453_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_005144</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673077.1">
        <property type="nucleotide sequence ID" value="XM_066809459.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042519"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051915">
        <property type="entry name" value="Cellulose_Degrad_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620:SF16">
        <property type="entry name" value="LYSOSOMAL BETA GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620">
        <property type="entry name" value="PERIPLASMIC BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045319048" description="beta-glucosidase" evidence="10">
        <location>
            <begin position="31"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 3 N-terminal" evidence="11">
        <location>
            <begin position="60"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 3 C-terminal" evidence="12">
        <location>
            <begin position="506"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8090183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="602" mass="65857" checksum="958D661080BD9B3B" modified="2025-10-08" version="1">MAIHRKSLRAILGLITLSTLLTMGPLGVSAGNGQDATPPYRDASLSVDERVDDLLQRMTLEEKAGQMFHSQLNMGPDGTLDQGVPGTRNNTDFMLGTQMLTHFNLVGEILDARQTAEFVNRVQQHILDTTRLGIPLTLSTDPRHAFTENIGTGFRAGRFSQWPETLGLAALRDAKLVRRFAEVARAEYLAVGIRAALHPQVDLTTEPRWARISGTFGEDADLTAEMLSAYILGLQGETFGPGSIATVTKHFPGGGPMENGEDSHFAYGKNQTYPGKNLEYHLIPFKAAIAVGARQMMPYYSRPIGTEYDPVGFGFNKGIVTGLLREELGFDGVVVTDWGLITDANILGQDMPHLTELERAAMVIEAGCDQFGGETRPELIVQLVKEGIVAESRLDVSIRRLLREKFLLGLFDNPFVDADAADQIVGRQEYVDEGAAAQRRAYTLLTNHDDVLPLKDTANKKFYIEGFNATCLERRDLTAPFEPRSGGFESRYHAGSLEYSAQERERQAAIYTAVPTVVDMTMDRPAAVPEVAENAAALLANFGSGPDAFLDVVLGVAAPEGKLPFDMPRSMEAVEAQMEDVPFDTVDPVFKFGHGLRYKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4X2</accession>
    <name>A0ABR1X4X2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673365.1">
        <property type="nucleotide sequence ID" value="XM_066809747.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042807"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="34134" checksum="6FDD3D87F873BF11" modified="2025-10-08" version="1">MVGIENNAGGASAADGSDVNLSQLPSSLEVLDSFIDKLTPKPLLHAPAQGRRYTDGFENPPPASSIVWTAISDAETYGITTTVKGAAGPLVAGQMFSDRVRERIGDYEDFLHLAIRRQLHLERDSVDEVWSVTQQIPREGVDPVAFSAAKRAEAEAEVEAGAGINRDPSAVDPLDEFVDRLTPLDEDDDEEFEDLDDEDDERMDIEDHPPIIWTALPNDCVTTLVDGWDGYKLAQQIFRDRVEELIGGYGGPTVVCSKLAPAGCRNNYVNPHHFTMWIVPAEDSERGWIQLGHDPRIYTDGEPEYLQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7V3</accession>
    <name>A0ABR1X7V3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673526.1">
        <property type="nucleotide sequence ID" value="XM_066806230.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039290"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="62" mass="7231" checksum="673F015D86937D7E" modified="2025-10-08" version="1">MNVCQKLYCADSTSVVMRTEANLEALRRDCSYWDYDIHGVAVWGRAYDDQEFYVDVQWALGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X889</accession>
    <name>A0ABR1X889_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosine deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673611.1">
        <property type="nucleotide sequence ID" value="XM_066806315.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039375"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114:SF7">
        <property type="entry name" value="ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="4">
        <location>
            <begin position="14"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8091639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="189" mass="21005" checksum="759074633ED035CF" modified="2025-10-08" version="1">MNGLQISPFITSLPKVELHVHIEGTLTPSLRWKLAQRNRIPLPYATYADLLESYNVLYNHRKELHGDTGAPTFLETYFAGTQVLCEEDDFYELGMAYLEKAADMNVRYAEPFFDLQAYLPHGIPAATVLNGYMRAQREGAQKFGVRSNWILCFIRDRPVEEGIAAYEGGAALGGRDNGGSWAVSRGGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8W3</accession>
    <name>A0ABR1X8W3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673831.1">
        <property type="nucleotide sequence ID" value="XM_066806535.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039595"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="202" mass="22577" checksum="F2F63AC95D6901C9" modified="2025-10-08" version="1">MSGPPETLTLTNWATVKQWNPDDPELQEVLDDAKAIEKLSEGQPYLTTEIMTAYVIARDPFPKKKSSYVGSGAWLPGLSRASTAAGPGASPSSAPPPYDHDLALIKLEIWLKNENRRWPAKSTTKPDRRAEDELAKRFINDVLEDREALADDTVGQVSAYFGRWASARWKPKPMPPNIPVIVYHSRRLQSCILLDAETIEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X906</accession>
    <name>A0ABR1X906_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673908.1">
        <property type="nucleotide sequence ID" value="XM_066806612.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039672"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="132" mass="13713" checksum="2A376A2D059100DA" modified="2025-10-08" version="1">MSLNTTPVQSPASDASPRSQPTPRRGDYFDDAGRRAAQTSSPNNAQPSSSSRAEVKDDTSASSVSTPGNETVPSPGAETAPSPGSSGPGPLSRKPSVSSVSFRQPNNPKLPQGQKKPHGSSRIRDASPPHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9D3</accession>
    <name>A0ABR1X9D3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">EIF-2-alpha kinase activator GCN1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002390</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GCN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674001.1">
        <property type="nucleotide sequence ID" value="XM_066806705.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039765"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022716">
        <property type="entry name" value="Gcn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056810">
        <property type="entry name" value="GNC1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057546">
        <property type="entry name" value="HEAT_GCN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056809">
        <property type="entry name" value="HEAT_GCN1_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019399">
        <property type="entry name" value="Parkin_co-regulated_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF7">
        <property type="entry name" value="STALLED RIBOSOME SENSOR GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12074">
        <property type="entry name" value="Gcn1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24993">
        <property type="entry name" value="GNC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23271">
        <property type="entry name" value="HEAT_GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25801">
        <property type="entry name" value="HEAT_GCN1_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24916">
        <property type="entry name" value="HEAT_GCN1_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10274">
        <property type="entry name" value="ParcG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1312"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1467"/>
            <end position="1505"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1610"/>
            <end position="1863"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1927"/>
            <end position="1965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2581"/>
            <end position="2601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8092029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2624" mass="284715" checksum="ECFFC0A2EC2D4DE4" modified="2025-10-08" version="1">MTEATTNGASPARVDLVAAKADLSSASTKTRIAQLKSIEEKFKQNAVDVSATPRVLKLLFDTHPAYNDRPSRRAVQSCLVSIVANASEPKAIAPFINALRLESQKAGIAPNNAFVLVEWCGSLLSTIAATPMLGQFGLDIVHANAAALERCFQPPTRSSVADSAITVTRRGLRAAFWQKEFRGSFIEDVVKALTTKAGQSTARNAVMLGVVAGVSSRHDKAKPVLASRKADYFGFYTREIAGSKTQLPDHIASGLRDFFLDFVTFEDLTKEVVPSIEKGLLRAPEVVMGLVPRLVTSLPQDMDLSTVLGGHLMKPLLANVKSSNPVIRQAVKTTFETTVSKCQDFKILEQVADEIVGPLKSGKLASADQRVLHSEMLQSLPLSASIASKVTAALPLVVGKEGNELALAAELSAFTCCVSYEIQHNVELAKPVLDAYIKGLADKKIPSRRLWILKAGEVLSYFKNTQEAIPSNAVKFAESIASPLAESWAEVNKNPLAAVQSTLISGAYVVTVLAYQIFPQVESQSIKASIKKAAVSKESLVLEPKPSFLLNHRIYNRLSAEDDLRWFLAALSAVVVDLAEAPGSVRSAWSQALIFLASSPTVPPQIRKETCETITKLYAKQPTLVSEAVVAGLWQWIESTELSDKESVAASAKFDKTNLHLPLRSICLTEEDFKKEGTERNLEAIEKQMCSLVALARPNLIPRSNWIESCLKVGLDPGSLVLRHEASLLQEITDKTSFEQKSSAIKTAACNAVADLAFVAPEIMTSKIIELIRGDLDPDQLKDVGPVEAAIFRTPEGTACIDVLAKKSQALPNKNTKDYDTLKWEEDLRAQLAAKKGTQKKLTADEQAKVNAQLKKESEIRKSVQLLAARLLRGIGIIQGLINGPPTEASLWMGPAVNALLKAMEAGACLITGDAAPSVYLACADKVTDRLGSIRPFIGVATLRALGVTGLPENLEEEGLEELITRVLYRLRFAGEQRPFDVISVVYMLSLIFLVLQHGGFGAAAEERDAQLVLAIEFVSFHTDVCAEEAVPRSDLISTMITSMQRYNQHYKIVKDCFSDMIRCVAPNMISQEISVLAKGAIVPESSVRETVLQSISAEVDMSELDFSDEIWIACHDDDETNIEIAREIWDEGGFKVSKDVPFKMIPYLESKDGQLRRASARALADACRAHLPTVNEVLQNLQARYIEFAKPRVAGFDSYGMPRKTDLADPWEARHGVAAALKSLAPCLQKDQVDGYFSFLMEKGPLGDKDPNVRGEMLEAAITAIDQHGRALVDKLMKMFERTLEAPDTGSEAGDRVNEAVIVMYGALARHLKPGDSKIPVVIERLLATLGTPSEAVQYAVAECLPLCLKSATENKKEPQQREGAFLAFELAPLILGRLFEPYAIQIVPQLLTGFGDSSADVRDACLAAAKACFAKLSSFGVKQILPTLLNGLDDDQWRSKKGACELLGAMAYLDPQQLAQSLPDIIPPLTGVLNDTHKEVRSAANKSLKRFGDVITNPEIKSLADILLKALSDPTKYTDTALDSLIKVQFVHYLDAPSLALVTRVLQRGLADRSNTKRKASQVIGSLAHLTERKDLIAHLPVLVSGLKLASVDPVPTTRATASRALGSLVEKLGEDALPDLIPGLMQTLKSDTGAGDRLGSAQALSEVLAGLGTTRLEETLPTILQNVESSKAAIREGFMSLFIFLPVCFGNSFANYLSKIIPPILAGLADDVESIRETALRAGRLLVKNFAARAVDLLLPELERGLADDSYRIRLSSVELVGDLLFNLTGITGKEDAEDELDQAKEAGASLREVLGEEKRNKILAALYICRCDTAGAVRSAAISVWKALVATPKTLKELTPTLTQIIIRRLGSSNMEHKVIASNALGELIRKAGDGVLSSLLPTLEEGLQTSTDTDAKQGICLALKELIASASEEALEDHEKTLISVVRTALTDSDEDVREAAAEAFDSLQQIIGKRAVDQTLPFLLNLLRSDDEADNALQALLTLLTETTRSNIILPNLIPTLITPPISAFNARALASLAKVAGAAMNRRLPNIINSLMDNIVNNEDEDMRKDVESSIDTVILSMDEYDGLNTVINVLLQLVKHEDHRKRANAAYRMANFFDQATVDYSRYNQDIVRALLISFDDRDKDVIKAAWTALSTFTKKLKKEEMESLVPSTRQTLLQVGVAGHNLPGFELPKGINAILPIFLQGLMNGTADQRTAAALAISDIVDRTSEASLKPFVTQITGPLIRVVSERSTDVKAAILLTLNNLLEKMPTALKPFLPQLQRTFARSLADTTSEVLRSRAAKALGTLIKFTPRVDPLVAELVTGSKTTDAGVKTAMLKALYEVVSKAGANMGESSRTAVLGLIDMDTDNTDSTMTVTNAKLLSALLKNVPADVANSLLKSRVATTHFTNSSVLAINAVFVESPQILLDSPLAEDVPEILSQGMSNKNLFVADNCILATGKYLMSHTPSFEQAKPIFSTLATIIAPGNPTDSRRLALVIIRTISRTNVDLVRPHLPLLAGPVFASVRDPVIPVKLAAEAAFIELFSVAEEEGRVFEKFVQSPAGQELQPNTRRSMNDYFKRVGLRLGAQTRERRQAEGGVGGQGALGLSNDEVEDEREIWSVGQVELGGGVFSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA24</accession>
    <name>A0ABR1XA24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000192</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Vacuole membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ATG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674280.1">
        <property type="nucleotide sequence ID" value="XM_066804507.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037567"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8093507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="119" mass="13807" checksum="ACFEE9307255E147" modified="2025-10-08" version="1">MRSKFKDEHPFEKRKAEAERIRQKYADRIPVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYITYSGENTFGESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAY8</accession>
    <name>A0ABR1XAY8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674536.1">
        <property type="nucleotide sequence ID" value="XM_066804763.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037823"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="653"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="945"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="695"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="955"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="969"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1098" mass="119842" checksum="885613C4D81AD6FD" modified="2025-10-08" version="1">MPPTNPETTITSHWAISSTLPSSTIQLLFGSRQWDRRSVAGMAPRRTLIKKLYKRLRTNQVEDDCLTAFQFVEIKFYLKHHKRCHHITIRNDLPLDYLACSLPDNLPQFVLSQLEAQRLIADDHRLSVQVWSVIQTISDCFSRDPSHTRSYPTLFYWRSPNKQRSYYLFAYLTRAMTTRKYKASELLDLRDIRPCQDILDRVQKNPDVVDIVTGLRRNSILSDGSNVAMPRRPKKIKEEASSTDSEDQVLFQGRKAPPRPTVTNGDATSDPKPPCRNEPDRTEPLSAPTGLAAQQSEGFQRFFKAVVSPTHVRVTAGGRIVPNTRSTASPTAKWDKELPNSESDTNDIGKSSQSDQQMPTTDPATCQTAPPVMAPPMASPMYPGFPAMYPPMAGPMPFFPHPMAGGMGFPYPMPYPPMQMPAMASGSQNAMPQAQAPQQAENPTTVPKPENRQDSRKPKPAPLKLSPPEQFDQNRPFYYNGHFIYPPMASGHMQSPLPPMTPSPCLPPGFAGHPGIPGHPALARVGSFAQPSSGSSLPSPHVMPAQTSMPLTASAAMPQPVAPQSQGASKSSASNHFPSSAKPPPSSIKPSEITKVQLGSLRSQLKYYEDQLQYNKHQIDEEKTKEQIGAIRQLIVQFEHNCGMQMHFETAQYSGPDAKNTNEAPNPETGAAPCQTPSRESSMQESDDVSVPQVPENSATSSRRGNPTLAHTQSMDQIRPRTVKERRQAAGINSSKGNDTSAALDALVARLNMSGEDSKASSSFITPAVTSSFEPSRTSSLSMGKLAGIESSTNPMLHNNMQLESGSSLLHPQQSPWQDFGSYVTGARAPTHPGVGHHPVGTNTYATPYLVGVLPQGINPQAARGTDYVYARELTEEEKRARHVYWGQVSIKGSGLPKGMLPTGRPEVDFGFAGPKKTTGDPFHAGGDKGTGKVSHAVPIINPETRDPLECVQTPKASNGTKSSAALASDEKAPSPSRRIFDRSSNKSSNDLWHSMLKKGTASGVAIPRTVSSTTATGYVPSLSSHGTTSLGPALVNANGHATRSHLGKAEQEPIVMPAEKVGENRPPQQQTLKQQDDIADLHQRMLRDAERRGINWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBC7</accession>
    <name>A0ABR1XBC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674702.1">
        <property type="nucleotide sequence ID" value="XM_066804929.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037989"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="119"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="24336" checksum="34C93F3179BB70A8" modified="2025-10-08" version="1">MMDPVSAVGVVAAAAQCLGIALKTIRFCYQIRDSAESATDRNKELERAAEERHQSNIQRKLEEEFLSSLLFNEMNDRLLSVKGAAPNTLEWLFYDPDSDGGLSVKASSQKIPKRYHRWANFHQWLRTDSSLYWICGKIGSGKSTLMVHIIQDRRTRKGLDIWKGQARLHVFQFFFWRPGSELQKSILGLLRSLLYHSGSPQCLLNLCRSSMTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBU8</accession>
    <name>A0ABR1XBU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2 type master regulator of conidiophore development brlA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000754</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674842.1">
        <property type="nucleotide sequence ID" value="XM_066805069.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038129"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="138"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="376" mass="42092" checksum="C1E67331A17FCC26" modified="2025-10-08" version="1">MELMELVENEPTARPFQCDWQSCNKSSSLARHRRIHTGKRPYKCAHEGCLKSFCRKTTMVKHQRRSHQRGIHSSEIDDCTSESDGGESPTTPRLSAMQWPQSVSLAGHPGIHGHSLHRAASFADFGQHLGYGMQQFNHRHSVSSGPHEYHGQSIQEQQQQQQQQQQQQAHQHPHQHQHQHQQHPGAQMLHRTTSMPQHSYYVTEHSNPGVATLNTNPMSTYQVPRQQVERLPLEIPYTAAGLTGSIQSSPSTFSPASGRSPSAHQDGFYTHQPAQTATYALHSTSPVVEHPPQQPMVQYAQQMPQPLPASQAVPSQAPSTQQEEHWYNGVAYQAPVEVATIGQLPTYGSGVYDPWAIKPDFDDPSMQMPSARLETM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBZ0</accession>
    <name>A0ABR1XBZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diphthamide biosynthesis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000864</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 [3Fe-4S](0)-[protein] + 2 Fe(2+)-[Dph3] + NADH = 2 [4Fe-4S](1+)-[protein] + 2 [Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71239"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:17998"/>
            <dbReference type="Rhea" id="RHEA-COMP:18001"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[3Fe-4S](1+)-[protein] + Fe(2+)-[Dph3] = [3Fe-4S](0)-[protein] + Fe(3+)-[Dph3]</text>
            <dbReference type="Rhea" id="RHEA:71235"/>
            <dbReference type="Rhea" id="RHEA-COMP:17996"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:33751"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DPH3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674952.1">
        <property type="nucleotide sequence ID" value="XM_066805179.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038239"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF31">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DPH-type MB" evidence="9">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8094179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="91" mass="10248" checksum="E6411BEB89B056F2" modified="2025-10-08" version="1">MSADEEIAVYDEVEIEDMEFDEAQQIYHYPCPCGDRFQIALEDLQDESNDIAVCGSCSLMIRVIYDKDDLPKPDPDPQAPEQPVEQVPVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC50</accession>
    <name>A0ABR1XC50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674946.1">
        <property type="nucleotide sequence ID" value="XM_066805173.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038233"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47941">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="189"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="55400" checksum="3CDB3DF845E74D2C" modified="2025-10-08" version="1">MSKEELLGFLDFYDDISVEERLEFLKDPYMRKYAPPEDTSLNVSDRLHELVAPAPEEVERGSQEDMEVVAKLRAAVYSRLLRPHSVDLETIYDLYLLLPGHRIPYMSSRLRHSLFAALGITERKSPKAMLRYFAVVADTKASGFALSRTEWNTAMSFASRYVGTSTDVEAEAALHLWREMEQDVGVKGNEATFNILFDVASKAGKFALAEMIYQEMNTRGFHFNRFHHVSLIHFFGLKMDAGGVRAAYREMVNSSEIIDTTVLNCALIGLLRSGEEASAERLYNKMKATDRRSKIIPERNYTSQKKMTKVMLMFARVARKHPDMQRGFQSTSLTTPDLHTYRILVNHFGVRLGDMSRVAQFLDEMKFFRVPLHGSVFLALFKSFAQHGSDGSDWSVQRLDSVWNAFLDAYDAGTDGLYVSTWMAMWILRSFAHCTRSQDRVLGVYEELSLRWELDSQNRSFMLDFCTSCSARAACIYVPPSPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC60</accession>
    <name>A0ABR1XC60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alpha-1,3/1,6-mannosyltransferase ALG2</fullName>
            <ecNumber evidence="12">2.4.1.132</ecNumber>
            <ecNumber evidence="12">2.4.1.257</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_000899</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>a beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19511"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58472"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="EC" id="2.4.1.132"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10 12">
            <dbReference type="Rhea" id="RHEA:29516"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29519"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="EC" id="2.4.1.257"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11 12">
            <dbReference type="Rhea" id="RHEA:29520"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.132" evidence="12"/>
    <dbReference type="EC" id="2.4.1.257" evidence="12"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674987.1">
        <property type="nucleotide sequence ID" value="XM_066805214.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038274"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03805">
        <property type="entry name" value="GT4_ALG2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027054">
        <property type="entry name" value="ALG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918">
        <property type="entry name" value="ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918:SF1">
        <property type="entry name" value="ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="456"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="14">
        <location>
            <begin position="25"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="13">
        <location>
            <begin position="238"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8094214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="492" mass="53774" checksum="622D990974F61B63" modified="2025-10-08" version="1">MAGEKKKTTAGKAKTIVFLHPDLGIGGAERLVVDAAVGLQNRGHKVVIFTSHCDPTHCFDEARDGTLDVRVRGNTIVPSSILSRFSILCAILRQLHLILQIASFSTELKSLAPDAFFIDQLSAGLPLLQYLYPSGRILFYCHFPDLLLAQGRQRWWKRAYRVPFDWVEQWSMSFADAIAVNSNFTKGVVRRTWPALAAQRGGSNGGDDFETIYPCVDTKPKKSEENDEIETGKPLWGGMRFLLSINRFERKKDVALAIKAYAGLSPSARKGVRLVVAGGYDPRVPENVGYHKELVELADSLGLTNTTAKTMVTALEVPPEINVLFLLSVPNLLKEMLLKSARLLVYTPANEHFGIVPLEAMLVGVPVLAADTGGPVETVLEGETGWLRSPAKVGEWTEVMDSVLTKLSPSEMIKMSQTGVSRVRNNFGDVQMAARIDAIMDKILATTTKPGSWGPLFLFGLSALGLVGAGLAVLANLVNSRGSKPVMHEHQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCS8</accession>
    <name>A0ABR1XCS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF1445 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-glutamate cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675228.1">
        <property type="nucleotide sequence ID" value="XM_066805455.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038515"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1640.10">
        <property type="entry name" value="PSTPO5379-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2040.10">
        <property type="entry name" value="PSTPO5379-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009906">
        <property type="entry name" value="D-Glu_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038021">
        <property type="entry name" value="Putative_hydro-lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32022">
        <property type="entry name" value="D-GLUTAMATE CYCLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32022:SF10">
        <property type="entry name" value="D-GLUTAMATE CYCLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07286">
        <property type="entry name" value="D-Glu_cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160920">
        <property type="entry name" value="PSTPO5379-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="34905" checksum="855B33DCAD9681DA" modified="2025-10-08" version="1">MAAAVLVATSSSNTSLSKEQEPGSPIAPILSSGLKSPQSLPGPRPGRRQRPVWPRYVQANLIVLPSRYAADFRLLCARNPVPCPLIAESAAPGKYDSFKSYVAGGADVLSEGGCVDLRHDIPRYMVYRDAELVRAEALDIESEWDDGDHVAFLIGCSYSFESALSLAGLVPRHTVLGRNVPMYRTRLPLCPAGVFTGSTYVVSMRPYKSREVEKVRRITRGYSATHGEPIAWGWEAVHSLGILDIDAPEWGEAPVTADGRPLGELQAWQGGSAEDEVPVFWACGVTPQEAVMRANIKGTVMAHAPGHMLLLDCKDHDIVNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD27</accession>
    <name>A0ABR1XD27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001207</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675295.1">
        <property type="nucleotide sequence ID" value="XM_066805522.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038582"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="81"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="371" mass="41434" checksum="CA80B3D36E9CACC9" modified="2025-10-08" version="1">MASPVSSNLHVGNSISRPQGPEGPRPLSLPTRLDQHQSVIEIPLPLLPLPPQQPCGLAQDLILPGCPLTTTPRLLYGTAWKNQDTANLVYLAIKSGFRGIETAALPLYYQEPLVGNGVRRAVDEGIVTREELYIQSKFAPPDNETQYCCMPYSQDMSLKEQVRASVESSLSNLAVSCPTSPQPAYLDCVLLNTPLTTLEETVAVWQALEEFVPHRIRHLGIANVNQTIVEHLLRPPVATRSLAEWKIRVRPSVVQNHFCPRLGDEDVYFVRLRRLCRQEGVVFQAYYTLTGNKKLVRKSTIVSDLVARVPGVSRETAFYALVLGLRGISILDGTKSEEHMRADVEGIKQIERWADGEGRPFWENFCRSSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDH2</accession>
    <name>A0ABR1XDH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675494.1">
        <property type="nucleotide sequence ID" value="XM_066805721.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038781"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046460515" evidence="1">
        <location>
            <begin position="16"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="88" mass="9249" checksum="5E9DA66307A667C4" modified="2025-10-08" version="1">MKLVILSTIFGTLLATAVDIQTASIGPNGPPDGVPACSVFQDTKCCITQLVCQCYNGKFYYANSDNKCAPTVGGNMADTESQLPGYCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDN9</accession>
    <name>A0ABR1XDN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675570.1">
        <property type="nucleotide sequence ID" value="XM_066805797.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038857"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="435" mass="49904" checksum="C0BE82914C0A614E" modified="2025-10-08" version="1">MAGTSGSHRLHFIMPPGLERFPLFFSLPYDIRYKIWKEVVYVPGIHFLKFEAPRTPPRRPNSDEDSDREDDDAASSQSSRRQPRERQRDATPLYSANLKPIYPLPAADLSYYITANKNLTKLSLSCGEAAELLRMSTNKPGNLVLDSARLISLAGSDDVICIDYPDLNWSRNLGSWASKLNQTQLDSVRRLAVKYHPEWDEDRRRCRLCGRVHGSVKPHVHHHLYEFAALFKNLERFYFIDYHTIRRSVSKDLSRLSLDNEPRWPGPSSGHGIAGGQKFLSGGRTYYELDPQDCQLNSKVFAKLDWVRSEYITYCKADPERHSNPAKVKFWVLGCEWDYEQLEYRQNAAHLAKGRSPRRKSHTRGNAQQADIANMMEKMELNGDKGGHRDFEQPAGLPVQFGGNNDSTYQFEFSLKPKARMTTHPGRMESPGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDP3</accession>
    <name>A0ABR1XDP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Neutral protease 2</fullName>
            <ecNumber evidence="13">3.4.24.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Deuterolysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_001495</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Preferential cleavage of bonds with hydrophobic residues in P1'. Also 3-Asn-|-Gln-4 and 8-Gly-|-Ser-9 bonds in insulin B chain.</text>
            <dbReference type="EC" id="3.4.24.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the peptidase M35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.39" evidence="13"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675583.1">
        <property type="nucleotide sequence ID" value="XM_066805810.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038870"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11008">
        <property type="entry name" value="M35_deuterolysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050414">
        <property type="entry name" value="Fungal_M35_metalloproteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029463">
        <property type="entry name" value="Lys_MEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001384">
        <property type="entry name" value="Peptidase_M35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016:SF2">
        <property type="entry name" value="NEUTRAL PROTEASE 2 HOMOLOG SNOG_02177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02102">
        <property type="entry name" value="Peptidase_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00768">
        <property type="entry name" value="DEUTEROLYSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01351">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0165">Cleavage on pair of basic residues</keyword>
    <keyword evidence="9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13 15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 13" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 13" id="KW-0732">Signal</keyword>
    <keyword evidence="10 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="12" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045005275" description="Neutral protease 2" evidence="13">
        <location>
            <begin position="17"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Lysine-specific metallo-endopeptidase" evidence="14">
        <location>
            <begin position="207"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8094810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="360" mass="37690" checksum="3C74763DE5D224D5" modified="2025-10-08" version="1">MKFFATVTLLASAASAAVLDVTKRDVPLAVTLEKTGNTQVKATVVNNGKEAVKVFKTGTFLDDAAVEKVDVFQGYLLTYNSPNKAEKVAFDGLRLRVATSGLPEDAFRVIAPGASVEATFDIAHLHDLSQGGAYDVVSTSGFLTAALDSTTLDGVVPYTSNTLKAVEVDGAQAAEARASFIGRRTSLQSDCTGSKSTAIRSALSNCASAARNAASTARSSSSKMTEYFKSSSSSTVSTVANVFTKVASECGSTSGGSSRLYCSDVYGACSSGVLAYTLPSSSYMAYCNLFFSALSGVSRTCHDQDQASTVLHEATHLTQIKGTSDYNGYGYSYVRSLSASQNLNHADTYALFAQSIYAGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDS7</accession>
    <name>A0ABR1XDS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675600.1">
        <property type="nucleotide sequence ID" value="XM_066805827.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038887"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="272" mass="29341" checksum="AF520DF6E82B3020" modified="2025-10-08" version="1">MGVFPVQPNFAGHPHGHHQHHHHHMNNQQQHVAPPGYSSGVQNVYIWPCGVSHISFPIVDYTRSAWTALGYPGPHFYMATLPNTAQVSDLVARLAPADSGKVLMARSHKGGGCFDAAEASSVASLQKAALQLEVWAKDDVDGDGDDHKSERVSSTSTNGTTHHHKKGKGKQKSSRVPSPSVVDADDEDDQADEAGETQADDSRSSTSSGYDPDETLFDHIPLPSPAWPHFQYMGYGGGPNNYNPTINNPKLRHGPQARKASSSGATDERKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDX4</accession>
    <name>A0ABR1XDX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675633.1">
        <property type="nucleotide sequence ID" value="XM_066805860.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038920"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="LIPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981:SF1">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046144826" evidence="2">
        <location>
            <begin position="25"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="492" mass="55684" checksum="54F6AC5030B9E64B" modified="2025-10-08" version="1">MAIISCSWVNVLTVYSLFSTAVSSTNQVETIKHLLGWDKFEWTALGDSYSSGVGADTYTPNSYRCLRYDHAYPVLMNSDGRLPKGDHKFNNVVCSGANSMEIEDYQLYDEDTFAEPNFQYGNRPKFGNPSMATLSIGDAHLGRPPPRSCEEQKEITWRLLLSPDLSDNIARTIKKVVDKGRQGPIGNKFRLYVTGFPQFFNDNTTECDSVTFARTANPSPDGMDHVKLTREVRKDYNNMSVKLNQEIEKAVKRHESDGVRWVPIDPVMEGHRYCEPGVKEPDQHNDKLWLYHYPYDEPGDTEVMKHLEKGASRVMLGKRQTYADYENQVFDALELRGGLIQKTAFDFFWREVGKRMKVFHPRIPLHERIRDLVLDAYVGDLKGNAGSGGGSTEPSKPNENECHSISGDTWVMSRDQAVDNVKAFCRHTQSKARYNKGSANELELSVSRKGGSDKRPKGAPNCEARFTRAVIDGCDGDDSKYLFAQDFDYGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE77</accession>
    <name>A0ABR1XE77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675753.1">
        <property type="nucleotide sequence ID" value="XM_066805980.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039040"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="399" mass="44787" checksum="6B43128B4AFCAF13" modified="2025-10-08" version="1">MTNARVPQASKHRQESEKRINVMLLAIQDRLLGLKLYSHIYTGRHGLDQQLQSKIFIAYHIFVSFCTAVVEYYELGGFVRWLLSLTHATGLEDKAASVQGAIGAVRQVGEELLHKSAAEIKKKLQSVEQMNKSQLAEISGRFLLPFPDSLVQFELTTVQNSSSEFKIYNRVRTVKTWKGYVKPWDWITYSFGSNVVDRLAEVEAQPAFHAWLDSPRSCVLVLAGRNQVHEAAHCWLSLIAIELVKRLSKSSTPELFTFFMVGERGMDDTFDHTLSTIAYRLLSRHRGVLRNKVAYDRLWTALQDYRNMKADESARRHEVHRALRNVVLAVLDLFEPGQTVWIILDRLDQCQCATGEQELPPKGCAQELGKLGGGQGAGSEAKSLGGGQFLGLERGGAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEL0</accession>
    <name>A0ABR1XEL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_001762</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="3 8"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675850.1">
        <property type="nucleotide sequence ID" value="XM_066806077.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039137"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047403735" description="Mannan endo-1,6-alpha-mannosidase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="427"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8095077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="487" mass="50932" checksum="91ECCB710FD45A1B" modified="2025-10-08" version="1">MVRPLNSVLGRVLLSVPAVGAALDLDINNEDSVRKAAALVAEDLMSYYEGDKPNEIPGILPGPPPDGDYYWWSGALLWNTLIDYGNVTGDAKYVDTVVKGLGWQLGQHKDFMPANWTAQMANGDQALWAGAALTAAMSGLPGPSSSSSGVSDWLAPARTVGIDEFPLRLINNGTCQGALRWQIFQFNNGYDYVDSKVEHPRLVGRVNADSCLKTATSNAAYFALAAGLAYETKNDTLAKQAASSYDLMTKIGLIDDDFSVFDGARVSADCKGVNMLQFSLNPGLILTGAAYMLQQTNNDENWKKRLDGLLDHALKTFFPDGVAFEVACESSGKYTCNTDMKQYKGALHRGLGRTVQLAPHTKDTIMPVLKTSAAAAAKTCTGGENGRMCSSVWAAQGDSGSEEARKDGAAAQMDVLNALNSVLMASTSSGSSKPATGGSASGDGGKGQGSSDAAGGNKGTPGNMGASAAVSTSILLGGLFSSALALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQH0</accession>
    <name>A0ABR1UQH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660571.1">
        <property type="nucleotide sequence ID" value="XM_066819686.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052746"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.16.10">
        <property type="entry name" value="Hedgehog/Intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="826" mass="89802" checksum="B6B2B36E73254BEC" modified="2025-10-08" version="1">MADSPSFTAFSGFDEIADQLPDVGDFTSTPPPPSSPGPESPSSYPRYSGVPQVTTASIDWLGLAKLFGFGKKEEPAPSPAEPVVEVRTVQIKDIFKMSQTDKGYSFNSHPAILMAVAYMQKSLDYSWREKPVRETIFPNIKSALAPASLTVDGLEKSKFDDGAVGLLVKAFYNACQDRQGSIEIDKANSAVQSLNDHISTQATPLLVQFYRAFFFLHPSDELVHKYKTLLLSSAYRNMKQHQASQGFWPHASLEMFCHFAKLAACGASDEQIREVYVGLTTTEPKLDPGSFGEIRPESWRAYRAWLSSGYLDWGDLNAEHLDASYTEVTSSGGMYPYGPVMSTYTVSLADDFIRSKSYWKAPQSSSCFAGDTRVVMADGTELKRISDIKTGDLVLTGTTSRRVAFVSSPRRNARTLYSLAGYPGVKFTETHPILSPPGSADDAMDDDQVGNVVSFVNKDLASSLNPTWQSLRTENISQDLLQACNECDDEGEILYDLVFEPNLGGDSHQSVPLASYVLEATNGRRLIVASEAPVIEWFPLETIFISCAVERMTSQVEDIGATAELVGSNKICTRSLLTEAAAKITTTNAADPIVNSKDIDESLIASRLLHACAESQPTAELAEKVVAYAGRTLSHEIKNGWARPVAASDVSSGQSVLFLNVVRLLDNIDGARAWTISADYHLKVWAENEIIFDGSVSGSIQGNCTLDLHYPILLDRGATEEGLLTCRSIAMELSDPSSSSAWYGAGPIRDGIQSVISLGDTPKVSGMATQHGVAEVELRTVEVGMDSASLASLHHAWHPKDMVTYAQELGIAFGELVLGVFEGSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT00</accession>
    <name>A0ABR1UT00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660663.1">
        <property type="nucleotide sequence ID" value="XM_066818475.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051535"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="190" mass="20951" checksum="A4D4AE359EE96517" modified="2025-10-08" version="1">MNTIAMKVFTMNARPKSIKEARFTSIAEIVPDGRDIKSPNLVSVVFPTLETFTSLLGIQPTDGRVTTQPIIIQYAPTPPDSPFIHKLTYTRAGVVLSSYPCTITANQYHYPSPSQQPAFTHIVDPDPAEINQQTPMSPEVIVSIVFGVIASLLAIAGVVATLYRHRKQRDADRATHSEGLLLDCLREQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTH8</accession>
    <name>A0ABR1UTH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660819.1">
        <property type="nucleotide sequence ID" value="XM_066818631.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051691"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="16063" checksum="7E44382B1A232FF2" modified="2025-10-08" version="1">MSHASTRLHPLVDQIPGYIKATNGVLNSGDQLIRWLYYTYDFYVSDEDEEEDEEEEAMEGEEMEEEMEEDSEDEGEESDDQESDVGDDQDDSDQDDSEQEQEPVEANVGEVEFHLEEPSEEYARRVNAYNEWVRYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUG3</accession>
    <name>A0ABR1UUG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661131.1">
        <property type="nucleotide sequence ID" value="XM_066818943.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052003"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053008">
        <property type="entry name" value="Phomopsin_biosynth_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="222" mass="24733" checksum="48C96FAEF09BD874" modified="2025-10-08" version="1">MEYQSLNTDPEAAERTDFTPEKPGAKPKLWQKAKTQDWGLSKTLIATAVVLLAAWGAIDTSIRALQLAQSVLRKEYRSPCWCGTSDAEAVAMGCTWDHIAVDWLPPHCVDHKLMTEFDAAGSGPNGAWPYYISDARNVALITEAQRSPVNLTDIDELAREGREYWTTVEWHISHCLFTWRKQVRSAASGGAVSVEPWNDKEAHASHCSMYIWDVLRTGEAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUI1</accession>
    <name>A0ABR1UUI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660961.1">
        <property type="nucleotide sequence ID" value="XM_066818773.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051833"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39602">
        <property type="entry name" value="ACW-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39602:SF2">
        <property type="entry name" value="ACW-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045712607" evidence="1">
        <location>
            <begin position="22"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="30347" checksum="69EBD270037FDA39" modified="2025-10-08" version="1">MRFSSNAVSASLCAWLGVALAEKTIGTWTLSDVHRTRSPDNTTCNWNFTITASEIRGARPPAQCAFTVRGTKALGCDKRDLGDVTCTDGATQYDVGGGWSSQGFVVISVVNPTENAQAYFGYSDAQLNGGGDLPAQDKDAILIGSDQTSTAASSSPSSKIVEREALPIEKAQAWTVVNLKRVVDQDRRQVIVNFTLEAENAQGVFCVLQIAGPQNTNLATWPWYDRRCKGSSGWTVSMGYVPDGDAGIITVVSPSRHREAFFGVRGINEAETLGSIGPNAVADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUS8</accession>
    <name>A0ABR1UUS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014778</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661280.1">
        <property type="nucleotide sequence ID" value="XM_066819092.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052152"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="470"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="7"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="673" mass="76248" checksum="FE50B3124BE6FF32" modified="2025-10-08" version="1">MFFKWLRQQIAEQQQQRQQQRHQQQQQQQQQRESSSPAQAAEDSLPPPVPPPSSAIDERPDGDDVDSRVEDRQHLTSLERFLSSRVPAQCAGCSRLIELSADNVTRSVQRWWKERTRRSGTKKVELACGLCCGKQSCHAVTCPCGSTVSTGWLNRHELKARVSGTRFVFNHCCYQGRLVAVWMLATATSQSQPSSTPSISSGPKETNNGTNAEGVGYARSEPILQRLINRKPPRINTPQEDSELMMLLELRFRLLARLLPNCLNDDMGLVAFMLARSDLLSWTADLLVNDSAEEIQKQYQLYDGLLDFIEALANHPATTQLVKQARSIYGDGGRLHRISFLKLRNIGSEANAVDTTGKSLESMLQAIFERNRKTLEYNRKHNLHRDATDNTIANMQAWDSRISKIVQTYRVKAVVRSMANLRIDPAPAIQTFADYHRENGLAEVSDNLILYSHHYNVAATKASTGQPPRQRMKRVIREITTLQSSLPEGVFVRHGSSRLDVLKFLIIGPKDTPYADGFFLFDMFLPLEFPQKPPFVRFRTMPCSTNHQNEGLNPNLYSSGYVCLSLLGTWSGEPWRPEQSTLLQVLVSIQSMIFCAEPYYNEPYRCKDDAKSQKYSKRIRQMTFDCAITPWIEATANAHGGKLSVARGPGQSNVDEMWKDVAVHYFGKDSEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV60</accession>
    <name>A0ABR1UV60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxylic ester hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661420.1">
        <property type="nucleotide sequence ID" value="XM_066819232.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052292"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="54371" checksum="0BE2A5ED669674D6" modified="2025-10-08" version="1">MSASYWPVDSHTSHQYPHDGSQFNTTVFSDNFPLHNLPSYDQSGDTRSYPVSSGAKGEDGIKLRAPKGRLPSLWMWELMASAFSLICIAVVVVVLLNEDGKRLSGWALVISPNAVISFITTLAKSSCLLVLAEVIGQLRWVHFATAPRRLSDIQLFDAGSRGPWGALQLMFRMKTAALLASSASLLTIAALVIDPFAQLVFSFPTQATRTTHQVASIRLAPVYDANTSVTANHGIPYPNAPFQLQSAVISAAFGVTPRFDLTCSSSNCTFPPVSTLGICSTCQDVVDATNTTCGRDRKSGATVCNTTVPRQLLPPSNFTWSVSSDAAGSYANVWNSSSAPVTPSMVTSMTGYGQPAVLAAFTALKLDRSLFSGHADRPTKPSQVNQCMFAYCLKTYSNISVDSGQTDVGPVYETIMHISSHEFFLDPPRNPKGNFLFTMQAFADGQTVGPNYTMNWFDHLNLGMYMKDVLNSTVVLNTGTYQPGDGGRMAPRSAWPCTMRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVU9</accession>
    <name>A0ABR1UVU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661646.1">
        <property type="nucleotide sequence ID" value="XM_066819458.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052518"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8063047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="17766" checksum="C32003DB8AA05721" modified="2025-10-08" version="1">MGLRNGQNDPIDHQAGPESKHHWSEVIDAQPPDRPEQRPAVSFTTPNQASDSAPTATPSSAYPPLTAFAAQDCPAKNGLLYRDPGAGDLSDSYLIVCDTYFGGGSGKAPSATEDVARRPDECFGLCTQTKDCVGAGWYNDTGSIFCTLVSAFDTTLKAPGYIFGMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVY0</accession>
    <name>A0ABR1UVY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661682.1">
        <property type="nucleotide sequence ID" value="XM_066819494.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052554"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8063083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="151" mass="16554" checksum="59EBBE990D218CF1" modified="2025-10-08" version="1">MQPSGRPGRYSRLTKDFADPSLPAITCPNRTESSHAGSISSAHATKEKRTEKADTGYVKRLTGDGLWRSMIDGIAFLICYAESASQSNAGITGAGSNAYIRRDWAQRSVKMGVHPVRIIRDLIMATWLQPLAGRAVSVTGRDWAKDPWFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UW01</accession>
    <name>A0ABR1UW01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014322</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660824.1">
        <property type="nucleotide sequence ID" value="XM_066818636.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051696"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07627">
        <property type="entry name" value="BAR_Vps5p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035803">
        <property type="entry name" value="BAR_Vps5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="168"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="569" mass="63281" checksum="252440073C05CF34" modified="2025-10-08" version="1">MDLGEAGDSPWGDVPSQSSKPPFEQDDSVLKTSETDAPQASQSNVKPAAVRGPRKPVRRLQAQPTSLQADDPLGPLGPLGDNAAPGADAQADEPPVPPQKEQMTIRTTMPAAGQRKAGPKDPHNIDDEEDADLPTGPRAPPPVEAALPSPIRTTNRPSISLEQAAAKPSFHISVGDPHKVGDLTSSHIVYSVRTRTTSKGYKQPEFEVKRRYRDFLWLYTTMHGNNPGVVALNRFDQSFVESRRAALEKMCNKIAAHPTLQNDPDLKLFLESESFNVDIKHKERREPIPGESKGVFGSLGISVGSSNKFVEQDDWFHDRRVYLDALENQLKALMKSMDTMVSQRKAMAEAAGDFSASLHALSTVELSHTLSGPLDALSELQITIRDVYDRQAQQDVLTFGIIIDEYIRLIGSVKQAFGQRQKAFHSWHSAESELQKRKATQDKLLRQGKSQQDRLNQVSAEVADAERKVHQARLLFDDMGRLMRAELDRFEREKVEDFKSAVETFLESAVEAQKELIEKWETFLMQLDAEDDETVFYRPPVIQTAGDKARMPGDTAVDRARATINDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UW31</accession>
    <name>A0ABR1UW31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660854.1">
        <property type="nucleotide sequence ID" value="XM_066818666.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051726"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="148" mass="16048" checksum="2F14ACDF099764B8" modified="2025-10-08" version="1">MGVLTGCTTPASTPWRGHSTRRSSTPSQEFQTKVGLTGVERDPDVKRFYAKCAMWQIRRKFAQMCLMFPRCPGCFLPAPPGMLLPPSVPVRTTPGARPTWTPAGFTPRSGTSAASSGPAVTAFNRVMVQSQFVALLEVFGNQGWPFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2E4</accession>
    <name>A0ABR1V2E4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012111</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIM50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662117.1">
        <property type="nucleotide sequence ID" value="XM_066816425.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049485"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FCP1 homology" evidence="3">
        <location>
            <begin position="114"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="304" mass="33895" checksum="F0E3E26395AAE083" modified="2025-10-08" version="1">MASLLAQHGTEAEVTPASNPGNNAVLNRAENGSANLSHLPNKPPPVQGYVPPAKRNQQKKNQGQDQKQKQNTQGISKETKDVRPYAVPSKASGGVPNPSAQYMANSAVPPSHLPEPRRILVVIDLNGTLLYRPSRKNPSRFVERPHTRAFLDYCLNTFCVAIWSSAKPDNVHKMLNQLLAPEERAKVVAIWGRDTLGLSPADYNGRVQCYKRLTVLWADLARRLGQRWDQSNTVLVDDSSEKARSEPFNLIQLPEFEGDLAEQGFVLPQVHDFLNECAKQRDISSYIRAKRFAFRPDFILAAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3D4</accession>
    <name>A0ABR1V3D4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662420.1">
        <property type="nucleotide sequence ID" value="XM_066816728.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049788"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF11">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="36609" checksum="201F153CB28584BF" modified="2025-10-08" version="1">MASPTSRISLFVEAIRIIPPGASMGRRDELGTLNRLTDDRVAAAARNEIKTGQRISLNWPLDAQSDRSFFQRALFHQDIFPKAPATVNDDVWTFNSQVSTQWDGLRHFGYQKEKLFYNGVTMKQIHGFGQEKGKKSTVNGIQAWAEQGIVGRGILVDYHSWRTSQPDGKVSTYDSFYSTSISVADLKACLDAQATEVKFGDILFIRSGFMAARATKTPEEIWAHQDVMPHRFGGVEQDEAVLRWIWDNFSAVAGDQPSFECWPTQKDWLLHEVLLGGWGCPIGELFDLEALAKRCRDEKRWSFFVCSEPCNVPGGVASPPNILAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3Q4</accession>
    <name>A0ABR1V3Q4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662575.1">
        <property type="nucleotide sequence ID" value="XM_066816883.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049943"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="334" mass="34778" checksum="3DF5EAE2E65754DC" modified="2025-10-08" version="1">MPLPVPVDVSVNASVSAAGALVPAYATDVCLNVNDFSSACRCAGVRPTTITATAPSATLTVIKGAQVTETTQVDSTASLTTTATATATQTIVVTEMVSLTITVPLTSTVDQVSHVLLQSMPASYWYYPPTSHAYNASGETMLTDDDFPQTDTTTALATTTTEVLETTATVVTSTVTPAPSNGVLTVQGSRFDGTYARIVFPDDDNENASDHQAVRAFAAQSIEATLVSITDEGGLSVFGYEAASPNSRMAILFFEPSYRIQSGSLFALVCASAPVTGLVTCTRNLGGGPSPVVFQQCEALADQETNGAGVVISDHEEDGCETFEFVLEPQVSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3V9</accession>
    <name>A0ABR1V3V9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8064970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661724.1">
        <property type="nucleotide sequence ID" value="XM_066816032.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049092"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8064970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="144" mass="16447" checksum="63710BCD16B63B20" modified="2025-10-08" version="1">MLTLAPFKPLNRDAVMLVIGRQAPRGWKLVDSEPIANANSGFPAVFVDDRFTKFVVPVNVRLNQDGIDIWVLVVVRRKPGEADPSANVWAVDFYDPNEPEMEENQFGHHDRRKRHLKVVKAMAKRWFGDELQFDVPPSGSLPLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V581</accession>
    <name>A0ABR1V581_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CWF21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012814</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662820.1">
        <property type="nucleotide sequence ID" value="XM_066817128.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050188"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21372">
        <property type="entry name" value="cwf21_CWC21-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013170">
        <property type="entry name" value="mRNA_splic_Cwf21_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08312">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01115">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CWF21" evidence="8">
        <location>
            <begin position="50"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="168" mass="19213" checksum="0BDF8633DB9AE49F" modified="2025-10-08" version="1">MSDNVGLSTPRGSGTSGYHTLSRATGDRGAPYAARDLERHRQRQPDKGILEHERKRAVEVKVFELRDKLEDEGVDEDEIDKQCDAMRKDLLAKQEKNQGGTEPRKGLKMHQVHELADAKIKESERLRNALKISKDYEEGGHWKRQEERLRKAVDRDNAADRDKEGVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5E1</accession>
    <name>A0ABR1V5E1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662233.1">
        <property type="nucleotide sequence ID" value="XM_066816541.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049601"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25746" checksum="9894EDE32AC87A4D" modified="2025-10-08" version="1">MDEARDTRPSTLEGLPVELVRLVLAGLPDVASLQATVLSCPLFYGAFQEAEAAIATQVLLNQMDASVLPEAMAAAESTRLRLHPDAEPLAEMAVAGFMDRNLRNRPAPPTSWSLLDALRVARLHAAVEEFAVRFANEAMATPRLSPSRSIDVTCQELCRIERTLYLFEIYCNLFRISPMLLRSPGMSMRIRFYREQQRLFFTNFAPWGERAAGMYPRLSSWGHIARSVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V647</accession>
    <name>A0ABR1V647_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662216.1">
        <property type="nucleotide sequence ID" value="XM_066816524.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049584"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045987409" evidence="1">
        <location>
            <begin position="22"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="109" mass="12298" checksum="4498EA75E8B5A003" modified="2025-10-08" version="1">MVKLSTLAVTAVATLAGFVSAKDCNEGIQYCGWDLEGWDYNKYTPIMNRLLIAAGKDIEKEKYHSLFKCIDDGNDLELGDFCGDERCEKMTSKYCDYGHNDCCIIKNTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6F5</accession>
    <name>A0ABR1V6F5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662654.1">
        <property type="nucleotide sequence ID" value="XM_066816962.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050022"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="171" mass="18575" checksum="F1C5B2292FFE800B" modified="2025-10-08" version="1">MLGETETKPPLYAVSFHAGWTGPDVELHSGLNETDPPLATAKRGSLIGGDSATIKLPGPPTTAATAAARPSRNTYDFTIEVGGQREKFEWQHVGMRTGWQLARLSTNEAVAHFEWTNLTKKELYFQFVGSGLIGALGERWAVMAVITAIRAWDRVRRRQGSGTTAAIVSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6G5</accession>
    <name>A0ABR1V6G5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663547.1">
        <property type="nucleotide sequence ID" value="XM_066817855.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050915"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="262"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="476" mass="53231" checksum="EF2832F65F7B174D" modified="2025-10-08" version="1">MPICSDCQLLALWTFQGPDPGLSYYERPLDVRLSDFPEEKVAWRNRSWPHRRFLLSVFELHLQPAGCALCRWLSESLPRQTAKADFVDRMQARVAAKRMEATHLLPPPSDETQSDLWATLPQTIDYDLPVAIFTRPHCWNTYRAAPGILCLGAHSQLDMINNDFGDADRKKSIAVVAEGERILHSAIWSTKPVYFEDRAHTIVSWLRTCSTDKSDKHAECAAPAPPYPARFLDVNTSLDDRFIKLVRSGDVAPDPSTSRIRYLALSHCWGSTTTKPFTTAKATLRDRMSGIWISVLPKTFRDAIRVARVLEVQYLWIDSLCIVQDDLQDWTVEAAKMADVYQGSYFTIAATSSPDGDGGLYLDSVTPATRVDLRRAKESSKPSPNTSNAEPPDACYIRYPVASPDTIRSGPLSSRAWVLQEQMLSTRLVHFTDSQMFYQCAAGLSSEDGVLYNTATRSRGITKTGNGKSVPNGGCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6S3</accession>
    <name>A0ABR1V6S3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663631.1">
        <property type="nucleotide sequence ID" value="XM_066817939.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050999"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="561" mass="61928" checksum="8E464BB00C709F2D" modified="2025-10-08" version="1">MSSQNFSDGTAASGGRDLVLYDEQRPLKPKRGPDKQPRNRHRTGQLTLSKYFIFPLARSIDYWFIFFFFFSKSHQTSYECKSTSLTLKWEELIRTAAAPPPASIEDDSPPTIDSRRAWIAMIDVAGDIIKSVPRSLDELQCRSDALRVPAIRRLFHMVVIYRWIPSLSGKTVLPADELVGVWHLQRSLEDDAMLEAEICSELHVGSDRLRSHEDHTAYLGCLTRSIARLRREIRAIGAGAGSGGSGGPAMLSDPALMTAYVLAMSGAHVKEEPVGTGLFGDPILLFDQSRSGGHLKAFFRSTHFAQVRSLAMRGGAKGMKVPDLLAYILMLYASYQLIPPGFAFPEEQLLIVAQGVESCRDIVAKSTDVLLAADADFLYTVHCTRVLARLSEARDDVLGKAKYASLRTYVGVVQHQLLNIRRADPAIEIYMLGALLFAYGAIGYVIAPDCLQLLAENLVDALEAPRYTENQPPELLFWAAMLGAMGSAPKPGVVMKPVDRAAIDCLRTSKYLIAKVEALARILGLKTWEEVKVVLEDFVWAGHNCDKGAKYIWDLANPVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6Z1</accession>
    <name>A0ABR1V6Z1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Importin alpha re-exporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013721</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPO2/CSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663727.1">
        <property type="nucleotide sequence ID" value="XM_066818035.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051095"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005043">
        <property type="entry name" value="XPO2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF8">
        <property type="entry name" value="EXPORTIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03378">
        <property type="entry name" value="CAS_CSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="24"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="951" mass="106623" checksum="285908A6F028986E" modified="2025-10-08" version="1">MASDLGQLVQLLDATLDPSKQKKAEKGLAAEKANPRFSLSLLQIVHEASLPLKTRLAAALYFKNFIRLNYVDSNGNYLLGPDVVSTIKQELIGLMIACPPTIQTQLGDAISLIADSDFWERWDTLVPDLVNNGVLEVAHSIFQRWRPLYRSDDLFTEINHVLGTFAAPFLTLLNATDQQITANANNKEALKGYFDTMSLLVKVFYDLSCQDMPPQFEEHLEQISVFLHKYLTYENPLLATDDDSEAGVLENVKADICEVLELYTSKFDEEFGKYTQTFITSAWNLLSSIGPEQKYDGLVSKALHFLTAVAGTARHAQNFNDENVLNEVVEKVVLQNVALRETDIELFEDEPIEFIRRDLEGSDTDSRRRAATDFLRTLQEKFEQLVTKVAGKYINHYLEQGKADWKHKDTAVSLFLAIAAKGAVTAGQGVKTVNSLVNVVDFFQQHIAADLINAEAEPIAKVDAIKYLYTFRSQLTKEQWQGAFQPLIQNLGSSNYVVYTYAAIAVERVLFLTNDSGVHLFSRVDIEPFAKDLLQHLFQLVEKEQAPAKMQENEFLMRCIMRVLIVMKDGVLPFADMVLEHLVAITNVIKENPSNPRFYYYHFEALGALVRNCSSGASAKLEERLWEPFHKILVEEVNEFIPYVFQLFAALLEPNPSGALPNHFKALLPPLLQFTMWETRGNVPGCTRLLSAIIPRAADMIVAENQVEPVLGIFQKLLSGKKTEQNAFDILEAVVTSIPRAQIEPYFVQILTLLLKKLDLDPQESYKKRFVTFYHLVSAKLEAGLGADFFISQVDLIQSNLFVPIYLKTILPISQQLIRPIDRKLAVVSFAKTLAESQAFAQRYQKGWGFTCEAMLPILANVVQVAAAGGDDVVQEADVDDIGFGMGFTALSTCKKPARDDLPEIQDAAQWVRGYLTQANAAKGGVISQWSAERVPSPEGKQNFIAFMNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V762</accession>
    <name>A0ABR1V762_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxin 11C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662848.1">
        <property type="nucleotide sequence ID" value="XM_066817156.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050216"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="359" mass="38424" checksum="73C5EDD4911FD88C" modified="2025-10-08" version="1">MSSAEVEVDVGAEVEAGVEAGVEAGVEHGVEAGVETGVETGTESKGEAVVETPGEATSDLPSGDPVPSVSSGPAPEPKPMPIKAVLAATPSNIDVFLAHLQRCLSTPSGIDTTALFLCYSSRLSAAVLESLTGPAVQRSASQLIAIASALPPYATLLFTAKSLPSFSPSAALLLNIAKRLRAFGGMLSEARTFLRLWGLLNMYFWARGLIMRLRAARQQVKDEKAAGGSAKLDKLEVSFSVTQLVACIIFQSLENGAYLAQKGVLSWQPANIGKLFYSAYRRSQRTPAERLGDRTVAVMEQEESAWTDEWRKTVVRQLAWFPLTIHWSLEQGLFSEMTVGAIASIPGVVQMRDLWAKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7L6</accession>
    <name>A0ABR1V7L6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA(Thr) (Cytosine(32)-N(3))-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013933</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663939.1">
        <property type="nucleotide sequence ID" value="XM_066818247.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051307"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF11">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8067186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="224" mass="25291" checksum="AF18D4C7E3A3369D" modified="2025-10-08" version="1">MASAAACELPPASTEQELADKASTLALEEQGVSPAVEAAAATSLPPHRSHDPQHNMKRTDPFQFGSRFLQQDDNVFEFNAWDHVETDDTYKEYAEEQFQKQRESPVSDFDKTRFNSDPAKWWNLFYKNNTANFFKNRKWLQQEFPILGKVTEEDAGPVVVLEVGAGAGNTAFPILANNKNPKLKVHACDFSKKAVEVMRGHEEYNTEHMQADVWDVASDELPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9I4</accession>
    <name>A0ABR1V9I4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Benzoate 4-monooxygenase cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_013698</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663704.1">
        <property type="nucleotide sequence ID" value="XM_066818012.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051072"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11059">
        <property type="entry name" value="CYP_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF164">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="517" mass="58026" checksum="D041D5D3B30ED7D6" modified="2025-10-08" version="1">MAPMPITEVSLVALTFLLIYSLVLHPLLFSPLAKIPGPKAYALTKWRLAYEDWRGTRTRAIDQLHQRHGPVVRTGPNEVSFNSLGGLRAIYGPGSPYGRTSFYRMFDVYGRQNLFTFHSAAAHGRRKRLVSHAYSKTVVVRGPVAALVEAKAAEYMKLLGAEPDGVSDVFRTLHYYSLDAITAFLYGRHGSTSAMMEEEGSKFEAHRALIGDILDPARRRLSWFAVHWPGLTKWLYTRTGWAEAMVRPLLPMRKPATYTGIRRFALEAYRRFEDDAKRGVVNDESPGGLDDLDIASECADHLLAGIDTTSDTLMFLIWALSRPQNQRFQDRLRDEVRSIPETSLSVTSSSTGIPTVETSDRCTYLGAVIKETLRLYSPLPAYEPRSVAAESAIDGYTIPANTTVGSSPFSLHRNPDVFKDPLVWDPERWLSAEEDPETLAEMNRWFWAFSSGGRMCIGLHLAMAEMTTLTAAIYRKYRTSLPPDFEDVAPGITSRFEVFSDDRFSKVAVSWLVLFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAP6</accession>
    <name>A0ABR1VAP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664154.1">
        <property type="nucleotide sequence ID" value="XM_066818462.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051522"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF3">
        <property type="entry name" value="BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G07500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="25"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="47509" checksum="529E1C885FA14B0D" modified="2025-10-08" version="1">MPFSAASLERLGSIVDDSCKDSTSGIPGTTVVVVGKDGEELFIKAAGRRGVDSKEAMSLDSIYYMASCTKLLTGIAVMQLVEQGKLRLDDAHQIEELCPEFKTIKILRLDSGSRPSAPGRTPETTWRFEDKKVGITLRMLLNHTAGFGYAFFNERLRDWCLAAGVNVFPSKFEDVKMPLLFQPGEGWEYGTGVDWAGIALERSTGLSLNDYLQKHVFAPLEIREMTMIPTKEMRSRLAHMHARGKDGSLTTRHHLLRTVLDIDLDDETQKKPALDNARRAKSEPNTARSVEILAMLLNDGTCPRPGAKILSKDTVEEMFRNQVPEFPGLGRQGIPAAVPELTNPVPDLYPVEGKPPQGWGLTFMQSNGGATGRSTGTGHWAGLANTWWWCDRENGVAGMVCTQILPFADPAVLGLWTQVETETYKALKEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGR8</accession>
    <name>A0ABR1VGR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TAP-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010642</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664247.1">
        <property type="nucleotide sequence ID" value="XM_066814957.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048017"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045397990" evidence="3">
        <location>
            <begin position="27"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="4">
        <location>
            <begin position="498"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8070439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="620" mass="67111" checksum="54F14FF5722DBCCE" modified="2025-10-08" version="1">MMRQPHSGLGLSVLAGLLALSTTAVAASIPAISDFEWNTVTPSTSLNYTSCYDQTYNCAKLVVPLDWLSSESLPDNYQDGNAAVVTLAIIARPATVSQSDPRHGGTIIVNPGGPSGSGVGFMLRASELVQRTVDIDGDDDEELSAGGGCHYEILSFDPRGVGLTEPRADCFGGDAFARGKAWWTDRGLGAGFGKLCEAKNDAAGKEGGFGGFMSSSSVARDMVAIVDKLDELRRKNLAASTAATVRTETDGEEAQRRIELRSSGHGEPDSTPRIQYWGFSYGSALGNYFASMFPGRVGRVILEAVEDVNDYHSASWHVALQDTQHVLDHFWDTCFRAREACALYRPSDPAAAAIRDRVRSFIDALAAKPRPHDVLDAILRPLYQPQRDFPALARLLFEAMQGNLTLLYSSLNQATTHKDSCKDSRPDPPAYTWGPDAMTAIACGDGESQENLTAIEFADYVSDLQRHQNADFAFLEAQVRLGCCGWRIRPKYRFDGPWTTPHADAQLVSEKPAAPILFVSSRYDPVTPLANAVAMSRDHPGSRVLVQENAGHGSLFSPGRCREDYIKRYFATGEMPPEGAVCEPDCEPFQECLRMGGVGALAVGDEAGDIGGWRGPRAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH07</accession>
    <name>A0ABR1VH07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664230.1">
        <property type="nucleotide sequence ID" value="XM_066814940.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048000"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="336" mass="37261" checksum="F1D5D8AE803784CC" modified="2025-10-08" version="1">MPMLYCKFCQRGCDALCFDSHRSRYYCHDSRCPGSEPRGSDRDRGRSSSSSTLRPEPPSRPPSRSSSSTLRPELSRSSSKRHGGHSSRSSSVRRTPERECRESISRSATPVNGGSGSGMCHSRDARTGERFSYPRNPHEDRDHMRICAKYPPPKRGCRYGYDGDGNVVSFAVSREADDYCDPADIDYRREQRPERPPSRSGSYRSGGGGGSGGGEAGIPRRSYSTRGRDYEDRGSGGLGRSYSTRDARPHDIDPGREGLGRRPSMSRRYPSSRDEYAYAAGGGGHSYDSSRPRYPPGYMNQHYGGGSWTGGTGPPAPPWARRPGRELRRRSRSVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH87</accession>
    <name>A0ABR1VH87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664392.1">
        <property type="nucleotide sequence ID" value="XM_066815102.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048162"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="384" mass="42209" checksum="05F85C259EF22B83" modified="2025-10-08" version="1">MILRSSEDQAVFLMVTTNPCQDLAAYRDNQDEVSPGRPIVEPLRRLMPPVNTTSCPQLNLPGVTTLPGYHSVIAAVCFSYPSIQHYKGSITNGILKEEIVGDPHPLSPFDSSDTLGGMVSEGLWNYGFSDHCLINNVLYTNASSNLSSVPGGFVTIGNFEAPKRCFYGFNSNWHIPLNNGGARNGLSDLITGGFSDDTCHGSNNLTNMVCDHAWWLGNMFNGGNAIIRSINAFLDAGFRSFTNQLRTYGTDWHNNNLVANGTVMETTVCTQFNWVWLVYPLAILVGTLVLFIATFISSSGMFGHVKETIWKSSVLPLLFYGLEAQHKRDGIRLATANELTAVAKRLKVDFSARDGGWRFHAVDGESADGRPQEESELEERGNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHB6</accession>
    <name>A0ABR1VHB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyl esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664391.1">
        <property type="nucleotide sequence ID" value="XM_066815101.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048161"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="351" mass="39032" checksum="63065F48DAAE2847" modified="2025-10-08" version="1">MRPLPLLAAAGTAVANYPTRQHTVKNVIAFGDSYTDSGRISAYIANNGSAPPPATDTSTSNFTAGGGYSWGHFATQQLGAKFYDYAVSGAFCSNTIFERFLPQINRSFPSVLEDQIPSFVEDVAYVNASTGSNTFYPNRAGANTVYALWIGTNDLGSFLTDSQYAGFTITDFVDCVWRVFDAIYRQGGRRFVLLNQAPLERTPLYAAPQRGGAGDNQYWPTKTQNCNSTQVEQKVLEYSTNVNTMFDYGVPFQLLVNKTRRWPHASFTVFNVHELMLDIYDKPEQYLDAPANVTGYYHHCDVNGLNCTNSQNPLSSFMWYDELHPSEKTDEAIGKEFAKVVGGKSSYATYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHM5</accession>
    <name>A0ABR1VHM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase/adducin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664547.1">
        <property type="nucleotide sequence ID" value="XM_066815257.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048317"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF39">
        <property type="entry name" value="CLASS II ALDOLASE_ADDUCIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="74" mass="8079" checksum="3914C312150365F2" modified="2025-10-08" version="1">MHFSLIKVSDLILVDEDGLVVEGEDPINTAAFTIHSAIHRARPDVNAACHAHSVHGKAFSVFGRELEMITQGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHN4</accession>
    <name>A0ABR1VHN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Clr5 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664470.1">
        <property type="nucleotide sequence ID" value="XM_066815180.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048240"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="87"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="381"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="827" mass="94247" checksum="15D11BA61807FB5F" modified="2025-10-08" version="1">MAAPGLILRPHWSPRNDQGELHRTKSFDPPQPTRPRLFVLTPSHQFICKEATDSTAHPDGEPRFPAAMDPTRGGMATMDSQSKWAKPEDWAKYKNTISALFMCHSLPNVMRIMREDHEFHATPKMYQVHIYQKWGLRKGRPEPKSNKKRRRAPTEEPEESVASSSHTNTYSNLQSNAQSNAQSNTQSNVHSSALTNALSLDNVNSRLQLPVQDFDTADDMEHTRALQLVEQQHAQLYDRNTWAREPISYHEGDYRLRQSPPRYIRPPEGTDEGDDLVQASSAGHSNETRGRFGPALRHVVTAQNQQVVPPETWQDFIGTSHLDPAYQNTTTLPQRGAPVPSYAFSEMTDPSVDDSGTWMSTVLDQTQPSSVTASTRFSNKSAKTGSGQGSGASQASSRSRVSRGSHASSSRETLLSTGSSLSFKSKTKSNSSRSTQSRMTLPTGTIRLMASPDTLMFSEKSMFFARHYISSTFSTGLWTLSQNTDTSLLDTECVKLDAWYNDFNPGFEFLYENRSNQPDRIKRAFCIFQRCFAATEYIIEPQDPRLVIYICQQTIRFMFYDTVGRNLAQTFLRYVSGLCKKMFGESHPLYIIMSQLARMDQFEFAQNVPALMECYFDHLEPFLGEETSAFGFVNDLRGLTISIMEATGMMGLYEAKPIIDRLVKRAEKLGHNRLHLMIEQAAIFQRNRYYMEARNMLREIRNSQEGKNDPYERVYASIVLMVVFRKMRDSDAGIHLGYEMVDYIENFERRRDMPEFNYELFKGLGPSTLMIFLGKLEVELREVQRYDEADEVKAKMDQVMNSQYEYNVNQQQEGLDQNTQNTVATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHS1</accession>
    <name>A0ABR1VHS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010967</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664572.1">
        <property type="nucleotide sequence ID" value="XM_066815282.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048342"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="334" mass="35554" checksum="108B7CC1EBD6A2A4" modified="2025-10-08" version="1">MAGELVLLTGGTGFLGYTILVDLLQHGYRVRVAVRSHEKIAKMWAAPSIVALDPRATQLMFVIVPDMAAPGAYDEAVQDVDFIIHTAAPLHADHASAVGGSDPQKVQSLEDAFVTACVQGNLGILHSARDKGKSVRRIVMTSSTVAIAPADFFSDAAAAAQMERGEEVIRGPETRVPVPEPPYNSQLPAYCAAKTASLEAAETFVNNHALRFDLISIMPSLIFGKDELATGTDSTRMLMYRLLPQPASNGPGDGDAASNPYQGEIVAVGNAVLCTDVARAHVRALDPDVKGNQSFVLNTDARWEDTVPITKTHFPSHSTRGCSGRVVRSGPLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIF7</accession>
    <name>A0ABR1VIF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_011191</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664796.1">
        <property type="nucleotide sequence ID" value="XM_066815506.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048566"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF43">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="13">
        <location>
            <begin position="230"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8070988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="531" mass="61011" checksum="5279D961493FD657" modified="2025-10-08" version="1">MPWTWIKSWSGNSVTLGGREVGLNLRMRRMLWLVFAAVGIALLLYTIYISDTHRSFGYTIGSFQHSKGETPEQASPSEDGSGRPKFLPWETTSSFQPVSFPDIGAVTDDDLCRSFPQQKLAHLVQPVLKFGHGDQPARVESQLSSVSACLQDLLIFSDYEETISGRHVYDVIATTPASYRRDNPDFINYLTLHGLNENGTALKPGEPRPEVNGWIIDKYKFLPMIEQAWALRPNKRWYFFYESDTYVVWDNVFRLLENLDADTPMYLGSPSPGRHTDKDEVTFFANGGPGYALSRGAMKKLLARKVGKDGDYVEAPLSHRWLELLRHECCGDSVLGWALFSAGVAISGLWPMFSPNAPHNIPFGHRHWCQPMLTMHKMKPEYMVDFWKWEHVRRNRDTPLLYRDAWEHEHAEQGLASREIAVDWDNRGWGEYQTAMFKDYNECAKFCVEDTRCLQWLWHLDTCRLAEAAVVGVPRSPEVEGDAPHLPEGQTWTVEQSRFVSGWNMERIERFGQENNCEVVEWLRPSTTRMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJI7</accession>
    <name>A0ABR1VJI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Methionine aminopeptidase 2</fullName>
            <shortName evidence="9">MAP 2</shortName>
            <shortName evidence="9">MetAP 2</shortName>
            <ecNumber evidence="9">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_011581</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="9">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665186.1">
        <property type="nucleotide sequence ID" value="XM_066815896.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048956"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01088">
        <property type="entry name" value="MetAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03175">
        <property type="entry name" value="MetAP_2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050247">
        <property type="entry name" value="Met_Aminopeptidase_Type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777:SF2">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="12">
        <location>
            <begin position="132"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="20"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8071378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="48499" checksum="9B9ECAD5A87EF5FC" modified="2025-10-08" version="1">MAAQAPVDELKKLSVSNGADAADAKAAAANGAAAAEEHSGGEDSDDDGDDAAAGTAEGAAKKKKNKKRKPRKKKKAPTAQTDPPSVLISTLFPNNSYPAGQEEEYVDENRYRTTSEEKRHLETLNTEWLSDYRHAAETHRQVRQWAQKNIKPGQSLTEIANGIEDSVRRLVGHDGLAEGDAIKAGMGFPTGLNLDHIAAHFSPNAGNKTILQQNNVMKVDIGVHVNGCIVDSAFTMAFDPMYDNLLAAVKDATNTGVKNAGIDVRLGELGGLIQEAMESYECEINGTSYPVKSIRGLAGHTIHPYSIHGTKSVPIVKTSDTTKMEEGDVFAIETFGTTGTGHVTDSGEVSHYALRQDAPKVDLRLNSAKSLLRVIKNNFSTLPFCRRYLDRIGQEKYLLGLNNLVQSGIVEDYPPLVDKKGSYSAQWEHTILLRPTVKEVISRGDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU88</accession>
    <name>A0ABR1VU88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009478</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665755.1">
        <property type="nucleotide sequence ID" value="XM_066813793.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046853"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF287">
        <property type="entry name" value="MFS MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="506" mass="54330" checksum="F225EA7B0A1BEA9E" modified="2025-10-08" version="1">MSSTPTELVAVARPLPDRQLEDSSAQESQISIQQEPDHITLAHVDRLPPVDRGKDAYLFLAASWAIEALVWGFPFAFGIFQDYYSTHAPFEGSPNISVIGTCAMGLMYLTAPLTFGLCRIFARWARWTPIVGLFIMSISLAASSFCTTVPQLIACQGCLYAIGGGIAYAPCILYLDEWFVRRKGLAYGIMWSGTGIAGVVLPLLFEALLRSLGYQTTLRLWAGVLFAITAPLAFFIKPRVPVSRNTAANKARPFNFKFLLLPSFLIYQSANILEATGFFLPVMLLTSPFLPSDLPPHLRPQRLRLRVAPVRHDGAPGQRGLGRGLRRHGLADGPPARHDVHLAVDSRRRALRVSGLGPCLLAAGPLRLLSPVRPLRRVLHTSAWPGIMRAVMEKAAASDDAAAAADCTDMSTDANDHHNGSGSGSGSGKKKYGPVDTSMVFAWLAAGRGIGNVVSGPLSEGLLDGLPWLGRAAGGYGSGYGGLIVFTGVTACFGGASYIWRRAGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUQ7</accession>
    <name>A0ABR1VUQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665926.1">
        <property type="nucleotide sequence ID" value="XM_066813964.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047024"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051599">
        <property type="entry name" value="Cell_Envelope_Assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30336:SF20">
        <property type="entry name" value="DUF218 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30336">
        <property type="entry name" value="INNER MEMBRANE PROTEIN, PROBABLE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF218" evidence="1">
        <location>
            <begin position="53"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="232" mass="25964" checksum="AF4BF3566F77FE76" modified="2025-10-08" version="1">MVAETASASAAAADSSRSSLEVDAETVFEYHKMAMPLQRPVDAVFCLCSLDVRVARRAAELFLAGYGDRFLIFSGGVGRLTRGRFAKAEAEVFADIARGMGVPDEKLVVETRSTNTGENVRFVWELLEQRKVAVRSFVLVQKPYMERRTYATFKRQWPDPGTAITVTSSQLDWRGYPDADNPRELVTNIMVGDLVRIREYPAKGFQIHQDIPDDVWDAGQRLIKAGYSSHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV82</accession>
    <name>A0ABR1VV82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldehyde dehydrogenase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009828</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666105.1">
        <property type="nucleotide sequence ID" value="XM_066814143.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047203"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720:SF2">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="76"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="396"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="510" mass="55186" checksum="D9383554AEDF9579" modified="2025-10-08" version="1">MGSIQKGEDSSEFGSSVIQDVWLCDTLEKAEAFIASPHHASSSSDEGGRYKIKMQNYVGGSFTEPPSTSTTTATATSQYIDAVDPKTGKTFGQVPISSADEVEHALRAATDAFGPWSTTPAAARSKHLQRVAQLIQEHRELFAVWESIDQGKTLERARVEVDRAVSNFKVPQLRTAARVVDGANILTYEHRSPAGVFALISPWNMPLYLLTWKMAPCLAFGCTAVAKPSEVTSMTAFLLCEVFRRAGLPAGTMNVVFGDGATTGSALVRSPLVRGGVSFTGGTATGIQIRRDTADQIYKHLSLELGGKNPTLVFGDVEMDKAVQTAAMAAFENQGEICLCGSRIYVQSSIYDDFVAAFTAYVQANYKCGERVGAHLPLPLHREAPARGPGRRLLDPPTILTDVRPGSRLLQDEIFGPVATISRFATEDEAVRLANDNPNGLAAVLLTRDGARMRRVGERLEAGLVWVNCWLVRELGTPFGGMKSSGTGREGGEYSRDVFTHVRTLHMPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW87</accession>
    <name>A0ABR1VW87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010166</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666443.1">
        <property type="nucleotide sequence ID" value="XM_066814481.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047541"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="397"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="444" mass="47133" checksum="15080024A44D80FD" modified="2025-10-08" version="1">MPPIDPRGQHKGKREKICLGNLCVDFHITPAAAIATMQPEEESVAEEKDGLLMYPEDPDCKISLGDLCLNSHPAPAAAAADSPPNHEETAPPAAVSSGEAVVVERRFIPPHCGDPDGKPDPSCPFDHARLRNNGTRHGETQEVAAEGTEEGEMEEQALIPPFCKDPEHQDHRLCPGGRVEPIDHNRPPSALKMMFTLYPNITTTTAPTTPTLSRVDNGDAAASANATTTVDPNYKINQWEYDGRSMKWAICFLGAFGLFAAVVVFRDFRRKKFSWFPMPWDKPVLNAVANKLYRCKDKVRGLFSKGKGNNDEEGQQQQQLSEKGQGQAAAAAAGGVTVVATPATPAASSFYGTSAAPSAPSVSPFDAARQMEDGAANDNGSGSEGEATLSENVGVLANYNTPAAPAPATTTAGPAAAENNGEPPAVPAATFARPPRLPSLYVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX36</accession>
    <name>A0ABR1VX36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009066</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665343.1">
        <property type="nucleotide sequence ID" value="XM_066813381.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046441"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF2">
        <property type="entry name" value="SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="40"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="280"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="382"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8074403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="48878" checksum="42A496A146CE1689" modified="2025-10-08" version="1">MDAAAQAAAAMQEAILKAVHAAITEIWALYAVGSLLIASRLFVRIKLVGFRGLQPDDFLVVFAWMCYTSVSVVGQVFILNAGGKHTSQLTTPESRINLPLSEYPDYEFGSKMFLVGETLYMGTVWTLKMCMAFFYRRLVRGLWSEKLILPLMGGIGATFIAGIVTIYTTCVPVSKHWQILPNPGRNPWVFVTIMCLNLTTDLCILSLPIPVLAKMRTNTVRKIGLVFLFSLGAFTMVAAILRIISIFVLNQESAGALWSIREDFVAVVVTQAPMFWHTAYGSGDGSRDETSRSRSNRPRKKGSGHGHSTGESHELTFGSATMNRVKRPKDPYSLTQLGITRVGGSESQEEMINSPTNETTGATAGANGNAAIGSGVTAVATATTENSSDGKLGVSRTRSLSRKSRGPDKHQKNTVVVEQTVVTTTAICTEEQKRRDIEAWRKQPWET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXU5</accession>
    <name>A0ABR1VXU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_009382</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665659.1">
        <property type="nucleotide sequence ID" value="XM_066813697.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046757"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050081">
        <property type="entry name" value="Ile-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="32"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="11">
        <location>
            <begin position="670"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8074719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="920" mass="102546" checksum="B9924B7FFECB4CB6" modified="2025-10-08" version="1">MSKKWTATLRLPKSTFPARPLPQLKEQYVKRSADDYYEWQKSNRPADDQFILHDGPPYANGNLHVGHALNKILKDMILRVQIQQGRQVDYVPGWDCHGLPIELKAIEKSDGKQLSAIETRKVARNLATNTVLKQMKSFRSYGVMGDWDRRWTTMDAAYEIRQLRLFQKMVKKGLIYRRYKPVYWSPSSKSALAEAELEYRDDHVSNAAWVRFPIDESWRTHSPLAPLAESVSPATRLYAVIWTTTPWTLPANQAIAVHDDLDRVESSLAKVPGKVSSVTIQGRQLKGLKYTNPAQGKAGRPQPIIHADFVSADSGTGLVHLAPGHGFDDYEVCRGLGLPITAPINNEGVFTQEAYPDDPSRLTTAPSVIDGASQAVIDLLGQDILASEKYQHKYPYDWRTKRPVVIRATEQWFADVASIKDEALAALENVRFVPESGKNRLSSFVKGRSEWCISRQRAWGVPIPALYDSNGAAIVSEEIVGHIIGVIQERGINAWYMDELDDPAWIPTDLHGRGYSRGTDTMDVWFDSGSSWSMMPAQADVYLEGSDQHRGWFQSSLLTRIAAGAVEEGKKMSKSLGNVMEPHQVMDGTLLPPMKLKGKAAQGPPQYDALGADALRLWAASSDYTRDVVISVPVLSAIHTALVKYRTIIKMLLGSMHESARSAPLSATDHVAIVQLQDTMQEVEAAFANHEFYKGFNAINRWVNNDFSAFYLEALKDRLYCGDGGGVLEPILNGFLRMLAPMTPSLVEEAWDHRPNWLKQDTAALHPLQQLYNEPLVKPSRLTLDLDTVRSDIPVLMTVHAAIKAGLERARSDKVLGQSLQSSVILAVPDEAATVKTVLDRYAQELDVMFVVSSVNVNAPVDGQAAWKYEHEFEAGNGHMGTATVLPPRDVKCPRCWRYIAPVEDQLCGRCEDVVGETKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY78</accession>
    <name>A0ABR1VY78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009969</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666246.1">
        <property type="nucleotide sequence ID" value="XM_066814284.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047344"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050946">
        <property type="entry name" value="AP-1_TF_bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462">
        <property type="entry name" value="JUN TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="169"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8075306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="229" mass="24845" checksum="9D2CEB0B0F75EA3F" modified="2025-10-08" version="1">MTRASGTWTRPMTPPQMHGGFVQQAQHSPSSVSTGPPYGPPVAHLMGGQNQLETFPAFDPLGMQPPASPLIDSRKAKESDSTQPNPPGGSDPSAPGPPTSSRFQASTRSPKWYPLFPDAYTDPKDPNESGGTDPRKPLSAATPLLPPIPPFGPRERPLDDETSDVVGLKRARNTLAARKSRERKARQIEELKEKIARLEREREHWTEVAMSKSEQEPHKSSSASKAGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZR6</accession>
    <name>A0ABR1VZR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666288.1">
        <property type="nucleotide sequence ID" value="XM_066814326.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047386"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="56"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="476" mass="53134" checksum="6F673DF8F3005EDC" modified="2025-10-08" version="1">MARDYTTQDHDGEKASVDYVADVARSEHVVDSQEDWQNEFTPQEQRSIIKRIDRRLVTTVGVMYCVSLMDRTNLSAANIAGMDKDLALVGDRYSIITLIFFVTYTIFQPPSTVIVRKIGPRVHLALITLLWGCVMIGMGFVQDWAQLAGLRVLLGIMEAGFFPSCVYLLSTWYTRYEVGKRYSFFYILGCVASAFSGILAFGLMQMKGVAGLAGWRWIFIVEGLITCLLGIAGYWMLVDFPDSTRISWNFLGARERAWVVRRVNADRGDAETPKFDFRRFMAAGADLKIWAYAMIFFNTTTITYALAYFLPIILTVNLGFEVGAAQCLYHLRGPIIICNMVICLIGLPIMGWHKNPAVRYFGVFLVTAGANSNIPSAMAYQANNIRGQWKRAFCSATLVGLGGIGGIAGSLVFRKQDAATGYKPGLYACIACCLLTIILVCIVDTFFYIANKKADRGEKELEAHEDGYQPGFRYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8V7</accession>
    <name>A0ABR1W8V7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666952.1">
        <property type="nucleotide sequence ID" value="XM_066811610.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044670"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="63"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="487" mass="54932" checksum="711B8F048A17E47F" modified="2025-10-08" version="1">MSKSAASEDAYQFIYKHLQECETSPWAHENCTTGAFMPTRLVEISGPETFRVVQLPSATATRYTALSYCWGSGSFFKATKSTIYDLGKENNFCELPAVLRDAITITHKLGVTYIWIDALCIIQDDVSDWERESSSMGSIYEEAYLTIAASSSPSVHVPFLNCEFATKSACLQLEVPGMPEGTDLNIRARQRPLCGVHASYDNSDPWRRRAWAFQEQQLSTRLICFTPNELQWRCKLEPNCECGDVKSTVDWEFPWREPSSLSLTELSDFWHNAVFQYSSRDMTFPNDKLPAISGLVKWMSEWRVQDVYLAGLWKSTLINDMCWHRDAGAFTGTLPWVLPRLYRAPSFSWASVDGLVGYWHREKPIDPVRGDNERAQNVYPVAEVIEVECGFEVTLGRQHNPSRTEHVYHVRLDGAEIPFNADVNIDVVTISGSGEAASEIFGIRAGSQEYLAGESSQVAGVSYSRLTPDTEDCRVWLLKITPDAWGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAB3</accession>
    <name>A0ABR1WAB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008246</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667903.1">
        <property type="nucleotide sequence ID" value="XM_066812561.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045621"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF13">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="76"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="157" mass="17018" checksum="030776E0FF14C2E7" modified="2025-10-08" version="1">MERIEIGNYGNKGDDGSLGSQQRLKHSSEQHATTAITRHSTPRLRFQRTWVFLGLCAALLSARLLLPLLGSHKSLADLRPACVVQPVTAAQVAVVVRVLNHRNHTSVRFAVKSGGHDPNPGHASVDGGVLVALRHLEGVRYDVEKGVAYVKPGTSKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAU5</accession>
    <name>A0ABR1WAU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Xylanolytic transcriptional activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_008443</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the xlnR/xlr1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668100.1">
        <property type="nucleotide sequence ID" value="XM_066812758.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045818"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051439">
        <property type="entry name" value="XlnR/Xlr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663:SF1">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="95"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="133"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="529"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="151"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8080625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="914" mass="100562" checksum="3B90130D181F49C4" modified="2025-10-08" version="1">MLSNPLQRFSPYHSLPANTLLSNAHVPTSHLHAAGLDAFGHGSQYSLQHLQQHVGVHAPHLARAPQPKHRQHPYGGQAPRATGAAGPIRRRISRACDQCNQLRTKCDGQHPCAHCIEFGLGCEYIRERKKRGKASRKDLAQQAAAQAAAASTQSGPHKSEQQSTASEKALNELNEESTGRSQRTGSLDSLAEISSHQPHLTTHHATMDRDHLDSPTSLDLNGFGNVQNPYDRQGLGAHMMAGPTHTPYGASQTNLSDYPDIPYALQTQNPANYATNPSANFRMAASPLSAYPMAGETSPGWMSISSPPAQYQSHIPPPSYHQQLRYPVLNPLIPHLGSIIPVSLACDLIDLYFSSSSSAHAHPMSPYVLGFVFRKRSFLHPSKPRQCQPALLASMLWVAAQTSDASFLTSVPSARGKICQKLLELTVSLLKPLIHTPSGEASPVSSPPIDGVALGGLGVAMPGSMSLENLSGESGAFGAAGSLDDVITYIHLATVVSASEYKGASLRWWNAAWSLARELKLGRELPLSASMGQTDEDGNGINTSDDGEDELGGNIASGAVTDEEREERRRIWWLTYIVDRHLALCYNRPLFLLDIECEGLMQPMDDTEWQNGNFQSNVTDPALPGERVRGPHFECTGHSIFGYFLPLMTILGEIVDLHHARNHPRFGVGFRSAREWDDQAAEITRHLEMYERSLKQFEQQHFQSSAEDKNEQSATLEMPSELDHLDTVSVRSIRTNSSRMTESDIQTRIVMSYGTHVMHVLHILLTGKWDPINLLDDNDLWISSQGFITATGHAVSAAEAISNILEFDPGLEFMPFFFGIYLLQGSFLLLLIADKLQLEASASVVRACETIIRAHEACMVTLSTEYQRNFSKVMRSALAQVRGRVPEDLHEQHQRRRELLALYRWTGDGTGLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBF3</accession>
    <name>A0ABR1WBF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666948.1">
        <property type="nucleotide sequence ID" value="XM_066811606.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044666"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="76" mass="8199" checksum="3FCEFED689548215" modified="2025-10-08" version="1">MGGLASATAASECKMNRASSGTEWTVITSGVSDIPGTCGGLWDNLKRWGLACQVLYGTQYCRDEGNGELKWYFATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBR6</accession>
    <name>A0ABR1WBR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007774</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667431.1">
        <property type="nucleotide sequence ID" value="XM_066812089.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045149"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF2">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="18"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="497"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8079956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="57470" checksum="BC342433795967B3" modified="2025-10-08" version="1">MQRSHTPRNPENDFPTRQLFLLGIVRLAEPIALTSIFPYAWSLIKQFQVGKESDASFYAGLLISAFSLTEAMMGMFWGSLSDRIGRKPVLLLGCAGTTASLLMVGFARNFWFALAARALGGMLNGNIGVIQTMVAEIVTRKEHEPRAYSIMPFVWCIGTIIGPSIGGIFAEPHKSFPNVFGEDSLFTKFPYLLPNVICAVLLLSSIIMAYFLLDETHPDMAPRVTGNQTYVSEETPLFETSDSIKQPPFDIRSETYGTIRRSIEHQREMPCVKKTQKHKQPSIFTKPVMALICALSLFTYHSMTYDHLLPIYFEDDKAPDLQISSFNPLQSGGGLGLSMQNVGVILAFNGAMALFVQVVIFPIAASYIGIYKLFVTVTVLHPIVYAVMPMLVHVPESLLYPAIYCCLAIRNVLSIILYPILLILIKEVTPCSSVLGKINGFAASAGAACRMIAPPVAGYLYTIGSQIDCTALAWYGSTFVAIVGAIQCFSVKRPRCEDASEENPSGHPKRPSTTITEIDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCA8</accession>
    <name>A0ABR1WCA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EVE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668610.1">
        <property type="nucleotide sequence ID" value="XM_066813268.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046328"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="21929" checksum="D58C1C719810B851" modified="2025-10-08" version="1">MPSSSNNATRIMTDAVLPMRDPYMDQIINGTKNYEFRKYCLKPGVQRIWFYRSAPHSAITHVCEIMPARTRNPGDAALPENGLGNAEYNNRDPEWNGHDYAYKIMTVYELRRIIPLADMIKDYGFKIAPQGLGVPPPSYSASASTGVNKSSSSRMMMTIEGTMIPTGRIDDDTKGKVDDTSGRKDDTGERHGMNEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEZ1</accession>
    <name>A0ABR1WEZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008899</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668556.1">
        <property type="nucleotide sequence ID" value="XM_066813214.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046274"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8081081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="507" mass="57933" checksum="4150B0009A6C0344" modified="2025-10-08" version="1">MNVAVFSLIAVIGGWYLLRWMRTISTRSSPMPHVEFDGDKSRLRYARESEKLIARGYRDYLKKGQPFSMRNVVNHRRPLVVLPRKYLDEVRNAPQHEMSFPRFMENLSILRDVGGPLITDELCHATRVDLNRALPHLLKQMHEDCLAGCRELIPECSNWTSMMLYPLLLQIFNRIGQRVLVGPELGRNEDWLDLTQNYTTSLLQGTNSVRAKYAPALRWMAKYLERDVKVVYKQRQRGAALLGPVLKARLAARTEKLADSHDDAIEWLIDEYRRTGRKVKAEEIAQDQLGLTMAAIHNTAATVLSTLYDLVDHPASLDDIRREARQAMDQHGGINRAALQSLHHLDSFMTESLRMHAMPEVTVQRLALVPKTFHDGFRIAAGTQVMFANRQLNHDADVYPDPERFDALRFYDDPEELNNKQHHFASVSDESINFGGGFHACPGRFFAQDVIKLLLASLLVRYEFKYPEKGQKRPADMADNLVVYPNVTVPLLIKELAFGDISVSGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WF73</accession>
    <name>A0ABR1WF73_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008642</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668299.1">
        <property type="nucleotide sequence ID" value="XM_066812957.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046017"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="21881" checksum="7D96AB622C51922F" modified="2025-10-08" version="1">MAPLPSRHQRSKSRRGLCGRELHHLATHKRGITHPVFSEYIKITASGEEEVCRTSARRSRSSTTTISTTTRRCLCRTYAFPNRTSGIINAELLEVNTSLAHTPNLARSRWTRAWAACVLRNDTAIETNRYDFDTMANRTLYKLYISAAAPKSSAFVFPSYGTSVNVPLVHPGQRPQRPMGQCTISALGTLGDTPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL25</accession>
    <name>A0ABR1WL25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-ornithine N(5)-monooxygenase [NAD(P)H]</fullName>
            <ecNumber evidence="4">1.14.13.196</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_005480</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-ornithine + NADH + O2 = N(5)-hydroxy-L-ornithine + NAD(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41512"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-ornithine + NADPH + O2 = N(5)-hydroxy-L-ornithine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41508"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.196" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668718.1">
        <property type="nucleotide sequence ID" value="XM_066809795.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042855"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025700">
        <property type="entry name" value="Lys/Orn_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42802:SF1">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42802">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13434">
        <property type="entry name" value="Lys_Orn_oxgnase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8084209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="492" mass="53655" checksum="F628F4FD98570C98" modified="2025-10-08" version="1">MSPNTLVGSHIDGPPVANGQASAPMAGTASQPLPAMSSNLQATSADEVHDLICVGFGPASLAVAVAIHDGLESGAIQKSQAPKVLFLEKQQRFAWHAGMLLPGAKMQISFIKDMATLRDPRSHFTFLNFVHEKRRLIDFINLNTFLPARVEYEEYLRWCADHFRHVVQYGREVHSVTPVRSSSGGGGPVSVFEVTSVNAQTGHATAYRAKNVIMAYAHLVPKILRQSGAPYRVAVIGGGQSGAEIFNNIQKLYPNSKTHLIMRSEFLKPSDDSPFVNSIFNPSFIDDLYPRSASSRSALLQDARGTNYGVVRLELIEALYEHMYEQRREFGPDERAWPHRIHGATEVTGLDGKSNNSDGPLRLRVRSLRDHANASVASGEEAVLDVDLVIAATGYQRTSHLKMMEKVAPLLPGHHQPGDKLTDRDVKVGRDYGVEFAPGKVAKGSGIWLQGCNEKTHGLSDTLLSVLATRSGEIVESIFGDGSKGDMVKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLB1</accession>
    <name>A0ABR1WLB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005595</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668833.1">
        <property type="nucleotide sequence ID" value="XM_066809910.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042970"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018305">
        <property type="entry name" value="Ribosomal_m50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10501">
        <property type="entry name" value="Ribosomal_L50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="55"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="348" mass="36336" checksum="129DA4B5CB1B7B3F" modified="2025-10-08" version="1">MRRISRLGKPSGARLAPTARPLAPLCTPRAAAATRPSPTPAAAVTINTLRFYSSRQPEPLPASLTSGKSSAAPRERRRASGGARGPGARPPITTAASVRAAPAALGGGTGRYHHRHPVHARDHGRGARVDRRPGELVGRPGALARDERLCGVQAQAEGAGTGAPGGGGAPGAHGNARDEAAGPGGAADWDLGVDSDGTATVTGDLHAVADGLVVKEGESIVGSADILPSAAEALAWKQQADQSWKGTSLQDARLKFAVIKRVMQLTGQVVPDQKLANIATAREIETKKQDLVTLPNVAFSPKRVTRGHKDQALGRYKLIEAEFRKRDLQDGPLSVPKSREKKHWNGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM87</accession>
    <name>A0ABR1WM87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669152.1">
        <property type="nucleotide sequence ID" value="XM_066810229.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043289"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="153" mass="16941" checksum="50C2434804725F24" modified="2025-10-08" version="1">MMMPIPISRGDGGDAMTTKAEERQKNEQKNKKQKSVQVVALENDTEPAIYATSALNNSPSRLDLQSQPGKPANAKEGADDDQQLRKQGTTLETESKITAAIGTALVDPLSINQTLVTDKADDMDWHYVEEDCWMSPQPCCGDVFEMVDRRECH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMW7</accession>
    <name>A0ABR1WMW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006151</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669389.1">
        <property type="nucleotide sequence ID" value="XM_066810466.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043526"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF30">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="62"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="328" mass="36803" checksum="37263FB82578E3AA" modified="2025-10-08" version="1">MVPPLITLEEHFLSENADDVKQLYSEQLGSIPGVAEKLADIGPIRLKSMDENNIFMQVVSHGPGAMRVSQCQAANDQLAAAVRAHPDRFAGFAVLPMADPDAAAKELARCVREIQGFVGALIDNRSGNTYYDGPEYDGFWQAAQDLDVPIYLHPTWPTPEQTDLLYTGNFAKSATLSLSASGWGWHADVGLHILRLFAAGDVRPVSPRRRLKIIAGHMGEMLPFMLQRIMLLSPRWGARERPFREVYDTNLWITTSGVWSIDPMATILRNTKIERILYSVDYPFAKNEDGLRFMQDLEQSGLVTPEQLECIAYRNSEELLKLKVKSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNE0</accession>
    <name>A0ABR1WNE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fructosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669568.1">
        <property type="nucleotide sequence ID" value="XM_066810645.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043705"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="302" mass="34384" checksum="CF9844C3FCD0CA34" modified="2025-10-08" version="1">MHLWQRSEAEAPDVSKGLHGRESLKGEFESTAAIYAITPEFCPKPIAWGTLKSDPDSHFYICKFYDFVEDGLPGPKAFGSSLAKLHSSHTSPGGQFGFHVVTYNGDLPQDNTWSQSWEAFFLNGFQHVLRIREQRGGKCPELDDLLPDMFNKVIPRLLRPLETGGNHLKPSLVHGDLWCGNAAMVDEDTEEGIIFDPSSFWGHNEYELGNWRPERNKFCRKYFNAYHAHCPKSAPEEDYDDRNALYAVRFNLNAATLFPSQTIYLNIVIEEIKRLIARFPNGYEGNELQADIPKRPPQPHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNZ3</accession>
    <name>A0ABR1WNZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005471</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668709.1">
        <property type="nucleotide sequence ID" value="XM_066809786.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042846"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051458">
        <property type="entry name" value="Cyt/Met_Dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017149">
        <property type="entry name" value="GSH_degradosome_Dug2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270">
        <property type="entry name" value="BETA-ALA-HIS DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270:SF8">
        <property type="entry name" value="DI- AND TRIPEPTIDASE DUG2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037237">
        <property type="entry name" value="Peptidase_WD_repeats_DUG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="27"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="67"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="883" mass="98050" checksum="ABF6931FA0FDCF12" modified="2025-10-08" version="1">MPATTAPNASAPAVEVPPHTTPELNHVLKHDSSVLALVVGKDRIYAGTQDGEIVVWSLATFQPIHRIQAHKRSVMCLFLSDDESLLFSSASDPIVNVWCPSSMTRKYEIYSTWDSFGDIFSVSYSSQHQTVYYGAQNTTIQWVGLNDTSRVVAQDSTSHPDRRNHRFFDSRAVGGASTPRPTDERYDLIPRSHTVLETDRRAIRQYAHYGYVFCMLMARGVTAFADPEDDVLISGGGDGTIKVWQLGGNEVGPDGTLNGLREIMCLGEDNAESVMSLSIDGSFLYSGKLSGIVELWDLDTKQKLRVIKAHKGDVMALQMGWGYLWSAGSTGTASKHSTAHYGQYQVDCSQNVSQKYQLLTQWKAHAGKILACTVSNYEGREVFITGANDNTVAVWVVKNPPATEATEQQPSSPVVDEDMMISSLRDFVSFKTISSRPEYAEDCRRGATFLRTLFRKHGGDVEMLSADDNLHHPVVFAKFSGKLEPAEQRKRILFYGHYDVVPADSRKGNWSADPFQLKGTNGYLYGRGVSDNKGPIMAALYALTDLMQSKALDSDVVFLIEGEEESGSRGFQETVRQNKQKIGHIDYILLANSYWLNDITPCLTYGLRGVLHATVCVESKHPDLHSGVDGSYMVNEPLTDLTTLMSKLKGPRNRILLPGFYEGILPLTPEEEARFDDITTVLINQSPDENKSASDLKTSLMARWREPNLTIHRFKVSGPDGSLVSSHASSHISFRLVPGQELGDIIQSLKTYLRNEFDLLESDNELTVKIDNKAEPWLGDPDNAIFRTLEEAIMQAWVPLFDNGQGESQEPTPAVGGKLRKPLYIREGGSIPAIRFLEKEFEAPAAHLPCGQASDSAHLDNERLRVTNLLKSRDVFAHVFKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPA0</accession>
    <name>A0ABR1WPA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669843.1">
        <property type="nucleotide sequence ID" value="XM_066810920.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043980"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="706"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="751"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="777"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="796"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="806" mass="86489" checksum="A2000589BD5638B8" modified="2025-10-08" version="1">MPTAYAGKMRSNERPLAPCPRDPSPSSSGATMAAQSADWPLASENSDATLGPAALERPKTRRSYTSQAGHRTPVLLAGQALNSHPIPEFPFHRPVSAQGQVRGGPIIPGAHDSATAPFPGRSPAPSRSTAPSRAASPAASPARPPTRFGMKRSFNSMGSISSESASNDAPIGPPVRRETSTNRIMNGLATGFSRGAQVFSSAGSFFPFMSESPSKTRISAPYDFRHVASAEHGGGPMGGVDPGPDADPEATLSQTHRVLLDVRTDSRIHNRTSLPVAMPNVTSPIDESQFDAGCGHDSNRNSFNPFPSQTVTPATVQVHRPDQSPVAQRQHTCKMPSLAICHTIKALITSLGIALSVSILAVCITSFSTVSAITSMVLHSDENKVVSHQEAVWLTLSVGLCFTSMVAVAITYARRRTSRVATSHRNSQREEEMIELQNIIRHRISTPTRIRNSDPAIELDDMTQRRTSEAVAVGQNERALRLSGSITTPEPVHIRQSSRIVAQGLNNLAAPPNSIQSKRASGIFDAESVRTALCAQSVVEARRVAAAPIRTNGTPIGVARSDSLLRSIARRRGVDTRRDQQQEAAPSEDKDRAEDRNRSHSAESGNTVRTYESTNTETPMITVGLSREIKSSHSPQQSEHSKDVESLASSSDNLVSARIPHSVAVPDLSSETKLPAIPAVDTNSTLASLISSYADNGERAPTSQDAAGASYTTTYSAPRPQEALGSHPVPRAGRSNNPFRRLMELPRPPQQIVTESGTPDSQKSTERFPAYVDPGVTQDNDNTYTDTSGRRRRMTTIKERGEPMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPI3</accession>
    <name>A0ABR1WPI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006726</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669964.1">
        <property type="nucleotide sequence ID" value="XM_066811041.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044101"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="58"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="217" mass="24984" checksum="1DD9A7209DB631D1" modified="2025-10-08" version="1">MANSESAKMNKAEYWDERYQSADDPPPREWHLGYDQLEDYLKEHVYPHWPADANIMHPGAGSSHLPMEMHKRGGYTNITCAEFSPTVITQMQPLDPELKWLQSDVRDMSSVASGSYDVVFDKACFEAFCAWGPKHLLKEIPDVIVSDSRRYSQEMYRVLKPGGWFIIISVFEARYVHHLLKCEGTDWEDVHAPKALSADGWMQTRAFCLRKPDTQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPS7</accession>
    <name>A0ABR1WPS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_006810</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oligoribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670048.1">
        <property type="nucleotide sequence ID" value="XM_066811125.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044185"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06135">
        <property type="entry name" value="Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003765">
        <property type="entry name" value="PRK05359.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="OLIGORIBONUCLEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046:SF0">
        <property type="entry name" value="OLIGORIBONUCLEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="5">
        <location>
            <begin position="6"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8085539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="189" mass="21595" checksum="9467535651B03728" modified="2025-10-08" version="1">MSTNDALVWIDCEMTGLDPDKEEIIEIFCIITDGNLNVMDEAGWGTVIHQSKERMDMMDEWCTKTHEKTGLTAKVLASTVTPEQAADELLAYIQKHVPERRALLAGNSVHADRAFLRKEPYKKVTRHLHHRILDVSTLKEAAKRWCPREVNRNAPTKQGLHEARQDILESIEEARYYKDVIFQGKPGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPU1</accession>
    <name>A0ABR1WPU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006802</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670040.1">
        <property type="nucleotide sequence ID" value="XM_066811117.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044177"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045084194" description="Peptidase A1 domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="53"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="605" mass="63734" checksum="AEF3B31CF992266C" modified="2025-10-08" version="1">MPLPLPLLSYLWLVATPALVSATTNPVEAKWSPNAYGPDGPWPAVEVLVGGDQKIALYPGREFESFLLTTDYCTYNASVACQAAAAGLYSQMGSSTRTATGSDGGVQYLSPPNYMLGLPVKSHKNLSHWVDKVDFNEGSGAVPNVSMALLAESFATYPDGQWYPLTVGCLGLGAPETINQTFSSGSVSNASLIPGNLFERGRVESNSFGMHIGSAAAGSAKVSGALHFGGYDQNRVVGKILTSSGDYNRETTLKDIAIRVVDGSSPWSFGAAQEGLLTQGNSSMGSNGIYVHVDGCSPYLSLPKSTCDAIAKHLPVTYNEGLGLYTWNTDDAKYTQIVNSASALEFSFYGSSNTDRVPISVPFRHLNLTLDTPLVSSPRPYFPCFTGSDTYTLGRAFLQDAFVGANWGSKTWFMAQAPGPNVPPSNVVKFAGSDATSITASKNDWKESWSTAWTALTPDEAAGSTAVKPPNDPNGSNNNNQTDADSSGLSTGGKAGIGVGVGVGALGVIAACAFLWFRRRQRAKKGVTEGSNFNGNTNANGYNAMGSGAPIQGYYKPDSAVPYNPSAHDSTTYSSSDARYSSPNSQYPPHAYAASELPSDAYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQA3</accession>
    <name>A0ABR1WQA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670228.1">
        <property type="nucleotide sequence ID" value="XM_066811305.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044365"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="170" mass="18836" checksum="F22683ABD21FCA12" modified="2025-10-08" version="1">MPQGRGLKACLGPIVVRVCEFAAPSVFFNRPSPSSFSSFDGADSAPTQQGQAQMKEAPDRPRLALMQVLRLAVVPEHMGFEAAESSAARRREQRSDSPVDYRKHHGSGMAMPMVGIPHWSRLPFNDAHAASWRLDAKIIFNIWPGVAPMRSQHGSYHRSTNPVEAYWLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS15</accession>
    <name>A0ABR1WS15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acyl-CoA thioesterase II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007077</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670315.1">
        <property type="nucleotide sequence ID" value="XM_066811392.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044452"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03444">
        <property type="entry name" value="Thioesterase_II_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03445">
        <property type="entry name" value="Thioesterase_II_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049450">
        <property type="entry name" value="ACOT8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066:SF34">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20789">
        <property type="entry name" value="4HBT_3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="3">
        <location>
            <begin position="35"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase-like C-terminal" evidence="4">
        <location>
            <begin position="220"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="35763" checksum="BE49D48C006D7A1E" modified="2025-10-08" version="1">MPQLCPAEPVVAVTRLPATDVFINTHPFETPGEKARSVFGGYLLGQCVAAAQQTVPDTHDVHSLQSTFLLPGSPYEKVAYHVERISDGRSFSSRLVRAIQGGNVVHFTAIVGFQKRAPDDASANPPPKLSYHEAMPEFGHGNPDDIDQDSAEACLIEGGFPKDMLDTWRDPFQWRILPRDRTIGQTDTTSPNLDPTHFRMQSFVRVHPSMMSSPSPSSSSPSSRGTHLALLAFLSDLFLIYTTNLATARPVTAFSIETTMNHTVWFHAPEVPINDWLACERDTSWADDGRVLIRQRLWRRSDGRLVMSCVQEALARVQKPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWX5</accession>
    <name>A0ABR1WWX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DASH complex subunit SPC34</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Outer kinetochore protein SPC34</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PG997_002627</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex SPC34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670560.1">
        <property type="nucleotide sequence ID" value="XM_066806942.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040002"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013966">
        <property type="entry name" value="Spc34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08657">
        <property type="entry name" value="DASH_Spc34"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="206"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK8087666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="269" mass="29707" checksum="39089A8FC13F84B4" modified="2025-10-08" version="1">MSLLSAHFEQIAISCQGIDSLPFPPPKIFTNALLSNHDITSLIRDTEAHERALFSVPPPPPQPTQAKPATDQQPPPKQSSRRQTVFNVASGEVTTSGANHGRASSAAPRRHTAVAAVLGGDLHDQIRRSERGLWSKAAAANNGNQGVDVELLLKSAEKLCGVYPLPGALERIPAQRSKYAHSLNTLAYYEAKVAEQTEALGRQHKDMWSDEEEEEEEEEEEAGVADGAIMTEEELRREEEEVQELDRKKRELQERLKAMEKDLGGLMNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX26</accession>
    <name>A0ABR1WX26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_002676</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670609.1">
        <property type="nucleotide sequence ID" value="XM_066806991.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040051"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="9">
        <location>
            <begin position="4"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="10">
        <location>
            <begin position="895"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="2242"/>
            <end position="2319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="411"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="6">
        <location>
            <begin position="895"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1030"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2207"/>
            <end position="2230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2210"/>
            <end position="2219"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="6">
        <location>
            <position position="926"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="6">
        <location>
            <position position="1095"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8087715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2328" mass="250154" checksum="C3153D51BF0BC8E5" modified="2025-10-08" version="1">MPTIKPIAVVGIGCRLPGESSNTEALWEVLSQGKNCFSKVPEYRFNADAFYHQSDKTGTLTAVGGHFLAEDIAKFDASFFGISPSDAKAMDPQQRALLEVIYEGLENAGIPMESLAGSNTSCHVGCFTRDWSDMQIRDSEPSPKYTILGIGAAMLANRISWFYDWHGPSISLDTACSSSLVALDLACQALNNGDANVAVAAGVNLIFNPDLMMWLSNMSFLAKDGRSKSFDGGADGYGRGEGVAAVILKSLDRALQDGDCIRAVIRGTGTNQDGHTSGITLPSPEAQTNLIRSVYESAKLDFKETGYFEAHIGHTEGAAGLVGLIKAVLMLEKGLIPPSVNITNLSPRIPFDRLGVVVPRQLIPWPTEGLRRATVSSFGYGGTNAHVVVDDAASYLRLAALAGHHNTAHLWDGDSDGGGSSGSDSGIVDETFPSPAPSLPETSGFDFGLKPRPRLFVFSAHDEKSLAAIRQKYAAYLGSQKEMSASEPCFFDRLAFTLHARRSVLPWKTWTVATDMEDTPEAFASQAEPPVRSTSKPRIGFVFTGQGAQWAGMGQELLQYPVFRSSLTSADEYLRERLGCEWSVVEEIGRDAKTSRLHLAKFSQPLCTILQIALTELLGSWGVEATAVVGHSSGEIAAAVCTGALSREDGWEIAYWRGKLSSDLTTRNAALKGAMAAAGTSAEKALEYIKQVTNGTIQVACVNSPESVTLSGDEAAVDEVVDLLKADKLFVRKLKVENAYHSYHMSSIAEEYLASINGCLPSTPSKNIKLLSSVTGRSMDLAGLGPQYWVDNLTSTVVFSDALALLLKGEGRRRRRGETAVDLLVEVGPHAALQGPVKQVLAAEGCRNVAYTSILRRGKDAVASALETAGQLFTHGCSVDVMAVNQVSTNDKCDAPLVNLPTYPWNHGKSYWSESRLRKALRFRTHRRLDLLGAPASDFTRGDPAWKNHLRTSELPWIRDHKIQRTVCTTSGSSFAYPVAHTERELENNCSGFVSLQYQDSNGSDASSRETELEREVFEAAIAAEEAQCQEAMESVDFYARTESLGLQYGPSFRNLADIKSGPASACANVTIPDTASTIPYGYEDEHLIHPATLDCIFQLLYAALGGSSGQLEMAAIPFFIEKLKVATNCPREPGRALRGFARSQALGLVEYAADIAFGKLHGRSPPQIKISGIRCRRIGDCQDHAASATVQQRYGQFRIAPDLALASTADLERYLTPESSSQAEGAFAEAAVALAKILELVAHKDPYATILELGNDTRSALVPALLALSKSGLDLVKSAAFTVASNNKQHSEDEEHIVECRDDRRLNITHESMQSILADREANFKAVVLSADSDLSQLKTATALVGEHGFLLHTAHDWDAAEVTIGHCKSVGFAQTIIIPFPDNHHLVVASRTRSRDSAQMSDSITILLPDSPSETTLALANELALQFESQGLAIVKTHLRPDTLEQVSGSSCISLLELDDRFDLSEDPSRYDTVKNLYLNAKRLLWVSAGSSPHQGVIQGLSRTVKNENPHLDVAHLGLAAASLVDAHHSAVLVARLFLAGTEDREFVVDEGGVLKVSRYAADDAMNAYMLRMLDKNSAQTVPVGQIQTPLKLAIRSPGLLESMWFTADDRWQAQLEPDEIEIETRAIGTNFRDVLVLMGVLSDNLLGLEASGIVRRVGSAVTRFRPGDRVVTSSRGCYRTLHQTKEVMCQAIPEGVDFAEAASVPLVFMTALGALRDLAHLQPGETILIHAAAGGVGQAAIQLAQHYGATVLATVGSPAKAKKLQEAYGISPDHIFHSRDASFVGGVLRATGGRGVDVVLNSLSGELLRQTWHCVAPFGRFVEIGIKDIEENAGLDMAPFKKSTSFAFLNINLMLDEYHQKAGALLADVTQLFSQGVIKPVDSVSSYPVSSLPSAVATMQAGKHIGKVVITLSPQDELSVPTSVANRWQLKGEDATYLIIGGLGGLGRSLALHMSDCGAKNIAVLSRTGSSDPKAAPLRLELEKRGARVVFHGCDVADADQLESSLAKIAAELPPIAGCIHSAMLLRDGVFENMSHTDFRDSLRPKVHGSWNLHRLLPRDLDFFILLSSISGVTGNPGQANYAAGNAFMDQLAAFRRSWGLAATSLDLGLLLDVGFVAERDGVSNLKKWESVGLRDAEFRHLVTAATRGSIPAPGDDGAGGRKGETYALPAQVVCGLATGGHVAAHSLPEPFYFTDPRFAQPVQAELASSSQSTNGPAGADDAKKALRQSLGSSTSLAHAAGVVGEALQARLAAVMDSEPGNIDLRRPLHAYGVDSLMAVEMRNWVVHELQCDISLFDLLGSPNLADLAAKIAGVSRLVPAFESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXP5</accession>
    <name>A0ABR1WXP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Double-strand-break repair protein rad21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002899</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670832.1">
        <property type="nucleotide sequence ID" value="XM_066807214.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040274"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21788">
        <property type="entry name" value="Rad21_Rec8_M_SpRad21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="entry name" value="Structural maintenance of chromosome 1. Chain E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039781">
        <property type="entry name" value="Rad21/Rec8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006909">
        <property type="entry name" value="Rad21/Rec8_C_eu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006910">
        <property type="entry name" value="Rad21_Rec8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585:SF69">
        <property type="entry name" value="FI11703P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585">
        <property type="entry name" value="SCC1 / RAD21 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04824">
        <property type="entry name" value="Rad21_Rec8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04825">
        <property type="entry name" value="Rad21_Rec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Rad21/Rec8-like protein C-terminal eukaryotic" evidence="5">
        <location>
            <begin position="545"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="607"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="619"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="637" mass="69664" checksum="3463F73DF74E3A1E" modified="2025-10-08" version="1">MFYSETLLQKTGPLARVWLSANLERRLNKSSILQTNLQKNVEDIIDPNQAPMALRLSGHLLLGVVRIYSRKARYLLDDCNEALLKIKMAFRSTGNNDIPENLPLPNREALMLPDRITPADNLGILPPPNADWLLAQMDVEATQSSSQAQGRGRGRPSNQNINLQEDFNNSQFLEVDDMNIDDGPAIIDNDDLDLVLDFGDDDEQPRKDMSIEMGRDAPAARSIEDDVFSEADFGLQKGDASTAMDLGEGAIRIADDDGDIPMEGDFQFNIGDESAMPEVGGAGLPSRARISESPLSDIDENIARDVEEWTRINNTSIYEPGQETEIQEPQQQRKSAKKRKVFGLDAATQLTSAHIKEQQQDRSNILKAPSFIPRDPYFLALLEMKSTGSFVSNIMGDARSKPWAPELRGLLSLEAIRPANDLKRKRDSGIADMGEEEQGASKSPRLELEEDDGLAMPEGGFGEPSVGPEGTILEIPADDGMGIHDDDGARDESTMRAFDETIAPIVHPADSGPVSLGTKHAVHVLRELFGADAAESEEQRTKTSVVFQDLLPENRTTKADATKMFFECLVLATKDAIKVEQKEGVLGGPIRVRGKRGLWGAWAEREAGGEIASQEEEQATQPEPAIAGSSRAVAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXT9</accession>
    <name>A0ABR1WXT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670874.1">
        <property type="nucleotide sequence ID" value="XM_066807256.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040316"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF1">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="14486" checksum="975E36C3C1D87C4E" modified="2025-10-08" version="1">MSQQQFTSTGRGGAGNISDASNSPKIQPKDLETPTLKHTVVTTGRGGSGNMRTNKDPAETRALQDVEPVVERPKNDGIAHVGRGGAANVVKLGSPEIPEVKEVKEVKKAEGEDVKRTKSPDASLAAKGKEWLFGKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXU8</accession>
    <name>A0ABR1WXU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Pisatin demethylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670854.1">
        <property type="nucleotide sequence ID" value="XM_066807236.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040296"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF77">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8087960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="58770" checksum="F3A07895CFE4F715" modified="2025-10-08" version="1">MALLDLDLDKTGIALVALAALVLCYSVQAVVTWHRLRHIPGPFLASFSYLWLGKVTRSTRQWHIYRDLPKQYSSSLVRVGPNEISTDDPEIIRKVSAVRSPYGKDSWYDDCGYHVYMGSRFNPYEDTMFTTLDIAAHDKQKAKTASAYSGRDTTALEDGVDDHVKELVALIRRKYLNKEDKGSGGHQESNRLLDFSKIISFFTMDVITRAGFGQEFGYLKSDEDLHDFLRSVRENWSVIAVTLDVPWIRNVLYSNWFLRWFGPRTTDKAGMGKVMAVAEKLVGDRFRPDSKKQRDMLGAFMAHGLTQKECETEGLFMVVAGSDTTASVVRSTMLHLMSSPRIYNKLKREIRKAVDEGRASSPITFEEAKGISYLQAVIYEGLRIRAPAPGLYPKTVPPGGDWIHGKFIPEGTAIGMNAAALTRSKALFGDDADLFRPERFEEVDAAARTKLENLSELVFGYGRTMCAGKPIAFMELNKVYFELLRAFDFQLANPSKPWDSKSYAVWVEENMWVSVTETSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYF5</accession>
    <name>A0ABR1WYF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003143</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671076.1">
        <property type="nucleotide sequence ID" value="XM_066807458.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040518"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="302" mass="32208" checksum="616E519C0F9EC360" modified="2025-10-08" version="1">MNQKHRPRLRRPLRRRRLAEHLAPPHESDAAPPLVLARQLHGHGGAVRHRHRGVGSLQLHGGARRHHHRGPGGNTVGGVGGWVGGGGHSVVSSTLGLGADQVLSLDVVTADGRYVTADPFTNPDLFFALRGGGGATYGIIISAVYKAHPPITLTTTSLSLTLSSASSPSIPTNGAIVVRNADAFWTGVGLYYRFCGRIIEGDGGQGFSYIYPQADGGFRFTTTSTFLNRSRDEVGRIMQPLYTSLRQAGVLTAADADPTTRNSSIYGASRRGGTGTSPSTRGKSDCLRESSCQLWPRSRTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYI8</accession>
    <name>A0ABR1WYI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671118.1">
        <property type="nucleotide sequence ID" value="XM_066807500.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040560"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46283">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="407" mass="43993" checksum="358AFA81445695CA" modified="2025-10-08" version="1">MASSPSPISPAPGDATAFDDTASASRVQGEPIASEEAAPAPQIPDNREISNAEPAATPSPAQDEPNDQCMLTWVADLEGQGKDIKCPICQSPIQVLDKWDPAVQFSDEIMRTLSNMSPFVLLSFLCGGALVSSAFYGMHALEIFAGSDAVHGFVFTTRAKDTGYWSMAMDKVKNALPALIPQEEDATRAIRNGRSQEDSVNVLHFLSLTMVGPALILNRLYLGNFVIVPTSVVYAMFFVEHQSDLLAWPPGPRKAMAIFPTIKTLYLQAYWACAKMVDRRVEAALARNRSLQGETARPVAAPQPYNPHVAPEDDEADLIDLAIAEEEEEEAGEPQHGPAEAQAQADRRANPNSSLSSVLNFFAGALLWPTVSYSVGNLLRMTLPKSWVTRPSKGPITEELSTDPIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ13</accession>
    <name>A0ABR1WZ13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003352</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bZIP family. Jun subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671285.1">
        <property type="nucleotide sequence ID" value="XM_066807667.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040727"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050946">
        <property type="entry name" value="AP-1_TF_bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002112">
        <property type="entry name" value="Leuzip_Jun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462">
        <property type="entry name" value="JUN TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00043">
        <property type="entry name" value="LEUZIPPRJUN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="128"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="60"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="204" mass="22649" checksum="C5D8E46F35FFA79E" modified="2025-10-08" version="1">MEFCPHPSDHHMAYEIPQSPMGTSCDPFLDPCITNAYQHDPQHFFDLSADHQDAMIKLEDIGQPQPWESFSSTSESGVSEMMEPMAPTPSRRESAATQPSAAAAAAAKKPRRDRARSGSSGGSTDLSREKNRIAASKCRRKKKDEERILEDRRRMLQVQNAILVDSATSLRAEVLQLKHEILRHGTCDFQPINSYIATAAARVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0E2</accession>
    <name>A0ABR1X0E2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671713.1">
        <property type="nucleotide sequence ID" value="XM_066808095.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041155"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="361" mass="38114" checksum="9FAC2EB663B33B8E" modified="2025-10-08" version="1">MSEKAEVSRHDTPNGSVSGAGIVGPKSKGAKGHCKKFWWIYVLLLVVTVVIVVPCVILVAVPNMAQSRLDNASLDIDSIVISQAEKDSFHMAINSTILADNGVHATIRAFEGTMSLLPDNNDGAAPMAFAKFQFPEVASAASVVVNVSQKVAVEDVDSLVAFNEALLAKESVRVRVEGDTQIRVAGIARDYPVTFRKEVELKAFNGFAGLSVSNINVTLASANNFNGTVHIPNPTVFTFELTNAVSCNKKGNTTWNNYLDGGANVGTAYIQDLAMHPGSNDFFIWADIAQGPVLTALGKKPVCESPDGDLTFQLSGKAVENEGQSIPWLATALSAHNASATMPVGAAVAKALGGRIPCSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0J7</accession>
    <name>A0ABR1X0J7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003846</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the E3 ubiquitin-protein ligase UBR1-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671779.1">
        <property type="nucleotide sequence ID" value="XM_066808161.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041221"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16482">
        <property type="entry name" value="RING-H2_UBR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2670">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042065">
        <property type="entry name" value="E3_ELL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044046">
        <property type="entry name" value="E3_ligase_UBR-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039164">
        <property type="entry name" value="UBR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055194">
        <property type="entry name" value="UBR1-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497:SF24">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497">
        <property type="entry name" value="UBIQUITIN LIGASE E3 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18995">
        <property type="entry name" value="PRT6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22960">
        <property type="entry name" value="WHD_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Adaptor protein ClpS core" evidence="4">
        <location>
            <begin position="254"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="E3 ubiquitin-protein ligase UBR1-like winged-helix" evidence="6">
        <location>
            <begin position="1058"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="domain" description="E3 ubiquitin-protein ligase UBR-like C-terminal" evidence="5">
        <location>
            <begin position="1660"/>
            <end position="2151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="439"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="504"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1631"/>
            <end position="1650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="441"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="508"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1631"/>
            <end position="1647"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2175" mass="244915" checksum="8578182FD008B13A" modified="2025-10-08" version="1" fragment="single">NTVDFDFEIHKLPTSHATDQVPSLAMDTANMSTQELQLCQHLIELPQRHGYRYTDAASRDLLSNLFWSMAGGKPEYMRLLFPDGKLPSTGGLKLSEAQGAIEGAEYTEAARGKACGHIFPRRRGHLLVQDLRCRRNMLPLQQITGATWFASAYRPETVVAVTAGTPRPGSDRYTVQSTPNAKARPRGRAKRQQACPSPLLNNIRMTIARAIDFICDVVSCSPEQLRQPKTKTSIEQDEKMSRLNSTYCGGDIESPGEFSVILWNDEKHTVVEVQEQVARACRMSSADGYQRAHETDNMGRSILMYHRDISHLLDVARILEQIKVTVTIRSSRDTFREQMCGSMVSWLNDIAGCSVGGDGSILRQIVCEELLMPWRKGSPAIHASLTNISIEDEEKIEYQHYQRETARLFVTRARMMAFADATGTLPAGITAMPRNLAALLDDSDDDDDDGQTPPSAEEDNDNSDDEDDGDVMMIDAGAGAAGDVNMSDWRQGPIGEALEEEEATIAGYPPPPPPPPVPRRNARDRDLTPSDSDTAEPLIAPTVYAKVNLEVPKTPGHAKADKVDPPRPGRYWVETPAAYLENADSRPYEDGSPGLVDLVRLAAVEKVRNDLRALYISTVVTIPEFKRILGLRFAALYTTLAQLYLIGDREPDHSIINISLQMLTAPSITAEVVERGNFLTTLMAILYTFLTTRQVGHPWDVSSSAVLGFDTGSVTNRRMYHFYVDMRYLFSSPHVQERMRTEERYLLQFLDLVKLHQGICPNVRAVGEHVEYETDSWIGASLMTREMNQLCRMLADSFRRVPDHDLQCIPRAIRLTAKSVVVNSIGAERARFTQAEVKDEIRFKTLTDFEFAGESTKFDVVKFIVEEQPISFHHALHYTLSWLIECGKDMSAQELASVLSFTSQELKMKPKTMGRKTLPRREYGPEDYLMAAFDYPLRVCVWLAQIKAGMWVRNGISLRHQAITYRNILHRNVTHHRDIFLLQTALVICDPSRVLASIVDRFGMDNWAKGFFEQCSSAQDETQHLDVIEDMIHLLIVLLSDRTSLITQDEREMHLMAMRRDISHVLCFKPLSFNEVCTKLPDKFHEQEDFQQVLDEVATFKAPEGVSDNGTFELKPQYIENIDPYIAHYNKNQREESEAAYRNWISKKSNKPVEDVVYEPHLQPIESGAFIKLAAFTSTGMFAQIVYYSLLYPLVATKFTPKVPYTRVETFVQVVLHLVLIAISEDKTAEHNGPTEESFVYRALTSQGRSNFMPEAPAAKTIVSLLELMSAKEELKACHPKINLILKRMRQKLPVHFDTAYTRLGIPIDRIDTASPASAHFAEEEREKKKKAALDRQAKVMAQFQQQQKSFLELQGDIDWGDEDLDDMGDEQTVEERKNFWKYPRGTCILCQEDTDDGRLYGTFGLFMESHILRQTDFQDADFVREAAQTPENLDRSAEDIRPFGLAHENRVAIEKINAAGETFVTEKQGLGKGVPAKLSRPGPVAVSCGHIMHFSCFEMYTEATTRRHVHQIARHHPESLERLEFVCPLCKALGNAFLPVSWDGKEESYPGALQSQDGFASFLDYHMGIISHMGPRLRGSLQHAFADYVRSAMPDSLVEGSTQLVMDSWNVSRPPSVSVSTPFSDAFSSVATPESSVRSGSPSDAQNSDKELMSAYRRLRDTLRNNKLYAGPDGEDKDDELVGGGAMARTVGYSISATEIQQRGLEAQYGMTLIEKIPEQALIQLRILSETTSSYISIGGLRNGGDNRMEADFRKDSERQHCQLFISEYFGRDSSSSRHPAKDYPPLLSQDPFIFMCECVFGVAAAHNIDITDLVRLCYFAEIVKVVYNISRNIPIGKWLEHLGNRSTEDTALNNFANFCHAVTLAGINSNCEDPELSDDLPNMGFDQPSFESLSNFYVFVQRYALVFLRKTAILLHVHFGVDLNSYIPTAPELDELSRLTAAMRLPSFDEMCTALTPLGANYGWPKQMERLAQGWIKHQIAFRPHLPIDNSLEAPHRLPSSAQVSHPGIFELIGLPKNFDTLIEECARRRCPKTGRDLADPIVCLMCGDIFCGQTMCCIMDYKEPGPGDKPSKKIGGAQQHMLFKCQRNMGIFINIRKCAIFYLHRKSGSFSNAPYIDKYGEVDVGLRHGRQLFLNQRRYDSMIRAMWLGHGVPSFISRKLEADINNGGWETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0K5</accession>
    <name>A0ABR1X0K5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphotransferase</fullName>
            <ecNumber evidence="11">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_003919</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:16126"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a D-hexose + ATP = a D-hexose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22740"/>
            <dbReference type="ChEBI" id="CHEBI:4194"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:229467"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:22741"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671852.1">
        <property type="nucleotide sequence ID" value="XM_066808234.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041294"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019807">
        <property type="entry name" value="Hexokinase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF16">
        <property type="entry name" value="HEXOKINASE TYPE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00378">
        <property type="entry name" value="HEXOKINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="12">
        <location>
            <begin position="16"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="13">
        <location>
            <begin position="218"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8088958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="482" mass="53055" checksum="1F0408E642FBF931" modified="2025-10-08" version="1">MPTGSMADVPKDLLQEIKKLEEQFTVNSVTLKKITDHFVSELTKGLSVEGGSIPMNPTWVMAFPDGHETGTYLALDMGGTNLRVCEITLTNNKSEFDIIQSKYRMPEELKTGESDELWEYMADCVQQFIDTHHGGAPPATKIPLGFTFSYPATQNYIDEGILQRWTKGFDISGVEGENVVPMFEAALNARGVPVKLSALINDTTGTMIASAYTDPKMKIGCIFGTGCNAAYMEDCGSIPKLAHMSLPADTPMAINCEWGAFDNEHKVLPRTPYDIIIDKESPRPGQQAFEKMIAGLYLGEVFRLVMVELHDNKEVHIFEGQDISKLRKAYTLDASFLSAIEDDPFENLQETADLFNDKLNIKTTRPELELIRRTAELIGTRAARLSACGVAAICKKKNMTSCHVGADGSVFNKYPHFKARGAQALREILDWPAKANHKEEDPIEILAAEDGSGVGAALIAALTLKRVEAGNMSGILHPENFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0L8</accession>
    <name>A0ABR1X0L8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003880</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671813.1">
        <property type="nucleotide sequence ID" value="XM_066808195.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041255"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="659"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="263"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="429"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="472"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="849"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="270"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="483"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="531"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="870" mass="95849" checksum="D9B66ABB859ADA8B" modified="2025-10-08" version="1">MDRVQDPDRLAPPAVSSLRRAEAAGSAMERTLSEGIREEREELREAAEQTLNVIVDLNLDGTIRWTRSEGTPIADLIIGDDKGVFADAIAYMKQDDSRSHFIRFTVYLGPLSKLITVNELGEPENSENEPATVELEAQGIMVYDRATGGESHTMWMIRPWIAPREVKIDLPPLIRSLGTMILKTTHHRCLSSVVFASAKFHHGGSKNIPIFCLQEHRAEMDVQMAQENLVEHRHSIVKVLDALEARKARPLSGEQQATLPVAEYKGLSIGPTSTTSSPGTSSPAASSRDRSGTIGHHRSRSFAVRRPQARIVELLLDLCDTSIEVSTPAIKESGSQGSGEFRTQSPQSESRISQVLQWQSPGSNTLEQEQGLALLCADTERVAKEKVEAVFRYRRILEYTERIRVEFAVLVQDCIDEAMRKAARIAAGRLSDSTEGEDLSEESEVTPAATEEPIFPGSFEAPSSLVLALKNTDLGEPGDRPRPSSIIGSTRSSSPRECSTPRSLRGGLSVAGQTRESRRESLMFESDAGESEGSVRSSSVMSRPPRTDSPISEFGGLRRATSSRQQQRRSLIIPGASSPHRQESPSRNAPPSSPLRILKPRSFQHSQDSIVSPEASPMLPHSEFGSPASVPHHHRRQSSAAFPEFINRHPPSPRLNPANAAPRLVRKGAFGSVYLSKKKSTGEYFAIKVLKKADMVAKNQVTNVKAERAIMMWQGESEFVAKLYWTFSSKDYLYLVMEYLNGGDCASLIKVLGGLPEDWVKKYLGEVILGVEHLHDRGIIHRDLKPDNLLIDQKGHLKLTDFGLSRMGLIGRQKRALNCSNPEQTPDLLKSGPFARSTSIASSRSASMDLYAPHHSPGTTPQMTPFRYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X100</accession>
    <name>A0ABR1X100_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HhH-GPD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004068</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672001.1">
        <property type="nucleotide sequence ID" value="XM_066808383.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041443"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045138">
        <property type="entry name" value="MeCP2/MBD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074:SF0">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN PROTEIN 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074">
        <property type="entry name" value="METHYL-CPG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="4">
        <location>
            <begin position="304"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="514" mass="56951" checksum="98A9BC1A23FF2919" modified="2025-10-08" version="1">MQTQKVPTAKTSSRMLQGFLEIPPQETVSLGQAGSKPIQHKASTIPSDSKNSKRKRSQDSPYFAEHDIPESVAKKVSKRARKQARRQARGSAFAEQLEPNDASCAAQDNATVLQDAASWYLGNRNDKHKGAAQDEGDDAQNENCGKPHSANRTVEDHDGLEDQPDTIRDEPMSDYEIQSREFDAAVDSQSPLAETYDVNGGESTESASLQPTLAGRKRPSDVEELARRVLRSSTCTPKRTNSSKFFESIPKASSPTKAKSLRPPKGTVSALPFPTLSAPRFGLVQEELAGDPFRLLIAVTFLVKTSGKAAIPVFRRLMDKFPGPGALAEARASEISAMIKHLGLSVVRTAQIQKFARIWLEKAPAKGVRYGVKNYPRAGDGSEIRAGEEVSAEEHDDSRTSAWEIGHMTQGPYAIDSWRIFCRDVLLGRAQDWKGKGREGEFQPEWMRVLPQDKELRAYLRWMWMLEGWAWDPATGDKEVLSEQLRSAVNEGRVAWDNTGNLTIMEKQEGDAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1Z3</accession>
    <name>A0ABR1X1Z3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Meiotically up-regulated gene 190 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_004399</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672332.1">
        <property type="nucleotide sequence ID" value="XM_066808714.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041774"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04041">
        <property type="entry name" value="C2A_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21676">
        <property type="entry name" value="SMP_Mug190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057349">
        <property type="entry name" value="C2_Mug190_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037767">
        <property type="entry name" value="C2A_Mug190-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348:SF2">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25331">
        <property type="entry name" value="C2_Mug190_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="356"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="631"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="838"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="201"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="429"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="821"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1165"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="821"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="869"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1182"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1200"/>
            <end position="1209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8089438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1348" mass="150159" checksum="928E628C4C583411" modified="2025-10-08" version="1">MSQSDQFNEEDETQRQFAHPRAGKKHIPTISKYRAERRELEGQMRETEVAQEGPEDDSRPKRAYDSVKAIFKEEDEAAKTDHDPYPVANHHYQGNEAERGDKAGGDGDMSDVDADDEQDPSQNQPNSSQQQQQQQRQEQYQGQRGGNGGENQEQEQTATEAVVSTLNPKEKRKAMKKTKRHGGGREVTDPVTHLPIVIHDQTDKDMKHVPENEAEPGSDYDTATGLQGASKSDEHLDEEEARLQRGFNGMQRLFPPPDFADLRGEMATVYQQAVRAGLGSLGFFAAVFFLVPSFWGRFHPSINAAIALAGFLGTAGIVVVGMGRWISKKANEIFDDEVWDASKREENARLDSDTELPESVQWLNRLIASIWPIVNPDLFSSLIDQIEDIMQASLPKVVKMVSVDDMGQGNEGIRILGVRWLPSGAASMTLNRDGGLEKPDNSKTGSSDSTDTEDENGEEGGQKQQGTDESEDNPQDDRIKTGDEQGESPEERAGMEAEEGDFINLELALSYRSRSSGKGIKAKAKNAHLYLKFYLPGVYLSQFGLNCEGSLRSCGLGYSLHLANDLVKPDPPFVSLCTMTFLGQPRARISCVPISKHSVNMLDVPLISSFVQSAIDAAMAEYVAPKSLTLNLKDMLVGTDYKKNTISHGVVWIFIKQARGFKQGDGGFGPFEGSSDSYVSVSWGKFGKPVASTRIIEKSQEPNWHEYASILVSPEELNAEEKLRLGLWDSDKMSADDDLGRVELDLKSLIHDERTHNKIMDREDRFHGQDSSEKMAGSLAWSVGYFTKAKITEKQLEQQTINTEIKNRDQLKEHVAKTAEEKLREANKTPDDEEVMQQKAQDMAELEDEMICSAPPATSLSRDKGGGEDREDEAEQDNDMPDSYCNIIMNHRKIYRTRTKPKNSKPFFNAGTEKFVRDWKNTEVIIAVRDAREREADPLIGIVYLPLEKLLAKRSQVMETYPLVGGVGYGRARISVVWRSVGLHLPPHLRGWDYGTIELKGTAKAKSGLPDSLKGHRIKFRTNMGRCKMYTNNNGPSGEWVQKNNIDSQFLPVRKRYSSPLIMEFRQSSFGPDRTPAFGVLWLQGITEEEDETHTVKVWKGGKEAQARAESCCAYSGMEDGEQPLGEIEISLKLWRGLSGYHKSYAAKAKSDDMRSVMECLDTVTDQSLDDDSDDGLISSDSDSDDSDDSDDSDGSDDGNDAKKVDSQTKKKLKMHTNDDSSVDSSDSGSDSDGDDGKRHGKSNSVLSLSGFKKAKNILKNPIDGTVDTATSVMAPGHVDANDSSRGLRNQMRDYKDHKNQLHRKHRGIMQWRVAREFDYLGSKLSKLSNVSRIFHHGEKETGIETEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2G2</accession>
    <name>A0ABR1X2G2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004559</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672492.1">
        <property type="nucleotide sequence ID" value="XM_066808874.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041934"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12241">
        <property type="entry name" value="RRM_SF3B14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034150">
        <property type="entry name" value="SF3B6_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="13"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="107"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="209" mass="23337" checksum="40B5666A5AD12CDB" modified="2025-10-08" version="1">MSRAGKLAPEVNRALFVKNLSYNVTPEDLFELFGKFGPIRQVRQGIATNTKGTAFVVYEDVMDAKQACDKLNGFNFQNRYLVVLYHQPEKMVKSKEDLEARKENLAQLKKQHDGSVDKLQTPRSHRTSAVPSLSPTSTYTSSSVPSLKKTRTPRTPPSPVKKPAKSTMATATPVIRKNRADDSAEQARSTLMGFVRGFLPRNSNKMCMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2S4</accession>
    <name>A0ABR1X2S4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004682</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672615.1">
        <property type="nucleotide sequence ID" value="XM_066808997.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042057"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.400.10">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF261">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="28"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="675" mass="73210" checksum="4AC323DC2503310A" modified="2025-10-08" version="1">MASNGTTAPVVDATKSNPLVHDYPEPLKIAVVGAGIGGLSAAIALRRQGHIVDLYEQSSLASETGAAVHLAPNSNGLLRRWGIYAEKFGACNTTKVVEFAYTGGVIKEVDLTMPNKMWQHPWQLVHRVALHDNLKAVATAKDAPGPPATLYTSSKVTGVDPDASTLTFADGSTRTADLIIGADGIYSKTRKALGGPETRLFGSGKAAFRFLLPRQVALDDPVTRPLVDRVDSLCMWFSDDRRVVMYPCNNNDTLNFVLIHPADLSHASPSDEWNKQGSLEQVLKVYKDFDPALKQLISKVSPEELKVWQLLDMDKLPSWVRGSVALLGDAAHPFTPHQGQGAGQAMEDAAALAVVLPKGTAPKDVPERLRLYEKIRYDRAHNIQEYSRQSGKDWVNGVPQIDVMKYTAYNFGHDEFDNSTRVFNEWLSSQKPDLYRRMPVGFGPAPGPRQDVYGRPRSGLDQSRFVNTTVKFETSRTYLESLFPTPAFRFLSPATVCLASVAVTTLDGMAWLGGGGYSHCGLYLHGNLADAVITGRDELGFNKTFCDIDIDRSSGNNATSYNARCSWRGAKFMEIALDDLHQGGSGSTGQPGKADVEYACVAPAAEEAKAAARTVESRATAGKASLKFDAGSWQTLPTLHHVASVLAGIPVYRVVEATVVEGTGVPDVSSCRRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X379</accession>
    <name>A0ABR1X379_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672739.1">
        <property type="nucleotide sequence ID" value="XM_066809121.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042181"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="116" mass="13395" checksum="795A67C60E6806A7" modified="2025-10-08" version="1">MARSRKVSSPLGAATPALRYPLDSLPPVKLDRLTKWEHMQIRKIRKQRRAHRRRGLDRKLAHINFTTDNIMQDSEDDDSISEDEGEEEHTPYDSSDECGGFYPHCCCYAFIGDLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X398</accession>
    <name>A0ABR1X398_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_004854</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672787.1">
        <property type="nucleotide sequence ID" value="XM_066809169.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042229"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17963">
        <property type="entry name" value="DEADc_DDX19_DDX25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="11">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="100"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="297"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="7">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8089893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="472" mass="51558" checksum="C33945CBF60BF2CC" modified="2025-10-08" version="1">MSDLASRITAPEASAAPNLDMGDVETAQTDGAGMIGNGSGLQEVNYDVEVSLNELQRDRSNPLGSAHTFEELGLPGEVLQGLMAMQFQKPSKVQEKALPLMLANPPQNMIAQSQSGTGKTAAFVTTTLSRVDFSQPTQPQALILAPSRELARQIQGVVQTIGQFCASLVVAAAVPGAVARDTRIEASVVCGTPGTVMDLIRRRQFDVSQLKVLVIDEADNMLDQQGLGDQCARVKQMLPPTVQILLFSATFPDGVVKYAEKFAPNANQIKLKVQELTVRGISQMFMDCPDESQKYAILCQLYGLMQIGSSIIFVKTRESANEIMKRMVADGHKVTALHGAFEGGERDALIDEFRSGRTKVLITTNVLARGIDVSSVSMVINYDVPMKGPGEREPDPETYLHRIGRTGRFGRVGVSITFIYDKKSFDFLQQIAEKYQIDLIRLVPDDWDTTEKEVQRVIKSSRAQSGFNPSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3P5</accession>
    <name>A0ABR1X3P5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA sliding clamp PCNA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004996</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PCNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672929.1">
        <property type="nucleotide sequence ID" value="XM_066809311.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042371"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.150.10">
        <property type="entry name" value="DNA Polymerase III, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022659">
        <property type="entry name" value="Pr_cel_nuc_antig_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00293">
        <property type="entry name" value="PCNA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA N-terminal" evidence="5">
        <location>
            <begin position="12"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA C-terminal" evidence="6">
        <location>
            <begin position="97"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8090035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="232" mass="25750" checksum="208E53C7A60B9BE2" modified="2025-10-08" version="1">MTLALRCRPWTTPHVALVSMMFKADAFSPYRCDRNIALGVNLVSLTKVLRAAQNDDVLTLKAEDAPDSLNLLLESVEADRISEYDLKLMDIDQEHLGIPETEYAATIQMPSAEFKRICTDLMAMSESVTIEANKDGIKFAANGDIGNGSVTLRSHSNVDKPAQNVDIELTEPVTLTFSLKYLVNFCKAQPLSERVRISLSSEVPLLVEYLLSNDKNSGHLRFYLAPKIGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X414</accession>
    <name>A0ABR1X414_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673036.1">
        <property type="nucleotide sequence ID" value="XM_066809418.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042478"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="175" mass="18765" checksum="17F9C4463A433F90" modified="2025-10-08" version="1">MRFSPSPSKRRSQFLLGVSSFSSPIRGGRAGILSSSANPSTPSQQRLPPSYASSQCLPSVDTMESLESASTSSASVDDSYSADHKDSENIKAQQEQQSKLVNQEEKNIKMQQQQTFATPYNSTNTRGRPNGNRGHARLLSELSATLRLVHEEEDAVAEQATASASSTRTAAGVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X435</accession>
    <name>A0ABR1X435_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005107</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673040.1">
        <property type="nucleotide sequence ID" value="XM_066809422.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042482"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="35706" checksum="D33C53CE2B54B529" modified="2025-10-08" version="1">MTVVRPPTYRGSRYFGNQPLVEGPSFLMTMPNEILLRCVEMIMEEDEDMNDMTTSKALLGLCLANKRLCGLAQRFLYARMEIHVLDMKPGRRLRRQSKEVLEIIKRRALRLERTFRSNPALTSLVTSLTIDLDWTSRPPFGNAISLAKRFPNMRCLELCGVYSVTSWELIDYENQFKVNVDDENFRISETDEEPLSTPLHIRAFEKGNPHTLRSFLTWPAQLEVFTVDELAVADFSWEMLLDDLHANLCVWNYPLLSSVLQPSKKTLRHLAIGQMGRQDGFDEFDVHDFGALETLAIAFLASPARQTRAGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4J6</accession>
    <name>A0ABR1X4J6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005288</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673221.1">
        <property type="nucleotide sequence ID" value="XM_066809603.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042663"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="267"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8090327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="403" mass="43994" checksum="1B214889F4388FDD" modified="2025-10-08" version="1">MYIRDILASSSGGEGGGTTSNGDVTVTESTTNTNTNTNKRLDGHQLLVLTDVSRFPELQPGSVWRRRVEQAHPGLRIVVHDQDTWRDRTFPQDLDWAHTTLLLSGAVFPSPDVAPRLEYIQLQSAGADPINQTPIFKETEVAVCTTNGVHGPQIAEWVIGTFLALNHQPSVSIIIIMESPLPFLQRLTSKHRGILGYGSIGRQVARIAKSLAMDVVAYTNHPRPTPESRRDNGYIVPGTGDPDGEFPSAWYSGTDDADIDAFLGSGLDWLVIAVPLTESTRGLISEARLKLLSSVKDSQTPQGQVVVKPFVTNIARGPILDTDALMKALDAGWIRGAAVDVTDPEPLPEGHPLWSKKNLIITPHISAMSNSLGHRIADVLELNLQRFSEGRKLVNQVSRKEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X514</accession>
    <name>A0ABR1X514_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673386.1">
        <property type="nucleotide sequence ID" value="XM_066809768.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042828"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="360" mass="39960" checksum="54D3AE8D9B6A59FB" modified="2025-10-08" version="1">MGTSQPDVVTIVSLRDRPDLWPQFIDEEHPINKMMKAQQPMNDLSHSAHLACFDNLGNFDEFRQYLLAAVRRTADGGEEMVGRAQAVPFHWPDLQGAQPWQHDTVALACKGLPDGGFLTVLAIAANQAVSRRASSGRTAPANLGVDAGSPSTADEHVHWTTAQLSEPPNLLSALEVAVLPEWRRPADLAVRLIRALRQAADDSGFPALVVPVRPTRKLEHAQVSIDEYISWSLPGNPALPYDPWLRKHVREGAQIVKTAPASEVFQGDAQQWSHYTQQDISGLVREAVQAAPGALVVDVYFRGGMSPIRWDVEKSWGVYAEPNVGFVMILSMMVLNSRQPAKPQPWVNYETIRWKRDWSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7J7</accession>
    <name>A0ABR1X7J7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001817</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673428.1">
        <property type="nucleotide sequence ID" value="XM_066806132.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039192"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="9"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="310" mass="33281" checksum="7515C3378DD6A859" modified="2025-10-08" version="1">MPSFTVFKGQKDGIPRQSTTTKPDELTSDNVYVRITASGKGQDMVLGHEGIGVVESTGPDVKYLKAGDRVGWGCLTGHETYCAEAALYGSSNPDQGSFATNAVWREAFLHRIPDDMSDEVAAPLQCGGATTFTALQGIKSTDTVGIMGVGGLGHLAIQFAARMGCRVVVFSGSEAKKAQALALGADEFVATKGATSLSVSRPVNRLLVTTSAQPQWDLILPVMAPRSAIYPLSVSSGNFEIPYMPLIEHGINVQGSLVAPRHLHREMLDFAARHRIEPIVEKFPMNEEGIKTALDKLEKGDVHYRAVLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X836</accession>
    <name>A0ABR1X836_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001978</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673589.1">
        <property type="nucleotide sequence ID" value="XM_066806293.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039353"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="312"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="347"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="540"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="581"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8091617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="591" mass="65920" checksum="7C710211448FCE6E" modified="2025-10-08" version="1">MDMDIEKRPGEMSGVETGSKTLPCDIFWTLAHTFLQNPVDVFNLARTCHGNWELLETEIFRTDVVFYKTILGSSREEPGNVTMADDSASGDTTPEGSVHEDSAFEDSDEDLEDTMDSGDYDGRAYVPPKKRERNFLHCLADPKWRPPTILQWAASSGHEEVAETSIIVAGRVWPEYVFLEHPDSLNSALHFAAWYGNLGVLRLLSQVRINDRLLNMNTLAGVTFNAESNAKSYSNRTDHGLCDVFQGINPSIGYFPKGPFTVSDRRDTFGINAAGLAILRGHTSAAEYLIDNFYGNDITEYGEPRTATGLRTPVDPLHLACFMGMENIVATILEKGADVNSHAHQMEDSTPLMLAVARPNNDRIINCLLSHGADVNIQNIWRRDALVWAILFQSHENALRVVKAGARVDFRFRRLRGYLNDEYTQILCVEDDAFLPCTKLILQRYPDLPAELLRACVNHAFKNLKKNQATVRWLVDQGLGLGPLERTDYPFRGLMAYPGVVEVGFSALHHIAGSEALPLELLSMALDKRPEDINVIAGETRHTPLSLAFKFGYDSETVALLLAHGADPAATKSYHKRNPRTMINDQPKVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8W5</accession>
    <name>A0ABR1X8W5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673792.1">
        <property type="nucleotide sequence ID" value="XM_066806496.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039556"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.580">
        <property type="entry name" value="Acetamidase/Formamidase-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004304">
        <property type="entry name" value="FmdA_AmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054833">
        <property type="entry name" value="FormamaseFmdA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF045496">
        <property type="entry name" value="FormamaseFmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891:SF1">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03069">
        <property type="entry name" value="FmdA_AmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141130">
        <property type="entry name" value="Acetamidase/Formamidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="455" mass="48764" checksum="57D8C9587A5DC8B3" modified="2025-10-08" version="1">MGKTAIRTAAKVSFDIPASEQKVLHNRWHPDIPSVETIKDGETVKIECVDWTGGQIDNNDSADDVRDVDLTKIHYLTGPFDVEGAAPGDLLLVEIMDVQPFEDQPWGFTGVFAKDNGGGFLDEIYPSAAKAIWDFEGIYATSRHIPHVKFAGLIHPGILGCAPSADVLSTWNAREGELIAANKLERDVAKPPEPLNAHAGIASAEIKEKVGKEGARTIPGRPEHGGNCDIKNLSRGSKVYLPVHVAGAKFSVGDLHFSQGDGEISFCGAIEMAGIITINFKVLKNGVANLGLKSPIYIPGPVEPQFSPGRTLYFEGFSVDEHGKQHYMDVTVAYRQTTLRCIEYLRRFGYSDYQIYLLLSCAPIQGHVAGIVDIPNACTTLGLPMDIFDFDISPAAVATSGSAPTKLDMGACAFETGVAEGKVTAGGKNSEHSFGGGLTYKASVVDRVKGTVTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8Z1</accession>
    <name>A0ABR1X8Z1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002250</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673861.1">
        <property type="nucleotide sequence ID" value="XM_066806565.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039625"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF230">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="268"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="62"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8091889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="470" mass="51048" checksum="547EBB2F94701E23" modified="2025-10-08" version="1">MDAASNPTVHLQHMPPGVQPESDATFEQLRQSLSRVVSRGSKGVVDSGDLPGNPPFPEGGLRAWLVVLSAFAMSFASFGFMVSIGTLQSHWHAHQLAHLTSRDVGWIPSVFTYLSLALGLWVGPLFDRYGPRWIALGGSAGYLLMIFLLAECTQFWHFLLCCGVLGGVSAAALTTTPLAVVAHWFERRRGFAQGVVMIGSSFGGLTLPLILQATIPKYGYAWSIRILGFIFAGCLLISNVLMKARIPPLRSRRNHPQAQREKKPDQPIISLAIFADLRFTLLTVSVFGFEIVLFSALGLLPTYAALVNPAAETTGFYLIALLNGVSCLGRLGPGWFADKVGRFNMLLAMTVFTLVWMLALWLPLGQTSLGALYAFAALFGFGTGGWMALTPACVGQLCRADEFGRYYGTMYFVASLATLVCIPISGELVESVGPTAYVVFLCAVLGLSLISFIFSRWACLGRRWLVMAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X929</accession>
    <name>A0ABR1X929_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha N-terminal protein methyltransferase 1</fullName>
            <ecNumber evidence="5">2.1.1.244</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">X-Pro-Lys N-terminal protein methyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_002347</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54712"/>
            <dbReference type="Rhea" id="RHEA-COMP:13785"/>
            <dbReference type="Rhea" id="RHEA-COMP:13971"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138057"/>
            <dbReference type="ChEBI" id="CHEBI:138315"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54736"/>
            <dbReference type="Rhea" id="RHEA-COMP:13787"/>
            <dbReference type="Rhea" id="RHEA-COMP:13974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138059"/>
            <dbReference type="ChEBI" id="CHEBI:138318"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54724"/>
            <dbReference type="Rhea" id="RHEA-COMP:13789"/>
            <dbReference type="Rhea" id="RHEA-COMP:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138061"/>
            <dbReference type="ChEBI" id="CHEBI:138317"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. NTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.244" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673958.1">
        <property type="nucleotide sequence ID" value="XM_066806662.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039722"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008576">
        <property type="entry name" value="MeTrfase_NTM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753">
        <property type="entry name" value="AD-003 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753:SF0">
        <property type="entry name" value="ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05891">
        <property type="entry name" value="Methyltransf_PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016958">
        <property type="entry name" value="DUF858_MeTrfase_lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="127"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8091986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="270" mass="29547" checksum="6FFBE788BFD7A7BD" modified="2025-10-08" version="1">MKEQQQTEGGEGENEDGEEGEWEDEVQEPPPPDSLIRTENQLSYWSGISADVNGMLGGFPSISTVDLRGSRAFLVKLGIGKTKGLHKIERTLEGGAGIGRITKGLLVDISQTVDVVEPIAKFTEELSQTPGVGQIHNMGLEEWPPSTSPSTTTDDDSSSSPSSPSRKYNLIWLQWCLGHLTDTQLVAFLRRCRDVLVSSSDSSPAPAIVVKENNATSDADLFDDLDSSVTRTDEKYHALFREAGLRLVRTELQNGLPKGLYPVRMYALKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9W4</accession>
    <name>A0ABR1X9W4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674166.1">
        <property type="nucleotide sequence ID" value="XM_066804393.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037453"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="207" mass="23041" checksum="D9B3838D0B4E7E5F" modified="2025-10-08" version="1">MRRSGPEFARIARLQGKAPRDRRRVRNPLILDFESDYEQPDDDESDDDESDECSDSEGHTGHSIGGSDDGRSANGVAAREPGPPEGGSRSDALHSSQAGMPAQIKADHGQLPADLHEFLQWVFGPQGIRSLRLFLYGDFSFNGRFKDECKMMCRNETLESQQTAAGQGVGPRLHYREVTKDDRDILNLLEKQEEFVTACPVDRTFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9X6</accession>
    <name>A0ABR1X9X6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable beta-glucosidase I</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Beta-D-glucoside glucohydrolase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cellobiase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Gentiobiase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_000062</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674150.1">
        <property type="nucleotide sequence ID" value="XM_066804377.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037437"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56988">
        <property type="entry name" value="Anthrax protective antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="11">
        <location>
            <begin position="145"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8093377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="426" mass="44987" checksum="942542F9AF21C31D" modified="2025-10-08" version="1">MRGQNLLVSLGNRKVSQHALNDRVRNLLTLANKVAPLASEGNASEDVNNTSEARALMRELAVAGIVLLKNDDSVLPLDKSKSVAVIGPNAKIAAYAGGGSASLRPTYTTTPYEGIAQHAKDLKYTLGAHGYKQLPAISLMSTREDGEPGMTCRFFNEPPSEDPGGRICRDVVQTDLSDMLLVDYSHPDIRQDVWYMDMSGTITPAESGEYQFGCSVRGTAKVFVDGELVVDNATAQRQGATFMGAGTLEERGTKTLEAGRTYAVLLQFGSSPTQKIRKVGATAMRGGGVRLGCTKVIDADEEIAKAVALAKEVEQVVICAGLTAEWESEGFDRADMALPGRTNDLIRAVSTANPRTAVVVQSGTPVEMPWAAAVPALVQAPYGGNEGGRALGDVLFGAAGAAPSGKLVYTIPGARRGQPGLPQLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAE6</accession>
    <name>A0ABR1XAE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674346.1">
        <property type="nucleotide sequence ID" value="XM_066804573.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037633"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="503" mass="55448" checksum="568749017E2CCF84" modified="2025-10-08" version="1">MEEPHRAGRSAQFISSDWRRRGAYALAICWIVGSAIGMIFAFRASDSHQDDYYKAVATCSTDGSFIPFHTSKGPWKTSQFFAINIVAARSLSFSVAKFIDVVWDVIGGRGFAVAMAVLSFKVFRQYLTVSMRRHPVTYQVFRAIYLESEPSIVSTYRLVKDGITGKRRVVPATGLVFMVATLVFVLIFPTLSGSMTGYINVSRGFVQASGGDMVPFESLDFVAYVIHDGWRVNLTGDYIISLGVEGGHEYTQKIGDSSSWILPLVGGAKLDVIFSSGILLTGWTPQDVWQYGFYGLHNNTSVWPTDHGNVTLAAPSLNISAFYLDDVSGSIGDGYGHEWVDPRTGQKPFSDEGRVGWTAANQTFTMEDIVTNSTCQPVQNVSTCSVRFLQQYQWGFSLIQLLIAAILLGVWIIGLCVMSYTSNRHNPLEGGQPEVLQGWRALLTLAEAMNLELASSGIEPHVLKDDELQKQIDRHIGGGRVYSKSGGDNIMERRGFPCAEEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAY2</accession>
    <name>A0ABR1XAY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000506</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674594.1">
        <property type="nucleotide sequence ID" value="XM_066804821.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037881"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027372">
        <property type="entry name" value="Phytase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37957">
        <property type="entry name" value="BLR7070 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37957:SF1">
        <property type="entry name" value="PHYTASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13449">
        <property type="entry name" value="Phytase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047048950" description="Phytase-like domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Phytase-like" evidence="3">
        <location>
            <begin position="145"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="55627" checksum="45ED951BDA283E58" modified="2025-10-08" version="1">MLALFAAAMAVVGRVLETADISSPSEGAVNATTCASKAYTYHELAGYGFIAADAVDKFGDTLGGLGSAIHMDAAHWTRLDNGSYTGTLWSLPDRGWNTEGTLNFQPRVHKFGVLFTPAPNATMEEPSPPNLQLRYEDSVGFSGPDGSPCTGLDADAAGHLSYEGFPDLPVATYTGDGFGGEGPGGRRVAVDCEGLYVNADGSFWVSDEYGPYVYHFDPTGKMVAAIRPPDALIPNRNDAESFSSANPPHYLGGESGPLPDPEDPDSGRDNNHGFEGLSVTDDGKTLWVLLQAATVQEGGLEKQTSRHTRLLQYDVSDRLRPVYAASYIVPLPLYVDPTTSKPSKNPKVAAQSEMHALPNGQFLVLARDSNAGRGAESAESVYRQIDVVDLGGGATDLKAAKKDYDCSDCGAASKKKGKLKDEVTAATYCGWLDFNVNAQLGRFGLRNGGEQGAGLLNEKWESIAVVPVNPSAPDDEYFIFSLSDNDFITQNGFLNGGKFRYADSSGNSLDSQALVFRVTIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBK4</accession>
    <name>A0ABR1XBK4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674735.1">
        <property type="nucleotide sequence ID" value="XM_066804962.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038022"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045398040" evidence="1">
        <location>
            <begin position="24"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="304" mass="31700" checksum="716FBD2069B022CA" modified="2025-10-08" version="1">MRGLNSSISFWVLGLLWLGQANAAAMGSPRSAQACDATCSQCTDTEGGGSRCCLEGCGYGCDDTSVVWDECIKAGCCATCVDCEGTEYSGGRSGPSKITEQGPFNASVRFPDLIAGRQREVELPGPEVECERREEGRGELRAHDADFAGRLGQGGLGVVREVAVVEETGPVRGSAQARLSVLESVGPEVQAAAGVGETRVEEGDGQDGVVGADGPEAEGVVFGGRAGEELFDEQGWHEYHETNVLPPANTTRGNGVGAARKPQKVMAAANGPPFEGVELGESTRGTLKTEKELSQVILQSSSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC29</accession>
    <name>A0ABR1XC29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675028.1">
        <property type="nucleotide sequence ID" value="XM_066805255.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038315"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="682"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="718" mass="80290" checksum="58BEA579F28805F6" modified="2025-10-08" version="1">MAAATFDRDSDVPLTPYSPYRDDFDIEHDRRGDTKDLANDPEAGGIGRRTNSPNPLGRFVNALLIIFFCFIGVYGLLKAIQCYNTADTTVTQGPVKGVDWGLDFPLHYPPLAQDGSSDACRAAWDSLSSINCHEKIFTHDWDNATHELVQYLPDLCRPGCRKELVESTQRITKECSAAVFDAKDYNGTFDVNSWGRGPAEALQVLLHRNSYTCRPSEHSRFDYCMEEMIQTWGIYDGENHTSLDGLSSFMATGGGGQNRNCGSCTLDWLENTLNEWKPSQVLSPDTHVPISLPEHLRRVEQAGQTCQKEDWEKMWGDAIRRYTEEGSLSSDWRNMPSGDYGWTVRNGLVSPADGPRPAIHKALESISAKGQPSPQSPMEDAYKCLSALENQVATLPCDIHLSKSQLDSILEPRNPLFDSYCRQECTDEIVRHQDNLASCRSKNMENHAVAGPLYTAYKEAEERRSNICRKPAVEDTSCAPIFVKLHHPEWAFDTRLAISSLEPLLGELERQPIPITTSLIGGKSTPSLSPKSDAPLWDQIAGAHDAIRTGICSRCVWETVVGNGTISSAQHSLEGVDDVDAYLGFADRLYKACTARGADWLGGLPYGGDDAVWRIQDVDGSVSRLIEDESSSPSNRGVWIQAYENTSLVKIRKHIYGSIWHLRAAGRRVKAEKQGNLTQFLAEESKHREEEDAKVWRHGDPKFQSWEWIQPQPEDHQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC78</accession>
    <name>A0ABR1XC78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protamine P1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674976.1">
        <property type="nucleotide sequence ID" value="XM_066805203.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038263"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="767"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="889"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="725"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="837"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="900"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1047" mass="114561" checksum="3DCEAF4462F51933" modified="2025-10-08" version="1">MDMDWWEQAQPREEPLHCAAPQSPEDVLYLGSDDGLDDATKAAKRRRYEEKGRQYLRGRPLRLFSASLRGPFEKSSGWQNPWLPKNGPLPPSSLRPTITKPAVKAAIRRNIHKLEGTANSTPDTRGSMQCHLPSPESNRDFQLDDHDGLDPDKRSRIKSWAKNVTTGALEKDSFWAPAQTKLPTPDNVTNKRPAENNWLKSKLLKRPPLPDLDIVANSSGAAQGMAQFVEGSSQAIAESSYPGLEQSPAPHSSTKDLNPMSLIPSDANVPDRLPASNDIYSETSSELSSLRSSQVTPAYPIRDIEQTDDLPNFETADKFHESVENATASGDSHTEEADSNFESHLDQSFHYKTRPSRKDATRPVTAEPAATVPLSQPTQTGTPVSENHQDSVTFKARQTRRDDIDTIFPQCASSISVSVEDPQSDTKTPSVIDNEETGASEKLNHYHHHLRLSFHQRPNSKDSESRLPPNQDIANPDQPKSLPAVGDGDTTLVVDAMGVDGQLDNTSFFHPPERLDMVKYAEGAPLLTSLAARASSLVDSRQVSVEQPVSTNSPISLEGEKRGMIDNASPRHESDGEETAVHIPLSQMEWGIGERETHSPTCSFSAAVEKPLSPFSNEAVESMAGNIEQVLDNSTQQELLSMEAQSDAANTILHIKTEPDEEVPGLAAYNTSMSGPSSIVLDQSALRPSQQSPWGTVDADVLLEVKNEFQATNLAVPRPDLGTLPNSASQLPSQQQSPWGGVDARTPIRPYGSIPVSSLLNVTPQWSSRSQLEDNPSNSVRSHVSFASQPSGTLNSFIRGRVSSSSLETPQAAQRREETPEPELSVKSFAKFNTPSPKRKRRGYKHPRLSGSRLPSTQVLVDATNGNPWGTQGSRSNLRVSFAPLPCEEKDSANTVSPQAPRPASPPPAITPRADDDDTDHHFWKHFDAVKSRGGHPSKADTQERLLPSESQQRPVSPEVGAMAEAFREADTFHISNLLEPRTSSAQEDEEALPVGSCQKDEPAIDTPQSPWREESQGLDAVAEVMQNLDDFLNPQWGEESDLGMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCT3</accession>
    <name>A0ABR1XCT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001098</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675186.1">
        <property type="nucleotide sequence ID" value="XM_066805413.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038473"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="622" mass="68244" checksum="6767250865369EFC" modified="2025-10-08" version="1">MVAAVGIDLGTTYSCVGVFRDDRIEIIANDQGNRTTPSFVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLIGRKFADQEVQADMKHFPFKVIDKAGKPVVEVEYKGETKNFTPEEISSMILIKMRETAEAYLGGTVNNAVITVPAYFNDSQRQATKDAGLISGLNVLRIINEPTAAAIAYGLDKKVEGERNVLIFDLGGGTFDVSLLTIEEGIFEVKSTAGDTHLGGEDFDNRLVNHFDLSGNARGLRRLRTACERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCQDLFRSTLQPVDRVLADAKIDKSQVHEIVLVGGSTRIPRVQKLITDYFNGKEPNKSINPDEAVAYGAAVQAAILSGDTSSKSTNEILLLDVAPLSLGIETAGGMMTKLIPRNTTIPTKKSEVFSTFSDNQPGVLIQVYEGERQRTKDNNLMGKFELTGIPLLPVIEVTFDLDANGIMNVSALEKGTGKSNKIVITNDKGRLSKEEIERMLAEAEKYKEEDEAEGRRIAAKNGLESYAYSLRNTLADSKVDEKLDASDKETLKAEIDKAVAWLDESQAASREEYEEKQKELEGIANPIMMKFYGGAGGPGMPGGMPGGAPRWRCPRCRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE54</accession>
    <name>A0ABR1XE54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675734.1">
        <property type="nucleotide sequence ID" value="XM_066805961.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039021"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="74" mass="8149" checksum="82BB82229113627B" modified="2025-10-08" version="1">MTGLWPVNIQKPINNRLRRSATLRAVDEALAAEEASRPPEPELGRIETPKTGRQLKDLGVTYLGKDVVGGDLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTS2</accession>
    <name>A0ABR1UTS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660922.1">
        <property type="nucleotide sequence ID" value="XM_066818734.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051794"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="20206" checksum="9243B7A75AF760F1" modified="2025-10-08" version="1">MASRELLSELLPATPLVLGVIGYTLATFWAEGLMRKRAPKLYSQLQGNHRALLYYTAMAVGKGLAVLFVPACALAAIQGNGTAAAVMGETPWQATTVEKVCVTSRIAIWVGEFPRTQLYPGLVAHHIWSITSAVLILAGGQPPQQLYVMYAALLTENFGKVGLKFQIIKKNGPDSPLKKLADKKETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU37</accession>
    <name>A0ABR1UU37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-ketoglutarate-dependent dioxygenase AlkB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661038.1">
        <property type="nucleotide sequence ID" value="XM_066818850.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051910"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="26731" checksum="8487A319D1CE5653" modified="2025-10-08" version="1">MFEELWVSVQDGAIPLERCPVSTKIPGQLTRFFATNYGEENLAKMTTSTTSFGEAPEVIRLVKDELTAVVREILGEEVNFNELLCIGNYPNMAMNWHKDREKGVGPVVASFSYGGTATMSFSMDRQHLVGRGRTNGAYLYDTIFPGCLGKRKRSLRKKRDEGRITEEEYKESFRALVDKIKMPSTKNPILQFPLPGAATVMIQVDKSLNQWFEYTVEHNGIARLVTTCRSIEHDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1E2</accession>
    <name>A0ABR1V1E2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PR-1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011752</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661759.1">
        <property type="nucleotide sequence ID" value="XM_066816067.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049127"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047010880" evidence="2">
        <location>
            <begin position="26"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="54"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="214" mass="22549" checksum="82547B2A4BF333FA" modified="2025-10-08" version="1">MFIPSPLPTSLLLGVTLLLSSQSTAQDVIITKTITSGPSEATASAAAEFMSADLFTSAILNSTNTYRDQHNASHLVWNRTLEDFANRYLGQVVSRSLSSSDSESESNSSTTLDSRDSLSRRGGKCDFKHSGGPYGENLALGCSNATSCVEAWGNERRDYDFGTGDFGESTGHFTQLVWKNTTSVGCGARMCGGDGKAGDARGGTWCASTGRGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2T4</accession>
    <name>A0ABR1V2T4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cloroperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012247</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662253.1">
        <property type="nucleotide sequence ID" value="XM_066816561.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049621"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF7">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046576589" evidence="8">
        <location>
            <begin position="19"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="20"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8065500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="250" mass="27965" checksum="BC373237B801EB6E" modified="2025-10-08" version="1">MKFFTIIITLWVATLGYAHPHLHWTPPGPGDVRGPCPMLNSLANHAYLPHDGKNIDVAITKKALLDALNIDEDLGQFLFENAIITNPVPNATAYSLADLSRHNVLEHDASFSRQDAHFGPQDVFDPKIFAETQSYWHGPVINVTMAAQARQARIRTSNATNPEYSLSPLGRGFSLGEAAAYLIILGDRDNHTARKNVVEYLFENERLPTKLGWQRPEPLVTFVELQDVMGKLYNETDPDIRTLARRGMHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2W1</accession>
    <name>A0ABR1V2W1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012268</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662274.1">
        <property type="nucleotide sequence ID" value="XM_066816582.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049642"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="282"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="229"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="353"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="448"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="501"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="516" mass="55601" checksum="127A9A14BF5D92D9" modified="2025-10-08" version="1">MSPSSSPAPSPPAVSSPSANSNHPTLPPLITSPTSSRASAIPPPMSHASKNRLSQYSVGSVPSRSRPPSYLFPIFHSSLTYTIVRDFAYPPIHPMHYGPPPEGSRPASDGGLGKGERLAPIHFGDGPPWSEDEDLQSPVVSSRHKKHKSSSASLGHQKSRSAQEHGTLGSPSMMNSDSYDRQRGYFTGTTGDGSERYYVSQGEEANGPGGEYVTYPSEQLRQSMQALYQAQEPKPRQYMEHEAGYKSESDVSSNASSPGFRPYDESRYSRDYQFTITSPDEEMHGKAVALFDFERENENELPLVEGQIIWVSYRHGQGWLVAEDPKTQESGLVPEEYVRLLRDIEGGMNSLTGDLGVAAGTPNDTGTPTQAEHADPSAAAASTSGASGNSSGHTPSQSTSSTNGYHQPVVSTFSTSSKDLDPYPPHLLGSQTGQPPPQVVHYHGQRGGSQANTPTAQSSFDSGMGRRGSQDTIGRSDSSSRKSQLLETLPDKKLTSPVEETSSELDQEQDNESTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3N8</accession>
    <name>A0ABR1V3N8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012289</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662295.1">
        <property type="nucleotide sequence ID" value="XM_066816603.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049663"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052246">
        <property type="entry name" value="Cell_Polariz_PKAAnc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13155:SF1">
        <property type="entry name" value="A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13155">
        <property type="entry name" value="A-KINASE ANCHOR PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="188"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="379" mass="42618" checksum="B74A37FF4D52A5BC" modified="2025-10-08" version="1">MAYSGHEPPSSFSRGTPSPIPDMTRNRLPTLFEVLSRRTHPPVDLFSFYIYMRDQQRSVDYLDFWLDVAQHMSLCRHYVRELRRSVLVGTPDGESRSKRSSAVLEAMGEMRDGPAGPSHYSTEKEREQNAQMSAYLRDQPVTPGTPGMQHQDSPASSQERRARASSHLSTPRGLTTDSNSPAHAVAREDIRASAEKILYTFLLPGAEREITLPGSITQDITTAIEQDGRDDPEVFDVAKDYVFQAMERDAFPGFLRARALGNLIPPTIIARLITGLIAMFGAFWTAFVLIFLNMSRQTRCWVILPFTVGVYLLASYQYSLDPIMGLIGFSEYTPFNFSRITEPYVRKLLVKRSLMVLGITVLIDAALCVLFILVPGKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3X5</accession>
    <name>A0ABR1V3X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662642.1">
        <property type="nucleotide sequence ID" value="XM_066816950.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050010"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="334" mass="36588" checksum="F615FD3BA3E4C508" modified="2025-10-08" version="1">MVTETEGREIYASSIHFDGLNICNWSRDICEAWHKGGITGVSCTCGLWEGLRGSLANVIQWKRWFEEHSDLIMQAHSAADVRAAKDAGKTAVLLSWQNTAGIEDQLDYLRVFRDLGVRKMQLTYNTQNYSGAGYTELNDSGLTGFGREVVDEMARLGIVLDLSHVGPKTSEDAILYAPAGKPPCFSHVLPAGLKDHPRNKSDHLIKLIGSKGGFVGLSQFGPHMAKGNDSTVDDYVDALDYVIGLVGEDLVGIGSDASEGHGRPSEFMAWCNKDKGYARQLTPWGSQKVIKPLGPLADRAELACAMARKGWSEEKMRKVLGLNWLAYLEKIIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V432</accession>
    <name>A0ABR1V432_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Elongation factor methyltransferase 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012696</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662702.1">
        <property type="nucleotide sequence ID" value="XM_066817010.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050070"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025784">
        <property type="entry name" value="EFM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF10">
        <property type="entry name" value="PROTEIN N-TERMINAL AND LYSINE N-METHYLTRANSFERASE EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51560">
        <property type="entry name" value="SAM_MT_NNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="29738" checksum="865454EC573B1404" modified="2025-10-08" version="1">MELEEDLDQTNLFEEPADFAPPKPPTKQIFKLESGKEITIHLVGYNLYEGHYLWNGSRFVSQWIESHVPLVQGKTVLEIGAGGGSAESGARKTVVTDYPDQDLIVNIDKNIDEARELLPTPTRDYIVADGYKWADDPAPLLAHINKAGTDQTEKFDILILADLLFKHPQHKNMVKTIQMTMSRRRESRAWVFFTSYRPWLKEKDLAFFDLAREQGFDVEKVFETRMDKPMFENDPGDLEVQKTCTGWEIRWPEDQCEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4F2</accession>
    <name>A0ABR1V4F2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">E3 ubiquitin-protein ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_012824</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NOSIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662830.1">
        <property type="nucleotide sequence ID" value="XM_066817138.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050198"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016818">
        <property type="entry name" value="NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031790">
        <property type="entry name" value="Znf-NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063">
        <property type="entry name" value="ENOS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063:SF10">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15906">
        <property type="entry name" value="zf-NOSIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023577">
        <property type="entry name" value="ENOS_interacting"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="268"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="121"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR023577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8066077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="377" mass="41997" checksum="8706648D9CC11B64" modified="2025-10-08" version="1">MSHSKRNTSRAVFTSHEREQAKKAWSSTSATLSRESFLPFSSCRLCLEPALDPVACTHGDLFCRECALSNILAQKKEIKRLDKLREAEARDRDEDTARQKAEEQERAVREFEMTQRGLDVAGRKLGEKKKKPTQDTTTVPDTIPEETRSSNGTTGTKRKFELDDQELSRIASEDRAKARKALEDEKAAKPKLASFWVPSITPTSNTKDTLHEVTKKAKTTPTCPASPEDKPHTYSLHTLVAVHFTEEEEEGNGPAQKTGKSKKMQRVCPSCKKALSNSSRAMLARPCGHVLCRNCVDRFMRPSGHHDPHAEEVDPEGLRCYVCETDLVDRGDEGATKNKKKEKERIRPGLVELRSEGTGFSAGGANQVQKSGVAFQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4H9</accession>
    <name>A0ABR1V4H9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-dehydrosphinganine reductase</fullName>
            <ecNumber evidence="9">1.1.1.102</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_012833</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>sphinganine + NADP(+) = 3-oxosphinganine + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22640"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57817"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.102"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:22642"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.102" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662839.1">
        <property type="nucleotide sequence ID" value="XM_066817147.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050207"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08939">
        <property type="entry name" value="KDSR-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045022">
        <property type="entry name" value="KDSR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550:SF3">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8066086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="375" mass="40905" checksum="98CAAFA6AD131A77" modified="2025-10-08" version="1" fragment="single">SPPCLLSTSMSSYFYIAVAVVVALISVLAMGLFGGGNHMPVDGKTILVTGATEGMGRCAARQLAAKGANVIVVSRNVARLEETVAEIKVSIPIDIWTENIPYSTLTFRLKSAAKNPQTQRFHYISADVSKSDYARSLIAEAVAWNNGQSLDIVWCIAGKSTPDYWFEAPLSLSREQMDINYWGSAEMAHAILREWCAPDAPVVPEPKHLIFTASVVAFFPVIGYGPYSPPKAALRALADTLVQELEVYPQNVKVHVVFPGGIKSPGFDRENQTKPEITKIIEADDPVQTPEEVASKAIQGLENGNYFVTVGLLGQFFRWSAQGGSPRNNWIVDYVVGGVTQIAWLFALPDIYGKIRKFAKKNGHPGSYRNKANGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4K7</accession>
    <name>A0ABR1V4K7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_011942</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661949.1">
        <property type="nucleotide sequence ID" value="XM_066816257.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049317"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF13">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="489"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="64"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8065195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="551" mass="60374" checksum="3F5DB46554863345" modified="2025-10-08" version="1">MEKRDDVDVHETHEQYPEKTNIPPSPTQANVQHTVIKGNEAFAAALVSEPPNPWARTQIMLYVFSIVGFFCSTMNGYDGSLINNLLINPAFLEYYHAENAGIWAGIISSMYQIGGVVALPFVGPAIDTFGRRIGMVIGAGLIIVGTIIQGVSTNADTFMGGRFLLGFGVSIASAAGPMYVVEINHPAFRGVVGAMYNTLWFSGSIIASGAARGALNTGGDYSWRLITWLQCLFSGLIVLFALFLPESPRWLYVNNKKEQAMNMLTKYHGNGNPDSPWVKLQMSEYEELLNMDGADKRWWDYRALFRNRASAYRLGCNVVISIFGQWAGNAVLSYFLGAVLDGAGYHHPIEKANITLINSCQQFLCAIVGACLVDRVGRRPLFLFSFIGCTVVWLGMTIASAEFEAGGGSKDSMGTNPGASKAAIAMIFIFGSIYSIGITPLQALFPVEVLSFEMRAKGMAFSSLAVNVGGLLNQFAWPVALQNITWKTYIIFTVQDAVQAFIIWWFIPETKNRTLEELDEIFAAKNPVKASIQKKHVAVTETGNVVDIHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V571</accession>
    <name>A0ABR1V571_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutathione S-transferase UstS-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661902.1">
        <property type="nucleotide sequence ID" value="XM_066816210.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049270"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione S-transferase UstS-like C-terminal" evidence="1">
        <location>
            <begin position="102"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="231" mass="26455" checksum="ECDFC52EA8C1FD6D" modified="2025-10-08" version="1">MAANQITLFDLPSQGRCATWSLNPWKTRMNLNFKGVDYKTEWLEYPDIKPRLEKHVTLPEGQTTYTIPTLEELYPEPKLAGIETPAFDRLTKDLLPGIMGDLRPVYFSRLPERVLNQASYEYWQTTRAEALGLGKRPDELTDADRDAAWAKLAESGKLKQVSALLSAQAANGPYFEGKEIGFVDFAWTGFLVFWKRIGGAEWEKILELTGDKDLHLKYLQKMEPHIKRDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5C4</accession>
    <name>A0ABR1V5C4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">nicotinamidase</fullName>
            <ecNumber evidence="6">3.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Nicotinamide deamidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012258</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; nicotinate biosynthesis; nicotinate from nicotinamide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.19" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662264.1">
        <property type="nucleotide sequence ID" value="XM_066816572.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049632"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01011">
        <property type="entry name" value="nicotinamidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052347">
        <property type="entry name" value="Isochorismatase_Nicotinamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080:SF2">
        <property type="entry name" value="LD05707P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080">
        <property type="entry name" value="PYRAZINAMIDASE/NICOTINAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="8">
        <location>
            <begin position="6"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="259" mass="28918" checksum="E0FDC53CB0B3CDBB" modified="2025-10-08" version="1">MVIRPALIVVDFQEDFCPPVGNPSRITSPRRHHKADVELQNGSLAVPEGRDIAPVVNQLLSLPFVTKIATKDWHPASHVSFAANHANKQPFTDYATVVNPANPDERYETRLWPVHCVQSTPGAELVPELEAGKIDEGAVVEKGQDPRVEMYSPFYDRFEHPRGCDSGLAKRLRDAQITDVYVVGLAADYCVRSCAEDAAKEGFRSFIVEEGTRPVDKDNWTQCRAELEKQGVRVVTMQSDEMRSTDYPTYNPARNPANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5K1</accession>
    <name>A0ABR1V5K1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663231.1">
        <property type="nucleotide sequence ID" value="XM_066817539.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050599"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="80"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="625" mass="71618" checksum="357660042E121C5B" modified="2025-10-08" version="1">MRLQPWTTRLRRKNTVAAERATGLLPAEVQSQLYSSLASLYLPLDESKQEFRIVTIAAGRFEDAIACELEVVSPVDSKPFEALSYAWGDSQPSWKVYINGTRHEISRNLDSALRHLRHRNRSRVLWVDALCINQTDLEERNSQVKHMGTIYKMSSQVLTWLGPEYNNSDMAFDFFETMPRDPDVHWDPANIPELEEVYTLRHTIAGNDLFDRAWWHRIWTVQESGLCPKLHFVCGARQLPAEEAFKLGVCYFKHLYTCCQDIWYARFKSTAGQPGLGDVCTALGKLEEMRATNHRYTFGQILSKFMSRHCSDPHDKVYGLLGFADKEEASLVVPDYAKPVAELYEEVALGLIQLTEDLEILSMRLPDSYKPERLPEGFAIENLPTWVPNWSLDWDSPLLHDLDDRLSCLSYYNASKGSRYSSNSVACGLLPVRAQFIDQVAILSKDEDHMDAPNLAEFFQDWRNMLRITENPGQLYAKCSSITVDDAFWQTLCCDDSPHRRWFRAWWEWCEQHGCDPHQLMSIQSEYSRAEINVMGGLISTSIKMRRLFISKDTGWIGLAPVDTLVGDKVALLEGGRTPYILRPTNERGVKETIQKYRLVGAAYVHGVMDGSEWQDDALEYIVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6G7</accession>
    <name>A0ABR1V6G7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662669.1">
        <property type="nucleotide sequence ID" value="XM_066816977.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050037"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="48156" checksum="C34642BF0F97E36D" modified="2025-10-08" version="1">MALSRIEQLSPELKQLVLSYATDWPSLRSAVLSCPEFYAAFKSAEQWIATRFVKNLIDIDVLPEAYLAQGLRNLTVVWPYPEAAHTIETWLAVELRKKRRVTDEKLTVRDAIAMSRLHHAVESFVDEYIRYCTPLARGSTVPQPVTTLAEKPLTRAERSRMSRAFYLLEMFSRLHRCGAPCAQQGLKFPVDIPVTHPFFAALPPWEKEQLRCINWCLKAFYERECVQPLFPQQTYFADTWNMAQEKKDLWYAIQDRDLTRLGLEALHEASISPDSARREEIMLQGRTAYELRREDFPPQLDRILDNLERIPEWDMPGKPDGLEVYVRGASLRGEDADPGPRAVWTWVNEGTGWGRYDPHLRGSLGDRQRETIQVVRWTGLVFWDHSRLEAAGVFSRDSRSWVTSAVSFIDLGRRTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6P3</accession>
    <name>A0ABR1V6P3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012647</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662653.1">
        <property type="nucleotide sequence ID" value="XM_066816961.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050021"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF129">
        <property type="entry name" value="ASPYRIDONES CLUSTER REGULATOR APDR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="44"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="516" mass="57217" checksum="4A19E52813440705" modified="2025-10-08" version="1">MASLCKEVASRRSSLKHHRTLELNEPLPDLACTLPPKATCDQLLSNYWRFFEPLFRVLHRAAFEEEYDSYWAGNTKPSTGFILKLSMVLGLGAVVHQDLAESGRIRGLAKSWLYAVQWWLMGPMEKTARSLDGVQTFCLAVLLRQASSLGGASSISTDSLLKLAMSVGLHLDPDGFSVYGPFERELRRRIWHTVLELTVMTSLDTTLPLLITPDDYNCRPPLNLSNADFGPNSEEMPQARPSALGFTDSSTQLLLQKSLVRRLYAVRRMNGIQKPLSYEETIELGKELKMQSTYGGASCFCIDHSRSRQGRTPRYHLARKTCLECCQIVSSHAAGLTLPQKVTDEFCLMAIRGSGLFKGPLSQDVIIHLGLEVVTQLEEERDLRMPGEPATPTSCADPLIQMSRAGRQPLIDTLRHILGQLRQIIALGQPSCKRYFLLSAAMVHIKELEAGSSNPLPAAMSQLTECLQDCSELLRLASADVSQPVTDSDPAWSDEASPDWSDTLGLFGFDFDLLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6Q7</accession>
    <name>A0ABR1V6Q7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013633</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663639.1">
        <property type="nucleotide sequence ID" value="XM_066817947.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051007"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="161" mass="18204" checksum="3AD384880639D06F" modified="2025-10-08" version="1">MEDVDHTISWRKQGRYRDEPVTVRWALDGGVTWEFNTTETHAIFNPQRIVRELYRDVIRQSLGGSQAASNNSSYSVRDAVPLYSLYNTVSNMVEITLPVAADRKVNSSSRADSVPYIRSDRFIVASSLAEKFLEGQRRLSHEERRTWRLGVGVAVGLGCPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6T5</accession>
    <name>A0ABR1V6T5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663685.1">
        <property type="nucleotide sequence ID" value="XM_066817993.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051053"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="60" mass="6685" checksum="8B45B1BE71530DBD" modified="2025-10-08" version="1">MSTIAACECNLLQTLITHSLNNKIILKGENEPDKFADVKLDFQTRSNGRTSYDNTDKPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6Z8</accession>
    <name>A0ABR1V6Z8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663706.1">
        <property type="nucleotide sequence ID" value="XM_066818014.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051074"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF157">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="10"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="323" mass="35830" checksum="C23731D646B715DC" modified="2025-10-08" version="1">MILSTAAIGLRFWAPRQQKAPLMIDDWTATVALISHIGTTIPSMGISHHSRTSLVFIELPVVYRKGLGYSSHDFTPEQQEARNKTDRVFQMVLNILTRSTLGFVKLSALVFYRRLFCTGSKTTILGVLTWITIVVVVLWLLAFELFAGFQCGTGFSELSEGSMPDICTLVLPSSLGLAISDFLLDFWILVLPIPGRLRAADLNQPIWTDRLTRLVFYGILECGMAIIAVNLPSLWVLVVPLNTTELVDYVKSVLRKLSCLRGDDGSGVGSDPVGTRHADDIKSIESFSTGPMVTVEEPRHDYLQVRLSFPEDPESRSWGVIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7P1</accession>
    <name>A0ABR1V7P1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663970.1">
        <property type="nucleotide sequence ID" value="XM_066818278.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051338"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="119" mass="13336" checksum="45CB1CAD0CA9BAE3" modified="2025-10-08" version="1">MEANNKKPEAQSGGAAAQPQRSSVNPFKEVFEVSRKTIEIEEKDLESKVKAWRDNDDDDKNAEFEAKIAVSRGRLKENVDNAVGVVKRAEGYAGVREEAAELMRLVRRVRREHLGEGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7T6</accession>
    <name>A0ABR1V7T6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663134.1">
        <property type="nucleotide sequence ID" value="XM_066817442.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050502"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF6">
        <property type="entry name" value="ALPHA-L-RHAMNOSIDASE SIX-HAIRPIN GLYCOSIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046105456" description="Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="2">
        <location>
            <begin position="307"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="829" mass="92265" checksum="C878C7469CC143A1" modified="2025-10-08" version="1">MAQKLLPLLFLATLGLTRTVGPDGIDYHHLPREPVFPGPWDRFIQAPANKSHIKPARIWTVEGNVTTTSTSTGGYLSAGSSILIGEGGHITLEFEENISGRVCFQIDSVMDEPVLMLAYTESSFFVGERTDATNDDPWDLPLEFHPGKKTGKMCVGDDFLRGGFKYLTLYIDDIPVFESPIARTFRQLFATIAGVAQKVLLGKDPILQLVGQGEKRPYSKPSIGISQVWVNCTSFPSQPNGRAYSGYFYSSSDLLNRIWYAGAYTLQLSTIDPKEGSALIHVNSFLTHHQSPPGSWYSNFTVSQGTAVTTDGAKRDRLVWPGDMYIAIPGIAVSTYDMLAVRNALDIVYWRQYSDGRLPYAGPPLSYHNEFSDTYHLHTLLGTYDYVMYSGDIDWLREKWPDYMRAFYVSSSKVDSRNLMHVTSPFDWNRHGMGGHNVEASAILQVVLKRTIELSSFLAFDPLIELPDKDYLESLIERLESGIEALYCNHTGLYSDNLQDRHCFGDDHCDPQDGNSWALIAGMAKTFPSQPYSISEGLRARWNKFGAPAIEFPNVMSPFSSSFELQAHCAAGNHDAAVELMLLMWGYLLKGPGFTNSTLAEGFRTDGYVHYPAYPIPSRNSHAHGWAAGPTSTLTTGILGIKLLKPGGDEWSIRPVLSSWLGWARGGFAVVSGEFEVMVSRVLFHRGGRLVGHGEVFVVRAPEGTRGSVGWGDEDEDEDDPWQVKIAGGPQSRAWVRMHHHPDTMTMSFSDGATTAATTTYDEIDLRDAAAAVWLQKVERDERWFDQELSYRDGSLVYDHTFKEPVMQERAPGVVDEEALETGYVKAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7W0</accession>
    <name>A0ABR1V7W0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013143</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663149.1">
        <property type="nucleotide sequence ID" value="XM_066817457.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050517"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007300">
        <property type="entry name" value="CidB/LrgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249:SF0">
        <property type="entry name" value="PLASTIDAL GLYCOLATE_GLYCERATE TRANSLOCATOR 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249">
        <property type="entry name" value="PUTATIVE SEROTONIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04172">
        <property type="entry name" value="LrgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="488"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="169"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="55867" checksum="DCAC267016FE122B" modified="2025-10-08" version="1">MLDNAEEKLKDAVLALKLAAAASGQSSLRAWLFVPAGILAMLAACYGVDRLFQIGNVAFPASVACLVVLFLALLLSEQVLGEHRTRRLVAYIEVPGGWSLRWIGVFFTPSFVLLPLSPPIGVVEVFKMIAVFVGAVIGFLVMMVGTAYMTRGLQLAVGSSKRAITERAEEMGHETDEIPMTTPTPAGGRTPDTDSEPPHSPRPSQVHLADAATPPLPESPRCCRHQHSNDISRLARPGSAATTAGQAMGRHHCCKSRCRHLLLAVRSGRDPRLLFILTYFGSLALPPTWRQFLHPVLVSALFTVLGIWVIGLTIGRDLDSTLREYKVGANYARVWNGSHQLLGAGDMFSTVLDASIIALALPMYQYRRELKQHFLAIVIPNVVVSVASLFAYPWICFAIGITAERSLAFASRSLTLALAIPATSNLGGDANTGAAVAIMSGIVGVLIGQRFLALLRIPEDDYVTRGVTLGANSSAMATALLLRTDPRAAALSSLAMSLFGAITVLFTSIPPIANAVRSLVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9S3</accession>
    <name>A0ABR1V9S3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663461.1">
        <property type="nucleotide sequence ID" value="XM_066817769.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050829"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03457">
        <property type="entry name" value="intradiol_dioxygenase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF1">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539420" evidence="1">
        <location>
            <begin position="19"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="2">
        <location>
            <begin position="118"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="331" mass="36058" checksum="2DDBD8A312945735" modified="2025-10-08" version="1">MHFSAALIGAFAATLVAAHPGANVEEEAQERRDYLATAKRTSLDHCSAQMQVRGLGKAAALRRRAVAEKKAKRGVVARRDLADLNKSHHSDADYDATTPLDTLFAKEKSCVLAPETTEGPYYVAGEFIRQNVVEKEQGVPLTLDLAIYDVETCEPIPDTWVQIWSCNSTGIYSGVPSGADYTPAPENLKTTFLRGFQQADASGAAQFETLYPGHYSGRTQHVHVAVHPEATPRANQTILEATVSHVGQFYFDQALSDQVEKLAPYNANPQPVTTNDKDRLLLVDLETTDPIVEYVLLGDQVEDGVLAWFSFGAKVAATYYEGGGVATPKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGK8</accession>
    <name>A0ABR1VGK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664174.1">
        <property type="nucleotide sequence ID" value="XM_066814884.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047944"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="396"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="504"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="645" mass="68493" checksum="37E5EE05B716930B" modified="2025-10-08" version="1">MAGKHESASATATATATATEPSWRPFAQKLSGFMRHGTITKNRKVSPSQPVAQIGDVDRAPSVFRLGRNRSQQKSPSTESTIEFKPLEVDISKLESIRLAEGWLEQEPPPKKPDPEQLKKKPLPKPPPASSTPIADLFASKAEFDSGLQDRRRHTHLFLGSTNDTTSADAQTIARKPVPTSPAPTTTTTQTATTTTTPERQPPATHAATYSILERGRPIEPKDIIPQEPVADLADSATPTQSSIAQKRRSLQSSQSNAVPPPSAWSNASKFTPDNRHSMFASVALSTSGRIDTSATRPIQTPRSASANPVDRIQAWQKSITSAPMAPPPSNALGTPQTSAPVRKVSPKGLAGNRLAWIRELEEKKSNDLRKDVGVLKKQAGSVSNKLAMFENKSNSAAAPSSVPRLPPLSRSNSTTSRMSSVGLKSTTTWDKDNATATPRTSIDTTRSSHRNSGVMSYYDESFREKMEGLVANLAEKDDEDKTAPVPRKRRITASFVSVEGGKKAAQAMAAAGVAAAAAKSEDAAAPAADAKPEEKKEEEPVAAAQEEANKAEEAEKASETAEPAQTEEVTPEVPAEVEAEAQPEVAAAPEVAEEEKAAAEEPEVEVAAAEAVEQPAEVVVVAEPVAQDMASELAATEVPLPGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHQ4</accession>
    <name>A0ABR1VHQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664573.1">
        <property type="nucleotide sequence ID" value="XM_066815283.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048343"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="485" mass="54474" checksum="DA16D95262B9EEE1" modified="2025-10-08" version="1">MPQFMFVAVEGGTKPAKLTRSIRSHSIRTALQKSSNSAQQATSKAATKRSRITNHADETKSATFTCCDTVAAKLWPMENGTPMELLASLFLTRIDSVDGGCLDPFNSLPVPKSVQVDHLVKYFLTKFDFESSTADRTRLWFPYAMQSVSMMHSTLAMAAVVWRAEDVALEKSIQLEGMRQKYEAIREVRSQISKHVGVERSDSDMSQLMSTMSTLVFVEIYDGNFEVAELHLQGVRTLFNSHRRRSNLMADFIFCKATSMADIEVAITLGRPLMFPTLHTSQAAPPLLLLDCADKSPLDNSITESNSHEVVGIFNRLRHAILMRQSYLSHERSPLSHIIKRTHALVLAVQVFMFATLRQVPPQSKLMRRMVARLHQTVGESPVASNIWTGYESALLWIAFVGLLGTGVTEASQQGHWFLNLFRCTAGADWCADYVLCNRDIRQVFSTFLWDNAYCQPVLAELELQQGLTLLRREPDGSLTPYLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI46</accession>
    <name>A0ABR1VI46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidylinositol 3-kinase VPS34</fullName>
            <ecNumber evidence="7">2.7.1.137</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_011119</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12709"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.137"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:12710"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.137" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664724.1">
        <property type="nucleotide sequence ID" value="XM_066815434.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048494"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08397">
        <property type="entry name" value="C2_PI3K_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00870">
        <property type="entry name" value="PI3Ka_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00896">
        <property type="entry name" value="PI3Kc_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057756">
        <property type="entry name" value="PI3-kinase_type3/VPS34_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002420">
        <property type="entry name" value="PI3K-type_C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008290">
        <property type="entry name" value="PI3K_Vps34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF7">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00792">
        <property type="entry name" value="PI3K_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000587">
        <property type="entry name" value="PI3K_Vps34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00142">
        <property type="entry name" value="PI3K_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51547">
        <property type="entry name" value="C2_PI3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="C2 PI3K-type" evidence="11">
        <location>
            <begin position="12"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="PIK helical" evidence="10">
        <location>
            <begin position="342"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="609"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8070916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="893" mass="101010" checksum="94727B4587A04136" modified="2025-10-08" version="1">MDTFSFAQSVSLDYPLSIRIVNLEGDETPQKDSTLIKRPELRYIGSNTSPYSDLYVTVQVWAGSKPLTVPVQTSYKAFKNERSWNEWLDIPMPYKSLPLNSCLAITLWDVSPTGGKQAQGHAIPFGGTTLPLFDKDNQVQKGRLKCMIHRHQKADGNDGTTTPFTVPKRRQGTKKNDLATVDKERDEMDRMDKLFKKYEMNEIPKVEWLDHLVWRVSERRASEVTRISVKSLQRQGSLRQEADKSSMQDGSVGAEYDAEGGPSQFTLTIELPRFDFPLSASQSNIDIKPPPEVQFGPGINGSAGGSSRIVRIYDPEVAAKDNPAESKHRRLVRSQHRHGILDKDLRPNAKVRDELNTIMAYSPTHTLTLEEKDLVWKFRYHLTKDKRAVTKFVKSVNWQDQSESKQAIQVLAKWTEIDVDDALELLGPTFDSPAVRAYAVDRLSKADDNELMLYLLQLVQALKFEHISTDTRHPATEASSLATFLISRAVENFTLGNYFYWYLGVEWDDKSPEQGPEVRTMYAKVQYDFMRELENRPGGLETRQTMKRQAELIAVFSKISSEIQASHESSNRKLDKVKALLADPKTEMLVIEPPLPLPLDPSVMITGVVPEETRVFKSSLSPIMATFKTVSGGKYPMMFKTGDDLRQDQLVIQIITLMDQLLQKENLDLKLSPYKILATSTTAGASQFVPSQTFAHIAKKHRTNPVLAYLKQHNPDERAEMGVRKETLDAFVKSCAGYCVITYILGVGDRHNENLLLTPDGHFFHADFGFILGRDPKPFAPAVKLSKEMVDAMGGSNSDLYLQFKQYCSLAFAALRKSSNLILNLFSLMVHANIPDIKLEPDKAVLKVQERFHLDLPEEEATRLFWSIMEDSLSAYMPVVIDWLHAKTQALRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIX1</accession>
    <name>A0ABR1VIX1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664994.1">
        <property type="nucleotide sequence ID" value="XM_066815704.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048764"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="475" mass="53040" checksum="59DDE884AC81D858" modified="2025-10-08" version="1">MAEKSVNVTRTSVLEDGTLPFPIRGPKTLRIPVERDVAYAKNALRGLNLLQTRYDAAIASQSLSSALEYLYEHLPTKVSDLVTWHSPDDFDIFPADIGPDDNAAYRRFLEQHPKHCATSYKAIRQHEYFIQQVNTHDDHYVTVLLHLRKDDHPRTRFCQRVPFTTVDFSAFVDPSASSSSPSLTDPASEARVARVRARMAEFLRPVLSNIDDRAAHEGKLWVPASQPADADFSSGLRAFVLFEQFTRRLVELWCEGKSYDAETLWRPTCAYMNLEKARDDMIGAASRQVRRYMGFTPRVSLSLLKGPKNGKEDPQSFVLHRLMTPRDVGQIGDFRFEGDDEDDSGVDQSDSDDDAASEASDDSSSAARKGGPIRGLPRVDLDDSEDEEDLQQNVDDAFMRLAGADDADDEEEEEDKQHAKLASSKVSSPTMDVEMAEGPEVIVIEDGDDDAPIFWGPQWPGEIPRPASSRCAVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIX9</accession>
    <name>A0ABR1VIX9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-binding oxidoreductase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664999.1">
        <property type="nucleotide sequence ID" value="XM_066815709.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048769"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="625" mass="67837" checksum="A8FA122D0252A9EB" modified="2025-10-08" version="1">MDGIEMQSYVAQEVATNSVSPLSAPAQEPVPAIIPIAECIGELKWIHFKDPHPVRDFARWDAATRGPWGSLMLIFKHPLNILGVLGATLTIVALAIDPFAQQVMGFQSCLEPVDGALVTIPRANNYTRGDVQYSLGTPSVGGPMTAALYSGLLNPPDNASSLIPTLCPSGNCTFRNDQWGTYTTLAMCASVDDISSSIKGTGSFTSWNYSLPSGLRIMMGEVLATREAYEPPRVFELPSEDTSLFAFQALMVALDCDGNTSTPSELACRTGARAFNVSLSPCLHTYGNVTYTDGIFSETFSLAGNHPSIPGLDCSPSGQPSQQKTQPASLFANRGLYYNNHSAKASDDPETVYFDKACTYDFGYEPTAGLNRILNTVFFGNGTKGGVNRLVTPRGIGHQLVGDVWMERLWANGTADRGSLAAYMDGLTAWITATIRREEAVHDGELAGLGMVYGNQTCIVVSWGWIAFPAALVLLTVVFLALTIFESHRHTTRLGTVAAQAGRKLWKSSALPLLWAGLENDTRYRPDHCFSDVPDMEAYSEKVRVRLSKTVVYVVGPEEGSEPSTGTGSRPLLRIIPKSMSKEHHQIETFGVAHIPRLGLWLEDIASQAGAEIITEYRPHQKESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLB6</accession>
    <name>A0ABR1VLB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Patatin-like phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011294</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664899.1">
        <property type="nucleotide sequence ID" value="XM_066815609.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048669"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07216">
        <property type="entry name" value="Pat17_PNPLA8_PNPLA9_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF4">
        <property type="entry name" value="SERINE HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="21"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="455"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="25"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="272"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="477"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="506"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="578"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="643" mass="71644" checksum="A614DC25E2DA396C" modified="2025-10-08" version="1">MDSDGALKRRDTTKGPPLRILSLDGGGVRGYSMIIILQELMHRTYVEIEGKAPRRHEIPKPCDHFDLIVGTGTGGLIALMLGRLRLDLEQCKELYVRMTRMVFQTDKTIAGIPYRSTLFKASMLEQAIKEAVREHTVDEDEGNDTGSSIASPLSRTSASSKVKRHTSNASVISFSARSPTAQMARPTFRGSYGGDPDALLYDTRENRTKTAVTAMYRGTQKGGEPALLRSYDSRKEPAPEFDCTIWQAGRATSAIGLAFKPIRVGQSQFHDDGAGTFNPSPYALDEATVNEWPGREVGVFVSVGTGRRPKGTDQNSHVWYEGFMGEFADARRKLIAKIEGCEVIHEYMKKEHLMKRGVNAENYYRLNVEVGVGEFGMNEWHRLSEISTGTRRYMGRPAEQKMIQESSTKLAKIHRAKQRYERLSSVPEMIPPARHGLDQLATGCGTSWRFPNSYDSGTDRLSLPTSNPIQTPSPRSSAEHTRPIERPAERTRPATSHASPPRTHTPRSSEPNIRTAQQQTPLSTISQSPIDDDPDRLVSHAPTPAQYRHASGADKIAITSSDEYEYSRRPQGDMVPKPLSPQPPRAYRIEPPPLPPKTPLSHLEGHNRRPSMNANGPPPYPMDDDDQPPPTVNMARKPELRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTB7</accession>
    <name>A0ABR1VTB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009164</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665441.1">
        <property type="nucleotide sequence ID" value="XM_066813479.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046539"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057688">
        <property type="entry name" value="DUF7928"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408:SF3">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25550">
        <property type="entry name" value="DUF7928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="681"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="720"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="762"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="817"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="845"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7928" evidence="4">
        <location>
            <begin position="85"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="491"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="874" mass="97962" checksum="1051FF3EE305927D" modified="2025-10-08" version="1">MGLGSYFKAEKPDKKQKRPAATAGAAIPAPVGAGPSGGGVLEKSSVPGLGGNDYELQPPTPNVHSSRNSIRSARSGASSMFLDDIKHEVMVNYLYQQQCSHLWVSDGSGEVEGVLLRKWKGNYMACPQELGNSPFARACAELNVHCAMTVNSRIIKTFLSWSPDAVDVPLMNGLRIQILPTVEDLPRARKHQFAAFVASEALLVVWDDDALHLVQRAKAIESELMELVWKTGDDDDDEKKGGPGIAVTEYEIDEESGQIKPEKRPVHMLNTYLVSIVMCIVTVSLGAAWRALAIEVSVDGSYTRLALIALAPIQVFFTLFFAQVIVVLLGPPPPRLHSGNLPHLTVQCPVYKEGLQGVIAPTVKSIKQAISTYELQGGSANMFMNDDGLQLIPEEERRARIEFYADHSIGWVARPKHGENGFLRRGKFKKASNMNFALMISCKVEDKLARYQRGPEWSQADEAQAYEQSLKEVLEEDGRAWADGNVRVGDYILIIDSDTRVPADCLLDAVSEMEQSPDVGIMQFSSGVMQVVHTYFENGITFFTNLIYTAIRYTVSNGDVAPFVGHNAILRWSAIQQVSYEDEDGYEKFWSESHVSEDFDMSLRLQCAGYIIRLAAWAGEGFKEGVSLTVYDELARWEKYAYGCNELLFHPIRTWLWRGPFTPLFRRFLFSNIRFTSKITVISYIGTYYAIGAAWILTSVNYFVMGWFNGYLDKYYVDSWQVWFSIIIVFNGLGNVALAIMRYRIGERSLLYALYENFKWTIMLAIFLGGLSLHVSQALLAHMFEIDMTWGATSKEAEFSNFFIEIPKVLKKFKFSMLFSIFFIVAMVIMAQAPFIPISWRITDFVAILPMATVAVSHLLLPLALNPALMTFSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTN1</accession>
    <name>A0ABR1VTN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Muramidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665472.1">
        <property type="nucleotide sequence ID" value="XM_066813510.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046570"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="183" mass="20874" checksum="DD700E5DB2474A13" modified="2025-10-08" version="1">MSGVIRSYLTLPHRLCFESILLRAVASSEVHIQPLSLRRADTQIRSCSCVLIDRGDESKVPTSNVRHLDVPVKRWDSRDVSTRTPNTICSTYNAADKIEQHLRADGHRIWGFVVYRCTYTSDANWDLCIPRIHWAVRKEMDVYNGRDLLQDGCFQLTVITDASTLDGQARRLYVDTLKIGAHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU10</accession>
    <name>A0ABR1VU10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665627.1">
        <property type="nucleotide sequence ID" value="XM_066813665.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046725"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022047">
        <property type="entry name" value="Microcephalin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14625">
        <property type="entry name" value="MICROCEPHALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14625:SF3">
        <property type="entry name" value="MICROCEPHALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="73"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="301" mass="33061" checksum="E70AE59F7D83AFAC" modified="2025-10-08" version="1">MGTPARTPRKDLNPALLRGAVCFVDVHTTEGADASAVFVDLLTSMGARCVKTWTWNPSSPNESESSQSKIGITHVVFKDGGKRTMEKVRESGGVVQCVGVGWVLDCERENEWMDEAPYYVDTSLVPRGGQRRRKSMEPKALANRNGTLVTPMKQTSAPRDCQTVPNNHVSRRDSTAWMRTPSDRDEDEEMDAVGEEDWDAIGMLTPVPKTPAPETIARFAMDVAPETPAAQTDAEDDDSPEKDAMLMRTAPPKPSLYAGLGQGLLGREKDQGVMMRLMAARRKSLQFAPKIASPLSKAWKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUE1</accession>
    <name>A0ABR1VUE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665806.1">
        <property type="nucleotide sequence ID" value="XM_066813844.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046904"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF1">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="801"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="1067"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1224"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1416"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1502"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1249"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1272"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1291"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1502"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1582"/>
            <end position="1600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1617" mass="181020" checksum="8ABED111FE537B41" modified="2025-10-08" version="1">MSGPAPAPYWGKLPVSKVRRSSGDDYSPSHSHSRSQSLDVTSHPQPKSNRTSLQTSQTDAPTDLSYSPLASPVASTFNPSGLAPRPSSQSYAQYESPLDVADRRKRRSARNQDDLLDDTARATPPAAPDVPRAPPISYKNPYGNGRASPYTFTASGQPGPPPSALQRSMAQARATDADVDIHRGYPTERLFGATELESSYQDFDEEDELAAKRAARAANSGAKGDVIRTHSRRQSSGMAFDDPSPSKRRGSQRQPFADDRSPLQKLELTLDSITKEEKRARVEAAERRARAKAAANAAATAQPDSGRSVSQQGYQPGQQQVRFRNRRASVGQEDQRRVVVTDPVEAVPSSATKPTSSHGPSTPRSQIPVPKNRNIPASEKSDLPQRKLSFRERAAKNDANLIGEVIKPPARRRTYVEDETEDIDPMGTRGPDITAIGVNRSLSLGPDGRPPPSARPLPVPPKPATTKSVKFPDQAYGTPLHSEDNLDNPEHHRFRDFMHHEHLQPGHGLYRSPNYLDEWRKGNVGTLAGALLDITAEVPAPPEPSPSDMDPLDAPWWETKGRRRGSMSSRPKKAEAFDGEYDETQAPTRFKPPLHLKCGPLLRYCGLRHEKTPTRNNRNGTVVDKEIWRGSVMIVTQDAGSSYDIVPILRLFVQPIELLPPPPEELRDEQALRPEYVDPIAGIPKLGRKGETLYVRPVEHLEEAKDMSMLDPDDGLFESTRSAPDFDGTPDPPGSFAERRKRIQVDGEKLGKYRDVRGFRLHTERGCTFWRFNIEVELRDQQQRIAYRINRGPSLGFWVPGRGQAMNIMFHSCNGFSLSVKSDDFSGPDPMWRDVLNNHQTRPFHVMIGGGDQIYNDAIMNQTKHFKDWLMIRNPLHKHNAPFTPEMQDEVEEFYLERYSMWFSQGLFGLANSQIPMVNMYDDHDIIDGFGSYPDQFMKSPVFSGLGAVAFKYYMLFQHQSVMEEDEKTEPSWVLGCKPGPYIQELSHSLFMSLGSGMALLAVDARTERTRDEVVREDTWKKIIDRCYAEIAKGQTRHLLVLLGVPIAYPRLVWLENILTSRLMDPVKALGKAGLLGNFLNNFDGGVEVLDDLDDHWTAKNHKEERKYVIEDLQDLAADKSVRVTILSGDVHLAAVGQFYSNPKLKLAKHKDFRYMPNIISSAIVNTPPPDMMADILNKRNKVHHFDKETDEDMIPIFTTGVDGKPRNNKRMLPHRNWCAIREYVPGSTPPSTPPPEDSEYTLDATPAGSKSNIFRRLSFSSKNRGPAYRPDLPEEKDRSRPPMASGGGLFRSLSRRASLSGPEKRPGKLTRTLSLGRGDTANSKGGFFARRFSTSKKRDDGGINGSWGDDYSDEAMYDDYTPPPSQPPQQRRTRPTAMEAAGPNSDKLARMGLRGGAGHPVEFEVGDDAYFTARPPHRSHTQPVGHARDYSLSPPPMERPRPFHRTPTGLSAKQLRKNPQRFEVDVEGGLEITLNVEVNARDPAGITVPYRLLVPRLEYEYQGEDPDDEEEEAAVAAERQEEVYPYGDEGAVIDDEEDAGIEREPYQPQQPKPARRGSIKRWFSGRRSNSMSEGAGGAGAYRDHRWSEEETYGHNRPDPRQTAQAYSEYWNRPGHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVF0</accession>
    <name>A0ABR1VVF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666164.1">
        <property type="nucleotide sequence ID" value="XM_066814202.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047262"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="336" mass="37849" checksum="677B8AC79405999A" modified="2025-10-08" version="1">MKGRPIDQLVYEYMFTKPRASDPQNFHALLHRHLILEVRQEVHSFYGHLDTQEAKYPGLDYCHHIHRIRLSRWPWHRRLFRAFDGLRLTNSEISNLTKWEGTKWAKERFERDSGIIIRDTADEGMSEWVPPENRPTTATTSPNDERTAGVEAEAGDTTENADDDMEGEEDSDGEMESIGIALNQRLLERTARREAGADTSEPLDEEWEQWLKNAIDSGELPFLSGQTMQQSPTLARHQQQIPVTHVLNAARAGQWNAVPPSIREQLMRRTLASEVAAADAGMPALEPSSSTTAPRNSVPPQPTSWRRTVGNLRLPVGEASSGTSTETVRLTAQPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVK3</accession>
    <name>A0ABR1VVK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666208.1">
        <property type="nucleotide sequence ID" value="XM_066814246.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047306"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052814">
        <property type="entry name" value="Peroxisomal_DnaJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45006">
        <property type="entry name" value="DNAJ-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45006:SF1">
        <property type="entry name" value="DNAJ-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="519"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="541" mass="59120" checksum="593EDC24BA3FF6AA" modified="2025-10-08" version="1">MVADTAYYDALGVQPTATDIEIKKAYRKLAIIHHPDKNPNDPTAHEKFQNIGEAYQVLSDKDLRAAYDKYGKDASKPSEGFVDPAEFFSSIFGGEAFVDWIGEISLMKDLTATMDITMTGEEGEEAEGEAAAAEAAAASATAGESEVPGTEEAKRESAKATGDEKTAAGAAAAPAVTVEDEKSNAKAAEAAAEKRTSTEPPPAYSQAAPENPSVPPPSKSPSASGTSTPSRHAIPMRPAIMDRPSDDTHVAEQTEEEKELRKKDKKKGGLSKEQREQLAAYERERAKVREERVKTLAQKLLDRISVWTETDKGPDVTKAFQEKIRLEVENLKMESFGLDILHAIGQVYLSKGTALLKSQKFLGIGGFFSRMRDKGALVKDTWNTISSAIDAQQTMEEMARMELQGGEDWTDEKKSEYERRVTGKILTAAWRGSKFEIQSVLREVCDSVLNDKKVPLPKRLERAEALVFIAEICSKAQRSPEEEGEYMAFEQLVAEAAMKKEKDSKKKGKDKEKKHSHSGSEAEAAAAAAAAEQSNLPREKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVN4</accession>
    <name>A0ABR1VVN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666250.1">
        <property type="nucleotide sequence ID" value="XM_066814288.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047348"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="216" mass="24987" checksum="DC4B12562C35F771" modified="2025-10-08" version="1">MIEGQFESDKAIHEVSPFFCPEPLAWGKYTSTPGPDQYFLLAQFREVGQQPPEPLLFVARLADLHKRSVSPTGRFGFHTTTCHSKSPQLTDLWEDSWEVLYRKQLAHVFEQDRQKQPPWDEYDFYADLVLDKCVGRLLGPLQSEGRSIKPCLVHGNVWDGNTATDMETGKPFIFDGSAFYAHNEYELGNWRTSRHRLSDKTYIRTYKRHFPASEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWD5</accession>
    <name>A0ABR1VWD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009279</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665556.1">
        <property type="nucleotide sequence ID" value="XM_066813594.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046654"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="17"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8074616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="236" mass="26726" checksum="57D5C9BDFC113FF6" modified="2025-10-08" version="1">MADVEQPQDPTDDGKHALGDCIACGDTIWGIKKDDDERVLSCGHIYYWLCFARNVKSALGSLPFRPVRCCGQDPVPPSIIWFVQRRAEEAGFSLSDDEVTKYIFMNDEAGSGSRVYCHRRECNAYIPTEDRTDTAGWCWICEADTCLTCRQAAHGGVCDEELLERSKEADEALLRLAEEKGWTQCPACNAMTERIDGCNYMRCLCGQFFCYKCGIPEEDEGDHFHESDGEYQEYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY20</accession>
    <name>A0ABR1VY20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_010405</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666682.1">
        <property type="nucleotide sequence ID" value="XM_066814720.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047780"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03228">
        <property type="entry name" value="ABCC_MRP_Like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF15">
        <property type="entry name" value="ALPHA-FACTOR-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="743"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="786"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="863"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="889"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="966"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="21"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="345"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="746"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1081"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="596"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="678"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8075742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1362" mass="147685" checksum="C2AB1716DDDAB26F" modified="2025-10-08" version="1">MLTSIKYLFAFTDRKGYVALAAGLAASLVVGVLKTSLAVFLGEIFPIIADFGNGRITGKTALSRVSNWCIILTLAGGIAWIANFVLLLAWVAHGERQARSLRLRSFKQLLAKDLAWFDGLCEGIPAVLSGLYSHIRELQAASSVALGNLTVDIIASVASLGVALYFSWKFTLVLLSTVPIAIVVLGLLVREIEPAILAQHSALASASSYVTSTLASIDVVKVFNGLDHETWQYSDGVRRSKYFYLSQSRANACQMGFVKFWLELLFVVGFFYGTVLVQDGASVGSVVATFYATFGALQAIESCIPMYLVLVKGILAGRSLHTFLGDNERKYRPSRRLGHSEAPYIELMDVTFAYPSNPSSIVLRNVSLSLSRHRPVTFIIGRSGSGKSTVGNLLVNLYKPSSGSLRIYVDNVEIWPKESIRSYVTLVQQSTALFDQTLRTNLEWASSRQFDEPLVHPHELSEACRVASLQPVLAKLPLGLETRIGPGGHSLSGGERQRVAVARARIRDPVCLILDEITSNLDPPTRIQILENIRQWRHDKATLVITHDLSLIGDDDYVYVLEEGRVVQEGTGRDVELEDGPFTQLLNSADEYGCIKDDNTNHAGDQPDSDTSGGRHVSASSQASSLSVRSILSQIISPPISSMFWPIGGLQSSVFSPLGAGHALSNLSNRALVTFMERPPGESGGSGTKLTGSSTPAETSAIAGDDTLVHSLSEQSDDAGHIQLPLRAIYQTVWPHLRLSYRLLFIVGILCALLVAASVPAFSVIFAHLLVVLYSPEQQGPYQVQWTLLLFLVALVGGFATFLAYHLCDCAAQAWIDSLRSKALSRILIQPRAWYARPQNSPHRIAACIDLGAEEMRTLVGRFVPMMLVVVCMISTSIVWAIVISWKLALVTLAAAPVLMASTKGFALVSAKCDMRCNDAALRTHGILTEVVTKINTVKALAVERFLDREFSQSASRTLSLGIRKAVVMAVLFACWQSVLWFTMALIFYYATVLLAVNREITVGAALQVVNLLVMGLSTASHILNSVPAITAAQATASQLLHYVNLPIHPDEGRSQGDKTVISGKRSSSFGNKHITSPFPIRMDGLSFTYPPSPGLDGNNPPPKRPTLTNINLEIRPNTITAIVGPSGCGKTTLAHLLLCLYEPDPIHPARNVRPSKYRHPLSFAGLPPSMINLEALRREQLISYVPQNPTLFPGLSLHDNILYGIPEASPLRSNLAALHRAAADAGIHDFIVSLPHGYNTRIAGAGTGGIGLSGGQTQRVCLARALIRRPALLVLDEPTSALDVQAAAEVRRSLVRFAKNGGNHNNRGSTTTVTRGSFAPSLLQDPSELVDEYGTPPLFPPDSITGERGRLRWLLLHIVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZZ1</accession>
    <name>A0ABR1VZZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666439.1">
        <property type="nucleotide sequence ID" value="XM_066814477.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047537"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="341" mass="39870" checksum="A92D759CA159A711" modified="2025-10-08" version="1">MTFLWASAAQKIHADLRLCRAKVYRKCVAGWMDLRRRFWAAVHHPIDPDEDEGDPDNPGLQAICFLIKSFQIHVEFVALRRFNYWIGNAGLPAVALKREYLSPYLAGGDNYDSSASQWASNMIQRIPLELFLSACLLAVGSFLDIYVHTHEYFLNLESKKRWLNWNNKFHRDLWVISCVLITISAAIQIRAAYHVLYPMYQLLRPLCTLHLSRFLSGDSFMEGSSSIVHHWWPESVWRFAQVWSDTIWSFENRWSILTLLFVLAVVVPFVNLFINALWTFMYKSIEWIMVTARPNLHHNYTGYKTFGDYPVDFGRMLLGNWITICRSFLLRDATPSKDNHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7Z2</accession>
    <name>A0ABR1W7Z2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Vps52/Sac2 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007424</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667081.1">
        <property type="nucleotide sequence ID" value="XM_066811739.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044799"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007258">
        <property type="entry name" value="Vps52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048361">
        <property type="entry name" value="Vps52_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048319">
        <property type="entry name" value="Vps52_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190">
        <property type="entry name" value="SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190:SF7">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20655">
        <property type="entry name" value="Vps52_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04129">
        <property type="entry name" value="Vps52_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps52 coiled-coil" evidence="7">
        <location>
            <begin position="165"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Vps52 C-terminal" evidence="8">
        <location>
            <begin position="350"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8079606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="74544" checksum="24C215036372C93B" modified="2025-10-08" version="1">MWLDRLAAQATTPSTTPPGSRAYSPSPGRRTPSGLGPYVTSQQRPGLVARTSSFQSLASNVSNDSSTSSLLAYSRKANGSALKQSTTAYNGPDPVNVLQRLLGEEPETAATAKRAAESVTEDALDLDFDFGGLSLTELAHAEDYGEDGPGVHRTQTVEEYENDKTKFEDLHRSIRGCDEVLSSVETNLTSFRNDLANVSADIETLQARSTALNVRLENRKAVEKGLGPVVEEISVSPVVVSMIAESHIDEAWLKALAEVDKRATAYKKNAAGAQNSKGLQDLGPLLEKLVIKAVERIRDFLVAQVKALRSPHINAQIIQQQNFLRFKDLFSFLHRHHAQLANEISLAYQNTMRWYYLNQFTRYEAALKKLKLHNLDKTDVLGNEDTSRKGTVLGSAKISGPPHDAFNLGRRIDLLKTRDQGAISSYLAEEEKSTHYLEVTFRNFNLALIDNATSEYTFLASFFSPALSYSAINKNFTYIFDPTFALGQALTKTLITDTYDALGLLLCVRLNQHFQFELQRRKMPAADSYVNATAMLLWPRLQVVMSAHAESVRTLTSALPTKPPPKAEQAKLSAAPHVATQRFGQLVHGILALSTEAGDDEPVVTSLRRLRSEMEAFLTKYSIAFGTDKRKRERFLYNNYSLILTIISDTTGKLAEEEQEHFEGLKAAFQEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9G2</accession>
    <name>A0ABR1W9G2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aurofusarin cluster transcription factor aurR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667619.1">
        <property type="nucleotide sequence ID" value="XM_066812277.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045337"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="326" mass="36230" checksum="B4FBDC8D07BE190E" modified="2025-10-08" version="1">MKPVISDPAQSVANLADHRLSSYLERLSTHMEDAYLKYCDPKVPLHYFTLMMTRVSMCKLKVLAGFFKTAMQIPAPLSPFESEALFIEAIKLLEYDSTIHANNTLKGYFWFSALHFPFPAYICLVKDLRTRTTGELCERAWAAIFENHERRQLLRQMRSPMQLAFSPLFVKAWDAREAAESQLGRTLAPPPLITAMRQIVARMGFSAKSKSPGPVSSHPTPPSTASPSVSSVYSVPPAPASAPPAPVASQPPPPSMFPNGPDLWSNIHGPSMGGRGHYPPEFHEVNLGGEFDWQAFLSQFSNSYIPPQEMAIPVAPPDPTTQVYWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9X8</accession>
    <name>A0ABR1W9X8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Opsin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_008122</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667779.1">
        <property type="nucleotide sequence ID" value="XM_066812437.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045497"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15028">
        <property type="entry name" value="7tm_Opsin-1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF2">
        <property type="entry name" value="BACTERIORHODOPSIN _OPSIN, NOPA (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8080304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="33600" checksum="1C6DB23F00ECA756" modified="2025-10-08" version="1">MEEVLRKTTATATATPTSFPTVTPDLPTFYFTDVATDTGKRTLWVVTVFMALSSLAFYGMAMRVPVQKRLFHVLTAFITTIAFISYFAMASGDGINFHVYKEKTTKHHTAMEVYSRQVYWARYVDVSLALEVLMVFDHPLLLADLAFLAGLNGASMLVAIFADVIMVLTGLFAAFGNSDGQKWGYYTMGCAAYLVIVYQLAINGRTAISNKDTKTKTFFTMIAGYTLLLWTAYPIVWGIGDGARLMNVDAEVVCYAILDVLAKPIFGFWLLTTHDKMSRNTASIEGFWAYGLTQEGAIRVGDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA72</accession>
    <name>A0ABR1WA72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667797.1">
        <property type="nucleotide sequence ID" value="XM_066812455.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045515"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF77">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="142"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="713" mass="79114" checksum="E078D356E98027C8" modified="2025-10-08" version="1">MLSKHFKKAAEVPCEPPLPPHPYLSLQGDEIRLLTINPGSPNLESTSQISCSLQHVDLPGSQDNGVGGGVADSGRHRGYARDWPELQTAPDKGRLLKTDSWVQKQVLSKYDEKSQQSLDPDVGGCTLAHEEGLPWRHSWGDYVALSYVWGPQTPAKTILIDGLPFLVGPNLYLALEQLRRSQRIQQGFKVWIDAICINQQDIDERGQQVGRMRDIYASAWQVVSWLGGGQDDSDMAIDALRYMARLPTEPGEIEGLYRVKRGMDVRPLFITWDSYESPFRKEVFKAILGFLTRPYWRRMWILQEVAMAHPEAPVLCGGKCLSWAEIRDAAALITADEERFGRLVTGTLPSTWNFEIGQARLSERRHLSPERLWRLMTELLQVQNDQNDASFPGVTTDMLRPLLLARDAAVTQEKDRVYGILGIKAVAERVSLVPDYTLPLAVNFQRFSSALLLGGNLDLFRLVSLLDKPIYTKGSLAGLGSRVLEAAPCVHNLPSWVICWTCAALPAAHLRAAYRAGGKPTVESQSAVVISDSCLRMQGLIVDTIVSLGTCHPAEATDDYPASGSKCSNNPYGGLDETREALWRTMVGNSTAQGECPAPEEYAWLLDPRIWRDAVAGVFAHGLGLESVMKRYGSLDLCGYSLKELIFGSGRTRRPWGERYYNPTKTQREALAWAVDVLAWRRLMSTESGRLGLAPTGAVVGTGSSFFRVAMCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAV6</accession>
    <name>A0ABR1WAV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Sulfite efflux pump SSU1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008452</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668109.1">
        <property type="nucleotide sequence ID" value="XM_066812767.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045827"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09318">
        <property type="entry name" value="TDT_SSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051629">
        <property type="entry name" value="Sulfite_efflux_TDT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686:SF1">
        <property type="entry name" value="SULFITE EFFLUX PUMP SSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="45196" checksum="B7EA8FA273B5A79E" modified="2025-10-08" version="1">MTITSEPGLGSGNDSESSPPSCPEGAAPCTSKNDAGWRRIIRNFTPSWFTVTMGTGIVSILLHNLPYNTDWIRWISVGFFALNVFLMTAFTTISVARYVLYPQIWCVMIQHPTQSVFLGTFPMGLATIINMIVFVCVPAWGNWAAYLAWGLWWFDLAISLICCVSLPFLVIHLGKTNLASLTAALLLPIVPCVVAAASGGVVANVLPDPSHVQTTLIASYMSWGIGVFFSVLILAMYQVRLSNHALPPREAIVSVLLPVGPFGQGGFGIAKLTQVTRKFLSHGGGTAMAARDYDTTYTEPLGLLIEGIGACIALIMWGIGLVWLAYAVISIATTRNFPFNMGWWGFTFPLGVWVACTTELGSVLHSTFFSVTAMIGSGCVFLLWLVVAACTTKQAISGEIFFAPCLKNLSGAERLGKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB36</accession>
    <name>A0ABR1WB36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diacylglycerol kinase catalytic domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668185.1">
        <property type="nucleotide sequence ID" value="XM_066812843.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045903"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF108">
        <property type="entry name" value="DAGKC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="2">
        <location>
            <begin position="92"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="485" mass="52352" checksum="D676541D95CACF8C" modified="2025-10-08" version="1">MGRACHASLSEHGSNVAAENNTSPSGAVSVNESAIICVRPRGDVYDVLSLQEETSNDNTVSFHLSHESVTDVPESLLDKFLVKEAPEHLRAADNRKVHLVVSIRSGTGLALDFYKSVLQPLLADFGLKPAPVPGDEDDAESLHLNLVVTRDAQSIREFTACLPLGVEHTVVLMSGDGGIVESLNGKATADDDDESAPSTVQPLPLVAMLPLGTGNALFNSLHKGVYAACEAESTPSPLVLGLRTLLRGRRAPLPSFPMQEQLSPVSHLYGAIVASYGFHAQLVWESDTPEYRKHGAKRFGMVAAELLKESHAYHARVERSILPTSSDKGQEQQEQEPQPIDRPRHAYVLATLVSNLERTFTISPASRPLDGALCLVHFGPVGGERTMEIMTQAYNDGRHVGMTWTTTPENGEEKEEGVGYEQVGEVRVVTHEQDARWRKVCVDGTIVELPPQGSMTVRTESAPHLDILVDPTVISAAAASFAATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBH6</accession>
    <name>A0ABR1WBH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667852.1">
        <property type="nucleotide sequence ID" value="XM_066812510.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045570"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="153" mass="17058" checksum="32DD7B5C69522F5A" modified="2025-10-08" version="1">MNSASVAPPVDGDSNASRKSIFDDFDLILGLRLLSIGLLIASTVLHFNGDEYTTVLNILAAIILVPQVWQLKQKHDGAAAGAVDEGRPTAYQRLGPLNDAWLGAFLFMITVWAKTLPESWRNIQFMYNFRVFFVLNLIVVTHPKLTWLYAPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC57</accession>
    <name>A0ABR1WC57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668498.1">
        <property type="nucleotide sequence ID" value="XM_066813156.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046216"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="155" mass="16819" checksum="8CDFCBFFACDFDFA2" modified="2025-10-08" version="1">MLSEEASAVKQDGQELIGGLDVRVHRNHFGRQNESFMANLDLEFMRSSNESSSSPFPAMFIRAPVVDKLLLPTAAKAHDAEATPQENPHVEVLAVLPGRHASNKAAAAGELGSVSPEGAGDIIALRQGNVFGTSFHPELTDDIRIHVWWLEQILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC78</accession>
    <name>A0ABR1WC78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007546</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FMP52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667203.1">
        <property type="nucleotide sequence ID" value="XM_066811861.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044921"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097">
        <property type="entry name" value="OXIDOREDUCTASE HTATIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097:SF7">
        <property type="entry name" value="OXIDOREDUCTASE HTATIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="22850" checksum="A58BC888454FE312" modified="2025-10-08" version="1">MATAALFGCTGAVGSEILAALLAPTTSAFASVKTVSRRPPAAAPSPKLQAIQEADTVKWGGLISTLSSPPPSVVFNAVGTTRAAAGGIAEQWKIDHDLCVENAKAAKAAGVKTSMAPYCKMKNGVEDAIKELGFEHAVILKPGMIIAREKSKAWLAEKAVETMPQFARDRLGQDASVIGRAAVAAAQMVEEGKAPSKYWEIGMADILKMGREEWQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WF44</accession>
    <name>A0ABR1WF44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase I subunit RPA12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_008536</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668193.1">
        <property type="nucleotide sequence ID" value="XM_066812851.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045911"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10507">
        <property type="entry name" value="Zn-ribbon_RPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019761">
        <property type="entry name" value="DNA-dir_RNA_pol-M_15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034004">
        <property type="entry name" value="Zn_ribbon_RPA12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF14">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01030">
        <property type="entry name" value="RNA_POL_M_15KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="11">
        <location>
            <begin position="80"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8080718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="124" mass="13493" checksum="8387B6C9FF5E3272" modified="2025-10-08" version="1" fragment="single">MSAIGSLVFCTGCGNLLPASKGDEKNILTCEACGEQNKDTVFKEIVTQTKPSDFPSLLRQKLSTVQTVERHKIRTEAATNTETCEKCGGNDITFAAVQLRSADEGSTIFYTCKKCGNKYAAMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WKZ2</accession>
    <name>A0ABR1WKZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668713.1">
        <property type="nucleotide sequence ID" value="XM_066809790.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042850"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="101"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="298"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="40597" checksum="5F3C20B24BECDBFB" modified="2025-10-08" version="1">MDFKSPSHPTWRRAFGTKHNPIVHHVRAAFRRNRADTSPRLVYPALQAGYRMLALLSRASAADTIATQEQQQQQSSASSPEQAAVEAFLRARRSERDATLAAKALHPPNSRNPRPPTSAPAKARAPPRPNLAPADARKPLPGPGIRRSEPTPAPIRTRATRRETRKEADPAPRDGGRLPFLRLTKPQPALLSRVLHKKNKKRVERISAWTQFKEEDMLDAQEEDEWERELARLGLAEEKEQKKKQPSTPRGRQQMTQAKHVVSSIEGDAETYEATIREHGLQYLSDILNQEREDSVARADAMRDLIKAETALRQQEEKERRLERRRTWEGKLQLQQQQPRILGAHSRLRQSLSDHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMH5</accession>
    <name>A0ABR1WMH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669253.1">
        <property type="nucleotide sequence ID" value="XM_066810330.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043390"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="92" mass="9772" checksum="5FFA40DF0F2C5C55" modified="2025-10-08" version="1">MFSVRHTLRASTRVTIPNADALQRTPGPALRVPFRLASTTTGGTSTDLRSEKSNPAQNQKPDDKRQASEPSQTSKGSNQGNGDNAGKGKGKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNP4</accession>
    <name>A0ABR1WNP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pectate lyase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006397</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669635.1">
        <property type="nucleotide sequence ID" value="XM_066810712.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043772"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF18">
        <property type="entry name" value="PECTATE LYASE 21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046184495" evidence="5">
        <location>
            <begin position="17"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="6">
        <location>
            <begin position="56"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="342" mass="36086" checksum="78D0F860D5C591A9" modified="2025-10-08" version="1">MKPTTALVAVFGVVAASPTPTENGPLDARTIEKRASITDACNIGYCTQNGGTTGGTGGTTTTVSSLAQFTAAAESSNKMVIVVKGSISGNTKVRVKSNKSIIGASGSSMTGVGLTINKQSNVIVRNMKMSKVVAENGDILTIQNSKNVWVDHVDVSNDMDHDKDYYDGLIDVTHACEWVTISNTYLHDHWKGSLVGHSDSNGKEDTGHLHVTYANNYWENINSRAPSFRFGTGHIYNNGRAHADHGGNSNYYNKVLASGINTRMGAQLLIESSVFENSNKKAIFSDDSDSTGYAVVNDVSLGGSANSAPKGSLTSVPYSYAKLGSGSVKASVKANAGQKLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNR8</accession>
    <name>A0ABR1WNR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669688.1">
        <property type="nucleotide sequence ID" value="XM_066810765.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043825"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF8">
        <property type="entry name" value="S-TRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="7"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="96"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="235" mass="25334" checksum="A7862AECCDCF68EC" modified="2025-10-08" version="1">MAATPQHKIKLYTNHGCPWAHRAHIALAELNVPFQEELIDLSVPRTREYLAINPRGLVPSLEFDGHVVTESAVVAAFLADAYPAAGLVPASTDEGGPLARARIAFFVDTYFSKAVGHAQKAVSAYAEGPAAQEPALADFVAAVVKEIEPLLADAAPFFGGSSKLTLAEVQTGSFLLRLYAYIKHGLVPASLEAELATKAPNFDKWAKATIAHPSVTCIWDEDRIIAHSKYRFGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNU7</accession>
    <name>A0ABR1WNU7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669711.1">
        <property type="nucleotide sequence ID" value="XM_066810788.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043848"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="354" mass="32716" checksum="5588911338182763" modified="2025-10-08" version="1">MEPEPPAPALPPAPPPTEPPAPPPTLPPAPAPPPIEPEPPAPAPAPGAPGAPGAPGVPGAPGVPGEPGEPGEPAPPPTLPPAPPPTEPEPPAPAPPPTLPPAPAPPPIEPEPPAPAPAPGAPGAPPTLPPAPPPTLPPAPPPIEPEPPAPAPPPIEPEPPAPAPAPGAPGAPGVPGAPGAPGDPGEPGVPGVPAPPPTLPPAPPPIDPEPPAPPPIEPEPPAPAPGAPGAPGVPGAPESGEPGPLGEPVGASRASSTTADAARWAAANVAASASADASMGTAVSTTVSTATDLTASASANRAGTTSAGTAVSTTTDLTACTAADTTMSTAADIATSTAANATVGTAVSAATDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNV1</accession>
    <name>A0ABR1WNV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006480</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669718.1">
        <property type="nucleotide sequence ID" value="XM_066810795.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043855"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17476">
        <property type="entry name" value="MFS_Amf1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="57"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="558" mass="59728" checksum="90CA52058594DBEE" modified="2025-10-08" version="1">MIERAKYEPALGGAQDVEKAEPQENESFGEGDPPAAHTTDDDTRPTLPLSKAKSIALVATVTGAAFLNTLSIQAVVIILPTLGAELNIPDSRLQWIVSAYSLTFGCFLLLWGRIADLYGKRIIFILGSAFVAATLIANPFLPNEIAFDIFRGLQGLGAAANVPTAIGILGVTFPPGKAKNYAFSAYASGAPLGSIFGNLLGGIIASYANWKWVFGALAGISCLVAVAGVFFIPPQPPNPSTQKRNASLWTSVDWFGGFLITAGLLALLFALTEGNVVGWQTIWIYMLMVIAGLLIAIFAAWQWYLETHSNTRSPLMKVSVFKSGMFSMAMLIMMIFFAVFNDWIVYATYFFQDYQGLSPLQTTLRFIPTGVCGVFVALVVSRLISRVPTYILLIIGNISVGISCLLFAIPIPSDTSYFAFGFPAMILGVVGADITWPCLTLFTSASLPQEDQALGGALINASGQLGRSIGLAITTAAQTAIMARERGVSVEQSGKVLPWDPPSLVGLRDANWLNFALAMFCTVLVGLTFRGTGIVGKIEKPVEGRGEEATTSGDDVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNX9</accession>
    <name>A0ABR1WNX9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Glycoside hydrolase family 28 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_006484</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669722.1">
        <property type="nucleotide sequence ID" value="XM_066810799.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043859"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF8">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046694864" evidence="11">
        <location>
            <begin position="17"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8085213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="432" mass="47005" checksum="BD93DD724EB502BF" modified="2025-10-08" version="1">MLGKLLLPLLAPAVAASYVAKPQAPQDSNTCIVEPATNGSDSAPAIRDAFARCGHNADANDRGKVVFKNETYHIQSVMNTTGLRNVDVDLQGTLLWDQNIPYWLNHSLPVGYQNQSSAWLFGGENVHWDGHGYGTLDGNGQVWYDFVNGTNNYPGRPHQITVTGSRDSVFQGIRFVQSQMWTVTIIHSENILMEDIYVNSTDTKQEVGFDFSSLNTDGADTVYANNITFRRWVVDNGDDSIAMKANSTNILIEDCRFHTGLGIAIGSIGQYDGEFETIENVTARNIQILDKMRYGVYVKTWTGRSAGYPPNGGGGGLGYAANMTFQNFTLEGATGIFAVTQCTSYNDATGGCDTSEFHIRDLVLEDWHGTAVSDVVAAVQCSAARPCTGIEIRDIDIVDTVNGTAPASYLCDNVDGPKGFACTGPTWEENNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNZ6</accession>
    <name>A0ABR1WNZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669763.1">
        <property type="nucleotide sequence ID" value="XM_066810840.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043900"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035186">
        <property type="entry name" value="DUF5308"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17233">
        <property type="entry name" value="DUF5308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="161" mass="17265" checksum="15E8C1BF59ED0BAD" modified="2025-10-08" version="1">MANLPSQHPGLAVHLADRTRTPLISSARTQQQAQALSTLTHSALLVHESAMRLGLGSPQRVIVEHASNGPFLIHSFIETDTAQHDALQEMPAYVEMNPDGFNQTGQSSEIPNDGEVDEAPMLLSTMIAPTSESALEARRAAARLERVGKAIQSSWTDSGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP82</accession>
    <name>A0ABR1WP82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006621</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669859.1">
        <property type="nucleotide sequence ID" value="XM_066810936.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043996"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870:SF9">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="396"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="550"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="785"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1155"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="905"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="138"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="426"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="559"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1155"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1170"/>
            <end position="1181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1207" mass="127350" checksum="B134AF3A202FCB34" modified="2025-10-08" version="1">MSESEGFEVVQHDESVLSGEETTGTTGTGADTGAESAAETVAPASKPAVKKTANGAKPEGSTATKRPAGSATSTIRRPAASGTTAASRTSTTAAKTGSGMAKPPTRPPAGSAVKKPAGTLSSHRSQPSVSEDERRKSTLTSAAARRTSTVPSATASSPSKPARPPTAQSTTSTRRPAASATSAASPRPSTVSRASMSSTSAPSTRPAASATRTTSSTGTVADAKKRLSTAGITGTTTAARHVARPSTASSSTVAAESAKAVEDLKSQLTEKETEIEALKTQVSSSHEKISELEDKIKTTASEGTQNTGDAADKDIDELFESLEGENAKEKEALKSEVAEALEKLKIAETELEAHKSQLNGMAAPQEGNDSKVAELQAQLEAITAEKAAIAKENEGALSKVSEEHASKLQELQKSLEEQHQAAVEALKADHASELDGSKAAAADHEKALEDLKAANEALQSKVDELASSTESAGAETTSKISALEAELAELKATSEQDKAALAAAQAESEELKTKLAEATELMESTKAELAAVQAEFTTLKEDLTKAQEAAKSSGDVTEELEKLKQEHSTAITHHEAQLKSISEDYENEIESLKGEAHFKRKFQDLEVKHDELAKEHAGLTGTHSALESKLHELTGSHADLESKHKELTGTHLNFVSKYDELNGAHADKAKAQAEALEAAKTEHAAAVAALQSSQEEHQKALDALQASHAMELEAAKSGTTADKETQLAELEELKASHAKAIEISKAESEAKLAEELEKLNAAHAAALDSNKQDFESRIAELQASHAAELSAKEADGSASSEELASLKEALEKAQAEIEAAKTSHAEALEVFKKQSDEAHSAEVEKLIGMQSDALDAAKKEASGSHSDEIAALEAKHIQAIEDLTREHEGKLAAAAADLLKHQSSASEHEAAIAAAQEALSKAQSQVESLAAELSSAKEASAGELAKAKEELAGELAKAKDEADDYRGQLAEAKMMRFELEAELDAVKNQRPDTSVADTLKAELQAMKQRHDEELAKLQAASQQSTGETQKLSQELEAKHKELALLTEQHQATKQDLAVAQEEFETHKNETDAKIKKHEVDYKDIYESMTAMVEEEQKKLAAAVKEADEMNAKFVALEEEQKKLAGAIKEANDIKTRFAEMEAHLKVKDAEIAEAKAASAAKPKGGLAQSRFANSEDGTASDPSSPAGEGEEPENFSTAMASVRRTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRA1</accession>
    <name>A0ABR1WRA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006281</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669519.1">
        <property type="nucleotide sequence ID" value="XM_066810596.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043656"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044974577" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="33"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="138"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="494" mass="53782" checksum="55598D9FF802E830" modified="2025-10-08" version="1">MIGSVLSTLTLAGLAWASTDSSPYLGLHDPRLTVQTRTGTFVGDYNDTYPDVRQFKYIPYAKSTDIRGLKPPVGPLRWASPERLDDSSEVVDSTTYGPSCAQYVSAIPAVWGLNITGNLITGGVNIPTQLPSQWVHRSQRHIVVTTNYRVNIFGNPHARGLDGNGNFGRQDQRAAVEWVAENIAAFGGDPERMTLWGQSAGAIAADEYLFAFPEDPLVRAAITSSGSALISSFGSRDHEGANFTFVAKALGCDFGDANEKKELECMRRVSFQRISNFVGQYQDNSTLVDPSQPPLTFSSQPDEKWVFANYTQRYLDGKVAKIPSVIGTTAREGSALAYVPLANYTEGPSEETVVKGTLRFVCPSHESSVARDGLGLATYRYHWAGDFPNLGPVPWLGAYHYSDLYMVFGSYGIAPGEIPPLEVETSEVMQDYFLDFVTDPESLAGKGWPEYHAGAAEGGRLAQFGAHGKAVEFVTGDSVEGACHIPEVEYNTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRK5</accession>
    <name>A0ABR1WRK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670361.1">
        <property type="nucleotide sequence ID" value="XM_066811438.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044498"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="579"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="102"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="416"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="582"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="697" mass="75814" checksum="C3D774FB3BD60A95" modified="2025-10-08" version="1">MIVLASTWLEPCVGRSECGYVHESFRDQRLYDYLRIIGPFCIAATTAGQQPPFSPKNSALAQSESPTMIRLPPSSHIGSGKKPRRTTVSAHLYASTEEAGSVAWYEKKQARLRDELDNIQKRRDALDANMAGLINKIAELQGGGREEGREDDCNSCVLKPADVLADGQLQKTNRAYKMDKEMERWVQCVADKLDVSGPPADEDHAADGGSAPEMAPSKANVACTHDLQSVTSTADAALAKGTGCFRSSQHIASSHAEQVASHLSTKAAKSLVLPSYNDPWANRRRERTSERTNDRASATSTGQDPNKEHNSSRRTKSSTQLCKRWAEESTPTASLLAPLGPLRFQSMASTSVDAFHDSLVVLDGDAPGFSHAGTLNIGHEFFSIVGCANACHLPWRPLHDTGSLQHKAANTHMFGNRTTQQKPSTCQATESKSHKAPSDSPVEAAAAPASSQYIFPKTYTLRLLGVANLFWLQGYGKPHVGNSDPDAVLYAMREPLLGGRQKCRGSSDATGLLDPEGRQEFDHPCPQHRPRVPAPWELTWGNGPDSGAEFSEPRQAVLPHQPNITTLKEHYRHIYQAAAARGRGGGGGRSGSRGASRTVSLNHKQSEALMGVLAAEGSKTEAETKKQPPVRHYKVPMTTPMKPRCDNGDRALVHNIKSGHRHEAVGWGQLQLCSSRDSNSRDKRCGKGLKGRFQLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRN8</accession>
    <name>A0ABR1WRN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein BFR2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006582</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AATF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669820.1">
        <property type="nucleotide sequence ID" value="XM_066810897.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043957"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025160">
        <property type="entry name" value="AATF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039223">
        <property type="entry name" value="AATF/Bfr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012617">
        <property type="entry name" value="AATF_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15565">
        <property type="entry name" value="AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15565:SF0">
        <property type="entry name" value="PROTEIN AATF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13339">
        <property type="entry name" value="AATF-Che1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08164">
        <property type="entry name" value="TRAUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AATF leucine zipper-containing" evidence="4">
        <location>
            <begin position="20"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Apoptosis-antagonizing transcription factor C-terminal" evidence="3">
        <location>
            <begin position="208"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="324" mass="36386" checksum="72EC5C7A8F8D888D" modified="2025-10-08" version="1">MKADAKSGVTGSLVDSMQKDVAKGLAVRQQRKAFDAALNIRIRLQKAIVASNTIPTVDQSDDQNEPYEAAEAAAIKLWNAIDAFRTDMQPGAGQKRKRTVDIDDSSEDIWEKMQDMEAKAVVRRKNVLENWDEKVKKACMDPAAQQGFRNKQSKGQQNLTTWLEQKMQDPEGTERLVKRTRTPRSCAPAQVAKKVTEDPAIYDDADFYQLLLKELVDQRTADASAATGQTATLRYAAVKEAKTKKQVDTKASKGRKMRFNVHEKLQEFMAPEDRRQWEPSAIDRLFGTLFGQQVENVLDEDAVSEDEEMGGVTAEEAGLRLFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRS7</accession>
    <name>A0ABR1WRS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669969.1">
        <property type="nucleotide sequence ID" value="XM_066811046.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044106"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF8">
        <property type="entry name" value="ACID PHOSPHATASE PHOA (AFU_ORTHOLOGUE AFUA_1G03570)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="328" mass="35706" checksum="77DD0ACA763A075C" modified="2025-10-08" version="1">MGNGQSTSVAPVAPGPTMYTATATASVAAARATALTLSPTSNVRGKTFDRFVQIWLENTDFDMAAGDPSLSFLATQGITLTNYHAVTHPSQPNYVAAAGGSTFKVIGDGFYRIGADTKTVVDLLDGKNVSWSVYQEDMPYSGFEGNWKNQKNGANDYVRKHKYVLSYQNLSLPVGRKLTDANSPLMSYDSVTSDPNRLAKSKNLTMFYSDLAADKLPQWMFITPNMTSDGHDTSVTTAGLWTRNFLTPLLANPKFNTDRTLVVVTFDETESYVSSNKVFTLLLGGAVKGKEGTKVDTKFDHYSGLKTVEENWGLGDLGENDVKAVAYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRT9</accession>
    <name>A0ABR1WRT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670014.1">
        <property type="nucleotide sequence ID" value="XM_066811091.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044151"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="112" mass="12393" checksum="1203733F9543E431" modified="2025-10-08" version="1">MIVAPDVLMHQSLNADSEYRFRQAARQLETEVEWMTRFILKHQLRVRFHAIPKGMGDCRSGRLLVQSSDDGTGDDGISLAIVSMNSTDALPSRGESPGDDIRLTMGSCSPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS23</accession>
    <name>A0ABR1WS23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Beta-mannosidase B</fullName>
            <ecNumber evidence="5">3.2.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Mannanase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_007107</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; N-glycan degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670345.1">
        <property type="nucleotide sequence ID" value="XM_066811422.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044482"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050887">
        <property type="entry name" value="Beta-mannosidase_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041447">
        <property type="entry name" value="Mannosidase_ig"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730:SF1">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17786">
        <property type="entry name" value="Mannosidase_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="18">
        <location>
            <begin position="17"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="15">
        <location>
            <begin position="199"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Mannosidase Ig/CBM-like" evidence="17">
        <location>
            <begin position="720"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase Ig-fold" evidence="16">
        <location>
            <begin position="830"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00041069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00041614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF17786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8085836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="898" mass="102602" checksum="EB876EA80B40BB74" modified="2025-10-08" version="1">MSNTKAIPFNSTPLRGWSFKQGARSSDAEWLEAGDPPTEIHRDLERHGKAPDYRQDLNELAVRWIGDETWTYRTAFRRPEESQEGLGVKAVLNFEGLDTFASVYLNDELVLASDNMFIQHRVEVALKEENELEIVFESARLKGLELVKQHPEHRFIVHQTEISRGPVRKAQYHWGWDWGPIIMTCGPTKPVALETYTCRLEGLRVVYELLDDLNEVKGKVQVECEGVEGELYVELVNNQTGKVEWSTTELQQIRSQTGRATSLYRAPFKLEDAVQLWWPRGYGPQSLYTVNAIVRSGPHILHRITQTTGFRHVELVQAPDSHGQSFYFRINHVDIFVGGSCWIPLDNDPSRHHSSESSSSYADWIRLAAEGNQTMVRVWGGGVYEPAAFYAAADALGVLVWQDFMFACANYPAHPAYLASVELEARQNVRWLRHHPSIVIWAGNNEDYQIVERYGLQYDPTDDDDKTNPEKWLETDFPARYIYEHLLPKVIESEKVGVPYHPSSPFGNGKSTVLKVDPTIGDVHQWNVWHGTMEPYQKLSEMGGRFVSEFGMEAYPHLETLEKCITRKEDRYPGSMAMDFRNKAIGHSRRLVSYVTENFRLRQDLEGFAHLTQVVQADAVGGAYKAWRRQWGTKGHRKCGGVLVWQLNDCWPTVSWAVVDYHGVPKPAYYAIKRAMQPIAVGVQRRFRDWTVKPADGELWQRDTSHIDMRRLWEDDVRFDAWVSGNGQKGVWMGRLTVKFISVKTGKQVAEPIEVGISSQTNDCIQLINDARVQSKCIKQDSREPYNPSQSDPFVIYARLHTADDQLISSDCSWPDPIKYLDFSADRGVNIAYSEDKSTAVVTAEKPVKCFVFSEVAELAGPLSDNGFDIMPGEKYEVKTTSGFPMDRLKWRYVDMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS35</accession>
    <name>A0ABR1WS35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007152</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670390.1">
        <property type="nucleotide sequence ID" value="XM_066811467.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044527"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="454" mass="50280" checksum="08D70B641F0DF7B9" modified="2025-10-08" version="1">MNFGPNKIRSVAVIGAGASGIITAAALKAEDCFERIVVFERRDTPGGTWNYDANPQPSLPIRPGLLPPAVDKPLEIPDSLPRETTHDTRERYFKTPIYDALTHVLLGCALRLRAFSAALGASAVPGDVLCAAPARSPACRQHHGRRPVPGVFGRSIGEVEAHPSQYPGRVVHSKYFRSASVYRSKKVLVIGNSASGHDITNEVATVARAPVYQSRRHKNRWDGDAPPVGIAWKPVITEYRPENGQILFADGSCLDDDDVDTVIYCTGYRPSFPFWNAAANGRELYDYNDNKLVGNYWHTFFPDYPNLAVVGMPRTLTFRSFEYQAVAIARLWAVRASTPLPTSHEQRRWEKERLEAVRREGTGFHDVGRQGEHGGDMLEYFRKLYEIAGLGTLRGKGRVPPVLSDEVMWALDHLMKYPTPGKGKDGDKAASADAGDEGWVVVDRAEKDWLVTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WSB8</accession>
    <name>A0ABR1WSB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670357.1">
        <property type="nucleotide sequence ID" value="XM_066811434.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044494"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="393" mass="45033" checksum="A219DB0C6BC34D8A" modified="2025-10-08" version="1">MVAKDAINRHYKFGQDIEVIKQQPKDWRYYAELESCPWMDPDTSEILRDPTQEELVVYMRGQAEAYHLGQLRRSNTRQFPGAMLTPPFPLNGAPTGMCRRNAESCCNKSVALYTIGHDPMPILTYLYRKWLRPFKDPVEFGQFIAKIIEIDLGQCRRTISRPKSVEKVRGVVQDILNIHRQVLHDIEEVCTADEDYYDILPLFKSMIIVTKQLPTGVHEDLSQMQVYLILTGNVEGLSAPISFDSLYAKDQDLSIGGACGPQPDMVLTTLEAAVEFVQEVERREQSVFGIWPDPDTVPPDPVPAGMDLLRKAGWTGKDLLEPSHLWVDTAQWPFWFGGGKHVYTRMLEDEDPSLTTSRMRIRQMYDPARFQSDTGRGDEWLKKRPKTRRARGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWP3</accession>
    <name>A0ABR1WWP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fucose-specific lectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670474.1">
        <property type="nucleotide sequence ID" value="XM_066806856.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039916"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.70">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89372">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="53503" checksum="58C76CE96BDF8997" modified="2025-10-08" version="1" fragment="single">MSNSHNLHDAARPTATDSQQLHYHQQQEQPGLEVDSRADTAGLHLHRDVEAEDTTKQAVEPGANGGYFPDEHYAAPGLQAAPAPAYLTTSDGKYENGRGLHPATATAGGGGGGGATYPAEAEATAPIPGTKKPNRRRLWIILGVIAAILIIIGAVLGGVLGSRAASSSSSDPSSQASGDGDGDTAAGNSGNDTAPPSAPLQYIRPGSSLAATGWRDGPDFHIRLFYQGPDQLLRYSNFSSKEDGGWGARRPVLLDQMEYKAAVNTSLAAATSVESREIVRFRYFHFQLRLLSTALKGEDKLFYLDTTNTIRLQLFRPDVRAAGNGGQLNKYPVKAAPGSRLGAYWPSLLSQDEGVGGRLRWTRYWGVNQQNKPFWEDQDANVTASAGSGLVVVPASSKYGNSGGFLFRRGMGSCDLTKNLNGLTIPDDSPLAAFTVARSGDNPQNFVNTYILYVGPKGAVNMVWQDDENSGWKGPVQYPEAFGGADAGTDIACVTPAAWAGSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXE9</accession>
    <name>A0ABR1WXE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670724.1">
        <property type="nucleotide sequence ID" value="XM_066807106.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040166"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF260">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="464" mass="51164" checksum="D8A09BFAD1C60B23" modified="2025-10-08" version="1">MAADKHTNPLLPVANPTLSYWRSEPHRLDSHRSTVQLPETCDVAIIGAGLSGVSVAYSLSSPAAQDPNDTGAPPPSIALLEARQVCSGATGRNGGHVKLKTASVLSIIEEHGLEAAEQFAALVRAQIDALKGVVETEQLDCEFELRRSYDVFLHADEAREMEAKWRECLQRGDKWTREHDFVGEKFAERVTSVKGARAAFSGPACSLWPYKLLTQLLEKAMERNPRLNLQTETPVLSVEAVDEGKSGTVIYTDRGSIRAKKVVFATNAYTAGLLPQYQGVINPYRGTASHLAPPKDAEQVFPHLSHTYNIEYGLQYPVTSTVDYLNPRPDGGIVMGGGRWLFQEPRGLWQNNIDDSVLIEPVLDASYFEGYMQRVFRGWESSGTELDKVWTGIMAATKDGMPHVGKVPQRENQWVIAAFNGGGMTQILILGKAIADMVKNGKPFEEIDAIVPRLFQTTLKRMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXR1</accession>
    <name>A0ABR1WXR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670838.1">
        <property type="nucleotide sequence ID" value="XM_066807220.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040280"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07713">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041712">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052926">
        <property type="entry name" value="Metallo-beta-lactamase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13754">
        <property type="entry name" value="METALLO-BETA-LACTAMASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13754:SF13">
        <property type="entry name" value="METALLO-BETA-LACTAMASE SUPERFAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G07630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="60"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="243" mass="26499" checksum="E8FD4B9B9F266E58" modified="2025-10-08" version="1">MNSSSSNALVEVDSLIIQAIVNDEIDQISPSPHPGMRMDTFCCGAHGLSLLITAIKAGRPSRSLLFDAGPEGEVWERNAQRLGLDVGAIEHVVLSHWHRDHSGGLVSAVRMISEAAATAKKVTTTSSAVVVDVHPDRPAFRGVMIPEPQEPISLQADPTVRELLDAGAAVRSEDGVHTVLDDMFLVSGEIPREADYEGGIRGGITFNESSGKWEQDEPIMDERDAGTYGSYLWWDEIRTHLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY89</accession>
    <name>A0ABR1WY89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HSP20-like chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003092</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671025.1">
        <property type="nucleotide sequence ID" value="XM_066807407.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040467"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="45"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="92"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="225" mass="24850" checksum="DE2AF850D906DC44" modified="2025-10-08" version="1">MSLFGPRFYSAPEPNFSGLFRLIDDFDKYSSQNGPEGAASRLGRHHIPTFTPKFDLKETDSAYELHGELPGIEKKNVHIEFTDPQTIVIRGKVERSHTEGNPPAGLLEGDNSMTGAITEGGEKNGEARRNSHQPTVEDEPEAGSTGAQSTPATTVAETVKSEQQQQQKPKAKYWVSERSIGEFSRTFNFPTRVETEEVQASLNNGVLAVNVPKAKKHESRRITIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYQ6</accession>
    <name>A0ABR1WYQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003262</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671195.1">
        <property type="nucleotide sequence ID" value="XM_066807577.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040637"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024119">
        <property type="entry name" value="TF_DEAF-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10237">
        <property type="entry name" value="DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10237:SF15">
        <property type="entry name" value="LD37257P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="1143"/>
            <end position="1185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1186" mass="129812" checksum="119CEBFC08A73167" modified="2025-10-08" version="1">MRVPTIASYISQFYPIGNTPAVCLSRGLPQGVDADILLLGSGDLRNILYTTYANLPRKLNFTCCDIETAVAGRNVLLLSLIIDENDSSNSSILWNIYYDIYLTKAAAAVLEGQLEKLLAVSDSLETWRQSKYGEALSFCDEGTLALAREFWSKCLASARALDKPALEKELKRTRQLEAGGEGSLMLTGFRSASPGAVNALQVLPETHAHYWRTGSLTEPTADLPNPLMGSILSEHTLLHRATDPVLGFHLATAFSKIAPGSPLRIDGQSQGKDRLVQAAITQFREWVGAFQSQLKHGVDVSFAIADALNFCQALKDARGGISSTPTLYRRQFDMSGFDLDPKRYSSSTVKGLLFDVVDTSNLADHLGAVNLLISASPLLKPVASSTLYVETLMKGANHRQAELDELLLGHAPMVSLILGVSAVESWTNATTTSAVDSIVIGAVYKQGNESHHHSRIAWKRGSSLSMSNGSAPMLYVEPDAMSSVFFGIYHRMFENEDPYGFMGASQDQMLAAMRKSAYPRFHRGSLAALLKHARTTFDTDWPLVYRSLINKIRDDRKMLLGSVYVQDLTLNMHSMGLFTDTWLQNDIRPNPGAEDFSAWSDIPAAVAVTLVVPRALFDKIYYADPTKRSAPTLQVGLSSSTPGQWQNFFADVQLAFGSVEPQGHPKEDSFQASVNPDSRGWGGNSNIIASAMLPTAALQVEPGSAKISLRIQTTAQSIATFRSAGLGPELVVYETNMADAAHVFVTKSLPGLSPLTPNLDSQLHPPSGSTPRLQITANVDANSARLLSLTGHVDITTDQGKKLLEDKVPIELRQTSPFAIDIVFGKDKLVLAVVFPVPVDQETSKTRIARKSAYVEAIAPLADPLKSKALASYLYPTILGPDAIPITLNGQNLSLDRLPILDVDPKHKRDNQWLATLASHVFSLKEKRLRESGKTQEGVNKDLRVNFKESVFTMFMLASGLQGGQTGLFSLNQPDKGIVLLIFIRCIRIDAAAGSVVADAAIMPLTLDTVLSRKLEDFFLLLRELEICAITVNDEELRLWKQVLPDMVERCRTWSHTADCEYKKPGAGIPLTFETGKQLLCSCGNGKLPENYMNIPGWDLASRYAVRAAISLSFSVPFIEDIVNTDTLNFNQGMQDMAISEKCRSCGKTKTATGGKLMQCARCKEVAYCSKECQKADWKKHRQECA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ03</accession>
    <name>A0ABR1WZ03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671296.1">
        <property type="nucleotide sequence ID" value="XM_066807678.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040738"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="276" mass="30145" checksum="52F8D60A23910962" modified="2025-10-08" version="1">MSMEGIENPALISEAPEPTSYVRPRAPLVLMHDGGGTTFSYHLLDPPANRALYGIANAHFDDGGWWHGGLPEMAAHYIGLLSEALPEGGDVVLGGWSLGGMLALEMAHQIATQPTGDGSADRRPRFNVVGMVWVDSQCPRPASEVAALAEKQLPEEVVRRPREELEGMKLLDKVGLNMLNARIMLQSWEKPKWERDAVPPTVLLRARESYADPASSFVDYQRGHRMLGWEAYSKEHGDFFAGGGGCGGSHFSLFEDDNIIAISEKINAAADKVDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0B9</accession>
    <name>A0ABR1X0B9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003775</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671708.1">
        <property type="nucleotide sequence ID" value="XM_066808090.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041150"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="3">
        <location>
            <begin position="677"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="419"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="476"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="531"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="727" mass="76738" checksum="4F4C6FC0648A2EE5" modified="2025-10-08" version="1">MDTTSLQTPTTGRSRFSKALPAPPPGLHDGLHKSIPNTASTPGPFKIPRKLPSLPQLPPTTPPPTTTRTTTAAAFPPRKSSVGARLNLTNVIPPLPALPPLQKQLPTTPKKMNAIPRKAVGQQPAATTAASAVPELAPQGKDASTPRKLKRMSSISSILSAYSSASNGSQDSAHRSSQGSVATKDSEPSLSPERNPHEDELPDTNDQMENGQMENGQQKSLPPVPAMDTRRGGSPTLGLPANPRGGLPATPRSAKAVGGEAPSSTTPAPANSRNTPLTAPATPRKTPPLPKPDSLETTSSTPYAPTSLQNTPSSTKPYNLEAASSSPSAAANDTQPLWQRRASKSDASIKVPDLTLTVSHGSTGPPVPPKSEASSTRPSPLPPTSSSGLPGRNIRPAPPPPTRILASNKPDEDGEMKRLAASVKAVAKRVAGSDAPKEEASKASAPSPIAGPSPGSAPAHDGSMQKGGLVEKRSQDFVSPLSSPEVRPSSQRGQQGAFQTAGRPSTAQNSDSRDQASQPQMPRDGQSMPHQRRDMSRSHEQQPASSPMGSNVSHQRSHEQLDQQSKAPAKETASATVDELSPASTGQTPRRQLAPNGAPAPRTRPSLSMVGEEVSFTEPRPLTDGQQSDLMSAIMLFRRHDKPIADEYPVINAAPLRPCHLKCLNDHQGFLRTKNASHSIACATCHVEDREPRFVCTTCSVRVCSRCRDLLEKHRDTHTVLSLLQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0L7</accession>
    <name>A0ABR1X0L7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003914</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671847.1">
        <property type="nucleotide sequence ID" value="XM_066808229.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041289"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044984815" description="Carboxylic ester hydrolase" evidence="10">
        <location>
            <begin position="24"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="497" mass="53586" checksum="BEABACB9E8C6EA21" modified="2025-10-08" version="1">MRIFASNKLFFLGALARLVRCTADKCASFGAGLSIPDTKVIACSHEANGTVLPLPSTVASCGGPNLTAIITTDLCRVVLLVATSSSSEVQLEAWLPDPDAWNTRLLATGTGGIGGCIDYPTMQNGAGLGFASFGMNAGHNGSTGFDFFLNKPEVLNDFGYRSLHVEASVGRQVAEQYYASSSFKKYYAGCSTGGRQGFQNAHLYPDDFDGLLLGSPGVNWLRIVASKGILTHRIGWPNLDSPAYAAGPLDGVADGIIDEPTRHRFDPQTLACGTGLLNATLCLTPQQVSSVRTAYEPITDSGGHIVYPAFELGASTNVFSANQQNGTAKMSYTILQDFWRGAVYNDSTWTPENFSTADMDFALAANPGQVNAWDTDLSEFHGRGGKIISYHGRSDETVTSALSEWFYSDVQSNTNLTLEETRAFYRLFFIPGMHHCGGGPGAWSIGNAQKYPYDQSLLDPSHNTLLALIDWVENDKTPETLIGTKYQDDVRTVLILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1C6</accession>
    <name>A0ABR1X1C6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydantoinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004154</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672087.1">
        <property type="nucleotide sequence ID" value="XM_066808469.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041529"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1610.10">
        <property type="entry name" value="CV3147-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010318">
        <property type="entry name" value="S-Me-THD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027479">
        <property type="entry name" value="S-Me-THD_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF10">
        <property type="entry name" value="HYDANTOINASE_OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06032">
        <property type="entry name" value="S-Me-THD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160991">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="2">
        <location>
            <begin position="8"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="1">
        <location>
            <begin position="210"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD N-terminal" evidence="3">
        <location>
            <begin position="600"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="751" mass="79865" checksum="A9385012C1174641" modified="2025-10-08" version="1">MTATKTLRIGVDVGGTNTDGVILDPARASEPDKGILASHKAPTTANPGRGIAHALAALFARAQPPVRPEQVASVSIGTTHFVNAVVERDPARLSKVAVLRLCGPFAKHATPCIDWPADMRDLVLGYHARLQGGLEVDGHLIADIDPAEICAQCAVIRECGIRSVVVGGVFSPIDTVERQEERAAEIVQAEIPGCDVVLSKQVANLGFIERENAAILNASILSFARRTIRSFQEPVRALGLKCPVFITQNDGSILSGEMASKLPIRTFSSGPTNSMRGAAFLVQGELDENIMVVDIGGTTTDVGLLLANGFPRQQAAYSDLAGVRMNFSCPDIKSIGLGGGSIVRHNGSMTVGPDSVGYKLTEEALVFGGKTLTATDCTAVADPSLELGQRGLAEGAVTETEISQFKAIVTHKLEKIIDKMKTSPDDLPVLLVGGGAIIAPDQLKGASRVMKPKYAEVANAVGAAMARVSAVVDTVKSTESKTAEQLLDEICSDAIERTVDAGALRSTVKVVEKESFPLQEKYIEQKTRFIVRAAGDCDFARAHLGSMQAVEEQISEMDNNMDEYEKSTRPTSDRTAEKKEVDISTYRPHVRNRVWYVSETDVEWIATGCYILGTGGGGSPYAHMVRLRQMIRDGAVVRVVSPDDLPDDAQVGCGGGAGSPTVGIEKLEGDAMLQAQEALYKVCPDRRATHMISVEIGGGNGLQSMVLGASGPGGMDLPAVDGDWMGRALPTKWQTTPVVFNERSPSGRPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1H0</accession>
    <name>A0ABR1X1H0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672181.1">
        <property type="nucleotide sequence ID" value="XM_066808563.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041623"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051714">
        <property type="entry name" value="Znf_CCHC_NABP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23002">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="178"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="194" mass="19616" checksum="815FA921D2673F6D" modified="2025-10-08" version="1">MDFGAPQGGRACFNCGQTTHQARDCPTRGAAKCYNCGNEGHISRDCPEGPKDSSAKSCYRCGQTGHISRDCPTNAGSGGQGGQGGATECYKCGKIGHIARNCPDSFGAGGGGYSGGGYGGQGGYGGGGAGGGKTCYSCGGYGHMSRECVNGSKCYNCGENGHFSRDCPKESSGGEKICYKCQQPGHVQAACPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1L8</accession>
    <name>A0ABR1X1L8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004221</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672154.1">
        <property type="nucleotide sequence ID" value="XM_066808536.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041596"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF56">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0045">Antibiotic biosynthesis</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="3">
        <location>
            <begin position="47"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="400" mass="44598" checksum="41FB4E59CB83733F" modified="2025-10-08" version="1">MAIAAPEGPQAWKAEDVRKDTTWILRLTPDEVEGFRIAMEHAHKASKPLLDMEQADFPLPDASRRALERAVATTQGRWGMCLVKGFPTDEWTEPDLRVAYWGMGLYMGVARPQNRASEVINDVRDAGGSYKAPGGRGYNTNAGLDFHQDSCDVVALLCRRTAKSGGTSMVMSSIALRDRVRELRPDLLPVLEDGEAWFHSFQGTQEPSSQPPFYRCPIFGGGQKVAAGSSSEELLFCARTNRKNTVAAQRDFADEVLRLTRPQEEALDLLDEIMPSDAYCYSMELERGDMQLLNSFVTLHSRTGFEDHDDGDPDAKRHLLRLWLSIPTSQALPAAWAEYWGDVRAGAVRGGVRGSSVTEEFKTYERRQADVMGMHFRPWEPVVTKDDMAEILAKRAAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X279</accession>
    <name>A0ABR1X279_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RhoGAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004450</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672383.1">
        <property type="nucleotide sequence ID" value="XM_066808765.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041825"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09391">
        <property type="entry name" value="LIM1_Lrg1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09392">
        <property type="entry name" value="LIM2_Lrg1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215:SF10">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="88"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="152"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="477"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="9">
        <location>
            <begin position="841"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="572"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="719"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1098"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="632"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="752"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1165"/>
            <end position="1194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1194" mass="133471" checksum="FC08E39DA52FF90E" modified="2025-10-08" version="1">MGSDYGGGLAGDRIHGHPPPPVNVNDNGYQLDRDRLHMTPSPSYQNGAFPPPTRPPGSPALSVGSESRKSNERNRSRGRDRKASGQMRICHKCGEPLTGQFVRALDGTFHLDCFKCRDCGQIVASKFFPAEDEEGGGQYPLCETDYFRRLGLLCHQCGGALRGSYITALDRKYHVEHFTCSLCSTVFGAQDSYYEHDGNVYCHYHYSTQFAQRCNGCHTAILKQFVEIFRNGQNQHWHPECYMIHKFWNVRLTPAQDGGEPLPEPEDTAESRELVKVEEEKMEDKVYRIWSVLSTFEESSAACISDMLLHVSNGAYIDGVMVAKKFILHVEVLFTAADRLDDSMKRFELKGALPLDVDAGKSQADPSTGLSYGREAKLLCKKIVSFFSLLSKTQDTGVRKLGVTQELLSLVTGLAHYLKLLIRICLQGALKFEREQHTPDGLYQFLEDLSLIETAKSEDSTLQITNGIARLSANDSDQCTLCRKPIEDQCALSGDKRWHATCVSCEKCSKELSKILDQARVQRDLKILCADCDAQSGSMGQRVEHISKLQQYVFLLRVALARLLEILRNNGALSHTPEDPNAGEYNSADGQKPPTESSPAPMLTSDSRSKSFAGGESERHQRESSYESTLNDVRRLRSTRLDKHLSSSLRKARTSRIMDGPEGQGVRPGSAGADMMSRSRDIPEEEREGGLGGSTEQYFGHQDALTLDDIPRIVAVEQAKEKQTAQNRQSRQELFRSPATHPVFGAGGHQRSQSDGRDDPRLQAEPSPQRGTGKFFSELSGLEYFIVRHVAVLSMHPLLEPEFTLEDLLSLIEARKPPTFWNKFGKAFGNKENKKNGVFGVPLEVITERDGADSTDGVGPGALRIPAIVEDTITALKNKDLSVEGVFRKNGNIKKLTEMVNAVDRDGCDAIRWNDETPHQLAALLKRYLRELPDPLMTQKLYRVWTAATKIKDADKRRHCLHLICCLLPQLNRDSLEVLFNFLKWTATFHQVDEDTGSRMDVHNLARVMAPNILYIVSKNPTFSDEPMTAVACVEEMIQYNDEMCMVPDELMDILGDSTLFSNSTDITTKEILKRIGDRSVGGPRHYDAELVNRQDNIRPMATRVDTDPGTWHNERSVPVQEPSIPFPQNQGTPPQRYRVPDHGPSPYPEQYGPAEQRPEGAENGQRQQWRNSNSQANPAAWGRQNSSIPTGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X285</accession>
    <name>A0ABR1X285_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dynamin central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004494</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672427.1">
        <property type="nucleotide sequence ID" value="XM_066808809.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041869"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF235">
        <property type="entry name" value="DYNAMIN-RELATED PROTEIN DNM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="27"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="709"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="539"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="595"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="648"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="796" mass="87947" checksum="ECBC23173152B598" modified="2025-10-08" version="1">MASLGDDLLRVVNQLQDLVFNTIGSDSLDLPQIVVVGSQSAGKSSVLENIVGRDFLPRGSGIVTRRPLILQLINVDEDESEPDTNAAYRNASAARRSEWAEFHHIPGRRFTDFGDVKREIESETSRVAGNNKGINRQPINLKVYSPYVLNLTLVDLPGLTKVPIGDQPADIEKQTRTLISEFIAKPNSIILAVSPANVDIVNSEALKLARHVDPLGRRTVGVLTKVDLMDHGTNALDILSGRVYPLKLGFIGVVNRSQHDIQGNKPMEEALKAENEFFRHHPAYRNIATRCGTHFLAKTLNQTLMTHIRERLPDIKARLNTLMGQTQQELASYGDMHFSGKEHRGSMILQLMTKFASGFISSIDGTSTEISTKELSGGARIYYIFNSVFGSALETIDPTSNLSALDIRTAIRNSTGPRPSLFVPEMAFDLLVKPQIKLLEIPSQRCVELVYEELIKICHTCGSTELSRYPRLQAKLIEVVSDLLRERLGPASSYVESLISIQRAYINTNHPNFLGAAAAMSHVVSNKQDKERKRLIQEERERRERRRMKELGEANGAETPDDNEDAGTEKGEAGPARKQIAKGSRSMSPAVRENGTGSLTAAVNGRSASPSRPGPGGARDTFLTYFFGKDGASPPGGAGAPSSLPRHVSQSVEPSFSQSIRSREEKHRPALSSSLIREPETPITGEFGAVTPFSENTEPALTDREAMETELIRALISSYFNIVRESIADQVPKAVMHLLVNHSKDVVQNRLVSELYKEALFEELLYEDDAVKKEREKCEKLLQTYREAAKIIGEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2N4</accession>
    <name>A0ABR1X2N4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like modifier-activating enzyme ATG7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004639</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672572.1">
        <property type="nucleotide sequence ID" value="XM_066808954.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042014"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.100">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.70">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032197">
        <property type="entry name" value="Atg7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042522">
        <property type="entry name" value="Atg7_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042523">
        <property type="entry name" value="Atg7_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF3">
        <property type="entry name" value="UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16420">
        <property type="entry name" value="ATG7_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like modifier-activating enzyme Atg7 N-terminal" evidence="3">
        <location>
            <begin position="15"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like modifier-activating enzyme Atg7 N-terminal" evidence="3">
        <location>
            <begin position="140"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="2">
        <location>
            <begin position="354"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="669" mass="74337" checksum="09A877F0A666A126" modified="2025-10-08" version="1">MAGPSGATPPAATDLKFVPFSSEIELPFYSALFSSKLEHDKLDESARQVLGVYEPQLGIAPEDSAKMQVLGNALTSRSVGLNAVRAEGIIRNKNTMEAFKNADRAEMIQNAGRQIWEAIKDGTIYSVPSLLSSYWKRSGSIGRFTPDESSQLVERIGTWRYSADDREYGFFLAKKVRGGEARSSLDLQEDDLGFKWDVASLGEFEKGFFKGIPEEDQYVAFVDPSTYEENPGWPLRNLLMLIRERFRLSKVQILCYRDMQSRRHEARSIVLPLSMDAAEVTELTEMPKVTGWERNHAGKLGWRSVSLAESIDPTRIADQSVDLNLKLMKWRIAPRSASRSHQRDEMSPPWRRYVSRLLQGWGVRKISFVDYGAVSYSNPVRQPLFNFQDCLNGGAPKALRAAEALKEIYPGVESEGHVLSVPMLGHPVTEKTRGDFEKLRSLIEEHDAIFLLMDSRESRWLPTVMAKAAGKLVMNAALGFDTYVVMRHGAEPRDGSDGTLGCYFCNDVVAPGDSQKDLTLDQQCTVTRPGVAATASALLVELFTSVLEHPLGAHAPAPVPKDASGTTYERDPPNHALGLVPHQIRGYLADFSQIKVRGVSYPSCSACSKPILSAYRDGDGWEFLKRALDDKQYVTELSGLAEVQRKALDWDDSEEEEDGAAGDDEAIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3W4</accession>
    <name>A0ABR1X3W4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Gluconokinase</fullName>
            <ecNumber evidence="3 9">2.7.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_005063</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>D-gluconate + ATP = 6-phospho-D-gluconate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19433"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18391"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate acid metabolism; D-gluconate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the gluconokinase GntK/GntV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.12" evidence="3 9"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672996.1">
        <property type="nucleotide sequence ID" value="XM_066809378.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042438"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02021">
        <property type="entry name" value="GntK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006001">
        <property type="entry name" value="Therm_gnt_kin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01313">
        <property type="entry name" value="therm_gnt_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442">
        <property type="entry name" value="GLUCONOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442:SF3">
        <property type="entry name" value="GLUCONOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13671">
        <property type="entry name" value="AAA_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8090102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="235" mass="25990" checksum="6025992E13279293" modified="2025-10-08" version="1">MLSYDHKISSLNGAPTPTHPNMASNMNSLGPDPKPLNTIMTPNVSNAASNGQPAPRHHHIWLVTGPAGCGKSTVAEHIAETLSVPYIEGDEFHPPANVEKMRNGIPLTDADRWDWLTLLREESLRQLAKGNESVVLTCSALKRKYRDVIRVAPYYSHDVLLHFIYLHAPADVLQKRVAARQGHYFGASMVESQFKILEPPSAEETDVISIDVSQSMAEVQRETLDKVLHTIDEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4J0</accession>
    <name>A0ABR1X4J0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nadh-ubiquinone oxidoreductase kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673178.1">
        <property type="nucleotide sequence ID" value="XM_066809560.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042620"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20266">
        <property type="entry name" value="Complex1_LYR_NDUFA6_LYRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045299">
        <property type="entry name" value="Complex1_LYR_NDUFA6_LYRM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016488">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006643">
        <property type="entry name" value="NDUA6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8090284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="124" mass="14775" checksum="3122C21AED043DC7" modified="2025-10-08" version="1">MAVTPTQFAKTTAQSANWDVAKRRVLAAYREWIRAAPEIQTMYSVPFPVSVIRTRMREEFERHRFVNKIPVVDVLLMQNNAEYQETMNFWKQTTHVMSYFPEENFRGHERLPKTFMQGFLEGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4M4</accession>
    <name>A0ABR1X4M4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673257.1">
        <property type="nucleotide sequence ID" value="XM_066809639.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042699"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="109"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="687" mass="78243" checksum="9BC01102AC33BD06" modified="2025-10-08" version="1">MITTPSEGSKTGAKKTFGIFSMIDRVDLIEEFIESQPRHCDDELPFKSQDLPLNDQSCKHEFLRGVQDFVLNEILNIQWHFLAPVFRRNGPGSSVQNLSEGVILPISEIKEQRPLDIGHSGTVAKVMVHADHYVHEQESGHFTNAGRPALDSNGMMPCAIKQLHLVGGERYQGHYKDACEKEFDNLLRVRELRHDNLIELLFGYMYKERCYLVFPWADGNLGSFWRDHFPTADMLGPQDHLAKWIFSQAQGLVEGLELVHGNGAGSAPSGQGAATHGTHGDLKPQNILWFMGQSKLDELPNLGHLKISDFGGTQFHRKVSKSRVNWNELHTTDTYQAPETVTGYMVGQRYDLWSLGCVLLEFATWFIQGWQGVDNFSKARSVDSDPSDASTHNNGILLERYEKRRQRSNWADYNRHSTWPADTFFYLLPQGAQRHVFGARLKRSVQNASSHSVLCYHMICHKTLANHKWQHLNDLYKHAKCSRFCADFLKVIEECFLRMNKKNRVSTNEILQRFEKIKRAGESDTEYWTEPPKTPVRARTNLSDLVAEEPDLEGILEASYHSSQRRNSPEDGHYVEQDENNHRDQSPDRSQMAVSNTEAPQKTGYLVPIKMEEGNKRNSYTSSQTAVSLGSVPGDFPRSTDGYKTGIVDEMGTAEARVGSRKRDRMKGCIKRLDNCIRAFVQETFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4N9</accession>
    <name>A0ABR1X4N9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-linked oxidoreductase afoF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005319</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673252.1">
        <property type="nucleotide sequence ID" value="XM_066809634.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042694"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF17">
        <property type="entry name" value="OXIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="46"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8090358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="489" mass="52982" checksum="AC3AA945E99367AC" modified="2025-10-08" version="1">MGQGHSSPSPLAQCLNDVCNGRAGCVAYPDTPLYQIAWVNRYNLDIPVNPAAVTRPNTAEDVAGFVKCAASNNVQVQAKSGGHSYANFGVGGKDGELVIDLKNMQHFSMDTNTWYATIGAGTKLGDVTDRLHENGKRAMAHGTCPGVGIGGHATIGGLGPSSRMWGSCLDHVMEVEVVTADGKIQRASEKENSDLFFALKGAGASYGVITEFVMKTHPEPGSVVQYSFSLTFGKHADMVDVFKQWQDLVGDPKLDRRFGTEIVMHELGLVITATFYGTEDEFKATGIPDKIPKGKTSVVIDDWLAVLTQQAQDAALYLSDIRSAFTARSLAFKSDELLSKDGISKMMKYLDDQDRGTLIWFLIFDATGGAISDVPMNATAYSHRDKVMFCQGYGIGIPTLTKTTKDFMNGLIDTIQGTVPQTLTTYPGYVDPQLANAQQSYWGPNLGALGQIKSKWDPRDMFHNPQSVAPQTLNARQESSAGSKRLRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7L8</accession>
    <name>A0ABR1X7L8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673479.1">
        <property type="nucleotide sequence ID" value="XM_066806183.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039243"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="363" mass="39436" checksum="C77948313C8D8711" modified="2025-10-08" version="1">MPPAKFQQTDSIDSIKKRYEDKEERRVQRALERQRREQLPELCNSVGIDGSCAGFGVLLEEVGQQSQGCEPMTYSLETPVSELEIGDSIDSMVTRREAEVEDDQSAGNCTDSDREIPVPRPENTADDSADSNVASILSKPDSTASAVLTAVVEEPVAAILSADTNQAGNLDRSCPASGPKDTLAHASQTTAGRGKRSREGVEGANGTDGPRPAKRTRQEDTTTRTLRSLPSRARSVPRNGRSPGPRQTQSTRASKLRRVAPSSPKPFTSHSNRLSHKGNHLGRNSIPLLNPLNPLPVPKLGLRSRPSQRSLRTLPSTDGMSKILKALPQAQTTILHYGSLATRQACRQRYVTLMALIQNISFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7V8</accession>
    <name>A0ABR1X7V8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673465.1">
        <property type="nucleotide sequence ID" value="XM_066806169.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039229"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047403728" evidence="3">
        <location>
            <begin position="18"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="445" mass="48620" checksum="6C90144D91281F47" modified="2025-10-08" version="1">MALLLPILAVSIMTTLAFGVGRGDAEMPSTLAVISIDMGDFAEFNWTKIAFVDKPQTRQLVRRIDISSVTNKVGDGINKASGQVGTVVNGAEDKVKNATSQIANKAKDLVDEVGDNIGDIKDIVEKLVMKVLAKIENQLNEWGLRVVRKLNELGISQRYSLHTTTWCKVPRSVEYTNSTTKFSTAPQNCTSLFGEGQNTTFDPVANGGKIFSFSPGDLIANVTSIFLMPKDVQQKLREPIDKGCNTVQRELVNASNSLKRGVMLFTFGPTMIVYAVACGCAWLLLLGLVGEIVYGFTLGRKYPDGKRTLAENVFGFATFFKLVPAIALYALLIASVIVSAVSLITGLVDIMTQAVHIRIGGGSGLVAMSWASFVLILMIRVVLNEQLKDADAEQRTRKREKYGVKNNNPDMARYPSSPDVAGYGAHPDHMSEKHFEDERVVRTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X820</accession>
    <name>A0ABR1X820_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673598.1">
        <property type="nucleotide sequence ID" value="XM_066806302.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039362"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="9310" checksum="7B69C88D54B4546A" modified="2025-10-08" version="1">MATTPPTITITTTTAAAMTSFLAEPVFTMGVAVEGRRCPAPTPACWFSLPAVAPAADTAPPRWHSGGRTLHDPHNGVVSMTTVFTGQGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X883</accession>
    <name>A0ABR1X883_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673600.1">
        <property type="nucleotide sequence ID" value="XM_066806304.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039364"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="724"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="964" mass="107815" checksum="2ABA0C63017A3BA5" modified="2025-10-08" version="1">METAQEAGQARISASAAKKRASGTVQNTISEDRTHDSLYETTSLSLAALGRPVSGRPGVPPGGPPTGRPGGVPPGVRANIPPIPNVVPVGRPGGVPPGVRAQPPPSSTLLDFMAGKPPGTSRRKKSRPGSSHIRVTEPSYLSYDSPNGRNGRPFTDQPMVARETNLLEPEDSEAGSVSQKTQTTCQTASGELRSSIADSATLPEEDCPSDETVRLLSKYLGIPDESGANLETLQSYVSYLQSSITSVPETSNQPEALTVYRVFLGKAHKERMYLDKPHWRQGARRKERLLLGDLPITDLSAYLSKQLAISFIIFRDYDVPTTTNSRYEQAAEHTSESIQPVTKYLVDAIKMFLDRFDPQSHVKDSPTTHTVDSSSDSSDSDDSSDDSYRTMEDNNELESCKLTAPYVAIYHSRGEDMDTFMQLLNDQQRVQFQLMLDFVLSEYGSEYAAVDDLIARGKITHGLIQYLFKPGDVMVEGKDQDAQGHLCRSWPQIRKRIPTSNRPWALMLLRGETSQDLPTSISLEIKATHWEFDGSFTSTHQTLEMKKIDFDYDSEREINSLAFRPLDHVDKATTERLRQRGHWFWKCRRPCMISYKGDGDRNLRGAAGGRYMIDMMAYRKLHPKNVGVLRVPSNLKDLNPNMMEQPKPPTNDSIYLVPPNMKGFNLTTKKWLDLQVDNFNEVVWNTGAFETLVLNVKTKRLIQALISDQIEAEKSTDLISGKGNGLIMLLHGGPGTGKTLTAESVAEIAKKPLYPVTCGDIGTEPRAVEEYLESVLYLGKIWGCVVLLDEADVFLEQRSLEDLHRNALVSVFLRVLEYYDGILVLTSNRVGIFDEAFKSRIQLAIHYTSLTVHQRTKIWGNFLVRLKTLNEEGIDFEDLEDHIEELAQHKMNGREIRNVITTARQFARWERKQQNGGAFLLNYKVMDEIIETSGKFDRYIEKLNGGMTQDQLAEDEGLRLASGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8D8</accession>
    <name>A0ABR1X8D8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673718.1">
        <property type="nucleotide sequence ID" value="XM_066806422.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039482"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045123657" evidence="1">
        <location>
            <begin position="22"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="158" mass="16986" checksum="7A28A1376CCA35DA" modified="2025-10-08" version="1">MRLYPSLGACLFLSLTTGVLSGGHLSSPSSPSPPAPALLSRHCQGAAAAPGQEDPCGGAQVQFQATYDEQTYCKPGLFYNTTQGTPPRLADCQALLPQRHGHAGLLDRQPLAGGLGAEPHDHQRHVPALHLQDWREPDPERNVGYVFFFLSFSSNHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8M3</accession>
    <name>A0ABR1X8M3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002182</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673793.1">
        <property type="nucleotide sequence ID" value="XM_066806497.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039557"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22745">
        <property type="entry name" value="OTU_OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048857">
        <property type="entry name" value="OTU1_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF0">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21403">
        <property type="entry name" value="OTU1_UBXL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="8">
        <location>
            <begin position="123"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8091821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="335" mass="36472" checksum="933204EB99668030" modified="2025-10-08" version="1">MSATITVRIQMPTGPGQVVLDDDATVGQLVEAIKEKAGGTEIHTIKYGWPSAALKFKKDEDDSVRDKTVKSLNLHRERLTVVLFEKPEPAPEPASAPPQVDGAGPSSNEHDPPTIRLPTGNDLVLRVMADDNSCMYTAMMPIIRQSAQERDMDVSTAGALRQVIGQQILSQPDTYNAAVLEKSPGAYVNNLLNPQSWGGSIELNVLSELFDIEICVVSVSSGSVIYQGEGQHERRCVILWSGIHYDRVVETFFAGAADTGDTEFDVCTWDCATSDHILKGALEMAAILKENNYAHDSNAAVYSCKQCGWVGQGEKELIKHCKGTGHSEIQTIEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9F3</accession>
    <name>A0ABR1X9F3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674026.1">
        <property type="nucleotide sequence ID" value="XM_066806730.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039790"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39472">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39472:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="251"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="256"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8092054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="321" mass="35303" checksum="EA9D35B417B7712B" modified="2025-10-08" version="1">MNGVNGSNTGMQGGPGGAGGAAAMAVGPTPAGHQAELNIIYAMVEDLSKQLTENRRVTEDIVSGLGRVRSRARERQFTNDEVLQEAAEEILSQESNLDTIISVLTEALDRAKTSRDANYQLLTAYARVLSTLLQHFHAYKQKHIADVSAWHHSYRAQLAEARAENSRLREQIWEMQEHAGRANAMLRQFRKQYDEDENRKERRVEARARRQEVRFWKRLAMPDVADDDLDAWSDDDDLVDPVEKERLREVERKQAEQAAAGLGSSSSQQGEDSEGEEGGIPGHHPGMGGGLGGVAMERELSSMPTPPPRPASTGSTGGHIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAB7</accession>
    <name>A0ABR1XAB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000228</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674316.1">
        <property type="nucleotide sequence ID" value="XM_066804543.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037603"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046105514" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="599" mass="64652" checksum="08B2C084DA88985F" modified="2025-10-08" version="1">MSLSKRSSLLWTLAAASSALVSTATGFAIPRSAHQARQIRDASQLLPAYDYVIVGGGTSGLTVADRLTEDPDVTVLVLEAGIFAPDADVLPVTDGGTRRQPRYFFPSAPQENLGGRSIDVWLGKMLFADNAQDWSWDGMLPYFKKLAKRFNISTDTSYWGEHSPIQASFPSFQYPGLDPLVSAFQELPGVEMIADSGAGRAGVYWYPTFMDPVKVERSFALNAHYSNHRDRPNYHLMAETAVRRVLLDKDTAATGVEFYTKSSNGSSVATVKATKEILMAAGAVHTPKLLQLSGIGPKRVLEAAGLETLVDLPGVGENFQDHSNVGALIALEGLKQIHPNANDLTADPAFGKWADDLWAANRTGPHSIAYGNVAGWLPLTAIAPERFSDLAAELEAQDHTKYLAADVDAAVAKGYAAQMQGLARAMRSPDTVFARYRVDPTTGASEPILNQPFSRGHVRINAQDPFGADPVVDYRSLSNPVERAVVVEMVKWYRRFHFDSSLKALGPNETAPGAEVVTDEQIAAWVPTALTPTDYHPAGTAALMPRELGGVVDQTLRVYGVKNLRVVDASIMPSLPGGNTCQPTYAIAEKAADIIKSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAJ4</accession>
    <name>A0ABR1XAJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Heavy metal tolerance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000304</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674392.1">
        <property type="nucleotide sequence ID" value="XM_066804619.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037679"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18583">
        <property type="entry name" value="ABC_6TM_HMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF651">
        <property type="entry name" value="HEAVY METAL TOLERANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="542"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="571"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="326"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="622"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="261"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="861"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="862"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8093619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="922" mass="102902" checksum="3A243F102F9C4626" modified="2025-10-08" version="1">MAVDDGESSPSQRVPLATILRVLNVSKIAYPAVVFGVFLIAFISYGIIHAPRDDNKLLRGPGGRPLPVRAKPDRDQDSAKGTINLSDSAKLALRLLHTFIILTFVGHAVLILVQVLIYRKDEWWPGQAAVVFIIGSFFAWSIVLISLIDTTPAPTLVHLFTWVSALPFELLIIASSLSLYTRPHHEPAVGGQQGGHYREKATPWETVEVVIHFGRALLVLGCVVLFVSLAWKSKSKAKNLPGSSSEQEPLLGAGAQSGNGANNGHAYGTTPSAGAGQNGSTKPPKDAWAKPTEPPNVNWFSYIRGFFILIPYLWPKESRKLQGLAIICFLIMISQRVLNVFVPMTSGLITDALSGDDVQTPWLYIGLYVLFKWLQGSQGILSAARTVLWIPVEQYSYRAISTAAFEHVHNLSAEFHMSKRTGEVISALNKGSAINSFLELVTFQVGPMMFDLVVAVVYLTVTFDIYLGLVVAITTILYIYVTIRLASWRVKLRRDYVNADREMEAVKNDSLHSWDTVKYFNAEQYEFSRYRNAMIVMQGFEYWVRVTLAYLNSAQGAVFTFALLIACFIEAYRVAAGFQTVGHFVILITYMAQLQGPLNFFGTFYRTIQNNLISAERMLELFREQPLVDDREGAEPLTSCTGEIEFKGVNFSYDERLRGGKSTIMRMLFRYYNPTSGSILIDGHDVQDLTIDSVRRYIGIVPQDCNMFNESLLYNLRYANQNATDEEIFAACRAASIHDRIMDFPDGYGTVVGERGVKLSGGERQRVAIARTILKNPRITLLDEATAALDTDTEEKIQQSFATLAKGRTMLIIAHRLSTIVNADQILVLKNGTVVERGTHEELIGREGRYASMWRKQSRAQKAREEAEQLRDKARQKLKEAEVDSASVTEDEAESSPGRKKSQKDDQPSRGSPMGRKPPRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAW7</accession>
    <name>A0ABR1XAW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_000481</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674569.1">
        <property type="nucleotide sequence ID" value="XM_066804796.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037856"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF9">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="39"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="148"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="261"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8093796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="39383" checksum="985A352AE336DB6A" modified="2025-10-08" version="1">MPVEVKFQDVTSEPIRARTMPPQLNANNSTSSEKQRRWIKRYRTEVSASSASVLSTITAFPLDSVKTRLQTYPYNGFLHCVRSTYQSEGVRGFFRGVTAPLASVTLVRTVSFSIYQRSKYVYSDWMGRNFGFCPLEHVNKNGAYPTLGTIACFGAAGVTAGSGITFIACPFELTKLSAQVSVLMANQKNVDPQRQAIAMSYHNKGTIQTLRNIVKHRGFSGMYTGLNLHLMRDSLGTGIYFATYESSKQLLTTFSGTNAHKNPIAVLVAGGLCGIVSWALIYPIDSVKSIYQRNALMYSKGQTVPIPKIQFFRRDMYRGLGVSMGRSAAVNAVFFSAFEMFKKKINLMKDFDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBI0</accession>
    <name>A0ABR1XBI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674722.1">
        <property type="nucleotide sequence ID" value="XM_066804949.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038009"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="141" mass="15505" checksum="046F60667FEA12A3" modified="2025-10-08" version="1">MTGPYSPHFTPNYQEVEKVGDLSALLLPSWSNYTFPAPAPFLEITTIETATAFLQESDLTGACITGHLELSLNKCFWFVEYDSGILEAAQCDNKAGIQFMLCYLLWLDNTLANRSKTLATSPPPPPQPGKKISDNLSAEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC65</accession>
    <name>A0ABR1XC65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_000874</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674962.1">
        <property type="nucleotide sequence ID" value="XM_066805189.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038249"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF1">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046382233" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="17"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="193"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="193"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="52"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8094189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="280" mass="27841" checksum="67D6B5143AEF194E" modified="2025-10-08" version="1">MKSAIMILGASALVSAQSLPDGFPKCGTICIPNMVNQASNFNCSGGDWRCLCSNKDFIYGIRDCSDQSCPQGDANVVKAWGKTQCASVGIDIEGIGGSVTGSAPSATTTVTATGKSGDSLTSSATATGSQSAVTTSDILSTITSDGSTITSTVGQTTIFGGVPVPISTQDVVTTIESDGSSITSTVGKSTIFSSASGTDSASPSETQSESASVTTNTSEVETTVTSDGSTFTTKTQAESTSTATNGQEAPSQTSSNPAAMKTVAPAGAFLAAAGFGLMML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCB0</accession>
    <name>A0ABR1XCB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RuvB-like helicase</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000944</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675032.1">
        <property type="nucleotide sequence ID" value="XM_066805259.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038319"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TIP49 P-loop" evidence="7">
        <location>
            <begin position="4"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="RuvB-like AAA-lid" evidence="8">
        <location>
            <begin position="116"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="199" mass="21885" checksum="64E7F31510D5D901" modified="2025-10-08" version="1">MMGQLMKPKMTEITDKLRGEINKVVSKYIDQGVAELVPGVLFIDEAHMLDIECFTYLNRALESSISPIVVLASNRGMCTIRGTDGIVAAHGIPPDFLARLLIIPTTPYDADEIKRIVRIRATTESVAISDAAIDKLAEHGVRISLRYCLQLLTPASILARINGRKEIDIKDVAECEDLFLDARRSASILSSETGRGFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCP8</accession>
    <name>A0ABR1XCP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675142.1">
        <property type="nucleotide sequence ID" value="XM_066805369.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038429"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="597"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="705"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="795" mass="82661" checksum="C46192A5F48E2EBA" modified="2025-10-08" version="1">MHRTPTQHNRGRSGSFAPLAQDEPDLQHENGHETEVEADEEVHSGRHRLSGRARFQQQTNFMNPFNTITNTRRPLPHPRLIRGSYGSPPEEFQEIDIAELEATQIEYYGPRAPSSLSKESDAPTESTFVDDKDKFFCCAYETPIVGVDEKSDPPVTNRPAQGFADYRPFVLKSHFSLLLLLMLGALLGLTVYSTHILPTENQLLVPPNSSNSRNDSMSGLKLRGLVPVRVFGRASVAVKLGRAEQDGNATQPEEQPQGPTTPTLVPTHPVGGTSAQTHPSPGEGHTTTDDSPGKLPPPYPTSPEIQTSPTDGDGGGGVSTPPVSPTTSEPPKDKPPKPTTAEATSPTAKPTTTEATSPTEAPPPTAPSPTEAPSLTEVSSTTDKPTTIEMTSPTEATIPTETPGTTEAPLPTGDPTTAKLTSPTTEPSPTGVPSPTETSPPPPPPPPPTGAPGGQKPGIVCTDTVVLTITKTTTLSETTVYARDLSGLGEGFDVHGPEPPGLGDIFGRGLGGRGKRLAVPVTTLLPRQVPDCTSTVTTTITTEVTVIAQKTVTTTRPPTNTGGGTPKETDNAGSPVITPTQFPGHHFPDPNGGNGSPKTTDNPDPTNKTPGPTTVFTTGDGNPKSPGTGDQVSTTKPGAGDGQPKDTDRTTPQFKLQTPPVQTPKPTPNTDPPIQTPSPKPNPPAPTPTPDLGTPAHPPTPNPDAPAKTPAAKPDVPPASSTSPIDRPSPLSPRPSATPPASQALQVGNASPLEKQPTPLATSDPDEVPPLVLGVVSTPPDGRQHSAAVPAAAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCX6</accession>
    <name>A0ABR1XCX6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675231.1">
        <property type="nucleotide sequence ID" value="XM_066805458.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038518"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="86" mass="10013" checksum="E09D6AD9266A651B" modified="2025-10-08" version="1">MPKQGFVARIHTPLACFFARLQFVARRERIIGSGLLSLVNLDWQRPWQQGNRATDKAQHHTDWDWDWKANWGMPLLPFLDAALDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEB0</accession>
    <name>A0ABR1XEB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">tRNA (Uracil-5-)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001703</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675791.1">
        <property type="nucleotide sequence ID" value="XM_066806018.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039078"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025795">
        <property type="entry name" value="tRNA_(uracil-5-)_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="RNA M5U METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061:SF30">
        <property type="entry name" value="TRNA (URACIL(54)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51622">
        <property type="entry name" value="SAM_MT_RNA_M5U_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="7">
        <location>
            <begin position="129"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="41"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="523"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="523"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8095018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="581" mass="63431" checksum="253CAC1BBB2BCD4A" modified="2025-10-08" version="1">MRISHQGISRLFLGGRSLLTPLASRSYSFKVRRVWNMSGSPAAAAPAAPATASAPPRQANQGTAAAGAAPRQQGKRPFKQNGGGQQKHNKKMRKRERDMKSGSHEEILALDIKALLDEDASAAAEEPPLPEQGSHIDVEVVELSSTGDGLAQLKGSKQVYVVPFSVPGDVVKVKAYRHMQEGYTIADFISIVKPSPLRDDSRISCKYFATCSGCQFQMLDYAEQLRLKRRILIPTIQDTIGSPLQYGYRTKLTPHFDGPSGWSRGKNPFTSRPPIGYMPKGSRKTIDIEDCPIGTDAVRVGMKKERERMETEFGKYTRGSTILLRESTKRIPKDAAAAAAPESESSSIPSDAVVVESDRHTDYKTCVTDNKGMSTEYIDDFVFHNPAGSFFQNNNSILPPSPTTSASTSSPSPTPTLPPYLVDAYSGSGLFTITLSSQFKQSVGIDIAEQSIEYARKNATANRLPDSQAKFIAADANELFQSLGSYPPDETVVMLDPPRKGCDANFINQLLRFGPKRVVYVSCNVHTQARDVGHLVRGETGEAGQEVVGGKKGGKKVRYDIESLIGFDFFPQTGHVEGWRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQB8</accession>
    <name>A0ABR1UQB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_015327</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660526.1">
        <property type="nucleotide sequence ID" value="XM_066819641.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052701"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8061106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="56404" checksum="8A3CF898B8B48345" modified="2025-10-08" version="1">MVDLHVSGLGLPNLALLAVVSATAYYAAWLAYNLLLHPLRRFPGPLLHRASHLPRAYYLVTGALGHKVADLHRAYGPVVRVAPDELAFADPQAWRDIYGHRAPGEPEFEKDGRFYRPIDDMPENIVSARSREYHGALRRQLAHGFSERSMRAQEPIIGGYVDLLVHKLREACSSPVSSSPGKAEEGGKVNMREWLNWCTFDVIGDLGFGSPFGCLESGSYHPWVRRITETIRFGGVVSALMGVGLGGLVQAISRCGGMKSRDEHQKLTREKLLQRIELGAEGRPDFIEGLIRKKDELGMDLLQLQMNASLLIVAGSETTATLLSGATFLLLTNPEALEKLTNEVRSTFADDADITLSSVGSLSYMLACLNESLRRYPPVVIGLPRVVPKGGAQVAGHVIPEGTRVAVWHYAISHDPALWTDPMGFHPERFLGDPRFAGDALDAMQPFSLGPRNCIGKNLAYAEMRLILAKIVYHFDMRIAAESRGWLEGQKAFTVWDKPPLQVYLRPVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT95</accession>
    <name>A0ABR1UT95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Epoxide hydrolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014251</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660753.1">
        <property type="nucleotide sequence ID" value="XM_066818565.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051625"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="5">
        <location>
            <begin position="63"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="483" mass="53509" checksum="A94F435B8F2723BE" modified="2025-10-08" version="1">MMSAPVSPLKSPGLSRHASLTAAPAPAPGAAPAEQEDMGLGGIVLNHMDLKLKFKASFSEAVTKFTIDVHEPFLTTTKLKASLTRYIDDLVDDDGLPVESTDGPPRRIVERTAQFWAASYDWRAVEADLNTRLPQYTTLVKTPHTDFQDPIPLHFVHKRSARPDAIPLIFLHGWPGSFLEVEDILEPLTNPPSADQPAFHVVAPSIPGYGFSPAPRRAGMGYRQCAAAFAALMRRLGYDRYVWQGGDAGNFIGHFLALDFPDQVVAGHSNFWVVPPTPEDQERRSRHEVTEDEDFVMARLGRFTDVGWSYGQIQQTKPLKLAAGLTDSPVGLAMWIYDACAGVVKDPETVFAPQRLITWTMMHWIPGPFAAFSLYKNGRKDGVISTKGVHTMPYVSQPMAISQFPLDLWYRTPLEWAKRTGNVVSCVRHDRGGHFAALDAPDLLVGDVRAFFGDRELSGTQVFVPPPVRTRGSSVGMREWHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTP5</accession>
    <name>A0ABR1UTP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinetochore protein fta4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660894.1">
        <property type="nucleotide sequence ID" value="XM_066818706.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051766"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025207">
        <property type="entry name" value="Sim4_Fta4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42040">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT FTA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42040:SF1">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT FTA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13093">
        <property type="entry name" value="FTA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="30180" checksum="5EDB86D483F391C2" modified="2025-10-08" version="1">MAPPTILAHKSAFLSAQTLQLSQNLAPSGAWRNNSHHHDAENQQQVTEKAVDDALYRLNHALQQHARRVYAPQATRHVAEQIDQLFLDINKDNDDDLAAEDEQDEEGNRLQKGDELRQGADFTSDPMIAALPPNWDQIDAHETQSRPTEAAYYVELQTTLSVLSARRAETRARVERLRAMQNLLQPFRGDADVADDENQNKKVQENLVTRNGEVEKELERMRTLLVRVAGRVGQLPARNATDEDGDTDMIGDLDKAERGKVQSLLDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTX4</accession>
    <name>A0ABR1UTX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660980.1">
        <property type="nucleotide sequence ID" value="XM_066818792.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051852"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="275" mass="30952" checksum="16D2751EB44952EA" modified="2025-10-08" version="1">MGLVRYAQEKTELKRPTDAAKLFSFMANWLEMFSSWRNSVCSTIRSRGSAIRPLRGDMMNLDPLVDTAIRLICRVINEWRTTGADQAQVARNWSTLDRTLLPINQAVTNLTNQYALHTNGTWRTDTVRKAANGFPTKTRLEMQDPPWLPSMLHPQPQADTAMFEQSVSSTKTQSTAKQAPQQPPQQPPSTLLPPPQGNNGFNGNNNPFSQQPPVNNIFPQYTGFNPSNNQYPNSGNQGFNTNGPSYARAAMKRTRTRTTDEGQLKRARWSDELEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUA4</accession>
    <name>A0ABR1UUA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014602</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661104.1">
        <property type="nucleotide sequence ID" value="XM_066818916.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051976"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="450" mass="50984" checksum="BC3B66FC3A790E45" modified="2025-10-08" version="1">MLATLVAIASGCLAAYYLIWRQWESQRLQALAAASGCQAPKILPNQWLRPFGLDKLGKVVEAEKKSRYPLLMLEEHERHGDTYAQYGGGLYTIITRDPVVIREVLARQFKYFDVGSARAGCVRPLIGDSIFTQDGKPWDHSRKLLAPLIRRPTLSPLRLRSRRPSRRRRCDPGQSQRPPFDLTFSVITEFLLGPAASTSSAEGKAFAEFFNTAFKWISKRERLKAFYWLIDGWEFRASCRRARGLVEGIIRRTQQFIDDSGSMEDRIALFRLMKDDNDIGEIRDQFMNLLLAGRDTSGSLLCWCMYVLAHERSLLGRLRAEVGEILDGRLPTKEDFGKMKLLGQFVCEVLRLFPPVPINGRLCNADTTLPRGGGPTGDSPILCPKGTLICFSAYAVQTDKSLWDNADKFDVARWSTERSLTDRITDWTYQPFIGGPRKCLGGEHPTLYTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVJ9</accession>
    <name>A0ABR1UVJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Cytochrome-b5 reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_014172</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660674.1">
        <property type="nucleotide sequence ID" value="XM_066818486.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051546"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF178">
        <property type="entry name" value="CYTOCHROME-B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 12" id="KW-0349">Heme</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="13">
        <location>
            <begin position="6"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="226"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8062075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="463" mass="50088" checksum="89C5EFE59B2304DC" modified="2025-10-08" version="1">MSTSTETEFSAKEVALHREGTDAWMTIHGEVYDVTKYLHDHPGGADVLVEAAGMDASEAFDNAGHSEDAFEIMEQYRVGRLKGAKKFGAQPVKVTLQPPQEKKAAASKGLAVSKSIAASRHRRERHRRLSNQEIIPAAMLEHLKSFAPALGSIGGLGGSKRQGGLGFFEGILAASAVFAVAGTMASHEFSKMVDFHANIFANPTHMRMPKSPRPDPLLVRGWLHPTAYQTLPLVQKVLVAPNVYRFVFELPSPNDVAGLPIGQHVSIAGPIGPDGKAGVSRSYTPVSNNSDKGVLELVIRCYPDGALTGGYLSKLEVGDEVQFRGPKGAMRYRRGLCKRIGMLAGGTGITPMYQLIRAICEDERDTTQVSLVYANRSEADMLLREELESFARRYPLNLRIHYLLDAAPESNSTLKKGMYTVGRVNKDIMTERFPAPSSDSKIMICGPPGMVKGATGGAGRAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVU6</accession>
    <name>A0ABR1UVU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014293</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660795.1">
        <property type="nucleotide sequence ID" value="XM_066818607.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051667"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF152">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="349" mass="38232" checksum="341C349F85D6030C" modified="2025-10-08" version="1">MGMQKGTVILTGANGGLGSAIVKQLDSDAKFSAYHCIYTVRDATRTEPLNLHTTHDVVSLDLTKLDNVREVAKTINANFKLQARVAAGHIPPIRALIVSAGYQEFGKQTWTSDGLDNTFATNYLGHWLLILLLLGSMDKEAGRIVYMGSQAHDPKDPRNSRTGAFTDPKYKTFVSAEDAAASFHAIAEGKWSPATEDAGFRGGYRRYGASKLFLAMMQHELQARLDDADADLGRNNRICVVGVDPGVMSTGMQRLAPWVIRVLIFRILYPLIQLVAPNKGPRPTGRAAEEVLEAAVAGSASDGDGDGDGDGERLELPRDGYFHEMKVMETSEESRDANKRALVWRRRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UW03</accession>
    <name>A0ABR1UW03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661686.1">
        <property type="nucleotide sequence ID" value="XM_066819498.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052558"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8063087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="118" mass="12918" checksum="218B06037B4832A7" modified="2025-10-08" version="1">MSPKQPSSTPRTSVRFSQYSMQAPSVAATMQTTDSAQAEIQEIGTGLDRMENKALSQQRVELSEEKTANMSKLALGAKLERALDRRMSSQDAVMRPRRPTKSAGVMNEKTAGQVETKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UX61</accession>
    <name>A0ABR1UX61_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ascus development protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_014728</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661230.1">
        <property type="nucleotide sequence ID" value="XM_066819042.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052102"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF14">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="14"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8062631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="489" mass="53438" checksum="21E75F162C032289" modified="2025-10-08" version="1">MAMFTQAVVRLHLLCIFFAIGSFVWGYNVGILSSILVHPGFVAAMGELTAARKGVITAIYYLGTWLSYIFISHPVSDYLGRRYAALIGTAVLAVGTGFEAGATAPRAYAMMIVGRIICGLGVAMVSTSVPLYQAEIAPAGQRGKYVVLNHVGFVAGLASGFWVGYAVTFWESTPHQIYVSWRFSAAVVLIPALIFGAGLPLPPRDAPHSRFTEAQRSLHWLREGSCTNAQIDDELTEIQESVEAYRMSGLNWLSLFRERHLFDRLWRASLLQFMAQMCGATAMKYYLPTLFLKLGLGTRVSLLAGGIESSLKIVMTVIEMLLIDRLGRRTTLVAGCVAMSSGLLINGVLGQVYPDNQNRAADIVCVVFIFIYAIGFSLGFGPTAWVYGSEIFPTAIRARGLNFSASGGAIGSIVVAQVWPVGIETIGSNIYFFFFAVTVVCIPIIYMFYPETKGRTLEEMDDLFHASLVRRHVEPVDGDTETVLPKNVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1C9</accession>
    <name>A0ABR1V1C9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011737</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8064990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661744.1">
        <property type="nucleotide sequence ID" value="XM_066816052.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049112"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="9"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8064990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="306" mass="34187" checksum="FD74C3F8E49CB6D6" modified="2025-10-08" version="1">MAILEKIPGIQVAVKVDDRVATEYPNTDPQHRRGFRPVSCVYTESVDDARLTVELAVDESYNFARDEGHHLLFRVEVDGARCGKTECEVTKEQVAGSQGGCERVSLDAARERRDGYEYLQKFRFAAMRKANDDNSDREEASAIDTKRDLGIILVNVFRCVPQKPGDVRSEPTLHDLFRIAEAYGSGNDDYGSRLERRAAKRAKEPFRVVGPFASFKFIYRQTALLREAGVLPPTPPAVAVNNQDDVEPSDQVSRRQPRSAARCADHGEPPRTKAKRDRLSEVDDGLVDTGESSRAGKKARRGHKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1J0</accession>
    <name>A0ABR1V1J0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661820.1">
        <property type="nucleotide sequence ID" value="XM_066816128.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049188"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="117" mass="12930" checksum="1F1DFC75470CB4B0" modified="2025-10-08" version="1">MPRSVCSTPQDATISDPILGSSPVMSSVCWLELVSRRCVEVEVFGPKSGSFSGPAVSVNVTTAFHFTAACSRDKDSLLPDFKSRNRHRGPSADRNNVNPTAVRRMPFRSTRQRNFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2H9</accession>
    <name>A0ABR1V2H9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662131.1">
        <property type="nucleotide sequence ID" value="XM_066816439.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049499"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="2">
        <location>
            <begin position="78"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="378" mass="40740" checksum="5AFFF731157B7930" modified="2025-10-08" version="1">MNTTTSVTPKTIVIVGATGHPRLLRRPDLPVPPPALARPRPNAGPNISRRPKPRRAGRRGRAGGPRDRGGDTTDAGGASSFEAAFADAHAIFLNTDFWAPYRTALAAGATQDAASRTGFETEMRHARHAVAAAAKSASSTLERLVYSALAPLREASDGRYTHSYHWDSKAAAASWIASPASGVAEKASYIYVGAYSTNPLILPQKLKKEKTETTMNAGAAGDEEYEYVMRLPAGRRMRMPVLDIAASTGPFVRCLVEDEPANTNLLAYDEYLDVDGLLRAWTEAVSSSDDDNDEKTPLPPRFVQMGLHEMNRATGLPLEVLEAPPFVEEFGYMGGVSGGFVEPHQLRNRPGTRAFAVTLKSHGREYLLGAKLPTAATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2K9</accession>
    <name>A0ABR1V2K9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012171</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662177.1">
        <property type="nucleotide sequence ID" value="XM_066816485.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049545"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774:SF1">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="6">
        <location>
            <begin position="69"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="235" mass="26180" checksum="B6E3F9C8020D54B2" modified="2025-10-08" version="1">MNLAALLSLLKDIAFWSLVAYLILHMAFFQNAPNFISRLFRPLTTSTRLGVSGSEGGMASTTIPEGAEKATVAAGCFWGVEHMYRKHFAGKGLYDARVGYIGGDSSNPSYREVCNGRTGHAEAAQIVYDPKQLTYRDLLEFFYKMHDPTTSNSQGPDVGTQYRSAIFTHGPEQEKIAKEVTAKASEQWWKGGVVTDIVPAGQWWDAETYHQLYLDKNPGGYECPSHFLRKFPPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2W7</accession>
    <name>A0ABR1V2W7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="13">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_012281</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">May mediate the reduction of outer membrane cytochrome b5.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="13"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662287.1">
        <property type="nucleotide sequence ID" value="XM_066816595.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049655"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8 13" id="KW-0520">NAD</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="84"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8065534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="335" mass="36763" checksum="80F0322A64B58472" modified="2025-10-08" version="1">MFARSAFRAAQPLKRNLLSRSYATEPAKGGANPLLYAAGAAAVGGAAYYFTATPSGKSAAHKAEKEVKSVASGTPKVAFTGGDQGFVSLVLEDSEVINHNTKKLRFKLPEDDMVSGLHIASAILTKFKNEGMEKPVLRPYTPTSDEDDKGFMELIIKKYPNGPMSTHLHDMVPGQRLDIKGPLPKYTWESNKHNHIALIAGGTGITPMYQLCRAIFNNPNDKTKVTLVYGSLTEEDILLKKELEKLENTYPQRFRAFYVLDNPPKGWAGGKGHIDKNLLKTVLPEPKEENIKVFVCGPPGMYKAISGAKVSPKDQGELTGILKDMGYTKDQVYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V398</accession>
    <name>A0ABR1V398_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7 9">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_012403</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8 9">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7 9"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662409.1">
        <property type="nucleotide sequence ID" value="XM_066816717.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049777"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09617">
        <property type="entry name" value="Peptidase_C12_UCH37_BAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017390">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041507">
        <property type="entry name" value="UCH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF16">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18031">
        <property type="entry name" value="UCH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038120">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="11">
        <location>
            <begin position="4"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="8">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8065656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="35858" checksum="D2026BA796566732" modified="2025-10-08" version="1">MSGGWNTIESDAGVFTYLLDNLGVKDVQFEELLTLEPDALASLYPVYGVIFLFKYPTNEPYTSTDKPLDGEFDRDASESLFFAAQTIQNACGTQALLSVLMNKEGDVEMGGPLREFREFTMMLPPEFRGEALSNSELIRDVHNSFAKSSPFVDETQRTSGETEDAFHFVAYTPIAGKLYELDGLQPAPISHGPCSTDEFPTKVMDVLQRRIGRYEMSEIRFNLMAMVRDLRIKAREIGDLDMLEREERKRRDWQFENALRRHNFVGFAGAVLQGVVQEKLKEGNGAYGKWISDAKDASRKRVESRRKGGGGEDTEMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V481</accession>
    <name>A0ABR1V481_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ENTH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662753.1">
        <property type="nucleotide sequence ID" value="XM_066817061.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050121"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16992">
        <property type="entry name" value="ENTH_Ent3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276:SF45">
        <property type="entry name" value="CLATHRIN INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276">
        <property type="entry name" value="EPSIN/ENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="2">
        <location>
            <begin position="27"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="364" mass="38619" checksum="FDF1A73EB431CD2C" modified="2025-10-08" version="1">MDLNNLQSTISNLTLYDLKAGVRKVQNAVMNYTEMEAKVREATNNEPWGSSSSLMQEIANGTFNYQTLNEIMPMIYRRFTEKAAEEWRQIYKALQLLEYLIKHGSERVIDDARGHITLLKMLRQFHYIDQNGKDQGINVRNRAKELAELLSDARANKAKYTGVEGGSMGGFSSGSGSGSGGRYGGFGSETGGFGGASAGYGGYSGGVYGDGGGFGGQETNDYREPTRRAEQFEEGTERAGVKKTTPAAAPPKKAKEPEVDLFSFDDPEPAPSTSAAAPLPAAAPSNGSSALASLSNDDDEFDDFQSATPVPAAQSSGSSGAFAIPPPMVTSSAQSTAQFAAPQPLSGPQNANINSMMSAISPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5B6</accession>
    <name>A0ABR1V5B6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662850.1">
        <property type="nucleotide sequence ID" value="XM_066817158.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050218"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="100" mass="10743" checksum="ED3FFA3B03BBDA4B" modified="2025-10-08" version="1">MAENSATAHMDEKKLDEAAQRALQLKEKQHADFVRANGVLDFVASAKHSLLFQPNMNWNDMLSGAPISISVMGAIFIASTTTLASGITLLPPTGGFKNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5C3</accession>
    <name>A0ABR1V5C3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protection of telomeres protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_013130</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the telombin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663136.1">
        <property type="nucleotide sequence ID" value="XM_066817444.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050504"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028389">
        <property type="entry name" value="POT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032042">
        <property type="entry name" value="POT1PC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011564">
        <property type="entry name" value="Telomer_end-bd_POT1/Cdc13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513">
        <property type="entry name" value="PROTECTION OF TELOMERES 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513:SF0">
        <property type="entry name" value="PROTECTION OF TELOMERES PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02765">
        <property type="entry name" value="POT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16686">
        <property type="entry name" value="POT1PC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Telomeric single stranded DNA binding POT1/Cdc13" evidence="10">
        <location>
            <begin position="35"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Protection of telomeres protein 1 ssDNA-binding" evidence="11">
        <location>
            <begin position="170"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="340"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="552"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="968"/>
            <end position="994"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8066383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="994" mass="110246" checksum="954FC1849501E5DE" modified="2025-10-08" version="1">MAGRESTSPASRSVLANRPLPPTFISIQDALNGDLAAKGSLVNIIGVVRDVRPPIPTRNADWKCTMTMVDKSTEDENTGINFSVFRPERSCRIRVTWMSCSSSSAIPMPPKPANDALKSHTGPKAKQPGDEEQEYVSWLYHAVNKDTLPGANEFEEQANRSLNIREKFSLLKDVGDGGFSDLIVQVIKDPHDLVDKVSMWVTDYTENKYFFNHSWDTSNADAGRDGDPYGYTLAFQNPTTRGWPGPFGKRCLQLSCWEPHAGHLRSQVKAGDWIRMRNLQIKYGRNGGNLEGFLREDKAHPSRLGFEVLEPSEGADPRLKEAIRRKVEYGKKFKQQKEALAGSKDLKPVGAKRKGKGEAVTLNSKQRRKLQRAQNEQKVEKQQAQKAELLGLNKQVTCESEDQPVSPLDRILDGVSWKRSGINGEEHVALPFTNVKFRANVRVVDFRPRRLEDFAAGRKVTDFAGPKSWEWRFALELEDASPRAKGEKPERIWALVDNYEAQQLTNMDAVNLHQDPDQLSQLREQLFKLWGNLEECKRPEYDAHLESIRRANALDPPPDSSDNEGVQDGPNQLNGHRLTTKVSNKPFTCCLQQYGLEIPESDPMKCDAGEGKRYQRAFKLFGTRLIIPARLEFVHIPHAIPAHPLDVLAAPDRRREASRSHSPSSCIRLRARGDAGAAQLPPELERFAQGLALAPAVHPARLLRGRREADAVHAAQRLPLGGAVARRPAEQERPQVLPRAARDVVGPARRRQEVPAPRVLRPRPAAHRGPAHGELGAARAGQNLGHLHLLLLLGRLLPFWLEEDVAEAEVCEERVPHVWLFFLHALLGRPGRVDPVGTRVEPARSQVGITVPARIFHLQRIVAAADLRLGVPGIVLGVHEDGDVGKVVVEVVQVGQIHEGLAALVEHGRAVGRIGRVRHIADDPQVGGAGDAETARICRPRDVVLGARREHYVHRDVAVAQRLGNAALPRRRRGGKGDGGNTITRGSSRTNAGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5S1</accession>
    <name>A0ABR1V5S1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663293.1">
        <property type="nucleotide sequence ID" value="XM_066817601.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050661"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="14778" checksum="66554179F92B75E4" modified="2025-10-08" version="1">MIGSLPTELLLQILAIDSAADLCALIRASPVAHRVFVSAKRVVLPNILSRALGPVLRDAVIATLSTPAESTSSKLHPEIRGALELPIESAFALVRVNRDVQFFTDEFELLRLPELRKLDPEAAVSQAAYFATSSGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6G2</accession>
    <name>A0ABR1V6G2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Threonine/serine exporter-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013520</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663526.1">
        <property type="nucleotide sequence ID" value="XM_066817834.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050894"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="474"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="525"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="606"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="631"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="654"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="684"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="739"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="4">
        <location>
            <begin position="344"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="302"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="778" mass="84469" checksum="D707189D12676221" modified="2025-10-08" version="1">MADNSPPAATSPATNNGVKKEKGRVRFNSMVGGEPPREIPSPIDDNDEKQQRNLSPVRRPRPSLLRGSSYNSVLDADALTPQEPLSPAAVSAIAAHQRAQEVAANMLGSSHSAPSSRRASLDSEATVNSSGELIPRINLPLEEMDRDGQGAALERMNSVERRNHNAAAYDLVKFHTLSPDTLLETSEKLPLARVPGNNSPAGYASDFETSLHHGHPREGVLSHLLKLYRVPDGPMQGKTFSGYTTPGSSGTATPTRRKWYDQNKNASQDTLATLAKASAILANPNEKPRDNSNSPSPYGGKPPKRPKHNRTHSGKIKTLLGKNRMADEAKITIHVADILKRQEYIIKLCRALMLYGAPTHRLEEYLRMTARVLEIDCQFLYLPGCMLISFDDKATHTAEVRFVRLNQGLDLGKLKDIHEIYKEVLHDIVSLDDAIGRLDEINKGKTKFPVWVRIIAYGFASAFVGPFAFQARFIDMPVAFVLGCIVGFLQLAVAPRSDLYANVFEITASVITSFLARAFGSIQGGNTFCFSALAQSSIALILPGYLFLTAALELQSRAIVSGSIRMVHAMLYSLVLGFGITVGVTIYGAMDDNAVSSTTCSNQLNWRWNFFFVPLFALCLSVANQAKYKQMPVMVVVSVAGYTVNYFSGLRFKAAPKSATCWVLSLVIGILANSYSRLRHGVAAAFLLPSIFVQVPSGLAATGSILSGLSTANQITNSTQVVNGTTTVPVAQPNDLQNIVFNVAASMIQIAVGITVGLFLAALCIWPMGKRRSGLFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V713</accession>
    <name>A0ABR1V713_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013732</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663738.1">
        <property type="nucleotide sequence ID" value="XM_066818046.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051106"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF16">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="342"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="348"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="388"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="417" mass="43310" checksum="F88BAE1BAAD1468D" modified="2025-10-08" version="1">MSTQTVVATEPQSIPMAELELRRPERCHGRDLGDPEAGNSPGMFTASAADTSPAVVQHLTVVDQTPAVPYFKLLVAGFSYICAGINDGTLGPLIPHIINTFRIGTGEVAIIYVSTFAGWLLAAATGPLLTPHLTLGQLLAAGAALQLLAQCLRPWDWDWSRGGSPFPQFCATFFVQALGMAYQDSHANTFVSGLPHVPHRWLGFIHACYALGCLVGPLIATGLVATTSGSSTTTGTGTGTTGVDGGWRRVYFILIGIGVLNMAGVALAFKDSLWSKAAHPSNATTTTTTNSRRTKAAFQELVALLRSKALWLLSLFYFFNFGALLTAGGWVVEFLTAVRGAPSPPRATSPRASGPACSSAGSCSPSPPSASASAACSSPTAPPPPPCSSSSGCSPTSSRARSRSVSWASSPGPSSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V789</accession>
    <name>A0ABR1V789_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Heat shock factor binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663819.1">
        <property type="nucleotide sequence ID" value="XM_066818127.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051187"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009643">
        <property type="entry name" value="HS1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424:SF0">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06825">
        <property type="entry name" value="HSBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7410" checksum="754590626183CF4E" modified="2025-10-08" version="1" fragment="single">SHILTNATVQPSDELTVVVEELLNSLSNKFAGVSSEIFAKMDEMSRRLDNLESALKANQASDSASSSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7I0</accession>
    <name>A0ABR1V7I0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichol kinase</fullName>
            <ecNumber evidence="3">2.7.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_013896</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.108" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663902.1">
        <property type="nucleotide sequence ID" value="XM_066818210.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051270"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032974">
        <property type="entry name" value="Polypren_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205:SF15">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="558"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="657"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="710"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="755"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="795"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="835"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="469"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8067149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="909" mass="99725" checksum="ADFC1AC3F69AC1E7" modified="2025-10-08" version="1">MPEQLDPSTAAQKPRDDSNEEQENLRLLSRSPHPYARQKSELLEPSGSFAYPPRGSPEGSHPQRATAFPSIARDTSPSSDSGTEADDEHFLKGLPAPRARLHKGLRGRNEVASGTSTPLPSPGPFDDDDGRRHMSTSHTLKKEVPIGKTVRSASENSRRNKEIARRLTEVLLLGALGVAVYTNKQSRPALYQWRLELIASLGIMGTLVLLYPLRLMIWGYKHRSTSALPPAWTTISIPTTFDPAPLLYPPAITMLVSSLISMDNQAILLPNIILSLCSLPPSLFFASSQDHACNTWQWLVTCIPLFLSSDATPLKGAGSVGEPPNAKLANLLPEVAVLLYPLHQHLCKTLHSMTTTSLLTAELQLLSVALINVLLLSSSPQAVILKGMLWIGGLDLLILGTNVITWGISLARVPKWRFKRVVSTSKRSWSLLTTWMPWKRVRHDLFHATMDSSSCSSCEAFDEAEDSESLQTGATKSRKRRQSAGLNDPRTTGLDVPAKDSTSPPKYASVHWVPNRAVEHLPRKSYTHTPSGRKKRSASTSVRAFFSMTYEQATWRKWLYALYVYILIIGSVFVPHRWVGVKDFVQTNALHSYEPVGWALGYLFGDLPKFRLEVVSRNLEWWICLPSRPDIDDLGSLDGGWVQYLRHTIIGDANTRLLISAYCLAVISIGLIVVFRLSPVYEVDTRRKVFHFMMVAMFAPSIYVDPTFAGLALSIVLAVFLLLDLLRASQLPPLSKPLAAFLAPYVDGRDLRGPVVISHIFLLIGCAIPLWLSLGSLPRGGTGYLEGWEVPTREVSMVAGVICVGLGDAAASLIGRRYGHRKWLWGGGKSLEGSVAFAVAVFLGLLAAHAWIRIGGWPSSTELDSLGTTAFKAGFCASMASLTEAVLTGGNDNVVVPVVLWTCAKSLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V812</accession>
    <name>A0ABR1V812_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664088.1">
        <property type="nucleotide sequence ID" value="XM_066818396.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051456"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045594409" evidence="1">
        <location>
            <begin position="29"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="243" mass="26498" checksum="6DB008FB74E9018C" modified="2025-10-08" version="1">MQLLSAQSFGRILAALLLAPSAINLCLAAPQPIGTAEGSATLVARKDTSALKSFKEKVDAAPAKIRQDQTKFVDFSKKDEKSVSSVGYNQCFGVIIGTSKAAVVGHYTCGSVGQQKAERELKAAWDANKNDKLKSPKVYIYAKVKVGKDHKIQEGTFENPADLDAFKKIVKDLTGKDASIEKYHNVDDVITESKNGVPTELPGFDQKTADKYSKYAGYYVTKGLLGLDVKFMTLDMQKDSYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGW4</accession>
    <name>A0ABR1VGW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010684</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664289.1">
        <property type="nucleotide sequence ID" value="XM_066814999.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048059"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF13">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045873079" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="22"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="65"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="589"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8070481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="659" mass="70367" checksum="B607B0F69F877E32" modified="2025-10-08" version="1">MAPLNLFLGVLWPLLMVQAAAAPPSESTVQACREIADALPAGRVAYPLQPAYTLETQRYWSLALRELRPACVVSPRDAEQVSAAVRVLNKHPDVQFTVKSGGHDPNPGHSSIDGGVLVAMREMVGATYDAATGLARVRPAGEWNDVIGDLEPSGVTVVGGRLGIVGSIVGWETVMPNGTIVNIDAKAQPELAVAMKGSGSQFGIITQFTIEAHPIGQVWGGARIYDESKKDALYAALHNFVPGNADDPKAAVIFTDLAITLNGSAAIVFYFHEGAEKPTSGPLMPFLDIPPLVDLAKTQSYAQLLKANGDLGSLSVARFSFRTFTIPYIPTNPGLYAEISAKWRAITSAYLTLLHPTAQCSTDFQPLPAVIGRRSEARGGNAMGLAGADPDRLVLELQCGWINGLDDATLYALARDMTDWLQGRLPEWLAQAGLAADEAYMPLFMNDAAGDQNVTGSYRGHARYKALQESVDPMGMFSTRAGGTSTRIANHVPEVGEPSQPRMVLTAARASKALLRRVEFVCRARSPVDDLPEARASVLGNFISGGRRPGAIPRSVNVRSEALEWKLSHPADGAIAIIATRGHKCRTAGVRERPDEPKELLTGRSSRHPAGCFSSSPPQIGDAVKVGFWGNPWRWGLLLGLPTCHGYHLTTVGGIGGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH65</accession>
    <name>A0ABR1VH65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664382.1">
        <property type="nucleotide sequence ID" value="XM_066815092.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048152"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="50116" checksum="E7D33009F6BB4A5B" modified="2025-10-08" version="1">MAIFSWKVFRHYVSASMQSAPVTYQTFRLVFINGDANIATPFRLSRDFIKRRRLISTTAMVFMVLSTVYVLVFPTLVGSMTGYIGVMMTFVKDHNGTSIPFARFDYAAYVIHDGHRINLTDDYVVPYSDAANARSMQDPLATIPSPDCSDSSRACAIKNATSLYVSRNGFYGLSDATSEWDMAPVMVILEPPALNISAFYLAGSHLSQEPGPDPEDMLYGNGWVDPRTGECPFNDSGRLMWTAHGQLYSMDDIKANGACQPLMNVYEWGFSFVQALLNCVLLAVWSVGLWLLWLAAQFKLPLQREKEVTKGWRAVSYLADTMCRQFDKAGIDPDRLREKPLKQEINKHLNGGDISFISDCPEKSRLSLGRGLLMWFKDNKWWCLVLTVLLLGTGLSQRPVLYPLFATVYGILMAMALVDGVASRLLVILPFMIVSVIGLFYALLWVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHU2</accession>
    <name>A0ABR1VHU2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664255.1">
        <property type="nucleotide sequence ID" value="XM_066814965.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048025"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045519762" evidence="2">
        <location>
            <begin position="20"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="24648" checksum="A447CB704D390585" modified="2025-10-08" version="1">MQYSMVMTSALAVFTTVNAAPLERRTPQGVLGGLLGDGGSGGSGAGNGSSSHPGGVGSLLGGLTGRDAEVEKRSPQGVLGGLLGDGGSGSGSGNGQQQGGHPGGVGSLLGGLTGRDAGAEKRNPQGVLGGLLGDGGSKPSGGNGQEQSHPGGVGSLLGGLTGRDAEVEKRSPQGVLGGLLGDGGSANKGSGQAQEGHPGGVGSLLGGLTGRDAEVEKRTPQGVLGGLLGDGGSANKGNGQEGGHPGGLGSLLGGLTGRDTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIE7</accession>
    <name>A0ABR1VIE7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664788.1">
        <property type="nucleotide sequence ID" value="XM_066815498.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048558"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="679" mass="75494" checksum="7008967079809949" modified="2025-10-08" version="1">MKQSRDIRGFFAKNPSGGATPTTKSETIAPPRPKAVPMQPTSSSPNIPSSPNVPSSPITPQRRTKVPLSRDDVIRGSDDEDSGDSDDSLESLSEIAARQRKPGQAPLPSTAPKAKRVASANSRAAPVVQTQPQKHKYDLKALLKHAREDDAADESARRAEALLKQDDATRKVNEGPKGEDEPRPTNMREAAKELLHGDEEGSKGDKLVRAMNRTTGDASQPHYYFFEFEAPSRDVRRTPFPRLAAKKQWSFLADTSTREETFVRGLPTALASKGKELPPELYQWVLDEVCLEKNMQLRMQYCNLIALCRENTRRLVDVKRLQHILESIGSRKFPDENSQWHSSPGLEQPYGERNWSPISTFLKVLERMAPNLAPESMMGAIQILVRMSLDPIVSRDIRIRIDHFSTIEALVSALPGTGEQWNSYCSQMCLYLHGGVEKTSQRQIAISLLPPSTPRLCELRRRLAAAALFRQPGLSSLHPDDALTRKDILARLNAPEFTVTHETDYEELQANVKLLNMVIDDGLFLRSPNVTQCSTPATPATPSRMPNQILPSAATLAGGRLTVSQPRSSSNSSSPIDTSAGDFDKFIDILTRKLKIIHDTISDNSLVSRKEVKAAIDTVGKRLAHTVRTRPPPKTSIIDDLIGHTKRDEDAGKPKQREFMKKWALQKKKDVDVNDDSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIU8</accession>
    <name>A0ABR1VIU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664946.1">
        <property type="nucleotide sequence ID" value="XM_066815656.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048716"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="172" mass="20166" checksum="6D445024F55CD550" modified="2025-10-08" version="1">MIFTSSTTRHSGVRDYFRSWVQANLEDRLRPDAADLQDDVGWWRATSTPRYEYCLFVDDLCLESVDHPDVDSPIVKLLHKGWESPYSPQERNYKVPTPFHDGATEHEEEDVGWMYMPVQHYLGKYDLLGKGDWDEQYVRPPYIDGTEDESTFPGHWRQESPICDCLQAVYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUA4</accession>
    <name>A0ABR1VUA4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665774.1">
        <property type="nucleotide sequence ID" value="XM_066813812.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046872"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="58" mass="6016" checksum="3500C52D6C16D1D0" modified="2025-10-08" version="1">MPAPMEPTQQAPMDASPSDGVISQQPSAEPQPEMNLRGGEEAGCEICCGLCACEESCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUJ2</accession>
    <name>A0ABR1VUJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665863.1">
        <property type="nucleotide sequence ID" value="XM_066813901.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046961"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023442">
        <property type="entry name" value="Ribosomal_eL24_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01073">
        <property type="entry name" value="RIBOSOMAL_L24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL24-related N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="94"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8074923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="160" mass="17945" checksum="26CF3C621C18D4FC" modified="2025-10-08" version="1">MRTYDDTFSGQRIYPGKGKLYVRGDSKIFRFQNGKSESLFLQRKNPRRIAWTVLFRRQHRKGISEEVAKKRTRRTVKAQRAIVGASLDVIKERRSMRPEARSAARSAAVKEAKEKKAAAAASKKEDKAKRATTASKGQTGRIVGKQGAKGSQPKPKATTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUR6</accession>
    <name>A0ABR1VUR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beta-xylosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009663</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665940.1">
        <property type="nucleotide sequence ID" value="XM_066813978.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047038"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09001">
        <property type="entry name" value="GH43_FsAxh1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF15">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046381622" evidence="6">
        <location>
            <begin position="21"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="7">
        <location>
            <begin position="20"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="565" mass="60976" checksum="220DED0BC966DFDE" modified="2025-10-08" version="1">MVSQRTVIVLAASFAQAVFAAAPLYGQCGGSGWAGDTTCVSGSCCQVSNEWYSQCLPCSGGGNPAPSPSTTAGGVTTSTVRTPAATGSFNNPVLWDDLADLDISRVGDAFYYSASTMAYSPGAPILRSYDLVNWEYIGHSVPKLDWGSKYDLAGNTRAYVKGIWASTMRYRPSNKKWYWIGCIEFGKTYVYTASDVTGPWSLAGTMNTCLYDVGLFIDDDDSMYVAYGNTQLRVAKLASDGLSITSDQQIYDGNSGGQSTLEGSRMYKRNGQYYVLVTHPANQEWTLKSSKPQSGYSIKVLANAVRPPVSGGGNPHQGGLIDTPNGDWYYMAFEDAYPGGRIPVLAPRDLGLGWLPISGHVKWRLGNELPDAAAREARRLVHRDRFLQRHRPRRALGVEPQPGHEPARNTLTRRIRGPVSTATIVLDTSNMADGDRAGLSLFRDQTGWIGVRNDGGTFTVAMVNGINLDSNWNTASTGTTSASAAASKGKIYLRGTVDIRPGGTRVGQFSYSTDGTSFKQLGNGLTLNNNWTYFIGYRWAIFNYATKALGGSVSVASFTQTVANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV19</accession>
    <name>A0ABR1VV19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_009761</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666038.1">
        <property type="nucleotide sequence ID" value="XM_066814076.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047136"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16456">
        <property type="entry name" value="RING-H2_APC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024991">
        <property type="entry name" value="RING-H2_APC11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12861">
        <property type="entry name" value="zf-ANAPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="35"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8075098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="113" mass="12958" checksum="8AA12B0DB00E897D" modified="2025-10-08" version="1">MKVKIKQWNAVASWRWNLPEEDVCGICQVHFDGTCPTCKYPGDDCSLLSGKCGHNFHMHCIQEWIKQESSKGQCPMCRQKFEWGPDLDLQQEQQDDQQPQEGQQPGGMVMADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV89</accession>
    <name>A0ABR1VV89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="6">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009829</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666106.1">
        <property type="nucleotide sequence ID" value="XM_066814144.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047204"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF89">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="575" mass="65436" checksum="2B0AAC65E924401E" modified="2025-10-08" version="1">MHQDVVRLTEQNHVAMAALFRRPTRLLTVVAAIVVLYILVIFIPKPREDLYGFQYFRSSFDWSTLTEHNPVAKLTPLPRGSPKSLPKFQHDFASDKAPSRERLQVLESRRAEIRNAFLKSWDSYKKHAWMYDELTPVSGEGKDTFGGWAATLVDSLDTLWIMDLKDEFRHAAAAAVTLDWSKTKETACNFFETTIRHLGGLLSAYDLSKEAALLEKAIELGDMLYSGYDTDNRMPPFFLDFDLAKEGLLVPGVHDPSAALTGQDKYYDAIDRVARVLDQTQNSTRLPGMWPTFLNMRNLDFSGQRGFTLGALADSLYEYLPKMYAMTGGLEPMYEKMYRNAMDAVTKHLLFRPMTPNQDDILFTGSVYVSSQEGPELEAEGQHLGCFVGGMFGLGGKLFNIPEHVKIAEKIARGCAWAYNAFPIGIMPETFTLYPCPSLEPCAWDEEYWEGTADRRLPQGFKNTMDPKYILRPEAIESIFFMYRMTGNPEYQEMAWRMFQSIKKATETKLAFSAISDVTVAKAADTEKQDSMESFWTTFFLIFSPPDLIDLDKYVLNTEAHPFLRPVAHGFFTYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVD3</accession>
    <name>A0ABR1VVD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665722.1">
        <property type="nucleotide sequence ID" value="XM_066813760.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046820"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="4">
        <location>
            <begin position="169"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="371"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="394"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="414" mass="44865" checksum="EA543CA77A8100AF" modified="2025-10-08" version="1">MSFTEIPILDLALARDPATKPGFLADLRHALMEVGFLYLKNVGISDELFARVIKEGRSFFDIPTEEKLKIEMKNAPSFLGYSQLSAEITAGQIDHREQIDLSTEHPVPGPDAPRHHNLLAPNQWPSESVLPDFRPVFIEYMSRMGAVSVQFTSLIAEAVGLPPDAFDKYFDGPRQQHKLKIVKYPDVAELGLPSGPGSGAQQGQGVGPHKDSMLSSYLLQASAHRGLQVQNMRGQWIDCPPLEGTLVVAIGQGLEALTQGVCCSTTHRVLSPAAGAGARYSIPFFQGVRGDATFADLETVGVGTVPQDVRDQRREVLEANGGGRLDDVEFTFRGGGVAKTLGEATLRNRVKSHPDVGERWYPDILQDIREQQAREAREKNEGTGVVGKGADEATASQGQSHATNNPTTAAVEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVM5</accession>
    <name>A0ABR1VVM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666236.1">
        <property type="nucleotide sequence ID" value="XM_066814274.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047334"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029498">
        <property type="entry name" value="HeLo_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542:SF1">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14479">
        <property type="entry name" value="HeLo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="213"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="578" mass="66297" checksum="E4A129FB318D1E58" modified="2025-10-08" version="1">MEKDKLIGWAILAGISEEETQLKPSMRFNRHTMIDALKEIQTLLLDVGRLRRQYKLELDVVEGPTQGEAEQPVNQPEGNAADATDSPVFGRSSRLEKRALEFFEKTRQVPRKLKWSALDNDKFEELLANLGKLNDGMMVFLESYDREQLLKRQEITLMQVLQLSTKMDDLLGLLNSQKAANVEHRHHLQHNFSDNSRQKYSERFERLTRFRALSLDIELGGASQTSSISSRSEDNSRLSRDDLELEISAQSQTPEQFSCGRYQGQSVWMEWRYYEPHVEERDNEEDESIEDSREPPAFVHSRIARMADLLRSKDKPPEFCVPDCVGYVLDTEECRLGLVYEPITPVLGIMQPPVSLLDLLSEKKKPSLTTRIRMGRLLASSIWYLHATQWLHKGLRSQNVVFETPVYFKSGLRSGPPRLVLCGFDYSRPAAIDETTERPVGNLWHEMYRHPNAQFDFPREGRRGFRKLYDIYSLGVVLYEIGIWRPVHALLGVDTQPSKPEYRLKTSTVKTVRSRLLAQDSLEELEAQTGSLYAGCVKSCLSGDFTAEDNGSGDYGNESRFVADFWENVLQKLESTCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWU8</accession>
    <name>A0ABR1VWU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666670.1">
        <property type="nucleotide sequence ID" value="XM_066814708.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047768"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="40394" checksum="B52E00449CB94018" modified="2025-10-08" version="1">MAEEDDKKQQIERTRTRLRGYLEPDNKFKLERHIGSGAEAHAWLVQRQGPNDGDLGTKYVIKTPSFIERPDRAERFQSSEGTTVFDKERKLLNRLTERHAVIRACVAMAYVPAGPPMDRYSRNEEPCELTPDSYGYTHNDMYTANIMIGAMLGDPDDLEHLICPVFKFIDVGNHTRYPGGEGAGVQRNLFSVGACMAEVVMLQSELTIDIGEGRANEDAMDYEIKDGGPVFGTYAHQLLPSDDTDYELPRPELDPDLRRLICRCAALDPDDRPSLTNELLPTVKRAIRERDVAYYARTSYCDETQETDEAILKFLQEVLGAAPPPPPPPAGSGSGAEGGEGPESFRTRPRPPRDPRELSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYC5</accession>
    <name>A0ABR1VYC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010014</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666291.1">
        <property type="nucleotide sequence ID" value="XM_066814329.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047389"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03046">
        <property type="entry name" value="GST_N_GTT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF9">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01150">
        <property type="entry name" value="Main.1:_Beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="86"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="251" mass="27357" checksum="2DED3F170E138BD3" modified="2025-10-08" version="1">MVLTVHHLQVSQSERIPWLCEELGIPYELKIYQRAPALAPPEFKALHWTGSAPVITDGDLTLAESGACVQYICEKHGGGRLFPTASHPLYADFLYWFHWANGTFTPTIGRAGMVPDGQDGGGNPMVAYSKKKRDDGFKGLDARLRDNDWLAGNEFTAADVMLVFSLTTLRYFVPMELAPYPNILAYLKRVGEREGVPARDEEVGSGDGVGPGRGGARVVLQEVGEGGQECPVAGPCSQTRRLMLGGILHML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYK7</accession>
    <name>A0ABR1VYK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal lysine N-methyltransferase s.t1.c11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009606</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665883.1">
        <property type="nucleotide sequence ID" value="XM_066813921.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046981"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF137">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="19"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="453" mass="49066" checksum="38005D84AF875C08" modified="2025-10-08" version="1">MEPHEQLLQWAEAKGVKLDGIAPQRLPGRGMGIVATRSIQPDEILLEVPARCLRSIETVPKALSRRLPRDISVHGLLAADLALDASDTYAAWNAVCPTPADFASMPIHWPPALQELLPGPARVLLARQQAKIERDWAAASKLFLSPSTPSASYSSSPSSSALDVVVNGVNGGGGDDDTNNIVKTNDKEEEGKAEAVDDANANLLKQKFVHAWLLVNTRTFYHESPRLRRRAKEDRMVLQPVADLFNHAGSRTGWCHVAFDAASFTVRADRPYSAGDEVRICYGRHGGDLLLVEYGFVLGGDSDDDDNSNNNDCLEENCWDEVGLDDVLLPRLSDSAKDKLSEVGFLGGYVLDAGTVCYRTQVALRALCCLQTGREEEWRRFLEDGEDADAARQGEVDGVFVGMLEEYRAQTIGKTLAKVAAMEEEEDDAAPSEEGGGGPSSSSSSKAQRGAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYW4</accession>
    <name>A0ABR1VYW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666471.1">
        <property type="nucleotide sequence ID" value="XM_066814509.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047569"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539431" evidence="1">
        <location>
            <begin position="22"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="30177" checksum="D0C1712A3387EEEF" modified="2025-10-08" version="1">MKTTTILSSAVTASLWTLATAESTIRRDTIFGCTDVGCPPEKGSSISDNCTVADETHAFVGLTAVPAQVEPLRDGRLTWVKGVKADQKPNPDVFRETFYLGAAPGLEGLSRMGACAVFFNGPYNASLLKFNNSRERELDEGTCADAMGEPCVHALRERALSLSFAPGAASNETCRRLQEDLLTSDIPECSRWTENEWGNITAVASYVGITPILTLFWPTNGSALDRRDAALTCVKMMGPANASLATMKSGGGDDGEGGASTVWSTFTLNVAVSMAAAFALFNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W793</accession>
    <name>A0ABR1W793_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphoserine aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007178</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666835.1">
        <property type="nucleotide sequence ID" value="XM_066811493.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044553"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF4">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="4"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="339" mass="37879" checksum="1564CE5654E58F2A" modified="2025-10-08" version="1">MVVVAVAGGLGDLGHLITNALLDTGKHEVYVMSRKRIDDEAGRTSPVTGERYFPVIQTDYSSEDKLTAHLTEHNIQVVICAFIMDNDSVSDAQLRLIRAAERSWCVRRFIPTEFNVEYDAGDDTLPYPKKRFHMLARRELEEKTRTLEYAYVYPGMFMDYFGLPRVASVLRPLCFFVDPAHGQAVLPTGGGEAKMSMTTTTDFARYLALALDLESWPRVLSTVTSTVTLNELVRLIEKSLGRPLNVRYQPVEALLQHTGFDLPANLEIAAERWTERGGLDQLRALIADLEASVVLGAYDLTQLTGHLDLAKAFETTGPAPKRIEDLVEEAWGSKFLKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7J9</accession>
    <name>A0ABR1W7J9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hsp72-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007269</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666926.1">
        <property type="nucleotide sequence ID" value="XM_066811584.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044644"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="611"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="688"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="611"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="635"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="811" mass="89992" checksum="B3B8E421A42E3AD3" modified="2025-10-08" version="1">MTTYGVGIDIGTANTRVAVYRNDSFELIPDEEGMFSMPSYVSFGDRQRHIGATAKRQANKNPENTVFNVLRLIGRDFKDPTLQDDLNYLPFKSATWGRKCALPPEEVLAMILAKTKQNAETYLDATVKEVLLSVPADFGIRKYDAVRNAAAIAGLEVLDLHPSSVCASYVLGITRPEEEITYVMADMGAGGFNFSVVTSEESIHEVLGSGTGGEDVVKLLVRYFADEIRSSWYKDITKNKRAFQRLRGACEKAVCDLSSAQATEVHLESLVDGRDFVHRFTRQDFESISFLLFEGMRQVLDRALEDARITKSKVNYVFALGGCSRIPQVQNVLSDYFENKELDRFLDAEEAQVCGLAVGAAIKTDKQPNTRTIESLLLSVVPRSLGIETHSGRVQKILPKNSTTPTKGQATLSLSLTDFDPGISYNANGGKMKPDGDLAPGTRTLRFYEGEGAYTSSNELVGTLPLDAILPPPGPEMISLEVRLDVTSDTRVTGTVKVAGTVAYEKKMKEISISLGNHMPAQRLQQSITNEAYYRRADEKEAQRLAQRVELDQQISSMSEMCAVDGNLESRRPGLSFTIQSMRSWLEANEDATLNNYRAKLQELRDIQRKLQNGGTQAHTSRPSSAGDPPPQYQEEPNTASRTSVPLHVKGEVQEMIDWLDAVRTEFDVRHRKLQATLEAFQNMTNDERAARHGSGGAQGSSARPYQPPPTRDPAEVFESHFDGTKTCYTTADLQMISTWLRVQGQEEQSRNPKLYTVLRLVDGLDMFVQFIRHGISDASFPLDLKSLPSSIELEIALKFFDQQAVVTSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7L3</accession>
    <name>A0ABR1W7L3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007282</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666939.1">
        <property type="nucleotide sequence ID" value="XM_066811597.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044657"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clr5" evidence="4">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="698"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="851" mass="96254" checksum="B1D7AE00AEFBEE53" modified="2025-10-08" version="1">MAALPPSRPSLEWQPRDYTVWDANRDRIYEIYLVEKKGLRETKRLMEARHAFPEFDNNMWEHVLLRHFGFRKNLSKADWVPIGQSLAKRRRLGKNNHAIDLCGAKIPIRRVEKNVPRQVTLLADSPELPRDILIRTPPPDEPFASRALQRRVNMSDLPLASSSGVAFMRDMLPEWILEVRKNSPFNQTMHRLILSLESHFVTDNVLRQSFASLSQMYQMYPSPSKLGTSSSLDILSYACFSMSRGSYFGFPEPLPLLNWIRKIADLRFLQAIFSTNTPTLLELWSTILQVAWKFRNLDAFKSLTEVGLRVTNRQWARFCLDICCHCYCDMDERFLNQSLLSSTREVIESQWVSNDKRPSAHTLWDAAARYLDIDMMKILASLGYHFSELPAKEQQHCLQHVSGATAAPVLDDGIYWDGPHWPVLARDFAWVKGLEGRFQPSLLEEFSLRDDETVTASGIYRAASGGCASLKHYMETTPCPTIEVRAVLLEITLSQTTACGCCEVLDCLLDYGVDPNAPSLGRNKLAGPRHASLHCHESFISVLSQETEDSWIVTIKLLETFGLNPQRFGDSEVVQAALFESTIRRKQLIIRLLEIFKLGRELELVSLDAGTWYSMASQNAKMRDQFDCAASPNHSTRFFDLRGGGCWVRSRFERPRQSDNPFNASNFRQAFDMALGFIRRGADVNAAISYDLSGWSGKGYTALHFACISGAPLPFLETLLDLGAQVDAGSELGVPTSLCYAIAAGHLNIMSLLIAHGAAINVTVRDGDTNRSVWNLIPEITWSHLDLAAAMGDLEITQLLYDFGTRSACQVFTEVDGAVQVARRHRRLGVFRFFEERVEGLDRIPDRPELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7U9</accession>
    <name>A0ABR1W7U9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dipeptidyl-peptidase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007373</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667030.1">
        <property type="nucleotide sequence ID" value="XM_066811688.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044748"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF13">
        <property type="entry name" value="DIPEPTIDYL-PEPTIDASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="6">
        <location>
            <begin position="503"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="318"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="329"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8079555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="745" mass="82034" checksum="588788E113593867" modified="2025-10-08" version="1">MVIVPKFTPEILISAPRRAPAVPNRDGTLALFAQSTHTVGEDKTLKEVRVMKVESGDSQQLVADDKVHDAVWLPDGSTSPSAVIWLKKGDGGVTSIEMVADAAKPSASAVVKLGEIAAPVDNLKLKALKDGSVAFLVVGLADEEGALYNPEKHKKLSSIRIHDEYDVRIWDTYTKPQKHAIFYTTLAKSDEGAWKLSGPLRNALKGSHLDAPINIYEPDDPLAHFDTCEGGIVFAASPTRVKDYRHSRTSDIYYLPLESFNKDSTTGPRKIAVAGDDGGDAGPSYCFHPRISPRRQHDRLPALAVRAPAKGINLRAPARQRQRLDVRGRSRRSGRLRHRHGQAVEPDPSGLEFSTDGHFLYVDAEDCARHGLYRLDLQPNAEPRTLLRDGAVKAYYPLQAKDGDEGVEKVFVSSANIVEPSIYQIIEADPSAVAEPWTVSKASHLENLGLSRKQASEIYFEGGAGDYCVQAWVVKPRDFDPEKKYPLCLVVHGGPEAAWLDDWSNRWNFALWAEQGYIVVAPNITGSTGFGLEYTEGNEVNLDANINCPAVHDNWGGGPYDDLVNCLEFVKDMPGIDMDNAVAAGASYGGYMMNWIQGHELGRRFKAIVSHDGVYDVPTSCITSDYVDEDAEYGGPPVIWKNNDGLERYNPARPDLLPNWTTPMLVIHSDNDYRVPVTDGVAAFHTLRALGTPARFVSFPDENHWVLKPENSLQWHRVVFDWINRWSGVAERTAAVAAGTTTPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8M8</accession>
    <name>A0ABR1W8M8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007661</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667318.1">
        <property type="nucleotide sequence ID" value="XM_066811976.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045036"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="20"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="310"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8079843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="405" mass="46042" checksum="064438D6B501672B" modified="2025-10-08" version="1">MDALPLASGSSFSWLKPHARFVMIFVGPDEVPFAIQKDFLCHKSTFYRQYFEDKARNSDLEYVVTLPEVTPEVFGLVQNFLYTGRLLTSIDSLPGYELLIATWKLGHRLGIDGLCDEVLEAMAECRRLTQSIPATPLLVQVWNDTPEGSSIRKLLLNWAAEYIRSSESRSEFSKSLPQEVLSELVVAMSHLDSAPVIQLNNVQSPKDQAQQKNVHYLNADDSDDEPKDKAPKHRHSDVTSARAAPQEKRPVARKPARSSLPTLKPGRQRKSLVNTGGDHQFTDDQKLNFCSDLLSRMLSGPGFWTRLVGPFRQPVNPVEDGVPDYLEKVTKPMDLGTIKDKMDRGQYKGDEEFVSDVRQIFTNCFTYWTDKDPMWATCEKFQRTFEEKYSGMHKWILKMDGAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8Q1</accession>
    <name>A0ABR1W8Q1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA damage-inducible protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_007693</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable aspartic protease. May be involved in the regulation of exocytosis. Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds ubiquitin and polyubiquitinated proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DDI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667350.1">
        <property type="nucleotide sequence ID" value="XM_066812008.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045068"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05479">
        <property type="entry name" value="RP_DDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14309">
        <property type="entry name" value="UBA_scDdi1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01796">
        <property type="entry name" value="Ubl_Ddi1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033882">
        <property type="entry name" value="DDI1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001995">
        <property type="entry name" value="Peptidase_A2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019103">
        <property type="entry name" value="Peptidase_aspartic_DDI1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15397:SF3">
        <property type="entry name" value="DNA DAMAGE INDUCIBLE 1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15397">
        <property type="entry name" value="SODIUM-GLUCOSE COTRANSPORTER REGULATORY PROTEIN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09668">
        <property type="entry name" value="Asp_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50175">
        <property type="entry name" value="ASP_PROT_RETROV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="12">
        <location>
            <begin position="36"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A2" evidence="13">
        <location>
            <begin position="258"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="11">
        <location>
            <begin position="458"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="375"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="393"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8079875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="499" mass="54051" checksum="6FF07A1C85A53FB7" modified="2025-10-08" version="1">MYSSACQPAIDGIGIADIALYPSPFYHILFRRGRRITLNVNNPEVEESELRLLTLDVFPDMTLGALRSSIEAEGIPAPSQHIYHNGQLITDASKTLQELQISDGDMLALHVRDMRGNTGVAQPPPQQQPQQQQQRQQQAAAQQDPELVRLQFLGDPRLQAELRRRNPQIADALNDPTRFAQLMRQGNASQEDERRQRMREIEQLNRDEFNPDAQARIEEMIRQQNVMENLQNAMEYNPESFGRVHLLYIDVKVNGTKVKALVDSGAQATIMSPSCAEACNIMHLVDRRFAGIARGVGTANIIGRVHYTMLQLGSRYLPAAFTVMEGKSVDLLLGLDILKGHQATIDLSRNKLIIQGEEVEFLGESDIPRETEAALNEEPTVQGPGGTTIGARSGAVTGPSAPAGGAAAPAAAPSTTTAPASAPTPSTGPPASGSASTASSQAPGSAVPVPPPQRQPQQFPEEKIEKLMALGVNRQDAINALEATDGNVEYAAGLLFQNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAK8</accession>
    <name>A0ABR1WAK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667997.1">
        <property type="nucleotide sequence ID" value="XM_066812655.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045715"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047443733" description="Secreted protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="19424" checksum="A572C4489760E871" modified="2025-10-08" version="1">MRNAMSLMLLHAILIGLGVSQRLDVDLVGLVDLALSSVSDEDGLASPLDDDILALGDGVEVDLDLGHGQDIGGRGHVLQELCSRGLTRVSKPLAAQNGLAVEPQLHRLGTGGSNGTHGTDHEVGDEVVRADRVLGHVAAPVGDLGGLAVALEGAAVVAITERAGGRKGADGAEGSGLGGLSREGAMRWSKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB98</accession>
    <name>A0ABR1WB98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007246</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666903.1">
        <property type="nucleotide sequence ID" value="XM_066811561.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044621"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF19">
        <property type="entry name" value="DUAL O-METHYLTRANSFERASE_FAD-DEPENDENT MONOOXYGENASE ELCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="147"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="367" mass="40214" checksum="4AAE63048FF22E7C" modified="2025-10-08" version="1">MEKVARDAALEHTAQIRQLVHDPSSFLTDLHIQQQQYYSIQWLSHFNILSNIPLPPHETPYAAIAAMAAVPESTLRSVARMAMTAGFLCETPSGRVSHNALSASFVEDAHMRVQLEHMFNATIPVMAGLVKATERWGDSRAPNETAYNVANSTELPFFAHLKSRPELQKKFEDYMKSRAVSHTGSRVEHLLDAFDWAASGVTTVVDVGGSSGSTAIMLAGAHPQLQITIQDLAGPIANAQAQIAALPDQAPQQGADVYLLRTILHDWPDADAARIVRGLADAMAPASSRLLVMDMVLPKPGSGSGTHEAALRQKDLMMLGTFNAKEREEDEWVALFREADPRLRIRAIHRPTGSELSVIEVYLGQEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBT9</accession>
    <name>A0ABR1WBT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668378.1">
        <property type="nucleotide sequence ID" value="XM_066813036.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046096"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="108" mass="11728" checksum="EC4D4B1B95281348" modified="2025-10-08" version="1">MEHSTILGAEVVLPLLLYCLIIYILYPQALTVIPYYVDPAKRRQSDQPAVGVLYGRLHELLSPTMARSLALGSPVCGIRITTDGEMPSHPVLRPKLFGAPTGLSAKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBZ8</accession>
    <name>A0ABR1WBZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668504.1">
        <property type="nucleotide sequence ID" value="XM_066813162.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046222"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="612" mass="70996" checksum="D27CF9FF3D99CFE0" modified="2025-10-08" version="1">MTPWPDRSSTKKYQGNRKDLPEDEEVSMAPLLWVSALLSERFWSTEVSKHGAKALFMPKLVKTTRHYSTNGIRPNAIYRAETLLRIETPLDSLRDRLRTTALDFNARTLKWADRHPWYDEERYKWLNSPWRWADNWRWFIKQFKTAHAKKDEFQCYKYCEDMMGLYNRGTSWTWMYWAIGLLMKASMPVHRTERKQSPMNPNVTEPIRRTANTKNPFFVETLVRSQVAQGNPARHQGMHKRERSNYFQDNPVTIPPSEYTEPDAGAAKQRIRHQADWLKCYQSWSYAHERLDPLPRGWHDSLAETERQLEQARRDPAHADRRSWAPFDFKVPPYDDRWQAGDLVPGGGAMVRTIIDADAPALKPLAQLMETRGEELRKRLDEQAKVFLAKNVAGEPLPHLTVTEVGGHREADDAWVIYGQNNNTYNVYDVTAALKELKWTTQQYQEVTRTTDYGLEMRTGAHVQNVTAGNAFLRTFMRWKLLGKLMVPMLPEAVKENDGTGGMSLYKTCGKHVFDLTSFLCPPHWREILLSNPGGPINESLPGFYPEMISVISKHRCGYVMDPPTVPRPDADLTPFTERTLRVYDNPRSGLYYAVEGFVYDMTSTYIFSKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC49</accession>
    <name>A0ABR1WC49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008893</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668550.1">
        <property type="nucleotide sequence ID" value="XM_066813208.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046268"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052174">
        <property type="entry name" value="Flavoredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43567:SF1">
        <property type="entry name" value="FLAVOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43567">
        <property type="entry name" value="FLAVOREDOXIN-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="5">
        <location>
            <begin position="13"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8081075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="239" mass="26247" checksum="E5047DE75D69C078" modified="2025-10-08" version="1">MHSVITPAIMYWGTPVVLITTENDDGTANIAPISSAWWLGHRCVLGLAAASQTTINLLRTKQCVLNLPSDDMGSYINAIAKTTGSPVIPPVKQALGYEHCKDKFTRSGLTPHPSDLVQPPRIAECPVQMEAELAGTTELMQDMPDRKGFILAIEVKVIRTHVQDELRLPGHSNRIDPDRWRPMIMSFQELYGLAPKKTVSTLASIDEEKYRPLTVSNVGEPAAEKDKVGSEEAYEDAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC71</accession>
    <name>A0ABR1WC71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">H+ symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008932</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668589.1">
        <property type="nucleotide sequence ID" value="XM_066813247.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046307"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="69"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8081114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="494" mass="54609" checksum="B3E82B58F8F30FE3" modified="2025-10-08" version="1">MENNHGMPVHGEGARRNFEGEDPNYHPPHHGMSTGKYLATRFSSLKPAMAPAPNPIKLLRMLTMQNWAFFAVAFVAWTWDAFDFFTVSLTVEDLAEDFGKTKTDITWGITLVLMFRSIGSILFGIAADRYGRKWPFIVNNLLFIALELGTGFCQTYDQFLACRALFGVAMGGLYGNAAATALEDLPTEARGLMSGILQQGYAFGYLLATAFARGLVNTTPHGWRPLFWFGACPPVLIILFRLMLPETNTYKHHQEVRRIEGGNVGKTFIAEGKVALKRHWKLLTYLVLLMAGFNFMSHGSQDLYPTMLSNQYNFTPNDVTVTQIVANLGAMLGGTVVGFSSQIFGRRISIIVMCVLGGALLYPYSFVSNKGLIAAAFFEQFCVQGAWGVIPLGNLVSSASSTIESTIGERFPLPPKGTVKRYNYGIVICIFMGCVYAYVILLTFLGPEHLSKSFDVAQDSDMAEVIESKHHHDVGVHRRGSSVDEEKAVARQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEB4</accession>
    <name>A0ABR1WEB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TRIP4/RQT4 C2HC5-type zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668316.1">
        <property type="nucleotide sequence ID" value="XM_066812974.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046034"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039128">
        <property type="entry name" value="TRIP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009349">
        <property type="entry name" value="TRIP4/RQT4_C2HC5_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12963:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12963">
        <property type="entry name" value="THYROID RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06221">
        <property type="entry name" value="zf-C2HC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRIP4/RQT4 C2HC5-type zinc finger" evidence="2">
        <location>
            <begin position="202"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="504" mass="53778" checksum="4651C54C9835F9EB" modified="2025-10-08" version="1">MSVSQLSRLLPLPDEDLQQVLTYAATLSKPEAVEHFRNLLGDSPDAVDFISSFNSRRQDPKPAPAPQPSKKKAPLHTPAPRQVTNLGPAPGTAYNKKSLEDDYRSGASSRAASPAKPPAKSATPPPPKPPPSAAGHLISDLPKSKPKSTPASRSSTPAPKTKVNISGGTAMHGASSALSDLDAAIKALELTTNPTKSSDASRKCNCVAARHPLLAAAPNCLHCGKVICIKEGLGPCTSCGTPLLSSEEVQSMIKELKAERGREKQAADRGAHRRADVSRTPAPFTKPRETNEDLSSAEAKAREHRDRLLAFQNQNARRTTVRDEAADFDVTGAMAGTGGSMWSTPEERARELKRQQKVLREMEWNAKPEYEKRRQVVSIDLVGGKVVRKMAAVERPSSPVEEDIVKIVEEVPASSTFVSSNIGGGGGAFSKNPLLAGLIKPVFQPEGKGKGAELEGRKDRKTKWRRVQDNLDDNSEVILNGGAYGTQPSSGQPITAGGDEPDCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM34</accession>
    <name>A0ABR1WM34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">HAUS augmin-like complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_005842</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669080.1">
        <property type="nucleotide sequence ID" value="XM_066810157.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043217"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026243">
        <property type="entry name" value="HAUS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570:SF1">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25762">
        <property type="entry name" value="HAUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8084571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="35859" checksum="892D5A25416E5324" modified="2025-10-08" version="1">MSHLHPQTAIFSPSVARAAASAAKDWSYVDNWLRTKYAARSVPKFERNPDTLRALLALASHNEAVDEERDQLAQLEAAALNEVKAADAAKETLRQGQQQQQQHQQGVLRGELVADDILDAIEEGLTREGRTALDAMARMAVELGMAFPTSEALGTRYVDLQAKVFELEQTLDRVALLQKYLERESQAMDNFIHEIRGQEYRPAADLAKQNLDLQRQIKTMSAKLPEIGQHIAALEKSVAIPSLTVEDVKRDEDAYLDLLTTKKELDARVKTFAGLPPDVEAARVELEALRTQLRDATARRDTVFEGLVERESPLKTRRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN95</accession>
    <name>A0ABR1WN95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006287</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669525.1">
        <property type="nucleotide sequence ID" value="XM_066810602.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043662"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF881">
        <property type="entry name" value="FI07970P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="209"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8085016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="391" mass="43959" checksum="E316A8042618D38C" modified="2025-10-08" version="1">MSVAKLQLRTALGPVYRDVLPNPPRDCTTDEIPVIDLGPLFSDELPERQKVAAQIRKASVNTGFFYVKNHGIPDEIIAKCKEQGLNFMHQSTEQKNRISSRGHSKHFNGYTGSASTNISPTESIDIRESFSFRYSPELDPDHPQDISELPDDVKEGIQGEDFVWKGTAHLPDFKKDCVAYWASCLSLARKLVRSFALSLDLDEHYWDDKVTHPGADSVFNYYRPRTEQETKDEFVGLGSHTDLQLFTLLWQDNIGGLQILTKEGQWIKVTTLLENKTIANADTTKAPPIEGTIVVNIGDYMMRLCNDIYISTVHRVANESPLERVSMPFFFGLNFNCVEGVVPSCVSETNPAKYEPISAGEWVQRRFKQERKAFDEKAAPSIAPSAVVIPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNQ4</accession>
    <name>A0ABR1WNQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669650.1">
        <property type="nucleotide sequence ID" value="XM_066810727.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043787"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="503" mass="55115" checksum="3C949E63F20B77E9" modified="2025-10-08" version="1">MSDSANEPEAQGLLSWFTSDDGPSGWRLDVVTLLAVIGESSIGDHAQAITASTPTRPTRMPETRAKMTGVFSGTTLESVGFFANILHPLDEFQPFAFKKLRIQHADRDIVGGLRVPKPAAHKKGVISKILSKGGRISSSISDRSAQLPRTRADVESGTRGTTSGLQTSTGADADAPIQGIARRPTMRERVQDYMADPGTINNEKRPAVPPALWSPVHILSAFSFLLSIAIIIVAAIQEDGTAIFAVVFISIVSSIVGVASWWKPVLMSRSHTNKVPKGDVVIRTREGAFILIECTEEVARELYAGTEECNYRVGAKAYQVLMGIGTFLLMVSVILLGNCKWVTQVLIGASYVILNGLYWIMGLLPKRLFWDLSRYTCEDVTPEDSRDAAEHANNGREGVPSFTRTLWYVIRETQRTAWVERSGAAPSTAHWKAWLTEAEVAATQGRRNWTPVATKDDIMKLTESELEDRKKAQKGTTVPDPAEQVAPATEVQPRNQSREPGQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQU7</accession>
    <name>A0ABR1WQU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP-dependent DNA helicase CHL1</fullName>
            <ecNumber evidence="15">5.6.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">ATP-dependent DNA helicase chl1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Chromosome loss protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16 17">DNA 5'-3' helicase CHL1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">PG997_007064</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="15"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670302.1">
        <property type="nucleotide sequence ID" value="XM_066811379.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044439"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF41">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE DDX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 22" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="21">
        <location>
            <begin position="20"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="146"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="834"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="871"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="871"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK8085793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="917" mass="100083" checksum="937F57C38B6420C6" modified="2025-10-08" version="1">MASSNEGLDPDLDHVTDGIKKVDFHHPYTPYDVQEQFMRSVYDVLDTGDGQVGILESPTGTGKSLSLICAALTWLRNHKQAKFESSVEDAARDLKDEPDWVVDSMLRRKRDEVIKKWEEREARLETVRAREKALEIRTTKRRRLNDRAAAGSDADHEPDEDEWLLDERDEDGSLGGEASNYSKDTRALMEKLGMMPKRDAEEEDDGADQELKVADLLHLEDPFTAVAVHCRTTAPYISPSIPEAMISKDNPSEPEAVKHVPLSSRQRLCINPAVARLGSVQAINDRCSELQQSNSKSKCQFVPNPDKLAVTHQFRDHALAAIPDIEDMFELGKKLSICPYYASRTAIPGAEIITLPYPLLLQKTARDALGIKLEGNVVIIDEAHNIMDAVANVYASEISLSELRRARQMLGVYVKKFGKKLKGENRVMVAQVARVIDGLSDWLDGALKLKGDQGIVDSNQLLKSKGADQINLFKLIQYVQESKLAYKIEGYVAHTEQDPKKPAARSSSSPVLHTLVSFLVSLTNLSTEGRIFYNKTPITEGQAPDIKLSYLLLSPTHAFSSIASAARAVILAGGTMSPFDDYTAHLFPDLALSKVTTLSCGHVIPPSSLCVWTLASARPGLEFEFSFQKRSDKRMIHELGISILNICTAVPDGVVVFFPSYGYLEEVVAVWGGGADSTPPQQKQQPQNAAPPSVWSRLQSKKMVFRESKGGSSDDVLAQYSEAILGNGGNDPSKPASPQPKTNGALLLSVVGGKMSEGINFSDRLGRCVVIVGLPYPNINSPDWKARIEYIETTTTTRLLAPNREGGEEGPPPKMSKADATAQAKDAARDFTKTPACAPSTRASGAPSGTRATTRPSCCWTAASAPSASAASCPAGSGAAWPRGRRRRRGPGGTLGQLMGKLHGFFREKRKLESSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WR52</accession>
    <name>A0ABR1WR52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-dehydrosphinganine reductase</fullName>
            <ecNumber evidence="9">1.1.1.102</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_007169</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>sphinganine + NADP(+) = 3-oxosphinganine + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22640"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57817"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.102"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:22642"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.102" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670407.1">
        <property type="nucleotide sequence ID" value="XM_066811484.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044544"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08939">
        <property type="entry name" value="KDSR-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045022">
        <property type="entry name" value="KDSR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550:SF3">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8085898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="325" mass="34946" checksum="EC0FABE331BE7B0F" modified="2025-10-08" version="1">MPTTFEVRGRTAVITGGSRGMGLAVARQLAEKGANVVIVARDQAKLLESLSYVKEGASSNGNQRFHQISADLTSSSEAVRVLDEVATWNGGAPDIVWCCAGSSHPTLFIDTPVTEFSNQMNHNYFTALYMAHAALRQWLRSAEKSNIQPSKPAAPRHLIFTASFLAFYSFTGYSPYSPCKAALRSLSDTLSQEVNLYAAANPGEPKVRLHTIFPAGILSDGFEAENRIKSDVTKLLEAGDTPLTPEVIASRSIKGLESGQELITTDFQTGLVGRSMLGGSGFVDWLLASLLVVVMVFVRGDMDKKVRDWGAKFGASGMKTSDGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRW2</accession>
    <name>A0ABR1WRW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669652.1">
        <property type="nucleotide sequence ID" value="XM_066810729.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043789"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF54">
        <property type="entry name" value="PHOSPHATASE SPAC5H10.03-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="32362" checksum="886B2974F5747D32" modified="2025-10-08" version="1">MAPVIYLVRHAQGYHNLNKENEQLRDPDLTELGKQQCADLCKRFPFHDKITHLLASPMRRTIYTCLLSFAPVAEAGKVITALPDAQEVSLQPCDHGSDPAKLQAEFGDKVNFSLVPEGWNDKSPKSKYYPDPKLLAARARDARLWLRDLVREAGDDAQVVLVTHGGILHFLTGDWDGYSPTSGKFNLVTGAGVAAESTPLFPRSPKSRDIDLDMIGTGWSNTEFRSYEFADSKYEDPNASLRETKLSRRERRGSAIPLTETEQFQLQEAFSNIVRAELKEAKEAAESAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS56</accession>
    <name>A0ABR1WS56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription initiation factor IIB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General transcription factor TFIIB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006774</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670012.1">
        <property type="nucleotide sequence ID" value="XM_066811089.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044149"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20551">
        <property type="entry name" value="CYCLIN_TFIIB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF13">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="Zn_Ribbon_TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="8">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="360" mass="39027" checksum="C39F07201B6FD372" modified="2025-10-08" version="1">MAVASGAADANMMANVGGGASSQGGYKENLNEILVCPDCQINPANLMEEFSAGDMVCGDCGLVLGDRIIDTRSEWRTFANDDQGGDDPSRVGDAMNPLLNGSQLETGIAFGEGSRARELHRAQNRSQNDKATKGLLNAYREISTLCDNIEIPKAVQDSAKHIFKMTDDAKLFKGKPQEVIVAGCIFIACRQAQVPRTFREIFALTNVSKKEIGRTFKQLEKFLQGHRENNTSNSLLNPLDSYENTNTTSAEDLCGRYCSNLNFLMPHRMEKISKALAQKSSAVKNLAGRSPLSVAAACIYMASNLMGEPKSTRDIAAVAGVSDGTIKTAYKFLYAEREALIDPSWLKPKGAGDLNKLPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWS2</accession>
    <name>A0ABR1WWS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002558</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LovG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670491.1">
        <property type="nucleotide sequence ID" value="XM_066806873.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039933"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF3">
        <property type="entry name" value="ESTERASE DBAE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="14"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="259" mass="28887" checksum="A6C87F5C8A80206A" modified="2025-10-08" version="1">MESPEYLLKTRGLPRILCLHGGGTNAVIFRAQCRQLSLKLEPYFRLVYAEAPYASKPGPDVVSVYADYGPFKRWLRWLPEHPEVEERAAREAIDAAVRQAMDDDDEVASGPWVGLLGFSQGAKLAASLLYRQQIRVERLGKGSRDTTDFKFAVLMAGRAPIVSLDPDVFHSSMLGDWAPDLMDVVNEEHVLRLPTIHVHGTLDTGLPLHRELLEKYCSPETARVLEWPGGHRIPLKSTDVNPLIDQMLDVARQTGALAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWS6</accession>
    <name>A0ABR1WWS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">P-type Na(+) transporter</fullName>
            <ecNumber evidence="16">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">PG997_002564</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="16"/>
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    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="14" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 20" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
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        <location>
            <begin position="101"/>
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            <begin position="299"/>
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    <feature type="transmembrane region" description="Helical" evidence="20">
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    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="819"/>
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    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="846"/>
            <end position="866"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="897"/>
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    <feature type="transmembrane region" description="Helical" evidence="20">
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    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1027"/>
            <end position="1047"/>
        </location>
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        <location>
            <begin position="23"/>
            <end position="97"/>
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            <begin position="1"/>
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        </location>
    </feature>
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            <begin position="440"/>
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            <begin position="10"/>
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            <begin position="445"/>
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        </source>
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        </source>
    </evidence>
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    <sequence length="1102" mass="119034" checksum="222D9F9054AAAE8E" modified="2025-10-08" version="1">MEKNKEASPQHVSGQSNEPLSRPAHALSWEDVLSELGTDALNGLSADEAESRKAKFGPNELGDAEGVQPMKIIIAQIANAMTLVLILAMAVSFGIQSWIEGGVISAVILLNIVVGFFQEYSAEKTMDSLRSLSSPTATVVRAGRSQVVPSSQIVPGDIVEVKMGDTLPADIRLVEAKNFETDEALLTGESLPVRKSHTQTFDDATGPGDRLNVAYSSSAVTKGRARGVVFATGTCTEIGAIASALNRKESRVRPVKRKPDGRANPARYLEAYTLTLGDALGRFLGVNVGTPLQRKLSKLAMLLFGIAVVCAIVVLAANHFRSRQEVIIYAVATGLSMIPASLVVVLTITMAAGTKRMVQRHVVSGTNALIQQVRNLKSLEALGAVTDICSDKTGTLTQGKMVARAAWVPGMGTYTVETSDDPFNPTVGFISFDANKPADLDMKNNKNSQGGEAAASTNRKADPAHLLKASTTGLQQFLSVATLANLATIHESDGTWHARGDPTEIAIQVFAHRFGQNRLDLVGNDDDKTKEWNDVAELPFDSDVKRMSVVMRENSTGKNWVFTKGAVERVIEACTRYTDSEGGALRDITDADREGILRNMEVFAGMGLRVLALASRPSDDKDASVRRSGGGGEKGEGEGDNGGDEIDRATVERDLVFRGLVGLYDPPRAESAPAVRSCHEAGISVHMLTGDHPETAKAIAIEVGILPSKTGRLSADVAAAMVMTAGQFDALSDDEIDRLPVLPLVIARCAPSTKVRMIEALHRRGKFCAMRADVGIAMGQAGSDVAKDASDIVLMDDNFASIVSAIEEGRRIFDNIQKFVLHVLAENIAQAGTLLVGLVFKDASGLSVFPLAPVQIIWVIMVTSGMPDMGLGFERAVPGIMQRPPQSLKTGIFTPEFLVDMVVYGLWIAALCLATFSLVVFGFGDGSLGENCNRDYSASCDTVFRARATTFATLTWFALFLAWEMIDMRRSFFRMQPGSTRYFTQWARDIWRNQFLFWAVLLGFVTMFPALYIPVLNHAVFKHTGISWEWGVVFVASALFFAGVEGWKWAKRVYFRRAARRAQGAVWKDIDVEQRAFGAYLTESSSQGLDPETAAGSPTGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXY6</accession>
    <name>A0ABR1WXY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_066807301.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="86" mass="8686" checksum="30F5AC7A849C88F1" modified="2025-10-08" version="1">MDTYKRPGRGGAGNYYSPQQIEEATGKGAAGGGGGGGGEQDLEAQKPAALHDDPPPPIPPPSRSLRLPSPPPVDMRDRAGAAPGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYK1</accession>
    <name>A0ABR1WYK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003202</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_066807517.1"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF26">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_4G05870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="297" mass="32348" checksum="C89816F2277A7ABA" modified="2025-10-08" version="1">MSSNEQFQSGWLPKPTDQEFPGKEGKLPVEAQYDTLPDYKGGFQKYKAAGKLQGQRAIITGGDSGIGRATAVLFAQEGADVLVAYLPAEQKDAEETKKMVESHGKKCHLFPADLSERSNCQKVVDEAVKLLGGIDILFNNMAYQMMVPEIKDLTEDQWVHTFNTNIHPFFYISKYALPHMRPGCTIINNASINAYIGRPDLLDYTSTKGAIVSFTRGLSNQFVHKGIRVNAVAPGPVWTPLIPATMNEEAQKQFTAPQGRPSQPSEIASCVVFLASPDSSALSGQVIHCNGGTIVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZD5</accession>
    <name>A0ABR1WZD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003472</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671405.1">
        <property type="nucleotide sequence ID" value="XM_066807787.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040847"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF72">
        <property type="entry name" value="OSMOSENSING HISTIDINE PROTEIN KINASE SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="573"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="1089"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="240"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="1140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8088511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1211" mass="132453" checksum="02B727739FBD46A9" modified="2025-10-08" version="1">MGRLSEVAREREVVRYASHLYEIAHKPQLATDPPCEPLPTTCADPVLTGLAQLGALRLDATRCLISIFDRTHQHVVAEATSNSALAPGNRGQNLWLGGIAIPREQGVCEHVLVPDSDAGETSSDLPILCIPDLQADPRFKNFSHVENTPYNRFYAGVPIKSPKNINIGVYSVYSDQPRGLLDDAQAQVLRDVSQTISGYLESRRSDENLKRSDRMVRGIGSFVDGKSTISKWWLGANTGPTPDIGAPVTIRQPQNRRGSDVSPHSRETAPPRPHPSPLQPSFPGGPFDPAKSDDSITSSASLGAPATITKTKSNVLVSSPMAKAPADDGHTLEVKDVFAEAASTIRDALEVEGVVFLDAVIGSFAGLVPGGKQHSANSSIDSTVTTPGEEGFWKILENYEGQCCKVLGSSTSDDRTGDKVSAGDHRIDIPERFLKTLLKRYASGKIFNLEEDGSVHVADSSDGEWAWYARRDSVAFPSPLERSSHGAHSQQYEGKALSAIFTGARSVAFIPLWDSGRERWSSGCFVWTKDPARVFTVDAELSYLRACGMTIMSGLARVDTMMAEKAKSDVLNSLSHELRSPLHGIVAAVELLDGTDLDAFQGEVLHSMECCGRTLLDVMDHLLDYSKINKFMKDSKDQYKKGAQLPKMKNGIQESFETMSRKKSLSFSSKMTNLSTDIDLSLLTEQTIESIMSGHNFQKMSIPTGTSHVEAFGQHSKFANPMDIGSDTPSVYLDLDPIHEISCRTEAGALRRIIMNLLGNSLKYTTSGYIYVSLRKQDPNHVLLVVADSGKGISDDFLHHHLFSAFSQEDALNPGTGLGLKLVQQITKVLGGSIHVESQVSRGTAVSVTLPLLLPYGTVDRDSVFRERIEKIRGLRVSLRGFKDTAETVGLPGRTPPSEMYLMEALCRQWLHLDVVKPDSRDVQPDIIMCTDQSLNELAIEGATATLPPVVVVCHDSLAAHRHAIVQRKGKEKNVLEFMSQPAGPRKVAQALVLALSRWNATSPSKHDLPITPPDSASWSDLGSRRGSLLYSSPSAQLSRTASFSEERRFCRGPQQLEVLTELEISRTSSNGSPINDQNISQPSAQNIKYLLVDDNKINLQILVSFLKKLKKPYATANNGLEALEKYMASPGDYRCVLMDISMPIMDGLESTRRIREFEHTKAQRPATVIALTGLASEDVQREAYASGIDVFMTKPVRLKTLEDTISNIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZI5</accession>
    <name>A0ABR1WZI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671440.1">
        <property type="nucleotide sequence ID" value="XM_066807822.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040882"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790:SF4">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="1">
        <location>
            <begin position="62"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="183" mass="20746" checksum="15E508EF25B88DE2" modified="2025-10-08" version="1">MDVAKMDVVKKALGWFDMPGEVRNMIYRDLFIRPDTFEIVGTGLIGNRLYPLLVGAKGDKGLSVSLLRTNKRIYAEAVGILYGANTFSFPCLPEYLRSFFDTINKANARLMTHVILPAEHAASYFASDRIGPEHPIFILVKHCQGLRELLFDTIITVQPWRKDRAPNWNPYTPPTLAYFVQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZJ0</accession>
    <name>A0ABR1WZJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide hydrolase</fullName>
            <ecNumber evidence="3">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671426.1">
        <property type="nucleotide sequence ID" value="XM_066807808.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040868"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03880">
        <property type="entry name" value="M28_QC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037457">
        <property type="entry name" value="M28_QC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040234">
        <property type="entry name" value="QC/QCL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283:SF2">
        <property type="entry name" value="PEPTIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044981017" description="Peptide hydrolase" evidence="3">
        <location>
            <begin position="29"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="4">
        <location>
            <begin position="123"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="375" mass="42560" checksum="0464C8475A2DDA81" modified="2025-10-08" version="1">MMQQSRPSSRGHLLSLLALQLLFALTIAYQTLSDDFLRNLTLAESDFDIHNQEGLLAPILIPRVPGTPGQAKTQQHFVNFFRKELPDWTLLWQNSTGTTPVTGSRQIPFSNLIVRKEPPWTKPGQANYLTLVAHYDSKFKPDNFIGAIDSAVPCAILMHIARFVDKYMKQMHEEMVALGELGGTVPMDMGLQILLLDGEEAFGSSWTSTDSLYGSRALAEEWEHTMNPALSSYRDPLSQISLFVLLDLLGSANPRIPSYFLPTHWAYKNMASVEDRMRKLDLLETKTKRPFLYEAGKVPDQFNPSFVGDDHEPFMKRGVPILHLIPSSFPDVWHTLQDDGEHLDMPTVRDWCKIVTAFTLEWLDMMEIVPEPEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZP4</accession>
    <name>A0ABR1WZP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="14">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_003609</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">NADH-dependent reductase for DPH3 and cytochrome b5. Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1. By reducing DPH3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 Fe(3+)-[Dph3] + NADH = 2 Fe(2+)-[Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71231"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:71232"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="14"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671542.1">
        <property type="nucleotide sequence ID" value="XM_066807924.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040984"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF184">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="9 14" id="KW-0520">NAD</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="16">
        <location>
            <begin position="61"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8088648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="310" mass="33900" checksum="A1109FEA0F53D56C" modified="2025-10-08" version="1">MSDESLVSSRNINGIYIPAGLLVFGTFIVKREWVPYAVLLALALGAWKFIDQQPKKVLKPDAFQEFELKEKTIVSHNVAIYRFKLPAPNSIIGLPIGQHISIGAHIAQEDGSSKEIVRSYTPISGDHQPGYVDFLIKSYPTGNISKYMASLAVGQTIRMRGPKGAFVYTPNMVRHFGMVAGGTGITPMLQVIRAIIRGRAAGDKTQVDLIYANVTESDILLKEDLDSLAKEDSGFRVHYVLDKPPADWTGGVGYVTAEMLEKWLPKAAPDVKLLICGPPPMVSGLKKASQSLGFEKARPVSKLADQVFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZZ6</accession>
    <name>A0ABR1WZZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pep3/Vps18/deep orange family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003689</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endomembrane system</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671622.1">
        <property type="nucleotide sequence ID" value="XM_066808004.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041064"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16462">
        <property type="entry name" value="RING-H2_Pep3p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007810">
        <property type="entry name" value="Pep3/Vps18_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058919">
        <property type="entry name" value="Pep3/Vps18_RING_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF26">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05131">
        <property type="entry name" value="Pep3_Vps18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26148">
        <property type="entry name" value="VPS18_RING_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pep3/Vps18 beta-propeller" evidence="9">
        <location>
            <begin position="28"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="623"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Pep3/Vps18 RING C-terminal" evidence="10">
        <location>
            <begin position="858"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="813"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF26148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="965" mass="108304" checksum="B76CABC42C346EF7" modified="2025-10-08" version="1">MALDGSNGFAAPDGAGMLSDLTGEAGLPIFEVERVQLQFSIAADFVAAQVANNVLVLALSNGRILRIDLNRPEDIDDIDLPKKPSEVGVIRRMFLDPTASHLLICTSLGDNYYLHSQSRQPRPLGRLRGVSIESIAWNPSLPTASTREILLGASDGNIYETFIESTNEFYRKEEKYLKVLQKLPDGPVTGLWVDNLGGKSDVRRVVISTQTRLFHLVGRVGRGHHEGSGSIYTKLFDAEQPVIHELSRSPTAAPSALAVTPDSPDVKSYDDVAPDRAFAWLSSHGIYHGKLLTVPAAPELGNKVLADSKLLPRSQIVSSKRASAEYIEAAILTQWHMVSLVGRRVVANNRLTGSTVYDQTILEQGQKALGLYVDQQKNTFWLFTAQEIFEVVVRDEARDIWRIMLERQSFDLALQHAGTLAQKDAVAMASGDYLASKGLFVEAAGVYGKSSKPFEEVALTFIDNNQSDALRKYLITKLNTYKKSSTMQRMMVATWLVEVFMAKLNTLEDTIKTEAELVEHLNTDQSREQLTSVRDEFHEFVSRHKSDLDRKTVYDMISSHAREEELLFYANAVNDYNYVLSYWVQRERWTDALDVLKKQTDPEVFYRYSSVLMAHVGHDLVEVLMRHPDLQTRKIIPALLDYNQNFSGPLTHNQAVRYLLYVINQLNSTDAAVHNTLVSIYASHPSKDESKLLEYLKAQGDEPGFDPDFALRLCIQHKRTLSCVHIYTNMGQYVQAVDLALSHDDIDNASDIADRPMWNPALRKKLWLAVAKKVISQSSGMKTAIEFLKRCDLLKIEDLIPFFPDFVVIDDFKEEICNALEDYSRNIDGLKKEMDESSQTAANIKVDIAALDHRYAIVEPGEKCYVCSLPLLSRQFFVFPCQHAFHSDCLGRKVLEQAGVGKSKRIRECQVKISKGLVNGAEKDAMVAELDALVASACILCSEYAIKRIDEPFVGPNDNRNEWAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X030</accession>
    <name>A0ABR1X030_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003744</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671677.1">
        <property type="nucleotide sequence ID" value="XM_066808059.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041119"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF170">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="84"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="55146" checksum="143679097A3D9067" modified="2025-10-08" version="1">MPVTKEDLQRIATAISYEIPEQDVDDFTTLLERARQTFETVSAMDDYQPTPDFNLTPRLDVHFPEKAENALNAWAWRCSCAHTSPSSTTLKGKTVCLKDNIALAQVPCLLGTESFTGWTPKTDATVATRVLEAGAEITGKAVCENLSRGAVSVTAATGPVHNPFARGYSAGGSSSGTAALVAAGAVDLGVGCDQGGSMRIPAAMCGLYGFKPTFGLVPYTGIASNDASVDFVGPMTRTCLECATLLEVLAGADGLDDRQGAGCPFPGQVPCYADELRASGADGAKGLRIGILKEGLEGAAMNDAVKAKFLAAAKVFIEKLGAAVVEEVSVPMHTSSRAIYSVMSKMGNHMGMLGRATGRRQVMLTDLAERKGLPYTQDALSKMSAFSHEGLLAGELGWSEYPLAYGKAVNLMRRLRDSYDTALRQYDVLILPTTLRAAFPLPPADASPVAHMEAGRGMTENTAGFNGTGHPALAVPVGLVPSEADPGVMVPCSLQIVGKFWDEATILKAAHAWEQAVDWKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X065</accession>
    <name>A0ABR1X065_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671707.1">
        <property type="nucleotide sequence ID" value="XM_066808089.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041149"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="555" mass="58159" checksum="C91C6C356A7A13AE" modified="2025-10-08" version="1" fragment="single">MSSNSGLSRTRSLRKPAAINAGSTNQKENTKLAPSSSNDLGGKGSPSRLPQVKPLTRAATTTATTSTSTRARTTNPTRTSAASAAAPPPSTTGRTRPLSSVPGSRNGLATTRRASPTTAENTAAAARPLGRTPSTRPAPPAPSASANIRSVSRESSASTQRPSSSGGASSTSTLTRSKTLGLGHARAKSTATGLTAATTLKPPSSRVSTSASSTVSAKPQTRSQTLQARGATHRASASTSSATAAAAAAPPSLPAGSQSRPAFNTNQQHYSPLKSHAPKPLTSTFLAPPSPSKLPANVAITAETARLQTELLQLSLLHRDAGATAAEWHESAQRKLGARFGGAEARNAAVLVRWGAARASTEVVGGLEEKVQMLDQVVNGVWRFGEPGGRYARVVEEFEDWAGRLQGIMEARRKGDVNSLLGNGLDDTDEVLFIGDLENRWRDECPGLVRKLEEWRRMLRHLGPVPDGNGDAPAATSTEDEESGGGGQKSSLARILEGCTSMVDDMLAELALMEQMVREAVRAEDDWIEAMNKELNLGKETDSQGDRSAPLWKMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X074</accession>
    <name>A0ABR1X074_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671638.1">
        <property type="nucleotide sequence ID" value="XM_066808020.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041080"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="69" mass="7342" checksum="58FAC6D69DFE6FD9" modified="2025-10-08" version="1">MPTNKKTYRVSAEGVALGIVMVAAGAVFLAVTWALVTGAKRCQDPSSAALSPYDVNLMDLRELRGRVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0L4</accession>
    <name>A0ABR1X0L4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003893</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671826.1">
        <property type="nucleotide sequence ID" value="XM_066808208.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041268"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="426" mass="45238" checksum="E2B42A845169D80F" modified="2025-10-08" version="1">MGGDGGVNNSTAPTRSPTQPPRRNDGASTYEFTGVNRQARSSGRDVESWVEVSSHPSSSSVSSAGDEIVTTGLRVGSSAYAARRRRLHPQSYNHLYVQQQQQQQASRAVQSSQAGTSSQEEYEESETDSDPVITSSTENITSVHIPGTTPLRNVHHAAPETSDEEEDDDDHATALGTRRPSEPFRPQPNAFSHPPSHLQHRHSTSSSIPQNHPRPSFSQRSSTARVDRRAPNLMSPSYQADNDAALRASLTTLLSCAAAARGRDKDGDKELGDRTDAGNQPMNLRFGRVLRADPAPTASGSSKEAAPGSEKGKRAATPTPPSKQPRAVKKKKTASSNVEDTLISPTLLTWVVSAGVVVLVSVVGFGAGYVIGREVGRQETLSNLGVGNASTAVTEGGSCGREVIRSSGGTLRRFRWGSVVGKGVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0L9</accession>
    <name>A0ABR1X0L9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADH-ubiquinone oxidoreductase subunit-mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003932</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671865.1">
        <property type="nucleotide sequence ID" value="XM_066808247.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041307"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="entry name" value="Cytochrome-c3 Hydrogenase, chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004739">
        <property type="entry name" value="PRK06075.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="HydB/Nqo4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH-quinone oxidoreductase subunit D" evidence="7">
        <location>
            <begin position="185"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="455" mass="51409" checksum="083961CE3C16D99D" modified="2025-10-08" version="1">MPSRSMSVSSVRPFSHSVFRRASEASTDRTTIQPVSNDFSDPYGVKHIEGPDGRTYEKSAEGTVEERKIRHYTVNFGPQHPAAHGVLRLILELSGEEIVRADPHVGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMTNEQCFSLAVEKLLNVEIPERAKFIRTLFGEITRILNHLMSVLSHAMDVGALTPFLWGFEEREKLMEFYERVSGARLHAAYVRPGGVHQDIPVGLLDDIYQWATQFGDRIDETEEMLTDNRIWINRLQGVGVVTAAEALNLSFTGVMLRGSGVPWDIRKSQPYDAYDQVEFDVPVGVNGDCYDRYLCRMEEFRQSLRIIHQCLNKMPAGPVRVEDYKVSPPPRAAMKENMEALIHHFLLYTKGYSVPPGETYSAIEAPKGEMGVYVVSDGSERPYRCHIRAPGFAHLGGFDHISRGHLLADAVAVIGTMDLVFGEVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1H8</accession>
    <name>A0ABR1X1H8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA endonuclease activator Ctp1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004247</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672180.1">
        <property type="nucleotide sequence ID" value="XM_066808562.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041622"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013882">
        <property type="entry name" value="Ctp1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08573">
        <property type="entry name" value="SAE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA endonuclease activator Ctp1 C-terminal" evidence="6">
        <location>
            <begin position="586"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="75"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="272"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="362"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="146"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="690" mass="77295" checksum="099BF08061D8073A" modified="2025-10-08" version="1">MESWFEDTGKPALFQAFTQVCSRIEKDFKDSVEAENHKKAELDAELQTLRVRAANVDRLEQQNKALKEELAQLKRSLQQDRSDAPGQENTSPSKSRFSRPPSGNTRVPLTPVSVNVRKSIKNEHADFTGLSHHEQATEYGILDGKYKRLRSQTADLVQANEKLQSELRERTKTTHSWKEYATKQKECAERRKGLIKRLKEELAVATNNVALDSSFTSDTNPNSPDPRVPDVAEAPEALRIRYSPSTEPSVQRNNNDLLRFGKSHIGLNGRIETDNHGGGQAVEEPGLPPMSDTRGCKFLDAPIKSEPSSDTPVVVSERPVRKRRHEDKSTNNGSAVTRVKTEEGSDPAVMDEQRHFVPHESIDFDDGENLLSTPSRNARQAGAATTSARVYIPEDNLQDITESPHDLTSDASPPATKHVSMSAHVQRRAGPLSDKSVVSAPDDGNTTLLGGIASLAEDGDDNRNDTTERPGPTFLGTGRLDSLLKTASPEKQAIRPSRGTLPEKPRPIGFSIPRLRHGQHRLEMRDGTLWTEWRCSIQPMQKAPGTGERSKRYRKDSLRLRDHPQWSLRLEDFKINPKHNDGLDYAFSEVVRNKEDRLCLPGCVKEECCAPGYRGQARGQRLETGAIAFQSLLESWLGDEAWRLASMSEDEKEALWLKAKTQQNANEFGKGHRYRVPRASTPWVFQCRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1L5</accession>
    <name>A0ABR1X1L5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">B-type amino acid transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004242</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672175.1">
        <property type="nucleotide sequence ID" value="XM_066808557.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041617"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF402">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="526" mass="55908" checksum="1DC5D1BA82D76E23" modified="2025-10-08" version="1">MMPPSRDAQADATQPLLAGPREHVSENNNNSSSSSSSSERGLRADPKTTRGAFTPNLGAKEAFAIVVSIVIGSGVFTSPGVIDTNSPSPAVALLAWIAAGVLAWTGAMTMAELGTAIPGEGGVQPYLQYMFGEVYGFLAGWTWIVAGMPATLAILSIVFIESIFSAVGVTDQAETLGHKLLAISILVVINVANSISTKASTRLNNFFVFTKFVAIACIVGAGIAVVAIHLADKDKDVGGGDWYSKSWFAYRTTVAPDGSTVPWDDLSSWEILGHFSAALYGALWAYCGWDKAIYVSAELSSPARQLPLAINTAIPTIIGCFIAANAAYYILLPWSVVSSTDSVAVTAVGRLLGPAAGTVAAVLICLVVAGSLLGNAFVSGRMTVAASRKGWFPRCFSMLGSVGLRPKETVDPSSSDAPLNATILSTILTSLYILFGNFRDLLTFAGLGDNSWFFLTVLGAIIFRFREPDLHRPYKPYMIIPIIFCIVSGFVVIRGAIFAPFLAMVEVMVWIIGFGFFRLQKSRNAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X226</accession>
    <name>A0ABR1X226_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672319.1">
        <property type="nucleotide sequence ID" value="XM_066808701.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041761"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="88" mass="9386" checksum="9A927F5297E3ABB9" modified="2025-10-08" version="1">MPRVVPKQIPWVVRRLPAAGPVSGSSSNNGVQADRASKPRLGGQMDSTASLNASLSEQSMTGSSVYGGTSSFQEGRYLSPHNLFRHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X282</accession>
    <name>A0ABR1X282_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672422.1">
        <property type="nucleotide sequence ID" value="XM_066808804.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041864"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="597" mass="65044" checksum="DADA6ADA5F55B771" modified="2025-10-08" version="1">MSLQSVYKQFLAAPNSSLLATDATLHYITTTTTFKTAADIIKHLSSQRNQIKKKKEDVLTAVEGDNVVVLEFDTALEFIISGGTYLPGLDDNFLADRTVVLPILHIVTFDNEGKIVQIRQSWDQGAMLKQVDVIGKTGRNWPIRDSQEQIKMITNAAKSVTDAVSAQKKADPVVRPRGEPNNSPLFGTREENNQSIASVISPRGGVKPKQRGFDEILGEEPAGTAAASVVSPRGGARPTQRTFHDIVGEESDNDEEGSPSSGRGRSRSPSKAIAPKAGVDKKFQPSRLFEKDEESEAARNAEAHARERSESPFKTIAPKAGADKKFKPSRLFESNEDSENDANTGKGPELFYRPNPKRFDHFEFGDGSDAPEAPDKSEPKPRDSKHGSQWSFDDFVTPQKVAPTRTLQRTNQDSRHWGSGDDVAEENEHPAQQRTRPSAEVHFEMQDDGTPVAPRQTVPRGASQNANSKLYKDRTTGEEDEDDASAEALGNITNLKNRNKTFGSQFAMSDASPAQKENQPTKPSNKGAAPGGRGIRIGGDGMGVPKAQTEIGCLVTAAMKSPSQPNPCLGGPIHDDDEVFHITFHGAARLRTPTYEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X283</accession>
    <name>A0ABR1X283_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7892 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672423.1">
        <property type="nucleotide sequence ID" value="XM_066808805.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041865"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057214">
        <property type="entry name" value="DUF7892"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25422">
        <property type="entry name" value="DUF7892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7892" evidence="2">
        <location>
            <begin position="768"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="940"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1256"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="967"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1007"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1175"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1274"/>
            <end position="1297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1311" mass="146327" checksum="8F1058CC38F50FF5" modified="2025-10-08" version="1">MTTEINSGLGKPDDTSSSDILMTSEADVGGRSSSEQHRMIDAVGAASPTIVNHSSEANSETRKRKSSHDGHLAQTAEEPVKKAKVEKALTGILLQQSASPAGCHESERYPLPAEIWQHIFTFVSPRELGNLLLTNRTFHSYLDPSLTVNGHTTCPSVTSKGHLPKLKPDVIWQTSRRRCWPRMPAPLRNHTELQMWRLACCRKCQFCGKREPPSPVTANHKTRSGPGEHGISIIWPFAVSSCGPCLLDKSLKEIDLLLSSTPSLIIPALPSVLLTEEKNILSPGALQNVQGHSDVKLTKLFYTKHVEELKEEFATVKAMGLATAEEWLKGLDDRGKELRGDSSRWEKWESAGGVSQMRKTLCQMQVEPTQEEIQEMKAARRLEIERRAALLEPPLLPNVLAHIPSFQAALQIIQPLDNNAWELLKPRLLSQREDADVRASQDRRLNAHPIASQVKTEDRCDGHGVQRESKELVDKDWDDAQAPLRAKISEYADETIKNAWHNGHKVKKDSCPKFAADVLLYVRKRFYAEVAKDAVAARAAGKGPTHDPPEGPFTQKLTLENMKWLFEVKIKPLTESCRKELFLCNGCDGNSKAYGFEGVIQHYAAKHTSSLSQGNIVVYWRSEWPATPPFHPDPLSKSTATATGTPTSYPGIYQPPYPAQPPINNFPQPRPFPHQGALGYGAPYRPDFGAHQHPHYPQYPASQPPFSIPPSYNASYHTPFERPGISQQNMPPIIPSYQQQHHFPGPHEHNTVAYQRNHIDYGLYSEDKIRAQLDYLAFNSRDVWMALASLRGLPGNIRVSIVIFHLTKRYRSRFSESPPLAMFIDGLSNKKEMRPVRNTNWLQCKACCLHLDDGAEIELRTFSLPQLANHFQQIHVGPFQSAGAPFLDWTVDMIHVPDLSGLSNLSGMDAQKEAIITEAFPISMVPFSYGQPQEIRETIPEWVGTEGYPSTVTGTRHEGEHQAIPISHPPQPGAPLNPSPDYGARPSMTPKQESHGKSRDRKASSKEKRKGANHGNLKRKSNAKSNDIAAKMGRSSHDERDGEAEAEESRQEEAIRAMWAAERRETARLASAPGGLKEKRESPKNGGMTTVKKRAVEVSPLPMPTETEPGDDLFAGLESHLNQQARSDPNVAGREAISSRHPIDEPHRPVVLLRPASQALHSGFASYEQTSRSHLTGERGERVLRSPNAEGHAEESGIRRAQARIQYVETYELVRMRDAEGEYFIRRPVRREMDAAYAGPRRLEYRETGSPSLNYGHGSIALSPAHEPSPGSERIIRRPLREEFREPGSLHYQEYDPRLGSAPPNSEAPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2C7</accession>
    <name>A0ABR1X2C7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alkaline phytoceramidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004507</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672440.1">
        <property type="nucleotide sequence ID" value="XM_066808822.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041882"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187:SF3">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="36519" checksum="88D42433824A10F7" modified="2025-10-08" version="1">MDALFSLGIPYREPGLEGWWGEKTVTLNFCEEDYVMNHYVAEVCNTLTNALFIWLGYKGIRDCIKYSHPWIFFVAFMGYTVVGMGSTFFHATLKYPMQLVDELAMIYTTCFMCYATFSYGRSRSISAVLGVALTGLSYYITERYYRTKDPQFHQDAYGILTAIVVFSNMYIIETQVRPALRARQEKRAPNPAILPADAIVKQMWAMVITGLSIFLGGFLVWNLDNIYCQTITRWRRQIGLPFAMLLEGHAWWHVMTGIAYYYISWRVWIHRCLDGDEDKFQLKWPSIWRMPEVVAIQEVQNGTAVQNGKATKKHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X338</accession>
    <name>A0ABR1X338_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">OPA3 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004761</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OPA3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672694.1">
        <property type="nucleotide sequence ID" value="XM_066809076.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042136"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010754">
        <property type="entry name" value="OPA3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12499:SF0">
        <property type="entry name" value="OPTIC ATROPHY 3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12499">
        <property type="entry name" value="OPTIC ATROPHY 3 PROTEIN OPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07047">
        <property type="entry name" value="OPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="194"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="206"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="222" mass="25340" checksum="5A50C7567B8621A7" modified="2025-10-08" version="1">MVALPLFKLASLFLRHVSKYGANRIKHQAHDHPGFRRFAARYGQAIHQLNMRMSVALLRDPEAIARAKEKAEAPTVKTEEQIKKEEEFKAKHGFTASQARTNRPSNILSVWKRKFRSLPEAKAVDLFADVIGDAFILSVAMVLIVYEWWRSSQKPDHNAERIKELNAKLAELEEEREREKMRQESRILTLEQALRGFKDPKTKQPLLPPVPTATPTASPPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3F5</accession>
    <name>A0ABR1X3F5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein BZZ1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004855</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672788.1">
        <property type="nucleotide sequence ID" value="XM_066809170.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042230"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20824">
        <property type="entry name" value="C1_SpBZZ1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11912">
        <property type="entry name" value="SH3_Bzz1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035459">
        <property type="entry name" value="Bzz1_SH3_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020454">
        <property type="entry name" value="DAG/PE-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF21">
        <property type="entry name" value="PROTEIN NERVOUS WRECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00008">
        <property type="entry name" value="DAGPEDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="8">
        <location>
            <begin position="359"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="527"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="634"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="420"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="595"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="275"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="596"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="694" mass="76935" checksum="FBB24B61BBB08681" modified="2025-10-08" version="1">MAEVEAAPSFGAELKDGFKPANVWVANGIAWLDDIQQFFRDRSALEKEHSARLNALAKKYFEKKNKKSASLSSRADEHERYANDLVTKVADPLKFYSSKFEELRKRHVEYADKLEGERDSSYAGLRKTKGKYDSAKAQSNYQQQIFEMNNLKNTYLITINVTNKQKEKYYHEYLPELMDSLQDLSEFKTMKLNGLWTVAADLESSMLQQSNEQVGHMNQEIQRNLPHLDSLMYIQHNQGSWQEPADKAFEPSPVWHDDDTMVTDDSAKVYLRNVLNKSKSQLGDLRREVDKKRREVEGIKRVKQRIREGTEQKDEVQVVTQIFAMQEDLHQVDRKRLTAEVETSTITAAVGDVTLGAKNHNFKSQTFKIPTNCDLCGERIWGLSAKGFDCRDCGYTCHSKCEMKVPAECPGELSKEERKKYKSERQTAASTLLKPATGTPDHVAELPTLSRSNTMNSLSSGYAASANRSMSGSISVPPAPSEEAPPEPSGPRPSISTTRKSRLVAPPPAAYISELPGSSANVSATSKPEQKGKMLYTFDASGDGEISVPEGRDVTILEPDDGSGWVKVRAGYKEGLVPATYLEILPSAPTAIAPQHTGSSFSNRPTSTYSNSGSSIGTVGKKKGPAVAPRRGAKKLKYAVALYDYTAQTDAEHNMAEGERFVLVKEDPGDGWAEVEKGGATKSVPASYVQIEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3U3</accession>
    <name>A0ABR1X3U3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Alternative oxidase</fullName>
            <ecNumber evidence="13">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_005041</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="13">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the alternative oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="13"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672974.1">
        <property type="nucleotide sequence ID" value="XM_066809356.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042416"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01053">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.140">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002680">
        <property type="entry name" value="AOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038659">
        <property type="entry name" value="AOX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803:SF3">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01786">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005229">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8090080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="35902" checksum="310FFF51E06A800D" modified="2025-10-08" version="1">MDHQAKGAFGSRTANFATSSPVKETEHIRQTLPAWPHHGYTEQEMLDVVPDHRPPQTTGEWVAWKFMRFCRWGMDFSTGMQKEQKVDKANPTTAVTALKPLTEAQWMIRFLFLESIAGVPGMVAGMLRHLHSIRRLKRDNGWIETLLEESYNERMHLLTFMKMCEPGWFMKSFIVVAQGVYFNSLFLSYLISPKITHRFVGYLEEEAVHTYTMCIKQMDEGQLPKWTDPNFKIPEIAVKYWQMPEGKRSMRDLIMYIRADEACHRGVNHTLSNLNQKDDPNPFVSEYKSGRAPPRPAIRPQGYERAEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3W8</accession>
    <name>A0ABR1X3W8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial ATPase complex subunit ATP10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672994.1">
        <property type="nucleotide sequence ID" value="XM_066809376.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042436"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007849">
        <property type="entry name" value="ATP10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28106">
        <property type="entry name" value="MITOCHONDRIAL ATPASE COMPLEX SUBUNIT ATP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28106:SF1">
        <property type="entry name" value="MITOCHONDRIAL ATPASE COMPLEX SUBUNIT ATP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05176">
        <property type="entry name" value="ATP-synt_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="39391" checksum="A4FAD36B9D4D3740" modified="2025-10-08" version="1">MLNSRAMSLAPRRQLLCRLCQSRSFSTSYRWLAAEQPAATKKAAAAAAPTGGPSKPAAAAAAAAQAPLRQVVPPPSEQFAAAPRGYGKRVEEFTPVPLSRPIGMAYPPEEGQNTGIDERTWNQRRKEFSTMSSSARWSQHLERREELKEKFRRPYFRDWGNLQFHKGKTFYPPPRLFKGDVSLYFPNLYGRTLLKGRGSPQRDTTPTLEGKTSIISVFSGTWAENQAKSFAGAAQNPALAKLLEDNGDVAQHVNINVETDRLKHMLIRLFLGGIRQQVGEANWDKYFIVKNPLSDEIRENVGLLNGKVGYVYLVDSLCRIRWAGSGEANDEEREGLVKGLQRLIDEERKRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X464</accession>
    <name>A0ABR1X464_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673081.1">
        <property type="nucleotide sequence ID" value="XM_066809463.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042523"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="539" mass="59322" checksum="C0BDFA2950129A0B" modified="2025-10-08" version="1">MVGVPRSNACALCLSRRVKCDEIRPSCSNCVKYGADCPGYARGVKFVAGKHVVKSRARRGTVEGASRRQDMLPSEKTMPANFLEEGQEVGSEQIGGQARPQQRYLTSHEKLQSALAHVNAVSVTTPRDNRAQFIGTLMKSLEESQPESEMVVLGTWFQQTTAHLGQKPSLDRASCAFALQLLGRNHHDEGLLAQSRTLYGQSLGMLQQALNHPTEWKTPETLNSAMILCHFELFAGTATTSSWSTWMKHALGVGRLIQLRGPASFNTEWERAVLLSFRPIMSVMRHHGHNPSDTTTVGSAIYKDQVDLVDDYMQLLARVPSAVKNLYMLRAANQDAAAAAKKAATLGEAEVACIRHSMRYIRDAFEAWYQRILPFNPTPAEVPTQDPASIYTTVLHYESPWKGALHMGYWASLCIVHATLMECHQFSPADDEDDDSGKGGGYGVGAAAFEPLADRILRSIETVGEGMMGPYRCGYSIRIAYEVVDERTQAWIRMWVARFEKRYAATAVESYPSLREVFLPPASAVRGGGEGGDSGLMGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4B1</accession>
    <name>A0ABR1X4B1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005199</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673132.1">
        <property type="nucleotide sequence ID" value="XM_066809514.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042574"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF17">
        <property type="entry name" value="SEXUAL DEVELOPMENT REGULATOR VELC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="7">
        <location>
            <begin position="245"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="429"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="443"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8090238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="465" mass="51396" checksum="E3DC3D79C2CDF52C" modified="2025-10-08" version="1">MVDSMARPYNSWAHEPYSSNEAPYYRPDSSRQGQRLPPSSSFLSQTPPQSAPEARETVYKQSPYAVHPAAPAPAHHMTPRPLASPPERQVTNQSGHHPADIYARLSPTYSSGASDQTGDVPDQYRPPPQNFSSRVPPPLTPPMRQYRDMPHSYPHPHPPAPPLPLPPTQSSVHRPFPGPPGKDLRIQPPPHVMNSPSQPNTPWSPNPSSAGRPDRMKISQLVDSGPTTSSPRAASKRPEVSRATGPGRKSYRLKVRQQPMAARSCGFGERDRRVVDPPPIVQLFIDDPDASPEEVKAQLKHPFAVVHATIWNETGEQDCSAMPEDYRQQRRLMGTVVASPFVGNDEKGEEGCFFCFSDLSVRTPGSFRLRFSIMFLDPTNTAIGHRTPICAITMSDVFTVYNAKDFPGMQASTALTKRLKDQGCLISIKKGSEKTGGGHGRDDSDDDDDDDDEEGRGKKPKRQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4W4</accession>
    <name>A0ABR1X4W4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673338.1">
        <property type="nucleotide sequence ID" value="XM_066809720.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042780"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8090444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="413" mass="47367" checksum="B686DA412BA17C87" modified="2025-10-08" version="1">MASLLSSWTQGKFRAFPQSLRSKRPKYARLYNDDDATDLGQLHMRTPAQRRTWLQRLCATIFLIVIIAVFFATYYVFQPGDDRKANKSAAVHHHHSHSSEGGCRQLHVRREWRTIDAEEKWSYIMAVKCLMAHPSQFMAGTSYYDDFIYAHSKTGVYSHYAAAFLPWHRMYVHLYEKALREKCSYAGPFVYWDWTLDSANLSLSPVWDPNAGFGSNGKATPLLRNDDGDVRYCVKDGPFADTTRPWKALSSGHSHDVTMEPHCLSRHFTEPGDELLPTVHRLISPERVEKTLSQPDYEAFFADFEEGPHNAIPQFIKGGLFDVYGAECVKETDYPVFWLHHTQVDRLWALWQQRNPGKRLKEYGGPSSDFRHHHDEDGGSFMTDVLPMAGLADDDPVVEDVMDTAGGLLCYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X507</accession>
    <name>A0ABR1X507_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673333.1">
        <property type="nucleotide sequence ID" value="XM_066809715.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042775"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="142" mass="15972" checksum="ECA54C96B3670D4C" modified="2025-10-08" version="1">MSELPVPLPYFIFVTAPTLVGWLQIGAVPFIPERPYAAPPTLVTFAATWVAVVWLLLAPLVTILLLLCDFGVAVPAFVFATSLVQLYFSKKFFMLPRSDAEKNIRLEQRMEQRLEEKQETMPLRKGPHGTGGHYVWDGSHLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7R7</accession>
    <name>A0ABR1X7R7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673539.1">
        <property type="nucleotide sequence ID" value="XM_066806243.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039303"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047128462" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanovirin-N" evidence="2">
        <location>
            <begin position="21"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="69" mass="7924" checksum="8B1A64285230CAC9" modified="2025-10-08" version="1">MKLFSTTLDLLGTLTLVQGRFISTCRDTRMIDGGVEAQTREANGNYRFSRLDLNHCLGNRNGELVWRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8T1</accession>
    <name>A0ABR1X8T1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673806.1">
        <property type="nucleotide sequence ID" value="XM_066806510.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039570"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="124" mass="14227" checksum="4DDE0ECE848180C9" modified="2025-10-08" version="1">MLDHFEPFFSQDGLSAINARWDRAWSAGERDLLRRGFEERYADRLPRTFGCEAVIGGVLSNGVRDSMDMRLATLSMKACRDVVRFTVQVEFIPELYGLEHWGCSTTRCCASWAWLVSGVDRRIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8V5</accession>
    <name>A0ABR1X8V5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gpi-anchored cell surface glycoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673845.1">
        <property type="nucleotide sequence ID" value="XM_066806549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039609"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="491" mass="52528" checksum="9066405197612BAA" modified="2025-10-08" version="1">MNNGNLSRQSSNASMQSKPAPSVGSSISQRIKALEQMAGKEKEAKQAAGQAPAVAAARNRPTTPSAAFFPVRKSASIREPSVSPSVTDAAGSVKAPDASPEESREGSPDQSRTTKRDRSASVQSRLSVFEPPTLPYQSPMHLEAGQKLSRLPQGSCETVDNHSLKRPVSRDEHKAYDAANLKQSPIVVEHQKAEPAQEPASDSADAPLADAPTIVEQPKETILERRNSKLETENGTENKRRTSLSIVKGFIKDRRTSVSSHSNSVDNLGAPSPAASSRPASAHHSSSGSIARRLSMSSRRSMSRERDTPAGMSPSSISETDGKGEKQSTASRLMRRLSSSLSGGRKAQSPSISPTVAEEDDGVNTVAPPPPEPTVSTKPIINEESLVSSYLGDVNVQFPDNLLWKRRSLCLDSAGFLVLSALQGHAPTAKDRAVGTKRYHMSDFRLPYIPDADVQELPNSVVLDFVFGSGLQIACEDRAGQTMTLHGKPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X912</accession>
    <name>A0ABR1X912_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673905.1">
        <property type="nucleotide sequence ID" value="XM_066806609.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039669"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF118">
        <property type="entry name" value="CYCLIN, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="709" mass="77311" checksum="60A66E3F6E7F402F" modified="2025-10-08" version="1">MSSAISTIARPFVPPYLPSPVGYPQSRRLVPPPLSLKKVQETSVADEAALYSGGLRTPPAEDGMGTTYHHNPVLSSTYDSHVALARQPNSLVQASRPGMVLCDATLNQFSKNQAQQQQQQQQPLPHQHHYQTAPQHHQQNPPQLSQPSQQPHHASAVASVPACHSGASRHSTRPSTPSSTRSSHAHSEGGTVSRRESTMVMHSLRMPSCITSNGGNLDDFAALMTCFFWFENMETIQAAEGVKDRNPNAPIPPLSSYTRPDRAYKKWVNTILSTTQVTQNVILLALLFVYRLKSTNPKVNGSPGSEYRLLTVALMLGNKFLDDNTYTNKTWAEVSGIAVKEIHVMEVEFLSNMRYGLLTSKQQWAEWLDKLACFHEYCEKAELAERAAEMAAARRAMQPNLPSPTHRTFTSPLPSPTSILPNSSVLPSSMQSTPASVPAYSPSATMYNTNQSWPGQFQPTPAMSPLAAKPSLSFNGTRKRSVESTEVVEPAPKRVNRQSVVSMPPHARQLPSGGVDPARLPVPHLTLDTSQATSAAYVPPPNYSQGPVSLPPLGSGVRAMATVYPNATTWAPQAPLMATCGPQTPAYTAPSNYGTPTKRHSPRGLAVYGSSPLAESYAGHHTPMSNSPSVYLQQRNSPYKPLRPVNTLNYPPPSIPLSEYHLGSAQMHYQPLGRRNNVRTGIVPEFMPGYGSGRPTPMPATHALHHYHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X997</accession>
    <name>A0ABR1X997_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytoplasmic tRNA 2-thiolation protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002396</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674007.1">
        <property type="nucleotide sequence ID" value="XM_066806711.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039771"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019407">
        <property type="entry name" value="CTU2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882:SF14">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10288">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8092035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="40658" checksum="9A7C3D469AACE30F" modified="2025-10-08" version="1">MASYQSETGKVFQAAHAPQRYLLALSCAGASSTALLNLLHDNLARQQAPQSAKGVKGGKGGGQRVRFEIVVAWTQTQTEADAAWQRYQARYPSFTFHRIPLSSALSLRTKSIDWTSLPPLNADLTAPHEQLADLLYTRLATPSSRADVQRLLVRHLLMDAAVREGCDVLLLGTNTTALAELTLSETAKGRGFSLPWQVNDGPFQLPSFASYLSSGQGEQTTTTTTESEDEAPSKLSIYHPLREIFRSELQTYITLTTPPLTDLLPASNTSPRRRRRRRRLEINYPSVVANVVRTTGKLERPGGAAAEDKKSTTTTTADDTTRSHQKQCGLCGIVLDEAGDARWRGELGEQAPDVEERRGKLCYGCSRSVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9E4</accession>
    <name>A0ABR1X9E4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_002359</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673970.1">
        <property type="nucleotide sequence ID" value="XM_066806674.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039734"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="226"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="418"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8091998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="609" mass="66866" checksum="62C1DD07431A764A" modified="2025-10-08" version="1">MSKRTLEDVEDDATLARKKSKKAKKDKAAPVEESEVAAAPAEDAMDVDSEAKVEKKEKKEKKKDKKSKKDKKEKKRKAEDDDVEAEAETTSSVDAAVSNEASAVEEEVKPKKEKKEKKEKKSKKSKTEDADAEVATNGAATNGHDTNGAADSNSSYVQSASLSALPESEIESFLKANETNITDPLAEPGKALRPITEFSHLPKTTLTSKQPFKAFKSPTPIQSASWPFGLSGRDIVGVAETGSGKTIAFGLPLVEAVLKMPKPGKNEGRIRAVVVSPTRELAMQTAEQLEKLGEVVGLSTVCVYGGASKDTQRNLLRKADIIVATPGRLKDFLEEGSIQLGNAKFAVLDEADRMLDKGFEDDIKLILGQCPSKEMRQTLMFTATWPQSVQALASTFMKSPVKIQIGGNTAGDLQANTRIEQRVEVVDPRGKEQRVLQILKQQPKNERVIVFCLYKKEATRVEQFLQQRGIKVVGIHGDLRQEQRTRSLDAFKKGDMNVMVATDVAARGLDIPEVKLVLNVTFPLTIEDYVHRIGRTGRAGKTGLAITMFTEHDKAHSGELVNILRQANQPVPEELMKFGTTVKKKQHGTYGAFFKDVDMSKKGTKITFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9I6</accession>
    <name>A0ABR1X9I6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674072.1">
        <property type="nucleotide sequence ID" value="XM_066806776.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039836"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="64"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8092100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="211" mass="22964" checksum="D0F7F9B543C4962E" modified="2025-10-08" version="1">MRTAVREDASRIAEIHMAAFGRNAMLHAQFPTLAIRKGLQKCIKDKAVADINDPRMTVLVVTSSDGPESTAGAVVAFAKWSHPVLPGEDYVEPPWIWPEGTDLETLGAWIAKASEVESRSAVGGVPCYHLSFIGTDPNFGHYGAGRLLVQWGIQESNASGMPLYLESTKEAAPFYEKNGFTTGETISLPIRVNGGTDTQIYEEIVFTYCPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9U0</accession>
    <name>A0ABR1X9U0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000114</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674202.1">
        <property type="nucleotide sequence ID" value="XM_066804429.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037489"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051983">
        <property type="entry name" value="WSB_SOCS-box_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15622:SF2">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15622">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NACHT" evidence="6">
        <location>
            <begin position="79"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="570"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="612"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="654"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="696"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="738"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="780"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="822"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="864"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="906"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="906"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="933"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1095" mass="123055" checksum="AFE7378155954E6D" modified="2025-10-08" version="1">MMSNSVRDIQTDGPSRLQIGNTYYPEATPDPWLAERRLPDPRDDKARIKETKGGLLRESYSWILEHIDFRRWRHEENIRLLWIQADPGKGKTMLLCGITDELELHGLSSSQVSYFFCQATNSKSNNAAAVLRGLASMLLQQETRLLKHVKEEYQRTRTSPFNEGENAWYTISRVFKNMLEDPDLPTVYFVVDALDECEKDLPQLLDFISKHTTPRAKWLLSSRHNPDIERKLRITESRTRLSLELKQNAEQVSQAVDIYIQRRLSELEEIEQDEDLLQRLRHTLLSKANGTFLWVALVIQELQDVNSWDMEEVLMNIPPGLKRLYDRMMRQIQDLKRPDLEYCRRVLATTTVAYRPLQLEELRSLSGLPQKVFDITKVIKMCGSFLTIQDRIVYLVHQSAQDFLLGQSQIFLPDLANEHYRMFSKSLEDIKACLKQDVYQLQHPGTHIDHIATPDPDPLAGIRYSCVYWANHLLECRDTEAAKEVRKDNGPIDTFLREKYLNWLEALSLLKAMSQGVSAMLGIQNFVTAYSAALLFSPQSSITRNQYKRPAWVTQAPKVDRDWNACQQTLEGHRGPVTSVAFSPDGRLVASASHDNTVKLWDTATGQEKQTLKGHRGWVTSVAFSPDGQLVASASDDKTVKVWDAATGQEKQTLEGHGDYVSSVAFSPDGQLVASASDDKTVKVWDAATGQEKQTLEGHGDYVSSVAFSPDGRLVASASHDKTVKVWDAATGQEKQTLEGHGDYVSSVAFSPDGRLVASASRDKTVKVWDAATGQEKQTLEGHSDYVNSVAFSPDGRLVVSASDERIVKVWDAATGQEKQTLEGHSDYVSSVAFSPDGRLVASASHDKTVKVWDAATGQEKQTLEGHGDYVSSVAFSPDGRLVASASRDGTVSVWDAATGAKRQTTYIGNTSKGANQPEPSAKLSNYDWPPIDQEENDEEDEGGEEGEEDEEDEGGEEDEEGEEDEEDEPYGDEAEVRKRVGMYRDFIRDLDAYQWLRARLRRGFLMTPADPDILAEISQQIMHQLPRPRKVSRRTSSETYEASFQVEWNPQSFLDQQGYQEEPDDAIANAITLTGSTDDAQAASCAQYLPKPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBT1</accession>
    <name>A0ABR1XBT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000818</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674906.1">
        <property type="nucleotide sequence ID" value="XM_066805133.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038193"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="337"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="688"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="115"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="730" mass="80495" checksum="E29B58154EA16612" modified="2025-10-08" version="1">MATSSHNAFPRSPNPSTRSYDSSSVSSATSPKPPAQYLSSLMSTSSAFQPYTPGTASSVMGRDSLPSNDSVASTPGLSNAQLSANVQAQKRAYRQRRKDPSRNVKCQFTKETNRRMSSIKQVQDLEKQIERVRRENNTLKRLLNDRDGQMDLDVEGVDQLAIPIPEIGTEPKRRKRTAPLHDPSRARANVRNISKGLFKPPAPYRPTPMAAPPEVRLPSPPPRSVTEALLHSYYGAIHVMMPLLHWPTLQREVEEIYQGAGLQRMSASWLSTFFAILAGGSVFSSERHPDRIHQAAELLEISRSLVDPWNNDFSLDNVRTAFLTSLVLNELNLKSAAWSGLGTAVKMAQDMSLHLEVGAPSRLEADMRRRVWWSIYILDRTMSLDMGRPSLIHDADCDVTLPEAIDDHYLHAEGPVHPLNADSLTHSLHLEAPCLLRRRGYPLLIRTSPVARGAFPAACDPENPLPIPPHMLMPMAYLLSARLLLHRHNLAPTCPPDIRSNAIAQCSYTAAETAKLIARTNASLADTATALLTTHIFRSALFLVMTEQHELAGVCIRALKSIDIRRDVAVPCGRFLSLFLSAVANKRAEVAAYLPRSVPGFGAQRPPPAAAFQEALCRDEELLAYLSADLQGGVESAWVWVGAERDTMPAAASASGGIVRSENRTGLSAEDLRDWIGWDRLDGQLRGLATEDGTGAGTEHPKKQHTPERRLVCQPGAKRCQEEYGKNQHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBW4</accession>
    <name>A0ABR1XBW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000769</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CENP-W/WIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674857.1">
        <property type="nucleotide sequence ID" value="XM_066805084.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038144"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13732">
        <property type="entry name" value="HFD_CENP-W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052484">
        <property type="entry name" value="CENP-W/WIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="8">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="78" mass="8574" checksum="6559CB380C046BAD" modified="2025-10-08" version="1">MAPGQKLYPRATVRKIVKAHSKCNVSKNVDVMVFLDYVLFMQSLMKEAAIDSKQAGERGVSAKSIKKVTADTLAKFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDZ3</accession>
    <name>A0ABR1XDZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675688.1">
        <property type="nucleotide sequence ID" value="XM_066805915.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038975"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF13">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="472" mass="52738" checksum="4C6833885145E8CF" modified="2025-10-08" version="1">MSSPPSLESHDGIAKERGRVDVKQLEEKPEPEPQFSPREIQGRFDLLRGLGDAEMEKLGKRVLKKIDMRMMPAITMMFLMCYLDRINVSNARLAGMQEDLHMTDTIWNLGISAFYIGYLVGQLPGNLWLAKASPRWFLPCAMLGWSALYYLHASFDKSGIPVSYHCEVTSSWYTKQENPTRMAIWHAGNTISNIISGFLAAGILTTMSGVAGLHSWQWFFLIEGIASIVVALGALMLLPNYPHNTRFLTPAEREMAQYRVLCSNGGKEEGIGGTWDGVKEAVKDPFTWFFCLMHFALIVNTFDLGELTTYFIQAPPYAFAFAFSCAVAWSSGRRQESFWHIVLPILGSAAGCAVLISTTNVGARYFGLFLLISGTYNGLNLQLSWETTLKAALIAIANCISQVSHWFSPYFWPRAQEPFYRLGGGLVLVGCLLVVVSAGLAKWRATKLNRKMDEAEGWLKQGGSERGWRYVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEH2</accession>
    <name>A0ABR1XEH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675771.1">
        <property type="nucleotide sequence ID" value="XM_066805998.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039058"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="237" mass="26385" checksum="AEC61DE31472DA18" modified="2025-10-08" version="1">MAQAPLADAVMTADEAPTNPGHDRARPDPRQDIETILEAMRHEGWTDKALAQARKFLKSHFRSQRARKVPSSVAGSTPAIRNEVKRLKKKVNIYSCQHGPTWYKIQAYANPANIGILCAVISLWGGQVPRNLEAAYEVRGQKELVERVKNKTGLGGYRVGGGGPHAQPDYCPTTLMISRGRVPTAQFVSEPRELWELGYRFTLSDDGDGDMKNFAMAFVCPLKKQVKRKLREASRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQA3</accession>
    <name>A0ABR1UQA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660512.1">
        <property type="nucleotide sequence ID" value="XM_066819627.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052687"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="517" mass="57480" checksum="1DED3BBA29FF8203" modified="2025-10-08" version="1">MDRSVSFGITTVLLPGENASIVEEVMSIFVGNQFVSEQVLRTIGTLPPGENFFPSPIDGVTATTAATATGTGGHDHLFSTALLFYYPNEYTSYHRCFRSHQSSRPREFRPRCRSHRRDRDRVCRGRNAPRFRCRMALFKTEASPMATASVGIILSRKGRHAREACTHRHTGTPNSHNNSNIFQLDQFLLDARPDRELVAELRSLDRTVRRHVEEHYHKQLVQDDSNVNTEGLAQVLAKLGINNSINEDEDAQQQAPSATRLSSLALKPSTRFQALRHIIMRVAFGSTTLRSGSSISILPPFVAAFGRYLEESESEPGLQRGTSDGTRQGLDPDSITNQLTISTLLVFSTALTKWRQLSVYLLRHTQRSSTDQTRTPISPLTPSEDISTQQAQQLAVELNRFLAPFVAVAEDGDDDESDTLARYEQENDLREALVECATLGYVLFSQPAEYILLYSDGKKRVAAVEGGGGGSSVSREKIVVCPGLQRVRDEEGGGILRRRYSCARSWRQLSAILAPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQN5</accession>
    <name>A0ABR1UQN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hexose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_015445</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660644.1">
        <property type="nucleotide sequence ID" value="XM_066819759.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052819"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF31">
        <property type="entry name" value="HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="35"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8061224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="536" mass="59717" checksum="126B73E7C94A6471" modified="2025-10-08" version="1">MGSWPLLPRIGRGNILPFQAPNRYPKTRFNNIVVLMACTVFTAACQGYDGSLMGGLNILPQYHEYFHLTDSLRSLNIAINYTGGSLACFCWTWVTDTYGRRVGLFWAAAITIVAAILQAASVHIAMFCFSRVLIGFGNVASVITGAAYLAETLPWEQRAWGLALFDDFFYVGALVAAAATLVTFRLPSAWAWRLPALLQCVWGAVCIALLPWMPESPRWLIDQGRGREALVVLARINVPDGDVHDDLVRLQFRQIFQTIEYERNPMKYREMLANRGARKRLIITATCALFSMLTGNLIVMYYIGDVLDHAGIHDQELQLVMNLGLNATSLVVSIVGTFYVDKRGVKSATLVSTGGCAISLFALGVLSKFNDHTDTTSDDYAAVFCTFLFAACYAFGWVPVLFLLPAEMLYFRIRALGMSMFSLVVCVTGIWGNFVMPLALQRLGWRLWIMNGAWNLFFFAFVWWYWIEIRGKTLEEIDALFDGGKRSSAPDVAEVLAGSADVNWKEKLSTWMSHRFGRSEGPASSQDGRAVSGHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTD0</accession>
    <name>A0ABR1UTD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glucose-methanol-choline oxidoreductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660488.1">
        <property type="nucleotide sequence ID" value="XM_066819603.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052663"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF78">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="86"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8061068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="260" mass="28673" checksum="C4DE64899BD30E7D" modified="2025-10-08" version="1">MDLTKMIQDGDKMIGWNVMDVSCKLRPSQSDLASLGADYQEVWNREFESDKTKPLIMMSLGAGYSKDPSEVPRGQYYMMAGVGLYPLSRGSLHITGSALRDPVDFDSGIFSDPERFDIRTCRWGYKVSRELGRRMSIYRGEAAPCHPPFAAGSAARCIETDEPLGADAPALEYTAEDDAVIDQWLRENVETTWHSLGTCKMRPRDRNGVVDENLNVYGVAGLKIADLSICPINVGGHTNNTAMTIGEKAADILIKELGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU07</accession>
    <name>A0ABR1UU07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014506</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661008.1">
        <property type="nucleotide sequence ID" value="XM_066818820.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051880"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="311" mass="33716" checksum="5436E40288D26B67" modified="2025-10-08" version="1">MEEPEASKTLEGQLPACPCPGSGRGLPILSVQPCFTLGLPKPLFNRTPRGLGTREQLQENGKHVLMHDERSAKLPRPTKTKPSAIPVLFFCVDAALPVDLFVFSCSFPASSPSQSCRSHHPPVDRWRGAAPVPEFQQIKQSSLSARPRWQAGPPTHSSNPSLKVLLRLWLWCVHDPCLGQVQEQTLNATHSGRYQGVESIKASPFQHNLPEGQREGSPASAQSLLPPDIFTLARSTANGRIRTRLGTVSMAGGRPLSLPGLFGKRATGQNYHTGYTSLGPHVIKASPALVPIWRGAMDLDLIATPTHRPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV07</accession>
    <name>A0ABR1UV07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pectinesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661359.1">
        <property type="nucleotide sequence ID" value="XM_066819171.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052231"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="48"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="237" mass="27372" checksum="0D6405A4FCCC12FF" modified="2025-10-08" version="1">MKHHWITSDTPDYLLDKPSDTPDSDCIPTSTSSKEQPSPEMAQEERSFHLFPQLPLEIRQKIWRLSLEPRVLELHSRRTHYAQAEDWPWRSDCFNPALLSVCDEARGEALGALTVALPMPHGGMLYCDPMRDVLVVLGDSDLPRLRRLFAEVEDQDPRGLRHLALSVACWAHDYAGPTLRIWQRALFHKLDRLTLYLVLVDRFKQFRGRGDSWMVVGKAQIRIEELVFMAEDGSRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVI8</accession>
    <name>A0ABR1UVI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Homeodomain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_015004</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661506.1">
        <property type="nucleotide sequence ID" value="XM_066819318.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052378"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF265">
        <property type="entry name" value="MYB-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="89"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="1">
        <location>
            <begin position="89"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="1">
        <location>
            <begin position="137"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="141"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="2">
        <location>
            <begin position="144"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="21394" checksum="A377BEBADC42DAC6" modified="2025-10-08" version="1">MSSSGRKSPKRWTEDEDALLYHEYTRLCKSTTTAHTLPLSLIPHFCSFCTTGTADPNEITDWSRIAEGVPGRSNKDCRKRWVNKVCGGLNKGPWSREEDQRLRKAMEVHGSKWTRVSEEVDSRSADQCAKRWQQSLDPNIKHGNWTEEEDDRLLRAVEKHGRQWKQIQESYYQSRSRNDLKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UY04</accession>
    <name>A0ABR1UY04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_015028</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661530.1">
        <property type="nucleotide sequence ID" value="XM_066819342.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052402"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="4"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="155" mass="17473" checksum="061159F103C74BD8" modified="2025-10-08" version="1">MASTAHRRLLQEYRALTNNPPDGITAGPVSEDDLLQWEALIQGPEGTPFEGGIFPAELKFPKDYPLAPPTMNLPQRPRLHLHSAPPGDDPNHYEHASERWSPIQSVEKILISVMSMLAEPNDESPANVEAAKMWRDRRAEYEQKVRDGVRRMLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1K4</accession>
    <name>A0ABR1V1K4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011828</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661835.1">
        <property type="nucleotide sequence ID" value="XM_066816143.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049203"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF5">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="528"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="537"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="612" mass="67941" checksum="940C10A803C7BE60" modified="2025-10-08" version="1">MSFYRESTRPLLTPQNRRLRHLHGIYLRNLTFERHLFKTTDDVDLSRGSPNKLDALKNAPQLHHSASSDTLTQLSHRPPKPRRRSTNLANKSPVTRQKQLELAIESRAADVFFSLHIQGVDDPVYISEVGTRSTNFNFSFFELSQAGSHISRSSQVTVKVWAQRRGEWLLLLEELVDFRQLNFIGTLINHQFPPNCLVFHLIDGVYTLELPSRVPEPKRGPTLPTSSHNALMKLTNLEASIQDALATCESVTGQINTVLEQIPPDAVPEEEEKVKLVNKSLASQQRKMRAAEVRRDQLKASIAARRTAIIEGRAAQESVEQDVEHATAKLPASRDAISTTGDLIRGQRRRICEDLTHVFPITQVPSAPPLTFQICGLPLPNTNYDPTSSTASEDALSAALGYVAQVTHLLQFYLSVPIPYPITVYGSRSSVRDDISQIADTQRSFPLFLRGGATAQYRFEYGWFLLNKNIEALCVASGLKVVDIRHTLPNLKYLLYVCSAGTDELPERKRGGIRGLFAGKLKGRMSVDDMGGSSADGSRRGSTESDAAAKQREELRKALEGQRGGGGDGNSKLSAEVTPKRAPSPRAVEVPPFEEGLRVTLRTKGLRENMVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V231</accession>
    <name>A0ABR1V231_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662004.1">
        <property type="nucleotide sequence ID" value="XM_066816312.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049372"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045358406" evidence="1">
        <location>
            <begin position="19"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="113" mass="12240" checksum="B69107B4F73203C9" modified="2025-10-08" version="1">MYSPTLAIFALALSAVAAMPTNTTSPVPMSSAQADPRNKCSPNRVKSTVYTCAAHGKMTPVQCFAKVCANMDIPPHNGVSKRDVNIQCTDQNLFQCTIVEWRDAGDCIRTFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2J2</accession>
    <name>A0ABR1V2J2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012158</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662164.1">
        <property type="nucleotide sequence ID" value="XM_066816472.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049532"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF50">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="136"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="252"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="728"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="808"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="729"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="748"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="808"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="825"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="852"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="865"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="905" mass="100624" checksum="72FE128C9EB994CD" modified="2025-10-08" version="1">MTMDFASAPQTHTGSTPGSSVDSAIRDSMPVAPMHTMSGMGGGAPAGATIIDPSVEPSSAMNPRSCVTCRRRKVRCDKHMPCGNCRKAHISCIFPAPGRAPRRPRPKDPNAPPKQTSEREVELMKRLRKLEGIVEELSGQIEVDTRQPTSSGNSPEDSSHPVGDERRLESTETSPSTALSGRTTRPADSGRSIATAGITARQAALNSPMQSPGSSHVHRDFGRLVLNDDGKRRYVSNAFWSRMSDELSALRAETEKFTDEESDESDDDGSTPATSTSTKDQQADHHAFIFGYRSSDVDLRKLHPLPSQIPFIWQIYTENVDPIVKILHVPTMNNVVRQVRADMSNLTPGLEALMFAIYYASITSMEENEVQLNFNTDKARLLDQYRFGTEQALAKANFVNTSDAMVVQAITLYLVVVRRNDSTRFSWTLTGLVIRIAQSLGMHRDGTQFADLTPYEIEMRRRLWWTLVVVDLRSAEDQGTELVIAERTWDTEFPLNVNDNDFGPDMKEFPTERQGATDVTFCLIRYEICSLARKLHSSVNALAPCPKDTSITFEEREEMLLEMYNRVEAKYLKPCDDAKGELLHWVAAAIARLIMAKMSLTVYQSVLFPGVGLEVSQHARDRIFNSSVEVVEYSRLLNNEEKCKQYRWLFQTYTNWNNAVMFPIRKLFVKAQKHRESEIERLRNDPAAAEKLDMAEDNMTAPMITFQHLPKSVRTSIALDRWRTLVGRPKPDKTSHRSCMDVVPATTPPNSVKTVTPPSSAYQKQPETDFTPTQFSYLDAAMSQVVFNSESLWGAAYDVAGHMGGSNGLSNEVQSPMTQPPRTMSGYASNGSSGLNSGSGVFSGNPFNAPVPSSQQPLPQQRQSTTATQSDSAKTTPQLDNNPRRGCGQTMAGIGVRVRADRRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V528</accession>
    <name>A0ABR1V528_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663055.1">
        <property type="nucleotide sequence ID" value="XM_066817363.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050423"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="120" mass="11441" checksum="87DE4C2EA2AC932A" modified="2025-10-08" version="1">MSALDVHLDATGTPLAVGIMVGAACGSLLVLEEPGPLHAVGNSVRPAGAMVVGERDVGGVEHRARHNGPRAPDRRRGAGGRGGGVGEGGDSGVVAAGAAAVDPARGGGDGVGVLATGYGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5A2</accession>
    <name>A0ABR1V5A2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Ubiquitin-related modifier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">URM1</name>
        <name evidence="7" type="ORF">PG997_013103</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the URM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663109.1">
        <property type="nucleotide sequence ID" value="XM_066817417.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050477"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01764">
        <property type="entry name" value="Ubl_Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03048">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015221">
        <property type="entry name" value="Urm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14986">
        <property type="entry name" value="RURM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09138">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037379">
        <property type="entry name" value="Ubiquitin-related_modifier_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="modified residue" description="1-thioglycine" evidence="5">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)" evidence="5">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="115" mass="12711" checksum="F6758F3453441DD3" modified="2025-10-08" version="1">MAVETEAGSQEVAKMPVVVEFSGGLEMLFSDQRRHSLSIPVATSEGKPATVAFLIDYLCRNTMKDTRKELFVLDDHLRPGILVLINDADWELEGEEAYEIQSGDNILFVSTLHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5Y7</accession>
    <name>A0ABR1V5Y7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662459.1">
        <property type="nucleotide sequence ID" value="XM_066816767.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049827"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="89" mass="10789" checksum="792889C294614FCD" modified="2025-10-08" version="1">MIPSLSPLSLALLEYYVPYYYYYYYYYYYYYYYYYFHNSDDDWDDIQPMNQGNGTTGGSWREMLAGSDSTPPRSRHFGPGTYPPDPYPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6E2</accession>
    <name>A0ABR1V6E2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013234</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663240.1">
        <property type="nucleotide sequence ID" value="XM_066817548.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050608"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051439">
        <property type="entry name" value="XlnR/Xlr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663:SF1">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="219"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="824" mass="90310" checksum="EACAE54F2A6D51D5" modified="2025-10-08" version="1">MASEPYPLVSESEELPPPPSSAAIDTALADGLPGQSDPSSYDQHHHHDQQQQQAELEQQQQQQHQHTHQTDQSLLDQPSLQHDHTHQEYDNQLPSPSVPATTEQESDHIPLSYDGLPSPISAATAAHQGVQLLQAATAESAEPLSPSLIAQQYAQSASLHVNDAAAAAAAAAQYNTGPVSVSPSAHSHSGAGGPLTNGHSQGAQSSTPPAQKVTRLRRACDMCSQRKVKCDESGPPCKPCHDLNVECTFQREMKRRGPPNKHAEAAKAAKRARIEEAPIDSPGPQHAAEALVSIAGHEGGNGIMDAETIAPWPVLSLLVDDFFTYIHPLVPFPHEPTFRQAFHARADRTDPGFLALLASMIGSLVASFPRSARAHLKASHSPSLFPTAISMIDRCRSVALEARGPLFMAKEDMSVNDAATSYFLGLAAAYTFQYKACRRFMAETMTFCRELGTHRPPDTSMLMSSGTDLASSLHAASKAINYITDQIGKRIFWVMVAGVRSMQQMGASINEIPIPPPNAQQPYPEMPLEVDDEYIFADHVVPQPEGTMSLVTGFNRNINTYLSMNELIGIDMCYGIKFFEWSAQRTMLNNALNQAKAITETLPPELQVDTANPQAERNVAFLDESGFQYCPPAFPAIQPAHDVRHAFAEQPSRRRKLQLEIQKANIYASQLATRSYYVERYLNLRDTHRAQSNMSENGEGGGKDEVDLMITNERELIVQHLLTVLTTITQRNMEPNGASLVNKIRQIASTLLNDAPERKGPMAMKAEEYLSKFLDIMMKLEKTGTVTGGANGTMTPHDEEEELQHWASLRDYQIQFAANGGFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V770</accession>
    <name>A0ABR1V770_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013767</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663773.1">
        <property type="nucleotide sequence ID" value="XM_066818081.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051141"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8067020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="94" mass="9957" checksum="5CC92722E52479D9" modified="2025-10-08" version="1">MEKLEPATLDGPLFIGQAKQVKRCLAVKQRVNVEAFEESQDLRKDSRDEGGPSAAEVTTRLLAEDAKPSKSSRSVNAGGAIAAQIVGIPLPTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V784</accession>
    <name>A0ABR1V784_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663800.1">
        <property type="nucleotide sequence ID" value="XM_066818108.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051168"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="296" mass="32569" checksum="CD23D44B43BF870B" modified="2025-10-08" version="1">MGSSYEAPRHVPNEQHGNPDVTRRGILKDPSFFATPLTSAAGDCGHTVAGEGDPAANQAAPADDSSSSPRRHRQVVKFQTPPAGTPQTILPNTPNTNWSTWVSPSYSSPSYQDPNNKNSHSSYTISQPQIHSNSNNTSRGDGSGSRNSSQQPYQPALIMKMKKYPFGFNPQTPPQQMAGYHPTPSPPLSTPPQQQYQSPYYPSQQQQQQQMPQPPMGMPGLYPPGPPQHYQPQPQMMPAPPQYPSSMPMPPQNMANPMQAWYNTIPEPPGRPLRASHSSHAWHPVLAWPQFYASCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7B2</accession>
    <name>A0ABR1V7B2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">5'-AMP-activated protein kinase subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013829</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase gamma subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663835.1">
        <property type="nucleotide sequence ID" value="XM_066818143.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051203"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04618">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04641">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF35">
        <property type="entry name" value="LD22662P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="91"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="172"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="250"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="322"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="385" mass="43707" checksum="2AA36EB49603004C" modified="2025-10-08" version="1">MDEVTATKAAADGREHDPAMPSQSLRRPSAGHEFQLPFRVVQPSSYLRPKSQKTVSFEPTPMSPIDEEQLQGLQGVRDFLRIRTSYDVLPLSFRLIVLDNDLLIRKSLNILIQNNIVSAPLWDSHNGRFAGLLTSTDFINVIQYYNQFPEQIDNVEKFRLSSLRDIEKAINVQTLETVSVHPGRPLYEACSRMLRSRARRIPLVDVDDETGRETVVSVITQYRILKFIAVNTEQHTSLMKKTIREINLGTYTDLATCKMTDSVLDVINSMVVRNISAVPVIDKNNVVLNVFEAVDVIPCIKGGAYEELKSTVGEALAQRPEDFPGIYTCQEDDRLDSIFQTVRQSRVHRLVVIDDDWHLKGILSLSDILKYVLFHGEEGDYFPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V816</accession>
    <name>A0ABR1V816_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664086.1">
        <property type="nucleotide sequence ID" value="XM_066818394.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051454"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="339" mass="35703" checksum="61483A60467A8FCD" modified="2025-10-08" version="1">MSAMTTATITRNDFTIEPFPAYAYASEPTSSTATPSDTDHRQRWSSPSEVSSLHSFPSSRPEHDRPVSPPAATSGPHPPALGHVAERPVAIPQQRPTPTAPFYPAYAPSLRNHGITPAAWRKFVANMNEAILTTSSVSDHTRSITRRIRAASGGMWSAIVSSSASLVPGSKDNSNKNTDNAANNDESGAANGTGASSTGRTSPPTPTSPTTSGPCRTLREERVIACIAAANIAWFHPQGLHVAMVDTTVLAGRLVGAGSGDVRGILPSRLVEAARPRRDEGPAAQLAALRPWIAELEVDRPESGGSGSAYAAKPLLDLAPYSLWIVVTRRTEGDIAAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V881</accession>
    <name>A0ABR1V881_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663027.1">
        <property type="nucleotide sequence ID" value="XM_066817335.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050395"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="624" mass="69010" checksum="02D342EF004E50CE" modified="2025-10-08" version="1">MSKNTVRERPVPTMSKPDGTITDSLAQGPCAKGTPIPCDSTQDTVLSIKEVKEPRPAGIDGPSRPTTPKPASTWPKASNDDTEKEVQQTQLAKDKVLITAQKMSLAQSQHGTKPWEAKEVSPTTIAPGHEENQKAYQREIKAMTRSLKVREIQRMLSPNPNNEVKFTEYWEQKLLPQIVDILEANIQGTYSINVRRGYGPDQRVIDLMTQGNCAKKYSDVLEAAKNELLPEEFSSTTQFDFRSGKHVYCVDDADSQISSQVDYSAHCLVGNPHHYNVPVMGDSAGSRSNDGSATLGPLLQIGEKFYRLVNWHMFDDGREGRFRRWNMKSPPEELDLVHPSPSDLQIYSPDKQHVEMGNLVAFSGHMYKTYRPATSSDAVTNPLSRSSQVTTDWALFETKGPGLLNRIRHIMDGQRSDPAEPAITGTASEVKIGDVVCSTGRSSGHSFGTVCRRGLLKNEDGTFLRDWAVSSDYDDSWHDGMGAKGDSGAGIVNCVTNKLIGQLWGRNHYDEDPKEPAITYFTTMSEIYNDIQVRWPDGQCPRPRLPGEVPSTEEARGTSVTNIGGIDEMLAAEDHTPPSGEGYSNLESKSRRSSVRSSILVASCGNIMAARWVQHAATWPRLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGW2</accession>
    <name>A0ABR1VGW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664248.1">
        <property type="nucleotide sequence ID" value="XM_066814958.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048018"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF77">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="264" mass="29521" checksum="2D48905B021C444D" modified="2025-10-08" version="1">MSENPRLAPDYSRSVVELYKDVAQVMMEASGTLEVLSHHNRPARGIEGLPTWCPDWTILRGKRILLWPNQYQADGHLHDPAFFRIRDDTLILQGKVLDRVKWLKVFQSDNFDSQERIYRDILDIELVARQMYNQSHGTDSFDDAFRRTLVAARIHMKGPNQDATVLGANAADSLWAAWSSQVEGRPCDMELAKRYNSALYSAMSGRAFVITEGGAIGLVDGTVRIGDVIGVFSGGRVPLALRQKQETSPTAASAPSLYELVGEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH64</accession>
    <name>A0ABR1VH64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664290.1">
        <property type="nucleotide sequence ID" value="XM_066815000.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048060"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="39739" checksum="E09771D258E22E77" modified="2025-10-08" version="1">MGKYAFSLVDNVFEDIFRTDPNNRKPPTLIRRPQLGLIPDFDRASSSCDKSILQPWARIRSYVDELNMKNKQGAKYKVIFVLRHGYSLHNYIEKGVKRVNEAGEEVKNDWRKGLKFAYQKEVSLEALRGAGCEIPRVLEDHLHGGDPNAAARVSLYDAALLPKEITLQIRGSGVTNNDAEDLGKQWVSWVETDKFPLPDAIYTSPLSRCLETTKKVYGPVFEAHGGAHEFRPIIMENLREKGNGDACNYRSTTKHILDQYPNYTPEPDFAQKDEYEYQIQQTKDGEPTESNKEIEDRMRKVLNAIFDNDETSVVSLTTHSFSIGTLTKVLGNARILDEGDITAFLVKAVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHE7</accession>
    <name>A0ABR1VHE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_010847</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664452.1">
        <property type="nucleotide sequence ID" value="XM_066815162.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048222"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF1">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE CELB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045830495" description="Glucanase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8070644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="457" mass="48820" checksum="702E160085100FF2" modified="2025-10-08" version="1">MAYMLASLLLASVGVTEAQRIGTAIPEVHPKLLTQKCTTSGGCVTQGTSVVTDALSHPFHVVGDMSKSCNPNPRGSDEFLMDRTICPDAETCAKACEYEGVDYKSLGVSTEGSALTMRLFLPNEMGGYTRVSPRLYLLAEDDMNYEPIRLLNQEISFDVDMSTLGCGLNGALYLDEMDFSGSRSETNPAGAQYGTGYCDAQCYNKTMINGVVSTLALHFLFLTLLEKPTDEQLTPPKPNLNNSGACCHEMDIWEANSIATALTPHTCSKPGPFLCTGAECGRDASGVCDKSGCGLNPYKTVGPDFYGPGKTVDTKRPFTVVTQFWTDPKTKKLSDIRRIYVQDGRSISAASPEGEAAGGGANNTVTAEFCTSNKKEAFDRLGGMEAAGEALDRGMVLIFSIWNDLKTNMNWLDSGEAGPCGPDDGAPDKVLAANPNVAVTFSNIRWGDIGSTTPKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI13</accession>
    <name>A0ABR1VI13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664330.1">
        <property type="nucleotide sequence ID" value="XM_066815040.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048100"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="285" mass="30638" checksum="28F6EDB91CAD9A04" modified="2025-10-08" version="1">MLTTAQQEKKKSRSDSEPRPNNSSSTFADRQSLSSHHSKPESSTDAYEKMKAECPRFAALDAAILAGFERADAEKKSECAGDVDGEKEEDVDEVSNYEDAQEYIHDFDYDSDAESLEDLLAAFPAAPNDKDAASSSASDESLSTKSSKSKSSSTIASRRGKTSLRIKVSPYDALSNDSSSSSSLCEPSPYRPPTTTSACSGNSKPTALETTFDKVQDMYNKTLVVEQAIARWDRMYADSLGLEDIVGGELSAQLESSDDDDEDEGQDGGGLSTAGAAVMPHPGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIB4</accession>
    <name>A0ABR1VIB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664767.1">
        <property type="nucleotide sequence ID" value="XM_066815477.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048537"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="87" mass="9695" checksum="F1CAABDD1A530DFB" modified="2025-10-08" version="1">MLSSSSSGSEDTDNGSSFFSTYKYKLLAGTYLIITALLCYRVHRQPYAPAIKWEQYETIFKGTSLSAVVGGVAMSNGGQRRYTMYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIN7</accession>
    <name>A0ABR1VIN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Spc98 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011304</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664909.1">
        <property type="nucleotide sequence ID" value="XM_066815619.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048679"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF14">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="260"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="563"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="134"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="836"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="910"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8071101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="941" mass="106127" checksum="7660AEB5BA052A61" modified="2025-10-08" version="1">MASVSSSDKDRRINVSINRLIAQHISPSANLTNEDIQARQKFYAEEIKAAFDQKPSSALAPDINHASDLIKRKLVQTNPGQALRFSNLYSRLLALPVLNQKWGILYLLNQLADSPDPQEDDPEAYEEYIAEERAERRQKLERGDRHATPEVSKLGPNAIHPNVEDDFQPSALRNVVPAPRQPPPREEQTADETDPESMADSSGAAASSFGDMKRQMLREQQLQRDQREQQSRPQTRDVFIKSQLLSDNYTAIDPSEPTLLRDLPYTLQGLSSATLPFGKNYTLNLPRSLPTPLVSILNTLAEPSLLYRTLEDFVKTPDKGLLNQSLRAAISNELRAYLTLVATLEGQIRTALASIDDNAPRTGIGKAGVTLKRCVVWTREATMGLRLMSVIAEESKRKRGGQLISLIHAFSSSHGDPIVGAFAERLLTPVTRPFYDILRHWVYDGELSDPYREFFVHENTEEEMPKNKAGSSNVWNDKYRVVKEMIPSIITEEFAMKIFLIGKSLNFIHHSCGDAAWVESYSKESSKELRYGDTATLETWIDDAYKTTMRRLLHLMTSKFHVFEHIGALKSYILLGQGDFIALLMESLAANLDRPAGAQYRHTLTAQLEHAIRGSNAQYDNPEVLRRLDARMLQLSHGDIGWDCFTLEYKIDAPCDVIVSDWGNRQYLKVFNFLWRIKRVEFALGAVWRKVTTGSRGVLITKHTAVQQTWKTTQGVLAEMVHFVGQLQYYILFEVIEASWTELQAKLRQEDITLDDMIEAHTKYLNSITHKGLLGARRRRFAGSESAEDENSYMIQLGELLRTMLSYRECVDGLYSWSVSDFMQRQENDLITTSNVTQRRRGGGGSQEEEIPGGLTSEFPVLQERLKHLGDRFRSKLQLLLGDLAYQSDVDLRFLGVSMNFNDVYQPVRRKAKGTPAAAPSAAAEKDRGGNGGGVEKSAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIN8</accession>
    <name>A0ABR1VIN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ureidoglycolate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011281</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-ureidoglycolate = urea + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:11304"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="4.3.2.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664886.1">
        <property type="nucleotide sequence ID" value="XM_066815596.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048656"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.480">
        <property type="entry name" value="Ureidoglycolate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007247">
        <property type="entry name" value="Ureidogly_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024060">
        <property type="entry name" value="Ureidoglycolate_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04115">
        <property type="entry name" value="Ureidogly_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="93" mass="9726" checksum="4A8677940EBC4E6E" modified="2025-10-08" version="1">MLVQTLPLTTSATLTAQPLTRADFGPFGEVLSNPRPDVQPSETEPYTVTSTLPFAAELANQGTAIKYAAIASLRNLYADGGQGPPRAAPPSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIQ5</accession>
    <name>A0ABR1VIQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664925.1">
        <property type="nucleotide sequence ID" value="XM_066815635.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048695"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="30"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="260" mass="28906" checksum="66C09A9AC3AB6BB4" modified="2025-10-08" version="1">MDDDRKGDGTSYNFELEPWKEKPHEPNAAAFRLTALPMELQLEVIDHVDLRGLVALRRTCRLFRSFVITRSYLLRRFTSIDSGNGGVTRIPAMDTRLKYCCSQCLTMPPADLLLLAKDIGYKADGEQSSSSHPLEGVESNIAAATIMDGKPSVTAAGGRALRRDGPKPSDLNGHWNVPICIMCGWPCPGCDRRPRLHPACRVWRRWLKAAWFLLGLVQFVVGCFGAIASWSVYHNDPRSLVPASDGEETFYLSVSHEGLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ05</accession>
    <name>A0ABR1VJ05_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665029.1">
        <property type="nucleotide sequence ID" value="XM_066815739.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048799"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046973777" evidence="2">
        <location>
            <begin position="27"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="229" mass="24384" checksum="38BB4C32EA5327AB" modified="2025-10-08" version="1">MLLTLPRWRFALLLLWLPRLLEGVLGQGSTGNILLDTTATPSAHTLTATAATPSTLERMLTPSRPPSPEPSSAFLPPGSSILATVYISPSPDAANGGSGDGGLRLGLGLGVGIGLPLVILLGVGCFLLWRLLGKTCPMDFLKVVATAESEKQKQQQQHRWDSDDDYYAAAAYPKELSSAETVTTGPPEILSTEVYEAGGCRGRCGLLSWAFEGCMVYGWKGVLLLIRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJF0</accession>
    <name>A0ABR1VJF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010619</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664224.1">
        <property type="nucleotide sequence ID" value="XM_066814934.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047994"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="354"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="49483" checksum="4132D6EA29991759" modified="2025-10-08" version="1">MISAVMEALMNEICSALSRKDIYFEGPQAPSFFVIYAHDNPNYGRADDRIVKKFIGYLRIIGSKAQSDRNPVIRQSPDSDSTPYHDILANQFCLLPEELTTNSVEKVLLCFSEVFHAYCSDPKGREYIKRVVKAGHDEAKRLEGRDDCMAKVQRAIRQAVNDGIEKEEGFHHVLTEIALLQLRVLLAKAKGRENDDTSTVVLVDLHSTNKIFEGLPFLSPTKHWLTLPPVNRSEASHRLFFRILERVYEPGLPLTRVLESQYNDQIQALRSKSWSSYEFRSKVLDDINRALTTEKLYTHTRYNQVESAAHANDRRAPQSGETYTPLESKCFEKLRFTGMENRQEDVIESIDLAGTCEWILAAPEFTRWRSRHEGDQTNCQLWIKGHPGTGKSVATRKVLEIVKQKRRRLEQPPQYYRISSTVEVVSHLTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJJ7</accession>
    <name>A0ABR1VJJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011631</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665236.1">
        <property type="nucleotide sequence ID" value="XM_066815946.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049006"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="91"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8071428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="128" mass="14878" checksum="346F32411EA8BC94" modified="2025-10-08" version="1">MADSETPVTLRTRKFIRNPLLGRKQMVVDILHPGRPNISKEQLREKISGMYKAQKDQVSVFGLRTQLRPCLRLPEAMKKFEPQYRLVRVGLATKPERASRQQRKQRKNRQKTLRGTAKVKGAKAKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKF4</accession>
    <name>A0ABR1VKF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010979</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664584.1">
        <property type="nucleotide sequence ID" value="XM_066815294.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048354"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8070776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="541" mass="61391" checksum="3CBC8AC163FE0B3E" modified="2025-10-08" version="1">MSDSIPLVEFSQRNPTLQPGTDRHQQPIQHMNQNGATLVRPEDSFYEWVCRIALNLETQQHHTLQLVTARENLPGPGSNYPRHCSTLLENRDYARNSCVKSFGSFLPPLKTPWASSLRLSKASKEPIDSSGTILWGHDSTLPGNLDPSRGDYEILLTWRRQVTKFESDLIMYIWEYHKTMPEVEYAKIILRPSDLTQQPLRLIISFRSSRSNQGFTKIRGETTEKATAYHSGAATADCIEWSPLYEALVSICMVFELMITDTSEFLDICHNENRLGRQNPSTSKMRFLMHLDDCCKVAHQGVQHGLEVLDTLRKWAQESQIAPTDESRLEVLKGDLRYLDEELEKLRSSIRHEKDMLRQYFQLSSDMTGFRLTLLAGIFLPLSFTTSIFGMNIKTPTPEGLQGFSDFTNQSLSGLQPEVLKPSQALISSIAMNGPLTHGWTTFAVASLCILATLPLTLTIGWTLRKLVVLSAKYVVYWRVTLVVFGVPFVVISMFGRLFGEDFGVIILLIFWAFNGILVLYLLGTSYRAWAIKHGRVFGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKL9</accession>
    <name>A0ABR1VKL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010692</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664297.1">
        <property type="nucleotide sequence ID" value="XM_066815007.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048067"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="40"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="305"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8070489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="350" mass="38489" checksum="2C2CB9830FC85478" modified="2025-10-08" version="1">MLGGAIWGGPGKGELDDNEGYILVNVSIAFAALTSVFLGLRFWAKSFTSQIFGLDDAFLIAAWFVNLGMCAIAILMTYVGGVGRHVEHLEKTDPTKLEGWAKCLLAFEMVYFTSMALPKMAIVFLYLRVFNWRGAMRTWAYVIQTLLAATSLSFVLVACFQCRPLAYWWDRTIPGGVCIDVQLFFHAQAIPGIIMDCFIMGLPLSTIWGLQLPTAKRVALALIFAIGSFGIVSSIIRAVTFFSTAAFADRTFASVALVGWSVIETGTYIITNCLASLKPLLNYYSPAWLKRLVHSTVHSVTKYASSNGTSRAGGGGNTTTTRSTAKKQPQPREDEIELTGGMPSRRRRWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VNI8</accession>
    <name>A0ABR1VNI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665226.1">
        <property type="nucleotide sequence ID" value="XM_066815936.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048996"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="141" mass="15654" checksum="9E255F828E617595" modified="2025-10-08" version="1">MCYSPGKRFALPYYPELAVDAVRGACWPASDRGRKETGQHADKMERVHGSSCEADMPALLRFGSGYSQKMKSDKDIQGRPAKEAWHPTRLALVYRTVAHRRSVGGPSSSHWRRRGQQSIVRGALAALILGMKENRNGTRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTQ0</accession>
    <name>A0ABR1VTQ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665543.1">
        <property type="nucleotide sequence ID" value="XM_066813581.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046641"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051283">
        <property type="entry name" value="Sec_Metabolite_Acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896:SF13">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="452" mass="51369" checksum="F427829CBB5FBEE7" modified="2025-10-08" version="1">MVQPEVIELRPTGWETDPAEERFKVSTIDLLPPCTYNHYLLFWRLADDTKEQAIKVLQAGLEKTLSQARHLAGTIERDPDGGHSFTKRKDSTVKLVIMRYDREGDKWPSMDDIEEAHFAQHALGDDLGKWGIPEMTWGERPEAELANSPNTAGFQINLVRGACRQLCLYCPWHPFVAWDPANIDASRFWKCLPEEEMVEGPPMSQRHPGHPEQQAVLFHLPKSKAEEIKKLASPTDPKEHWISTYDAMCAFIWRALSRVRAPLHKPDLDSRPWYGYAVNMRPRLHNPPVPARMMHNCLVGSFSDTLPVVMQPTAGEVLSNEVPLSRLSGFIRAMTDNCTEEHLWGLVDAIAPIRDKRNISIRIDGKPPMSIFVTDHRPGDLSGVDFGFGKPLTYRHMWGHLLTAGLILIYAPVLSADPDEGCMFTVNMEKELVPVLCADPEWSRYFEYRGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU79</accession>
    <name>A0ABR1VU79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665741.1">
        <property type="nucleotide sequence ID" value="XM_066813779.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046839"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="238" mass="25119" checksum="A7B2DC8300A900FD" modified="2025-10-08" version="1">MYSFQQRRPSVADSLLEGVEAQDGRSSHEAKPRLSTPAPTQSYYYAAVTTLLVLAPSIGLVIWLARAGSAISHNYGLDSRPLGGRLTLVQAKAVDFVCSALLAPLVLVAVNWYWFSVTRVTVLNDGSTTAMPLAALVEASHTDTGSYSPVKLTSLVRSGRPKMVLLGLLVLLSAVVQTCFGNVVAYEAHSVSDGLDSPVSLRALVTGLPSFLGSGTVPPRRTGPCTCTISRRPSASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVS3</accession>
    <name>A0ABR1VVS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009960</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666237.1">
        <property type="nucleotide sequence ID" value="XM_066814275.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047335"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="895"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="713"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="713"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1218" mass="136396" checksum="061DA26052AA5480" modified="2025-10-08" version="1">MAGRALSGVDIGTSHIRAAVYRETDQGSCKVDPIPDEDGNSYLSSYLTFSGQTIARLFGERAKKTAAKNAGRTVYGAKRFIGHPVPSKELEVFAFKLINDPRGRGSPSLVRNAVAYLGPYELSALINVPSRFTQEQRRMVQDAAEVAGFGIIGLVPTTYGILATRTIEQLRQPKENWTKILAIDIGAGFLNISIASMVQGAFHMDVTESDRLGGNDFDNLLWHHLEAQAKQQGMNIYAGRGKRRARQRLLSACESAKIQLSDISQTEVFIEDFWDGQDFRAILTRQEFESICMKCFWSITDAIERALASAKLRGKHIDEDARGFLPGVPTIQYLNQQETEVNGMAYMAPLLFDDPKRNPRRMPHTLTATVVTPWSIGIGTGDGIITKVLPRYSKLPAEKSIIITWDAQKKCPQTVKSRSSQPATPASRRTPGPAPVHVFEGDEQGTMENAWLGTVDIESLLPDIIKPNFKIQVTMKLKRFHPTIHFREGVSGKTVYRELDQMGRLQRYQIANMIANEQRHHFIDVAEVDRVRVRTSLGELIDKLQHRVRNMSSPPPDGILVRIDSMRAWLDSRQLAPVESYKTRQRELAEISQAIDRVVNPRSGVPLSTNDVEFNNQPLAPKWSPNDTSRKGPLPAMYEYALNTDEVIEGSVIYGRRPEGRVCTPPMRFSLDQAIRPQAIPSTESSDSLDEEAIRARREASVEFQSIHSQVKSAQTDVSNLSRPQGASIAVTGHAESSVASSVSTPSDVSLSTQSGLTSSIQRITATMSSVSLDFNARLPKPYQIPSTPYSDMDFERISAYLRTQNHEDWSIVPRLFTVLTLIDRSDALSIFIQNGMDDMWFPFEMGTLPPSLQSSTKSRFLEIQEVVYGESKAHQLESGAKRHALFGKDDYIPFVSKKKLGRGAHGTVDKVISTISYKEYARKLFRKPKVGKNNFANFKTELDILKKVRHRHCVSLVSTYADVKYFAMILSPVGDCNLNEFYSEVRRDEEKLSMLRSFYGCLARAVQYLHDKQIRHRDIKPQNVIVRDDQVYLADFGIAHSWEGLTGSTTTADSGRTQIYAAPEVVRVEPRNESADVWALGCVFFEMATVLKGETVADLQEKHFLPRSESRCFCHNVAHLDSWAEALVDKGLPEDDLAFGWARRMLQDRPGERPDARSLCNLIAKESASCSLMFCGTCCGDGFETVTVTDQGEDQDTMWDFESHGVKTMYCFLFSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWI5</accession>
    <name>A0ABR1VWI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">C2H2 type zinc finger domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009188</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665465.1">
        <property type="nucleotide sequence ID" value="XM_066813503.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046563"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8074525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="424" mass="48243" checksum="EB96AD196B216EE5" modified="2025-10-08" version="1">MSVRGEEEQSNPADYIDRMRRVLGAEGPEEAMRQLLLDNRSRSLSLLRQAGGQFENFAEQHLRIYIEVFHEVWPFLHATTLDVVKDHLHLASSIITIGILLKKRRFRDIQTETPRGSIIEAWPMEWYQAVLINIIIGIIRNELPRSRLLGSLFIAHLRLVGMFDSTVAEAQTKIYHPGTFVPFVLSNIEQRSRLIAYLFKADAMLSLFDNQPPMLHAEELDTRLPRQEPGHRASHKLSDIVSGPFVFTTGSIVAEDVEFGLWSLVREVWEHRQRLHMMRGRTSDSTTTHNANNDNTQTNLLHRLRGWKYQLTSLQRLCSTSDASSTGEEEEANALRLIRAYRGDDDAKPNEEWQQLARSRATDRVRAAMGLHDILEACLHSSSSSSSKDSNHNITAASRDIGIRYTLLQCLDMGRQAALDQAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7B4</accession>
    <name>A0ABR1W7B4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666853.1">
        <property type="nucleotide sequence ID" value="XM_066811511.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044571"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="82"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="244" mass="26393" checksum="2646EDAA15C3735C" modified="2025-10-08" version="1">MDQPPPPTVPQLVAETVVPATTVTPVPGAAAPPPPKPAEQPPAQASNTTIEIATDDDAKDDALVATLTGIVNRVYFDTENDIFVEGTKRTDELEVRSIIQAGELAVLYLLPPPASPGHQNQQQEQQGPRKAIGCIRIRRVSDGVGELGMMAIDPAQQGGGQGSALVRFAEGHIRETLGLSVSRLELLVPSGFQHAFKARLQAWYDRLGYRMVRLGVFQDEYPKIAPLLRGPTEYRVFEKTLVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9H7</accession>
    <name>A0ABR1W9H7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667618.1">
        <property type="nucleotide sequence ID" value="XM_066812276.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045336"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="121" mass="13192" checksum="D5FF1D92797814F9" modified="2025-10-08" version="1">MTLRETTLKVPEKADKEPNKHQEYAGQNGEADILQSREILLAVADPATGRFEVDVEVLVHEGTVAMGQLEEVRHSETQLEVFPADQLLNLVLENAIMEVARGGVVLISAAPCGKFVKAATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9R6</accession>
    <name>A0ABR1W9R6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF803 domain membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008051</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667708.1">
        <property type="nucleotide sequence ID" value="XM_066812366.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045426"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF92">
        <property type="entry name" value="SPICHTHYIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="401"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="590"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="401"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="647"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="661"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="685"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="740" mass="81646" checksum="BE34DF7869298DE6" modified="2025-10-08" version="1">MDRAAQVLEVAHHIYARANETEPAGDPEKATRPPYTRSSKVGLLKANEKYEEAAGEGYGYLKNFHWWAGMILMIVGEICNFVAYAFTDAILVTPLGALSVVITTVLSAVFLKERLSMVGKVSCFLCIVGSVVIVMNAPQESSVANIQEMQHYVIAPGFLSYAGVILVGSAITAFVAGPRWGKKNMLVYISICSWVGGLSVVATQGLGAAIVAQVQGTSGSQFKHWFLYVLFVFVIGTLLTEIIFLNKALNLFNAAMVTPTYYVYFTSTTIITSAVLFQGFKGTASSIVTVVMGFLTICSGVVLLQLSKSAKDVPDTAVFKGDLDQIHTIAEQEQPETEPKADAIRGAAAIVRRFSVARQKMEEEELKRLHEEKERERLETVSEAGPEYEWDGLRRRRTTINSQMSRRTVSPNPFTPHQQREPFPAPPRTPHLPLGMIALQHRRHFTQPGTYFTLPGHPEFLDDSHSKNAQSPMRPVQLTDIAIPNAKLGGEDSSYGSRREHVYGLPDGLRHQRTEYGGAAAAALARSAASIVSASSTGQRIHFAEEDASSLAPPTPPPHRDSSQSARRQFSFQNVFRRHQADGLQELAHPHQERPPSHHHQKPPSRSGIGSRGYSNPQVKNATEEERAGLVKGDSNSIPSLPRYDDSYEEEETDEDPDAYLDDKRAERFGRGITSSSPPRPNNSDSDREIDYDAASRRKWDHSRTNSSHRTPRDSQSGSRPPPRPRTPPGGGRRNPGSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9T0</accession>
    <name>A0ABR1W9T0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional adapter 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_008083</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667740.1">
        <property type="nucleotide sequence ID" value="XM_066812398.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045458"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02335">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041983">
        <property type="entry name" value="ADA2-like_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016827">
        <property type="entry name" value="Ada2/TADA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055141">
        <property type="entry name" value="TADA2A_B-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF20">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 2-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22941">
        <property type="entry name" value="TADA2A-like_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25299">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025024">
        <property type="entry name" value="Transcriptional_adaptor_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="11">
        <location>
            <begin position="48"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="13">
        <location>
            <begin position="109"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="112"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="12">
        <location>
            <begin position="475"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="382"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="441"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="456"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR025024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8080265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="563" mass="62893" checksum="E010E08729201FCA" modified="2025-10-08" version="1">MLRPLCVGNSRFDSAGHQAGLELGGTKLHETRWVLFARRRPRGGGEGGVKYVCDACSADITSTVRIRCAHSACNEYDLCVQCFSSGSSSGSHQPATHPFKVIEQNSIPIFDSDWGADEELLLLEGCEIYGLGSWADIADHIGGYRNKDEVRDHYIKTYVESPCFPLPKRCRPSDMELAQEVSREEFQARKKRRIEERREAQKNAPAMAPKTKPTASVPSCHEIQGYMPGRLEFETEHANEAEEAVQLMQFDPGDGINPRTGELEPEMELKLTVMDIYNARLTQRVDRKKVVFEHNLLDYRENSKLEKKRTKEEKDLLNKAKPFARMMNHDDFESFCQGLVDELNLRQAIAQLQEWRNLKIGDLRSGEKYEQDKATRIQKAIPMGSMDRERLATAQRSKQNTQPEPPSGAALLIAPELPYRPATTGATPHNAMDGTNLEAKPTTNGHGAANGAPNGVITNGTGPAANTRQKFISQPISGVQPLNLSQDNAPDLHLLTPEEAELCKVSRLQPKPYLMIKEQVLKEALKGNGTLKKKQVKEICRLDSQKGGRIFDFFINSGWIGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBM1</accession>
    <name>A0ABR1WBM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Helicase-like transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_007683</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667340.1">
        <property type="nucleotide sequence ID" value="XM_066811998.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045058"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF52">
        <property type="entry name" value="SINGLE-STRANDED DNA-DEPENDENT ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="487"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="860"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="970"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="522"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="935"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1093"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="947"/>
            <end position="956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8079865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1139" mass="126958" checksum="5C7F57C88FD5DDA5" modified="2025-10-08" version="1">MPLPDCKRARSEEVLVPQELQTERALHKPSFYDDIYTHEPSLYGDTYISLHKDTSTQNGLPIPSELSSNHGAPSFDPNVLLNPRAALTTTSRTNNVSGRSTPANFPSRSSGPTPLEFQFSSPNDGYASNASTPPPFAYNGGYDISHTPSPVNGFGSMIERMNHVQDRSAAPHPKRRKVETIDLDDSADEKIPSTFGNGGGGMMGQYVKDKKEEAANSPSMSRADTVDLTEGGAKINCHSVPSPKPEHKSLQHGWWPTVKIVLNRKLGDVTNVINAKDYTRNVVGTLDPQTALGLSPLLDSARLQLRTDSRIPTRKMEGERVGDPISKAYNLDLVLYGPRRSAKAVGRHLSQKQLWLRNPTRLDSGVKYENPQSLQGIRPQPIIRDREGVLAAPVPQTVRTVEEIRNEVMGVFDSLTRSEDLPQMEPDSRIVTELLKHQKQGLHFMMTKEQPRKLSSIGKTPNSFWQLKTNVSGQQSYYNVITGQIQHQPPLETFGGILADMMGLGKTLSILSLVASTHDAAEEWSKSEPVQPRPPAPKKNQGQSRFNVPTPEPLALTRISRNSRATLLVCPLTTITNWEEQIKTHIKPGTFSYYIYHGSSRIRDPKKLAQYDLVITTYGSVSTEVNARHKGRAGSHPLEEIGWFRVVLDEAHMIREQSTLQFKAICRLQANRRWAVTGTPVQNKLDDLAALLAFIRLNPFDDKSKFTQYLVAPFKVCDPEVVPKLRVLVDSITLRRLKDKIDLPPRKDQLVKLQFSPSEEKLYKSFERNAQDKVAVLASGRDKMVGGKSYIHILQSILRLRLISAHGRDLLSEEDLALVQGMTEDSAIDLDSDDDDRPAIGETRAYEVLELMQETNVDKCFVCDKKLGTREGSTDVESDKEDNILGYLTACFHLICPSCKPTWDGETGNHGTGRCPMCSSHIRLSLTELRKDKADVEHDTHHKTGKKSSSLENYSGPHTKTRALVEDLLRTKALSEATPDEAPFKSVVFSGWTSHLDLIQLALDKNGITYTRLDGKMSRNARTAAMDSFRDDNSVHVILVSIMAGGLGLNLTAGSNVYVMEPQYNPAAEAQAVDRVHRLGQKRPVRTVRYIMANSIEEKMLELQEKKKQLASLSMDRGKAMDKAEAAKQKLRDLRSLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCM3</accession>
    <name>A0ABR1WCM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxyphosphonoenolpyruvate phosphonomutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668227.1">
        <property type="nucleotide sequence ID" value="XM_066812885.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045945"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905:SF2">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13714">
        <property type="entry name" value="PEP_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="39366" checksum="2CA954ECF156996A" modified="2025-10-08" version="1">MAPSIEYEPISRMETEAPVILQTAPEVETHHIAPPVKPISLVNAAEVVEEEGYAVQLPPACPPGRPARATKLRKMIFDTKELIVCPGVYDGLSARTAIELGFDAMYMTGAGTTASRLGQPDLAIAQLHEMRENAEMIANLDPFGPPLIADMDTGYGGPIMAARTVEQYIRAGVAGAHLEDQVLTKRCGHLSGKKVVPREEYISRIRAAHAARVRLQSDFVLIARTDALQQLGYDECIARLREARDEGADVGLLEGFETREQAQRAVRDLAPWPLLLNSVENGKSPTITVDEARAMGFRIMIFSFATLAPAYLAIKETLLRLKNHGIVGTPKNVTPVTLFEVCGLKHSMSVDMNAGGASFKGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDL0</accession>
    <name>A0ABR1WDL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008026</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667683.1">
        <property type="nucleotide sequence ID" value="XM_066812341.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045401"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF40">
        <property type="entry name" value="THIAMINE PATHWAY TRANSPORTER THI73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="485"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="100"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="556" mass="59810" checksum="1850A35FE29D1E10" modified="2025-10-08" version="1">MQTAWADFAKDPYGAGPGWERVGSGEAGGYPVAAFDVGADLDVKGWALMDNGTLDRNATLIAMADSEKTEATTTALQVMLTSQSVAVDRNQLYRKIDFRIIPLMFLCYLFQSLDKTALNYANVMGLQKSLNMQGQDFSWLATSFFLAYALAEFPQAYLLQRFPLRKVLGLNIIAWGLAMCSSALVRSYAALLVLRVVLGACESIVVPALVLVTSTWYTKRQACGRTGLWFCSIGAGQIVGGLVGFAALHGSGDNDIARGNFGGWRIMFLAIGVSNLPVAAAVLLWLPDTVDAARFLTADEKAFVHAALALDQGGNGRQVFKPRAIVEALADPAVWLLVSIIVLTVIPSGVIITFSATLIKGFGYTPKESALLNMPSGLVSIISTLLSTFVILRGIPRWLAILMLLVPTMIGAGLMSFYKGQGGSLAGIYLINFTIAPTALVFNLVGSNTSGYTKKVTSYAAIAIAFSIANIIGPQTFQAREVPGYISAKITIFATNGAAIFATILLRIIYGRRNRQTEKAREAQLAAVARGETAVEALIDDEDLTDRKNPAFRYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFU3</accession>
    <name>A0ABR1WFU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetyl-CoA synthetase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008852</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668509.1">
        <property type="nucleotide sequence ID" value="XM_066813167.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046227"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="40"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8081034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="592" mass="65753" checksum="56D11FD13E051B05" modified="2025-10-08" version="1">MANGPTPTVPGEVGRRLLPVIIDEVAREDPDRAWASLPVDDYDLEQGFEDVSYAAFANGINKLAHCITKALGPPPDDSKFDAIVYLGVPDIRYYMLIPAAAKTGRQVLFSSHMNSLELHLSLIEQCDCRAMLLSRGVYAADILEKLPMPTVEIPELDDLLDLSVKAEPFPYTKSYDEAELDPFVICQTSGTTGAPRPITYRHSTMSTLDMQSELPDVDGRKHMVWQRGVGTRFLMVASPFHAIACILAMTVYAFGGCTLVPGFRNRPVEGINEMCDIIKYSKAKVGFMPSFLMELIARRDDAEDYIKQMDTVVYGNGILSDFAGQMWSKTTRIFDVWGSAEVCTPPQLESDPEDYQYCCFDIEAGGCVFKERDDLEYFGDDGARLELYELVVTLTPKSEKYIGYWACQGEGTKAPAGPPYPEYSTQEVWTPHPDPEKAAYTWRFVSRVQDLVADAGEFALAFERTLSKHGMVQHAVVVGQGGEKPCVLVELADGYTKEAARRCLCKDVIAPANEDVPEGARIDESHIVFVEAGEFVRSSEGHMLRTQTQQKFQGRIDAVYGRAPSEISVSMRPRYQSIIETVEVSHVVEDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLN8</accession>
    <name>A0ABR1WLN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005673</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668911.1">
        <property type="nucleotide sequence ID" value="XM_066809988.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043048"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF115">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="160" mass="17650" checksum="BFCE2F85068EBC07" modified="2025-10-08" version="1">MNMYLNADVTDVCILHERWHATDARSFAGSLLLCALLVALYERFAAWRRRYAARVARQAKAAARKKELSSSSSSDKKGPACCTAESPTDRSRRRRAAAINAALYGVGYLWGMTNMLIFMTFNVWVMLACGVGAAVGKFLSDDDDQAEEVSGEEEKEASCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLZ8</accession>
    <name>A0ABR1WLZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669051.1">
        <property type="nucleotide sequence ID" value="XM_066810128.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043188"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="239" mass="26688" checksum="BEE16E7960540D22" modified="2025-10-08" version="1">MSDEHLDQSDSEVSDIVINASAMTHHDYWARAAESTPTLLSHSSRRLRGRPVSYHPSGYRTNELSPRPRPLSHRETYWDSVGSLDAPLNRISSHREHSSRTSHSRRTSILRDVYQMQEEARLPEGYTPPSSSSGTEKPNRHSAASVDLIEAANQIKNAGYVGQMRRISGSGETEDDTSSAPDAIQVGGHTYVRHGSGIDRENARRRRPLRKRRKGSPEGPDMGIGHEILFFLLIATGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM96</accession>
    <name>A0ABR1WM96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669169.1">
        <property type="nucleotide sequence ID" value="XM_066810246.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043306"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051604">
        <property type="entry name" value="Ergot_Alk_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162:SF1">
        <property type="entry name" value="PRESTALK A DIFFERENTIATION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="12"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="326" mass="35872" checksum="8F3A7AAF3F1E6D92" modified="2025-10-08" version="1">MAPSRVILVTAASGNIGEHLIPLLASDPTTKLVLPTSRASSLQAQLAQHQQCQAGSNVFIEEGSIKDPAWLQGLLASHKVDTVFLNLTGDDELFTSLNCLDAVSRSGTVTQLIYLSGCMDFDTSENIQRWIAICSAAHVLVKPLVEQKLVHGENLPFDWTILRPALFFTNDLRSKQSMLETGVLGVPFGEAGLSRVAPWDIALAVKNLMTAHNNNGDSTNKWNRQKVAIGSRKAFKGSEIARTWSEALKKEINVLPANEEGFQKLEDWFGTLAGPAWGRDLRLMHETFAAHGFGMTEEQYQKQVELLGQEPADYVEWVNSTGAQWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMI7</accession>
    <name>A0ABR1WMI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_006021</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669259.1">
        <property type="nucleotide sequence ID" value="XM_066810336.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043396"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF45">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="15"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8084750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="515" mass="56412" checksum="990DF46FD93E54E4" modified="2025-10-08" version="1">MPFGLTGRALARMQTALIVAPAFILFGYNQAGLGGLLTEDDWVKTFPEIDTVHAKGAEKSQKSTIQGLVVAVFVIGALFGSLSCSWSGNAFGRRNVIFFAAICTLIGEILEASSFSLAQFIVGRIIIGAGVGQLSSIVPVWLSETSGAKNRGQTVVVSGLFICLGYVLESWIDLGFFEFKEGPVTWRPPIAIAIFFSLVLMASIYMFPESPRWLVMKGRVEEARPLVAMLRGHAVDSLEVSSEIAGIEYSLEETSNTAVKLTDMLKMGEDKLAYRFGLCILLQFYQQMSGSNLISVYATILFQNNLHLGSELARVLSGGALTWKFLASFIAFFTIDRFGRRALFIISGAGMACCMVSLAITTSFPEDNRGAMIAAGCFIYLYNTFVPIGFLGANFLYCTEVAPLRLRMAMSSISTANHWLWNFVVAMVTPVAVNTIGWQYYIVFAVISACIPVTVYFLFPETMGRNLEEIDMMFKEAPSVWAAVKFAKTRPIAMPQEYSSSKDEKADHVESGSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMS3</accession>
    <name>A0ABR1WMS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">GPI inositol-deacylase</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_006048</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669286.1">
        <property type="nucleotide sequence ID" value="XM_066810363.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043423"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GPI inositol-deacylase PGAP1-like alpha/beta" evidence="5">
        <location>
            <begin position="148"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="344" mass="38080" checksum="28B3D5DDB720560A" modified="2025-10-08" version="1">MTQSASRCLSACSVNHICRPLRIAATTTRSLRPSAGQWCPTPAPHRGYSTSDDGDPRMKELGRRIQDDYANIRENYATPKHPIVLAHGLLGFAELKVAGPWLPAVQYWRGISEALKANGIEVFASAVPPSGSIERRAEKLAQGIAEVTKGKSVNIIAHSMGGLDARYMISNLQPKGVDVKSLVTIASPHHGSAFADYLFDEIGQERLPSVYKLVEGAGFETGAFSQLTQKYMRDKFNPKTPDDPSVRYFSYGAMVERLPFLSPFRLSHDILDRLEGPNDGLVSVTSSQWGQYEGTLVGVSHLDLINWTNRLRWMMRKLWAGRDPNFNAIAFYLDIADMLAKEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMT8</accession>
    <name>A0ABR1WMT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669358.1">
        <property type="nucleotide sequence ID" value="XM_066810435.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043495"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="577" mass="63863" checksum="7B12BB8B42BCD40A" modified="2025-10-08" version="1">MAFHQPTHQPIPRPYRSVDEDDTQPASQAIPQAVEESQTWVLFSPETDAGTTTSYLTTTHQTKSTPGRSQLSDLGSIHSVVRSQNSIDQHHSASLIDDLDADEDEDEDAELDSLDSHLPEFRTVPNFANHHADGVAQSTPVLPAHDGLGSFRLDHEGIGQDMQDRLYAFEQYNPRRIKRRRESQELAQAELMGEECDIDKMQRIESWRLEHSRFLLEEIQKETRRRRSAVSALHVQEAGRSLEEPVVPEANAIDDVDHSEAWHDEHASVFASEPEGAWSRITRKVIRDLLGIDDRVLSVLFGDALPDEDDLSSTPKMSRILRDDTGDISSSNLAESTWQLRLLERIARELGSFVHQLSEHPGAFSTFSRIQQMPIPYAGLPPIPETANDASQASIARDASAVLPEFKPTLAHQSQPISIPQAQAAATASQETSQIQGDNTASTTFTKEEWEQDLDIRLVFRYLRSRFLSRPSSGGVSGSSHLATSSTVDAAAKAARVRQHHPLVSRSRPTERRAFRASTPTSPVHYRHASSCASQSTRRSVRKSSCSSRHYWDVGAGSVGTGSLIAAAGPMGSWGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMX9</accession>
    <name>A0ABR1WMX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Erythromycin biosynthesis protein CIII-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669297.1">
        <property type="nucleotide sequence ID" value="XM_066810374.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043434"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="2">
        <location>
            <begin position="302"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="429" mass="45863" checksum="4BD8F9D40BF89104" modified="2025-10-08" version="1">MSTQSDNAMSTGDKPRWKFLLHTFYATGHVLPMQAVAQALVQRGHEVVWLASPDQQARVEASGARFEATDEVAKADTFLKTTEPTTLEGCVEVLFGGGRLVAQVADLRRVLQSYSPDCLLNDALPQGAAALYELGEVPFFATLGVVPLYLPGAGEHAPTSALGTLMSQHKWTLPVINPQREVLGLMPLTELDVVQYSAQLHIQASCPSLEYHQPMPQTHYVGPLVSQQTQAPDLPEWWDDVLAAASSGRCIIGITQGTFAMDPTSLLIPAIEALQDDPSLLLVVPSPHETAIRAQLGSSLQAQATTNVRIAPWVPYDQLLPLCSALVTNGGYGSVTQALAAGVPLVCAGTSEDKKDTAARVRHVGAGVDLGTERPGVESMRAAVRAVLEDATYKANAVRMRDELRAQGGAGKACHLLEEAIARARVERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNR3</accession>
    <name>A0ABR1WNR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006378</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669616.1">
        <property type="nucleotide sequence ID" value="XM_066810693.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043753"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047521914" description="Carboxylesterase type B domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="2">
        <location>
            <begin position="40"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="634" mass="68355" checksum="0940B51F82ADA8A7" modified="2025-10-08" version="1">MGRILRYAAALWALASSISAAPKDPIVTVDSLGVQYRGLTRESVEEFNSIKFAEDTSGSRRFAPPEPYVPPRDGGVVDATAPAPACPQIRDPLPPFFGDTPDQSEDCLYLRITRPAGTKPDDKLPVVVHVMGGGVIKGHSQEALYDPTHLVTSSSRIGQPVIHVVLNYRVTIFGFARLPILKDQQSLNVGMRDQRAGFQWVKDHIAAFGGDRDRVTAFGLSAGGTFTSVQLMAYGGTHGVPFDRAWCMSGPPGTALNTTSDATELHTRAVARTLGCDPTSDDSEILQCLRDVPMDKLTETAMAYAMQNHPPAGLFTFIPSVDDDFLPDRPSALYKTGRFVKVPIALGWTHDDGATNAGPATDFQTEADIQTAIRHFAHALTDDDYAALFALYPASDFAVEVHSYEARKAAADPAVEVHYFRAARILRDLLFTCSSLDFASEMSKPSDRPSSSPGARLYDLNQSTVTPLLRAAAGMPWLGVVHGSDIDYLYNNMFPRETLADADLALSDQLLAAFVNFAYTADPNGAGAAVPSWPEAFPSVTNGGGSSQSRPAVDVQLIGGPWGTGNCHLAADTGVAGEGSFAAEQMDMQHPMVDSTKYGEMGGERLQQGQRELERDRLLERCGFINTLAEKLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNW7</accession>
    <name>A0ABR1WNW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-binding protein RAP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_006389</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Chromosome</location>
            <location evidence="8">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RAP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669627.1">
        <property type="nucleotide sequence ID" value="XM_066810704.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043764"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11655">
        <property type="entry name" value="rap1_myb-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021661">
        <property type="entry name" value="Rap1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038104">
        <property type="entry name" value="Rap1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039595">
        <property type="entry name" value="TE2IP/Rap1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015010">
        <property type="entry name" value="TERF2IP_Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16466">
        <property type="entry name" value="TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16466:SF6">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08914">
        <property type="entry name" value="Myb_Rap1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11626">
        <property type="entry name" value="Rap1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="2 8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0779">Telomere</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="ARID" evidence="11">
        <location>
            <begin position="383"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="138"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="247"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="503"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="474"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="540"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="569"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="603"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="641"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="695"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="764"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8085118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="932" mass="106175" checksum="9FC1522C2C686E44" modified="2025-10-08" version="1">MRRTWINHIKNNGGQIVALEKNADYMIADHVRKDSPQGSYSWKWIEDSVKKGKLLDADDYLIGGKPEEQPRAGPSAPGKSTRTPFTEEDDRILMQWVLRRERQGESILGNKIYQELAIKNPRHTFQSWRDRWVKKVSMKPRPDVPGEEPEAQDAVEPEPTASLQRTSASSRPQPTPSPVKQERKSRVKFTAEEDRELTQYVLERTANTGHDRGNKVFQEYADEHPEHTYQAYRDRWIKYLRPSFEDDKNENEEEEVPQARISRSKTNAIQSTRNERPEPSLQRPKVNSKPVEGVPNITLEKPESSRRGNSHNLTQHQDVPAPDSPGHIGRSPRNLKKMETQVEVDQQLNEENEEERHQDVHTPVATNNGKASPAKANYTGTLLQSKEEFYPVYQDFVQRFTHIRPNFWPTVRNQSFDLWDLWQSAVSQKLDRAERDWQQIAENLGYNWIEHEGVEDDIREIYENHLAEFEESLAEWENDESDDSETDEDVPDETTAVIGVSDAFDRNSEEQFNSSPPKQPSLKRTHEAALLSDLRYPDSSGKRQRFDRDSEIPSTPDTKNGTAHLRRPSLSSRARQNAQKGQGVPDNGDRTVADGATVHPKMRMVEPETQDFRYDPETQAFRYDPETQNIDFDTEMDDVQGESQVTVTASQQLHHESEPGSSPIKPPNRELARPSTPTPKRKAGKPPFVDSPDDEHDKPTPKERFGKGKNPILADLEKEQHQKQLRRISAGSPQKKPIVAPQPKPQRQSVSRPAESRPPPPSFPSSSKPSSKPAKLPPSSSRNPKALPPATPAGTAPKPPASSAKDDPVASQLARLNRRIDYLVSLGYPPSVARRAQEATSWQKALVNIIIEGLKKGEPLPTNIEGVWTAKDDMKLQSLLEYEAAGDTSDEKQARKMGKFKDHLMTKHGEAHMELRKIWYEDKKRLGWEEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPC6</accession>
    <name>A0ABR1WPC6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668844.1">
        <property type="nucleotide sequence ID" value="XM_066809921.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042981"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="339" mass="36889" checksum="BAC8A73B08215292" modified="2025-10-08" version="1">MADMTVHPTTTHDQPCQSVVAPAATPTQPTELAAANAPLIPRQPSSDGAANGSSSRDEGCHLLAKLPLELRNAIYALLLPATPPQYPSSFRRYRMPASARPRFWTPAIAQTCRQVRHEVLTLYLGDNLLRVGLWVQEPWDVLYLERWLQDLGDDARLVRRFAITHQTVWADTTFTVVPDAFGVESETLVGIECDFGAPANPVSDQIPAGTVCGCPLTARLPPRAAVSVPPRTADCALTRAVYAFLALLDEEGQDAFAVPRFASAEAWGAAEGSEGALSALRAAAVGPKTAAYRRRLGLGFDGAVVSEIDFNGWRWTVYHQKWAHKKLGPAEEEHPCNQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQH8</accession>
    <name>A0ABR1WQH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670303.1">
        <property type="nucleotide sequence ID" value="XM_066811380.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044440"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="148" mass="16784" checksum="C70164BBC99C083E" modified="2025-10-08" version="1">MVHDAPISLLNRPELGMIVEKSSLAYVVCLSQPAGLSIDRPHKTDAHHQLVFRWGHAGRARAKTQRPMEPPPTVRPPLRSEAKRNAEFPGTERRNIVLRRARLSRSSHCRGWPGSPTTKCLLPDLFIPGTRTRIVTPFVWVFRRPSPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQJ5</accession>
    <name>A0ABR1WQJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670320.1">
        <property type="nucleotide sequence ID" value="XM_066811397.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044457"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="453" mass="48015" checksum="959EE44F429335CE" modified="2025-10-08" version="1">MAVHYLRIKNRSGHAQTFQCHGYNGNKDLTIAANSQANIEAKDGTSGAIIAVHDGVIGEQCEITKAGWNGNDTIDISNIVGAGGNMTCQQVGDPPGKFKGHETFMQACNKAWHALSQQKRDQLKGHVTLDGKGNVKRIGAPKEFQPLEQFVRTFANGRTYIGVGSWAGGKGNPEDDKQSSAGKGSKDILIVYSDNNAAPDPSKPFTGQTLQAQGFAAASVGEDNNDAQAPLIQSRAVEAPKEETEAAPAAEEEQTFSAAAAALGPGIQLTNKSAKKHRYYFYDNYWNGNGEAGANFDHPLKDVEVGPNATVFVPLKLEFKGRVQRGNEIPATWGEFQVKAANDGKAHGDISLQQGCDGAATVASTDGTNVSNGFTQDIVKGAPAAALDKKPKSGEKVLASTEGNWIHPGGNQAAVDYEYKVLGHGKAYIKGGTGVPDIASKNNCLHFTFYVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQK0</accession>
    <name>A0ABR1WQK0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cytochrome b pre-mrna-processing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007086</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670324.1">
        <property type="nucleotide sequence ID" value="XM_066811401.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044461"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037653">
        <property type="entry name" value="Cbp6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28250">
        <property type="entry name" value="CYTOCHROME B PRE-MRNA-PROCESSING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28250:SF1">
        <property type="entry name" value="CYTOCHROME B PRE-MRNA-PROCESSING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20180">
        <property type="entry name" value="UQCC2_CBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="116" mass="13487" checksum="0B672C417DD23765" modified="2025-10-08" version="1">MAKSAVSARNHILRALGKWPQDVIRPQVQFQDVLRKRFESKSTSGLSDQEELKQANALYSLLDNRYKKKYPITGTLLQPKSNPTYFTDLVKELQEAPNRSWLDRFILRIKGVVRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX67</accession>
    <name>A0ABR1WX67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002716</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670649.1">
        <property type="nucleotide sequence ID" value="XM_066807031.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040091"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8087755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="54607" checksum="C57E86733218627C" modified="2025-10-08" version="1">MPALLMTVVGGLVALGVFVAMHRVYLSPLRHIPGPAPAAVTRFWYVWRLLKGKINLDILAAHDRYGHFVRIAPNEVSVGHPDGPKKILLATLHKAEWYKIATFPDGRFFNTFAETNPKTKMELTRHIAPGYTMTNLLQAEQAIDSNIVLLLDWLDRFAECGDPIKLGGYLRYATNDIVGDVLFSRPFGFLKKGADIDGCLANNEVQIAYVSVMGFFRWVHVLLLANPVVTWLGIVPWGHTLNTAKKALQDRQKNPDGRYDVSAHWFRMLNENPGRMQRHEIDSAAFNAISAATDTVAATIQAFMYYLMRHPECRTRVQAEIADAGLQDRVVSYADAQGLRFLQACVKESLRLFGPVTMGFPRVAPKGGIAIGDQTFPEGTILSVHPWVVHLSKEIWGEDAREFNPDRWMGDDVARLEKHFIPFSLGYGSCPGQNLGRIELSKICATLARSYDFRQVDPEQQMRYEAYFGLTAHMPACYVKRQNMGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXG5</accession>
    <name>A0ABR1WXG5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670745.1">
        <property type="nucleotide sequence ID" value="XM_066807127.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040187"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="438" mass="48222" checksum="6B0D5E4E1E3AD489" modified="2025-10-08" version="1">MTHRRDEPFSFHGIVLPWTDPNYVPRITTGFSTACLVQSFEDGKVYIHKWMVPVRFFLPPEFRASSFHPQQWPGQILPPNILHPAYVLPDEPYFQKIVCAEATPLPPFLPHIQVYSTYIDLRQRAPNGGSLYDLVQKHYLAGRAIPEPFIWHKACAAPAGGGSAFTCTATVAGVMFPRTQKQVPTLRGKRGKSYFTGTSQLQSLKSIYLHYQPRGPGATPNTGQIRNALPIVRIGDWDHSCMEGDRRPRITAGRFGQDPVEWEDAMAFGQIARSLLMAHVPLWDPVGNPCPTPGQVLVEGLGWDERPDSRQIAFIPQPANFQYTQRLLIMLQPFEIPGIQYTGVPFPGANRFGGPAPAPNPMTGVPHPFPGSTPQPNQAGLPGPVLYETDINYICNYASAGASDGAYARWQNTAALMADGWGDGLAAKAGRWLDAVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXG8</accession>
    <name>A0ABR1WXG8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670708.1">
        <property type="nucleotide sequence ID" value="XM_066807090.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040150"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="186" mass="20439" checksum="86779558D2A282DA" modified="2025-10-08" version="1">MTSMPPNMICGRQTGDGTGPIAIGKTRLSARRMPPQPCTAWRDPSRPLAGGALALWALLGSPLDIAARRHRFGIRGPAASLFVVNGLTLGTALFTYRCRRRAALLPGWFARASGLLRVLDRYNRSSRQPSKGGWMDGWMTYQFHHDAGVGDGMNATYSLRRKSIKTKTDRLVTEAENEEADGRTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXK5</accession>
    <name>A0ABR1WXK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002853</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670786.1">
        <property type="nucleotide sequence ID" value="XM_066807168.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040228"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677:SF8">
        <property type="entry name" value="CYSTEINE SULFINIC ACID DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="504" mass="53565" checksum="56D3BCE227E83F32" modified="2025-10-08" version="1">MGSIAKELNGSTGEPLQRADELEDLIDAVKSLIVPYVRSADQAASFKATGQVSKGANGQPQNVLVDTHKPAELIEKLKLSLPEAEGRGEEGLLATIQDVLKYSVNTWDQGVGVVSELLLSILNTNVHVYQVSPVLTLIEKTTARQLANLFGFTGPRAGGVSCQGGSASNLTSIAIARNALYPECKTSGNGARRFVLFTSAHGHYSVEKAAVTCGMGAAAVVPVAVDPRTGCMDPAALRATVLRVHDDGEGRTPLYVNATAGTTVLGSFDDFRAISAVCREFGLWLHIDGSWGGPCIFSAAQKHKLAGSELADSITVNPHKMMNVPVTCSFLLTNDLAVFHKANTLPAGYLFHGAGDDGEVYDLADLTLQCGRRADSLKLALAWIYYGAAGFEKMIDHAFSMAAHMADLIDAAPDFELASSNPPPCLQICFYYAPGGKLAETKEENTRRTREMVGLLIGRGFMVDYAPGPKGSFFRVVVNCQTLKGTVEGLVKALGEVGKEVVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ00</accession>
    <name>A0ABR1WZ00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mannosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_003338</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the eighth mannose residue in an alpha-1,6 linkage onto Man(7)GlcNAc(2)-PP-dolichol to produce Man(8)GlcNAc(2)-PP-dolichol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29535"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19518"/>
            <dbReference type="Rhea" id="RHEA-COMP:19519"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132517"/>
            <dbReference type="ChEBI" id="CHEBI:132519"/>
            <dbReference type="EC" id="2.4.1.260"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:29536"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671271.1">
        <property type="nucleotide sequence ID" value="XM_066807653.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040713"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF1">
        <property type="entry name" value="DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="347"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8088377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="557" mass="61148" checksum="991C77AF5DE6F7AF" modified="2025-10-08" version="1">MGKTGEAVLDTLLSLTIPALVILHLIIAPYTKVEESFNIQATHDILVYGTPTSDVHRRLSARYDHFDFPGAVPRTFIGSVLLAGLSQPFIYLAGFRHAQLVVRAVLGLSNAGALLVFKSRVEQAFGKPTARWYTLLQASQFHVLFYASRTLPNMFAFALSESMNHFGRAMPCGHRLFTYATAVFRSELAILLTTTTLYTLLMGCTTIRRVIPAFLGSFAFSLLASVPVDSYFWQKPIWPELWGFYYNAILGSSSEWGVSPWHWYFTSALPKIMINPLTWAVLIPYALFNKSTRLSAQCLTLPGLLFVAIYSIQPHKEARFIFYVAPPLTATAALGANYIFTRRAKSVIYAVASLVLAGSVALSFVGSTGMLMLSSLNYPGGEALTQLGSVIDMTSPSPDVKTVTVHTDVLSCMTGVTLFGQLSYPKKTLNPAADTVSFVFDKSEKPALLQTPGFWGKFDYVMVEDPSRVTGSWETVGVIEGFAGVELLKPGAEAAGSDLESGNGNKDDLVLGRGALVRRVRDAVRKLTGGWWIGPRMEPKIQILKRLRAAPRKEVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ14</accession>
    <name>A0ABR1WZ14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671298.1">
        <property type="nucleotide sequence ID" value="XM_066807680.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040740"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF12">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="22"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="555" mass="62052" checksum="DCE87AD0EEDD9EE9" modified="2025-10-08" version="1">MWLINVDTLELEHVLDHEATEYAILSHTWEDGEVTFQEFRDRHDGDVAATVRVKKGWRKIERFCALTRGYGGRRLRYAWVDTCCIDKTSSAELSEAINSMYRWYADSAVCFAYLGDLAPRDYHNGNKGSQNGDPDADADGDVGGVAAADKEGGEGDARAAPSAPGLVDDIFQCRWWTRGWTLQELIAPGKLIFLDRDFNLHGTKLSLQSQIAERTGIEKKILLHRKPLSSAHVARRMSWAAERLTTRAEDAAYSLMGIFDINMPLLYGEGVRQYRGILARHPREFLSAKTLGKQPGELHRGELSVTNKGIRIDGTELLHAPALGIFLRLGRLQPDEAQPGKGNMYVQLAKTMDGYVRAHADRVFLWSGLERRRHALAAARERLRRVGPVAERPGQGREAAQAHGAVRGRPSRRTIGNNDDNRKGGGGRPVIRLGQATYPRHFWDRHESAALLDFASQQEGLVELVATLADGHTTGRLVLAWSSYMAGVEGRRNKRQNALKYALLDARSPHWEAVSATLRGLSGGRAVDRLLRFWDVADYPKYSFLFLEVSPFSYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZG1</accession>
    <name>A0ABR1WZG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_003526</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Vacuole membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671459.1">
        <property type="nucleotide sequence ID" value="XM_066807841.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040901"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17483">
        <property type="entry name" value="MFS_Atg22_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044738">
        <property type="entry name" value="Atg22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050495">
        <property type="entry name" value="ATG22/LtaA_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="4 10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="408"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="547"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="576"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="32"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="244"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="618"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="247"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8088565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="649" mass="71049" checksum="FE45E0C62DC98BAD" modified="2025-10-08" version="1">MVPRNEERLPPRPPFLSIPSFAKSFRSYTSSFEADDERSTSESDTMSPSPSTENGERDGGRYPGEDTRPTTGKELAGWYMYAFAAETYMICASFIPILLESLARDNGVLLSDRKTPCPSSDTKHAKGEESQCIVNVLGVEINTASFTMYTFSISVLLQALLVVSISCAADHGNYRKRLLLTFGWVGSICVMAFIFVFKEIYVLGALLAIVSNVSFGASFVLLNSFLPLLVRHHPKVQEAAVTDVVTPDDRHGTEAESPQHGRWTTGEQPRNNSTTALLPQDDAASDYNELVRTPTHSELTSIELQLSTQISAKGIGIGYGAGLFVQCMSILILIAMGSSTWSQRVVLLVIGSWWAIFTIPAAMWLRPRPGPPLPKTNGNGRWAWLSYIGYAWKNLYRTIKLARRLRDIVLFLAAWFLLSDAVATTSTTAILYAKTALGMKPWALGMINVISTTTGVLGAFSWSFVSRYFKLAPHHTILACIALFEIIPIYGLLGYLPFVKQWGVIGLQQPWEMYPLAAIYGLVLGGLGAYCRSLYGELIPPGSEAAFYALYAITDKGSSVFGPAIVGAIIDASGEIRPAFWFLAVLVGLPAPLIYFVNVERGKIEGEKLAEVIEGFKSQEDSSNLSHADDESHGMLASYDGDGDDGRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZG2</accession>
    <name>A0ABR1WZG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671445.1">
        <property type="nucleotide sequence ID" value="XM_066807827.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040887"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="27930" checksum="C07E13D957CE9105" modified="2025-10-08" version="1">MAFIHDDQPGLEVKPAMQPGLEVVPEPEAPQVVSGPMSQKPWDQRSPNSLPYQQQHQQYQQYQATSPVHEYHDQSPYSQYPPQPPSSYPGAMSDWNGTVGPSPSERAAREPTIMGIRRKKFWLIVGPLIAVFVIGVAVGLGVGLGSQHGSNDSPSATPSPSVVTSIVCPANNGSFYESNDKTKRFQVACNLDYHSGGGTQDMGDFQTATFEDCLNGCAANDACVGAGWGVYNGATRCWLKSHLGSNQMAPNWMFGVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZK6</accession>
    <name>A0ABR1WZK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FabD/lysophospholipase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003531</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671464.1">
        <property type="nucleotide sequence ID" value="XM_066807846.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040906"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="6">
        <location>
            <begin position="36"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="4">
        <location>
            <begin position="40"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="103"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="498" mass="57037" checksum="5185ED29AF2B5A99" modified="2025-10-08" version="1">MRDSSFRPPMEPMSEENAEASEAGTAADPWDENITLGFDGGGIRGYWSLLVLQSLMKKIKEIERGHGTRHSFHPCEPPEVFSQLGGGDFTPFLPCHYFDLIGGTSTGALIAIMLSQFRMTVEDCMREYENMGTNIFGHPRMLHAVNVPIITRTRFSTRRLTQAFEQVIRRRLEATEEFTSSVEFQTYTGTCRGIALSMTDGESELLCHIRSYKRPGPVPYSTWSILEAARAATAAPLYFKRFSKSLTPRQLQTLARVPTSQTLSSFVQSAEQQQQPKPEGTRFHLIDAGFGIENNPCEKILHEMRTMQFRSKPILVSIGTARPGHPDEEGRRRTLFSTVKRAFRTLGDPENWHAHLQGRAEQGDFMYFRFNARGTLNMEMHEWIPKKSGRKTIDKMRAAFRDWADTEEAQDQLRDCAEQLVKVRRARSNKDRDEAKWARYAVGRYYICEDNGCYCHNVKFPDRSKFEGHLAHHAGGEQRIEDVVQRAEREWEYRSASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X084</accession>
    <name>A0ABR1X084_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial low temperature requirement A protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671678.1">
        <property type="nucleotide sequence ID" value="XM_066808060.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041120"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42101">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42101:SF1">
        <property type="entry name" value="LOW TEMPERATURE REQUIREMENT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="548"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="581"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="693" mass="77058" checksum="77B65B8720473DC0" modified="2025-10-08" version="1">MPTGSDLDYAGERLRLIASRIEDPRNPSNHASGHGHGHGHDDHTAHTASIPAAPNMDVPAFKKSHAASNFELFYDLWFVANLNVFAAIHGITDGAALRSFMGFLLMLWTTWLVTSIYDVRYTSESILERCCRGAHLGVMTGFAVIATKFSPDDQKPAVYQVMSLFLAVSRLVLTLQYAMSAWQARKFTHGRRPLLATAAFHLVAAGAYTIIAYRYVVRDSSRGYIAWYVIGVVEMALHLICSQFSPVLTFIGSHFGERLNLLTLIVMGEGVIILAKNITLVVKDTYLKDSTAKLWTDVVPQKGPALIGIVTAATALIYIIFQLYFDWMHGEDESMSTRHQVLWAVVHLPFHIAMVLLVEGSNQFISWWRIYESIDKASDALLDVRNMTWTSAAVAKELDKRVMKWLSKYPPPDIINSYNGVNATLKDIKALPDSFWGNQTISDDDPIMIQWSDDVTRLFLTMVSGIFNNFKIEAPESKKGGDQADDKTAAAAHESYDVLPQSDMIDGIAMRFKLVFIYTFLCAGSVLFFLTVMHCISKQRGWTPFNIARTGVCVALALGLALTATVATNEDAVDTFIGSPWMLPTITLSYFIALVLTHLPHPRKFGLGRFGRGTYKEVDHERQQHNGESVPLKQMATSIVITRPSQEYDPYESRTGVFMSVKGGMPPSPGHNAHIDAHDPMQTPPHSSMPGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0D7</accession>
    <name>A0ABR1X0D7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003817</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671750.1">
        <property type="nucleotide sequence ID" value="XM_066808132.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041192"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF2">
        <property type="entry name" value="WW DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G06520)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="646"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1191" mass="128982" checksum="A63661D06B8FE4B0" modified="2025-10-08" version="1">MDRQRRGDEEMFLNKPSDDCDSPTIEPLRIFKPQSPVPAAERPQNRFKYPAPPSSQPSFPLPPGASSSAEPLPYPDDDDLRPSQPSKSSRLPYPDDGPRPSSGRTYSSPSSSVHPDRLNDTTPRLDTSPIDKRGPGLAERRGTAPKPLPGALSPTSPVDQDGLFAKPLAGQHKPAPSVDNFPDYHKKPYYPPPRGSSTSPSNSSNHSSNSNARPQQPDDGLLKMPGASSVNRFASTASTSTTRANRGSPPPPETPIVEPGVVPGGGIEARYAASGISGTATLNSLQSAAASQRLAQYSQHPATQQQQPAPNRPWTPTETPDQQPHGPPTVYQGANPVSNTAQPASNSQPRPSTSSNAPALQESVLEQDFRRMQMADPPPAYSSINPSGGSQYPAEKQRPNAQPAPASTSSPAQSVQSVTIPAKKQQDPAAAGLASPALQHPGHPAFANDPRPESSTAATPAPQPVQSTPSPFQGQGPSSPPPLPEGHAMGVPQGPNPLNHETAPLSPTASTYGNPLGSPMFGKPSALASPMFPPHTPGYAESIMSVAASATPSAAGFSGPPPSAGVDMYRVQPTNGVYFGPYLRYVNMDVEKGIWLGSILIVTDGQQPPTIHIHLSSDLSPNPRQLVPHCIHTHQRWQFFKYDIDLQMNDGPTERWTYAITSHLGCTRYEFVVAGRQETNWRFVAHSGNDFAASTSQNERSKLGGVGFMWKDVLQKNVDCGGFHVQLGLGDQVYGDRLWKEVPLLKQWLAMQGKENRRTSQWTARHEEDVNHAYFHFYTSHFDQPFLREAWAQIPHVCQIDDHDIFDGYGSYPDYMQNSQMFKNIGRIAIDMYLLFQHHTTLEVLRNVSHDLDLFTITGQGWHFVKYLGPAVVVVGADVRSERSQSRVLAGPTYQGLFPKVAMLPPSVQHCLWMVSVPLVYPRLDTVESLANTFATGKKAVNTTYNVLGKVTSSVAGIVGGKDMVASGFSSVKKAVGKSGLMGNVVNQFGDLDISEILKDMWTHESKDLERTYLIRTLQGIAHQKGIRMTFLSGDVNSCGAGLVHDPTHPSDHKTMYQVITSPIVAAPASNYILKMLHSNRTHYIPANGNKSSPNDVSDTKEDMMEIFHTDASGAPRELKKLMGRRNYIACVAYDPEAIAGTQYAASIANGQQQGLSKLSLAIDFIVQGDGAFTSPTKYGPVIVPHLEFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0R7</accession>
    <name>A0ABR1X0R7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003959</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671892.1">
        <property type="nucleotide sequence ID" value="XM_066808274.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041334"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF181">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="483"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="51"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="519" mass="56886" checksum="A28E63C4EACA90B3" modified="2025-10-08" version="1">MRLHTLRELDNSEGTVQLHKGGNRTLELVPRPNETDPNDPLRWPKWKKHVAFGSVCAFAFLTNYGIGGLAPAFYILSKEFDKTVPETSDLLLWPILVLGAFNFFWVPVANYIGKRPVFVFASLLLTLCSIWGATADGFKSLLWSNIIGAFAGSSTEALGASMVNDLYFLHERGSKMGIYTNAISGGNTIGPLFCSFVLQGLSWRWHKWITTILTAITFVGVLFFVPETSLFTCWEPAGPSPTPEKSRATASGHPSTCSRSRSPERYAVAELPKKTYRQEVALWTGVTPNTTLLKSFVRPLPLIVYPCVIYAFLGYAVSLVLTVAVNILNPFVLQAPPYSWSPLISGLINIAGFLGNVCGAYAGGWLVDVWSDWRARKNQGVFEPESRLALLVLPTLITGAGCLVFGYGVERALHWTSLFFGYGMISFALTAVPTITMAYVSDCVLAVNADALMLVNGLKNIVAFGFLYGIVPWAEEAGYINCFGTQCGIFVGIIAIGAVLLVMYGARIRHVQASWRIIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0S8</accession>
    <name>A0ABR1X0S8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome biogenesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003936</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in ribosomal large subunit assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RRS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671869.1">
        <property type="nucleotide sequence ID" value="XM_066808251.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041311"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007023">
        <property type="entry name" value="Ribosom_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04939">
        <property type="entry name" value="RRS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="86"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="175" mass="19819" checksum="BBA960FD765D13E4" modified="2025-10-08" version="1">MAATKPKLDISVDKPTPYTFDLGLLLANDPNPLPPSTSSGDLEERLAATARDGAQALINQLLTTLPLSSTPAGVLLTLPQVSTRLPREKPIPAQKEKTKWQQFADRKGIKPKTREQRREKSRTFNEDKGEWEKTWGYKGKRKEGVVPDDWVTEVTEKSEREAEDKQKQKKKKRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X180</accession>
    <name>A0ABR1X180_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATPase inhibitor, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004107</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Inhibits the enzyme activity of ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ATPase inhibitor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672040.1">
        <property type="nucleotide sequence ID" value="XM_066808422.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041482"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.500">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007648">
        <property type="entry name" value="ATPase_inhibitor_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04568">
        <property type="entry name" value="IATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="59"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="99" mass="11316" checksum="8F583182BE125C94" modified="2025-10-08" version="1">MYRQYIVKASSGLTTYAPRRAFATSLRVMGEGDTGAPRLGGSNDPFVKREKANEDFSIKRREKEKLLELKKKLAQQQEHLKQLSDHIDDLTREQGGEHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1M2</accession>
    <name>A0ABR1X1M2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004256</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672189.1">
        <property type="nucleotide sequence ID" value="XM_066808571.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041631"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="173"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="257"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="960" mass="106089" checksum="203F4F87E4880713" modified="2025-10-08" version="1">MPILLTQAYSRNTLNAIYQITPTSSRIVARAVSSPLREGTFSNVRVTLWAQLASVYESPALDTNPGAPPTVVGKQPIACLNCAQAKTGCDKRVPCARCADKGLPCAARFARRSSKAALRAAAALQNQPPVPQVGATATMNPAFMDLDSIMKHESAAKPMVSPDAVSAIDPRIQQGESPHKNNSPANSHPGTESNFPSPHTKVDLDDLMLSSDFLHQDHNYNDMLVWPEYSLDLDMYSATNVPLGTADVPMPPFAEMSDASSNSEQMSSSRGSIHTRSTSTSIMSNGEYEPTVKPTDVTVSSPNDTTDLEVVLAAEAAWPLARCTPPVYSGTCPRTAIVHLESLEQKSKQENTWETLERYLEQVDWDAADLASVIPLHSRTRDNMLAITQTFLHKALEIHRGGLSGYSKDRFSGPGLATFLVLPPSKILEYFLRSYVRSLSFFYSLVSTGCVDPNEMVQNNKASTLLVLLMIAQGASAVPTAEARALSAGLVETCRISLFDIVGSFGIPSWKCTLTLWAPQIEKDIEMCADPITVRCSLLFTLLGAWSGDKWLMDISLGQRGMYLSMLKHAGMLDAQPAMIPNFHGSLELQWRDWLARETQNRLVYNWVMVDQELSLFHDTAPILNISELCAPLPGPDLLWMSANAEQWQQAMQSLYGCTANVNPQLLNTPSLSPSLYDVFQDFLHENLSRRQNTLSAHQLRLLLHPLQSLLCHLRQMLSCFSDVLSTRRTASRTVTKASTMLRLEEVQALLQSWYELSMAVYNSNPGCSVSKTNLVLYHLISLNAVTNFPEIERLARREGFDGSYWELSLRHKRCIYQREESIFHCGQVLRLIRTMPADRRPTWWSAALYRSALILWTDSVSRLDPSFQKRDEGSPVAIDQVTPEDPAVIAYLWNGDGIPVLSRGDGSTTALDKPVDVLLYAAKSIEEGVSCRLSDGIKRKLLALGNNWSIDGLTSTSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2M9</accession>
    <name>A0ABR1X2M9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C4-dicarboxylate transporter/malic acid transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672533.1">
        <property type="nucleotide sequence ID" value="XM_066808915.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041975"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09317">
        <property type="entry name" value="TDT_Mae1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030185">
        <property type="entry name" value="Mae1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162:SF0">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="46088" checksum="D85D1FE3419BAC4E" modified="2025-10-08" version="1">MLHRKKNHAGREELESPQDEPHHRHLPFRLRVTRITWQWFPSTMSTGALASLLGQQPFTFPGLTTIGKIFFILDMVLFLAFSSLIAVRFVLKRHAILASLHHPSESFFFGAWWVSLALLLNCAASYGIPGLGGADGGGAWLVAALRVLFWVYFACAILVAVLQYYIIFQTEHLRVSDAMPAWILPAYPFLVSGPLAAQIAKTQPDATAALQIIVAGISGQGLGWILALLMYSVYFTRLIRSDMPNPSVRPGMYVSVGPAAYTAAGLLALGQQAHLQLPAGFLGITSLAVGDVWLAAALPAGLFLWMVAIWFSGVTTLHVARDARRMRFSLQWWAFVFPNAGLAMATIQIGKALGSHGVDVFAAALTVLLVCFWFLCAAMHVRAVWRHDLLQPGRDQGVDDVNAVHDRAKEEGEEDEKMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X380</accession>
    <name>A0ABR1X380_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672767.1">
        <property type="nucleotide sequence ID" value="XM_066809149.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042209"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="174" mass="19190" checksum="8A5AA19145AC92C1" modified="2025-10-08" version="1">MMEEIDQLFDVGKDILNLPEDAKQRYLHDIPKSFLGFKPRGQAKIETNEPDRFEWFNLGQDSIMGTETTQPIPPLVQTHMSLFASFLEHGQSILATINTTLATQLALPPYAFACLQTPTRPSGTVVRIIKAFAAERDEDVRTSMIHHTDFGTITLLANVVGGLQVLAPGKSPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3A8</accession>
    <name>A0ABR1X3A8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BRCA1 C Terminus domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672760.1">
        <property type="nucleotide sequence ID" value="XM_066809142.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042202"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="207"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="359" mass="37278" checksum="D084B75910FB71C6" modified="2025-10-08" version="1">MDNNGRGAGMVPPPMPPQSVGTAVKPKTSAGVGGRGGGGAATTRSSLVVSPTKAAQPQFGATFDPWNSSSSGHQRAENRLGASTGWRDSRNAKLHSQFRGDARRVSDAVGAGARDWDPKLQAVVPPELRARARCSVADMLAKPGTMQRSLSSLSSTSSPSTSPRVGVVTGTADKDVTTTGAESGSAEHARRTDEANKEISPDQQDQGPGRLFAGVVVYVNGSTHPQISDHKLKHVLAEHGGRLSSRLGRKQVTHVILGRPAGGGGLSGTKLQKEIQKVRGAAVKFVGVEWILESIRAGKRLPEARFSNVKVASKGQQSVFGLYSKPAPLPAAPAASAAESCIGSLETLGDEPPPSAQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3R3</accession>
    <name>A0ABR1X3R3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005015</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672948.1">
        <property type="nucleotide sequence ID" value="XM_066809330.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042390"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR PBCR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="145"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="270"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="735"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="812"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="747"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="761"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="812"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8090054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="946" mass="103984" checksum="8288ABBC18EDC95F" modified="2025-10-08" version="1">MDEHQIDPRLREDSIVVTNPTDAQQPPLQPPPAPAAAAAAAAAHQHQHHHQHHQHPQQQIYQPSQPPSNNHSYASQPPADVAASIIESPSEGPSPVGPPSAQTYGGPQTPLTPTASHLALNHETPGTDPNGGNPNDPNDPKRPRACEACRGLKVKCEPDPANPEGPCKRCAKAGRNCVVTQPTRKRQKKTDSRVAELEKKIDALTASLQATRGGVPGGPAHQPSPEEQNGFINAQYQTAQRSWGPPPAQNPAHQYATEKHDHIFTPPAAAGQKRKFAESRDHSFDVARDSPGRSSKGHDYFNPDVVDRGVLTMDQADAYFARYNDHMIAHLPAVVFPREMTAADLRKSKPLLFLSVMAAASSEVYSVQRPLVKELTQIFAEKVIINGEKSLEMVQALQVSVIWYYPPEHFEELKFYQMVHVGAVMAIDVGLGRRRNNPKSRFVPYTWQNHPLRKDPLPDPSAIECRRAWLACYFLASNVAMALHRPNLVRWTSFMTECMDILESSPEAAPTDKYLCHLVWTHRLAEEVGIQFSMDDPNAIVNVAEPKVQYALRGFERDLAKYSENIPQSAKQPSLSLSFHVLSLYMHEIALYVEKPNEGMQNFNSDSLQDPVPGLNETLTAAHIGALSSCLTAIDGIFESFLSMDVQSIRCLPVFNFVRVAYAVVVLIKMYFSASTPNSELGKVINKDHMKVEEYIEKLLDKFRDTATHEKSRPAGKFLVVLVMLRSWFQKQGKSDQVKREQLATDAGNSNRPNENAASLPQQQQQQQHQAQQQNQQQHTPQQQHATPQQQPPNQYNPANTPLQLLSEIATGNQNNNSTSNNNNGAANTTTPTNLPPWLTGGTSGPQPFIRGGPAVEHDPNFVLGMQNVMPYLNNTLTSDFDYNSLGDGFEQAMDLTFGGFNTGAAPDDYMRWDTLIGSMTGEGLPGAGGNGGGGGGGPAVPFHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3T1</accession>
    <name>A0ABR1X3T1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672946.1">
        <property type="nucleotide sequence ID" value="XM_066809328.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042388"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="93"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="315" mass="34994" checksum="C2752E06821237F5" modified="2025-10-08" version="1">MPGPQLLQAFQEEFDRQERCACWPREYTDAVLHLRQPRERGAREARECLMKARSEGRVTVEEASFSRSAPRTGVIKVTAVYPSGNGDPNRPCIVFCHGGAMAGSDRYVGLHVNGPKWAEALGAVTVSVEYERAPENQGVGLARDCYEALVWCWENIEFDHGRLLLYGASAGGALAAGAALTLVHEQKTKTGLPELCGLFLEAPMLDWRCDTASMHRLSQNGPFFNREACAFAWQSVIQGKQVEFSDVVSPRRSKEERHCQTSSNSRLCRGYGPVTRRGGLLHGKIRKTRLHTPRISGGASRFRRHVTHRAYLSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4X6</accession>
    <name>A0ABR1X4X6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase</fullName>
            <ecNumber evidence="5">3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_005427</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673360.1">
        <property type="nucleotide sequence ID" value="XM_066809742.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042802"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF1">
        <property type="entry name" value="XAA-PRO DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="12">
        <location>
            <begin position="110"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8090466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="542" mass="60059" checksum="B9CA61BD7C31BC54" modified="2025-10-08" version="1">MELWARGKPPIARVPQAADGLKEAGEALLGQKAFPFLNRQMSSFVHLRFLSRCARVQLPLLATRTTSNSNFIRYFSSTSTFSFATTPRTSPTPTMTTKTMDVDKILAGKYPAKAHAARVAAYIRTKTDATGILYLEGAASGLLEDCDEPVPFRQRRAFMYLSGMDDVADSYLVHDIATSQTTLFIPPVDPEEVIWSGLPLSCDDALARYDVDAVLPSTELNAHLARLGAAQKDKAKNTNFSLLGEAVDECRVVKDEYEIALIRKANMVSEAAHQKVMQSVRQAANEYELEGLFLGECYKKGAKFQAYPSIVASGRSAATLHYVHNNKEMPGKDLLLLDAGCEWKLYASDITRTFPISGKFTAESRAIYDIVLKMQLDCIAMLKEGVAWDDVHLLAHKILIDGLLSLGVLKGDKDEILKARTSAAFLPHGLGHYLGMDTHDTGGHPNYSDPDPLFRYLRVRRNLPAGSVITVEPGIYFCDFIIRPYLKDPKHAQYIDEKVLDKYWDVGGVRIEDNLLITKDGCENLTDCPKNPDELEKIIAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7I1</accession>
    <name>A0ABR1X7I1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673413.1">
        <property type="nucleotide sequence ID" value="XM_066806117.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039177"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="85"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="401" mass="45365" checksum="17BF5977C7356E0C" modified="2025-10-08" version="1">MSSTSATTTTAGVISLNKKAAVESTEPQFPDVNTIRKAIPAYCFQPTVARSMSYVVRDLALAGALVYGALTFIPQLSNPWARAAAWAAYTFAQGLVGTGLWILAHECGHGAFSLHRGVNDTVGWALHSLLGVPYFSWKFSHARHHQFTGHMHKDMAFVPATREDHERKRATQWWHSDLLEDAPAFVLLKLLGHQLFAWPTYLLFNVSSGPRSLQPNKNTAWYRVSHFDPFSAVFRPNEAIFILLSDIGLGLVGFGLYLAAQQLDATTVFLLWGIPWFWVHHWLIAITYLHHNHPDVKHYDENGWTFVKGALATVDRDFGWIDRHLFHGIIGTHVVHHLFARIPFYYAEDATEAIKPMLGDLYHQEKGSFYGDLWTTFNHCKFVENDPAMPGVMKWNKPRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7J9</accession>
    <name>A0ABR1X7J9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001796</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673407.1">
        <property type="nucleotide sequence ID" value="XM_066806111.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039171"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039226">
        <property type="entry name" value="Ski3/TTC37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040962">
        <property type="entry name" value="TPR_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704">
        <property type="entry name" value="SUPERKILLER 3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704:SF7">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18833">
        <property type="entry name" value="TPR_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="451"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="648"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="973"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="314"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8091435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1399" mass="155440" checksum="513F193C1FB5C093" modified="2025-10-08" version="1">MSKQLKVVREAIKQQKWDEAVQQAQDIIDNDSKSYQAYVFLAFALDKKNKLADAEKAYETATSLRPADPQVWQGLIKLYEKQGDTKLLQYKQAAPKLAAIFYEQEDMYKCQDVVDKFVDFARSQGSRTQYADALEVMLPGSPIYSALEGRFPHPAKTYEIVAQILETDEKKRINTLIGERRTRIGAKVSEVTVEVNREVLSQSKLGHIYEQLINWTNDDDTRRQYEEKLLQFRYDRLMNFLPGPEKQAELAVVQKLAADMVIIKHPYRLAWDVAINWQDHEEIKDYNVDTLLDYCSLFPETDLCKILTGYMTSSISPSPRSQTPAESQAEDESSEDDEDGGAPTLVIPFTDEDRLLMMIDGISTSDSLLAHRLMGEYYQHLEEYESNVELMRKAMKLLGQRAQKIGKSFNHTNQAYMLYLGTALVFYQSPRHHGEAKSLFDKILEVNPSSTPAQIGVGLIYEEEEEYDKAISFLEKALERDGSNLRVKAEVAWLYSMKGDFTRGKSDLEDILGLMTSKGSTTSKELLAQTQHRLGVCMWNLDTSKAARKSRDGAYACFLAALKSDISYAPAYTSLGVYYADYGRDKKRARKCFLKAVELSSAEIASAERLARSFADDGDWDRVELVAQRVIDSGKVRPPPGSKRKGVSWPFSALGVALLNKQDYHRSVTSFQSALRMAPNNYHSWVGLGEAYHNAGRHTAAKKAILNAQRLEVALGEEAPGDTWFTKYLLGNIERETGEYDNAILLYREVTKDRQDEAGVMLALMQTMVESAHDCVENGYFGKSVSLATETVEFAQSSSDAVSGTFNFLEGARCIDQFPVDAIKTLVGQGDDHDAAYSIMQDVDGISKDLGFADGLSPPNDKLDVELTRCLHAMILAHKRAAHLSSHDVHAQSIAFYNLGWAEYRAHSCLPAELRIKSSRYHRAAVRCFKRAIELEAGNPDFWNSLGVVTSEINPSVAQHSFVRALYLDERGVHVWANLGALALLQNDLQLANEAFTRAQSTDPDYAHAWLGQGFVALLYGDVKEARSLFTHAMNIAECSSAVTRKQFGVSIFDHILKSPNGPKLNDLIQPLFGLRQLQRLQPQDMMYGHLSTLFLERVSDHARSIGALEDICGKLEAHYEENESPQVLGQFALAETDLARMYLASGKNEEAAECGETALQLSSDDSGNELTAEQRTRARLSAHLTVGLAKYFSKSPSEALTYLEAALEESNSNPDVICLLAQVLWAIGTEEARDRAREVLFSVIESDATHVQSVLLLGVVALLDGDEESMEAVMAELQALRASDKLVESEQAKIGEVLGATSFLASSSKGTDEEDMVSQSQINTFLYPNLPHGWTSLSELGGEDHAAEVALQVASLKIPPAGPLDTREFARAFAGTGVAADAQMAAFMAPSLGTGWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8N3</accession>
    <name>A0ABR1X8N3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002089</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673700.1">
        <property type="nucleotide sequence ID" value="XM_066806404.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039464"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF29">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="38"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8091728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="542" mass="60823" checksum="61E2EAD6F7E79495" modified="2025-10-08" version="1">MGVIKTGHAGDPVVTRLLQEDTTPWYKKPNLRLMYLWLFCCCMGVEMTSGFDSQLIGTLQFSDDFNKYFGNGYISSKTGKAGIEPAMLGFISSCYQLGSILAVPIAPWFNQRFGRRWGIMAGSIIMIVGAVLQGFSQHVGMYIVSRMILGVGILFAIISGSALIGELSHPKERAVMTSLFNSSYFIGSIMAAAIAIGTVEIKGDWSWRLPSLLQIVPSVMQICTVFLLPESPRYLVSKDKDDEAFAILTKYHAEGDASSLLVQAEMAQIKSTIKLEMENSKQTWAVMWSTAGNRRRVFISVFLGLFTQMSGNTLLSYYQNLMFEMMNFTENAVKTRINIANQCWALLNATALALVVTRFRRRWAFMASSTSMLLVFSAMTVSFKVLRSAKDRGETNGAASISALFFYFAYSPCYNLGNNALTYTYLVELFPYAIRSRGIGIEQVFGKAGGFFSTNVNPLALDAIDWKFLAAYCGWIAFEFIFQFLFYPETYNRTLEELTFLFEPDELNKQVVAATEKQLQTAEHQHTTTIEEHVDYPKRSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8S5</accession>
    <name>A0ABR1X8S5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Estradiol 17 beta-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002232</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673843.1">
        <property type="nucleotide sequence ID" value="XM_066806547.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039607"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF236">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="326" mass="35607" checksum="BD93C77534CF76FA" modified="2025-10-08" version="1">MGMITQFFPQKPTFTDQPLPDLKGKVYIVSGANTGLGKEVARSLYAKNAKVYIFARTESKANQAIADIQKAHPSSSGSLAFIPIDYNDLRAVKPAVDTFLRQETQLHALFNNAGVMAGSADVPKTVQGYEQQLGVNFIATYLFTKLLTPTLVATAKSAPVGTVRVVWVSSLSTEMYAEKNTAFDMDNLDYHVEKPVLYKYGISKAGAWAYAVELAKRHQADGVVSIALNPGNLKSDLFRSQGRAMKIMNSMILYPVPSGAATQLFAAFSPQVTKETSLSGSWVIPFGRVAAIRKDLINATKSAQQGGNDGTCKFWEWTEGQVRQYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X907</accession>
    <name>A0ABR1X907_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysophospholipase</fullName>
            <ecNumber evidence="6">3.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002363</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the lysophospholipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673974.1">
        <property type="nucleotide sequence ID" value="XM_066806678.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039738"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002642">
        <property type="entry name" value="LysoPLipase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728">
        <property type="entry name" value="CYTOSOLIC PHOSPHOLIPASE A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728:SF40">
        <property type="entry name" value="PATATIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01735">
        <property type="entry name" value="PLA2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51210">
        <property type="entry name" value="PLA2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045007571" description="Lysophospholipase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="domain" description="PLA2c" evidence="8">
        <location>
            <begin position="328"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="548"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8092002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="914" mass="101189" checksum="7A0D676EDC02EEC0" modified="2025-10-08" version="1">MRFSNIIALAAGLLGLAQAAPALEPRIPKNMKPTTGEWKMDKAPNSSPQLARAFNWVRKQDNALTGANNLLVAAYYDKSTESVYASTIPRGNWQDLMLGDKKHGLIWRAHYQHIKKARADAEDGAYFWMEVSKNMQPAKDVPILDQIYGNGQKKGPKVAVWGVYGSSKDKVKKEAGTPIASCDGCKQLAKELGVYYEDPQVELAGAAMVVLKTIRRSPTYLYLKAYCLCALVTLFKAAPVSSQLPHLQQRLQRLHARKLKTITLKNWRTVHLPPRDLSLFALAAPVTGVTNVDSSISSIGQRWKRRVFDFAQVRELLRRDEKDVKVYPETSRDATVRRSSCVHPKEKEFTRLRTLRISSKGDDSLHKFLGLGPGEIVDPRDVPLIALGGSGGGYRAMYGFAAFMAASKKLDLWDCLSWTAGVSGSCWALAGYYTIARQDFSRLMRHYLSVAEELTHPLSLHALDIVARSSQGVYFLLGPLVRKAQSGAIGLGIMDLYATLTSTYQLLSREPGAKLSRATFQFSRVWEHAGIDRGLEPMPILTAVRKAPKNAPGVKPHGDSSLSKGQPPGQALVQHATAVSDTMPKNRDGIHVTGRKAAASDSPPEAQAYVPTWSYGRTFVSGRSVASRRLPEQSLSLMLGQCTSAPAGPLTGYISALLATLPQGTTMTRLLLLFNNYVLRPLTRRGFLWGNPIRAGHDPNPFKGFDGARPEEWEAETRHRLMDGGMSNNLPNHILARPDREADIIVAFDASSDIQSSHAERRLHNFAEDCHMSLEDITGELYRPTPKYVAFNQVPTTDATSTAATAAETEAKYLHRYVKVFKGIRQDRGKELYIIYCPLLPNGINPGFDPSTASFSTSYNLVWKPEQVKLLFKTAEANLSEYAIHAIKRVTRHVYEENKKRRSGCLSNPGNRCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X981</accession>
    <name>A0ABR1X981_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosome assembly protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673910.1">
        <property type="nucleotide sequence ID" value="XM_066806614.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039674"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16268">
        <property type="entry name" value="EF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056752">
        <property type="entry name" value="EFL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF3">
        <property type="entry name" value="ELONGATION FACTOR-LIKE GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25118">
        <property type="entry name" value="EFL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="2">
        <location>
            <begin position="17"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1035" mass="114330" checksum="EFDD440ACBBB3781" modified="2025-10-08" version="1">MPVVSPEKLGRLQSEPDDVRNICILAHVDHGKTSLTDALIATNGIISPKMAGKIRYLDSRPDEQLRGITMESSAISLYFSMLRRSAPDATPEAKEYLINLIDSPGHIDFSSEVSTASRLCDGAVVLVDAVEGVCSQTVTVLRQTWIEKLKPLLVINKMDRLVTELKMSPTEAYQHLSKLLEQVNAVLGSFFQGERMEEDLNWRERMDERVAAAAAKEKEAAYQESESDELQFQERDDEEIYFAPRRTTSAIDGWAFTVRQFASLYEKKLGIKRNVMERVLWGDFYLDPKTKKVLGRKHLKGRNLKPMFVQLVLEQVWAIYAATTGGDNGRGDPALVEKITKSLNLTIPPHIARSRDPKVLQSTIFASWLPLSTALLVSVIESLPSPRVAQKERLPETRQGASHIDANVKNAMINFQTSKSDPVVAYVSKMVSVPESELPANKRRGGQLSPEEARELARKKRAELARAQQAADTNGANDLTTAIEDVNLDDVTPQLDEKPIDPEHLIGFARMYSGNLSVGDELYVLPPKFSPAHAHAAPEPQKVTVTALYMMMGRNLESLNSVPAGVVFGIGGLEGHILKSGTLCSQLDGAVNLAGVSMLGQPIVRVALEPVNPADLDKMINGLKLLVQSDPCAEYEQFESGEHVLLTAGELHLERCLTDLKERFARCDIQAGAPIVPYRETIVRAEEMKPSANKELGRGAVVGVTSSKQVSITLRVRPLPDNVTEFLLKNSSAIKRLYNEKKAAAEGIEISSESGDVQEDVDIDDDVRLSHDELKQQLQAALETGKGRETWKGVIDKIAAFGPKRIGPNLLIDATKEGGCLSKVFGANSTNNSLGADDSLNASHLSDKITYGFQLATNQGPLCHEPVRGIAVIIEDIQIEPPEDETSARDRLGRLTGEVIKTVQQSIRQGFLDWSPRLMLAMYSCEIQASTEVLGRVYDVLTRRRGRVNAEAMKEGTPFFTISSVLPLIFTGFEILDEDPFWVPFTVDDLEDLGELGDKENVAKRYMDGVRRKKGLLVEGRGERRGAEKQKTLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9A7</accession>
    <name>A0ABR1X9A7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hsp90 chaperone protein kinase-targeting subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_002468</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674079.1">
        <property type="nucleotide sequence ID" value="XM_066806783.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039843"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.610">
        <property type="entry name" value="Cdc37, Hsp90 binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004918">
        <property type="entry name" value="Cdc37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013873">
        <property type="entry name" value="Cdc37_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013874">
        <property type="entry name" value="Cdc37_Hsp90-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038189">
        <property type="entry name" value="Cdc37_Hsp90-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013855">
        <property type="entry name" value="Cdc37_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800">
        <property type="entry name" value="CDC37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800:SF4">
        <property type="entry name" value="HSP90 CO-CHAPERONE CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08564">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08565">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03234">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01069">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01070">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01071">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101391">
        <property type="entry name" value="Hsp90 co-chaperone CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc37 N-terminal" evidence="10">
        <location>
            <begin position="2"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 Hsp90 binding" evidence="9">
        <location>
            <begin position="193"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 C-terminal" evidence="8">
        <location>
            <begin position="368"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="183"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="146"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8092107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="466" mass="52163" checksum="9F1EC6913CF0AFC8" modified="2025-10-08" version="1">MPVDYSKWDALELSDDSDVEVHPNVDKRSFIRAKQNQIHQERQERKLHIEVLKYERVVNDGLMKRISSLLDALKSHAAEAETRNPAEVAFQAVMESAGSAGDDKPPKRPEGVHGSEEEMPTYTKMMATLLDQVNKALDEKKPENRYNAMVEEVGEHLKKVQDLQKELLQKMAELEKMDQGKITSDSYHTGFDSSHVSKSQPGDKATSSKPELLNPNFDINKPADSKAVATTSDPDDDEEVQASLDGKRFANIKSNDYRESNNFIAAHPQILSEKEQDGILVMAFDAQLEGKGDFARNCDGVPMFFKRITTKGHQAQDVFYKDVSETYARIQSRCKEINAERAQEAASGNAGVEQIQLHAVEPGTVINIRIPPENSEDESEKQGRAIFEKFAPDMKKALETGSLDKVNEVLGRMKVDEAEELVGLLSEANILSLEEEIIDATTEDGQKHLKDMEERAALESYTDDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9U6</accession>
    <name>A0ABR1X9U6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000032</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674120.1">
        <property type="nucleotide sequence ID" value="XM_066804347.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037407"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF48">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G06730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="28"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="193"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8093347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="552" mass="59621" checksum="0032C43E40A8F394" modified="2025-10-08" version="1">MATDVNVPSGRDKDVWRQLRANPYILGLSAFASLGGFLFGYDQGVVSGVLTMENFAAHFPRVYLDAGYKGWFVSTLLLLAWLGSLVNGPVSDKLGRKGSMLLAVVVFTLGAALQAGGSNIETIFAGRAVAGFAVGMLTMVVPQYMSEVSTPTVRGTLVVLQQLSITLGILVSYWLEYGTQYIGGHRCAPDIPYSGGTPQNAPSIRSATSAPRAAQASPRRRGASPSRCRSSRPWEDKALKALAQLRRCHPDSEGLRHEFLAIKAEVLFDEAIARDRHLGKSGVLLYVAQYADLVSTWPSFKRLAIGCCIMFFQQFIGCNAIIYYAPQIFSQLGLSGGTTGLLATGVYGIVNTLSTLPALFLIDKVGRRPLLMCGAAGTCLSLVIVGGILGGYGDTLPAHPAAGWVGVAFVYIYDINFSYSFAPIGWVLPSETFNLGNRSKAMAVTTSTTWMCNFVIGLVTPDMLDRLGWGTYIFFAAFALIALVFTYFFIPETRGKSLEDMDGVFGDTAAREEKARLFGIAARVGLVDDRVPEEKEKIEAARVGALEVERRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA92</accession>
    <name>A0ABR1XA92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674409.1">
        <property type="nucleotide sequence ID" value="XM_066804636.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037696"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="192" mass="20570" checksum="C75DE88FC1CFC55C" modified="2025-10-08" version="1">MTTSRHRLPTPDPAGASALGHAASPPPAPIPGLQPQVYNGGGKGTIEIVMDDDDNNNNYTTNAAPSVLPASDADVPIIAPPQTRHARSQSVTENKDNSIAGRLSRATERMRSASRGRTNSALGQRTKSPEQTSPYESVLPPVSYKGPTPNNNDANNGQPQQHSMIERHPREVRATYHTRQNSGTGLSQSEMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAA5</accession>
    <name>A0ABR1XAA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450 52A12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000213</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674301.1">
        <property type="nucleotide sequence ID" value="XM_066804528.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037588"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002974">
        <property type="entry name" value="Cyt_P450_E_CYP52_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF17">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01239">
        <property type="entry name" value="EP450IICYP52"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8093528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="551" mass="61759" checksum="62D07A408FB9465B" modified="2025-10-08" version="1">MGFSNTTEAPMGTSRQLLLGLLCALLLIWAAKRTNLYLSRRRFKQAHNCRPVQRRFPNRDPILGLDAVYSQIQRAKAGTMLEWLHWRNSTYGPTFAARMGLRFPGWLGGGADAFVTTDPENIKTVLATRFKDYGHGDTRTGSFGPLLGRGIFVVDGARWHESRALLRPNFAREQIADLEALERHLSLFFQLLPRSGDVTVDLQTLFFRLTIDTASEFLFGTSVHSLRALQESGGLVVGANGEAAASASDSAFAEAMNDAQADILMRARLSWMYHLRPHPRGDAAIKFAHAYVDRFVEEAVRRREAMDLEKGGGSSSSTSTTTGTDGEKYVFLHELAKATKDRKVIRDELLNILLAGRDTTASFLSNLFFVLARRPDVWAKLKADVAGLEGRPPTYETLKNLKYVKYCLNESLRTHPVVPLNNKQALQDTVLPRGGGSDGQSPLFVPKGTIVAWTIYTLHRRREFYGDDAEEFRPERWEHLRPSWEYLPFNGGPRICVGQQYALTEAAYVTTRLVQEFERIENRDPGPWVESVGLTICSRNGVKVGLYRASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAD6</accession>
    <name>A0ABR1XAD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein-vacuolar targeting protein Atg18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000296</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674384.1">
        <property type="nucleotide sequence ID" value="XM_066804611.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037671"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="285"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="456" mass="49922" checksum="D4A2906E683DB9D4" modified="2025-10-08" version="1">MPDTALNFVTFNQDDSCLAVGTSKGFRIFHTDPFNKIFSSDDGDITIIEMLFSTSLVAIILSPRHLIIQNTKRASIICELTFPSAVLAVRLNRKRLSVVLEDEIYLYDISNMSLLTNIATSPNPNKIVALSPSSENCYLAYPLPKPREDTPDKRPSHAPPASLYAPVTTGDVLIYDTLTLKAVNVIEAHRSPLSFIEMNSDGTMLATASETGTIIRVFSVPKGHKLFQFRRGTYPSTIYSMSFNMASSLLCVSSTTDTVHIFRLQQPQQNQNSILASDAAAATGSRADRWSRSRSYDSGNDSPQQHDRFSPSDAAEARQPTQATNTTNNSHRRQSGSFSSILRRSSQIMGRSVAGVVGNYLPQTVTEMWEPMRDFAYIKLPKSSIATSKQGGGAPGQQLRSVVAMSSTSPQVMVVTNDGGFYVYNIDMEQGGEGYLVKQYSVLGGDDKLDSSSYGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB52</accession>
    <name>A0ABR1XB52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxylesterase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674596.1">
        <property type="nucleotide sequence ID" value="XM_066804823.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037883"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="616"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="716" mass="78806" checksum="2AAB6E85862F405B" modified="2025-10-08" version="1">MVSIQRPAMAPIALTGGRFDIFNDSSTDDDTSTSTVEGANVGPLGQSLISPLRPLSVSDAQNRQFKSPTRVESLAAELKRLHLGNSPELYHYKGRPIYQAKLKGQPCANLTRPPIRRDTFERLETVPEVEQRDPPESEAASVSAGTQHYIELPAHQFAKHPLALSARKLISVEEQVAKHRQGNFEWVLTVKVPVNPGSQDESDKTDSSKHSSVQTLLFGCNLLPSTGQSEKVESGKEIHQHTFTLLVTPLEGDQEPTVATPQKESHSPIAMAVGARPAVQGTPAKAVQHVPEVRIEEVSPPSDSKRGRASVTSVRVTSNSPPRIEDSVAALDQLEDELEAFDQAAHFEKIVSPISAKSPTSPMQSLSAAAHHTPGSASKVDRSSPRPVSSATYRLKSAEPERSPRTRRSASMIYLDSPKLKEEEKPLVQATPKKSTNKGLASLQPPKPLTKSNKAPTLPTFELPGEAVARRLKEKREARLSMKATAEQASVPAPSSVRRTKSARAPTVPKFELPGEAISRRKREEREARLKAQEEEERKRREFKARPIRSGTMPASIPRETITSRARQKGALAENVGKSTTTSPNKRASLVGGSLREPLSHVNNQSQPRGRHLTSEESTASSQARRATSSSTNSLGSKRGSVSIEEVQQQRLRGKDIYQRDNSYAQDREKERREREAMARLAREQAAEQSRLRSREWAEKQKRKRMTVGSVRDLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBB3</accession>
    <name>A0ABR1XBB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674656.1">
        <property type="nucleotide sequence ID" value="XM_066804883.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037943"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="200" mass="23386" checksum="A044BAADC287E5DF" modified="2025-10-08" version="1">MPGPVPQTTPSSPLFLLPSELRHRIWEYYLSFTHADFVDSMRPIHAPLVHHDAVLRIHRPGSRNERRIGFAVHGNLRFERLRRLVLVVELDYPYWNAWLDFFGAVLARAPGLEHLTVDWAPRKTTAAVAGYSFHRAGAWEYRRDEKKEGAFLNMLVGLAGLQNLSFYGRIPELWIKRLQQDTTLSVKCYSYRWWREPGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC52</accession>
    <name>A0ABR1XC52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">CAP-Gly domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_000942</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cell cortex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dynactin 150 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675030.1">
        <property type="nucleotide sequence ID" value="XM_066805257.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038317"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022157">
        <property type="entry name" value="Dynactin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF6">
        <property type="entry name" value="DYNACTIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12455">
        <property type="entry name" value="Dynactin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="10 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0243">Dynein</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="15">
        <location>
            <begin position="24"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="74"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="144"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1128"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1160"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="196"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="293"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8094257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1354" mass="150155" checksum="E85FB35968895C5D" modified="2025-10-08" version="1">MSGIKVGQIIELTDGRKATIRFVGQTHFASGDWVGVELDDDGGKNDGSVQGERYFDCEMGRGMFVRPTTIAVIQQPAPPPPSQRPKPAQRPNSMTAAPGARRPSVPDPQMTRRISLNAPSPSPVNRTRRPSSLVRVLAHKVTDETAWHKPHRERRDLANRHPSNARVSSVGTRPARGASGGSSRTSMAPPALPPLRSTRQASTSSTSSATGRGGVARTQSGRSSTATRGGRGGVSRPAGGRVTSGESLSGNEAGFGKGSDIGSPLKSDGEQGISPVQSRTQALEKLTGPAGSKASTPGTTTPASRTASGTARPAANNALTRENEDLKTKLKVLERKRLEDKEKLKELENIQEQHDKFVSINKKIEGKFQTTAQENSSLRKQLKEAEDRLGSIETLQAEHDSILELATLDREMAQEEAEVFKAELDALKLKAEELELDNEILRDEKAEYEKGTSAEDRQSTNWMQLERQNERLKEALIRFRDLKEEEDEKSKELLKSLQRDLTDFEAIREQYDIAKEKLVEAEMRVEDLKEQLDNADAAEEMIEKLSSDLFTQGEHVKELNATIEELEELREINDELEANHVQNEKEMQKEMDFKDTVIAEQARRMGQQDDNIEDMEYTLSRFRELVMSLQTDLEDMRASHAVNEVESEQLNSKSRQMMDLNLKLQISAAKTQVKTIDLELQKMDAQEAQQHLQIVKLFLPETYDADKNSVLALLRFRRLAFKANLLHGFIKDRVGGQAHPGHEDDIFAGCDALDKLVWVSSMCDRFVNAISHCTLEEFAKYDGALFELEPVERALNGWIDGLRRDELKEKQCASELSRTIALMTHLGEVHISDGLESFADNVQMRTVMMQSHLESAAAAFAVVKDLVQRVVPANGEDDELAQHFSRKVEAVVSQTRSAKVIVGKAVRALEDLKARHLSLTTETGEAFEQCESATQELSDMSRKIGSDLHALTSEEGRTEPLTYSDISTTVHRTVQTTYSASETDLFSSYLSKLRTLTSQIADLAAVCADLSQTQEFDRSQEPWIVRAQELKALKTVPVDAEEELRQLKESYNDLRRAVAVRDENLSTSNLRIETLEARMRDANAKAARMTELEAQILDAQASMSKLKEDIEKQDRELKTLEGDRDKWKKVAGDSQAFGTETGSASGGAGGPNNKAGQERAVATAREMDVLRNEIASLQAAVRYLREDNRRARAADQLHQHNWLAEPLLKNKPSPAEQRRELVAAESRDVLAELLKMAGSAAVYDLKTLPAGRLAAWRPAVASPQYHAARRAEDWASWKGWRDDVLDKARTVAAVEKSTAAGAAAREEREIKRRAAARLRIRMPGADGKMVPGAGGEVRIAGSQEWEGVLGKVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCQ5</accession>
    <name>A0ABR1XCQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone chaperone domain CHZ-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_001152</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a heterotrimer with H2A.Z-H2B, stabilizing the association of the histone dimer. Also, with a lower affinity, forms a heterotrimer with H2A-H2B.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CHZ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675240.1">
        <property type="nucleotide sequence ID" value="XM_066805467.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038527"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019098">
        <property type="entry name" value="Histone_chaperone_domain_CHZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09649">
        <property type="entry name" value="CHZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01082">
        <property type="entry name" value="CHZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone chaperone" evidence="8">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="33"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="115" mass="12641" checksum="E83A582F56A633B9" modified="2025-10-08" version="1">MSSSNGATVPEQTNQAAQQQVEKGKGKAANAEEPVDQSMDEDSDDDEEVNAAEEDDDNMDEIDLSNIVEGGRRTRGKVIDWAKAAENVPTNEEDEDDDDDFEGEGEKEDDKMDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCW3</accession>
    <name>A0ABR1XCW3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kow domain-containing protein domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_001220</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675308.1">
        <property type="nucleotide sequence ID" value="XM_066805535.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038595"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_uL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22682">
        <property type="entry name" value="Ribosomal_uL24m-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="350"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="382" mass="43139" checksum="9970AA5719DDB53F" modified="2025-10-08" version="1">MQKILKRVATAERVVARRKAARDRLHFNKERKDEEYGLRNQGHIVARDIGRAKQAIKDDWNLGPLAPNSHTGEAAAQYGAISEVRYKNPTVLRNEQKEARCAWLGGYKNLNIVPGDRVVLLHGPDKGKIGRIQNINQDDASVVVEGLNKSNIKLPSAFTNENNPPVMNIELPIPISGIRLVHPVFDPKTGVTRDVIINQLVHRSIVHDRLTGKVEWTRLVPGLNISIPWPKEEEKEVADHKVDTLRIDVEARTFVPTLLRPPMPETIIDELRNKYSKFRTRHEPEYLARLEEQEQAKKDRVYLMDSMRSPLQELHRAERERKKKKGKPRLTVEMLEEIGKVIAKNRQRTLEAAGVSDAAVAPSPQTSAPLPSSTESTAPPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD59</accession>
    <name>A0ABR1XD59_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TTC36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675271.1">
        <property type="nucleotide sequence ID" value="XM_066805498.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038558"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038906">
        <property type="entry name" value="TTC36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405">
        <property type="entry name" value="CDNA SEQUENCE BC021608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="239" mass="26406" checksum="CD5F8675F97BF320" modified="2025-10-08" version="1">MAVLIDSTLPKDPNIHQPAIYERVSQRERDIVVAMQQLEMQLAGFKTTTSVSDPTEQYKTCVAQLGQLIAEHSRYASARNNRAQALRRLYGDRMFLHGDDPTALAQGAAPSEKQEAAAMAFSDLDEAVKLLTPKSLFSSISPQASKTLALSHTQRAALYHMTAKGLSDGRNLHIHEDRKEIGWTKMDFEEAASRDFALGGRYGNEIAKRLAVATNPTAKLCGQIVREAMKKEYGPAFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDB3</accession>
    <name>A0ABR1XDB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CBF1-interacting co-repressor CIR N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675448.1">
        <property type="nucleotide sequence ID" value="XM_066805675.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038735"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039875">
        <property type="entry name" value="LENG1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22093">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER LRC MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22093:SF0">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="420" mass="48358" checksum="8EFF54B9A8A0F8FE" modified="2025-10-08" version="1">MPLHLLGKKSWNVYNTANIARVRADEEAARAREEAEEQKQQEQDAERRLAILRGEEPPPLPPTPDQPSSSGRRRRDDDEPWRGMGGGEKRKRKRAGEDDTDFEMRLARSRTEGSGGSASSSAVAAIATEHPYSESSSLVVKHKSSDAPLTDAAGHIDLFAPDPRQQKEEKKHQHKEKNPEAEAEAARKQRSFEDQYTMRFSNAAGFRTELSKTASGPWYATASSAGATTNDKRGEEPTPPVGKDVWGNEEPRRHEREAARIVSSDPLAMMKRGAAQVRQVEQERRAANAERDKASRQLRREEEERRRERKRRHRRHREEGGDDEANPNTSTRTESRHSEHRHRHRHRDTAADSERSRDRHGSRRGDDRDTERSSSRRQHRHESGEGSERRRHRSSLRDEKRSSRADDERPKKRQHRESRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDH3</accession>
    <name>A0ABR1XDH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rab GTPase ypt31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675508.1">
        <property type="nucleotide sequence ID" value="XM_066805735.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038795"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="212" mass="23370" checksum="9DA279BE80DF3202" modified="2025-10-08" version="1">MANDEYDFLFKVVLIGDSGVGKSNLLSRFTRNEFNLDSKSTIGVEFATRSIQVDSKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDISKHQTYENVTRWLKELRDHADANIVIMLVGNKSDLRHLRAVPTEEAKQFASDNHLSFIETSALDASNVELAFQNILTEIYRIVSSKALDNDSAGGPTINAGQKLEISKPADGDSANAGKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDU9</accession>
    <name>A0ABR1XDU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001523</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675611.1">
        <property type="nucleotide sequence ID" value="XM_066805838.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038898"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11380">
        <property type="entry name" value="Ribosomal_S8e_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.168.20">
        <property type="entry name" value="Ribosomal protein S8e, subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_eS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042563">
        <property type="entry name" value="Ribosomal_protein_eS8_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="202" mass="22933" checksum="5DDD566202F1DE90" modified="2025-10-08" version="1">MGISRDSRHKRNATGAKRAYYRKKRAFEAGRQEANTRIGAKRIHTVRTRGGNHKYRALRLDSGNFAWASEGCTRKTRVIVVAYHPSNNELVRTNTLTKSAVVQIDAAPFRQWYEAHYGQSLGRRRQQKQGKEEEAVKKSNAVEKKQAARFAAQGKVEPALEKQFEAGRVFAVIASRPGQSGRCDGYILEGEELAFYQRKLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE47</accession>
    <name>A0ABR1XE47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675735.1">
        <property type="nucleotide sequence ID" value="XM_066805962.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039022"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="769"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="770"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="812" mass="90874" checksum="3D83B8B64DF3AA2B" modified="2025-10-08" version="1">MVHDFPGQYSNIVLRSRMQLAVIKTIRGQYKNAIADFVILNEECQSTIDSKDSPISAEISYNYAVVLTRVGNFNDAITKLRGIDASSQIGEASYLQVNCSRLLGLANAYLGHFSQASRYIDRAKAKMEKVKEDCNQSRPASPETVPCATSIREGGTKAPRMSHLEAAVRLSQAQILLMQGKAQDGMSIVGPLLVDTEKSFGTSHLLTLETRFILCRLLTETGQLGQAKVKCVETIDLMAEYLDQDHPLILKATSALVGLHRLDSCPSEAFTVSENLAYKARELLGTDNRQTLRYEFQVAALNLWMGNHVDGLKQLEDAALTSSDRWGDDSPWTLSCVIEKSIALSLSGRSGECKKNLEDVLRIQCRLFELAIDDYDGDDLISRLLECLAPKPNQSKDFVEVHPSLLYALGAWAKNELTRSDAQRDRVIQAQRAILQHRKRSPSFGPSHYATLQAGLDLANTLRVDPDLKNSHEAESHYSEVISSGIALQGDLIVLLAEQGKYLSKIMHPGKDLEEDKDLEEEKTSEEETERFLDIPKLISHRLGSRHPDTLQAMLTALAPTFCLDEGRAVEMSVKLHQRLHDPRVRPQRPVECIKIEEKLGLIHYRLKNRAEAAKIFAALAESLRNGEGALLSSFDEGQEIKIRLDQETSRIVGEVLNQQWQEAEQSRKNHRFSDAVESLRLFSDLFKSVHGEYEEVSEKVSVTLAVALWEAGQHITSEFVPGFTKQTASRQQKEAVDILKSVISRMGHEDGVRDQLKEELDGWKEALATSSTHEPPSPSHSSIVESVRHRISVDECRDINKENEYEPNSVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT40</accession>
    <name>A0ABR1UT40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fcf2 pre-rRNA processing C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_015230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660429.1">
        <property type="nucleotide sequence ID" value="XM_066819544.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052604"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="4">
        <location>
            <begin position="58"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="129"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8061009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="166" mass="18696" checksum="DAF4A53AE567A0E2" modified="2025-10-08" version="1">MAETAASLTEDQIEQLLQEAEARLAAKASAQNATSLTKPAKLDVAKPSSSTQLAKAAPAAEEALKRDLQLLKMRDVLDSKRHYKKDNSRGIPEYSHVGTMIEGRTEYFTNRVTKKDKKRTLLESVMDQENSTKRFKSKYGQIQEAKTSGKKGHYKKMMQKRYGSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTS7</accession>
    <name>A0ABR1UTS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain- general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660933.1">
        <property type="nucleotide sequence ID" value="XM_066818745.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051805"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF49">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="511" mass="55393" checksum="CB729FADBA3F8970" modified="2025-10-08" version="1">MAMEKKLSDDAGYGCPVEDVRTLSANPQVDPAAEKALRRKQDMRIIPLSAGIYFLCYLDRSNIGNAKVLNASTHHDLLSETGMTNYQYTIALMMLHNLAVSSDSHRTTGGDDYIMQIRFLVAYGVFEVPSNILLKKLRPSRWIAFLMFAWGALTIGLGGVHSYAAVTVVRFLLGVFEAGLFPGLVYYLTFWYKTEERSVRVAFILASATLAGAFGGAIAYGVGHMNQASGLSAWRWLFIIEGAPSCASALFVFFFLPDYPEGAKWLSEEERAIAVQRLSVEGSKGHHNAMTWPDAKETLCDWRLWGHYLVYFGISTPFSSLSLFTPSITAGLGFKDLEAQLMTVPPYAVAYVVQILTSYSADHFNARGLHSAVLATIGAVGFLASAVLPADAYSARYGCLIVAASGAFSCIPPLLGWLSSNIFATASVGLAIALNIGLGGAPGQIVGVFIYKPEEAKTGYPTGHWVNAALLLMVAVGCVMLRLYYGWRNRKLLKAGGAGAEAGDAVRLFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUR4</accession>
    <name>A0ABR1UUR4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dehydrogenase reductase SDR member 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014754</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661256.1">
        <property type="nucleotide sequence ID" value="XM_066819068.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052128"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="347" mass="37122" checksum="9D9A4E3CCEEA3331" modified="2025-10-08" version="1">MAQLMEMLRVTLFGSRNDAPGGKGAPSFDPSRDIPSLAGKVVLVTGAAGDLGRTTAVQLARYGKPARIYVADLPRSSSNEEGLLRRITREAYGTDDAKAVPESGKAAGDDNATHTEFRFLGLDLGSLKSVRACAAHFIAREERLDILILNAGIIRVAPGTTSDGYEAHFGINYLGHALLARLLVPTLVRTAEQQSDTRVVVVSSEGHSVAPKGGVQFDALKGTCAEMSYGQRYGQSKVALIGLAKQLGRRYPQLKVAAVHPGRILTGMAESLRKESLLVRITAPIAPLVCVPVAAGIKNHLWAATSPDVVSGKYYEPVGIPDKESAVAKDDGLIERLWEWTEKELSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUR9</accession>
    <name>A0ABR1UUR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661236.1">
        <property type="nucleotide sequence ID" value="XM_066819048.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052108"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="549" mass="61243" checksum="3E91CD2B2FF3678C" modified="2025-10-08" version="1">MFADVRKNAVDRNDWDTIIEWPEQSNQFWVLFCEEHRIHFKQKADNAAAKHLAGSLHRLPTRDRRPAIVQLGYYIPDCTDQRRESHNAEVNAKYAAGYIPRNEHKREARVKDLPAPAPDRSPRKPNQPSAKSASSIITHPKTSHVYYAKYEGQHWAVVILGWDKLPEGCRHSTLAASELIKHDPPRCYNFEGYQRIIGWMSNYVDGGKSVEKREFPVMYFDEEKNYGWVPAKDLSKLDLDRANAPKRKGYPEGSYNDARDWVAQRCGYKTWEKLSAERKGLRVRDSAGPQPKPPDTIRSAGPQYRAPQSRDNSVSSFSNIGDVISEPEHDTNPAEKENTPKINDSVHIFSFEETLERLSANPDAFQNSLVSDIKGRDKPRSRPVSSARSTNSAPGMTANPAPEPAMETAQNAAPPAADRPASAAPVLAAPVLAPPVIIPPVSAPSPQMPTPQTPTPQAQVATIGGNQGPLVGTFEISSYERLISEGGELRSQLVWQRGSRSEPCVRLVISADRRTALVQGGPFELTINPQECLRVRLKTPLFGGRWPYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UW60</accession>
    <name>A0ABR1UW60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014999</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661501.1">
        <property type="nucleotide sequence ID" value="XM_066819313.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052373"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="15131" checksum="0C439D1E9D038E0D" modified="2025-10-08" version="1">MTSRTGIFTSAVSVETDLVTTTDINGQKSGLGSGAIAGIVVGAVVGVAILAALSWLIFRHRRKARGRPSSSARQTQEINSHRGPDDIPEPEPQLDQLELYRKEDRYELGEPDRIPQQRQEQYQKPELDASTSEVLHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWW6</accession>
    <name>A0ABR1UWW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014395</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660897.1">
        <property type="nucleotide sequence ID" value="XM_066818709.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051769"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF24">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="44"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="500" mass="54563" checksum="5B3E14F69324C6C5" modified="2025-10-08" version="1">MEEARREAAASASTPLLVSSSSAPAPSLDHFAPGDPENPRNWPSWKKWLTVAVITPIDLSVSWGASGFSPAASSFRADFGISETVAVLGLSLYILGLAFGPMSLAPLSEFFGRSVIYKGSYAVFLVLLAGSALSHSLVGFMVLRFFSGFFAAVTIANFGGSIADMWQHDETGAAMSIYLWAATCGSPSGFFAMSFVAEYRGWREVFWALLGTCGGLWLIMVLVLDETRHTTILRKRARDVAKKQRKDGAAGSTTTATPDALKRRSADELFRVALTRPFRFLFTEAIVSLNALYNGYLYGLSFLFNIAFNLVFGAEGHGFGKIGVGCAFLGIALGISIGPITNIWQERYYQRQLLRSGGVAVPEARLHLATHAAVMFPLSMFFFAWTTYATTPAIIPVIASAFWGWSFYTLILMTFQYTEDAYRVYSASALAGIGLIRNLFGAAFPLFGRKLFTSLGYQWGASLLALLAVVLIPIPFVLVRYGPTIRKKSPWASQHLDNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1G1</accession>
    <name>A0ABR1V1G1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661780.1">
        <property type="nucleotide sequence ID" value="XM_066816088.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049148"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="9"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="328" mass="38224" checksum="E3EEDD5564E179EC" modified="2025-10-08" version="1">MAILDEIPGLEVTVQIDGYNVREYTDPYDVNRRRSRDACPKVVKYIESKTGANFAVCFLKEPDFQELSHHIAFRVHVDSVEAGFFHEPNNFNYREWGVKVDGGTWKNERGVTSYKFRFADFSILPNDDFSLEEIEDHKNEASRIGTIKVSVYDMQDAIFVEEDGAQDRGRGRNTSSADEALTRQDYFAEKAVKGDRALHHSIDFSHRRERLTPRVQYHGGLVRRSVWADPQKRPFAEFEFRYRSLEGLMQEAIVSRTSHMDDEEVREYAQNLERDNARLQAQTNSNGKRSAPDDDSFQANKRTRMDIDPVVIDLTQDDDEEEEDDYWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1M9</accession>
    <name>A0ABR1V1M9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011845</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661852.1">
        <property type="nucleotide sequence ID" value="XM_066816160.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049220"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF30">
        <property type="entry name" value="DUF636 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03180)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="14467" checksum="EA78BCE4B5EA3E82" modified="2025-10-08" version="1">MSLSGSCMCGAIKYESSNEPKVTALCHCTDCQKWTGGAFTSNAVVPEDGFKVVKGEPKTYDVTGASGKNNRHFFCGTCGSSLYTKLDVMPGVIIIKAGGLDNGNADLGGKVDVEFYCKDRVSYLSDQSGAKQEPAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2L6</accession>
    <name>A0ABR1V2L6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661936.1">
        <property type="nucleotide sequence ID" value="XM_066816244.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049304"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42024">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42024:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="408" mass="45300" checksum="4D2E2C4214145534" modified="2025-10-08" version="1">MTRAVAAEQDGASSAQPVKAGEVRHPPRASFDDRYDGPFSRRSLTSGRYLSLSLVGTDYIHTWEETTCEALDASQSDLDISAPGVAHLQDKNLVRGDASAAAASRPAPSATSQPALEPIPPPLNYTLRGRRSGIALFVFYTFLDSLVLPVGLYFLLWYGFGPGNPKYHPLSASTVLTIVTTAIGGASIYELLLRAWRLWKKNSDCRVIGARRWYFDWFEWWFVFAWILIIIEIAVAFLPDEPDKRLLAMPLSTVLFIFGTVSLSIDILHHLRVPAPVRMSSIPRGAQLRPGIYPLIEDICAVDGSGRTEFRRRLNRRYAASHVFRAMLRRLGLFWAVGADGCALATAALVFGLAADSDGLVDYAYTVGWVLPFVWAGPWALATVLYVKRELRKEKRLWAIEVASRGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V399</accession>
    <name>A0ABR1V399_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-xylulose reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662422.1">
        <property type="nucleotide sequence ID" value="XM_066816730.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049790"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF13">
        <property type="entry name" value="L-XYLULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="30904" checksum="3A3498B917FA9857" modified="2025-10-08" version="1">MNGGSFAHGGMPSVKSDLVMPLFSLKGRTAIVSGAGAGIGLSVARAFAEAGANVAIWYNSNKKALDEAAKIEADFGVKCKAYSVNVQSWEAVRDAVDEIVKEFNGRLDVFVANSGIAWEDGPFIDGPIDRMQTVLSVNIDGTFYCARAAALHWRRQKQEGTTTDGQKLDNFRHGSFIATASMSGHIANIPQAQTVYNASKAAIIHACKSFAVEWVGFARCNSVSPGYINTEITNFIPAETKNIWRDKIPMGREGEPEELKGAYLYLASDASSYATGIDLLVDGGYCAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3W3</accession>
    <name>A0ABR1V3W3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662635.1">
        <property type="nucleotide sequence ID" value="XM_066816943.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050003"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045043988" evidence="2">
        <location>
            <begin position="22"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="416" mass="47791" checksum="4C29645380091D98" modified="2025-10-08" version="1">MGSTLSMFWMVFAWSLMTSKSSPRPSSVYRPTVEALSVDDAKATIARDEAGNRVVQWFETEAINQQIKGNHPENRTLLQLISDILIGAIRLQKLESWIRTNTRPPKDVTDKRAIFIIKEWKGNLYAKMFHSLVWWHPDGAQDDAMDYFSNSYEYMLHDTLSVVPHIQAKTSISSIMKNPDLVCLDPRSFDRCLASLERHMFLTRDFSVRMQFDLAGIKMVHPFHPDPHPFLDFLGEVLSDPLHPWRFYAIQGAKRSLSNYYYFLCTRAEEILATRGRAQDAEWIFPAYDKLFGRDSDTFWGEDPLSPEARRQWSNNWRAKHYPGVSKPQVEGKGPLWGRDRRDSPHYRNAFDRSLSQGPDSGPPFSEASTKKLISTSDFLKTNLLAQFIRGPKEAVSPGPDLDHYRNGVISSDLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V445</accession>
    <name>A0ABR1V445_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcription factor SEF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012424</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662430.1">
        <property type="nucleotide sequence ID" value="XM_066816738.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049798"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF7">
        <property type="entry name" value="NMRA LIKE REDOX SENSOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="4"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="31014" checksum="50822584C20668CA" modified="2025-10-08" version="1">MSSTQTILVTGATGKQGGALIDHLLASPRASRFDIVAVTRDIQSSRAQKLSSRGDLTNPDAIFEAAGPVWGVYSVQVNSDAEESQGKALIDAAILHGAKHFVYSSGDRGGPERSETNPTNVKNFTANAGREKSAQGMTYTILRPVTFFENLSGDIHGKGFARMWEQLGQKKLQFVATQDIGWFAAQSFLNPEKHRNRAVTLVGDELTQPEADVIFKKVMGTSMPMSPCPIASAVKMVLKDTVGDMFKWFKAEGYGGDIESCRGVYPEMQSFEAWLVDNKGRWVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V474</accession>
    <name>A0ABR1V474_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662734.1">
        <property type="nucleotide sequence ID" value="XM_066817042.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050102"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="55"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="215" mass="23311" checksum="528E523303FAE698" modified="2025-10-08" version="1">MAKDSKATPKNWPPTLSYLMKPSYAAHVTKEQLNALRTRGPDLASEIPLSLPKGPSALVKITAITQPSHPAHGQAGLCATRNLAPGSLIIPYFGVVHSDLALPQHNREHEKSDYDLRIDRDAQLAVDAAKAGNEARFVNDYRGIRDRPNAEFRECWDLRLKEKSMAVFVLPAGKNAARKGEGGIAKGEEICVSYGKGFWGNRKDGDGVAAGDVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4I4</accession>
    <name>A0ABR1V4I4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662852.1">
        <property type="nucleotide sequence ID" value="XM_066817160.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050220"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="147" mass="16140" checksum="68A5A91C916AB319" modified="2025-10-08" version="1">MLNVRSYFSLFGDLAAVYTEVHILYLTEGLAIVDKMQTQGLLEDDANKKMKDKQATLNRWTQKALPGIKDLLDKRQKEVIDGLEGKTKAIAADIAFLHVTPPDETKKAIEAAKREAEAKAKKGLSEGGSYYKAKIMAPFPVSAAPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5C2</accession>
    <name>A0ABR1V5C2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase III Rpc4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_013133</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663139.1">
        <property type="nucleotide sequence ID" value="XM_066817447.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050507"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007811">
        <property type="entry name" value="RPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05132">
        <property type="entry name" value="RNA_pol_Rpc4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="280"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="523" mass="55832" checksum="47B0236429BDD690" modified="2025-10-08" version="1">MPPRGSRAGVRGGARGGRGGAAAASTPVATSDNGDNTGATDLPPTAPEDGSASGTTRRAAASQSATPAPSTTGGSKLRPKARRRNSGDRAQLEEQRAKDLAAKIKIEEREQRDADRRARRGGRGGRGGDSSRGGMVRRTVTGHGPFSAVPGDGVKYGGTSGGYGGYGKSGPGGSTFRGGEKPEGFPRYMDRRANDVRVNIDQLRDDAAPESSYGGSQRSSGSMPYSIPRVEHKKEDVKVATTAELEAEEQEDDEETYTDLRAEMLRNKDAELSAAKDEELWHAAPANPQEVKVKAEPGTELEDEMDIDNIPAKPEAPPSPELQKKPKAEELDAREMAKERKREKVMQDLETQFSIADTRALMEELNVSQPGDGEEGHERDGRLYLFQFPPILPPLSRVSENDDLVEVDSTPGNNKGAKANAKTAASTWPAEGGFIGKLNVRKSGKVELDWGGMPYELCLGTETGFLTTAIIVDEPENDAAGGQGKATGMGKVYNKFVAAPILGEEEDWNPDLEEYGLPDPSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6I4</accession>
    <name>A0ABR1V6I4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Telomere-associated protein Rif1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012315</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662321.1">
        <property type="nucleotide sequence ID" value="XM_066816629.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049689"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022031">
        <property type="entry name" value="Rif1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22928">
        <property type="entry name" value="TELOMERE-ASSOCIATED PROTEIN RIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22928:SF3">
        <property type="entry name" value="TELOMERE-ASSOCIATED PROTEIN RIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12231">
        <property type="entry name" value="Rif1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Telomere-associated protein Rif1 N-terminal" evidence="8">
        <location>
            <begin position="137"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="13"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1083"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1466"/>
            <end position="1752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1127"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1169"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1181"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1193"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1322"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1342"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1415"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1466"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1548"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1566"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1640"/>
            <end position="1654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1676"/>
            <end position="1714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1810" mass="201022" checksum="762EB96D063435F0" modified="2025-10-08" version="1">MVPQVIVPNALEALPARPPTPPREKNINSDLTSRRKHIFGSQSLHTPPSFSPESSDLSNPTSRRNRKKVGFTSQPEYCEAPAYGDHAKRQHPTPTYQIHPETIAPVLANPLDPSMGSDGSSRPVDIVKMLESTVQQLAGADRDLKVDAYMMLVRALKNSNSLPDRIALQDKMGLFMQFIQRDITAKTSEGSLDSSLVNHALMLLSTFMFYPAIASTLSNDFGVFIIDHCIRSFEDASAPKDVTRHLMQVVAYQDFSPKVMTADRVGRLVSSLHTIEDRVKGKSIIQSRLFIYRRLIKQSKMHMISHSDWLLDLFEDMLSNMKEIRGAAIALGLEASFTIAKEKQFSRRVMEILQMSVDETKYIELYVGRLRAMLKEKSDSTAVPQIWSVVILLMRCPVDRWEFFGPWLEIIQSCFNSSDFQTKLEANYAWNRLVYALQLNDQSFAKTIATICQPFLSQLKRRSTGKQSSELRKVVFGSICNLYYYAFKPNTSTAHLDTFWDACVRPLFQRMIVPEADKASGTLHDHTSQATLILTGLFDSSTPRLWKEDHVWVDPLVKPEDLPALDAKWVRHNASRVFGVVEQILSRAYFELARPESDTAKFWRALVGAVASAASKEVKVSTDTATFVAHSFTLLLKVWSRGIEKADDTDSKSTTFFEATSIYIGTMIDALGLLPFTERQLSMGNQNTFVPVATPSHRPTKGQGQTRTPLHHLFSILSTLPPNTVDGQDLATLIQRVLAPFLSTVSNKSSRAKVDLAQELMQLVPMETLIPFGPWLAISDTFSNSLDNSQASHSSSSSSGQPPIGHEYREIVRHLERGIRSTPNLPWEHWQFLFQDLFVRVAADVGEAGCAISIAEPIAKCAMEIITAQPDATLDPTLLKVGSELISNAKHPRDRQALEAARRRLWGTSAGGSRSVSHDPFDSLYRLVNHLLEVTYKHYDDAISMAICSLLENISGFLLRCNQELALKALVIIQNGIGAWIRDTDEIYNSRQSTTLSEAVKQLWSRVCNTFAQADSLEEIQLDTIEPLLCSAFESKHKHIVSTATAMWNSAFEQSNNIQYPDKLKAVLLSLRPYVDIVLPGLDDSSNEASGQPPSFIDSQEDDSASMKQPPRSSRNGTPQMKKPTSRRSTPGSVQLSLPAERNLSSTPGVTRAGSARKSMTPRLRHNDSQIQFAAIASSSPTHNNAESQVLTDRQREVRDRQRDNAALFPEIKSSVEQRRPTRLSTPKSHRRIEDYVSLTPTPRRGQAAIIYNDQEMTDDVPSSPPNPDELSKPQSSSSIILDDWPPSSPISESPSRNRQSASHHSRSIVPTSHESSKEALAEEEMLEPTSEDVDVQMGEGAAEEVTEEETEDADVEDETTMPDVEQDLSRIESSLPVAAETSATKDPATPTHPRAQKDQGTPRSDNDVYVDALSSPNDSPRNLRSQTRTKPQPDKAASQPVADCSFEASDVDERSMLRLVVELDSRKCDAPTKDGTELAEKTDQKKRSPAKECITVNTVSGQTRRRSTRNKARSEETPSVIASTPVEPDSSQASNDTTQKKRKRPQESSQEGPQESGSKKRRHRNDVDSDHEAVPDSQLLPVNDNKSLEPSEISGVKQPSDSSHASSEHDHEEVDTDVSSPAADAPVDDSEAIHLQIVQEASQSEGAETTANDSFEDNKDDEARTALADLADVTMLEDMEQEEGTEDEEEEMAEAEEDAEDEEDEESEEEDDASVASESSEVMRAATTEEPPLMSSEGSAESPEVIPSPTKSSMERIMTALRGGLVELSTAALSRDEVSRIEDMFYDIKRELYIAESRGRGLHSQPPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7G4</accession>
    <name>A0ABR1V7G4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013882</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663888.1">
        <property type="nucleotide sequence ID" value="XM_066818196.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051256"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039241">
        <property type="entry name" value="Rrp9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="207"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="249"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="294"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="428"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="168"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="553" mass="61728" checksum="EE03824EA2859495" modified="2025-10-08" version="1">MSSFFTIPGAQKKRKRAPTTENPKRDPMAPLPKAPESSESEDGGFDEPEDAQEGSDSENEGETAAEKRLRLASRYLENVKEQVEVGFNAEDVDREILLERRLREDVAEAKGKVYRTIAGELAPEKASHTLFRGNNLATTSVATCAPFAYTVHKDRTLVKWRLQDLPANQFPQTTKKKPKKQAPPRRQPDKVLSRQGDRAKAAKNKNYQGHTGEILCVAASEDGQYVVTGGSDRRLIIHDAKTLKPLRVFTHHRDAVTGLAFRRGTNQLYTASKDRTVKVWSLDDGPPFAYVETLYGHADEVVDIAALAQERCVTVGARDRTARLWKVVEESQLVFRGGGSEKKTKADHINPKSLALENTMDRVAMLDDELFVTGSQNGSISLWSISKKKPLFILPHAHGFEPPLRPEEASAEKIPDLKQVSPEQPRWITALRTLPYSDVILSGSWDGCVRLWRLSEDKRQIEPVGVLGQPSGVESEEGEVLVNGNHSDENEPWFVKGVTGYAWWLPWAKEHRLGRWKTVKGGKNGAVVFEIPRREKDVANGDDSSNKDVDMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7K5</accession>
    <name>A0ABR1V7K5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663921.1">
        <property type="nucleotide sequence ID" value="XM_066818229.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051289"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="210" mass="22355" checksum="C0F10039BB1C2352" modified="2025-10-08" version="1">MASTSASTSGSPVTASGPNVTVVPPPAAGQQQQAGFHVAPPAQAHMPMHYQQQTFQLTPQMEEGIKAAVAATNPGPPAPPRKKRSSWTMAKYFLRCATLFACVGMIIAEVIVAITQRAELDTAISVIWRSETTSRAEVTPPEHLTPTTTPPPPPPAQIVVHYVQNTCPKCGTQSWPQPGEELNEHLASKGDLQPQAIPLSQLQFLPRAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7N7</accession>
    <name>A0ABR1V7N7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone-lysine N-methyltransferase, H3 lysine-4 specific</fullName>
            <ecNumber evidence="3">2.1.1.354</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">SET domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">PG997_013944</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. Binds RNAs which might negatively affect its histone methyltransferase activity. COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60260"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.354"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60272"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60268"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="Rhea" id="RHEA-COMP:15543"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the Set1C/COMPASS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.354" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663950.1">
        <property type="nucleotide sequence ID" value="XM_066818258.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051318"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20072">
        <property type="entry name" value="SET_SET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024657">
        <property type="entry name" value="COMPASS_Set1_N-SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044570">
        <property type="entry name" value="Set1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017111">
        <property type="entry name" value="Set1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024636">
        <property type="entry name" value="SET_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11764">
        <property type="entry name" value="N-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11767">
        <property type="entry name" value="SET_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037104">
        <property type="entry name" value="Histone_H3-K4_mtfrase_Set1_fun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01291">
        <property type="entry name" value="N-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51572">
        <property type="entry name" value="SAM_MT43_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RRM" evidence="19">
        <location>
            <begin position="283"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="20">
        <location>
            <begin position="1130"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="21">
        <location>
            <begin position="1256"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="124"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="384"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="560"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="737"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="847"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="903"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="567"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="742"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="752"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="867"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="908"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="22">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK8067197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1272" mass="141724" checksum="D140C7E02693EB1F" modified="2025-10-08" version="1" fragment="single">YGSKRNRREFRPVFPCRPSRCQRKATERERAKSRASSDAADRDPRMSSSIPSTFGPRDGPAKSDLSISDAAHPLISTDDTESAQGDILNGVGSASSHASTTSSVFSANNQSASLNNFSSRASNSNLTPLTNAGSSPSSSHIPPSSQLNLQRNKQQTTSGASQLSEVTRTQDGTSASHTTTSTSSSSAHRHGIVDRIPARDPARQIKGIKRTHDPLTDKKLSSTDRKPQKPVYADLDPRLAKGSWLDYINVDFHLAKARLRQTPYNLKAYPYDSATSIGPGPPTQIVVSGFDPLVAFSKIAQGFSTYGEIAESSNKMHPETGAYLGFATFRYRDSKPGRRPPISAVDAARRAVKTMNGRRIESNQIKVDFDRDGKKSRLMLENVLKRGREEEQQRSAAIRSQRGTPAPQAAAAAAHRPRGSLDGLARPPPTAPRGPAAFRQPAMSTPEPHSSFAMPDKPKSSLIELQPISEKLRTEPYLFVSGANVPVMAATIAHMKKRLKSYLIEDIRADRSGYFVVFPNNTRGREEAYRCYRSANGSAFFNYTMAMELVNGTAPAATNYTAGHTRQRSEPERKAAPEPRIRSERDIRRRDEEAVMKEEKEQRAKDFDPVTEAVQIVRREMREHLIRHIRTKVAAPTLNTFLDPANHAAKRRKLNLPDPLEFMGPTVTIVDEDEPTPVSTPNSRADPIERRTARLDVTALPRIRKSKAAARRNDGFADPFGRKRAAPVRNAFRGLHHRLAPDSDDEASENEAETRDSMARDTEEPESRPRSRMSTDEDGFDDSMTEASFALNDGPIRTKKRKLDLQVEAAIKRQKKTDEELFGVTIGTLETDFPASDDVADVIIPDADADREQTPSTAQPPTEKGAKGKKKPAAPKTKKKTKKQLFEEREALKKQQQAEAYVEEALEQAEKEETVEPDDVPEKVALKPALKDDSEPVVRDERFSDAIVPAMALPAKFKLDIPSMMELPMDPKDGPDLTKLRKKFPVSEIGDPRLWIWKHNRVRELNAPAHKQDEPLVIEGYYVPNSTGCARTEGVKKILNSEKSKYLPHHLKIQKQREERQARAARNGKDPVASAAEAARLAAEKLLAKGNSRANRVNNRRFVADLNDQKRSLGQDSDVLRFNQLKKRKKPVKFARSAIHNWGLYTMENINKDDMIIEYVGEEVRQQIAEIRENRYLKSGIGSSYLFRIDDNTVIDATKKGGIARFINHSCMPNCTAKIIKVEGSKRIVIYALRDIAQNEELTYDYKFEREIGALDRIPCLCGTAACKGFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V853</accession>
    <name>A0ABR1V853_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664128.1">
        <property type="nucleotide sequence ID" value="XM_066818436.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051496"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045718770" description="Extracellular membrane protein CFEM domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="16093" checksum="7D1AF94DA59373B7" modified="2025-10-08" version="1">MRLSIAILALVAQAFALESLSQDVEDIPSCSHAALASAMRKEGCPTSDISSATFDCLCRHMTPILVDVQHAVSVDCTTMFATAIGKVCGEWQVNQYASTTASDLPAATSILGTELGAVAAATAGPASPGATTLKAAADTTARPMARYLGAAVAAVVMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V867</accession>
    <name>A0ABR1V867_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664157.1">
        <property type="nucleotide sequence ID" value="XM_066818465.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051525"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="319"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="441" mass="49563" checksum="92ADF17D867B939B" modified="2025-10-08" version="1">MPSTNDGSVVGSIESFCEEATSVVVAFEGRYERDAERDLDEDRHKLRMSFKASYSLPVVTFRFHVNVFGHDDSGKKEKTTLYFDVPLHHISSLEQTRHVDTAELDQDDLRYFPGGLTRVRFLLKRPGNLVQPVRGLTLKPASQRIFGAMTSLAAALDFDLLMPHTTLSKDQFRCLEQAVTSPISRHDLQEQHKERDWWLGALYGGVGGRLFNPDDSTDSECESTIATATPPAYRRSVEDAADDAVTESDDGDLDADSPPPYDQLDSEAGDPADTKAAGKQRRKRLRDSPDPDIRLYRRRVFSPPVAGASCLEKLESNPVALVLAKLEQVLKKAQDTEEENKSLRAELSAMRQRQDQLEGMVRRHLEVAEQQRQGQLDKRTQTLEVDAADLDTRVNALEERQAELEDRQGKTEDKCDAIEVEIADQVHCALRERLIGALETM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8X6</accession>
    <name>A0ABR1V8X6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663267.1">
        <property type="nucleotide sequence ID" value="XM_066817575.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050635"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.20">
        <property type="entry name" value="Insect antifreeze protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF31">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047442774" description="SGNH hydrolase-type esterase domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="355"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="549" mass="58756" checksum="EC00E4965CA73352" modified="2025-10-08" version="1">MTRLTQLVGLLAFSSSLLSPLVAAQVDGSRVIDTSVNSRQVDGSRVSDTTINSRQVDGSRILDTTINSRQVDGSRVIDTTVDSRQVDGSRVSDAAIDSRQVDGSRLPSDVVIERRQVDGSRIADVEINARQVDGSRVAEGESIGSRQVDGSRIVTEANVDARQVDGSRVSGESTIDSRQVDGSRIAVDDSLDARQVDGSRVTEGEGVNSRQVDGSRIAEADIDARQVDGSSITDGDNISARQVDGSRVGDSAVVNSRQVDGSRVIAEADINARQVDGSRVGDSEGVNSRQVDGSRVSDTAINSRQVDGSRVISDADVQARQVDGSRVVNGEGINARDSQVVEATNDFQLRIMPLGGSMTLGLQSEDSNGYRKTVHDRLFSDGWSVEMVGSRANGTMAENSHEGWPAYTVDQVHGKFSQAKGMKPNVVLLNAGTNDCLFNVDPAGASKRLTSLIDDIFVSIPGVTVIMSTLLPSRHDADCVADLSEQYRAVFASYEKQKRRVALADLEKELDFKYLSPDGVHPGDEGYVAIGGLFYDAVKKAQGQIQKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGM4</accession>
    <name>A0ABR1VGM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010596</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664201.1">
        <property type="nucleotide sequence ID" value="XM_066814911.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047971"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF3">
        <property type="entry name" value="C6 FINGER DOMAIN TRANSCRIPTION FACTOR DBAA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="94"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8070393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="615" mass="68876" checksum="85E88889ECDA2160" modified="2025-10-08" version="1">MTTINVASPTPTPPRHRRQSSQSQGAPRSSRQQPGLACEECRRRKLRCDRKTPSCKSCFETGVVCVMPATAPPRGPKRGHLRCLPALESRLKEQNETAWSHHSHTESEDGSYRDPASPPALSGHHRDYSSDSLNTVPMSIGMPATPSQSTATPPPTSITWASPMIDPSLMFMDDTMDGNYFSLQSHTPNFNEMAVPVGLHLTPLVCTDLDQLYFDRVHVFAPMIHKDRYRSWTKQIDKPKRQLCLQYAMWTMAASLSSQFQMVRDGLYSETRRLLDALELEPTEFGTLSLDYAQAWILIAIYEWTINDCNRFLMSAGRAFRSIQLLRLHELDCSPTPTPWTGDWVELESARRTFWVAFDFDCFTAIHNGLPLTFNEQEIRTRLPVPESQFLAGRSPVTMPFLDEIMASCDSARASPTCDFPTSPLVECIFAASLCGRNVTHKQRSLVEQCRGEVVTEDFCRRHQSLDALLTSRIKSLGAACGQDFSLLTDPSLIFAALVAHMNVLFLREVIDSMMLETEMSHALRTQQEQKAFLAAEQMGKLATAVSNLDRFQSHFFTAIPLSMAARFYMLHSVPEGDCSPHLQTICAILQNITGINSNLSNGFQLSSVPPLEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHV9</accession>
    <name>A0ABR1VHV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664593.1">
        <property type="nucleotide sequence ID" value="XM_066815303.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048363"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="288" mass="32810" checksum="C0175C466673AF57" modified="2025-10-08" version="1">MDDRDAGHASEVEKATSELFGHGRTQQPSQRGSKVARGTFTQYPESLRLQHHEESEPIPPLDFDKAIANAKAQDEDTWQAWATTVVEGKVQQQVDARKLSPDSVACGTYRAKVFDYLMRRSTWFAKTFDQNMSKHIEVKKVEFHAQILTTVLEGFSVPASTYGHLEGVLRKISDGIVKAKTNDSQQYWIMITKYNWQPITQSTQTGRSPKYMAHLIRVIQLQVSLQAREYTVAKSKYESVSFYLQYNQYQADFNAEIFANIRPQIDQKQIETGIELAQARTTVVSIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI05</accession>
    <name>A0ABR1VI05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apopolysialoglycoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664679.1">
        <property type="nucleotide sequence ID" value="XM_066815389.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048449"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="803"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="744"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="830" mass="86759" checksum="BE67255E94E25205" modified="2025-10-08" version="1">MAPNFRTNTQTRRGNRAGYVEHDDFEGLPVRQWRQEWVSVAPPPPAETTQKSDIWDVELPHGMPKDSQLLPQHTQELLRAARSGRLYKRPAPVEEEDADADAAPEKADKKDDDQSTKGFLIRAWKQIPRNSEGSTVSHLAKRRKNTVTLSSSLPAGLTSGPTVTKATVRRVDAAGNPYTQEVTLAEGQSVDGEIISTTVVPAPPANVNPDGTAAPTPVKRRPPPPKRKPKGPGRGRKKKLPLPASTRPEPSGAPGAVPTDGPKPENAGAGAIKKEGANDQHNEHKNQDTEMGEADDDDEGSDDGEEGEEGGDDEEGDAPDTANGTPAAHDKESSADQDMKNSPSVEPPVITAPPIDPDAMEISAPEESQSTTSAPSLPHPSHLMASRLEGSPLKNVLSITSPTEAAPAQLSHVSPPEIVSTTSEPTVAPPTETESDPIPAPVESVEQPLEQPVVSSEQPDIQQDVVTEPQPSADVHMMDVTMTTTDVAPEPDVTAEATTEAVTEAVSETVADTLPQLAPEAPPEPMPEAVPEPAPEAALEAASEIMPEGVSDTVLEAVAEAIPEAAPEVMPEATSEVASAAVASSGMEGIEMDSTAEIPRVAERTPKQQSPREASQAPENPQLDIDPLPSVPEPSIPAEPVSAAIPEQTQPDAEIQQQVSDHIVPIPEGQAEEPASSLPPLNPAQTLDLSGDPPATAPETGNEPASPDLLGSLEAVLDRHHSDSKEAPSNDQPSAEVAAEPESTVPSDLAPTSQPEPALPVEAPVEVPIEAVVEAPVEAAAEAAVEAAVEAPAPSIVEVVSEAPAALPEGETGVPQVEEKPAEQDPEATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIN6</accession>
    <name>A0ABR1VIN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664555.1">
        <property type="nucleotide sequence ID" value="XM_066815265.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048325"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="253" mass="28501" checksum="197BEA17C19FEAB3" modified="2025-10-08" version="1">MPGSYRITNLLYQGFASDMSWETRPEWDPQRNASICRKLLENGDMDKLHRSLRKCLKLPDNARLRSLKKPVIDEHFGLLYEYASHNVKECAKLDPVRFFAAVKEPFAWAGPIDPEHLWKFTYRALMARDNFLKNQAGAENSPGYSMVKYLDAYKRAFFLDLPPAPGQLAKPRGGHLHQHATGRDLPRHGALLSPELTCAGGQGDGTDRLVVVDPSRATSAGHVRRNNNKPVDSSDEDSEDDEEEKQKAADAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIW6</accession>
    <name>A0ABR1VIW6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664982.1">
        <property type="nucleotide sequence ID" value="XM_066815692.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048752"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="668"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="914"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="922"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="942"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="981"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1106" mass="119245" checksum="A5BA9F642A55D672" modified="2025-10-08" version="1">MEGSRENPNGAGGHHDDAASRKTQNVLRSMANDLGVQRLEDLAQDDDRLSRGDRMRATGAPAKPKPLANNDWQNAVQSNLFEDSDAREWQGLDSIADGRLHAERRDARARGGNGPLGLGMVQAAQSNGHHGAQNYFANPARGSQYDPRNPQRRGGARRLGRGSPTHHGSGGPTNSGRGGSTNSGRGGHHHGPDYGSGQVSRLGIVVPPGAQVFTFENSRSVAPTPQPAPPPSQPIQLRLGGPATLPSGRPAQPQPQRNEPTIFDAPHGTSTLNNNQKRSASQQEGSNPLFSRASVAGVATPFTLSSSQTNGSTNTPSHKRLKETLPHLRPASVRPEAIASGSASCAGVTEPPQDHPTQRYPRDSGKLPRSTPQSQPDVDILFESKVEIKSAQRDADGTIPDSGKVLLYMHPGYCGWMIWELQGNNSFITRDDVRAFFPAMPMGSSVIFRRRLPDEHKVAYTHNLVFPSMVAVQELQHLIEEGKERMNYINGPWFQQGPLKVERLGLVDVYTLLEINRTSGSTQSTVQPSTGYNQANSQAVQQATHGTTGAQSANHNRDHGDNTIPPHKRSVKNTAPVQTSETIEGNSLVASRSTQNGTSRTQENSASSLIDTTSPVNGNSLDRGVQASPMPPKLIEIEAEDKGKRPASEDLRDLTYKTSLLSTSAEPVGKQPFLEANGGASKPSLRSNPDVAKQVERIDANTPKHDTLDQQLFSRPEVASGTNYINAASSGENDASQNDNDHTDNQGTSSEANELGNEPEQDTGLVLAPTHNTIKVNDVKGKLPIRNLSSASKDLVMGMTRAKYVGMIDSVKGLWNACVQMDMFSERRLENATLLATWQAFYQNPAFRRFNGDDKLSTVAFVYDKVYRCLTDKRVTYSFYELTELCDRNYSSADDHLVTVLGEKEYKGYRRTTYSTPANAQSSMPSTPTSTPIAGRAVASPSPAPPKEPGRLTPPPDLSQPREQQVAVESTPAFVDTPDHSSSPITPAPSASSETNTLGQNADNTKMAIKQEDREPAIKVEAQLNASSSASQVPRIGTNWKSQTPAKQAEMVSVARPPTPSPLTPTPNSQVPGNRTGSQGPSSVFPHMRGMRQNLGSAGLSGSRWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VL71</accession>
    <name>A0ABR1VL71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664854.1">
        <property type="nucleotide sequence ID" value="XM_066815564.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048624"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="128" mass="14701" checksum="E3A32944CBFA9920" modified="2025-10-08" version="1">MASKAVVNEEDDTTSITARGAVISLSTYYWLTDDHGEDEYAGFEHYVTFNWVLQDRGCKSNVGELKGMVYERVQGKLEIQEKPAEWAAKPERTCNWGKQRNKKKCEEEKEACGWDTVTWLDMQVEARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VMZ2</accession>
    <name>A0ABR1VMZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665092.1">
        <property type="nucleotide sequence ID" value="XM_066815802.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048862"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="29752" checksum="CE8E5ED52E678079" modified="2025-10-08" version="1">MPTTLAEGRQTLAPEAGPANTGNLNPDDHVITTLPNGHIAVGSKGANGESLIVLDGSNTIIVPTALSTPLTLTTLGETFTFSPLPSAVGDHTYEPRTTTLPNGQIAVASKGPNGESILVLSSSNTITLPAATSTPVALTRMGETLVSPPQPLSDLGQYGTTTLPDGHVAVGSKGPNGESLIILDGSSTVTVPTSLSTPVTLTTLGETFTFSPPSTTSPEGGTDATAATMASYTPLVTTSSKPRGAKCRRVLSISRSLMLRQNLRALQSRELQPRALEPRALQPQLLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VN53</accession>
    <name>A0ABR1VN53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011547</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665152.1">
        <property type="nucleotide sequence ID" value="XM_066815862.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048922"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="3">
        <location>
            <begin position="317"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8071344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1032" mass="115751" checksum="BFD67C38C1FF2DA2" modified="2025-10-08" version="1">MHGILGLFRGSPGPGSALGETTGDASQDETSYGPLILSPGSATNQGVDIIFVHGLRGSRLGTWSQGDFCWPRELLAKEDGFETSRVIAWGYDSRVAEPTAYVTFELESLGPSFSSPIALGGLVVKEALIMAASYHSNGRFPDQAELYKSTRGVVFYGTPHRGSGKTALGGMVANFAQFSLLQPNTQLFNALRRDSHVLEKQRDEFATISRDMDVLCFAETKPTAIGMIVPPESAVYDGFRVQSASADGNHMEMVKITEHHARLKTLLEALKYDTVKPSDRTTDTNTCNWILKTPADYDSNGGHLPTIPSWLESHDGRIFWISGKAGCGKSTLMQHMSHILNMTSTLSLASVKKPPLVVYHSFYELGKPLQMTQEGLLRSSLSDMLRLALEAFQEASIPLIFLIDGLDEYRMPPCPSDGVDNDDEYDSDGALDTNDDDDKFSSERHERVTKGHREVAEFVQTLAERPGVRVCIASREMTIFKVHLHTMEDIKRVCRSRLEDPILQPLAEEIVKRANGIFLWVRLVLDSLITRWIDGTSYNELHRTVERMPPRLGGRNGLFMRMLHPSGGSNITHVFLVARGQNATNRSDAATDRDLLDTTRHKALLASRCGGLLETRPEKPTGTIIWEYDHIAVVHLTVADFLTRGYVARYLNKHCGDISTFDPYLALVDGAIRYIQLQPDIVQQWMRDGFAATAPLHVMMYAAFADMKGSDLDQHVALVDRFDQVLTKVPLMIPYLKFMSQDERLENAELWTSKGYPGPETRDEVPRLRIPTHYLWPPVRSFLDYATVCGLARYVDQRLRLLRPDHRKSEASRLLDLLLEPFYDAYRGVYCTFCDHRTARMLLSHGTAPSSRSWWILLETGYHTGSAESSDYRLRHLGPAPPPPYGRNAEARSPISSLDDLGPRLLLWDDPAESRAEIGRVVGRSHMWFQAWSAAFGVPSHLPPLTMDSWLDLVRGFVDNSSVDILVETWDFAEWDDEAGSFCVHERPIKAAEMINLCLQREFGATEGQAEWAQLMAEYGVKFVYERQPNDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTS8</accession>
    <name>A0ABR1VTS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DASH family cryptochrome</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009329</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665606.1">
        <property type="nucleotide sequence ID" value="XM_066813644.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046704"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014133">
        <property type="entry name" value="Cry_DASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02765">
        <property type="entry name" value="crypto_DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF22">
        <property type="entry name" value="CRYPTOCHROME DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0157">Chromophore</keyword>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="8">
        <location>
            <begin position="5"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="530"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="203"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="530"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="564"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8074666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="874" mass="95860" checksum="4A50B3AAEE3492F3" modified="2025-10-08" version="1">MSESNVLIYLVRRDLRVSDNPILHHLATTEGHGFTHMLPVCVVTPNHYEVSGFINDGSSSPFPEARSIVGGFWRCGPHRAKFVAESIWDLKNSFESLGSGLVIRVGQFSDTLKSLVGGLKAEGLNVGATWMVSQEGYDEKLEEDSVSAYCASEHIEFKSWVDEKYFIDDRDLNFENAQDLPDVFTTYRKSMEPLRERPRQAVPKPPQSSLPDFPPASSIAPQAAPFEIPTDLDAFREAMLKKVRDFIQFLPPFPEDAESAHPFSGGETNALVRLDDIIKNGVVLRYKTSRNGLVGTEFSTKLSAWLALGCITGRQVHWRMVDYEDGKDETFAEAEGYGKGENEGSKEVWQKLFYRSGFREDHSHKWKAPVKKEGTQEPSESDAAEDVDRTLQRIFDGTTGMGLIDATQRELLHTGYTSNRARQNVASFIAKHLNIDWRYGAEWYEMLLVDYDVSSNWANWQYVAGVGNDPRGEARIFNPVKQAFDYDKEGTYVRCWVPEEDWDRFNLTGLVMAEDPVKRIDFTVDGKPNKHVKRPFDRRRKDGRIRSATNTQVVTDRQPHQSENAANAPNGNNYGSQYGPQARHFPQFDPHAAQEVEGSGEVEEEVLVEAVVEEEAAMAVLQTEGFRGVVGGIEAMAVGNHSSTQMHTPNTGRLPGPEGRCHGVLRKGRQVDTLGHDEEGAGFDADPAVLGLDVAVDPKLAVALAAAVLIHGLGALLDDGPRPHRVKGVSHGGLLVVELEPGRDARAAGEAQDGAAAQRLVQDRRERAAVHDARPAGRAAAKVDDVDQLARGRVPEDALVGQALGAGEGARGDAALALLAVAATAVVVRGPGLPGRVRGELLHEGQPRGPLVDPRRHVQVLGACPVLGAGAGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV44</accession>
    <name>A0ABR1VV44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Proline iminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009782</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666059.1">
        <property type="nucleotide sequence ID" value="XM_066814097.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047157"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005945">
        <property type="entry name" value="Pro_imino_pep"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01250">
        <property type="entry name" value="pro_imino_pep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005539">
        <property type="entry name" value="Pept_S33_TRI_F1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="37"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="303" mass="34147" checksum="796064E348704C0C" modified="2025-10-08" version="1">MVYTQEGTADFKVAGIPEPCKTWYKVVGELDASKTPLVVVHGGPGACHDYLLPLTDLASSLPLVFYDQIGNGRSTHLPDKNGDEKFWSVELFKDELDNLIRHLGLQARPIDVYGHSWGGMLVAEWAATPSRAANLRRLIITSSLASMDLWRIGITALRDKLPQDIQDTLSRAEEKRDFESPEYEAAIEVFYKRHLSLKRPWPSREVQAALDWFAKDPTTYGTVPASYISGSLRDWTCIPLLDNINVPTLLINGSEDEAQDVAMQPFFDRIKKVKWVTLDGAAHFSHSDQRQKHMQHVEAFLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV61</accession>
    <name>A0ABR1VV61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009794</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666071.1">
        <property type="nucleotide sequence ID" value="XM_066814109.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047169"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF5">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="509" mass="59522" checksum="591C3246EE708DE7" modified="2025-10-08" version="1">MDSPIVTQLFRQLFRHRGCNSQRNLVALSSCIQHGHRVQQQKRSMAMRHTTTRGAKPSQRTNESDWQQRTELFSHDMTEEYKAFPTVTANELRTRTERPRRVKMLMRDFVEDSLYNPHYGYFSKQAVIFTPGKPFDFPALRDEPEFYTELGQRYTEFEDELDSKLPAPNDTRQLWHTPTEMFRPYYGEAIARYLMSNYIMTSYPYHDLIIYEMGAGRGTLMMNILDYIRSVEPSVYDRVKYKIIEISPALATIQNSQLLATAASRGHSDKVEIINRSVFDWEERVPSPCFFIALEVFDNFAHDVIRYDLNTEEPMQGMVLITENNDFYEFYEPVLDPVAARFLRVRHAATGGRYPVPYSNSKLIRKLKQQIPFAPNLSDPEYIPTRCMQFFDILEKYFPAHRLVTSDFHTLPDAIKGLNSPVVQTRYERRMVPVSTPLVHQGYFDILFPTDFRIIEAMYGVITGKLTRVFSHEDFMRSWAYVEDTEVQSGENPLLSWYKNASVMVTVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVL4</accession>
    <name>A0ABR1VVL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009949</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666226.1">
        <property type="nucleotide sequence ID" value="XM_066814264.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047324"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="14626" checksum="458170CAE2E2E6E7" modified="2025-10-08" version="1">METTFPQDRDHPGDSQPRTTLKQYMALAGALVISMIPVGFVLLHIALYVDEYIQIWERTRLQDEARPRLVQDEQAQNGGEWERGQDPDLERNLVGEGGSEEDNDWLYSGASETSHLLSAAFDPHSRDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW38</accession>
    <name>A0ABR1VW38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010112</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666389.1">
        <property type="nucleotide sequence ID" value="XM_066814427.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047487"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8075449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="178" mass="18926" checksum="A16B2BDAD1A9F0C2" modified="2025-10-08" version="1">MQLGWWNPFLMLSEALVCIGGGILSTIYPGISDGHWIGYQIFGGVGYALSTNLAHLGMQASLPKELVPLGASNLLTIISTSCAIFLAIGQALFQQRLIVHLSSVVEPDVVNKVISAGATNLGSVVEPSQLTSVIQEYSNAITDVFYIPAVSPVIAFFLLSGCAWISIKKKATSDKDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX90</accession>
    <name>A0ABR1VX90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666811.1">
        <property type="nucleotide sequence ID" value="XM_066814849.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047909"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF4">
        <property type="entry name" value="ESTERASE ALNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="280" mass="30711" checksum="A2A2C1B800363C20" modified="2025-10-08" version="1">MKFLCLPGAYGSAKNFGVQLGPFAKHVEDRGLANFTYTQGVHEVDPPAGWEHYFGARPVYRFIDCTSGDGGDAFEILRRVRHIPRGLTPEATLRLFKKEDDEVFDTSSAQEALDSIFKTIDEDPEVDALIGYSEGAMLAASICCEENRRFEQEGIPRRIKFAIFFAGSPPLAIEDGECTAKLADECGPVIDIPTLHVFGTNDPLVYCAVALYNSCNPDTAELYDHGLGHLVPRDADNVEQLGDILQKIIKKIQKAETAGTGTPCSEFTEFSDSTDCSKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXA4</accession>
    <name>A0ABR1VXA4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666762.1">
        <property type="nucleotide sequence ID" value="XM_066814800.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047860"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="78" mass="8312" checksum="FFBFEA06E3337925" modified="2025-10-08" version="1">MDSDFDVPYSGIKPDTAITMAFSSNTRLGHKEDGRPFILAKASPSTLTASSTTAFNLTVENNPPVEANGSHNAYPVCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXR7</accession>
    <name>A0ABR1VXR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665553.1">
        <property type="nucleotide sequence ID" value="XM_066813591.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046651"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="7"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="488" mass="55235" checksum="D5DE06511A6D51CA" modified="2025-10-08" version="1">MQDTINILSIPNELLGQIFDAIQDRASLAAAARTCHDLRDFAEARLYSHLSLRKREALEALRKLVDARPQRAGFVRQLDLVFSTVQYDNHLEGVTTADAVTSFPYLNSLTVESPRCNAMSRINSSEWGTDWAADMSRYLKLFLSASLLGETKCNASPLQNLTSWEVDRFWYTSASCPVFLMPNLEKLELSCVIVEAKEGDRELLRFEGKTNLKALVFTRSIVNSDSLDLLLKLPKALLRLELNEGVPRVVDSKMMATIRSRNSSLRLSNNSLRHLTLFLRSHQFLHDVPMPQLQVDLSGLPSLESLHLGPNSSRFQPRWALVGRLPRNLALLRLAGFDARSLRRRGSLLSDLRLGELGSDRARAKGLSMAIDLEPTSRGHRHSDMRDMLREFEQSARELRPSRDDDDGGGGGGFEIQITTAKPTRYIPPYLYQERRPQRVVRYISTRPDDGQFLERPYFELTGMPEDEADLKDQDDKAIELFASESVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXV9</accession>
    <name>A0ABR1VXV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin-like fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665674.1">
        <property type="nucleotide sequence ID" value="XM_066813712.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046772"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02972">
        <property type="entry name" value="DsbA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875:SF2">
        <property type="entry name" value="ACR183CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875">
        <property type="entry name" value="OS09G0542200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="21896" checksum="5DCB80DC63C9AE5C" modified="2025-10-08" version="1">MAVPPKYAAHKLRFRAPASGEAAPGLSSSMHTLEVYLDYVCPFSAKQFNTLYHMVVPLVQGSAEWSAGLEIIFRHQVQPWHPSSTLTHEAAVAVLKVAPESVVNEPRNQTYKRLAKVAAGVGVDEAKVYELLEISDKPGPDGSLNSGNQVTNDLKVLIKMARLVSIHVSPTVVYDGLVANDISSSWTKEQWTEFLTKNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W0P5</accession>
    <name>A0ABR1W0P5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666694.1">
        <property type="nucleotide sequence ID" value="XM_066814732.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047792"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="52290" checksum="336555902E0E088F" modified="2025-10-08" version="1">MSKRTSLLRGLPCPFPQPPRNNSTSNNTNTATVPRTNPPRKHSNTPNINIATAKLSKNWRKAIDAVRQTLASTSAAAKTRRQLSSSSNNTTPESSQAARFTRKINEAIFDPVTPQNGWAGRHRGGTRYRSVKVLLTYWAETDDPAFGASAAARALADVFQNRYGFDVLVWLIPVMQPQQALAAKLRQFARDDADARQRLGESLLIFWYGGPAREDESDGGPPLWFGESFTGPTINSHIVPQILGAGKSDVLTLYDSPHALHGYNVTGPGLCEHLGATAYNGVVAGFAANYSSADSIPNGNTDHRRYSLSFTRALIQILDHPDRAAQGISVLDIHRKLVNRYQMAAAAGRGSESDEAKEAALAWRMAALAPKRPAPDARVLPPVPVPAAGRRGPASIVLAQLGRQTLETTVAPSPTENTQKGPGDNDENESEKEMDDGAVEVTMRMRLRPPADTVNVGRWKEWILDAPPEANQLVFIQAQDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W0Y6</accession>
    <name>A0ABR1W0Y6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666784.1">
        <property type="nucleotide sequence ID" value="XM_066814822.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047882"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36839">
        <property type="entry name" value="METALLO-BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G12770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36839:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G12770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="86"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="327" mass="36190" checksum="98A7F9C3B4910A06" modified="2025-10-08" version="1">MSAEGELQYDPDRTGSWLVCTACGTQFPTADRQAAFTTLDELRNSGHRNTFTPLFSRTSLPSSGDDDGGDSWAFTSIVTEPKVAIGQRAILIRTPRHGNVLWDCVTLLDEWTFIQIRALGGLTAIVISHPHYYSTHLEWARAFNCPVYLAAEDKEWLAQTDEEHQVFVPEGTEEMELELKPSNYDESGQPQQQLQQASPSGIKILKLGGHFPGSCVLLYRRRLLIADTLLTTPAGLGSWHADAVGEARHRPRGMNSYAFMWSIPNMIPLPPAELVRMWNILKSTSSGRRTARSSTRTSSRPRPGCGGGCSTACRSRFGIWGTGIMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7R7</accession>
    <name>A0ABR1W7R7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667003.1">
        <property type="nucleotide sequence ID" value="XM_066811661.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044721"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="80" mass="8552" checksum="C8F9220BEE05810D" modified="2025-10-08" version="1">MLLEFGTEEDVLSVLGEDIVVLEAVVPVEIVEGFDVVAEAELVVVDEINVEVVEDEPGSDGVRTLEVAMLELALDVAVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8G9</accession>
    <name>A0ABR1W8G9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisome assembly protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Peroxin-12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_007597</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667254.1">
        <property type="nucleotide sequence ID" value="XM_066811912.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044972"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017375">
        <property type="entry name" value="PEX12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888:SF0">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pex N-terminal" evidence="17">
        <location>
            <begin position="25"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="310"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8079779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="469" mass="52066" checksum="5344231033E83D89" modified="2025-10-08" version="1">MEFVTALRGTFDDQKPSLFELLSEQQLNALLPPTLRYLLTVATQRYPRYLLRALNSFDELYALLMLLVERHYLRTRGGSFTEHFYGLKREASAGGGGEIPRASHGAASVVRETLKLGRSDIWRNLLVSVAAPYLKRRLDEAHEIEAPRALLGANYTRLPPNPTPSQRFLWCYRWFLRRVYPSVHAACGFAVLAFNLAYLFDGSKYHHPLLWLIGTRVRRMNMSDYKALEELENKPTLGGGGRLGQNSNAAAAAGTSSSFLSPRTLGPKILGSLSVLLPTSIFALKFLEWWYASDFAKQLSRKAAENLELPPPVATGLRNSQQQQGKAGSPNDKKQDAQNGNDEKKQQQQKQKPKTPQEEDIERAANAPIATPSMLPIHVVPAPADSQDCPICEAEIVTPTACQTGVVYCYTCIHRWVEGTHQRQEDFMSGTGAGGGVDRLGRWESGEGRCAVTGRRVLGGTEGLRRIMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W993</accession>
    <name>A0ABR1W993_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007883</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667540.1">
        <property type="nucleotide sequence ID" value="XM_066812198.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045258"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF50">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="34"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="257" mass="29239" checksum="1906923EEB67B65B" modified="2025-10-08" version="1">MFPKSSMNLLHHFWIKTLGYVVHPKIPRDGIRRVTDVGTGTAIWLFDAREHLPDDAQLVGFDISFDAAPPLEVLPPNVRLQHWDVREAIPDGLEGSFDIIHLRFLAFVLLNHEIPGVISRLFQMLKPGGYIQWDEADMETLRFDKARAESKTENLEALYRLLEAQDPRLKPTWANHLPELFSEAGFVDVEKDAKDAPPHVAFQFHDVGLMIHELIARKIQDKHMASELRRLLPAAVAETKNGAYGTSLRFSVIARKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9A4</accession>
    <name>A0ABR1W9A4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007886</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667543.1">
        <property type="nucleotide sequence ID" value="XM_066812201.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045261"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="205" mass="22853" checksum="82E306BB32BBA602" modified="2025-10-08" version="1">MADLPVLSDTPLSHPNCCLSLSSRLLETLKSLFRNESRGSGEAEPSSFSGLVLSVGCGSGLLENLLHTYLTQEEPKMTSMRVEGAEVATDASTIMAYLPEDRANTVAGTWALCRRAEDATVLMFVYPRSVDLVRRYVDAFLGWDKVRTIVWLGPQADWEVFRPELEKQHWLLETTQVTIREGAECGIGEYEMMAVLQVIDHKSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9D3</accession>
    <name>A0ABR1W9D3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667132.1">
        <property type="nucleotide sequence ID" value="XM_066811790.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044850"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF158">
        <property type="entry name" value="ENOYL-COA HYDRATASE (AFU_ORTHOLOGUE AFUA_2G10650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="3">
        <location>
            <begin position="34"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="331" mass="35104" checksum="CF77BAE2D636C334" modified="2025-10-08" version="1">MSSASSAGLPAGLASPPPPVPDTLVSFPAPHVLLVTLNRPKQLNCIPRPQHFALERLWDWYDDESTLRCAVITGTGRAFCAGADLKEWNAINTRSDAAAPAAEPAATTNSPSGAPSQAAITATGANNTPRQQQQQQQPDDRPTSRMPRGGFGGMSNRGGAKPILAAANGLCFGGGMEMAINCDMVIASASARFSLPEVTIGVIALAGALPRLVRSVGRQRASEMAMSGKQYTAAEMREWGLVNEIVPAEAGSDGVVEKALEWARRIAGNSPDAVIVSREGLKLGWEGVGPEMGTDMLIKGWYGRIEKGENMVEGVRSFNEKRKPVWKDSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9I8</accession>
    <name>A0ABR1W9I8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease P/MRP protein subunit POP5</fullName>
            <ecNumber evidence="5">3.1.26.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007949</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the eukaryotic/archaeal RNase P protein component 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667606.1">
        <property type="nucleotide sequence ID" value="XM_066812264.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045324"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3250">
        <property type="entry name" value="Ribonuclease P, Pop5 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002759">
        <property type="entry name" value="Pop5/Rpp14/Rnp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016819">
        <property type="entry name" value="RNase_P/MRP_POP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038085">
        <property type="entry name" value="Rnp2-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15441">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15441:SF2">
        <property type="entry name" value="RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01900">
        <property type="entry name" value="RNase_P_Rpp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023803">
        <property type="entry name" value="Ribonuclease_P_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160350">
        <property type="entry name" value="Rnp2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR023803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="190" mass="20979" checksum="A5B8AA5137718CA1" modified="2025-10-08" version="1">MVRIKERYLLVNILYPSEIGVKPGVPDVVVINQPTTDKLTPQALLRGIRAEVGDTFGDFGSGALEGGGLQVKYLSNATSTFILRITRAQYRMLWTALTFMDHVPVRDGKPCTFRVVHVSGTIRKVEEAAIRHARNLMFAVKDQAGEKDKAALEAMFSQAKRMRQAAAVMPTPLNVEDDSGDEDMVDISDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9W5</accession>
    <name>A0ABR1W9W5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667769.1">
        <property type="nucleotide sequence ID" value="XM_066812427.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045487"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="134"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="364" mass="40729" checksum="9A24CB9500C5A278" modified="2025-10-08" version="1">MSDEDPEILTVNAENANNPVTEEVTFRPQFLERPRLGTRDYETQMMLEDVVDSDVEGLPPYNPLEDESGSRTAQSPPKTRQPPSDWYIPDQLPYTHTHIEELGGWPQRLLHVESMVSYEWTSGNVYGGHKEPAYCAVSYTWGRWQLPNDDGETGVESAAIKVHGVPWRIPRIDPVHFRPADLTQALQRACALGDPPVHFVWLDIACMDQRRGPAASREVGRQASIFLRASGVAVWLARTGGDDGSTARLVRRLALLERAAGLLRTARSGTTAHEGRAGTATQQDEQRHFRLRFDSVAQTEVLDGVREMLCDPWFTGIWTLQEAFLARKAFFLLAKQPLRVPLLSPAGGRSPPPMPAKCTLFLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA21</accession>
    <name>A0ABR1WA21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5672 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667825.1">
        <property type="nucleotide sequence ID" value="XM_066812483.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045543"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043729">
        <property type="entry name" value="DUF5672"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18922">
        <property type="entry name" value="DUF5672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5672" evidence="1">
        <location>
            <begin position="39"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="210" mass="24297" checksum="EC60786CD0348D40" modified="2025-10-08" version="1">MLHFATVLGPAWSLVLFTLEEHWKMPYSPAFVRAVQRGQIEIRYLPPATQLTSSRDVLDFLTRPWIWEQVESAHRVLMFQLDSILCSKSMYTVEAFFEYDFVGAPIDPKYGAGYNGGLSLRNPKLFASITREADFGQSGQEFEDQWFYAEALERGPVLPTQLAAREFAVETIYQERALGYHQPERWQHDKMEEIREWGPEVGMLVGRRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAU0</accession>
    <name>A0ABR1WAU0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Toxin biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667642.1">
        <property type="nucleotide sequence ID" value="XM_066812300.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045360"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="7">
        <location>
            <begin position="267"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="104"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="117"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="415" mass="45534" checksum="A09548FBD0E43299" modified="2025-10-08" version="1">MGFQDTANTIALMQAIVSAFLFVAVFTMLVLAAPRNSVAERYSGAFVLAGLVCVFQSSLHFWCRNKGWVLLLVTTAWTTYWHALEMLLVSKVCLADIQELAGEKNKHHKPPGAASKSDGDSESTKESRSKSGSGSGSAWQLAIITSALLCKWRRIGTKWQIPILPNFSPDGSVPSKGAFLFRALLKITSSSLILSMFTVAPPPDPNLIAIERQPVFSRLDDISAADVVFRVTSTAVFLINVALMVTTWYYLVCVVSVVLGLAGPEDCPPFYGSLSNAYTLRGLWRNIHQGLRKCVLGPADAFADSALPLPRGTFASRSIRLVLAFGISAVIHAPADLAIGLSFAEAGQFYFFSMQAIGIIMESGVQDLWFRTGIHFPRVLQKVLGYVWVISWLCWITPSWSYTFMRHIDPVKDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB49</accession>
    <name>A0ABR1WB49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidoligase enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667221.1">
        <property type="nucleotide sequence ID" value="XM_066811879.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044939"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022025">
        <property type="entry name" value="Amidoligase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847:SF1">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12224">
        <property type="entry name" value="Amidoligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="838"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="932"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1064" mass="116544" checksum="5DECE752F99F5576" modified="2025-10-08" version="1">MAGNPSGKQDGGAAGTKRPAGANLGNGNTKRANTGIIDDMIKLVAVDDLLNVDFLGLSKLYHRHDRQVGDLGNPFQAVERWARRALPKAHWDSNTHVGHWMRSEKLGVVYMFKNGYCYDNGREFVTVPVYGRWLEYQGFKHFKSDEGAEWYTILDAGLPWFRTGNPESPFLNVGSWTMSRFGKPVIVGKDNKFYQSVLDAFRERNPATITNDGENEKIEEIEVPIKSLTMTNELELEPPRPYYRDMEEYGPCLRLLGGVSGTYSVTTANRVSRGRKPSGNNQNATSEETHPPPSPPVPPTPKTPGEPGETTTKTSQGLTTPGSNKFTGGAIDNKTSSGGTHAPTGKKTEEVPETTETIYRPNRGLHTPEKEQKSTTPTPAANTSVAVDNKGTTATSSQTTGKKHTAETTGSVQISNNFPTTSTGHGFGFIVPHPTGTQVQQPGTTGFSPNANVAHTEKNTIGVANTNAKTDAQAIAQERATIDAQIAAELADREALKSQSNTGSQPPVEGGAIAQSVLIDSSCKPFSVEAQEAFKHFVENEAKKDTVNPDEVNARTQTSPKDQPKVKLEELHGQSQRLSFGVEFEFVMPVVLEEWLNGSDIDEELLPALNVIPLNLKNRVPRDSFDYEENEFAELHMRRNWVDEQILATLIGLGVPVIDDSGKGGQGRDVLVNADPKAENISSDRAYWGWKIQKDDSVEIPARVSAAYSFRKTRWIGVELISPAYWATPKNLGEVRRVLRGLSSKLRFVTPETSGLHVHVGRGKSSFSLVELKRLAGLCYAADPLLSQLHPASRHVNQWCKSNRFYSSLAHGMNTENAIIGRRSPVITCSIVRQGGLPQEPLANPQRLGGATKESGQRPADTPRFKRAIKRGGLPSEAFSQDKYEDEWLDDMTKEDLDDRFFAYNFTRYMCEDYAGNLDSVNSYLAGLESSSNGSRLGGGGSTSSTSSSSGSGFGPGTVSGNSREHRCDKSSRTVEFRQAAATLDPDSVVAWVRVVVNLTCVAVHTTHDEYARLVHCCAKAEREPAWYDAFDLLVDLDMPRTAQFIQGRMLSRASRTPWAALPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBD7</accession>
    <name>A0ABR1WBD7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008633</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668290.1">
        <property type="nucleotide sequence ID" value="XM_066812948.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046008"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050375">
        <property type="entry name" value="MFS_TsgA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702">
        <property type="entry name" value="L-FUCOSE-PROTON SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702:SF3">
        <property type="entry name" value="PROTEIN TSGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="455" mass="48567" checksum="9D196089008B11F7" modified="2025-10-08" version="1">MAGGGLTTAPAQVTGGYLTGRALIYPLSLVISLFFLWGFSYGLLDVLNKHFQTVLGITKLESTGLQVVYFGGGYLVFSPVAAEVLKRYGYKATILMGLTFYSIGAIMFWPTAHFSNPANPSAAFGGFVACTFIIACGLATLETSANSYAVVIVLERCGVFHRPLIASKFFFSGENANSLTNVQFVYLAVACAGAAIGVLFFFAKLPEVSKEALATQTTADNPAIDHYGAEVGSGPLYKQYNMIFAFIAQFCYVGAQVTIASFFINYASESGGFTDAEGSNMLSYALITFTVGRFAATALATVFQADFMLMVYACVAIAINAYVASAHGSGGVGALIAIFFFEAPMYPTIFTLGTANLGRHTERAAGILVMGVSGGAVFTPIQGAIADKFGTRISYLVPLCGFLYVLGYVTIHWLRHGRHIMRVKDVVNTHPTGIAADHTSEDEKKAEAVAVERRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBZ0</accession>
    <name>A0ABR1WBZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667128.1">
        <property type="nucleotide sequence ID" value="XM_066811786.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044846"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="163" mass="17622" checksum="3A024827E9A942F5" modified="2025-10-08" version="1">MAQHVPSGITVYSASRYNSFIITANDTTQPEYRPKDVTLPAKPTDSIAEWAIVAQHSLAAGGPFVLANVTVPGGGNGKTPCGGGSTKRVGYGDHKEEHHRYVGATGPSGVMHNHFTTATLPSWVDFDLSSDFEFFDDCNVHVLRTSFGDVLQTVFFDRLPEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC86</accession>
    <name>A0ABR1WC86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007561</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667218.1">
        <property type="nucleotide sequence ID" value="XM_066811876.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044936"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10917">
        <property type="entry name" value="CE4_NodB_like_6s_7s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF6">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="NodB homology" evidence="8">
        <location>
            <begin position="584"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8079743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="786" mass="87101" checksum="CC898F3DA6EA912D" modified="2025-10-08" version="1">MNATSVDGGVLTFTPSETVESYIYEQFGCTTAIAQGYDTISFDIKGPAAASVSLEIQTQPNCDPETTEYNSTYFTIDGLSGALETIQVPLSSWPDANLNGVIGFLWYGFSKGLTGTDNVWQLDNVQLLCGGTPAPPPPPTTDPVTVTVSPPSPPPPPTTTRRPTSTCRWWDWDCDGDDDDDDDWDRVPRPTAPPGPPKPTGPPGPPAVQRREIEERERATELATRQDECSLLAIDDFESQSRLTFLFYNALLKSSSDDGTMKSVVVRNNKVTFTPQNTDSYWYSQVGCMDARAYGGISLRITAPAGSQFDVQLGSTRGACGTEDTKSVTLTTRQLGWTFDGTERLYSIPFSKFSGVDLSKLETFYISNLKRPVTFGPLAMYCGDTVREFVVKPPIQPSEPTATVGAPPSRATNIVVDQFKNADTNALGEWHGGDEGLDLTFRNNKMTLKTNDSDLMWNTQLTEKCRDMRDWQDAYLHIAYSGSNKFSIALQQHNEKCDDSIQPFPETWDSLEAARYSDGGDIYIPMNHFNVNFERLVGFALKGFYTTDATVFSKLEIVNQVPRGWTVPEKLPSGQFVFACKRPNSFAFAIDDGDPAFARQVMDTIKDEGIKVTFFTVGAALQDPSTNLSSLYNDMAARGHQVAMHSYTHPALEGLPDEASIDWEYSNMIRAVAATFDGMHTPYFRAPFGTEGARMRQRLAAVIDDPYIVQWSVDVEDWLWAESDTPEKQLDAFKRDVDKGGNLVVMHYLYPSTVGYLKQFIQIAKATGKQLMRVDQCMMDPNAPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCE1</accession>
    <name>A0ABR1WCE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transporter SEO1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008997</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668654.1">
        <property type="nucleotide sequence ID" value="XM_066813312.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046372"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF15">
        <property type="entry name" value="TRANSPORTER SEO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8081179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="476" mass="53216" checksum="13AD39EA9FE5E4AF" modified="2025-10-08" version="1">MASETKRRWNDFSWYAPEDTKEERRFIRKLDLLIVPYAFVSYWVKYIDQANINNAYVAGMKEDLGFHGNELVQLQTLYIVGAVVGQLPFLFLFTYVPLNILIPFMDVCWGIFTLLQFRVSGFAEIAAYRFLVGFFEAAFFPVMHYLFGSWYRGDEIGRRGGIFYVGLSLGTLTAGLIQAGASARLDGVSGLAGWRWMSIICALITIPIGMLGYFVIPGTPDQPNRLVLTEDDVVIGEKRLKRAGHQSHGKLRLRNLKSALSRPQFWAIIVVDVFFWNAGLASSTGSFLLWIKSLGRYSQARTNELGTIAPALGIFYTLLVCFLSDLALGPAWAITLAHVWNGLGLLILTIWNVPEPAKWFAYATNYSSQAMSSVLHGWVNAQLRDAPAERAFTLVLINAISQSTTAWTPLLVFPTVEAPRFPKGYAFCLACAVVLIVLVHVLNTYLKRKEAKSIQIDVVENPEAASLDARTADNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLB5</accession>
    <name>A0ABR1WLB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005557</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668795.1">
        <property type="nucleotide sequence ID" value="XM_066809872.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042932"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF16">
        <property type="entry name" value="ATP-DEPENDENT HELICASE ULS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="44"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="356"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="524" mass="59445" checksum="7C226D7B73D65535" modified="2025-10-08" version="1">MSFQTGDDPYLASFNDGPLKSSSNLKRQPSPISTTDQAGSSKRFRLEPAYGGSILADDLGLGKTIQALALILSRPAAKRAKSKTTLIVVPLSLLKQWEDEFERKVEPDILDIVTYHGPKQKKNMRWAELKSHDVVLTTYDMLSGELRKKRSTENSRDLNLLSPDSHFHRVILDEAQLIKDPGTDRSRAVTELEADFRLCLTGTPIMNSIDELFALIQFLRIEPYNDQDVFDEEIGAPLREELTHNAKSALAKVHELLDQIMLRRTKTDRVLGQPIVDLPERIEVDWPVTFSKEERDMYDTLDGNEDKSIWPKKGAALVKTMRLRQLCLHPDLLPDALQDRDLEPGKTSSKVDSALKLLDSIWQADERAKVIVFSGFTTFLDKFRDLLIAGGFTKMIGTNIQRYDGKTNVKARDDALKYFRERAKLLLMSTKAGSMGLNIAWATHVLLMEPEYNPYVEEQAIGRAHRVGQERVLTVYRLFVQGTMEEEIRKMQNDKKEHVRLVLGDEEVPSDEETSSDSDEVSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLD9</accession>
    <name>A0ABR1WLD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668839.1">
        <property type="nucleotide sequence ID" value="XM_066809916.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042976"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="79" mass="8654" checksum="75DE59CB2FCE9C9E" modified="2025-10-08" version="1">MNGVVAWGLRLKRIVNEQVLATATCSDPLRSSQWISATPEMPGTRLGGFTTNVLYFKIVGHNENLCGASTNPNEYLTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMD6</accession>
    <name>A0ABR1WMD6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669208.1">
        <property type="nucleotide sequence ID" value="XM_066810285.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043345"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="40199" checksum="95167B4B0A2737C5" modified="2025-10-08" version="1">MAVSIQLQHELKERLASLTDALGGDLPVDEAVLDALPRGTKSVSAHSYGVSAWSFTAKVSGLDAEDRPIEFFMKYVARDLGGAQLKGEFTGMTELHRAAPNLVPKPIAWGQLKTAAPATFFILVEFKEFAPGLPNPVKLGSRLAAMHQNTESPDAKFGFHLQTYDGARIQDVTQQDKWTPFFSNLLAEAYRQDVQANGLWPELDVVYNRVQSHLIPRLIGALEGDGRCVTPVLIHGDLWDGNICNDAETGDPWIFDCATYYAHNEMELGIWRAERHQLKAKIYRREYLRHYEASEPEDEWEDRILLYSAKTNFMFSVCFPGGAPSRKVVFNDMLYLIQKYVPWEEDSEVRSQLSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMW2</accession>
    <name>A0ABR1WMW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669390.1">
        <property type="nucleotide sequence ID" value="XM_066810467.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043527"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="717"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="744"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="862" mass="94350" checksum="4B511DB73F0E276B" modified="2025-10-08" version="1">MAMQAVADVSKDRGHGKSGSTGSARSIPHPSMPASPTLTNPDMILPDWDPGNVSSPDRSQSPLMMWKSANGFDMNQFDLGAPAFPAAPITPTTPIIYGNGTMLSDIGEVTENESTVGGPGARRASSVYSLQQPEAMNMVYETLRKKHSGQTILSRDRDRRFSMDSTSTITNGDNHRVFADFDDTASVDDSVFQGDDEESNAASYAYDEASITGDETPTTQEFSETFTPTQEDRYSTVLSRRAEQILANAKRRLTTMEGNLNRARTSMSSYGSDSTPSPSFQRPVTAIHSTNESTGPKNPRGHSRISSENNVPTEGKSAPMFSPERRARWAQQADPFLEEDEEEEEGSPKVSLYGNQTFAKSKASLHDTKVVLEPLDEDEVPQNLENARASIESSKLESFLSPTFGSFNEKGLRRSASTAQMRELKDHMTDPKGRLSALRDQAREDNMKRRSLSSLRTPSPFTHARVEQWYAATNGDTEQADALSENAASVNGKTTPAQEEDTKARVVSGLSDEISVYTDLEEPYSPKTKLAPAEIHVQSPSKTGLEFDDDDDLQTEDGYEDEAGDGFVDVVDLDSESGESSYHDSVQNQMSHEDREDAFDYEHFFLHSAMGSMTQRRMLQKGNRDSYSSEYSEDSVETARGPLVVTKRGRRRGSDVSVSSTDSFATATEGRLTRAETSAAEESPEETMPERSRSHSPEGAKRLTFGFSSIAGDTTMEQVQQRASIHQRPATSTAAYKHRPGAASISSTGTTRSSPVVHQSRSNGVLTPGASPRESPDQGLKQISESLMSETASICESVQGGDQQAIEMLPKEDQILVQRLVASLGKCVLGITENGRASSESRLYRRRIDLARKILEGVEPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNL6</accession>
    <name>A0ABR1WNL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669603.1">
        <property type="nucleotide sequence ID" value="XM_066810680.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043740"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="46212" checksum="E522DEFEBBF6EA91" modified="2025-10-08" version="1">MAMTYSSCPQAVTDLQSCVCSKGNNPSSLQAAISKSISYSCGSTATDDQASASQVYAGYCNQAKITPFPKPTQTVSQYIMDFPEWAELAPCAASAVSYNVIKISKPNDLQTYDLCPTDASLLAPCVCQKNQNSLRVSQAINTSAKSSCSAHTADVSSAQALFAAYCGLNNGTSSFPTPTNPPGDMTYYVTGMAEYASLAPCAQSALSSGVLSQTYDLCPPGPKALASCACIKEGMPGLVSAVITSGVSLECMGHLLQCCKGLTKPAGVTESVEQTSPAARTGSGNGSGSGPQPTGGNGVNGGSGSSSDNSADASKETKSNVPVIAGAVVGVVLGLGAIGAVLFTSCGGAAMPREEATQNLTNSPDDGAGKPELDSTALAVMPTAGSPSVSSLKPVSPSRADNVSPVSAHGPPKPELSSTPVPRPQPELQGNHVSEAYGQPLHEAPGQFHGERTTQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNL9</accession>
    <name>A0ABR1WNL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endoplasmic reticulum chaperone BiP</fullName>
            <ecNumber evidence="3">3.6.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Immunoglobulin heavy chain-binding protein homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_005908</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.10" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669146.1">
        <property type="nucleotide sequence ID" value="XM_066810223.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043283"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10241">
        <property type="entry name" value="ASKHA_NBD_HSP70_BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042050">
        <property type="entry name" value="BIP_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047128454" description="Endoplasmic reticulum chaperone BiP" evidence="13">
        <location>
            <begin position="35"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="645"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8084637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="665" mass="72696" checksum="7B2A49D50FB8CD9B" modified="2025-10-08" version="1">MSRSSQSSWALGLGMIAWICLLFSPLAFVQTVRADEVSEYGTVIGIDLGTTYSCVGVMQKGKVEILVNDQGNRITPSYVAFTEEERLVGDAAKQQAAGNPYNTIFDVKRFIGRKFEEKEVQTDLKHFPYKVVNKSGKPVIEVAVSGSKKQLTPEEVSAVILGKMKEVAEAYLGKKVTHAVVTVPAYFNDNQRQATKDAGVIAGLNVLRIVNEPTAAAIAYGLDKTGGERHIIVYDLGGGTFDVSLLSIDDGIFEVLATAGDTHLGGEDFDQRVINHFAKSYNKKNNVDITKDLKAMGKLKREAEKAKRTLSSQMSTRIEIEAFFDGKDFSETLTRAKFEELNMDLFKRTLKPVKQVLDDAKLKKEEIDDIVLVGGSTRIPKVQTLLEEFFAGKKASKGINPDEAVAFGAAVQAGVLSGEEGTEDIVLMDVNPLTLGIETTGGVMTKLIPRNTAIPTRKSQIFSTAADNQPVVLIQVFEGERSMTKDNNLLGKFELTGIPPAPRGQPQIEVSFELDANGILKVSAHDKGTGKQESITITNDKGRLTQDEIDRMVAEAEKYAEEDKATRERIEARNGLENYAFNLKNQVNDEEGLGGKIDEEDKETIMDAVKEATDWLDENASSATAEDFEEQKEKLSNVAYPITSKLYGGSAPGGEDDEPSGHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNM1</accession>
    <name>A0ABR1WNM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669617.1">
        <property type="nucleotide sequence ID" value="XM_066810694.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043754"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046972109" description="Conidiation-specific protein 13" evidence="1">
        <location>
            <begin position="21"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="34477" checksum="B7FBD1CBAB8AC977" modified="2025-10-08" version="1">MGPFLAVFLILLGFLGAALGDNNQTHVPPNVPPKAEDKPDEKPVVTPELRFNLAAGLYDHLPPTWGYWKGWESGWIPKPCREAAEQRQLNPWEMEVYSVKFTDCDEPWTICRHFSDSSSIVSMTFGKIPLGMREYVSTIVTLPSLGPGAAGVTYSETDIPVIGIRYGFFQEELLAHEISHILDFHALKQYTNGSDFSTGSWWKGNYSLDGAAVSTYALTKWQENFAEAGGAALYDLVVPGGLADITTDAKSVSHVVSTYKNVLGDIIKPRSKPKCTKRWANHGVVPVDDKKAKGIEQIENPSKKEIKCVLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNX4</accession>
    <name>A0ABR1WNX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669735.1">
        <property type="nucleotide sequence ID" value="XM_066810812.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043872"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021822">
        <property type="entry name" value="DUF3405"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205:SF2">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11885">
        <property type="entry name" value="DUF3405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="637" mass="73125" checksum="E7C6CF7F3A360A02" modified="2025-10-08" version="1">MSTLANRTANRKPAHEAALSPAGPVKGISQKPYIFNPYPEYNGKDWVESKKAKFMQCDGPDGSLLDDVKVFKGTPRLFPKPSFGSYDVLDIDGDLCFERDTRLGPYGFLKDADHKRTQAQWDAINWGQLQEKCVHKNKVRFHMQGPPNLFIDSVYGPLDAPTMSELRRSRRPSILEDAKKHSHRRRRSVTEDEPEESGKHDKRQGSTNDKENEEKESGQKPVKEQRTALLIRTYTGKTYSDNDKHILRSLISELSLRTGGQYQVFLLVQVKDNDLPIWEKYEAYRTVVLNSVPLEFADMTILWDDQVVRSMYPKLGAEQASVHIAQWLSVQRFAQEYPEFDYVWNWELDSRLTGHHYDFLEKLVSFARKQPRRGLWERNERFYIPAMHGDYDTDFRREVESHAVNGSVWGPPALPFIHPIGPKPPVKIPEDDDYEWGVGEDADVITLAPIFDPVGSGWINWDFVWGFSDATHATVDVPRRVTIITQSRVSKRLLDIMHVENQRGNHVFSEMGPQTVALLHGLKAVYAPMPVFFDRSWPTKSLARWFNGGPNGDAGGFASAQAWGHEGRYSGSTWYYRANPPQRLYLNWMGWEDTGIGGPEWEAKWGRPCLPPMLLHPIKDVEETEPGYESESWLPYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP03</accession>
    <name>A0ABR1WP03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006514</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-A beta-lactamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669752.1">
        <property type="nucleotide sequence ID" value="XM_066810829.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043889"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="5"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="395" mass="43065" checksum="888DB452BD34458E" modified="2025-10-08" version="1">MKNFEQSVEKAVADGVVLGAVVCAKGKVNYSKVFGNRTLKPQAEQMERDTVFVLASMTKLMTSIAVLQLVERGAVKLDDDVAPLLPVLAKQPILTGFGEDSTPITKERTGPITLRHLLTHSVGGTYEFANGDVLQWRKIQGLLGKPAVTVEEAFGHPLLYEPGESWCYGTGSDWAGKVVEALSGLSLEDYMKEHIWSPLGIKDITFWPAARPDMANRMCSMSIRDTRSGKAVQSRKPIEMAPGAQEAFGGQGAYATMGDYTEILNSLMVDDERLLKKATTAAMFRPQLTGDSRQALNEAMAHPEWAVGYYPPGTYNWGLGGLLVEGKTESWRKPGTLLWGGAINSAWFIDRVTGVCGAFGCNLLPSADPQIELLMKGFEEDIYGKAAADRPKTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPI9</accession>
    <name>A0ABR1WPI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668904.1">
        <property type="nucleotide sequence ID" value="XM_066809981.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043041"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="155" mass="17932" checksum="D5BFA228BFA83A47" modified="2025-10-08" version="1">MGSLAAHLVNQGRRREEMLRQCAKIRDWEGKIKLLVIAEHHVCRFLWELHHRGKMPEDRFCWLVDQVLFRYAEARPQPIVSMAVLSEILGPMPSMRVDYKVEKPSGVWEKYEGTMQERSAKEKEKQQRAAKGKEKEQPKSSTSPPASFADVASKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPX0</accession>
    <name>A0ABR1WPX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006734</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669972.1">
        <property type="nucleotide sequence ID" value="XM_066811049.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044109"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF3">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="91"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="551" mass="59376" checksum="34F31480F3424D75" modified="2025-10-08" version="1">MGGPGQDRQPSWEVVAKEHAAKQLNNIPAEWRLPRAKLDQLSGVGTADEGRLIRLQAAKKSGLLSERELDITENHTARDLLPKLAAGELSSVEVTTSCLTEIFFNEAIERAKEADQYLEKNGKVRGPLHGLPISMKDSFVVKGRYASVGYVEYLRQPIPEDESALVKLLQDAGAVLYCKTNVPQTMMTADSENNIFSRTLNPHHTALNAGGSTGGEGALLAFRGSPLGVGTDIAGSIRIPSVCCGVYGFKPTADRVPFAGQNSCPFPRNHLPGIIPAAGPMANTLADLRLFMDIVFAQGPWRYDGTAIDVPWRSLPAKAEGEKLVIGVAPEDEEFKLHPPVKRTIENAAKKLEAAGHTIVHLPADPTRSMALGGRLAFAFFGLEGAPSNEQMEAEFGEPLVQSLAVGVHPYSAANPPPLAAEWGGAKKVAEWHRLRAEYRDSWRRAWIEHGLDVVLAPGATSTAVRHDAFGVPVYTASWNVADYPACIIPYGCSSKELDPTAMKGHAAFDADYTPELQDGAPCSIQVITPTFKDEECLHAASIIDKVLNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ00</accession>
    <name>A0ABR1WQ00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670129.1">
        <property type="nucleotide sequence ID" value="XM_066811206.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044266"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045476818" evidence="1">
        <location>
            <begin position="18"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="205" mass="21912" checksum="4EE4D611A74827D2" modified="2025-10-08" version="1">MQFTYAASLLLAGLAAASPIERRGGSAVDMVLAIAPGSKSCDGSADCRTAQQAAPFMIQSFQDYKVYAAGQIAGVLALMAYESGDFKYKHNVSPGRPGQGTANMQMYPNNVKYAASIPDLKTKAASFTDNSPDAQKNELLAMVTDDKYNFGSGAWYLMTQCDSATQQALAKGDDAGFAAYMKCVGVTVTDDRNAYWQRAKKAFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQK5</accession>
    <name>A0ABR1WQK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006568</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669806.1">
        <property type="nucleotide sequence ID" value="XM_066810883.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043943"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8085297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="557" mass="62343" checksum="4202B51CF6E60E75" modified="2025-10-08" version="1">MATSPLLVNACIGTLLAVIAIQAVAFLADTWKKRSLMKRLANQGKPMPPFNTLMGHLLAAKRAAPEAHSVYILNRLAAKHAPQGAYYVDFTPMAWPMLVVTDPALATQVVEHPIVGAAKPDELYAWFHPITNGASLFTQNGVAWKRDRDYFLPFFSNQNLDASVPFVVGQMAIFRDKLREKAREGGSSGSGMFVLEPLILSMMNDIIGKLVLNADLGTQHGSHPLATTMLRQLRLKFAVNNPLDNLGQLNPMKVFNLWNNSRMLDNHIKSQIDTRLQAWRLKKTQDEQNDFKSLLDVALESYMNQESTSSSQTDVSAAFSKTLCSQMRMFFFAGYDSTASTMAYCCYTAWNHPEALRKMRAEHDQVFGQRPDAALNAISTNPAILNALPYTTAVIKETMRLFPAANGIRQGHRDLVLRDAQGNQYPTEGCSVQMLHYAIQRSLKVWARPAEFLPERFLVEPGHELYPAKGAWRPFEYGPRLCTGQQLVMKELKAFLVLLAREFDIKECYNEIDGDSKRDLTHVDFEKAHLVEAGAAHPRANLPCRVSFSGYQTSTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WR94</accession>
    <name>A0ABR1WR94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006266</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669504.1">
        <property type="nucleotide sequence ID" value="XM_066810581.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043641"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="372" mass="37604" checksum="6B9A555F6F332BA6" modified="2025-10-08" version="1">MSRPPYGIFLPLPLLLASFFVLIPIRVVPLVFGQQFSATCYAPDGTPASDGSYIPCNFSGGASMCCPTNSSSTNGNGGDPRSGGGGSRDSCTEGGLCIGQSDGKTRRGYCTDQSWKSSACVNICTNPSAGGSSSGAAILNYCPDEQNTYCCGDGNTTCCGTSFAHTLAGSATVTLSTVISTAFVTYTPSASAENSHPPLSGAAREALSTGGKAGVGIGAGVGGLAIVAVASALVYRARRRRQKQKQSSKMDEAEGEGSRGSSSATDQAAAATAAAAGANRRSSSTDGDPTSPVKTSELGGRALERTPGELDGEGARFEVPATAITTGGKREPGAIFELEGDPVVTAELGDESEVKSPQKSETGSSLRRSNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRN9</accession>
    <name>A0ABR1WRN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669503.1">
        <property type="nucleotide sequence ID" value="XM_066810580.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043640"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="77" mass="8409" checksum="57E09B17B6F844CC" modified="2025-10-08" version="1">MSSLNQNEPSAMGPREAALNAASRQQQKQEHEQPKATGAGVNTGAGTTREKTEAELQADRDYEERMEEEYAKRDGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWR1</accession>
    <name>A0ABR1WWR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670503.1">
        <property type="nucleotide sequence ID" value="XM_066806885.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039945"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="14883" checksum="338E92A4B507C91B" modified="2025-10-08" version="1">MPKPALADVREYQGYLAANVPIAEHETRFLDAADDLVCLADEPAAELPRGDDGEGDGEGEEGEAPVISLSLATAVAVIAPIMAFGIVPGYFGRLIVVLLVSVAVLWGLVHERVIGVHATRDFYICAGLYGMAMAVVAGIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXH6</accession>
    <name>A0ABR1WXH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prokaryotic-type class I peptide chain release factors domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002758</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670691.1">
        <property type="nucleotide sequence ID" value="XM_066807073.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040133"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052104">
        <property type="entry name" value="Mito_Release_Factor_mL62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075:SF54">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="3">
        <location>
            <begin position="62"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="191" mass="21866" checksum="C02AB46220F80F9E" modified="2025-10-08" version="1">MFQRPLRLLPSLVSSFNLAGRVPYRSVRHQAFDAAFEQDELEEARSWYASFNESKLPKGQSSYSRSSGPGGQHVNKTESKATTVWSFNDLTKVLPKLLHPGLRACKYYTARTQSITIQAQTQRSRTANTDENHQKLFEEVQKIYRASVPGETSDKKRKKYEALEKRFNADRLKTKKQQSAKKASRKASFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXK2</accession>
    <name>A0ABR1WXK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670752.1">
        <property type="nucleotide sequence ID" value="XM_066807134.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040194"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="308" mass="33930" checksum="157599A5FFFBABCC" modified="2025-10-08" version="1">MTTSASTNTFGKVAVVGNPGLEVLENNSWESVAFGNNGSQLLSVLAVGASPGTVPEQSDHQTLSPDGTVYAPPVAYECLLQYCIHQMRANWTNNTFHEEVVSSWTNQSQKCPDLSCRSPFIFTSRKTDTTFYIRGEVVASTASWLSEFLNGNVTDYSYRYGGASFSSEFSGAIWRAMNNSATGFTDLMGNLADRLSLSLREIPSQPRAVGQSFTASYVAFVRWAWLTLPVFELGASLLFLFITMMETKRKGVAPWRNDILAAFFHGFDQRPVGRGGGHSLWGEDRQLLAEFHQDDETGGRLVVSGRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXW3</accession>
    <name>A0ABR1WXW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670858.1">
        <property type="nucleotide sequence ID" value="XM_066807240.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040300"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="17848" checksum="508431E2C1D912CD" modified="2025-10-08" version="1">MLTTCFWNHIRHGWGCTPDPERAITFLSAAASNAALVENLALQAGMKKGGAAKGELVLAIFELANCFRHGWGIPKDSVAAKQYYETAANLGDTDAMNEVAWCYVEGFGCKKDKYSAAKYYRLAEQNGNKTLGNTWIWKDKYNPLTPMRMVVSTAKEVTRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYR2</accession>
    <name>A0ABR1WYR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671158.1">
        <property type="nucleotide sequence ID" value="XM_066807540.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040600"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF9">
        <property type="entry name" value="P450, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="63313" checksum="0C7C9F8FD9DC97F1" modified="2025-10-08" version="1">MSSESPFLGQWFGIFAYLGRHVLLHVLALLVVYIFANEIVRSRRRIPGLKGPKGWPIIGNLREVRVDAALKYRDWSETYGDVFQVQMGNIPVVVANSPAAVKALWITNSQALSSRPQTYTFHKVASGTSGFTIGTSPYDESLKRRKKGAAIALNRPAIQSYIPYLDLETKNFVQDLFVYGKGGTAAIDPLPMVQRLAMSLACTINWGTRVRSHEDDLFKEIVEVEEHMNRFRSTQSNLQDYIPILRLNPFNTQSAKAREMKARRARFMKRFDDELRDKIARGTNSPCIQASVIKFKEDRLNETELNSISLSMISGGFETVSNTIGFSLGFLAQRPDIQQRAFEEICKFQEVSSGNSPDPLCDAGDDQRCTYVAALAKEALRYFTIIPLVLPRESIRDINYEGVVIPKGTTFYMNAWACNYREHPVYHISTAHFSSPIVANPLQTTDRDLWHDPEVFRPERWIEQPDATLYTFGLGYRMCSAHMLAQRQLYLILMRTLSSFRLEPHGVVDCDPRTGKRDPSDLIMSARPYKILCIPRDGPRLARAVSDEYKQEPTTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZS7</accession>
    <name>A0ABR1WZS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TM7S3/TM198-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003634</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671567.1">
        <property type="nucleotide sequence ID" value="XM_066807949.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041009"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39469">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39469:SF1">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="7">
        <location>
            <begin position="96"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="320"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="396"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="474"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="678"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="803"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="862"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="941"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="18"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="335"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="351"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="369"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="538"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="565"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="678"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="812"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="941"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1135" mass="121377" checksum="8161909A9575B869" modified="2025-10-08" version="1">MSNTAAVQALGPVRRQDTTAVATTGPPGGETPTSTATPAATETAKTTAVSTTQTSGAPSTTAVLSPTAAPSALNGNNTPTNTTTSNVVTPGWGVAGAILIATGVVYTLIGIKNTWLNAFGSTAYLSSLCTTVLILYVMVLPVTNGIQGAYVVAVVCTGLLLGGGAIVFRDLTESLGCLLGGFCFSMWLLSLHEGGLLQGNTSGKVVFIVVFTLAGFALYFSRYTRAYGLMALMSFTGATVIVLGIDCYSRAGLKEFWAWIWDLNSNLFPLGATTYPITKGMRVELALTVLFCAIGMISQLRLWKVIQERRAKRAEDRAEARRQMDEEEANLGRQVEAKNARERREWEATYGQRNTASPSISQDSGVGDVGEKPGRIDDSINKETPGETVIELAELPESSPAPPPQPAAGGLVTSDPKEESNVTVRVSQDETPVNDDSLPAMPEPAQLNGEQETNEPARPVSQISVVAENAPVKSAGPEIIPLPFQIPEHMDRDSDDEDDRSSFATFADEDRSVTFGQRDSRGSLGNRLSVESGNLFRKLSHRSIKSSVSKRRSGALSPSPLSPTGGESQENLVTESRNAGEDGSGSVVATVDGMSVEGDKTEDDDDDDRKAVKLSSQLPSIEVSNGLLNNTATIARKHAFRRLDSTKKSMRPESTAETVATDILNPSVMDETVGARTARNSAVETTAGNNKPKDLPAESQDVIGTPKRVPSAAPSTDSTPNSLTKDRLPSSLSRVAKSYRTNEWAKHLALADAPEPEELKVDVPPNPAEATVDEETAAPVDVQGLQQTAVTAALPPAVMPMPSAPSEPTPMPRSNSRVSVNSGMTTAQDPSLRPSHSFKRSSFNQAHRMSADVVMRQPIPEEETGGELHASPQSASPVGSARISPVSSRRVSMEQTGEARPPVAGVVSYSSPQTLLGMREVLLRSRSQVDMVPEIAGYPVQATSDAEPTRQSPPKEKLMRQQSLQYAASPIEAKQNPMQATVRGASRLSSAPAEAVPFDSHQPQRYSTLPSQAAREAKMQNFRQSVAQDLRAGTPIIPSGTNGTNGSQTLLASASQNPLVLGAGTLNRDGAARQSIDQGRFKLLSQKEQEAQRKQISLWEKERTDRLFEERMRRGDLMDAHRDALRRMQSSVRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0Q3</accession>
    <name>A0ABR1X0Q3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671818.1">
        <property type="nucleotide sequence ID" value="XM_066808200.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041260"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045582">
        <property type="entry name" value="Trehalase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF0">
        <property type="entry name" value="GLUCAN 1,4-ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19291">
        <property type="entry name" value="TREH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trehalase-like N-terminal" evidence="2">
        <location>
            <begin position="19"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="GH15-like" evidence="1">
        <location>
            <begin position="301"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="688" mass="78243" checksum="05AE83D7E2A871ED" modified="2025-10-08" version="1">MSNASCNVLGHACQRSADYLPIENYGIIGNMRTCALVAMDGSIVANHSRTLRLDFMCWPDFDSPSLFCRLLDKGKGGYFSIAPRDASSCTTKQQYLPSSGILQTRYIHEDGVVDLVDFFPRPKTTAILSSKTFKQNAYRETQKVQEELKRWLVRRVECIRGRLDLDIHIFPAFGYAKEPHETVILRPVVKSEDHSSKTVTFSSPSLKLQLDVTIDRGENESDVCPSVIFKKEARPGMTGEGVVAKILLTEGQAVSFILREDMAHHVTENITTAVVDKQQNDTQSFWFNWLSKSTYKGGWREVISRSLMILKMLTYEPTGAIVAAPTFSIPEDIGGGRNWDYRFSWVRDSSFTIYILLRLGFTEEADAYMEFMNQRFVHSLKPDGGLPIMFTIRGETEIPEVELDHLEGYKGSRPVRIGNGAAFHHQHDIYGELMDGIYLYNKYGKPITWDTWVSVRKMLDHVLTVMDQPDMSIWEVRNHKQHFVYSKIMMWVAFDRGLRLSEKRCLPCPNRPKWLEARDALYEEVMEKGYNKEMGCFIQGYENRTHIDSCILIAPLVFFIAPNDPPVHWNPGPDTPAAGKGGLTSTGLVYRYDTELSEDGVGGREGAFSMCTFWLVEAMTRASVYEPKYLARAINLFENMLSFSNHLSMFSEEIARSGEQLGNTPQAFSHLALISAAFNLDRVRENKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1H1</accession>
    <name>A0ABR1X1H1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672086.1">
        <property type="nucleotide sequence ID" value="XM_066808468.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041528"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045044049" description="Secreted protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="18862" checksum="9C2D9E0A7172AC7F" modified="2025-10-08" version="1">MKRKQLSFPILRFAAAAFVAASTTVHAGTAASDGGVEAPNNNTGVANPSTQKNAVPVTSVIPKNMSSPVQPDSSPRTLEDQSSQPRDRRPEVSQGAHAESEPEESEDDGLWENESGIVYGGFGWKHDKRGGEGGGGGGGGSRGSGGYGGPGGIVVLPPPFLHGGHYPKTSGGASRPRPFGFLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1T4</accession>
    <name>A0ABR1X1T4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004312</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672245.1">
        <property type="nucleotide sequence ID" value="XM_066808627.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041687"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="WSC" evidence="8">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="8">
        <location>
            <begin position="87"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="179"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="183"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="246" mass="26097" checksum="EFA3094530F7ED8C" modified="2025-10-08" version="1">MTIEKCLAFCAGARLPLAGLEYGRECYCGTSLAPPSVLGSPDTCRMRCAGNKDQVCGGPGQLSVFRNNTIVAATAPQKVAGNKDGAVFEYQGCHDESQGRVLPDAMFGNDTLTVEKCVAFCEGKGHGLAGVEYGRECWCRKVLRESTAKLDEGRCGMSCGGDGSQLCGGSRAIGIYRKSGGKNQRDVSHEGEADVAIKGRGERDGHEDNGNTDGALKRESSPPLPTVVKTVRLVRRGRWGGRRGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X287</accession>
    <name>A0ABR1X287_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein phosphatase PP2A regulatory subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004496</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672429.1">
        <property type="nucleotide sequence ID" value="XM_066808811.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041871"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000009">
        <property type="entry name" value="PP2A_PR55"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018067">
        <property type="entry name" value="PP2A_PR55_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11871">
        <property type="entry name" value="PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037309">
        <property type="entry name" value="PP2A_PR55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00600">
        <property type="entry name" value="PP2APR55"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01024">
        <property type="entry name" value="PR55_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01025">
        <property type="entry name" value="PR55_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="404"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU331113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="474" mass="53497" checksum="EFF0E830FCF6D264" modified="2025-10-08" version="1">MALDEQGPTWKFTQCFGDKGDVEDITEEFDHTGNYLATGDKGGRVVLFERNETKKTCEYKFHTEFQSHEPEFDYLKSLEIEEKINKIKWCRRQNASHYLLSTNDKTIKLWKVFEKSLKVVAENNLSHDLTPGNALGAGGGAPRASPGLTHFKNAEDLKLPRLTHHDTVVAAVPRRTYANAHAYHINSISVNSDGETFISSDDLRINLWNLNIQDQSFNIVDIKPANMEELTEVITAAEFHPTSCNWFMYASSKGTIKLADMRESALCDQHAKLFEQEEDPSSRSFFSEIISSISDVRFSHDGRYILSRDYLTVKIWDVNMERQPVKTIPIHEHLRPRLCDTYENDSIFDKFEVVFSGDAKNVMTGSYNNNFMIYPSDPEKETEVVLQADKSAFKAKKVGVATPINSSTSPTANGGKKNGSRAGSPAGAQGQRMRKETDADQIDFNKKILHMSWHPFEDSIAIAATNNLFVFSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2H6</accession>
    <name>A0ABR1X2H6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672446.1">
        <property type="nucleotide sequence ID" value="XM_066808828.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041888"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23157">
        <property type="entry name" value="Prefoldin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011599">
        <property type="entry name" value="PFD_alpha_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00293">
        <property type="entry name" value="prefoldin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674:SF2">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17377" checksum="176DD240394F3921" modified="2025-10-08" version="1">MSGQAGGGEAVNLDTLSVQQLSQVKKQLDEELEHLTTSFTQLHAAQSKFRDCLRCVQQQDGKSSALQEGKQVLVPLTNSLYVKGSLSSASHVIVDVGTGFYVEKDVKSAAKFYEDKTNEIGANVKDLDSIIQGKTNNVRVIEEVLRQKMAAAPQQQAPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X373</accession>
    <name>A0ABR1X373_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004831</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672764.1">
        <property type="nucleotide sequence ID" value="XM_066809146.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042206"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347:SF3">
        <property type="entry name" value="ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="3">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="74"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="267" mass="29493" checksum="382E63313B24806C" modified="2025-10-08" version="1">MNHPQDEVQRHSLEDPESFWAHQADQLHWHRKPSAVLTRTTKMLKGNTQHPHWQWFQDGQISTCYNCVDRHVRAGRGDQPAILYDSPVTGTKQTLTYAQLLDEVEVLAGVLRDECGVRRGDVVLVYMPMIPAAAVAMLAIGRLGALHAVVFGGFAAKSLAQRIEASRPVAVLTASCGIDGNKAPQSYQPLIRGAVALSRHKPGRVLVWQREQLRWDGLDKTAGERNWFKLVRSARARGVGPGACPSMLMTGSILSILAVRRGRPRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X376</accession>
    <name>A0ABR1X376_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI anchored serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672730.1">
        <property type="nucleotide sequence ID" value="XM_066809112.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042172"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045992623" description="GPI anchored serine-rich protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="20649" checksum="75A2C710C151190F" modified="2025-10-08" version="1">MHAPSFVVLAAGAMSASAAYMVEEPHSTTTSTSTLTHLVTITKCNPTNTLCPLYTPTTTPSSVVVSTTSSTTSSTPTPTTSSTSSSYPVFTPPPAPPAPVSSSSSAVVSSSSSSPVPVYSVKSFPALNSTTPAAFPTAYYNTTTPKSTMASPTPATLTSVAAVPSEPAGGNNGGSGYPTAPAPSPVPTGGAASLQAGLMMVMGAVAALVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X388</accession>
    <name>A0ABR1X388_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672780.1">
        <property type="nucleotide sequence ID" value="XM_066809162.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042222"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="231" mass="24572" checksum="A31E83D75BF47EAB" modified="2025-10-08" version="1">MPSRAPQQAPPASTEAVYHDDDPPPPYTVLEESETAALLDGRAGGGNGTPVEDYGVARRGAPRRRLLPLSNLMTIFLACILGTFLATCPIPRQSVPQLPRLALMTLCTSLVTLFSPAGGRTTKKPIVARRLIVAYLGLYLAAYALFGLAEEVGFETSSVGAVVFGHRTAAVGLQPGYGARALMVAVGFALQRASGLFSTCRILATYLLLMAWVYADAPLTILSLATGRKHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3B0</accession>
    <name>A0ABR1X3B0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672798.1">
        <property type="nucleotide sequence ID" value="XM_066809180.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042240"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="35529" checksum="E9AB0A6D0D728C0F" modified="2025-10-08" version="1">MDITSVIDCSRRADLPEPDTAVRCFLEHLELCSSHGILLLLCANPKIPKTLLDSSVPVLHMPIRFGPQVSSCYLSNLSATGGGFETAGDWPYAGRPEQVGSLVDGGMERMNARMQASIGWNAGRAVAQGVVFVPLATMRSTSPSVCMSEATLEFSAWNAARPGRWAGDDWLTRVSSYGPGMATFAVCTRRPLQFSPEHRSPPVASHSLTVVDSLSLTLIQSVALPPATLVLVLLVAAGLPLYCGTVEEPRETERETERESSLPAPQHLHLHSTFNFLSLACHTVPARNATQRNAKQSSPKQTSPAPLPKATRHSLFTPKIFGPWPPAFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3N2</accession>
    <name>A0ABR1X3N2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004974</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672907.1">
        <property type="nucleotide sequence ID" value="XM_066809289.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042349"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="67" mass="7767" checksum="2855B00906F3B73C" modified="2025-10-08" version="1">MVQYLSDTIPGLYDEYRQKAEELWGDGLYPYEAYGFSAPVRQFLYSYDVRAEIEEGMRQADGSLENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4M5</accession>
    <name>A0ABR1X4M5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673269.1">
        <property type="nucleotide sequence ID" value="XM_066809651.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042711"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="403"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="431"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="57829" checksum="6446C90C7D186D7B" modified="2025-10-08" version="1">MKEHDKDIENYIQHTLYIGDGQSSKQVRADLLCKASGVFMWVVLAVPILNKAFDAGGKHTLQHRLRQIPGDLHDLFRDMLTRDEHDRSELLSCIQWVLFAKEPLTPRRLYFAIISAVDPGSLTQCHSDEITDDDVKRFVLDKSKGLTELNTSLKIQFIHESVRDFLLKYNGLTEIWPDSLVNIEGQSHEVLKQACLAYISSDPVSLLRFPHPLPDASSPRGGDIILQLYHETPFLKYAVSNIMLHANEAKTKGFRQTQFLGTFPFDRWVTYHNLYQDYSGHQFSPASSGRSCFEPESEAFLTPIFAALACECLDAVEALFEQQLSMRTADSSLPNLPPLEVSDYRPVMRYYNGLSADDYSFDVYTPTGVVYYMVEAGDEISLAVYRATEQYDFKSLARSGFFLSFAAERGHNNMVKFLIEHGADISALDPVGWTPLLIALNLGHVDVAMTLIENGADVNTTNRGRSPLAVAISKEYHGVVALLIQRGAQRGSILLPDSDRKKKSPAWEPTTFPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7U0</accession>
    <name>A0ABR1X7U0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lytic polysaccharide monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673523.1">
        <property type="nucleotide sequence ID" value="XM_066806227.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039287"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF2">
        <property type="entry name" value="LYTIC POLYSACCHARIDE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="34299" checksum="26D93098333CE318" modified="2025-10-08" version="1">MVIGEPQKLSFKGKAVHGGGSCQLALTKGWDPKKDSPWSVIHSIEGGCPARNQKGNLEGDNSDVYEFKIPAGIASGQYTFAWTWHARIGGQPEMYMNCALLDVKAANTKRMELSARRELSAMSKRADFPELFMANIGPVGGGCTTSEALNQQIPIAYPDPGSSVDRPEGDKLFKQPCDGNPRAKKGSGGGSSGSPAPAPAPAPAPAPAPAEPSSPPASSAPQPKPSTPSAAKPTSSAKPTSSAAPIPTTSAVSPAPAAPSSAAPIPSGPNAPGSGAGGQNPSSPCTHGQFGCFADGKEGYVCTGTKWVKIFDVPSSDPPRKCTPGVGNGENMVLVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8G5</accession>
    <name>A0ABR1X8G5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673723.1">
        <property type="nucleotide sequence ID" value="XM_066806427.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039487"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058925">
        <property type="entry name" value="zf-C2H2_AcuF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391:SF7">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26082">
        <property type="entry name" value="zf-C2H2_AcuF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="307"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="424"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="440"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="511" mass="57438" checksum="710FF3B4D606537B" modified="2025-10-08" version="1">MQTIGGLVRDCLESFDSVLSSRTGHEKKADESLALARINDEQGKFKVWSGNIGAHRKGTSSLDYRLRDASNLRKEVQALLEDLLEALADAKRIFDGEVQPWDEDEPDGFLPDNHDEQQETEMDGFDFETELEQLLADIDETINYLYKVSAGLRSTPQHDRLMSSLAINTSLLRGIRHPTPQRLGKAISMRRHYFKYRESHRGKLGSGLEAGDRAGDGKSTIASSLPDVLKKAELVYGKLNVDDHSESGFTQTSFATSVADSTKLHVPPLPKEAATQEYFECPLCFMILSARTGRAWKRHVYADLRPYVCLYQDCPTPSQVFARRRQWVEHLRQQHWRMWQCSFDNSDPFQTPEAFMAHVRHKHHDAIGPDQIETFLTACERPCFDFVKQHCQFCNEALLSTHQYQRHIGHHLEQLALFALPTDHEAENEDGSESISNADSIDEDNDDAGISDLGDTDDDDDAEGKGEGQAQGSQETDLNASSNLSTGSSRDGSNEMQEESGVHLELNPLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8M0</accession>
    <name>A0ABR1X8M0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_002185</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673796.1">
        <property type="nucleotide sequence ID" value="XM_066806500.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039560"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048685">
        <property type="entry name" value="COG3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048320">
        <property type="entry name" value="COG3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007265">
        <property type="entry name" value="COG_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302:SF8">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20671">
        <property type="entry name" value="COG3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04136">
        <property type="entry name" value="COG3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 N-terminal" evidence="10">
        <location>
            <begin position="140"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 C-terminal" evidence="11">
        <location>
            <begin position="304"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="88"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8091824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="769" mass="85929" checksum="7220228C238D9CE1" modified="2025-10-08" version="1">MYEDSWYSFVPEVPQKKAPSSGHGTSHKRRESLLQQPNGANANEPIQPLGDLIEEAAPSNDPPEPTLIRRAKSYSDFYHVVRAQLSKDAAKKRRRKRRDRSLEASMVDKPEDDLPSRATPPDVSSTDQLLQASQQEFSVYRDQLAMTERHLDTLIDDTNGALKLLETLASSFHAVETQTSSFQAQCDDLLSEERRLQKLADEVGTDLHYYAYLDGVTRRLNAPGASRLVDHQNFAEILTNTDACITFMAQHPTYRDAESYLARYQSSLTKALHLLESGFTNHLEKISSEISKQIVSTNSEAARHALAYGRFEELVLEADGLISNVQKVICSCYDQFGYPIAGQNFDYYSNTAVNIFASYSDVRDRDLKPITQHDMEVFKKEAKDINVETASRNFVKQCYERSFDENALFTKVFSVEPHFSTDGNSAYAALKAHQKALVNAANVTPIATTIQSALQSAELPTICNLLGWITNEYLLLEYDEEESRYVIHCQELTARLLMEHLWPFTDTAFENEITKSISKHVIAPESLKITPVVNGVVTSNAHPIAKRALELLSMYDEAMPKERSQKSSPVIFRIVHETILALQRAETRLKANKTPNPDPDPDLFMIKNLLILKNELVSLEIGDIRSQADAMQHFGQIWDTLSPQNWMGLFRGILGGTLSLGGWLTPATKPAAAATTNGNQNQVQDASEKLDELLRQSIYAFTQRWGGFIHAAQSGKRSARSLGDVEKELDERLLTAFGGQPEVVAKLKEAIDINAEAQKELGGAKGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAH9</accession>
    <name>A0ABR1XAH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674395.1">
        <property type="nucleotide sequence ID" value="XM_066804622.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037682"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045365978" evidence="2">
        <location>
            <begin position="25"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="102" mass="11079" checksum="175A8AD33CB4938E" modified="2025-10-08" version="1">MARYSFQNTLAFCLLVVWSRPALAADSNPSVDMIVGLSVAAGVTIGVLVILCFLAQCAPALCCGLGRKDESWFNGHNDNMKEFATPPPIIEKPEPIVHPMYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB60</accession>
    <name>A0ABR1XB60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674659.1">
        <property type="nucleotide sequence ID" value="XM_066804886.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037946"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025533">
        <property type="entry name" value="DUF4419"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31252">
        <property type="entry name" value="DUF4419 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31252:SF11">
        <property type="entry name" value="DUF4419 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14388">
        <property type="entry name" value="DUF4419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="365" mass="40701" checksum="F8C0E70933652A9D" modified="2025-10-08" version="1">MPVTIRPSSHRAEPIHSHIEEDEFATTPNQILTGADHGYKSDEDRGDILASSFGPSDDKLNQLPEGEMVIASKNGLITAAAEAYSKHHHLVIRPEDIWIAITTQLRFYIKGHAEELRHLMVPHEGRKELEVKVGSLEQARDVPYVVQQFEGLLEKNVLDPSLVQWFLPDFSTTTPDDVTVASIVAMGAYSAYFSFWIDAVCGIPSVTLLGEHADYEKILHRLDRLCEFGEEPTQFCAQLRPILRRCVRSFDAPEDDAIKEFWNNICTIHAMGCGGTEHYYTSWITAFCFWQARGEKTTYHSLVPVGLRCMGVPVAKMILLAGSVAMGCSKSGEVTTSGHEALDTLQPQLGFMYEKKGASLDKDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB95</accession>
    <name>A0ABR1XB95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674711.1">
        <property type="nucleotide sequence ID" value="XM_066804938.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037998"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045830539" evidence="2">
        <location>
            <begin position="31"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="244" mass="24289" checksum="930E3FD72E5B3C88" modified="2025-10-08" version="1">MNSSGIGATLGCRVLLLRVVHLFEPSNGSAVEDVYILEAVGVDTSEAACPRIFGANLGRDNVALGEDGLSKTLHGLEQGFLGGAGVESMGDLVPRHIESCLAALVEHVEKQLLIHAIPCHLVLDRTLLGSGLSLGLLRLGVGWSLALAGGSALAPLALGGGRRRGGIRAVLILGSAVFVVVGGFGKDGVALSLASLVCGSGVASVGRRSGALLGAGGCKLGLAGVAAGGALSRCHGDYSSHTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBD9</accession>
    <name>A0ABR1XBD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000587</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674675.1">
        <property type="nucleotide sequence ID" value="XM_066804902.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037962"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF8">
        <property type="entry name" value="HECT-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="798"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="221"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="532"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1047"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1078"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1121" mass="125519" checksum="685D61D0561C6A56" modified="2025-10-08" version="1">MSMSAAAIPHRGPSSPQRRNGTTSRAPMPMPNSRPNAAPGLDILYRGPPPVPIVDSSSEEDDDFLGAKPKTSKPSNRSRTAPSHSRSMSHPFPSLFSSKKKKAPIGFDESTDDDYTPLKPPGMTSGPSMASTSTTARKPQRGPIDFRNGNCMTCGGLVRWPKELDVFRCTICLTINDLKPLEHSNGDAAKPTIAPTIPSLEHTRHLVQESLRLSVRHYTDSAGRISPGNWPRRSSSRGSDDYFSQMPLRERHQRSGSRGTPPPIYVRTPVFDEFPDENTEANPRGQNGDANRVLSTSFPEQRSAGFPMRSPPSPPNPLDAKYIFRPLEEYLMACFRSHNHFNAAFVARRQSFSSSRPVPFKIPRKPLPDTQRAKVAVAEDPVVTEQLDPRMLLLGNFAENGMWWTGNQQDAPPTKAQAVRKDDAHSLVTSRTPRIDWGLVMEWYHTIINAAEGWTAVYDELVQKDPSKALPDAERSRYEAIVLDAQEHIQRILLKCTENLLKRPGRVLKDPEDLRFLLLILANPLLQSGHKSFSGTFPQTAREKTGPTTGQRESAAGRHSGIIKRILGLLSNTPEPCQHHLVTWFSKLPEHLFLQFKDLVGDTKKREPKIDVTAGLIPQMSNSRMNNTPATLHAAIEATNASRKQKKPPEPPKRLPYVDDWQIKAASKVMALIFAANNLTHVRRNEVSTRHAHGHLLATSDFYNSLLDCMDFKADFEEWEARKGKFAFCQYPFFLSIWAKIQILEFDAKRQMAGKAREAFFDSILSHRSYTQYLFLSVRRDCLVEDSLKQVSEVVGSGSEDIKKGLRIDFRGEEGIDAGGLRKEWFLLLVREIFNPDHGLFVFDEDSQYCYFNPHTFETSDQYFLVGVLLGLAIYNSTILDIALPPFAFRKLLAAAPQSTASNTAFHQRSMMTYTLDELAEYRPRLARGLRQLLEFEGDVQSTFCLDFVIDVEKYGDRVRVPLCPGGETKMVTNSNRREYVDLYVRYLLDTSVSRQFEPFKRGFFTVCGGNALSLFRPEEIELLVRGSDEPLDITALRAVATYSSWNGSDQAAPEPEGSRRSNGSGRASALRLPKTSAGLSLSSREATGSRPPVPPLSSLKFPASDPTQDDTPRRALVSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD33</accession>
    <name>A0ABR1XD33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675277.1">
        <property type="nucleotide sequence ID" value="XM_066805504.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038564"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="47277" checksum="A56F500D549D87F1" modified="2025-10-08" version="1">MSAPHRGLPLPAAMTIAQTAPPPGPGHPQAPGPSLHSQGPPPPAQSQMLGTLPAPPQWQGQGPGADESMRSWLMAKTEEERRRQEEEKTRQETLRLEQRRLEHDMLRTSLDRGIPPPMVPVVFAGMSGGVLPQAALEWAQQYLVPQHSQPQQLLPAQGQISPEHRRDSQSHQYVPYAGSVGVPSTPGSGPGPQGGFVPYQGPGSPTRPRAHTMSMVGGPGGRSLGGSLPRLATGEAMGGPSGVPSHATHSLAQQQAAPQQQETQSPSIYFHHWQPPTSQAGSNQPATPSVDSPRKRKATGPPPPAAQGPGAQMRYRSPPFSQSGGPSTLGNPPPGRRRGHSRQRSDISAYRSTRGRGDSFGPGRAMSPGLGTPREGGAAEGSSMQPRGTHSVSSLLSDQPSPRYAMSDMRNHPPGEERRQSPVSSEERPRGGAAGSASLRDGDREHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD44</accession>
    <name>A0ABR1XD44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell polarity protein alp11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001203</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TBCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675291.1">
        <property type="nucleotide sequence ID" value="XM_066805518.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038578"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01789">
        <property type="entry name" value="Ubl_TBCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045172">
        <property type="entry name" value="TBCB_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF85">
        <property type="entry name" value="TUBULIN-FOLDING COFACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14560">
        <property type="entry name" value="Ubiquitin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="5">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="CAP-Gly" evidence="6">
        <location>
            <begin position="176"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="241" mass="26625" checksum="DCDF9608D6947150" modified="2025-10-08" version="1">MADVPLQVVSENSASERRITPSWSISQLKAKLEPMTGVPPSAQRLVLKTPAKETVAIEAMDEDNTYLSSFPLTPYAELQVVDTRPAGQRPNYTDTSGVDKYVMPADEYEKKTDSVLAWKKAEKLGRFNPDAPSLEQAKIDAFLQEIKSRGIEVGKRCRVGGEDAKRGEIKYVGDVKEIPGALGAWVGIQLDEPVGKNDGSIGGTRYWGQESGMKHGVFVRPERVEVGDWPMLDDLEDMEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD77</accession>
    <name>A0ABR1XD77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675322.1">
        <property type="nucleotide sequence ID" value="XM_066805549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038609"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="198"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="247"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="304" mass="32355" checksum="46241E6DAC4204FB" modified="2025-10-08" version="1">MELYASGNNAWNQLVFGGVESASNEPTDFASFQLVLRDPVIERPHASLACTCVNTSNGIQTAGFPEDWMQSQSLKDRVLQSLAAIAGNGTIAVYDGQAVRQYQSVSHFQHGTAQRVFTSMRNVSQIVAYETGFAALSTTGQVWTWGDERYEACLCRDVSDVSLAEEPGTVAELEGLPTGKVKKLAAAGYLLMALTEGNDLYAWGGRPGLPGFLDDISASPSPVVIEDHDVADCAIGQSHAVVLTMSGEVYTAGANGNGQLGITTETDSPWSRVPFSPGSDATILSVACGPRNSFMIVQKPSRHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD84</accession>
    <name>A0ABR1XD84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_001332</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675420.1">
        <property type="nucleotide sequence ID" value="XM_066805647.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038707"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="entry name" value="ATP synthase (C/AC39) subunit, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="entry name" value="V-type ATP synthase subunit C domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_csu/dsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016727">
        <property type="entry name" value="ATPase_V0-cplx_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_csu/dsu_dom_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11028">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018497">
        <property type="entry name" value="V-ATP_synth_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="V-type ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR018497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="366" mass="40945" checksum="7608671AD8FC6B0D" modified="2025-10-08" version="1">MEGLFFNVNNGYTEGIVRGYRNGLLTSANYSNLTQCETIDDLKLQLGPAYGDFLGSLAPNPSTSALAAKTTDKLVSEFRYVRANATGSLGKFMDYVTYGYMIDNVALLITGTLHERDTRELLERCHPLGWFETMPVLCVATNIEELYNSVLIETPLAPYFKGSLSHQDLDELNIEIVRNTLYKNYLEDFYQFVNSHPEMAGTPTAEVMSEILEFEADRRAINITLNSLGTELNKGDRKKLYPSFGKLYPEGTLMLSRADDFEGVRLAVDGVSDYKSFFDAAGLGGGPSGPGNMAGGSGGNDSRSLEDMFYEKEMQISKNAFTRQFTFAIVYAWVKLREQEIRNITWIAECIAQNQKERIGNYISVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDL6</accession>
    <name>A0ABR1XDL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675539.1">
        <property type="nucleotide sequence ID" value="XM_066805766.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038826"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="238" mass="27921" checksum="28A8BA2CC4060B34" modified="2025-10-08" version="1">MIWEWVVEQPHAVETRGFYDHSKKLWKTHGKGMALSVYPRFPPVHDVCHESRRAFLESSDFVPDTTGLGVAWHPERDALKCHNIEDRWDSDLNYDWSWWDDIRYSSYYTSWPPGLLGRNDVQNLQFSLSQFHDIFPIGAANDGRHMYRDWSEMQGEILQRFPNAKTVELVAGEEFQSSSGEPRSFEVTMSFPCGPVNFIRAWDILMGLRDSEYQEFSLKIVGKMVCRIKKETFNGRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDL7</accession>
    <name>A0ABR1XDL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Pectate lyase</fullName>
            <ecNumber evidence="4 9">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_001369</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="4 9"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675457.1">
        <property type="nucleotide sequence ID" value="XM_066805684.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038744"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8094684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="211" mass="22505" checksum="97B468386628E156" modified="2025-10-08" version="1">MLQARDVTNKQTFLRNTPSVSHAVAAANGGGATQTGLTTTLSKSSGAVSTSTPIVIAAACQGKTETDERESMFILKNGAILPNVIASQAEVVHGQEICWIRQEKKIGRQRNIGRLGDQVVQDPADDLERQARDGAAEDGPEEQDREPEELGQRGRRELVQQLLRDGDALLPGVERRDAAAAVAAVMVSAVEGRPLDHDLAAGRHRGDTVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTC0</accession>
    <name>A0ABR1UTC0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660741.1">
        <property type="nucleotide sequence ID" value="XM_066818553.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051613"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="126" mass="14302" checksum="0A05A84062A657DD" modified="2025-10-08" version="1">MSGTTKEAPSTPTINKTCLPPENSASAPSTPWSFVTWFFRTPVQEWLDGLPKDAEGFEDLVWADDNNDGRPPADSDLLDFIVDDYWVYIGTRADLREKQRQREALLRKPEKKEAKRETDVMGHSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTQ4</accession>
    <name>A0ABR1UTQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014374</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660876.1">
        <property type="nucleotide sequence ID" value="XM_066818688.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051748"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="432" mass="45919" checksum="97C0046ACC811A98" modified="2025-10-08" version="1">MFGALRYNSVTKDVEHVELERADGFEARGYSRTACNECRLRKLKCSGDRNGCKRCRAICITCAYQPSSDNKSTFKVSRPSPSADNVDMATRSNAASASPGPQPRQQRAGGQGQQRANPGDKTLDHTSSGSGPHPNNGPSAAPDTPMELLYPLSPPPSNLDWDFSSADFEHMTDLDGTSSTAGDAPALSALVAAHEDLPQGMNVESGGDDYDIPDASVDLNPTTSHAASGGQYSMAITSKHHQHTASSPSFFAPSSKQGSKSQSWESFVDAAAPLLDPPPNAPASLDDILASLTRGMNVVEQVLRCGQCNAGTENRMLLATIAQQLALIGGETVASARRGWKTPVILRREDYAFGRVSSIGHAQQQRPGLQFFDHSITRKGHFPRSLQGGQSRDAIRDVVSRITLAHRATTRGSASGEGQDGFQCQGPEAIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVN8</accession>
    <name>A0ABR1UVN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661592.1">
        <property type="nucleotide sequence ID" value="XM_066819404.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052464"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF1">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="1">
        <location>
            <begin position="5"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="459" mass="52849" checksum="0F74881D965A77C3" modified="2025-10-08" version="1">MSKAKLIICCDGTACSEYLGDKKSPITNVSRIARAIKKWDEECRQIVLYLSGIGTDEGNWLNFKNQAIGQGLESLILEGYMFLSHNWTQQDEIILIGFSRGAFAMRCLADFVIQRGLLSKQALHTLPDEFRHWIKTGHENRERSGMKIKVCALWDTVASMGSSFAPENQLGRFSFVHSELLEDIEYAFQALSLHERRSHFAPLVWKYRDVDDRVRDNTLDQCWFAGHHGDIGGEGQALSHFALAWIIAKLRPFVAISEDEVWTRQPLLDAWQIHPGEPLGILDASRTFLCRAFQKLHRQPCCHFQNENGQDHLAERIQHDGSRERMHFSAGLLQHYGAVERFISFHDFDYFDPSVERGEDFRALQPNDRRSWILAYPGQANPHARKLFRFLYKDPTLQPIEDPAYYRVEEQTLGEDEKHVLAAWTQHQHGLLIDEMSAIGSPELKNTYLFTLRSYLSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVY3</accession>
    <name>A0ABR1UVY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_015170</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661672.1">
        <property type="nucleotide sequence ID" value="XM_066819484.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052544"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF18">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 15" id="KW-0732">Signal</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047246733" description="Extracellular membrane protein CFEM domain-containing protein" evidence="15">
        <location>
            <begin position="22"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="203"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="16">
        <location>
            <begin position="34"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="17">
        <location>
            <begin position="110"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8063073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="20">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31179" checksum="B1857C15927C46A6" modified="2025-10-08" version="1">MWHGRGYILILATLIFSSCQASLIEYTKEIPKSIPASVCQTFTNETCICTDPGLLEAVTECASKSCEVLDQLKFAKIQEVACDKPQRIRSMVDEIGFSILDVVTLACILVRVFVRYHLTTTMEMDDWVVMAMVMVWAVFLGLGHYIRIVALGRDIWNVDPQTVTAVLRATFIDELFYTLVLSLCRVAVVMFLLRVFNLPRFRCLAWAVIGWIVLYAVGVITATVFQCIPLDFNWLGWTGQYPRQYKCIDVNALSFAAAGIGIAQDLAILVLPCPSSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXD9</accession>
    <name>A0ABR1UXD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014591</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661093.1">
        <property type="nucleotide sequence ID" value="XM_066818905.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051965"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17870">
        <property type="entry name" value="GPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030230">
        <property type="entry name" value="Gpn1/Npa3/XAB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF8">
        <property type="entry name" value="GPN-LOOP GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="288"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="397" mass="43294" checksum="ED80D4ADAAEE1953" modified="2025-10-08" version="1">MAELASAAAAAPAPATGPKPTAIVCVGMAGSGKTTFMQRINAHLHGQKEPPYVINLDPAVLNVPFEANIDIRDSVNYKEVMKQYNLGPNGGILTSLNLFSTKVDQIVGLLEKRAAPSEANKAPIKNILVDTPGQIEVFVWSASGQILLESLASSFPTVIAYVIDTPRTASTSTFMSNMLYACSILYKTKLPMILVFNKADVKDPSFAKEWMTDYEAFQEALQEDESGNAFGGVEGEGGGSGYMSSLLNSMSLMLEEFYAHLSVVGVSSMTGQGVDDFFAAVKEKSEEFNRDYQPELERKRNEREENKRVAREKELDKMMKGMSMATGSSSTPGVKPPNDDDDLDVISDGEDVDDFADDDEMDREGLQARYEAAMQGEEESTMADASFAKYIHTQRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UY15</accession>
    <name>A0ABR1UY15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661272.1">
        <property type="nucleotide sequence ID" value="XM_066819084.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052144"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="30598" checksum="FEF21751D8973D0B" modified="2025-10-08" version="1">MIWKTALEVEASTRIVPVDYDAHVIPRKQLASPLLSTCRQSRWHALRFYPIKLPIYKFPKIYRDADHYSSLCGKPAGLRLRSCEYVEIQSAVRTGLRGIKSQGQAVGFVYLSPQHDTFLCGIDFTKYFLYNIPWTSEHTTPRTKAYVSALMGDADRHLVQNMVLAEILPHSPMPCAAAYALSCANILWGKSWFPSTKSWRHCWLPHRYDARRERERSWICRRCDAEDFFGYMGPTDGIEKLQVREWGWEYNRWNQCEIIRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYC7</accession>
    <name>A0ABR1UYC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase D/nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661650.1">
        <property type="nucleotide sequence ID" value="XM_066819462.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052522"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00138">
        <property type="entry name" value="PLDc_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248:SF11">
        <property type="entry name" value="PLD PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8063051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="508" mass="56959" checksum="C3658985E7D6C889" modified="2025-10-08" version="1">MTTALDAFAGPWRYHLDHNGDSKFRDTRKTQFPDYYHRRSPADQGADADTLLTTSQIHSFQLGTGASIYTQSILPAILQARREIIMVTCFWAQSDTLTALSNTIAQLAQERERFISSQPDTAIEPLRIRICFSSRSLFQKLFHPNSKDGFVYPPHTWPSQLGLPAPEALRAGAIDLQVKTLFFLPFSVMHPKFVIIDRERAWLPSCNVSWEPWLEGCVDLSGSAVSSLMRFYQCVWERDLPSLPADRNTSPRSPELAPSWLTAIQSPASRLAPLSMESVPTVLLPSSHHQNPCFRPFPWMDDPKPPLTPLNVAISCLLEMAQHAIYLQTPNLTSASVMDGILQALSRGVHVTIVTGKNMMLLEQIVTAGTTTSRCLKSLIRRYHNLKASSVMQPRRDDALATNLDIDLEAGRPRLGQLRIAYFRPDVDDQAKGVSEEPVQSHLKLTIVDEEYTVLGSGNMDRASWFTSQELGILFRSVQFANVVSSNVNDVLKTRTMSIYESSRARDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2A3</accession>
    <name>A0ABR1V2A3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012071</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662077.1">
        <property type="nucleotide sequence ID" value="XM_066816385.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049445"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF2">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="87"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="831"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="849"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="932" mass="101245" checksum="D1BB8DE827A461AB" modified="2025-10-08" version="1">MAADNEAVALPGPEAEAEAGAAAAPAPTAVTRSPEPQTQEPPSPTTTATQNPEEKDSAGLTPSKKRSASTSEPSGSTKVTKRRAARACVSCRARKVRCDVVEGAPCGNCRWDNVECVVQESRRRNTSAAGHTPGQQKIAEAQRPTTTSPVNISPAPDVRRQSEVSLAASAVNVTPAEAAAANAAISQQVAQSTCATSFPDGSGLDGHVPNLIYQQQSDARTDPVLLLAQLQQSTNNGPGFPNLWSDATAGFSNAKTAQFLNTLEEPDASSQLPGFIRPLPSKIAPEDVNYLHLKGALTLPTPSLQNALLRAYVEYVHPYMPLMELHDFLAAINSTDGLYGQISLFLYHAVMFASTAYVDVKYLKEAGYSSRKAARKAFFQKTRLLYDFDYESDRLILVQALLLMTYWYETPDDQKDTWHWMGVAISLAHTIGLHRNPANTNMSLRKQKLWKRIWWSCFMRDRLIALGMRRPTRIKDEDYDVPMLDEGDFEIGPLADEIQVVNHDCTLVRDVLMQQELASMCVAKAKLCLCISQMLKAQYSVLVRDKSRPENTTNSTMMLHPKKQLDNIELVNEVDISLMAWVQALPACCQYRPLTQLDLRDGHKTIAVQRNLLHMVYYTTISALHRPQFLHSSPLHVPTTSRQAQEMSRMKVRDSASHITRMVNELHQLKLEKFLPTTGVTVILPAMIIHLLEMKNNVAQARDKAVQGFLQCMKVMVKLRDSYAAADYAVAFLDAALRKAAIDLQASQQAAAAATTANAANAANVANAANAANNAKNNAAFFRAPTAVVVAEEMATPPPENLPYMTQPEAALMNPSTVYVPPAELMGAAAAGIAGNSPPDTNKDGFTPSASSGSSNGSDACQPPTLDVEMDFVDNDQDEFDWNALTGTNIDFDQWLHFPGENVGGAKGPTGTAADGGAADPFLNVLGDGVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2K7</accession>
    <name>A0ABR1V2K7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662179.1">
        <property type="nucleotide sequence ID" value="XM_066816487.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049547"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="117" mass="13034" checksum="FBE03C54EEFA686A" modified="2025-10-08" version="1">MDPNATARLATGSLSMGLYHYDLVMRRLSLLGIHCRLQMIMIFMNEQNCAPEDIDPEVLCVIAHLLADMGRAIDDIEACVAHDAREGAIATAGDEDHIRKVMSLFFDVREVIDDFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4D0</accession>
    <name>A0ABR1V4D0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012514</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662520.1">
        <property type="nucleotide sequence ID" value="XM_066816828.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049888"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF2">
        <property type="entry name" value="102 KBASES UNSTABLE REGION: FROM 1 TO 119443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="42"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="35156" checksum="C5B414F5345BBAA1" modified="2025-10-08" version="1">MPQAPVPTTVSLSALRAGHLTLPEHLFVTDADPERRNTVPSLAFLIRHAPSKTNLVFDLGVKRDLSGYAPAMAPHIAARQPAGAGADAEDDAAASLRRGGLDPATDVDFVVLSHVHWDHVGTPADFAAATFLVGSGTLEVLRNGAGPRYPAEIFRRDELPWDRTLELPPVPGRANGGAGGYYETHAPRHTPMPKGSLAKLPPRGPSSVIVDGRDGGASCAWKPLAGFPHTLDLYGDGSVYVVDSPAISTATSTCWCVRAMEFAEYPDNQGGVRSVHTDTEVARTTLDGIKRFVEAGIELEGRKFKVEVVVAHDAAWAESNRGRFWPGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4G3</accession>
    <name>A0ABR1V4G3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ntf2 and rrm domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012818</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662824.1">
        <property type="nucleotide sequence ID" value="XM_066817132.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050192"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039539">
        <property type="entry name" value="Ras_GTPase_bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693:SF20">
        <property type="entry name" value="AT27578P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="NTF2" evidence="3">
        <location>
            <begin position="33"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="158"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="284"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="473" mass="49819" checksum="302376F47711E09D" modified="2025-10-08" version="1">MATNGKSTCAGSTPDTSNVSTTGSNSNLGKDEVAWYFVEQYYTTLSKSPEKLHLFYSKRSQLVYGKEAEVSTVSVGRQEIQERIKSLDFKEDTKVRISNVDSQTSFDNIVIQVIGESSNKTGEDPKKFVQTFVLAQQPSGYFVLNDILRYVDDGAVEEEQAEEPVAAEEVPAEQSTSAAPETAEETAEPVAPEPAAGEPAPASSLDPAAVDQKLEEVSASGKDASVNGDAAADQSAAAAPAAETAEKAEASKPDPEALAKEVEAETTQEPEKPTDPSPTPPRPAAQAAAPAAQAAATTPAPAQTSEPAAAKESTEWQTAGGDNKRARPQSISAPRAEKEEPSKVESEDLRAALAAHGELVYFDINRQKSCAFVEFANPAGYNAAAAANPHVVNGESIVVEPRRPRPVPMAELTTATLAAVTQPTEEAVVAWTEAELEARDVATSVARTVAGVVCLVVVPAVLPRLPMPKILQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4L6</accession>
    <name>A0ABR1V4L6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662610.1">
        <property type="nucleotide sequence ID" value="XM_066816918.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049978"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="214" mass="23406" checksum="58C59834074ED249" modified="2025-10-08" version="1">MCDRTAVVTSLHETRNSMHPPPQHRQRRLRRTAASKPTSSSNHGSSSTPSPDSAERGIGGGASLGMNPYYSSSTWPNPNSSEGRRISTMQQQQARRMTKQQYHHLQQQQHEQRLGVSKATAAAAAYSAASANPGASATSRAPATSGTSVSSTISAPSPPERESDRMARELPSAKKELKEMDTHLRSMAQQQRMMIDDTLDQWTRLSESTCTVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4V4</accession>
    <name>A0ABR1V4V4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012973</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662979.1">
        <property type="nucleotide sequence ID" value="XM_066817287.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050347"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="13"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="298" mass="33280" checksum="D216578B173FF7E2" modified="2025-10-08" version="1">MVKDPEDVALRTSNLFTFFLQLAFTYSITLIKFAILAFYWRVFNTSSIRWPIIILAILSGVWLLARTFITIFHCVPVHAFWDETVEDATCLISDSEYIFWSTLAHFILDVVIIVLPAVEIRKLQQFSTKQKIGTCSLFGFGILVCAASLTVVVLAKEINSSSKDIPWNMANIMLWATVEVNLSVVSACLPLFRPVFITVRKNSIRMSGSDYGTYPPSRRHTSVSSFGNDATGSPIQPPAPLPSFYRNSKGWLRDRAAKAMGYESSVPNFSKPKSMHGCPYESNGQPGVPQFPQGANFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V535</accession>
    <name>A0ABR1V535_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED19</name>
        <name evidence="11" type="ORF">PG997_013060</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663066.1">
        <property type="nucleotide sequence ID" value="XM_066817374.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050434"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013942">
        <property type="entry name" value="Mediator_Med19_fun"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08633">
        <property type="entry name" value="Rox3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="244"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8066313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="332" mass="36200" checksum="C31BBB64DBF34F15" modified="2025-10-08" version="1">MATMSFNPQTPQSPSQLSPSTADPVSSMNSSMTSITTLPTPAHSVNGSIQHGDSAHDIAMSDADSPHKRKRMPDDMGEQGPKKTHLEDPRRLGIEDLHMDVGEKYFLCRTPHSASLPSVSEDLFEMFGLTGIAAEVARTKPNGEKNALRKTYKGHIKSLGVNGHFDKVEKDPYDQDGFMHMLLYPESEWYVHEVQGKEVERGFSDTVQSSLSRAMTMARGTLDNSIWDSSVLGDLAPSVVTKKPKEGLKKATPGTPIGSAGGLSNASKLQVPQVNRVRRIGKKRSYQDSSFEGYGEGFPDDDQGAASGYSTGEGDDRSSKLKRRKQVTTDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5V0</accession>
    <name>A0ABR1V5V0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663320.1">
        <property type="nucleotide sequence ID" value="XM_066817628.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050688"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="491" mass="55591" checksum="DF44783B40F1B45F" modified="2025-10-08" version="1">MATTFLSSSGPTELLVLVLRSCDSIADVLAFGDTCRYLRSVLRSNTSTILRDVGAGSVVCFDEALVAPTRNKVRAIQICIDAEHQEQLPPADLQLDDISAQPLSLEELPRILDLDHCVHALEVSIRHKDDFDLHENCLPESPEGMPEWSTRLRKAIYRSFVLGAALSRAYRDPFFDDTEKWRGMEEQDYSREDYRYLEGFAAYSMQPTPEAEHATFGPVADWLVGRILSDDAGRRAHSSAFEQKEGRAACCNDLIDPESWDSDADRPCPLPKRESCQHSDSHFIAWEVMQVLWVSCHIQSWPAYSRACCDTSPVDRSRHEEEGEPQDLDPDPQTYPRKAHVVLFGHFSPEELRIPGIILDDRKPKYDEPKILARPAVRKSAPSASGADDQQRVFYSEAGFDDFLGFLGSVERLQQRRQAKHGFRFRDGVFDDDDPGFEVRADFHEFLMRNAIVANNEECQNDACYAEGSGFLVGLDPLPELIHGTWYWGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V664</accession>
    <name>A0ABR1V664_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyltransferase family 28 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012467</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662473.1">
        <property type="nucleotide sequence ID" value="XM_066816781.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049841"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="2">
        <location>
            <begin position="160"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="311" mass="33134" checksum="D3A721858EF797BA" modified="2025-10-08" version="1">MSVLDAKRAAAAARSSSERESGNNDNDGQEQDGSANKNGPDVAVSDGFPEAAIPRPEAGMPLPELPQLGAEDEVPPAYSEVHDQISLHQSGFDAGATLTDDGRIDININQTSRQLADIIAPTLRDQLKQDARSEGPLPPAYIPLSLGGRPGQTPPPRLNIVIQIVGSRGDVQPFVALGQILKNTYGHRVRIATHGTFQKFVEENGLEFFCIGGDPAELMAFMVKHPGLMPGFDAVASGEVTKRRKGIEQIVYGCWRSCIEAGNGFGPAPRLQRGRNVPGEGATTMVMDPANQPFVADAIIANPPSFAHTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6C8</accession>
    <name>A0ABR1V6C8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_013482</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663488.1">
        <property type="nucleotide sequence ID" value="XM_066817796.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050856"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06546">
        <property type="entry name" value="GH18_CTS3_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF60">
        <property type="entry name" value="III CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="GH18" evidence="13">
        <location>
            <begin position="10"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="289"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8066735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="348" mass="38135" checksum="ED4228FCDE73BA0B" modified="2025-10-08" version="1">MASSLRAALPRIVIYHQTIHDPNGRHISILPLISQPGVAVTHIIVAALHINDDPNALTLNDHAPVDPRYITLWAELRIAQASGIKVLGMLGGAAKGSYTRLDQDQSSFEAYYAPVYNVIKERALDGIDLDVEEAMSLGGVIRLIDRLRADFGPDFLITLAPVAAALLDVRRNLSGFDYEALEVMRGSQIAWYNTQFYCGWGDASTPIMYEMIVARGWAPEKVVIGLVTNAENGAGFVPWELLRANLTLLKFQFRQFGGVMGWEYFNSSPGGKDKPWEWAQRMTTLLRPGEDAGFGEPAATEGGAQDKVADVPKTSSSDVQVADPDLGTSIDVPIPTDFEYFSDFSTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6Z2</accession>
    <name>A0ABR1V6Z2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663714.1">
        <property type="nucleotide sequence ID" value="XM_066818022.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051082"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="568" mass="64637" checksum="17EE8FEC511274DA" modified="2025-10-08" version="1">MNIVTQLNSPRWLDLMLQKHFTTELRAELDNDPGRLLDMIMDWANKWAGVRYRYVASYAETMPLQHLWGVRFHEKNKDKKEWKAQRKALMTGVNRGLIHAPDAEGDALLNLTNWWATEDNGLFDRTTEQAGQQAQDVRDWGYFLTYQTRRVREGLQEKRPRLHAYFVWIRDYINLCAFFQGMVADALNYASNRRVKNDDDGNRDIGDYVGFMRSIKQGVDDFLRPYRVFLRRVRAACIRAGLYNRDCSDLAANVNWATVRLSAADVADIREVVEAHNTACRAFDVASTRLEKRDDMYPDIEMMSTVFPGKLSEYPPNLGPTDTTNAQGELPWDFVAVRANEHLFAALTRHAGPEASLHAVRRLGRDGGHDGYDAAGALGSHFDTPTKQPPSPKTGGDVFTTAPAMKSRKAWGKEPEQLQQEGDVEMAGADDDDAEYQQQQQQQQQQQQQQQQQQQQQPSIELEELCHSIGELGKKAGVVESDEARYQRLARVQLTLQLMNLEVTEQAEALYKDLYVQDPPDTRYLLELESVWQTRSESSDDGHDDDDDGDGRDGGGDVVMEGTERLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7Z4</accession>
    <name>A0ABR1V7Z4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014049</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664055.1">
        <property type="nucleotide sequence ID" value="XM_066818363.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051423"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="181"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8067302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="66905" checksum="59EA48D3D6B180CD" modified="2025-10-08" version="1">MDVLLRTAAIRDRWQSDARNTTIVPRKPTPSPLSLVAPVRKLLQANSSLSALQTTVPPPWGKRSALARRQQAKQLTVVSSQAAELRNMSLTMAMGNLTTRRCWRAQCDGGRPKCTHCTTKRRACGYIADERESRKSRLDALEKFVDNLRDLPTEQAGQLLQGWRESRGRLDSVPKLVEAAKDAADTPSDSSNPSSSISPDSYTTQHVVPHATSTAGPNVPHKASSHISHPSNRSSIDSPWRQVLLWLPPPELTRRFVETFFSCSGKLFHVFSREQIDQCFEATFHSPNNGSLEYKADVCCLMTVAAIGAQYEHEVIDLEAQHTFYDVARHHLEAVIQARPLDAIKITTLFCLYNIMDKTTVAVAYVEIGLGTCRRYRLECKRPPQGDYPEEKWAEYRKAWRSLIFFFKSSDLIAMEASRPRDQHVDGPCGKYFYPLYHDMTDCVMLTPRTVVQNEMAKIALLKAKVMRMHLAFKELTPRSIQSIMDDLQTWYSRLPWQMRLENLMYSEHSASIRRSGFHVHLLYLGGMMLCYRRVAAQITQPMQQPREIPFPEGEMTLLLDHCEQAVVAAATSARILRLLLEDNGVFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7Z5</accession>
    <name>A0ABR1V7Z5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664073.1">
        <property type="nucleotide sequence ID" value="XM_066818381.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051441"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8067320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="172" mass="20540" checksum="03756CE506F34501" modified="2025-10-08" version="1">MPQLFDGVHFPSLRELPHNNGDPDCPYYDSITGKNRIHWCLLGQITEVHQPRRRLFAKDREGERFEVRFYPKYKHNNFEDDDSRLLEYFNVGNTLAMYYARNHQPDNIFHQYRITEALIIPLPMDKLLQMNNDYVEYGDAYGTKRKCHGCGVCKEKEDLWMCGSCKIFYYCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V944</accession>
    <name>A0ABR1V944_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663538.1">
        <property type="nucleotide sequence ID" value="XM_066817846.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050906"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="304" mass="32968" checksum="189440764DB292F4" modified="2025-10-08" version="1">MAPFASFSLTPEEKSSLQSDIDALIAEVQRTLSAIPHPSVHDHREALRILHEATTMSRDLQDENDDEDDESEEDGSAKAHRARALKQSLAEAAVLRGDILRALGRVPSARAAYTEAISQYPDDFPPADAHSALTSARPRRPSLIPPPLHLHLALPIPPPTAAKRAWTSLMELSSGEDAATSPATTPDNTARRNSTPSGNAAMSKRDKRRAGVWSAGYYETSSAPAPESNGEAVLKQHLEQQRQDAAADPAIQDVGARKMVCIVEQDEPASDSSASSARLSDHSIQHKKKCGDLRSMRSQARERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V985</accession>
    <name>A0ABR1V985_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663281.1">
        <property type="nucleotide sequence ID" value="XM_066817589.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050649"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053008">
        <property type="entry name" value="Phomopsin_biosynth_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="268" mass="29824" checksum="136AD5DADD321FFF" modified="2025-10-08" version="1">MAPNRHLEIQYQPFLKYAEFSDDPILVEASPRPQPEQPGLTKTPCCQRRILSMHIVSYIVVVITTSLFWVLVMLSHTSSNDAAAACASSSTIGGTGNTSPLAIPDKAQHRVNITTGATYLTCGNSTQEARSHGCQYDVLLNNWVPAPCYDADFVAEYEEDGSSAAYRDEALTQRIEPGGEALGELEFYYTSRRDHVNHCAVMWRKQFAQLFERRAAFDSVIADPFHTEHCSQYLLDAPERAVKGGEVVPTKTFVGFAGCWVRHEDKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGN7</accession>
    <name>A0ABR1VGN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sugar phosphate phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010611</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>beta-D-fructose 1-phosphate + H2O = D-fructose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:35603"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:138881"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>beta-D-fructose 6-phosphate = dihydroxyacetone + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:28002"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="domain">
        <text evidence="7">Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664216.1">
        <property type="nucleotide sequence ID" value="XM_066814926.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047986"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10880">
        <property type="entry name" value="Uncharacterised protein PF01937, DUF89, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036075">
        <property type="entry name" value="ARMT-1-like_metal-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039763">
        <property type="entry name" value="ARMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002791">
        <property type="entry name" value="ARMT1-like_metal-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12260">
        <property type="entry name" value="DAMAGE-CONTROL PHOSPHATASE ARMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12260:SF6">
        <property type="entry name" value="DAMAGE-CONTROL PHOSPHATASE ARMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01937">
        <property type="entry name" value="ARMT1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111321">
        <property type="entry name" value="AF1104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Damage-control phosphatase ARMT1-like metal-binding" evidence="8">
        <location>
            <begin position="24"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8070408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="485" mass="52945" checksum="7E96A942F7E236A6" modified="2025-10-08" version="1">MSRSATTSPAPYSTADPSSFGYETARKRWPTIVTGVVDDLTKAVFQHVHVKSKVDEGCAIIASIQDLKNEILAGAELCPLKDDGSAEIAAYNEELVASGTQTWHDSPWLFCECYLFKRISTYFSLSDHWKDYDAFMNQKMDTFRSSLPAVAELAAQYRGLATQQKDAAAAAPGSEEVLFREIFEVCLWGNATDLSLLTNLSYEDIQKLQGSEARKAAESNILVNDLPRVYDQLRRAQDAGKPSRVDIVLDNSGFELYVDLLLAGYLLSSGLAQEVVFHPKNIPWFVSDVTPADFEAVMGILADPARFFGDSSNFVGDLTFLSSQLEGFRKQGRLSLRTSSFWTLPCGFAALPRADPALFAELRASNLVVFKGDLNYRKLTGDRAWSPTTPFVEAITAPAPSGKSCEQSDAKAEDSSASSMADLNVLALRTCKADVVVGLAPGKDEELRSATDPEYAAAAAGSSLSGPRRWAWSGKWAVIQFSQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHP5</accession>
    <name>A0ABR1VHP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ring finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664526.1">
        <property type="nucleotide sequence ID" value="XM_066815236.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048296"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="114" mass="13098" checksum="C424C293F5739D3D" modified="2025-10-08" version="1">MFSSDMFRNIRDFFRTAEQQPTAHESEKEQAAAPQTRSCATSNHTIVRSKNKKQPKSCWFTTSPPCQFVVRLKQEFDSARTIRATTQKCPNPECKARIEKDGGCDVMKYICETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ09</accession>
    <name>A0ABR1VJ09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidoligase enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665027.1">
        <property type="nucleotide sequence ID" value="XM_066815737.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048797"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022025">
        <property type="entry name" value="Amidoligase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847:SF1">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12224">
        <property type="entry name" value="Amidoligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="42039" checksum="1F2362AA73206D17" modified="2025-10-08" version="1">MSDNDSIHFSDGSTEFDNSTITAANDSLETPDESLITPDDPMTMPHNSDIYFGVEIETVVKMASELVVRANSSDHFEKFCDPQCLIFVNKLKPKLKSQLLLHSDDYRQWQFTRDPSIENEGGFTPSDLAVPLEIKSRQSELADVWSVIGSEMMTSKPEFFRGCSTHIHFSFSEQDQAGQYLDFPVHKARRIFLAAQIFEKAINDIMPDGWQNRSYAKSLQTPSSSKEEEDKHKLVDNLCEWWAGMKSCETMPELSRQVNFVKDFAENPLWKWGDSRYFKWNCFSYRPQIHYRTIEFRQPPLSLSPRDVKLWVDFVVGFVKAAVLVDEARIDAAAKTGDDDSIRALYYTAAETKDDAASSPRCRTETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJH0</accession>
    <name>A0ABR1VJH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665187.1">
        <property type="nucleotide sequence ID" value="XM_066815897.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048957"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="92"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="648" mass="73560" checksum="198E2E7D3A9BAFD2" modified="2025-10-08" version="1">MYYPRFREATDPQSPLNQSPDYQDIRLLFIEPARSDESRVSCRVEYHNTSEADWSPQWREVVASLGRPVRASDRLKWRKARPDVGRYTWVPIFLDGHDFQVTRNLERALRNLRDSNTLSERFLLWVDALCINQDDAEERAVQVARMQTIYTSAIETVVFLGSGDPAVEAALRFINAAGSAWNDPPKLHVAIDKYLAEATVNIGDQIIALVELPYWWRQWILQELVAGSDEKPFFYGKVQTTSKRIWQVFNQFERRNRHRLPRCAAFWDAVDKHPRHYRHPGEVKTFGEFGGPIGRRKFAFASDGETSMNTYQTLTTARKDSATNHRDYVYGLLGLVDKSISSHAKVDYGATVGDVYKDFTKIIIDTEKSLEILGHEEEPPYNANLGRKAICYFESLPQDSPEAPPIDLLHTKALIVDLLDGLSTANLETDFRDENKLYKGGYAEESFPTSSANANNAYMSDAALEEALWRVAGGNRDVRGIIPAPSHFKLLLSTELLEEHYDFVEKGSPNSWVNWVRRNADMKIAGKALLEHFRPAGLANMEVGEGESSIKNASSAIYRFEQACWSRRIAVTDKGYLALVPWYAQKGDSVVVLPGCSFPVLLRPLEQKLLVGNTFRLISPCYLHGVMDGELWRDVDMGARKLEDVVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKT5</accession>
    <name>A0ABR1VKT5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase S8/S53 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_010676</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664281.1">
        <property type="nucleotide sequence ID" value="XM_066814991.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048051"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045515746" evidence="7">
        <location>
            <begin position="21"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="152"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="9">
        <location>
            <begin position="554"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8070473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="685" mass="72821" checksum="11BDDAAFC7387992" modified="2025-10-08" version="1">MRVPSSFIVALLAAAAGGNALATAPAGPQPQSNQSKRYIIELKSQSDIARIQAMVERTPGLRVFKTFDHAVFPAISVECYGGHGGGDLETMTQIFHFEGEDGPGVDGIYESVPLQIIRPIEGESFSNDAAALNYSFHGMTGVEKLHKEGITGEGAIVAVIDTGIDYRHPALGGGIGDGYKVIGGLNLPRRGHRDESDPYIPDSFVEDTEGHGTHVAGIVAGKGEQFVGVAPDAKLLAYRVSDAKNVIEAESVRGAIEKAVDDGADIITISLGSDRGSPLSWGPLASKLVSKGVFVSISAGNDGKYGPFTLSGRALCADTLTVAASDPVRYPAYGFTASHHLGGRPDKTELAYTIWSFDSKAPVDPVPWPSTIVDWPIIPITRDISVANDACSPLAQSTAHMTGTIVLVRSGGCSLQVKLGNLEPFSPQYVLFYQDDSPFQTPPIRPKAAVIDKAAGEAIIKTILEGNLELKPDVSAPGVGKNGGRAAHENDPEWARRLMKRITSTAHSVPWAESDPTTVSKFFASPAQVGTGFVDAARAMAATTELSFHGRGFELKDPARFVSKHSVNITNVGMEPVTYTFSLQSAGGFDSSKHLPGHWSLGPVVPMHLDPLVSLPKSVIVGAGETKAVEFAFKPPTNMNSSSYPFYSGKVLIKANNSEEFGIPYLGAGHNIMIQIMEDRLEEYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VN33</accession>
    <name>A0ABR1VN33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cell division cycle-related protein res1/s.t1.c1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011471</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665076.1">
        <property type="nucleotide sequence ID" value="XM_066815786.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048846"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF15">
        <property type="entry name" value="TRANSCRIPTION FACTOR MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="10" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0183">Conidiation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0749">Sporulation</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="9">
        <location>
            <begin position="17"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="243"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="333"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="116"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="465"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8071268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="628" mass="69956" checksum="F61684194BF58F04" modified="2025-10-08" version="1">MVKAAAAATAPAAGPGVYSATYSGIPVYEFQFGVDLKEHVMRRRQDDWINATHILKAAGFDKPSRTRILEREVQKDVHEKIQGGYGKYQGTWIPLDSGEQLAQRNKVYERLRPIFEFTPGNQSPPPAPRHASKPKAPKVKAAPARAAWVPPPRQPDFETASQQLEDDTPDNVTIASASYMAEDDRNDLSNYPSTGHRKRKHEETVQDLTEQQHSVYGDELLDYFLLSRQDAPTLRPEPPPNFQPDCALHWASAMGDVDVIKQLKRFGATLNSQNIRAVHFTNCYEKQTFPVVIKELFDTVDARDNQGCTVIHHAAIMKSGRSVQLIIDAQDLNGNTALHLAAQTSAKKCIRALIGRGASTHIMNAEGVRAEELIQTLNASKPPKERAPQRSSSPFAPESQRHVSFRDALSESVTKLAVTYQSEAATTVQNKITPLVLEKFQDLAHSYDEEWKEKHEAENEARRILGNTQNELAAIRQQIAELEARLEPEEAAAKAVGDATMAQHEVLALLANQNKYHIQATVEKQLSMMNGNDAGDDTPETRQALAHELRDLILEQRRAEQEYVDALGLSGTSEKIDKYRELLKQCLDSGDAENLDSNLDDLIEMMEEERSEVAIAAPVPPTEPMMIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTC8</accession>
    <name>A0ABR1VTC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009181</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665458.1">
        <property type="nucleotide sequence ID" value="XM_066813496.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046556"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12365">
        <property type="entry name" value="RRM_RNPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034201">
        <property type="entry name" value="RNPS1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15481:SF0">
        <property type="entry name" value="LD23870P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15481">
        <property type="entry name" value="RIBONUCLEIC ACID BINDING PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="85"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8074518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="333" mass="36941" checksum="4833BB43E0C3BE36" modified="2025-10-08" version="1" fragment="single">MDSRSPSRERYGRSPTPPSRYSRSPSPMRRRRSPTRSASPAPRRNGRYRDERSKTRSRSRSRSISRSRSRSFSRGRSESPLRGSTKIVVEKLTKNINEDHLREVFGQYGPIRDLDLPMNRQFNTNRGTAYILYIHEADAEAAIAHMHEAQVDGATINVSIVLPRRKFSPRRPRLAVERTSIPECPRPDEEVAAVAEEVEGSEEDLEVALEDGDDAVRLAADLVVAADVEEEIATETTSTPTVPENAPAPFRPRRAEVARLRTVRGRPRPRLKDAVVVVEVAAEVGAIVSTTTGSAVLVTTATAAVLEAEAVATARIAEADFVDDWHEDSMRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTG8</accession>
    <name>A0ABR1VTG8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665397.1">
        <property type="nucleotide sequence ID" value="XM_066813435.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046495"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="304" mass="33705" checksum="92ADBAA2A2FE949E" modified="2025-10-08" version="1">MFFSRTMGTGGMVGGGVATYLVWIFLVPFLVGQVCECGVFQRHLESCQITNGTLTVRTYVESLANISKIAVHTEDYRHVASVLRRARIDSTVLSGALQFGGARWDYIKSTENQVKQYDAELLKSAHAWNSLNQILKSGTGQLIWMSERLHLELGNVVSLSAYIGHLLGSHNFLVTNRLSSGLMSCIESTLEILDRVQKKVHATETCTHSLNSLAHQVTRAAEHAAGIMYQDGVHRTADGLVYAQVSCGWFNLCGLMKPKPISSHDVTTLVHILEKQQKYHKEAQIAIEAIRSIITDTRHSLRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTT1</accession>
    <name>A0ABR1VTT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665605.1">
        <property type="nucleotide sequence ID" value="XM_066813643.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046703"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="123" mass="13756" checksum="65491BEC0DC0FD91" modified="2025-10-08" version="1">MARPLCQHRELVNGPSSAIYPKQKQNGKCCEPDMTTLLPGDVRLGVPSCRDPRSTWHIGIFRIAKDKDFTIRFPLMHPLAQFSSASREPACMDQSNLQSPRAPAIYLDADATGYLGIQLYIHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUJ6</accession>
    <name>A0ABR1VUJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Nascent polypeptide-associated complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009588</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Part of the nascent polypeptide-associated complex (NAC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the NAC-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665865.1">
        <property type="nucleotide sequence ID" value="XM_066813903.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046963"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22055">
        <property type="entry name" value="NAC_BTF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039370">
        <property type="entry name" value="BTF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10351">
        <property type="entry name" value="TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NAC-A/B" evidence="8">
        <location>
            <begin position="38"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="9"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8074925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="154" mass="16685" checksum="35FDE1B23870D876" modified="2025-10-08" version="1">MADVQEILKKKFGGAAPSRTGGKGTPRHKQKRNVARSANDDKKLQATLKKLNVQPIQAIEEVNMFKADGNVIHFSAPKVHAAVPANTFAIYGNGEDKELTELVPGILNQLGPDSLASLRKLAESYQSMSKGEKEADDDDIPDLVAGENFESKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUV3</accession>
    <name>A0ABR1VUV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009687</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665964.1">
        <property type="nucleotide sequence ID" value="XM_066814002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047062"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046381102" description="Serine protease" evidence="7">
        <location>
            <begin position="16"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="43"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="185"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="56718" checksum="13BBA5884C3A5EBA" modified="2025-10-08" version="1">MRGVIALSLACVAAAAPSFSYETIHDGAAPILSSSSADEIPNQYIIKFKKHVTESSASNHHSWIQKIHGAREDERIELRKRGQFPIVEDVFSGLKHTYKISADFMGYSGHFDDETIEQVRNHPDVEHIERDQIVHTMSSSKDEPELEKNAPWGLARISHRESLGFGNFNKYLYAADGGEGVDAYIIDTGTNIEHVDFEGRAKWGKTIPNGDEDIDGNGHGTHCSGTIAGKQYGVAKKANVYAVKVLRSNGSGTMSDVLKGVEWAASAHLDTVKAAKAGKRKNFKGSVANMSLGGGKSPSLDQAVNAAVDAGIHFSVAAGNDNQDACNYSPAASTKAITVGASDLGDNRAYFSNWGKCVDVFGPGVNIKSTWTGSKTAINTISGTSMASPHLCGLTAYFLSLQPSKDSEYGMAEITPEKLKNNLLSIATKGALSDISSGTPNLLAFNGGGSSNYSSIVEKGSYTAKKQQSEKPITLEDLEQAIEKDLNVVSGSIVKGVSSFSNKAEKVSEKIHHMVEEELEHFFEEFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVB5</accession>
    <name>A0ABR1VVB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit g</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_009430</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase g subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665707.1">
        <property type="nucleotide sequence ID" value="XM_066813745.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046805"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006808">
        <property type="entry name" value="ATP_synth_F0_gsu_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12386">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04718">
        <property type="entry name" value="ATP-synt_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8074767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="22838" checksum="ECB5DDFE9D01805D" modified="2025-10-08" version="1">MSSMALARPAIRQSGNLSRMAARRFESNTTAKANEAAKAAKESAANASAKASASASEYAAKAQQGLSRVSSAAGPAITGAAKGLANSLGKVGGRTGKVVGFAERQIPQVLYWGRVGSELAKIVFRNQKMSPPSMQTFQSYYQNILNTVRNPSALAQTASKASQQPATMLQQLRNVNNAQLIAGAVVAAECLGFFTVGEMIGRFKIIGYHGEHVAEHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVT2</accession>
    <name>A0ABR1VVT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Eukaryotic aspartyl protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666284.1">
        <property type="nucleotide sequence ID" value="XM_066814322.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047382"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="220" mass="22811" checksum="7EFAC241E83B510C" modified="2025-10-08" version="1">MESRVKAQPGLEVAYHDAPELSNHGSDGLEVSHNSSGALKGGDDAPCPVDTQQRRRRICGLRRVQFAIIVSVLGAICVVGAVVGGVVGSRSSNGTSTSTSAFPTATSGILALDCPKIDGTQKPYTVSGSPNAYTFQFTCEYDATGSRGNGAKFNTTTVDGCVEKCAEHNHEESDTACGGVVWNGNLTSSLTLGGNCYLKMGMAHTTDRCNGCVVVAAMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVY3</accession>
    <name>A0ABR1VVY3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010068</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666345.1">
        <property type="nucleotide sequence ID" value="XM_066814383.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047443"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF52">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="84"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="546" mass="58554" checksum="9B8A0AC3DF67BE47" modified="2025-10-08" version="1">MDNSVSATATTSNPQSSEATRPDDSVNDRVDAPSPLREPKSDGQETPSVVPKETSPNDALVVTWDDPDDPQDPFNWPLRKKWCAVALGLLASFVCSTNGSILAPAHAALSDEFGGIPDGPSSSFQHAYWTTTSWGVGAALFPLLLFPALEDWGVRPVLLGTYFVFVCLLVPVGFARSFAVLVAARFFSGGCVPLMSDAVASIASNVFQCERARSIPIALYVLVYLGATSLGPVIGAAVLQHLSWRWIGHIELIVTGALFPVLFIGLPESRGAAILRAKAKRLRGEGKVAFTAEEVDPTPLRQLMIKSLTRPLYMFFTEGVVFVTALWAAFSLGTIYLFTHSVEQVYGELYGWTSVQAGYVQSAIVVGEVLGTILSLSTNHWYEASATRNTEVPGTPIPEARLYTAIIGGLVGVTGGMLVYAWAAYATVHWIVITVGLTMVGLGTTAVVISIANYLIDAYSKYVASALAAVGLAENLSIAFLPLASSALYTDLGFQWASTLLGLVSLVLVATPFVVIKWGREIRSRSPFMKEAVIVRRMNSGSTFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW36</accession>
    <name>A0ABR1VW36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666399.1">
        <property type="nucleotide sequence ID" value="XM_066814437.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047497"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF3">
        <property type="entry name" value="C6 FINGER DOMAIN TRANSCRIPTION FACTOR DBAA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="607" mass="67986" checksum="40BBEA3474366279" modified="2025-10-08" version="1">MKSHTETRQLPGPACEECRRRRSRCDRVRPKCGLCTEIGRNCVIMNKRSQRGPKKGQLEELRSRVGNPRQVIQPTLELKLVSQQGLDSVLPSTESIESVFKGDPVADSGPYESSETTENEEVMAALEFDWGSSYQEIESQTLIGSPAYWHGTFDFVSPPSFPERQKLPDHTPPTFTLGSTIQNSILCDGGVEISDLTRVELDLLYFERVHPIAPIIHKKCYFAWAADPQPTPARACLRFAMWTVTTAMSAQFCALGDALYATTRRLLETQEVHNEAGLPWMTKTSTCTSVKIKHELVQAWLLLVHYEFLRKPESQATLTFQRAFRLLQLSNMFDIDLLDDRAQAKSTYAAPPPSERLPGSEDDWITTEGKRRTLWVAFILDRLSSMLNGRQFLLHEEMVSMQSIRIRTRLPMPEAEYQTGREPVVMCFLSDTMLNETGDNTLSNMAECVVLANIFGRCLTHERLAHTMPLLGSGSDSRAFWARHNWLAAAVERARQRSATGCSNSPVVVANTQTSPNDHGGRSKCDPMRALNQSLAPTAAVALSRTAGAINWERPDYQSMTASYKALATQAACEVVTLMKHAPRIAFLKVCWSQRSGRHPLAHGVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWU6</accession>
    <name>A0ABR1VWU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">mRNA-capping enzyme subunit beta</fullName>
            <ecNumber evidence="8">3.6.1.74</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">mRNA 5'-phosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">mRNA 5'-triphosphate monophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_010399</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67004"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
            <dbReference type="EC" id="3.6.1.74"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:67005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the fungal TPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.74" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666676.1">
        <property type="nucleotide sequence ID" value="XM_066814714.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047774"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07470">
        <property type="entry name" value="CYTH-like_mRNA_RTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.10">
        <property type="entry name" value="mRNA triphosphatase Cet1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040343">
        <property type="entry name" value="Cet1/Ctl1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004206">
        <property type="entry name" value="mRNA_triPase_Cet1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037009">
        <property type="entry name" value="mRNA_triPase_Cet1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28118:SF1">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-TRIPHOSPHATASE CTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28118">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-TRIPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02940">
        <property type="entry name" value="mRNA_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="4 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="mRNA triphosphatase Cet1-like" evidence="10">
        <location>
            <begin position="668"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="154"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="233"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="588"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="233"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="379"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="454"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="468"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="494"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="529"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="599"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8075736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="953" mass="104625" checksum="5A2A0F36E0A9C93C" modified="2025-10-08" version="1">MDLNSMLNKDSGAGGASRQPPPPPASLAKTPSSSMSATPHTPVQPAHPSHGFRDYGHPMHASPGPAPAASPREYAAVAAHPGFPPSAPYASPTSYNAPPPMDTLGGQPPSDPSARGYERPTVTRQRVRIEPIPIQAYTDLVHQRCERWRLQYGGYPRDPRDSYASQGGAAPVGMPTPHGSVSYPVPGQQVMPQTPPVGTPGGGNHMYMQQQQQQQQLQLQQLQQQQQQQQLQLQQHQQHQRSQSLQSASASTPTSAHGPHQPPFGTPSAYGPPGGSMGSPVATSHGPPHFDQQGHFQQQQSHPHQRQTSQPPTPLAAPLSGTPRQSVSTINQSNTNFAQPPSPYQQRTPSGAPLAAYPLHPQQQQQSPYHASPPPPQPSTIQRAVSNSSHTAPYDTISESHRRSQSQTSRSERERSISVSPKTRVPSLPSSAGEPRPSSKGGAFPGAPPEFSHPQPQLTPQQQQQKPNHNISQVSASTAVMEGVQYMQQPREATPGKRKLDDRDLRQDELEGATNRRPPPPGINGNHGTAASRTSASTSTSPLLPRRKKLRCTANNAPAWAQNYRTQPPNASRNYTLRAKAHVTSQAPAAGGLVNGNGHRSESNVKSEHVSRPTSPEATRSVGGGTSVKMEDHNAPPPPLAAEEGYTFEGQPFPLECISLVNKPIDFLVKAVGDFLFINVIKNPHLESIQRHGVQFEIEAKFGTIIDRDTDDRLEYPLHGECVLSPQARIGFRSSMSELQHRSMNEWLNGQVVATNPHNNGGRRNPHVQIHYKHRREIDKFYELHSSMIGRLPHAVQAMMSPKHALKARITTDQKTGEVLAKIVKARVGDLNLYLPQCPVDCRISINLEWEWDGPPEEIMSNQMPHREKQPDREKDRLSYKHGFFQVDLTQVKRQLAGRGPEKEHELEVELDAGILLDHGRFLESQGESKYQDIVEMLVNNVRALARRCPYPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXI2</accession>
    <name>A0ABR1VXI2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665524.1">
        <property type="nucleotide sequence ID" value="XM_066813562.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046622"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="150" mass="16854" checksum="5E1B930AC308BEAD" modified="2025-10-08" version="1">MYHQYMESRNLGHVAGTYAFIAETLDLIPMDGRSDFLYRVDPILLGTHTSIQALSTKPTRTALGDLLLHLQNDKINFTTLMKEVDKLAFYQGQAKKPRKSGKQKGKSKGKSKGKAKNKNKATKVRLTLPEGVMRYVESIERLCKELAPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZU1</accession>
    <name>A0ABR1VZU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010343</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666620.1">
        <property type="nucleotide sequence ID" value="XM_066814658.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047718"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF168">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="524" mass="59436" checksum="B4597E6B66177FCA" modified="2025-10-08" version="1">MVILTAASQPAQHGLLKSVVLPCLLALLVVIIVQQFRSWYRLRHIPGPFWASVSSFWMVQKALTGKLHEHLRDISEEYGPLVRIGPNEVLSTDPDVLRMMSAVRSSYTKGDFYETGRICHGEDNVVSQRNEAEHKALRAKMASAFGGRENEGFGFGAGIDRQVTLFMNLINDRYCSTATEYRPLQFFEKVSFFTLDVIGDISFGEPFGYLSQDQDLYRYHEIHDSSLPAMNIMSTMPWLAKYAQAWPFSKFMPNEHDQIGFGRLMGFAKSFVDRRLQPGAKPQKDMMQAFINSGMTRAELIQQVFVQTIAGSMTTATAISMTMLCLITTPAAYMALRREIDDAADLGKLSSPISDSEAKRLPYLQAVIREGLRMYPPTTGLGSKQVPKGGDIVNGCPVPEGTQIGTNYFGLMRSKELWGYDANVFRPERWLEASEEKYRFMASLVELEFGFGKYQCLGKPIAMMELNKVFVELLRRFDFTIVNPQTPIRAWSAVFWVASDFWLRISRRADRQVYYEKECTFCCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W956</accession>
    <name>A0ABR1W956_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007838</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667495.1">
        <property type="nucleotide sequence ID" value="XM_066812153.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045213"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF24">
        <property type="entry name" value="3-PHYTASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="538" mass="59710" checksum="8BD6C5EBB0AAB7F4" modified="2025-10-08" version="1">MGIKDGIATMFNRQWEWLPTSHKYSPLPPAAHSRSVQPPAFTTWTDQGRRHAIMKLAMVGVLIVVALFSVASYASVFNPVDTLCRYRRNTNSSHRQSPATGSCDTALHGFTCLPEISHSWGQYSPFYSVNSDISRSTPKGCEVTFAQILSRHGARDPTASKTAIYSALVQRIHDRVTEYGKGYGFISNYNYTLGADELSPFGQQELVNSGIKFYKRYQHLTRQAVPFVRTSGQSRVIESAQNWTQGFHQSRLEDKLSNETDAFPYDMLIIPEDEGFNNTLSHANCKAFEDGPISSVKDQAQEAWLQIFAPPIAEKLNQNLPGANLSLTDTIFMMDLCPFNTVADINGRISPFCGLFTRDEWNGYDYYQTLGKWYGYGNGNPLGATQGVGFVNELIARLTGKAVVDQTTTNTTLDGSPDTFPLNQSLYADFSHDNDMTGVFAALGLYNSTEPLSNTTKASPRETKGFSSSWTVPFAARMYVEKMTCGDSAEEFVRVLVNDRVIPLQNCDADALGRCRLSRFVDSLSFARAGGKWGQCFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAD2</accession>
    <name>A0ABR1WAD2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667921.1">
        <property type="nucleotide sequence ID" value="XM_066812579.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045639"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="281" mass="31565" checksum="29047518F95125E3" modified="2025-10-08" version="1">MPAGVFAPRPTPASDKETNKKPPKDSANDSAKKSIRKFSLERFEKPSSSKGKNADKEPTKSGEQLPGELYVQAHSKASGHHKQPIAEDANSDESTQGKGPDPQPKNTRNHHVCEYFHEHSPEASQDAGSGKHICVLDPEPLADEPESTREKQKKDHGHAGHDEVVGVIHQADCEEHPEATEEHLVADNPRLGKMIAVYQKIEAKVGRSEEEKEKRARAKSEAKEEKEQKERAKREAKEKKARERQERKEKRAQEKQERRAEREKQRRAAQGARGHGVIHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAG0</accession>
    <name>A0ABR1WAG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667980.1">
        <property type="nucleotide sequence ID" value="XM_066812638.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045698"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="11904" checksum="1DBB64E1AC8F190D" modified="2025-10-08" version="1">MRADWTNAPRISTWIVAVPASTAAVYGLYHWSAVACDLEALRVDNDSIVLIRPPSCHWQGCCYKTPSDMGRNRYPISGTKQGPPRSMSVDISLDLLGETWGPTPSVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAM4</accession>
    <name>A0ABR1WAM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CobW/HypB/UreG- nucleotide-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008377</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668034.1">
        <property type="nucleotide sequence ID" value="XM_066812692.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045752"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF31">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="2">
        <location>
            <begin position="33"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="3">
        <location>
            <begin position="720"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="529"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="627"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="823" mass="89112" checksum="49B9BB74FC5DC9AD" modified="2025-10-08" version="1">MDADDDFPPELVETTSGGVVEPEEPSEKPLKVPITIVTGYLGAGKTTLLNYILTAQHGKKIAVIMNEFGDSIDIEKSLTVNKGGEQVEEWLEVGNGCICCSVKDSGVNAIESLMEKKGAFDYILLETTGLADPGNLAPLFWVDDGLGSTIYLDGIVTLVDAKNILKSLDDPAGKVEGHDDHETHGPLMTTAHVQISHADVIVINKSDLVDDAGLDKVKDRIQAINGLAKIHVTKQGVVPELEGFLLDLHAYDKVDALDTAVKGHSHLDPTISTVAINVPSLLPGQLAKIDGWLRSVLWEGDVPGIDDKQSEGLEVHRLKARLVFQDGQVKMVQGVREVFEIFDAPSQSAPEHGVETPLQGKAQYRKPYEGCRQDSVVANNNRNSLEEGCRIGYQMARWVWDHVRNCDAAFWASNSSRQLGGNISFAQSLSGSSPATPLDLSEFPSLSNNAQLPSTSQSSLWSSAGNRNMPPIQRNQGTPLSQQGQEDIFSSTSRIGSNQGSFRFGGSQGSVGQPSQPQPSSIDDFPPLNNNNNSGFRNGNGDIGQERGSNLMSTLGFGATTSPAPGMQGSRAGNGLLNALSENSRSGQVRSPDVSSAPGSGRPQDSRGAIGEEQRQKPPGFRDDSLASQSSSQEAAAQSSESRNPLGAIGNDVPLGAKAKDEKDTQSPSVNDPLAGMAPIDKWGIKGLRTLMNNYPDYQAAITGIDPQQFGLNLQSTDVSNVQPLDNKISSFNEETLMWIFYSCPGDLKQHQAAMELNNRNWRWHKKHQLWLTKDEIMTPRLLSHQHEQGYYIIWDTATWQKTRRELVLYYADLDTANGAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAQ0</accession>
    <name>A0ABR1WAQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit ASK1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_007414</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex ASK1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667071.1">
        <property type="nucleotide sequence ID" value="XM_066811729.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044789"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013964">
        <property type="entry name" value="DASH_Ask1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28200">
        <property type="entry name" value="DASH COMPLEX SUBUNIT ASK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28200:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT ASK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08655">
        <property type="entry name" value="DASH_Ask1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="87"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="272"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="329"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="383"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8079596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="453" mass="49721" checksum="3A9EA86F7B0067F7" modified="2025-10-08" version="1">MSLPGPSRNLTLTEELEKLEQSITLTLQEIDHNFSKAHRIVTSSILPLVEQYGEHSKNVWEASKFWKQFFEASANVSLSGYEELANEGDTTAADETTRLGDTTTTTDDGGYADPTSQSVVADDQSTYHEQRQHHQSHHREIEDSLLDDGTLEGSTPRPPATKSLRGQEMQFANFGSPYENLRREMKGEEGEGLDDHTAGSDLFADDPDETTQQLQQDRLPDMSMTPHSSSLLEAPTPMQGGMRTNLFGTANKDKNKDPLLHRLLDKNYRIQATPHKGGGRGLSPNRGAGAGAAVPETDRTRRALWQDSPQSSPEMAAPTLRTNLYSAMSPLKGQRGRPAAGRPSTEGPRTPGVSVQTPAKKRDVFAERQSSGKGKGKGKYEPDEITWDSDDDEDGMFGGMSPPKTIQFALPPSKLMQTPAREASKRIVEDILLTAGAAPEYGSTPSTVRLWFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBB9</accession>
    <name>A0ABR1WBB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668281.1">
        <property type="nucleotide sequence ID" value="XM_066812939.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045999"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046420286" evidence="2">
        <location>
            <begin position="22"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="324" mass="34281" checksum="E990CB1E793661AD" modified="2025-10-08" version="1">MTKMLWGTALATSILAAGAHASVDAMGGMAPVEPRMANAGVPMPVLEERQDSNLNLNPSNSTNNNPNAGMNMQQWNTDTLKACQDALSQLTTATNPSGTAVCYNLPSLDTKTGAFMADLRLFQVSQPNGAFTGIPAERIQVGLQYRGASVSPLQSNQARSLDNDTPDLVGRANSMTPLQSYMFVGQIDQAQMAQPMTMGVLEALVLPQVTLSATNAGGASVSTNVSSNEAAFVNGIFSKEVIMSDIARAQLAVNDLVAGLQNGTVAFVLPGVELLIFPIGLIITSVWMVVGFAAYGLGTFERINHRHTFRTRKLRAGKGAQSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBG9</accession>
    <name>A0ABR1WBG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ecp2 effector protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668312.1">
        <property type="nucleotide sequence ID" value="XM_066812970.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046030"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="22112" checksum="99C48DB3A0057324" modified="2025-10-08" version="1">MGNCTLPPRPPVSSQVPVPPTSTTSASKPLSTLPPVMPKPSGFPVVPMPSPRPDFTAPKLPNCGEGTQLVCIGADGGTAQGLNRDELVRAAAHLRSVADTEGDPYWTMDSESQCSEWQIDLGGDAGAVMALAKHIDCGVKSSVLYRDLARTIDGGGDEATTVQKAASLLGACGEAGGMVEVVVDVESAAYNTLEYYDSGAKPWGIVLKLVKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBS0</accession>
    <name>A0ABR1WBS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008769</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668426.1">
        <property type="nucleotide sequence ID" value="XM_066813084.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046144"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF55">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046342960" description="3-phytase" evidence="4">
        <location>
            <begin position="18"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="550" mass="60312" checksum="211E32AAF262AC7A" modified="2025-10-08" version="1">MQSVLSLSLALTAQVGAMTIPAEPFAGSPTSDIYPPPGSNFRQHAALPPESVVGFAGPTPTGVEPAAVQTAPLYPYNEGDSSSFPLVAPNAHGAGVDSTFNMKRYWGNLSPWYSVPSAHYGLPDASPLIPEGCTITQLHLLYRHGARYPTSDAAPARFAEKIANATKSEGGFEVSHDLKFLADWTYKLGAELLTPFGRSQEFLLGLEHRQLYGELLNNFTAQGALPVFRTESQDRMVKTAINFAAGFFGVPEYQDEVNIEILVEASHVNNSGAPYDVCPNADEKSKGDIGSGVANKFAKHAFDATLARLNSQISGLEFDDKDIVAMLELCSYETVALGYSAFCGLFSEEDFLNFEYYYDLKFYYNNGPGSPVSAAQGKGYLQEYVARFTHEYPEPYSALNETYDNSSTYFPLNQSIYADATHEVVVLDTLTAFNLSALFKGPPLSLKQNERRNSFSSSRVVPFATHFTTQVLECPAYQPTKQIRFLVNDAVLPINESYPGCEANPHGLCSFDNVVSVLLKRIEEIDFNYDCYENYTAEAGVDYNGRAPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCU4</accession>
    <name>A0ABR1WCU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668302.1">
        <property type="nucleotide sequence ID" value="XM_066812960.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046020"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="155" mass="17467" checksum="0CBDF9E5610D5335" modified="2025-10-08" version="1">MLPMLGEKEGFGNESETRLHETDDLNLLASRRTLRQREPQHSRAISSGVRKLMMPPPPRCQSRDDAFIPWSESLRGGWEEATYLPAFRRNEDWLDAERDNLSTTLEAAGLVDQRVKKGGPDQGSSYMPGVRKDSTGWTRTVLAPVVWLVQMTAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEQ0</accession>
    <name>A0ABR1WEQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4'-phosphopantetheinyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668104.1">
        <property type="nucleotide sequence ID" value="XM_066812762.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045822"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="20132" checksum="8738D6C19133E212" modified="2025-10-08" version="1">MSILGLGNDVCHIPRIYRILTSCHAQRFITRVLTAEERSEPRPQALLRCIGPRPSSRFDQSDAPWATGASDNRIPNVWKAAVFMAGRFAAKEAAIKAHSSRRLTFEDIRIVRTRPAARPLKGVDDEKDREEEAGHGDGTNDAALSSGPPVAVIKGYPPGQPDTTAMLSISHDGDYAAAVCLSVQGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL38</accession>
    <name>A0ABR1WL38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668721.1">
        <property type="nucleotide sequence ID" value="XM_066809798.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042858"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="1">
        <location>
            <begin position="19"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="143" mass="16373" checksum="7C5D47633D935CC0" modified="2025-10-08" version="1">MQDIALYKTGLASVFQDALPRHLKMVSIFEEFNPQLEAELDRRARRSGHHVNQYLGEFEASGDDELEKALSRSYDLEHLSASFLITAERFIYAHFSHSSMPLPGKWHRLRSLARHMELRTQSLGRQGVGKEGCFGLLPAECRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLF3</accession>
    <name>A0ABR1WLF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668854.1">
        <property type="nucleotide sequence ID" value="XM_066809931.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042991"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="33324" checksum="68800C781E8106F3" modified="2025-10-08" version="1">MSLDLQDSHNFPIVRMVPTGSTFKPEPEPGLNADQFYAINGHIFKDFRIGDDMMLSRKETVVITVGGNHINVHRELLVGCHAFHVAFTHNMLENKNKEYIVQYELENETNSQFELQAHIILFLALYGATKLPEDQYNFRGSAGPILVRAVALAEYRMAEDYVNDRLNTMITKHFNRMVDWKTTIPCMDNSLQLELHRGYLMEINDTFIAYKCSNIRDRRFPERAFGNLIALHCPARAWEMFQSQVDEDLARRVATAAMYMFGRLHISGEVFERTTFSNADLSLFRFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLH2</accession>
    <name>A0ABR1WLH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668853.1">
        <property type="nucleotide sequence ID" value="XM_066809930.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042990"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="125" mass="13925" checksum="066523671D8A24DC" modified="2025-10-08" version="1">MSAKRKMSTALKGASYYDNATCVPLARLRRCAPPYSQWIVARGTAVCTQHPLPAPGTSTLVDANMFDPFPNPKRALVGGAAYSFVDAVTRYPRQYHHPFPSPMLLSFPCRRQHSLPVPGYMHYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLW8</accession>
    <name>A0ABR1WLW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Matrin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_005765</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669003.1">
        <property type="nucleotide sequence ID" value="XM_066810080.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043140"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052092">
        <property type="entry name" value="SF3A2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031781">
        <property type="entry name" value="SF3A2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205:SF0">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16835">
        <property type="entry name" value="SF3A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="11">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8084494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="246" mass="27908" checksum="595CA6EB75D92CF0" modified="2025-10-08" version="1">MDYQNRAGSKFGGGGVASSSATTADRRERLRKLALETIDLDKDPYFFKNHVGSFECRLCLTVHQNDGSYLAHTQGKKHQTNLARRAAKEQKEGKGQIDERTGLPVGVVGAGFGALGLGGAKRNVVKIGRPGYKITKVRDPVTRQQGLLFQLQYPEISEGEVPKVRFMSAFEQRVDDPPDKNFQYMLVAAEPYETCGFKLQAREIDRTGERYWTWWDKDLKEFWVQVMFLTEREERYVGVPGLPGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM63</accession>
    <name>A0ABR1WM63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005855</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669093.1">
        <property type="nucleotide sequence ID" value="XM_066810170.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043230"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="21857" checksum="3BB78231358883EB" modified="2025-10-08" version="1">MSATGPSRVLEAAASGIGQAGRMYKGSKTGVVVSAGLMDKTVKIRLWGQRWEKHVSKVLIYLPIGSLLLFRRPLDDIEREEPKIHDPANSVRKGDVISIAAGWRASSRKKHVVKHIIAPYGQPIDARPPVPTEEELKADYIAERVAKIERREAAAKEHREAKQREQAEAEARRAQKLAKARQHQQEGTTTTSTADVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WML9</accession>
    <name>A0ABR1WML9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005533</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668771.1">
        <property type="nucleotide sequence ID" value="XM_066809848.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042908"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF13">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="363" mass="40017" checksum="695EE41BC1A678D0" modified="2025-10-08" version="1">MYQVRNHLASPRLHFPATYSIRAAGRRLDPRRGGRELRRPVRRTLPVPGVAVVDGDVLIDLSRFAQIEYNAEHEKVVVGAGLRWRDVYDYLDPYGVTVVGGKGLDAGRYGLSCDNVINYNVVLADGSTVNANEYSHRDLFWALKGGGNHFGLVTSFTLKTYPLPPQIWGGTRVIAWDRLDDVLDAMLEYETSGSPDELASVNIDIGATNETIALTLVYLEPVDEGKKTPAALSVFDRFEESTTMDTTGIKTLTGLMSEFPSSPPIPRRSRKAALPGNALGLEPDAAADKTMRVAGDALYAEIEAVAKQHDGRLRYLSMNDANEGQPVIASYGDDNVRRMREVREHYDPHGVFDRLLAGAFKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMW6</accession>
    <name>A0ABR1WMW6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_006093</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669331.1">
        <property type="nucleotide sequence ID" value="XM_066810408.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043468"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF37">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="12"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8084822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="510" mass="56510" checksum="968FC4B950E8A3ED" modified="2025-10-08" version="1">MPLSPHTYQFLVGVFASVGSILYGYDLGVIAGVVGSQVYKDQFSPGMPDGDPVRNGAVVSLFTGGAVFGAFFAGPSGDWFGRRWTIFIGSIIFILGGGLQTGARSYDYLYAGRAMAGLGVGFLTMIIPVYQGEICHPSIRGRVTGLQQFMLGIGALVATWLTWGTNVNLNDERQWRIPLGIQIIPAIILAALIFIFPESPRWLIDHHQAELGLHTLARLHANGDTNDAWVQAEYAQIQETIVFEHEHEAKSYTELFTKKSAFRRLFLAVALQASVQMTGVSAIQYFSVNIFKQIGISQENALKYQAINSILALIAQMACLFTIDKFGRRWTLITGNLVNCIMFMIATILLAMFPPDAEGGNGSAGWGFIIVTWLYNISFSYACGPLSWIIPAEIFDTHTRSKGVSIATMVSFAFNTMIGQVTDIAIQNVGGWRYFIVFTVCNFTNALFFWLVLPETKQIPLEEMNYLFTHAPWIVVGADKSKYRAGLGQDLERRAAEVREKGVHEEEYHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN49</accession>
    <name>A0ABR1WN49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006242</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669480.1">
        <property type="nucleotide sequence ID" value="XM_066810557.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043617"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF20">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
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            <begin position="164"/>
            <end position="193"/>
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        </location>
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        <location>
            <begin position="222"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
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            <begin position="438"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="282"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="391"/>
            <end position="407"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="465" mass="49632" checksum="87C7FC7C50E0EB45" modified="2025-10-08" version="1">MLDKRNSAAVAAVNGQPTASEPPTLASHPHLLGAGIDRSNSPHGSESSHYSRGGPGDLHALNMAATARSYGSPTSMHAHLTMPDHGMQATLPPGMMIPGMPTMQPAGNGMTVGYPQPVKMEHAQQQQQAQPPVKAFPCSTCGKGFARRSDLARHERIHSGIRPHVCDYPGCGKQFIQRSALTVHQRVHTGEKPHMCERCGKPFSDSSSLARHRRIHSGKRPYKCPYADCQKTFTRRTTLTRHQNHHSGTVEEAAAATAAVLAQQANKAASRQSRSDGDPGSNHGSPLNTPSPAHRNMSISPNAELASANAMRQNEYSYMNNNGGLPAHLRTDMHSQSPTSAPATFGTAMRPTSHPTSYPPPPTLEPSVEPHQPGPGSAGGSPHMGSVGWASPSHMSSHMPSPTHSNSGSAAYVYPDPDQSFTPNGMGQMYYGSAAAIRRPNSTDPGTNTFDPKHRPGEMWPTVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WND0</accession>
    <name>A0ABR1WND0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669496.1">
        <property type="nucleotide sequence ID" value="XM_066810573.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043633"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053018">
        <property type="entry name" value="Elsinochrome_Biosynth-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="491"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="58338" checksum="96ED9DF42FB6F25F" modified="2025-10-08" version="1">MAESAKFSMADCSILLQNGAVIEANADISGVGVVTAFILSAYLTFTAVLVAYLFGLVDSELLSPVDRRVFHIRSYPSRSTNGSEQQQQHEEQRAPSKLRARAEACLRTAILALSDQQIVIGIAIMGAGFQGLRAGALSAYHYQIVLYLAWMSSSVHLTAITLLASYLKRHRGVLAWRLTGMLVLFVMLIVGLVTTISNDWGIFSWPGIDSDKTGWAIPARCFWGNLRGAGVSPDAPIGFIILSVSYLWKMGQLFPSSRGAYHRWFRGPVERFLVHALRFTAEKRSIRSGSSWFWLWTFRLLLALALPVMVMFEVVSSFAASLWLSLMGLIFGTIQVLIPRGQMQPMTQSQEGTWGFGQLVPLILLIQPLGMVLEHVWTREPHDEDALELLRYTRTLPGSRDTQNEPKTELSREGQHNQYCLQQVLLTRICTHPRASTWPQEHAIVKDFLFSSKLFSFLVWLVQAAVITICTVVFHFDSLTIGNSRSSNWEFILDAIATFIGFGVLATLVMSPYSRTGRVPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP42</accession>
    <name>A0ABR1WP42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
                <shortName evidence="10">P5C dehydrogenase</shortName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
                <ecNumber evidence="9">1.2.1.88</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_006572</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate 5-semialdehyde + NAD(+) + H2O = L-glutamate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.88" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669810.1">
        <property type="nucleotide sequence ID" value="XM_066810887.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043947"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07123">
        <property type="entry name" value="ALDH_F4-17_P5CDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005931">
        <property type="entry name" value="P5CDH/ALDH4A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050485">
        <property type="entry name" value="Proline_metab_enzyme"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01236">
        <property type="entry name" value="D1pyr5carbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862:SF1">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="11">
        <location>
            <begin position="108"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8085301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="600" mass="65178" checksum="758A1B0A594AF3E7" modified="2025-10-08" version="1">MAGFRGSPNLQAVRALQSTSRLQATSRCGLRRQIPSVLTPTRSLSTSSPRLVQLATFQTPKVFNEPNHHYAKGSSQREGLIASYESMKKSLPLEVPLVIGGKEIKSSQTATQQNPSDHSQTVASYSLASPTDVNNAIEAALAAKPAWEALPFADRAAVFLKAADLISGKYRYDIMAATMLGQGKNAWQAEIDAAAELADFFRFNVAYAEELYAQQPQHNSPGVWNRVEYRPLEGFVYAISPFNFTAIAGNLVGAPALLGNVVVWKPSDFAIASNWLLYQILLEAGLPPNVIQFVPGPPEEVTKTVLAHKDFASLHYTGSTAIFRKLFGQIGQGTSEGRYKGYPRIVGETGGKNFHLVHNTAEIRNAAVQTVRGAFEFQGQKCSATSRAYVPKSLWPEFKSQLVAEVEALKVGEPSKPENFNGPVIHANSFKKLSGVIDEAKNDSDLELVIGGKYDDSKGYFIHPTVYATTNPNHKLLSTELFGPVLCIHVYDDAGPKAFEEICKVVDTTGEYGLTGSVFAQDRQAIRTAEEALRNSAGNFYINCKSTGAVVGQQPFGGARASGTNDKAGSANFLTRFVSVRTMKEEFNSTTKVAYPSNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP85</accession>
    <name>A0ABR1WP85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquitin-conjugating enzyme E2 H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006590</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669828.1">
        <property type="nucleotide sequence ID" value="XM_066810905.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043965"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23797">
        <property type="entry name" value="UBCc_UBE2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="19"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="173"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="208" mass="23969" checksum="70B3C709D882C1A7" modified="2025-10-08" version="1">MSSPRRRIETDVMKMYEIPRLRRYPFSRLTISLPLRVGQTRVLRLTDIRFPVQEFYVRFKGPTETPFENGSWKIHVELPDQYPYKSPSIGFVNRIYHPNIDELSGSVCLDVINQTWSPMFDMINIFEVFLPQLLRYPNPSDPLNGEAAALLMREPKSYDAKVKEYVQKYASKDAANEAGNESEDDDDMSSVASFGDEDDEPAGQMDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPD4</accession>
    <name>A0ABR1WPD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipocalin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669890.1">
        <property type="nucleotide sequence ID" value="XM_066810967.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044027"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024311">
        <property type="entry name" value="Lipocalin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13924">
        <property type="entry name" value="Lipocalin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipocalin-like" evidence="2">
        <location>
            <begin position="27"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="183" mass="20485" checksum="BA40B7420FFB3AE4" modified="2025-10-08" version="1">MTGLLPIPDQTAAPLPTEEEMSSQLAGSWRIRSFELTNDPNSTERITIVNRPCGRQPLGSLVLNQDPPYLCCMLTSTEAAQPIPSAIYTTASDEEVLRVARPLLSCMGRYELLRQEGGHGWMLKTSVDVAVDPNWMGTDQIQTVELREEYDGTMIMVLRPIQPFLFRSGGLFVARLEWEKITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPV2</accession>
    <name>A0ABR1WPV2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670080.1">
        <property type="nucleotide sequence ID" value="XM_066811157.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044217"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="362" mass="40862" checksum="C95E7C63CC2AEF6A" modified="2025-10-08" version="1">MDELFASLSRTLLDSLHVTPASSMRQDQWYKRCMESWKESNSGDVLTLTPKDARAEWAPKIYSFAKDLECVIRKASQQERETASKELSGDAAQGPLPQRAYGIKKLLERHESTGLLALATGHGHILRTLAELPPPKTSQRQCWEAPQGWVAALDETLEVLLFIMTMLCFEDQLLVNHGYARWLPAIRKYPVHPAVWTYLGSQGFGGIESRNAQAVGLDQKKLKDHLNWHLQTLSIAVVVMGECGIEHNPYLEDRIVNAFLHLSAKWLRSQVPEEKDDAFKEDGQSLADSGDEVKRPSRKKKDPLKLMEPGQNTIENLEEDKEEEASNSEEAAKLAAIETEEAKYGKKRSLKYRRKGHDSVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ07</accession>
    <name>A0ABR1WQ07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LSM2-LSM8 complex subunit LSM8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">LSM8</name>
        <name evidence="9" type="ORF">PG997_006890</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670128.1">
        <property type="nucleotide sequence ID" value="XM_066811205.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044265"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01727">
        <property type="entry name" value="LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034103">
        <property type="entry name" value="Lsm8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF9">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="8">
        <location>
            <begin position="15"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="112" mass="12182" checksum="540068090BC1B34C" modified="2025-10-08" version="1" fragment="single">INKSTCRSHPILTHGDSDSLVEKVCVMTADSRILVGELSSYDTQTNLVLLKAVERVIRSQDDDEPSSEVPMGGLYIVRGDNVCTIGLVVEDLDNSIDWTKVKGEAIGGIKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ21</accession>
    <name>A0ABR1WQ21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670143.1">
        <property type="nucleotide sequence ID" value="XM_066811220.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044280"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="108" mass="11550" checksum="E6B509E22595660A" modified="2025-10-08" version="1">MSNNKPTLLFLHGSMHTGEVWERVVPLLERKGYTRCLTPQLCFCGTPEPVPSIAPCIAQVQSLIADEVDAGRDVVVINHSFAGIVGCSTVKGFTAAPLLPKAEEESSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ32</accession>
    <name>A0ABR1WQ32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="2">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006915</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670153.1">
        <property type="nucleotide sequence ID" value="XM_066811230.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044290"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056584">
        <property type="entry name" value="EF-hand_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF82">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23617">
        <property type="entry name" value="EF-hand_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="4">
        <location>
            <begin position="349"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="463"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="616" mass="68949" checksum="FEBFA6E192FD730F" modified="2025-10-08" version="1">MASGRGAPQFDAPLLARLQDVFDRQAEPDRTWNKAQVEAFFHHVQADGPAHELDGGLDFDNFVRYMRSPAAEALAPAPVRTTQDMSWPLNSYFISSSHNTYLEGNQLTSDATTDAYKKVLLRGCRCIEIDVWDGGERFTDALDDGDNVEAGLEGAARTPNEMAGEKVGFGLRTMMKVSGWVTDNLLNEKGKRDMAEIQANWAKMVGSEPRVLHGNTLTKEVSFRDVCQTVKEYGFQTSDLPVIVSLEVHCSPEQQEMMVAIMQEIWGEHLLPPVELEDMERTAPSPEDLRNKILIKVKYVPSKQGRGGYADKATATEDPKGLGDIEGLEPEMGAPGAKQAKPPKIIELLSKMGIFTRGVSFKDMEQAEAEMPHHIFSLSEAMVETTHQQAPERFFKHNKHFLMRSYPAGTRVDSSNPDPAGHWRKGIQVAALNWQNWDRGMMMNDAMFDGSRGYVLKPNGYREETEGATPTSAIPHWTLHRLAVHVLAVQHLPLPDNVRSSDELHPYLVMDLSVEPHPLNITKREPCSVRTQVQQGVNPDFAQEVLTFHEIEGVTPELSFVTFQVWNDQPGPDLVLAGACLRLDRMKSGYRFIRLKNSQEMATDSILLVKIEKNMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQC1</accession>
    <name>A0ABR1WQC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Metalloprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_005484</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668722.1">
        <property type="nucleotide sequence ID" value="XM_066809799.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042859"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09597">
        <property type="entry name" value="M4_TLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052759">
        <property type="entry name" value="Metalloprotease_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032475">
        <property type="entry name" value="Protealysin_N_PP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43579">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43579:SF1">
        <property type="entry name" value="NEUTRAL METALLOPROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16485">
        <property type="entry name" value="PLN_propep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Protealysin N-terminal propeptide" evidence="10">
        <location>
            <begin position="69"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M4" evidence="8">
        <location>
            <begin position="127"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M4 C-terminal" evidence="9">
        <location>
            <begin position="262"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8084213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="434" mass="48296" checksum="6AE4C1EA3293D1D4" modified="2025-10-08" version="1">MASNHICCVVPPYLLIGIADSEQNEERLRISARNALEFNGHYCTKRKERFAALTVPRGFRGEAAEPPRQSIVPDVMLRAISESEDVDEQTRECAKRDLEHLQSVHARVQQAQGLRTGEEDDSSSAQQALSMGDKAKQPVASAVYRAVYDAQGTTNEARLPGKQVRIEGQKAVSDKAVNEAYDNVGNVLDFYLKIFNWKSIDNNNMHVVSSVHFGQQYENAFWDPSIRQMVFGDGHDFLHNFTACVDVIGHELTHAVTEHTSPLDYQDQAGALNEHVSDVFGIMVKQRVQNETADKADWLIGEGCLLPDVKGVALRSMKSPGTAYNDPRFGKDPQPDNFSKYKQTSSDNGGVHLYSGIPNRAFYLAAVAFGGYSWEKAGRIWWETMNSHQVPARCTFQQFADLTVDKANKLFGSDAAKKVQTAWTTVGVVRKSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQM5</accession>
    <name>A0ABR1WQM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670350.1">
        <property type="nucleotide sequence ID" value="XM_066811427.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044487"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF11">
        <property type="entry name" value="ISOFLAVONE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G12510)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="7"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="319" mass="34647" checksum="0778575AE3E3CFDA" modified="2025-10-08" version="1" fragment="single">MATSLPSKILIIGATGAIGKHITGAIASASLKSVSRVSILTSAATAASPQKQPLLASWKQQGLSVLTGDITKPEDVRAAYRDIDTVVCCLGRTALLEQIELLRIADEEASSVRWFFPSEYGTDIEYDETSKDEKPHQNKLKVRAVIRDEIKKLKITYVVTGPYADMFLDFKRGHESAGGFDAKAHQAVMIGDGNDKIGLTTMPDVGKLVVAALAKPEASMNKALKVQSFVATPRDILAEFESQTGAKFDVKYTAMDALKEEEKTAWAKSDPAAATFTLRRIWAQGKTLYEKTDNEALGLSPQDMEPLSAVVQRAIRGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY51</accession>
    <name>A0ABR1WY51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670973.1">
        <property type="nucleotide sequence ID" value="XM_066807355.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040415"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="85" mass="9458" checksum="F639787F4EFEDF4D" modified="2025-10-08" version="1">MKSYHVVDYRGGSDTGKYKANADYDRRMIMNVLHYAEPWPFMLGAPVTESAARSSMVHLAATRLTPHGTLHRHPASTTVGHPSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYL6</accession>
    <name>A0ABR1WYL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ethanolamine kinase</fullName>
            <ecNumber evidence="3">2.7.1.82</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003214</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.82" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671147.1">
        <property type="nucleotide sequence ID" value="XM_066807529.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040589"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF66">
        <property type="entry name" value="ETHANOLAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="406" mass="45723" checksum="4A91E3779967E481" modified="2025-10-08" version="1">MPSSTVNGAGSNGATVQIPIINLSYDPGNPDASALQLVTALHPDWAEPGAKVEFKRFTDGITNTLLKSVNEREGASKEDIDNEAVLLRAYGHGTDVLIDRQRETQNHELLMQHGLAPELLARFSNGMMYRYLRGTVTTPKDLREPRVYLAVARRLAQWHATMPCVHNESTTSNGTSPSDMVAPNKPPPNVWTVMQKWLNALPNKTEAEQSRQRSLQEEFNWLIEELSQRPGLGEYGLVFAHCDLLSGNVIIEPKGAGSPDTEESVAFIDYEYATPSPAAFDLANHFAEWGGFDCDFTVLPTRTQRREFIAEYIKAYFAQLPNKPADVDLNSEIDKIRRVQGLPGFYWGIWALIQATISQIEFNYAEYAEIRLGEYWAWKAEHTGQRKKNGDDLPVREKRWAEEEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYQ8</accession>
    <name>A0ABR1WYQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003258</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671191.1">
        <property type="nucleotide sequence ID" value="XM_066807573.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040633"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="59"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17145" checksum="F350DA304AE883B8" modified="2025-10-08" version="1">MDLPSDASDPTSPARTVSELPPDAIAFAGRMYDAARTGQVDVFKQALPLGLPANMTNEKGDTLLMLAAYHGHAELVELLIQHGADPNRINDRGQSPLAGAVFKKEDRVIEVLLEGLADPDLGSPSAMQCVTMFNQESVWKDKFEKAPGNGKGKPEMSTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYR3</accession>
    <name>A0ABR1WYR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671181.1">
        <property type="nucleotide sequence ID" value="XM_066807563.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040623"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="82" mass="8745" checksum="B58DA16A32357D1A" modified="2025-10-08" version="1">MTDLIYRRSSSNGRGRRGHLGDDDSLRFNRRRGEAHGQLRLSRLSDLRVAVGHGQGGPRSRGGDGGRAYAVASAGAEEGLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYV9</accession>
    <name>A0ABR1WYV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003253</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671186.1">
        <property type="nucleotide sequence ID" value="XM_066807568.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040628"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00880">
        <property type="entry name" value="2_A_01_02"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF23">
        <property type="entry name" value="FLUCONAZOLE RESISTANCE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="535"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="129"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="50"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="572" mass="63840" checksum="78E36027A9EC61A9" modified="2025-10-08" version="1">MESLLRDTFFSHCLRFVTGGRVFKYPEEVDSSIWTKYVHAGKSANMAQYGQTTAPEGSSQESPAQDPRQPTPGSRSSSATELDHDAITNNNHKRPVDPEKGRDHYIVDWYGPSDPENPRNWSRPKKFFVTFEICLLTFSVYIGSAIYSAGIIGVTQEFGVSPVAATLGLTLFVAGYGLGPMLWSPLSEIPQTGRNPIYILTLALFVVLQVPTALATNFGMLLAFRFITGFIGSPSLATGGASIGDMYSPSKRTYGLAVWGIGAVCGPTLGPLVGGFAVEKEGWRWSIWEIMWLSGATLILLIFFLPETSSANILYRRARRLRKLTGNDKLICEPELVGQEMTGKDVVSMVLIRPFSLLFTEPIVFALDLYIALIYGLLYVWFESYPIVFTEIYGFSLGKQGLAFIGILVGVFVVLAPFAWYHNKYIEPKFNDNGELKPEWRLPPAFIGSFTIPICLFWFGWTSRPEIHWIVPIIGTAWFSVGTFLLFNCVMNYLSDAYPEYIASVLAGNDLLRSSFGAGFPLFARAMYDYLGVDWASSTLAFISVAFIPIPFFLFKYGEMLRHKSKRARHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYX7</accession>
    <name>A0ABR1WYX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671228.1">
        <property type="nucleotide sequence ID" value="XM_066807610.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040670"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="285" mass="32619" checksum="20996D54B9EEF787" modified="2025-10-08" version="1">MTKSNNQPPTTTTSRKDYESAFHIITEQVYKLPNEERLAFKIDGITEEEVEEQLAAWKDAAKRGAATPWIEPVLASTHRVEIHPNQASFSIEQYRRKDNPALASRAGVSLIHLICTMKDPEPRHFDHHNFSFIREGIQEFKRRWASSIDDTEGKRFRLRVIETQLKAVIRRYVDAPRETPDTRPDGDALDIAVRAFRRLHDLKHNLLALRPEDFAFGIVPRGRVPEGTGAGDPQDFHFHIVATPGWCQQSCGTDAVAKMKDARAFQDMIQRVNTKNQRRIKVNAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0V5</accession>
    <name>A0ABR1X0V5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003972</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671905.1">
        <property type="nucleotide sequence ID" value="XM_066808287.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041347"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF54">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="478" mass="52789" checksum="BC2213CC3601F18C" modified="2025-10-08" version="1">MGDSMHKTTTSVDRKPSERSNGSITSSGQAAVLEADAALHRRLLWKRDIVLVPIMGVLYTLLFLDRTNIANARALGIGSPTGLEASLQMPSNGYNIALVIFYIPFVLAEIPANLILNQNKIRPGLFLGGQMALLGILGMCQGLAKSYGGLLAVRFLMEAALRFAWFFNFALAGPLFSGLLAYAIQNLEGTGGYAGWRWVFIIEGLMTVVISVPVIIFCPNFPHQAQSWFLKPAEREHVLAQLEASRGVETKGSASDQVSIWKVLIDWRIHLFTLCFFCCDITAASVSAFSPTILTELGWTNTVAQLMTMPVWASGIISSFLVTWLASRLNCRTPFVLGAILFQLVGWVIMRVYVPKAGVRYLALFLMSIGTFPQMPILMGWLSANLRGRKYLAVGMAWMIGFGNCANFVSSNIFIKAEAPRYVTGFTTGLAFTIVGFILVSCVCMLLVMKNKKREQLRLQMTAAERDSHDEVYFKFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1H7</accession>
    <name>A0ABR1X1H7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATPase get3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004196</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the arsA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672129.1">
        <property type="nucleotide sequence ID" value="XM_066808511.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041571"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02035">
        <property type="entry name" value="ArsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03112">
        <property type="entry name" value="Asna1_Get3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="ArsA/GET3_ATPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027542">
        <property type="entry name" value="ATPase_ArsA/GET3_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803:SF3">
        <property type="entry name" value="ATPASE GET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ArsA/GET3 Anion-transporting ATPase-like" evidence="10">
        <location>
            <begin position="27"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="340" mass="37485" checksum="028F94C996AE2A5D" modified="2025-10-08" version="1">MASTAVVSADDGLEPTLQSILDQKSLRWIFVGGKGGVGKTTTSCSLAIQLAKVRRSVLLISTDPAHNLSDAFSQKFGKEARLIDGFDNLSAMEIDPNGSIQDLLAGQGEETNADPLAGGMGGMMQELAFAIPGIDEAMSFAEVLKQVKSLSYETIIFDTAPTGHTLRFLQFPSVLEKALAKISQLSSQYGPLLNGFLGSNGSLPNGQNLNEMMEKLEGLRATISEVNTQFKDENLTTFVCVCIAEFLSLYETERMIQELATYGIDTHCIVVNQLLFPKQSSECDQCNARRKMQKKYLDQIEELYDEFNVVRMPLLVEEVRGKEKLERFSDMLITPYVPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1U2</accession>
    <name>A0ABR1X1U2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672292.1">
        <property type="nucleotide sequence ID" value="XM_066808674.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041734"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="146" mass="16725" checksum="FC75DAF65B6ED34B" modified="2025-10-08" version="1">MASLTASQLKRDLIDYRIRCWLANATYTKDSPLAAFSFDHIGQQSSQDPKVMFISTNNPDWYLRVTLYDELQNDEALDSLTKQQLEDTRHSFSNTIQQDTELVVALDILLDEGIEELSICGLWDLELLAGLGRTEKVGCTDYLRWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2N0</accession>
    <name>A0ABR1X2N0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672577.1">
        <property type="nucleotide sequence ID" value="XM_066808959.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042019"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="25"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="602" mass="67927" checksum="0E2F9C037A42F32D" modified="2025-10-08" version="1">MKRLATSGADASSSRSSALMVWPPSSGLKKLPYELMANIAMGLTIEEVFDLSLCCRHFQYLITENSFCKVIVCEKAPCSLEAQQAVRDGRYARALRRLVKRRRAIAEARPYIVAMVGLADSYLYSSGKLCYVYEDETQRWLRFLDLHNPSGRETVVDIPRLTTEAVPQSKNCHEYTFHVIHSAEGITSCLFSFALPDPESWLLILNTETQELVGAILLESTVRLFVRNSKSYLYYGTHSEYGPDGFRKWVLRVFDLTERHLSRRKIHLANVVGYEIDSTIMKQRDSWRRQHDEGPIDDRWGFMKLEKDETTGQVRIVESRKEWLTGQFGNRRSYYTTNVVFRDECEGSAEEEVENNIENNLPDDPLTRLLESSSNPNYMRPTLRRHAVSTLGMMSFRQCRQARAPRRLGGNGEEEKMYNRVIMWPEEPENPCSDPALERISRIMNPKDHQGNIEAVNDERSIIYATGGAGNSLKVLVWMSFDPAAKLPSTWSGGLSLVALSEAHANSGGSANECAGMREAAYGQALFASGYHGKAIRSQDYIRTCGSSSRGNPPGAVDMCSLRAGAPSEASLPDTFYCTEEPRVWARIEGAMYPYLIGQYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2R9</accession>
    <name>A0ABR1X2R9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672601.1">
        <property type="nucleotide sequence ID" value="XM_066808983.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042043"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="404" mass="43309" checksum="9AF45672FF69F018" modified="2025-10-08" version="1">MARRNSEGYAEEAEFPSESIEAEMQHKRARFWGTVHARNTPQPSEEGQNFTSSEGAQINNVDGHELPNEASQDANGTPRGSVGIRRSNATLVPSPDNGLEAASSKDTTPDIVVDSFHSQAGTSKYGLDPPKTPSDAGFTFEGDDFAQTREEIDFSAASAASASAFSSPWSTSTVAGGDYTTLPPPEMRYTSINGELHDVFDDDNEHAIADDNQSSCMGLSAPSSPVLPAGAFPRPKNASSSSSSASRARGSFGSAGLLGLADSQNLLGGGSTGRELQILKRPSLLNVDVSQRPASSGRELETRYLREGASSRHHHHDHHDAEKPQADPEALMKRSLSSNVLQDYHVREVVRQDKKKKTLQDGAKDKDTDEEGDEQRPGAGRPRSSSLMFLLAGATLASQMMRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2T2</accession>
    <name>A0ABR1X2T2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HpcH/HpaI aldolase/citrate lyase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004618</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672551.1">
        <property type="nucleotide sequence ID" value="XM_066808933.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041993"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308:SF0">
        <property type="entry name" value="HPCH_HPAI ALDOLASE_CITRATE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308">
        <property type="entry name" value="LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="299" mass="31919" checksum="FE0AAF5EE46A4A89" modified="2025-10-08" version="1">MLAKSVGLTSDNVTYDLEDSVTPTKKADARAALRDHLAGLQSRPKSISELAVRINAISTPYALDDLAALVPSPHLDAIVIPKVNSASDLTFATDALRRFAADRHRTATAANPVKLIALIESAQAVMNLREICAASPYLSGLIFAAEDFALDLSITRTPSLSEFLYARSAIVTAARAANLPSTIDLVCTSYKGEDGIRRLEEECRGGKAMGFNGKQCIHPSQVDVVQRLFAPGEKEVEWAVRVVIADEKAASAGRGAWTLDGTMIDAPVAGKAKAVVQKAESCGMDVASLKEKWKGQEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2U3</accession>
    <name>A0ABR1X2U3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fe-S cluster-binding ribosome biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672593.1">
        <property type="nucleotide sequence ID" value="XM_066808975.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042035"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013283">
        <property type="entry name" value="RLI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009945">
        <property type="entry name" value="PRK13409.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19248">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="Fer4_RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01868">
        <property type="entry name" value="ABCEFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="45"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="66"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="338"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="597" mass="67419" checksum="A90357A6E1637491" modified="2025-10-08" version="1">MSDKLTRIAIVNSDKCKPKKCRQECKKACPVVRSGKLCIEVAPDSKLAFISESLCGTYALKPFHSRASMRRPMLTIIGCGICPKKCPFSAITIINLPTNLESQVTHRYSANSFKLHRLPMPRPGNVLEYGLEDSQRQAQAQPGPPRQPPDWNDVIKYFRGSELQNYFTKILEDDLKAVVKPQYVDQIPKAIRGPEKSVRALLEGRASLDNLNEVLDVLELRHLMDREVNQLSGGELQRFAIGTVCVQKADVYMFDEPSSYLDVKQRLAAARIIRSLSQSDNYIIVVEHDLSVLDYLSDYVCVLYGRPAIYGVVTLPHSVREGINIFLDGHIPTENLRFREESLTFRLSEGADDFMADKARAFSYPKMEKTLGGFHLSIETGDFTDSEIIVMMGENGTGKTTFCKLLAGALKPDGTQKVPEMKISMKPQTITPKFDGTVRQLFFKKIRPAFLSPQFQTDVVKPLKLEDFIDQEVKNLSGGELQRVAIVLALGIPADIYVIDEPSAYLDSEQRIIAARVIKRFIMHAKKTAFIVEHDFIMATYLADRVIVFDGQPGNLDVTFRRDPTNFRPRINKMNSQLDQEQKLNGNYFFLEETESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2Y4</accession>
    <name>A0ABR1X2Y4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">P-type Na(+) transporter</fullName>
            <ecNumber evidence="19">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">PG997_004739</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="19"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672672.1">
        <property type="nucleotide sequence ID" value="XM_066809054.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042114"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="17" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 23" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="309"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="787"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="814"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="852"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="892"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="944"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="976"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="24">
        <location>
            <begin position="8"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="391"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="415"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAK8089778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1061" mass="117147" checksum="E709D0B652C17813" modified="2025-10-08" version="1">MAAEYPRHPYLSPVQDVFSTLESDPDRGLSSAQVAQLQQKYPPNELDVGGAIPWYTIFLRQLFNAMIIVLFFAMALSYGVGDYVEGTVLVVVIVLNVSIGFWQEYGAEKKMDALRALSAPSANVLRDGKTIVIPNAEVVPGDVVLLKMGDTIPADIRLFEAMNFSADEQSLTGESVPVEKIIENLDNEELGIGDRINIGYGTTVVIKGRGRGLVIATGMQTEVGKIAASTSGKQRKEGRSMNYKKYGKRQPVVGALKRTYDFFGKFLGLTEGTPLQIKLSKLAYMLFGCALILALIVFAVNNFTGNREVIIYAISTGIAIIPESLVAVLTITMVVATTVMRKANVVVRDLSALEALGGVTNICSDKTGTLTQGAMIVKKVWMPKNTIYTVRDSKDPSDPTVGRVTVSVVDPSAPPKDEEKRDFDQERSAGALKFDVPDEKLHNKPKKEEEAEATMNSDLESFLLAAALCNLATVRHETEANADERKWKTTGEPTEIALQVFAHRFQKGKKTLENDGGWKQVAEFPFDSGIKRMSVIYNGPNLDHSMVFTKGAVERILDLCTTVGLGDQQEELTDDYKEKILKQMDEFASLGQRVLAVASRPWEGLYEEKTSANDTEKDDALRSRVETGLNLLGLVGIYDPPRRETQPAIQECSTAGIRVHMLTGDHPSTAAAIAREVGIIPHDMGVFSKEVAASMILKANDFDKLTDEEIDALPELPHVLARCAPDTKTRMIEALRRRNAFMAMTGDGVNDAPLASAAKIVLTDDKFNSIVAAIREGRRMFDNIQKFILHLLTSNVGEVILLICGLGFRDATGFSVFPISPLQILWINMVMRRPPHDKKRGVFTNQILVDMVVYGSVMGTLTLMTFVIVVYADNDGNLGHGCNETFSEECRPVFRARAAVFAELTWLILISAWEFKDLRRSMFRLNPDSSSAFSFTKDIYGNKFLFWAVTIGFFSVFPVVYIPTVNTVVFKHVGITWEWGIAFAALIIFVACIELWKLIKRQFRLLEGGAVVRGPFNQGDEESGRKFGHTMSFSSLKSWRSIGRKTTGDTAVSRSATQSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3F3</accession>
    <name>A0ABR1X3F3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidophosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_066809225.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042285"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47203">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47203:SF1">
        <property type="entry name" value="HYPOTHETICAL BASE EXCISION DNA REPAIR PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="2">
        <location>
            <begin position="2"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="37961" checksum="2C2334055CACDA46" modified="2025-10-08" version="1">MADKMLQALVDKFGVSEEGTGAGSVNWNNIRIAAYDDVYQQLKSGGLGANKAKNIQAILGMVYDENMQRRAAYIEEQETGKEADVICASSKTKGQKDLEILRADQKKLNLDFMHDMTKDEALHHFVRYPGVGVKTAACVTLFSLQRPCFAVDTHVFRMSRWLGWVPQKTNEDDTFRHLEVRCPDHLKYGLHQLFIRHGKTCYRCNDKSFKGTEAWDESICPLEHLLDRFSKRQAKPKELTKPENQGKAQGKKSKTRGRGRPEIQYMKSSTTNDDDPDEGGVEAPSEVQAIDEGDESVIINANTAPHGAEDESNINDNQTEDESELSELDSSDISDIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X425</accession>
    <name>A0ABR1X425_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kelch repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673013.1">
        <property type="nucleotide sequence ID" value="XM_066809395.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042455"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011498">
        <property type="entry name" value="Kelch_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435:SF4">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07646">
        <property type="entry name" value="Kelch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="158"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="415"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8090119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="576" mass="61556" checksum="A1BE4855C4C78A33" modified="2025-10-08" version="1">MESFAKLKRRTTDLMESIPKNMPAMPQMPNMPQMPNMPQMPNMPQMSMPQMPNMHLKQSGASGPSMKGTWQHIELPPLPRSSHSLNVVGGSAYIFGGEAEPNKPLDNEMHIVTLPFSSAPADYYSVPAQVSAKTQMPETPLNTVGEVEESAAAAELREPLTDVETPASSEANPLSPTAAEKGKAKGLTHTEVPAPRIGHATAVIGTRIFLFGGRADTSQESTLDEGGRVWVFETKTHTWSCLLPASITGGITTDPSTVPAPRAYHAAAATDKPREFVGIKPLRRAESWKDWAEGDSAAVGIPQRPIPGHIAENARDEEDLDAGFGTLFIHGGCLADGSRTSDVWAFDPRPGGGAALAVAKSRLYRFGGFDGESELGGQLDVLELGVDQFDDRVSRGEVSVVARGDWVSLVPPTSPTLQGNTAPAETSTPLVPTQDPHPWPGARSVAGLQLVLGSQGREYLLLLLGERAPTAEGHEAAGAFWDDVWAYQVPPQGMTAASLADAAWRLAGRKTGEGRWTRVTPGPYDDEVDMDHQGPGARGWFAAANMGDLEEGGVVLFGGKDEANRRLGDGWIFRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4A1</accession>
    <name>A0ABR1X4A1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673142.1">
        <property type="nucleotide sequence ID" value="XM_066809524.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042584"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539452" evidence="2">
        <location>
            <begin position="18"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="460" mass="48383" checksum="0E0076AFC3ECDF8A" modified="2025-10-08" version="1">MLVPLLLALPLGILGLAMPPRETASPGLQPRDAPPVVQVMTMTCLLPGEEETSSSSSSSSTTSSSSDGWSWSPDSSSSMSSSSTSGVDDCWYWGNCSSSSAPYPASSASSSSVPDWCELFGWDCPGSSSSWYWPMPTASSSSVAACDEYDPYCSYTASATGNPWSSAAAPPPSPSPSPTPSACDPWAGEHCSFFTIQTPPVISVPSSTSDWFAASKTSRPFVPSPGRETTIRGTGSASFTTLVSSRDSSSAVPASGSDSSSSFSVTFHHSSHHQESTRTTKGVTTSVPHHILPPMIGDLSQKQKRAAPPPPPAPAPRNANGLYKRPSSDRIRNVRAVEKRWTETIVIGVSTDGTPVYTSTEYPAADESSSSSTSTSFFSASGGGAVVTPAPQWISVSPSSSIRCDDTFCSDGSSWCMYWAGLRRGMRLRGRCRGGADDYWDLLRGVIEVERKGGMGEGVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4N5</accession>
    <name>A0ABR1X4N5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arrestin-related trafficking adapter 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673213.1">
        <property type="nucleotide sequence ID" value="XM_066809595.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042655"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF174">
        <property type="entry name" value="ARRESTIN-RELATED TRAFFICKING ADAPTER 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="463"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="847" mass="94375" checksum="E37B8F50DF8CB9C7" modified="2025-10-08" version="1">MTESEDHYLRPDHYSHPLTGNVYYRPRHHLSNRPPTLPVPPIRPRTRRPQSIHIVSYPSGYIPPELRPVNYPKPKRSFRGDKEQTRADRQPKSPKSKHSKRAAFERIFAPIKEHFSHYVATDSASTRSETPRPSTSSCPRTLRPIPEVSTRPMSMVSVPTIGASGMPSSTMVDNRRGPLLNAALQNSHRSSLMSMRSAKNIMSSVTEVPKPVASGSGVSCSIVLAEPNVFLTGFEHDGHPRHETANSTALLRGKLQLDVSKNVKLKSVTLKLVGKARTEWPEGIPPMKVEQYEEESLRTQVLTFFHAMHETWETPYGNQCNYSIRGNTGSSANLAAQSQLSLSIKNQSRGNLTAKEYKRLSLQSVQQRSFGKGESPGVNAVQKGYKVFYPGTYEYSFELPIDHHQLETTKLQFGSVKWALETVVERAGAFKPNLHGSKEVSIVRVPDQLSLEMTEPISISRQWEDQLHYDIMISGKSFPIGTKIPIAFKLTPLAKVQVHKLKVFVTESIEYWTNDRRVTRKDPGRKILLLEKSAGKPMDKQFENSEINILSGGELSPDERHEARVAAARRRSLEASRSHTAPHPLPDPSDNLLGDLDLGLESYWGSTEIEMNVQIPTCDQMAKDKTIRLHPDCSWKNVNVYHWIKIVMRISRLDPEDPAGKRRRHFEISIDSPFTVLNCLEPTPMSVEPSPLAPLPVAHLGSQAQAGGTQSVQRQQGAPQQPPQAPAVSRPIHLMRYPSFNPPAFEEDEAPPPLADLPPQYDAVVGTPSVDGLADYFARLADYDDGDSDSGDEDFGHPSRITGRNGRVNVANPRTPGGRSIPSRSVEIQRPALPTLTMAGALTQRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4V4</accession>
    <name>A0ABR1X4V4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673283.1">
        <property type="nucleotide sequence ID" value="XM_066809665.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042725"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="179" mass="19817" checksum="8CA7A2BA4EA57612" modified="2025-10-08" version="1">MSGLANNDVGDKLVEPAAFDEHQEFLARLYSLRLAEDAPDVPTTDEHGTPMQKLKRRMGDTTKSAFMDNDNSGGEDSGKKRPFGTTNRSARTKTPPKKALNNEDNDRENISGVTHNVPVKEKKHIDTSKSSTGRYSGKKSTKKKTSGDFPNPYFDYGYDHHAGVKGTKRLTKIHLLAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4W2</accession>
    <name>A0ABR1X4W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673359.1">
        <property type="nucleotide sequence ID" value="XM_066809741.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042801"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="636" mass="72152" checksum="577AFB5CBF547FC6" modified="2025-10-08" version="1">MPSILDRFAGSTKPRSGHNTSNTGHSKSSSRHRESENPAQKTRSSHSKRHPDQTVFECDVQDPNSSTETSQSGHQNKVVQHRGNTSSPPEPLDAPKKKGRKKSSNGSRSHAKSGQDHDKHQEAEKGKNHTTPSDKKHRRGHKSDDRAHRKESNTCRDPTISLATATTLPDESQAVTAIRCGAMRTVRDGAPGKEWAQIMGLYALFFESENPLEVKANEALAKNYGLSWTAWRPMKLNSRHSSLEVIDGEETAICRFLSVRADNTKDLLIQTWLWQAAMPFHHQSSREGRLQTFPRSSEGCSRRFKHYDTWLRFCNLINTISLDGYVVVALSDNKSKIPQVVGAIEIEADKLAELEHYQKCFKEKLLKSDRCAPVWCLRDFAVQDGLQFEALESNLMECFTQPAEKEPVARVTFMHFRNEMTWWEHYGFHCRVYEQDFCYATWSARRVIKSGGALPLSYAPSGLAESTSDGTYVMRFLEGPDDTRHYLDSGPGHALVKSTLEVDDDIPIRAGDVYVLETSDPEKYPLPCWDLLNLHYHIQKVTYNFKARGAQESLSGGPPPDVDGDVLRARKMQSPSTNLWADDVLEAVRDEVISEEDGWKWVIGLEELEEERQLRRRHELAELMEDLEEGEFEDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9M7</accession>
    <name>A0ABR1X9M7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_000030</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674118.1">
        <property type="nucleotide sequence ID" value="XM_066804345.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037405"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="16"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="508"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8093345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="534" mass="57743" checksum="716C3CAF9248BF67" modified="2025-10-08" version="1">MKLPTFPKIYNIHFVAIIATLGGMLLLSLPHHGVKVASFSSFGFDISSMSAIVVTDQYLDYFHKPAGALQGAIGSALAAGSVLGSAVAGPISDKIGRRDSVMFACLFWLIGTAVQVACQNAGTLITGRVINGFTVGITSAQVPVYLAEIAQAEKRGSIVIIQQLAIEFGILIMYFIGYACSKIPGPASFRTAWGTQFVPCVLLMIGLPFLPRSPRWLAKVGRRDEAIEVLARIQAGGNIRDPLVVAELEEIETTLQAEREAGPGLRKFFRNGMWKRTMAGVSVQAWQQLAGANTIVYYLTYIAGMAGLTGDVAMITSGVQYAVFIIFTGVMWLFIDKTGRRPYSSMAPSAWAFGIGGNPNVIFKVTSGHAANTVITFSYLLIVVYALTLAPGCWIYAAEVWSLGTRATGMSMAALSNWVFNFALGMFLPPAFANIQWRIFIVFGVLCIAAAGWFFAFYPETCGKTLEEVELMFAKDGPAPWKTRKGESRLTAEIQAVVERKTYDEPKAVEVADNHAGPETPDNKMVDTSATKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAI4</accession>
    <name>A0ABR1XAI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Telomere repeat-binding factor- dimerization domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000370</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674458.1">
        <property type="nucleotide sequence ID" value="XM_066804685.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037745"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013867">
        <property type="entry name" value="Telomere_rpt-bd_fac_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052833">
        <property type="entry name" value="Telomeric_DNA-bd_trans-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47807">
        <property type="entry name" value="PROTEIN TBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47807:SF1">
        <property type="entry name" value="PROTEIN TBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08558">
        <property type="entry name" value="TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="754"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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        </location>
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        </location>
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        <location>
            <begin position="912"/>
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        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
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        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
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        </location>
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        </location>
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        <location>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1739" mass="188382" checksum="62DDBD89EECD0366" modified="2025-10-08" version="1">MDEALEEALRAAAAAEHPPDHQALLDALAAMASEHTTTPPTSHDESHHHVPEHELGPDIFDLLRQGQHHEPEEAQQQPDNDATSATPAPMATDLHPAPSSESRPQSTEAQEQSPGTATAATVVPEEADEDHQEILDALAAIFPSEQPTAPTNSEEKDEIKRESPAEEPPQSPLKRMRSPEDDATADQRDEKRVKTDAEHARELAEELQRIFQSAPSNTAHDPMDTVTADETGEPGDHSMLDADAHIIDHLNGHFGEQETHDLPNDVLDGFHSDFVLEGLDGENTLHSEQNGTPDLTLSETPTHKRSIWDPNPKHFTRQMHYIPTLGTVAYDVLRALSERSFETVIAGINPKENGEETEVFKEYRKLKSFFINLREKLNDEFPLLYPDQLDIVDTGEQEIIRVANLATICSSIFGANELGWPDLDSNFLLAFVPKSKPMTSEVADLYIGLKTQMYLDLLENEKDSNRESLLKRLFVDGVESSLKQRHPDVPLVGAEKDFLANCNARKALLLEESFDPARIVDLKDQKYPYDSFLQSINVYISNCIETIENLATRRNSISFDMENFSFDDGLDGHDLGDLETIMAEAASRAAQAQVDEKESNGADIDELAALLSDGITRNSQQQQAHPPTSAASGLSPTALALEESALRAKTLALDSIQQNQYRPTVSPQPSSKPTTYHNPQQHQAQPQQPHPQYYQYNQQPATDAQASDKVTSANGVMLPPNQTDSTPNLYERARQAAAARSSNHARREGSHSTRRPWSADEEKALMMGLDMVKGPHWSQILSLFGPNGTISQILADRTQVQLKDKARNLKLFFLKTNSEMPYYLQCVTGELKTRAPTQAARKEAEEKARLNSQEEQERINGIMALGSMQTNGAQRPNPALVGQRSATPTQPTQGGFKRIQMRTEPPKANRLHRLQAGSQQDNRPSQSGILRRPPSPTSRKAPLHNRKRRSIPWLNRMQQQGLPQSLQQHHGLPPAPQQQSGLPQSQQQQRPVQSTLQNPKPQQHPPQYQQRPQPQPQPAAQGHTQANLQQQPQRTQQPVQAGTAAVNTQQTQQQRAVQPQGQLRQPLGATQAAPRAPAPGQAPAQTAGQAAAQAPCPAQYAGASQPISRPPQPQQPSSQSHISTQQPNVQQPVIKREGVPQQPAQSHSGNTQPAQQRPVQQPSLPQQPGHPVNTQQPAPARAPPQSAPSAASHAPQGALRTPQANSQPNLPNIGHVPPRAPLQRAPQQAAPQGPSWVGPQAGQSTSQATTPAVPRTNPQPSAQSTPQAVHQTAAQPTSQAPARVGVQTTAQASTQAAPRAAPVTANQQPVRAGPQNLPQAAARPVPTTASQPLSQAPRPAGPQTAAQAAAAATRPPTQQALPQASTQPSRPIGAPGVPQAARPGVPQTPAQPVSQAAPRSTPQAGPAAAPRAPSQTQSPRLANPQQLPPAQAQAQPRPQPQSQPQAQPQGQPRAQPLAQPQVKPQQPPQPPPAQQQQTQAKPQAAAQPQAAAQPQAAAQPQAAQTQQRPPPPPPQQQQPQPQARQPPPPPPQQPQQQPQAPSQAQPKAQPQAQAQAQAPAQTRSPVQPQAKPQGPSQQPQQPPRQSPPQPLQNPLPQKPPQQAPQQAPQQAPQQAPQKSPQQAPQKIAEQAPQRPPQQPAQQQQQPTPPPPPPQLSQQTSEQRPQVPASTPATTGPQPEQQAKAEPAKEGELDHLFFLKEAMEREQQDARDKEARDKEAEALRVALLAIEGAGGGSNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAK6</accession>
    <name>A0ABR1XAK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674407.1">
        <property type="nucleotide sequence ID" value="XM_066804634.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037694"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39596">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39596:SF2">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G17550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="832" mass="94310" checksum="E20F3D54A418FB03" modified="2025-10-08" version="1">MSMNSRYSVSRAYTHITSAVNGCCFAVKLCSREPNRATRFRHFLDGVENEPIDVNHVTEVIFWMAKIQRKKGIGPQGFGRWTANLLPDMVALPTVEEAVAMAPELRACQYRLWKLIDVCDRKESDLPEIIKALRKLDREHDRQQDDYFHQQSHKVCLQNIHQKCSPTKCDVPHKDTTHPIQAHKMCSQNIHQQCSPNKCQETHKDTTNLNQAHKACPGEKCTKLQFNHELLITAVYQGRDTTWGFEEPGSPLKLLQPSANYLAISHVWADGTGAGSGDFGKVNKCLFDFFCDFARKCECDGIWWDVISVPRESKAGAKALKRMHHNYARAKYTLVHDSHLLEVPWKDDGTPCLEIVLSAWCTRAWTALELKESRHMGFLFKNGQQRGQHDGFVIKDLDRDILAKNPESVFRPHWVATKLISQLRKPVNDVGDLLSILSPRSTSYVRDRTTIAALLVGLPSFDSTAGETDDEEPMEARDALAKMSGKSATLGAIQETLSSDDPKETGSLKWLRLRGKPTDPAPMLPENHQVDSESLIAAVKVLADSSRKKKKAVIVGGTPKLPVTMAIGKNAAKYLVSKDITLEPQQIDKLLEVFSKPSEVSFIGLTMLADMYTDNKKYEKAIHLYKTVNNRYDYIPPDKKNLLDAWRKTNTTVKRADKNDKRDAAMYRLYLNASAELSMFYTRQYMFLEADTTYRGALAEFGTMPSHNEAFRIGWAQRATQTFRKKSSRDKDAAGCYERALKRFNALFHQKHPIIQMTQLHLGVNYTLQEKSKEAEHVLRHAELGVEQDRGGVPEGDHAFLGLVKYHLGNVYLKDHKLEEAKTKLEEAMAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAQ6</accession>
    <name>A0ABR1XAQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674452.1">
        <property type="nucleotide sequence ID" value="XM_066804679.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037739"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="38084" checksum="3DAE7279AB637F7C" modified="2025-10-08" version="1">MASKTRLLAPTAASVYAFHIPNNQLVLTPWNSTCNLPIPPRGKPGKRPRYSLSALEWDNERNVNDRLHTRGCDECSATLRRHQRAQEEHVKERVDAARKLHSSKDANHRASCTYCRIIWEVQTHRKEKEAHQEAIEVRYETQESEPYAPSNKFRRGRSPRVRFSNRDKIRIISALGDPILEEETSHFSTAKVSDALSTTTYYRRKRIYRRARLAGLKLGAVVSKAKYSDLQPNTVTVPPPVANISELNSLKRSIYFRRQKVYRRARLAGLKPKAEPSKEEHRDPEPDTATTLPTLPPATKRHTTSNIPKLRSKRKRALSDPVQEDVKFTEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB40</accession>
    <name>A0ABR1XB40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1763-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674570.1">
        <property type="nucleotide sequence ID" value="XM_066804797.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037857"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="15487" checksum="CC851FECBF0ECE2E" modified="2025-10-08" version="1">MANLEIIHAYRHLYRGLLHAVQYSKPARYVACHQLRAAFRENGAVFDSKGVSRTVAFLDAAARSRGPEHKVLKNLLMIAYHRVHDRPQSWRHVNLEANSRKKETEFTKHARATAYKHYDMTVAMLNKSMGLCLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBH1</accession>
    <name>A0ABR1XBH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha,alpha-trehalase</fullName>
            <ecNumber evidence="3">3.2.1.28</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000617</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 65 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674705.1">
        <property type="nucleotide sequence ID" value="XM_066804932.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037992"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="entry name" value="Glycoside hydrolase, family 65, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="GH65_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005195">
        <property type="entry name" value="Glyco_hydro_65_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005196">
        <property type="entry name" value="Glyco_hydro_65_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11051">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11051:SF8">
        <property type="entry name" value="PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03632">
        <property type="entry name" value="Glyco_hydro_65m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03636">
        <property type="entry name" value="Glyco_hydro_65N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046498542" description="alpha,alpha-trehalase" evidence="4">
        <location>
            <begin position="18"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 65 N-terminal" evidence="6">
        <location>
            <begin position="53"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 65 central catalytic" evidence="5">
        <location>
            <begin position="410"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1003" mass="109941" checksum="4CC9F1BD71F01D18" modified="2025-10-08" version="1">MTRLLAPLLTASAVVSATPLNLPANWVSWDDATWTLKSTVPLPGTFAAWAPQSNGYIGVAQGSLGPFFELSRYNDSEGWPSYSKPRRTFATTSGFWGSEPSTDELDPRGESFISGLPHFTDLLVEACGDLLHGSTDLAEISDFVSELSFKEGIATWSYLWQPPSCMNNRTISIKYESFLSLATRQLAAVKLSLASDSGLDDVRIIDKLDGRSALRTTPARTNYVPGASEVVSAVSPTGVNSTTAYILSTIDGDLQYNDTLATHDGSNLSAYTHLFSMAFLKDTTNSTSSKIYAIRPGSKSAEIRKYVGVASSDHFGDAAEVVAVNVAKKARVQGYDAARADHRQEVSRLMDNHVVADFRDPVTGEMPEDHLIQTLQITAISSAYYLYTNLLPWDSEVDSHPERCVACNSLPVGGLSSQAYGGKIFWDAEMFMAPPTQGTHPRLARQFAQYRINRASEAKKNTERHALKAGSMLYPWTGGRYGQCYNQTGPCIMYQYHLNADIALSLLMGKNTSGDGIWFEKSGAVDAIDGVATGLSETLAFRDDTKTWGIDIMTDADEYYMYVADGSFTSSAISVILEAASNLRRQSGIPVDDKWVKQLESMAIPTSDDGVVLEFRNMPNSIISKQADVILSHYPFDYRRNFSTEKRRLAMDYYSVRQDPNGPAMTWGLYAIAANTLTDSGCAFWTFLVKSFQPYVRAPWYQFSEQQVDRPSVKDPLTGQDINPAFPFLTGHGGLLQTFTAGFLGLKVTDTNLVVLPSLPPQLHHFKAPIQFYNGAVVEFWMNQTHTNITRHDASLFDGLVPDQYGAADMPITIGRNVNDGDSYTIHLAINGTATIKNRAQHTSLNMAGNILQCLDAKTEDAYAPGQFPFAAADGYAGTVWQPTGSNSASLTIETTSLSPTRLKSVHLDFGMRPPKSVRVLLSNSSTFDDPKTTQEIVRETKIQITQPWKPDSPVVPYAGNITEIALADEVWSGKYARLQIEGCWVEDGVDATVAEFALLAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCK0</accession>
    <name>A0ABR1XCK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF974 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675204.1">
        <property type="nucleotide sequence ID" value="XM_066805431.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038491"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010378">
        <property type="entry name" value="TRAPPC13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055429">
        <property type="entry name" value="TRAPPC13_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055427">
        <property type="entry name" value="TRAPPC13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13134">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13134:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23647">
        <property type="entry name" value="TRAPPC13_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06159">
        <property type="entry name" value="TRAPPC13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex subunit 13 N-terminal" evidence="1">
        <location>
            <begin position="16"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Trafficking protein particle complex subunit 13 middle" evidence="2">
        <location>
            <begin position="264"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="39755" checksum="13867918EF7E17F0" modified="2025-10-08" version="1">MSHQRYPSMDPVKEPHSVSLKVLRLSRPSLVAQHTLAAPSELQPTTGAAPDDLVPASLAYRSTAGTNPDPFLLTPILNLPPSFGSAYVGETFSCTLCANQDIPPEPPATAQTPAKVQPQKKSIRDVKIEAEMKTPGSASAQKLLLGPHGDDGTPAATAEATGAAADAAGAGGVDLEPGQTLQKIVNFDLKEEGNHVLAVTVSYYEATETSGRTRTFRKLYQFVCKGSLIVRTKVGPLPYNTATTRKVPKPAEDDENKQLRQKRRWIMEAQLENCSEDAMQLERVVLNLETGLRYRDANWIVSESPRPVLHPGEVEQVCFVVEEDGKGSAVVEDSDGRVVFGVLGIGWRTEMGNRGFLSTGKLGARNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCR2</accession>
    <name>A0ABR1XCR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001176</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675264.1">
        <property type="nucleotide sequence ID" value="XM_066805491.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038551"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF88">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE PROTEIN CTL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="656"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="697"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="16"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="105"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="219"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="761" mass="84060" checksum="F6C90ECC07364EC5" modified="2025-10-08" version="1">MFSEYASKFLAQSQSRLSNFGQTDATGEPSGRQTSDPSSRFSRHPTRSAYHSRLGNPYQPSGSRFGFGSRYQGGQDAAPLFHSALNEFQDEDEDDLREAADLRALQRSRRVFVSSRIDESSASENEQSRGSLDRSGERDTRGYEDRGRPMGIKSSWNGESSFKDFKDRTGKPKRLDETAASGKRKSERANSDSSDGGKMVDIGLESEMLDNEVPEDLLQETPVDTDPPAFQQFKSKSGGWKGTASSKRENNLEHDPRLMRETILEEEEPPEETIPGTANIEYHHELFKNDQFWAWLYLIAIASLFATFVLVWLHTSTPSRKNPIGDTIYTVLYKSYYLLAVDTLVAVIVSLVWMAALRSYVRQLVGLIIIGSPIVLISFSIYTMVLSFQGPDNGTRLQDRAMRYSSIVPGVAAFVYVFLILKTRDTITRATEMLSFTSRVLSANPALVMLGFCALAFTVGWTWIWLSMFTRVFLGGYFSRSLSSYIIGAASWWLGVFFALMYLWTISISSNVVRATVAGTVSNWYFHRNKQPPAPSNAVVGEALQHATNSTFGTICAATLLALAIRLPLIVLPHRASKTVGFLLNRYTPASVFLLTNPLVITHAAIHTLPLMLSAAQLSRMQFLDSDNPTNTLGLGHLRHANRYSTGLMPYRLAKFLLHATRTVVAAGLGFAGWVMTARQLEIQVPQGAGIKGSAYAYIVGLVAGAIGYSILGALEGIMVGILDAALICYGSERRMGSGRMGYCMEAANLFGGRNESRDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCW4</accession>
    <name>A0ABR1XCW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heat shock protein 30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001147</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675235.1">
        <property type="nucleotide sequence ID" value="XM_066805462.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038522"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15239">
        <property type="entry name" value="7tm_YRO2_fungal-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043476">
        <property type="entry name" value="Yro2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF1">
        <property type="entry name" value="30 KDA HEAT SHOCK PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="31817" checksum="67157592D957EB37" modified="2025-10-08" version="1">MGLILRSNQALDINPPAGNEAFSVHGSDWLWAVTAVYVIIFLAFYAASFKPFSGEKIFHYIFSVALLVGSIAYFAWASDLGYSVITVVNSKPTSSWTRQVFWVKYVYWVVEFPAVILSLGLLSGVSWATIVYNVFLSWVWVVSYLISAYTTSNYKWGFYAFGTFAWLMLAINTLGHGGNSAKRVGLTRDHSVLSGWVNLLWLLYPIAFGLSDGGNKIGVTPAAIFFGVLDVLLLPVTSIAILALSRKWDYGRLNLAFTRYGRVHDAGSFPEKNAPAAAPAPGVTTAQPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDD8</accession>
    <name>A0ABR1XDD8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pirin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001336</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675424.1">
        <property type="nucleotide sequence ID" value="XM_066805651.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038711"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="3">
        <location>
            <begin position="83"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="4">
        <location>
            <begin position="228"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="353" mass="38443" checksum="EB0C415CAA1B479C" modified="2025-10-08" version="1">MKFVSLSISIAVAILSIVIFRQHLFEFASTSLKALNTYYSDITTPTTQPQSPDDSSDHIANMSVSRAIQKVFLAVETSEGAGAKVRRSIGTPQLRNFSPFLMLDHFSIKPGAGFPDHPHRGQGDHHDFAGNKGTIETGDLQFMTAGRGIVHAEMPRQNPDGSANVGLQLWVDLPKDLKMCEPRYRDLRAAEIPRATADEGRVHVKVISGQSVGVDSVKDLAYTPVWILDIEVQPGGKLAQPIPAGWNAFAYVLEGSATFGLGRTQQSAGQYHNVVFDRAGDMMNVEVPADAAGPARFALIAGQVLDQQVVQYGPFVLSSKEEVYQALMDYQTHSNGFERADGFQSEIGKTMAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDU6</accession>
    <name>A0ABR1XDU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675547.1">
        <property type="nucleotide sequence ID" value="XM_066805774.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038834"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="15"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="187" mass="20714" checksum="CDD514E14306E160" modified="2025-10-08" version="1">MSPDNRTPKPVAPTALCHIMIDFYLTALNATISHQTPTLCFLTYDHEHHRLALIADDNVSPKDPAKPQVGLHHVAFGFPTLADLVDAYEYRETKGIKPCWCVNHGVTTSMYYADPDGNRVEFQVDNFDTVDEAKAYMAGPAFAENPIGVEFDPDAFVRRVRAGVEENTAIKARPDVGRRTAVDINLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XES7</accession>
    <name>A0ABR1XES7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675856.1">
        <property type="nucleotide sequence ID" value="XM_066806083.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039143"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF31">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN YCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="294"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8095083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="547" mass="60333" checksum="F8A90457E7CC7DA6" modified="2025-10-08" version="1">MCTPGMLAVTMQPKPGLPPAQFHEWYNNEHGPTRLRIPAIFANGLRYRAADDQQPDFLAAYDVTRMSHLETDTYTTLRANRSPREAETIGQVDVTRHFWDLVSEKKSPLFLPIEQLTDDEAAGLKLVVVELGLKDHPDAETELLKWYNEEHAEMLSKVPGWLRTRLFKTSVLDTKGGAKTMFYGVHDYTKENGLGGPEHKASMATPWRVKVTDNYATLQGRRIWSLFYTFGPAPRDLASLSELPAATSTFQSADGKTKTTNNNSNPAIESFVTLPSDGLVIPYRLEGNPDPKAPVIAVCNSLLTSLHMWDGLVSLLKAQRPQYKILRYDARGRRAVPHPPKPATLEMHADDLAGLLAALRIPRLAALVGVSMGGATTLKFALRHGAKVDKFIACDFNAASSEANTSAWKERIALAESTVTLDDDKKTVPGIQKLAGATVQRWFHPNTGPETVQWMTDMVAANDVEGFRYGCQALWDYNMKEEMRQCAVPGLLVVGEGDGKGALVKAMHGFRGNLGEKGAELAVVPETGHLPMAENPQAFWDKVQGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQF9</accession>
    <name>A0ABR1UQF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_015363</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660562.1">
        <property type="nucleotide sequence ID" value="XM_066819677.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052737"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052094">
        <property type="entry name" value="Pre-mRNA-splicing_ERAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="18"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="118"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="127"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="241"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8061142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="280" mass="31606" checksum="77C5CA0577161461" modified="2025-10-08" version="1">MEKSELLALAREYAKTEDLFDLLGIDALKAEDQAEVRRAWRKASLKYHPDKVGGPSGDGFNDTMKAKWELLERAREILSDPATREAYNSARSAILIREQQRAAMDAKKRAMIEDLEARENGTAVKRKRDDGKVAETEAEKQAAMERGRKRREERQRLMREAEERERLRNPTIVQEQKAPAHPQQPPQGDSGESKPTTSERDGQYDARIADIEKRLEEVRQRKAAKKARKDKDASGIVVEEPAAAAAGDDATAAPKPAPKRSAKMEALLKRLREDKQKQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQM9</accession>
    <name>A0ABR1UQM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_015444</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660643.1">
        <property type="nucleotide sequence ID" value="XM_066819758.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052818"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF3">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="97"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="192"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8061223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="506" mass="54719" checksum="BBDB71A476C67626" modified="2025-10-08" version="1">MASQHSASAEPESWQDKVARKRWSRQNDIPTAWALPESVLDSLPALCDFPSTRLNLIAKDVPWLSGILTEREIEITESHTVTSLLEGLASGTFTSVEVTLAFSKRAAIAQQLTNCLTETFFEQAEKRARYLDDLRSKGGPLGPLHGLPVSLKDTYQVEGTQACIGAVALLGRTSTENSAMVDLLLDLGRSWSVRIPSLCCGTYGFKPSSRRLPYGWQVMPLNVGIGAIVPSAGALANDVTALQIFMQAVVDAKPFAYDATAIDMPWRRTNGPPRPKKLRLGLLPEDPLFPLQPPVQETIKSAVRILESNGHEVVRLDAAECQVAAANQIGGRLLALDPTPASIIASGNEPSVPSMAMFAEQAARIGWDFIPTEVDAMDGLGQFGALQNERVDIAESWRKIWAKHELDAVIAPPAQSTAMEHDQQGWPAYSMFLNMLDYPACIIPFGKAKGNGTSLARGPCHGTPAYKPDVAEGAPCSIQVFTNGMRDEECLAVAAVIDTCLKDASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTA7</accession>
    <name>A0ABR1UTA7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660726.1">
        <property type="nucleotide sequence ID" value="XM_066818538.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051598"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="257" mass="28142" checksum="E61E9DF7C0B5675E" modified="2025-10-08" version="1">MVSSKGKPTDPELREELKEKIKAEPNKSGGGEGQWAAWKGAKLAKEYEKQGGDYENAAGSKNQPKKGAPQAKSEGQKEDETLVPVNAHIDGFLLFLLPSATLALPLELVIDSVQPVALEKGSETSGFETTLCRKIFQFGVEVTHKRFQETKFARLDYLDLTNVFVLVPSNEYQGPERVQTTGRATGMCQSQRFKCQHPESRRYPFDICRYVEPAETSFQLGRDIGKPVGPVAKFSEQDGGWAAAVSRTATGASVNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTY1</accession>
    <name>A0ABR1UTY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014481</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660983.1">
        <property type="nucleotide sequence ID" value="XM_066818795.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051855"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF4">
        <property type="entry name" value="HYPOTHETICAL CONSERVED PROTEIN (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="35"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="66814" checksum="F1E3EF859786D20A" modified="2025-10-08" version="1">MAVLHPRPAGIFLAEPVPIHPAPSKLFDVSVKLKASPKDSPTTALDPKPSEDLECRPATKSSPRSNQMSLMPKGNSPPECKCESVGLVCEGYALPKAPKQAVPPSRQLLPRIAQAGLASKAAALLRSATDIAPKLPMQPGLGFDASGDDGWYMALFRERVASDLSPGKGANFWIRSSFRDSMTMKAIRHSILGIGAYSRALIDLKTDYPWIKTADRPWWPSSIQNRHHQAALDHHIKAISYLQQDIRNNNVDDRMAMAANLLLIVFENMRGNYHVAGNLVRSGIKVLNRMGQRGSHVFRRDGLHILAAFHRDGQCPVPHGKSAYHLLLNDDSPTSDDEENFPVSCLIEDTTPHSCMEARAIWDRILHSLAGFYAKALWINLHQDFSVDKDGLAWEQALYLSRLQEFGLGLSTIVAVERNANTARPLTFLTIHHLVATIFTSCCLDPSEAAYDSFASEFDTLLSHIQAYLEIPSTFTIGFTNEVGILPLLAFVAAKCRLLHVRLAAIDLLMNYGWREGPWDGVSLARAMEGLMNIEGQNPPQAGQDAGQGDGSFAFAQLPSADTRYAWTNMFWDYETQEMTMEYTKLLPNIDGGLDKKTLTVSWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUX0</accession>
    <name>A0ABR1UUX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribose 5-phosphate isomerase RpiB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014826</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661328.1">
        <property type="nucleotide sequence ID" value="XM_066819140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052200"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="entry name" value="Sugar-phosphate isomerase, RpiB/LacA/LacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011860">
        <property type="entry name" value="Rib-5-P_Isoase_Actino"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051812">
        <property type="entry name" value="SPI_LacAB/RpiB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004051">
        <property type="entry name" value="PRK05571.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02133">
        <property type="entry name" value="RPI_actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43732:SF1">
        <property type="entry name" value="RIBOSE 5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43732">
        <property type="entry name" value="RIBOSE 5-PHOSPHATE ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="Ribose/Galactose isomerase RpiB/AlsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="163" mass="17091" checksum="7880A7EB781F4C8D" modified="2025-10-08" version="1" fragment="single">MTSINKLRIAIGGDDAGFEYKAKLAADLAADPRVAEVIDVGPNSSSDKTPYPQYAIAAAELVASGKADRALLICGTGLGVAISANKVAGVRAVTAHDSFSVERAVLSNDAQILCLGQRVIGLELARRLTKEWLGYTFDPTSASAAKVQAINNYDMQRSHTVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVB0</accession>
    <name>A0ABR1UVB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RTA1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014971</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661473.1">
        <property type="nucleotide sequence ID" value="XM_066819285.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052345"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF34">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="314"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="314"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="410"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="424" mass="47563" checksum="26B280AF7F6F4B75" modified="2025-10-08" version="1">MAYSDPVPYSLYVYKPNEVLPIVFAVLYAISAFFHVWQCHRYKAWRVLGLHPLCGVLFVIGYAARAWASTGTNYLYDESRPANLGLFIISQVFIYCAPPLLELANYHILARLFYFVPYLAILPGRRVMGIFGGIMLFVEGLNGLGAALGTNPKITNTSIGTGLMLTANATQVAVILTFLVLASTFHYRCETRGASTGMLNLRNRRGIRKIMITLYVSMVVILVRCFYRLIEHTGDNHIDYKDYYFYIFEAALMLVNSALWNVFHPGRFLPRTIQTFLTREGSQVEVAQPYDYRQPWQKIVHLFTMCVLYRKDDGCPSPSHKERSSRPRTGGGGYDSARQPPMAYESSPSSAPAAPGKYYANGDGGGSRDTSTSPVEIFLNILTLGLYGALKPSHKNRGSRSFQELGEYPLADRHGSHERLRGPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVC8</accession>
    <name>A0ABR1UVC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661446.1">
        <property type="nucleotide sequence ID" value="XM_066819258.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052318"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="66" mass="6944" checksum="D77959554776D2E4" modified="2025-10-08" version="1">MTSTPSTPTSGPTGLKPRGEINQQAVVVGFVGGILALSILVSIAALVWTRKKRRQQGPELRGPYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXP3</accession>
    <name>A0ABR1UXP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014922</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661424.1">
        <property type="nucleotide sequence ID" value="XM_066819236.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052296"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF80">
        <property type="entry name" value="GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046655348" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="26"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="380"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="527"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="707" mass="75835" checksum="35963EBCF43255AA" modified="2025-10-08" version="1">MMLLPSHCKLLLVLASSTLLGSAQGHPHARRDDHETIGGTADNTYDFIVVGSGPGGGVVASNLALAGHSVLLIEAGRDASDDLSTSIAALSYPGTDTLKWHFFVKHFRDDQEQELQYNHLTWTLPNGSYWVGSGARAPEDARLDGVYYPRGATLGGSAIVNAMGTFLPNDADWDYVADITADDSWSSGKMRSIFEKVERNHYLPKGTQGHGFDGFMDTQLGSPDYYKRSPGALSFLGAFAGGLLGRIARPLGASELLPLIGRDPNCEGSGRDFATGSFGLPIHTTEFGKRWSPRDLILSTFNAKNKDGSARYRLKLQLESLATRILFDNDRTSSKPQAVGVEFLEGSMVYGASWKHDTANPPKGMPKRAYARKEVIVSGGTFNSPQLLQLSGVGDRPHLRSLGIPVVAHVPGVGRNLQDNQELPVVGHGPAAFATAPDPASAAYNCTLGAPGDPCVAAWWRGGGPYAGAAQGNSECALLRTGHSPDGRRRDVLTFSPPRPAFRGFWPPTDQTDPGLFTDPPNAVSRSMVRMSSRPPSPKAGVRITSRDPTAPPEINFEHFPGGLDDEDLGAMLDTVAFVRRVFAAVPPPYGPVMPTEPPCPAGVLADGHCRVREQDAAWVRSQAFGHHATGTCRIGNFSHEEDEEEDVHGLGKDDPLAVLDARFRVRGVRGLRVVDASVFPRQPGAFPVLATVMVGQKASEVILEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYQ4</accession>
    <name>A0ABR1UYQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661512.1">
        <property type="nucleotide sequence ID" value="XM_066819324.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052384"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045751627" evidence="2">
        <location>
            <begin position="28"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="342" mass="36117" checksum="03549E2E12719B1F" modified="2025-10-08" version="1">MTQSHASPSAATVVLAAAVLFSGNAQAYQGWPSSNTLVDGDAVRFSQQTWRQHLRHPDARGEYPVRGFDIAQQWPDVREVGGWRLAVNVSNSIPASEVQNDDGTGTSISLQGPEDVIHSILGDNSGDEQDAIVALGLRSTTWKVCVTIATDDNGDKKNATNGVSCDRLTPQCVADFEQAYADHFAATEDCAGHPPPTPASCGGTLDAASLRTIQYPIDAVNGTELYVTASDAAAQQQQPPRGGGNLTTAWHNDDAASRMWPVLVVWGWNHRATMGDDAAAAMRNKKPLAQLACIKATTSHARPAPTPTATPTVPDSSGVESSTPMLTGLALLTVAISFVLFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V208</accession>
    <name>A0ABR1V208_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661972.1">
        <property type="nucleotide sequence ID" value="XM_066816280.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049340"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="134" mass="14230" checksum="80360D42A9C8D7E6" modified="2025-10-08" version="1">MAVIEKSDHVQVATGVENRATKRDIDSENDSQRSDDEVLSTLSGGNLVEGYISYLPVIQFGFNLLATWDRVGLTLQLNLLNGGNSALIYDSLLSGVESCLVGPLEWLGGVCHVVFWLASMAVLGGAASCPTEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2T7</accession>
    <name>A0ABR1V2T7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012246</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662252.1">
        <property type="nucleotide sequence ID" value="XM_066816560.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049620"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032382">
        <property type="entry name" value="AltA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16541">
        <property type="entry name" value="AltA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047089437" description="AA1-like domain-containing protein" evidence="5">
        <location>
            <begin position="18"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="AA1-like" evidence="6">
        <location>
            <begin position="41"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="190" mass="20772" checksum="58FDA2287B8F0008" modified="2025-10-08" version="1">MQSFVIALAALLPLAAASPIGRRDDNKGCSAAAFHGFAWEVKNFDYHASYIFSTPAHQNSWGYVNFSLSNPALLYDVQCSADSSQLSDFFYGNIPYSCTGGPNGTTTQTTFDFSRPSGQLNISQTWVCSDEDPQWPSRFTAWGSVNLTLDCTDETTTNPNWKLGDVYSDREVKCAPSTVSLTPYQMAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3E7</accession>
    <name>A0ABR1V3E7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_012461</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662467.1">
        <property type="nucleotide sequence ID" value="XM_066816775.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049835"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF143">
        <property type="entry name" value="EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="14" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="17">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="435"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="4"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8065714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="476" mass="53033" checksum="0465E15C86073B6A" modified="2025-10-08" version="1">MKNCLLKAIEASPCGPTDTRCQCTNAEFVSHAEICIVTSCNVEQSLVAKNATQTMCGAPVRDKRVMYNVVSCTLMAISCVLVLVRLCYKKLCTTVELGLDDWFIFLTLLNCVPSAFINVHLLTRNGLGKDIWTLTPEQIEGFAKGFYAITICYFSEVFLLKLSILFFYLRIFPSKGMKRLLWATIVFDVLFGVSFILIGIFQCTPISANWTAWRGTTEGQCSNKSAIAWANAAVSIAMDLWMLAIPMSQLKSLNLHWKKKVGVGLMFFVGTFVTVISVVRLSTLIQFRGSSNLTWDYYGVCLYSTVEITIGIICACMPTLRMILVRIWPRVFDGSLVRRATGAYAAYGKSPKSYNDDSKHNTQSDGSKSKKSGIGSRGSLYWKQQLSPLWRNNEAKEDKVFVDGIQFSALSRSELEQGDDRRLVTPENWHTAITISAGRTRGGRDTPTTLASSVRSAEEAQPFPYSAPDRGRRPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4D9</accession>
    <name>A0ABR1V4D9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein disulfide-isomerase</fullName>
            <ecNumber evidence="4">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012807</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662813.1">
        <property type="nucleotide sequence ID" value="XM_066817121.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050181"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF132">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047246738" description="protein disulfide-isomerase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="354" mass="38976" checksum="35BA6F5F7BC449DE" modified="2025-10-08" version="1">MLKLGLAAWLAATGVCAWEHVSPSDLETSIKSHDAVVVASLELEWTPAVAELTAISALSVDCSQAANICQQHGVSEYPSLKLFQGGESKSTYLGPRRASAITSWIKRIQRPLVSEVSAEDLEAFKSGDETVFLAYLNADDQESRKTYEEIALQFRDEFTFGVNVGDEAARQAEGVESPGLKCHRHLDGDVVTFKGSFDADGLKAFVIEASRAWPMVYLFAATEPERAEFRRALHKIGRSYYESLTMTTVDPLDFPSLPARLGLEAKYPCGAVHQLSKDRIYHYPRDYPVTPSALQKWGLDVWQGRVNPWSPDGEAAAATKAQQGNEMPGRIRATPRVSIASFPGLNIRIGRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V689</accession>
    <name>A0ABR1V689_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663471.1">
        <property type="nucleotide sequence ID" value="XM_066817779.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050839"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="83" mass="8940" checksum="F390EBC2DC790F53" modified="2025-10-08" version="1">MPGFTLRPSAQRSSIIGIRCRRRTSRSKWRLGSRDSEEEGGAAGREGSVSKCRRGRGGGGGEENDDGQAAKTQRDELAPAAHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V731</accession>
    <name>A0ABR1V731_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COP9 signalosome complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_012873</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the COP9 signalosome (CSN) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662879.1">
        <property type="nucleotide sequence ID" value="XM_066817187.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050247"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040961">
        <property type="entry name" value="CSN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18323">
        <property type="entry name" value="CSN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="11">
        <location>
            <begin position="51"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8066126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="357" mass="39197" checksum="3FC73442C38D03E6" modified="2025-10-08" version="1">MEVAMKSWELDNDVKLVDETRDALYAYSPADQKAINEKKPWKENPHHFKHVRISAVALIKMVMHARSGGEIEVMGLMQGYVSGDTFIVTDAFGLPVEGTETRVNAQGDANEYMIEYLQLSRDQGGREENVVGWYHSHPGYGCWLSGIDVDTQALQQQFQDPFCAVVIDPDRTISAGRVEIGAFRTFPQGYKASDNAGSSSGNTKESQEHGGTSVPLAKAADFGAHANKYYSMEVSHFKSTLDTKLLELLWNKYWVQTLSQSPLLTNRDFGNKQMLDLGSKIREASQMISRATRGGPGGMFGTAITSRATDADLEKLSRDSRAVVGKEVQGLMATDVKVKVFNGLGNNNDGSTAPVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V751</accession>
    <name>A0ABR1V751_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012888</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662894.1">
        <property type="nucleotide sequence ID" value="XM_066817202.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050262"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018620">
        <property type="entry name" value="Ubiquitin3-bd_protein_But2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39613">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39613:SF1">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09792">
        <property type="entry name" value="But2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045679748" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin 3 binding protein But2 C-terminal" evidence="3">
        <location>
            <begin position="45"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin 3 binding protein But2 C-terminal" evidence="3">
        <location>
            <begin position="156"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="258" mass="27099" checksum="61C11BDE587FED78" modified="2025-10-08" version="1">MKTTIVATTFAATALAVPALDALVQCPKNTAQPDGNLPASIQDYISAKEPNKKFAGSVTAEVTPGDKCTIFNLDIPVKESQGKVCNLVFDFPEKPTSALKARAQGLVGDFGGDLVADHRRPGHGGKEGEHKPAGGEHPHHGKNLPRLSSPLASSLDYKFDGPGNFKFIGYDIGVGAVAGETTYANQPKSGPSPPNPPPKMQPGHSYVINAGDCEFPANLTSVKVSGALCSDDTTMRYDQGYLGSCPIGFYVVLTDAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7N0</accession>
    <name>A0ABR1V7N0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2og-Fe oxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662741.1">
        <property type="nucleotide sequence ID" value="XM_066817049.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050109"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="181"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="325" mass="35833" checksum="5379D2A2686FE32C" modified="2025-10-08" version="1">MPEPSPCFQVPTVDIGPYLRDPLSDAAAGAVDAVRKACISSGFFRVANHGISKGLQDSMQRAAEALFALPLEEKTKLIHPTLTNRGYELIGSQVLQPDALPDLKEGFCVGQHMDLDDERVRSHPQLMGPNIFPPNLEDHVLKIPAQQYYTEMFSLACRIMEMLARGLPYGDDIFVPFMSNDPVCILRLLHYPPQTSSDKRQLGAGAHTDFGAITLLWQDSCGGLQVQDGRTGVWHAIEPDPECLVVNIGDMLSVWTNVYQSTVHRVINRGGQGRYSMAFFVDGNTDVQLAPLDGSVPATGKIMTTEEHMEHRIGKTYRKVAAQAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7Y3</accession>
    <name>A0ABR1V7Y3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydantoinase/oxoprolinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014054</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664060.1">
        <property type="nucleotide sequence ID" value="XM_066818368.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051428"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.390.10">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1610.10">
        <property type="entry name" value="CV3147-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048350">
        <property type="entry name" value="S-Me-THD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024071">
        <property type="entry name" value="S-Me-THD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010318">
        <property type="entry name" value="S-Me-THD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027479">
        <property type="entry name" value="S-Me-THD_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF10">
        <property type="entry name" value="HYDANTOINASE_OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20906">
        <property type="entry name" value="S-Me-THD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06032">
        <property type="entry name" value="S-Me-THD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160991">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="2">
        <location>
            <begin position="247"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD N-terminal" evidence="3">
        <location>
            <begin position="636"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD-like C-terminal" evidence="4">
        <location>
            <begin position="799"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8067307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1034" mass="110521" checksum="44CE94949BDB47D9" modified="2025-10-08" version="1">MCSNLQPHTAPILSPKGPDDYRLDSDSCLVCDESPKRLYLRTYFRPSLDNEKMGSQSVEMPKTVRIGVDVGGKHQYGCRSDQPNPAVRARPRRPSPPQNPTTPDVTLGIEAAVRTVLAQSQLAASAIASVTVGTTHFINALPARDPAFLGVPPALTRIIRGYVGYCDGGLHIDGSEEAPVVEAQVVERCREIRALGLTAVVVVGAFSPIDEVFHQEDRVREIVLREMPPGTDVVVSHEVANIGLLERENASILNAAILQYARRTVRGFRRAMKALDLHCPLFLTQNDGTLLDAAAAAKIPIRTFNSGATNSMRGAAYLAGHDTQHSSAIVADIGGTTTDVGVLLSSGLPRQASAYVTVAGVRVNYSMPHLHSVGLGGGSIVRHTEDGEVTVGPGSVGHYLTQKALAFGGDVVTASDIAVAAGRAKMGTCAVKLDRDLVTNAEHQIKKLLEGVVDLIKTSPEPLPVLLVGGGAVLSPSTLEGASELRLPPFHDVANAVGAAISNVGGTVDVIQSVEGQLIREAVERAKAMAIRRAIDAGAERDSVRIAEEESYPVTYVANKLRTVVKAIGKLDINLKSGPLPEEDFEDEAEEEGSEVAKDLSMVVTEEPEPVDPSTYRPTVIRNESTGILEWHISETDINYLADGCYILGCAGGGSPAASRIQLRDMLRAGHTMRVIDASSLDPKAVVYWGGHMGSPATSNERLQSIETVYAFRALMEYRREPSFDAVISLEIGGANGLEPFLVGSSRFFDCPIIDGDFMGRAYPTYWQTTLAVHAPNELVPCAIDSGDGKTILMVRAPDDEIVDRALRASCSEMGSRVGMASCPTTAEKVDKFAVLRTVSLAWRIGRCIARAEANNTLSTVAESIVQEAGGAKSAKILFRGKIVAVERRLFKGHSHGSITIAGLSTSEEENSGTGQQGIMPAVKTGGTLMIPFKNENLFAEHTAEDGTTKTVIASVPDLICVLDTSSGRNLGVPEFKYGFRVTVLGITCSPRWTETPAGLKIGGPRAFGYDMDYHPIGDYVEPKSVIEEFAPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8E4</accession>
    <name>A0ABR1V8E4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA polymerase</fullName>
            <ecNumber evidence="9">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_013081</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663087.1">
        <property type="nucleotide sequence ID" value="XM_066817395.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050455"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.730">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="12">
        <location>
            <begin position="224"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="11">
        <location>
            <begin position="520"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8066334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1058" mass="119528" checksum="0AAB7885ECC232CD" modified="2025-10-08" version="1">MATANLPQKRGIGEASRARRNPPLTPSKKRRLEPLTSSPASRLNSSQQGPGGKLSSTQPKSAFESEVLEKLSQDISDLKQSNSEKDQCRARPALGDFDPKRDNLIFQQIDAEEGTLHGGRVTVKLFGVTETGHSVMLHVTDFRHYLYVAAPVSFRPEDCQAFKVFLETQVAQHQPTIYSCQLVLRENIYGFQGNTQSPYIKITRGDANWKGMWKGASDGIMTFDNLQYVLRFMVDCKMPGMSWIECPAKKYTLIPPRDRQSSAQIEAEISYTNMIAHDAKGEWSKMAPLRILSFDIECAGRKGIFPEANQDPVIQIANVVTRYGENKPFIRNVFCLDETSSIVATEILSFEKEQDMLMSWKKFLDEVDPDLITGYNISNFDFPYLLDRARHLKLNGFEYWTRLPSVKSVAKETNFSSKQMGNRDTKTTNTNGRLQLDLLQLMQRDHQLRSYTLNSVCSHFLGEQKEDVHHTMITELFNGTPESRRRLALYCLKDAYLPQRLMDKLSCLANYTEMARVTGVPFNFLLSRGQQVKFMSQLFRKALEQKLVIPNLKSEASDEQYEGATVIEPTRGYYDVPIATLDFASLYPSIIQAHNLCYTTLLNKNAVEKFGLKKDEDYIVTPHGDLFATASRRKSLLAQIFEELLGARKQAKRELAVETDPFKKAVLNGRQLALKISANSVYGLTGATTGKLPCLPIASSTTSYGRQMIEKTKEEVEKKYCIANGYSHDAQVIYGDTDSVMVKFGMKDLAEAMKLGEEAANYVSAKFIKPIKLEFEKVYYPYLLINKKRYAGLYWTKPEKFDKMDTKGIETVRRDNCLLVQTVIEKVLRMMLIDEDVNGAQEYVKETISDLLQNKVDMSKLVITKALTKENYDGKQAHVELAERMKKRDAGSAPGLGDRVAYVMIKGASGSKNWERSEDPIFVLENNVPIDTRYYLDNQLAKPLTRIFEPILGETKAKSLLTGDHTRAISVAAPTVGGLMKFAKKTMTCMACKKPLVGKEESAGAVCKSDTLPSCMHNEVICSSKDCPIFYMRMKAKKDLEDAGKELKRFDFDQAAIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9M1</accession>
    <name>A0ABR1V9M1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013501</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663507.1">
        <property type="nucleotide sequence ID" value="XM_066817815.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050875"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="47203" checksum="4058D2C9079B365B" modified="2025-10-08" version="1" fragment="single">TNPSQAPANPQTPRPRRPPPPGPKTVKTGLAKPWLYFRELSAQYGDIVSVPGLSSSPTTIVLGSARTAWDLLERRGAVYSSRPRFVVGGELLSGGLRGLMAPYGDFWRHWRRLLHSGFMQRRSASYRPIQRLESAVLARDLLRDPRGVPGASGEHPGQIRRREVPSAQVYPDCFCLLEGRSAQAAPKGHTAVYGSLERYQGQGCERRRNALFHDAPSRGTGGFRHVGFGARIQRGLAIRCGHRNGKLAPNPKSTAGTLASFFLACVKFGHNFIPRAQEELDRVIGRDRLPTFEDMEDLEYIRAVASETLRWRPGAVLGGTPHASTADDVYNGMFIPKGSTIIAPLWTIHLNEKDFPEPHEFKPERFLEERDFPGTLGHTAFGWGRRFCPGMHLGAASINLNIARILWAFNVSPAKDETGQDIDVDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAM0</accession>
    <name>A0ABR1VAM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014042</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664048.1">
        <property type="nucleotide sequence ID" value="XM_066818356.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051416"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF78">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8067295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="45747" checksum="5607B02540EDE270" modified="2025-10-08" version="1">MQYHLHIPKLQEEYGDFIRTGPREITVIRASAVDLIYGPSSKCTKATWYDQNSGDPNKVGIENVRDKEKHRIRRRAWDRGMGLRALSTYESRIKNKVDSLMLRFGAGEPVDVTQDVIFYAWDVMGDIAFSVDFQMLHTGVEHPAVDGLHWAMATAGLVTNFPWLMNMLRVIPGATGRFQKFADWCYEQVDLKRDALAREKAEGRAQEPRDVMSWIIKAQQDGDRSAPPTESAIREDARTLISAGSDTVAIAFTNFQKIPYIDHLIHETLRLRPPAPMGFLRETPPAGLQVDDVFIPGGVNVNVPTWTIQRDERYFSRALDFVPERWEAPSAESATAYLAFQRGPFQCSGKAVAMMQMRMLVSCVALRYNLAFAPGEDGEEFWKGAKETMTLWLPPLRMVFEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI34</accession>
    <name>A0ABR1VI34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ferric reductase transmembrane component 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_011104</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664709.1">
        <property type="nucleotide sequence ID" value="XM_066815419.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048479"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF23">
        <property type="entry name" value="FERRIC-CHELATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00410">
        <property type="entry name" value="PHEHYDRXLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="10">
        <location>
            <begin position="175"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric reductase NAD binding" evidence="11">
        <location>
            <begin position="440"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="610"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="697"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8070901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="825" mass="93562" checksum="57C7BDE32BA69A09" modified="2025-10-08" version="1">MASEIQGVMAGASRTIGQLAKRIHIPLTATSPPGLVEALTVDPWDRAGKYGLGWTYFCLALMGSVLFVRIWHWWQDKIRQAIYKQDVERHYRDLYSLDPEQAMTAMQTEQPGRHFFPETNHEEKKDFKPRSDFSSITPVLDALALFRWVFYRPIPDLPLYWQSIQFGSPPVAIRAGMIAVAMTPWIIASSMKTNVLTYITGIGPERLNVFHRWAGYLCLFMSLVHTVPFYIQPVWDDGGMQTFSRLFPEGSGVIYGTGISCLVPLVWLCVASLPFIRRVAFEAFVVLHVPVGMVYVGLLFWHTKNFLASWSYLYSTIAIWAFCYALRLFKLNWTKPWRLAFMVGDEAAITLMTENAIKVTIPTQMRWSPGQYVYLRMPGISEDFPSEYGEQYRDCVLVFKPYGGFTRRVLETAIQKGPFHTYRAYLDGPYGGMRRELSAFDTCILIAGGSGITSLMSQLLNLIKRMRDGKAITKKVVVIWALKRLEAMDWFREELRICRESAPPESVTCKFFVTSAVRQRVGAGLGAGVGERAQRPLSTMFHDRLDGFVAGVASKRASTYIRDEAQGNVDYERELRAEDEDRITALPQQRYLQPHHEDSLRRLEGREDEHMEIQEDHGDAPPPPPPPSGFEYPEDKPKQGFQFPPLHLRPEKQPHFNYAPPSPRRFDGSNTQTPGQEHRSAEPSQDVPRPPEFAHLRTTNLPGQGQGQPRPTSTFGPPSGFDFGFPETPTEFQKSLMRFAFPVPHQIDGGWSVEYGRPDLGYMLKEWATGGTDGRGILGRRTAVFVCGPASMRVGVANTVARLQAEIWGDDMLEEIFLHTENYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI66</accession>
    <name>A0ABR1VI66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011125</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664730.1">
        <property type="nucleotide sequence ID" value="XM_066815440.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048500"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045909298" description="Cytochrome P450 monooxygenase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="214"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8070922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="65503" checksum="5FE5D2B32B7BCDF1" modified="2025-10-08" version="1">MIGLILIFLSLALLYSLYGWALPKPIPGIPYEATATKSLWGNMSEIMAFKKRHGEVRPWFARQAVRHRAPLTQAWLTPFSRPVLILSDYREAQDVFLRRGRDFFRGPRSCDAFHGSIPEHHIAMMSADPRFKRNKELVRDLMTPGFLHDVSAPQIHAKSMMLVDLWTQKSRLAQGRPFDALADLFDVAMDMINAAAFALDDDMSTTKAQLDFLSSSNNSSPASSGDDNDNDKNAWSPVTSAGPHGGVQFPRPPELPDIAACHALAGHVGVLFNSLAPRLEDRWRMLTSARLRASVKRKDRMIARAIERSLERMGRGGGGGKEAVPTSALDHLLTREKAAAMKTGREPDFHSRKIYDELLGYIVAGHETSATGLSWMIKLLATHQDVQARLRGTLRATYAAATTESRQPTAQEVALASAPYLDAVIEESLRYAPPIPLLIRTARADTTLLGHAVPRGTDVFMPALGPGYTAPAAAAVAESARSESSRAKGWGGRWDEGDMHLFRPERWLKTDEEDGSKESFDPQAGPMITFGLGLRSCFGKRLAYLEMRMMLALLVWNFEFKKLEGPLASNEANESITTYPKSCYVALEKLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIJ1</accession>
    <name>A0ABR1VIJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DFP-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011228</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664833.1">
        <property type="nucleotide sequence ID" value="XM_066815543.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048603"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/pantothenate metabolism flavoprotein C-terminal" evidence="3">
        <location>
            <begin position="99"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="390"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="394"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8071025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="448" mass="50095" checksum="41A26B98709285F2" modified="2025-10-08" version="1">MTPQTTQFSETISPLHTEDKSSALSLSFNIGPARPPSPSSSISSVLTEDTMASSATADTAASSQQGVENAYFSSNPPPKALTSHVEQARSFIDHHASLKRRVVLVTSGGTTVPLEKQTVRFIDNFSAGTRGATSAEYFLEAGYAVIFLHRQFSLLPYSRHYSHSTDCFLDFLHEADDGSVVANPTHQEKMLSVLRKYNDAKRERKLLMIPFTTITDYLYELRAVAQLMRPLGPNGLLYLAAAVSDFFVPSDRMSEHKIQSTNATAGFKKEQGSTTVADKPRRSTDEPEETFDNFDSSPAVPRSKRLIIDLDPVPKFLKMLVDGWAPEGMIVSFKLETDPEILVHKAKYSLDRYQHHLVIGNLLTTRKWEVVFVAPNQPDQWIRVPGHRRRKTFGSKDKEDQNWEAQDKPLDPTMLPDGDPEMEIEGLIIPAVQNLHQKHIDSVKAKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ60</accession>
    <name>A0ABR1VJ60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665084.1">
        <property type="nucleotide sequence ID" value="XM_066815794.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048854"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="565" mass="60846" checksum="145CEA9E5B74C1A4" modified="2025-10-08" version="1">MAQNSFASPTGLGMPSGGLASRRGGQSIKPLSFDAIKAQPNSGDNGAPTPRTSRSHLLAGLRTAPKSATTGNFPASPTTAAPTSQQMYGNNNGMSSNMYAAPAGQQQQPQQQQPQRQQQQQSYNQMMGGGQQQYANGQHYTAEQILPPPEIHLDEQEEGMDPLLYAQMMQANLYLAQQQQRLQQQLMQVQAAAQQFQGLSLNGQATVQQQIAISTLYQQQQQQLRNLQQQMASMPSIQQMQQPQQNIYTYYDPSTGQTYYVDQSQAQNGFNQANNNVYMEQPSTPQNFSFQQNNTPRVQVSPPADNEKPFFRSNSPPKKMELTGEPEPLPPPSANAFRRGHKKSGSQAGSNGALSLTTDNGPRTAGPKTASFPISPMPNAYGPGQARAGEHPLRQPRGPPAIDELRAKPTSRHEGSKNFAARTRRSALNNLVRAGFERRKGTGSSSGSMSPVSETAEEVGTPLTDNESDSGRSGSGSLSGDAEPSLASSRTSASGSWGLLVPIARKTRKSVDSLSSQCDSDSGSFASVFKKGSQRDNKPQSVDGQRKAPRLVLTSAEKRKGGMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJM5</accession>
    <name>A0ABR1VJM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltetrahydropteroyltriglutamate-homocysteine s-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665254.1">
        <property type="nucleotide sequence ID" value="XM_066815964.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049024"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844:SF2">
        <property type="entry name" value="SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE C-terminal/archaeal" evidence="1">
        <location>
            <begin position="182"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="402" mass="45337" checksum="B1591C742D35BA02" modified="2025-10-08" version="1">MATNKQRPPFRAEHLGSLLRPKEITDKRIALDNAKALEIVQDKELSTLEDNAINEIVKVQLDLGFHAIGDGEYRRHQFWGTFFPNLEGFEEIPNPDWDMFRLYVPDTAAFTETGHKPGETIVCTGKIKHVGSSYMKDWEYLKKLVPADRVKELKITLAAPEWYHLRYKKGKAYPQEVYANDAEYFADIAAAYRAELQTLYDAGCRNVTIDDPNLAYFCSEKMLAGFKEDGEDAEALLDSYVTLYNDCLSGRPADMHVGIHLCRGNFAYSKHFSEGGYDRIATKLFNGISADTYFLEYDTERAGTFEPLKHLPKHKNVVLGVITSKFPELEDVGKLKERVYEAADVVASGAGQTREEALQRLGVSPQCGFASHHLGNSVTREDMIAKLKLVRELADAIWPGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VL05</accession>
    <name>A0ABR1VL05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Terpene cyclase/mutase family member</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010827</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the terpene cyclase/mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664432.1">
        <property type="nucleotide sequence ID" value="XM_066815142.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048202"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006400">
        <property type="entry name" value="Hopene-cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032697">
        <property type="entry name" value="SQ_cyclase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018333">
        <property type="entry name" value="Squalene_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01507">
        <property type="entry name" value="hopene_cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01787">
        <property type="entry name" value="squalene_cyclas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764">
        <property type="entry name" value="TERPENE CYCLASE/MUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764:SF82">
        <property type="entry name" value="TERPENE CYCLASE_MUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13249">
        <property type="entry name" value="SQHop_cyclase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01016">
        <property type="entry name" value="Prenyltransferase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Squalene cyclase N-terminal" evidence="6">
        <location>
            <begin position="30"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Squalene cyclase C-terminal" evidence="5">
        <location>
            <begin position="336"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8070624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="755" mass="83927" checksum="41162B22F0973597" modified="2025-10-08" version="1">MDSQTKVISPVARDAGHDLYALAQNAHQLAVQHAWELRRPDGHWNGELLSNATITAEQVFFHQSLRPATPIPDGDAYRHYLLSNQQKDGAWSIAPDHPGDVSTSAEAYLALKILGVPPHHDAMRRGRAFIRRCGGVAKVRIFTRIFFAQFGLFPWDAVPQLPAEFILCPSWAPINVYRLSSWARSTLVPLLIIRHHQKIYPLPDCAPDPQSTYLDELWIDPGNKHVPYGPSLLRPWESDLWSLMFGGIDTALYWLGGLKRFWPVRRYARRKCVEWILERQEKQGDWAGIIPPMHAGVQALLLEGYKLEDPHIQSAIAAIERFTWQDEGGKRLQSCVSPVWDTVLMTRALCDGPTISSGSNKGEFEETEERGPQPDDERLRQTIRWIKTHQLLGPEGDWRIYSPALAPGGFSFEYSNTWYPDVDDTAAAILALVGQDPAGALDSATVTSAAAWICGMQNRDGGWAAFDLDNDRLWLNSIPFSDMDALCDPSSADVTGRILEAFGLMQRLAAQGEFLNARTLELIGRACPRGVAYLLQQQEQSGPWYGRWGSNYIYGTSNVLCGLAYFSESDEKVADAVRAAAEWLESVQNADGGWGEGLQSYRYPERAGRGGPSTPSQTAWALMGLLAVCNGKTSSAIESGIKHMVETQVYSGGGGEHSPGKIAATWTERQYTGTGFPNFFYIGYSLYRHYFPIMALGRYLSAFSKVQSDEKIINDSDAGSRTISSLEEEMLESPMDSGYSDTSASCELKVDLKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VNH3</accession>
    <name>A0ABR1VNH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665211.1">
        <property type="nucleotide sequence ID" value="XM_066815921.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048981"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="159" mass="16355" checksum="70C9406EA6E7951D" modified="2025-10-08" version="1">MLTTEASLSCAINAYRLHIMSSPLVTSLRKSQQSTPIPARDAGPVAVAKVARRAVGAEVALEPGATVPHAGRDGLVVLLGGPLHGADEVERLPRGLDLGAVAGVPEAPVADGDAHVAEVHVLVAEGPDSAFVAVAPIFRHTVLAEYSLTSWRSFKEGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VSY4</accession>
    <name>A0ABR1VSY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665326.1">
        <property type="nucleotide sequence ID" value="XM_066813364.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046424"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="95" mass="9829" checksum="F153E01388F64BAC" modified="2025-10-08" version="1">MPAITIVVTEPTPTPTLTPTPPASLPIDLGNGHITTEDFFAALGLSHSWVDAGKAMISGGKAEEKGGDGGTEPSAQDGRAPFDSDERRKCRVEPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT72</accession>
    <name>A0ABR1VT72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665396.1">
        <property type="nucleotide sequence ID" value="XM_066813434.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046494"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="425" mass="47685" checksum="BFB992DA05587F95" modified="2025-10-08" version="1">MPRSYLNGTKLGPVGVFKLLAAAYGLLLAAELIYIVVQCIMVYQLSQIESAGGSCAVALKWTNDFRELPRALQLAQSDAGVVSDALARVRKKRKDPNATQQLVDGYSKALIPSIISWAEMSDEIVDAARQIGAVISLLQGHMEEVSGFHPAFRYALGHRGDAGYLLLQGRIQSSVDAATEVLDRVGLITGQARGNFTTLLMKLGYLMEVIEKDHQTIQLDQRYRLKGGHMYLCNLSNMCGLIGSNWISEATLQELQVELFETKQTLDHTFKLARDAYKGLAVIMFQIDITRKGLVEAKQANTWRDGSTAERNFLINSKRWTLELRVRIEQLSDLQHQYYSQTQNETAPRKYIDCYSRKIKGMRCFLIRDVNAPHSKQDWTMAALAYQTIQSPAESPILQDGQQHASVSFTTRSAHYSSPIYPKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU60</accession>
    <name>A0ABR1VU60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665687.1">
        <property type="nucleotide sequence ID" value="XM_066813725.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046785"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF2">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="587"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="620"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="3">
        <location>
            <begin position="118"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="662"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="693" mass="78644" checksum="519BDD3AD09AC57A" modified="2025-10-08" version="1">MSLPFRDINVQVAPDSYTFTSPSSPNAPALVIDRPTGDLRLSEGSSYPNKRITRQTSIAGILGMIRLRLDKYVIIITKAQPMGRLKGHMVYKVISTDFLPMRERQIRDPDEDQFLSLLKTFVMTGPMYFSYSLDLTNSFQRQASIDNSKPLWMRADDRFFWNKFVQTDLMDFRTRGSRSQHGAQPAADPFILPIMWGTLEIRPTTLKGQPLTISLVTRKSRYRAGTRYFTRGLDSEGHAANYNETEQIVILNDTGSGMGGFAGSTDMQSGKLGGSEGKEMQILSYVQTRGSIPTYWAEVNALKYTPKLQVKSCEMALPAAKKHFDEQIRIYGDNYLVNLVNQKGREKRMKDAYEEMVSTLVSSPKEGTKADSRTDEKFHVVEPSSSRQEFDRLHYVYFDYHHETRGMQMQRAMLLVDQLKDALMVQQYFRGVDMPANGGLETRNFQTSIVRTNCMDSLDRTNVVQSMLARWTLDRMFIDLGLLQRGEDFATADTDFYFLFRNIWADNADTVSRAYAGTGAMKTDITRMGTRTTAGKLADGNIAITRFYLNNFRDGPRQDAFDLFLGAYEPSEGNIGSSLIFADRRPVLIQSIPYVFAFSVLFIFLALVTRRPADASVITMRLFILFWTVVAAWCGQFILSNGMLYVNWPKLNPRPWAVEGLPRHDQQDQEGQADRAAGGEARTGFEHCEVPQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU63</accession>
    <name>A0ABR1VU63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665731.1">
        <property type="nucleotide sequence ID" value="XM_066813769.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046829"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="222" mass="25139" checksum="A7154ED589A3B866" modified="2025-10-08" version="1">MARKQQRPKDMDPAINFPQYGMPPFPFNPYPAFGGGMPYVNPNGAPFVVHPFASSVDLPRPYAVAKKDHRDGIAGGPGPWDAGKTPTDIDSMLSAAERVCTAARNIYEQSKESVNIYQRLKNFDDDVEKVKDYIGDNLLQQIWTKKMEKLQRDKTKGPPRMQLASQQEYLAESFDELDAAARDLLDKLPRSHHQYDNRKTALDQLRQAGDRVRGVLRQGQHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUP1</accession>
    <name>A0ABR1VUP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009555</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665832.1">
        <property type="nucleotide sequence ID" value="XM_066813870.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046930"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07105">
        <property type="entry name" value="ALDH_SaliADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF6">
        <property type="entry name" value="CYTOPLASMIC ALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="19"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="475" mass="50812" checksum="4AFA5CE6570FD471" modified="2025-10-08" version="1">MVDYVVPFIIDGKEVRPSATFDVVSPSTGKLVHKCGVATKEHAKAAVDAASRALPAWRDVTPSKRRDYLLKTAEIMERRRDELAGYLIDATGCTQDWADLNIDGSVDQIKDIAGRISSQCGAVPSLADPSLGAMVLKEPFGVVFAIAPWNAPYILGVRSVCQPIAAGNTTVFKGSELSPAVFWAITSCFQEAGVPDGVINFLSTNPANAAEVTESLIADPAVRKVNFTGSTAVGRIIGRLCGQHLKPVVLELGGKAPAIVWEDANLDIAAEQCALGAFLFSGQICMSTERILVHKKVSAEFQKKFAATIDAIFPAGADAPVLINTNAVDKVKKLLDNAVSKGASVLAGDFNATETSKTRLRPVVITKVTPDMDIYQTESFGPSVSLIEIETEEEALRIANDTEYGLSSSVFTEDLRTGLRFAKGIESGAVHINNMTVHDEANLPHGGGKNSGYGRFNTTLGLDEWTKAKTITWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV09</accession>
    <name>A0ABR1VV09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666025.1">
        <property type="nucleotide sequence ID" value="XM_066814063.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047123"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336:SF3">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="2">
        <location>
            <begin position="14"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="256" mass="28238" checksum="4841412C1D057415" modified="2025-10-08" version="1">MGVFYEAIPDSMIPWLRAQKMFWIATAPLSARGHVNVSPKGGDCFGIPDSRSFWYHDLTGSGNETISHLYENGRVTVMFHAFEGPPRIVRLYGTGSVLESGTAAYDAFVADNKIETFFGSRSIIRVDVHQASSSCGFSVPFYEFKEFRPTLHEHFERKAVKFDAGNEKESMPRYWALKNAWSVDNIPGMKAGLKAGSEESIAPIKKMVGISPPKGYQGAVGQGFTLSQLIFAMLFSASFSVVLVLFADSLSPRSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWH2</accession>
    <name>A0ABR1VWH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666550.1">
        <property type="nucleotide sequence ID" value="XM_066814588.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047648"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="122" mass="12716" checksum="E122B54D8EDF7DC1" modified="2025-10-08" version="1">MANLGNVTNLGMGVIPANFDGGLHNAPANQWVMFTSGLAHVTVPGDDSDGAYILGGEFGLIFAADTADVSEKGHYTRYPGIVETVALQIPTLDGEIPPHQVVRSRPCHANDTVGLRAFAGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWK2</accession>
    <name>A0ABR1VWK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666580.1">
        <property type="nucleotide sequence ID" value="XM_066814618.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047678"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF213">
        <property type="entry name" value="DEPENDENT OXIDOREDUCTASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="74"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="541" mass="58302" checksum="CF1E240CF0A06905" modified="2025-10-08" version="1">MGTIISVVQDHARSLFSAITLLQDQWKDFQAAVARASLSPGLPVSNPSTPYWTQDPPYPELVKHQSAELPSQADVVIIGSGISGAAVAHSLLVLGAKNSSAGHRFDIIVVLEARDICSGATARNGGHIKASAYDVYPRFAKTMPQDRAVALTRFQLHHLDVLVDLCKARGIDAAEARQVETVDLFLDKTSFEKAVRNVDETKANLPEDETRTWQRKEAQEKFGTGETVAGAISYKAGAIWAYRFVTTLWHQLLAEFPDALSIETHTPVEAILADDPRAPKGYPYAIQTPRGTIFARNIVHATNGHASHLVPGLRRKITPAQAHMSAQKPGRLFSQDHGAHRSWGVVYENGFDYITQRQPEPDAGSARQSQGDLLLGGGFVRSSKQGIDMIGLSDDGASLDGLTLAHIAGIFPAVFSPNWGGGAEIKQAWSGTLGFTGDLIPLVGKLGKSLTGRTPPNAVVSGSDEKPSGEWIAAGFSGEGMVWAWLTGRALGIIMSAREDDDMAGGPGWPAGRLLDWFPREILVSEQRLRSADLINLTNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWP6</accession>
    <name>A0ABR1VWP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666594.1">
        <property type="nucleotide sequence ID" value="XM_066814632.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047692"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="200" mass="23192" checksum="FE2546A902A0C0C6" modified="2025-10-08" version="1">MFSNGEDEGKLRGYKPPYGGFGAEEELPNYCSYCSKGEKFDPKDEKFDPKDATDSPGWSKASELSFEALREFFVPLLFHWSQRGLLEHNDWKVLFRFHEIAVDRLDKVRLEAIKELDYNAEANTRHEKLKVYREFLEFILLELLRIMDVLHNPQDSRIKKPHYSTLKWMEDIPGSGNILKQIDGMGSAGPRHLATISEIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWW9</accession>
    <name>A0ABR1VWW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665751.1">
        <property type="nucleotide sequence ID" value="XM_066813789.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046849"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024526">
        <property type="entry name" value="DUF3807"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40642">
        <property type="entry name" value="YALI0F31295P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40642:SF1">
        <property type="entry name" value="YALI0F31295P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12720">
        <property type="entry name" value="DUF3807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="206" mass="23027" checksum="DC5851C00D1FB650" modified="2025-10-08" version="1">MAAAINNPPNVSQHLSANFIENSTATKDDTYDANDEYFVGEEEDDLGYYSDGVKRTLTDEQIAIFRHSELETLRREKANGTKSSNSQTGQTKNRPPNTDSTKQDDGQQASGSEDGELESDTPQPISAAVKRKKARKNRKKARNAAHNPQQHEPGWFKKNVKPDLRKRTWDKVETGMDSLDYEDAPQAESGNGVGPPTQRRKISYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWY5</accession>
    <name>A0ABR1VWY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010439</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666716.1">
        <property type="nucleotide sequence ID" value="XM_066814754.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047814"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF54">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="61"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="517" mass="56710" checksum="A3EE1C65D011CE75" modified="2025-10-08" version="1">MANTSHDNTETYPDDKADVKTVEHAAGINPYSSLSAADADFMRSYEGKRGKKVVRKIDLRLIPIMALLYLCSHIDRGNIGNAKIEGMDKDLGLTGNQYNIASTIFFIPYIIFEIPSNIVLKKLRPSIWLSALVISWGVVMTLMGVVQNFQGMVACRVFLGLCEAGFFPGAVFIVSSWYPRYELQQRLALFYTASAFSGALSGLLAFALARLDGTRGVRGWRWIFLLEGAATVGLGLCMPFLLVDTPERAGWLTGGEKRFVDLRLRLSGVRTASHATEQEVDKFSWRLLGRTMVDWKIGCGIVLAWANSVPNAAFKFTMPQIIAQLGFTASKAQLLTIPPYFCGGVSAWLVGRYSDRLAWRFPFIVGPLSVLMAALAVLFAFSPDVKNKVAVMYFGVVLAQIGIYPLLPGISAWVGNNLAPSSKRSIGLAWLLAAGNLGSLVGTNIFLDREGPRYPTGYGTALGIICLAMLMAGILEFSLWKLNKAKAVQSEIEIRSKYTQGQLDGMGEKSPLYQYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX12</accession>
    <name>A0ABR1VX12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate esterase family 3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010469</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666746.1">
        <property type="nucleotide sequence ID" value="XM_066814784.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047844"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF31">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="3">
        <location>
            <begin position="174"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="441" mass="48111" checksum="27AF544932CBF626" modified="2025-10-08" version="1">MAAAPQGVESTTTTTSVTPTEAEVHEKKVKPPKRDCRTMWSARVAFLRTKRAIAGITIFVVIAILLISLGGTHVLDGTYRGKIPEEGESKTCKLYHDLHTYLLLHQCPVAMLLPSSVPVPAGVVVANVPAIYHAANCPKKQLGRSALVSCLPQSNARRQFPGSIKNGTALRIMALGASTVKGQNSPGDNGFRKQLRDELTELGVPVNMVGSVKAGEMLDNECEAQGGARVSEVFKRAKRVVPEMQPNVFLINAGVNNALQLFELETAGRDMEDMVNYLLDTSPRSFVVISTLLTNTLKDCEQYMLQVNQQLWDVFAKLEREGKWVLMADMHYSGKDPDAILPEDITPDGTHPTAEAYSKMGHIFVKAIQRADKLGYIQVPAPNGIPDDGEAEALAAQNAPAQPLAKRIAAASDNVVQYLTAEEGRKRFMLQRRAWCGVPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXK8</accession>
    <name>A0ABR1VXK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666517.1">
        <property type="nucleotide sequence ID" value="XM_066814555.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047615"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045790628" evidence="2">
        <location>
            <begin position="19"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="143" mass="14805" checksum="453B133520974328" modified="2025-10-08" version="1">MQLTHLLAIASLAATAIAHPVADPPNPDVPNPDVPNPDVPSPDVPAPDAPSPAPEPPAEPPVGRDILERADEKKPPKTTSTSAMNPGSTTTVNICITINVNVNSSGKTPKCPGTAKYPCGWANSAKTQYKCCVRNTPSSVLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY47</accession>
    <name>A0ABR1VY47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009939</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666216.1">
        <property type="nucleotide sequence ID" value="XM_066814254.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047314"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="32"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="336"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="351" mass="39536" checksum="63E2EECADBE75976" modified="2025-10-08" version="1">MTAFRPVQTATQGTIIAMAILFSVLPTGAVGLRLWARRLSGQRLQWSDGLIVCENAVLVVFWSLIIFTHVLVVILAGGLGRNDNNTTKAMSETDIERCEVRDEPPYPLLEYRDKMSHYHPMLTSDVRQGETALQAMFGLAVYLVKLSALALFHELFYNKGSKAVRTVLNVVTYLTVVCTTVAITGTLYISFPARPWCDPTTKITHDQMYKNMINGMFNFTATVVLDFAIFFIPIWQLFPLRLQRRKKRHIMIAFGLGFLACVVALVRTVVWYDTKAKMRILVGYFLLGLEPSVGTIAICIPLFRPIFQRRTRATDGVRMQRLPSRVKSGDSEEGTKSPTTIVASPKTSYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYP4</accession>
    <name>A0ABR1VYP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009636</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665913.1">
        <property type="nucleotide sequence ID" value="XM_066813951.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047011"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046616770" evidence="8">
        <location>
            <begin position="19"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="9">
        <location>
            <begin position="73"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8074973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="436" mass="47752" checksum="46C7793F4FE5AC41" modified="2025-10-08" version="1">MKLSKVLGTGGFMPLVSACLLPGEETGDGRHHLYRRQENGDTGFPIGSGDRFEGGAKFPRGLGTQEPGTKLDSLLSVEEIESAMRGLVSEYDIETFTMPYTTFENRTMLGGKVGGSGNCSEAYHVYFNGAIHARERGSPDNLLYFISDLLYANKTRTGLTYGGRSYSASDVSRALAAGIVFVPLSNPDGVAYDQAQGNCWRKNRNPASATPGNDRSVGIDLNRNFDFLWDFPTKFEPTVAPNVAAFSEPETRNIKWVMDSFPSIRWYHDLHSFAGVVLYSWGSDENQAREPGMNFLNSTCDAVRGLMPDDPSGGIVYGEYTPSKDWSENVYAAMRTGNAMDAATGRHYEVQQAAYLYPTSGASDDYSYSRHFADPGLNLIHGFTVEFGFGNENASCPFYPTAEQYHLNMLETGAGYMEFLMASTEIGLGDEVACSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYY0</accession>
    <name>A0ABR1VYY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666486.1">
        <property type="nucleotide sequence ID" value="XM_066814524.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047584"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="62" mass="6862" checksum="CE6228D5398B9308" modified="2025-10-08" version="1">MAIDRVPYVLEDAVFVTGGGPICVTVIYVHDGRRINTRQRDSDPIPWHDDRRSGMPHGDGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZA0</accession>
    <name>A0ABR1VZA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alpha-galactosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009846</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-galactosyl-(1-&gt;3)-1D-myo-inositol + sucrose = raffinose + myo-inositol</text>
            <dbReference type="Rhea" id="RHEA:20161"/>
            <dbReference type="ChEBI" id="CHEBI:16634"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:17505"/>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
            <dbReference type="EC" id="2.4.1.82"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolases 36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666123.1">
        <property type="nucleotide sequence ID" value="XM_066814161.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047221"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008811">
        <property type="entry name" value="Glycosyl_hydrolases_36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268:SF32">
        <property type="entry name" value="GALACTINOL--SUCROSE GALACTOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05691">
        <property type="entry name" value="Raffinose_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="902" mass="100297" checksum="EECD86427730FB6C" modified="2025-10-08" version="1">MSDEPYDFATEFQAVFIPKQKPPPKPSATDMGVTQLKTGNGRLTVLLEVENNDAGDSWEVAAWHLSDGTEWREEAMTPLKEGLMSTSIQGVKTDNKRLYFTSSYSVSSNLSFTFKFRKGPSEPWRWAKDEMSIGDGMVVVNPERAHGTTNFANVVKDLNPDLTIKSHMSQSRGTELWSIEAPVGAAKGEDSTYADTRLGTPWGGFLRWFALVRIWTPWLAPRHGKTSFELDKDGIVLGFINPQGKHLVLLAVSGVDDVMTVFRHNASGQVSLHVSNSSTARHDQLCPDGYVRYATTGNPESNGLVLAAIGDHFEGALAAVVYHSRNVVLAAKKADGALDDELKALRDDVKIEWMENWYDGLGYCTWNALGQNLTDEKVYKAVDTLAENNINVTSLIIDDNWQDIDYTDPSQFQRGWNSFEADPKTFPQGLKHTISHIRSKHPNIQHIAVWHALLGYWGGITPDGPLAKTYSTVVVEREDSKRRNLPLGGPMTVIAEQDVSKFYDEFYRFLSDCGIDGVKTDAQFTIDTWVSAKHRRELTKTYLDAWMTSSLRHFSIKAISCMSQTPNILFHSQLPRNRPAMLVRNSDDFFPAIPKSHPWHIWANAHNALFTQHLNVLPDWDMFQTVHDYSGFHAAARCVSGGPIYITDAPGEHDMELIGQMTGPTIRGKTVIFRPSVVGRSIDQYNGYDDDALLKVGCYHGRAVTGTPILGVFNISSRPLTELIPLSRFSGVIPSMKYIVRAHKSERISDIVTPSSPTALLPVSLEVRGYDIFTVFPLSQFQSDTTGTIYAANLGLVGKMTGAAAIMSSDLELMHNGKVMLDTRLKALGTLGLYISTLPEMTIEGDFLATIQGEVIPPHTVSISKVDDRVLQIDVETAWNEMKLDVGWGNELEIKVFFSIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZM5</accession>
    <name>A0ABR1VZM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666243.1">
        <property type="nucleotide sequence ID" value="XM_066814281.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047341"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="38751" checksum="CD74C22BA330DF8D" modified="2025-10-08" version="1">MSDKSNKPSKSDADEVIKAMQEDIWLLVAIIEKNQMEERIKGWKEIGEKRGLSTDAAKQRYEKLKRRYHKATDGVVPPKAIVKRRYRRPKPASLDDKDDGEEPDGGDDVPSANTAHLAPPSSARAHATRAVRTPRSSRVSRATLPTSGRTQGTKRSKPVDEESDDESDDDDDEDIPAVLSASAKRQRLSARFTTKPKNNSSNEAQDDGEGLPAAQKTPAALLLPKLHMPVRRHFAIEVAQMDRDSQARSRWRQEQERQDRVMRQNLGLPTGEQDEENEAALAAQDPALHDNNDTNEAESTPKQKKKKRTPVPKLADKHRKVAERLARQRKEDEEKGQKEEDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W0P4</accession>
    <name>A0ABR1W0P4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GEgh 16 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666618.1">
        <property type="nucleotide sequence ID" value="XM_066814656.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047716"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF3">
        <property type="entry name" value="GEGH 16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045398528" description="GEgh 16 protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="34280" checksum="123CA49624A32E24" modified="2025-10-08" version="1">MSSFKVLSLAALVAVAQAHSQLLKIQGKAGSPASTGLGVDPNIARNCTTINPCQQDSTIIRDAEIKANIVNECGRNEIIGNIDIGENTENAIAAGAVTEAGPGEKLTVTLHQVNADGAGPYACDLIEQGNTGIITQNLTVQNNVPGANGFSQEKFKDFEMTVIMPQKFDCTGASTGNICTVRCRNNAQAGPFGGCFPVKQANKQAQTNNAKTIPTKSNIAAVTAQLAVDQKDFADAVAANQNAGTAEAKKADQAVKAMLAPVSSGTFPTQTVPVELGAAATAPANNNNNGNNKGNFGGNRGGNNGGFGGFPGANRNNKQQKRDILRALRMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8B5</accession>
    <name>A0ABR1W8B5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667196.1">
        <property type="nucleotide sequence ID" value="XM_066811854.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044914"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="5"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="552" mass="63028" checksum="30703802D27FBC69" modified="2025-10-08" version="1">MAALTFPLDSLPVEILCCIIRHLDPITLIAFSQTSSHYRRVISPSKLNHVERLLALELLENYGGVTTIFRSKHNIISPDWRDPACDSMRWACTSCLRLLPHTTFGNHFILGLGYRKPEPGSPAAEPVSSWEPSSRDAQYLQSLKRYKQRPGVVFEQKRLRRQYSGACTGNYWRYATARDAASCTGSADLASRLQLLMQPPPPGFEPSHVELARAWEEMAAFALEYERRNAGHKRHLRRCLECNWRRGELRPHATRYDGTLGGTPAVPVAHSRQLYYGCALYRYFPGFSAPAGNEGPPMPDAPVFVIYREDATQVPFTLHMARCPGCARWQELRAFRVGAWYPRWSIGYGTRRGDFENWDGRVLDGPAFFDGLVCNHCLAASGPGTERLRSELLGFWLGCANRRLTDLAHRLRSGFMQLYYAVMNVPKKYPCKRIILREIIPGVMDPAFFSCPPHEFVPGSRYFEPPPADLVFYRLRYGQWLDAFERIKDDADMQEFYALREGFLKRQQSILDESYDAAEAHYIWLYKCKKAVLENPQLLVDWALARNGAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8L0</accession>
    <name>A0ABR1W8L0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667300.1">
        <property type="nucleotide sequence ID" value="XM_066811958.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045018"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39610:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39610">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="368" mass="39067" checksum="F2062A7326D3B73C" modified="2025-10-08" version="1">MAPDLNSLPPSSPPPSLPAAVSRSMHSPNSSTEASIAMSGESPPHASRSGSISLQAAATMNAGLQREPTRRSSSGSLSRTRQSPSAGRRRSVVLHNLQLNDPSIPSPGEMVHESTGVAGGHSSVSPQPIMGSPSMSGGSTHHRDRAPSLGELHQELEAEQEAQVNRLLQMIRQQQVQLQHLQAAQGQPQSTVAAEDGTPTSELSSSLPHQQAVPAPLSPYPPLPPLSSSTPRSPVISHPRSSFDINRSERPSRRSSHATSSPRLRSTSISAEGGEPWLLGGGRDESAFYQAETQSLIRENQMLRHRIRELERQVNDPHAHTSVTREPSHPSHLLQSTSISEDNGGGVGPSSVAVTESSTPATSTPKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8N2</accession>
    <name>A0ABR1W8N2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pilus assembly protein FimV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667313.1">
        <property type="nucleotide sequence ID" value="XM_066811971.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045031"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="11161" checksum="A0F85E6C1E0EC55B" modified="2025-10-08" version="1">MPLSTDLLRVELPLSEEPDIDMDLDLVLDLVSEADSEADSESDSDSDSEADSEADFETDFETDSEADLDSDSESDSVLDFELDPEVDVEADLARKGGAVRLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA76</accession>
    <name>A0ABR1WA76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dienelactone hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667885.1">
        <property type="nucleotide sequence ID" value="XM_066812543.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045603"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436:SF3">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="POLYKETIDE CYCLASE SNOAL-LIKE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="56175" checksum="29DB1A7B539AD556" modified="2025-10-08" version="1">MFDVPKIVEAALPEEKRNGRTIGIVGGSMAGAGPNHNDQNFLSDDFPKSKPKLYITAEEDEFDELTIAEWKNEGFDVEYFSLGNGGKEYQSHLRALANQDLGPCETFGIVAYGNAASQCLEYFHIPDNNRSMKLALLVCYYPTSIPDPRTKIPNVDVVVHLAEGDETINIIKQDQMVGIQGKKRTVRRQIPQGMGSGRYVKYNYPTYSYDADSGFAEQDMDAYDKISADLAWTRSLTAARRVWRRNINLERVHEENVQGIQILHQNLQKTMSTYTANTTPHVTFVPTLTGGIDADELHDFYGHYFLHRNPASLQLTLLSRTIGTNRIVDELHVAFKHTEEMPWILPGVAPTKKKVEVIIVSVVTVRGGKLAHERVYWDQASVLVQVGLLDPNLVPDKAKRRGLKKLPVVGREAAHRRLEGNEDEDIEDGEANNELIEDWVEEDEDEGEEQNEEEEGEGGSGQEEDGDEESEQGEDGHDEGDEIMVEQDKAHHSDEEPSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAT0</accession>
    <name>A0ABR1WAT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008428</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668085.1">
        <property type="nucleotide sequence ID" value="XM_066812743.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045803"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="57617" checksum="FACD512D1164E264" modified="2025-10-08" version="1">MGVDMSMNGWQYGHFDLAHASVALLAGYLVYGLLLALYRLYLHPLAHFPGPKICAVTEWYEFYCYIVKGGQWGNQVQKMHERYGKPHGPIVRTSPWELSIRDPEFYSQLYVAASTRRTNMWPRGREGNGFESSHHLSVPHDLHRSRRKHLEPFFSRQGTTRVEHIIKDEAQKLNARLLQLSGSGTIVHLDHAIAAMTGDIIGFTTCGMQPNLIEEANFSPSWYELMVKTTTIAPLFRCFTWLNRCVSSSSFSSGEGMYPEGISNMMLGKAGRLYIERIKRELDGSPAEKRGEKKWNSAFHQLLSSDIPEEEKSTERLQAESMILLLAGTLAGAHTLTFVLFYLLASPVMETRLRTELESTFALAAAAGTGQEMPSWTELERLPYLTGCIKEALSINVYATGRKQVPVGMSIRAMHTDASVFPDPMQFKPERWVGEYDPKMDRNFVPFTKGSRSCLGSNLAWAEMYIATAALFGPGGPKMTLYETDETDIKIVRDYIMGFPKPGTRGVRVRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB40</accession>
    <name>A0ABR1WB40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668186.1">
        <property type="nucleotide sequence ID" value="XM_066812844.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045904"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047521908" evidence="2">
        <location>
            <begin position="18"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="191" mass="20408" checksum="EDD10E15BB7C635C" modified="2025-10-08" version="1">MQFSTIFVTALATVAYAAPSQLSMRENKDAAKQQEDAAKQQQDAAKQQEEAAKQQQQQDAAKQFDLGQLNNGQFKNLDLAYLNVVNNVDLQALAVLAVQQNLNLAAFANIFNAQALDLNAVLQLQQLVQLQQLQQLGLLGGVDLAALQLNALNLGAIGNIGGVNLQQFIGADVKNQVQAVVSGANVIVISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB82</accession>
    <name>A0ABR1WB82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008579</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668236.1">
        <property type="nucleotide sequence ID" value="XM_066812894.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045954"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="30133" checksum="FE70314205BD6F56" modified="2025-10-08" version="1">MSSAVAKRLEGKTIVITGASSGIGRSTAFEFARTAPKDLKLILTARRIDTLKEIAADIAKEVGDGVKVLPVQLDVSKPEEIRGFVEGLPAEFKEIDVLVNNAGLVKGVAKAPEILEEDLNVMFNTNVTGLINMTQAILPIFLKRPNGGAGDIINIGSIAGREPYIGGSIYCATKAAVHSFTDSLRKELIATRVRVMEIDPGQVETEFSVVRFYGDKAKADAVYAGCEPLTPDDIAEVVVFVAGRRGERGGGRYAYLPEPPGGCDRHAQEMNIATTRLTCIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCK2</accession>
    <name>A0ABR1WCK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HET-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667670.1">
        <property type="nucleotide sequence ID" value="XM_066812328.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045388"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="47"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="174" mass="18714" checksum="DB26DEAE2E14E0E8" modified="2025-10-08" version="1">MPEVRSRVSELRGLDPGPRAPPSLCSKAPVEVRIREVSLFEARIIKYEALSYARVGDTKRRGLGGSNKSSSVVVVGSGGQRLPVTDNCHAALVRLRRRLWTRTLWVDAVCIDQAEDEAGAKGAQPPGSAHGPDLQPRIAGRDMARSGGQKHEVAVQGHQTVVGLRKGGEVLQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE89</accession>
    <name>A0ABR1WE89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008236</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667893.1">
        <property type="nucleotide sequence ID" value="XM_066812551.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045611"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="583" mass="64590" checksum="0FA031E6AF7A98D7" modified="2025-10-08" version="1">MSSASLDLAYPFARLPFAASAVIVGVLSVLYLAYHWALPKPLPGIPYNQDAVKTILGDAAEIQQIKKEGGRPRAWFNLQTAKHNSPIVQAFLAPLSKPVLILSDFREAQDILLRRGKEFDRGPRHVANFSGVVPWHHIAMATSNPQFKANRELVKDLMTPHFLNTVSGPEIYNNAQNFIELWKLKAQKAGGRPFRAEDDLHTMTFDIIKVVALGEGDNQSMTALYTDLVRSTAANAQDASSAGQDEPFVFPENEPNVDLRAHGTQQEAVGAAATQPFPGLFHKMNNRKPVMREAFAAKFSMLDRQVSLGVKRMEAGAEVKSALDYMMQREIASAKKAGRAPVFNSPSMYDELYGYIGAGHETSSTSLQWGLKHLAADQRVQTTLRESLRAAYADAVSEGRQPTFAEIIKTQVPYLDAVVEEILRVTGPVRTLFRTAAVDTTILGHHVPKGTQIFLPITGPSFTTPAFAIEESLRSPSSQSHKNMRGTWDESDAAKFVPERWLKTEDDSTQVFDSQAGPMLAFSLGIRGCFGRRLAYLQLRILMTLIVWNFEFGPLPEELNSFDAVDTLTTKPARCFVRLNEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WKX3</accession>
    <name>A0ABR1WKX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668714.1">
        <property type="nucleotide sequence ID" value="XM_066809791.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042851"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23807">
        <property type="entry name" value="UEV_UBE2V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="6"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="140" mass="15765" checksum="7BBF29216ACEC9F8" modified="2025-10-08" version="1">MGAKIPRNFRLLEELEKGEKGLGTEACSFGLADSSDMLMSDWNGTILGPPHSVFENRIYGLKMHCGEQYPDQPPTIQFIHKIILPCVEEADGKVIPSKLPCLANWKRENTMETILIELRRFMASSQCKKIPQPPEGTTYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL64</accession>
    <name>A0ABR1WL64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668804.1">
        <property type="nucleotide sequence ID" value="XM_066809881.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042941"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="325" mass="35134" checksum="31A79DC1FBCA39DF" modified="2025-10-08" version="1">MLETHHRWPEATRKRGREEEDNGSAESLSFGDHLAATTITPTDSDSEEMQSQSHFSPWVSTLPMQQQQQQHASNSSMEVDRDTDMMEGMANAPDQSMGDGYGASNTGRIPTPINATFAAQVRGNNWTSANQQMHAANSNFGVEQFQNQMGSAGTGAGQHHAFPPAADPSVPRSLDGSAGWSMIQNRRLPSPISESGGEELPTSPGMVLDASQQRPYLPHMPHSTNPAAMAALHPNLEICHEPATEADTGMMDADGDVCSEEGNSPSSAPATPSPRSKYGHSRSKHTVNSWTLQPGMKKSFSIGYRADCDKCRQKIPGHFNHIIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL96</accession>
    <name>A0ABR1WL96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Leucine-rich repeat-containing protein 40</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668818.1">
        <property type="nucleotide sequence ID" value="XM_066809895.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042955"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF27">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="268"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="790"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1078"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="840"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1082"/>
            <end position="1091"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1097" mass="119344" checksum="E3E00F4162024D4D" modified="2025-10-08" version="1">MDDNKRLSTASNRLSAIPRPTSRLPVPRSSAIQTTTSWTTANGLRPAPSRESLRPSSSSNDVRSTTTNSRLRSSVSRDQLDAPATTASANSFRKPQRPGGPPIGSQGTLQGVKSRSVSRDPLSRITGDTRSQQPIAIRKRQSSVQLAGNYGRDGSPMDEENTPEMPPSRKSSMGEEASSFDTLKTPSRNSRPSLSERTIETLSQLPSSPVIKRNGSSFYDNDGFYRPASRAGSGGPGQVPATSLMDPADRQEGRQVVRDPALALPIISIQTSEPQPPLTGRHWPPRPLKQRASVNGLFKKPSMSSLGKPEVVSELHPRPTRKISQVSERSSTTSAEDHHPSNASTASTALTSDSVEEPTSVAAQKSSAALRERIAKAKAAKRAAAKQVSAAALPPTEEAPLVPTDTSFDFGLAGDPFNQNQFETSNRKVMQTRINGARTTGKLNISAMGLKEIPEDVLKMYDLESIGKHGGSWAESVDLTRFVAADNELEVIDDSIFPDTDPADFADEEDGNGHQFGGLESLDLHGNTMISVPLGLRRLQFLTSLNLSSNKLANNCLEVISQVTCLRDLKLGNNLLYGAMDPCFSKLENLEILDLHGNEITALPEGIENLTRLRILNLNENAIDSLPFKAFAKLPLIELLARKNRLSGTLIHPEVESLPQLQILDVSVNQLTLLASVDTPGALAMPSLHQLTLSCNRVRALPDVGSWKRLLTLNADENSIAAIPDGFTKLENLKHVDFTSNDIRVIPPEIARMDSLGMLRLSGNPLRDKKFTSLTTEELKSNLFARLEPPADEMGGIQNFSNGIDASSRPRKASNAVRQGVSAHNDDDESRSEHEDNFATPPTSAPHSPARSRSHTLSGQTWPVKTGGILDRSNTQSSSLHPVVCSKMAAEQTIRDIRLGNNTFTTLPNSLSFFADTLSSLTIAHNQLVGESYLGEELDLTALKELNLSHNHITSLGPLTAHLRAPNLQKIDISFNRIVSLPRLREFFPSLTVLLVSNNHLEDLDPESIKGLKIVDANNNDIPHLNPRLGLLGGAGNLERLEVNGNRFRVPRWNVLERGTEATLRWLRGRVPVAEMGEWKNKGGNNAENEGSTNDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLE1</accession>
    <name>A0ABR1WLE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">nitrilase</fullName>
            <ecNumber evidence="4">3.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005588</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a nitrile + 2 H2O = a carboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21724"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18379"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="EC" id="3.5.5.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.5.1" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668826.1">
        <property type="nucleotide sequence ID" value="XM_066809903.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042963"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07564">
        <property type="entry name" value="nitrilases_CHs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000132">
        <property type="entry name" value="Nitrilase/CN_hydratase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044149">
        <property type="entry name" value="Nitrilases_CHs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044:SF14">
        <property type="entry name" value="ARYLACETONITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044">
        <property type="entry name" value="NITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00920">
        <property type="entry name" value="NITRIL_CHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00921">
        <property type="entry name" value="NITRIL_CHT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="6">
        <location>
            <begin position="9"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00036406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="34856" checksum="C19B6F2F289A9716" modified="2025-10-08" version="1">MADSKKTPLRVAVTQAEPVWLDLDATVEKTCALIAEAASNGARLISFPECWIPGYPAWIWDRPVDPEMIVAYTRNSLSLESAQMDRIRASAAAHQMVVVLGFSENRQGSLYISQAVIDADGEVAATRSKLKATHMERTVFGDASAECLAGVTETAVGRVGALNCWEHCQPLLKYHMYTQREQIHVSGWPPVDPHQGPELWSMSREGVENLSRTYALESQSFVLHTTTVLGKAGIERMKTQNSMLMATPGGGCSAVFGPDGRKLTTDIPGGEEGIVYADLDFDAIIMAKSFLDLCGHYSRPDLLWLGVDKDVKNVVREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM59</accession>
    <name>A0ABR1WM59_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005838</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669076.1">
        <property type="nucleotide sequence ID" value="XM_066810153.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043213"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052349">
        <property type="entry name" value="Metallo-hydrolase_Enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027:SF0">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="452" mass="50058" checksum="4BD768E1840A5DC9" modified="2025-10-08" version="1">MKLQNVVLTEGPGDARWDLEILDGVLQTKEATKADRDVPSGILLPPLCHPHIHLDKPYILTCNHAPSDRHPDYSDLAPQSGSFGEALANTSKAKERYTAEDLHLRGSQLLATSHQQGVTSMRAFVELDHVTGTLPLQAAIRLKQDFSHLVHVQICAFAQDPVFSTEHGEKNRSTIETALRDLGSFVDVLGSTPYVEQSESDSIKNVDWAIRTAMEHGLHLDFHLDYNLDSSATFLVESVIRLLEEHQWTRRADKSKTIVIGHCSHLTTLPSRRIRDMASSIRQQNLPLHFVGLPTSDLFMMGRPAEKQTRPHSRPRGTLQVPSMIQDFGLSACLGVNNVGNAFTPYGTGDPLQLACWGVGLYQAGTVGDAELLFSCVSSRAREAIGLSNVGYEGVLKEGSRWRPMLLIENIKMMRLRPKPGHADFPIPARPRISIKDIVWDPPETSLRSVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMC0</accession>
    <name>A0ABR1WMC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005956</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669194.1">
        <property type="nucleotide sequence ID" value="XM_066810271.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043331"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF31">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="26"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="376" mass="41106" checksum="65FBD19950CE9919" modified="2025-10-08" version="1">MVAATSKDMALAVLVPLPLNILTIVARFWIRTQRKAWGPDDWAMVATIPVWVVSQVGMIGMAWSGVGQLDSTLTAQQKANSNFWFYVFQEFWCFTLVALKWSLGFTLLRIGDGKKWVQGIIYACLALVTICTGGTGMYLFFQCTPVEKNWLPETEGTCQPREIQTALSFLVAAVSITTDWIFAMLPFALIWKLQMGARVKASVIGLLGLGIFASIAPIVRLKYLLLMNDASKFLQGLGIILAWAQAEVGIGLLVANLPACRPLLESAIAAFTSTISSKDKSKTGATSAAAKNSYLELGERDPTKKGNSMASRGGVETKVYGTYIGDGSSESLPQPADSRERIVHKQSQNQIHVQTEFGMEFENKQRGNSHHGHGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN09</accession>
    <name>A0ABR1WN09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cytoplasmic tRNA 2-thiolation protein 1</fullName>
            <ecNumber evidence="2">2.7.7.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Cytoplasmic tRNA adenylyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NCS6</name>
        <name evidence="2" type="synonym">CTU1</name>
        <name evidence="5" type="ORF">PG997_006196</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669434.1">
        <property type="nucleotide sequence ID" value="XM_066810511.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043571"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="CTU1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03053">
        <property type="entry name" value="CTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056369">
        <property type="entry name" value="CTU1-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000541">
        <property type="entry name" value="Ncs6/Tuc1/Ctu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020554">
        <property type="entry name" value="UPF0021_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807">
        <property type="entry name" value="ATPASES OF THE PP SUPERFAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807:SF12">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01263">
        <property type="entry name" value="UPF0021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="4">
        <location>
            <begin position="53"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="292"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="321"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="393" mass="43039" checksum="2F3F17F9085999DE" modified="2025-10-08" version="1">MAPALCAVCKTERALIKRPKNHQKLCKGCFIEIFEDEVHHTILSSSLFYPGEKVAIGASGGKDSTVLASVLKTLNERHKYGLDLVLLSIDEGIKGYRDDSLETVKRNAAQYDMPLKIVGYDELYGWTMDQVVETIGKKGNCTYCGVFRRQALDRGAKMLGIKHVVTGHNADDVAETVLMNLLRGDLARLSRATSIVTGSNASDVKRSKPLKYAYEKEIVLYAHHKKLDYFSTECIYSPEAFRGSARTLIKSLERVRPSAILDVVRSGEDMARLVPGQTQDACACKANATSAPVPAAEEDNGSGCGSANGRSTGGEMAAMERQLKEDEKAAEEKLETEITIPKPHAKGSRPKPEKESKASSITVPIMKQNWAHARDAATCRVRSCARRACFLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPR9</accession>
    <name>A0ABR1WPR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nonribosomal Peptide Synthase (NRPS)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006816</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670054.1">
        <property type="nucleotide sequence ID" value="XM_066811131.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044191"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19545">
        <property type="entry name" value="FUM14_C_NRPS-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="738"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="1289"/>
            <end position="1362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1818" mass="200215" checksum="70878D1ACC0CD5D5" modified="2025-10-08" version="1">MTYATITPIFRGGGGGGDSQAQVSNFIEALKFSYSIALHHFHDTNEYVVFREDINLSGTIIQNGDAKAKKSRGIGKRIAYDPHMYQNVSCSEALENSCSSSSGDVDVGPLTSQVNGEKGTSPTSTPYLMVLDCDPPAPTNNEAQYDDIGMRGFARTLEKLVDTMAETPSLPVASLKLAGSTDCQTIGNWNREPTIAEKACLHHLVERTARNRPDEPAIVSWDGTLSYRELDSLAGRLASHLSTSYAVGPGKKVPLCFEKSLYMVVAMLGVLKAGGAYCCLDPAHPRARHEYIIRSVDASLIIASPHQDHLFQGIPAVSVLTLDARTLDTLFPTAAADSFSCGTVGPDDTCMIAFTSGSTGVPKGIVHTHSTVTTGLVESAPRQRLDQPGTRVFQWAAYTFDVSLSEIFCPLLHGGVMCIPSEDERLNDVEGAMNRMRCEWAFFTPTFSRFFRRYDVPTLQTLAMGGEAVMNDDINAWVGRVRSVLQVYGPAECVTWFIKEYTEPTYTTISFGKATNAHLWIVDPDNAERLMPVGAAGELLIEGPAVHVGYLNDAARNEAAFVQSPPQWRKAIGAPCTDRIYKSGDLVRYLPGGEMAYVGRKDAMVKLRGQRIDLGEIESVLRVTLGDTADVAVDLVVPAGKNRDQALVAFIRIREQAAPAQETLAPLVPSLQIELRKNLPEFMVPRIFYPMEELPYNASRKLDRKALREFGSSLTIEALMKQNAAAAVHTNGTQQHPAVLTPAEQCFQKLWADLLHVEQSDIKLDDNFFALGGSSLSAIRLIASARDAGYSITYTTIFKSPTLREVARSAIPKVEQQSAAAIEPFALVREDRRSAVLETASTQCAVATADIADIIPITPQQEGLWALSLASDGNDGSYIAHFTIRLREATDVARFCAAWETVADNVAFMRSRFMQSNAGAHQVVLKNAVAWKEGLSAQEFVRSELQEPVDFGKPVTSYGLIRDEPTLNPVLGFSNNLVVWKSHHGLYDGHSIVLFLNAVAQVYRGETFGPEVPFPRFIHHLQTMDERACRNFWRSRYEGPRPSGYYRRSITFQQPDHSRITKANVLRGALALTIAQVTGASNVNFLETLDGRSVAVPGVESIIGPTFNTVPRNTAVDLGLTVEQFLLRMQDTSTEMMPFSLYGLQKIHTLSPQCASACEFQSLLVIEPSYLREYTDVFDFDETGGGIHRFTSDCILWKCDMHDAGVELGTSFDEHVIDAKELRWVVNLFEENLYFLCSGEQSLPLSANPATLIASHVFAHKTTSNGVATAPEPPATNGTTSALMNGSGGQVSQLLSKAWIKTLGMEEDEFSLTDDFFLKGGNSIRAMEFVAAARALGISITVAKVFQNPSFHALVKVAALQNIERDDGSLPFSTIGPQYTKDELIRFAVTQCDISPSEIEDILLATPLQAGFMASSVRKKGAWMAQTQYTFPRDIPVEMIRAIWTKLHEHYRTLRTRLVQTSSGVYQVVTRSPPLWLVFDDHSVYMNADREMTMKYGDALTRYAIGSPAVTDGRRRSIFTMHHSIYDGFTLDKLHHALNQEMSGYQLHPVPTSTLFMRHIAAIDEAAAKTFWQRYLSGYSGSDAFPPRVSASHVPEANRTLKIGINLPSHREWPSITLPTIILGAWALVAGHYSGETEDVAFGTRVSGRCAPVQSVMDMLEPTIAHVPVRVKISRDQSVENFLHRLQIEQSEVMAYEQTGLAKIAAYDEHCRAACSFQNMLVIQRPSDEVVDELGQRIGVYEELSDYKYFNDWALLVDVFPSLAGDGAQLVFCYDSSILSDERIKEMAQRLERAIALLASSKDGIAGTTEAIGSDIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPV0</accession>
    <name>A0ABR1WPV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamate-5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="2">1.2.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006848</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670086.1">
        <property type="nucleotide sequence ID" value="XM_066811163.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044223"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001221">
        <property type="entry name" value="PRK00197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063:SF8">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063">
        <property type="entry name" value="GLUTAMATE SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="451" mass="47945" checksum="E1B61326E01BC1FF" modified="2025-10-08" version="1">MSLTSSSAADAARDAKSASHVLATLPAAARNDALTAIHAGLEAGRNEILAANARDLEAARRQAADGAPLSQSLVSRLDLGRKGKFEDMLKGILDVRGLEDPVGKVTLRTRLDEGLDLERVTCPIGVLLIIFEARPEVIANIASLAVKSGNSAILKGGKESTESFKAISKVISEALTKTQVPNGAIQLVTTRDVIPQLLDLDQYIDLVIPRGGNELVRYIKSSTKIPVLGHADGLCSMFLEQSADPKMAAEVIVDSKTNYPAACNSLETLLVQESALDTLFPAAAEALLAKGVMLRCDPKSKAALAKTSFASEHGDKIVDAKDADFDTEFLALELAVKTVSGLEEAVAHVNTHGSKHTDAILTASPELAERFMNSVDAAGTYWNASTRMADGMRYGFGTEVGISTNKIHSRGPVGLEGLMIYKYKIRGRGQVAGSYGEGDGKKPFLHERLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRE9</accession>
    <name>A0ABR1WRE9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ZEB2-regulated ABC transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_006356</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669594.1">
        <property type="nucleotide sequence ID" value="XM_066810671.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043731"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="891"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="924"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="965"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1010"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1040"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1070"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1162"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="553"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1193"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1194"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1225"/>
            <end position="1235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8085085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1243" mass="139603" checksum="A0EE9A1D65ADC15D" modified="2025-10-08" version="1">MAMFGISHTINTRVGNEYPRPLQCWDNSTRGLDSANAVEFCRTLRMQTELFEHTACVSIYQAPQSAYDLFDKVAVLYEGYQIFFGRANLARQYFINLGFDCPARQTTPDFLTSMTSPQERVIRSGFEGRAPRTPEEFATAWKNSAEYEALQKEIEEYKNEHPLNGPDAEAFRASKRQAQAKVQRAKSPYTLSYVQQVNLCLWRGFRRLIGDPSITIGSLIGNTIMGLIIGSVYYNLQPVASSFFQRGALLFFACLTNAFASALEILTLYAQRPIVEKQSRYAMYHPSAEAVASMITDLPYKIMNTIVYNLILYFMTNLRREAGAFFFFLLISFSVVLAMSMIFRTIASSSRTLSQAMVPAAILILALVIFTGFVIQTDYMLGWCRWINYLDPLAYAFEALMANEFHGRQFTCDDKLQLPAPIGPYASPDLGPLNRVCNAVGAVAGESFVDGDAYIAKSFRYYWNNRWRNFGIVLCFITFFLLTYMVTAELISAKKSKGEVLVFRRGHKPAQFKEKKGDDEEGMMRVGPTATNDRATATARDSTAMIQESSSVFHWSNVCYDVKIKSETRRILDHVDGWVKPGTLTALMGVSGAGKTTLLDALASRIKMGVITGEMLVDGHLRDTSFQRKTGYVQQQDLHLSTTTVREALNFSALMRQPNETPRAEKLAYVDEVIKLLDMEEYADAVVGVLGEGLNVEQRKRLTIGVELAAKPPLLLFVDEPTSGLDSQTSWAILDLLEKLTKAGQAILCTIHQPSAMLFQRFDRLLFLAKGGKTVYFGDIGENSTTMTSYFEKHGAPACPHDANPAEWMLDAIGAAPGSHTEVDWHQTWRDSDEYADVQAELQRLKDEAPDGPPPTEDNSSYREFAASFQVQLKETTHRAFQQYWRTPNYIYSKALLNTLVALFVGFIFFNAPNTIQGMQNQTFAIFQLLTVFGQMVQQTMPHFVVQRDLYEVREQPSKVYSWKVFMLAQIIVELPWNTLMAVIMYFCWYYPVGLYRNAAAADQITERGALMFLLILAFMLFTSTFTDMIIAMFETAESGGNMANVLFMLCLIFCGVLAKPDTLPRFWIFMYRVSPFTYLISAMLSVSIANTEVVCADNELLQFNAPAGQDCGTYMAPWIQGAGGYLQSNTTSECKFCPIQSTNIYLDQIGSNYADRWRNFGILWAFIIFNIFGALFFYWLVRVPKGAKKEKLGSNNFQKTNSRASKAGSKADGRSLKTTPSHVAAPASKAGPSSAEKETSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWQ9</accession>
    <name>A0ABR1WWQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670487.1">
        <property type="nucleotide sequence ID" value="XM_066806869.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039929"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="21"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="205" mass="23122" checksum="4581BB85D386474F" modified="2025-10-08" version="1">MSDRIAELEARVVAAERLAQRAYDRGAVENVFSRYMHLHNVFLDEQIKPLWVARGTPGIRAQYTNVGVYTDYDSVMAYHTGRPAPAGKLILHQTTTPAIEVAEDGETAKGFWLMAGLESGLTEAGNVGAMPEDLWAHWVWCQYALDFLKQDGEWKIWHFRCLEVSRAPFSENWITFADKNQVAFEKASLDPDPQTKCFNSGGHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWU8</accession>
    <name>A0ABR1WWU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670483.1">
        <property type="nucleotide sequence ID" value="XM_066806865.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039925"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="85" mass="9466" checksum="1A736CD1DB9570D3" modified="2025-10-08" version="1">MAMFTLALVTVLFLPGTFVAGLKSILSTSFFNYDGTTFTVSDNIAPVLVPSLIGATLLILLSWFAWYQWRLYRLNRKTVGSNAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWV6</accession>
    <name>A0ABR1WWV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670549.1">
        <property type="nucleotide sequence ID" value="XM_066806931.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039991"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="33071" checksum="3A21D154D8172396" modified="2025-10-08" version="1">MEVRDEVAELHISMVDYKLHFAYNIIFTLAVGFIRLTLLVLFLQLFLHHPLYRVVQGMIVLVVVWVACYIVMAFSCGKAPTSVVSPYDVSSRLCPGFRLGAAAQQKIGFSVALTDCVIDVTMFLLPLYPTPGSSNRKETPPGVSGTIAWWTMTECSLGNITCNLPIISGYIFRRFFSARVTYVSSQIVTIGRKSLRLNPKGPPDQTLDLTLDQTVLQQTRAAAATEDGISPSTIEHVEPSPLEIPRGQAIPRNKSKVRGRQDRETAGIPITTKSANPLAVGVHLFKWAVVDINVFRQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX35</accession>
    <name>A0ABR1WX35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670573.1">
        <property type="nucleotide sequence ID" value="XM_066806955.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040015"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="109" mass="12394" checksum="676ADE94330F9755" modified="2025-10-08" version="1">MEWKTEMRSVLGTQAGGSVQTAAMLPLHWKSGWSPATVKAFLNEAERVLAHKCFIFVKIWTVQRAALYEAHNEDLYRARFTDKSMEAMRTSQNLAQLHEAIDGLAEEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX79</accession>
    <name>A0ABR1WX79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_002694</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670627.1">
        <property type="nucleotide sequence ID" value="XM_066807009.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040069"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02878">
        <property type="entry name" value="GH18_zymocin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF2">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="11 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0843">Virulence</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1048"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1077"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="15">
        <location>
            <begin position="358"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8087733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1110" mass="120358" checksum="6B8CDADBEA9DF32B" modified="2025-10-08" version="1">MAAGASSPSIPSLDGCPSVCSSTAYASWTLYEDIQRLRLCDRHMRLEFALGGGNDKQAEDIAVLACTLDERSLRPRDSITIDSNTLCVTDAGPVSVSLEVAKAGDGMNFTFVTADALAQIASYMGADCDMKQTFSYGLGTLVGVFSGAAVDNGGSVSTVLSEAIAIANNSDTGAPESMFLQRCPKEGNSKHIFGVAINNGGDFDWVQSAIQSWSNGDCLNSSSLKSPELSVSNVTFYEYTHPPTNLSSIVPNNLTATLTGKGAGTSLTPTVSRWINFILGTQLLDSVRSAEYGLTNQKIESFNNKTTWGWFGCNNLPALLTICLSPAGNPGTAPKGENGCISHCGTEIVNKGSGPANVISIGYYESWNWDRPCLNMRAASIDSSQYTHIHWAFATISNTYEVVINDSYSQWKDFKDIHVKRIVSFGGWGYSTEPATYDRLRQAMTPSNRNSFINNIVNFLNKEGIDGVDFDWEYPGAPDIPGIPPGLPSDGPNYLAFLTALRGKIPSGKTMSFAAPASFWYLKQFPVKDMAKLVDYIVYMTYDLHGQWDYGNKWAQDGCETGSCLRSHVNLTETMLTLAMITKAGVPTKQIAVGISSYGRSFKMAQAGCTGPLCTFTANADNSSQAEPGECTATPGYISNAEINNIIIANTSTGVKSWYDSKTDSNYAVWGGTQWVAYMTEDVKASRKSRWQGLNFAGTIDWAVDLAEYTGDDGSADGSCDPEEDEVDDCPDDGAFGAPLVTCDDSPSGHFDDLSDSTIASWPVECAPQYTLQLLAGLLKDSMSQYDDLMKQHYDKKFKVYAKAVAGSANKQFHDFMMKHSNEYFTCENEEEVVVEEEEAQDMDENFFSNSTYYSIIQRRGDYYPGMNRHLVTSMKKIKEPCPPDYSQRGYGPKNPYHQSVYWTLDSSKADAFYAALLDETGVPKSKVGFGLHTNADMCSGSGHKVGDGASCWDTGYEFAAPFPKDYGAEDVTNPKELAQKGLSNSADLPGQLADAVAQMRTDTYLGASGYDVVDAVALPILMIVQGVESMAMVVQTADKIEEEERKAIILAFISAILFFVPIAGEVLGTVAELADIGAIISVMGAVGNAAFDVYTIVDDPRTRPWLSWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXE5</accession>
    <name>A0ABR1WXE5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670661.1">
        <property type="nucleotide sequence ID" value="XM_066807043.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040103"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="73" mass="8395" checksum="5FD9D37D78B5BFAA" modified="2025-10-08" version="1">MEHRSEARELPLLDQRGAEWCEFVPLLIIAGRMSLPEELEGSAAGIYYAVSDQERVRWVVRSREARDGEEDYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXG7</accession>
    <name>A0ABR1WXG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670735.1">
        <property type="nucleotide sequence ID" value="XM_066807117.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040177"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="38"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="332" mass="36318" checksum="C17B2775A95B3588" modified="2025-10-08" version="1">MSEQQIEKDAQGYSPATIADRTSRTVDSDASFLKPYLKPSDRILDVGCGPGTITCGFSRLVDSTKGGHVIGIDSSKETIQRARELARTAVPATIQLGNGNGHITSASFGNGATIQFQKEDKLDRLRFVDGAFSVVHANQLFAHLPTAWHRTSALREMRRVLKPGGLLATCDVAELHFYPPRCEIDGVWAANMAHLLSRRQEDACLPGGHMPGLFRAAGFGKPWIEVKKEGDEGDDIYGNGKGRAAAYTKISEDGGKMVVGAGATVHSGREDVKWFADSVIGRLQPGDTFRESWRRAGITDDEVERTCRALEDWGNDEDAWYVALQVEILAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ54</accession>
    <name>A0ABR1WZ54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671331.1">
        <property type="nucleotide sequence ID" value="XM_066807713.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040773"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="65" mass="7485" checksum="237D08949C381F36" modified="2025-10-08" version="1">MGQPRSRSYRRKKDYKYSREASNAGRVMVDDLFGGRETEPGCSRIDVRPLTPRFQTNTISYKAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZE4</accession>
    <name>A0ABR1WZE4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671427.1">
        <property type="nucleotide sequence ID" value="XM_066807809.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040869"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="85" mass="9350" checksum="2E269B0D8257997B" modified="2025-10-08" version="1">MSSPESHGLPDPAIKAAHDGMHHFEQEQHERDAAAKRGLPDEAIDADREFMQGVERRASESSQTSATKSGSKIKRAIDKMMPGKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZH5</accession>
    <name>A0ABR1WZH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671462.1">
        <property type="nucleotide sequence ID" value="XM_066807844.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040904"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="15305" checksum="33A31B262F4362A9" modified="2025-10-08" version="1">MQPARRSVHDNPPRARSGGWGAGAGATHSNRTPNDREKGKAARPRRHHDSSSPPPARALVRWNMVFTWQAPMMLLSYSIVAFLTGVTVYVCTPLYADDDTLGGRAAAYFYLSWFSVAAAVFVWCSFWAYKFVDLDHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZR3</accession>
    <name>A0ABR1WZR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671514.1">
        <property type="nucleotide sequence ID" value="XM_066807896.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040956"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="52387" checksum="DF43882D1022A90B" modified="2025-10-08" version="1">MAPVPNLYPPSYAPLGVAVAHLSLVVYLSYAVGTSLYTSYKALSPVWADHRGYALPQRVFGNEGLLPSPNNSSDLYLAHWLSDTPVYFDALEIIAEKARRFWWGQQIDLATVAWSMLLAIEGRRRRIPMLSAFMALAHLVNLSYAQNLFYLALLLTPAPIPSGENDPKLPAAPASIWTKLHNYFFPPKPNNWCPHPVVLLTVVAVNLAAIGLLPHAAETPSFVKVAMIARLATFLPLLLPKVVPDSWGTVHPHPHNAYSSFTTLFRFLSAASFFLHAKATFYGLSYNIPNSHYHRHSRFIPWDVEERSAWERGSSSVGKVLGSISDHPVVAAVGWDALICAVSLGVWAAVRATDVQAIIKSAVPYYGTDIAEALPSKEAILDKMIKTEPEGDESPEPESYMSKQSGQNKGRLASIASSSGLSEDVAASTPRRREAREVVEGDILPPEELDWESASLSWGFAALGGLGCACAGVFGGESISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZZ3</accession>
    <name>A0ABR1WZZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671643.1">
        <property type="nucleotide sequence ID" value="XM_066808025.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041085"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046655391" evidence="2">
        <location>
            <begin position="18"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="652" mass="67617" checksum="79EEF22F7DB43908" modified="2025-10-08" version="1">MHLLWIAIAAASSFGAAAPLECSKDECFRAVDQVSSRIRASDCRSLFEVTVTPATSTVLRTVVVQTTGTRTKTILSTDKIAAATAPSKRWQDQRDIAGALLRRSETEISTSPPQKTPDYAAPCGSVNAMSSVCSCMGYEQATITVPAPETTRVVTLHEPAIVTAFKTVKTGQKFPAPLNSTSNVFRNSTAARFGNSTAKAGNFTFSGSASRSASAPNSISLTSLSDSTQAFASSAMPGRTKASGTSRATAVSAMSTTTGSVMGSSGQPLPASPSSSQLPSDTGSKTIHSSIANKAPSTKTIATSAPLFANNTITRPNTTISHTSVSLTGSGRFANTTKPAVPFGASSTASFSNSSTSVSVFHATSTTAKFNSTSVPVLNATTPAPFLNTTILPFASTTLPPFVNSTAPGMLANSTSMQSSNATKPPFAYANATTSAPFLNSTIMPFANATTSAPFLNSTSIPRFNTTRAPYANATTFRALNATSVRFSNTSAPTPTTSAMTCGETASPFMLKVSQPSGLFDGWFAKVLANTIIFTSSANHSSKFSVESSGYLCAVGYKGEDGNPTIAIVEDKKDLTGSAVYLVDQKRMEDLSKQGYGTLDCAVNGDLACQGGQDYKNWVGCGLGLDISSDDGENVVVDGWNCTSVALSAVYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1A9</accession>
    <name>A0ABR1X1A9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672112.1">
        <property type="nucleotide sequence ID" value="XM_066808494.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041554"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF0">
        <property type="entry name" value="PROHIBITIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="26"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="278" mass="30735" checksum="EF3AF9BFEDCF49D9" modified="2025-10-08" version="1">MEARILSAVYRLGLPVFGAAALAQQSMYDVRGGTRAVIFDRLKGVKEEVISEGTHFLVPWLQRSIHFDVRTKPRNIATTTGSKDLQMVSLTLRVLHRPEVKSLPKIYQNLGTDYDERVLPSIGNEVLKSIVAQFDAAELITQREAVSNRIRSDLMKRASEFNIALEDVSITHMTFGKEFTKAVEQKQIAQQDAERARFIVEKAEQERQANVIRAEGEAESAETISKAIAKAGDGLLQLRRIEASREIAQTLATNPNVAYLPSGSGKNGGQFLLSVGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1B7</accession>
    <name>A0ABR1X1B7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uridylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004093</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672026.1">
        <property type="nucleotide sequence ID" value="XM_066808408.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041468"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="41"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="305" mass="33155" checksum="78407DD7919844AE" modified="2025-10-08" version="1">MQRLLWRQAATRASSRFCASSASASTRSFVSSSSASRVSRAAATKATTPISSPTYPSSARRAYSSQPPPPPNQTVKFWPFLIIIAGGFAGYVFLVKRRVDMPATDASKTAAGRIGAPAKSTPTFNPDDVTVVFVLGGPGAGKGTQCAHLVKDYGFTHLSAGDLLRAEQDRAGSEFGEMIKDYIKNGLIVPMEVTVQLLENAMTATMDQAVKFEESVCPAKAVLFYDCPEAEMERRLLDRGKTSGRADDNAESIRKRFRTFVETSMPVVDAFEKQGKVIKIDGTAKPEDVHKTTQQRIEAKLGREF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3M9</accession>
    <name>A0ABR1X3M9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="2">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004979</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672912.1">
        <property type="nucleotide sequence ID" value="XM_066809294.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042354"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069:SF3">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00070">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="9">
        <location>
            <begin position="5"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="167"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8090018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="217" mass="24250" checksum="A1E69506E685F51D" modified="2025-10-08" version="1">MLPVELTLVVAATRDMGIGRAGTLPWTGLRKEMAYFARVTKRLPADAQPPAMNAVIMGRKTWDSIPTKFRPLKGRLNIVISRSHPEDAPAAVDVEKEPVKVSSLAQALEYLKTQTQQTQTAAAKAFVIGGAQIYGASLALPEARRVLLTRVMDDFECDTFFPLRLSPGEQEEKDKDGKKWAQRSKEELDAWTGETVPEGVQEENGTKYEFQMWERVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3Y6</accession>
    <name>A0ABR1X3Y6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005089</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673022.1">
        <property type="nucleotide sequence ID" value="XM_066809404.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042464"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19953">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1286"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1295"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1326"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1339"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1396"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1429"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1440"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1504"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1521"/>
            <end position="1547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8090128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1559" mass="173298" checksum="AB077806AB885C25" modified="2025-10-08" version="1">MARTRDQEPEEDEQMEDEELVDLQFNETLTWRAGKPIATSELLRRLEKLSKELVDMEQDTVNKESLHDVSKQLASHNLLAHKEAGVKAYTASCLVDILKLCAPDAPFTPSQLKEIFNLFIKVVLPALWDPTHPYNKQHKYVLMSLADVKSILLVNDLPNAEDLLLFLFSSVFDGISGAAKSTSGEQVAKDVEYHMTEILVTLVDEGQGLPPTVLDVIMAQFLRAAPPGGAKNKSELNGNQTTLLPKQEPEAYVVAKTICNSCQDKMARYVSQYFSDVIMDVTTGKAATNGNDDEGGSEDDEPAGPSEADFRELRKAHLLLRELWRAAPTVLQNVVPQIDAELSADNIQLRLLATETLGDMISGIGAAGPPPAPALDPAAYPPLGLDDDGPEHPELSILNTPISPLSFTQTHPQAFHSFTGRRNDKSPLIRAAWTTAAGYIVSTSAGGIGLSREDESTFLNGLRDRLNDNDEKVRLAAVRSIEVFNFRDIVMKLGSSGGVDKTESLLSTLTDRCRDKRPAIRVEAMALIGKLWAVATGELMAGNEIANVLSSVPTYVLNAFYANDPELNLLLERVIFDCLVPLSYPPAKGKGFKANGNSQSQAQSQLADQAYDPDKIRAERILLLVKCMSDKARRAFFAIQTRQPQFALVVENYVRQCEAWNGGTPERNAEMTKQNLKKTIHYICSFFPDQPKVETDLYNFASLNDRRSYQLIKFVISLESDFKTMYRAIKEFNKRVQGSTKPQILDTMVPLLYRSAYIMFNKSHLSTFIECSKNDKNGLGPAAQQITNEISQHLPDLFKTHIGELCKDLIESAPTATKENDVSVVETLKACSSYSRKYPENLPEDRKFIQALTNYALYGQPPKAAKYAVNILMARKNDKSMVAATDLLGRITKDWGPGKPHFLNKLAAVSQLELLAPKVAADANDQIMDMVLQNVLQKVRTEATESDPEWVSDSDMDEECQEKCYAVKVIVNRLRGIQEPSEAKDVTLMTFKLLRTLTKRDGDLCKTTDTPAHHRSRLRLLAGQSVLKLCTAKQFEELFSHSEFNRLSILTQDQCAEVRRGFVTKLQKYLVNGKLRPRFYTMIFLTAFEPSTEFRQQIETWIRSRARHFQENKQTVMEATMGRLVSLLAHHPDYNCDANDLMDHARYLVYYLSNVSTEQNFGMIFKYAERVKQTRDGINAAESEKLYVVSDLATAVLRKWQERRNWSFQAYAGKVGLPVGLYAALPDHDTAQKIAEKQYLPEGTDERLDELLRSLDKKKVRRSQLPPHNPFLQFVLRVDIIGPQKRKGIDERGDGNQSAKKTKLTQSRTPRTKSTKSARTPTTKRSAAKAKSSGRSRKAASSSSPGPESGERRRSGRSKANSSYIERDSDQDDEDMLEGVSKWEYYDKTGNKVGGDDDSDSESTLTEVEEEGTEPEPMEEDGEDDQAEADSKAPGKDAAEDSDLSEPPAEDPEDEVEQVEPEAEAEDEAGDEDEAEAEDAEEEVEEEEEEPQPQPRASARKGRSAASAKSKTPPAKPAKPAPKAAAAKGKSAAASKAKPQPVASGRATRSRRAAADDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4D2</accession>
    <name>A0ABR1X4D2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673158.1">
        <property type="nucleotide sequence ID" value="XM_066809540.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042600"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="122" mass="14045" checksum="0E4B936A66EB2181" modified="2025-10-08" version="1">MPPYGYYGPPVMAPGMQQVQPPSHSLFDHTSFKPGKQRKQQHGGRDGEKYSQTTTQQRNRSGSVHDNMSQERNGKSKRGKNKRVDNRFAPNDMMWDRSRGQFPTERGERIDMQPPFPLNSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4M3</accession>
    <name>A0ABR1X4M3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005304</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673237.1">
        <property type="nucleotide sequence ID" value="XM_066809619.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042679"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF5">
        <property type="entry name" value="CBM1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="8">
        <location>
            <begin position="43"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="342"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8090343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="489" mass="51621" checksum="0E6D607BB3BFB511" modified="2025-10-08" version="1">MALAKVQYLDANVKKGVSIAGGDFGCQTDGTCALSSAQLPGDGADQMKHFVGDLGMNMMRLPISWQFLVNNQLGGDLDTNNLGKYDQMVQSCLKTGAHCMIDIHNFARWNGGVIGQGGPSDDQFVSLWTQLATKYAKNDKVAFELMNEPHDLDVNIWAQTCQKVVTAIRQAGATSQMILLPGTNFDSAATLVSSGSATALMGIQNPDGTTNNLVLDIHKYLDEDNSGTHKECVTDNVEEFKALAKFLRDNGRKGLVSESGASGAASCLKAFCSQNNFINANSDVFVGFVGWAAGSFDASYVMGLTPTKQNGKLVDNQLMMQSDPDPEAVRADADFPVARQHHGAWALDRPLPRQGDADGQRGDDPAADGGADGGLEVQHAADRFVHGDVHHVAHLGHDDHDATVQRDGGAARDAEPDLPAARAQPAGVGADALAQGAGAGWVVPSWGIGGYGWGDGDDSGKRPGVYGNAGRYAVIVGGLNLRFACGCRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4V2</accession>
    <name>A0ABR1X4V2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005379</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673312.1">
        <property type="nucleotide sequence ID" value="XM_066809694.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042754"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056693">
        <property type="entry name" value="DUF7791"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25053">
        <property type="entry name" value="DUF7791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="313"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7791" evidence="4">
        <location>
            <begin position="451"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8090418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="857" mass="95679" checksum="897172ADB37090A6" modified="2025-10-08" version="1">MDALSALSVAGTIITFVDFGGKLLSNTRKLYKSKDGALGSFVDIEVVTSDLIALLEGLKKRTPESHLPSGRQYHVLGSDEDDEALDKICVRCIALAEELAARLNRLKLATAPQDGKTQTGTGSPPKSASNPSKSPALLAHMVLGAEGSKKNERARAPAFRKWESFRKALEAVWSKREIEEMAAALRDLRDEMEFRILVSFRRSLHTVAGQQSDAAIQLEQSTRTIIDTFLNSRDSFADQIKVQTEKLVQIQDLLTTKHVDNTRRVEDVTGGQLDAIGSFESTLGGAGRPRRASEDRSERALAVEENLLPWHNLVAWLRHGDGIYWINGKLGSGKSTLMKYVYEHSKTRDELKSWAKGHPLEISGFFFWDRGDEDQSHIYMKQLAKRHPDETSQLVSDVVHKARGVFLWVKLVTRSLLGGLSDCNRISDLRKRVSHLPSHLEALYRHILDGVDPFYRTQMSQTFQIVCAAQNGSPGLVTLLNLSWADDEDGPRVEDAPIQPYTNDEIEERCEIMDARLKSVCAGLLETTRIKFSSLRPDRRVVYLHHTVSDWLAKPDVWKHITSITAGTGFSPNLALLKSRIMRLKTWNSAGDGILDLSLVVDALHYAREAERDLHTRDFTSYLQLRPLYLSTSSLSSSSGSSGIWYSFPEAGSEAGDNFRQGGQVYPEERGRRAFEESIDRPHWSRAIEVPGGRALDGRGTFFELARAFGLTHYVDMKYDAGHAAVEHEVSHWLLLQAFSGTCGSATANRPKDPNVEQVRRILASGVDPNLSFDGGLTPWQGAVFNAFWHLSRRPSPSDDDDPHALWREKAQAWAQILEAFLQHGSDPACPAVRRRQLPRFPRVTPTALVEAYSVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4Z1</accession>
    <name>A0ABR1X4Z1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription factor hoxa13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005436</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673369.1">
        <property type="nucleotide sequence ID" value="XM_066809751.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042811"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23242">
        <property type="entry name" value="TRANSCRIPTION FACTOR HOXA13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23242:SF9">
        <property type="entry name" value="TRANSCRIPTION FACTOR HOXA13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="675"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="409"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="628"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="688"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="715"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="742"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="762"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8090475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1198" mass="126431" checksum="E33746D71DB9F624" modified="2025-10-08" version="1">MQFTEQAKQTGSNGWLEGRSWNIGDNAKEGCLCLEEASFARQLVASSIHHGGKDKKTNGHTNGSLNGLSQANGKSITTRQRTPPVKRAAKKNGFLARIISITARLLTWYSIISILLRCPASIQDLTESSPKVCKPYFQLKEVPYYDTVNRTVVTPARTYAVKYGGPQLTKAQALGLAQWEKTVQPQLLKYQALALAQYDKNAAPHVAKVTDVVEPYFLVAKANALQTYNDVMLPAYVFVQPYALQGYDMASSFTVDTAVPTTLWAWNKTYIFLDGVVWPRVRNVYIKTVDPQVARIMERLGRHQDKRVKTFNDENESTKCHVSSSVKSAFVKPTASVSSTESSTATTKVAEATAKAKSAASSVEPEADPSASVEVNIDSDSSEQSKEDVRVAAAKTVAEDLELWQGKFTKAAEESAEEIEGRVQDLADRLIQEEAAVVGKSHLTKLDETVKTELSDLKKTLLGVLEKHRDAGAKTDASQLEEDVAAAVRASGLKIRDQAQAIRTWRQSYEEETETAVTAIAQEHIRILESIRDLALQKLGMKWAWMDGVTYKDWQKYHQLRARLDEWTDDLKVLVTTHPSLPKVQTAGTDIENEGMAVAAEAAQELGSLKQVAAWKALAGDYTDDFDASTMKLAAEAAQQKAAEALKEAADDAEEIVQSAAGKVKESVESVGEAISEGASSVVKPSQAAASGDGADAETSAVPPMESMASEPTEAASDLSSSKSASAGTNAAESVEPLPTEEVADVDGPEQVEESIVASPDYPSSSAGSATPSVKSAMFGAMAQSVPSRKPILDDYEDDAEPFLSNVKSSLPTDAAASVTAAAQAAYTSAIAQAADKYSSAMSAVSVQVSGTPKPAHEEMFSSVSQGYFDALATANSRLQNAATAASQGIYGTPTTKWMPDMPTMPNMPSVDWERVQSIAQKNLQDSVSWAGEQFENAKVVIGAAEPTPSTPSERAVKMLDQAKHNYYAGLGVAHARYDEFLSAASTAVSSMTATPTPTDIHGTASSVASVAGESASSVASVASEAAASAASAAGDSASSAGDSVAANWDFLVSQVSSQVYGAPTPTPWYENLYSAAGDYASQAGDYAASATGAAADSLSSANSVAGEYAGSATEAAAAQYSVVSSLVSELIVGKEPTVTESVFARLAGVYGAASATASSAMSEASVAAAAAASNVADTASAFTEGVKETVNHDRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7S7</accession>
    <name>A0ABR1X7S7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_001845</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ZNF598/HEL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673456.1">
        <property type="nucleotide sequence ID" value="XM_066806160.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039220"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16615">
        <property type="entry name" value="RING-HC_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057634">
        <property type="entry name" value="PAH_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041888">
        <property type="entry name" value="RING-HC_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056437">
        <property type="entry name" value="Znf-C2H2_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044288">
        <property type="entry name" value="ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938">
        <property type="entry name" value="ZINC FINGER PROTEIN 598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23202">
        <property type="entry name" value="PAH_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25447">
        <property type="entry name" value="RING_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23230">
        <property type="entry name" value="zf-C2H2_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="109"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="379"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="440"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="653"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="388"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="440"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="456"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="478"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="656"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="669"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="679"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="694"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00035113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8091484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="825" mass="88564" checksum="539976DD12B51E27" modified="2025-10-08" version="1">MSSGGAADTNGPSSAPARPRGDGQGRERGRGRGRGNQNQAGGRGGRSQRGRGRGGQGGQGGQGGAAQQQSAAKGAGDDSSAAPAQAKKVIGAAAPSGDADGDDVEAEVCFICASPVVHQSVAPCNHRTCHICSLRMRALYKNKECAHCRTASQYVIFTDDATKRYEDYSADAPDITSVDDNIGIRYAKEDIVGDTVLLLRYNCPDVDCDFAGLGWPDLHRHVRSAHNKKMCDLCTRNKKVFTHEHDLFTDKELEKHMRNGDDRPGAIDQTGFRGHPLCAFCGSRFYDDDKLYEHCRNKHERCFLCDRQDPRQPHYYMDYPALEKHFQKDHYLCSDRECQEKKFVVFASELDLKAHQLSEHGSTLSKDVRRDARLVDMAGFDFRQPYQQERRGGGDRGGDREGGRGGRGRRGRDPNAEPIPASSAQPLRRDELAFQRQMAIHSSQSVSTRTFGGQLSSSTAGPSTTSSRNAPAGQRNGASTSNNAAPAAEAVPTAGMEGLSVTDPNLTPEERARLVRHASVVERASNLLQNDASKMATFRAKISAYRQGSITPTALVESFFTLFSETSSTALGTLVREVADLFEDKDKAQRLRNAWNDWRAINEDYPTLPNLSGMHGATTQSSGWAAAASSSATAAASNMPTGRHTTRVLKLKNMTQQSQRSNSQQSNSWAASAGSTASRPPPTVSFPSLPPARTSTPKGSKGPKPTPASSSSSAATSASLWGPSSHSQPSSSSNNNNTIHRAPKPAASGPEFPALPAAPKPLTTIFGYGRGAVRRDVGGSRDTGFNWNGRSGGDAAGADAEVEEADATDAKGKKKKQKKVLVQWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7U6</accession>
    <name>A0ABR1X7U6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673504.1">
        <property type="nucleotide sequence ID" value="XM_066806208.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039268"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="468" mass="52453" checksum="4A4C914869ECA5DB" modified="2025-10-08" version="1">MSQDGMNLGPSAWSEDMSRQLAYVLASMTQRLDESANSSSFHPTPQPSLRKWLSHYLNDRSLPSPPAAFDLPEPPAPNSPFRDRLIESWDLYYPWLRIWQQKVRDAAADAHGRGLLGNETELMHRLKRRHPPLSDISKCTTTYRTGFGAERFTFTGIGSNPAEHAGNEDAMDREVVVDDSSSTLSDTTSDPNLGSKDVIDLRDSDSPESSHVNPRMFGAIRAVDYMAQYGEVGAQVYHWFNTALGRVSRPEPSELQVPSDEDERQLLSHAEIADVEFDTTTACTYPITLSEAIHRRFWVCRTRVGVFCLPCPCPEIVSPNPPGSKSGATHDLVPRNFYFDPLVGDQGLRHFKTKHSFHGKTTPGLLATRGRKVQASHSEVPSIAAHNFAISLWHSELDSQWDMITYLVPTNEEIQRRSTIGSLVSKSGKETSLTIKNSFRFRIKDGGDDTYVVLCCGPFREKPWMPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X924</accession>
    <name>A0ABR1X924_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Isochorismatase hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673852.1">
        <property type="nucleotide sequence ID" value="XM_066806556.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039616"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF9">
        <property type="entry name" value="FAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="4">
        <location>
            <begin position="58"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8091880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="179" mass="19430" checksum="E346E01EB087F6B3" modified="2025-10-08" version="1">MPPAFMAGFSGGTMRPDKSFGSEMGMVEDSPVPSSNGTTETTSNNNKNSTNMVDAGPMLMRDTWNARPWGPLGPMMDEGLAAGTDLLFHKNRLSGLWGPQTPFGLWLQENQITTIFFGGVNADQCVWSTLVDAHFKGYDTVYVDDLSATISPDYTTQMTRYNADGYGKKPAPDCPNAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X992</accession>
    <name>A0ABR1X992_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002383</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673994.1">
        <property type="nucleotide sequence ID" value="XM_066806698.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039758"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF252">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="319"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8092022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="355" mass="38990" checksum="40DB82987BBCDD88" modified="2025-10-08" version="1">MASITQIISWIVQDIYHGWSPLPLPPAGSFAGQTVCVVGGSTGLGLAAAEHCVNLGAAEVIITSRDNRRANVAKEHLERKAARAAAITTTAAAAESSPPKTECRVRAMILDMNRYSSVVAFANDLKQIRKGQGGIDFILLNAAVIQSRYLQSPEGWQEELQVNTLSNVLLTLLLLPWLRAERKNRSSPAHLAFTTSTASIATDVSKWEDWSTSGEGILNHWNKKENWPSGLSGGYPVSKALLMYADRELNKLVVGPDGKPWVIINSMEPGMVKTEIQRHVLENSPFLQFLAPIIIPAIFKTSENGARILIMGGLTTEEEHYARSRQPNGEETTEDRLGRDHRRPSQSRPGGQRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA58</accession>
    <name>A0ABR1XA58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674256.1">
        <property type="nucleotide sequence ID" value="XM_066804483.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037543"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="267" mass="30862" checksum="ADB78E61A046C598" modified="2025-10-08" version="1">MDIVNSTILQDVQTLFYKVTTTDIRQVAKDFSTDDNVSTLRDGSREVVVEFTIASKCIRLMQCFDIDLDEKKPFDKTRRYNDAEQRAHELSNEPPMATDVQQFLMARMVWENGGGLRGVGPKQQTEMEVNYKKSSKDFENLRTEAQESFWLHSTRAERDALRDAASNGDDQIDHIITVIKANWTRRWNNGRFDQDHFRHYLDDKIVAEQVWELVDADVFIVVDAKRRVVLANVESAAQLLFGADIVHELNRAIDMFSFFVPIPAPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAP1</accession>
    <name>A0ABR1XAP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000332</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674420.1">
        <property type="nucleotide sequence ID" value="XM_066804647.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037707"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045226">
        <property type="entry name" value="Dsc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025390">
        <property type="entry name" value="Dsc3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019413">
        <property type="entry name" value="Dsc3_ub-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049:SF1">
        <property type="entry name" value="DSC E3 UBIQUITIN LIGASE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN YOR223W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13373">
        <property type="entry name" value="Dsc3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10302">
        <property type="entry name" value="Dsc3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="30"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="335" mass="35616" checksum="09C7A6D670184107" modified="2025-10-08" version="1">MSSLKPPPLNSAALGPSPNLTPAPLSPQPLSLTIRFSASIPDLDLEIPHPAQTTVVSLKHLIRGRLAEPNSQRRLRFIQGGRILPDTAALSAVLRAPPPAPPSRYEEYESLVQRQGQGQKHPQPPPPPQRIYVNCSIGDSLTTSELESEAKAALSPPPTNLARGPPTPGGPNNATGTTTATNNNHSQPSPRGFDRLLNAGFTPAEVNQLRLQFRSIHSSRYTPDTLPSPDSFRRMEDSWIDDNGAAAMPTTASNTGGGSGGLDDEGGGGGNNAGLAGHLDALVWGVVTGFMWPLGSFGWLVRQHGIHSDRWKFMVCVGVFFSFLIGIVRSISGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBE4</accession>
    <name>A0ABR1XBE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CobW C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674757.1">
        <property type="nucleotide sequence ID" value="XM_066804984.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038044"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051927">
        <property type="entry name" value="Zn_Chap_cDPG_Synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603:SF1">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="315"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="534" mass="59702" checksum="15A0DCC05B055E51" modified="2025-10-08" version="1">MAQAKRKNGGQPEATAAGKKTKGSTTAILNKAVPAKPLPVTLLSGFLGSGKTTLLNHILKGDHGLRIAVIVNDIGAINVDAKLIKQSNHRLTKTEEKELVHLAELDQFNYIVIESSGISEPEQVAETFDEQFSETMRAIDQNADGVDQELDDDMRDVLRRIVDAGGLNKFAVLDTAVTVIDAFTIMDDFNTDQLIGDTRKDVVPDEDERTVSDLMVDQIEFANVIILNKMDMVSSKELTSVRSLVSRLNRRATVYETSLKRAEFDVKSILNTKTFDLESAKVRKTWLEDLHHMTMRQINGRNKITPKPETEEYNVRNFIYQRSRPFHPQRLWKLIYDKFIVQQQDDEEEQSSGGDDEDGVSSDIGSDEESDVTSGDDEEEEEELSPPSNQEILGTFFLAARPNYQGQWSQAGAMLALTGGDPWFCTLPFEEWTSGDAEIDAMIWHDIRGDGSDGGCWGDRRQEIVFIGEDLDVEGLQALLDACLLDDAEFATWEAIMKMAPLSDEGKTAALQKVFSDGFAGWAEYDNDEHDHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBH7</accession>
    <name>A0ABR1XBH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP citrate synthase</fullName>
            <ecNumber evidence="2">2.3.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_000730</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA</text>
            <dbReference type="Rhea" id="RHEA:21160"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.3.3.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674818.1">
        <property type="nucleotide sequence ID" value="XM_066805045.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038105"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032263">
        <property type="entry name" value="Citrate-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056749">
        <property type="entry name" value="Citrate_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF10">
        <property type="entry name" value="SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16114">
        <property type="entry name" value="Citrate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24948">
        <property type="entry name" value="Citrate_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-citrate synthase ATP-grasp" evidence="12">
        <location>
            <begin position="2"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-citrate synthase citrate-binding" evidence="11">
        <location>
            <begin position="284"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF24948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8094045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="471" mass="51334" checksum="69F2ADFCFF89FF09" modified="2025-10-08" version="1">MSAKSIFEADGKAILNYHLTRAPVIKPTPLPKPTTHNAPPRLASLYFPEDAEVSAVLDQAEVTYPWLLQADAKFVAKPDQLIKRRGKSGLLALNKPWPEAKAWIAERAGKSQKVEHVEGVLRQFLVEPFVPHPSDTEYYININSVREGDWILFTHEGGVDVGDVDAKAEKLLIPVDLSEYPSNEEIASTLLKKVPQGVHNVLVDFISRLYAVYVDCQFTYLEINPLVVIPNADATSAEVHFLDLAAKLDQTADFECGVKWAIARSPANLGIMAQSSAGDKISIDAEAYIAELDAKTGASLKLTVLNGNGRIWTLVAGGGASVVYADAIASAGFADELANYGEYSGAPTESQTYHYARTVLDLMLRAPMDPKGKVLFIGGGIANFTNVASTFKGVIRALRDYAKQLNEHNVQIWVRRAGPNYQEGLKNMKAATQELGLTAHIFGPEMHVSGIVPLALVPGKWEEGKVQEFQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCH5</accession>
    <name>A0ABR1XCH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">5'-3' exoribonuclease</fullName>
            <ecNumber evidence="13">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_001058</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Possesses 5'-&gt;3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.</text>
    </comment>
    <comment type="function">
        <text evidence="11">Possesses 5'-&gt;3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II. Essential for vegetative cell growth and chromosome segregation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with RAI1; the interaction is direct, stabilizes RAT1 protein structure and may stimulate its exoribonuclease activity. The interaction also stimulates RAI1 pyrophosphohydrolase activity, probably by recruiting it to mRNA substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="13"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675146.1">
        <property type="nucleotide sequence ID" value="XM_066805373.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038433"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017151">
        <property type="entry name" value="Xrn2/3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF41">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037239">
        <property type="entry name" value="Exonuclease_Xrn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 13" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0806">Transcription termination</keyword>
    <keyword evidence="14" id="KW-0862">Zinc</keyword>
    <keyword evidence="14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="16">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="411"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="513"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="825"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="515"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="832"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="881"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR037239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8094373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="998" mass="112402" checksum="4E9C84CB8847FDD5" modified="2025-10-08" version="1">MGIPAAFRWLSNKYPKIISPVIEDKPIVMEDGTVIPVDTTRPNPNGEEFDNLYLDMNGIVHPCSHPEDRPAPEDEEEMMLEIFKYTDRVVNMVRPKKLLMIAIDGVAPRAKMNQQRSRRFRSAQEAQEKAADKEEHYKMLKKQNGGVLPPETLEAMAKKAFDSNSITPGTPFMDILAGSLRYWCAYKLNTDPGWANMKVIISDASIPGEGEHKIMNFVRSQRASPEHDPNTRHVIYGLDADLIMLALATHEPHFRVLREDVFAQEGKVRTCKICGQPGHEAAQCRGEAKKKDDEKDKEMPLKPFIWLHVPVLREYLAVELSVPGLPFRWDLERAIDDWVFMCFFVGNDFLPHLPALEIRENSIDTLSAIWRDNLPIMGGYMTKDGDVDLEKAQFILNGLAKQEDAIFKRRREGEERREANAKRRRLNDERNGRFNNQNRNGNAGLPASLSNTMTHDMVINRNAVPDANAANKSAAAVLKSQIQGLMPKEAAQDGANNQDSSSALGKRKAEMIENDSASTPGSEAQAETPTPAKPDPSEDTVKLWEDGYADRYYEQKFHVDPKDIEFRHSVARAYVEGLAWVLKYYFQGCASWEWYYPYHYAPFAQDFVDIVKTKIDFKKGRTSKPFEQLLSVQPAASKHVLPEVFHDLMTDPESDIIDFYPEEFEIDLNGKKMAWQGVALLPFIDMPRLLAAAEKKYPLLSPEDRARNEPGKDVLLLSEANQELYDDVISNFYSKKQGAPTCKLDPRASQGLSGVIEKMPEYLPHSDLKYPLERKAFPDIDDDRSLTVYYEMPKSSHTHKSMLLRGAQLPTPALNNSDIEELKGKMRNSGRSHGGAPLGRGGYGGNRGRMNYGPDSRGGRQDRPRYNNNNGHHQQHGSNPFPAPPPGWVPPPGLIPPPRDKLALALDCRLRRRVRTAATTSSRTSSRTNSLQVSTVIRVATKHPHRPRRGMPDITSMEEVAAAANDHMIMAEAEAEVAAIEVDGATGDELAEWHRGTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCQ8</accession>
    <name>A0ABR1XCQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">T-complex protein 1 subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_001134</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675222.1">
        <property type="nucleotide sequence ID" value="XM_066805449.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038509"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03337">
        <property type="entry name" value="TCP1_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012719">
        <property type="entry name" value="Chap_CCT_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02344">
        <property type="entry name" value="chap_CCT_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8094449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="499" mass="54784" checksum="3159FAAA04565C08" modified="2025-10-08" version="1">MQAPVVVMNTQSGERQTGRKAQMSNIAAAKTVADIIRSCLGPKAMLKMLLDPMGGIVLTNDGHAILREIEVSHPAAKSMIELSRTQDEEVGDGTTTVIVLAGEILAQSLPQLERNIHPVVIISAFKRALKDALEIIDEISPPVTWETNGKREVDIKRYARVEKVPGGEIEDSCVLDGVMLNKDITHPNMRRKIENPRIVLLDCPLEYKKGESQTQIEVSKEEDWNRILQIEEEQIKAMCESILAVKPDIVITEKGVSDLAQHYFMKANVTAIRRVRKTDNNRIARATGATIVNRAEDLQESDVGTQCGLFEIEKIGDEYFTFLTKCKSPKACTILLRGPSKDILNEIERNLQDAMGVARNVMFQPRLSPGGGATEMAVSVRLNQLAKGIEGVQQWPYKAVADALEVIPRTLIQNSGASPVRVLTELRAKHAEGNCTWGINGEAGTLADMKEYGIWEPEAIKLQSIKTAIEAACLLLRVDDICSAKKAQQMGAGMGGGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD15</accession>
    <name>A0ABR1XD15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675318.1">
        <property type="nucleotide sequence ID" value="XM_066805545.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038605"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="118" mass="13461" checksum="AE088C02A84165FE" modified="2025-10-08" version="1">MNTLLRLARLLAGYHFDEGCSKIICEDGTAPQACDVHVHKYAVRQRQETVRADFQVRRDPNWGANLNWSALPVQTGQSREYKRHAIMEERLGNGDAILRCRRYSFGGTVSYTGRYPCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD64</accession>
    <name>A0ABR1XD64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675414.1">
        <property type="nucleotide sequence ID" value="XM_066805641.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038701"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42041">
        <property type="entry name" value="DNA ENDONUCLEASE ACTIVATOR CTP1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42041:SF1">
        <property type="entry name" value="DNA ENDONUCLEASE ACTIVATOR CTP1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="348"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="479"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="619"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="648"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="536"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="584"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="688" mass="77777" checksum="2D4CD8AC94CDBF59" modified="2025-10-08" version="1">MEPSSSQPGSPGVAPLQLMSPDRVNQQTSPTRSSHHRDSSIHDKIQQFNSMSQQMSSASYSKQLERKTADAALKRAMLGREEAESEMRRYRDEARALRRHVEEGRERERRVGERLETVMENYGRAKETYAHTQALWEKEIRKARKETFKSQSNIVKLQEELKSAKSAAKSTEEVLQRERERSQAREQEAFEARYQIVGVQEQLEQALQQIKAVEQERDAFKTLAKNEEVARIAAEGRLPLPPPEAADDEFSSPKKARPSLNTADIVSSAASEAEIEDLTRLWQWEKQRADRTQDHLEFLQTECQFRCCPCASKSSRSSFRRSLTSSARKPRPEPMPIVDAADLVILGQKPKGQERLPTPTPTEDDTVIHEVQDDDEVEDARVSQAREESERPTKPRTSKEPRRSTIFVPSEGIFRTLSQHEIEEMEAVRENTAEPPPAPVPAPAPEEANRNPVYYSRTPSVEPPAFALLAQERKERTSLLSLLNAPRQSDPHSRAMNIPTARGYTPDAYEDPQQPAYGQSTGNSSYHASSSSEQARPSEYKRSSEYKRSSEHKRSSENARLSDTKRSREHARAVEQAHAESRLRAQQASSAFHTTTTTTSVPIREGDKNPREYMNRAMNSRERAPSFDVHNPALTPTMTREEALAQIRERRGRARSAAQGAVTPRKQMVSGERRDVSAPAGRAVKGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD73</accession>
    <name>A0ABR1XD73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675387.1">
        <property type="nucleotide sequence ID" value="XM_066805614.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038674"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="32175" checksum="1277E11CA9C04852" modified="2025-10-08" version="1">MMTFVAVSIFLLALAAISIYALVEASRLSLPVSLSLAVLTLLLPFTAWASLFGAPMFRRLSSFKNGGGGAGGIGDLMRHPLVPFALQVLQGIASVVMATLWSQGLMGSGQAVDCNMQSTWKRLWMAHDGRSIETIQNAFGCCGFNSVRDMAWPSPGGNVGLCRELTHRETSCAVPWRGTLRRLSGFEFGVALGCAAIQFFYLARTLLRIFQAARETMSRRSSRHNTAALEQGPDASLVPRSTGSGHNNNNNNTNSYRTMGHTYEARDADPEVLDDDAEEDVHRDTTRLLRNNNTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE79</accession>
    <name>A0ABR1XE79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001612</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675700.1">
        <property type="nucleotide sequence ID" value="XM_066805927.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038987"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="13084" checksum="4E501F44F243A2F9" modified="2025-10-08" version="1">MEMTSTSSASASAASERRRVLLTGFRMESCGYAPEGASAGRRSTRKIQRDVPELIETCEDADLDALGAVQWQVQENRARAGMRAMERTAFRYLRRHAWNLTARGRWWRGWVWCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQG4</accession>
    <name>A0ABR1UQG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphatidylcholine-hydrolyzing phospholipase C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_015373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660572.1">
        <property type="nucleotide sequence ID" value="XM_066819687.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052747"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22893">
        <property type="entry name" value="PlcA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049756">
        <property type="entry name" value="PlcA-like_dom"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8061152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="935" mass="103894" checksum="7DB730F9D1DFC093" modified="2025-10-08" version="1">MGDITDVTGPDEASLEARIRESGYLMPPEFPESEKATFAINSFVAPYKPNRSTLSSMEAPHDDLLVTVSGVKLTFGHIVALAGDFYTNREDRKNYFPIADTDQFGRDKGSRSKKTIEQRFDCAVTSLIEDQDGYLKRVQALLDQEHDTVDHALQEDESVARAYHTHATYDNCHIPTDKEFFKAAPTPDLEKMLSFYAWLAYTNIDHFGEDAVTAYSVGHTRALEIARAASKEPSMEKKAEQLRRAYIYEAFAAHYLTDLFSAGHLRSPRRELHTQHNLEMAAAGLLDVPMWDVQNRFMHDDDSATGIMVRNKNGDQWIEYGDKQFFEPQACVNRARSMHCLDLSVQEVYKIGYSSSQVIGSWRDNQNWFAAIKYIPQPMTAVAPQAWLKDWGGYDMHNPAPLWLSPGGGADQEDGWTIRKDLDNHSDFGARVSGSLRNTGSTIGTIWKPAATKECQQIKDARFRADDQFPLQSTIKGLLSGDPSGQAIHYMRKSVWGKSACVLGFSGAEKPDQKCDITMQVTTYASRDLRVSGGGGPVSLDLSKSWAMLPIMSSYPTVLLSDLPSRRCVNMTRFTQGHFIQEPENEYVEQDLIALAQIKGQGVEIGLLSVLDIETPIRHHLDGLSHGAAYGFVKTFRGANSSTDTLLLARAIPKAGHMLVDLVRVRFDQLGNPGMEDSSFQFKCNHIDQPASALVGDVLGRGYDQVVILASDAETAYISVYGSNSKEDVAFSPLGTQKYTLDGDSALTRPILTALVPTSTSNGGLDVLDISRHQSGPSSDVLAGEARPFLPKCKEVTVSDPLASSNAAQYFSIKWMPVRYKPDPDKEAERRGILEIFSWYGVLGARLFGPGKRGWDYDLLGQLPYLGQTSIGAGLGCYGDWGHGFVTWAKEDEWIDMNMFVPSDKNDTTVGSWGMTWDDLDRPHVRGWEVEKRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQM6</accession>
    <name>A0ABR1UQM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_015447</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660646.1">
        <property type="nucleotide sequence ID" value="XM_066819761.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052821"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF163">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_8G05510)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="37"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="246"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="297"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8061226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="344" mass="38006" checksum="D658126A34646B1B" modified="2025-10-08" version="1">MAEIQVDPIIEAVYGPPPPGLDLNDDNYFIYNIVAIVFFIVAVLSVILRAYVRMTRGAGLAMDDYTIVGAIQMVYAEPWIYATAVTVTRVSILLLYHRLFDTNTTSNMVYIWQTRFAIGLTAAYPFVMYIGVCIDVLNFYLAFGVLNLINDVVILALPIPTIAKLHMDWKKKLSIMGIMLLGAFSCVSSLIRIFYLARLASSKDVTWWFGPGMGWSCIEPSTAIITACLPTLAPLFRKNKPSTGGSSNNYYRSADGGTKATRRGGDTCAAERGQQEWDKIDDDDEIELTGAQRHVRASSYSPSGMMDNDMTHPDGGITVETQVDVSSSHSQVSSGQVWQDKSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU58</accession>
    <name>A0ABR1UU58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661061.1">
        <property type="nucleotide sequence ID" value="XM_066818873.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051933"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11578">
        <property type="entry name" value="DUF3237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="195" mass="21051" checksum="9D4954C1BA91390B" modified="2025-10-08" version="1">MPSVAEQDKAAVAGLESFPTTVPAMRIKCSLSGQFPCGDIHTGSTLVGVPLGFGTLESVGDFEPKLDFKLSSGHDWFRIDADKRHGRLSVSAIATDAEGRSVRLIADGVTELNEFTMPLIMGDPEAKTNPFGFGAYTEPSPNTVEQMRFEAGHEAYKPLEGMMFACSQRFAKDEETGVPMAEIRVSRIVPGSGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUX9</accession>
    <name>A0ABR1UUX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="1">FBP aldolase</shortName>
            <ecNumber evidence="1">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661329.1">
        <property type="nucleotide sequence ID" value="XM_066819141.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052201"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050246">
        <property type="entry name" value="Class_II_FBP_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304:SF0">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="290" mass="31488" checksum="E1FD55C1B4799BF4" modified="2025-10-08" version="1">MEWKKDNRTYKILSDAEKGGYGVVAPIAYNIECILAFIRAAEAKRAPLIIQVFPWAITYSDGLLVHAAAQAARAALVPVAIHLDHAQDAALIRHAAEKLPFDSIMVDMSHYEMAENLAKTKELVAFCNTHKICTEAEPGRIEGGEDGIADTADLEGALTTPEQVDDFVATGIDFLAPAFGNVHGEYGARGPVLEYDRLAAIRAKLSASKDTDVRIVLHGTNDFPEDVMKRCIQGGCSKINVNKLVLDDYLAYMKAQAATASLTTFMEEGTKAIQKLMEWQMDVTGSAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV85</accession>
    <name>A0ABR1UV85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014684</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661186.1">
        <property type="nucleotide sequence ID" value="XM_066818998.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052058"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="70"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1066"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1175" mass="132756" checksum="B82A5B21EFB2F7EC" modified="2025-10-08" version="1">MRLFWWHDFHDRRLSASQLSPEDQLFHPGLWAKVKAHDFLVMYRWENLAPVFTKAQYDYNLHEKGILPFITKDANVKEGAFSWVHKVTVHPEHTEHADKEVAIKEIRVNRGGDDSRTDEAWEREARALASINQVDHPNIIRCLAAIRRQNSRYFMFPWATGDSLRDFWLERPEQSPNATLINETLGQLIGLADALGKLHDFEGKVDPSAFHPDEDDNITMEGGQDSIRHGDLKPENLLRFLEPESTLGTLKIGDMGLAKKHVLLTVKRKCITTTRYGTIQYQPPEAELTTNGGLSRLYDTWSMGCIIFEFIIWLLYGNDALDRFYQDLQGKARNACPYYELPPQGSGDGPTVHPVVQGWISHLQQYDPECREESAISDLLKLVKEKLLVVDLPPSRGRTHRAGSGEPTIAIIQPPNSGILGLGHRATAEGLLEGLTAIADKVRQNPAYLLTGADRDNIHLPPLPRDQPTFLSPGNGARKRKAQDITSDQDVKLLGGPFPPVPIRLKDWSYPVDNDFALVVSQAIGRDKLMPPGSSLPKLCIRCLRLDFWAGGFSFEVSPSQLHQDSPKCDFCCMLLRVCTQFDMNREAKVSFIREQSTLRIVGGPPQPVLTFMRSPGIFQPARSYTAWVPTASACRESSGNGDHPALAARLRLHTCQLPWPRIHGRSHQADRDWKRRKLTLRLIETAEKPPQDGRYIALSHPWGDKTKHIPFCTWRTDVRNDGHDVETFKQAIPFDKMPATFQHAVTVALSLGIRYIWIDSLCIIQGPDGDFNEEASRMEDVFSGAYCVLAASRATGMHDGFLGERAGRDFVTFAQTPAEKKFYVCEPIDDFSQDVLESPLNKRGWVLQERALARRSVYFTKTQMYFECGEGIRYVLRNADPWPAVSIISNLSAFLGDPRFPQKAVEGRRGMKIAYFQDLYKQYSRLEFTRMEDRAVAILGLENRLRKAYRTDGGFGIFDDGADGGLFHRSLLWRRGIEQEKPDMRSIIFPLERRRGTAEVPKWSWMAYEGPIDYLLEPPFDEEMEWETRDIRPPWSRHQHQTSQRQQPGSLLSAERRSATAPLDHHGKASVPTLAVVARDFNVVGFRGGEVQVLYDADRSASDGGGKAQCVVVARTKSGESRQAKRHYVLIVVAELKSSPAGLGTGLKYHRVGVGYMLGKFIAWDKPASEGLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVE8</accession>
    <name>A0ABR1UVE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661508.1">
        <property type="nucleotide sequence ID" value="XM_066819320.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052380"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="169" mass="17894" checksum="B29D0360EC957E82" modified="2025-10-08" version="1">MGNGNQRQMNDPPVDVMAHIQAGASSEDDARYRNLALAYLAFEPSQEVVGAAPPSSAVTNTPAHVPNSTGYIGPTHVGSMSTPPAAQGSAPAQLSVPSVGSRGPFASQPVLSTVEVQQTPRPFSFSQGDTSTNQKPRLLQSNEAIRQYHDTGACELGQQHRLYRGHAYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWS4</accession>
    <name>A0ABR1UWS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">6-hydroxy-D-nicotine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661109.1">
        <property type="nucleotide sequence ID" value="XM_066818921.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051981"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="133" mass="14984" checksum="A1B5A1CA4F943E72" modified="2025-10-08" version="1">MTLLHAGFPARDSRCHTRHVSRYRPHETSPRVIPRNHPAADLPRGRRHRCGNSLGVEPAAQTWLATAVSWLRPEDDAIAHAAGDEIRSEFEAAAASAQSRLRYTFMNDASWSPDVIASYSKTNVRRLRMVQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2P7</accession>
    <name>A0ABR1V2P7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661966.1">
        <property type="nucleotide sequence ID" value="XM_066816274.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049334"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046853122" evidence="1">
        <location>
            <begin position="16"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="78" mass="8220" checksum="FCC70FB2A23E98B4" modified="2025-10-08" version="1">MPWLALGWHWLGGWAARRGGHPLAFASHSVDLEPHDAAVLHGLVSALGALRDPSVRDLLSSASSLFPSMFAPGLNGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2Z9</accession>
    <name>A0ABR1V2Z9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Myosin I myo5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662305.1">
        <property type="nucleotide sequence ID" value="XM_066816613.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049673"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039719">
        <property type="entry name" value="FBXO28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13252">
        <property type="entry name" value="F-BOX ONLY PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13252:SF9">
        <property type="entry name" value="F-BOX ONLY PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="4"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="620" mass="69339" checksum="0A4072CCE97B90C3" modified="2025-10-08" version="1">MAGLSALESLPHEIILEILSFLETKDIIHLQRCSRRLLKLSRDNVFWRTRCLLTSSFLEGINLRRGARFPDVIEGALNEDAALQDHDGPDTERSPPPLDFPWASRRAREKEIQKITANWDPSFPGETISWYDEYIHRNSPIAVSWFERPQLRDGGLKDHIEVKGVAVYQHGDEEVFAVSPLDDGSVCLWDIKGTRPGKKKGSILQQSKAGLLRMGSSKSPYLSPDCVSVDNARGRAFFAVQGHVVEVDLGTLQVVGDQPYEWTITTMSSAQPRVPLTIGTLHGIHLHDSRYGRYVEQTRQERIDDFDRYNAPRRLSLLLFSDPLPPYAPLPHSNPLSILHLEQPGNKQAVSDDIFVAGRFSNILNYDRRMFPSIKGSLHSGARLCSLTSLPYPFSSVDSELRRKGELSMEQVEKIKETTGGRTLVACGEYNTKGSLEIYGLGPPLPGQEPHGVSLNSVMKNRQTASKSKLLSVINHGTCLVVSDGSGYLKWVERDGFTEVRRQYIGPSERVVGHTSLFNEMPGSGEIARKLLSTQSRQASDDKSNDDDILLWTGEKLGLVDFSSKQGFTADDFEEGDTRTPEEVAAEQEKQHYEERMRQALERDADGVRLFKVLGAGIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3K2</accession>
    <name>A0ABR1V3K2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">OHCU decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012489</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662495.1">
        <property type="nucleotide sequence ID" value="XM_066816803.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049863"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3330.10">
        <property type="entry name" value="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018020">
        <property type="entry name" value="OHCU_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036778">
        <property type="entry name" value="OHCU_decarboxylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987:SF1">
        <property type="entry name" value="OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09349">
        <property type="entry name" value="OHCU_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158694">
        <property type="entry name" value="UraD-Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase" evidence="3">
        <location>
            <begin position="101"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="295" mass="31765" checksum="C814ABCC15FDC581" modified="2025-10-08" version="1">MPQFTPMELKLRIKRIPNHNELGVGFTTKERSNVETPPYVELQPRRTLSEFMEASSASSSSTAAPAPSATPDAAPAPAPAPSNAAPPPPSLPPIDSLSTAPIKTQIAVLDTLFERSTELHTLVLPTLRRKRTPTADSSAGGPGPATSEADHESPLSSYTSLIRHVGSLLASLASQSASFGTTPSPQQQKLHGILGSHPRLGAKKVESAQSQAEQAQLNQGGAEEAEKLKALNDEYEQRFPGLRYVVFVNGRSRPVVMEDMRRRIDRGDPKEEEQEAIKAMVDIALDRAKKLNAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V490</accession>
    <name>A0ABR1V490_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF2254 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661890.1">
        <property type="nucleotide sequence ID" value="XM_066816198.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049258"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37576">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37576:SF2">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="16126" checksum="29FA186F16097213" modified="2025-10-08" version="1">MHSQPENSGTEWTPGLWRNVPWTALFSLVGFVLLCVGLAVILRTSDGREVETWPYHSQTIPVSVLLALTVSIANLCLSIALSKGYEISWWLKAVKGADLRRLQFDLDVQHHLSAITGRNTRLDSFAISAILSLAVSILSGPPDPEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5I0</accession>
    <name>A0ABR1V5I0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Esterase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662007.1">
        <property type="nucleotide sequence ID" value="XM_066816315.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049375"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="48441" checksum="81F569CCBD45EF88" modified="2025-10-08" version="1">MFNILTTERKPTPDQNFSTHAAMRRCPALRGSSAISTRICRPHLQCRLYASKAPATEQNSISSDQAKSSSNSARRRSPPPPPAAHNDEDSNSLFHDWDQAFQIDQDAKTIETAAGSLPLSPVMDPSFWAKREQYTKRKPKHTPSKPQSTFERQFAANAFAQALATPVRYDSVIRFRLPSFFLQDFHLVTHPETGQPWWVPRSLALENSNHGENKNNKGEEGVSSTAAGNDANKKKPSREKLLGPNAYGPARKDVLAAMSQDKSGFYGQSRMLFGPSSSQYKIFGNKAVWRQDMDEFVLGLMRQHVEQDLLYLSRLCVEQGRYYIAKCFGWGDVQYKHKGAVLWFGDDSPAEDGKPAQNSPGPFATYEFADKEGAKTAVAVHNMPMLLGEETAARVRKEAGALQDGSIFMLAGRRSTDLQLKLWKLQGYLSDYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V921</accession>
    <name>A0ABR1V921_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lysine-specific metallo-endopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663554.1">
        <property type="nucleotide sequence ID" value="XM_066817862.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050922"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045244963" description="Lysine-specific metallo-endopeptidase domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="480" mass="53039" checksum="64FAB5BC1D517E29" modified="2025-10-08" version="1">MFFRNYVLPALVPLFILAILLPVFSQVSDGSGYSTLLIDESCDGTQTETIRQAHRDAADLAFTALDIDRNETSAIYKYSINFDSTAAIDYFGSPSENFAYREHILRTLTRASKINAGWSGGGGSSNNHPIIKVTCNDPKGRCGTAASTAYTYNGLDQKHPLINYCPGFFQTLRSHSDAWHRMRDGPAPPDAWHNVRNLRSQASTALHELLHINSSWPSNVCAGGCADTLQGLDGGRQMVWTYRAGLAKLLARRDVAAAARTADNYVYYAMARWMEVKDAAQYPPYPVAWSPVQSRQWNEDREAGEPGAPLPGTTDLEEMDVRDDERPDVYKPVYSGDAYPVWYAPILETMESASGNVTVDVQQPPPANKSATYSDPDPDTIKCSSSDQSPSYFDCVRTFQSDLYRELSYVETCAINISFLEDWDDRCNATLGDVTDHARGIFRKCNDGQLGPDGRCEGQVAFTVPHCPADIQIVRATVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAY8</accession>
    <name>A0ABR1VAY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carnosine N-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013845</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnosine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663851.1">
        <property type="nucleotide sequence ID" value="XM_066818159.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051219"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF6">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="399" mass="45131" checksum="EF88C183C08EFA1B" modified="2025-10-08" version="1">MADGQTTKDEGDDTQWNGVEDTVEDPEELRVIFQALDSFSQYAKTAHLNCTHLRRRAFYAMPQAQWQMLAKPPFSYLETLDRTDAAIDSNAGLARAIVQYGLASLGVYNPSAGDAEENQMMIPKEWVGVAKSNDMDKARSTIRQFYRDWSAEGAAERNVCNDRVFRALDAEKVRQPDRTEPWKVLVPGAGLGRLVFDLCHKGYLSEGNEISYHSLLASSYILNHVEQAGQHTIHPWIHTFSNHRNREQQFQSYKIPDIQPQETLSQAQGIGAMQMTLTTPWLLYFFLDTAPNLIRYLEVIRHCLKPGGVLINVGPLLWHWENNVASNSGYDGEDDDSSGRGIAEPGSFEFTADEVVALVKEMGFTIEKYEDNIRAPYVQDEQSMLQTVYSAIHFVARKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGT7</accession>
    <name>A0ABR1VGT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664170.1">
        <property type="nucleotide sequence ID" value="XM_066814880.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047940"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045438096" description="Amidohydrolase 3 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase 3" evidence="2">
        <location>
            <begin position="72"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="685" mass="73909" checksum="B3DF4A0FBAE9526D" modified="2025-10-08" version="1">MLHKPRLILGLGLASIAGATAPEPADLVFRNGSIYTLDAASSAAAALAVKGGYISTIGQDADIELSIGVDTKVIDLQGRMVMPGLIDSHMHVLQGGLGLLKCDMNYQPVDINQLLTHIQGCIDGDGKKADDDWVEVVNLDYPSLVTKSGGVSKRELDKLQTERPIVIRSSDYHTVLLNSRALELSNITAATPDPPGGKIERLPGGQDPSGVLQDAARGLVNLPPPTEAVRLEACRAALRLLRQAGITTFQEAAAGPDAFTLFGQLRASGELTARAYFDYSIEPSASVDGVEGLVANTVAAIKSMNDNSTIEPKPTMKWQAIKGFLDGVITYPARTAAVVDPYWNPVNGSQTDGGEWAPDPSTMNEPYWSQEILNATLEGLFLAGIDAQLHVDGDLAVRYGLNAAQAFMEKHPDRKGDFRLGLAHEELLHQDDWARFAELGIDPIMSFQWAQLSSFYIPSTFATLGDYRRGNLQAHRRIEEAGRPIVYGSDWPIDPLDEFLALKVAVTRSGDPTNPNSPASFGAPYDGIFPGDPISRESALRAITINGARFLRADASIGSLEVGKLADLVVLEKNYFEVPEEEIGRQRVLLTLVGARSCSRPTMRSRSSESRRRFRILASRLTAANSTRGRLVASIGGVYPRRECLLSLDFGDAANASTNTMTSFEGSTLDELGSLAHLLAFKILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIB2</accession>
    <name>A0ABR1VIB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664783.1">
        <property type="nucleotide sequence ID" value="XM_066815493.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048553"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="39191" checksum="91EFE2FA34069658" modified="2025-10-08" version="1">MELTPIRIPGKRRKKGEPPPSKKAKRDVAHKPAMKKHKSKPSKPKGSYLERELPLEILERIFWASETANLAKASPRIGHMLSGPATRRATFLNAFGPTWDVWFGCLKSGPGVKSYHGWQEDSSRFGGSPEFQSSLLEYSWVDVSFIMECWDLWVKRYGRDRFFQHEKLWGSPNTPNRLDSSDPDGLKGSTPPSGMAYFLHDYDSFVAKSAHNMTYLGDHTSLIEVHCDTEIPEKLLMGPWDEAAVQKLFWLVRAGARLSATQTWEATLEGYHTALSEETEPATGRINIPVIRLLLKLGGTDHWPKNVLSKELGDLFERAGRVPDEARLKYQAVYYMIASKWSAESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ14</accession>
    <name>A0ABR1VJ14_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665041.1">
        <property type="nucleotide sequence ID" value="XM_066815751.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048811"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="741" mass="83016" checksum="871202D9BE03155E" modified="2025-10-08" version="1">MGGLHWPQECTAQAFAWLDHCIEHNISFPQTVVEHVIANVDHPRTFTQYTQVCQHIASYAKRQIDRQTSQDIRSKLEGTRKVVMENLLVDGTSIVPNLTGNTPMAVLIAGIKASLAKPNVAGAAEMKKVNEAGGSAKDATMHDDDDETEVQSFSEDSSESEYGSKPKRKAAAAGPSRNFRKKRQQSAAAQLPPPKKPRLAKQNTRNLEVDVEDELSVEGPINEGFTRRPQRHVLPAKAPQPRKFSAQSIVQPQDRPRPATSTVPKPYRAPQAEDSPEPGSPLRVAENAFPHTPPRQTHIQDLHQQEEMAPSFHPGITIQETPHAQQDSESQQRSSQASTEIAPETEVGQSQAHGLPEQDAGTETGQSQAQSHGGLPAQGESALLRENIRLWKMFTKEKNEKLALLESNKLFRHMLSSPANHPSLVRTRHQELQDRFKSQEKMNCDVGELERGLPQLSKGSLVKRFEDLQFHIQDACDPFHLTGLKETLNVSGNDTLGDKKINLLFKTAFGWGLNAWELRDDEDCHLFRALVTAHVFLFVFESDFPSNFTGHDDSAMLREFRKIIFEQNGAYSLHIKERVALQSYLEDRYYWMMPDKKPFQNVVQTKAEALALDVAELFAPLNTPTSVVANHLTTLYERALRLKADLVLSNQSYIARFVPSKDPIDLTVVDIENDVSDRVVEPTKVKQCFFPIIYFKPNPEIDAVTTELSQCMVKYTNFAILDSRFGKPGDATMLYKGIVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJF2</accession>
    <name>A0ABR1VJF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665177.1">
        <property type="nucleotide sequence ID" value="XM_066815887.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048947"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF82">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="65"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="679" mass="75788" checksum="300D4F6A091B1770" modified="2025-10-08" version="1">MDGENESSSGTDAIVASSAIYATLPEADAIRLLELYPASQHGMPLIGRIVVTTLRSCRDDLVDRYTALSYVWGNPVPTDSLTVDDGHGDLGMTSNLATALRDIRHASVSLTLWVDAICINQGDLTERARQVRIMGEIYATAGSTIIYLGSPAPGLEVLFETVQAKANARLGIKTTVETEIPQTLAHAIEQFCSYDWFGRSWVFQELVLSNDPRVQCGRMRARWTEILQIVTETALGAQEGYLATSSRLPRAMDETRGSSNPKHRTMANLIRARAGSYATDPRDYFFSLMGLMSDQGKVGAYFQVDYRQAVRDVYVAAATYALGAMGLPNLLGSRFDPLWSSVPTPTSPLRAALPSWVPDWSIQTPWTPAWAKAEEERLEGSASSSFLPWGSSPMVFRGRLTLPVIQWQWREQRKHGIPPDLDRIEEISAILVRGSEYPIAEFEKLHVGFLELRSAIQPGNVYYLRDGWVRPLGAVVLDQFPHDFSLLVPERDGMEQDPRLREWYPERSQDAYNDHSLPQGRPTCRLALLALGHLHVVPADTAVGDFVFDTIDLGQRAGRKFVPHDGDWACCVVGRPLRPRPGDCDDDDYEKEKEDAEIAQHMAKVWGEKLQELRDQVSHDGVTSLSGLEVHELLHPRDINVHADQFAQVQHFRLVGFSQAQPEYNMRTVKMARGVAVIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VK08</accession>
    <name>A0ABR1VK08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665035.1">
        <property type="nucleotide sequence ID" value="XM_066815745.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048805"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="71" mass="7548" checksum="B4FD7D3D288CD317" modified="2025-10-08" version="1">MNSQIFSQAAKAAARQTAARRAFTSSTKSAPADYGRLFQQARRTGIVYVPGLAIVLGWPFAAAKMVDTVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKH5</accession>
    <name>A0ABR1VKH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAGA-associated factor 29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665200.1">
        <property type="nucleotide sequence ID" value="XM_066815910.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048970"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20393">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037802">
        <property type="entry name" value="SGF29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010750">
        <property type="entry name" value="SGF29_tudor-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047288">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539:SF0">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07039">
        <property type="entry name" value="SGF29_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51518">
        <property type="entry name" value="SGF29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGF29 C-terminal" evidence="2">
        <location>
            <begin position="132"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="265" mass="28321" checksum="4D2D98A0586C56A7" modified="2025-10-08" version="1">MDRLLRSGVKVTDATAAEIKQIIEQLKILKAVKEANEMETTNQLTSSSRSATQRAKESATASSSVYDFDGAGDSPVPSPNPSASRRSAGGAGSSKGDRDSVPPKLDRSTPAAKAGSVEPQGAASVAASAARSKVLFSKGDHVAFKPKGANNEPTDWILGYVQEVRGEGKSRRYKVIDADPDEAGNRSEFRTSASNMIAISKEKDPLPPLDTGKVVLALYPNTTTFYKAEVMGMTEDGNVNLKFEGEESSNTMQSVTRHYVLEYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKL1</accession>
    <name>A0ABR1VKL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664644.1">
        <property type="nucleotide sequence ID" value="XM_066815354.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048414"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="8"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="23101" checksum="4854ED60DF33A4A7" modified="2025-10-08" version="1">MRVALRSSPITSAAKNFATKPIRQPQRAAFSTSRQYNARNQVYDTVRNPAAFQTYVQLSSSSRTPLLTLWTTSWCGTCRVVKPLLQEMVESGVGEAEGGVGFVEVEVDAPDVMAENLGFTYMINSIPTLLSFDGGEAMTQTKVVDGKRLRDRAWLEEWIRTEARRHGGRGGGGGGACALLGACLGAGRARSVCSCPETKHTALKKKQKIQMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKR2</accession>
    <name>A0ABR1VKR2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily subfamily IIA hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664704.1">
        <property type="nucleotide sequence ID" value="XM_066815414.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048474"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006353">
        <property type="entry name" value="HAD-SF_hydro_IIA_CECR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01456">
        <property type="entry name" value="CECR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF57">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="430" mass="47063" checksum="0CF29F2015029AB7" modified="2025-10-08" version="1">MSASLLRSSFSAGLRPRSLLNSIVPSCKAVGAAQTARRLGSSGVSQFRHNSLSALGQCGTSSRSYSIDYKQKDSVQAPPFAFAFDIDGVLLHVTKPIPGATETLRYLQKHQIPFILLTNGGGKHEKDRVADLSSKLNVELSTENFVQSHTPFQELVHGPKGLKDKNVLITGSDAAKSRKIAETYGFETVITPADILMAHPTIWPFEPLMKELYAATARPLPSPNPKIDAMFVFNDPRDWALDIQIISDLLMSQNGVLGTYSPKNGKPDLPNAGWQTDGQPTLYFSNADLVWAAQYHLPRFGQGAFQAAIAGIWKHVTGGIELQRTVIGKPYKETYEYAERVLTNHRAQMLGTEVKKLEPLRSVYMIGDNPESDIRGANDFASPVGTAWSSVLVRTGVYTDARGEPAHPPAMVVDDVAAAVEWALKREGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLL4</accession>
    <name>A0ABR1VLL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_011323</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664928.1">
        <property type="nucleotide sequence ID" value="XM_066815638.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048698"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14127">
        <property type="entry name" value="STKc_CK1_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="13"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="305"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="391"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8071120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="449" mass="50146" checksum="66A824F34EB0071C" modified="2025-10-08" version="1">MASSSSNVVGVHYRVGKKIGEGSFGVIFEGTNLLNNQQVAIKFEPRKSDAPQLRDEYRTYKILVGCPGIPNVYYFGQEGLHNILVIDLLGPSLEDLFDHCNRRFTIKTVVMVAKQMLSRVQTIHEKNLIYRDIKPDNFLIGRPGTKAANVIHVVDFGMAKQYRDPKTKQHIPYRERKSLSGTARYMSINTHLGREQSRRDDLEALGHVFMYFLRGGLPWQGLKAATNKQKYEKIGEKKQTTPIKDLCEGFPEEFSKYLTYVRNLGFEDTPDYDYLRDLFTQALKNTGEVEDGEYDWMKVSKDSGKGWDGMHNKPSGYHNPNQRPGPSQMELHGNSRKGLSNPGLTIERLNAAQPPPPSPAKATDKRRPNAPGALNPQRTSGVGGLRDMATPTGSTQAQFQNSSQNLPPRMSAPQTNISGGAQAMPSNGQPTQPQPTGFQKFMKVLCCGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VMC3</accession>
    <name>A0ABR1VMC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011277</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664882.1">
        <property type="nucleotide sequence ID" value="XM_066815592.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048652"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="LigT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="290" mass="33060" checksum="5015339525B22365" modified="2025-10-08" version="1">MGNILESTDIKNKLEDLSGVVVKPGENPYNALIEACEDDPEQTQALYSAHRVRRNDQQKEKFLSPELNELIIDPWLLRLETPEIEPGFKDLRNCMTFWGRPPVHVLELAEKIQSKLKAVAPNIWLMPTYRMHITTLELAFSRTPEEIDAIVRSLRPAIPSVASYTYHHRARLVKPMISYDLSAFAVSFLPACGEPVVSPPPVAPGITEGVQQGDQYTYHHLRRDMWNLAKDAGMEIDSRYIVPSAHITLGRYLTDKDHATPEQRKKWIEAIEERSTDGWRQKFGTPPRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VMZ3</accession>
    <name>A0ABR1VMZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665031.1">
        <property type="nucleotide sequence ID" value="XM_066815741.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048801"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10216">
        <property type="entry name" value="ASKHA_NBD_Arp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="360" mass="39717" checksum="4CF346962FA3A8BE" modified="2025-10-08" version="1">MAEPLHNAPIVLDNGSGTIRAGYAGTDLPACYFPSFVGRPKHLRVLAGALEGDVFIGQKAATELRGLLKIRYPLEHGIVTDWDDMEKIWEYVYSEGLNAMSEEHPVLLTEPPLNPRANRDTAAQILFETFNVPALYTSIQAVLSLYASGRTTGCVLDSGDGVSHAVPVYEGFAIPSSMRRIDVAGRDVTEYMQTLLRKSGYIFPHLGREGGGPADQGMDSGKAVDYVLPDGHRLKVGPERFRAPEILFDPEIIGLEYPGVQQIVTDAINRTDLDLRKSLFSNIVLSGGSTLTKGFGDRLLNEVKKLAVKDMRIKIFAPPERKYSTWIGGSILAGLSTFRKMWVSIDDWHENPDIIHTKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT18</accession>
    <name>A0ABR1VT18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009059</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665336.1">
        <property type="nucleotide sequence ID" value="XM_066813374.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046434"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014612">
        <property type="entry name" value="Pop7/Rpp20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020241">
        <property type="entry name" value="RNase_P/MRP_Pop7_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28256">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28256:SF1">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12328">
        <property type="entry name" value="Rpp20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="205" mass="21913" checksum="6A5D3F0D02C01F1C" modified="2025-10-08" version="1">MTEDAGELPTAAQIQLPGDDNKLATPATTHTKLPPIPKGATVHRNLIGPRQPSTSKAVRLYITPKTPFRSITTRVRKHLDKILRTASTANPHQSATAQIAKRSFGLDRRVNALQQTAGSGIGLEGGREVVVLGTGRAIEKVLAVAAFFQNQKDCEVRLRTASVPAVDEVLAAAGGDGDGDENNSGEREEARARMVSCLQVHIRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTJ3</accession>
    <name>A0ABR1VTJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4470 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665518.1">
        <property type="nucleotide sequence ID" value="XM_066813556.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046616"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4470" evidence="2">
        <location>
            <begin position="120"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="582" mass="65090" checksum="0EE087F968E65DBE" modified="2025-10-08" version="1">MGNYMGAAIFCEKVLKLLQANPDPDLEQKVRVRMGKSYMLSRRPTQAAKAVGTNLDDSEDKRQIEQSIQAVEASDQLFPDPAKHRSQLLDRLSRLKFALQDEPEYYSVGHDDPEPEFNQEMANSNQDDYSFLFAGIGDARNLFATLITIGSLTASNPSLMSKKFHFALLDIKPAVFARDFLMFRLLLDTRQESSARASETLVALSYLYTASTMPGWAYSRVQMAIKDLLRELQVEDSPVITKFYVSNADRVLIGSHLQNWQKEPSDWYSTSEFLTRTQINLLAGKTKRTLGQGPESDSGAPAGCQAGSPDVVEYEDLGVMLPPTHLIKEHEDRLVELLKEYRKKRTPGNKRKLDHYFQEQWKPNMTLVDFEWESKRGGNPDPLLDFTPHKTASLLWGNLPPGTLGKKVSGVLPHLEGFFGCVAKALGKFPDQTTFEIVIGDMVNYFESAEQGLLRSEEHSKSSAASNFPDTFDRIHMSNIPDYVGGAMATFLYALPVLRPKKTSAVTSNVLRNTRVWATHDSFLVDSLLLAGRAKIENTFSTSLVPECSQVEKALDGSLVGGMGAIMVFSMKWMRQSSKALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTN6</accession>
    <name>A0ABR1VTN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665560.1">
        <property type="nucleotide sequence ID" value="XM_066813598.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046658"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016833">
        <property type="entry name" value="Put_Na-Bile_cotransptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640:SF5">
        <property type="entry name" value="SODIUM_BILE ACID COTRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 10 MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13593">
        <property type="entry name" value="SBF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="453" mass="49572" checksum="7494969A8510C744" modified="2025-10-08" version="1">MSNLRDPIRKVHFQDIDTCPGQETPTTSRQYSEIALYLILHETSQNGYREGKCDSDSSRAPAPDCVIPLLDTNQRPMVSDSPCRARDFLFPGAGPGSAAKGQDAHHTVRDNSRHILHQRPDHADRRSRSQHTAMAVSRLHPAHGLLLHVAHDARARGGHRQQPSTLGLFAAERLGNTGLSADCVSEDVPILVVGVEELQLTADEYRFSINTLMARKAKGNATLTLTESVIGNAVGPFLSSLLVLGYTSISMWYTEVLPKTDGGLGELLRRVFLQFGLTLILPLAVGQLVQSFFPRVVGKVMHDYQAIRLGSLSLLVLLWSGYDSAFASHAFADVEKTQILGVVVICLSLFVLWMLVTIAASVTFLDREDTIAAVFCIPTKSPALGIPLATILFAGMSAEDTAKVYIPLIIFQFVQTCLSNLATIPLRRWRAKLVYETDSDTASDAVELAECPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU26</accession>
    <name>A0ABR1VU26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">F-box protein pof7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009421</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665698.1">
        <property type="nucleotide sequence ID" value="XM_066813736.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046796"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045464">
        <property type="entry name" value="Hrt3/FBXO9_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874:SF9">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19270">
        <property type="entry name" value="FBO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="228"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="543" mass="61057" checksum="C2287B571C718183" modified="2025-10-08" version="1">MESELENFREQWRAEVARSRNTAATSGTQQQQQQRPQKAQAASSSSSRVPPSRKHEPSANPRIASKIASHQHQEDDDDLTRGQAFDEPAGPVIAPNTLAAFEKGSGELEKEPETALEFYERAVDKESAGKLGDSLHLYRRAFRLDNHVEKAYRDKHFPGRWGKQPQQQAPTPDTAAAINPSNAPATVPNTAHHSLDGPPLSLPDLIASFAGLSIQPASPEVEGMPAPPSPLSALPEEILVHILRDVAILDIADFVRLSQVCKRFAFLVATEDRIWRRVSLGEEFGFGAMVYHFQRGISWEDLSRDGPTTLEEAENLLSLEELRRHQKAEAEATTLELVRSSLYASSWQNMWRRRPRIRFNGCYISTVNYIRQGHSTGNQITWNSPVHIVTYYRYLRFFRDGTVISLLTTADPADVVHNLTKELVRQHENKAMAHLPTAVMSEARKGRWRLSCPALDKDPDADTDLAEVEGDLFVETESAVGPKYEYRMDLALKSAGKGARNNKLIWKGFWSYNRLTDDWGAFELKNDKAYYFSRVKSYGFGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV17</accession>
    <name>A0ABR1VV17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribonucleotide reductase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009754</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DIF1/spd1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666031.1">
        <property type="nucleotide sequence ID" value="XM_066814069.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047129"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013900">
        <property type="entry name" value="RNR_inhibitor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28081:SF1">
        <property type="entry name" value="DAMAGE-REGULATED IMPORT FACILITATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28081">
        <property type="entry name" value="DAMAGE-REGULATED IMPORT FACILITATOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08591">
        <property type="entry name" value="RNR_inhib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="30061" checksum="554D1947EB62DD83" modified="2025-10-08" version="1">MSVPRTKRQFAGASSDPSQRQITSFFNSSGVVSSTPASLNSAGASTPRSFVAASNTDQANLLSVGMRVRKAVPEGYKTGTYSAFSLWDEADNEMAGAGAGDTGRSRANAVSTPRELLPFCGINKVGGLGAQPSTETFSFNATTPVHQTTVRSADAMDSSDELPGLTMSQDSTSSNDSVSSVVTGARTRKRFFVEDEDDKPEMPGRLNIVGWHDDDAVSPRSVAPAGWGNGRVMAVPRKGRSRGKLAGMSGRAAAMGQENVMVMGNDFDEAPFLDRTWEVEMSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV64</accession>
    <name>A0ABR1VV64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009770</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666047.1">
        <property type="nucleotide sequence ID" value="XM_066814085.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047145"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08022">
        <property type="entry name" value="M28_PSMA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02121">
        <property type="entry name" value="PA_GCPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.40">
        <property type="entry name" value="Transferrin receptor-like, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007365">
        <property type="entry name" value="TFR-like_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036757">
        <property type="entry name" value="TFR-like_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF46">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04253">
        <property type="entry name" value="TFR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47672">
        <property type="entry name" value="Transferrin receptor-like dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="185"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="6">
        <location>
            <begin position="380"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Transferrin receptor-like dimerisation" evidence="5">
        <location>
            <begin position="659"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="785" mass="86683" checksum="99C5CFF5BB0F6A54" modified="2025-10-08" version="1">MEKMASSERTPLIASVTIGSVPRRYPHNTLRRFCTIILGASLIGLFTTFLFTVVFAPHDEAPPHSSPHPPGHRHHMKGLSFDQLKEILLETPSGEKASEWSKYYTAGPHLAGRNLSQAEWTRDRWNEWGVKSEIVAYDTYINYPLAIDWLCWRTTLEEEVLDEDPTSSLPNRIPTFHGYSASGNVTAPFVYVNYGTYQDFEDLVKANITLAGHIALARYGGIFRGLKVKRAQELGMIGCVIFTDPGDDGEVTDENGYETYPNGPARHPSSVQRGSVQFLSVAPGDPTTPGYPSKPGVPRKPVDGAIPSIPSLPISYAEAVPILKAINGHGPKATEFNQYWTKNTGLKYKGVQYNVGPSPKDVVLNLVNDQDYTITPQWDVIGIINGTIPDEVIVVGNHRDAWIAGGAGDPNSGSAVLNEAIRSFGKALDKGWKPLRTIVFASWDGEEYGLIGSTEWVEEYLPWLSATNVAYVNLDVGVRGPYFSASAAPMLSKLIYDVTSMVQSPNQTVKGQTVRDTWDGHISTMGSGSDFTAFQDYAGIPSLDFGFGGYGKDSPIYQYHSNYDSYHWMSEFGDPKFAYHKTMAQILGLTVGKLADTPVVTLNATEYATALKGYVEKIEAKLASVDAQSEPTTDEDIVEFRARSIGSEPTGNVQDFKFSLSRLYESVAELTSASVKLDTKATKLAKEAGEHLPWWRLIKKLRLFHAIRSTNTKYKKIERAFLFPGGLDGRPWFKHVVFAPGIWTGYSGAVFPGLTESIDSKDFINALRWVDIIDHCIKTATKTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVH3</accession>
    <name>A0ABR1VVH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665767.1">
        <property type="nucleotide sequence ID" value="XM_066813805.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046865"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="241" mass="27333" checksum="93D0D493ED450CA4" modified="2025-10-08" version="1">MSESTTPPPLSTVKESWSQEEMAAREAMNEVPSYEGDGELPMRKSISRQSSRQHSRQQSRQPSPDKSLKKSPTKSAKSSTKSPIKSQVQVKPQQQEDDEEEEEEEEEAPVTQTRISVDRRQTRTPRARAAPEPASLGATIAQHAWAHCPFDWDDFEARYQKALGEADEKEKAILEEFDQLVKYFNVWASASSSHDNERAVKRLQTRTRFVHLSEQKLNQKKEHLSEVVKAFQSALALLSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVH9</accession>
    <name>A0ABR1VVH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666188.1">
        <property type="nucleotide sequence ID" value="XM_066814226.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047286"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="195" mass="20779" checksum="76EE2B8D95B14B41" modified="2025-10-08" version="1">MSQQSPKDQPSSYGRPYVDYYPMPSIPPPRAGFTIREPHGSEAFTAKWTTTAAWKDADGGDGYPQPEKSSAAEEEGAVDKSTGGDMEHGAKSDEKTTNKEPSAAKTDPTVDVTGKEETAMLTYVAMCGREAGILFELSDSDLEDDDETYADSSKDPDTSSGPEGETAATNTVAVLKESESRVVQKGPVCVPPKNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVN0</accession>
    <name>A0ABR1VVN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009961</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666238.1">
        <property type="nucleotide sequence ID" value="XM_066814276.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047336"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF224">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="89"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="488" mass="51625" checksum="FDEED53A18C44E25" modified="2025-10-08" version="1">MASIGADSSLTMAELEKVQTPRKSHHQDISPSSIVTIPGQITESEKKAEKEADNAGDPPNGDGPGNSSVESSDVEDGGEDEAPDGGAKAWLMILGAWCCSFCSYGWVNSVGIFQQYYENGPLSDYTPSQIAWIPSLQIFFLSFLGPVIGRLNDTYGPRVLVAVGSFLHVFGLMMASLSTEYYQILLSQGVCSAIGVSAVFLPALACVSGWFAKRRGLAFGLLSTGSSLGGVVFPLIISNLLRTVGYGWTLRICAFMILALLLVANAFVRARHTSNTAANRARGGGMTRVQMLSPFRERAFQILLFGQFLIPYGLYAPITYLPSSAVGAGMSESLSQYLVTFYNAASLVGRASSGYLSDKAGRFNVFCGACFVASLLVLAMWIPGSTDAVIVAFAVLFGLSSGAYISLMAALVSSISPLDELGYRNGLCFLASSIGGLTTSPIAGAILESPVGGWVGLKAFSGVMMFLGTAVTLAVRFQKTGLKLWVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVR4</accession>
    <name>A0ABR1VVR4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666280.1">
        <property type="nucleotide sequence ID" value="XM_066814318.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047378"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="83" mass="9539" checksum="98A674BB9434CADD" modified="2025-10-08" version="1">MTTTGARGGTALRRQPAVFARHLEHCVDVLRQHLVCHADLEAFVVNWRVGQEKPYADFAVRKTCVDFEHLLEWSKRHKDPSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVU3</accession>
    <name>A0ABR1VVU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lytic polysaccharide monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666309.1">
        <property type="nucleotide sequence ID" value="XM_066814347.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047407"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF2">
        <property type="entry name" value="LYTIC POLYSACCHARIDE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046581942" description="Lytic polysaccharide monooxygenase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="39534" checksum="0D67651403D630C2" modified="2025-10-08" version="1">MYTATSKTLVAAALALLGTPHATLAHMIMKNPPPFGGAGLDNSPLTTKDYPCKVKGDPATFFKREKVTTVAVGEKQELSFTGNAVHGGGSCQLAVTKDLVPTASSHWQVILSIEGGCPSKDGVDASTYEWSIPDAVAPGDYVFQWSWISKLAGQPEFYMNCAALTVTGGKKKRDDDGGYEHERHNNETLAGTELFARAGDLPDLFVANLEGINKCVTKLNSDPKFPDPGPNVIRPGTKTDYAQVSGDCSPGGSGSGSGGSASAPASSAAAASSQAPPAGVTPSGFMTSIASAASSSAPPAAETPSPAATGSSGGSGSSSSPPPSGGETGACTEEGIFNCIGGSAYQRCASGKWTALEQMPGGTKCAEGKSANLWARGEAMMMRRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWA2</accession>
    <name>A0ABR1VWA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666458.1">
        <property type="nucleotide sequence ID" value="XM_066814496.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047556"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="22902" checksum="05210781CA41CF2E" modified="2025-10-08" version="1">MAPHWQTTDSFYELGQNSNTRPAGFRAVKNVWYVRARAHVTQYRRFYTIIGILSVVCIITFTLLGILLPPALRRQAENSGDNSPTATQTGTATASPTSTGKPSPTDAGGKCDPASFIDNVKMANVYVPDAPIQIDYPTANDAQECCEACWTSTEDHCNGWSYISNICAFTYDYPGSHKDDQCPKGHPKVTISKDGNKGDMGGYGPCAFQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWJ5</accession>
    <name>A0ABR1VWJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphatidylinositol-glycan biosynthesis class S protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_010262</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666539.1">
        <property type="nucleotide sequence ID" value="XM_066814577.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047637"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019540">
        <property type="entry name" value="PtdIno-glycan_biosynth_class_S"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21072">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21072:SF13">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10510">
        <property type="entry name" value="PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8075599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="533" mass="57932" checksum="09F9553E5D24CE11" modified="2025-10-08" version="1">MSADIINDGDSKPASAEATVSLPATGIATVERKEPPPEKDADTRRRTWIVISFWLIAVFIGLPIWWNTTTIYRANLPLTQMTDWADGKACEPVFPLRIALDVGSLPEQEAQNLLRLTQHALDDLNDFSGHHLRLQLAQAPAETITPVRDDSNVALTIRLAPGDAAHTASSSLHPHLPILDVQYPPNSLPTANSPSSGLATYIATQLGSTFAEEQNIISYLLETSSITSEHKPKGISQEVVDTVSKRMTRSLKYSQTYHLTFSLFTNGPVPSSWDIEAAIDEYLKPVLDMLKPIHDFTIDTQVQLYAAPGVQSQVLGKEDLSSFINAAEWPLSPSIGGAPTVNFIVYIGNQTIGVPSETSPGETSQSWMIPQWGSVYLLAPPAEATHVSSETLKQPILTFTSHLLTLLARIRSADLLLRASSSLGSLARLTLALPSISIPSNVADGVVKTIHHLELACASLGGAKSLEHARIAEAEAERAFFEKSMVGQLYFPDEHKVAVYLPLLGPIGVPLVMGLLNEIKTWKNKRSQKLKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWL3</accession>
    <name>A0ABR1VWL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Quinate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_010286</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666563.1">
        <property type="nucleotide sequence ID" value="XM_066814601.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047661"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF34">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0672">Quinate metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="25"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8075623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="538" mass="60043" checksum="8F654066CC0DFE95" modified="2025-10-08" version="1">MVGLLKLKEDRPTPKAVYNWRVYTCAAIASFASCTIGYDSAFIGGTLALPSFVDEFNFASMDKDTKALLQANIVSLYQAGAFFGSLFAYVTCHFLGRRKSLFVFSAVFVLGAGLMLGASAARGLGLILGGRVLAGFGVGGMSNIVPIYCSELAPPAVRGRIVGIYELGWQLGGLVGFWINYGVNTTMQPSHRQWLIPFAVQLIPGGLLAVGALWLRESPRWLFSKGRHDQAMDNLCWIRNLPRDDVYIVEEVNYIDEDLERYKREVGVGFWKPFAALKQRKVQWRFFLGGMLFFWQNGSGINAINYYSPTVFNSIGITGTNAALLTTGIFGVVKTITTIVWLLCLIDYLGRRKLLLGGAVGGSLCMWFIGAYIKIADTANRPVGSALDGGGIAAIFFFYLWTVFYTPSWNGTPWVLNSEMFDQNTRALGQASAAANNWFWNFIVSRFTPQMFLKMGYGVYFFFASLMILSVVFTYFLVPETKAIPLEHMDRLFAIRPVRKANDDIMEELRLADEEFRHAVEGVDLSERKEKVEMKETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX28</accession>
    <name>A0ABR1VX28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666750.1">
        <property type="nucleotide sequence ID" value="XM_066814788.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047848"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.70">
        <property type="entry name" value="TT1751-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035923">
        <property type="entry name" value="TT1751-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103247">
        <property type="entry name" value="TT1751-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="219" mass="23828" checksum="9B4E509218B14065" modified="2025-10-08" version="1">MEDRYRQYASSLTAPTGHCTIPCRRSFAETKAALGAAVPLLDRTYHRHLDAGDLVAAGEALRELPTLNRFGAQPRDFGPILRATAAAGTTTSQGDETGGINISSSNNPHPANTTTIREALQYEIGNPHKAAQMVRLRSQTALYAPIRVALLRGCLVSSSTGEVVSDRVWFEYDRPSHTMGSTGIKEVDEIAKGLDEALRGVLFRVAGLEMEDERFESKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXL8</accession>
    <name>A0ABR1VXL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009292</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665569.1">
        <property type="nucleotide sequence ID" value="XM_066813607.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046667"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004688">
        <property type="entry name" value="Ni/Co_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611:SF0">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0533">Nickel</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="398"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8074629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="435" mass="47375" checksum="9B9E765564DBD6CA" modified="2025-10-08" version="1">MPCWRLLPRRMDGLKGLPPAVTRVISLLVLANVLVWVGVAVVLKFYPAMISPAVLSYTLGLRHALDADHISAIDLMTRRLIASGQRPVTVGTFFSLGHSTIVIITCIIVAATSGALRDRFDNFQYVGSIVGTSVSAAFLILLCLGNGWVLYRLVSRLRQVLREPDPHHPEEGDEDEDRAAMNLQLEGAGFMANVFRKLFRIVDRPWKMYPLGVLFGLGFDTSSEIAILGIASIHGAQGVSLWVILIFPLLFTAGMCLLDTTDGALMMALYTSKAFARDTVAILYYSIVLTGITVMVSAFIGIVQVLSLVQNVAEPEGEFWDGLSAISDNFEIIGGSICGLFLVVGLGSVVLYKPWRRRMDRRRGARAQQVVSDPEYDDGNGFRDHVHDDEEGVITSELLETLDSPVEAAPPPAGDSKKGPAARVSERPGSPSLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYD4</accession>
    <name>A0ABR1VYD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">40S ribosomal protein S4-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665869.1">
        <property type="nucleotide sequence ID" value="XM_066813907.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046967"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06087">
        <property type="entry name" value="KOW_RPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000876">
        <property type="entry name" value="Ribosomal_eS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032277">
        <property type="entry name" value="Ribosomal_eS4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041982">
        <property type="entry name" value="Ribosomal_eS4_KOW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16121">
        <property type="entry name" value="40S_S4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Small ribosomal subunit protein eS4 C-terminal" evidence="2">
        <location>
            <begin position="31"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="81" mass="8979" checksum="A500C84BF5F768A4" modified="2025-10-08" version="1">MVTGGRNMGRVGVITHRERHDGGFNIVHIKDAIDNTFATRESNVFVIGSEKPWISLPKGKGVKLSIAEERDRRRANTLAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7N9</accession>
    <name>A0ABR1W7N9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldehyde reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007240</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666897.1">
        <property type="nucleotide sequence ID" value="XM_066811555.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044615"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="4">
        <location>
            <begin position="16"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="34377" checksum="09A84C4F22B22A0B" modified="2025-10-08" version="1">MVFSPSFDRLTEGDTILITGVSGLLGSATAKEALQQGFRVRGITRDPSKLLELQSAFDQDFGDRFQVCGMDDLTKAESYAPHHLQGVSGVLHIANDASCDINKTVAATVGLMREAAKIPSVKAFTLTSSRAAAFDPPPPGERLLVSSDTFLHDAVYRARSAPADGYLAYQASKVESEKAAWDVYRKEGLGSKYAFNTILPDWVNGAPVNPRPGFYSTYTGMTEFYSGSYGPTSTFYFFTHPPSTCVALRDVAALHVISLAAGEVDRERLFATQGTWCAADVVQAITKVDVAWTPRRSTPRRHPCPAATSWSRTSGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8F8</accession>
    <name>A0ABR1W8F8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007581</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667238.1">
        <property type="nucleotide sequence ID" value="XM_066811896.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044956"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF285">
        <property type="entry name" value="RETINOL DEHYDROGENASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="346"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="400" mass="44760" checksum="E7D5D325556351E8" modified="2025-10-08" version="1">MLELLGYLFHDGYPAWLPDPWLLLTIVVVALVIYLTKTYSNGMSNPIDGKMHGKVVMITGGTSGIGAAVTRGLAERGAQIVLLTRLPPSDTFLADYIGELRKKTGNEMIYAEQVDLTDLYSVRKFATKWVDNAPPRRLDQIILCAATLTPPVASGRSRNKALRRHGCPALRAQPIDRDVRVIIPTCASYISSPFLGEELDEKKWTPSKAYARSKLALMVFGQSYQKHLDAYKRPDGVPMNARVTFVDPGLSRSPGFLRWVTRGTFWGLALFMATYPLHWLLIKDSERGAQAILYAAMEPSLGRGYGGKLIKECMEVDFARKDVKDEAVAKKLWESTDKLIEKTEAEMAAVRVLQKKQKEMEEEERQKAEKVEEIEALVGSIKKGQEAAKAKSRRRNKKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBX9</accession>
    <name>A0ABR1WBX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxin-14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668506.1">
        <property type="nucleotide sequence ID" value="XM_066813164.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046224"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8081031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="28163" checksum="94C6CABE4E2A1C8E" modified="2025-10-08" version="1">MEYQPTSTPSYPPQPSRPGPVPLANPAATAPTLYATAPGAAGGGSASAYYTAATGPIGMYSEPNAVQQLPPRISSGDRSIKSARTTSSSSYSVNDPNAVDAMARARAQQGLVLDELQTLRRSLAVVIKEAEAHRWRKWVLGGMLASIIPLVRRIFRRPSKDSNKKGEDTITTTNTSKLDTAQTGSSSSSSNALMNATEYAFSKSRALIARIRASVRGSGWFLGGFAAVSFFVLSVLYVFENEVSLRVAKTVSKRLKRLAAKCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCI1</accession>
    <name>A0ABR1WCI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009037</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668694.1">
        <property type="nucleotide sequence ID" value="XM_066813352.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046412"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="9"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8081219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="52747" checksum="668EEC800BF12030" modified="2025-10-08" version="1">MGLATTVLSSLFLAIGGFLFGYDSGIITSTIALDTFRAYFSAPSETVTGGIVSAFQGGAILGTMFNMLFANRLGRRKTIFVGALVSVLGSSLQAGAVNMTMLIIGRFVGGVAVGQLTSTIPMYASELSEAKHRGMLSGLLQLMLSWGFFVAQWLGYGCSFVSTQLSWRFPLAFQNIPGLVLISGIFFLQESPRWLLEKDRADDARRSLQRLRRGLDQHLIDLEFREIRDVIVADRELGNVTWKSIVTKPTWRKRLLLGGINVINYYGPSIYKILGISTQQSLLVIGISGALSIVYCSIGLLLLDRVGRIKPLLVSAAGLGAALLVNAVQAQYFLDGESSGNRNAHQLRSMVAMNFVFSLFYTPLGIISWVYPAEIFPVEARALGNAVTTFTNWAVNLIFAQFTPAALAAIGFRYFYVFFALNLVAFLCYWFFYPETKGRTLEQMDELFGDQMVPHALQDETAAAIALGKQGLATAEVYEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDG0</accession>
    <name>A0ABR1WDG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribokinase</fullName>
            <shortName evidence="9">RK</shortName>
            <ecNumber evidence="9">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_008359</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-ribose + ATP = D-ribose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668016.1">
        <property type="nucleotide sequence ID" value="XM_066812674.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045734"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="Ribokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584:SF166">
        <property type="entry name" value="RIBOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 9" id="KW-0630">Potassium</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="10">
        <location>
            <begin position="10"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="18"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="37"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="234"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="267"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8080541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="320" mass="32938" checksum="48E600F961EBBDB1" modified="2025-10-08" version="1">MAATSTQVPLITVLGSLNIDLVSYTLTSTSFSVSPGGKGANQAVACAKLSRTRASVQDGNETAHVRMLGAVGADTYGDILVKNLAAHGVDAAGVSVRPDPAKTGVALIVVDEPTGENRIILSPEANHSLQPADFATLPGPKPDLLIMQLEIPHPTVLAALRAAREAGVDVLFNPAPATPDLAEEAYEGLAHLLVNETEAATLGGVKEADIEDEAGLAAVAQKFQARGVETVIITLGGRGVFYRSADGAQQGLVPAEKAKVVDTTAAGDTFAGSYALEFVTAKAQGTPFDIGAAVRKANKAAAKTVEKLGAQDSIPWRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WET8</accession>
    <name>A0ABR1WET8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">COP9 signalosome complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008416</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M67A family. CSN6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668073.1">
        <property type="nucleotide sequence ID" value="XM_066812731.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045791"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08063">
        <property type="entry name" value="MPN_CSN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033859">
        <property type="entry name" value="MPN_CSN6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF8">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="MPN" evidence="4">
        <location>
            <begin position="18"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="239"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="401"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="46869" checksum="5DE55B66ED137C25" modified="2025-10-08" version="1">MENPLISTQKSTDSGLQAVLHPLVLLTISDYITRHTLREQKGPIVGALMGQQNGREITIEHAFECATTVKDGHVVLQPDWFATRLDQSRCSAKANAQKAKSILTARSPVRTVHKAPQLDLVGWYTVTPKTGPMPSVLPIHNWLLSEHNESSLLLAFHSEEAVDHSAGSKLPLTIYESNLEVDEPKPDHGEDKEMRDGDAPLKLKFRELPYSVETGEAEMVSMDFVVRGAGNATAVETKEQKKPQMVAVDTDTKGKRRIVSPDNAEDETATAPEEHVLSPEDEELIMSLTGKANAIKMLQSRIQLLVTYLQQLPPSYTGGNTAAAATQPSQGTQPHSVPSHTILRSIQALANRLALIVPSATGAFEQEMLSERNDVQLMSLLNEVMGSSIDARNIAKKHSAVEAAKGNSRKNMHDVGGSSNYSMAGPGDLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMJ9</accession>
    <name>A0ABR1WMJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669211.1">
        <property type="nucleotide sequence ID" value="XM_066810288.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043348"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790:SF4">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="423" mass="48922" checksum="086400016D5A6D40" modified="2025-10-08" version="1">MATISESTRIDEPVAVRLIRSGAPVDAQVNSQLVSKLPREVRDQIWQLAFQVYQDFNSPYPLNKVHVRPGQAARLRINLALLLTCRAIYLESYLMPFRENTVEIYAGDEQDVPTEEEPLRWAHFAPPYYEPMSRMRSWQFANLTKVSIRFQQNQLEDSSHLRRIGRMMGANERHESRLVGVKLNPHWRQLPVVWGEKFDEVPWPEGAPALEKNLMKAHCVGQKITQLTIRLGMSDWWSWTDAPADGHSLRLDQCLRIEPMHTGTGDVDDAGAMLQGYLARKNGEEPDFGLCAHGKSHCWGNALCDIFPDLERFELELEAHEKKAPQLATVVECGKLWKFPQEAGYEMRWDREEELPYIWKGPMNQYIRCPWMDRRGTKAVGKDKPEHTAWTGPTSSETFDNGIRYVVQRLVYRRRKVQEEPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNY1</accession>
    <name>A0ABR1WNY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4-coumarate-CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006453</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669691.1">
        <property type="nucleotide sequence ID" value="XM_066810768.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043828"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="44"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="294"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="421"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="519" mass="56362" checksum="A906D9781009A488" modified="2025-10-08" version="1">MSRIYAHRDPYFAELEMPAVDLLTLLFDSEHSLAKDASVVHVEAANPANKLTKAELRSFIEQVAHGLRTNYGIGANGPSEDVVTVVGFGQILMPAVFYGVIAAGGVFSAASPSSTVSELARQISQAKSGLVICGSEHIDVATKAAAHLHSVAGQVEAITDSRLPWNRVTDRQALRDSLIVILWSSGTTGLPKGVMLSHQNLVAETIITSVYNRKWAMEQIEKGVAIPPLTHLPTSHIAGLWGYFVGALYAGGTVYWMRKYNWPDLLRYAKEFKITARRTRSSGAEAGQPRQQQMLGQTWGLSETTGAVTAVPAGESDDTGSIGSILPTIQLRLVDEDFRDVEPGREGELVIKGPVVTRGYYRNPSATRDAFRDGWFCSGDIGVMRNGKFYVVDRKKNAATDVVRKHQELLKYKGLQVAPAEIEGLLVEHSLIKEAAVIGLPDPSAGDLPCAFVVPEEGGSLTTADVKKYVADRMAPHNQLRGGVLFVDEIPKNAIGKLLRRELRERAKKEMGVAQGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP78</accession>
    <name>A0ABR1WP78_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sphingoid long chain base kinase 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669813.1">
        <property type="nucleotide sequence ID" value="XM_066810890.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043950"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055916">
        <property type="entry name" value="DUF7493"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24321">
        <property type="entry name" value="DUF7493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="2">
        <location>
            <begin position="144"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="544" mass="58651" checksum="AEDBD8407633BB57" modified="2025-10-08" version="1">MATTRPSVADDAALLTSPTSNTLPGQAASVQPETGIKDVLVLGPGMSLAFKGDSLVIKDKTLTKKQRSRICGIPIGASPSEYVVPFYNVLWAELLGNAVFIDIATMSKKQTRPLKLTFAIHDVSEAAITPWIEELLNRAYAGAQRRKRAKVLVNPHAGPGGAVKIWDNEVKPIFDSARMALDIAHTTFSGEAVGLCRELNIDDYDVVIPCSGDGLPHEVFNGLGKRPDARRALQQLAVAHIPCGSGNGMSCNLNGTPNPSLAALAIVKGVRTPMDLVSLSQGDNRILSFLSQSLGIIAEADLGTENMRWMGAARFDVGVVQRIFAKKTYPCEISVKVEISNKDEIKSHYKKEYESVDHTTRKEATSSGRAESTEDDSMSTSAESGDGLPPLKYGTIKDKVPGDWETVTLENLGNFYCGNMAWMAPNANFFSAACANDGLMDLVTNDGNISPLKYLDLMTSVESGQFFDKPATSYKKVVAYRITPRSKEGYISVDGERVPFEPFQAEVHQGLATVISKNGKYEAPGPMGWEKADLAAKDTVAAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPV8</accession>
    <name>A0ABR1WPV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trans-aconitate 2-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668980.1">
        <property type="nucleotide sequence ID" value="XM_066810057.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043117"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="32"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="266" mass="28713" checksum="4CC503A7BB619D18" modified="2025-10-08" version="1">MGDTKQLAQTYTVVNNTQYDAGLFLLDRLALEPGMRVLDVGCGPGNLTAHLADVVGEHGSVVGIDPSAERIALAQETVVGAGKNKNLAFHVGCAEDLSRFPDASFDVLYCNSTLHWVADQPRALREFGRVLKTGGRLGVSGQSGDFMAAHQRIKDEVLAREAYRGYDHNIAGEPRFLKQQEMGGLLDAAGFGGCTFTINKISKSTKDGAEMVDWLASSSSGKTFGGVPVDMRPKVREEMITEWDKMTTKDGLTMELELLVTVATKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPX7</accession>
    <name>A0ABR1WPX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_006798</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="3 8"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670036.1">
        <property type="nucleotide sequence ID" value="XM_066811113.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044173"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364315" description="Mannan endo-1,6-alpha-mannosidase" evidence="11">
        <location>
            <begin position="21"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="439"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8085527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="493" mass="54228" checksum="B201AECC1BDA2E80" modified="2025-10-08" version="1">MHFAASTLACLSALVGVSNGALSVDFGSKDSIKQAAKLVATDLMAFYKGDQPGMLPGMLPGPASTTGQRDLYFWWQSGAMWGTMIDYWHYTGDETWNDKVIFGLLGQAGENHDFNPSNWSLQMGNDDQAFWGMASLGAAETKFKDPPSSEPQWLALTQAVWNEQQKRLTTGFDKDCNGGLHWQVFSGNQGYDYKNTISNGAFFNMGARLALYSDNHTYADIASQTWDWLQGVGLVDKDWNVYDGANTGPDPETGKERNCTNINKLQYSYNAAVMIQGAAVMYKYVSNHSFPCHSVLGLWQEKADDWNPYEQTKDDIWASRVESLTKRTLEFFFPNGTAYEPTCEHALCTMDATSFKGYLHRWLGYAVQMVPQVRDTVMPVLESSAKAAVKTCTGGDNGRMCGFRWSSGAFDNEVGAGQQMNVLGALSVLLMDDAPPLVTSQNGGTSQGNPNAGAKDRNPAELRDITQGDRVGAGFVTLFLLLAGIGTYLWMDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQI9</accession>
    <name>A0ABR1WQI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006959</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670197.1">
        <property type="nucleotide sequence ID" value="XM_066811274.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044334"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF3">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="518"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="623"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="661"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="704" mass="76676" checksum="72630B051E6D84D8" modified="2025-10-08" version="1">MTTPVIHDHTVPLADTAVTERDADTYRESLAPKPPVSDDSDGAHHTTNEKEVLSHPRLSNDTNEKEAVMRVSEAEHEVEVFDLYKPLPVLKGVKRNRLKTGFTFPAGMFGSIFGFAIIKSISKAVPENTPILGGSFGPQENSIIQAAAVGAGGLSGIFEDFGRILTLTLVGSFFGLFFAVPLRKFFVINVARELKLMFPTPTATALTIRSMHAVGSGAAEALAKVKALGYAFTGAITLRVVSDYALGILWDWHIFTWFFIWGNYNNYAIVIENWGWWIEWTPAFIGSGLLVGLNVGISYFLGSFAAWGIIGPLLVYTGEAVGVPLTSPEDGELHEKWHRSMSYFTMSNIQDPDVTPSPRYWLLWPGVMVLLCYSMAEFVFHWKILWFGLKYAWVDTAGTINASLTKRGKASPWLEKQSNKSVNDNGNLVEDFATKDQQVPAWAWSLGALVVIIISVIIFEVQFHINGGLAVLASILALIFAFMSIHGGAVTDVTPLTASSKASQLVFGGVTKGHDLQFYAQCCGCIIAMFLAPGIFVLFAKAYPCILDLSNEKYKGHCEFPAPSVTAWKAVAEAVTAPQFRIPLSSGIFAIVLGVICVIQVAVKRYYLVGAREKYRDWLPNWMSIGVAFVLPATQYSTAMLMGAVISHVWNKKNPVTWDRYCFAIAGGLVAGEGLGGVIQAILTLAGVGGKLKGSQIACPVDSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQT0</accession>
    <name>A0ABR1WQT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peroxidase</fullName>
            <ecNumber evidence="11">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_007049</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670287.1">
        <property type="nucleotide sequence ID" value="XM_066811364.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044424"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF48">
        <property type="entry name" value="PEROXIDASE 16-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 11 13" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044956113" description="Peroxidase" evidence="11">
        <location>
            <begin position="18"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="12">
        <location>
            <begin position="60"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8085778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="272" mass="28715" checksum="D0832589401FBE63" modified="2025-10-08" version="1">MNPLRYLILFAACLVAAVPSDVAPRHHSDCPSVWGKVAKDLKKTLVGNDGRLNDNGRASVRVPFHDCFPAACDGSIILANECTDRPENGQMIPICGILGQKANDYKVGVADIIQLAGALSIRAAGGPSIGFLAGRQDSTTANPAGQMPDQNDPADKIIGAFRAKGFSPNELVALLGAHTVAKNRAGQALDTSDSRFDNVFYSETTNGRAPATLNSDKAVSNATDTGRTWSNFARSSDGWLSTFIPAMQKMVTMGNDAGSLTDCSSVITDTFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRA0</accession>
    <name>A0ABR1WRA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 19">Autophagy-related protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">PG997_005814</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(out)</text>
            <dbReference type="Rhea" id="RHEA:67920"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)</text>
            <dbReference type="Rhea" id="RHEA:38571"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3 19">Preautophagosomal structure membrane</location>
            <topology evidence="3 19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 19">Belongs to the ATG9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669052.1">
        <property type="nucleotide sequence ID" value="XM_066810129.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043189"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007241">
        <property type="entry name" value="Autophagy-rel_prot_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038">
        <property type="entry name" value="APG9 AUTOPHAGY 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038:SF10">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04109">
        <property type="entry name" value="ATG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 19" id="KW-0072">Autophagy</keyword>
    <keyword evidence="14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 19" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 19" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="447"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="537"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="637"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="63"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="112"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="738"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="825"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="847"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00024631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU364027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK8084543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="877" mass="99843" checksum="03D3507346A11368" modified="2025-10-08" version="1">MAGNLFSRFVPGKDDRAYYDQLPDDHDVDIENRAGLALDEENLTHDFHDDDLHNVRGLGLEDSRISSGSVIPPARDARSAPGRRHRHDAGTRWLSVDDDGDNEVPASLLVEHNSAPATGSNPRRTGAQPSRHAAAPGPSSRRSQAQWETAQIQQPLHPDDDYGHPLRGLQPNGIPARRGGLDVNPRDKAMYRWANVQNLDIFIGEVYNYYLGAGLWCILLDRVLHLLKVVFIAILLTLLSQCIDFSKIRDSKSLSQVMIPKCTKNMWGIWNLGLWLCSFYVVWQTIQFALDIPRLMHIRDFYTYLLEIPEEDMQTVSWQDIVSRITGLRDQNVKTASNITPSQRRYLSKQLGRHMVSQSKERLDAMDIANRLMRRENYIIALFNKDVLDFTVPIPFLRNRHFFSQTLLWTLHFSILGLVFDESNQVRPQILKSDHRGQLSRDLRVRFAFAATMNLIFSPFVAMFLLIDFIFTYYNVGIQDECLFLRRTTVHPLAEWKFREFNELPHHFKERTNLSYPFAKHYMDQFPKKKTESAAKAVRFFAGALIAIIAIVGFSDPEMFVDFDVFPGMNALGFLAICTTTWAVANGMVSEENDVFDPEYAMESVIVHTRYEPDHWRGRLHSYDVKAEFAELYKPKIVIFLEGILGVLLTPLVLFFSLPKCSDQIVDFFREFTIHVDGLGYVCSFAVFDFQKDPRNTKKQGATPSDAREDYYATKHGKMQASMIGFLDNYVYNPRSGLPGNHPMGPAGRHQFHPPPAFPGLNSPTLAADMRASRMGRADATRSRAPHNAHQAGKTPRCGPALPQPSPMASMLLDPHNHPASSLVATRAHQRPRQQRAPYLGEGASRRSPQTMPVQQARCNDTEQHSAKKMWKKVWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRI9</accession>
    <name>A0ABR1WRI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PRP1 splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006115</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669353.1">
        <property type="nucleotide sequence ID" value="XM_066810430.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043490"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010491">
        <property type="entry name" value="PRP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06424">
        <property type="entry name" value="PRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PRP1 splicing factor N-terminal" evidence="8">
        <location>
            <begin position="12"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="56"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="903" mass="100735" checksum="A47A165583D23C05" modified="2025-10-08" version="1">MANRQSFLDMPAPENYVAGLGRGATGFTTRSDLGPAREGPSEDQIKEALAKRAAQLGFGDAVKKDDDKDDNANDERFQDPDSEVGLFAGGIYDKDDDEADRIYKEVDEKMARRGKKRREAREQAEKEEFERNNPKIQQQFSDLKRALGNVTDDEWASLPEVGDLTGKARRAREARRNQRSYAVPDSVIAAASGAGELGSIVVDGPESSGASAEGTMTNFAKIGEARDKVLQVRLDQASQSSGTASTVGSASSIDPKGYLTSLAKSQLPESAAQVGDINRVRELLNSVIKTNPNNGPGWIAAARLEEMAGKIVQARNLMAKGCQQCPKNEDVWLENIRLNEGRNAKIIASDAIKLNNSSVRLWVEAMKLETDPRSKKIVIRKALDHIPESEALWKEAVNLEEDPKLIPRSLDLWLALAHLETPENAQKVLNKARKHLPTSHEIWIAAARLQEQLGTATKLNVPKRAVQVLAKEGAMPKREVWIEEAEKCEAEGAIVTCGLIVQETLGWNLDEDDDRKDTWMEDARSSINRGMYITARAIYAYALRVFPTSKTIWLAAADLERNHGTKGELWAVLEKAVNACPRSEILWMMLAKEKWMAGEIDNARRVLGRAFKQNPNNEDIWLAAVKLEAENNQIQQARMLLQQARQEAPTDRVWMKSAAFERTLGDNDAALDLVSQALDQFPAFPKLWMIKGQIYEDIGKPLQAREAYGTGVKACPSSASSPKARSVLDRARLAVPKNPELWCESVRIERRAGNTKQAEALMERALRDVPKPAQGALWSEKIWHLTQRPQRKARGLEAIKEVDNDPTLLVAVARIFWGERKLDKAQNWFEKALVRDADLGDSWAWYYKFLLEHGTSEKRDEVVGKCVSVEPRHGEVWQRIAKTPANSRKGVEETLKMVAAELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS04</accession>
    <name>A0ABR1WS04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_007032</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="3 8"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670270.1">
        <property type="nucleotide sequence ID" value="XM_066811347.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044407"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047246779" description="Mannan endo-1,6-alpha-mannosidase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8085761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="49067" checksum="6FBEC79DF30A2F50" modified="2025-10-08" version="1">MRLPGWTAAAGLLSLPSALAALAAPDFTNLDSIKDTAAEVAKDLLSFYKGEDPGWVFAIGILPGPPPDGDYFWWIGGAMWGALLDYRHQTGDTQYDRIITRSLVEQSGENKDFMPANWTATMGNDDQGFWAMTAMLAAETNFPPPPAEAGLDWLALVQAVFNEQTMLERRVNIPGNNCNGGLRWQAFSINNGFDYVNTISNGIYFNLGARLARYTGNDTYAEYAEKTYELLERLKYIDEEGNVHDGAHLPKDCLDVNKLQFSYNAAVMIQGAAYMYDVTNQSQKWKDRLDLLVDRSLAVFFPNGVAYEYACEGVGSCNVDMRSFKGYLHRWVSQATVLAPHLRDRVMTVFEGSARAAVAACDRGDNGQMCGFEWTRNGGAQSPKQTSAVHQMNVLGALTGLMMKEAKVPVTNATGGMSKGDADGGAACRTCVRWRKSPWAIGLGRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS34</accession>
    <name>A0ABR1WS34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007121</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670359.1">
        <property type="nucleotide sequence ID" value="XM_066811436.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044496"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045358446" evidence="3">
        <location>
            <begin position="30"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="180" mass="19683" checksum="5704C1F87FCFC898" modified="2025-10-08" version="1">MPLLSKIGLAVFMCLSLFMLACSIIRAAATHYQGALDAPWMSFWVHGEACIGVVMASITVYRSVLIGSGKQLGKVQKYLEKLIRSREPESVGQVNNQAGTTRSRFGRLLLSKIPTATLTGLATLFAESTRIQGPSGHMTNNSGLELGDADYHEHLRDTLYRSDPKATSGSDRQQSQESRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WSA0</accession>
    <name>A0ABR1WSA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006984</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670222.1">
        <property type="nucleotide sequence ID" value="XM_066811299.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044359"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="94" mass="10698" checksum="127F5E6AC4B6019B" modified="2025-10-08" version="1">MDSKPCLSRKVKECKARFNACLDIPSLSQNDWLEEKFAVFNWWTAALNADKTDSSSLDYRLSLRPDVIDEIVNLLEGLMHALSECEDIGKSYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WSC0</accession>
    <name>A0ABR1WSC0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670372.1">
        <property type="nucleotide sequence ID" value="XM_066811449.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044509"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="527" mass="57902" checksum="5D4445F2F8AF36A2" modified="2025-10-08" version="1">MQRLNPWASAAAQPPTIETDEIFPLHFLDNKMGQLLLVLSQTLLFHSVLDPTKLHDGLVRLVSNGDWRKLGGRLRKQPNGLLELHVPREFTAERPAVLFSAETLDMPISEHPVGGRLPRAAAETEEEGSSSSSSRGPSLHPGSTEFKEFSVGPGWCTKQDDYLCRDNPVLGIRVIVFADATVVSLVVPNVVAGALGLQSIFKAWSAALRDVNAIPPLLGAREDVIDSIGGEGQMAEPYALLPKELKGWGFVKFISRLVWNMFWRPTVGSRSICLPRQFVSRLREQCIREAEAAANKDEDGKPVFLSDGDVLTAWIMRFVVRARGGTRPALASNAVDLVGRIKSLRDTVADGGVYVQNLAGAAFTDIGVDLAINRPLGEVALAIRGSIQEQAMEAQMRALIGMYKADGLGQQKSLFGDPDAQLVIYSNWTMFDLFNACDFGAAVVKSPEAETSPSSKTGSDNDATTNTPPGKPAYMHLRSVEDSRFHRDAFFIMGKDLQGNYWTTAFVYPEDLAPLEEYMEQTWERIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYG9</accession>
    <name>A0ABR1WYG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cullin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671068.1">
        <property type="nucleotide sequence ID" value="XM_066807450.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040510"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1030.10">
        <property type="entry name" value="Ring Box Chain A, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cullin family profile" evidence="4">
        <location>
            <begin position="446"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="802" mass="91978" checksum="08D150146364D2AB" modified="2025-10-08" version="1">MALPLRPAPAVPTSNYFFTLQPIVTPNADEFQFNWQQLESALRDIHEKNASGLSFEQLYRYAYKIVLKKAGDRLYENVKQFEERWFTDKVCPRIFELISRNLVAMTLSDVPGSSVVERRSMGERFLKGIREAWEEHNTSMNMTADILMYLDRGFTQGQNRPTIFAATIGLFRDHILRASTQESDCIVFDIFNATILDQINMEREGDVIDKGLLRSCTTMLESLHKTDEENEDEKLYFEVFEPVFLDSSHAFYKNECDRLLQEGDAATWLRHTQRRLDEESDRCATTISLMSLPRILAVVEQELISKHLEEFMNLDGSGVRAMIDNDRVEDLKLLYQLVSRIDPNKTALKSALSTRIIELGREIEKVLAETDFTIIADGGSATNGDKSKNKRNTSAQLTAAAVKWVDDVLTLKVRFDRLLSVCFADDLTLQTALTKSFAEFINRFDRSAEYLSLYIDYNLKTGVKDKSEAEVELVLEQAITLLRYLENKDKFETYYQKHLGRRLLHQKSSDLEVETEMISRMKRELGNSFTYKFEGMFRDISLSKDMTEAYAKHVRGLGATSNDQIGLGINVLGGNNWPKDVVGRYTGPDQAGPSINFPVEIRALQDSFYSFYSKDRTGRKLTWIANAGTAEIRAFFPRFPARKRIQEKTNIPQTDLVNILTGLSAVKNRRILVKDPNPQSKSGPGDQFTFNNAFHSPTFKVKLAHVNVANQVENDEERKETDNKMLETRKYVIDAAVVRIMKQRKELEHQQLVMETIQQISGQFKPDLSLIKNRISDLIEREYLERFELGAGTGRASYRYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYJ7</accession>
    <name>A0ABR1WYJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase assembly protein COX19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003175</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for the assembly of mitochondrial cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the COX19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671108.1">
        <property type="nucleotide sequence ID" value="XM_066807490.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040550"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051383">
        <property type="entry name" value="COX19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21107">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21107:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="93"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13556" checksum="E6901FAF735959D9" modified="2025-10-08" version="1">MSSFGSPGGAVYTGKPIPPQRGSFPLDHDGECKEVMSNYLECIKKAKGMNDPSCRELAKGYLSCRMDNFRDPEDRFTDGPGPRSRNLMAKDEFKNLGFAEPKPKTPITTKEPEKGVKGELLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZN4</accession>
    <name>A0ABR1WZN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671484.1">
        <property type="nucleotide sequence ID" value="XM_066807866.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040926"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="348" mass="37645" checksum="57FEE7D52F76BEF7" modified="2025-10-08" version="1">MAAPTIDAPEPDIPAADAGPVNSPVTPSSQDALARFEFETGRGNEGTKILLVEWNPATGDSGKPDAPVCSEQDGWEVSWEGKTTKIPAQSERDGSETQRVYFLIPSDITVPPVIQISHFRSGRVLSTKPMPAIYTPALGVDTRKDVGKRGVLHTIWFVQPPKHDRIYVMNLKCNKAKKRMSQLQDEIRREMGNNSEGIALVMAVQERDWIAEHFGLPNPDAAGQAPDTRHIPPTPQSPRSPVGGRLGEKLRGLKLVTNASDFTTSSPSHQQHHLYSLSPDTSDIAIPSTTAFAAGVAKMGTPGTVASLNAIVSGDEPGAKSQETEDELFMLPMSPRSPEMKKSPFSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZY6</accession>
    <name>A0ABR1WZY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003694</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671627.1">
        <property type="nucleotide sequence ID" value="XM_066808009.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041069"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="389"/>
            <end position="409"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
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            <begin position="438"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="557"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="457"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="508"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="557"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="761" mass="85724" checksum="E90C9FA7CB613BD9" modified="2025-10-08" version="1">MATKQDSGTAFNAPAGSTVAPSSASTAKSEHSSASTPKERPDAPDSENTATVPVRDKDSFNDYTISNIITKDHVHAAAMVTDIEKQTKHIKHVKNMIGDYKLVRDTYRAWFTPSRLYGEGYSGYGNGRTEIGSTSRVLYPSQKPRPGTRTTPAFKWKRKDMKQQAEQHEELVPVRLDVDWDKIRLRDTFTWNLHERLAAPELFAMQLVEDLGLKPPAAQPVYEQVLQQMHEQLNDFYPFVFSDEDALDPELPYSAWKNDEMRILIKLNITIGAHTLMDQFEWEINNPMNSPEEFAASMAKELSLSGEFATAIAHCIREQSQLFTRSLYSIGHPFDGRPIEDADLVNAFLPSPLPTVFRPQQQAKEFAPYLYELSEAELERNEVIFQREQRRQKRSVNRRGGPSLPDLKERQRTIRTLVVSSTLPGAVTDVEDSRLYKKVAGAPGTGRKRPGARDGEISDSDSSEDSSPDSPAASQLAGTARTRGMRGAASAAQQRMANLGRSETPEATIHHHETRVSRKFGRELTREGTEEPQHYWVTLRVGKDRLKRFFRDLKTRQTSLAGSQTPSQSHARAPSVSHQTSMPPPRRRTHHMLQLRLQSRKPLEVHHLVRLVVLLLLPASTRWCPTPSSKTFCPFCPRASAPFPCQPSFFLPLVQHPPPPAWLTDALQKFKETDTYANDSFEGTMRYSAVDNTTESPAPMPQPGAAVPPNLRFYFLPRIRCLDCPGKLYTPGPDMSAENFLVHLKNRSHREKVEARLAKGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X038</accession>
    <name>A0ABR1X038_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671685.1">
        <property type="nucleotide sequence ID" value="XM_066808067.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041127"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="251" mass="27986" checksum="8C6144F26580511E" modified="2025-10-08" version="1">MQAICDILSQLSMLQSSVKSSLSDFMNEELTNTLLLLIKTSLASILSTISYQNTKPNTLIMSLTKLNTTGVYVVEVTPSGAPFFEALWKHYAPQFNDLPSSSTSPLSSSRELPTYIIATKKLDQTEEDDDHEKHSKKSEQSESSDSKLEALEQFLKDLPPHPDCPIASPLKLQQKPTPGRRHRRRSSKLPGLQEVKDLADAEDYKRNRDMRTYAQIAAHPRHPRPYPPSGSATTEANALAQRPVPSTWAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0M2</accession>
    <name>A0ABR1X0M2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">valine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_003868</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671801.1">
        <property type="nucleotide sequence ID" value="XM_066808183.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041243"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00817">
        <property type="entry name" value="ValRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="entry name" value="Valyl-tRNA synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004349">
        <property type="entry name" value="PRK05729.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF109">
        <property type="entry name" value="VALINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="13">
        <location>
            <begin position="136"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="14">
        <location>
            <begin position="804"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="domain" description="Valyl-tRNA synthetase tRNA-binding arm" evidence="15">
        <location>
            <begin position="1016"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1014"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8088907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1086" mass="122171" checksum="49D57E6AB0C0B58E" modified="2025-10-08" version="1">MATNSGRGNPIAADEGPSKTAEGAPPPVSNTTKDALQNAGPADGAGTHAPAKTKPKVKTEKELERERKKAEKQAKFEEKKKAKEAAAAQAPAASNKAKKPKPPQARGGASAPKKRLKSLDDPHFKAYDPIAVESAWYQWWEKEGFFKPQFTAEGEVKPEGKFVIVIPPPNVTGALHMGHALGNSLQDVMIRWNRMHGKTTLWLPGCDHAGISTQSVVEKMLWNREKKTRHDLGRPKFIERVWQWKEDYHVRINNAQRKMGASTDWTREAFTMDKNLSAAVTETFVKLHEEGTIYRANRLVNWCTQLNTTLSNLEVVNKELPGKTLLDVPGYEKKIEFGTIHHFKYPIEGTNETIEVATTRPETLLGDTGIAVHPADDRYKHLVGKNAVHPFIEGRLMPIVADDYVEKDFGTGAVKITPAHDPNDFALGTRHNLKFINILTDDGLMNENAGPYKGQKRFDVRYTIIKDLKEKNLYVDWKDNPMTVPLCDKTKDVIEPVMKPQWWMKMDDLAKPALDVVKNGKIKIRPESAEKSYYRWMENINDWCISRQLWWGHQCPVYFAQVEGEESDEGDSNRWFSGRTEEEAQAKADKALAGKKFTLKRDEDVLDTWFSSGLWPFSTLGWPNQTPDLQKLYPTSVLETGWDILFFWIARMIMLGLKMVGEVPFTEVYCHSLVRDSEGRKMSKSLGNVVDPLDVIAGIPLEELHSKLLVGNLDPKEVEKATKYQKTAFPDGIPQCGTDALRFCMANYVTPGGGDIAFDIKVMHGFRRFCNKIYQATKYVLGKLDKDFVPNKTGKLTGKESLAEKWILHKMNACTKDINDAIPAREFSKATGAIYVYWYNQLCDVFIENSKALIQEGTKEEQESATQTLYTALESALTMIHPFMPFLTEELWQRLPRRPSDETPSIMLAKYPVYDPELDNPAAAEAYELVMGCSKGVRSLMAEYALKDEAKVYIQTYDETAHKTVAEQLASIKSLSGKGVTSVEITPGTESRPAGSVAFPVSSAAAVFLHVKGRVDLDAEIDKASKKLDRTRQAIAKQQKLLSDPKYIEKTPQNLQEDARRKLGDFESEAKGFEGTIKQFEDLKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1F5</accession>
    <name>A0ABR1X1F5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine esterase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004182</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672115.1">
        <property type="nucleotide sequence ID" value="XM_066808497.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041557"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF65">
        <property type="entry name" value="ESTERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="5">
        <location>
            <begin position="9"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="338"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="437" mass="49727" checksum="E550F7EC823EBB37" modified="2025-10-08" version="1">MDYSGGSINADHLCVVVHGLWGNPNHMKTVAKTLRDAYSDDELYILLAKRNSGSSTYDGIERGGERVCEEIQEEIKKIRANGGNITKLSVVGYSLGGLVSRYAVGLLHAKGILDELRPMNFTTFASPHLGVRSPLRGWHNHVWNVLGARTLSMSGRQLFTIDNFRDTGKALLSIMADPDSIFMEGLARFKRKTLYANIAHDRSVPYYTACIAKTDPYRNLEKVKFNYVPGYEDVVLDPINPVRPSLKPDGMTLESLTNNGLWYLKNAPKITLIAVLVPIAIIGFLINSVIQNSRSSKRIKLYESGLAGIEPGKYRVPVMMQELRQRVEGAYEDINNSQHQEYLASSDDENEREMNERDRKTLARERRMSHPQWPTLALAPYQFDMINQLDSLGWHKYPVYLRKNHHTHAAIIVRMEKPSFVEGYTVMKHWIQEEFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1F7</accession>
    <name>A0ABR1X1F7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear pore complex protein Nup85</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004181</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the nucleoporin Nup85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672114.1">
        <property type="nucleotide sequence ID" value="XM_066808496.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041556"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011502">
        <property type="entry name" value="Nucleoporin_Nup85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373">
        <property type="entry name" value="FROUNT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373:SF21">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07575">
        <property type="entry name" value="Nucleopor_Nup85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7 9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="492"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="140"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1077" mass="117813" checksum="02533E36B9A6C92A" modified="2025-10-08" version="1">MSYRLPEVSSPATPERKQSHYNGEHPSTTPAGQAQPSPAPSFTPMGEPSPSYLTSSIGAMAGKIKAPNFGRPNIGGASKSRRTPNVPLGSSLRGSTTSRQPSGLGKHSYSVLDDLEDSDEGADNAAPASQPGTYGMHFDSDDDDDEDDDDDDIMGAQEDEEFDDDEEDAEGEDDIDAMVEDEGDYDIEDDLVREMEATDYSGNFLGGGDTMDLLMGTPAANKRMQKEAGDIFRASSMRSLFGRRRDSKYSAVAKDLFTQLGHARVSEPHSLILQTEEVIARLYDEGVGAEDDTDKLDMTLAGAADYLVRDVWEPHAKFLPKSNEEHGATIGPGPNSTAFEKAAFIAAMVFQDQFGNFQPVTLPQTLFEWQQEYHNPSDGQVDSILAHRPSPASHGLFWQAIYMSLIRGDVTAAIKLLRNAGWNQVRKGSRGEPAYTGQPLRNIEKVIEDACHIMELCPAVADSNWDIQESNWTLFRLKATAAKESLVQFAEGKDQPPPAARRFAGSDFGESEDGHGAMARLARKAQSRLPWDVYESLQSLYSILVGDVEAITAGAQDWCEATIGLFGWWDDGHHNRRLGLSRSQSIMGEPSMKDDALVRLAQCFHAAMESDFHFNGLDSVEVCISSVFEGNIDGVVGFLSSWSLPIASSVAEVASLGRWLPPPEPQNLISMDNFDADDLEVLGMNQGISGNQDGVKDSTLVSYARGLNDIKQLTGSVKKRGGVVARVTRDGWEMAVQIDLVNDLLHDILEKIQPDSHETVDKIWALLNDLGMINFAEDTAEKYGDVLKKETFRFGEMLWYYALAHRPGKIRDVLNGLMSISPCRVHDLPPDSELDARLKSLLQERTTTLEQFAKQDLEAAELLGKMLSGYATLRKFYELRDGNGKSTSVSLARRQQAATALVFVVASADDNIRGGLYDDTRDAVVSEDFILALLGEASIFVNQNPTVITLEQIDTLLKAVEDIETVGSRVYEAADAFFQIVLSSGQGKGSTPGDLMKMSHASLGGSFVMTGSSMMASQLHKSIRNSGVLKGPIKRSWDWRTEVLASSSSADILKVIRLGLTKDLANLWLEQADSIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X247</accession>
    <name>A0ABR1X247_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672393.1">
        <property type="nucleotide sequence ID" value="XM_066808775.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041835"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="258" mass="28892" checksum="8021349E08E22D52" modified="2025-10-08" version="1">MPIRNPFATLVTRRPGNDENLRPDLLPPTKDAAHPGFERVDTVGSKASSALSMRSAKNQDNGDYKMSVVNDSGVYLPPSPSEEKGLWPRRPAAPSRTSMDTRSSIGDIEHFSISRESFDSYRRSFFGRALTYHAGYLGQVSGNRPRPPRQSLDSARFPRMPRSSVRDRFFDPEPPTAEEAFEEVGLNDDQKQPPQQQPRKRGFFAKFSDASEPNTHSHTQGMSRFIPGRKRAQSGQGAELGNMERPKSSHSQEGEEMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2S8</accession>
    <name>A0ABR1X2S8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672590.1">
        <property type="nucleotide sequence ID" value="XM_066808972.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042032"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="165" mass="16088" checksum="A27AA766245A3EAD" modified="2025-10-08" version="1">MPSRTPSEIVTITCPPPSLPSSSYNPKPSHLPHELLPNDADLRAARVHEGGVEVAGAHAADVVEAPAGGAGAGALRLGRVAAGAGRVARVVAALVGEGEELAAGQALVVGPAAVVLAVRAPCYQARARALAEEAGGGVVGAGASGEGLARDRGVAMVWSGGGGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3P6</accession>
    <name>A0ABR1X3P6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672905.1">
        <property type="nucleotide sequence ID" value="XM_066809287.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042347"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="118" mass="12659" checksum="3CD182AF90700496" modified="2025-10-08" version="1">MHGPSTVIVASCWPSPGLFPGSDTAVREQSKRRAEIVRQYEPTLPGRSSASCDVSGVDGFSYRKEDFDAPHGANVGEGQERRREIVAHPTTSRLAPSSEPHRSFGAENGKPPGDAAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X438</accession>
    <name>A0ABR1X438_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sugar porter family MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_005127</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673060.1">
        <property type="nucleotide sequence ID" value="XM_066809442.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042502"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF5">
        <property type="entry name" value="ALPHA-GLUCOSIDES PERMEASE MPH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="403"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="36"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="535"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8090166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="575" mass="62963" checksum="8A0C0B3555016E5F" modified="2025-10-08" version="1">MGDVPITTGDASRAADNEKNMTLKEALRVGKKGILWAIVCASSTVMEGFDLALLGGFYAYPAFQMKFGNLYKIDTDGTKHYEVPAAWQTALSAGAQIGQIMGLCLSGMAAQRFGYKRTVITALLFISVFVFIPFFAPSLEVLLVGEVLQGIPWGVFEAMPASYAAEVVPLAIRPYITTYSNLCWVFGQLLATGVLRACLTMGGENEWAYRLPFGLQWVWPPLILMFMAFAPESPWYLEKKGFGDRAKLSLRRITNYNEQQIQDAYENIKHTVVINRQCQGDSQTGSPKGNIKTALMEFPRCFEGQDRRRTEIACGTWISQSLCGSSLMGFAPYFFQATGLSAEAAFSLQLGGLGLGVMGTLLAWVFMSYIGRRRIYTMGLGALCALLLLMAILSFAAMDKVGVPWTVAALLAVYIFVYDSTVGPCCYSIVTEVPSVQRRAATVALARICYNLCGIFSVVMNPLMLNPTSWGWGTKSTIFWTALCAMCLAWTYFRLPETKGRSFAELDLLFHQGTSARNFQRAVVNPFTTCVLDVGEPDGRVSTPSTPGSQEKETGGVSIPSTLGGQERVVAEHKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X459</accession>
    <name>A0ABR1X459_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-glucuronidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673033.1">
        <property type="nucleotide sequence ID" value="XM_066809415.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042475"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="2">
        <location>
            <begin position="401"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="56252" checksum="6435950DB4044DA3" modified="2025-10-08" version="1">MLGLPQASRPIPDNNKNVNAKRATQTLKIDTTKPTDTFTVPADFVGFGIESAFLNNFHNDFSANLVSSLRQRMSQPPVIRVGGTSGDKFIFDPDQKEVKKCVAGDCPQGSDATYRLGPSFCEGYKAFPNARISIQAPMQESPTPMNNTLAFVRCAWDARGGDASKVAAIALGNEPNFYKDTTAADYAKEALRVQKAVIDELGLKGDGRKFFEVANTASSQDAKFGVADVLKAGINENKLSNSAADHYYQIAGKHDWTDEEMQNLMLSHRAITDRLQNRYAASIAASRAAGLPYIMSETAAVLGGAPLTFMSGFGYGLWAVDFGLACMAHGVSRVMNLAGRPVAGRTFWVPDPTGGDKSPGPQVRAPYPGAIFLTDFVGKGEGLGAVKELDLGVTEHPFLSAYAMYDAQQGGELQRVALVNLRLYNGTRTPNDQRGVETFRVPVPQGVQSIKVRRLHADRGAAAMGFDFGGMEHNVTWAGQQWSYSIDQGKGHGNVAEDKVQVQNGIAAVNVLDSEAVIVFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X819</accession>
    <name>A0ABR1X819_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673574.1">
        <property type="nucleotide sequence ID" value="XM_066806278.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039338"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="77" mass="7683" checksum="F030D8137CA05F67" modified="2025-10-08" version="1">MPELDLDQAGADGSGQGHGSGGGTNSNNTGNISNTGNNNNGMRGTGAATESMNIEPSDLTDLTELDNRSASVEDQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X843</accession>
    <name>A0ABR1X843_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002012</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673623.1">
        <property type="nucleotide sequence ID" value="XM_066806327.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039387"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07722">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047921">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041516">
        <property type="entry name" value="LACTB2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050662">
        <property type="entry name" value="Sec-metab_biosynth-thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131:SF0">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17778">
        <property type="entry name" value="WHD_BLACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="51"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8091651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="319" mass="35221" checksum="F6BF47E484B3D573" modified="2025-10-08" version="1">MKRRASDTDPHLWRISKWHPNNSSTSPEVERLSPACLRILGGNPGKFSLQGTNTYLLGTGPRRLLIDTGHGVPTWIATLTKTLADEKATVQSALLTHWHPDHIGGVADLLEHSPGTAVYKRDPEDHDGWRDIADGQVFRVEGATLRAVHTPGHTTDHTVFVFQEEDALFTGDNVLGHGTAVFEDLQTYLQSLAKMEGLVAGRGYPGHGAVLPEARAKIAEYISHRHEREKQVLQVLGSAKGSSEDGSNDDSTTNRIARPDRWTAMELVKVIYKSYPESLHGPASAGVLQILQKLRAEDKVASEDDDRWRLLPQEDRSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8A5</accession>
    <name>A0ABR1X8A5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Aconitate hydratase, mitochondrial</fullName>
            <shortName evidence="11">Aconitase</shortName>
            <ecNumber evidence="11">4.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_002026</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673637.1">
        <property type="nucleotide sequence ID" value="XM_066806341.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039401"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01584">
        <property type="entry name" value="AcnA_Mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006248">
        <property type="entry name" value="Aconitase_mito-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01340">
        <property type="entry name" value="aconitase_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005558">
        <property type="entry name" value="PRK07229.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF3">
        <property type="entry name" value="ACONITATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0408">Iron</keyword>
    <keyword evidence="8 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="13">
        <location>
            <begin position="73"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="14">
        <location>
            <begin position="573"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="516"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8091665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="770" mass="83605" checksum="2469D4EE4797821F" modified="2025-10-08" version="1">MLATRQVLGNVARSRVMGNLALRRTMATVSDSPLDRKVKQNNWEEGNFINYKKMSENLSVVRSRLNRPLTYAEKILYSHLDNPHEQDIERGVSYLRLRPDRVACQDATAQMAILQFMSAGMPSVANPTTVHCDHLIEAQIGGVKDLERAVGINKEVYDFLSSACAKYNIGFWKPGSGIIHQILLENYAFPGGLLIGTDSHTPNAGGLGMCAIGVGGADAVIGVKLTGQMSGWTSPKDIILKVAGILTVKGGTGAIVEYHGPGVDTLSATGMGTICNMGAEIGATTSLFPFNDRMYDYLAATKRKDIGDFSRTYAKELREDDGAEYDQLIEINLSELEPHINGPFTPDLATPISKFAEAAKANNWPDEVKAGLIGSCTNSSYEDMSRAASIAQSAMKHGIKSKAPFFVTPGSEQIRATIARDGQLETFEEFGGTVLANACGPCIGQWDRRDVKKGEANSIISSYNRNFTGRNDGNPATHSFVTSPDLVVAMSIAGSLSFNPLTDKLKGKDGKEFLLEAPTGAGLPDRGYDPGNDTYQAPPQDRQSVQVAVAPTSDRLQVLSPFTAWDGKDATDMPILIKAQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAINEANGEANKVKNSTTGEWDAVPATARDYKSKGIKWVVIGDWNYGEGSSREHAALEPRHLGGIAIITRSFARIHETNLKKQGMLPLTFAEPADYDKIKPDDKIDIKCTELEVGKPITMVVRPQDGKAFEVKLNHTFNAPQIEWFKNGSALNTMAKSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8S7</accession>
    <name>A0ABR1X8S7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673833.1">
        <property type="nucleotide sequence ID" value="XM_066806537.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039597"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="337" mass="35032" checksum="A805332F92980ADF" modified="2025-10-08" version="1">MPTSQELTKNSFSTQKLAYTSPDSQAAESRSDFPQADCDATIPVGSTVAIKQTSLQTPGKNPAITVTSQSLPNQVEVYLAQLNFDIDPSLEPRWPVIPQRVAAKIIFYTTRSAMSAIRALVLFSLAAVAVADGLYVHSNELAAHFAKRQQMPEPGTPAYNCHDNCGQSIIASRGEDPCHDKAFLTDYAVCLSCAGPDNYGIWMYYGGALAKAASSCGLSTTAGTEKTTDVPQAIPAAKGSSTATSPTATPKEPTATSARPSSTGEVISTVPSSTTAGPSTTSSTSAISTSDTPPHLSLTTHTSTSSQPTTSPTVPTAGASSAVCIKLSGQQQSQGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8W6</accession>
    <name>A0ABR1X8W6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002318</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673929.1">
        <property type="nucleotide sequence ID" value="XM_066806633.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039693"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002673">
        <property type="entry name" value="Ribosomal_eL29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01779">
        <property type="entry name" value="Ribosomal_L29e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="117"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8091957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="129" mass="14597" checksum="CE19093F64911731" modified="2025-10-08" version="1">MRHLDLCSSFEPTSSPSSAAHIFEVTDSHSIDLPSDPFYFSSPVLQFRIPITKPPRLCTGTVVEMAKSKNSSQHNQSKKAHRNGIKKPKTMRYPSLKGTDPKFRRNHRHALHGTMKALKEKKEGKRETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X970</accession>
    <name>A0ABR1X970_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome CYP13A3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002284</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673895.1">
        <property type="nucleotide sequence ID" value="XM_066806599.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039659"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="579" mass="64632" checksum="E5354EF5425FDB39" modified="2025-10-08" version="1">MRVDVQFPPATASATGLLTTVLLLFVTGIVWSLLSVRYRSRLAQVLPAWLWRRVALTVPGWEVYHKSKPFDNDASVREGKSQSFVLVGPSTFEVWTVDPVAVHDVQQRVHDFEQAKALAVLLGKYGPNVITSNGERWARYRRPVATVLNERISGANFEAAVRHTEEVFGPALPLSSGHDNDDATNKINVPQLFDMITKLTFNVLISASIGDDKFPWSSEEAQGRRESGYKFTYTESLHLFLDNFYGISMLPLSVINGWPKWLTGYEKVSAVGQAITEYRQRMRSMLDLERDRLASEKQLPSQGKADLLALLVKASEDEAHTGMALTNDELVANLFVFIAGGFKTIAAALQTALVALAAYPQWQDWLLEEVDAIVSSSSENADSWEYAKVFPQAVRHVAFILEMMRLHGSSTRLTRIASGPQTMQTSGATVHIPAKTRVHVDSMALHVLPCWAGINRQSDPSFVHSKTTDTGDEYSFRPSRWINPPGSDKTHYLPPKGTYVPWGTGPRVCPGQKMAQVEITTVMLRILKDHRVEACPSLPGETKCQAEEKFQAALHDVQWGGILQLKRNKDLCIKFTKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X973</accession>
    <name>A0ABR1X973_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fork-head transcriptional regulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002330</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673941.1">
        <property type="nucleotide sequence ID" value="XM_066806645.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039705"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22701">
        <property type="entry name" value="FHA_FKH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881:SF1">
        <property type="entry name" value="FORK HEAD PROTEIN HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="127"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Fork-head" evidence="9">
        <location>
            <begin position="345"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="345"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="262"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="426"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="570"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="587"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="605"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8091969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="645" mass="69992" checksum="95131F96E3CAAD89" modified="2025-10-08" version="1">MPPTRSSQRARRVRDVSPSLAHAEMSSPSRPSKRRRRADPDPPPPPPSDPVDEEDSSLTIDPTNDNNVEPNVAADTIITRVTEHLASTETKASKEHANANHTSQGDIEAYAKIAAREWTYYVRQLNVNIGRFSEMAEDGTALAQNPEDEGFVHIDLGPNKIFSRKTARVFYGADEEKWFLECKGRNPVKVNGVPLKKDDEPHPLSSGEVIEAGGIEMMFVLPASTSRLQIHDMFISRIGPAAPQIKHSGSSPSLEARHALPAAPLSSGDRPSSSNAGRPPSSRGGAFPQPIAPAPPDYKRPGTPQSAKSRTIASAHKSPAYGSSGTMLLNNGEVDLSLEENKHIKPSYSYAQMITQAIVSQKEQKLNLNNIYRRPRGGRQNSIRHNLSLNKAFIKAPRSTDEPGKGMKWEIVPEQREEMTRQAFKVGRGGHRGSSAPSSPSAPNQLNYINHGPKDMTSGREPASARKRKASPTGSPLPSSAFNRSQMTPERSSRFQPPGSASFQDGRDTVIYHAGTPSSPATHCTPEYRSAAESAHAYQLTCAILEICRYWQHTGQAFRHQPVQAVSQLASQQQPAPFAGDDGSRSPIGSPTRSSGRAATQETTTVDEEEEEGGFDLTKGFQSIGSYHNHLGRGGGLLARANGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9E2</accession>
    <name>A0ABR1X9E2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674052.1">
        <property type="nucleotide sequence ID" value="XM_066806756.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039816"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196:SF1">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8092080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="208" mass="22712" checksum="59393F79B04C0DCD" modified="2025-10-08" version="1">MHVQSPDSFIHDLSVNMYGPYYLMRLLMPGMRAQRSGCVLNITSRAGVLSNIPFSTSYHASKAALINLTGCVQAEVDIDGLEDIHLYALHPGGVKSEMTLNKYKNAETTLPNHPALATKLTQRVDAYNDSPYLNGMTCVALATGLARHVLRGRYFDVGQDLEDVLRPEAAEAAIRADPALYTLHTRYLGAVPDSSGAVLDEPFVFPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9H4</accession>
    <name>A0ABR1X9H4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674057.1">
        <property type="nucleotide sequence ID" value="XM_066806761.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039821"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616:SF1">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539455" evidence="1">
        <location>
            <begin position="27"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8092085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="571" mass="62796" checksum="9B31278AC5396D09" modified="2025-10-08" version="1">MLFQQASWVTSGLLGLLLAVAGVSSAATELKGHAQSLLDESMDFMDKIYDRDAGYLYYFYYPLAAGQHETRSSMWYATGLLQRNRGDDVDQAVRIIRNIIGDQEKNETLQWFGDYTVYPEQPTVGHGDYKPVIYNSWDPNWRGFIGTNLIVIYEEFGAILPGDVKQLILDSLYNATIGDSYRVGGVDDDNLYPSYSNPAIMRAIASGWTGRKCGDANMTAAGEMYAREVLDLFDQNGGTLSEFNSATYMGVSLYGLTLWAKYMPAAEEDSVMGAHGARMIRQIWQTAGQMYNANLGNLAGPWDRAYGYDMNKYVAIFSLYIWTLVGKENAPGLQTTGQTWSMAHADDFEYAPLIAVLAPFHDALVPDDVVARLSAFPLSSDDEEGHHMYTTSAFSPPHDLVPRNITTWLSPNLTIGAESFRENIVGGPREDSSQWNPAVVQWTHPSSLANKKKSVGYLTLYPTEPALDAEVAPGNLSLTYPDGNVTSSFTFLVSANPLGSAKRDLVSLEKDLDGVKIEVSGSVDPVPIVTFCGLVGGSCKPIHGFEFWNFTYAMPANSTAVPNVNLIIETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9Z4</accession>
    <name>A0ABR1X9Z4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674250.1">
        <property type="nucleotide sequence ID" value="XM_066804477.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037537"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="195" mass="21682" checksum="4882700239E710BD" modified="2025-10-08" version="1">MEGAGRSDRQAPEASQGNGSRQLGGIPKLVMRDAKATCQTSPMDRMAMAISDHPSRPLLSFGALSQDGVFNRPLWHADPALDGRRLLTGLEQVVHSDGSPSYQGDDAVMLKPYWTNILDHHRFAGYHPQPFRLYIDLVWDAVFVPNASINLEYVSPRDKVSRCYWFKFSMAEPPRSDLGWHSLEQAAVCSSGPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAK7</accession>
    <name>A0ABR1XAK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674513.1">
        <property type="nucleotide sequence ID" value="XM_066804740.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037800"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431:SF7">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="25683" checksum="9E816427BC55E285" modified="2025-10-08" version="1">MASKFYALVIGAGTGTGSAAARRFAKSYPVVLMARSPASYQDAVDAINAAGGQAVGVSADAADEGSLKAAFARIRDELLPGHQLAAAVYNVGANFKRAPFLEATVEDLDGSLGGNVRGTFLFAQQTIPLLLETAAARPPHPPTLILTGATASLRGAAHCAGFAAGMAARRALGQSLAREFGPRGVHVAHAVVDGVIDIPRTKGTMSTAARRTGSWIRMRYWHLHTQPRSAFTQELDLRPYVEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB07</accession>
    <name>A0ABR1XB07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase- FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674625.1">
        <property type="nucleotide sequence ID" value="XM_066804852.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037912"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="122" mass="13610" checksum="8136C58A763BC172" modified="2025-10-08" version="1">MQPQPAFLNRKSASTGGNAFGLDSEDDNLFNVLLTITWDRAEDDALVHRQARSLLDQLEAVARDIGVDHPYVYLNYAGPWQLDAIVAGYGAESLGRLRETSRRYDPRGMFQRQVPGGFKLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBK8</accession>
    <name>A0ABR1XBK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000786</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674874.1">
        <property type="nucleotide sequence ID" value="XM_066805101.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038161"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF25">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="405" mass="44204" checksum="28367D3D33D81316" modified="2025-10-08" version="1">MERLVAVGAALRSPAADAPLVLVIGGGVTGLVNSWVLLDRGYRVTVLSSEQRLTSQIAGALWEYPPAVCGSHTDKISLAHSKRWCMTAYHIWDGIASIPALSDASGVRMMPSDFFFPAPVEADAAQHSKMVEIMASGVRGFYHGADLMTERDVDPSYGAVDAYEVIAPIIDTDKAMDWLMQLVESKGANLVTETIGEDLLDIESQLLERFDADVIINCTGLQGQRLPNPRGLIRVINDGSAFPKVEAALTITADAVHDSNEIVFLVPRNDNILLIGGIAEPHKWDLDLTLDSPIIQRMRRRCEAFLPCLKNAQVDPDYPLAQGLRPFRGNNVRVERELRNTSSRIVHSYGQGGAGWSLSFGCAQDVAMLVDEVLSGLPARPMKEMLGDRIAAVKQRFTADLRATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBN0</accession>
    <name>A0ABR1XBN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674873.1">
        <property type="nucleotide sequence ID" value="XM_066805100.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038160"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="200" mass="22009" checksum="7E06110CA482A3D8" modified="2025-10-08" version="1">MEDVPDGKVCAQVRPVGGLSICRTQDTGHDVGLSQDYRHFDENARLLPFTDDGQIREFAKPARAAWRQRLGAVSQSHTDGAAFQVGPGNLDSWETEAEMASVTATETVKPIHCLPRREETVQHGDPGTSRRRNLGRDRQYRSGIAPVASAERTTVVLQRSVQGSVQGMGVGDRRQQGPRKALPKVIQVRSFSLRVRPNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBN4</accession>
    <name>A0ABR1XBN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000677</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674765.1">
        <property type="nucleotide sequence ID" value="XM_066804992.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038052"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="62535" checksum="9E38D436C55DB255" modified="2025-10-08" version="1">MFDTSTLSSVGALSEALGITPKYLLIGLASCVGLALLSCKFVAATSNRPASPQTLGDPIPGLYNTLQFMFNNYKFMTRAQAALQGSRHSILRFSLGPKTVYLVTGQQNVHAVFGRDLVHDVTNQEQMTRYALPTLYKMNPAEVRRWEADLSGVTKAPIPGTEHVPSHQRLWYNYEHIYAEYLGKPQYMKPLVKRYDDILQQVLNSYPVGEWSTVSVQKLCRDEVTRTLVDTLFGPRLMELSPDFVDRLWAFDEQVFQLVMGLPKWLNSKPAKAHDAYVGPIERWLEVVSAGFDWDAAEAESDWEPRFGGRAVRQLYRWMKETDWRNEVIAATLGALVFAIPTTMWMLMEIIKDPSLLQAIREEVATATTTDPDSGKPVLDHQKLVALPLLQSIWTETLRLRINFNIVHDVKRPVNLDNGRTKIERGALLQVPMMVAHYDETVWGAADHPASEFWAERHIRYAIGERKFVMAGHPAAYFPFGGGANICPGRQLAKHEIFTTVALIVSRFELEVLGWTNPVNGAPSDRAAQSDLRYCGAGAMPPDRDLRIRWKRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBV0</accession>
    <name>A0ABR1XBV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein arginine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000748</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674836.1">
        <property type="nucleotide sequence ID" value="XM_066805063.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038123"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007857">
        <property type="entry name" value="Arg_MeTrfase_PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035075">
        <property type="entry name" value="PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035248">
        <property type="entry name" value="PRMT5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035247">
        <property type="entry name" value="PRMT5_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738:SF0">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05185">
        <property type="entry name" value="PRMT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17286">
        <property type="entry name" value="PRMT5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17285">
        <property type="entry name" value="PRMT5_TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015894">
        <property type="entry name" value="Skb1_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRMT5 TIM barrel" evidence="7">
        <location>
            <begin position="46"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 arginine-N-methyltransferase" evidence="6">
        <location>
            <begin position="377"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 oligomerisation" evidence="8">
        <location>
            <begin position="543"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="318"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="767" mass="85382" checksum="7A74DAA9F4F80F2B" modified="2025-10-08" version="1">MAQEYMDQTSEGYDDVRPVFYIGQHDSARSEPPTDLQYGQILNAGFGFTTTPVTNRHFYQRIQGLVASCLGEWEKSELPSCHPDPIVPPLTIEDTALFPDTYTSGLVAYSSPWIDLCSPNPVVSSISRQVLNLEVNYANFCGIRSLIVPGPRNDALKAGSGQGVAQFARAIQEALVIGTRLNFIIHLPMYREPGLEETIENLSSALPNKEQPGSDEPEEIDIFSTWDSWNVIRTTCTYDSRLSVAVRVPRVLPEKQVQTRWFSEPLQYLTFGPSSFQPNKSGNPSLSKHHQEMIGSYMKLKHAPYFLLCDVGPELKDSPETLQESAVPAEAAWPSLSEASQQPTRTTPKYFKTNPYASYLRYVESQQEPLSALERSTLSNFQDWLQSPLQPLSDNLESVTYEVFEGDPVKYNQYEAACAEALTEWAQHKKPTSSSTGAVVIAVAGSGRGPLVTRALKASETTGVPVQVWAVEKNPNAYVYLLRQNQRETSGVGHRRREPLYGKVDILISELLGSFGDNELSPECLDGIQHVLAKPHGISIPKSYTAHMSPISTPRIHADISQRLPMDPHGFETPWVVRLFQLDFVAEKVPGHARFQQAWEFVHPLPESTMTMVDARRSGGVVGGGGGSMAGGVGANDHNSRHCHLTFVCRSRGVIHGLAGYFESVLYEHMETGKTPVELSTLPNNIDRKSKDMISLFYDVWPKTNVYAATSLLPPDTELEVSMWRQTDDKQVWYEWMVEAFAWVGPTQRIKVGGSEMCSSRKIACLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBX6</accession>
    <name>A0ABR1XBX6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674871.1">
        <property type="nucleotide sequence ID" value="XM_066805098.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038158"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="135" mass="14501" checksum="EC678F5C38E43DCE" modified="2025-10-08" version="1">MATEPSKTALSTLSAWGTHSMAPTGLATLITALHFRPLQKAPMLFVPVLLFSSYINLQGFKKDSAGLTAAASGTYALLALRRSPASFFKRFGVRGAVRGTAVVLGLANLASCGWVYATADRKAEEEERRNNPRWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC33</accession>
    <name>A0ABR1XC33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin-related protein 2/3 complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000844</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ARPC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674932.1">
        <property type="nucleotide sequence ID" value="XM_066805159.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038219"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.190">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006789">
        <property type="entry name" value="ARPC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036743">
        <property type="entry name" value="ARPC5_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12644">
        <property type="entry name" value="ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04699">
        <property type="entry name" value="P16-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039096">
        <property type="entry name" value="p16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69103">
        <property type="entry name" value="Arp2/3 complex 16 kDa subunit ARPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="139"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="207" mass="22072" checksum="05A0226B8C1FFF96" modified="2025-10-08" version="1">MSIIQQHTSASLSDAWRTINIDALDPDSSQNFDTTTLHPPLPEINEADVRQLNAQVRQLLRGGDAEGALRGCLETPVYNGSESAKEAHLQTVTEVLQSIKASDMSPMLERIHQSPGGSELLDVLIKYLYKGMAASAGASGAPRAAGSRTPSTLTPQQTGFSQVGSRPGSTNESTGAAMSVILSWHEKVIEIAGLGSIGRCMTDWRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCX5</accession>
    <name>A0ABR1XCX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">50S ribosomal protein Mrp49</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001112</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675200.1">
        <property type="nucleotide sequence ID" value="XM_066805427.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038487"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040049">
        <property type="entry name" value="Ribosomal_mS25/mL61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13274">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13274:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="7">
        <location>
            <begin position="40"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="207" mass="23366" checksum="738A5282B2B44A83" modified="2025-10-08" version="1">MVNPGKRMNILKALLNLRHGPGAAILPPEISRLHMDFALRWNDGHMGPRKFWKTCLPRLKFWNPAVPMIINRSSNNAGPATLSIYFRQAAAAAAALPHPPARRPNRIRARPTSAPAPPPEEGERVVTIEMKHQHSDAILQEFLQKTGATVLQPSPDELNEMRQTEDLKDRAAIDRSIMKKYIDDKRAEERLLARAREEAEAIRLANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD11</accession>
    <name>A0ABR1XD11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001199</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675287.1">
        <property type="nucleotide sequence ID" value="XM_066805514.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038574"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF7">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="90"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="396" mass="44158" checksum="9B050986BA347D8F" modified="2025-10-08" version="1" fragment="single">MEPSELSTPDTLDFFDAGDRVAASAATGFDCEPFMNDTSSNSTSTLGDVAAGPACALTSVSSVSNNPWPPRQAAKKQRLERKGHTKSRRGCYNCKRRRIKCQETYPSCGHCTKAGLNCEYPAVPQITHQHCLLCQHEYLMHAMLGLAASDLLGKDASLLPFAMAHRIKAIKAIKKTLNDVPKSSNTFEEGNALMATCFALTFQSVLLEDGMAEFMTFCRGVVLVAIQMYCKGARFLFTNWVGKDEMGLLQPLMETVPPIRQDWVDAAIGSVRALEPLCVHPVEAEYYVLLVDMVEALYTSPSRGYQIICKHYGWWLQIPHERFQYLIDPANPVCHLLATHWIAIKQIMAPVTEKEHLVKPREKAARDQHTDMGTVRWLKYLNRQLPSGTAFTTGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD34</accession>
    <name>A0ABR1XD34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001287</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cell membrane</location>
            <topology evidence="1 5">Lipid-anchor</topology>
            <topology evidence="1 5">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675375.1">
        <property type="nucleotide sequence ID" value="XM_066805602.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038662"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF8">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045005571" description="1,3-beta-glucanosyltransferase" evidence="5">
        <location>
            <begin position="19"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="422" mass="45269" checksum="C515879AED7F527D" modified="2025-10-08" version="1">MRSSVLAAAAALSSAAVGANLPTIEAVGNKFFDKNGKQFFMKDDPLVDTDQCKLDAALMKTLGANTIRVYHVDSSSDHDGCMAAFADAGIYVTVDMDTFHTYILPENTFWNKSQLDEYNKVMDAFHSYDNLLGLYVGNEIIAQANQSLAAPFIKAAARDTKAYRDAKGYRKIPIGYSAADIAELRPMLQDYLTCGGNASENVDFFGLNSYEWCDPATYQTSGYQTLQVNASDFPVPIFFSETGCNVPGPRLFADQAAIFGPDMVKSWSGAIIYEWIQEANHYGLISYGPKVDPTVAGPNIDGGFTRKGSPTPVSPDFDNLKTQWKAINPTGVARSDYDAKSASTRECPKSTSGGWLVDGNVAVPTLGATLTGSSYSKVPSATGASDAAQPTESKKNAVSGSNEIAGMAAGLVGVMMIFTFWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE39</accession>
    <name>A0ABR1XE39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_001517</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675605.1">
        <property type="nucleotide sequence ID" value="XM_066805832.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038892"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="7"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="139" mass="14867" checksum="0770B0EFCDF22B5E" modified="2025-10-08" version="1">MASSKVAHGKCLCGTIEIEAKGDYKASVACSCKNCQICSGSVYTVNWAYPKDTITVTKGADSLKTYEDKATDSGKSVLRRFCGRCGSGIYSEIEDGNCFVKAPIMEGGVEPQPVAHIFTRNLPEWAQGNKTGNQVENGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE68</accession>
    <name>A0ABR1XE68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001650</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675738.1">
        <property type="nucleotide sequence ID" value="XM_066805965.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039025"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="6">
        <location>
            <begin position="18"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="7">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="143" mass="15356" checksum="2F815E318DF3C4BD" modified="2025-10-08" version="1">MPGGKGKSSGGKSSGGKTSAVEGPKKQQSHSARAGLQFPCGRVKRFLKQNTQNKMRVGAKAAVYVTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDTLIRATIAFGGVLPHINRALLLKVEQKKKAKAQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEA0</accession>
    <name>A0ABR1XEA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675803.1">
        <property type="nucleotide sequence ID" value="XM_066806030.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039090"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="188"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8095030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="245" mass="27861" checksum="3B821149EE4CA617" modified="2025-10-08" version="1">MGSTTSSSVGALLAKKEAPSIDAPVKNALAASSPRNRHVTLPHTAHHYHHRHHRRPSFSEDETNALTYQAKVVYLFSESLDKAKVEIAQKPQTLEARDAELTNTKCLLGTKVRELEEQGRHLADKDKDLEERNRQLTAKTKESESRGRLLEDRARELAEKDRRIAAKDKELGERKPLLTAKTKESEARAALEETKRQLGAKTRELEQKTCRLGVVEETYRKLRARYRKMKAAMVSLAEEDTDQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEF4</accession>
    <name>A0ABR1XEF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_001687</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675775.1">
        <property type="nucleotide sequence ID" value="XM_066806002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039062"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF40">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="13">
        <location>
            <begin position="193"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8095002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="507" mass="57422" checksum="92FD60ABDCA07B29" modified="2025-10-08" version="1">MIQSRRSFTATLLLAIFLVATFYTAARIGILGPSYIQPPLSIPYYHGHAHAATGANNNTDPQDGAASGASSLSSPAKDPACAWMPDTSNILVVMKTGASEAYARVPTQLMTTLRCVPDYLIFSDMKQTLAGVEIHDSLDTVLEEAKKDNSDFVLYDYQKACEVDLENCNREGGDAAKAGWNLDKYKNIHIAEKAFALRPNYDWYVFIDADTYVLWPNLVQWLKNFRPMSKHYFGSMTMISMFPFAHGGSGYVISKAAMTEFNGRPDGSVANKWDTKIHDSCCGDYMFAKAFKEATDVSVKNVWPTINGEKPYTLPFGPTHWCHPVVTMHHLNSQEISSFWEYERDFFQPHDSSARSSLSTPPQRTLLLKDIYTHFFAPKMQSSREDWDNLSDDVLYVDLSTSTDSKGRKLETWELDRAKKGPMTQVERKAHKSFEDCRAMCEAANDCFQFLYHAGVCAKSFSFKLGHPNRSEQSPAYRWRSGWNVPKINKWIERQGECKKPIWPKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEL2</accession>
    <name>A0ABR1XEL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">3-dehydroquinate synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_001697</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675785.1">
        <property type="nucleotide sequence ID" value="XM_066806012.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039072"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08199">
        <property type="entry name" value="EEVS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050071">
        <property type="entry name" value="Dehydroquinate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056179">
        <property type="entry name" value="DHQS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035872">
        <property type="entry name" value="EEVS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43622:SF3">
        <property type="entry name" value="2-EPI-5-EPI-VALIOLONE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43622">
        <property type="entry name" value="3-DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24621">
        <property type="entry name" value="DHQS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-dehydroquinate synthase N-terminal" evidence="7">
        <location>
            <begin position="85"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="3-dehydroquinate synthase C-terminal" evidence="8">
        <location>
            <begin position="195"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8095012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="466" mass="50899" checksum="5C0A3FE1A7AB298C" modified="2025-10-08" version="1">MSDLKANVSETKAGFHVEGYEKIEYDFTFVDGVFDVANPGLADCYKKWGRVLAVTDKNVFSMYGKKMERYFEHYGLTLKVHQTAIGEKAKTIDTYLSICDSMTEFGIIRKEPVLVVGGGLVTDVAGFACASYRRNTNFIRVPTTVIGLIDASVSIKVAVNYGNYKNRLGAYHAPTHTFLDFTFLRTLPVAQVRNGFAELIKISSCSHLQVFDLLDKFCEQLIEHKFGRGDGATRELKTAADIINREAIYEMLKLESPNLHEIGLDRVIAYDPLRHGHAISIDMAFTATLAKKRGLLSGAEHARLLTLFSRAGLSIDHPLFDNDVLDKGTAAILKTRDGLLRLAVPNPLGSCSFLNDVSVEELQEALRLHKEACKTYPREGAGLEAYVDSSDTGYTDNATEELGVEAAAKQAGVISESRGVTNGKTTNGHTNGHTNGHTNGNDSLLEKAKNGINGVLNGSNGIKVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTA0</accession>
    <name>A0ABR1UTA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660758.1">
        <property type="nucleotide sequence ID" value="XM_066818570.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051630"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF14">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="470" mass="49937" checksum="0FA508AADB87ACBA" modified="2025-10-08" version="1">MGMTLASRVKKQFMALPFGDDQQLAGILGLAQRRGSHEQAAVDAAPDESSATNPIPYASTGQGAQRSRSPPRTQPALPSTPPTHQHCRTPATATGSSAPSTTSPWPRALHSPGSHAPDVRACFAVHVPILALSHPPLWSEMVALGALHLLSDEKGHQKDPGLVACREAALDAALRTYRPVLGELGPHNADAAGFTAIFLLIDSFATLREAQHQHQQAAVGVGDVEGEKAGQDDDAYTPPMHWLRIVRGARAVLEAALAMAVVQKQGQASAAASGGNDENGTTTTDTTMSILTIIDSYPRVHYETARAAAAAATSVTWSEEPPDLGTNKNDDNPLTHLMVPLPDEPKQPTEVIAAYAGAVQQLNLIRTAIAASAATPSAGEAVDDENRQKNDDDGKELLFLCRGMMAFPCLVPPLFLDLVEERAPRALAVLAHYFALVARIRDIWWVGDTPAREVRAIRRALRGGRGTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUC3</accession>
    <name>A0ABR1UUC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014619</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661121.1">
        <property type="nucleotide sequence ID" value="XM_066818933.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051993"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013893">
        <property type="entry name" value="RNase_P_Rpp40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15396">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15396:SF1">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08584">
        <property type="entry name" value="Ribonuc_P_40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="334" mass="37276" checksum="DF1421F29DF7ED55" modified="2025-10-08" version="1">MLSLPEPTVYQSSKCFTTYGTMSYPDPKQLPSKGKPWSVLLSQDFIHKVDVIVPAESVDRIKEKLSNGTFAPKYSRVIMTLGEILNGEFFTQYIKIGVANVFTLKNGQLKMYLDKETYERAGLVGQPHGVKGKRGLKPRWVVEYDLRSPASFPGKKGFDRLVYACKKVFNQPLTWLFLNLSQNPLASFAPVKYTSSPFVTEDRHTLIPVITPPQSCLGKGGKLDLEEFATDIYEWLSLVRLDSPRITAGDKIDPYLSRYSVPNAQGDPKPVTLCKVSWQGFIDPNWARQVLVDLIISTSSRSWFAMSTSSFEKGVAGKGGDCMVLRPANSPANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUD0</accession>
    <name>A0ABR1UUD0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014633</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661135.1">
        <property type="nucleotide sequence ID" value="XM_066818947.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052007"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="108" mass="12019" checksum="0F45B2531A353CA3" modified="2025-10-08" version="1">MASVILYWCIDVRVHKAVCISQSQGTIYRCNEVEMVHNKGLGYSSSDLTPEEIAAKLQTQQESEIALDILTNCTLGFVKLSALFSTVGYSAPLRNEAFSTSSYGYRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUL9</accession>
    <name>A0ABR1UUL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014709</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661211.1">
        <property type="nucleotide sequence ID" value="XM_066819023.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052083"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="68" mass="7344" checksum="4B07655DD048FC3D" modified="2025-10-08" version="1">MALGVFRQIAVRQRTKNLGSSLGKLTEALERISPGPTVLDNASEHFGALCNGAATTRQLYPDFHNFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUQ6</accession>
    <name>A0ABR1UUQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661254.1">
        <property type="nucleotide sequence ID" value="XM_066819066.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052126"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="117" mass="13496" checksum="C830E456D0895040" modified="2025-10-08" version="1">MDSEVLQNIDLFPTANSKSFIDNSSNCLRQLSSISFWDNFDNGLPQQQTVNHPLSPPRHRAQDEKRFIKPASRQEGDIIQVFQNLQVRIQGPEREEVIKAQARLLSARLHRLLASFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV22</accession>
    <name>A0ABR1UV22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7888 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661373.1">
        <property type="nucleotide sequence ID" value="XM_066819185.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052245"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057210">
        <property type="entry name" value="DUF7888"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40845">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40845:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25411">
        <property type="entry name" value="DUF7888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7888" evidence="2">
        <location>
            <begin position="63"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="199" mass="21462" checksum="804C9D1698519F66" modified="2025-10-08" version="1">MQISSALLSPPPSAPPWCLAPQSSPEHPATEPSSASQSSNGITQGLEPVKKRDIEERQVTAAVVTILGIVGSAALEQLTSRAVDAAIDLVKDISEWNKAREEFTKATVKGMMDANPDPANLVAAACYNMQYKLETPANVDSTASLEFKLGALKTNFDCMYIKGPNNFYTEGDNGYVNLAYDYLTDRCTFDKSTGDLTCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVD3</accession>
    <name>A0ABR1UVD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661493.1">
        <property type="nucleotide sequence ID" value="XM_066819305.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052365"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="118" mass="13917" checksum="41E7106AB198884D" modified="2025-10-08" version="1">MGPFGRVREDMRDSIRPLFFRYKEGSGGVEIIPLVKTVKVSEEYWSRHGRIWSQLKGFEIHFLRPSETSCLLDEPAAKHRVWLEFVGLTLWSVFAPHYFMDKDGINGYLTDRQDDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVH5</accession>
    <name>A0ABR1UVH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 monooxygenase oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014173</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660675.1">
        <property type="nucleotide sequence ID" value="XM_066818487.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051547"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="551" mass="61565" checksum="00CCEA1CE1A4844C" modified="2025-10-08" version="1">MSTKTFHLLGEDVSTAREIDVPATIGEDELRQLVASYFAIVDSKGVGFVSQDAALATTADVIEAEGPIAISVDGKAVREVPGPKGLPYIGNYFEVYPDHLGNHQRLFERYGPFIKTCNMGSTVYHTNDPALSQIVFSESEFFTKNIIAGHPLHPIKNKESGVFLGDTDTEEWRLTHKFLPPALGPKAVRHYAPTMQKTVEDAFKVFDELDGRDEAWNVYPYMLKLGSQAVGKLVLGMDFKHFEAVDAPLHAMVMRIAQSLELNKKITSMGSWYASMPFGAPAQLKAARTHIESMINQSIADASKGVEDLELQEAAVKAENMVDYVLRATDSKGNKLPIEKIREPLVVATGAGFTTTSSLLSWLLYGLVAYPGMQERILQELIDNDVDEDTAITPELTQKLTFLDAYIKETQRKHNPSYQPARTSKVDMILPGGYKLPKDSIVIPAIHHIHNNPAIWDNPAHFDPDRWSSEAVKNRPTASYIPFATGPRMCIGFNFALQEVKVFLPKLVYRYRFSKASDVSVDYDPMFQLIRPTNLYVRAEKRVKWPPRSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2M0</accession>
    <name>A0ABR1V2M0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662194.1">
        <property type="nucleotide sequence ID" value="XM_066816502.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049562"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19177">
        <property type="entry name" value="SET_SETD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044429">
        <property type="entry name" value="SETD4_SET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF137">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="19"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="373" mass="41496" checksum="9998D6EA30083E0C" modified="2025-10-08" version="1">MGEIDDFVRLAQRQGVQLNGIEPARIPGRGIGVVATRTLKPGEAILEVPMQAVRSLHSISEAVSSQLPAGVSFHGVLAADLALDKTAYLAAWRKLLPTEKDLTASMPLMWPEELQALLPKAARDIVQKQDDKFRRHWSKVSKAFPSLTEEEYMYFWLLVNTRTFYLETPELEVFPWEDRLALLPVADLFNHAADQGCHVAYSATEYTITARRQYEAGEEVFASYGDHSNDFLLGEYGFVMDENKWDFVCLDEVILPRLTRAQKRELEASGHAGPYMLAADSGPSRHLVAVLQKLAPSGENSPGSYDDTDKSLELGAAAKELLKELLGEALANTQGVRGKIPGLRAGQSTQRDMLYHRWEQIESILLKSIGSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3F4</accession>
    <name>A0ABR1V3F4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012462</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662468.1">
        <property type="nucleotide sequence ID" value="XM_066816776.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049836"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="63" mass="7107" checksum="55720C71FBF65560" modified="2025-10-08" version="1">MGARGYDPRTSPWDRGPSQRRSRGPWILGWRKMHNTDLVVVAMVALARAALGVASMGHDDWWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3M4</accession>
    <name>A0ABR1V3M4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662521.1">
        <property type="nucleotide sequence ID" value="XM_066816829.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049889"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="372" mass="42692" checksum="C4CC9F646D27310E" modified="2025-10-08" version="1">MANIAIAQPGASHSPSASFHQFPILPPELRFIIWEQAYLEIVKEGPQNWELLLRDAKDGGAVVTKRDRSNTPFVAGPLRDQYIINLRMASREANCCFTTYILMKVFTPAPYMVEPWKRYTLGRMAMTRVWLCPEADEWIFNFEFNMRHSGHLPLFDDWMSELEEENNSRTLHNSLVVLGSIGHLRMGFWALAGYTEHNIDQFLDSLPQLSRLSIHLEPIPCNDVPYIFDSMMPKLQGGDFSYENRHFAAHCFFQEVGHVEFSGGKVAVPESATKDIQVPDEQVLASKDYEFLRRCVRVELEYAAYPTYRPTGLNRGDIQNLIGRWVTLGDRGVERVMATRITSVQRQFGQFPKLKPVEPKPSGWNKLRCTMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V424</accession>
    <name>A0ABR1V424_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662692.1">
        <property type="nucleotide sequence ID" value="XM_066817000.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050060"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="98" mass="9980" checksum="01D1014B634DF3CA" modified="2025-10-08" version="1">MWTRESSSRDGSYLGDVEAVAVAVAVAGAGTGVEASTLDLTLELGVCGGLALVSAAAAKAEAEGSRDELSLSTADLWRSFPAADLRDAMDYAMKAVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4G1</accession>
    <name>A0ABR1V4G1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662826.1">
        <property type="nucleotide sequence ID" value="XM_066817134.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050194"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="52"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="502" mass="54159" checksum="D3B9A1EA67B863CA" modified="2025-10-08" version="1">MTCSQLPANEATGAAPGTDSTCNLLEAAGFQVLRPNTAEYNAREAEYYSVSAQMSPSCIVQPKIAQEVSKLMKLLVTNTTSNWAVRCGGHTAWGPAADIHDGVTIDLGLMNQTEYDAETQTAKIQGGSLWKDVYSTLEPYGVTVPGGRTSTVGVGGFILGGGNNFYSGHVGFACDNVVNYEIVLANGDLVNANANENADLWKALKGGSSNFGIVTRFDMRAFAAGDLYGGLITHPLSATDRVISALSHFVDGAADYQAGSAFAFWSYIRGASESVIISALHDATGTADAPAFAEYAAIEPRLSSSLRKDSHLNMTIELNFEKGFRNVWFAQTVVNDPAILKFIIEEHNTFVESWKAEVGNDTFSLYTPFQPLPAVLFAHGAAQGGGNVLGMNVTSMRGRNCVLHQAFLVFEGGPELEAEARRRMTGYREAVKRESVRTGTDVAFEYLNYADKAQDPLQSYGADNVAFLRGVAAKYDPEGILRRRMPGGSRYQRMSEYGAVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4U1</accession>
    <name>A0ABR1V4U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(S)-2-haloacid dehalogenase 4A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662965.1">
        <property type="nucleotide sequence ID" value="XM_066817273.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050333"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF4">
        <property type="entry name" value="ACID DEHALOGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="243" mass="26422" checksum="FFEB05E764384975" modified="2025-10-08" version="1">MTSPNKHVVFDVVGKLPFTESLSTKTAANQGFLSAHLLGTLVDYEAFYSALEVPPRPPACAPTPSAPASSATPGWRPARRSRRRRPRAFATDDDRDFLLGAYAQLRTRPGVEQCFRTLRQAGYTVWALTSGDVARVSGYLRDGGVEILPENFVSCDSIGVGKPAPAVYEHVLEQFPAEGLDAWFAAGHMWDASAARRTGEPGCPRGEKEMCSEIFGDMDVVADSLPEMADRIVAFEEQLAGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5A0</accession>
    <name>A0ABR1V5A0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013120</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SCC4/mau-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663126.1">
        <property type="nucleotide sequence ID" value="XM_066817434.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050494"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019440">
        <property type="entry name" value="MAU2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21394">
        <property type="entry name" value="MAU2 CHROMATID COHESION FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10345">
        <property type="entry name" value="Cohesin_load"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="113"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="172"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="185"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="268"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="985" mass="110851" checksum="F9A3555D6B436A06" modified="2025-10-08" version="1">MTYRGSLPGSGFYNGQNGQQWQQQPMHNGFDAYGNAQSQFPQHHQPGYNQQPQHQPQRQPQPQQQPPPPPPQQQHYAQYQNASFVPIGYPQQSQHQPQPQQQVQSINYAAAHMNPSQGFNPIFDQQSHHPSLLQQQQQRHQQQQQQQQAQYRQQSANYAAQMGQVQGFVQQPRPQQPNVATFSPQMQQQVQIAQQQQQQQHGQAQYQHQQQTQKPPMSWQPMAPPAPPPTQSYQTTPQMNSAKLPVKQEPPQSYSSPQIQHYQPVPSRVNSPHVNSPIMAQSPQYPQQPKQNNGRNGSVSSVAGARMDHAGRVSASPRLHTQGLPRSPSVGSTRSPAPGLLPHQDTNSLLICVAEDMFSAARKGVLHVADSLDSKAVQEYQKLIATGLGCLELVLNSNRLAPRLEARLQLRYASVLCEETNNVMESETALAKGMALCDKYRYGDLKYLMQFLQLKMLSQRKGKAAIKAIDSHVADAELLKHTHWVYVLRLFKASMYLESPNPSDVHAMENLKAIKELALQRKDHIIFVLASLLEGLGLLKHAKDDSVARIQECIAQCLQYQLDESVHIPQVDILLLMLDFACSLHQQSPGLIAQKLRLLQRRVDESLKDNSWSLSDTQVLLPIKKQAANRQVISADTLAVIRPGQEGDTCDYLVMSFWSKLEAFVMTYTYSGLGTLYDQRRTDMKVYEFWDEALNQLEKNSHKMRSIPTSLQEAIRCAEWRRELKCYIQILRGLHLATQSRWREVGECVSQLETLVQPSAAGSIEGIVGVYTYYLGGVYRQGIGHLDMANSIYQHPVLSTNTEGSFQGTGKQAESDVRLLAAFNRIWIMQHEDHRDDRQTSELLEQLRPLCKRHPNQHIRTVWHIVSAAIQTEPALPMTELKSHLSSALNGAKALGDVLSLSIALNLMRAKLFHDVVGDQALKSAKAGAMQAKRSHNLLWMSVAEGLLAQSYEVQQQHGEAQASWDLAKDYASQAFKQSDTALEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5P0</accession>
    <name>A0ABR1V5P0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663280.1">
        <property type="nucleotide sequence ID" value="XM_066817588.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050648"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021122">
        <property type="entry name" value="RNA_ligase_dom_REL/Rnl2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21189">
        <property type="entry name" value="PHA02142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09414">
        <property type="entry name" value="RNA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA ligase" evidence="2">
        <location>
            <begin position="224"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="379" mass="42323" checksum="CA903DDFD2166137" modified="2025-10-08" version="1">MTMYVAEIAAINSITDCSEYETAMVGNLPCVVKTGEFKVEEQVMVFPVDTFVFVDTNNAILEYTAHNDVQKDKAGVRGVHVKPIMVQGQVSAGLIVKLARFPDVNAKVQRIIEKSNKDSDTAPTKASAAVRPQSRQSRGFGLKKWTPPDPKSFLGERPAFVPSTTAPMIEESPGIFWDEANWPSIWQATPHMPNRMKMFIYLVQNDSAWAKSIERRPAVGRGVLPHARMGICGEDNDFRDTGKNTMWDSLTRMNVPATLGKLSKSNIAIEGFLFVTRAVMTPNGPRPHNQFRIFAVWDIDEQKRLSFEKTKEFAEWLGLQLVPDLGQWGLSEILMGEAALAELGVVYMSMDGQTVMKSRPAKNAKTVEFERALLKLARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6F9</accession>
    <name>A0ABR1V6F9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663542.1">
        <property type="nucleotide sequence ID" value="XM_066817850.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050910"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="120"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="294" mass="32525" checksum="60DDB22FE52AA1D1" modified="2025-10-08" version="1">MAISGVDGWMQASLADFFSMRPKPSQKELDGYATSLVQGSTIHPVGMQGSLSYTVVAVRAGRKIIVSFRMPGSKLGGRIEKAAQNVHGKLVPVATFHGTVSSQTAYYEPLKKLTLLEDARAYEFLRNTLTQLRGPQGIACLYSGSWPQVVTHGDLSQTNILVDPETLSITGLVDWSLATVAPFGLELSTLRRMSGSMFSDGWTDHPFRPQTEAAFWTEFWRCTGIEDTHERERVRKMAELSCKLGVILRYAFCNTLGGVALDQVVPKPAQYLRSWLGHQAWSDLIIKDSPEPMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6G3</accession>
    <name>A0ABR1V6G3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_013512</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663518.1">
        <property type="nucleotide sequence ID" value="XM_066817826.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050886"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF4">
        <property type="entry name" value="URIDINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="5">
        <location>
            <begin position="44"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="335" mass="36894" checksum="509E42F546E15AD5" modified="2025-10-08" version="1">MAPTDGVGTQAAVDADDWPLTNNDGNKATVNAYEMPNVDNRIKVIVDTDIGTDPDDGLALAYLALHPRCNLLGVTIVTGDVQKRAAVAQVLLRACGPNAAEIPIHCGRRDPILEGEGQPNCQQYSDIQKEAHVLNRLENTAVDFMRRTIHENLNEVVLLTIGPLSNLGLLFALEPEIASATRGVVSMAGKFLPAGDRHKEWNMSVDRTAAGMVLGARRPSHRFVGLDVTRQVMWTKKEYLEFEGQVQGPLKPVLQKLSKWWLSIKPRMTFHDPLAAAVIFEPGLCKWKSGRVVIDPRNAMITFTESEGGPDLIASEVDADAFFKHYLDILRDVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6L9</accession>
    <name>A0ABR1V6L9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663609.1">
        <property type="nucleotide sequence ID" value="XM_066817917.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050977"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="101" mass="11403" checksum="BEBB068459F4D4A0" modified="2025-10-08" version="1">MSRDQQPILSTAHRDHRPVSKQTLAANDHGKPESDRVAPSAAQRHLPHQQLQSSRGLGPVQVQRRDDRKREDIRADARDAPARGGESAYEREPDRLVRALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6T9</accession>
    <name>A0ABR1V6T9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013660</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663666.1">
        <property type="nucleotide sequence ID" value="XM_066817974.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051034"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="30"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="330" mass="36123" checksum="E7AF29F987127C9F" modified="2025-10-08" version="1">MTNAEEVHKQHLTVGIMTTCLALATASFALRIYARLSTAAKIWYDDWWMSVVMVISIAMSTSIFLGLAYGSGIHQQYLAEETVQSFKMNLYVYMILWSFGVFAVKVGILLFYWRVFTIQYFRRSVLAVGVLSTAILLVNFFTFTFQCWPIARFWDESIAEGGCIAQTEFYLASAIINVVGDVVVLVLPLPVVWSLHVAEQEVVAELPVPTRVCVASIFRILAVQEINPKDFTFTNVGGGLWSTVEVEVGFICANLPSIRPLVFRCLGYRTGATSSGENDYSTPAAGRYYAKSGLGASRSGGGGGAFKTIGSKSFTTTTGGSISKPFRDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6W9</accession>
    <name>A0ABR1V6W9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell division cycle protein 123</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662819.1">
        <property type="nucleotide sequence ID" value="XM_066817127.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050187"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="347"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="50612" checksum="F7B4E40FC420B0F5" modified="2025-10-08" version="1">MPDATGTTTSSGANRSPDAAAHLEFPPITRDHILHCSYDYWFPKYRTSCIKSRIIPLTPEFIEYITEDGIVLGDEDDEEGQDEDDDDVEWESGPTNLSTAQTRSRYEQAPDESDSDSDDDEPERLPPNKRFPALHQTIKDTIAELDGAVAPKLNWTAPKDAAWISTHQNTIKCTTPNDVYLLLKSSNFITYDLEHAFDDCTPVAGSNGSTTTTTTEAPGSSSPSPPQHQFKPVLVLRSFFNPHTALEFRCFVKHRYLVGITQRDLNFYEFLQGLRPALVAKISQFFNHKLRYTFPDGSFVFDVYIPEGEGEPLGRVRLIDINAWAPHTDSLLFGWHELNEWSVPSGPMLGTASAAEEEQSETARDGAVSDESDTTDEDDEDEEDDVVPELRLIDKEDPAAYNFSSPAYSAHKLPKDVVDASLAGEGGMREFAQKWKEMTEYRGDIASGEEKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7W7</accession>
    <name>A0ABR1V7W7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014046</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664052.1">
        <property type="nucleotide sequence ID" value="XM_066818360.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051420"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF20">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14670)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="525" mass="58417" checksum="8806B8A87901EE49" modified="2025-10-08" version="1">MTDNIKRPEAVAEHLDKRQHLLPDKLPLPVELAHLSSDEQHHLDRHLTKTLDMTLMPVVFILFLLNILDRNNIASAKISGLTTTLGITNSEYNTCLLMFYIGYLDIYQRKQVPSNMIIGKVRPSLYICLMTSLWGILSMSQGFTKTFSQLAAVRFILGLVEAPFIPAVFVLGMSGGRMGCWYTRAELPPRIAILYGGNMIATAFSGLIAAGITSRMDGAAGRPAWEWLFIIEGSLTVVIAILLLPLLTDYPLQSKHLFLSRELQLYAEYRVRKENAGIVDEDPESIWRGLRQALVDPKLYMFVVMQMALITAQSFSIFFPSIVGTLGYDREKTLLLTSPPYFFAFFVSLAVSFHAAHAHERGYHIAVPMLFALLGNLLAMFVPSTGGRYFSMFLMTAGSYSPYNLVMSWVSASLPRPRAKRAAALAIVNFMSAGVSHFYTSYMFPDSQKPRYYAGGAVMSGACLVCAPTAWVIKRHLRQQNARFDKEEEKASRGGVRGGTVAYDRIQGSGVGRSGDAVVAFRYVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7X9</accession>
    <name>A0ABR1V7X9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664054.1">
        <property type="nucleotide sequence ID" value="XM_066818362.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051422"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="280" mass="32368" checksum="524094A87325328A" modified="2025-10-08" version="1">MPKQPNIHTHLLAHSKTQNTPLTIRRMTPKLLIRNPPARLRNPHAPKHHLILHSGRSRRLLRRQRVLDPALRPCARHGRQRRRPRRRRHHPLSHPRRGFHGLDPAQLHHGRDAVPAAEREAADVEPERLRALVVPVEALDHLRGLEAGRVGGPAGPAAGQDRLLGQLAEGVVPERVAEHPQQRRAELGPGRVRVRRHGQEVHELRRRALRVRPRRRLVQQPVDRRQLAVELRRDRVERAAELEHAQAVGRFHQLLLPLLHHEVVDLLLRHAMQEDDTRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8U7</accession>
    <name>A0ABR1V8U7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663146.1">
        <property type="nucleotide sequence ID" value="XM_066817454.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050514"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022085">
        <property type="entry name" value="OpdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053204">
        <property type="entry name" value="Oxopyrrolidines_Biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12311">
        <property type="entry name" value="DUF3632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="293" mass="33016" checksum="7E8EF614BA5FDCE9" modified="2025-10-08" version="1">MADFTAQMQRIEKRLDEYLGGQPSAEAPASIAQTIAKDFPTAEDDVESYLGPLWQSVTKLAQGASYDHPAQDKLVNMVSEVMLLPDDQEIRIWGDVSNYTLPHTLTRSKISQADGRHMKEAKWKELPLLGAEFREQINGPESADDETEQAKITQSWINFHAFAARLNGKGVTNWWDIPLWMLRQGLEEDLSSAPKLHDCHIMTAAEIVEHSGAIMLASKVIPTEELDDTEKRMFAPGSLFKGEAGYTPERWTFWARRLREEAAKCSSDEVKNAALRAARLMEVWLDRSTAGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGU2</accession>
    <name>A0ABR1VGU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_010657</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664262.1">
        <property type="nucleotide sequence ID" value="XM_066814972.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048032"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01729">
        <property type="entry name" value="LSm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017132">
        <property type="entry name" value="Lsm7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF5">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="52"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="10"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8070454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="141" mass="14798" checksum="36C3DA75DB65964F" modified="2025-10-08" version="1">MADRPHQRGGRGGGGYRGRGGGGGRGGHGAGGRGGHGGGAEGGQERERPKKENILDLSKYMDKRITVKFNGGRECTGTLKGYDALMNLVLDEVQEVVRDDEGNESSRPLGLVVARGTLLVVISPVDGSEEIENPFAQPEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGZ6</accession>
    <name>A0ABR1VGZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA dehydrogenase mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664293.1">
        <property type="nucleotide sequence ID" value="XM_066815003.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048063"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37844">
        <property type="entry name" value="SER/THR PROTEIN PHOSPHATASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_1G14840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37844:SF2">
        <property type="entry name" value="SER_THR PROTEIN PHOSPHATASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_1G14840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="286" mass="31675" checksum="54C85E802770BF8B" modified="2025-10-08" version="1">MVKIQIQSDLHLEAPKTYDIFEIVPKAPYLALLGDIGCLAKDYAEYTQFLLAQLRNFKAVLLALGNHEPYHSSWEEARASMAKFQEDVTARKQAGEQLGTFVLLDQTRFDIDDDEEGHGDGGVTILGCTLYSHVPPKARKDVGLRLNDFNYIEDWGLDEHNAAHASDLAWLNAEVTSLEASSSSGSGPATAPKRRIAVLTHYCPTLDARAQDPRHAGSPIQSGFATDLGGEACWESEVVRLWAFGHTHYNCDFVDEERHGKRIYTNQRGYSFSQSPGFDGTAVVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHT8</accession>
    <name>A0ABR1VHT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664603.1">
        <property type="nucleotide sequence ID" value="XM_066815313.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048373"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="255" mass="24411" checksum="339C8418C77A914B" modified="2025-10-08" version="1">MTVANTSLYKTGGIGTTTTVTASGVGGTATEYITVATTLPGITYTTTAPGGTVTVPTTISVSGGGGGSNATEYVTQTITTGGGVATTTVTGPGVTSIITASGIGSTATTTVTGPGVTSIITASGVGSTATEYVTVATTLPGITYTTTAPGGTVTVPTTISVSGGGSTATTTVTESGGTVTVTTTGGYGYSSSCPIVTPPAPTTVTVTTTTGTKCDGGGGGYPTSPPPPPPTTTPPPPPPPVTTSETTPHHRLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIF5</accession>
    <name>A0ABR1VIF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664829.1">
        <property type="nucleotide sequence ID" value="XM_066815539.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048599"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="441" mass="49581" checksum="16E48ADE656DF886" modified="2025-10-08" version="1">MALQLPHEVRGIAAGVLVYSFAGLMCSLLFVWLTWTHRGENKPLYIWLDVALIGYLLLASTATAVVTQLHTFVSWEDVATAQWEEAVAHPKSPEQIISNGAVGIDLGLWYFRTFLFSPSAYAFLLTICAGQYAFSASAMLVLFWAFALLQSIHGWTEKPQIKVTLNRINAAGKGTSIVLPIITICLLQVKSVQKSVVAFMFLANVVLMISLAGGCGFMLAILLRYIQSRRQLLGWDVQYGAASGSFGFSASMSQSQGQKRRGASRSTYDRWLMTRFSIAFVILSIFELSNMLFQFTGMQNSNKDALRSSPDISVERAKETAVLFLPGPAPSFLIFIVFGTTAPFRKHMYRTFVSKCWQRQEVERKRTVPRQGSQHAAAPNTQNAMPTLPQERAVPLYRPMMIPQKREFPLRDLERGVPSSQRPRRMTNGRYYQYNDRGIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIQ4</accession>
    <name>A0ABR1VIQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional coactivator HFI1/ADA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011303</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664908.1">
        <property type="nucleotide sequence ID" value="XM_066815618.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048678"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024738">
        <property type="entry name" value="Hfi1/Tada1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12767">
        <property type="entry name" value="SAGA-Tad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="49715" checksum="9FA9F5D67BFFA5A1" modified="2025-10-08" version="1">MPDIDPAALSRPSVHLTTPTLKSITVQTQSAQKVTKTSQIIPARIDLEPLYTALKAAIGPEQWTIYKDSTTQFILGRLNQAEYSERIDPFLISPNGEKEHLHNQLIAAIYGNLTREMPDQGLAPWVSANDKPTTGVGAKPVTGDAAERRLKGEVMQLPSRDRRRIKDLVHNDFDPFESMAQMFSDHHRGKAVKAPEPPASAAGGINKTMNLDLEIRKRYAQPLAVESGEFPDVASIESKMLPFCFQAGLTNGHASDAAHYVTHATEFFIKELLSSVLAKTRSNGPGESNSAGFGAGPGWVQTHKYKRQLRREEEALMRGELSRDKAGLLPVEAKAAGDRPPLGMADLRLALEIGDCGMGSFPIATKSVLYGYREGELEHWDDYSWVDDRKPPESMDIDMDGVTNTNPSNHALTNGVLHSEPMDVDEQWGWEGTDSTDLMSLDNVLDSCLAVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTR9</accession>
    <name>A0ABR1VTR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009319</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665596.1">
        <property type="nucleotide sequence ID" value="XM_066813634.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046694"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF53">
        <property type="entry name" value="CHORION TRANSCRIPTION FACTOR CF2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="526"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="552"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="70"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="180"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="240"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="366"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="469"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8074656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="629" mass="68935" checksum="B7A26CE99AE34149" modified="2025-10-08" version="1">MAPTLSLRAAVAPRSDLSNGAIAGAVVGSVVGGTLVFLVLLFLYFRYKRRRLQAAAEADLNTFKPPIERRVSFPGQTDASQVEQGTSTANGRVEPGAPGLSTGATFTHLPSQTPRQGFGQDPAPGGAASAYYANYPIGEPSAAASYYNMDIAMESDPNLPPMAPPSRQMTELYQEQLKQARELRKKERQSSKGSVMSRVINTLRRKRSSKSSSLASPVEGSPLSRQADVPFFSVEGAEGSAMYSEPQAMGDESGSDLHRAKKTKHDDSYSSAGHPRLDSLNTALKTEPPHDPSLPSSAYHRMDAPAGPFHDTSRFSNERLQSPDIPEPMEGAPYDDANNQALRPSHSPPLQSDSFIAPIDIFQPSNDAEKAAHTHAELERYEKSSSPTYMGGSSSPPNFAGTRTDNGPVEVEDEVIDDYSEDEDEDDTQMQLDQTAYLGGNPTYAGDNGQNFTNNPNRVTPDHRLTPSVDYSTPGQSSSNPSAGVTPDTRITASPSSTENIFIKQENSTSPESYGAVPSPQTPQSYTCDECHRAFDQLHKLNHHKRYHDRKHECPYPNCDKRFGTKTHLDRHINDKHEKKKGFHCPEVGCPYFKGGKAFPRKDNWRRHMQNKHNITPTIDPEAMDQTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTW0</accession>
    <name>A0ABR1VTW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fumarate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009358</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665635.1">
        <property type="nucleotide sequence ID" value="XM_066813673.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046733"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF1">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="544"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="492"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="502"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8074695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="628" mass="67722" checksum="96CDFDAA21839FBD" modified="2025-10-08" version="1">MAAITVVGGGLSGLSAAHTIYLAGGNVVVLDKQGFFGGNSTKATSGINGALTRTQVDNKIADSVKQFYDDTLKSARDKARPDLIKVLTYKSAAAVEWLQDVFNLDLTLVSRLGGHSQPRTHRGHDAKFPGMAITYALMQRLEELAETEPERVKIIKKARVTSLNKEGNKVTGVTYEHDGESATLDGPVILATGGYAADFSESSLLKKHRPDTYGLATTNGTHATGDGQKMVMAIGGNGIDMDKVQVHPTGLVDPKDPGSKWKFLAAEALRGEGGLLLNADGDRFCDELGHRDYVSGMMWKEKEKNKFPIRLILNSKASNVLDFHTRHYSGRGLMKKMTGKELAKEIGCSPDHLQKTFTTYNAIADGKQKDPWGKKFFHNGPLDINDDFHVSLMEPVLHFTMGGIEINDKAQVLNQQQQPFEGLFACGELAGGVHGANRLGGSSLLGCVVYGRVAGDTASNYLFQQALSGATGGAASRLGQISLHIDPSQPGRLSVQWGGDASSASASTLGQTTSAAGPTPKADAGKSSQTASKAQNPKKFEIPQKEFTMEEVAKHNKKEDLWVVVKGVVMDLSNWLDEHPGGPQAIMNFMGRDATEEFEMLHDDEVIPKYAPQQVIGRVKGQEPTLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUI1</accession>
    <name>A0ABR1VUI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBX domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009573</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Directly interacts with VCP. Interacts with UBQLN1. Forms a complex with VCP and UBQLN1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665850.1">
        <property type="nucleotide sequence ID" value="XM_066813888.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046948"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46424">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46424:SF1">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23187">
        <property type="entry name" value="UBX7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0834">Unfolded protein response</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="8">
        <location>
            <begin position="296"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="425"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8074910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="482" mass="52942" checksum="8EB4B9619A262661" modified="2025-10-08" version="1">MFFSGSLQEGISRALEQTKNVVCFVTDEGDESQQWEEFLAEPTVKAALDSHAVSLRLKAGSEEAGYLEALFPVPRKPTLIIIQNGQLREYIASGTSKDEFTKRLRSALGSSSQTVPTGSAPASSSAPQNPSQPATGTGGDLYDDNPPLVHGNDDDLYDAPPPVASTSQQPPAAAPVSGVPTRLEAEKQAKEKAAKAEREKRAKERQEAANNGSEGQSSNATAAMSTYAQMMRKKRQEAKEERQRILRRIEDDKRERREREAQEKQARLLLAAIDPDAAASSSNPAAGPPIPLPTRGGGPTCNLQVRLFDGSTLRGRFPSDQTLDKEVRQWIDENRADGTDPYTFRVVLTPLPNKAIEPAEESEMLRDIGLAPSATLVLVPVIRVATAYEQGGGLLLRGWSYLYALIAMLFSPFAVLFRGRNNANHDTSHENMPMDDLDADGSSRQRFRGFRNPEDERRDQQLYNGNSLNFEPRKDDDDESDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUT7</accession>
    <name>A0ABR1VUT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665949.1">
        <property type="nucleotide sequence ID" value="XM_066813987.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047047"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="81" mass="8922" checksum="3FE0F17F0D11656C" modified="2025-10-08" version="1">MGVLYWYRNERYAAGNFGTTLTAIIVSLRFGRALPTGKMRLRRAQAGRRGERQSPAAPVAQQAEVPDHDDPFNAACGSLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVU8</accession>
    <name>A0ABR1VVU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666315.1">
        <property type="nucleotide sequence ID" value="XM_066814353.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047413"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="129" mass="14742" checksum="FFA381D8681ADC70" modified="2025-10-08" version="1">MQDCHMQYVSDDPDSQGSALERFSDHIARGAATRGYDLRKAQYYKQWLIDAGFTEVQEIFYKIPCSQWPTEPKDHRIGEYQQRNGLDGLRGSSYLMLRNAGLSPDEVEALISDAKHELRAQTVKAYSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWL0</accession>
    <name>A0ABR1VWL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc homeostasis factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665631.1">
        <property type="nucleotide sequence ID" value="XM_066813669.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046729"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="116" mass="13108" checksum="0C9392C7938359E4" modified="2025-10-08" version="1">MHVQVAFPITEEGGKKYMKLAKSARKCLHEYGIHSATIQPEFCLDETCNHLDVSMTTDVRRVFLNAWMIVWDRDAALYPPSQNGDAGSHKSGHSGHSHSNGHDHGHDHEHGHEHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX54</accession>
    <name>A0ABR1VX54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665358.1">
        <property type="nucleotide sequence ID" value="XM_066813396.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046456"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01443">
        <property type="entry name" value="Cdc25_Acr2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF50">
        <property type="entry name" value="REDUCTASE (ARC2), PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13400)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="37"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="156" mass="17327" checksum="A10EA70172BD6B0A" modified="2025-10-08" version="1">MATLAQAPWHAAYPAPKTTAPGALTKEDVLGMLQRGEEEEFVLIDLRRNDHEGGTIRGSINLPAQSLYPTIPRLYKLFKNAGVKKAIWYCGSSGGRGTRAAGWFQDYLDEKGDKEMESAILKGGIKGWAMAGDEFVQWMDEYDEAVWRALKEGQCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX80</accession>
    <name>A0ABR1VX80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrogen permease regulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NPR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666773.1">
        <property type="nucleotide sequence ID" value="XM_066814811.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047871"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009348">
        <property type="entry name" value="NPR2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991:SF10">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991">
        <property type="entry name" value="NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06218">
        <property type="entry name" value="NPR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="144" mass="16022" checksum="62294FB09C998CCE" modified="2025-10-08" version="1">MRTKIVAQSPPGCIVATTFGPHLKPPLVDFDIIQEYIIPRKAFFNRFLTVNTPDNKYSILGYPVSIPHERYHRNEFIFNFGLVVESDCDFCPTRSSSAASPSPSPRWSARTATSAPRARSTTGGGRLRACWRLSRRTSTTTASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXC8</accession>
    <name>A0ABR1VXC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009654</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665931.1">
        <property type="nucleotide sequence ID" value="XM_066813969.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047029"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018450">
        <property type="entry name" value="Romo1/Mgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525:SF1">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10247">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01378">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8074991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="144" mass="15609" checksum="305858B40918EA38" modified="2025-10-08" version="1">MPVPVGHGPAAGPSALDKMKMGGMMGGTVGVIIGFIFGTVNIFRYGAGANGIMRTLGQYMAGSGATFGFFMGIGSVIRSDASPIANEAFLRAQRRPYIMAAQKAYRPRELLREVRAIMPFEIARQLDWPCTPNDMYHDEVYDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYK4</accession>
    <name>A0ABR1VYK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DUF221-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_009923</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666200.1">
        <property type="nucleotide sequence ID" value="XM_066814238.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047298"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022257">
        <property type="entry name" value="PHM7_ext"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF26">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G10920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12621">
        <property type="entry name" value="PHM7_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="585"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="632"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="664"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="33"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="205"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="8">
        <location>
            <begin position="401"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="10TM putative phosphate transporter extracellular tail" evidence="9">
        <location>
            <begin position="746"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8075260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="856" mass="95723" checksum="58A4EF85AF121F80" modified="2025-10-08" version="1">MGSYSIAGPAEALAQGSFNTMEKKPQGSASLAAVVSAFVPTWATGLFFVAIFIMIRHRYRNIYMPRTFMGTIPEKSRSPAPSGAWFDWVHTMWDVPDKFVLYRQSLDSYLFLRFLRTVIFICLVGCALTWPILMPVNATGGGTSTQLDSITIGNVKDKKRLYSHAIVAWVFFSFVMFTVARERLWLIGLRQAWTLSKANASRLSSRTVLYLSAPRDALEDSNMHRFFGDGAVRIWPATNTEALESLVASRNSKIEQLESAEMSLIRKADEKGRSIAKRNGTETASFSELSDEVKASFRPKRHLKSGRKVDSTRWLREQVKETESDIDEARNAHEIGHPQGAAAVFVEFKTQADAQRASQQVASANLLALTPRHTDIPPNEIIWKNLTIPPTRRASQEGLAIAIVITTIVFWSIPSGFVGLISNIGYLAENVEWLGFLKRLPKPVIGLLSGLIPPLVTSALSKYVPNIFRYIFKSFGSPTTTVNELKVQKWFYIFQVTQLLDKLKDPTSIPILLARELPKSSNFYLTYFIIQGTTTAADNLLNYSDLLTYLIYDRIFDKTPRQKFTRFTSMKGIAWGKVFPKFANFTIIAIAYSCISPLVMGFAAIGLSLYYFSYRYNLIFVIQPKVDTKGQAYTLALQHLLTGVYIAELALIGIFGLRQATGPSVLVAVLFIATIVYNALMNKYLAPLENYLPADLVSNPDSNDETTPLLSSAEEGHAQSHIQRLGERAHVSPKVAEHVVDPIARFFEPRISTSYQALKHWLNDDESSDGITTSAPPEYSEQDLGKAYLNPALTSPTPLVWLAKDHIGATANEIRENEGKGLKATDQGAWLDDKGRVRWSVDDVAEVPIWKEKIMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYS3</accession>
    <name>A0ABR1VYS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009983</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666260.1">
        <property type="nucleotide sequence ID" value="XM_066814298.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047358"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="7"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8075320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="392" mass="41464" checksum="11057FE9D7A5E7FA" modified="2025-10-08" version="1">MATPEKNIVVLGGSYGGISAAHSILKHTFPHLPNKETYQVVMISAASQAMCRPGCPRALISDDLLDQSRFFVDIQPQFEQFPKDSFRFVQGTAVELDHESRTVTYRPAAGQPETISFYALVIATGSSTPSPMFSFNQDETSLRASWSAFRQALPTTRSIVVAGGGPTAVEVAGELGEFLNGRAGYFSAKLENPKVSITLVTSSTKILPVLRPALAAKAEALLAKLGVTVLKNTRVASVAPEGSGSEADVLATPTTVTLDSGETLEADIYIPAFGITYNTGFIREKDRSSSLTPEGRIHTCSATLRVEKAGPRVYAVGDVASAARPAVHNILAEIPVLSANLKRDLLTDAGVTGAAVAGEDRVFKEDTKETQLVPIGQSKGVGAGGGLRYLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7F1</accession>
    <name>A0ABR1W7F1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">xylan 1,4-beta-xylosidase</fullName>
            <ecNumber evidence="11">3.2.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_007226</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Hydrolysis of (1-&gt;4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini.</text>
            <dbReference type="EC" id="3.2.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.37" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666883.1">
        <property type="nucleotide sequence ID" value="XM_066811541.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044601"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56988">
        <property type="entry name" value="Anthrax protective antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046147268" description="xylan 1,4-beta-xylosidase" evidence="13">
        <location>
            <begin position="17"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="14">
        <location>
            <begin position="473"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1083"/>
            <end position="1112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8079408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1490" mass="166203" checksum="52228BC6EAA10DCC" modified="2025-10-08" version="1">MRWFVTTSCLWWLAAAQLHTQNSNADRRWIGLERGADTPSQKESFLDALLANMTIEDLVLQVHLMFAGEIIGVESKNELYDHTMRFSPGSPIGVMHDWYTLNTTQYNELQQLNLDNSRLKIPLMHTAECLHGVGSFKQSMFPQSLGLSASFDTDLVYRVGRAIAKEARSTGIHACFSPVLDIGQDPRWGRMQEAWGEDKILTSHMGVAYSSGLSKNSSWSEPDAVVPVMKHFAAHGSPQSGRNAAPFMGHGNRQVLQDLLTPFKAAVQLGGAKGVMMAYNEFDDIPAHVHPMLYQALEDWGYDGFVMADDTGMIELETMHNVARSPDDAIAQWFNAGGMLQFYDYSLETYLNTTKGLVANGTVALKTLQSRVRRMLGVKWDLGLFENPFIPKDSPNPLSLVQDHRDLTLEAAQKSIVLLENRNNTLPLRPQEQNINRIALIGPFADTMNYGDYSGAWGQYPAAAAKTLRGGSAGVHELIQQHQDGARFQLGRQHVGIQCSTVERMEVPALDWGMYPPPGLPSNNFSIIWEGELASPVDLDVDGWIGVAVGPNTTAKLYVDDELVMAHGTADQTLFDPGTVMGNIMQYTFTQANSTQPPSGSTPLTFRKGETYRIRIEYQAYNLHKKTENVSSLNSQMILFWNLVGRKGDDAVSQAAELAASADLVVLAVGAAWNSDGESGDRATLGLSPSQDALARAVYATGKPVVLVLQGGRPFAIPEYYASSAAVLSAFFPGQSGGQAIADVLFSKASPGGRMPVTVPRHVGQLPVYYNFKRFARRIKYLDVDSEPLYWFGYGLSYTTFATSEFRASTSPTKALVREQQQQLHNKTIDATVDGNEFTSGDTITFSVNIQNNGTIPGSFVAQVYLLARVSSVVQPVKQLVAFQRVYLEAGETHVARIDLDVDRYLTIYNRWDEWELEKGEYNFSLLAHGGSALETGTFIMENPDFRVISLLLTYYANKYARPWPSIVPNRKASANALVMSWNLLPAELRWQIVSYFELPRLELGGRMPSQEVVDNRAVLCSICRACRCAPEAWALLYRNIVIYTDDEEVASIAPFSSRPTNRLPRGQYGRLRIQRVAHGTAAPNTDAQPGLATPHQVPGLPPVPGRGAASGNEQKPCIVVHNILRQYLSNAATSSSVLPKLTTLQLQVHEVPRPQLKRFQDLTSREIERERSTRRSMVSFDTVCALLTLPTLRHVETWRDDGFESFFDRRDAREPQQQLAQPRPRISHRDWLPQMESLTLSSANFHCGYFYAACEMATNLRHLSLDAIRIEQGHQNSELHSYASLDSALQLRADTLEELCLDGFAHHPIQHLGGGGGPASNGVKRPRGLDCLRHMPKLRSLRVDMQLLFGVSSQVPHVEQPSLLPPNPELPSLLPQNLERLDLRDAWYQFSHDVPELFREDPDQYVEALVEQFQNLAEVVGPQEAQRPLSRLRRVHLRPDAERIRREARYIEYHWLDAEQLGMIEKVLGQVGVVFTYELAPSLDDLEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7V6</accession>
    <name>A0ABR1W7V6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667050.1">
        <property type="nucleotide sequence ID" value="XM_066811708.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044768"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="9861" checksum="E78CA0D4482CF25D" modified="2025-10-08" version="1">MDEAVVRLSRHVRVVGRSDDYAEDLTIQGWAQTCEILTQLGLKPHKDSLECPGVERDGSVSPAVSAEARHDLFETQELGSCFILFANAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W807</accession>
    <name>A0ABR1W807_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007434</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667091.1">
        <property type="nucleotide sequence ID" value="XM_066811749.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044809"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_uS12_bac"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="177" mass="19017" checksum="95F1E71E7EAEDA07" modified="2025-10-08" version="1">MAVPFFRSLMPTLARRPAMTTPSIASKLPAKTIAIRTFSSTPAPQATINQAMRGCHNKGKRARHAVSPALADTRSPQQKGVCLKVGIQRPKKPNSGERKTARVRLSSGRMITAYIPGEGHNIQQHSVVLVRGGRSQDCPGVRYHLVRGALDLGGVANRSTSRSKYGTKKPKKASVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W835</accession>
    <name>A0ABR1W835_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Roadblock/LAMTOR2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667118.1">
        <property type="nucleotide sequence ID" value="XM_066811776.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044836"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="12684" checksum="EE2E6689F69BB49E" modified="2025-10-08" version="1">MAAPVLIPEGLVTAGLDSVALALGVDDKVAVVGDGAGLRQLAEEVEDVSGGNGGQLLLYGVAGRASGAKALADVVAKGPGRLTLLTLGETGTIRVFGDQLVVVGVAVGHGHKALLVLLLGSLEGSTDVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W848</accession>
    <name>A0ABR1W848_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667133.1">
        <property type="nucleotide sequence ID" value="XM_066811791.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044851"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="404" mass="44862" checksum="602CF8F340632F37" modified="2025-10-08" version="1">MAGSIAAQDQGSIEARLQDEVKKLDDAEFHYRAHFKSVIDTYNDASKPVLPYLLEQAQNATQSIDELKKNVAGLRYDLYKASLGALDTAVKEHGRVAIDEPTRNAVLLEILRELDPLFQDGTLAFGRNIIHGYAAQEYFDCPAEPSENLEEEMHDFLDKKMPLLTDNVIPSTLRPQQTDVFGHQGMHFEYKMIYVAMGARSLRAASTNICRSVISIYKGTDSQAAMANLMEPFLTTYTAQQLNLIYQLLNTESAVESVNDIIDLLTSPSVVTANIMLYKLMHSAIVLAKYSCLVTFLTAAAAVSFPRPEEIHPVVKDAIRKSTVADTLKCPKQLLNCFSEMKEQIARGDFSARADDSALQYICGDMSGLALMDGFFASRLKDFASQLPDLDLDLVSFFSSCGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8R7</accession>
    <name>A0ABR1W8R7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamine repeat protein-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667365.1">
        <property type="nucleotide sequence ID" value="XM_066812023.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045083"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="535"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="552" mass="61342" checksum="97002B1C6DDAF579" modified="2025-10-08" version="1">MYSANYNGFPNAGQTFNGAPHSSQNPHMQPGQAANPNQPPQQHHPQQQQPQQMMYNPQQYPMGPAQGPPFPGAPNMMPGVGPAAGMMQNTGMPHMANGQMSNYPTPYSNSPYGAGIPTSVAPQMNAPPNYAMGAGMPMPGFPMHPSQMNPQQQQQMMQRMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQHHQQQQQQQQQQQQQQQQQQQQQHHQQQQHQQQQHQQQPQQQQPQTQPSASGMPNTTPQRPYPGQNQGHSQGPGLQGTPTPSNGMSAQQPQFAPPSNHQGTPQSQTPSNPQHQQPQQPPSATIQTPQTPTFPSNVHAPATNGTASTPLSPGADSRDKERVSVILEINNELLVEAMQLQHTQSLLKKEHTSPMDGNLSDVDKKNKEDEELLAQDYLQCMRRLQTNLSYLASLADKKGALQAPPCPMYLKPPPLHTKVKLRPMQSPDGGEAKPEASDREETAKYMTDLYTKLQGLYPDIDPNKEPTYQVPANRTNNVKPGAQTPSQASPVPGNKKTPTMAAAPAPPQMQMHMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8T9</accession>
    <name>A0ABR1W8T9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667366.1">
        <property type="nucleotide sequence ID" value="XM_066812024.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045084"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="77" mass="7893" checksum="157840E2118F0536" modified="2025-10-08" version="1">MSFSGSSAEFILATSTVCGGPPCHRATPHTTPHKAVDVGLALCPSPLSMDVHAVDVSGGHAGRDQPINASRCESRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W905</accession>
    <name>A0ABR1W905_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_007779</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667436.1">
        <property type="nucleotide sequence ID" value="XM_066812094.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045154"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF32">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046576617" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="13">
        <location>
            <begin position="22"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="14">
        <location>
            <begin position="22"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="339"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="413"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8079961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="434" mass="45502" checksum="FDD2D8D9A4A15084" modified="2025-10-08" version="1">MRFSPSLLFGFLGTLAATAHGHTIFTTLYVDGQSQGDGTCVRMSMNGAHSTDPIAGLGNDNMACGVDGGKAVAYTCPAGAGSTLTFEWREFANLEQPGSIDISHKGPCAVYIKQVGDMATSTAAGSGWVKIWDEGFDSATGKWCTEKLIDNDGLLSVQIPTNVPTGDYLVRPELLALHEADKGDPQFYVGCAQVAIKGSSSGKLNVPADYSVSIPGHVEAGESSVSFNIYQPKFPYPVPGPKVWNTQSADAPVVRVPSDDHSWITGAQTVPATCLLKSANWCGVEVPDYKTEDGCWKASEACYKQADTCYKTAPPSGSRNCKVWETKCQGIEEACSSGNFQGPPNKGKKLESAEPEPKTKIPTAGNVSSGASSAQKKAVVAGAGAGDAISTKTSSAGAASAESAIDVPVQGKRGCKSQKVRRAHADLHARRWNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9J8</accession>
    <name>A0ABR1W9J8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Protein transport protein BOS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_007915</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">SNARE required for protein transport between the ER and the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 12">Belongs to the BOS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667572.1">
        <property type="nucleotide sequence ID" value="XM_066812230.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045290"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15863">
        <property type="entry name" value="SNARE_GS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027027">
        <property type="entry name" value="GOSR2/Membrin/Bos1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF1">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028865">
        <property type="entry name" value="Membrin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="88"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00040957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR028865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8080097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="243" mass="27097" checksum="5FC8FBF3EA1BCB7C" modified="2025-10-08" version="1">MHFPLIALKQSTAVRRDLTSLSSGGAPTPAALGSLSASLTSFGRTLDEYGDLAKHELVVAKQEKAFERLKNFRAELADYRQQFNALKEQRDEAQHTQSRTELLGRRPFATSTPENPYANASPGEVPTNRYGSGGAYGGGQMSMGTGDYTRETHALREQNFFDNTNSALDEYIARGQAVLGDLGAQREMLKNTQKRLYSVANTLGISGDTIRMIERRAMQDKWIFWAGAIIFFAFCWLCLHFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9Q1</accession>
    <name>A0ABR1W9Q1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667693.1">
        <property type="nucleotide sequence ID" value="XM_066812351.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045411"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF10">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="41"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="311" mass="35142" checksum="ECC879CD6838E818" modified="2025-10-08" version="1">MIPTYIPVQKIEAKNCITYAYRRLGPAEGIPLVMHMHVRASMGYWDPVFVRPLALKRPVIMFDPPAVGQSSGTTERIPSDIKDMGDDLNEFLDALSLDFIDLLGFSMGSMASQMAILAKPERVRRLVLIGADPSGPTPGDHFWPRTDPDLNRFLMLQKSASEADWQRAYTLVFFRNEPQGVAAADAYFGRLRESEYNENAGEGRLPAFQDVEGFMIQLGAIKDWCKPKDKALHSFYRMHELTMPTLVMTGDDDYVVPTPRSYELLHALPNCQLVIWPRAGHASIWQYAESNAARVNEFLDSDPENYAEPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAL0</accession>
    <name>A0ABR1WAL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA damage-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008339</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DDB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667996.1">
        <property type="nucleotide sequence ID" value="XM_066812654.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045714"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="6">
        <location>
            <begin position="12"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="7">
        <location>
            <begin position="416"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="5">
        <location>
            <begin position="773"/>
            <end position="1101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1132" mass="126813" checksum="6F6C6ABC22AA3B6D" modified="2025-10-08" version="1">MEADLGVFLQTSKANRLEFWKVDRETGLLVEVDSKVVNGTITMLQRLRPRDADIDQLFIGTDRFQYFTLGWDDATEGLNLYSKTYDKNERHMRDSQSQDQCIVDPSGRFMIMLIWEGVMNVARMHPMKTRRFELDFQDQIRIRELFIRSATFLHSETAQPKVAFLYQTRTDNPDAQLVTYRLYSDDRNNTVSNFETKDQIDRFEIQDPGAAMLIPVGRGEEDHKRYIVRNAQQARAQLGGFIVVGETRLLYYDDAARKTVETALVESSIFVAWAEYNVSHYFIGDDYGTMWLLEIQLENGAVVTGLEMKKIGTTSRANRLVYLGDNMLFVASHYGNSQLFRVDPENHTLELVQELTNISPILDFTIMDMGNREGEEQTVNEYSSGQARIVAGSGVHKDGSLRSVRSGVGLEDVGILAEMDNIRSLFPIRTGASSKYDTLLVSFLTETRAFAFSASGDIEEVEQFRGTSLNEQTLVAQNLSDGRLIQVTPSRVRLIDVEGGVAISSWSGAAGQTITNASANNDWVLLSVNGNILVLLKIEHDLIRQQENDLGEKEQVACIHLPPQYPSIGVVGFWKSGTISIMDLKTLQPLHSESLRKQDDLTSIPRDIVLAQILPPESSGPSLFVAMEDGFVFTFNVSKSDFALSGRKSIVLGTRHARLQLLPRPNGVYNVFSTSEHSSLIYASHGRIIYSAVTAQDATCVCPFDTEAFPDCMALATENTLKLALIDDERRTYVQTLPMGQTVRRIAYSRNERAFGLGCVKREVVNNEEIITSFFRLVDEVVFDKIGEDLVLEGSSGPEMVEAVFRAELTDSYGDKVERFLVGTSYLSDVQPNPSSQDDFRGRILVVGIDSDRNPYVVTQRGVKGACRCFSVVGDYIVAALAKTVVVYRYEEVSTTSAKMDRVASYRPSTYPVDLAVEGDTIAVADLMKSMSLVKFTPPTDDGPAKLEELGRHYQASWATSICHIEGESWLESDAHGNLMVLRRNLSGVTEDDKKSMAITSEFNLGDMVNRIRKVTVDASENAIVVPRAFLGTVEGGIYLFGTMSDSTLDLLHRLQEVLVGAIETVGELQFKGFRSFRNEQREEAEPYRYIDGELIERFLDADEETQEHMVKGLGPDVESIRNLVEELKRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAQ2</accession>
    <name>A0ABR1WAQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Echinocandin B biosynthetic cluster transcription factor ecdB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007940</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667597.1">
        <property type="nucleotide sequence ID" value="XM_066812255.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045315"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF2">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="136"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="707" mass="77847" checksum="53C6734E1A34BCFF" modified="2025-10-08" version="1">MATAALQPPKLSPSSAGDSPHSIGGASSTSRPYPLPTRDSFSIEAPSPQLNPVNGSALKSPTAAKVQKTSGFSREGILGSAQKARNLSQSSEVRPEPYTTVNGMSKGSSDEGTINPLKRRNTDATVDYPRRRATIACEVCRSRKSRCDGTKPKCKLCTELGAECIYREPGIKLDAGDKLILERLTRIESLLQMNLVGGGNPMQISGESPPISNGTVALTGDNLLAHDANRFVSIIPSGGLGTWTSGTNISTMPKVHTNAALHLLQWPLIRDLVSRPYDPQILLQLEMAREPLPSLAKTPCVDLSNTNAYIEAYFDRVNIWYSCVNPYTWRSHYRSALSNGFREGPESCIVLLVLALGQASLRGSISRIVPHEDPPGLQYFTAAWSLLPGMMTTNSVLAAQCHLLAAAYLFYLVRPLEAWNLLCTTSNKLQLLLMSPNRVPEDQRELLERIYWNALLFESDLLAELDLPHSGVVQLEEHVGLPGGFQGEESEAVGRDDLWYFLAEIALRRLLNRVSQLIYSKDSMASTTSLEPVVAELDFQLTQWYESLPVALQFPFTRAALPDPVQTVLRLRFFACRTIIYRPYILAVLDNEQAIMDPAVRESCHKCLEASIRQLEHIGAHHAGHMPYLWQGALSIVSQTLLVMGATMSPSLSSIILTLLPHREAMDQIINDVIMDIERMAVLAPSLSLAAEIIKEAEVRRRSFLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAS7</accession>
    <name>A0ABR1WAS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THO complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008409</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668066.1">
        <property type="nucleotide sequence ID" value="XM_066812724.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045784"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021418">
        <property type="entry name" value="THO_THOC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021726">
        <property type="entry name" value="THO_THOC2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11262">
        <property type="entry name" value="Tho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11732">
        <property type="entry name" value="Thoc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="8">
        <location>
            <begin position="125"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 N-terminal" evidence="7">
        <location>
            <begin position="834"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 C-terminal" evidence="6">
        <location>
            <begin position="1196"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="517"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1108"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1529"/>
            <end position="2384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="527"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="567"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1617"/>
            <end position="1629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1644"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1676"/>
            <end position="1709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1716"/>
            <end position="1770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1771"/>
            <end position="1782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1836"/>
            <end position="1875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1882"/>
            <end position="1897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2001"/>
            <end position="2010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2035"/>
            <end position="2045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2064"/>
            <end position="2077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2091"/>
            <end position="2101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2116"/>
            <end position="2127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2184"/>
            <end position="2196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2207"/>
            <end position="2254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2265"/>
            <end position="2276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2301"/>
            <end position="2322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="2323"/>
            <end position="2341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2342"/>
            <end position="2358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2384" mass="263014" checksum="4B6530D64A1E0C98" modified="2025-10-08" version="1">MPPKRKRNEPASDTPRPSPHRPLDTSLAQHDRDGYEGGNRRRSGNAGGGRNTRSRNAERRDSNASTNQTMNNRGPITSPVARPSSSASQKAPQSVNIPPPATPTASMAPPPSPAISSNYTYAVLTSPRLSAWKQSGRQEIIEHGIASRNDEDVEEIATISQEFTRAVMENRLDPTEAGSCIKEILGPQPETDDSQGLDFSFNAHDLFVDTISMFFDSEDEASKPRFRDFIVASEVSPELLRQALDVSVLDKLGLVRNTFARMGIRYATNMLYRQNNYNLLREESEGFAKLITELYWTPHSLNQEQLTRAGVEAGFERIKGLIGTFDMDVGRVLDIVIDVFASTMMRTFRYFTMFLRVSSWWPSSQIENYDPVITGGLPRWALPGASFQLTPDEQADMDSRRVQRDTAFWDRAREAHLDAFFELGGRRATDADIESFLNTAPSSRAKTEFELEWIKATKTLPPSGNQTAAQLFGFKLRFYTSQARDKDEIIPANLFYLAAYLIKVGFFSLPRLVSPPLARGRQNGCSQERRTQELEEKEKKDRQGAEPNALLRAGALPDDTLPTLPTRTRDTQATKPEADSKDASAKAPLEENLPEPKEVLKVDLVQHLLLIGAIPEALFLLGRFPWLTEAYPDEIISPINRILLFSIEKVFQDTRPKETTPFAAGTPKPLKWPHANGFNRGLPYEYYLKEWSDNVPVCHTVDDVFTLCSTLLNVSGVNIGRSPALLKKLTAIGARSLHQDISQSNIDRWQDLLKRLIVPALNLATSNVDVVDAVWNLLKHYPSQVRYNIYAECYEGQISRVPAMTKAFKYARLDTLSILKRLSLQNISSSAKHLAKVALFSPGIVCKVALDQIEAYSNLIEAFVECAKYFTDLGHDVLVWSLMSSLGGKQRSRTQEGSVLLTSKWLQALSKFSGKVFRRYGNMNPTPLIQYVNDQLSRGNSTDLVILRELVTSMGGIVSDIDFTDAQLAALSGGEELRRQTFINLGDKRFESTKSGSRFMKALVQTELAPRLLTNMAQYRQSAIYHLSESDTHIKYIATLIDDSQQALVQYVELLRSNLQPEEFDNLVPSISELMTEYGLDADLAFLIGRVSLAHYLTGPGAVGFKGRRLSSSTPVESAADVEGDIPMENKDDGNNGLVAPPSSEDMMAIDGQDNKVPSVEGPPTPSATSQKPDHFLEVLHPIIQAVQAQLPPDLWSSISPEFYVLFWALQTNDLSIPASSYNAETVRISRELDFLKKDRSDMTKTGQDKNRRRRDELTQIASKLTTEVNHVKERVGKTKVMLLKSAPAWISGGKDRSNMIADVLIEECIVPRMMLSPGDADFCHKMIRFLHDNQVANFKITALYERFFSVNRLRSMLFGCSIREAEFLGRFIKLALGDLAKWHKSKDAYEKEATRNGKHAGFAITVDEEGKPSSMMEHDHFRDQLWTWHRNLCAALKSCLQGTEWMHIRNAITILKAVLDYFPAVDFMGRQFMQLLQKIAEREAATKNDEDGQGHRVDLSVTANTAASALKKHDSRWVMVQAFRSNVTGDTSEEKRAADSSKPPSLRPNAPEFKPTSLAGRPKPTADDEDGEVKDHRPGSAASADTQRKDNEALPPSHKPSTLPQKTELARPGRPSTPTARPSTQSPAPNARREPLKSSTLPSLPPGLPSRPDVPLPGHFRQDEYAQVRAVAEGGHTREHRDVRERRDVRDTRDGREPREPRESRASEGTRTTRPPRDSFSNDRRPADSLPREASRSDRDRTTPRTEGPPRWEPPATHDRETRSSRDRAASATAGRTTDSSRGARDAQPDTKSMPPPAQTEIPGPTVNPERARLIGQQAVHQERKVGIVAAVTIHPRERPSVPKRDPGEQNRDDRSSRPYRGDHSTPARDERNEAIPPSGHRVDREGDRTTEKARDVGSVFQSTPSGARGEAERLRASQQDPNYGRLNAIPSVTDMPTNTPEGPRGRGRNMTRPPPPQNQQQPVRGDGRYPNMDVPQRGASPERHLPPTGPASSRPRRGPPAAGSGNAPANPPPAPNSSGPGIHPDRLRQLGVAPAQPSSPQSAFPGSGVNSVAVHPDRMNQIGANQPPSGPSQHGRSLPPLQTPDRPSMPSNHGSSRQPSGAMPITPGPERNNSPSVPTGPSGSTDRAKGGSRRQLAGINNLLSGADPAGRGGSLRGRSSRSNLAGSDAQVLTGASPVSTPIHERPEPFADRVDQPNSSRGGANGDDRSGRGDRERSRRHHDGSERVTRSRDQSPTRDSRSKDHRDYHEREVAAGVPGSGARDGGREFSRRSGRESSNNARDSQFGGRAEVVGNGRGDGGGRESRHRGDGGSGRHEEHSRSGGGGRGGGGHGGGIGGTPRGEDHRSREPRGEDGGRGSRKRRSEEGGYSAPTPDSHKRQRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB25</accession>
    <name>A0ABR1WB25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008513</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668170.1">
        <property type="nucleotide sequence ID" value="XM_066812828.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045888"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057941">
        <property type="entry name" value="TPR_TNPO3_IPO13_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057942">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058537">
        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF53">
        <property type="entry name" value="MRNA TRANSPORT REGULATOR MTR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24138">
        <property type="entry name" value="TPR_TNPO3_IPO13_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24140">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24139">
        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="3">
        <location>
            <begin position="35"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="962" mass="108675" checksum="637A16B31B492A55" modified="2025-10-08" version="1">MAANGVGDQAAFAPAAVLDAVLTMRSNDADRKKKAATYLENFQKSPSAWTTTITILKSDAEPEAKVFAATTLKGKITYDLSTQVPAEEHPAVRAQLLELLQVYASGPRPIRVQLCVCLAILAIQMTQWKDVLPLVVSSLGNQPESHTCILDFLRVLPEEVTEGRKISLSEEELALRTTELLSDNAPQVVQLLINYAHSSPEAATNPQLLECITSWLREVPVNDFVNSPLLGVVFNALESDRSFQEAAECLSSIVRETREVDDNVASINIMLPRVIGLRPKIQKFVEEEDTEAYKSLTRVFSDAGIAWVVAIARETAHFRPLIDAILECVERDEERDVIEYTFDFWYELKQYLVLERYIQARMELVDVYSKLVDSLLKHLQYPDSEDGRDANARELFSNDLVAEEKFREFRHHMGDTLKDACEVMGVTDCLTKVLDAIRIWTQKYGGMATATSVPHWQELEAPLFSMRAMGRMVEKDESIVLPQLMPLLIQIPAHEKLRFATIMVLGRYTEWTAAHPELFEGQFNYIVSSFQTDSKEVVRAAAMAIKYFCQDCKHLLGVQVDQLQQFYDQVLDTLQDASQEEITEGVATVVAMQPKTDIYRLLKLYCDPLVQRLMTKANNATDEPGKLAVADHLQLITMFVQIVVTVPPVARGEEDPAVKYWVEVFPILAKVLESFVDFSPICERICRCWRFIVISHRGAMTPLLPEMANKLAQGFQSSRQGCFLWVTSAILREFSDDREHVDQSITDSIYTFFEAQATNVLRFISELSPQELPDVTEDFFRLMIDALLYYPHKLIPSQLFTPIFEAAISVLGLEQRPPLSATLHYHVSPGVDVQLQNMVKQLIISQGDALVKRLLAGMMISFPRDCFADASGALLSLFEIMPTETAAWVERTLTMLPQGTVTPAEVERLMVKIRERLGANDTGEVRQIRSILQDFTNTYRRRYVAPRDGLGDLEASRFRFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBA0</accession>
    <name>A0ABR1WBA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668250.1">
        <property type="nucleotide sequence ID" value="XM_066812908.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045968"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="188"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="686" mass="76694" checksum="A6F842AD997C4E06" modified="2025-10-08" version="1">MICPSCKKSIFESTRSWGYHQLPSAPQASLPLEANDCILCGWLEGEAKSWLGSDFQPASKNGFYRWTIHRSPRFRESEVSCSLHFRPDVSQFPQLRNAPTKVFHLIGAESVRVNLALGEGLNADAVGSQLEAWLENCRATHRGRCAVPDNPSWVPKRLVDLATLAEGRVVVRETKSLSSPSPSHKPRFVTLSHCWGGPTGPRMIQLVPETLDIFTDPERGIKIEELPRNFRDAVVIARRLKTQYIWIDSLCILQDGEEFKTEGQLMHLVYRNSYCNLAAAASSDCQGGLFRDRRKVDSFGGGIIETSEASLFGKGTWRVFPSECWSDQLLMQPLYRRGWVFQERMLSPRILHFAAGQVFWDCASTTACEVLPEGLPWQLDAASSTEKYWRERLQLIQGTDSSAPKKFVGSADVSFESFWREAVLNYTSCNLTQNRDRLLAIWGVAKLVRDQFRLDNWEEDYGVGLWSSQLAEQLAWRVQDPGPARRSPELAGLWPSWSWASVVGAIETQLRSSEPGQFYAATGHDGAVRSVFLKVVVEGQMAATHEDATKGELSQDNAQAYRLRLGDQTVDAGGQCTGLFKVSPDATSEFSQNSGGDCYLTILTASRDQEQVLQHSGWSSDEDEEPSKPSWIHGTGLVVVRAALSEGEDNAKDDQYRRIGVCNFEGLSSDDFTRLEQTCVSDIWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBD2</accession>
    <name>A0ABR1WBD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668202.1">
        <property type="nucleotide sequence ID" value="XM_066812860.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045920"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024624">
        <property type="entry name" value="Pyridox_Oxase_Alr4036_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243">
        <property type="entry name" value="AGL049CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243:SF1">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE ALR4036 FAMILY FMN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12766">
        <property type="entry name" value="Pyridox_oxase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding" evidence="1">
        <location>
            <begin position="8"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="32036" checksum="26799643E114D40D" modified="2025-10-08" version="1">MATSREPAPWRDLFVEHVENMRPPEFVLSTIRRIPAASAGFGINDGNGFCLTPRARTCVYRGMWASIPVNPKNDAELNPDVYEADMLTFTTDVRMDKMPELWEDGAVAAGAESKEGNGAWTGSGGGGPVEAVFWAKEPMVQWRIRGKAIVVGPDIEESDAGRAAQKALMCRMRKREGASDDHWSFAKEVTAHFGNLSPGMRGTFRNPPPGTPVDSPVDDGLGLGQKVTDLQDNIARKNFRVVVIVPYEVDRTDLSNPERGRRWIYRRTVDQKPKPEGAEGGWEKVELWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC09</accession>
    <name>A0ABR1WC09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667174.1">
        <property type="nucleotide sequence ID" value="XM_066811832.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044892"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="163" mass="18938" checksum="4309E329FC8B6815" modified="2025-10-08" version="1">MVRQSRTRVITRIQNASVLLDLAYPPMLLLRLRYIQGKHSIFPRQVKIARSHIAESMCQGSLKFVRHDPVFDFDVYTEHPDFINPLDLSNLLLFLYGKARFMFALRRNVYIIYIKPSEVSLGQSAPNPSQPQPEHVLTNTFADRRHPTTNRYEHVKYGKIAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE54</accession>
    <name>A0ABR1WE54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667863.1">
        <property type="nucleotide sequence ID" value="XM_066812521.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045581"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="82"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="295" mass="32225" checksum="AD75013FE3A3E35C" modified="2025-10-08" version="1">MSSSNGAQNNFTSVNNSSQQQYAAQSQAPHQAQGQQQQHAQDRPNPSRRKLPTLGHGLLPLDDGLSVQEYERRRIHNNTQAEENKRLKRQRNNDAARRSRLRRLNLIDTLTEENQRLKEENGALVRERDYWKGIVDRMQGLTVGGGHAQQTQQVDRPVPQQHSTPSQGLAYPAALTPQTAMASAALLQLSATPAPRQQAHTSRVPAAQSQMMSQFPAQARGPAPARAGTTTRTSAASGRAGSGFAGPSRQTAASSAGTTTASDIDELFLQIAEYDEHVRNEQSDDPLANFDFSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEV4</accession>
    <name>A0ABR1WEV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008431</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668088.1">
        <property type="nucleotide sequence ID" value="XM_066812746.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045806"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="321" mass="34363" checksum="1D9A3F583CB888B3" modified="2025-10-08" version="1">MASQALYKLPEDAVWFVTGSSSGIGLALAKLIASHPTHRLVATARDSSKLATEIAATTPERVHTVDLDVTSDKSIAAALDSAVSKFGRVDVLVNNAGYGLMGDAESALQPEDHAKARQVVETDFWGTATLSLHAVRVFRDENPKTGGPVGGVVLNVTSLGGFAGFPGSAFYHAAKFAVEGFTESVSKEVRPEWNVHFCLVEPGGTRTNFAGAGTMQWLSPHPAYAAADTPTRLLEGYVKNPDMQKTWTPAERVAMAMYQVVARAKEKALPSRLPLTAGAWQVIKADIAAVDKELEEVKELSFSVEVDNTNEAGTFLEKTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFB8</accession>
    <name>A0ABR1WFB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CorA-like transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668268.1">
        <property type="nucleotide sequence ID" value="XM_066812926.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045986"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058257">
        <property type="entry name" value="CorA-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26616">
        <property type="entry name" value="CorA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="461"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="CorA-like transporter" evidence="3">
        <location>
            <begin position="16"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="550" mass="62969" checksum="1FEDB9F9C922B1C7" modified="2025-10-08" version="1">MRYGSMDHTQEFLEKYQRHDEFPRTLVHDKYGHRSDYYKQQLDKHEEKIFCTANDDDGRSNKDVFVKIRDYETTDKLRVRNEHACRNEQELMEALGEDGTEQDWLSADAACRVILLETVKAQSRRLNLTKSMFTRIMTYHQVSSCFLNFVTFSGSMTGKSDLGLGGFRSESCIRKPKFISRKLDRSGRHIHVSYILKTIERNLLRGQVQAGDPDNEIEWIRPHTAVHHQFDLETGKSLWILTSPLIPVPQSGGEKPKGQNTIWRSHLNKPLNEFRKQKDQPFDISADRQVYTRQASPVDDEDLQKLYKFMDDADTCILRLEDNLQVISSLGAFYNKELKTEAAKEPRMTEWRDEREDIIDNFLAELDERQLELESVAQRARNLVGTAKSRESVISKVLQNQTNNVMLDLTKQGHEEAVVMGLFQAIAIFYLPMTVVSAVFSTDIVKFQDLEPGETQKWSRLALGTWFATSIGLTIVTLIISEVWKRWKREQNRVRLEGREQRPGAVMAAAAAAAAKSQTSTPSTASINGLSPPGSARTRRANGRIPLLPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMD7</accession>
    <name>A0ABR1WMD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669168.1">
        <property type="nucleotide sequence ID" value="XM_066810245.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043305"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="230" mass="25085" checksum="9F87CC53441768CB" modified="2025-10-08" version="1">MTKDWENYKGTILALYEHQTLSQVMEIMERDYNFSASTRAYRQKLDKWGKRKYKKRKGKSDNGSEVSDADSAEEAAGSSISASPEVSRRRGDAHAYQRQQQQSASTGSYGTDAATYQAGDGSYALHHSGTDASSNNYNPAQYQSANAYGAADNNTYWANYSATATQSYSQAPPDPNAAAYGYGGVSYPTDNTAAAPFQYMDASGASYSMDNQMDYNATYPGGSWDQTQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN04</accession>
    <name>A0ABR1WN04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006186</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669424.1">
        <property type="nucleotide sequence ID" value="XM_066810501.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043561"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF18">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G12480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="292" mass="30455" checksum="7F29398F3CBCC80A" modified="2025-10-08" version="1">MSSSQATASPSVAAGDIFNVNGMVAVVTGGGTGIGLMMSRALAENGAAKVYILGRRADVLQEAAKTVGQPSVVVPLACDVTSKDSLKAAVDQVKRESGFVNLLVCNSGVSGPSTKRASPDMSVAEFAEENFNVPIEDFTQTFAVNTSAVWYTTMAFLPLLDAGNKKGNVWQKSQVIATSSIAGFNKVNTGGFAYGQSKAACTHLMKQLSVSLPTFDIRANVICPGLYPSEMSAPIIERQGGFGKDAIPLERAGDEQDLAGTILYLASRAGAYCNGTIIVSDGGRLTTFPSTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP79</accession>
    <name>A0ABR1WP79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668799.1">
        <property type="nucleotide sequence ID" value="XM_066809876.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042936"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="entry name" value="Serralysin-like metalloprotease, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="Adhesin YadA, collagen-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="278" mass="27385" checksum="D80B47877003A5B2" modified="2025-10-08" version="1">MTVTVPAPVANTAATLASETCTEEEQQQTSTTVTPVANTAATLSSDTCTEEQQTSTTVPPVVNTATLTETCSEEHTSTVPRVVSTATMTSSFTHFPAQNETASAGPTATTCTEGEGLSSGIPVGSSSTASSPASISMGVPASSSSPASISMGVPASSSSPASISMGVPASSSSPDSISMGVPATTSATSAVNGQETTSSSVDSISMGVPADSTTAPVPATTSESSPEDSSSPSTAYPTSSTTPLPVTAGSSALEAWSWYKRMPGTMGIAGLMFVAGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPT2</accession>
    <name>A0ABR1WPT2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfite oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005727</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668965.1">
        <property type="nucleotide sequence ID" value="XM_066810042.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043102"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02110">
        <property type="entry name" value="SO_family_Moco_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF6">
        <property type="entry name" value="SULFITE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase molybdopterin-binding" evidence="5">
        <location>
            <begin position="130"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Moybdenum cofactor oxidoreductase dimerisation" evidence="6">
        <location>
            <begin position="337"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="58643" checksum="F7182D3D74D17781" modified="2025-10-08" version="1">MAPAEPNALAFRPKGEPPVFEEERKGWKGYIEWEKYPEKKKQAAEILKKYDFPVPPEFQLQPLPKTNPILTGERWKQYHYAMGPNLEKLPDKSWEYVKRRNEEVLLNSRNQKRLVESEITPNKDHFVRNHGGIPEIDPEEYTLDISGLVKNPKRLTLADLQNEDLFPRQTNTVTLQCSGTRRMEQIAVYPGDGDELINAPWAEGAIGNARWTGVSLKKVIKHCGGLIDGADNLEFYGADTYFKKGQVYNYVVSVPWRKVKANEVLLAWEMNGEPLPKIHGFPLRTVVFGYIGARSCKWLYEIKGIKGPSQAPVQKKEYLYYTPQVGKQNAMYSNGFSIQDMPVSSAIMSPTDMDQIVHDGSVRLKGWAYSGGGRWPVRVEVSGDGGSVWYEVPPENMSTKYFHGWRLWEIEMPVDAEGWLEFCVRCWDNALNTQPTFVRSAWNWDLHVTSSCHRVKIYSMNRSRPQTAARLKLLEEKGMSILPITQPLEIDLETDEHYDEAMEAIGGRDPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ58</accession>
    <name>A0ABR1WQ58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670183.1">
        <property type="nucleotide sequence ID" value="XM_066811260.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044320"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="96" mass="11113" checksum="72708CABD1979053" modified="2025-10-08" version="1">MFGTALETVMWWCSAMGIMKGYPLFCILAFSLGKLMKVRKRDDYLDTAVLVFCMWCMLLVYVAASVYVVAETCISLYAVPARVYWIPHWVKMLPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQR2</accession>
    <name>A0ABR1WQR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA stability protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006086</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the endosulfine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669324.1">
        <property type="nucleotide sequence ID" value="XM_066810401.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043461"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006760">
        <property type="entry name" value="Endosulphine"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10358">
        <property type="entry name" value="ENDOSULFINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10358:SF6">
        <property type="entry name" value="ENDOSULFINE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04667">
        <property type="entry name" value="Endosulfine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="49"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="162" mass="16994" checksum="BDA2062393DAD2CC" modified="2025-10-08" version="1">MNPHQKNKIDIKSLSPDEQRLFRLYGKLPSKSDHFAKHLKDRKYFDSGDYAMSKAGKGDSVDTGSVGTQHPTPENVPHLSSPNGTNPGHAQHHGSISGTSPGGMGGAGGITGHPGNSSSPIKESSFLNRETSADDAEEKENAAAAAPATEDGAEPQGIPIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWT1</accession>
    <name>A0ABR1WWT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670468.1">
        <property type="nucleotide sequence ID" value="XM_066806850.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039910"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF26">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="10"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="335" mass="36658" checksum="6197822C1069F148" modified="2025-10-08" version="1">MSKLRQSLCGGSVANRFLAIPGWRVRGLTRNPNSAKAKAWTDKGVDIVKGDHDDIYSLKAAFQGAHAIFAVTDWAANYARVSEDKSLQDQARAAGRSLEEYAGDLETSQGINLAQAASDPSVLATLERFVFSTLAAVREISGGRYTRAYEFDSKAAAEKSMREELPELGARLNTVTMGIFQETWRDISAFRPHKLADGTFEYLRLAVSGPYQANPEVVATRDTGAFVEALVLDYPAGTDVLGASEIVTKSEYAALWGRTQGVKATVRDVSEEEYIKYLPEGFEATIVDDLRFFAEFGYAGGNPRVKTPAELGIKTSSLEEFVRGEDWSAVLRGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXI8</accession>
    <name>A0ABR1WXI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SMODS and SLOG-associating 2TM effector domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670706.1">
        <property type="nucleotide sequence ID" value="XM_066807088.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040148"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041622">
        <property type="entry name" value="SLATT_fungi"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033635">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793">
        <property type="entry name" value="SLATT_FUNGAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793:SF3">
        <property type="entry name" value="SMODS AND SLOG-ASSOCIATING 2TM EFFECTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18142">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMODS and SLOG-associating 2TM effector" evidence="2">
        <location>
            <begin position="136"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="365" mass="40046" checksum="0A9F57417EC3F8AD" modified="2025-10-08" version="1">MASFIEATLRLIFKRKPRQGTLKSDVESAATVPAPSAFTASAAAPRTSATLSPTVAAPSSAQHLHTWNFGGGSNHHQGVVIPSDDPLTMFRLVLGITDAPRLGFAEQNLVGTRPASNIGIYARVVHSEQKSKDSFKIIVAAALTAMGAAGTSSQAITAFGAINTIIAGFLTFLKGSGLPGRLKYYGNEWKKIREYIEQRERDFSREGCTLDVHEVVNTVEKMYTHVKEDIEVNTPDGYTSVTNSRRMEQANVGKVGGFDMSKLEGIANKLTGLDGTIESLKERVEMMLQARAQGVSENIHKHEKQIGDEIRGFEKAFVKEVEDHKDRVEREARERQTHVVQVLDEGLRTLAPHEHRRKEDGDAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXS7</accession>
    <name>A0ABR1WXS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP synthase subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002929</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the eukaryotic ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670862.1">
        <property type="nucleotide sequence ID" value="XM_066807244.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040304"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008688">
        <property type="entry name" value="ATP_synth_Bsub_B/MI25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013837">
        <property type="entry name" value="ATP_synth_F0_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733:SF3">
        <property type="entry name" value="ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE B CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05405">
        <property type="entry name" value="Mt_ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161060">
        <property type="entry name" value="ATP synthase B chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0138">CF(0)</keyword>
    <keyword evidence="3 8" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8087968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="247" mass="26797" checksum="150DBB13A67B7E3B" modified="2025-10-08" version="1">MASRLAKTAFGAARLRPVVSSRALPALASSVSANRYASNVPSTNTPDPKTKAQSILDSLPGNSLMSKSAILSSAAGLSIYAISSEYYVVNEESVVAFCLLSVWGALIKYGGPMYKEWAEAQNAKIKGILNAARADHTQAVQDRIDNVQQMGGVIDTTKALFEVSKETAQLEAKAYELEQTTALAAEAKTVLDSWVRYEGQVKQRQQRELAENVIAKVKKELENPKVLQQILQQSIADVERIVSAKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY13</accession>
    <name>A0ABR1WY13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670940.1">
        <property type="nucleotide sequence ID" value="XM_066807322.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040382"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="94" mass="9543" checksum="1876FDA5B65E2D18" modified="2025-10-08" version="1">MSSSDNNNTQPGLVAGHAEYVKGAAEQSTIGSATGSTAWQSSGEQAKAHAVGVMKQASEGRDPTQGYGKLEETAGKVTGCEGMQEEGAASKKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYK7</accession>
    <name>A0ABR1WYK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003148</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671081.1">
        <property type="nucleotide sequence ID" value="XM_066807463.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040523"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="175" mass="19674" checksum="B0EF3A731F00199B" modified="2025-10-08" version="1">MAAGIAKKYSFDVVYLVSLWPQEPKDPLYSTVQGSIAKHQAQVCSTGTKQHEAPSNGRFLAAFGLSDLEEPFKIYTKVHLKILQFTEWLEYEKSEAASETLDRGWMHSFLCQRAPAKHETAECPMNSGLVFAAYRKQKNPLSVPAKGTWERKQFLEDLHADANILVDTLSERALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYM6</accession>
    <name>A0ABR1WYM6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carbohydrate esterase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003234</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671167.1">
        <property type="nucleotide sequence ID" value="XM_066807549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040609"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10917">
        <property type="entry name" value="CE4_NodB_like_6s_7s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF6">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="525"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="686" mass="74174" checksum="50D614330B6B960D" modified="2025-10-08" version="1">MTSISVIDGSLTFTPKANSYFYETFPCTQAKNDGYNAVSFSVIGPAGGAASLEIQTKSSCSASAYSSSYFTVSGLTGSKQTVTVPLSSFSGAKINAITGLVWSSFSKTGVKWVLNDVQFVCRGTNPAPSTPGSCSNLLIDDWESQSRLTFLYYNAMIKPSSDDATMNSVVVSNDNHVTFTPKNTDSYFYSQVGCVNTHNVYGGISLPIKAPRGAKITVQLSSPAQCGDDVDKVNSAQTSTELGWTFDGTEKLYSIPFSKFSKLDLTKIRTVFFTGFTGPVTFGPMAFYCGSTPSQYQVSSTTAPAGPTSTVPAPSSTASALVIDDFASNGANALGFWHGGDEEISLTWGNKQLTIKSSDSDYAFYTQLSGSCRNLHSFDGSYLHIAYSGSNKFSIALQQHNSQCNENIAPFPETWDSLEAARYASASDIYIPISHFNIDRSRVIGLAFKGFYTTESVVLKKVEIVPSIPATFQIPSKLPSGNFVFACKRPNSFAFAIDDGDPALAQQVMRIVREEDIKVTFFTSQGHQIALHSFTHPKMEGLPDYAAIDWEYNNDIATVKKTFDGLVTPYFRAPFGNEGARMRQRLAVALGTEAPYIVQWSVDVEDWLYATGPTPEKQLDAFKRDLAKGPYSHDLVPVALYPAAVARDSNLLGNHRRPGHGSLLAGAYAKDGIASSCPGLRNEAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZD9</accession>
    <name>A0ABR1WZD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003498</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671431.1">
        <property type="nucleotide sequence ID" value="XM_066807813.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040873"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="453" mass="50916" checksum="0AE5A15146D9C31F" modified="2025-10-08" version="1">MEVTFEYLSWACLSILVASLVTLVRFSLKSLRPRNYPPGPPALPFIGNVHHFATPKPFLKFAEWRAKYGDIIGLKTGPGNLVVLNSARLVRDLLDKRGSIYSGRPNDYIGYLKQWRTAVVRHLLGPTGVEQVLPVLEAMAAHLAYRLAADPGRFADHFRNWALATPLLAICGHRGEQKEAALVDLFYGNQDNWLTLLTPGVAPPVEMFPVLKWVPAFLAKWKRTARDLRRNQQGFYGMMLESAKEERRQRKAASLSSKEAPLRYESLMARILRAQEESGKAEFDDCQLAYLGGGLLDAAVDTTYSTALTFVKILAARPEIMKKAQAEIESVCGADNGPPQPKDINKLPYLRAYSSLEIARPQQPPARPRRRRHRWRVPSAQRTVVLHNTWAIERDPELYHDPDTFDPERYLSNIYGVKPSAEARCRAEGRKPNYAFGSGRRQCPGICSPLAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZX8</accession>
    <name>A0ABR1WZX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003615</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_066807930.1"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HD"/>
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        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
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        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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            <end position="596"/>
        </location>
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            <end position="597"/>
        </location>
    </feature>
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            <end position="63"/>
        </location>
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            <end position="516"/>
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            <end position="907"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
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            <begin position="925"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
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            <begin position="425"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="930"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="982" mass="108994" checksum="801F119F76DAA908" modified="2025-10-08" version="1">MGDQQPYVTLRTRRPTDGNSMSSGDSAVRGEVMHSIQRRNRSAPLTSTQYGSSVGDDRTPSATHDISRVSYHVKHLSDFAKSLEDSAARAFPNRGRSQRYKKVQALLLHWRSDDLFVLPELEDLEQCLREDYSFDTDTFAIPSDNSHLELMMRVGSMIKEHESTDTLFIIYYGGHARIDDSRQSTWCAARNPDSPWLQWSAIQTLLERSLSDVLILLDCCAGAASATFPNGNSTTETISASSWDAIAPDPGRYSFTNALIEVLQEWKHRTYSAAMLHAELPALRCPVCSVKICGHPRPPQEPEGDVSTPTGRSGGPPELMPAEPTEDVPHVMISLALEDNQSLDINAWESWLAAFPAIAKYVKVQGVFKSHSTLMLLSLPVMVWDLLPENLATNFIAFIRSNNLAIPKEAVPQSVETDVRVPGSETESGSIFSGTTMMTGARNQGNELLQGIVGPNSQDAGTAAFTRAPTSFSGGSRFQTSPPTSPSSFRKEWRPSPFGPPGRHSTAPARSSNDAISRTMILNQARSSRKTYITSADNIPDRPRLAPHIESRLENYFQDDPAPTVAVKEFLASNLGIETTDIDIWFYHRREQQQVAVRLQSLSIDSQRKTQTSDGVHMILPGHLNQLLDTLLLNQMLIVDLRAPTEYQRSHIHGAINFRAPASFVQRASFDMIEHAIADDGSRDTFRQWSEFKCVVFYDRHIEFAWECPTADALIQRFKAQGWSGHGFIPKGHYREFSASFDKHIGGSRMSAEAAKYLESLSERSMEKQVCLFIGPDRDEVEADTYSQKDNEQDYSDWLRLVKDDDRAASTELVPAVKAERMDAMAQHQKDLEDEFERRLPSLYRKALDLGLAAQENGPVENWDRKAPMVEHLSRGLEKMQEAGGGTGSPGNGDARHGLPSYPEKSRDAHFTADDYDVIDADHEHLPSDAAYQQKAAAAGVGKAPSYSSDDPPGSSGDTQQKKGTSTGGRGRNLFKMLRSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X141</accession>
    <name>A0ABR1X141_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-dependent bile acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_004099</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_066808414.1"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ABC1_TM_dom"/>
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        <property type="entry name" value="ABC1_TM_sf"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="3"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
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            <end position="103"/>
        </location>
    </feature>
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            <end position="552"/>
        </location>
    </feature>
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        </location>
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            <end position="1159"/>
        </location>
    </feature>
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        <location>
            <begin position="1194"/>
            <end position="1410"/>
        </location>
    </feature>
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        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8089138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1411" mass="157085" checksum="ABFB658DADE9A927" modified="2025-10-08" version="1">MDVSRSSMAQAAVAGGLALVYMGSRLLPTRPLWLQIFAKEPGCNYRFGHSPSPNTWRCFETTPWVVSIILTLVQRPRKTPKTLLLLFLTSLVGTVVASIATQTRADRTSILHLGEICIALGGIAVILSMPMRDPLIGNAGIAGKSDAATVELRSPEDDVTLWQWMSVSWLKPLLRKGYRKQLDDGDVWLLPYEFQHDRLHQLFGALQGSLIKRLMVANGLDLIIITFLALVESAANLGTPMLLQRLLASIQSATSPRELSIAFAVAILAVRLVASQSGVFSLWYCRRAYERSRGEMITSIYAKTLTRKSQGFTPDEKDPSHVNGNELNGEEPEPGWFARLLARLPWRKKDVKYSPIKAAPPPATMGKILNLMRNDCYEIAQRFWEFGSLFTKPLQFLVSLGLLWLLLGWSCLVGIAWVVLVQIMNALFVRRLIVNERLRRAATDKRLQATSQFVEAIRHLRWYDWQSEWLKRIMEQRNNELFLKIVTGLWTVGISTINISAGMLFPVASFFAYTYLAKQSLTVDIAFPALQLFSMLETSLRELPDLITVLLNASVAIERLESFMREPDKEEGESSLMPEDIEFRDASLSWPGMHDTVLSDLNLRFSTGLTVVYGQVGAGKTALLQGILGELDQKTGDAVLPTEMIGYCAQAPWLQNMNIRENILFCAPYEPERYRKVLEACALTQDLAGFKHGDLTDIGEGGVGLSGGQKARVALARAVYSRSRILLLDDPLAPLDHNTAESIVQKLFRGPLFENRTIILVTHRIDLCIHVADQAVEIHDGKARVLQPDEVPQNVIESEHNLAEGEEDQHSADAVAEVDAAIPDKFIEEEYRKDGGVVLSVYWTYIKAGKLYLWAGLISLFALLRFSRLFSDWFLKAWTEGYKKDQAHGGSVQANAQLDDSFGSGLFKNLPNPQDDVSPWLFGYLAIGLLNTLVFTFASCNLLLILYIAAKSLFIRVLDKVSNATFRFYDVTPVGRLMNRLTSDIGMLDGGVIGPLQNFVFNLLTFLSCLAVIAAATPLFFFFALLMTAGFIYFFLEFLPTSQSLRRLEMVSLSPLMSNFGILLEGLATIRAFRSQTHFQNRNIVIVDAFQKMDHFYWSLQAWLQYRFDTLSAFATFALTLIALHRGLSPGLTAFVLLTAARFVEATHALCKQYGQLQMDFVSVERVVELLDLEEESSGDLVPPTAWPAYGDAIEFDAVTMRYAPHLAPSLSDVSFTIPGGATCAVLGRTGSGKSTMALALLATLKPAAGRIRVGGLDLADVDVHTWRQRISFVAQDPVLFPGTLRQNLDPLHEHGDDECVKVLRRVLGADWSLRSHVEAGGKNLSQGQRQLVGIGRAVLRRSPVVVLDEATASIDKKTAMAIQEVLRDELRQSTVITIAHRLEAVKDVDYFIRLDNGRVVEFGPARSQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1J3</accession>
    <name>A0ABR1X1J3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672198.1">
        <property type="nucleotide sequence ID" value="XM_066808580.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041640"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="153" mass="16671" checksum="2A277E4EDF23F6CD" modified="2025-10-08" version="1">MIKAQWFLSDGWSLSEYGDIQNNYVYEALERLDDWRLKLEERARVDEANIPAYLARMRQADQDGENKSQTGSSSENDDNQSQSTSAETPDVVQPTLSQEDSSGEDGSVEDPSALVPNVDTSHSALSQQDSKLGEADGPISGAHSLPTPKPSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1U5</accession>
    <name>A0ABR1X1U5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">C-5 sterol desaturase desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004351</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672284.1">
        <property type="nucleotide sequence ID" value="XM_066808666.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041726"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="66"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="242" mass="27778" checksum="F6F51827C53BBEBF" modified="2025-10-08" version="1">MDIVDVVFDTFVGDYAWAKLLPARPATYKVPSATNASAAQAFSIEPSPAAHMSAGPGLWHNIIQFPFFLLFTDFFVYMIHRGLHHQLVYKTLHKPHHKWIMPTPYASHAFHPLDGFEQSIPYHVFPFLLPLQKVSYVALFVLVNLWTILIHDGEYVANNPSFNGAACHTLHHYFNYNHGQYTTLWDRLGGSYRRPNAELFREDQKMSGREWNKQVQEMGQMIVEVEGKDDRTYDPAGAKKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2A9</accession>
    <name>A0ABR1X2A9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nitrate/nitrite transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004518</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672451.1">
        <property type="nucleotide sequence ID" value="XM_066808833.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041893"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004737">
        <property type="entry name" value="NO3_transporter_NarK/NarU-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00886">
        <property type="entry name" value="2A0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="503"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="27"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="532" mass="57124" checksum="15C9AB6378AACC37" modified="2025-10-08" version="1">MKLSYLWAAPEINPITGKARSIPVLNLFNVYGRVFFFSWFGFSMAFTCVAYPLSRRSSADVLNSDCFLGVLTHTIKANLGLSSAQVANSNIVSLCATLLVRFVAGPLCDQFGPRWVFGGLLLVGAIPLGLAPLVHDATGLYISRFFIGILGGSFVPCMVWSTGFFDKNIVGTANALTGGWGNAGGGITYFIMPAVFDSLIGRGYTPGVAWRMTFIVPLIITILTGISLIALCPDTPTGKWSERHLHAQQNLHTHGVNGVVENNLVDVPGSIVDRVSSKTSGVQNAKEDAKPQSPAHHRNWDHEAACTKEEMLETAHGETVVKPTLKESMRVFLSPQSGFHMFTYFCSFGGELAINSVLSSYYVKNFPSLGQTNAANWAAMFGFLNFVTRPLGGAISDFAFNALGRSLWAKKIWIVVCGCLTGLLLVVIGQVDSHHQSTMFGLVALMAIFLEAGNGANFSLIPHVHPHANGVLSGTTGAVGNLGGVVFAIVFRFMDGGTNYAKALWVIGLIHIGLNLMLCWVPPLPKGQIGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2J6</accession>
    <name>A0ABR1X2J6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004606</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672539.1">
        <property type="nucleotide sequence ID" value="XM_066808921.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041981"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103:SF3">
        <property type="entry name" value="ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="325" mass="35007" checksum="3C9433503031557C" modified="2025-10-08" version="1">MSKQHILVTGAGKYTGFIGQLLTTALLGSSAELQLTLTDAIEPPIPSASSQHASRITAAKSDLTDTQAISSLLSTKFTAVYLLHGLMSGAAEAQMELGWKLNWDSHRAILDHLKKHNPGVVTIFTSSLAVYGPASPSEVITEMTCPIPMSNYGSQKLMVETYLNNLSWKRLLDGRIVRLPTVIVRPGAPSAAASSFTSGIIREPLKGQRSVLPVPRDLELWVCSPETVVKNLVLVKDVNNSAFGITRSMNLPGIRVTVQEMLDALEAVGGVEATSLIDESPDPKVFGIVESWPANFDTSYAKELGMKPDVALLDTIRAFADSLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2Z9</accession>
    <name>A0ABR1X2Z9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RhoGEF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004757</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672690.1">
        <property type="nucleotide sequence ID" value="XM_066809072.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042132"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF159">
        <property type="entry name" value="LD03170P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
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    </dbReference>
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        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="235"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="784"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="790"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="853"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="896"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="928"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="943"/>
            <end position="955"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="980" mass="108942" checksum="E5BF3A9B37BB2981" modified="2025-10-08" version="1">MAALVLSSEPPRFRSCSASDRAAGSWAMPASDHHLSIRPSRTNPDLSDCGAVFPLTTSEAWKDLDNITALGLSLHAEGDDESPASNTDIPQINFGDDWHLYEDTKSPRAPKPFHRWIKTLQRRAHRPRTQRSGDGSSGSQELFPPSLGDNVSSLRHRKSSSDSSFGYVAGIRSASISLAGSAITRSKRNTVRSSRCSRTERSSRASYSRTRFSEESTRCERTVSIDPAVMERQLQRRRIIEELISTEESYIGDIKFLMNVYVTILASLPTQQQGLRSSINRNLTDIVELHEEILGELHRVVPNSEYTQLQQVVQPAHKPTTRPNHQRWYSLDSVPEVKDGTPWLQDIPGMIAEPTIAADVAQVFGERMYRFFVYEEYGAKYELMIKDVASTHRAMPQWETYQKGLEALAASLGSANHHVDRSRKSLTIGDLLVKPIQRICRYPLLFAELLKHTPVYDCPNSHAQIENVLVRLREATAEINRATDDPSVKVTVEKTWLLQDRLIFPDQSFDTNTKANVRLLGQIQLCGALHVCWQTRKGVKGQYMICLLYRDSLCLATAEGLNQVYAIQACIGLNTIKLEEADNGRGLQCHTAPFSWKLVFEIDHQLYEIIMTACTPKEEMEWRTRLTGLIPNEPHDHPEAPLCSSLSLDIKSLGTVFGKPGTVARRLSIHRATTVGPKSSLCQVILKNTTLLRDPSGSGSVTPINRSQSLLTTNSRIPVLSPGRGERARLEALLADVWSRAALPFPGITNRSKSEYLVRNSASAMKRKLSVASITNTFLKRTPSTASMNKAREKLVDKTSGRASHEESGGLVRNAASSPTLDCDFFTPELSLEGDFDYVQGRLPVICDEAERASSSSPNFSATDEASAQGTVRKTSPMRLEPPPPKQRQQDETAMSLLTSPLSTSPANSLRPSRTITQSVKSLSPASTDRRKENVQHHVEEPTAQSPHETVSTLKPGSKWTKVGMLNRSRVTGGLRSFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3C4</accession>
    <name>A0ABR1X3C4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_066809167.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042227"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="UPF0390"/>
    </dbReference>
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        <property type="entry name" value="DUF2462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="95" mass="10145" checksum="A38D4D6AB6D9FDFB" modified="2025-10-08" version="1">MAQGTIKKPAAAPSFKATKSDAGKVRKGARMHNKKKATNADRVQKKLSSGLVARTEKLLGERAGHLEMIGKGRDKTGKKKKAEEAKKAGGSRKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3T2</accession>
    <name>A0ABR1X3T2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672955.1">
        <property type="nucleotide sequence ID" value="XM_066809337.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042397"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="248"/>
        </location>
    </feature>
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        <location>
            <begin position="298"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="420" mass="44384" checksum="20462A6ABB2082EA" modified="2025-10-08" version="1">MAVFSLFSAGVVERASATEYYHGGDHGHRTNITAKVLPGGAGGPGRPGSRPRPGLASPVINPAPDRPPPPSPPLPSPIKVVGKTTTSPKATTTVVQETQSLTQVTTTPFGTTTQITLTTAEPASSTVLIASPPLYISTGFSSTTGLVTSASLLSTSTSISSTALGRSASPSESPVSDPMAADNDNAANDRTRSPLFNRGITPIHDDEIATWKINRTASEKSAGRYTTRNSTTQDSTGHTHKKTPSQTPSLIQYQQPLGKQSFDSIAQSPRSFIQRQSMDLPQSPQSVILAKAPNARSGLTDQAIPGDDPFLPAPKRQPSRLHKLPSAPPPTSGNMRTRSSRSNSMRSFGDVWHGDNTGIPRSPRPSTEAHNTITRTTSSRIYSSSTIPPRMSLSNLNEPDHFNGLSPPPLHSTEIGRAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4B7</accession>
    <name>A0ABR1X4B7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">prephenate dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_005197</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673130.1">
        <property type="nucleotide sequence ID" value="XM_066809512.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042572"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04905">
        <property type="entry name" value="ACT_CM-PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13532">
        <property type="entry name" value="PBP2_PDT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022">
        <property type="entry name" value="PREPHENATE DEHYDRATASE P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022:SF19">
        <property type="entry name" value="PREPHENATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="235"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="198"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8090236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="319" mass="34135" checksum="7BDCE3C3C3CB740F" modified="2025-10-08" version="1">MSAVKKPVVCFLGPVASYTHQVHAFDTTQSGRATYGVVPFENSTNGSVVFTLDHFADRQGLYPDLSVCAEIYLDVHHCLLGRSPPDDDDDDAGAAGPEGDPRSRPLVPLTRIERIYSHPQAFGQCNRFLSAYLKGIETVDVSSTSRAAELVRDDASGTSAAISSAAAARLLERDGVEVLAYNIEDREDNTTRFFVLRAGTDDSTTPGPDGDSAAKGPSSSSSPGKQTPAKTKSLLSFTVPHAAPGALADVLSCFRAAGLNLTSIASRPSLLAPFQYVFFVEFEGHRSVDPEGKVARVLEQVGRVAESARWLGSWVNQRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4G3</accession>
    <name>A0ABR1X4G3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell wall biogenesis protein Mhp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005269</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673202.1">
        <property type="nucleotide sequence ID" value="XM_066809584.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042644"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052410">
        <property type="entry name" value="DRC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107:SF2">
        <property type="entry name" value="NLR FAMILY CARD DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107">
        <property type="entry name" value="YNEIN REGULATORY COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="221"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="956"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="283"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="998"/>
            <end position="1011"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8090308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1157" mass="125680" checksum="C72FD8D66999FE49" modified="2025-10-08" version="1">MECLVVTSGQSATPNQNPPSQPLETSTPSKLNGKTPVAGEPPAQSSPTPTTAPAAKPVPQRPSVGRGGQNDEKKPPGANGTPPQRRGSWFAKISSSFSSSPSPAQTASPNSQEQAENDDLTPLPKITPSKNAVLPHGSKPSGEGPYVPAPPRSGQGSFLHVFRRLSSGGAAPPPGKNNHGLVERRVLNVDKNRERPRLNELNQAKLRRVAFCVDVEIAPMPKYADSDPSGNKPAEKAQKKKLAEAQKEANGVAKAPGEQISKEPPTEKIEALNGQPPAPIPIDDTKPAEKETTRKKEKKKKSEAERKAKKEQKRKEALEKGCIPMELHYDSDSSSEEVAIPKGPQKPQSTPTTNPGRIYRRCCQLRETDILTKITTQLPKSTDNGVVEKLDLTGYFMSREDLVTLGDFLAVVPVKEVILENCGLTDDGVRGVLSGLLSARKPAARQHRRSLSKPVNLTRQGGVVERLVLRNNKLGVDGWKHICLFIHMCHSIKYLDLSSIPFPALSQEATKSPLSHHFHLHNGANSAGSHDISALLSNALAERLAGPELELLNLGETGIATTQLAALVDGILKSGVTRLGLAHNELDGPGLQQVARYLRDGKCQGLDLGGNNLRDNLEGIAEAINEDGTMWALSLANCNLKPGSLCKLLPKLTKVKNFKFLDLSHNHDLCDSDPSAIGLLRRYLPQMETLKRVHLADVNMSSEQAIALAEVLPEVKHLAHINLLENPKLVFLADARTEDTQEEACALYASLLAAARVSGTLVKIDIDIPSVESGEIVKALANQALAHCLHNVHLVPDISDHVPGEQVPADINKYPDVLRHIVGNPTDPATIDGAEDDQSEAADEDYVIGGTGVVKALACVLKNVGDDSRRQSGEFMREIETGHIGPRANMPAGKAKDMSKHLLASARKIHARLQPALTRAKAASSRDMNNYNRLVFLNTTIEGIIKRFEDEFPETRVDAESTAKPAHTPEHAPSFSSNDIDTVAVSDNEDLETELKSPARSRSNSIMSSTSKALVEEEGRALRVGHKFRRGFLRQANLDLLTCSEVANEPEQKRMIEGLVDDLGPDGEDLRKKAAEQGFVEMFQQEREEIFRRLRDIDVEYWDRFIESQEKARANVQVQVGGSGGATTTTAPSKDIIKDITTAQREPSQCDESAIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X872</accession>
    <name>A0ABR1X872_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673585.1">
        <property type="nucleotide sequence ID" value="XM_066806289.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039349"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="127" mass="13333" checksum="431DC63A4FB88204" modified="2025-10-08" version="1">MGQEADADAATGRLDWFVRVLCCWELAVPAVRNFARAALLIEEAIFQKTRFEAAERRADPEAAKKENKAGKDAKDAKEAAEPLVAVAVAVCLLAIGVTDRGNVALAERAASGAGASRLLVAATAPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8F5</accession>
    <name>A0ABR1X8F5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673681.1">
        <property type="nucleotide sequence ID" value="XM_066806385.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039445"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8091709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="178" mass="19717" checksum="2F84FCFD7C576ABB" modified="2025-10-08" version="1">MTVNLGPYGALHDTAPNPQADGLGYNPRPLKRDVGPAMNMRYANASTVWNLLHKPNIKEYRLLLEGPFNTGEIGPHGGGHYTINGDPGGDFWTAPAEPAFYLHHGMMDRMWSLWQAIDPETRHVDLDAGAYGHRTWNNEPPSPLTSLDDAIDMGYVGEGSVIRDQMSTIDGPHCYLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X949</accession>
    <name>A0ABR1X949_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aminotriazole resistance</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002310</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673921.1">
        <property type="nucleotide sequence ID" value="XM_066806625.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039685"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17476">
        <property type="entry name" value="MFS_Amf1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF1">
        <property type="entry name" value="LOW AFFINITY AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="71"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="550" mass="59126" checksum="74CABE233D9347B8" modified="2025-10-08" version="1">MTTTTNADDVGTNHGRLSPKDDERDLGRDSGLDSSPEDDADDTSTVDGTGPEATRVSTNLSIAETISLPHELLLVAVVCLAQLYTQAALGNTIGILKIIGRSYGISDPAELSWIIAGYSLTVGTFIMFSGRLGDVYGYKPLFLIGMAWFSAWNVVCGLAIYSNHVLLIFARVLQGIGPAICLTNGLAILGASYGPGKRKALAFAAFGATAPGGSILGAVFAGLFARHWWPWAYFCFAIVLALSVVLSYYVIPSRPSLMGRPRETWPRGFWSVIHELDLAGAATGITGLVLINFSWNQAPLSGWSAPYVYVLLLIGVLFIAAFFLIEIRYAQHPLIPFDALSVDVSFVLAAIACGWGCFGIWIMYTWQFFEEFRGATPLLATAWFSPVAVSGCAASVFTGMLIHRLGPAVVMAAALLFFTAGITLIATAPVEQTYWSQAFVSMLVTPWGMDMSFPAATLILSNAVHRKHQGIAASLINTVVNYSIALGLGFAGTVEYKVNNGGETPEDRLRGFHGAYYMGIGLAGLGVLICIAYLIKAHRTRRDERLSEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA59</accession>
    <name>A0ABR1XA59_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674266.1">
        <property type="nucleotide sequence ID" value="XM_066804493.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037553"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="483" mass="54418" checksum="B383648AE15351E7" modified="2025-10-08" version="1">MAFVRTKTLLRHASTSGGLAPPSVSADQVFPVHYWDHGYTNAVMNFMLRFDHRLDAGKLRSSLERLLERPDGWRKLGGRLKRNAAGRLDYHVPSRYTPHRPAVSYHHERYDDDFLPLMRRPEDPTCLEDYLSSDTPVLGLHVVTFRDATLVCLRGSHVLFDAMGRKAFLDAWALTLQGRDGEVAPLMERDPMTTLGAQEPEKTESCALPIEPYKHVVKQLRLRQFIMLGLRQVLDRILNRNAIEEARVVCVPSAYVERLRTKALKELEARTKVDSSEKDPGSPAFVSAGDTLCAWWTRHLIASRLRNARTSDQTVCIMNMLGLRGHLLQSGLVSAAEKKSAILGNLLVAVPAFLRADTLLAKPLSEVAETFRTSIKELSTWPQVEALLKLQRAAHDKKGSMPALFGDGGMHMVICTNWLKAGFFDVDFSAMHMTTDSTPTFMMSIFTILGKDACGNYWIRGTLREEYWPKVEQSLLEEVLLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA60</accession>
    <name>A0ABR1XA60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674298.1">
        <property type="nucleotide sequence ID" value="XM_066804525.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037585"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="157" mass="17751" checksum="49D125920139282D" modified="2025-10-08" version="1">MSRHNPSVTDDSRKARSRTSSQTSYSVHMSSHSPQASHINISTKRSSVHSHTKAPQPSPLKMVTTSSTAHQHHHHPRDDVSYYFLPSEADLACQGWMTPTVIDDDDLMFGGKSLSEWYEEERMQAASPPEEERRGRQRVSNLVDSHRLTTRLENPGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAF4</accession>
    <name>A0ABR1XAF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">nitric oxide dioxygenase</fullName>
            <ecNumber evidence="2">1.14.12.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_000242</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2 nitric oxide + NADH + 2 O2 = 2 nitrate + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2 nitric oxide + NADPH + 2 O2 = 2 nitrate + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674330.1">
        <property type="nucleotide sequence ID" value="XM_066804557.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037617"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08922">
        <property type="entry name" value="FHb-globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06184">
        <property type="entry name" value="flavohem_like_fad_nad_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009805">
        <property type="entry name" value="PRK13289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00410">
        <property type="entry name" value="PHEHYDRXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0216">Detoxification</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Globin" evidence="10">
        <location>
            <begin position="10"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="161"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8093557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="420" mass="45408" checksum="F32F3496A27AAE74" modified="2025-10-08" version="1">MAVTGKVSAPLTPEQIAIVKSTAPALKAHGEEITSLFYKNMLGAHPKLHNVFNKTSQETGAQPRALAGAVFAYASYIDDLGQLSDAVARIAHKHVSLMIRADQYPIVGEHLIAAVAAVLGDAVTPAVAEAWTAAYQALADIFIGLEASIYAEQEKSAAGWNGWRKFKIAKKVPESSEITSFYLTPEDGKLPLPGFKPGQYVSVHMHVPELGCMQPRQYSLSDVPGQDCFRISVKRDAGKEGGVPGLISNRLHSDYNEGDVVEITHPAGTFSVESKTGSQSPIALISAGVGVTPMVSILNSTVAEGSTRPVSWVHGARSTEVQAFASHVRDVCERNPNVKATIFKNNVKDDEVKGVDYHFTGRMDLEKVDRKQGLFLDDPEANYYICGPPVFMRDIQQYLVKAGVSESRIHMEVFGVGDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAN2</accession>
    <name>A0ABR1XAN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674501.1">
        <property type="nucleotide sequence ID" value="XM_066804728.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037788"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="117" mass="12776" checksum="DBF0CC014AC1FF9D" modified="2025-10-08" version="1">MDQCDWVAALGVCFQIVGHSRLESSSPEPRYHDECAVMTMEDIAKSCECAGNIHHAIAWLKQASVSGGIVWGQSETLAHVHDKLRELLKQAGMYEELEIWAPSADSSESRNAMSGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAW6</accession>
    <name>A0ABR1XAW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7580 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000407</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674495.1">
        <property type="nucleotide sequence ID" value="XM_066804722.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037782"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056002">
        <property type="entry name" value="DUF7580"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186:SF4">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24476">
        <property type="entry name" value="DUF7580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7580" evidence="3">
        <location>
            <begin position="215"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="318"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="586" mass="66612" checksum="36486AECF276DCA8" modified="2025-10-08" version="1">MAEIVLGVLPLCLSAIKGSIAVLRTLKAVRNRKSEVERLKKEFETQRIIFLDECEILFQECLDDDVLAGELVKDTTHPAWQKSQLDKQIKTYLGRRLGRYEETIKDIQKYIKELSESLHGTAGDSQRPDVKVCLWKLRKPLQRLIGIFQLKKSEVTREELNVIRNKSKYESLIENLRKSNHELKNIREMASRRNESAPPPSHQAEPLVSLPSSYHTVAQYSASFYRALSETWSCKKPKHTNHEARLFLDCKNDTSFRVVLRCRTSSTQLANDTWVESMVLSESHELVKIPTPLGFQTDEKWPRAVEVRRLRDKDRRSTQQTGVSGTSKSSLLTAPVPINLGLSRDLCAQLCTQTKSAMCSRYLDASDHIRHSIRPFCDEKCDHKWCLDQDSLSDPTQLDSILDVTVEQSGLGVVQQLQLALRLVKGILQFASTPWLQALWHLKDLSYFQMKNGLSTALATVHINSDLTQQNHPRPKSINLHDTLLMALREHGIDNLTLFSLGMALLQIGCWRRLPIDDIGEVRRIAECNLGLGLAYQQITLQCLECNFASSKDLSNPKLQNAIYQHVVCKLEESINVLGGDCDVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB35</accession>
    <name>A0ABR1XB35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Telomere maintenance protein SDE2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_000551</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SDE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674639.1">
        <property type="nucleotide sequence ID" value="XM_066804866.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037926"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051421">
        <property type="entry name" value="RNA_Proc_DNA_Dmg_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053822">
        <property type="entry name" value="SDE2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024974">
        <property type="entry name" value="Sde2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786">
        <property type="entry name" value="SPLICING FACTOR SF3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786:SF1">
        <property type="entry name" value="SPLICING REGULATOR SDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22782">
        <property type="entry name" value="SDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13019">
        <property type="entry name" value="Sde2_N_Ubi_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sde2 ubiquitin" evidence="10">
        <location>
            <begin position="8"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="SDE2-like" evidence="11">
        <location>
            <begin position="89"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="205"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="208"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8093866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="283" mass="31075" checksum="815C29F09BB91035" modified="2025-10-08" version="1">MASTSHLNVLVSTIPGLGSKTLSLRIPRDETVADLYEQIDERLTVDACKRLIVTTQSNKQLSYGDVKLASLLPQDDDFLTLRLSAPLCGGKGGFGSQLRAAGGRMSSKRKKTGRENDSSRNLDGRRLRTVNEAKALAEYLAIKPEMEQKEREKRMERWQKIVDAAEEKEYEIKHSNKGRLDGKWVEDKEEAAERTREAVLAAMKKGTYQDNLATSHGSTSTEAGDLEDSSEQSSEGEVAEASSSGSKSATPPEAADKGKKPVHRAFAGFEEDDEFMSSSEDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC30</accession>
    <name>A0ABR1XC30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674957.1">
        <property type="nucleotide sequence ID" value="XM_066805184.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038244"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="559" mass="61937" checksum="8263B113E0DC71F0" modified="2025-10-08" version="1">MVPASTNIPDIARPEPCRFQGSIKPAPVPYQAAMEGSDLSQRRSSSDKSSGRSSFSSVRENDSDLAQTFTSTKVSSYSQPAEAAVVEDDDPTTHPPPPPHCCCLEDRVVRSPASNKPTPSKLPGRPTAGQAPIERLPLELLGPIIDLLVLDVPPNGISARNVDLMSLLLTSKTLHTATLHALYRNITIPHSRIFRKFLAHCLEFTPYLREFLAQEHIDDEIDENVLRKLFLDLPRLQAVDFTGCSSGNFKAAMSAIPKFEWPVSLAISRLSLHKCINLPSAVFETLMPTLGNLTHLDVAGTRITDEALMSIPHTARITHLNLAKCALLSAEVVIEFLATHPAVNGSLVFLSVASDARSHQLFDVEDVTRLLPALPPTLRSLSLKGSKMDDSHVNLLRPLTKHLEELALGRGLRLIDIDRLFVPDEDDDDVQMQLDWVPHTLKYLDLSDYSAAELDFSTLFSNSMSIMKKFSAPLEVVEVTDNLYSRLSKSPALQRLGWMVTEFGSRAWMVRRHSPEDGPRDSGLRSWKLGASFWGMRKIPMANAEVGGMYGSYMFKRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCA9</accession>
    <name>A0ABR1XCA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CWH43-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675072.1">
        <property type="nucleotide sequence ID" value="XM_066805299.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038359"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="2">
        <location>
            <begin position="20"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="269" mass="30042" checksum="676F2B4B6FB93EB1" modified="2025-10-08" version="1">MATVPLWPRALKHVSLTPYLWLFPLVAGISWFTTISILLARWLALGQPRYPGQVNPDVPFISDIAAFTLKPVFVAGCTVTGLGFAGTVFAVHHVRYARAFYGLVDDVAWRQNTSVLALVAGLAAAVLLFFLSIFDTVDAHVRHQYLLMGTFGGLGLSAVLTAAVWWDQTWGPAKFSGLRRWCLINTGLMACQVLIGLSFVVLMYSGRYRPAGFLEWTLTYLGSFWLLSFVGYTRFRKGIDPKLPETWNGDHFLLSGVKYRSVLRVQYEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCC3</accession>
    <name>A0ABR1XCC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldose 1-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000975</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675063.1">
        <property type="nucleotide sequence ID" value="XM_066805290.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038350"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09019">
        <property type="entry name" value="galactose_mutarotase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047215">
        <property type="entry name" value="Galactose_mutarotase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091:SF6">
        <property type="entry name" value="1-EPIMERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091">
        <property type="entry name" value="ALDOSE-1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046341782" evidence="4">
        <location>
            <begin position="22"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="411" mass="45193" checksum="0B95A399CE2DD42D" modified="2025-10-08" version="1">MHLNAHLATLGAALLLPAASAQTYGRGSKGPGPDKDGLYWIKSEGLQAAFITYGASLTHLLVNDQYGIPRDVVAGFDNATYYEVDKQHNHFGGVPGRYANRIKNSTFELDGESYHISPNENPTADAPLGADTLHGGKDGWDWRNFTVVAHTDDSITFTIVDPDGKEGFPGEVVSYITYTVTDSTWDFKMVALATTKKTPIMLSSHVYWNLDGFANNETSTVLNHTFHLPYSGQRVGVDNILIPTGDILANKEGSVNDFWSAPKQIGASFDDPELKGNCGFNCTGYDNCWLVNRAQNGPYDWRSDGYVARLHSAWSGIQLDVYSDQEAFQLYSCNGQNGSVTLKTTQGLHDNADFPRTIPQYGCVVMEVEDWIDAINQPAWGRQDKQIFTPGGDPYVLQASYRFSINGTSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD58</accession>
    <name>A0ABR1XD58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-1-2-galactosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001237</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675325.1">
        <property type="nucleotide sequence ID" value="XM_066805552.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038612"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF10">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="35477" checksum="3A386BF01AB1A66D" modified="2025-10-08" version="1">MHFAYPPRKSSNPPPFLPRSSRISTLRRNRLKLVAIAGLSIIFLLWLFSGSKTKASPKRIITGTPPVVIVTAFEEKAVGSEFIRNAKSNRREYAKMHGYKTHLVSSGDYDLNGSPLSWAKVPAMRHAMAKYPNARFFWYLDQNSLIMNPSLKVEDYVMGARKLETSMIKDLPVVPPDSIIKTFSHLKGDDVSFVLTQDKEGLSAGSFIIRNGDWAEFFLDTWFDPLYRSYNFQKAETHALEHIVQWHPTILSKLAIVPQRLINAYSKSSQGEQYKEEDIVVRFPGCITGSPSECEEEAKRFLPQWQKAFGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDT7</accession>
    <name>A0ABR1XDT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001458</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675546.1">
        <property type="nucleotide sequence ID" value="XM_066805773.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038833"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="346" mass="37567" checksum="0BD2283FB75D1507" modified="2025-10-08" version="1">MTSPATEEVDLVIVGGGPTGLLCAVLARRLGLSVSVIDEKPSTLPAGRADGLNARTQQYLQIAKVLYDLQPKGVKCNTSSTFANGEFQSRQSSWWTSLEHCLEKNMLIVGQPEIEKVLLQKLRTEHSTAAAYLRFDHRATSISEDADGVTVKSEQVTAGDGDSNGVTTRAKYAIGADGARSTVRQALDIGFEGTEPEMVWAALDTVLDTDFPVCPEIVSLQLAGQCRVLWIPRERGMARFYIRLPEEEEEEEEEGGARDHARGGRGDDSAAYGAVPGRVCADGVVWDVRRGRVFLAGDAAHCHSVNGAQGLNTGIADAFGLIWRIALAYPKMKPMSSPERPRRERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDY5</accession>
    <name>A0ABR1XDY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675683.1">
        <property type="nucleotide sequence ID" value="XM_066805910.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038970"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="9556" checksum="1B4CD751501BEBA2" modified="2025-10-08" version="1">MSSTSNMASRISSDSYDDIAAMKDSPSPNPSSKSSSSSRISAAMKKAKAKLSSSSTTPEEKAQKKAAKSARHSQAFKDTLFAYEVLAMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEB2</accession>
    <name>A0ABR1XEB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001642</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675730.1">
        <property type="nucleotide sequence ID" value="XM_066805957.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039017"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="248" mass="28799" checksum="2330E919ECAC2C01" modified="2025-10-08" version="1">MPRLSDISYSREATIAAVRDYYQFLRELGYLGKTDEVIELLRHLPYIRNDGDVETPQAAPGTHFVDWARLATRNWDRESMLLATDGGEWEHVPPHVVGLALEARWSFSFNLDTELGVIYWIKCPHAIECDTRVEPVLDDAMDYTPEEELGRRRDGPAWAVPDFFELLKGEFRQLNFVPVGPRRVDDDYSNHSGETGDGSTDVMRKLYRDHGWPDLDRYRKGECLEALRNTLREKYPDLLEDDVDYDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UPZ5</accession>
    <name>A0ABR1UPZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF803 domain membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_015220</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8060999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660419.1">
        <property type="nucleotide sequence ID" value="XM_066819534.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052594"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF65">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="73"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="366"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="482"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="581"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="414"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="442"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="482"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="500"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="605"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="656"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8060999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="694" mass="75085" checksum="7D44F618D248070B" modified="2025-10-08" version="1">MPVMPKSYDASWALAGSGDNSGPRIGNWSSLIGIITSIVGNILIALALNVQRYSHIKLQKRKTEARERAKEALRRAQNGGGRNGYGAINNSIADSDHDAGEEDDVLESRPLMHSTDSGRLVVERHLRRREGSRINISQVTIMVAGPGAYDAPLFFGEIFRARDFWGVVIAVGGAVTVVLSAKQEETKLEPHDVWDAITTMEFEIYMGVSIFLIIVLMWASPRYGNRSILIDLGLVGLFGGYTALTTKGVSSMLSSTLWRAFATPVTYGLLVVLLSTAVMQVRYVNKALQRFDSTQVIPIQFVLFTLSVIIGSAILYRDFERTTLQQGIKFIGGCVLTFFGVFLITSGRPRHDDEDELSDDENIEETIGLTEQETNGDRSAKPSNHHRARSSVSSTVSSRHSSRRASRISFAESGVNNPLNSVLHNTGVPSSRKPEGSVSRTSLPLESSPLLNNPWRNSVEDRPPHPGFMPTFSDDSVVTIHSATSTNTDPSPTTGFGAAPSTTTYPTTNTPSERPTTPRPSFSSSRPHSHHFSNTIMSPSPLSSTITAVVADTLLRDDHTMPRRKSIRRLRPTIRSSLFVSQDEDDLEAQESGALRPTATEPNLLHSTAPTTPSAGAVADPMMAAGERQGLRGRARSVSNTLGDFFGRKSKRRNTNPETSSSGNSPAGERVAPVATTTAADNSGPGAQRGGATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQC7</accession>
    <name>A0ABR1UQC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660527.1">
        <property type="nucleotide sequence ID" value="XM_066819642.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052702"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="419" mass="46240" checksum="45B96A07AE0FC088" modified="2025-10-08" version="1">MSAIQTSARAAIPRAARQLRTSRIPQQTRFQSTTAGPSNASSSSSSGGGAATSFASGMAGGVASVAIFYMLYSNSAAGKVHSAISKTATEANKTYEQAAQKLQEKTPDADQAYRYVKEFCYSYVGWFPGGRQYVDTAFRDFETVREKNKDEADKLVNDAYKQFQGLAKSGLSLETARKAYDMLADLSKKLANLAGSSIGDLMDNHPKLKEQLGGNVDQLKQLGEQYGPEAKKQVDETWAQMADIFKTGFSAASVDKARKLIQEKTEKVQKLGDEAWKKGLEQAKPYLEKYPEAKKLLEENEEALKRGNTAELFKNLSASLEKKDLSGFEDYVKKTVDQAKSKGQQAGKSFGLDLDSYFQMIPNGGEILPKLKQLKEVAEKHQEEGQKLLKETMDEVKQVLDKKSQRAQEIVDKAKKEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUB2</accession>
    <name>A0ABR1UUB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mago nashi protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014616</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mago nashi family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661118.1">
        <property type="nucleotide sequence ID" value="XM_066818930.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051990"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11295">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1560.10">
        <property type="entry name" value="Mago nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004023">
        <property type="entry name" value="Mago_nashi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036605">
        <property type="entry name" value="Mago_nashi_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638:SF0">
        <property type="entry name" value="MAGO HOMOLOG, EXON JUNCTION COMPLEX SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638">
        <property type="entry name" value="PROTEIN MAGO NASHI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02792">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89817">
        <property type="entry name" value="Mago nashi protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="158" mass="17976" checksum="7DDFA572CDD5C094" modified="2025-10-08" version="1">MANSASSGEPFYIRYYSGHSGRFGHEFLEFDIRVVGDGRSAVARYANNSNYRNDSLIRKEMCVSSLVVDEIKRIVRSSEIMKEDDGKWPQKNKDGRQELEIRFGGEHISFETAKIGSLIDVTESADPEGLRVFYYLVQDLKALVFSLTSLHFKIKPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUN3</accession>
    <name>A0ABR1UUN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661235.1">
        <property type="nucleotide sequence ID" value="XM_066819047.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052107"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="10326" checksum="B53ABC0D0359715E" modified="2025-10-08" version="1">MKKKMRRGTLTRWPTFGGRDVRCDAMRCDGAQRELVAAAVGALAAASHKQPTRMQRMHAPPALALALTHSRSAPAAASLAKSQNRAMSFGFVFVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVX3</accession>
    <name>A0ABR1UVX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tartrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_015188</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661690.1">
        <property type="nucleotide sequence ID" value="XM_066819502.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052562"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF23">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8063091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="136" mass="14891" checksum="DD22D67C1DA793A6" modified="2025-10-08" version="1">MQGRASITADDDVSKPDTKHVDEACSKPVGVHTVATPESLRGMAEDELKKLEKKMVRKVDFVILPIMTVLYILNYVDRSALAASKVYGITKDLNMSEHDFATAISILFVGYIPFQIPSNLIITKVSRPGLCKLGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UY76</accession>
    <name>A0ABR1UY76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_015117</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661619.1">
        <property type="nucleotide sequence ID" value="XM_066819431.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052491"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF54">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046579592" description="FAD-binding PCMH-type domain-containing protein" evidence="5">
        <location>
            <begin position="22"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="113"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8063020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="530" mass="57234" checksum="94DD289234210880" modified="2025-10-08" version="1">MQLIRSVHVPLWLSLAGLSLSSNTDRNSLPTTSYQRHHMQQQQHSMDAQFDAFVGSIGLSGPDAQALKSSYGNKPADKVGAACLATQCVLGKDAVDTAPLNQTAVEANWSKANVAKPHCIVTPTSAHAVSVTIKALSFFQVKFAVRSGGHSPNPGFSSVDDGGVLLDLSKLDRMTLSEDKTILSVGPGQRWGKVYSFLDTYGLSVIGGRIPNVGVGGSFWVVSIATSTSRHDWLQLTGNAVTGGLHHFSAKYGLAADNVHNFEVVLSDGTITNANAKENTDLFWALKGGGPNFGVVTRFDLYTVPTRNIWLRLTVHALDQANDIFDAFAEWQTQGGATDSRATVITGIALNSIAIGLVAAAPGTFAPLDGLPFLQALADGVPTTLLALMDQMGAATTNAATRHDYRAASSRVDARLYKDIYAFWRARALAAREPRAPTRRWTTLVDWTDAANDGEVRAVSIDTTRQWAKLGQERGLHLPFLYQDDSSRDQNPLASYGEENVAKLKQIALKYDKTQFFQKLQNGGFLLSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1C2</accession>
    <name>A0ABR1V1C2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8064977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661731.1">
        <property type="nucleotide sequence ID" value="XM_066816039.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049099"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8064977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="432" mass="48370" checksum="8E3CC02B60FEC2A4" modified="2025-10-08" version="1">MNETGSRRPDKESINIQCVLLVDGKPAVEYTKDYILHQLALPNALLISTEATKYQGHYTEYLFSPDLKTSEELNMAGEATFCRPETPTIKIGATLASTAEIVLKRDEEAKASMKTRRGKKQAARRDERFITKYIRVGSDTTTNMELQAISNLTVSDDDTSNFSYLSRVLIDFRGGVLKHRLTKLFPIFNEVLELAKPEPFRDALRELPASYKGCHLDETARVPLSQVDMDFGTVPDPKPQTRDDLVRMFFAEYQRLDADQKALFDELKSLPFGMLNVLGVTGAGKTHVLLLILIMACNEEIDYENRFEHIDQMVADSDSDDDDEPEEVVDEVIPDEAKSNEVTSDQETQPVDASSDQQDQPVDANSDQESKPDDIFGGATFADYGGFGGFREQRGSTEERSPHGDYGTVFGKLLQDPTRAALCRRPHEHGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V336</accession>
    <name>A0ABR1V336_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012324</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662330.1">
        <property type="nucleotide sequence ID" value="XM_066816638.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049698"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046774688" description="FAD-binding PCMH-type domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="178"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="650" mass="70615" checksum="1C15257F4693E421" modified="2025-10-08" version="1">MHSHIARVAVVSLILSVVGARRLDLRKPTRAAITRVNTDSVAGAPWFEYEKLQLTSDDLDGLSTRGSKPKVAGLIGFDVGPELQPGECRTFPGDSSWPSESEWSDFGDLLSGSLIQTVPVAAPCYKDWGVYNKEQCDAIRGSFPNPYFHEADPTSTMWPIWQGRSCLPTDDPDALCTLGAYPVYAVNVSNVAHIQTALNFARNKNLRFVIKNTGHCYLGKSNGAGALSVWMHNLKDIEFLPDYQGGGSYRGKALKVGAGVTVREVYEAAHRHGVSALGGICESVGYAGGYIAGGGHTPLSGLYGMGADQALAFEVVTADGRFVTASESSNPDLYWALQGGGGSTYGVVTSVVVRTSQGAQCHVDVQFRDVSTLSNETFFAGIRVYLEYFVPFTDAGTYSYFSIIFANGTFSFQMQPFFAPNHTIDSFNRLTKPLFDQWEALGISITPNTTFYEEFLPAYNDNWSMSTPVGESIVGGTNTLPSNRLFPRANFADPAKFNATWAAVAQHLAAGRRIIGYHQAPQNRLGVDNGVSSVWRTVVAFLITGADIPPDATQAQLRQAGQDINDMMGPWRDAAPASEGGGAYLNEANVLEPGWQASFYGERYPELLKIKQRWDPKGIFYATTGVGSESWEVRTQGQGLPTQNGRLCRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V344</accession>
    <name>A0ABR1V344_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662341.1">
        <property type="nucleotide sequence ID" value="XM_066816649.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049709"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="148" mass="16285" checksum="D9E9EEEDD60A7446" modified="2025-10-08" version="1">MVFAVVDFWVAAGLFVITYVQWKEFQVKRLYGPPGTKSYTVGNIEETPAQKLHQQTQNEGCSTMSQEIWGRLKNIEDKLDAILETVQEGARPNPESSSATAASHDHEPGVEEDLSAKPPSDSDSEKHGATCNLSEGDCDGRAGYLIIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V358</accession>
    <name>A0ABR1V358_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662356.1">
        <property type="nucleotide sequence ID" value="XM_066816664.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049724"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF104">
        <property type="entry name" value="EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="133"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="395"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="63298" checksum="E92C3FD7750441B7" modified="2025-10-08" version="1">MAAHQHSLTSRPAQRWARLPTAGHAHHHHPPTPGPSRIASASLYTYKLRVPRQHGAAALVSFPMIPKGISEAAGNALTSSRRSLPRYRCASLHELANSIPRYPSMNTSPASQLWHPSRGISFSPTPAKSWSWLGLSDKAPPQAAATEESQRDASVDGGEKQCASTNSNDALATADEAAVDSPVLDPPDRCVPSDENTNDPPYPALKWRVSEPLFRAAKSAAPGTPESFWSYKMYRGPGKDGSEQPVKVHYCKSRHTTDRVCEQYFMNEKVLGFDLEWVAESTRLQGPRRNVSLIQLASPSRIALFHVACFPKEDNLVSPMFKKIMEDSNITKVGVWIKGDATRLRTHLGIDSKDSASDAYAGVHLYATLEHHRNQLNPCPPTPHHAELNLPIRFTDGSDLETSSDEELAEQPEAEDDQPQTLSPTARRRLLKAHVQSKRGGTKDAAKTTSGTEKAVRPRDARVETAEAWAAVFRKENQPTDPVEWAKSGCASLHELRAYHIWHTNKGMSAADIAGILRSPPLVTKTVVGYIWGAVRKERLPVDRRRYMAEVVQLLPEKQSRIARQALTRSSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4N1</accession>
    <name>A0ABR1V4N1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662903.1">
        <property type="nucleotide sequence ID" value="XM_066817211.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050271"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="208" mass="23103" checksum="E50145FB00AF0A14" modified="2025-10-08" version="1">MEAILNFRPTRLERAEGFLAAICMAVAATNPGPDPEFDAFFNQILRAKGLPPLPVEPTGEGELYDFLKYEPFGKARTILAVMAPASLCFVFLSPETKRAIVNRLGQVLFNQMKNTAFLFLRYWRPGNRPLVRGLPSGVLGLRAVPGYSRQQNPRFWMFFDIAACGPFSDLVMCGLYGPLWDFPRYACGSAQAFVTAAAATRLERALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4Y6</accession>
    <name>A0ABR1V4Y6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662129.1">
        <property type="nucleotide sequence ID" value="XM_066816437.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049497"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="188" mass="20096" checksum="7BACA4530B3253F7" modified="2025-10-08" version="1">MPPALFTHELLVEMLTGHPTGHLDPFPASVPLAPPASPAGNSPFLLWRRQTAYFDGGGSDDKDAMAAASAPAMERNAYGGMDGGGGGYYYGGGGGPYLSPGAIVGIVIGCIICLIILIWLCWCCVSLGGRGRGHDDRRYRRRGRDVSSCSYVRSRSRYERGRTVVVENSVCRPQPAVCNGGCRGCKYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5A4</accession>
    <name>A0ABR1V5A4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663125.1">
        <property type="nucleotide sequence ID" value="XM_066817433.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050493"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050960">
        <property type="entry name" value="AB_hydrolase_4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794">
        <property type="entry name" value="ABHYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794:SF63">
        <property type="entry name" value="ALPHA_BETA HYDROLASE 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="124"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="424" mass="47331" checksum="3F6E9649DA02CD81" modified="2025-10-08" version="1">MEWFGRANINFHASTTPIKISEKDGSPRTLLDICQETVPPCQLNPLLFNGHLQTCWTAANKEAPPVHYKRQIFEAEHSGYSGSFTVDFFTPDEADEVDETLPERTTYFSDEELASGIGSDDARPMLVVLHGLSGGSHEVYLRHGISPLLESGAWEACVVNSRGCAMSKITTGILYNARATWDTRQLVRYLRKTFPNRPLFGLGFSLGACILTNYLGEEGADCQLKAAIACANPWNLELSSKALKRTFIGHNLYSRVLGTAMKKLAETHRTEIEKFTDLSMEELTKLTYLYEFDRVVQCAAWGYPTEDAYYRDASSVDSVLAIRIPYLAINCTDDPISAAESWPVGEIKANPYAVLCGTSLGGHLGWFEIGGGRWHSKPITNFFNYMAFKADLTKIETEKKDNTRTYHAGAEFDPMRRKMAVPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5H2</accession>
    <name>A0ABR1V5H2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ABC transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_012303</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662309.1">
        <property type="nucleotide sequence ID" value="XM_066816617.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049677"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="511"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="918"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="998"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1073"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1101"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1187"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1213"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="271"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="597"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="924"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1275"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="358"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="859"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1394"/>
            <end position="1413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8065556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1550" mass="171749" checksum="E79F4ACD5A1EB5A6" modified="2025-10-08" version="1">MSAENGFLGTSAASVGLVALFTTPAVVRLVLQLRNRDAKPSDVYGDEDGKSTPEAVKAFSAKVPKSFILLLSLLGLGLSIAIAVLSTLGEGKGLFLENWLTVAAWALLFFQSICIASSHSSVTAYGLGLYSALSCVVLAAALAFQDNRVAQDLLRHDKAAFVLRVVEIATVVSLAFASLSMPRRPDVFHNDQLVDRYYTSSAWARFNWSWPSNVLRHAAKKNSLDLADLPRPDHFTRAKETTADWESRGFKGPLWISIILAHKWMFAAQWFATLVTSFLNFAPQWCVLQLLRILERRTNREPLGYDAWIWVIWIAVAIIAQSWVESQVFWMSWAELCVPIRAQLSSLIFKKSMRRKDMKGAGKKKTQDANATEPTIAAPSGESTAIDKPDTEETEEEQLKKSKQSTVNLIGVDAKRVSDFASFNFYFPGSLFKLIVSLVFLLDLLGWQALIAGFSTMLAITPVNAYFSKRYSAAQDKLMKVRDKKMEVVSEALQVRERELNSVWNAFINDVFLIGCWLTSPIMLAAVALAVYAAIHGSLIPSVAFVSLGVFRALEVTLSVIPELITDLLDAWVSVKRIDDYLQGAEIVKSTNESEEITFDNATIAWPADEKDNDDPDRFILSNINVTFPKGELSVISGKTGSGKSLMLSAILGEIDVLSGSISRPRAPMLSERHDTKANPGNWILPGAIAVVAQIPWIENATIKENILFGLPFDEHRYLTTLEVCALKKDIEMFSDGEETEIGANGINLSGGQKWRITLARAMYSRAELLVLDDIFSAVDAHVGRHIFEKCLNGELGVGRTRILVTHHVALCEPKTKYLVELGDGGVLHAGLKSELEEDGTLQQIRSHEQTEAEIQADGDATMVNSEETSQADEENGEPLAKVPSKKAARKFVEEEGREKGAIKKHVYATYLSDSGGWFFWTNVVLFFVFVQALTVGRSWWLKVWTSVYENEKTQMHSTKEAYAYSMDLQQTSFRQTSFRQTSLHRLMQPVIESHRGIAFYLGIYVLLAVASALLGTIRYYYIFCGSIRASRKLFARLNFVILRSPLRWLDTVPVGRVLNRFTADFHSVDTHLAYSLAFGFAAFLNLLGVIVAGLFVSPVILALAALLLFISAFYAVQYLHGARPVKRLESTTKSPVFEQFGSALSGVATIRGFDKAPVYVDRMYKKLDDWTVATWHLWLFNRWMGWRMAVVGSFFASFVAMLILLTPDMDSALAGFALAFALDFSSMVMWTIRHYANIELEMNAAERVVEYTELPTEDLGGEDAPAAWPTEGRVEINDLVVGYADDLPPVLKGLSFSVNRNERVGVVGRTGAGKSSLTLALFRFIEARSGSIFIDGVDISKIKLHDLRSRLAIIPQDPVLFSGTVRSNLDPFDDHTDAELLDSLHRVHLLSENETSPGTPVAASDSAGDGQRSNTNIFRDLASTISEGGLNLSQGQRQLLCLARAIVSRPKVMVLDEATSAVDMSTDALIQRSIREEFDDSTLVVIAHRLSTIADFDRILVLSDGKVAEFGTPKELWEADEGKGIFRGMCEESGEKDHLRAICLGENKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5J2</accession>
    <name>A0ABR1V5J2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662068.1">
        <property type="nucleotide sequence ID" value="XM_066816376.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049436"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="300" mass="32656" checksum="A7741C0209064FD0" modified="2025-10-08" version="1">MEYLKALQSAAQGVPAVVVRLYSGSLTMFGYLGAAIYWATVPLRYPAYYVYAVISRVLSVLLSPLWFSWSVVSRATLMVVNFLSGLKFTCAIIVGLVAAFAIHFISRFVAMLLSVHPSQQLRQQQKVLEEEQQQQQPFQPQPQQRRFPIQNGFGGGPQQPPPPEYDDDLDGGFFNDDDSIKRDDYCYVEGNDGDGESLAGSSTGAGGRFADLGGTTTTTTSSESAFNIPTTASSSRRRGGGVQNPSTSPVLSFGGNDMYRRDWRSLSSNMKSSAGSRRGGSIRSLLAQTIHEESSESDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5L9</accession>
    <name>A0ABR1V5L9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663247.1">
        <property type="nucleotide sequence ID" value="XM_066817555.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050615"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00048">
        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42030">
        <property type="entry name" value="DRBM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42030:SF1">
        <property type="entry name" value="DRBM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11878" checksum="DE8B9DC043757786" modified="2025-10-08" version="1">MPSSSSSSSHHHHHHHHSHQTTSSPWQQKLEEVCRECDSPAPDYQLVSDRRGGRTAWSSIVVVFNTTIQARYWYDGKNLNNAREDAAEAALNWLHQNCGHTQAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V678</accession>
    <name>A0ABR1V678_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662488.1">
        <property type="nucleotide sequence ID" value="XM_066816796.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049856"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="153" mass="16410" checksum="A5C346BFA340B40B" modified="2025-10-08" version="1">MASLIKFALVAEAIFNVLGALIFIVYPHACLSHAVLSSTPVTGCAALLCQVFGAMVLSLAVPLLLCVPDSNAVYEKRRIVYKTMAAGEIAFIILFLRASQDYEKTGFAPEFLTKSIMAFAPALAWHSYAVFVNPAIMRTAGAAAPRADVKKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6H5</accession>
    <name>A0ABR1V6H5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663558.1">
        <property type="nucleotide sequence ID" value="XM_066817866.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050926"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="123" mass="12415" checksum="1C0C8636B2C8CB52" modified="2025-10-08" version="1">MVVLTTGDGVTVTVDGVAVTVDPDTRIDTELTMLMAVDVSVMVAAEGQLVGSELSVAEAQQLPVLVTYTVAVVAAQVVPPARNALAELGGALVCCVQYGQGAFVLAGAWDGCHGRSSQGAGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6Q2</accession>
    <name>A0ABR1V6Q2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662668.1">
        <property type="nucleotide sequence ID" value="XM_066816976.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050036"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF13">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="41"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="261" mass="28965" checksum="06AABC6152E456CB" modified="2025-10-08" version="1">MGPTIVICSGAWPLELLFQPLIQAFKAIGQDAICKVPQSYPAVDPKNPPERNYDSVFLRTQVLDPLLEEGEDVVVFMHSYGGVYGPESLDGTSKKERMAKGLQGGVVAVIFAAAYIASEGVSAIDTMGLDPDNLPDYLEHDRSTDLVGFKKAAAKAMLFHDLPDEEADRLADLLPKQPFTCFSTPVRWDPYRDTNFQGLLGYIHTETDRILPLEKQKHYVGSAGIETTYMMKDMSHSPHHEQPDLLARVVVSVMRTIREGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6X2</accession>
    <name>A0ABR1V6X2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013693</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663699.1">
        <property type="nucleotide sequence ID" value="XM_066818007.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051067"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF6">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="57"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="365"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="546" mass="60294" checksum="1B74E3AE1A4C80A2" modified="2025-10-08" version="1">MADTEIREKGPPAESINDKHSAGASPGGGDSDVAEGVAVNVTAGSQALHRKLQAKEVQLFAIGGAIGTSLYVQMGSALPKGGPAGLFTGFIIWGGIMWAVNECFAEMVSYMPIPSPFIRFAGEWVDGALGFAMAWNFFLNMAFLVPFEIVAMNIMITFWTDKVPVEAIIAAMIVLYAVLNVISVRYFGISEFYLSIFKVFLMLGLFAFTFVTMLGGNPIHDRYGLRYWKEPGAFVEHLSPGGTGKFLGVLSCVYQASFSITGPEYISMVAAETENPRKILPPAFRSFVWRILVFFLGSALCMGIVIPYNDETLLGILGGKVTGSGTGAASLAAPRQRPDHDLHLQRRQRHPLLRNPDPARHGAGRIRPRFFSWCTKGGIPLFSLLLALSFSLLAFLQVGSSSAKVLTYLVDLVTCCQLINYGCTALTYRHFYSAMERQGISRGRFQPYTSYLAMGGTLFMILAAGYDLFMDGGWDVMWFFLDYGMIGFFIVAFFFWKFAFKSTYVRPGTADLGIGGMREEIDSYEAMYVPRPESKMSRVWNIWIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7S9</accession>
    <name>A0ABR1V7S9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663998.1">
        <property type="nucleotide sequence ID" value="XM_066818306.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051366"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="141" mass="15792" checksum="7D3D3B03CA9FF042" modified="2025-10-08" version="1">MDNQFPKQKPTSVVLDRWRCLDIVVTRLGGPSGEYEVVWRKMIVGVPVIERDCTGYIASSLEYIATSRSKMGGDLLRRRETSGSPGRRPDHPPSCQGREMITLGLRLVLLVVDDDDDQWAADRGAIVGHDDQTSSRDRHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V810</accession>
    <name>A0ABR1V810_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664084.1">
        <property type="nucleotide sequence ID" value="XM_066818392.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051452"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542:SF1">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="56433" checksum="44DFA28D12715F3D" modified="2025-10-08" version="1">MAEPGTILTAVELCFKLGVRIAEACETWKNADTEIRERAIRLNLYWAQTRTQIEFIQKVVKTIDKDLLETIDDVLGVLATKLSLASAKLDKLLESPGSAAAPASSTWKVKRGRYTLTKNAFDAIMDDLEQWQKRFDPCWFLMMRIASPVIDQELGALNENDADKGPKDQRPRTSSIATSATAVSLADGLRDALREPPQRTTSVFLPLDPSLDFSPIAFSSARLALRHRKDKPSKQFIVDRFGVLPQSNQLAVKKDARDLARKLANADPITFGLLKAKGVMTVQGHDSKHVEQFNFIYNVPDGLTSRTSLRQALMQDHDCLHLSQQIRMARDLATSVGFVHNFNFVHKNIHPESILLFENVESTSTSTFLVGFECFRSADAGTLKKGDAEWHKNLYRHPTRQESTQKRRISCNMTYTVLACARNPEPGPLLKEVQEESAVDPSNDDEGGGSMLPAEMREAYRIKDSLLSIAKTRLSRRMGPRYSAVVATCLTCLDANNEDFGDESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V940</accession>
    <name>A0ABR1V940_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663569.1">
        <property type="nucleotide sequence ID" value="XM_066817877.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050937"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38794">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38794:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="3">
        <location>
            <begin position="47"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="426" mass="46359" checksum="500A50DBF7367F1D" modified="2025-10-08" version="1">MEQPLDLNEYEPLYPVSDDNHAAYVVVPSLIFFAYAVLAVIAKNVLRFKWTTVKLHDIVLIVSTLLLVAQTACVVLSCNSGLGEPSGQAFQRANTAIQPGRAEDLLFTYSFGTHVWWIPPTTHHYLTFAADLLSLFAQTCAKISVSLLISVISNQAYPWSHKQTVHGINQNHLFDANRFLFSLIILCSVVGVFGLSLQCGLGGVLAEPWSAASLGHCSWGGEVWMFNAVAGVITDLGLCVLPIAMMWKVQTRSTVKATVTILFGSRILVPLIALPSIVQGPQVTNGSNGADVTWLAVNPTVWHQVSINLSVLTACIPSLKSFIDSLTGYTSGLRIMLPYEYPNVSSGSHNHGVRSAIAAVYRGSRPGVNTTLVSSNQGDQHRKRGDGCDTNPRTESTQDLTEGVIHRSDHVSVTFERAPSHYPKYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAT8</accession>
    <name>A0ABR1VAT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein rhb1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663897.1">
        <property type="nucleotide sequence ID" value="XM_066818205.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051265"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04137">
        <property type="entry name" value="RheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="187" mass="20806" checksum="3C9C7920673D0F36" modified="2025-10-08" version="1">MPVPSKQRKVAIVGSRSVGKSSLAVQFVDGHFVESYYPTIENTFSKLIRLKGQDYATEIVDTAGQDEYSILNSKHFIGIHGYMLVYSVSSKASFEMVTVIRDKILNHLGTDWVPIVIVGNKSDLRPEQRQVSNEDGQKLAEKYNCAFTEASARYNECVAKAFEILIAQIEKGQNPNEPPDGGKCQVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH00</accession>
    <name>A0ABR1VH00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664324.1">
        <property type="nucleotide sequence ID" value="XM_066815034.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048094"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="172" mass="17997" checksum="35FDB77CAEAF6038" modified="2025-10-08" version="1">MSATRNTESMAAKHEEFSSRATSPASWSATTRTPSSTPRRCPPAARPREATHQPRPAEGENLYQSNEGGGAAKAAATLTGATSQDVYQGYGKPMQGQENVELRHDGQHTSKHVGSGLAGVGAADAGYDSVRAKGADLPEGVTKGSRGKATDAYPTAEERLPESAETVASERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VID2</accession>
    <name>A0ABR1VID2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7728 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664766.1">
        <property type="nucleotide sequence ID" value="XM_066815476.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048536"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056145">
        <property type="entry name" value="DUF7728"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40622">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40622:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24854">
        <property type="entry name" value="DUF7728"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046264810" description="DUF7728 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7728" evidence="3">
        <location>
            <begin position="50"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="374" mass="40996" checksum="712C850822827B9A" modified="2025-10-08" version="1">MHLSSLLTAAGLAVSSTNAFLLPLSESSDNDAITTLPVPINAERVPQISEKRTLKLDCPGCSALAPGRHHAMSKLAAADIPSYLELDFSVDHAANSDRLLLNGFELYPNSDPMASTLSAKLQNDAMPHHRMMRPGHMRHNKNEFPLGFGLRTAAVAKNEEDNMELYQLDLQIIEVGNVFIDGLPNVQVKVIKTPEGGLMIGNVDVTASESGQKGKPETCTSWVCRMKAAAMQQLARLRTFKSCHGKPKAMGKLEGMHRHPGPHHLNDAPQPPRPMEPAHEEHCLAHPAAHCHRNRCCLGMMVGTAIVCLWRTFVRPAGTRRHHRRRGHSVHKAAHNETAASDEKAGLMSHQEEVDTPPSYVEEGLVEDKKPNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ69</accession>
    <name>A0ABR1VJ69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011477</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665082.1">
        <property type="nucleotide sequence ID" value="XM_066815792.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048852"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026505">
        <property type="entry name" value="Solute_c_fam_35_mem_F3/F4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19346">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19346:SF4">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="527"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="235"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8071274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="582" mass="64686" checksum="87D7A753A879049D" modified="2025-10-08" version="1">MSSNNIRLSRIPPASLHPTARYSHLSDSANQPEPSPLSAASYASSDISDWIGSGTDTVGGRTPVIDRRLSFVPEDEYSTDGEDQARDRNHLTHGNTRANSSRYHRNRKSTDSDIISNSDDDGGDEDDMDRPSYLRQNNGRSADPLLFKADDDNDDMERGRTPYDSLRSPSPKATPSRPRLSRRSTMRSRSPDTQAVMAARKKYIFAAVFLVISLVSFTIQTELGAYVQNEKGWNKAYCMLYLTHGSWAMLWPVQLLILRVQKWNTPWPTFWRRHVAILRSTAQQVRHQDLEPSKQETSTSPWPYLIRTTAFITTALTIAGLSWYLAVNMTSPSDLTAIYNCSAFFAYAFSVPLLKEKLRLDKSVAVLIAIVGVLIVAYGDSKPEDASKGPDTSSGTRFLGNMIIGAGSILYGLYEVLYKRWACPPEGVAPNRGMIFANAFGSCIGTFTLTVLWVPLPLLHWLGWETFELPTGETAVWLFLSVVMNATFAGSFLVLISLTSPVLSSVAALLTIFIVAIADWFRTGERMSLAAILGGCLIIVAFLMLSWSTWREMTEDAERKAHDASVEAEWDSDDESDKDGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ95</accession>
    <name>A0ABR1VJ95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011514</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665119.1">
        <property type="nucleotide sequence ID" value="XM_066815829.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048889"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7025" evidence="2">
        <location>
            <begin position="368"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase lid" evidence="3">
        <location>
            <begin position="841"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8071311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="899" mass="100568" checksum="AC5FFEF9F308F2BF" modified="2025-10-08" version="1">MQGDQAPTRASQLPLFRHLRSLHPRGLAGGCNGEISSELGSAIGLQCNAQHSKGVPEDATKAHSIDAAEPGDATGKEASVASADTPKVDEVAPQPANSIDPKQTLESDAPLWCPVTLRAHSILLDFRMITCPACHQYLYLKKAKKATDVATEPEDKSESSDNVEAEKVLVTNTVDFRDIEDDCVERAPWPGTFDLLEARKDMVDDNLAFEVVTVLETSITGEPGQTRVRSRPQGPARGTARAPFRSSTTPASEILSDSKLEIAVRQTTIIIHSRALLRLIKSVVSYYPSVSLDGKTVDLAEPFALIAHHLSQLENFVADSVDPSGLPEPKTRAAEKKDLANRQLGSLLRFVKQPKYTSPIEEEMARNGRGYCTFRMLWYLFRPGGTVYLSRDGKLDALVISDVTIDVKILRPEAKSLKPYDISLWYLDFDGRHVGRSEESVSIPAFEGERLITSLKLFPVEYRDNSDGGETKRELEELGKRWFGYLLGAQSHYKGEFIGPLGRQFDGRVFVDNAAYIEEESATNPPRQPAKPRGGPMPGPPRPNMPGPPPMATDSEADKSSHREIPVVGDVDDLGEGLSVCSCDDCLGKRVHPPPGFQWAAYDLIDPRVTKTLELPGSSHGKDHRYLLCSRRLFGFVFKSRRWEVLDVKFCSPARIQPEALKSLVMPEERKTIIKALVEQYNTARSKDGSPQRKQWGADYIESKGEGQIFLLHGGPGWESLCEFSSHSYATAECIAEFTGRPLLSLTVGDIGTFEEKVEERLSYWFNLAEKWGAVMLIDEADVYLERRTVSDLRRNGIVSVFLRCMEYYRGILFLTTNRVGQFDDAFVSRIHLIIHYSPLGEPERRKIWTQFFEKLEDERDDISITSRARKYVLHDPEINDVKWNGREIRNGKKLTLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKH1</accession>
    <name>A0ABR1VKH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664191.1">
        <property type="nucleotide sequence ID" value="XM_066814901.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047961"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="410" mass="45226" checksum="F88387F0182DF50D" modified="2025-10-08" version="1">MHYIRLLRPVSVETTNRREEVLSVLLTITTDLGDSFFGPDEPSPSAVLAYPADQKSPLQWRAGMRVLKAQLRLREPLPREKTTVCIFARGSDRSKTPSVRPYWRHGYEDEQAELVVSVSVDMANRTCAPVSLRTLPLPRQADDGDGASNEDEHSLELGEDIGESIARHIWDAGLVTASFLGDSCRSAAVMADILPVRRDRINILELGCGVGILGTTVAGIIQDAAAAQGQSLLEAQVLLTDVDEAEERARANIARAEEVLEWRQTHVSEEGNGEEDESEEKPRPVRLEYENLDWDDGRQGAFGPLVVARAWDFVVLSDCTYNVDSLPALVGTLSALHKHSHSFQDDDVAADTRVILATKPRHASEEALFGLLGEQGWAHRVVKRVPLPRVGAEDEGVEVYVLERKESGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKM7</accession>
    <name>A0ABR1VKM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011640</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665245.1">
        <property type="nucleotide sequence ID" value="XM_066815955.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049015"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="12"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8071437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="446" mass="46551" checksum="3A7E85341F5ADBA8" modified="2025-10-08" version="1" fragment="single">MEARRLPYLIFLIAVSTLGSLQFGIHLAELNAPEDVITCRKKSISTRALPDCIPMDNAAFAAVQSVFTIGGLVGSLGAGPVSSAKGRLFAMRLTSAFFVLGSAIETLASAVPVIAVGRLLAGVGAGAATVIVPLYISEVAPPKERGFFGVMTQISINVGILLTQTLGYFFSYGSAWRWVLGTGVIVGAAHASGLLVVPESPAWMAANENVTKAKKILQRIRGSGYDINEETISWGPDVAVPEEEAALLDGDNGVLAPPPTGRKTAGESGSHKSFLEVIRDPLTRPAIIAVVGIMLSQQLCGINSIIMYSVSLLADLLPISSALLTILISVINLVTTVACSPLPDKLGRKTCLLLSIIGQGTSALCLALSIMFEIKILSAVLVLCFVASFAVGLGPVPFMMASEMVGQDAVGAAQSWALGANWVATFLVAQFFPLINKALNSALGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VL23</accession>
    <name>A0ABR1VL23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664447.1">
        <property type="nucleotide sequence ID" value="XM_066815157.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048217"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="888" mass="100062" checksum="67AEAB021D524A29" modified="2025-10-08" version="1">MDPLSLAASVVGLASFGLQVSGGISTYLDALKCREGELEAIRRQNAALRNTLAAIEATSTTIQHLSPRAAAAAAQTISSCADDLSALELFVAHLSESDLSTWRLRLKGKARKLHYVFDRPKINQLHTRIAQSKAALQLAVGQLELTINRVNMDMLSSVDSTLHDNSTEVFLVRSELGHAHQTIQSSFELQQGFQERFDGIESSLQTLLAACERAPCMTGDGKSLTRAAALLAAKPAALKEVCNFNQSGCICRRRVQTQLEYSNFGSYYQVYTEDTKEGHSPYCPLYRITATKRRRKYGLRLTGLTHVLKAAVEISFSVSSGAGGRSISPQFTYYPTVDTRMDPAFRVIFCLREVIRQNRCHPSFYPALERKAMENIIRLFAEGKSSPLAVDSKNRSLMHHAFGASGSGSLIMAVKTKNREQVLYLLTKHPDSIKEQNHFGHNALLVAAYENSLPLFPELLDAAIAADVFNERDNIAISVLQVAVEHTSFHCTNGDDGVECTQCSCSDSVSIVMDKCAELIAFDYQFYLCRRLEAASQRCRRLWLRHLKGQREGLKEFALRHRWALRAVQHVLESTEVLDLHATQVCKLLQQQDIQVPAHLVPHEILQTSENHPSLYCMIDSVDMAEQLFELGFREIDYDQHYGRQPLRTLYIHDPHLSLWFLDHGADPQRLIKLEGKVNGEDRWITTGHEVMLRVGEWMDRYGDSFGISGSHPYFEALSRITATICSAPLTDGCRCVCSPGGCTPFTCYLKGRLRPSATDSLNHYKILQNLTAEEGKSTCYTWDPDRTMDDDEVMEIQDEEHDLIETFKELPAILEEIESERMTEEERREAEMIGVAWVNNEEETRVYYPEAPDPAIWTEDNWEYLLESELRCPGRLNLESTISIPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLA5</accession>
    <name>A0ABR1VLA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HET-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664522.1">
        <property type="nucleotide sequence ID" value="XM_066815232.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048292"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF12">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="222"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="813" mass="92816" checksum="BC107DEFCCB8A27C" modified="2025-10-08" version="1">MPVQPPHTPDSTISPSSASAIFEVPTGINMNSANQSITAADADDVTTDIATSSITACDICLKILQIFRTPFDEKCEIELGKVRDILAHECGHADWIRDIQYMYGTGPRYEGRSLALHKWEHHRDAFFGLSFMTQNTSAWSTTKSFELVFRPDIPSHPGTARILDRHWIDFDLVKDWKSRCFRDHGDQCDKSIIGSARPVYPQWLINVVDGCVVPCPKDGPRFVTLSYTWGRTRHFRTTRSNLDDVQNAGALRDGHVASQIPQTIRDAIELTNALGEDWLWVDSLCIVQDDAVAFDHQLKNMHHIYATSILTIIAKDGQDAEHGLRGLQGLSSPRSTTQLVVPLAAGERVVMMKTDFEYPKASMFDYDERMWTFQEQVFAKRRLTFTNGRVEWLCSCAEWHEHQLYHAEADRRSARGAPDLYVSRGLLMRTPSLNGLCDVVRRFNQKALGFDEDVFNAFSGLHTHLSTIFPSGLVFGHPELFFDISLCWYSVDSLRRRQVSQYYTGDPVQNRLPSWSWMGWDGETIFPADLEYKQVPSMDLGFTQAVTKWYALPEPGSTTKRLIDSTWHEHRAATPQRTPKGWKRIEFNPPSEWGGHGDSLELRATPFSMPRELPRYAYVHVSQDGHRGDYQWYPIPVKESDSTSDGDGESDSHSNFQYLQSVTTRAYLYRGPNKYEFPGNYIHLLYDLNGNTVGGLRGIRSKDESRALENGARLELIAMITPALTPPEADAFLTEEEEEERMGQQAAENEREANRRTPWMERWGEDKKTKQDCYHVLWIEWEQGVAYRKGCGFVLEDKWEELAELDEVEVTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VMQ7</accession>
    <name>A0ABR1VMQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ABC transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_011698</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665303.1">
        <property type="nucleotide sequence ID" value="XM_066816013.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049073"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="716"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="760"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="834"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="50"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="383"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="720"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1046"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="668"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8071495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1267" mass="138052" checksum="904B97BB967E8592" modified="2025-10-08" version="1">MSRPSVGESSIVTTDNNTRTPPPTDRQPCLADYLRIFRYATRWDVCVYTVGALSSLAAGVTLPLMNVLFGQLASQFTQHASLSAPSSSSISDFEELLSKQSLYIMALFLGRWALNSINKFCFRMTGLRLSAAVRLHYLQSLLHHNIHALDTLPAGAPAAAITASANTLQIGVSERLGTLLQFTGTVVAALVIAFIWSWELTLVTSSLVLYSCVIMVVAMPVLLKSHAAVSRAENRATAVASEALGAIRLVMAAGAQERVLRNYERWVREAKRQTRKTAPVFGIYFGLIYLGLFGSYGLAFWYGTKRFILEGSGSGGVGTVIVVLMSVMMVLTSVERISTPLTAISKAMVVACEFFTIIDAPAPKCGGLRMDLDGDGGDTSKDLVFENVMFAYPSRPGSKVLDGLNLRIRAGLNTAIVGPSGSGKSTIVALLERWYSLSDQPSVPKDRVELSGSVTFSGHNIEEFDVQWWRNQIGLVQQESFLFNDSIFNNVARGLIGTQWASAPEPQRRDLVFSACKEVNAHEFISRLPEGYDSRIGDGGIKLSGGQRQRIAIARSIVKKPRIIILDEATSAIDVHGERIVQAALDRISRNCTTITIAHRLSTIKKADRIIVLRDGRAVEEGTHEELMHVSSGHYSRLVHAQALTNLSVRDEHFSDGVNASPSLLAAQEKGMQEHEESNPQFTLDTDLEGKKETTPTPASFRSFATLIHQQQIHPLFFTGILLSAMCIAAGTPIQAWLFAKVVGVFTIQNPAELRTSSNFWALMWLALAGGVGLSYFAAAWIGVAAQSRVGATCRASYLRGMLYQKLPFFDADANAHGALTGRIASDAKQMEELLGLNLVIFLSGVFTVVGCLVISLVFGWKLALVGTFVTMPVMLASGLWKLRQEVKFDQMNSAVFMESAQFATEAVGAMRTVAAFNMEESIIDRYRVLLDDHVKVALRKAQLNSAAFGFTDSASLGCQALIFWYGGRLLLRGEYTLEAFFVCFMAIIQGAENAGIALGIAPNAAQAFTAANRILNVQTSAEADRAGTSEHQSDSIPDMEGGIQVEFRDVHFRYPTRDVPIFQGTSLTIQKGQYAAVVGPSGCGKTTIISLLERFYDLERDSGAILCNGANINEFNRYSYRQNLSLVAQESTMFQGTIRDNILLGAASSPEHTISQAKIEEVCRDASIHDFIVSLPDGYDTDVGQKGVSLSGGQKQRIALARALIRDPKILLLDEATSALDSESERAVHGALERARRGRTMVVVAHRLSTIQNADVIFVLDKGCRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VN70</accession>
    <name>A0ABR1VN70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665167.1">
        <property type="nucleotide sequence ID" value="XM_066815877.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048937"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="51808" checksum="029A9966F5D82AB8" modified="2025-10-08" version="1">MPSSETPSTFTTWVANFLQALSFTKRPVNQPVVGTELVKAEIPKRVITAHYIRDFAKHLEKAGQEGRPLLHSDCIVCRRTLSISSSVGDLVKEECELAGDETAAKSKLEFYEKHDIEHTVVLRCGHLIGAECLREAVEFYASGHPSAFRPNICFHCRAKTACDGCDDNLLADGSFDPFHKWTTWPLGESDTMMYQPWAGFLRVGLTAAEKDPKAKRYCQRCTYYQILRKFSEIALTFPACDKFASAEECQQWLRQRLHEASRVICPLTDDVRNRRIAAWNDMFLAKGRDYFVETCMGAQGRGAKLHGTVFCQCTGDIETLSPKRLRGFKRKQKRRIRDTKAVFKLAERWTERFMAIANTMPLAWYRGSEEEGGMGDAAAAAFDSSRAKPRIGTCPSTGTSASSRSWEGTRSLTRCRGSITQSSQVRSWLSWWRTLTSGSTPVRLMPITLSLLENLNHGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT23</accession>
    <name>A0ABR1VT23_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665349.1">
        <property type="nucleotide sequence ID" value="XM_066813387.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046447"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="280" mass="31052" checksum="B88C5AAAEA3ECE31" modified="2025-10-08" version="1">MSDNAAPQDSPSAIKPKTPFKKLVDSLVLRRNYKLNSKVAKQPPSEEARPEDYLTIHNLVAALRTVDFCQSSTGSGVRVKQLERMMSHWEESEKKFPWAASRMPGTRSSPGMSAAVPGSWSEPTGPTRKCGIAQASSACSGAFTLGTIWTSNHPEFSDVPPPDPSGGILLSHWTKTCFKLMVEVKEDEKGVPGCPTGAVWVVNNSGYHRKDIEKGANTQLEGVLMARVADSFKDLVDCGRRSRWPKFEKAEADYLDYYPCYQRNIRGPIVWKHAPDDECY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTU6</accession>
    <name>A0ABR1VTU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665626.1">
        <property type="nucleotide sequence ID" value="XM_066813664.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046724"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="72" mass="8532" checksum="8A4AADE60AA44D17" modified="2025-10-08" version="1">MLDSRSMECLYEHFSAQQQQPAHHPEQQRLASFEEKNIKPSNISRGETERPAATVARSHRSLWFFWRADMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVW9</accession>
    <name>A0ABR1VVW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_010054</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666331.1">
        <property type="nucleotide sequence ID" value="XM_066814369.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047429"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF23">
        <property type="entry name" value="FERRIC-CHELATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="295"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="497"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="502"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="527"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8075391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="617" mass="68084" checksum="1E11123EA18116DF" modified="2025-10-08" version="1">MPLPWLDQPIMLESSRMDMCELTPEQCTWSRSRFRNWYIADLVYGLGTLYFFIGVIAACMISFWASRLVVGSSRKRSSWRKLLGAFRYLAYRRYKMAGCLTPSVGVVLLLASGALFFLAMTLGPGPYYWPDIMYGSSPPIATRAGWMALACLPFILILSTKANMIATLTGVSHEKLIIFHNWTGWAMFVLSLVHTFPFIVVHIQQGDMVMQWNMSIFYWSGVVALVAQAYLQFMSLSFIRNRFYEFFKATHMLAALIFVLFLFFHCDYTLTSWHYFIAAGVLYTLSFLYSQIRTYSEFGFGLRATFDMVSDTTMRITVPARTTWQPTQHMFLRFVALQAHALTSHPFTICSVPAATSPLTDEKSNLVFYVQARKGVTGRLAKMAAARGGCTVPVLIDGPYGGIKGKPLSSYDDNLIVACGAGAPFSLGLVMDALLLRRAFAAKADAGVVTLPNVEVLIATRDPQFVQWYCEALTDFMESNGLPIDLQGIRISLFQTGGSGNSRSPTAMSTTSTTPDNDAEAREKSAVSDTKVSSSSSHSGNSSSKSLQLEIRSGRPDIGAMVRQATRRPNVSLALVACGPGGVVEEVQAAAAEAQLRILGSGNEGAREVYLHTEHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVX7</accession>
    <name>A0ABR1VVX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010064</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666341.1">
        <property type="nucleotide sequence ID" value="XM_066814379.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047439"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="129" mass="14867" checksum="D55CAA2ECE30FEFC" modified="2025-10-08" version="1">MASQKTSAQPRKSADLKYGQQRVYMKSRRGMELTEEKLENTAYTTLNEAKKKKILDAIKKELKDNIEEDQKIMPAGDLLDYEKLVNGVIRKVFGENLRLFKDNRGARASRDAQTREDTPVVDELLDYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW01</accession>
    <name>A0ABR1VW01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamine synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666347.1">
        <property type="nucleotide sequence ID" value="XM_066814385.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047445"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF12">
        <property type="entry name" value="TYPE-1 GLUTAMINE SYNTHETASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="5">
        <location>
            <begin position="122"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8075407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="479" mass="53458" checksum="8E728D6DDDE930BD" modified="2025-10-08" version="1">MSAPQEEVTLESLSELLKDDNKVKLAGIDVDGQLRGKIVSKKKFLSVAKSGLGFCSVIFGWDMHDLLYIEELKVSNKENGYHDILAEVDLKSFRRIPWENNVPFFLLNFLDPDTQEPICADPRGLLKVQLAKLKAKGLDGMAGGELEFFQFKLPPNETSPAAFLQNNPAHALSSLTEGMFGYSITRPVHNQDYYYDIYDTCAKFNCDIEGWHTESGPGVFEAALEFGQVSEMADRVSMFKYVVKSVATKYNIAPCFMAKPRSGLPGNSGHCHFSIVDKDGKNLFYRETKDENAPYPDAAYLSDMGRQFLAGLIEGLPYVMPMLAPTINSYKRLVENFWAPVTVSWGLEHRAASIRLISPPTAKPGATRFELRVPGADANPHFVMAALMGLGWRGVEKKLELTTPPLGKGEDVGGGSDQGIRLAKSLKEATDMFMSKDSIAREVFGDDFVEHFGGTRRHEIRVWDEAVTEWEIKRYIETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7C4</accession>
    <name>A0ABR1W7C4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heterokaryon incompatibility protein (HET) domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666857.1">
        <property type="nucleotide sequence ID" value="XM_066811515.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044575"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="162" mass="18845" checksum="7A5BC089CC8FD97E" modified="2025-10-08" version="1">MNRSNSPNISGHYSRHLRFETRMGSLSLGRIIPWNERRLNNCLNAELIELENENWAGAIRLLPSQLEELEQARSGRKVDLIEVAAGGVQEKDWPKVCEYTHKRYSFPECNYEGSPKGTEVYEFYFVLWVEWQDGIAYRKALGRVEKQAWLRVAQERISVTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7H2</accession>
    <name>A0ABR1W7H2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666837.1">
        <property type="nucleotide sequence ID" value="XM_066811495.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044555"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142">
        <property type="entry name" value="METALLO-HYDROLASE/OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142:SF2">
        <property type="entry name" value="METALLO-HYDROLASE_OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="352" mass="38959" checksum="70BCEA9A4F96B081" modified="2025-10-08" version="1">MATNNRSALLSAHMEKSKQSELRPILTSLNGDNSWLMAFPVPASKSRTDPKPQKAYYHIVWDPWFATSGAAVTFASWLASVSQTAQSTVNSGDDVERIAREIESKAAEAGLVKGVGGEENLMVDAIIVSFYYTDHMHEASLRKFDRRIPVIAAPEAAAIMEGWDYFQTIVTMKDMGDEGSNWQALHPSGPLPAWLTPFRLKGEHELNFATVLVWSHRGVNGGNVAGAAPTTTHEALWVAPHGIRMDQPALQAFLRDTTKTVDVLAMLHPLKESFTWGWQNVYGVMGGLAIDRALKDKGPKYWVPAADAVLGYWGLIMLRVWDIRRTLDWGLAEEEGLAGERGRWWSRGSPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W859</accession>
    <name>A0ABR1W859_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667142.1">
        <property type="nucleotide sequence ID" value="XM_066811800.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044860"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019240">
        <property type="entry name" value="DUF2196"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03833">
        <property type="entry name" value="YwbE family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40069">
        <property type="entry name" value="YWBE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40069:SF1">
        <property type="entry name" value="YWBE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09962">
        <property type="entry name" value="DUF2196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="20398" checksum="FC36871D930DFE27" modified="2025-10-08" version="1">MASRVPTTSQVIPGASVSIVLKADQRTGREVQGIVRDVLTRGDHHRGIKVRLADGRIGRVQRMAPKPADGSAAPDSTTGAAVSLGGPTPAQSAPQIRNEGRQRPQYQDVRFDGHFEPPSEQIDLAAYIKPAKQKKKGRKAAKDEPPATDAAPGGGGEGSNANPATDVVSATATCPVCGAFEGDEAAVAHHVATHFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W867</accession>
    <name>A0ABR1W867_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667150.1">
        <property type="nucleotide sequence ID" value="XM_066811808.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044868"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="479"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="535" mass="59510" checksum="D477573B57F062C0" modified="2025-10-08" version="1">MEEHIVPVRRVNCILEALQSTEAALEAVLLSLSKVATKILCAVEQNPVEIRSRFLQPREVSAILIVRRIIVELFCDEVVEVGRCVNLTICVPFEVDAFIEHVLVNPVSHESVDRFESLVFLGVNVVAAPDLRPLLLAPELRCRCAFRSASTRLCLDLEFRNLEFRGFQVGFSGVALGFRLFERVFGILERGCLGGQFCLECGFRCSLLCKRVGAFADLNLIVCQPPLQFCDPDALSSIMGVCGIVVFLLHVGLRFCHLLPEKLLIRVFCFDLRRQIVDSLRQIRQLGITQLGITSRGAAVERGNQLLEVSEFGFQLLLGVTPVLGFGLGLQHQGRANAQVISDSLWDSHLGQGILAENVLNALFSLSQMGSLALYTRVSSSWAAGPAATKPGWCLIVIDDHVFWDRLFRRECDFLFHRRRIKASKGRRYVVFVGWTLGHLQLFHIFHLRLECVKLVLLVVAHRTLVAAVSEKVGLTDRLLVLLVVLRFIVVFSVGAVIILNGGIVSIFDRAAFCIRVTAIVVDLEAFVVNFGAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8P2</accession>
    <name>A0ABR1W8P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="3">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007676</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667333.1">
        <property type="nucleotide sequence ID" value="XM_066811991.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045051"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF38">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="388" mass="42360" checksum="A1401961FB891EDE" modified="2025-10-08" version="1">MFVKSVHGAAVLAGSFVAPRDLNINDVSSIRSVASTLAYGTMSYYTGNVTNTPETLAVFPAPVYWWESGACWGSMLDYQHYTGDTSYKDVITQALLSQVGPNFDYMVPRHQGDEGNDDQAFWSFTVLEAAERNLPQPDDSIPSWLTMGRTSGTRWWLVGTQQPVVANSVSNGGLFQLSARLARATGNQTYQDWAAKIWDWSESVGFIDKDFNVLDGADSRDDCQKVNPVSFSYSQGIYLYGAAVLYNHTLGDATWGDRTNKLLKATASYFGPFDNATGVMFEHACETVGRCNTDMLSFKAYLSRFMWATTQMMPSTLSQVQAVLNTSAAAAGRACSGGANGTLCGERWYVDGFDGNTGLGQQMSALEVIQGLLVQEATPPSRRARSSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8V6</accession>
    <name>A0ABR1W8V6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667381.1">
        <property type="nucleotide sequence ID" value="XM_066812039.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045099"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="617" mass="67782" checksum="00101631848D09A6" modified="2025-10-08" version="1">MGAQQPYLYDLDQRDYRFPVKEFDPKVITRQSWEVKPQSPSKMVLYAHEVPTGRTSRMRPMGGTAKWWILFSRKVQIILRVFELVADFGLLALMILITKVDPITQWVLRITPGVVAICSAYAIYHLWQPAGARPPASSAAYQMFAAFTDLAVLPLYTFGGMAIVNHGKEWANLTGNDMLTANYFVPAAYYTLIGSGGLHVVSLALSLWLGFMFRRISHMPPDMNPLEDHLTARHKRNKSSIATSYMSENSKRFSTPLEEHRRSGAPYEDDLSRPPSIPFMHTRSNSGDSLASMKRDSYVNLPDRQYQVAPGNSPRNSTGSAGDPRRLSKAPGPSHRGSYTEIPLQDTGANQTSRPGSAAPESPANNNPTPARPARFTEAWYASESLVNRTQERARKMAAASKKAAPKTGAYEPVNQRYNLANSDGEGSDQENIGNRMMGPDDVSDFEDDIMNDNSMHPNPLRSNPSHPSISSISSSALGPPPKPPAHGNTNLPRTKTPYRAQRGSALAEVSQNSRSVSGSLDITDQQKPAGLTVPNTWQGRNRDSSIQPEEGMFYAKAYGDLKAATPPIMVGNPRQVSSGNDFDLGGGGGGKYRRNVSGKVAEEGRAYSRYSILNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W952</accession>
    <name>A0ABR1W952_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T2</fullName>
            <ecNumber evidence="2">4.6.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007842</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the RNase T2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.19" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667499.1">
        <property type="nucleotide sequence ID" value="XM_066812157.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045217"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240:SF17">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045869984" description="ribonuclease T2" evidence="6">
        <location>
            <begin position="27"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="99"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="334" mass="36363" checksum="AB50B15100C2B3E4" modified="2025-10-08" version="1">MPNTRCRRITAGAAIAASLFVHKAVAGLYPGMSNLNHTCSLVDPILSCSSGASDPSAVDTCCTETFGGLVLATQFWNTYTGFESEGQVLPKDAWTLHGTLPSPRTVSPPTKEKTKNGLSTTPSPHPTPRPARRTGRPSPAWRGPDFGTFLAPLGKLDLLAWMGVHWVAQPGWRNGDFWGHEFSKHATCYSTFDIECYGPQYREHEEVADFFETAAAFHRRLPTWAWLEASGVRPSNASTFSLADFARPLTQGFGAVPYIGCAGPKYNTTDAGKGSSDAGYTVINEIWYYYHVYGRVQRQQGLAVDANITGGRLTNCAQTPGALHYYERTAGSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9C8</accession>
    <name>A0ABR1W9C8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667497.1">
        <property type="nucleotide sequence ID" value="XM_066812155.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045215"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="75" mass="7960" checksum="5CE26F14E54A4ACC" modified="2025-10-08" version="1">MEQDRKNLPPPSGLVALVNTAALGLMRSKCNARVVSEVGGQGHSGIMCLRSDIGNSRARRGDFRNSFGNGEESAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA99</accession>
    <name>A0ABR1WA99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667920.1">
        <property type="nucleotide sequence ID" value="XM_066812578.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045638"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="515" mass="56857" checksum="BD6A9740DC2B7616" modified="2025-10-08" version="1">MTLPRVIKPLETKQDRVAKLASHLAQTERLRHIWLADAPPHYPSIYTASRVEKLLKEQIIKSREKRREARVSANPIADGRVPKTIQKLLDRWPLPLAVIAFTPRPTYFLPRNSPLRGAVAKGGVLSRLRLLFPRLPQGLGSAAQSRWDVFANSKSETATTAATTSPEEDAYDHVYETEARAPVDGRMPPFSGPGRLMLWTVADLHQPPSQEYRDGQRDNDMFSWAEALAQTTIRLLEQEFGIKARSDPSYSGLWVRRGRGDDAPERQIASIWPHVDEETNIVTAGITLNVGLPREVQILTEKEEMKESATASWSGAQPFDPDDGTTSIAAELAAKPASFNPKDRLKSDIIRLGKTLPVRQLGAPPRPRPPPAAPSGTRAPSRIAPPPRRAPRSAWTTTASRSRGRTSWRGCWGSATRASTTTATPAGPRARWHRHTSRPSRRPPRRRATSFFVLSINKREETCASADAHTAARLQDASTRQGPRQAAAWGGGGGKTSRGCCSDAGTHRKFRANDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAH0</accession>
    <name>A0ABR1WAH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF726-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007278</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMCO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666935.1">
        <property type="nucleotide sequence ID" value="XM_066811593.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044653"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF22">
        <property type="entry name" value="DUF726 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="75"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="666"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="666"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="733" mass="79536" checksum="C94F448FA5D1EFC9" modified="2025-10-08" version="1">MLSGIKKFAGGLHDGQDHHEEKAKEEQSLTTILSTREDRASLLLLVVECVEAMRQQLVNNFEAGDVAEADPTKLEMSAQSQNELNVSDEKAADQPAEQKPAEEGAAAGKEDSAEEKSRKQAQKRREQLTKALAKDDFVALKKSSMAHFDQWRDSVLERVGEIVNQTSDDEDPDIKKAKNEELRRREDGQPQSTNPSGSAAAALHDDDGGLAQLQKMYPPPATPLRDFDDAHRVLVLHSLLLLVLGLETYQSESRVLMLRLASALAVPPRILAEDEGSVAKGLLEAAKHMDADEQKEARVDKNSKSRKWKVGLGAAAGAVLIGVTGGLAAPFLAAGVGTVMGGLGLGATATAGYLGALAGSAPLVGVLFGAYGGKMTGQMVDEYAKQVEDFAFLPVHPGGKGKDSDTRHLRVAIGISGWLLLESEVVDPWKVFLASRTEAFALRYELETMMNLGNALTSYVASYAWGWAKKEIISRTIFAALASALTLPYGLAKASRVIDNPFSVAKSRSDKAGAVLADALIHKVQGERPVTLVGYSMGSRVIYACLNELANRSAFGLVESVCLIGAPVPSDTVSWRRIRSVVPGRIVNVYSTKDYLLGYLYRTSSLQYGVAGLQTVRDVEGVENVDVSDLVDGHTQYRFLIGSILQKVGIEGIDAQVVEQQMRTFRREQEKKKKNEEEMEKEEGGKSPEAEADAMEKEIEGKASEGKAAPRMEIKRKEVPKRASESKVFTLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAZ6</accession>
    <name>A0ABR1WAZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein HGH1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008483</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HGH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668140.1">
        <property type="nucleotide sequence ID" value="XM_066812798.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045858"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039717">
        <property type="entry name" value="Hgh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007206">
        <property type="entry name" value="Protein_HGH1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007205">
        <property type="entry name" value="Protein_HGH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387:SF9">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04063">
        <property type="entry name" value="DUF383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04064">
        <property type="entry name" value="DUF384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein HGH1 N-terminal" evidence="4">
        <location>
            <begin position="95"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HGH1 C-terminal" evidence="5">
        <location>
            <begin position="283"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="332"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="348"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="362" mass="40926" checksum="B60F745CA581135C" modified="2025-10-08" version="1">MPTELEELVGFIANPSQQIRLVAIENLVPFSTSQPEVFKADKFVPIKNLKLLVKDHPQIAEHVITILINLSADREVLENLATDEKFLDTILSFVTLPNEPNANLLSMLLANLAKWDAFQSILARKQAPPKELGSDDLVMNQLMDLFVKGAEGTYNKDADYDHLSYLFADLTKHAELRQYFVRRQDYDGVIPITKLKVFTEHKSSVRRKGVASTIKNVAFDVPSHPAFLDEDDINILPYVLLPIIGNEEFDEEETMAMLPDLQLLPPDKERDSDTAIIQTHLETLLLLTTTRQARDLMRTVQVYPVVRETHKKVADEGVREACERLANMLMRDEEDMATQAPIETTAGDGDDDDDDDDKVVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB70</accession>
    <name>A0ABR1WB70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">30S ribosomal subunit S4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008562</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668219.1">
        <property type="nucleotide sequence ID" value="XM_066812877.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045937"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_uS4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="8">
        <location>
            <begin position="133"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="191"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="327"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="328"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="50843" checksum="11C68362FD7CE8D8" modified="2025-10-08" version="1">MPRAAQRRLHVLRRPKLRQSWSKYNLYNLWRQRDPKIGFTDHETFFQQKWRAKGLLRAYHGEHIKERDWERMFSRRLLSVANMNPQYMAQNDGSEMAAGRGSGRDIVSKWKDDKVEPKPITPYMNMAFAPMERRLDIAIFRAMFASSARQARHFVVHGKVKVNGKVMHYPAYKLNPGDMFQVDPDSVLFATGQPKKKGGSSARQAITNPQDNAEAEPAAEEAEGAEAEAAEATEASEVPEQDPETTDKPEAPKADMKPTRQAIQKLTKQAKSILARDRDVSTSQKQNLRSFLKRAKPLLSKAGRSTATPTDILDELNSMVKELNLSDAPAEAAAEAPSTPEQAVAARHEPPRSIEDLNADELKALQRLIKEEEENPADPTKPYHTPWKPRDYMSPFAFIPRYLEVNQNVCSAVYLRHPVARVNSAEVPTPFGYQINQLAFNWYLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBE2</accession>
    <name>A0ABR1WBE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008636</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668293.1">
        <property type="nucleotide sequence ID" value="XM_066812951.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046011"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF22">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="62"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="498" mass="56345" checksum="C7380AA031816686" modified="2025-10-08" version="1">MCLIAFVSTNESIPLWANRKNDRRRREKESHRCHPGDSDTDVPGGNAPVNEKKLLRKLDYHLLPAVGVLYLLSFLDRSNVGNARIEGMLDDLHMTGNQYLTGLTLYFVAYVIFEIPCNIILKRTSPRVWLPTLTIAWGIVATLLGIVQDMPGFFVARFFLGITESGLFPGVVYYFSMWYKRRERQYRISLFFSAASLAGAFGGVLAYGIGRMSGIVWANGWRWIFILEGILTVLVAFAAYWFIHNYPKTAKFLTEDERRYIHQRLTADSDATNDEKFTWSAVSDALKDGNCWLYGLGFHTMSLPLYTLSLFLATPPPSPNSSPSPLRLRLPDHPRPRRPLRTHRPARPLHRRLLPLRRDRLLHPARQHVAPTTAGVSYLGTFFAAGGIYPAVALVLSWPAINVSGQTKRAVANAMQISIGNLGAVLGTQLYRSTDGPRFIVGHSFALAYLLTNVVVVSLLWWRLRRENRHRGEAGVPVVVEEFSGWKGDADPRWRFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCV3</accession>
    <name>A0ABR1WCV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667459.1">
        <property type="nucleotide sequence ID" value="XM_066812117.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045177"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WSC" evidence="2">
        <location>
            <begin position="170"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="497" mass="49777" checksum="5EBA23D46DB43CAF" modified="2025-10-08" version="1">MVSLANKDRKTAGLPGNIRCNYASPVSDATSYGDSFNAQGGGIYALEWDSDGLKVWHFPRSAVPSDIAYAPLTSPEPASWGPPQALFGGSGLVININLCGDYAGNIWGKTDKCDTLAPTCKDYVASSPKAFLGAIATTKQYANHHIDHGDGLINTYQVRGGLSDPATINGYTLLGCFGSSSGYSTWSSASEYATMDNEACVASCAGRKYSGVFATTCYCADTLGDTSAVENAQCDRACPGNPNESCVATLRPLSRRAAPANILLTVYDNLAAAPPPPGAPAMGGSSSGAGGNSTATGGNGGGVGGVGSTVIITTAVTMTYTTVCATNPAQLVTVAYCTTLTITTCSGIKAPVPTAAGAAVVTGGLGPFWNGTSNGTAQAAALAAALVPMTTYAETCSACGPRGANTVTLTVPLAVATAAKADVVVTAIAVATVMPVKLGSSNSSRPFSNDTNGTAGGVPPTNQLAVVNGASSAFADDFVGVAGMMLSLALLGAVFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WD78</accession>
    <name>A0ABR1WD78_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667548.1">
        <property type="nucleotide sequence ID" value="XM_066812206.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045266"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="573" mass="64202" checksum="8420F1FA1954744C" modified="2025-10-08" version="1">MAAYTYHHHWQDDDGRDGLIDFEQYYTFPSHPKNHAGGQGLFNRLLKRQYRQVDDSYQYAKKKQQLASQSSKSLSQSQSQSKSRQWGADLRSEQPCPAQGSPTTPAAMRAFSSSSTSSTNLKPRHKQCNPDQSPRPSAVGGAPPASPIATTTAADQQPNIFSRLLRRAQSKKALKPARLDTAEKHHAAPPLPAAKEPRDDVAVAQGEDSQGTVAMDRKPTLRLKKSIRSRFRGPEQPPRQPEATEEPRKPSAVYVPRHAAADFTRTAVPNSDAAARFASFDDARRRLSSSSQAPVSPTLHRPRTSPGHHHNPNKDEEDYFQQPQQLLQPLQPQQSNHAKRRSWAPSNTESRSNRFSFASYNTEADYTTAAAPKAAASSTTVDDHEALLLPPSSLDQAEQQRPRQSKRHSYRLVPDPHDAVIEEETDFQRFLNQAAEEDRRYRQDLWRTLSQRSRAAGGAGILPPPVVIGHDAADEFDLQVLLGGADWTTTKPQESSRERSNSNKRASNSHRKRASVISYRSQTDRTKQQLQLQQDMDNAPPLPLAESKANRRLSMTKRVQEYFKPEGVVNFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDF8</accession>
    <name>A0ABR1WDF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008027</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667684.1">
        <property type="nucleotide sequence ID" value="XM_066812342.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045402"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044982774" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="24"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="28"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="487" mass="51030" checksum="FEBC2FB05D0AAA04" modified="2025-10-08" version="1">MKPSSVTAPLATSLVALVANAAANAPATATLNSGVVLGTQKTFPGADTAVNEFLGIPYAAPPLGALRFALPSPPKSWSTPLNATAWPNACIQQGNTDVLLAPESEDCLYVNVFAPAPASPSAPNAGQSGGRAVMVWIHGGGLKSGSASMARHDGTSFAAHQDVVVVTLNYRLGPFGFPISPAVPRSEQNVGLYDQRFALQWVQENIAHFGGDPSKVTIFGESSGATSVSRLVGTMNDTSSRPFRAAIQQSGVYESAWVMDPPGDVIGPAAWPLLVKSLNCTSSKGNSSSSKISMQSSAEAAAELDCVRAAPADSIRALINDPTAFLSFYPVDDDITQLSNPDRARAEGHIAKIPLLIGTNANEGTMWTGSWTDLNSYTAAFPMLAPYAASLNTTYPLGGRGPNGELLADGWHVNAAIDTDMEYTCPASRVAQDAAFHLGLPVWRYWFNATFPNTALRGGARGLPLLRDPHRVRIVPAGQRDCGGGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WF51</accession>
    <name>A0ABR1WF51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668616.1">
        <property type="nucleotide sequence ID" value="XM_066813274.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046334"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8081141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="37886" checksum="EAB9053805BA16F4" modified="2025-10-08" version="1">MFSKNSKSNSNSNLAPPAVLITPATACEEGGRCSRMDFVLEAQHVRQFVVTWGRDAEKLKEPYKGRLEGFRLGSKAAKYIQRFAEKDTGSRIVLSSNDNSEENCRCDLPLLTELAWWFSETLKSEKPERRVVRYFFGTKPSDGGEGKNKDSSNKADAKSKSDKEALDFLYSIIWQFVRAFPHGQTSAQGVVISALPEEVSKTLSVDEFRAQVKKLDGTMSTFSEALDLLWICVQVAGDRITYVLDGLEPVARDRNNKATTPPRGYDPVLHALFESSHSKVHSVWVSTKENSGVATACKFQKDAGRPEKEFGLEPSSSDSLLRSWRTVSELKFRGNRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLF6</accession>
    <name>A0ABR1WLF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668787.1">
        <property type="nucleotide sequence ID" value="XM_066809864.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042924"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="301" mass="34824" checksum="785D98290535610C" modified="2025-10-08" version="1">MASYLRGVLGLAPASMKPSPKYESLRGEGSEPLLDEKGDEVLEAKEPSPWYRQWSTGAFALSLILFIVSVAYYGRKLSAVASDNVCQRRMWPGHPVQMVLDWEWRQYDSDIIPDELFGDGITGERIETWKALYDFGIFQDGAVGFELNKLPRINKSLDEAWWTRPPPFNDEVLSVMEVTHQLHCTTWIYRYIYRLQWDSATDMNITDLVFQLHANHCFISLFTMVQCQADMTPVLFQRDSSGLGAWKTRDAPHRCKQYERMTEWQKKNQICTLQCSEDDVLPGGAWESAPRDKFYWDSISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLL1</accession>
    <name>A0ABR1WLL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668900.1">
        <property type="nucleotide sequence ID" value="XM_066809977.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043037"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="227" mass="24267" checksum="1404E0E0BB24C126" modified="2025-10-08" version="1">MGCSFDRLNIVENWIGRKKVLLMPTVGMVSCEAFRLLVSWQLGRISLRVIWTAPLFKPLGGGDALAVLLVIVPSVTKILLSRFGVATGRQGLLFLSTSADMITAGTLLLRVANQIGLIVSSLVVFALENGLVTVGKSLLMTLGSAEMAETLLSAMNPRASVGAMLAGSLIVVAFNWGLKQGRGIWLGAPLLLVTVLYALALVSMRAIEVLEKCQQIYDDVAVARRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLX1</accession>
    <name>A0ABR1WLX1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005806</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669044.1">
        <property type="nucleotide sequence ID" value="XM_066810121.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043181"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052415">
        <property type="entry name" value="Diphthine_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042:SF1">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="409" mass="44878" checksum="EC6005AA4DD960F1" modified="2025-10-08" version="1">MEQARLITSRQSLTLELPPSCIEFCPASPQHFVVGTYNLQKEEAPAEEGDAGSDDDGDTTQVATRQSQNRNGSLVVFQLDDDDEVRHVQTVQQPSAILDLHFHPQKGKSDILAVVSSTGTLSFFKLEASQRDASATLTELATHQPLGGDGNTLFLSCCWHPVLPNMISVTTSTFEVHVFRLDEAWNVLEASEEPVLAHTLEAWTVAFSPALHEVTDQRLSTIYSGGDDSMLLQASCNIQIDTPHIDAVHSVIKMKGHGAGVTAIIPLDITFENNARVVLTGSYDDHLRVYAAYESGPETMAMRAQLLQEINLDGGVWRLKLVSLNKQGDCWEAVVLASCMHAGSRVLRVMGSPKMEECAVEVVARFEEHKSMNYGSDFHPGSELPGGDLKVISTSFYDKLLCFWVLPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMV9</accession>
    <name>A0ABR1WMV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668861.1">
        <property type="nucleotide sequence ID" value="XM_066809938.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042998"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="562" mass="64182" checksum="12D5E583EA16B7C8" modified="2025-10-08" version="1">MPRGTQGQSRPARTALPSSPVESSIEANPDSRSSSSPDTPSSTLSRTPANSTAPSTPAGLTPATSDRRSTRTDASSHLPLFDVNVIHRIKGNETIDCRKWDEYLPRLGWADSLFGSLRGTVAERYSTIKANTSRQERRRELREIQTRNLLINAREIHCKTCGACGSYGISQKCPRKKDATLVQHGWTEVEHYFDFYRPEVPSKHEVTARYSRFRIQNNVEVKAVKVLDHMYPYMSYQPGEYVLQLMRMSEATERQQAIGIRVEDQRDGYMDFEDDILVPDGTVPFQPEEDLERFNVVRDKILRIVVAILGFKPSTTSYVPKTLNALFEPSELPYQQWEYLVAAWDVKFQKVARLPKAIKFSVNGARDNFSEAAWLIRRLRAEKKLMEDSLDRESLFQLLEKLLCRMTEIEFDKLADQYLKRLGREAFDCLKDGDEDKVLVYAAGAFSEDFKDIHSYYKTYSGYPQPAPFDEERLDEFRIAALRIINDQDFVKAVLTQVSRQLAKQGRYLDEDHDESIATLPAGAESPEPSTSAQPESARKKRGRPPKKEGDPKGPYKRREKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPB9</accession>
    <name>A0ABR1WPB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">laccase</fullName>
            <ecNumber evidence="4">1.10.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_006603</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11276"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17594"/>
            <dbReference type="ChEBI" id="CHEBI:17977"/>
            <dbReference type="EC" id="1.10.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.2" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669841.1">
        <property type="nucleotide sequence ID" value="XM_066810918.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043978"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13854">
        <property type="entry name" value="CuRO_1_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13901">
        <property type="entry name" value="CuRO_3_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF87">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045869999" description="laccase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="13">
        <location>
            <begin position="86"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="11">
        <location>
            <begin position="207"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="12">
        <location>
            <begin position="422"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8085332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="583" mass="65024" checksum="FE16F6324D9DF474" modified="2025-10-08" version="1">MWALPSLTGIASISLFVSLCAAAPAPALEVSEIKTRAASTCNTPDNRACWTDNFNIQTDYETSTPPAGSAPKTFDWEVTEQDNWETPDGRILPKVMLVNGQFPGPTLQADWGDDIVVNIKNSLRTNGTSFHWHGIRQFHNNIHDGANGVTECPLAPGKSKTYRWRATQYGTSWYHSHFSAQYGNGVWGPIVINGPSSDNWDVDLGPFPISDSYDQSADEIIHFTQTAGAPASNNVLFNGTNINPEDPTKGRYARVQLQPGRRHLLRLMNPSVEHNFHVKLVGHQFRVMATDMVPINPITTDSLFMGVGQRYDVMIDADQASGNYWFNVTFPESKLCGTSLNNFPAAIFTYADAADQDGLPMTQGQPLNDTSCQDRTDFAPVITRNAPDFALDPNRDLKITLDGPPFLWKVNGSDVNVDWDRPVLDYVLEGNTSYPRRENLYIVNERDVYTYWVIENQNALPHPMHLHGHDFLILGHSAPQGEPTAFSGGQLNLVNPTRRDVTMLPGNGWLVVAFRADNPGNWLFHCHIAWHVSSGLGVDFLERASEQADQISQQDLAEYQQTCQEWRDYFPSQDPFPKSDSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPM3</accession>
    <name>A0ABR1WPM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">H+/oligopeptide symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006693</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669931.1">
        <property type="nucleotide sequence ID" value="XM_066811008.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044068"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="559"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="601"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="601"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8085422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="631" mass="68551" checksum="B63588B0ADFE5C20" modified="2025-10-08" version="1">MADTSTTLTNRNSIGAVHAAPHDADAVDAVISDAKEVHEVQLAGAKEERETFHGLILPTPEEKSTLRRVAGKMPASCYYLCAVEFAERASYYGCNQVYKNFIRAPLPPDGPGTGAAGSLDSKYGAGALGKGSSTASAMTEAFKFLSYALPIFFGWLADTKYGRFKMICWGVAICGVAHIIMIISALPPVLQSGKAMGPFALSLYMLSIGAAQFKPNISPTVMDQSPHKVAHVITNNKGEKVIVDPEESINSVMLWFYLLVNIGAATGIATTYLAKGVGYWAAYLIPTILYLMLPPLLWYLNSRLVKQPPGGSDLGNVFKVLGDILTHGGLRSIGRHGFWEAGKPSVRRAAGSTKEYGYDDVFVDDVRRTFQACGIFIFQPIFQINDTGLGAAGNALTAGMENSGMPNDLLDNLNSVAIVFTVPLMNHLIYPLLRRFNIHWGPISRMTFGFLLATFGSVGYSVLQYRVYQTSPCGYNATTCAELVPEGENPLSTVPIELYSIPVILGACSEVFINVTAYGIAYSRSPKNMKGLVASINLFMTAIQAIIGLATAPAVKDPYLIWCFAGPTIAGFVLAIIFYFTFRHIDKEEFVINTDFGDMKRDSEADSDVERAHRNQGQPQLLTEEKKGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPN8</accession>
    <name>A0ABR1WPN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cerato-ulmin hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670026.1">
        <property type="nucleotide sequence ID" value="XM_066811103.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044163"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23508">
        <property type="entry name" value="hydrophobin_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.120.10">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010636">
        <property type="entry name" value="Class_II_hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036686">
        <property type="entry name" value="Class_II_Hydrophobin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341:SF1">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06766">
        <property type="entry name" value="Hydrophobin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101751">
        <property type="entry name" value="Hydrophobin II, HfbII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046499456" evidence="4">
        <location>
            <begin position="18"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="100" mass="10188" checksum="E4167F5415889650" modified="2025-10-08" version="1">MQFFTVAATLFSAVALAAPGVQVARQANYTPCSGLYGTAQCCATDVLGVADLDCANPTETPASADNFSEVCSAIGQRARCCVLPILEQGILCNTPAGVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPT9</accession>
    <name>A0ABR1WPT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006753</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669991.1">
        <property type="nucleotide sequence ID" value="XM_066811068.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044128"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="116" mass="13023" checksum="40A2873359BA668B" modified="2025-10-08" version="1">MRYGSDIPSYNKEDEARFMEANRDLPVTEKFMLGQIFECKAVSTLTPLHEYVYNKCFFRGANGAIESCAEAHPALHLADLGEEGPAGSSGKKFLKTSRLDSVPLPNRPKEIFRCHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQB3</accession>
    <name>A0ABR1WQB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">L-asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668707.1">
        <property type="nucleotide sequence ID" value="XM_066809784.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042844"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04701">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF43">
        <property type="entry name" value="ASPARAGINASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="500" mass="53953" checksum="EA77E4E585CB7BB1" modified="2025-10-08" version="1">MEYKNQQRIPKAVPRLIIHGGAGNIQPENFSPEKYSQYREALLTITSQTEVYMHTPIATKSKGAEHTREPTALEIAVHAVTLLEDNPLFNSGHGAVFTRDGINELEASVMVSRGKAKRGVGVTGLRRVKNPILLAQKMLEHGEDDLTGKSDLGWSSSRDAGDGVNLDIPSAQGHTLIHGPSAEILAEKYGLELAEPGYFFTRTRWDEHVRAREREKKSRIHFATWSADEYLPQGTCGAVALDSDGVLCCATSTGGMTNKLTGRIGDTPSVGAGFWAEEWSEQVVASSSPTARASGMSISDYAPLWWKHLAWPGRAISDLRTGLVGGLCYSDCLPGQPQYSPLSREQATTTKTVTRSVAVSGTGNGDSFLRLAAAHAVVSMARWAAIPAGEALRRVAGRGGALQKSADNRWSKTGEGEGGMIGIESTREEAQAEEGGRGGGSTVVSSKILHDFNCGGMFRAWIDDEGNHRMKIWDHVADEQDLLRKHAEPPGSEKGQVRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRE7</accession>
    <name>A0ABR1WRE7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006943</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670181.1">
        <property type="nucleotide sequence ID" value="XM_066811258.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044318"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11577">
        <property type="entry name" value="GH71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005197">
        <property type="entry name" value="Glyco_hydro_71"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03659">
        <property type="entry name" value="Glyco_hydro_71"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="277" mass="30312" checksum="71B0E8D00AA4F5C8" modified="2025-10-08" version="1">MILSFDYAGGGPWSGINVVQAINQFSAYGSYFHEGGKPLVSTFEGPAQAQDWELIKKKTNCMLLPDWSSLGAKQAIDASKGVIDGLFSWAGWPWGNMDSNTYVDASYIQFLEQGGKDYGKDLKFSNVPSWPYSWNDFGESHYIGPLYVDGDDYEAFTVGKAPFNYAADMPHDGWRLFLPFVIDLYKNRKATIENEGLSVWYRPSPAAACGDGWTVGNTASQLLLEFPPAEVAQDKIFFSALLAAHQSVTVTVGGVQVAAEWTSQPAYGSGMYHGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRJ2</accession>
    <name>A0ABR1WRJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669729.1">
        <property type="nucleotide sequence ID" value="XM_066810806.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043866"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046971526" description="Secreted protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="9831" checksum="CC55DED6161CF820" modified="2025-10-08" version="1">MAPLKTKILTALLALAPFSATAKAVAARDAARDAARDAASTSTVTTSCSTITFTKTVPYSATSSTPAAVTAGAAEMADMLGMPVVFGVAAGAAAVAAGMVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRT3</accession>
    <name>A0ABR1WRT3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669562.1">
        <property type="nucleotide sequence ID" value="XM_066810639.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043699"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020915">
        <property type="entry name" value="UPF0311"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315:SF1">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11578">
        <property type="entry name" value="DUF3237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045090209" evidence="1">
        <location>
            <begin position="25"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="176" mass="19194" checksum="6039302F70C251EE" modified="2025-10-08" version="1" fragment="single">SIHNIKMRSFFAPLLAAFATSVAAAGPTPPGFEFLYTVNATLAPGIQIGPGPQGDRQAIPIIGGEFHGPKLNGKVLNLGADWGLTDQYGTFHPDTRYHFQTDDGANIFIRTSGPAQKDGTIHLHCLLETGHPDYYWLNNVVAVGILNGGTGYVVIDVWQVRYVLPRGQRQRKTLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXD9</accession>
    <name>A0ABR1WXD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670705.1">
        <property type="nucleotide sequence ID" value="XM_066807087.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040147"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="328" mass="37021" checksum="841E29BAA29D670E" modified="2025-10-08" version="1">MHELKNILAELDRGKANQNPNGKWGFTIYRTDWKDQRLWMDYKRHLRDTIAVAPKADDPDTDANTELDKEAKARKKLSKRIRLAFKLVVVEDQVLKGRTTAEVRQYHREKVRAYLDDKPFRFSGFPGEEGEEDGAGEGIDGSHAEHAEVKVEDDEQVEDEKPQDEQPEQLPPTPPQSSPPNQGEAADEAQTNPPPAPSPPREEKRVGHVWQDYFVHVNEVVLAKYKAAREREKLLLVNPAIYAHADNDTLFVAVVAEAERFDYRLQRFGPWEGDGSVPEARMAWQYVQIGRLPVLYDYLSRRPLGAAQLGAIPETVHSRGGGGGGEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXT8</accession>
    <name>A0ABR1WXT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670875.1">
        <property type="nucleotide sequence ID" value="XM_066807257.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040317"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="243" mass="26542" checksum="B233D87EF98A1C2B" modified="2025-10-08" version="1">MSIPDGGGGGVIEIYTLQPPDALLQLLSAHLPHSLSLLRRLQFTKFPGGVTEHARILYASDAALPSPTNGTGVTAATERDEQHQQCHHPFTAAYLDISRGPETQMWMYSTLERCGSSSGGEVEQEKKEKRQKALHHAVSILRAARRIRDYHVATPSQSSPLGPCILAGTLSEALRIALRDEAGVASSHVSLYDKWLLDVRELPLVGNSGNSQTPLLEPGMRWGAVRREDIALVLSRSDVPRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY05</accession>
    <name>A0ABR1WY05_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670937.1">
        <property type="nucleotide sequence ID" value="XM_066807319.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040379"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="127" mass="14874" checksum="7703CE16E1FE5982" modified="2025-10-08" version="1">MTTAPSSPRRRHILSSINPDLPRLSPEVEDRADSYHTDTAPPKSEPHLPDDDASEERARSKDPDSSNNDGKRHGDRKTTKFRFKSKHSSSHRSSRRRERDYDDDDRRHRDREGRRRSERSRDGREGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY95</accession>
    <name>A0ABR1WY95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003097</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-beta-HSD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671030.1">
        <property type="nucleotide sequence ID" value="XM_066807412.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040472"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF51">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="3">
        <location>
            <begin position="79"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="494" mass="53340" checksum="5AE56CB81D215B7B" modified="2025-10-08" version="1">MEWLQAHPFATAAAAVFTLAVLYFWKLNLALTTTPPEVLALSPHRWTKQEIRATYERLERAPLRWTAHLPPARPNRRYVVVGGSGGVGGQLILHLLERGQSPESIRNVDFRAPARPDMRDGPASRVDFVQADITDAASVDAAFAKPWPTTAGNDEAKGPMGLTVFHTAAMIVPHERCEATYDRVARVNVGGTRHVLDAARKAGASVLVATSSASTALRPVGYLSNWFRRWPRHYVQVLDEADFDQPLRPHGEYFGNYARAKATAERLVCGANGPDFRTGVIRPANGIYGTSVGDQLVGLCLRSGSFPSWIPNICQNLVHASHVSIGHLLFEAALLDHNQDDNDGDNLPGCAGRPFVITDPNPPPTFRDIYDVCETLAKTPCKVQVLPPAPMLLIAFAIEVCDMLGRQLPSLLGWLRPQGQIAMLQPATFSVSTHTPATDAAAQRPVAAGGLGYRGVYTTLEGPASSSNGGLGDKVETMVKDVRNVATMPNAVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYU9</accession>
    <name>A0ABR1WYU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671242.1">
        <property type="nucleotide sequence ID" value="XM_066807624.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040684"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="95" mass="10699" checksum="5C720569D1CFE00F" modified="2025-10-08" version="1">MTNAESTRADHINAAQDLPRRAARPFKEAEDPEASLRNMPSLGNRRRGLVRTQNKRAEDERKMSGSGTERSCGAVHDVRETHRIKQGGDSERDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X019</accession>
    <name>A0ABR1X019_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671671.1">
        <property type="nucleotide sequence ID" value="XM_066808053.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041113"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047207397" evidence="1">
        <location>
            <begin position="20"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="134" mass="14178" checksum="F7C805CCE8512C73" modified="2025-10-08" version="1">MQFPTILAALVAAASFSSAAPTQQLAKRELGGVLICQGVNATGPCHYEVYSMQDCHDLPGNLSGNAATFAPDGDNFYCYPRVGRCSDICTSPTGCTFGAVSFSSPVKYDLTSIQWNTLIEAFHCYDNSTSTAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0L5</accession>
    <name>A0ABR1X0L5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671794.1">
        <property type="nucleotide sequence ID" value="XM_066808176.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041236"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="767" mass="86508" checksum="C251A4A1E5A54345" modified="2025-10-08" version="1">MNSYNPRKRRYSGHEGAPAVLVSQDPHAFTPASTAQSPLASLSHQDLQILGQAALILQCPVSQLLDLDRNPARFTTSSSSPPYPEQKRLRLSTDLQPMPAHEIPSSSSETSHHRPPVNPPGSARRDGFSLGISGSRLAHYFAGISVCPPCSTCEPEGYSGIPASSQFDDNERSPPLMSEKSPPSSSQAWTLPPSQANLFPYDEANPAQLMSSYPILQPTQPTIVQPSTRREGMVYPVTSSLEEYTVPVTAPVVRPPSQEESTAPPDNEDVQYPSTSCFNKRHESDASHYPSSVGLSSPVDEKTFSRPEHHNLGIATSYQKAPVSKRGPFKNNEVREQTAETRRIGSCIRCRMQRIRLANGRLQCETNPVDKQGTCLTCAKVSHAKVSRLPCLRYKITDVRLFKPGQIKGHEWTRRWQEGVADDISNWASFETRNVGVTEGYTHQPVVLRVRQFVPQEGDSLERTWVYNGVRRSVKIPAFAIVNLEEARNAYEDHLTRSVKDFCRNVVSSKHKLIWGTYAAALKAAMADETDEKQKTLLRKALRLWMAIRMTTKSTYIVGQETLGMTRDIMDETSPLRGQIPLPPVMGAQIELILIHQIQNKLRREMLDELQGILQANNHITWFTAYLVTFIFLHNVSLLCQHDAAYARKHGITARFARENTVREYLTAGSELTLDLDDKQGPTYFWRTSTTATKPGMYPFSAECKDQDLRTLAQLDPVKIKFINVTRNIVKEQGKHWDEVRRRDDYEDDFYFISQLYEENWAPRTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0T8</accession>
    <name>A0ABR1X0T8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003974</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671907.1">
        <property type="nucleotide sequence ID" value="XM_066808289.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041349"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="52"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="476" mass="52918" checksum="7A160EF1D6285229" modified="2025-10-08" version="1">MATIANTKDTKRKSAILQVKSFVNRFLKYHRVRDPASSISGPMDSTELPPTIAILGAGIGGLALAIGLVKRGVAVTVYEAADAFSTVGAGIGFGPNSLNAIDLIDPRFRQEYDKAKTANEKPEFEHSVFDALYAEDGFGTRRGWTKGLIGAPYFTRSSAHRKDLLDIMEKLIPPDTVTFNRRAKSIEQVGSKVIINFFNGETVTVDAVIGCDGVKGITRGLVLQDTAPEQVKPTYCNMYIYRGIIPMDEAKEILGQHAGDAKWFMMREKGVAIYPISQGKEENFVFFVTDHNPWKQGDSPVACTKEEMLEDLEGFDPRLLKLLDWAKPLKWPTWHHPQTTTYYKGPAGAGQGLEDAVVLAHLLALVKTPDQLEYAFEVYDSIRRPRAQRVVSTSFEAGIIYTWLDPEIGDDMSKIVENANQRLHWIWQHDIPGDLEKAESEFMRFVSSSNCNIQTSMPDNKIHPAMKSSEIAASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0Y6</accession>
    <name>A0ABR1X0Y6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">ER membrane protein complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004037</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671970.1">
        <property type="nucleotide sequence ID" value="XM_066808352.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041412"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008568">
        <property type="entry name" value="EMC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116:SF5">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010045">
        <property type="entry name" value="DUF850_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR010045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="257" mass="28865" checksum="78A252703917DD41" modified="2025-10-08" version="1">MAQLPPQTIQRDPQLFYWILFPITVVMILTGILRHYATVLMASPPKKVEQPALKEQRSLMHGVAVRSNFHVLTAPSFKARREFLTTAFESGAYLKDPERRGQPPANPMTDPGAMDGMMGMMKNNMAMMVPNTLIMSWINTFFSGFVILKLPFPITIKFKSMLQAGVATKEMDPRWMSSISWYFLCYFGLQFVFNFLLGSDNDGAADAGNGPQAPNMFGPGVDADKQFQAEAENLAVIKHYSVLDDVEQRLLEGIKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1K6</accession>
    <name>A0ABR1X1K6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL39</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004261</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672194.1">
        <property type="nucleotide sequence ID" value="XM_066808576.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041636"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.10">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00629">
        <property type="entry name" value="Ribosomal_eL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000077">
        <property type="entry name" value="Ribosomal_eL39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023626">
        <property type="entry name" value="Ribosomal_eL39_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970">
        <property type="entry name" value="RIBOSOMAL PROTEIN L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00832">
        <property type="entry name" value="Ribosomal_L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48662">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="51" mass="6253" checksum="4E9DD09424D7A5D6" modified="2025-10-08" version="1">MPSHKSFRTKQKLAKAQKQNRPIPQWIRLRTGNTIRYNAKRRHWRKTRLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1X1</accession>
    <name>A0ABR1X1X1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_004383</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672316.1">
        <property type="nucleotide sequence ID" value="XM_066808698.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041758"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06627">
        <property type="entry name" value="STKc_Cdc7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053235">
        <property type="entry name" value="Ser_Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361">
        <property type="entry name" value="MITOGEN-ACTIVATED KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361:SF433">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="57"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="342"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="468"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="561"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1212"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="342"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="468"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="505"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="623"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1216"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1252"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1290"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1319"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1353"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1380"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8089422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1428" mass="157760" checksum="B79339A271701DF3" modified="2025-10-08" version="1">MAPSSGHSSNPSTSSTGERQYHAANGRPAVAARHSGTPRKGSGGRDKAVQDPGLKDYRLGECLGKGAFGAVYKAIHWGTGEAVAVKQIKLVNLPKSELRMIEAEIDLLKNLHHDNIVKYVGFVKSVDCLNIVLEYCENGSLHSICKAYGKFPENLVGVYMTQVLQGLQYLHDQGVIHRDIKGANILTTKDGKVKLADFGVSTSTLSGPDKEAQVVGTPYWMAPEIIELSGATPASDIWSLGCTVIELLQGKPPYHHLQAMPALFAIVNDDHPPLPEGVSSAARDFLMQCFQKDPNLRVSARKLLKHNWIVGCRRSDAPVAKASANFSQAVEEVKQWNKALTSDTNNLRASTGSDSGPPQQNHPQTRSGLNTPAKGPLSLAKPRPTAEDFRSPELADDDNWDNDFATAISPTALQLPLIKPQDHFGGMLSADRLKQFASIDSSRDISGNWDTDMDGELMTMKNFGGGFHEEDPQDKTIRPNWRFPFGPEKTPEPKGQLRVPEPTRSPRKRSTSGHYRRKSQAKSLGNKFELPSRPDLLYREHTVEDYSDLFDNNDQSDLIFNQKISQSRKSPIGGSMRRTASSRPSVLPDRQMQRSRSSIEIQKFAESEGDEDFSDIFGPGDNITEKAESDRGSEDGGLMVLSKLSNNSWLGDDEDEDDPFAFMDPGWDEMDLEANIARDRHARLAEKVEALVRSIKMIEGEEKLSELSEDLLALLWEHAEVKDLIISAHGLLPILELLEPCTVKSRQHMILQLLKVVNTIILDDVELQENICFVGGIPIITKFAARQYSNEIRLEAAAFVRQMYQTSTLTLQMFVSAGGLNVLVEFLDEDYDSARDLVLIGVNGIWNVFELQGPTPKNDFCRIFSRSKILDPLALVLHRVLDEDEGDELIEAIEGRIVNIFYLFSQAENYVKEMVADRQVLKSILKDLHRMTPAHQITMLKFIKNLSMLSTTLETLHSADAIDLLIDLLSGTMKKSHRHFREISNQVLNTLFNLCRLSKDRQEYAAVNGIVPLLLKIMKTDRPPKEFVLPILCDMAHSGSKGRRFLWQNKGLDFYVSLLADQYWQVTALDAIFVWLQEETAKVEGHLINGSFTKEIISCFTNAKINAFDPNLLEPLLKLLRLSPSLSSMLATPEMFSGIGQKLSHKKAVVRLNLLRLVRNILDTRETDYFGSSRDKCLTSLLEDIQTLADKDSAVLVRNLASELVRSHINGESENATSSISSLTASSSAATSAGRARPDSRPGSRRLYTPPSLHSSASTPMTPTHAHRSSQSSAFIEVAHSPKRSAVSITHERDPSLYRPRSRDSTGIPVSSIPRRVSGDLSSSVGSKSRLPRNPGVLPRTSVSDLSDLRRNSLFSNKENQATDGGGGSSGSRYSFVPESPTISSSSSSRRNGSVSSTSTSHSRSGSGKQRRSRAPSEGGAKKWTPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1X4</accession>
    <name>A0ABR1X1X4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672314.1">
        <property type="nucleotide sequence ID" value="XM_066808696.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041756"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050261">
        <property type="entry name" value="FrsA_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946:SF0">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="314" mass="33310" checksum="F12C0E67D617F725" modified="2025-10-08" version="1">MSTASPMVVPSLQPPHVSKTTIPVAGLLVDVYGLDQLPTAATAVSCLWLHHGRLGNKNDMATFAALALSAWHARTNDNNSTGSSSPSRGLIAVAFDERNHGTRLAHKASNDAWRDGNKTHAQDMFGVVTGGYLFGNGASSPGSLQAATLGPRRQAGLIDQHLALGVSQGGHTVWQAMFAEPRLSAGVVVIGCPDYMAIMTDRILFGTREISASPSDVEKERLGSILDARLAKKKFQVLSGGVDKLVPYALAKPFLDFFKSAVETWGKQANISVEDIVYPGVGHKFDDAMMKDAVHFIVDTVSGADATQASTAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X358</accession>
    <name>A0ABR1X358_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP11 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004803</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672736.1">
        <property type="nucleotide sequence ID" value="XM_066809118.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042178"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010591">
        <property type="entry name" value="ATP11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126:SF0">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126">
        <property type="entry name" value="CHAPERONE ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06644">
        <property type="entry name" value="ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="330" mass="36884" checksum="46FD168139A34563" modified="2025-10-08" version="1">MATLRTPMLRNLLGRQLRTVRPAYQQRRWAQVHDVRFQDARFLATSQISRSVTEKYREKLDRKAKEEGLQDVEQLKAAYADKIHEVRKKDGVSIPGLDALLADEAAPQQQPPPPKQHTQTEAAPPTPPPSPKSSSSSSGASIKTLSEILDLDKARELPLKELTAIWRLRHAAQPTSLCAVLPSPTYRAFEHAARRYPNFVLPVPRGAEVGAEMHFLQWVFDAPSQTATVLFTQLAEYKARGEWAQPHTSVTHYWDADLARDQGAVLMAGHVVEGRGATVADAQWLVMLLQKFYGVEALHGTGEKRKLLEAFARGDGNFSVEKLLEESEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3H6</accession>
    <name>A0ABR1X3H6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672829.1">
        <property type="nucleotide sequence ID" value="XM_066809211.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042271"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018824">
        <property type="entry name" value="Conidiation-specific_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052670">
        <property type="entry name" value="UPF0654_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36576">
        <property type="entry name" value="UPF0654 PROTEIN C11D3.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36576:SF1">
        <property type="entry name" value="UPF0654 PROTEIN C11D3.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10346">
        <property type="entry name" value="Con-6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9117" checksum="DA0605C945B40B44" modified="2025-10-08" version="1">MPTDAQVAGGHKATINNPNASKEAKENSKQILENEFNGGDVPKADDNKEKNPGNVIGGLKATTKNPNVSDEAKESAKERLEQMQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3K1</accession>
    <name>A0ABR1X3K1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 4C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004917</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eIF-1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672850.1">
        <property type="nucleotide sequence ID" value="XM_066809232.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042292"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018104">
        <property type="entry name" value="TIF_eIF-1A_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00523">
        <property type="entry name" value="eIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="EIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01262">
        <property type="entry name" value="IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="9">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="115"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="158" mass="17784" checksum="5E3D1C080841E167" modified="2025-10-08" version="1">MPKNKGKGGKNRRRGKNENDDEKRELTFKEDGQEYAQVVKMLGNGRLEAYCFDGTKRLAHIRGKLRKKVWINNGDIILLSLRDYQDDKGDVILKYNADEARSLKSYGELPESAKINETDTYGPNEDGECNFEFGDDNADSSDDEGANAGGKEIEIDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3S9</accession>
    <name>A0ABR1X3S9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mob1/phocein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672966.1">
        <property type="nucleotide sequence ID" value="XM_066809348.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042408"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="38857" checksum="336E0D26E3359D52" modified="2025-10-08" version="1" fragment="single">QRPSHHTDILASVTPASGGTSKAPSGSGQKSSVSSNSGQPISPVTTPQSSQSSTSLAPKIPPLQSSPSLAMGMDDSTVGSNGAGGDDVLSAYHLPRPLPLWLNPGYAKHIVKGNFMTLSARPKTVDQGEWIAHQVVEHYRNLWNFVRVIHEKEEDGNTICNAKTCPRMSAGANHSFTWLNKEREPVELPAYEYITLMQRWISGKIDDTNIFPTDVSGVSFAHNPSITTTPLSQLTNPGERDWVGKRSGFPENFVDVCQTIFRQMFRVYAHLYWAHFIDPFYHLNLEKQLNSCFSHFVLTACALDMLKPQELEPMQPMIDLWAANGTFPAGSKAYEYANHRAGDRLMQLGNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3U4</accession>
    <name>A0ABR1X3U4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenylate cyclase</fullName>
            <ecNumber evidence="3">4.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP pyrophosphate-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Adenylyl cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_005037</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adenylyl cyclase class-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672970.1">
        <property type="nucleotide sequence ID" value="XM_066809352.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042412"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17214">
        <property type="entry name" value="RA_CYR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013716">
        <property type="entry name" value="Adenylate_cyclase_G-a-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055071">
        <property type="entry name" value="RA_PHLPP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF46">
        <property type="entry name" value="LEUCINE RICH REPEAT-CONTAINING DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08509">
        <property type="entry name" value="Ad_cyc_g-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23010">
        <property type="entry name" value="RA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00789">
        <property type="entry name" value="Ad_cyc_g-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="5" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ras-associating" evidence="15">
        <location>
            <begin position="581"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="16">
        <location>
            <begin position="1338"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="14">
        <location>
            <begin position="1678"/>
            <end position="1815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="248"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="430"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1056"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="213"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="302"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="455"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1065"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1103"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8090076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2066" mass="229507" checksum="F6A75051E917412B" modified="2025-10-08" version="1">MTRDDSQARITSFASSSSGRSSMTLRAGAGNESPAPSRSASVSAVSKKATPKPLRVNENGKTIRPFKEDSQISPTSTTGSRTTLSPASTASSNSFFDSRRRSDLTNYRRDLAVLDPAGGRVPQIQKDSPSASPTHNSIPPWLSMPGNGAATSNPPTGFFGTTFYNDSSDALSTASQLSPAFRQGPGDGQRSYSFNRPHRERNYSNATDHTRDASPSSSRPRTPVPSSDVVPFLYQEANDIAKYGEAPVRDMLAGPDKERYADNAAGQIPPKKPRRRHDPVTRYRDDSITGNYAMKDRAGSAGQPSRQRAQSPTPSTSSRLASVDGQTSPGSSHHQGKRGIFDRFRGHKKQKDDTAPSRLRELPQSSRSLVSGSSRTDLTLGEQTPYNNNNKPLPPINQFDQLQGDQQQIQYQQQQQQLLQQQQQLMLQQQSPQQQQLQQSPMSQPPSTQMPPSSRPYQNNRNATFNNKFPFSKKNRAHRPYDDQDEYIGPTDRNDPGKVFHLDTNLSDMEGILAHPPPLTPMDPTLFLKEPERAPEVDRSRGGAWNAPDSWAVRKNADDQAAHAEDIDQSVTLPRPEEKKANHCIRVFRADGTFATIQLPLDSTVSEVMAHVVKKTYVQDGLENYHIVLKKHDQVRVLAAVERPLLIQKRLLQQVGYEEKDRLEDIGREDNSYLCRFLFLSARDSDFTVAPHDLGLGRTTKFNHVDLSGRNLITIPITLYSKTGDIISLNLSRNLSLDLPRDFIQACPQLRDIKFSSNEARKLPISIGRASRLTYLDVSNNRLEEIQHAELHHLSGLLKLSLANNRLNNLPTYFSGFRSLRSLNLSSNFLDKLPPFLCELESLVDIDVSFNSIATLPEEIGMLRNLEKFVMTNNRLANTLPSTFSQLTNLRELDLKYNTLTSIDVISELPKLEILSADHNMISQFIGTFERVRSLKLNSNPITKFDISSPVPTLKMLNLSNAQLASIDGSFNNMPNLERLVLDRNYFVSLPNTIGNLRKLEHFSIANNSVGELPPEIGCMNELRILDAPGEPQNPNAFTNNKGANGLLSAGSSTEELLMPDGSRRPSQASSTLLSVGPSPVPGGGDRKSSVVSVYGKGGRKTSVVSRSTTGASSNTTVAPSMASRKDSGLSARLTNTFAGSLRNLYLADNQLDDDVFDQITLLGELRVLNLSYNDLSDMPQRTVKSWPQLVELYLSGNDMTSLPADDLEEYSLLQTLHLNGNKFTNLPADFSRAKKLAVLDCGNNSLKYNISNVPYDWNWNLNPNLRYLNLSGNKRLEIKQTGFGTGLQNREQYTDFSRLQNLRVLGLMDVTLTQPSIPDQSEDRRVRTSGSLAGHLPYGMADTLGRNEHLSTIDLVVPRFNSSDSETLLGLFDGQALSSGGSKIAKYLHENFGHIFATELKALKTRQNETPSDALRRAFLALNKDLVTIAYQHTEERPSTAHRGSAAPLVLSKEDLNSGGVATVVYLQAQELYVANVGDAQAMAIQSDGSHRILTRKHDPAEPAERQRIRDAGGWVSRQGRLNDLLEVSRAFGYVDLMPAVQAAPHVAKMNITPQDEMVLIATKELWEYLTPGLIVDVARSERGDLMRASQKLRDLAMAYGSNGKIMVMMISVSDLKRRQERSARLHRGQSMSLYPSGIPDDFQYPAKRGKRTKGEVQDSTLHRLEAEVPAPTGKPSIVFTDIKNSTNLWEMYPSAMRSAIKLHNEVMRRQLRRIGGYEVKTEGDAFMVSFPTATSALLWCFSIQTQLLEVNWPSEILNSVSCQEVFDNDKNPIFKGLSVRMGIHYGEPVAEIDPVTRRMDYFGPMVNKASRISSVADGGQITVSADFISEIQRCLETYQEKGNGASGTEDAFDDDAVAAQIRRELKSLSSQGFEVKEMGEKKLKGLENPEYIYSLYPHSLAGRIEYHNQDVRAAEAPALKPATLEAGSELGFDPEMIWSLWKVSLRLEMLCSTLEEVSGRGLQPPETELLERMKQRGGEVTERFLFNFMEHQVSRIETCVTTLSVRHIAAGGGTITKLDDLRTPMPEVLDDLAKQLKLLEMYKARYGPLSDMEDEGIDTEEEMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4P5</accession>
    <name>A0ABR1X4P5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005337</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673270.1">
        <property type="nucleotide sequence ID" value="XM_066809652.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042712"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="12"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8090376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="437" mass="48359" checksum="1DC8C07EF4791247" modified="2025-10-08" version="1">MSTQTQAKKSFEIAVIGGGIAGATLAVALIKHGIPCQIYEQGHGFSEIGAGVAFSPNALRAMDICDKSLRAAFEKVGTHNQWPEKHDVYFDVLDGMAGGDTPATNKQLFTLTNEQGMDAVHRAHFMDEVANVIPKEKCHFRKHLDRVEENGGKDGRVKMFFHDGTTAEADAVVGCDGIKSRTRQLVLGDDEHPSAHPQYTHVYGYRGVIPMEQAVEALGEERAKNSCLWIGKGAHILSYPVDGGKTFNMFGAVVDKGDWPSHDQLTLPTTREEALHHYADFGPMVKKQFELVEDNIDKWALFDTGDHPVPKFNKGRIVLCGDAAHATTPHHGAGAGFCVEDSAVLSELLTDSQVTKPDQLAAVFEAFDAVRRPRGHWLVQSSRRMVELYQGRAKDVDSNDVDAMRKEMEERFSTVWGYDLKKAIQEGKENMHKRFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4Q5</accession>
    <name>A0ABR1X4Q5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673228.1">
        <property type="nucleotide sequence ID" value="XM_066809610.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042670"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="242" mass="27585" checksum="0F62E51DBAB6B965" modified="2025-10-08" version="1">MKTTVELWFARDSPDRDRRSALSLAELPRMTIRDPGGTCQRPSQDANERNDPKGHRGIARVELKGCCYTHPLETRGGRLIVRTSTSGRRDRILQRFYATRQVLEAWKGGCWRRGMEFRLGKSRSTSRYCCRGWIPHDKLLGLAWLRIRIWDVVLGRNEQTLVSSGSFFKLNWTSGDRSDISSSRPDELTDFPASCAACKAEELQDLLPGTLPLDHAMQSAFCLADTEDRRELPFFYSKPAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X882</accession>
    <name>A0ABR1X882_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mesaconyl-C4 CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673607.1">
        <property type="nucleotide sequence ID" value="XM_066806311.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039371"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052741">
        <property type="entry name" value="Mitochondrial_HTD2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152:SF2">
        <property type="entry name" value="N-TERMINAL OF MAOC-LIKE DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="39955" checksum="EC1BD57EEC6B9A30" modified="2025-10-08" version="1">MSISARTPGWSTQRFILLLSRTTPLPRVRCWPIQLQRQRRQLATSARDAADQMAHTFADRTMTRRQVLDGNQLQKLSLTLGRPQLHPGFDVSESPPPDGTPLPPGYHLVYFTPSSLETELGPDGTDRTFNAPAPFTRRMWAGGRMTWKPPPAPQLRVGQRAEERTRLLSATPKKSRDGGEMVLVEVEKEFWGPEGLALVDRRSWVFRPEVPAAHAEASRAVQDTTVWGPSTAEDVDTGDGSYPYRQMRWSPVGLFRFSALTFNGHKIHYDGSWTRSVENHPGCVVHGPLNLISMLDYWRDVCGEGPVGGISYRAMSPLYAGDTYRISAQKPVQSDDGKSWEVLVQNGDLVCMKGTITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8X4</accession>
    <name>A0ABR1X8X4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ophiobolin F synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673878.1">
        <property type="nucleotide sequence ID" value="XM_066806582.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039642"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00867">
        <property type="entry name" value="Trans_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF72">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G01210)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="364"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8091906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="573" mass="64229" checksum="A86BA6C7E33AAB07" modified="2025-10-08" version="1">MEPLSYQSKLVPADEASRTGCFTTLPIRIHPRDDLADTASHRFVRDWAREIGDGREKKTHFSFSPVGNWSSLIYPEAIPERLGVLAYLSDLGLIHDGKSAPTLLPLICVFVDSFVPDKGEGLSIEEAKAENDELHAALDPDDGRCLTPDSRAMKTKKLVSQCILECVNLDHERGLNMLAAFRDVWLAISEKNSDKEAQTIEEYLQYRSENGGMLVFWPMLQFSLAISLSEADRKLAQPMIDAATEGLLLANDYFSWERECRELESGHSQRIVSAVELFIRTEGLSPEAAKDEVKRRIIKSESDFCQRRDELYRAQPGTPEKLRRWIDCAGLAVSGNHYWCSACPRQNAWKNETLTNGTNTMNISHGTNGVHGGNGTNGNGPKRALSPITEDDIPTKKRRNSYDVSSYPLLHIQHALQRRPRRPHRRPQHLAPRPPAAIQRITSVVNTLHNASLILDDLQDNSPLRRGLPAAHVIFGPAQSINSATFMFVRAVGQVAHGLSPAALTAVLEELEGLYLGQSWDLYWKHNLVCPSEAEYVNMVDHKTGGMFRMLLRMLQAESGTTTGRRLHKLHHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9J5</accession>
    <name>A0ABR1X9J5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein RER1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002477</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the RER1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674088.1">
        <property type="nucleotide sequence ID" value="XM_066806792.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039852"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004932">
        <property type="entry name" value="Rer1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743:SF0">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03248">
        <property type="entry name" value="Rer1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016013">
        <property type="entry name" value="AtER_Rer1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8092116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="173" mass="20055" checksum="E96E9120264BEAD1" modified="2025-10-08" version="1">MHYQALLDKSTPYVTYRWVGTATFLLMFFLRIFVAQGWYIVAYALGIYLLNLFLAFLQPKFDPSAEAMDSGMDMEDGSAGGLPTKQDEEFRPFIRRLPEFKFWYAATSAIGIGFMCSWFEVFNVPVFWPVLVMYWIILFVLTMRKQIQHMIKYKYVPFSFGKAKYGGGKASTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA37</accession>
    <name>A0ABR1XA37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674267.1">
        <property type="nucleotide sequence ID" value="XM_066804494.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037554"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="365" mass="39019" checksum="9EDEAC29BD5EF7CD" modified="2025-10-08" version="1">MSSLTVHLFPLISVLGLYAVSSYMTYSGLAAAFAESQANPMRLLPDGHTPLLTSYTGLAPLDSYLANLQYIFVPVVDGASAELSLLGWHWGSLLLPLFTVMLGEGLRTGRSRDLVFFELWGLAIQYCGYFVTMPIYCYVYLLSSSSQSRSTTVSATAARMIPISTLVGYVFPTVVMSLSSLHSGQSRQVAVAFWQNFPVWVATIQWALMWGSSSMPTADDAPSKAASHSTNMAFGNVLSRIYRAVALISGLMHVAGLVPIVLATFFPEHLIALSPMHLDSSTLQSLQGGNFFLPPKWDSRAQITGMAEGGGELSQSARGKNASNGKKPLSGRGGWLAGTGLAQGLMIALTTLVLGPGYTIASLMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAN5</accession>
    <name>A0ABR1XAN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DDB1- and CUL4-associated factor 13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">WD repeat and SOF domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_000343</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat DCAF13/WDSOF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674431.1">
        <property type="nucleotide sequence ID" value="XM_066804658.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037718"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007287">
        <property type="entry name" value="Sof1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051733">
        <property type="entry name" value="WD_repeat_DCAF13/WDSOF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851:SF0">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04158">
        <property type="entry name" value="Sof1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="62"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="283"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Sof1-like protein" evidence="11">
        <location>
            <begin position="359"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="407"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8093658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="436" mass="49213" checksum="7B223BD1FA027340" modified="2025-10-08" version="1">MKIKALSRSVEAYQPAGSKNSKMPKNLDPAIHPFERAREYTKALTAVKMQRMFAQPFLAQLGEGHVDGVYSMAKDPNSLERLASGSGDGVVKTWDLSNSYDKAERWHTTAHENIVKSVCWTRDQKLLTCGTDRKIQLYDPYNTPSESAPLSTWLGSASWNSLSHHRSRNSFAAAGGSGGVSIYDLERHTAAPEILSWPNATDTINAVAFNQVETSILGSCGSDRSIVFYDLRTSTAIAKTVLTFACNAISFNPMEGMNCAVASEDHSVYLFDMRKVDRALNILKDHVAAVMDVEFSPTGQELVTASYDRTIRLWNRDQGHSRDIYHTKRMQRCYSAMWTPDSKYILSGSDDGNIRLWRANASAREGIKSARQRQSEEYNNALVERHIPKVVKKAGEIKTEELQALKRREENERRHTKKQFDRRRSERDKVILAKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAS2</accession>
    <name>A0ABR1XAS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Kinetochore protein SPC25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_000485</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Chromosome</location>
            <location evidence="9">Centromere</location>
            <location evidence="9">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the SPC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674573.1">
        <property type="nucleotide sequence ID" value="XM_066804800.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037860"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23784">
        <property type="entry name" value="RWD_Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.50">
        <property type="entry name" value="Chromosome segregation protein Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045143">
        <property type="entry name" value="Spc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013255">
        <property type="entry name" value="Spc25_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14281:SF0">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14281">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC25-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08234">
        <property type="entry name" value="Spindle_Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="8 9" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromosome segregation protein Spc25 C-terminal" evidence="11">
        <location>
            <begin position="165"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="41"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8093800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="241" mass="28264" checksum="6454EF793A3E8BAF" modified="2025-10-08" version="1">MSAMAPSLADQLPSINFGFDDLRDRMAKFSARFDTFIEQGRKRVLEERNQFRMNVAELQEDQRMKKKDMEILQLKTTTHQQTISKEAAETREMQAAIASLTQQRDKNAAQRDNLKRQIKETQAEIDARLAAQQAHAARIEAQARFNVPELDFWISNLCLKIEGAGQTDRLKFVYTHIDDRDWEREAWFELCTSSRDYDVRHCRPKLEREKVERVLERVNETRELATLLKGMRELFVEAVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBE2</accession>
    <name>A0ABR1XBE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000668</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674756.1">
        <property type="nucleotide sequence ID" value="XM_066804983.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038043"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003727">
        <property type="entry name" value="PRK05330.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF0">
        <property type="entry name" value="OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="395" mass="45019" checksum="6894429C10E69A5F" modified="2025-10-08" version="1">MSRRGGSTFLRLRPAVAVPRLPRRFFSSSSSAKKTPSRAAHFAAVGAVTLSALAYQMAYQDPMKFEARTLADLDERLKKEEGITDNSPMRLRMEEAIRQKQKDIVFALEQIDGTRFKQDEWKRPNGGGGTSCVLQDGNVFEKAGVNISVVYGTLTKGGIAAMRQNHKNVKDVDNLDFYALGLSLVLHPHNPMAPTVHMNCRYFETMNPDGTPQAAWFGGGSDLTPSYLFDEDAVHFHRTLKEACDKHDKEYYPRYKAWCDDYFNNKHRGERRGIGGIFFDDLDEDVVDTQNGFAFVRSVLDSFLPSYLPILEKRKDAPFTAKEKEWQQIRRGRYVEFNLVHDRGTAFGLNTPGSRVESILISLPRTAQWAYMHEPEPKSRESRLLEVLREPKEWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBJ4</accession>
    <name>A0ABR1XBJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674789.1">
        <property type="nucleotide sequence ID" value="XM_066805016.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038076"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="299" mass="34323" checksum="02F45D7E67C3C89F" modified="2025-10-08" version="1">MGSQGRPKLFDFECLVGFFIQPSMKQEPNYALTTHADLGLIPRSYVTEAGATEDSHLSPWQRFANHVEQLNRNAKNGEQYKVLYVGRHGQGFHNVMEAKVGTPAWESHWALLDGDGDAVWADSELTDQGKREAADNGKIWRRLIEQEKMPWPALYCSPMRRCLETARLSFEDLAASQGKPYQPMVKENLRERMGRHTCDRRSSKSWIQEHYPSYLIEPGFTEDDELFEADRRETDEEHILRARIAMEEIFENEPNQFVSITMHSLASRILMRVIGQEPFRMSPGSTTAFLVKATRSLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBQ4</accession>
    <name>A0ABR1XBQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phospholipid-translocating ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000703</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674791.1">
        <property type="nucleotide sequence ID" value="XM_066805018.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038078"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF9">
        <property type="entry name" value="SPHINGOID LONG-CHAIN BASE TRANSPORTER RSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="269" mass="29434" checksum="B68C66A181793ABD" modified="2025-10-08" version="1">MADALPLGLYLPPGVKPFGPGNNCNLDICPIEFTVYGYRPSLAANITFLSLYFISAAIHLYLGTRWKTRFFMICMLAGACNAIIGYAARIALYYNPFNFTAFMIQIICITSGPAYYSAAIYVTLADAVTPSAAPLFLGLHQLRCGLSPLPGAGGALSTVSAASLGSEQLSKAGVDMALTGLSMQVIVMVVFCGLFADYLIRYFRAGRTDRFGRRAQLFFSFMALAILLILARCAYRLFELRDGYESESIRNESYFIALEGGVWLMNPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCL1</accession>
    <name>A0ABR1XCL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein- variant</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675195.1">
        <property type="nucleotide sequence ID" value="XM_066805422.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038482"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF15">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="466" mass="51797" checksum="C6AACE8172398739" modified="2025-10-08" version="1">MTSSLQPRSAARRGPQKWDRSIPPSLRPLVRAYALGYASVVVPRLFTLVLQQVTTTAKSRSGGGPDNGALQPPRESAVVSLQRILRTGLDPQRFPAFCATLVGGTTFTAAWFSLKLLQSKASRGFTETVSAENGDESNITPTTISYAGRTLDLSLFAFCRAFDVIVGELWAQRRTRRLANQQWTNFETAVSRLADPSMFAVSCALIMWSWFYYPSRLPQAYNKWISSAASVDKRLIEALQRCRTKELRYGEDTGQAPLIQGMCREYKWPLQWGDPAVAVPFPCEVVHMGCGPSCEYHALSRFCRSFQWSMFTYLPLNLLLVARKPSFHKLKHALLSAARSSAFLGAFITFFYYGVCLARTRIGPHILGKDAEARNRIDGGLCVGTGCFACGWSILLENPGRRKDMALFVAPRALATLLPRLYPLDKQWRETLVFAASTAVVFTCVLENPTRVRGVLGSVLNTVLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD01</accession>
    <name>A0ABR1XD01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675314.1">
        <property type="nucleotide sequence ID" value="XM_066805541.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038601"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="292" mass="33520" checksum="8A4CCD5DD5C7B25F" modified="2025-10-08" version="1">MSSTGPNPQEIFAFLAQIPTHDDERFQNWGQNWAQASPFDVASASSVDLTPIHFRLLAPSVRAPTYGGSTGSASTRSASTASTAQNSMWSRRSSKSGKSSKSYNTTLSSPPRSTASTVPSVYNNHATIDPPHNPRYFWEWHVGTEHLQDNLPPHCICWFCDQEFSARNHNGNERENFRFRLEHIRDHIIQGRLTAQDMRPDYFLLEHMYRNGLLEKVHYQLECSYTEGPTASGIVEYNYTPPERRRAKELESRVYHDNDKEERRRRRRQGQQRPMPRVPPHSAGRMEYGVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD28</accession>
    <name>A0ABR1XD28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675342.1">
        <property type="nucleotide sequence ID" value="XM_066805569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038629"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037473">
        <property type="entry name" value="Lcp-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37539:SF1">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37539">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic" evidence="2">
        <location>
            <begin position="142"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="476" mass="52911" checksum="7D12C15ACD004E22" modified="2025-10-08" version="1">MGIFTRDPSVRTVYGHTFKWTSEHTPVEDLHPLVYTYDKVGADALDSLDEIVPPVALSFTRKDIEEAYEPKKTEPQEKRHRDLFKLVKEHGNSDEKLRKLWTEVNTVPDWVDWDQIERGQNVFWRYGGPSVTTAAGRNPHPHRGFGANVVNRRLLETTQHTLGVHDGLGAIQPGGHGWESSVRVRLLHASVRKRIVQLAREQPGYYDVAAHGVPVNDLDCIGTINTFSATLLWLGLPRQGIRPRAQEIVDYLALWRWVAYVMGTPHDWLADPGKAKAMMESLLVSEIAPSPKSGVLANNIITGFEGLGPAYASRGFMEAEAYWLNGSQLAGELNIHRPSVYHTALIVGQCLFFMISGYLCRCIPALDSRHIKLARHGLYELLVHNKSKGGLGYTSKFAFKWIPDLVNVETPQGAPIPGRPKTSGALRHAGVERTALLTLLFVGALLGSVAWLGVRAVAGTDVLARGLEYVRRISYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XED3</accession>
    <name>A0ABR1XED3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675695.1">
        <property type="nucleotide sequence ID" value="XM_066805922.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038982"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="104" mass="10063" checksum="498B3AA62353A747" modified="2025-10-08" version="1">MSTGGPPAGIHIGGNKGDRGLVSKLKDAIKPGSSSAKKDSTSLPGGAAHESQDRGGGGVLNALKPGTDNMEGRSSMPADARGFQPGIPGGPGMQGVGPSNSTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQA0</accession>
    <name>A0ABR1UQA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptide hydrolase</fullName>
            <ecNumber evidence="9">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_015315</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M28 family. M28A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660514.1">
        <property type="nucleotide sequence ID" value="XM_066819629.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052689"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03876">
        <property type="entry name" value="M28_SGAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02130">
        <property type="entry name" value="PA_ScAPY_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041756">
        <property type="entry name" value="M28_SGAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF17">
        <property type="entry name" value="AMINOPEPTIDASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8 9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044968467" description="Peptide hydrolase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="10">
        <location>
            <begin position="151"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="11">
        <location>
            <begin position="263"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8061094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="510" mass="55112" checksum="14A9D5B08B2C42C0" modified="2025-10-08" version="1">MVGFTRNLACSAALLSTASAYGIQQPMSSDDSPIAAGHSSKRPLVSSKALQDSIKGEHLLRRAKNLYEIAKLGEEEYNHPTRVIGSDGHLGTLAYIYSTIAKFGDYYNLSYQAFPAVTGRVSEFRLVIGDEVPKSAEPMSLTPPTKHKEPVHGNLVLVPNQGCDAADYPALLEGNIALVMRGKCSFGTKSEFAGRAGAVAAIVYNNEEGEVHGTLGTPSDNHVATFGISDAEAAPVIKKLEKGDKVDAIAYIDAEVKTTLTDNIVAQTTEGDPNNCVMLGGHSDSVTAGPGINDDGSGSMTLLEIATQLTKFSVNNCVRFAWWAAEEEGLLGSDYYASTLSDEENQKIRLFMDYDMLGSPNFAYQIYNATNEANPTGSQELRDLYVDWYESQGLNYSFIPFDGRSDYDGFIRAGIPAGGIATGAEGVKTKEEEKMYGGKAGDWYDPCYHQLCDDVGNVNMTAWELNSKLVAHSVATYAVSFKGFPERTAVAAATEDYEGKTKYHGKKLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQA4</accession>
    <name>A0ABR1UQA4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sm-like ribonucleoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660508.1">
        <property type="nucleotide sequence ID" value="XM_066819623.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052683"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040002">
        <property type="entry name" value="Sm-like_LSM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13110">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="2">
        <location>
            <begin position="28"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8061088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="83" mass="9059" checksum="0A627DE916BD63A7" modified="2025-10-08" version="1">MADVEDSAAAGSVAEPPRSRAPSPRRGRAYDSHMNLVLGDVLETIYVVDDDENDEEIRTVTKKSEMLFVRGDSVVLVSPHNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQH1</accession>
    <name>A0ABR1UQH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660588.1">
        <property type="nucleotide sequence ID" value="XM_066819703.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052763"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="120" mass="12943" checksum="91DDAA75A2D478C3" modified="2025-10-08" version="1">MPVTPVHYETSQFMDTVVAGLAAIGLTKGWVIFLQIVLVLIFATLAIFLIAGCSAAWAQDRKDGLLDSRLKQLTTKTKELETLQSSIPDIEKGLDRVLGKAKYVTAGQQSGAASFITCVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQP6</accession>
    <name>A0ABR1UQP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Trichothecene 3-O-acetyltransferase-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660647.1">
        <property type="nucleotide sequence ID" value="XM_066819762.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052822"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054710">
        <property type="entry name" value="Tri101-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF310">
        <property type="entry name" value="FATTY ALCOHOL:CAFFEOYL-COA ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22664">
        <property type="entry name" value="TRI-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Trichothecene 3-O-acetyltransferase-like N-terminal" evidence="2">
        <location>
            <begin position="28"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8061227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="463" mass="52035" checksum="7E2BF4107671F06D" modified="2025-10-08" version="1">MSSPDVYSHNDLLGTEHMGPKGWIRQFYCFELPENYDVENVTSLVKNAYAAMKARCPPAGYKMVPVMDGSAQPGRFEWRRFPEGEIEDFKVKDHREDFMTFADFKAKEYPMAPLLPEKFCPRGLWVDENDLALWFHTTWMQANFVKGGLILCMGIFHSAADQTAAYIMTKVLAEEMAKAQGLPVADPVDVAVLLKDREKLHKSQRAHLAQQAVAQQGICEEHPEYIILPFTPDAPPPKLLAPISQSHIFHFSPAALEQLKRDCQPTPEQLQTLKGDKDLPAFVSTNDALNALLWKIIMERRRAGLHKHTLGNLLAWAPVFCDLKSVVRESSLADLAVLCRRSVAQRTDDPDVVHKLEAMLEGVENLDRLAPQVFLDMPGRNMITSNWRDNTYYDLDFGAALGGKMKAMRAPSVGVCHGFHIVLPDRPDKPGIEVIVSVENSAIGALLKHPVWTKYAEEPKQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT41</accession>
    <name>A0ABR1UT41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="3 8">4.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_014192</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>orotidine 5'-phosphate + H(+) = UMP + CO2</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the OMP decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="3 8"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660694.1">
        <property type="nucleotide sequence ID" value="XM_066818506.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051566"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04725">
        <property type="entry name" value="OMP_decarboxylase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119:SF2">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="9">
        <location>
            <begin position="36"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8062095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="279" mass="30323" checksum="F87223ABC3F1DCC7" modified="2025-10-08" version="1">MSATRQPQLSYHERSLHHPHPVAKRLFEVAEQKKTNLVISADFTNTEELLACADKLGPYIAVFKTHIDMIADFSDETVTGLKYLAEMHDFLIFEDRKLVDIGNTVQKQYHGGALRLAEWADLVNLSILSGDGIVEALDQTITAPDFPYKGERALLLLAEMTTKGSRAVGAYTEQCVELATAYPNSVIGFVATRALTPPATGSGDMVVFSTGINMSAEGDTLGQQYQTPQSAIERGSEFVIAGRGIYAADDPVAAAKAYRASGWEAYVQRTRQGDKSSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUD5</accession>
    <name>A0ABR1UUD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661134.1">
        <property type="nucleotide sequence ID" value="XM_066818946.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052006"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045125487" evidence="1">
        <location>
            <begin position="21"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="76" mass="7728" checksum="EF9345560E3BC568" modified="2025-10-08" version="1">MLFDASAVAVLASLAVLASAMPVFVGNNEGINGIVKRVPCPASKSTEAASADYKRGIEDEDALGDDTPGAIIACNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUN7</accession>
    <name>A0ABR1UUN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661238.1">
        <property type="nucleotide sequence ID" value="XM_066819050.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052110"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="100" mass="11050" checksum="465B90769D338DE3" modified="2025-10-08" version="1">MCRKVKTKSVCATCNDRIGENTNTQWCRDARRRGTLGRCTSGLRRAEEEFRGEECKMSDFAAKGLGWRRTGGGGSGGGRGRVMDNDNDGDSDDYGSPYTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVD5</accession>
    <name>A0ABR1UVD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014957</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661459.1">
        <property type="nucleotide sequence ID" value="XM_066819271.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052331"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="5">
        <location>
            <begin position="80"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="4">
        <location>
            <begin position="365"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="643"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="676"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="716"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="749"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="777"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="810"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="874"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="911"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="940"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1008"/>
            <end position="1040"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1152" mass="128956" checksum="D17EAC4BCE51AF33" modified="2025-10-08" version="1">MPNRQENCAGVITADGHARVQIGDSHNHTVVNNYLNSNPKLADSYDGDTDDEQVRTAFLLRLNTSPYEDRKNRKPNRVEGTCEWFTTHDLFRSWQEEKSAMLWVSADPGCGKSVLAKYLVDEVMASGTTRTTCFFFFKDDFDDQKTLEGALCCILHQLFVQKPDLLLHKFLDSFDEEGEQLFSSFDELWRMLIEATGHHNQGEIICILDALDECVENKRLAAALTQFYNNDKMVSPLKFLVTSRPYLYIGRELKALEDSQPTIHLSGESPEEVDKISQEINLVIGQRIKELGEMLRLPMEELQGLHAEITAINHRTYLWVHLTFSTLEETVFLSRAELRAKIHELPHTVEEAYDGILRKTCDPDKARKILHIIVAADRPLSLKEMAAALAFRGESHQCHQDLERDLTSPESLHIAIREACGLFVVIQASEVFLIHQTAKEFLVCLPPVRATTCSPLKWQYSLDPEESHHLLSEICIKYLLLADFERPTTVESSRAIGDERQFSFLEYAACNWAYHFRQTRNSGANLEHLALKLCDVRSPSCLHWLGVYGEKRMDKWISLELSTSLLISSYFGLDKLVASILRNSKTDVAVKGTSYHRTALSWASEKGYLAIVDLLLKHVNRFQVFFTDWSASHTSIVNRTDRFGRTPLWFAAANGHLDIVQALLRKGAKVDVRDQHGFTALSWATQHGYSDIVALLLENGAQQKSKSSQMDSRYLDGSTPLIKAARDGDEIVLKMLLNGGAKPGTQDFNGRTALVHASERGFDSVVKLLLDRGADVDATTALLYAAAHGHDRVVKLLLDQDADVGHSDADGCTALFLASSCGHYATAKLLIDRGANIETTNKHGFTSLTAAASGGHDTVVKLLMKREARIINSEGNSALSHAAHRGHLATVRLILEQGAGIVTMDELGISLAFACDEGHADVVELFLDRGVSVNRQDRDKGRTGLSLASSNGRVAVVKLLLDRGASIQAEDNNGARALMYASVGGHIPVMEMLLDRYWWTDINAQDNDGWTALIYGAWKGRIAVVELLLDRGAGMDVRDHDGWTALILALAMLPEAPDEDVDKQHQFDRWGLRITPRPSFDYPTSKFRTLLVGYFWLSSAPRLAYPYSDRIIPPITWSNDHLRMSLEPMQQYSLLQQFVVLAILTNIVISFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVG0</accession>
    <name>A0ABR1UVG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661524.1">
        <property type="nucleotide sequence ID" value="XM_066819336.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052396"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053209">
        <property type="entry name" value="Gramillin-biosynth_MTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643:SF2">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="357"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="700"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="786" mass="86761" checksum="D6682185854C5194" modified="2025-10-08" version="1">MDIKHMTDDTPYAGHFKQLFAAAEHSASRKGESVTDHPPAEQLIASFLWKLQISSMQRAAMSSEQHLSTTQVPAPYPPCTRSLRDLKPAMISEMKLETHHRGMKTLLRVLTRPDRMNAAMAIVEDQGGTAVLLQLYHVPEVSVVPTEHILYKDRVCILKEPFFKGTTDGTYSLRVDHVNDIIWLAPDDEHVPAKWRRQQTGAPKASPEARMRGNKAVQNNNWAEAESLYSAAVNSAATLEEARLAHLNRSLANLNLGRFEDALSDAMKGGQDEKPNESEKALFREARALYRMQRYRECMQKLVVLAAEFPDNQAAKVELERAQARLREQLKGLYPFRRMYKEAQAGIPIIDCATFTGPVEVRPSPGRGRGLFTTTAVAAGDLLMCEKAFEYCYAGDDHPEGNNKTTLLMDMETRSWAVGGQAGLISQVVQKLAQNPNSSKAFLDLHRGAYQAVSADEVDDRPVVDSFLVAKTIMANAFGTPRTSRSSFRTTALVPEGKTPSTTTCGIWIQASYLNHSCAGNCRRSFIGDMQIIRATRDIPADTELFFSYKQAEPLTSFDETQKSLRNWGFRCDCALCLAKKATSDDTLKRRKALLAQLKYIMRPSTVPRAIDTKRALAVLEKVEATYATPVRASSTATGSDSVLPSSVQITPRLELWDPYFGLGAHLLNRGKKDDAVKVTIKGFEALGFVITATLPKASNGGGGGSKNKAGNVTSDSDSDGGTGQLVVESWGVVVDYVVPAFLTLFRVYRATSPELANRAREYAATAYSMLVGEKETIYDEIPELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVN3</accession>
    <name>A0ABR1UVN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">glucan endo-1,6-beta-glucosidase</fullName>
            <ecNumber evidence="13">3.2.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Beta-1,6-glucanase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Endo-1,6-beta-D-glucanase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Endo-1,6-beta-glucanase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PG997_015093</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Random hydrolysis of (1-&gt;6)-linkages in (1-&gt;6)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.75"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.75" evidence="13"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661595.1">
        <property type="nucleotide sequence ID" value="XM_066819407.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052467"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF39">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 17" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 17 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 18" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046381074" description="glucan endo-1,6-beta-glucosidase" evidence="18">
        <location>
            <begin position="18"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="19">
        <location>
            <begin position="119"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00036633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00041472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00042025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00043257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK8062996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="432" mass="48419" checksum="79A1E3954726AD2F" modified="2025-10-08" version="1">MLRVTIASILLACVVDAWLPQDRSDLAAFNQSRYVGELGSGSSPISQTALPKSEASTLVIRSLFMYASTNLPDIGWLVSEPWMMRDEWRSMGCTLDSDVSEFDCMRNHYTGNNRAAGNQAFQKHWREWINADTVQSVHDVGLNTIRIPIGYWSYNDIVDKASEPFADGNAMLPFLDAVVQKATNLGMYVIIDLHGAPGGQQQDVFTGQNPNPCRWLSWMTKRIHSNPAYASVGMIEVLNEPVSKHDAGGRYPAPGEDPGLVEKYYPRALKAVRDAESGVPDDKNLHVQFMSAKWDAGNPRQSSSVANGFATAFDDHNYIGFALQNTGDQYRLMHLACTDSRLVGGEDFRITGEWSMTSGADWHDAAFFKKFFTAQQQLYEKPGMNGWVFWTWKTELNDPRWTYSYGTYLNYIPTTAAGLENNVYQDVCAGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVS2</accession>
    <name>A0ABR1UVS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_015126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661628.1">
        <property type="nucleotide sequence ID" value="XM_066819440.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052500"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8063029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="74" mass="8212" checksum="D37BC120DCA7BF74" modified="2025-10-08" version="1">MYFFDEFVNATNPKAGCGSLRCSPSPIESHLGNPGMLQGLGLPALWRVGDDLFSERLTQLLNTFWIVSIALKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWE9</accession>
    <name>A0ABR1UWE9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Adaptor complexes medium subunit family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_014472</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660974.1">
        <property type="nucleotide sequence ID" value="XM_066818786.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051846"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09251">
        <property type="entry name" value="AP-2_Mu2_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14836">
        <property type="entry name" value="AP2_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043532">
        <property type="entry name" value="AP2_Mu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043512">
        <property type="entry name" value="Mu2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0168">Coated pit</keyword>
    <keyword evidence="2" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="8">
        <location>
            <begin position="168"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8062375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="436" mass="49101" checksum="27A849738B1025E8" modified="2025-10-08" version="1">MLSGILIFNQKGENLIFRAFRNDCRPRLADVFRIQVISNPQVRSPILTLGSTTFSHVKHENIYLVAITKSNANAALVFEFLYRLIQLGRGYFGKFDEEAVKNNFVLVYELLDEIIDFGYPQNTETDTLKMYITTEGVKSERAPEDSAKITMQATGALSWRKADVKYRKNEAFVDVIEDVNLLMSATGTVLRADVTGQIIMRAYLSGTPECKFGLNDRLLLDHDGLQSLPSGNRLGTKATKAAAGSVTLEDCQFHQCVKLGKFDTDRIISFVPPDGEFELMRYRATENVNLPFKVHAIVNEVGKTKVEFSIGVKANFGSKLFATNVVVKIPTPLNTARITERCTQGKAKYEPSENNIVWKIGRFTGQSEYVLSAEAELTSMTNQKAWSRPPLSMNFSLLMFTSSGLLVRYLKVFEKSNYSSVKWVRYMTRAGSYEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWL5</accession>
    <name>A0ABR1UWL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660807.1">
        <property type="nucleotide sequence ID" value="XM_066818619.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051679"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="224" mass="25481" checksum="ED205B71CF6A3E18" modified="2025-10-08" version="1">MSDTPGPRPWTNAEKKWLTQCLTTADLEFPSNDYRFGGVRKLTALVHEFNAMFYNTPGSRSESDVKAQVDEIHKDFDDLIWILPQNIKDTRCSRLVILWILENCDPYPDEEGGGTDEGSCQCHYDEGASDLLLKWLHVELQRLICRVEERLAKFRYQDPLKSMDPIYLLELESVWRTRDSQQEVEDEVGVPGDEADDNETATGVTDSGSEDNTIESGVQDGSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXK8</accession>
    <name>A0ABR1UXK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014878</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661380.1">
        <property type="nucleotide sequence ID" value="XM_066819192.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052252"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="10585" checksum="9A05D9C52B27A493" modified="2025-10-08" version="1">MQNSLRLLSQRTKVRCKEYHYEWYPRELLMENVAGLVIECDAAHKMDKAELLLKKEDKLAQEGPKPDKNWGVVTEPKPDRLLYTSIPSNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYP4</accession>
    <name>A0ABR1UYP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661497.1">
        <property type="nucleotide sequence ID" value="XM_066819309.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052369"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="140" mass="15557" checksum="1B15386723A227B2" modified="2025-10-08" version="1">MEVGQEFEPAPARRADEEGVEGLHNVRVDATEDREPHERDVQFELNFLNAREVSAPDVAQKVVKRLVVRPVSVDVLISDPALGNRHRGWMVQIVVLEHQEHLDFHSLELAEDLLWVFGGASGVAVDTEGVQVVVDAGSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYR6</accession>
    <name>A0ABR1UYR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661527.1">
        <property type="nucleotide sequence ID" value="XM_066819339.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052399"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="31"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="110" mass="12083" checksum="604F712E930BB5BA" modified="2025-10-08" version="1">MLHRAIVGGQVQGATWLTTKANLDPRYRGFGQSALPQTLWDALVIAEKLGLRYMWIDALCIVQDDEEDWELEGSRMASIYSSALVTIAAASSSSSHDGIFNKRSITPLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2K3</accession>
    <name>A0ABR1V2K3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_012164</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662170.1">
        <property type="nucleotide sequence ID" value="XM_066816478.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049538"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="9">
        <location>
            <begin position="140"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric reductase NAD binding" evidence="10">
        <location>
            <begin position="384"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8065417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="61848" checksum="2082B7F6C130565F" modified="2025-10-08" version="1">MGWSYSFAEISDAEKHARRLALDSYGLYAQLSTLLPIAVALVVRLAVWFSRRETTQKIAYDAVPTSPGAKYIRESTTTGSVGRVFRRISWYLGDDIYIAGKNWGRRDQFIFGGLWTVWLVFLCFMGTGNDYNHLTKRFAAIGCSQFPVQYLLSLKYLNPVAYAFRSSHEEINRWHRTLGRIVYFLLAAHAVLYSNKFVQMGIVLKMSTNTTVILGLVGIISMTLPEHNGIGCVAMTLPIVIFFHVHHARLYMIESLVVIVVDIGVRKFYTVTAQAALQSIPGTDLVKITATVSPEMAAQFKDSPGAHAYVNVPPSSRPSANPVSPSNLVFEYIYSPFTVAGVSEDSWELTLTRRHGQGKYEIFVGHRRAVWRCEVLPQFIGVKFDRVLLFAGGVGATFTLPIYHYLSREHPLTRTEMIWAVRQPGEATWPTSELEKSILDDDHVHLYLTGNDFGPDGNGHGDSSSGADEEIELDQMHADHRRAKHAAVSNHRRPDLKKIVDDAFRQGVEDRVAVLVCGPDAMARELREYVGVWAKKGRYVWWHNEGFTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3Z0</accession>
    <name>A0ABR1V3Z0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662664.1">
        <property type="nucleotide sequence ID" value="XM_066816972.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050032"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF103">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="273" mass="28855" checksum="1B44D4A36FC93E98" modified="2025-10-08" version="1">MQKMSLMGKLVIASHPIPGRNADSSDLVASSGARGLGNYMARACAEAGAKTLVIFDANQELGDASAAELHSKTGLEVIFYKVDVRQDKAINAAVDAVTERYGAPDVLINSAGIADSNIKAEDYDPAMFRRLIDINLTGSFQMAQAVGKAMKKANKPGSIVLVASMSGSIVNYPQEQSCYNASKAGVIQLGKSLAAEWAKYGIRVNCISPGYMDTALNRVPALEAQKKIWCSLTPQNRLGAVDDLNGLAVFLGSDASAFMTGSNVIIDGGYTCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3Z7</accession>
    <name>A0ABR1V3Z7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vegetatible incompatibility protein HET-E-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661754.1">
        <property type="nucleotide sequence ID" value="XM_066816062.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049122"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37948:SF1">
        <property type="entry name" value="BLL5189 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37948">
        <property type="entry name" value="ZGC:113208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="37750" checksum="11062F57486CB55D" modified="2025-10-08" version="1">MDGYEARRLANIKRNAELVHDLGLEDNNTKPARETKTPTTSTTKRRKLHPAPPTRTSRRLASAPSRPTTYNEEALQKALVEPESDTRRSRSRTKKGAATSRAKIKAEPSPSPPSTTATPHPDLDTIIAGWTSWTPTAPPPTRDEVTGEYHFESHPNFRPNKSPASILREGAFGGTYWRPLYSKRLCITVAEDWRELPAEWLSGPEGNINVDRQLTSTEYDPSVNKYGVRCGQSIEEWEAAGWIAHEYDVRGWFQWYCRFWMGRRCEGEDERQISRWKKCVGETGRWRRILLKKYVQMGVRSVFDEGDEEDEERGRSVLSCTRLVITGLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4X0</accession>
    <name>A0ABR1V4X0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012989</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662995.1">
        <property type="nucleotide sequence ID" value="XM_066817303.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050363"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF13">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="32017" checksum="4F822D846E97F2F9" modified="2025-10-08" version="1">MPVATAQEEQEKPLTGQYDNEYDSEEEESQARRRRKQTSWRENLGCNLCILAVVSIVSAVLGAMLASRNVDLDSKCSAYTSQYSPVLKDVKIKYDMVSFNGSFKAQTIYRQNASPEVDAAWEALGLDSRAGVIPLSEGPASGLTPHHVQVSPEHGGGYFVNVEGLHHLHCLNLLRKGLWYNYEYYRALGLHAFKNEEPILQLHVSHCLDTLRQVLMCNVDTGVLGQVWYDHPEGPQAFPDFQSRHKCKNFDAVRDWAVALQAPPVEELPEDFMKAPVDGDVIPGDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V560</accession>
    <name>A0ABR1V560_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Spindle-body formation-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663093.1">
        <property type="nucleotide sequence ID" value="XM_066817401.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050461"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021589">
        <property type="entry name" value="Cut12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11500">
        <property type="entry name" value="Cut12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spindle pole body-associated protein cut12" evidence="2">
        <location>
            <begin position="49"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="281" mass="32502" checksum="07C9124A86BC849F" modified="2025-10-08" version="1">MRSQTRRVYSQNLQTTGLNHPQITPETYWHPYDSRNRHLTPEASLVWSRDPAKTERCSRAVTYETPAPKKDDDMSEEDWEDDDGADVTIDLNEPKSNSGRYWKSQFNKYHADAREEMSKLVKHKHLSRMYAQQKDIENTELQERVKELERQVRLKDDEIKQAQKRPALTRTTSVASASSRERQDSENWVAERARQSAEREVARLEREVATLKKENADLRRENEIIKANASDSAQTHAQAQAQAYSQAQVYRTTSAMTSERAAAAKARVAQKRRERAALRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5H8</accession>
    <name>A0ABR1V5H8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C6 finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663201.1">
        <property type="nucleotide sequence ID" value="XM_066817509.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050569"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="540"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="119"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="364"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="364"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="504"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="549"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="625" mass="66887" checksum="D1A398F4FB6FD7C4" modified="2025-10-08" version="1">MASASPVESYSGYSAARLSNGSESPVRPVEPKHVAFELLFPESPQYRARLPLRVQIFPHDSTESIVTTVKNFYGLYSGPNGSKGVSFEDDRGNTLIARYENFRNHMVVYVRVIEGSPPASGPYPASSYPPAPMGTPAYSQGDYAPQSAQQAIGQHISRPASRTSRMRSPSPNGGRGRRSTSGRSRSSKNRGPNYDNHSDSMNGYSSGDNGASSVTSKVKEQIGNTDISVENIVEGGRRKRAKFESSELPLFAPPQMPAATSNPSVSPARRVEHQRPALPFAHPGQNPFTNPRPLQSPQSYNTGYNHVGAFATPVTEPRRHRGSIGYPAVPGILPTPDPTVGSCMSEEDKDVAIQLMRLGEMSNISHGRTSASTLDDTFSGKADAASSTGATSDSESGSDGEQHAARRQKLDLSGASRKMYQTTESHFIPHRDSAAASGDDADYEDGAEEGSAGIKSGPNKKSQNAGKPRLPALKANKPKMNKVSKSSNGTKVKKSTILPPSGPMSPTSLPAQSRKPSITTPLVPGQPGEDDQPDLSTKPRCQRCRKSKKGCDRQRPCGRCRDAGLSADQCVSEDEGNGRKGRYGRHMGVPLKNTEASGQPPLLPAALIGMPAPVSQADKNKKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5J3</accession>
    <name>A0ABR1V5J3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Superoxide dismutase</fullName>
            <ecNumber evidence="12">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_013208</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="12"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663214.1">
        <property type="nucleotide sequence ID" value="XM_066817522.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050582"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050265">
        <property type="entry name" value="Fe/Mn_Superoxide_Dismutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404:SF29">
        <property type="entry name" value="SUPEROXIDE DISMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404">
        <property type="entry name" value="SUPEROXIDE DISMUTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="13">
        <location>
            <begin position="5"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="14">
        <location>
            <begin position="100"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8066461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="216" mass="23635" checksum="FCC142EEF56CA9EA" modified="2025-10-08" version="1">MAGPYTLPKLPYAYDALEPSISKEIMELHHSKHHQAYVTNLNKALEASAAAQAEGRLHDSAAQLSAIRFNGGGHINHSLFWENLTPASSPDARPEAAAPQLLAAIGATWGSLEKFQAAFGAALLGIQGSGWGWLVREAATGQLRIVTLADQEAVVVGDTPILGVDMWEHAYYLLYKNDKATYIKNIWQVINWKAGETRFRGPREDAFKVLKTQADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6N5</accession>
    <name>A0ABR1V6N5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663617.1">
        <property type="nucleotide sequence ID" value="XM_066817925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050985"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="161" mass="18140" checksum="3BDF37C3067F53A7" modified="2025-10-08" version="1">MNNRLRRSTTLRAVDEALAAEEASRPPEPELERIETPKTGQQLKDLGFAYLGKDVVGDLTRRLLWAKFGKSIDDLTSRIGRLEYEKAGLEADLEKTRAQKRRKVDKDPNKGFVSLADIRQVQADVREGPAKEEAEKKAAEGPAIDQNRADREGDSIRVRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6Y6</accession>
    <name>A0ABR1V6Y6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mis6 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013724</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-I/CTF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663730.1">
        <property type="nucleotide sequence ID" value="XM_066818038.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051098"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22647">
        <property type="entry name" value="CTF3_NTD_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012485">
        <property type="entry name" value="CENP-I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48208">
        <property type="entry name" value="CENTROMERE PROTEIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48208:SF2">
        <property type="entry name" value="CENTROMERE PROTEIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07778">
        <property type="entry name" value="CENP-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="712" mass="76946" checksum="6E65BF67F6A4FB0F" modified="2025-10-08" version="1">MSGHDDLKGSLAEVIQGAKLKAKSRGTSIKPAVETLGSACYENGVLPDDLKELIDLVTTSAGNYLDQASLNSIIRNLYPATKVASEIVIKVVACLGHGVLKPSLAIQAALLRWIIMIHHVVDGNALSQSYPVLFNLLDTAALRSPLCQLLAMITRRRHVRPYRIQTLLSLSRQTGSDPALTGLLRVFKDYYPEIIVGEATRGKASAFKHPDLAWRERLDEIQSAHAQTSRNANAVQDAFHVARNGSGGARKGALIPEVHTSHANESSVTLEEIENADGLVKALETIEMPNQLISVLSDPLLQKLLLLRPDAESLQRANNWLVSCAQDLVSGDGDSELEGTLEIMRDYARATRNLPPVFLSLLSEVLKTWNGRGRSSMFEVLSYAPLPSTDFSGLYEAVFQRLEAKVLDGTPSSQLAVLSCYTSLLRNWAAFLLAQPQGRDSTSSAIPDLVTHVNKLALTVLQTAGAGASSNDSNSNSNSSTIATHSAVLDFYEEASRIASNPHLQRHAQIVIPPPPLVYILHFSASPATVSRLCGVLARYKAGFQAAMAGTVVSRKMSDTYSVEYINEFNGFLMDVCNCLWRSRAFNAKDANAHGCLLAAGVVEELAAYVRGFNLNVALPAMFTLSASPAFGALATAHLRDLEEVEQGLGDLDVRHAGPVTKSTLAKLARDGGVNLSWDDYRLGVLGHLEDHGMSGVAELMNCTMTTLMKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7C8</accession>
    <name>A0ABR1V7C8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metabolite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013594</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663600.1">
        <property type="nucleotide sequence ID" value="XM_066817908.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050968"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="56"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="515" mass="55220" checksum="E383801D719B26A1" modified="2025-10-08" version="1">MAAESATMAKTEAVMATPDRKKEPSPTNTLATEDIEIQPIDAPEKTYFSKTSVWLMILFSGLAIGSDGYNAAVIGNVELLLAILYPNSLTPSIYQRLSNAFLIGMIVGMLLFGIVADQLGRKTGAVATTALLVLGIILSSAANGTSEPGMFWMLIVARGVAGVGAGGEYPVSGAGAAEATDESASYRKRRGFMFAMLADLSASLGYVWGGLVPLLLLLCVGGEQNVVKYDIVWRTSFAVGLIPPLGIFWFRLRMAVSTAYRKSAMRKQKVPYRLALKRYWRPLLGCASTWFLYNWISIPFGIFSSTIISRSNAGESLVKSLGWGVVINCFYIPGPFVGGYLSDKIGRRKTMALGFTLQAVLGFVLGGAMVPIQSIFPLFVVLYGIFLTLGEVGPGSTVVLAASECFPTSIRGQMMGLISAFSKAGAAIGTQVFTATLNSYADNTTKGNQVAFLIGSGFAVLGALIALFVIPEVSRRLDDDDQAWKQYLQEHGWEANWGDNVTEDPSAVVMNRAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7P4</accession>
    <name>A0ABR1V7P4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Wings apart-like protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013925</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WAPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663931.1">
        <property type="nucleotide sequence ID" value="XM_066818239.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051299"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039874">
        <property type="entry name" value="WAPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022771">
        <property type="entry name" value="WAPL_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100:SF13">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07814">
        <property type="entry name" value="WAPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="740"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="Wings apart-like protein C-terminal" evidence="4">
        <location>
            <begin position="351"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8067178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="821" mass="90303" checksum="9B7007EBCAE784F1" modified="2025-10-08" version="1">MATRDAGNRPRKPIATYGKRKTQPARALYSGAKSTTRPSDRQIASSSITGQTTRLLSSERKRKVADLYSSKAIGQDPLAERDDSSPIRPTARRSRISSPEPSHPAKQATKPPPTPMASTSNGAKNGKAASKRKETHEVFTPQTMQTFGNLAVTDKGRARPRMQQQIPVRLAQRRTTLKTTQPDIGPTTTSTASASSAQPAVKGVDEAEKQPKRQKTRLIDSLKAQIQSSDESEDDERESQVTWSQPLVSGQTGDFGQEDSQDSMTLTPNPRKASGTRPPAFSRTSSQVKRTYGQTRTLLEETDMYAALELPQETPALKGRRLEYDIHKKLIKPDSDDEDADLSSMSKTAKMQGIHELRAAGANTFVADQMHDLTEQIGTPNGAGQKASSSRRTALRQVAEKVKEKEYRRSLRDHGVETTIFEHADREHDTITGYLIVVILLQLLAHTDSSHIVRIVRTGSMGDLFARLLAVDNDTVKLARDRKSNLSKRDQTLLGGLQNNLTELSAWRTKPAYISPRTATLKCLQLLVAHDPNIGRDLSLFPATVTDKLFSVLSVAQDPDFWEAPDAIDRINVFHALSVLEYHTVKALESQNDSDKWLTDYLPSVADAFGAVLRVPLDTELESLVMRLVVNLVETVPGAPEVFVAKGLLPTLATSVCASFAKALATVSTNEWSDEVRDGLVLRLGILINCAEQSVAVREAVWKCYGDDGSPTNKLIKLFLENHASTAEADSDAKSQLNVAFGYLAVLLGYLSLLKPFRVAFRASHSKKSMKPLLDSIREFVVHHKVMEAALKDAVEGDAHDGYTDKLQLLVEQIENEAAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V825</accession>
    <name>A0ABR1V825_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662967.1">
        <property type="nucleotide sequence ID" value="XM_066817275.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050335"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF1">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="4"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="215" mass="25257" checksum="C93C5A17EABCE767" modified="2025-10-08" version="1">MRVFHPFSRLPPELRQRIWSLSIKLQDLAVHSLWGPPSLYKQPALLYACSESRNYLLQRHYVPALSDPQRLGLPHQWLNLEVDTVWALYPALMRVYPIEHLQAQNLVIGNAFNQDFFDLCHSELKRMPALRNVTVIANFSHRDSLDPHVRDGYWWLPWTPVLESLYYNGKGAPAPYRLCVAAPKTDHTWELSELNPDNYRERYRAEARIICPNVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8C6</accession>
    <name>A0ABR1V8C6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Catalase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662981.1">
        <property type="nucleotide sequence ID" value="XM_066817289.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050349"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="26749" checksum="8EE6630E563A73CB" modified="2025-10-08" version="1">MDDWEDTVLSSRHIHNRVGGRAGKSKAGDKSHGGGAFDVRKSFGTYEVKLGKGKKASSSTLEILRPTADSAGVVGDLHLEGAVTATILMAGSRKALSRIIDDFGDATGDSARESGSNEDIEGNQIDGDSIVSSGTGDGTDTNLVDTGTERESLEERQQGRFETFEKSSFRSPKFWLRFHGHEPQSDDGAAERSGTGYLVFSGNDCRKFEGTISCDAINWDNKKLSGWKTIARSERDTPVLWHDQEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VA94</accession>
    <name>A0ABR1VA94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Retinoic acid induced 16-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663974.1">
        <property type="nucleotide sequence ID" value="XM_066818282.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051342"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019384">
        <property type="entry name" value="FHIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705:SF11">
        <property type="entry name" value="FHIP FAMILY PROTEIN CG3558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705">
        <property type="entry name" value="RAI16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10257">
        <property type="entry name" value="RAI16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="764"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="881"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="942"/>
            <end position="953"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1009" mass="111794" checksum="CC3B2C755314451C" modified="2025-10-08" version="1">MDFWTRLLANTPLALGNPNKDAAKDPVRRRHRFEKEYSQLLSIWRNTTNLSHDIDAAENLEIRLQELTNLLVEESRRPLPHPCISFCAIKQIYVPIAKIATSSYNEWIIKEAVLFFATLIESEEEAFVENDAFSASLTNLMIRITGANSVRLATDTEIRVVELAFNITTKIRLEPAILSAWFKTHRHDGAAQEDEFQDERDKFAGKTQKQDFPLFYLLLDYIHHEGKVGDFARTGLLYIIESASSSVELERWIVESDLSTLMATGLGALYSQLSRKLVIDHPPHNLPPVLAFSDYEHPTSTSEIVSSCSPDFQLHLDTFLSALLFWQDVLNHCRSAEVKSTLLEHFQVIFLQQLLYPSLLQSSDVDGGSSVAVLTYLRRILEALDHPDMINLILHYLLALPDPTNRPSTSAEPAVSAARKRKSMDLATMLKAQTAVVDFTPLLFNLVDLIHSCLKSQNYQTVSVTLQLLAAILKRHHRYAVVTLLRTEEIFGNSAQRTRGAHDQEVEFLTTLAGTVGGQDNFDEVYDNILKDMMSRVESHPCSLKLVAPKLVTTNQKLPGIPDSLPGAPRDVPHHTLSPEDRLWNSLLDILASFFLNPVDTNLALTETIIDLAICGYVSIEGWILRHPSTYAFEDDEDALEDIPLDPDSTEAAELEKLKLMTRCRRRPIWQTSSLPRIMTVLETLANQVTSYRGSIPRFEDLVQQRREAFQTADTIVLNQRPARSASMAVTPMPELVSDDDSSSASPVRPSGFEGFAQRLLSDLAGTPSRSASPRGRKDMHRSSSNASVTPYTPSTKPLPAPPKEFPLNYDTPNRSGVARSYSTGQSQQPSNVGGRDGPVASQVAAFAAVDQSILARRVGFPKEEDVAPIPFNLKKSISIHSTDDSVEAPSTPQSEPRGGEASQANNDDAQGEREEGDASATTPTAANGGRETVHMPPAPEDPNDDDDEEETGSETMGGARPDTADQANEKEASVSHVVTNVIIFQAFVLELASLVQVRAGTFNEVRFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAB1</accession>
    <name>A0ABR1VAB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uracil-regulated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013922</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663928.1">
        <property type="nucleotide sequence ID" value="XM_066818236.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051296"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022163">
        <property type="entry name" value="GTP_CH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005536">
        <property type="entry name" value="PRK07198.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259:SF2">
        <property type="entry name" value="URACIL-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12471">
        <property type="entry name" value="GTP_CH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase N-terminal" evidence="3">
        <location>
            <begin position="102"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="2">
        <location>
            <begin position="335"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8067175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="556" mass="60482" checksum="B5968BCAE6B463EB" modified="2025-10-08" version="1">MASDSASGASMSDVLEALKSIQQVQGQMQKGVESLTHRVNQIAPPSPDPADGKSTPTPVAVKDLTSSPLPPPATERAESAETPMSAAAKAALEAQKSGFTSRIILTTYPKQIGIDPIPLKWGAADPKERGPVVVSRASSTIGKRNAVGAHGGSYSIYFALALASKQLDINHMPDFTNTEPAANIGPFPQWGDKKKIVAMDPWGHLAPWLFADTIKNENVDIRPTIAITKAHMKLPELEDSVRAGRLVPDGKVCLNSSGELAVTKFAVEPVWYLPGVAERFGIDEGVLRRSLFEHTGGSYPELITRNDIKTFLPPIGGLTVYCFGDPAKMSDEKSRLALRVHDECNGSDVFGSDICTCRPYLIFGIEEAVKEAQNGGSGVVIYFRKEGRALGEVTKVSLLSSKPSLAALGAPYKWLGGMPKKEGNSQTNSHDTVSISVVYNARKRGEDRASDYFKRTENIAGVKDMRFQALMPDILHWLGIKKIDRMLSMSNMKHDAIVGQGIPIHERVELPNELIPDDSRVEIDAKITAGYFTSGHRMTEDELKAVQGRMWEDLDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI20</accession>
    <name>A0ABR1VI20_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome p450 1a2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011089</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664694.1">
        <property type="nucleotide sequence ID" value="XM_066815404.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048464"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF5">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="459" mass="50840" checksum="71A18429AA2C20AA" modified="2025-10-08" version="1">MARSKSSLTSPRTGSDVIYVNMLGQHIVVLNSAVAATELLDQRGANYCDRPDFTLFEIMGWGRTLTFLKWGEQFKLHRKMFQSTFSRSNIGIFRPMQLQESRKAVRSLIKGPGSWRESTLLMTTSIIFRIAFGQEVPSESSPYCEMTKAASQATAAGGIAGTSLVDIFPPIQFVPGWINPSAVLRHARVSRNAIQAVHDQPWETNMRAIEAGTAPSSFMKIHWDRFVESAKAGRPQEASLADIKGATGATIIAGGNTTWATILSCMLFLTRHPEAQRVIQARLDMILYPEGQARLPGFGDRCELKCLDDFIMETMRCLPLNPLNIPHKSLRDDVYRGMFIPAGTMVLTNTTALATDAGTYKNPHVFDPARYERGEPYPLGNFGFGRRKCPGNWLALASVYMFLATFLAVFELEQALDDEGKPKIPEPGVSVGLGGHPLPFECVLKVRSQEMARLLMEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIS8</accession>
    <name>A0ABR1VIS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664951.1">
        <property type="nucleotide sequence ID" value="XM_066815661.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048721"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="280" mass="27940" checksum="7823FF2D1204539F" modified="2025-10-08" version="1">MTTTQSLWSNSTVTLTLPCSSCPGGVTTVTSCPTPTPTPAPITPTTPITPTTPVTLPVLVVSPTTIWASGTVTMTMPCPVCTQVSPQPTSPVVYISSNYTWTQPAAGTSTRTHWRHTSRPAASVTTAAPSSAVWVSGSTVTTTIPCSTTMPMPWISVSRAPPAVPVVPAPPSSASAPAAVGTTQVAVPVVPTPVLSTKTIAPPAVVVPTTATQAGPSPPTQQPVAPPTTQQPVAPQPQPSTPPTTTSAPAPAKTAGAASFGISAVSGLLFGLSGAAFALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJB9</accession>
    <name>A0ABR1VJB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665149.1">
        <property type="nucleotide sequence ID" value="XM_066815859.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048919"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047442785" evidence="1">
        <location>
            <begin position="18"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="63" mass="6511" checksum="B47632327EA3FE93" modified="2025-10-08" version="1">MKFTIVASLLFAAFAVANPMAAGGDDLEARSCRGEGNTCNVAVPDGKCCSGLKCNKNNVCVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJC2</accession>
    <name>A0ABR1VJC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665040.1">
        <property type="nucleotide sequence ID" value="XM_066815750.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048810"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42749">
        <property type="entry name" value="CELL SHAPE-DETERMINING PROTEIN MREB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42749:SF8">
        <property type="entry name" value="HSP70 FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G13740)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="402" mass="46363" checksum="DB6D1DA27AF502F2" modified="2025-10-08" version="1">MNFALAKAFKSVGFEGVDVEQNSIKSLFIVSEPEAAAEIVLRQHVEIKWTTSADQIHAGGMCGSSFLNENFQDHIFGLLKKHREIGKNDDVLLHRKAEEITWTQFEFTLKRSFDIYDNPRYYHIRTNGLQDDRQHGFANGYVVVPFDDIRQIFLKCFHQIWALVEGQLEACKARGNRADKVVLIGGFSASRSLRAYLKQSLSKYDGGRIQLIAPTINHGTTVSNGAVLRAFNKEHGPQRFARSSYGLLRHLPKDVYDSKHQKRNHQDTNERTQPAPCTGEPYVRITIEWFIKKNDMIPEDWTRKPIRCQHFVKRCEDPQLVVWEALYVSDSATASFFKKSHARNKDCERIGYIRVDMSFLKQEGRLVPKPLPEGVVGDDYYEVEYDLIMKVHDRDLQCRNPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJE7</accession>
    <name>A0ABR1VJE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011465</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665070.1">
        <property type="nucleotide sequence ID" value="XM_066815780.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048840"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="5">
        <location>
            <begin position="61"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8071262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="35676" checksum="7B95A42DED6844D5" modified="2025-10-08" version="1">MSSIRKVAMFGQRKNKTNSPTHPIPGLRQLRCPNNRRSPQAGFEVTIFTRPAGTSSSSSSNPNPTRSFPAEAGSIVELDYSDVAKLTPALAGHDAVVSVLGPGAIAHEVPLVDAAEAAGVKRFVVNDFGWGQNPRSYPEMVEVGSRRHVAWDRAKEKAKANSGFTWTGVTIGNPIDWALRRFPRMGFNVADHTAVIYDSGTEFFTGTTLEGIGQAVAGVLSHPEETANRFVKARSIKTCQNELLEAFQKESSGEPWTVKHEKVADLLERGLQKHQAGTPGWILDMLVAQLYEEGSARCVVAASREDSDAELLGIRKETAREVVAKALGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJM1</accession>
    <name>A0ABR1VJM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Subtilisin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011642</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665247.1">
        <property type="nucleotide sequence ID" value="XM_066815957.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049017"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="4">
        <location>
            <begin position="559"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="565"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="603"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1019" mass="112933" checksum="740C7B8BB7D6554C" modified="2025-10-08" version="1">MAPHPDNGIIIPDDKEPLDFAHAALGRMSMLAADIGFREKSATAGCLAAELWIAKKAIESVEAAHSEKLERRSFKLMRQLERICCWPNPPAYGRQSILRNLVQPVTRRDAQQAESRACVGLVKFLHGPDFIKQEWFKQLERFSNVSQNRPAMNDGRARQATDAAPDEHPREVNAMLYNVLRDHATCTCLDTQRSGRKYGRHAARLKLKAGIVRLSDSFGFDMLIQSWPAARGHWQDLQLRVKTKSKKNVRYHGDAHGDPTKVCDGELSRPLELGSLCDLVNIRLESRLNLQVQNSQLYQLYEGIPIQQRIGSDPSVPLRRVLETYRLSNKMKLSASKSSRGESLYASNPYFVVAFDTADTGFQEYCESYSVIFRYPRIIALCVVLLEVMRGRAFDLAEFDTAEASINAKWDLASRTVQDSSQWINFEYTDFRSSLQKCLASKTFDQASKRTGSGWNDLKHDLEERRKILYDVLVEPLHRLVGFLGFENALNQIEPMIPSEPRCARPQLPNVPRNPAHNTVAEDKVVWAAIDWIERIGQLSGLICDPVKLSLHKTPVRPVRVAVLDSGYDEDSTFFQTPLRSRQVKGWKDFAGESADPVDENGHGTHTVALVMKLAPTADIYVARIARDREYINEASQAICQAIKWATEVCDVDIISMSFGFESEIPEISIAIREAELAKRDNLLFFAAASNSGGNRREMFPASHDAVISVRQTNANGSFADTNPPADPHGPAVFGTLGSNVPSAWLSNVDGEVAKSGSSVATAVLSSLAHASANPAVETVIEHDHELSQGRGRSVRAGLWAHFLQTVGVGADARRDADVSAEYQIDRLETRYLRDDDGGDPLAAEKGLRARLDEPRVRAVMKARVLGRRVPVYMISGLKIARGLRVRRETRRTVGGGVSGDVPVAPDGVLAGVGGEFGAERRDEQTSSFRGGEEDVIFAYELSVIRLRGRKDRETVEVDILEHAAALLHEEDKPKENEENTEITVGAADVEGIMESGVEVKATKVQDKKGDVVVCAAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJW0</accession>
    <name>A0ABR1VJW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665313.1">
        <property type="nucleotide sequence ID" value="XM_066816023.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049083"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="169" mass="18898" checksum="9DFE73065911FF7D" modified="2025-10-08" version="1">MEARPQDGHKNRINIYQFPSDLVNTLLRYIYAAGNSEMPPKPNPVRTFVQSPAGARNYLSLPLGTSGRRLWCELRHPRLGDQRVIANLYTMSLFFKMPQLGKALVIEAARHGCVIVACHAAGSHVLDKSQLGKLIETAQIASRWREDLSAGDRALDYVSGPPRPLRSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKF8</accession>
    <name>A0ABR1VKF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Di-copper centre-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010571</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664176.1">
        <property type="nucleotide sequence ID" value="XM_066814886.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047946"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046498506" evidence="3">
        <location>
            <begin position="25"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8070368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="402" mass="44100" checksum="9012EE01DEC03EF1" modified="2025-10-08" version="1">MLLADWASFVGGCVALVMPAVVAAAPAKPQCSSTPPLGGGIPMPADFQVLQDRYHEQIIGSLGAQGCTKDSIAKRRSWDDLEDETRKDYIRAVHCLANKPALTDRSLAPGAVNRLDDFTYIHINQTNIIHQSGYLLPWHRLFLWQLEEALRNECGYKDYLPYWDNARFSADQTKSRVWDGNPATSFGGNGAPRTPPEGAALLLIPGLVIDFWLLMPLGTGGGCVTTGPFANLTLTLGPVAKPLRDPVNKYGYLPTPRCLARSFDPSYTGGASLTWGNATAIVSAGDIGEFREGIERLWHRQSHTFIGGDGADPFSPTNDPVFYLLHAQIDRLWAIWQGQDLQARTYTIAGNRTFFGIPLDYAPDVPPSLAANEDPMEMGLGFRPLTREGMPTTELGRCYIYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKW4</accession>
    <name>A0ABR1VKW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664311.1">
        <property type="nucleotide sequence ID" value="XM_066815021.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048081"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="75" mass="8290" checksum="BB9B4C703DFA9F03" modified="2025-10-08" version="1">MESGSAYWLIFSPALAAIVAHLVAYGQDAAYRVGWKLFYVNLACCFASAFIFGTYLRPAAIVRMVCGIPFLYTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTY4</accession>
    <name>A0ABR1VTY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Annexin A7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665597.1">
        <property type="nucleotide sequence ID" value="XM_066813635.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046695"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF107">
        <property type="entry name" value="ANNEXIN ANXC4 (AFU_ORTHOLOGUE AFUA_3G07020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="709" mass="80991" checksum="E561CD08A579F315" modified="2025-10-08" version="1">MSLRVDDSGRRGRSHSPGRRDDERDRSRGRAPAHDPIIMDAVRMPSPPTGFRYDNMEMRAPRRSDYDLDDRHASYRVTSPTDESYYRQSREAVDVHNEYSHYTRRIEPENYSRKIPEKDRDSDKEKHRLTEALGSAAAFLPAKYSQKLDSLVTRDSDSDKELKKKIKKEKLEEDLAYGTASTMPGNFSTNGTPTTPSINFSFANTPKWEYDATDTKPSYAAREGHPNPDFLSGSSVSSSSKHRSRNSWGGENPRYSGANVLTVEPGRRDRSHSRTRSHSPQPPTARMSSLSVNTGFATASHLSLSNAPASPLLESYHGTYQSMSPMPSPLLLASRGPTGSPIEPLSPGYSDDERGEKKKRRARFNDPVDDASSLAKALKGDRRPDTEPLIEILPAMTHSQVMNLRLEYKRLVKTGSERKGVNIAKHIRARLKDEDPLLMKACYTCALGQWEGEAYWANFWYQGDKTRRELLIESIMGRTNHEVRQIKDGFSDKKYRDSLSQCMKTELKEDKFKKAVLMVLEERRMEEYDEYGRPLPVDRHLVEDDVHDLRKAVKSEKGGETAMIQIVIMRSDSHLRDVLKMYERTYKSNFARDALKKSGNLVGELLAHILNGVINKPVRDALLLNHALTSSKKDGLRRELLISRLVRYHWDRHHMAAVKRAYRERYGQDLSDAIRDGTSGEWGLFCRQLAVTRMPDDVRQFEKVEVIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU22</accession>
    <name>A0ABR1VU22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uracil-DNA glycosylase</fullName>
            <shortName evidence="5">UDG</shortName>
            <ecNumber evidence="5">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UNG1</name>
        <name evidence="9" type="ORF">PG997_009419</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665696.1">
        <property type="nucleotide sequence ID" value="XM_066813734.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046794"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003588">
        <property type="entry name" value="PRK05254.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003589">
        <property type="entry name" value="PRK05254.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003592">
        <property type="entry name" value="PRK05254.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264:SF0">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00987">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="8">
        <location>
            <begin position="127"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="306"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="318"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8074756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="395" mass="43272" checksum="6F07731B85C3C5A8" modified="2025-10-08" version="1">MSTLKRKAAAATDANKKSKPNASITSFFGAPKPAATNGASSSSAAGASAPEPPALKFDKAKWVASLTPEQKKLLQLEIDTLDVSWLAHLKDEITSKEFLDLKQFLDREKTQGKKVFPPPEDIYSWSRHTPFHTVKVVILGQDPYHNVNQAHGLAFSVRPPTPTPPSLRNMFIALKKDYPSFVVPAKNAGLLTPWADRGVLMLNTCLTVRAHEANSHANRGWERFTQKVIDLVAARRTRGVVFVAWGTPAGKRVLKVDQKRHLVLKSVHPSPLSAPRGFFDCGHFRKANDWLATRYGAGSEIDWDLTPKKAAPAPVPEAKAEGKDEDKTEGKTEGKTEEKAKGKAEETDEKEKENVVLPPAVVVVGTDEEGEDGSVHEKSELLDKAGENPTVDEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUB0</accession>
    <name>A0ABR1VUB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665773.1">
        <property type="nucleotide sequence ID" value="XM_066813811.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046871"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="211" mass="23456" checksum="9466BEF1386D4DB8" modified="2025-10-08" version="1">MATTKKVQFGQDQHITSTTRPSSPMIGKAIPLTPVYYSKPFSNGNHSHSHSNNRGGLFLAKIEYYNHDPRQRDFCSLEAIDLSSIIIATTAAPPSPRSPASPASDIVEAIEAHQRGRIERLYPDAPSGGFTVGRARVLWNLSVVHPECPGPELTQLPRDEVREQLELMKNRGYVDCINIKIHVARRSREHVRYVTTPQSMASSSSSPSWQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVU9</accession>
    <name>A0ABR1VVU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666298.1">
        <property type="nucleotide sequence ID" value="XM_066814336.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047396"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="13"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="166" mass="18509" checksum="B40831DB2782B7CB" modified="2025-10-08" version="1">MCDTSTDLAIPAFAGFPKLPCELRLIIWNLALEGENSNRLVFIHRPTMRPVPMRSLVSPLLSVNTESREAARKYYTLRLEVVRLPAMESQDSFVDYPPSRPYQPGAIRLCDTYRTLPQSACTYSECTWLLKKGLEIRTGSSSSCRGTTHTFTTTGGPAHTPSTPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW50</accession>
    <name>A0ABR1VW50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Polyketide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_010137</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666414.1">
        <property type="nucleotide sequence ID" value="XM_066814452.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047512"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19532">
        <property type="entry name" value="C_PKS-NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF20">
        <property type="entry name" value="HYBRID PKS-NRPS SYNTHETASE APDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="12">
        <location>
            <begin position="6"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="13">
        <location>
            <begin position="909"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="2323"/>
            <end position="2404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="884"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="9">
        <location>
            <begin position="909"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="9">
        <location>
            <begin position="1059"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2421"/>
            <end position="2467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="2440"/>
            <end position="2459"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="9">
        <location>
            <position position="941"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="9">
        <location>
            <position position="1120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8075474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3884" mass="422070" checksum="32DE8C9CD26109A2" modified="2025-10-08" version="1">MVSQAPEPIAIVGSGCRFPGGSSSPSKLWKLIEKPRDVVKEIPPERFDTTGFYHQDGTHHGSTNVRHSYLIQEDLKVFDAAFFNISPNEADSMDPQQRLLLETVYEAMEAGGHTIEALRGSNTAVYVGTMGVDYNDTLLRDLSTIPTYFATGTNRAIISNRVSYFFDWHGPSMTIDTACSSSLIAVHQGVQLLRTGQSRVAVAAGTQVILGPEVFIFESKMKMLSPTGRSRMWDSEADGYARGEGVAAIVMKRLSDAIADGDHIECIIRETGANQDGFSNGITVPSTKAQADLIKEVYSRAGLDPENNPEDRPQFFEAHGTGTKAGDPKEAAAIHQCFGQYASPDQPVYVGSVKTVIGHTEGAAGLAGLLKGSGIIQHGFIPPNLLFNQLNPAIEPFYKGLQVPTSIMPWPKLPSHVPRRVSINSFGFGGSNAHAILEEYRSSTSAAIEAAEPQPPASLVAQLQAYSEYLAATPEVNPVDLAWTLQSRRSQLPFKVAFSAATIDELQTKIDGKLAPLKANPGVAVGTRANIKGEAHVLGVFTGQGAQWPAMGAELIRSFPWVRQRVAQLEEHLNSLPDRPQWSLVEEMLAGDDTSRIAEAALSQPLCTAIQIVLVDLLKAADVTFSSVVGHSSGEMGAAYAAGFLSDCDALRAAYYRGVVAKLAGNAATGQRGAMLAVGTSWEDAEELVNLRAFKGRIAIAAHNSSASVTLSGDADAIAHAKRVFDEEKKFARALKVDTAYHSHHMYPCGEAYVSALQACGVKVKEDLSPRVRSLLEASDSLSAVYWKDNMQNAVRFADAVKNAVASDPQIAYAIEVGPHPALKGPAVQNIADVRTGAFPYTGVLSRGKSDVQSFSDALGFIWTLLGSRGVSFPGYQSLVSGPDTKAKLSTGRNPASRARPVDASNRPHELLGVRDPDSNEREIRWQNVLKVSEIPWLEGHQLQGQCVFPAAGYCAMAIEASRILAAGKSITVLELHDLTIPRAITFEDDTNVGVETVFSLTSITTVGKVTTADFALYSCPTSATENELELMASGSIKVEFGEPDLNALASTPLSSSNMAPVETDRFYDSLSKLGYGYYENFRGMSELKRRFNQSSVLVDSYPYSTSESTVYLVHPTWLDVSFQASMLAFSAPGDERLWSLHVPTSIRSIRINPEVCSSLPLSQKKLRVTASLANTDDFAASIDIFTEGGSLAMVQVEDLEIKPFAPATEADDRRLFSYTKIANASPEGASIPQGAKPTAEQAELAVLCERVSLHYLRKWQAEITDEDWANAQPHHTIQALTSQIDSVDITLLCAVGENIPAAVRGETTILEHMLPNNLLDDFYKQGLGFAIYNTFLARMLEQFVHRYPHARILEIGAGTGGATKAVLEKIGHKMSSYTYTDISVGFFEKAAVLFKEYSDKMVFKTLDVEKGPATQGYELHSYDVVIASNVLHATSSMQKTLEHTRQLLKPGGYLFLLEITDNGAVRFSNIMGGLSGWWMGIDDGRKYAPTITPSEWHNALRKAGFGGVDAITPEIDTVAWPLSIMAAQAVDDSINYLRKPLARVANKKAPSIFIDNLVIMGGASLEGARLVEEISEVLDRHCGEITVLDNLPTSAEAEAIGSMSTFINLVDIDSPIFKDVTSEKMEGLNRMYELAKNILWVTVNAQLGEPYHMASITFSRAMHHEYNHINMNHLDVPALDDNVSKAIAEHLLRSIAVDEWDGQGGYSKQRGKFLWSKEPECYLEKNQLKVPRVVHNVGQNARLNSIRRTITTSVPAASSNFAVSPAENSALALVDQPLPTTGDAPVVNVKSSSVQAINVAADSFLYVSVGEETTSKDIIVALSLSNLRETVPIVSVAAGGAPESADRLLVGVSSELQAAALLQNVSAKSSVLVHLSGQDRVLASAIERLAAAKSIRVAFSISADQAESATPGTLLSSVKATHFLDLVHDGELSQTVARVLPSATKKISHAELSQAKSQLPPSYALDDLKTRLSEAVSRAKEAPVEGVEGLVIQVAEIGSPSMAAIHSTSAVNWAHEGQVNVQFRKLESEKLFAPDKTYLMLGLTGQIGQSLCEWMIQNGAGTVILTSRNPKVDPLWLESVQQSGSTVKIFSLDVTNKSAIESLVKEIKATCSPIAGVANGAMVLQDCLFSKMTVDVMQKVLGPKIDGSRYLDEIFFDDDLDFFILFSSSACVIGNSGQSNYAAANGYLNTLSRQRRRRGLAASTFDIGRVAGIGYVETAGQAVIDQLTRFGLMAISEAEFRQVFAETIRAGYYVPGDKERIPSSIITTGIRTIRDDEEIQGPWFDNALFSHCIIEAKSAESDGGSSGKKVSLPVTEQLACAANEEQAVKVLQDCFSAKIKVILQLADQEIDPEASLVELGVDSLVAVEVRSWFLKELKVDIPVLKVVGGASVAELCQIAFKKLPEELVATIGTGDASKIAPKASAPTVSEPVATDKAQSPAASSSSSSAPSGASSPKSETSPANLLTPATELGSRSAFPAAAGTSTFLEPKKAAVVARPIRKFLKTEQISFGQSRFWFLRLLLEDQTTSNVAFYYKVAGSLRVADLERAVRMVVARHEALRTAFVEHETRADQAYQKVIGNSPIRLELQQAKSFEEVETLYHQLQQHIFDLESGQLIRIVLVTLTPTLHYILFNYHHIAMDGVSFQIFVQDLEKAYKGEPLGPSPRQFPDYSRTQREAYESGEMADELKYWRSVFPADQQPPVLPLLPMARTASRGAMKVFGVHQVMHRIDADLMTRIKNVCKSRRSTPFHFYLAAYKAMLFSFADTKDLTIGIADANRTDRDVNNSIGFFLNLLTLRFRRQDNQRFSEAVSEARDTTYAALGNSRLPFDVLLNELNVARSSTHAPFFQAFFDYRQGAQENHPWGNTQWEFQEVHPGRTAYDITLDVTDSGNGSLIIFRVQKGLYDLTAAKLLMETYTHFLEFLSSNPESSLDKTPLFSQQQLTKATEIGRGPKLVSEWPETLPLRIDQVAQENESKTAIKDGHGNSWTYSALIQRIEAIAKALQNAGVGAGGRVLVFQTASADWVASMLAIMRIGGIYVPLDLRNPLPRLASVAVDCEPAAVLADKTTVGDFEQLNVPNAALINVSTLASAPTAPVANVSKGTDTAAILYTSGSTGLPKGIMVTHAGLRNEIEGYTSMWKLGAERTLQQSAFTFNHSSDQIYTGLTNGGMVYVVPWDKRGDPLEITKILKEESITYTKATPAEYSLWMQFGGETLRGATSWRAAFGGGETLPSTLTKEFAELGLSQLRVYNSYGPTEISISSTKMEVEYRNQSAMEEGRIPCGFSLPNYYAYIVDEQLKALPAGMPGELYIGGAGVSQGYLNNKELTDKHFVANPFATPEDIANNWTRMYRTNDICHLREDGAMVFHSRVAGDTQVKIRGLRIELNDIESNIVAASNGALREAVVTLRQGDPDFLVAHVVFAPGQEPSDSGAYLAHLLNNLPIPQYMIPVLAIPIDKIPLTNHSKTDRKALMSLPLPQRATSAQEGEEELTPTMTQLKTVWQTVLGNSQLAFDINPSTSFFLSQIRQVFNVTVRLVDLLGDNTLGGMARKIGESRKVESIDWDKETIVPTIPDFLKSVSGAPKSDSKTVLVLGATGFLSKTLLPQLLANPSIAKIHAVAVRDASKLSTITSPKLVVHAGDLVSPRLGLTEETFKLLAGEVDVILHFGAVRSFWDNYHTLRPINVNPTKEVVKLAGPRQIPVHYISTFGVLPRDSTAATSAASNLPATDGSNGYVGTRWASERILERAAETLGVPVSVYRFLPTPEDAAATTPKEILDEFVRFGRIDMMPATQASTLLHDRAVADATAGAAAAKFHHVQSTVAVHVGELREHVTKERGQAGLETMPGLRWIGRIKQLGFSYFLTTQEAAVGGGSQSEAFESRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW83</accession>
    <name>A0ABR1VW83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010174</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666451.1">
        <property type="nucleotide sequence ID" value="XM_066814489.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047549"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044990986" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="27"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="103"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="280"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="408" mass="43240" checksum="9B4793A7F7886F88" modified="2025-10-08" version="1">MQLPTALLLATGLVGGAAAQTQYDEELTVNTTSGRYTGFVDTATAPDVNQWRGVRYGQAPEGARRFLPPVAAEDDGLHRYARDWPTVCVQQGATTRGSGGSCYRLNVFGFPGANGAMTNAGFLDARLVVEWAKNNIEAFGGDPERMVLWGQSAGAGLTASYVYANGEDPIIAGAIANSGTVGIGPGSDDDSGSVNKFSQLADIVGCGGLDAESELACMQGIPAQTLQSVLQSRREDVPTFGAVPLITGTTSNEAAALGGGFDKNATTPPPKPPNNPVGGFDCSLREELKDRLDNGHITYRYLFAGNFSNITPRYWLGAMHSSDLPLIFGTHYQFRGNSTELEWQTSYAMEDMWVAFATDPYKDPSTSSGLVWPKYSLDGETVVLFGNGTEAAQLAPPSVADISDCSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWE0</accession>
    <name>A0ABR1VWE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Isoamyl alcohol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010202</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666479.1">
        <property type="nucleotide sequence ID" value="XM_066814517.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047577"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047048933" evidence="3">
        <location>
            <begin position="38"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="141"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="626" mass="67530" checksum="DFB203DE2E1C0902" modified="2025-10-08" version="1">MLQNADQSMGRRYSGVGTRSLLLAICSALAASIAVEAATDSNTIWTSLNTTLTGRLRQSEPLARPCFPNFAGQPVPLDEAACAAVRTNYTTNLFRDAQPAGYMNPQSEMCLSDPADQCILDTTTNTTAPAGMPSPNATCGRGGVPSHYVEVQSASDVLAALDFARAHRDSDGVYLVVKNSGHDYMTRNNGGPGEGMEFHDCFVPDGCSGAETAGMRAMTVAAGESTGDAFAFAAAHDSLVLGGYSPTIALSGGWILGGGHGPLAPVYGLGADRVLQMRVVTPDGVERVATAYNEHADLFRALRGGGVGGAFGVVLEATHRLEAGPLPIAVASLKLPNDTPTDTVLEWIELQTQSSLRWGREGWGGHVAGLYLTHFNPLPAIANLSDTSAATASMREASDFVLAHGGTSAVEVLPDFLPAWNKYVVPGATKTAGNARFISSRLIPQDMFADEDGVQKIMSFLKSLPTDRWNPRNLYVPAATPFVAHTNGTYGRPLSTVETSAVHPAWYTSLWALSTAFTLPWNATYEERLDTFTWFTEVTQQQEILTGEKGGSYVNEANLFTQDWREAWWGSRENYERLLETKRKYDPQGLMNCWKCVGFEDADLVGERFRCQGKLQMAIDERIGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWX4</accession>
    <name>A0ABR1VWX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666642.1">
        <property type="nucleotide sequence ID" value="XM_066814680.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047740"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047010902" evidence="1">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="116" mass="12651" checksum="03E80211608CE893" modified="2025-10-08" version="1">MKPSTVLSTLLTAVLLPAAQATWCTFYFDSKCTKHANSVDFDCNNMNLFSSGGSYVSCHPGLNNDNLDCLASRCSDQWCQMDPLSMTGVPANYTCTSTGGPGPYYMLAEWYNEGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX67</accession>
    <name>A0ABR1VX67_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NPR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666774.1">
        <property type="nucleotide sequence ID" value="XM_066814812.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047872"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009348">
        <property type="entry name" value="NPR2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991:SF10">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991">
        <property type="entry name" value="NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06218">
        <property type="entry name" value="NPR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="197" mass="20780" checksum="D9FC134AB853CC12" modified="2025-10-08" version="1">MKLFPYHPPPAPVRGWHVPVPKMKLVDIVDPTWDLTLQKIIPHVDGVNDVRRIAWLADVSLPLTQTALQHLLYYDTILLLDMFFFASCYAPRPGIHDFITNRDGLIDECAGYVCIGGPLPDGAGATSAAGAAATASSSTNLKNPNPAAAEPSTPQQTSTIPGSTTTTLTPTPPPTQPPPVPRAPPPAASPTTSSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXG4</accession>
    <name>A0ABR1VXG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666822.1">
        <property type="nucleotide sequence ID" value="XM_066814860.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047920"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="294"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="362"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="478" mass="52409" checksum="9ECE133F8AEF566D" modified="2025-10-08" version="1">MQHHQPSSLGHPSTASKDLHNRQRNASIINRQSSIVATSSNLPFLVIIDAASPRRSSINTSDAKQPGACTSRPVPYSTGSTHRALGRDLSSPRPSRLRSRGKEELARSPSVEPGATLSLHSDRVALHRRGPVCARISGSQRRAHRRLPATVHPLKLKGIFAHAPVHVHVHPSQIQSPTYHDDIDAPDDVRAKLPGRLARFSMTLSEPARLIIPSNTPSPLRARSRASGMVLDALRSLARATELSIYMVDEEASRAHLQPLCALLAAGRAAPLPPYTETARLFGGSGGCRWVDRTLSPPPPLPPLVDEDHSSLPPPRYDELGPGPPMPPISSQEARLARFSPRSESAESSAVLQRLTMLEVLVQAQAKQIEELLADNRQQKERIRECEVDIGAVRLAAERAHGRVEELELEMAVQRDDMERLDGEVQYCREFQEDEDLVEIVASTVSDRISDNVTDAVIDRIATRGLVARNISFSLGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXP2</accession>
    <name>A0ABR1VXP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666547.1">
        <property type="nucleotide sequence ID" value="XM_066814585.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047645"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050829">
        <property type="entry name" value="CorA_MIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47685">
        <property type="entry name" value="MAGNESIUM TRANSPORT PROTEIN CORA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47685:SF1">
        <property type="entry name" value="MAGNESIUM TRANSPORT PROTEIN CORA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="622"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="651"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="707"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="728" mass="82416" checksum="EB08E6144A3E3F82" modified="2025-10-08" version="1">MATSHPYGRNRFRGVEEVKPYSRRLSPLSSIIESDTGTGTSTQDVVVFMPYLHWEAYSRRQRYEKVVDKAIRDFEEEEERKSRRGQEGELHRPDQSRHSQSSSSSVHESIVRASSSSREADTPPPASTATSGEARLATFLDRFDRPRPSPPVDRNGRVSVQNPLRQYLLDAARLFQGMAEYGDKSVIEKYLMSNKPLHPRRTLGQSYHWTLKDGEDDSQSQVLYRATKPRAFHLHHPGSETGPEHHDFALTGDCEKCREDSHKFPSIVMVDQLWMWILNSRTVITCFPGQHGSKRHESSGVDKSIRARMQSSNSRLGSVFELGLVVIDECSAALFGGAKDATDGQPELVNVFSAKIGRIRNRQQFLFKQFWQWATKIERKIQAEGNSADVKVPLNLFTEGMLIRELKDMIEELGIMIHTMRTQRDVVRAYIANAERVLDPLNDFRSNTQRIYVSRHRKRNPLSGALEEIDGDNEEEKQRAAQEDRFYRFRSHADECSAKIRARVESLEGLREATNAGVESVKDLLELKGQQASLIQARRSTAQTEEAMAQTKETMAQTKETIAQTEETVYQGRVILMFTLDDSVPVSANVRPLKLPLSFMSSIFGMNNVEFGSGAWLIHDEIVYMVAVSVSVIAVSLGLAFNAWLRAFFWYLYKVATARVLVSTGLYGFWLRFGVPAETLETRGNRTADGLFRDAAAAVRAETRAEHTLAPPPGMQPRRRHWAESQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZK9</accession>
    <name>A0ABR1VZK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666228.1">
        <property type="nucleotide sequence ID" value="XM_066814266.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047326"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="8602" checksum="C3788B3C00C308C4" modified="2025-10-08" version="1">MPVVRRPAPLGVLGRSGWVDAEHGNGRNQGLVPHALGGAGLVVPYERAESAVANWVVPDDATTAKSTSPCQSAPPGSVHLLLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZQ3</accession>
    <name>A0ABR1VZQ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666741.1">
        <property type="nucleotide sequence ID" value="XM_066814779.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047839"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="344" mass="37263" checksum="57636D96C09DE6C1" modified="2025-10-08" version="1">MSATTEITLDVAKEMPQVTLNVPLAAEDVNEPISFSQPLNLSFEENGGQLSSEPQTNRPDELSIPRKIISSTVSSSIFHSECLRPILAGTYNGIPAYLVRLQFQLVASAGGSNRGWSSRVKGATIKVLFQDAPPPGGYDSDLGDSEDSDDDEPRHPSIVKTMPGPEGWQGQPTTAQVEDKSEVGLQLGWDAVGVSATKSRQRTKAKTGAIRMNAVCRGHDCNSLIIFVAEDSVDAAGIPEHMTIPLIVTVPPQTHACGKGRRFSMRVEVNARFGFWRHGLLADIVPVLGRVDEPLYFDPGVMHQWMEEGRKGVGGIKVVQWLGELEGVNLEEYFSLSGLGQATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZW7</accession>
    <name>A0ABR1VZW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Restriction of telomere capping protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010373</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in a process influencing telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RTC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666650.1">
        <property type="nucleotide sequence ID" value="XM_066814688.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047748"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF130">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="7">
        <location>
            <begin position="345"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="142"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="407"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="628" mass="69500" checksum="D40F887D3D255FD5" modified="2025-10-08" version="1">MGQAHSEEVRSKEDIAAELAEKFARKCFEPLELYCFKDNFRSLADHEQHIRYLKEDVIAKFLELPDVLNVSPVVFQMLSYIGAFPFLEDAPAVLGFEQMIVCVAILTDRYTKSLAKGAATRRKLLFKSMAVYDRKLSEIEKRPASPTVEAGEDDAMAGRSHAPGFAVDEAGDDDDDEGVEDADDDELVLAALDSLDLNDSFKTGDLHAASTHGAMIPADNFRRLIMLLLLIAPLSPPGNILDGLRDTANSILSSLINVERTPGITFAQFQRILPANLPFLFQGFNALFEHFLFSRNLDFTKKHKWTKSGSDIDTTASPPPSPPAIRRVRTSSSSLPPLLPDKGQHILNPNIVSQLSFFIPGNELFRRLRLLYSGADAGFSMGSFETKVFNWRAPTLLLVSGTRLTESSDSHHHAQGAEGSFMDSLPPRRFPDGSPAGRSEDRVVFGVLVKQPWRAAHRECFGDSDTLLFQLSPVHDVFRASVVNQNYVSFAKTPAAFPGITVGCPSPKAATQSRHPTIRTLGPVSLVIDSSFEFGVFTHDYTSRGGAFATSSARRYDFQDRFQVEDIEVWGCGGDEEAKGQRERWEWEHREAEARRRINLGTGDREADRALLEMAGLVGNNRSGGSMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W943</accession>
    <name>A0ABR1W943_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phospholipase D/nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_007826</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667483.1">
        <property type="nucleotide sequence ID" value="XM_066812141.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045201"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09123">
        <property type="entry name" value="PLDc_Tdp1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09194">
        <property type="entry name" value="PLDc_yTdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="485" mass="53747" checksum="85875350765320AA" modified="2025-10-08" version="1">MSEPPAKRRRLSEGHDPPPADVGAASGSELGPASLTRPISPPPRKRVARQERLLMPSPFQLTTIRDLPAESNVGAVSLRDLLGDPLILECWDFNYLHEINFLMGHFDEDVRFSVKVHVVHGFWKREDPNRVALEQDASAFKNVELHTAYMPEMVGTHHSKMLVLFRNDDTAQVIIHTANMISKDWTNMTNAVWSTPMLTLSEGEENQDFTIGSGHKFKSDLLSYLRAYNTKRSVCRPLVDSLAKFDFSAVRGTLIASVPGRHAVETDPRETRWGWAALKQAMRSIPVQPGKADVVVQVSSIATLGGTDSWIQRTLFDSLSSATKSTSRPSFKVVFPDASEIRRSLDGYASGGSIHTKIQSAQQAKQLQYLRPIFCHWANDSEKGTELPKGVAVRDGGRKRAAPHIKTYIRYGEKSIDWAMLTSANLSKQAWGEAQGASQEIRVASWEIGVLVWPELLADNAKMIGTFKTNSPPPSNLRAISLSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB64</accession>
    <name>A0ABR1WB64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pentatricopeptide repeat-containing protein-mitochondrial domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008558</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668215.1">
        <property type="nucleotide sequence ID" value="XM_066812873.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045933"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057027">
        <property type="entry name" value="TPR_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23276">
        <property type="entry name" value="TPR_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Pentatricopeptide repeat-containing protein-mitochondrial" evidence="3">
        <location>
            <begin position="355"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="632"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="653" mass="73965" checksum="D3CD7133D9293C9B" modified="2025-10-08" version="1">MPGERIVIDGLWRCLCPSVDAKALSRVLQQPPLVPPRRTSAFLDHTDRTYAGPACTRSYSDVAPKKAFKKATRHLENITRIHPKPKEKEIVRVPNRRRSQAQDAYERYFDRMAKRLPEIPPVLLTGSPPPDSELDPIDTSILLTSLQELLTAQWQYHTIVAIVQHLVTKRGMKPDAFLYECLIKINVDPMYGSAQVVENLLKEMESTGCLPTSAVYHGVLEVLAVHPDYVLRTKVLRAMKQAWMEPTFQGLVAVTVGLLRDGQYEMALERLEKMNASDMAVPPWLYDIFVYTFTEMGMHAEALMILQRRLRDPDSGVTDNLWYALLEAFSRDSYYDGVSYIWERKVAPGILAPSDGTVLDVLNTASRNGDASLVTESLELLSKRGKKLELHHFEPLLDVHAREHDLRKAFLTLGLMVKAGLQPDSSSTREIYTVLRDSAEKTDEALEMLLEIGINDQIPMAAFNVVLEAKLQHQGFKSGLDTYRSIRRICASPPNLATFHLLLSHCTLLKSMQFLLAEMEGFSVKPDSYVYNRTVLICTLNPQYEHAFRYLDRAKSVTIEGEVRNWWMDRDTALALIRRCIIAEDSRVQGLIETCKERGMDAIESDVRDLVYRLQQWQGLENEQLEEPVVLEGETALPVSPATPELEAQGSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC44</accession>
    <name>A0ABR1WC44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668472.1">
        <property type="nucleotide sequence ID" value="XM_066813130.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046190"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF78">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="596" mass="64464" checksum="7FEEEE75976ED9D5" modified="2025-10-08" version="1">MPLYTQLPDEIKKVDVIVAGGGTAGCIVAARLAEANPALAVLVIEGGRNNADDPAVAHPLLFMSHLAPTSDTTRLYTGGAEPQIGDRQLAVPAGGILGGGSSVNMMQYTRAQRHDWDSWKAEGWSADEMIPFLRKLETYQGPGKAEVHGDEGPIFVSEGSYVAKRPQNEFIKAAAQLGYPEHVDLQDLDSNNGVQRARRFVSADGGRSDTAHAYIHPKMKGEGGKYPNLHVLLKSQVVRVLFEGQKAVGVEYRGNPKFQNTPVRSVRAEKMVVLSAGTFGTPLILERSGVGDQAILEAAQAPVVAHIPGVGQNYQDHHLMTYTYKTALNPDETADAIIAGRVDMGELLQSKASILGWNAQDITCKLRPNDAEVAALGPEFQAAYERDFKDNENKPLAMMAPASAFPGPPTPDMEPSQYYTVTAFTVYPYSRGHVHIKSSSDPDAPIDFATDFLADPLDVKKHVWVYKKQREIVRRMPSVYRGELPGTHPPFAADSGAALLIDYEPNTPTEAVKDIVYTPEDDAVIEQWVRDKVGTTWHSLGTCAMAPLERGGVVDAKLGVHGLRNLKNVAANTANTAMAIGERAADIFIKELGLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE28</accession>
    <name>A0ABR1WE28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1275 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668226.1">
        <property type="nucleotide sequence ID" value="XM_066812884.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045944"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488:SF7">
        <property type="entry name" value="DUF1275 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="28742" checksum="625D0AB44D0310D0" modified="2025-10-08" version="1">MMPNPEKLEEAQPGSGSGSGSEQEQIPTVKGKLSTHFSSSVDTRAGYIPLLVLCFVTGLTDGTLYNGNTIFIALGTSGQNNKPYGWARSLCSLGCFAIGCVSFARLHKLIGGPRLRRTLLFSFSLQTICVVVAASIIQSGIIDGTYPARGNPNNVNFTELAAVALLSFQAAGQIVNSRGLGVSEVPTVVITSLLCDLVSDEHLLVGLSKNGKRNRRAIAFVLTLAGAICGGWVSKATHQVGPCLWLVAAIKGTITMYWMGWIPLLKTMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEE4</accession>
    <name>A0ABR1WEE4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668346.1">
        <property type="nucleotide sequence ID" value="XM_066813004.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046064"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="93" mass="10747" checksum="3EE5CAE61694806D" modified="2025-10-08" version="1">MEHHLDLEDLVYHVNPTFNRTVFSSTNVCFIRLDHQRPTLADFAGQLPGPGPHTAVDLLNHCTKPSWYEEREVTEVVEDEETEDAEHAEEEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFD9</accession>
    <name>A0ABR1WFD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate aminotransferase</fullName>
            <ecNumber evidence="7">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008702</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668359.1">
        <property type="nucleotide sequence ID" value="XM_066813017.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046077"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF55">
        <property type="entry name" value="GLUTAMATE OXALOACETATE TRANSAMINASE 1, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="8">
        <location>
            <begin position="64"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="445" mass="49100" checksum="4FD9F33876F41B40" modified="2025-10-08" version="1">MPTNNPSNKFDPSYHANSVRRVHSIAKQMSPPSATSFTAEVVPQAPEDPLFGLMRAFKADESPDKVDLGIGAYRDNNAKPWVLPVVKKADEALRNDPELNHEYAPIAGLPFFTSKAAELILGGPDSPAIKEKRVTSVQTISGTGAVHLGALFLARYWTGNKKVYISNPTWANHNQIFGNVNVPIASYPYFSKETKGLDFDGMKSAILGAPDRSIILLHACAHNPTGVDPTFEQWKEIAQIMRSKNHFPFFDCAYQGFATGDLMKDNLAVRHFVEQGFELVIAQSFAKNFGLYGERAGCFHAVTGPAPDAESTITRMASQLAILQRSEISNPPLYGARIAGTVMNDPKLFAEWEENLRTMSGRIIDMRKSLRAKLEELGTPGTWNHITDQIGMFSFTGLNEAQVMKIRSDAHVYMTKNGRISMAGLNTGNIDYFAKALDKVVRDTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WGJ7</accession>
    <name>A0ABR1WGJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668688.1">
        <property type="nucleotide sequence ID" value="XM_066813346.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046406"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8081213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="97" mass="11135" checksum="96769A338C8370E7" modified="2025-10-08" version="1">MERQHRLDAQLVYTEDGYLGLSPEGEVGEGMAVAVVGRAFSLTVLQRRTDGRDAWYERCNRVVFYGWDKGKIENLQELDEHSEVEAYWIGLRTGDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMJ5</accession>
    <name>A0ABR1WMJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005518</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668756.1">
        <property type="nucleotide sequence ID" value="XM_066809833.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042893"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="44"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="46443" checksum="C377A6B1316029A8" modified="2025-10-08" version="1">MEASNRAIMAPEDIDHSLDHEGRIKEIITILSVFSAVATLVVALRIYTRAIILRSFGTDDAVIIGALILTIGSAVAIGLEGKFGLGTHTWVQPLEDFIPYMKSFYVSIILYNVGLCLIKVSILLQYRRIFTQKLTQWMSGGLLGFILAWTVTLSVLLPLVCYPVDKFWEPALPGSCVDQLAVWYVMAGVNIITDFAIFVIPLPVIKSLQLPTKQKMLLVVVFGLGLFTCVISCLRIRTLKMASLTKDPNWDNTDAALWSFIELCIGMLTSSLPTLRPLIAAALPRQFGSSGRRGYQDYSGGEYGASSKSRSLAFSSSARKSGVGGGKGTLPLKSAASDSLEELHQYRFGAGDHKDIELGIGGGGGGGRGDVTPGYSVAVSCGENYDAFEMQEPAAAAVAAPKRAMSRQGGNGITATTVVTREYEPSVRNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP15</accession>
    <name>A0ABR1WP15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669794.1">
        <property type="nucleotide sequence ID" value="XM_066810871.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043931"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="127" mass="13550" checksum="A21F4F90DA887DD0" modified="2025-10-08" version="1">MSSPFHINATCPSLEELPDAWNIAGLPLNITTYFTPAQDAWYQPMTTCCSPNPVGLADGCYFWCEQPPSHPDLSDWSSCVRHGAVNGSKSSITAVHKAGAAGFQTGAPDKMVMVVLAVLVGSTCAWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP61</accession>
    <name>A0ABR1WP61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669798.1">
        <property type="nucleotide sequence ID" value="XM_066810875.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043935"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24232" checksum="25B17981EACA929B" modified="2025-10-08" version="1">MSTNTTERPLPYLPAEIWVIVIRSLANSEDFADVWNNGRRTSRHFKTLIESVFRIHILPVMVANLSLRGSPARAGSDRALLEFKGLSDDGERACFGEKDQASRGTGGPKLQRNEIRHGLAANQFSSMAPPSLPCSPPVLIEWASHLCVSVARGPTGFVGNHGTEEPAHHAWFEPGVAPAMQMRVDQRAAEVSFLWKSLLSNFAASLENHAISPGPKVCPLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWP6</accession>
    <name>A0ABR1WWP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CVNH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670472.1">
        <property type="nucleotide sequence ID" value="XM_066806854.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039914"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014">
        <property type="entry name" value="EXPRESSION LETHALITY PROTEIN HEL10, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014:SF1">
        <property type="entry name" value="EXPRESSION LETHALITY PROTEIN HEL10, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="264" mass="27356" checksum="86D7166E015C6F57" modified="2025-10-08" version="1">MSNSEYYSGAGGGGQPYGGGYGQQQQQGGHTPPYYNPPQNQYSAPPPPPSGGQYGAHPPPPQYGGPPLRATRAIAADINHRGWGGQQQQQQQHQPYPPNSGAPPNSHSPGFGQPAPHDQRGGGYYQQQPPGQHQQQGGAYYGHQQQQHWDPNSAPPPPGQQYPGSGPYPYPPAGASDKGLMGAVGGGALGAFAGGQAGHGFLGAVGGAVAGSMLEDRFGGKKDKKKKKDGKDKKDKKSKKDKKHHKKKGSGSSSSSSSSSSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWY9</accession>
    <name>A0ABR1WWY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670575.1">
        <property type="nucleotide sequence ID" value="XM_066806957.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040017"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="461" mass="52204" checksum="87FC06F2C33A992A" modified="2025-10-08" version="1">MRWKTTDESSFALQPIDGPAIFEAVVDDEGASSKRQCQLTWPEIDDWLNPKAPQEFPGLSETQDHQQFSLRIILNLTREGWAKILSSFELHESTLDAFLDDNGAFGSYFYRSATSNRPVNVIKLVLKVPNKISIGYDAVSLAYNISAKSVTALVHGLEPAHWDTLVALLSQSLHLCRHPLLLPALMLTTHRKRIEKYRYDIDRSIVYLEKETGFGVAGFLRGSRFQNPDLDLESALVRLQSQQTELANLAVVLRFSEKWADLLLNSIARLSQSPLVCDQDAVLQLEDEMLHLLELPRNQVQTSLSQTQALKDRVQSQANLIFSLISSEENKISRFIAEENSKVALSSKRDSMAMKTVALITMVFLPGTFVATFLSMPLFDWNADTGGTPSSSPFQWIYWATTMPLTIAFMVGWWVWWKLEDRKWDEELERAKEENQRALGRTTTADSPAYSPGYSFDSRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX04</accession>
    <name>A0ABR1WX04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002658</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ankyrin SOCS box (ASB) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670591.1">
        <property type="nucleotide sequence ID" value="XM_066806973.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040033"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051573">
        <property type="entry name" value="Ankyrin-SOCS_box_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24136:SF15">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24136">
        <property type="entry name" value="SOWAH (DROSOPHILA) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="154"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="183"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="231"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8087697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="30467" checksum="5DAD4C5582CCDEFC" modified="2025-10-08" version="1">MADATGDEKARFEAQAIAAIEANDPASLRTILVQRLAENPAALRPGDLGDALNKALELSRYDMADELFKRGATWNYGTMANVLEGAREDNDWNTKAIDVALANGWDINEHYEHVGGALVYTISSAESGGSDTAALKVAAHLLSKGADANEGQQTGQNPLELACGMADRDMVALLLAHGATVHKGPKALLEAADQGSVEVMRMLLDQDADVNAHPYGKYTLPMYVNDEGWGSALHCAVKGGHADAVKFLLEEGAEREYRNKVGVTALELARKLGREDIVRLLESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX55</accession>
    <name>A0ABR1WX55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar protein 56</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002638</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670571.1">
        <property type="nucleotide sequence ID" value="XM_066806953.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040013"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="7">
        <location>
            <begin position="300"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="452"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="471"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8087677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="516" mass="57161" checksum="4932FB408D1F666F" modified="2025-10-08" version="1">MTKIDYLLHESALGYALFKVVHQQDTVGLHLKEVQAAQADLAKFGKMVQVQAFAPWRNAADALENVNSVSEGIMTDYLKSTLEMNLPSSKKSKITIGLADKNLAGSIKAVFPGVECETGDTSDVAADLLRGVRLHAHKLLKGLEEGDEQKAQLGLGHAYSRSKVKFNVHSSDNHIIKAIATLDNIDKSLNLFSQKVREWYGWHFPELYAIVSDNITFAKLALYIGNKTSLTEDKLHEIAALVDDDEEKASEILNKAKISMGRDISATDMENVSTFAEKVVKLSEYRRTLFLYLSEKMNTVAPNLAALLGDVVAARLIQKSGSLTNLAKYPASTLQILGAEKALFRALKTKSNTPKFGLIYHSTYIGKAAPKDKGRISRYLANKCSIASRIDNFSENPSTKFGEVLRQQVEDRLEFYATGKKPQKNAEVMDQAMADILGSGESMAIDTEMIDAPIPESAGANEKKSKDKKEKKEKKEKKEKKDKKRKQSEDAEEEPEAAEGEKKKKKKKRQSDVAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXF4</accession>
    <name>A0ABR1WXF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome b-c1 complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Complex III subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_002760</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UQCRQ/QCR8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670693.1">
        <property type="nucleotide sequence ID" value="XM_066807075.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040135"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.210">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004205">
        <property type="entry name" value="Cyt_bc1_su8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036642">
        <property type="entry name" value="Cyt_bc1_su8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12119:SF2">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12119">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02939">
        <property type="entry name" value="UcrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81508">
        <property type="entry name" value="Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8087799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="70" mass="7904" checksum="A3365DE2EB040EEB" modified="2025-10-08" version="1">MSPRWENTASVAIPERGIITYALSSNRQNILAGAAHAAVFNTWRRFAGQVLFWAPPLVAAWYAMEWANKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXJ5</accession>
    <name>A0ABR1WXJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">VanZ like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670787.1">
        <property type="nucleotide sequence ID" value="XM_066807169.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040229"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037970">
        <property type="entry name" value="vanZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ-like" evidence="3">
        <location>
            <begin position="34"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="219" mass="24396" checksum="E21F2E66D92C813B" modified="2025-10-08" version="1">MHIRLPFAGVFFLLCLLAGYVGLSSLQLNYYVNDKVLHLFTFFLLTVVFYWIVDTNRRRTSNLTLVVCTAVLGIGSEFLQGFLPNGRVFDLYDIVANVVGSLAGLALCNWYHKRMLERKRSRRYNAVPGEDVEDVELGESSVLTDADQEEGIMSAAPATSERAATGKTLEEEVDTWDENAVDNWDEEDDGDIGTIPKPKGKEPEPVNGADSVDAKKRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXP9</accession>
    <name>A0ABR1WXP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670821.1">
        <property type="nucleotide sequence ID" value="XM_066807203.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040263"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="590" mass="65091" checksum="59BB06D52FDD9E04" modified="2025-10-08" version="1">MGGLIPLLLPSGGASRIVPSGGYQSRRRASVQEPSSPSAPTHRRQHSLPVVVSRNPRRPSISTSVQQLTVLPYTADEWKKTLSEVKQKYLNRKYRTCSARCCEILDNLKDLSNVEPSTWSICTSTPLRHSRCSSTYRTKLLRDAREHYEDAAILIEKAEEVTTQKSRSGSVSSTASHSPSLSLSSCMNASAMSPRSSMSSGDETPGGGKRPTKKKKKVSFSGLPDLEEVTKPSLQPDPYMRPDSPTLGWEESYYLFGTPEPESQQQQSAASVSAPLASVAETEPEPASPAPSPRDRLAFPERSSTPAPPADDDGHTFNLELFLQTRSMNRLVSQLSALRSQIAYHRDAIEGLLVTSEEAAEVPSVPEVPPVPSIPGLTRNISPFSASSSSAEDSDGPPTPTSTTVAVFEQHANYSPKTQASPGFFDLEAHMRRMEEEQHQFQLQQQQKQQRQQQHPTYFTVPDWSKDNSNNVKNYSHGRSQSSTGPYYIPSEPWMARPRSSDSDSSDATMTPSMNARQETSYYHQVQIQRPASAASIARPGATVPSASTVSDEGLRDRIERLRAGGWQRKRFDNRRYEALREQVLGELGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY23</accession>
    <name>A0ABR1WY23_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670943.1">
        <property type="nucleotide sequence ID" value="XM_066807325.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040385"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="547" mass="63866" checksum="E5124E88B1FDA82B" modified="2025-10-08" version="1">MRRLPDKRGEPWESIRHYLEATFDVRLPPGSKIAWVAAQAAMGLKGMRFTLKHHDAGHLLHGVSPLARLDCGMAESFEHAKSLEFSLDDWYWHWKGGPEDIAKFFRHLVSRCSLQATSHTDPVLLDNGPISQPIFWPTGVIRTMSQERLGEVIDDNRDLMGIDSAGPIPSLPFLQFVSEILWRCCYIIESFRTMAPRGGLGLNLLSQPVEGLISFARKGHCYWPWLGPNIALDVFIFEKGILRENDPFKVRTSFLVRMYGMGIRDLKFLLRNPNQPERKEQLDTLHRCHILRAWLGKADSTDLTEQLEFCYYSMAASMRNNEQRRYRPEQETHEQRVKARQREFKILKIMVDRVWLETERNGGHRLTPVLLRRVRAGDGQIREGDWHLLEEEQQRILLGGQTRYHPKHREHDLLLGQWLPRLYARPFFSIRDLYSGLPLRVADTATLERLEEFINIRDGLAYHAPKKLEEFIEIHDYSMLEKPVTSLAIPPDTFAEKPKGAYEQYVDQEIQEAENKTPPREKGYEKDWRDDIFWSDNYIKKTPNTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY74</accession>
    <name>A0ABR1WY74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671009.1">
        <property type="nucleotide sequence ID" value="XM_066807391.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040451"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF5">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="5"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="314" mass="33805" checksum="DEC613DCE4E1CBA3" modified="2025-10-08" version="1">MAPLGVAIIGGGIFVKEEHLPAVLACPQLSLKAIWSRSLKSAQDTANLIPGDASTSVDLYSSDSGDGKSFEDVLKRADITGLIMALPITEQPAYIEKALAAGKHVLAEKPIAKDVETAKQLIAKSQKLSPETKATLSIAENFRFIQGYTYGAEQVKQLGKVTGFVVRVSWSMQTDNKYLNTAWRAKPEKLLGPENAVDSVIAQTSLIQSYLPPVDSINAVLKTKSNVVGSFIFSVGTTLGAFDFLIACEKEKAFEKSNGVKEEVSAWAESMASGTPNPQQAPEMALADLELLEGMLTSGDKEGERQKLDLQHYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYD4</accession>
    <name>A0ABR1WYD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNL zinc finger-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003136</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671069.1">
        <property type="nucleotide sequence ID" value="XM_066807451.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040511"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024158">
        <property type="entry name" value="Mt_import_TIM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007853">
        <property type="entry name" value="Znf_DNL-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922:SF13">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05180">
        <property type="entry name" value="zf-DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51501">
        <property type="entry name" value="ZF_DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNL-type" evidence="6">
        <location>
            <begin position="77"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="156"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="258" mass="28228" checksum="B7F7AF8B5AEBAFD2" modified="2025-10-08" version="1">MASKLRANALQALVRSVRASAISPAPLRLHLRPYPSLPRTLQPAQLSRRYAHAIPKPSRPAPAAASSPSEEIKQRKLQEPHYELTFTCVPCSERSTHTVSKQGYHKGSVLITCPSCRNRHIISDHLNIFGNRKITIEDLMRERGQLVKRGTLGEDGDVEFWEDGTVTERKKETGNENEASSAQGGGVSTSQQSSTVNPAASGPLANSPTRPQLGDAQSSATNTTPSNRREFSTFGRRNRNDGTLVNNLLEITKARALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYU2</accession>
    <name>A0ABR1WYU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Kinesin-like protein KIF22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003254</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671187.1">
        <property type="nucleotide sequence ID" value="XM_066807569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040629"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.280">
        <property type="entry name" value="AF1531-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF9">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="2"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="408"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="599"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="623"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="90"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00045288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="741" mass="81476" checksum="8F58C4F039B06C1E" modified="2025-10-08" version="1">MSVRVVARIRPLLEKELDKDIIVHAASTEDGKPTTLVRIPSPKNGAEEFTFAFNSVYDQQTSQEELFTQEVAPHLKALFQGLDVTLFAYGVTGTGKTHTMRGGMKLAERGVIPRLLSSVFRRSKKIAKDTNGGTQVSVALSYYEIYNDKVFDLLESPEKRTPAGLPLREANGKTHVVGLSERPCEDLKDFEKLYIESNLNRVTASTKLNAHSSRSHAILRVKVTQTTEEGVLESTASAIDLAGSEDNRRTDNGKERLVESAAINKSLFVLSQCIDAISRGDKRIPFRESKMTRILSLGQNNGITVMILNLAPLRSYHLDTLSSLNVSSRAKRIEVREIENEIVYKQVPRTNSGNIQGVARQPLRPIANAANAHNVHTGALAAKEKEKEKAAADKPVKLFNVYTDRSKPPVPAKPTIAMTSPSAVPRPANTAVKRSAVAVSKRPGDSESGIARPSKITRPVFSSLPQPSKPAQPSVPAEPVQPAISAELIEAMVEKKVAEILASRGQQAPAQQEPEISDAVQKRLDALERRIEDGRHDDSKSDGLRFLLMARQHKERGEDASALKMYEMALPFFPGQVKLLAKMDRLRVKLAAKAEGKDSGCDIGLESGGSPIRKKKVHRQTDNEEDYDEASEADDDEEDYSRNRKKNKKVKALKLDLPLDDTLLTPHMQELLDIINSKDLSAIMSLQGFGPKKARDLVDYLSATRDEEAGVITSLDQLRAIPGMGGRAVERAYEGLVADRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYX0</accession>
    <name>A0ABR1WYX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671229.1">
        <property type="nucleotide sequence ID" value="XM_066807611.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040671"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="282" mass="30593" checksum="506536AB59626F4E" modified="2025-10-08" version="1">MHHLVEERALHGEEAIQRVALVDQVLVFFPLFAVAQLEQGRAEDRHLLFVADAAEYAIDGAEAFGGIPAFMARHVVLGDGEIDTPQLGVVVARHYLYAYAHTEFAPSADFIARFRFNMNEEDGEGSCSVLTVLVGGIPLPGRVVAGQVAWLLPIFPLVHKDGLQGVFGVFRQRDGAIVTQDSGIDAREHHYRLRGGDLERVGGRFAFWDSEQVLDPFLGMAKHLCSYVDYVVDLFVVDGFGGAVALGVLLPDIGDAEEVRGGLGCDDLCAATGDEENCIGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0I7</accession>
    <name>A0ABR1X0I7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671758.1">
        <property type="nucleotide sequence ID" value="XM_066808140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041200"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="91" mass="10099" checksum="2E5E774723024294" modified="2025-10-08" version="1">MHRFRLGRGCISGQAQVVRSTGSHINQLLADRGENVVIGAAVADRAHPHHSRSPFSHAAALRLWLCQAMLHSALWRTSAREPLRSPRDVPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X109</accession>
    <name>A0ABR1X109_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Threonine aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004043</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671976.1">
        <property type="nucleotide sequence ID" value="XM_066808358.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041418"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="4">
        <location>
            <begin position="30"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="392" mass="41816" checksum="A79C6572B508F2E6" modified="2025-10-08" version="1">MDQGNSRENGVPAAAKPATWVGHGGAAAFDLRSDTQTTPTAAMLAAISVTTLDDDVYNEDKTTIDLEAHVAALAGKEAALFVLSGTMGNQLALRSLLIQPPHSVLCDHRSHIIRHEAGGVASLSQAMVEAVVPRNGVHLTLEDVKEHACIGDNVHDCPTRVISLENTLGGMIIPLDEVRRISGWAREHGIRMHCDGARLWEVVASGGGSLREFAECFDTVNLCFSKGLGAPVGSIIVGPKDVLKHSRWMRKAIGGGLRQSGVVTAAARVAVDVTFGAGPSGEGGLLKESHVTAKRVEKLWSEMGGKMLYPVHTNMLWLDLESMGCSGDRFTELGAQQGLKLSGNRIITHYQVGEEAIQKLAEVFKQVAAERNAPPKLGPKHANDTGVHVYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1V8</accession>
    <name>A0ABR1X1V8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672303.1">
        <property type="nucleotide sequence ID" value="XM_066808685.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041745"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF246">
        <property type="entry name" value="TRANSMEMBRANE PROLYL 4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="7">
        <location>
            <begin position="70"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="306" mass="33834" checksum="C8B26CCA2A44A778" modified="2025-10-08" version="1">MFSYVVAGVALLLVFYNPLLEYFSAGGPRPHAYLPRPAINESLLAIDAPHDGVPDCAPHSYSIHILSKAPLVIYIENLLSTAERELLLNISGPLFEPSTITNNGAETHHDATIRDSEVALLPRSGGGAGADTVRCIERRALALQGWRDDLWLERLRTQRYGPSQHYAHHFDWGSSALGWGRVSSFMVWVDAARDLEGGGTEFPFLRRRGLKKEWCSWVECATTDGESKGKGEQAKAQGGGADNGEDEEMGLVFKPAPGNAVFWENFRPDGTGRGWEETWHAGLPVRKGFKVGLNIWSWGRLDYQMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X205</accession>
    <name>A0ABR1X205_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672266.1">
        <property type="nucleotide sequence ID" value="XM_066808648.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041708"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="830"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="893"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="750"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="848"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="895"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="938"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1004"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1047" mass="116083" checksum="234F4AB8347661BD" modified="2025-10-08" version="1">MSLAEPSVASTLAVPDQQQPEYVEFLDDEGVPDGTVRCRLQQLQGIAHPNHRMSDAVLQERDRENSSVIQHDHSFVELKSPRNKHVDAHAITRDRRRGHNCKLELSECSACGPRVTGLRGSFSIEQIRNHPTSGQPVSDQSAMGTAVNRRRSARELFEQYGVARPSGWLSDEEDLTLSGDRNASPRRFCRICHVCSARTWSPRSRRQQTSQVLHTEVKSQSHQQSAGSRHTVWYEAQPENHDRTPVQAASSGFRPRHNASEAAQSPPASETNKQSMASVGTEINPLRPHLRADTLRSHPTWSVKQNPFLIADREAKAKASGPGADGNGAKARQSRNVAESAVRHTTRTGASDDEEAGCENPVCRATHEGHRPFRHSVFCALYRSSQDEDVYTSPRGLVGEQSQQTNGAISKSRLAEQPSSAVEALHSRHDTIHRHHSPGFHGPHHIAEHLALAAGHNLRGSQSNSAGKAIGQSVVEETVEGSEVRENRAETTEQYAMKQLEPLTQVQATTKIGSFRYREEPLPHGHPPSEEHRYTSASAETVLDDDISKADSELAEPESEVHETHQTLRHVQRSQHMRRAVGEERPSPVGDNSVPHGTPSSRSPFRVIKRMGSTAFAGQGASSERTMHKEVQYTSRIESTSRGKTLSAALDARSDSDRQSHVSDERIAFNGQERGVAPKSRVASPPPWLKTPSKKPANVQDRLRHVGTRSQYGLSRASREQYRRVDRPNNSTRSHDPSQNTPGRLSSSKFDLRYASKDPQRTVHTQDESDTWLGLPSGLQQQDTASKSSAAQLKHTASQEEAPVPVQRSSSQYEHESGYTESCIFCEAPSPTSPHMRGPHERNAGALSPSVVSSNNPSGKANPRTESVESNYRRATLRAQEELDQLFAETRYSSHRQGTVETRATASGFNATPLRRRQVSFQDEEEAPRVQKSASNYENGSDESFSFSSKGSNPEIHRPTPIAPPNHDCRWKDRYMALTSEIRQLKAEMSTRESFHDVDADSARDQGSQQQDEDLGIQGLTIVMHLKGKDDLVINTDLTQEAEEVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X211</accession>
    <name>A0ABR1X211_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Protein PBN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_004371</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endoplasmic reticulum membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type III membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the PIGX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672304.1">
        <property type="nucleotide sequence ID" value="XM_066808686.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041746"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042322">
        <property type="entry name" value="Pbn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013233">
        <property type="entry name" value="PIG-X/PBN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28533">
        <property type="entry name" value="PROTEIN PBN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28533:SF1">
        <property type="entry name" value="PROTEIN PBN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08320">
        <property type="entry name" value="PIG-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00780">
        <property type="entry name" value="PIG-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 11" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8089410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="501" mass="55829" checksum="65C331F3C7B927B6" modified="2025-10-08" version="1">MRQRTTFFHRNEDAIDPASLQVSGRTLSGPSIKAVREDRFTLGLDELPAELQELLRLSQELYIRWASPVPYQAIGPWSSRLSPGLHVFYTPQADAKANVASDHELCLLLRRLGSVECSTPHKSFSRLPNDRFSHSTALEYYQPVYDLSNFVEYVVQYACAPSDAECKTRFDAVKQASSLDFSYDTISHVVKVTSLWGRQHQPLSISAPASHRVEVGLLTPNEPPHLEQHEIGVTGLLTVLGEDSKPAPTMFTFPSRHKQANTGFSSTFLTPTGLHPTMQLHIDSNQPPMEEDSYCALHALLTLPRTIFADKYQLEDTLFLASKNLTALQYISQPVDLEAPDYVMDIWGSSVLLELSTPVTESKEGFTAEIPLHLRYQSPQHGSESTFEVPYPAVFWACAAEEGTKFPSSPFDRINLGYDGLFGPRTLFWHLDPVAKSGSDQLVIGGKVPVLDLDKSRSINTVTSIVVVVGFAWVVYRLLMVYLRTGYGVAQPVKAAEKKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X315</accession>
    <name>A0ABR1X315_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672680.1">
        <property type="nucleotide sequence ID" value="XM_066809062.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042122"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="103" mass="11450" checksum="22A14F44EE3321B2" modified="2025-10-08" version="1">MRRQPAAKLGVANTEMYRSLRENLRLYYQDRPSVSSLLDAWSSSGGDEDGGERGKPKLTIDATTERLRRAQMLLYRSSGKPATRPPPIIRATPASGPRNIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X436</accession>
    <name>A0ABR1X436_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Guanylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673065.1">
        <property type="nucleotide sequence ID" value="XM_066809447.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042507"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021861">
        <property type="entry name" value="THO_THOC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265:SF0">
        <property type="entry name" value="HPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265">
        <property type="entry name" value="THO COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11957">
        <property type="entry name" value="efThoc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="2">
        <location>
            <begin position="626"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="827"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="867"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="901" mass="99507" checksum="F16E7C24CA89B158" modified="2025-10-08" version="1">MSSSLDIGVPQAAAFSQALQAALLHARQIKTSNTIEPALTRADFNDLFAQLPTIFPVDDAEDASATEGKANDSKTVDPKKKRQYDVVEVVARNQLNALVASTSVDQPEFVDMWNLLDIVTALTDNENCDAALTLSLVEALLDSQTIKDCRITFDYLESRRERLYAVPKHSSSKKLVMLRFCNELLRRLSRAEDIGFCGRVFIFLFQGSPLGDKSGVNLRGEFHTENVTTYEKIPAKAEGATDKMDVDSSAESSKDDKDGKGTGPKAVTFDSRNRTSSEKEKPLDMDTLYPIFWSLQEYFSQPTKLFDTQNFTKFKSALEATIVAFESVTQGQKGLKATDDTKDASKKRKRIEANSIDNSNFNPKYLTSRDLFELEISDLFFRRHILIQAVIVLDFLRSLTAQARTKYANIANPNRSVMYSDKIVSEEDDKWAESIKKRINDYILSGPDGQYVHRIIQSVTSRDKGWTRWKMEGCPPISRSPVSPAEFNEARASAKRMATSKRLRPHPMGSLNLDFLKEEDGETAMAKFKDPARYQLPDLAVFKAKIAEDDLNLEFAKSEKEKKDILEAKASKTWRALRLARRTRLAALDKIDDWQNIDAVFEDPKAATEEPEEEEEGEVGRKPDDKRPIVISGPSGVGKSALVAKLLERQPRVFKKLAIHTTRKPAEGEVNGDDFQFVESGPFNALLDGDKFFSFVTRDGTDYGASRGGVDTIGESGKTPIVQLDQEGVSSVRDNLYDARFVFIAPPSATEAFEARLKASGNYSEDKIPGLLKAAEEEVVQAKAEGDFYQVLVNDDLEETCKALEAFIYGDSYDPAPEVTMTNGVNGEEEEAAPEEEPPATEEQGPEPEPEQGEGDIAMKDNEEDPTAAAAAAVAPPAAADAGADATGEEAQANGATPTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4K7</accession>
    <name>A0ABR1X4K7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_005300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673233.1">
        <property type="nucleotide sequence ID" value="XM_066809615.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042675"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00496">
        <property type="entry name" value="PheRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040586">
        <property type="entry name" value="PheRS_DBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040725">
        <property type="entry name" value="PheRS_DBD3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003210">
        <property type="entry name" value="PRK04172.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF40">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18554">
        <property type="entry name" value="PheRS_DBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18553">
        <property type="entry name" value="PheRS_DBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="232"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8090339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="514" mass="58097" checksum="FE0FA8695370E669" modified="2025-10-08" version="1">MAPAATISTEDLIPEVLQALDKSDQDSISSADAFPAVPFETMKAILDRLTSRSMTTYKQVDTEEAVLEPEAETIVSHGSHEARVFEAVHQAMEGLSIQDLEKAIGDKTVTKMGQGKAFKEKWIKKDGDKLVAITDSITDVTRDQLKVIQETKTHDPKIINELKKRKLIRIQKSFSFRIAKGDKFALEMVKEETDLTAEMLASGSWKTATFKPYNFEALGADQHAGALHPLGKVRGEFRQIFFEMGFKEMPTSQFVESGFWNFDTLFVPQQHPARDLQDTFYISDPKTADRPGPEDENDKRNYAEYFENVREVHENGKYGSIGYRYPWAEDESLRLVLRTHTTSTSASMLYKLASESRNGQSPPVRYFSIDRVFRNESVDATHLCEFHQVEGVIGDYGLTLGGLMEFMQIFFEKMGVTNLKFKPAYNPYTEPSMEIFSYHEGLGKLIEIGNSGMFRPEMLEAMGLPSDYKVYGFGLSLERPTMIKYGISNIRELLGHGVNLNVIEKSAAVRLDKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4S9</accession>
    <name>A0ABR1X4S9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673322.1">
        <property type="nucleotide sequence ID" value="XM_066809704.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042764"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF15">
        <property type="entry name" value="ACID PHOSPHATASE PHOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045045321" evidence="2">
        <location>
            <begin position="20"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="406" mass="45113" checksum="C5BBD405EC70C8B8" modified="2025-10-08" version="1">MRSAVLSLPLLTVGAAAQAENMYTATATSDVYAARATAKTLSNTSNVKGKAFDRFAVIWLENTDYDMAYGDENLNWLAKKGITLSGYHAVTHPSEPNYVSAIGGDYFGMQNDDFNQIAQNVSTVIDLLEDKGISWAEYQEDMPFSGFSGMEWLNQENGKNDYVRKHNPAVIYNSAAGQIDRLASMKNLTMFYEDLKNDALPQWMFITPNMTSDAHDSDIQTAGAWTRNFLEPLLDDERFMKNTLVLVTFDENDTYQVQNRILGILLGDAVPAELVGTTDGNFYNHYSEIATVEANWDLHTLGRFDVGANVFKLVADKTGDTIRAWSGEVELSQRYFNYSYAGAFNTNGGNRRYPAPNLSGDGTTHNRTVLPGIQELWKDSPAPVYYTTGLEIPDGLHPPSGYEPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7F7</accession>
    <name>A0ABR1X7F7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001808</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673419.1">
        <property type="nucleotide sequence ID" value="XM_066806123.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039183"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11051">
        <property type="entry name" value="CYP59-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF222">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE STCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8091447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="533" mass="60360" checksum="69A8C1CD76184D1D" modified="2025-10-08" version="1">MAQLSVAVAIAAVTALMTVFITKFVSNRQHVRKLQAAQVPMPPFHPVFGHFIAVKKAMQGLPLDVTMHVMVQKMARSFPSGIFYLNLWPFSKTLLVNASPVAAAQVEAAFLDKPAPMCKTMEVINGGPSLMTMHGETWKKWRALFNPGFAPAYMAGFAPSIVEEVAVLCQLLRERADQGKVFQLEEYTLKLTFDVISRISFGARIHYQTQGSILADGLRRLVYWTPYGTSFNPVRRYLSPRPLVQWYNSYCIDRYLSKQVDERFEELADSRRDAKDVKSQSRSVISLAMDQYLAEAGETEQLFKATFKRLVIPQLRMFLYAGHDTTSSTLLYCYYLLSTHPEELKKVRTEHDKVFGTNISHEHLYEIIAEDPALLNQIPYTLAVIKEVLRFLRAGRPGLVLTDENGGQYPTEDCQIWTLTLAMHHREQVFVRAQEFLPSRWLVGPDDALHPAKGSWRPFEWGSRACIGQTLAQLELKVALVMTLRMFDIAPAYEEWDAMHPKKGRGGVMSVEGNRVYQAEMGGAGHIRSMDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7S2</accession>
    <name>A0ABR1X7S2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Calponin homology domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001885</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673496.1">
        <property type="nucleotide sequence ID" value="XM_066806200.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039260"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004953">
        <property type="entry name" value="EB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036133">
        <property type="entry name" value="EB1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027328">
        <property type="entry name" value="MAPRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10623">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03271">
        <property type="entry name" value="EB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140612">
        <property type="entry name" value="EB1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51230">
        <property type="entry name" value="EB1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EB1 C-terminal" evidence="7">
        <location>
            <begin position="178"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="139"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="143"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="268" mass="29563" checksum="01F9BD1E2BD63134" modified="2025-10-08" version="1">MAQQPAPAEHDQGRAVRYWVSPTTPFISSLLAAPPPQHRFRSQVNRRSSPSSAALCQVFDSIFLDIPMSRVKFNVNAEYAYLQNFKVLQNCFAKHQVDKIVPVQQLVKCKMQDNLEFLQWSKRFWDQYYPGGDYDAVARRKGSGAPPSSGPGPKAAPNTAARRGGTTPSGGPRLGARSAGGGGAASAALQAENTTLKETVVGLERERDFYFSKLRDIELLVQQAVEEDPEIEKQEDGLVKQIQAILYSTEEGFEIPAEGEALDDQETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X840</accession>
    <name>A0ABR1X840_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673551.1">
        <property type="nucleotide sequence ID" value="XM_066806255.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039315"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="16380" checksum="D3FBAD1E65F38FE4" modified="2025-10-08" version="1">MEDSKSSVSVHVKLTVNPSKTEDFLSALKVIFEKTKLEPLNTFLEIYRDEQSPGMFKLVENWNATADYMMNVSIYVSICVLFLRGMTGADNNPHQVQVKKDYYQAYYAALQPILLKAPEVEIFSRMPDNEWVSVRKECYPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X842</accession>
    <name>A0ABR1X842_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_001944</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673555.1">
        <property type="nucleotide sequence ID" value="XM_066806259.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039319"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8091583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="529" mass="59651" checksum="C766D29D8B400E09" modified="2025-10-08" version="1">METFSNVSQAGGFNRPLQTTIDFSKEVFGQVTWQQIAAAVAVYVFSLAFYRLYLHPLSDYPGPKLAAVTRWYEAYYDLVLGGQYTFRIAEMHKQYGPIIRISPYELHVSDPAFFEKLFRQDGRWDKYAWSYDAFGAPLTAVATSAHDLHRRRRAPVNSFFSKQNVTKRIDTVKRQVDKFCARLDGFTGSEDRLNLNIALAAFARDAASDFMLGKCYGNLDQPDFNAGMTKAIGGLTQMWMVTKHFRWVGGTLMALPVPVAKKLGGEGNRTLFSYLDNTLHDTAKLMTQAKSENPDPDAPHTLVHAIVQSNLPEPELRHRRVAEEVASITGAGFESTAAVMRQPGDPRPSAQRAALLGLRQQGAYPADLNWTRLQQLPYLTGVLHEGLRLSPGLASRMARVAPDRDLFYGERWRIPAGTPVGMTTILMHYDEQLYPEPKRFVPERWTDVEKRKKAEKTYAPFSRGTRSCLGMHLAWSELYIVIASVVLRFDLKFDGAGPKDWEPAVDQFTIGTKDQSGIQTWVARYEESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X864</accession>
    <name>A0ABR1X864_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673619.1">
        <property type="nucleotide sequence ID" value="XM_066806323.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039383"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="53833" checksum="DF9DC3B5F03E3B8E" modified="2025-10-08" version="1">MADQTQAQDRAVALTGWRVKIPPPFSSPAPITIVARERCQTLWNNFVEDGSSTSNPRAWRSAATALTGEETGALSSDEATRSYKLIGFVYPRLDIDIANKEPDNMDNTTIISNNSNNKSERPSIPAELGLVVAALDDIRKTWCQVYLLLDMKNGLCTPYGCDPRVVFYLPRFRVNIDETSLPRRDNQKAGSRLWDIFLSYDDSDSDSDDYDYDENGIEVIRGCSRRDSNEKSPLLVRVEEIPYGDVPLSVGVEKPTSKAKVVHFDDNESSSDEGMSIPNTMDIDESSDEESSLFVSSGESADEEEELMELVRDPSEEAQVQTPNPNDMGDSDTSPASIPSFTDQLCRMTALCKTTEEIQSIDRTLRLELVWNLPQAAQERSAMRKFVDLSKDWERNDSHAFCVEMSACGQLEKAPRMSEVTRIRIALAALKADLGYEWLGRFFKFTTVLLKDEQKKPIPQDTVNYAVLKSLELVATLTQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8M7</accession>
    <name>A0ABR1X8M7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673789.1">
        <property type="nucleotide sequence ID" value="XM_066806493.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039553"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025975">
        <property type="entry name" value="Polysacc_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14099">
        <property type="entry name" value="Polysacc_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047089488" evidence="1">
        <location>
            <begin position="21"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="250" mass="27525" checksum="0E15DD81F7D93F27" modified="2025-10-08" version="1">MVHLAHLAATALLCASYACAALLVDYSAARGDEVAKMGLVNLEAARGEKQHGNTADLYIKNDKDWKGAKSAHFHRKKDDIRAEYHALNKKTQEGKTYFIGYQFALGATPDALMVMQWKEFVANGAAGSDAANIPLSLEVRQNALHLQYSAQQSSGRKPQWSTPVQPKTVYTVALEILARDGGKGHVRMWWGGKPVTFDTTKSTTLMGNLFPGRSDPKFGIYRGEEVVTDSWVYQVQIGESKADLDSKFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8Q6</accession>
    <name>A0ABR1X8Q6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002121</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673732.1">
        <property type="nucleotide sequence ID" value="XM_066806436.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039496"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047167955" description="FAD-binding PCMH-type domain-containing protein" evidence="5">
        <location>
            <begin position="20"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="62"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8091760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="508" mass="55852" checksum="4C51B21EB964C075" modified="2025-10-08" version="1">MARIGALAIAVAVLATAETAVNPVATTCCNALSRNPVLHDKVLYPNSSAYEDRIKDYYAANAALRPWCMVLPLTSEETSETMRVITANKCPFGMRGGGHMVFAGSSSTDHGVTIDLGYMNYTTYDPRTKLAYVRPGGTWSEVYGTLGPHNVTVTGARSNLVGVGGFLLGGGNSLHAAAYGWACQNVENFKVVLANGSIINANRSHNPDLWLGLRGGSANLGLVTRFDMRTIPEPLTWGGGRFWAYNMSDAVVEATVKFTDTIEEHVDCSVEAMFGWDPTNTQQPGGMYAVASLDNVRNEAYPKGLRDFLVIGGVYDDFLESRTVLDRTTLGNGVDGLQDVWVTGSYNNDIRILRYGLKRFEELVQQLKDQIGYENDERLGALLQYQPLTEPMIRNGDGPSVLGLENYFVKAGKNSAGMLSTVLLQAAKPAHLAALERIGHEFQRDMDEHATELGVNWGWKYLNYADYSEGPIARYGEESVEFLRKVAKRYDPYGVFQNLRQTGFKIPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA07</accession>
    <name>A0ABR1XA07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-binding oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000092</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674180.1">
        <property type="nucleotide sequence ID" value="XM_066804407.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037467"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF13">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="49"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="464" mass="50392" checksum="5430968D43CBCA84" modified="2025-10-08" version="1">MDKLSNAVQLVLGLGSLNSSSAVGSPSALSACQQLGATFNNNATFSQTAWDQPTCIFLPETTAQMQTAIPLIVGHQSKFAVRSGGHMAAKGVASTDDGVLVDLSRLRRLEYHAEAKEVVLGPGLRWRDVYDYLDTYKVTVVVLADGSLVNANAVSRPDLYRALKGGSNNFGVVTAYTLSTYSINDAWGGTKVFSWDKTGAVLDAITAYQHLPDKDPYANMNLNAAATNQTGLGVILTLVYLKPVEKPEIFSDFYKIEALMDTTGLKTPTNIMGEFPTPAVPRVKHWTTTHKATKSMQKAIEHIMATTPHLATIKSVPTGTGVFSWQPIAPSLVEAGRRNNNDDGHALSLEPVAQNRFHLDVLWASAADDDKIGRAAQAIVDEVEGAARREGSYLPYLFMNDAPEGAPVIASYGVENVRQLWEVSERYDPDQVFQKLLPGSFKLPPSGWDQSNPWGPQKGRRRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAK0</accession>
    <name>A0ABR1XAK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000385</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the secreted LysM effector family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674473.1">
        <property type="nucleotide sequence ID" value="XM_066804700.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037760"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045162183" description="LysM domain-containing protein" evidence="5">
        <location>
            <begin position="23"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="277"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="365"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="598"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="679"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="513"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="654"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="514"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="554"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="565"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="729" mass="76691" checksum="AD8CF51191CBCE51" modified="2025-10-08" version="1">MVALRRCVAGLGALLSFSPVLAIKMLYEDSIPEHLPSVCSAALMADVACDFLVPNLRPDFFYPPASLNRACTAGCAAALASWESSVRSACGKDVVIPAEFDLLASPIVIPATRQYIYSFTCLKENNVFCGPVAALASFFSDPGVSIFNYINELPEGATKPGDCDPCLAARLRMRSGSPYFDGPVVASESLYQSMTSSCGITGKPATTSTIDYFTSQPQPTEAACSGTIYQIQGGDDCYGISKAQSVGTAWMLADNNLGAYCAEFPTSGSLCITNTCKTVTVAKNTTCSAIAASAGISEMQLLAWNPVINPVCSNIDMMNGTTLCIEPPGPKLPPAATTDIPPSTPTTAAPIPTNTAEGSDKPCGRWYEVEPGDYCNLVTLKFAISLPDFLFLNTGINANCTNLYAAESYCCHLHRRPIHDAPQCHHDTLPEALSICPLASGARDDCVYNFKADEYQFSAEQLGFWKSNCELAATLYNVDFDSFAAWNSLSTNVTDPACAFEVGKRYCGAWALQPTPTGTEAPTPTGTDAGDGKPQPPAPTHSGQPADCDGWHVVSSSDSEGQGISTSSSSATATSSATTTKPTPPAPTHSGQPANCNKWDVVQSGDSCGSLAADNGISVDQFYAWNPAVSKDCVTNFWLGQAYCVGVSSSSSVTTTTTTTSQPTPPAPTHTGQPANCNKWDVVQSGDTCSSLASDNGISLDQFYNWNPAAYCVGVSSSSGRVRRGQSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAM4</accession>
    <name>A0ABR1XAM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674479.1">
        <property type="nucleotide sequence ID" value="XM_066804706.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037766"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="74" mass="8142" checksum="50C851B6F2AECE3C" modified="2025-10-08" version="1">MKSNDLFWTEDGYMGLATHGVQPGDIVCVLTGLCIPVVLRPKDGRFMLVGECYCFGLMHSEDTTGGDLEVFEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAU4</accession>
    <name>A0ABR1XAU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674500.1">
        <property type="nucleotide sequence ID" value="XM_066804727.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037787"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="475" mass="52042" checksum="5D523ED1D92D6A57" modified="2025-10-08" version="1">MADPLSLVGGIAAGLQLVMVASEALLATIKLIKDLKDVPGRLATLLNEVTDSISRLCYSCSTGSNLFRHMNSSQMDRLARCAAALHSALQDISSVLVPLVDSEDGTGRVRPSRYFWKRLVSLKIEKELPEKLNRLNRLNIEIVRELGVATLETQITTKGLVAASNFTSRQGLRSIESKMDTLQDDFRDFTRSVQRVHLVTSEVSHQATIAPGDSSASSRVEVSQSSYKPRNNPTSSRIGPGGTESYTQESIEDPRLPPDQAIQILRYLSGGSNAPTTAGLRVISPNGLSSTNLEAVLCGIRTYYTIGNFDASPMVVRTTFWEDTDLAIYLMKVSAGVQRGASQSQTRGFRLLKKSTAEVPGTLYQGEASLIIEALSILSPTNTKTCAYVRDGMLRYLSELARQQLPSTHPFVLVIDTLRKDDNCQDVTLRALTFVAERLRESLGPVHQLSQMATYRLCGLFAAQRAVCRGPKDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC61</accession>
    <name>A0ABR1XC61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000915</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675003.1">
        <property type="nucleotide sequence ID" value="XM_066805230.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038290"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045323992" description="Apple domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="3">
        <location>
            <begin position="170"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="586" mass="60966" checksum="356C8CC9B816D0DA" modified="2025-10-08" version="1">MKDSAPVHFLKWLAVGCCVITAVVAQSSVTCPANNGDLVVKGNKQYELQCGQTVKGAPFKTVPCSDALVCAENCANDTACVHSTFNSATNECLLKTNDVTGRPHAAQWTWRYVGPAPPSNPPAQQPLGGNTGTAPGTGSGSGSGAMAANCPADDGKTYTTPNGITYQLKCDHNMAQAGALRSLAVSSLQQCADTCSQDPQCVAMDFIASNNNCYLKTATGPLVAQVGVHSWIPQTCPSPRPMVANTNPAIININTDLICPQNDGKIFEAADGTWYYLQCCTDTSGAVAIDAVAATSHADCIEKCAADKKCKSATYATWGQTNCKLYGYNQFSTTHIAQIHHAFVTDPPTTAPLASDAKMCSTECPYAHGQLFVSPTGENFQMTCDKRHGTTVLRKERHKTFSACMAACAAMPACHSVDYEGRTLNCYLTNNVHQPGIAATAFASAHSLGCAGACSSCKGGCDDLTSGGAGNATAADCPADDGKIITSNAEDFRIMCGVCALSHGNTLGKTAAGTDPQTLAECAEACAKEPSCASANLLIDTATNALVCPMHKAIQANGVDLTELKHGPCYVLVKQSGGMVSYAITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC94</accession>
    <name>A0ABR1XC94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein 53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000969</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus outer membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TMEM53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675057.1">
        <property type="nucleotide sequence ID" value="XM_066805284.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038344"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008547">
        <property type="entry name" value="DUF829_TMEM53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265:SF30">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05705">
        <property type="entry name" value="DUF829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="33855" checksum="789F3F41B9686678" modified="2025-10-08" version="1">MASPQTGPIVPDPLASISMTKLSTYVSFYEPAAASDSQQASSATATDSQTPKLILIASWMGAQDMHIAKYVTRYQKLYPTSRILLVKFVCKLIIVESLANDAVHPAVAYLRSQLDSDYLAASPVRPQILMHVFSNGGMASTKHLLGLYRKETGQTFPLHCAIYDSCPGLWTYIGVMAGVPKGMWRWIISPFLHVLNFYFMIVVKVLRRPYNLAINANFHNNKEEVHQSHRAYIYGKKDKMVEWTHVERHAQQAKDQGYSVRTELFANSPHVAHMRTDETRYLRIIKETWEEAARKYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDQ6</accession>
    <name>A0ABR1XDQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675502.1">
        <property type="nucleotide sequence ID" value="XM_066805729.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038789"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF267">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G06860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="76"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="311" mass="33970" checksum="0A0D3694A6E90A82" modified="2025-10-08" version="1">MGKSRLRGSSPTYLTPSPRATSPSSVYEDWDTETAMSTSRPASLAIPRTGSPAARLPSLSEILNNTAAPPWTLSAFTAYLSQNHCLETLEFLIEAERYSATYVHLVDSQQHMSQEQIDTLCSAWDRMMQTYITPYGSREVNLPAPVRDRLLALSQSLPKPPTPSELNEAVSIVEELMSDSVLVPFCQSVTMAVAEQQQQSADESREGRHSRSRLRVPKESFSPDESSHSPKNTFLPLLTLARNSMHNRSSSIIAAETADADLITDDSSSPNSTPGAEPVTPPTTPPTSDFAFSTSPNGLQRAITGNSWGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDS2</accession>
    <name>A0ABR1XDS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sister chromatid cohesion protein Ctf8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CTF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675608.1">
        <property type="nucleotide sequence ID" value="XM_066805835.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038895"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018607">
        <property type="entry name" value="Ctf8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28605:SF1">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28605">
        <property type="entry name" value="CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09696">
        <property type="entry name" value="Ctf8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="17848" checksum="BAF5F19140943863" modified="2025-10-08" version="1">MASVQLHPRRPASTEAAAVANPLPPLIQTPSGLALLELQGTINLPYHTGAEDDNNNAPEIPIGRIWFPDYNPNALDPKSTAWMKRVHMYVGQHQRMTGEVKKLPRAMAVIRKRAPGATAGDTEMTDDAATTPANPDGSSTEDLEVVEIIKYKLVFSSRPEPVGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQJ7</accession>
    <name>A0ABR1UQJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MICOS complex subunit MIC10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_015419</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Mitochondrion inner membrane</location>
            <topology evidence="2 9">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the MICOS complex subunit Mic10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660618.1">
        <property type="nucleotide sequence ID" value="XM_066819733.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052793"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007512">
        <property type="entry name" value="Mic10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304:SF0">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04418">
        <property type="entry name" value="DUF543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8061198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="104" mass="11252" checksum="8801A90319174299" modified="2025-10-08" version="1">MSDTSVPRPSSAVSRPVSEALLNEKLELLLTKCLSTPIVGSLPLNMLIKSTLGLGFGVVFSVLLFKRRAWPAFVGVGFGAGRAYEECNWSLKQASRDLKRTTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT14</accession>
    <name>A0ABR1UT14_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin-related protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660678.1">
        <property type="nucleotide sequence ID" value="XM_066818490.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051550"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10210">
        <property type="entry name" value="ASKHA_NBD_Arp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="451" mass="50165" checksum="ED464270A11FFF1A" modified="2025-10-08" version="1">MAPRKSKTSRPAPPSRTLVLDNGAHTLKAGYVTDDDATTDETPTIIPNCIARDADRRVYVGHELDQCKDFSEIAFRRPVEKGFVVSWEAQKEIWDRQFFDANAPQGPCDPSDTRLVLAEHSNSLPVLQSNCDQMIFEEYGFASYYRANGPSLNAYHDVQAIFRTPRDPATVAQLPAECLLLIDTGYSNTTVTPLLQGRPLHSAVRRLDVGGKLLTNYLARLISLRHYDMRNEPHIVNEMKEQACYVSLDFHADLEKAWKGTRGEKREDYLTGGGIAKEYVLPDFHTRSKGIVRDFDPEQAGRTRKLAKLGEATEDVLTLRNERFSVPELLFHPADIGLHQSGLANLVWESLLAVPTGLWPALLANVCVVGGNALFDGFIQRLQKEIVKLVPDDCIVRVARPANPITGTWVGGAKLARRTEEMAGLCVTKAEYEEFGGAWVARRFATGGNDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU09</accession>
    <name>A0ABR1UU09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-lysine N-methyltransferase EFM2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661014.1">
        <property type="nucleotide sequence ID" value="XM_066818826.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051886"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="355" mass="38706" checksum="698E95FF2029B8CD" modified="2025-10-08" version="1">MGAAALPLPPTGSLPPLCRPDTFTEDQEKKNPLPVAPTPPVDSGYVSETENEDAENVKQALEELRCDAFERDFAIRWLTSFVSRAEEMILIPEEARQLATDKAYCILESFMSAPDEEEHEDEGIVRDFAFTLRSSAPSPVTGSCENELRGLHHPARTHVRLPGAVRTRGPRQEGGAAHRRARRGNGTRGTRHGPHAAASRRPAADPLIATDFHPVVLENLRANIASNFPGVENPPVDACHLDWSAPSRAPPLDLPADMLVATDVIYAPEHAVWLRDCASQLLAPDGIFWVLIAVRTNGKFEGISDTVEAAFGAPECPKDAEGRKLSILNIETLAKPDGLGRGDESGYKLFHIGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUI8</accession>
    <name>A0ABR1UUI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661181.1">
        <property type="nucleotide sequence ID" value="XM_066818993.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052053"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="248" mass="28829" checksum="610766073419743C" modified="2025-10-08" version="1">MGEKGLQETLYPGTPESQYGPPRKELPRRDEDGYRWSDKDPQHTSPIFSTDREPSSRPTGCPCPDDAYKEELTNLIRDSDDYAIAFARGDDRYLGTVFGQADRRMDWMFQAPETLTKLGVIHSRSHGWRPRCPAEALEFMRYLANRATLEFDQVRRDDPGPRLRRDLLDRLEMAIKAMRQAFEECAEYALFEREQGWLYEKSYGDLWAAEWRFTKNAEPVSLAPIPRGTLERNQRGRPIYSRSVNING</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXX5</accession>
    <name>A0ABR1UXX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661500.1">
        <property type="nucleotide sequence ID" value="XM_066819312.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052372"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="125"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="34293" checksum="1C5142A6DB1E7F53" modified="2025-10-08" version="1">MSRIVIRNVRVFDGEAFVGPQTVVIEGSHIGQARDPADGDEIIDGTGRTVLPGLIDCHVHIADEAQLASCASFGVTTGSTHARLFRFAGVGGDQAVHDVEEAAEFVRDRVERDRVDYVKVIADVPGHDQAVLDRICAEARRRGKMTVAHAAHFDAFPRCLRAGFDVVTHVPLDEPLMRDVAESMAVRGMVAVPTLTMMESFARSWVMWLLARRTMDFEHSLCSVHAMKEAGVPILAGTDSHSAGVLYEIPAGKSLHHELELLVRAGLTTEETLRAATSRAARCFSLEDRGGLNRDYGRISCWWRGIHSRIYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYI4</accession>
    <name>A0ABR1UYI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_014935</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661437.1">
        <property type="nucleotide sequence ID" value="XM_066819249.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052309"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046184458" description="Peptidase M14 domain-containing protein" evidence="9">
        <location>
            <begin position="22"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="10">
        <location>
            <begin position="76"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8062838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="448" mass="47928" checksum="63B0E6FC02E900F3" modified="2025-10-08" version="1">MKFCSLAALVGLLALSTTSSACLLPEERENDGHIRAIRGRQSRNNGTPIGTGDRFNRGTVAPRGLGSQGSSTSFSTILNVNEIASGLKGLASTYGIETFTTPYKTYQGASIQGAIVGGSGGRCKDAYRVFLNGNIHARERGSADNVLFFISDLLYANKTNAGLTYGSKTYTAGQVKTALSAGIVFIPLSNPDGVAYDQSSNSCWRKNRNPASGTGSASGIDLNRNFDFLWDFTKKFASSVRSSVASTNPSSETYHGTSAFSEPETRGIKWVLDTYTKVRWFVDLHSYAGDVLYSWGSDENQSKYPSMNFRNSSFDSVRGILSDTPGTRGGYGEYIPAEELTTQTTAASRMVSGLTGGGGSQYTAIQSSDLYPTSGASDDWAYSRHFADPSLNLVHSYTIEFGFGNNAASCPFYPTVAQYNANMRSVGAGFMELLLAAVELGLGDKTTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2Y3</accession>
    <name>A0ABR1V2Y3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012295</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="3 8"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662301.1">
        <property type="nucleotide sequence ID" value="XM_066816609.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049669"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046616748" description="Mannan endo-1,6-alpha-mannosidase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8065548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="426" mass="46294" checksum="3104D2278244A152" modified="2025-10-08" version="1">MGKIARIGLAAALASTSTAYTLAADNDITIKDTASQIAKGLFDAYYDPAATTGQFKQTHDWFWWLSGTAWNGLLDYTLLTNDTTYKQPFLDALAKNVGENYDFVPASQVNWEANDDQAYWVYNALTAMEYNFDPLPCPSGGSSSPCETAWVKLSSNAFDRFVSRWAADAGTCNGGLKWQFNPASKGYDYKNSVTNGGFFQTAARLARYTGDQKYADWANKVWDWSTGVGFVSADFHVVDGAGDGGSDNCTKKDKNEWTYNSATYMMGAANMFAYTNGDKVWEERVQGLVNTAKTQFFTEDGIMREACEASNKCNTDNTSFKSSLARWMGRTAVLVPSVRQTITDLLEKSATAAAKTCSGSTCGNLWTASSPGAGKQDFGTQLSALEIVQSLLVLDAPLKLATAQGAQAPEPAQPRIKFSMSVHKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3S1</accession>
    <name>A0ABR1V3S1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ran-specific GTPase-activating protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662587.1">
        <property type="nucleotide sequence ID" value="XM_066816895.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049955"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13179">
        <property type="entry name" value="RanBD_RanBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045256">
        <property type="entry name" value="RanBP1_RanBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF87">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE RANBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="85"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="243" mass="26901" checksum="A9CB9B16FE1E8FC3" modified="2025-10-08" version="1">MSSTDATEPKVEETKPAETTTTEETKPAVTSSSVFSMFGGGAKKEKKDDDEDRGDNSGSAKAQRDAAAAAKGDDEEEAPESEDIHFEPVVKLTEKVETKTNEESEEQMFKMRAKLFKFVRETTEWKERGTGDVRLLKHKENGKTRLVMRRDKTLKVCANHYIVPDMKLSPNVGSDRSWVWNAAADVSEGEPEAVTLAIRFANSENANQFKDSFLEAQKANEALFTAAEGEGSEEKKEPVPESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4R3</accession>
    <name>A0ABR1V4R3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662655.1">
        <property type="nucleotide sequence ID" value="XM_066816963.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050023"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="121" mass="12531" checksum="33E6BACD98347975" modified="2025-10-08" version="1">MEDAVVLPEVLEACDLLVEVLERAVVLEVHTAETLLVQLLHADLDVGALALESLELGLGTGFLLLESSVSLSASVSLQSTSSKPGVSIRWDGHVGPKDATPGSPAPAACTTGGRGQYEPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4T0</accession>
    <name>A0ABR1V4T0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-xylanase</fullName>
            <ecNumber evidence="6">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011821</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661828.1">
        <property type="nucleotide sequence ID" value="XM_066816136.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049196"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF76">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH10" evidence="8">
        <location>
            <begin position="130"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="59"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="414" mass="44999" checksum="C9FFA1BF9E9D6399" modified="2025-10-08" version="1">MGQLVAVGPTIIAGYGSWGCSLRAAGKRATEPGLYSTVADQPPRLLTFLPPWAPWPALASTSPALQRPSSPPPPPPVTPSPPPCGDHHLHRPHDRRVVGRPLGHPSKAPGPNAGLDELFKAKGKKYVGTSADQFSLNNANVAKLVASDFGQVTPENSMKWDAIEPRKDGFNFGGADYLVKYAKDNNKIVRGHTLLWYQQLPQWVKDITDKAELTKVLQNHIAKVVGRYKGQIYAWDVVNEIFEESGELRDMVFTRVLGEDFVRIAFEAAKAADPAAKLYINEYHLESASGTKVTGLNNYVKKWIAAGIPIDGVGLQGHLGGANPTAAEMKAGMELLSKSGVTELAITELDILNAPADEFVKVFEACLDIEMCVGITTWGVSDANSWLPNDSPLLFDKQYQQKAAYKAVHDLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4Z3</accession>
    <name>A0ABR1V4Z3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prefoldin subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663001.1">
        <property type="nucleotide sequence ID" value="XM_066817309.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050369"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23156">
        <property type="entry name" value="Prefoldin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016655">
        <property type="entry name" value="PFD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016396">
        <property type="entry name" value="Prefoldin_subunit_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="136"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="200" mass="22671" checksum="839E9C39425D68F8" modified="2025-10-08" version="1">MSATGKDAVSSKEAGATNPRGIPQAPFVDKVEDYVSSREEVEGTLRNFQEMISKYQFMELNLQRRVAGLNDKMPDIQKTLETVRFLKTRTEDSDPIETTFELNDTLYAKAKVPPSDEVYLWLGANVMLSYPIDEAEELLKSKLAAAKQSYANCEEDLDFLREQITTMEVAVARVYNWDVVQKRKEKADEEGKGKGDEEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V518</accession>
    <name>A0ABR1V518_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663047.1">
        <property type="nucleotide sequence ID" value="XM_066817355.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050415"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="224" mass="24695" checksum="951ADBE1D72BB108" modified="2025-10-08" version="1">MGILRATFKTGLYGITGGLASVGAGMAYLGATTSIVDLKNEDAWFRSKTYAKYNPKANPALQDDCIKRVPLSKIRPELRNDEAALTLEFCRFWPQSKLHERYDAPPGSEGHTWETSELAVAKYEPGLKFVNHFEVVENQGNEITVRCGGSPLQPGLRNSDGLILFSARIDREKQEAVFSLKSALFDSAGSYGKGAGHPIPPKIVFLHPWYVRILTHCGVENVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5A5</accession>
    <name>A0ABR1V5A5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein kinase gsk3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_013123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663129.1">
        <property type="nucleotide sequence ID" value="XM_066817437.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050497"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14137">
        <property type="entry name" value="STKc_GSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039192">
        <property type="entry name" value="STKc_GSK3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="36"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="395" mass="44910" checksum="6DB4F673B30C22A2" modified="2025-10-08" version="1">MSANRPNAAFNSLRMGEIIREKVQDGITGETRDLQYTQCKIVGNGSFGVVFQTKLSPSGEDAAIKRVLQDKRFKNRELQIMRIVRHPNIVQLKAFYYSNGERKDEVYLNLVQEFVPETVYRASRFFNKMKSTMPILEVKLYIYQLFRALAYIHSQGICHRDIKPQNLLLDPSTGILKLCDFGSAKILVENEPNVSYICSRYYRAPELIFGATNYTTKIDVWSTGCVMAELMLGQPLFPGESGIDQLVEIIKVLGTPTREQIRTMNPNYMEHKFPQIKPHPFSKVFRKADANALDLIAKLLEYTPTERLGAIDAMVHPFFDELRDPNTKLPDSRHSTGVLKDLPALFNFTRHELSIAPSLNHKLVPTHLQASLAANGLDIDNFTPIPKSEMMAKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5D1</accession>
    <name>A0ABR1V5D1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pisatin demethylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012859</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662865.1">
        <property type="nucleotide sequence ID" value="XM_066817173.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050233"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF236">
        <property type="entry name" value="PISATIN DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="50485" checksum="51A3A42713C3EBB5" modified="2025-10-08" version="1">MGIAADLYDFRWFIALAALAAYLLQKTRAYYRLRSFQGPWSTGWSDLWHSWAILSLKSHLKYDEACRKYGKENVGLEESIDVHVAEFVQLFRSSYISTDTMAKPVDFAKKVQYLSLDVISDISWGKPFGNLKGDRDVDGIAHSSEEGMWFFNFMLATGLYRILHQPLIAPYVGVSVKDATGFGRLLYNARDIIHERLQRDAAHEKRSDMIASFFRHGLSEDQILSETTLQMVAGADTTASSIATTLLYLMTHPRVYEKLQCEIDDASNRVSSTDDGRVISDADARKLPYLQAVIKESMRIHAPVTNASPKRVPDGGDTVVIDGRSIFIPGGTNISYAVWTHRLNRRIFGEDAASFRPERWLLEKDEERLADMNRVHELGFGHGRYQCLGKFIASMEIGKTIFEMMRNFDWSLARPDQPWTEGSYGGILAHKDMWVLVSERKGLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5R5</accession>
    <name>A0ABR1V5R5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mRNA export factor GLE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleoporin GLE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_012378</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662384.1">
        <property type="nucleotide sequence ID" value="XM_066816692.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049752"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012476">
        <property type="entry name" value="GLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960">
        <property type="entry name" value="GLE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960:SF0">
        <property type="entry name" value="MRNA EXPORT FACTOR GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07817">
        <property type="entry name" value="GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="62"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="62"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="177"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8065631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="543" mass="59778" checksum="9E5EBA6B7DE82130" modified="2025-10-08" version="1">MAGSSPVRHRQTPSRPSPVRSPDSSYRSEDRNGEMNHLEALLAAQILHDDVRKRAYKTLADHEYEEEQKKRAEREQEIKDQQRREEERLRHEKKLRDEEERLRALQAQTVPKLPPQPKPSPQSTTVAPSNGDAAAATQPAAAKPTPTPDTSSSGPAAQDPSKNPFQAEPPKTNGHVSSAAPPNTTSSPFARPATSQPANPSAAATAPEPAAQAPAQIQPTRPPAVPVVDDYVQIHKNLKKLRALMTEHAKSNPQLKKQMGEMRREIRKSLGQLTGGKGANKKQLESIKTILMSALHSQPSSPMTDPSSFVVGNREPVEGALNNEPQLPSLFLYLMNQLGKAIINQFINECGASPRSADPVGVVTAQLFSAKEFLWRGQSLIDILMAKFRIVCPVVFGYRGSDKTNQGRLRLGWKKEGDAWISEQQHNDRMMGLGIGYASIALRDFSKSSNINPWPPSRYWKSMADIVNTPPDEMTDTQCIVLKSMLNQHEEKFINFYGSAAVAALRRALVEFPNSAPKKTPGVMGLQVLAVMCKRDMGLDLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5U6</accession>
    <name>A0ABR1V5U6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Mitochondrial chaperone BCS1-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_012408</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662414.1">
        <property type="nucleotide sequence ID" value="XM_066816722.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049782"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="BCS1 N-terminal" evidence="16">
        <location>
            <begin position="65"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="307"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="360"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="505"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8065661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="606" mass="66506" checksum="74588DED134A24A3" modified="2025-10-08" version="1">MDIQSLIRGVLPTMDANATATAAAGNASSSTQHFQLESLLPMLGLRSLLPMYGLVGTWLGIDPTFILTAFGAVWALNKVARQIYGTAFAVTSEYLMSTIHISSNDDMYMHLMRWLAAQPKMTSSRSLTAETVSKTAWEDEDDSNVSRDKSGVYLNFSNQEAKAPPRFVPAVGLHSFWWGGTYFRLHRKQESVFDDGASSGFSTFKDREDLVISCLGRNPEPIKSLLKHVKESYYNNHHARTIVKRPSPMNLRRYGGRHCWQQVADRPIRDMRTVVLDNHQKMQVLADINEYLHPATPRWYANRGIPLRRGYLFHGPPGTGKTSLSFALAGVFGLDIYVISLLEPTLTEEDLGALPEAACRGAEQGRGGEEGGRRRQQQGNQQGQGGPSNDWKVSDLAKALKKESNNDDKKGISLSGLLNAIDGVASHEGRVLIMTTNVPESLDEALIRPGRVDLQVGFTNATREQARELFIRMYEADQGRRQQASGSGAATKTNGAAVVMAAANGKDPAATEKTKRGEDGGGGPAVAPETQSAMNSGDMDISVEELTEIAEQFAAKIPETKFSPAEIQGYLLKRKKHPLKAVEETDKWVDAMVQQKASKSKVLQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V617</accession>
    <name>A0ABR1V617_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662247.1">
        <property type="nucleotide sequence ID" value="XM_066816555.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049615"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="61" mass="6903" checksum="9C2EB8D8181FF9B1" modified="2025-10-08" version="1">MSRDPKNHASPDEFHGFRFVEPEILSRYSAEVSTRDFQMPEGAGPAQFTDMSGLPFWALGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6M1</accession>
    <name>A0ABR1V6M1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012723</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662729.1">
        <property type="nucleotide sequence ID" value="XM_066817037.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050097"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="53"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="5">
        <location>
            <begin position="331"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="675"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="686"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="715" mass="80068" checksum="E1F845F69954A9E8" modified="2025-10-08" version="1">MSSSTAVPRTAPIAIAPKPSRPSPRRQNSTTNACDTLTSSMNGHESADSDTPSSGTSLCDFCAQRRIKCVMTEDEETSSCVSCQANGVECSLSRSPQPRKRKLARDLADDGNFWRGSPGRSDNRRQRQHQSSLSSTTASNSLIEDMANFGGPTLLKRTLGLQHDRYSQYIGPTTDFEPSLINLSPFDPQDESLLARGTLRKVSENDTFLMLPDYTTSGHERQVEDVDEIERLVAPNGRKLIDLYFRVVHPSFPIIQRNVFYERFSPPLLAAIYILAINWWDLSEELSATPRPDIRRIEKIMRSSLADAMWRPKLSTVQAGLLLSQKPEGDQWAPTAQLVAIAQELGLHLDCTHWKIPPWEKGLRKRLAWALYMQDKWGALVHGRPSHIFSNNWIVQPLLPNDFPEAEYDENDVEEKLEIERGRTLFVQMVYLSQVLAEILETFYTLQAMHAVISAGPQGTHLVLSLAKPIQLKLKEWYSAIPANIRMDSSLALHNNTTGRLSSIGYLHLAYFATEITLHRRIIRSLEVNAQDVDSYLQHICRSAAKARLISAMDFVNRLTPQHLRAFWYFASKTNFALIGTFGSMLWATAPGREEADWYRRRLGEYRWTLSVSSKPGEGKGLTEFAMGMLDISAGLLKQLPEKPELSRSGSALEMSSGRRESILAMTMDAPRMEFQSDMASADVSGAQSPGSQTDSSDEMYDNSAPTGGLASMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6N6</accession>
    <name>A0ABR1V6N6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane ATPase</fullName>
            <ecNumber evidence="10">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_012738</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="10"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662744.1">
        <property type="nucleotide sequence ID" value="XM_066817052.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050112"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="445"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="808"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="871"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="937"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="983"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="119"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="298"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1013"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8065991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1039" mass="113137" checksum="9FF9EDB0014A51AC" modified="2025-10-08" version="1">MSFLRQRSDAGRAPADDDVEAGAVSYSGPVSPHYQARPEGQSTATEQGRQSDDVGPTEKVKGELPRNTDPPSSSQKGGVDDLPEYEALQRFITNYDAERRASFWRSSSTPVQPAHPVFKEGQPPSSWLETSIRQGITSHDIETRRKAFGWNELTVEKENMFAKFLGFFQGPILYGGWFRATLMSPTQVMKLAALLAVGLGDWIDFGVIVGILLLNAFVGFYQEKQAADVVASLKGDIAMRATVVRDGQGQQVLARELVPGDIVILVEGQTIPGDCQLICDYSRPGDYDEFVQLRNEDKFGDEGDGDGEPPGGATADGGDGNAEKDGEEDFDYEHSHYGLPLIACDQSAITGESLAADKYMGDMVFYTTGCKRGKAYAIITTSARYSFVGKTANLVQGTKDRGHFKQVMDSIGTSLLVLVMFWILVAWIGGFFHHIPIATPGLQTLLHYALVLLIIGVPVGLPVVTTTTLAVGAASLAKQRAIVQKLTAIESLAGVNVLCSDKTGTLTANKLSIRDPFVTEGQDVNWMMAVAALASSHNITSLDPIDKVTILTLKKYPKARDILRQGWKTDKFTPFDPVSKRITCECRLGSDRFVCAKGAPKNVLQLTEADDETRTAYTIKTKDFARRGFRSLGVAYKKNDEPWVLLGLLSMFDPPREDTVQTIIEAQALGVPVKMLTGDAIAIAKETCKMLGLGTKVYNSTKLMHSGLSGTVQHDLVERADGFAEVFPEHKYQVVEMLQQRGSLTAMTGDGVNDAPSLKKADCGIAVEGSSEAAQAAADIVFLAPGLSTIIQSIKTSRQIFQRMKAYVQYRIALCLHLEVYLTTSMVIINETIRPDLIVFVALFADLATVAVAYDNAHVEPRPVEWQLKKIWVISLILGMLLAAGTWICRGTMLLRSGGIIARFGSIQEVLFLQVSLTENWLIFVTRGGKTWPSWQLVLAILGVDALATIFCLFGWLSGSGGGVMRTTPPTVFNNSSNGWTDIFTVVIVWAYSIGVIVFIAIILSAQPDRLDQRPREEGPSCQGHAHGKCPGPAQQTGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6R1</accession>
    <name>A0ABR1V6R1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663608.1">
        <property type="nucleotide sequence ID" value="XM_066817916.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050976"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="298" mass="32915" checksum="8D399C540F0036BD" modified="2025-10-08" version="1">MGIAMAWASIYFFIHLAALLKEPKTKTSRRLVRSARDTTNTFFDAALVFAVSMLGAGVVRMASILLAEPDADGLPTGRAAVNAAYMSVFSVFPPLLLANVARTTAPHHTVRYALWAALAVLAAAIDVLIIVVLWGGGDKEAAGARESGLDDGADTLWAPCRLRRPVVVAFVVAHVVLWVNCLWQLAAMVSAMLPAKYKLIKEETTTTAEDEMKRGPREFLSDWRFIAKVGNGILCFAVGWVLLAVYHAHVRVERDFKPNANSWDFGQVLALATWATVFIDFLTRYLHHEELEQRHLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6R7</accession>
    <name>A0ABR1V6R7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662774.1">
        <property type="nucleotide sequence ID" value="XM_066817082.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050142"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="22691" checksum="D5A5856071BF6EE6" modified="2025-10-08" version="1">MTYTAYVCGDLNTRRGLSREEWLSSRRGHFGRANTGLWQEAASAILSDHIICASSREVYSKINAATTCWTTRSSLLWSPWVLLDLRKLHLHISPLYIETFVRKSFSKDSSRTIHGWRWAAAAASLYVGALIYGLDGTIAADIQTAIIEQFNDIDWAAFVGGTGAMVSLTMVLTFAGGAWTWNDGRTIAIFLVCGALFVLTFLQPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6V1</accession>
    <name>A0ABR1V6V1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663684.1">
        <property type="nucleotide sequence ID" value="XM_066817992.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051052"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11637" checksum="793EA5CD38C39E4F" modified="2025-10-08" version="1">MVAFPDTARFVSAFGADSETYIQRIGMNMFMPSPIIMFGDRSEDWDHDDDEALSRGGTPAITKVMNWHMDSYSSAVMLLMNFTVAISLSHAFVMKILNVSKSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6V2</accession>
    <name>A0ABR1V6V2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663679.1">
        <property type="nucleotide sequence ID" value="XM_066817987.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051047"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="540" mass="58037" checksum="DA0ACB5036AEFCB8" modified="2025-10-08" version="1">MLGHSVHAIYRLVGKQVLVTVITPAACHGSYLRASTPGFGSGDQAGSLSDPAYGSGTSYCGREPMPDARPDGAIKPTIVTFKGEDGNEDLGFVQYLANSYTNALNNTATGEASPPGPRAKRHQVPASPARSTGEAIISSHVWNSLTNHVTKVPAAVGPSHGSSYLCVQPVAARASTQWQCHRHFGSPHPRFRRTPRGRRALTLRRPESMTTSETTIPTYDLGVEVEMGMSSDILGVGIPSHVTSFTGSTHVSDGFGPAWSYLAVPRMVGIRIMVLDAHLVHAPYLAARTTDSLLDLTKFPRNSGMIFFETYIYAQANSLEALYADHGDPVQPYAILMLRIAELGATNNGAGSPRRLNTSPQVTPLIELLGSQVRYSTPAFSLNRFHPSLGEMPDIITVGLSTPSKPTRQRSTHHSDDDGDLHHASGTNHEDDALLRNLESPSHSGNAMAAPQRLPVTGGAPTRRMLKELIRTALSNIKGRYPHPTNSKARNAGTRHRRTQAKTAGPRPDRHIVDSSGVARSAPPTIDPLHEGSLEVSTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V795</accession>
    <name>A0ABR1V795_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662606.1">
        <property type="nucleotide sequence ID" value="XM_066816914.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049974"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42354">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42354:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="351" mass="39032" checksum="3B894A875970C784" modified="2025-10-08" version="1">MNYASMIEEKNLKKTFIIATLCSTLVGTFTSSIGLWDRVKERRQQTKRDTDQDKEIKELRKQVEGSGKQQNNRKSQDQQQNQYQNQQHHYQYEQPRCCSSGSRHGSRHRSPPPRRRREDEVAYALERSGALIGREFDEGYERLGRRFAIGDSVTENRLQAQVISLQQTVINVLQDALYNGRQLDNADMSKLIAASNAARDGSLDALRQQRQRQTLAIEAPPVPAVPMPPPAVSFATPRRAPSTLSGAEPLYCRYSLDLQDVRHKPLARSFAPGGDCRCPGCGIRLPAESDDFWEIEKRARGGRATGGGAAAAETPCWTSGSSTWASASWSSATRPRATSRACFAAGSATRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7Z0</accession>
    <name>A0ABR1V7Z0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662846.1">
        <property type="nucleotide sequence ID" value="XM_066817154.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050214"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="44"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="314" mass="35647" checksum="6C7569899AFC1A94" modified="2025-10-08" version="1">MSWAKSNGVPKTNPTRLLELDYSAEPPRARLLASTDRLGAHVRYVTLSHCWGDSVPLRLVHSNMGAMEDGIDIQQLPRTFQECFRVAHEVGIRYLWIDSLCIVQDSEEDWQREAGLMEQVYSNCYLNIAASESSNGTEGLFRERDPRSAGSTYVQITWVVQERFLSPRTVHYHQEQLAWECSESFTLEGLPAGVDLRKDASTLFKQHNASIATIPLSADKLYKVYELWDTLVIRYTTGCLSFSSDRPIAVAGIARVICHHLNLAPSDYHSGLWRPRFVEGLCWIVINTPRKTKHAFMNFQKTAFWAIRLGPGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V824</accession>
    <name>A0ABR1V824_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664066.1">
        <property type="nucleotide sequence ID" value="XM_066818374.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051434"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8067313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="69" mass="7887" checksum="6E469035E851A3AA" modified="2025-10-08" version="1">MESIHRLSTFARGLILLLRDENILRAEQRGCSKWLLDAEHPRNFAATNFVPIALPRAQNSMALPAQLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8A5</accession>
    <name>A0ABR1V8A5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663885.1">
        <property type="nucleotide sequence ID" value="XM_066818193.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051253"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="162" mass="16678" checksum="908C2FD875A16879" modified="2025-10-08" version="1">MSTLSADGSTVVLSVYLPGDETVTTTATATTTQFLPSNTATSYITTTKTVSKGRPLPPTATTSTASATVTPSDGVERNTGSAEEDLDVPAPLQPPTAHSANPAVIGGITGTFGKHHQHDNIFLLSVESSQANGVLPSSGSGSYGHPHIHHASAEEAEDRNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8U5</accession>
    <name>A0ABR1V8U5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663479.1">
        <property type="nucleotide sequence ID" value="XM_066817787.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050847"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="189" mass="21697" checksum="780C9BCD5B5E2816" modified="2025-10-08" version="1">MTSRQLRQAHLYSAFAFQAEAEFVDLIPVKERPCWDFECPFQHHNESPADGEDDGAEFYKSAAKHLFYAKELDRSYDILQDLDEDDKALCHKIISPPPEALEVLERKIPLIGTWKVDPEVWRRWVENGSPWMKKLLQQRHIVNSGTEPISQGALAAQYRAEGVTWQHPGDPGALFPCLTMTTDNPDYQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VBC3</accession>
    <name>A0ABR1VBC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663986.1">
        <property type="nucleotide sequence ID" value="XM_066818294.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051354"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="273" mass="30412" checksum="4F0348D3FD66F5F8" modified="2025-10-08" version="1">MFPSSGHALDIYEEALERRAHPKAPNPTIMLGCEPSPIYVFGTGVGMMPSSTLQRMRRHFTGSCDMTPKFDDTSLSQSFHMPLDVYSWRHLSEEEAKANVPRHLKRTTFDPETIRSPVKRSWSTYCGPGHAMVLAVLDLAKPPFEKTSENHLTRALCRALHQALAPDPQMQRQLRLKVDRDRGAWIRPDINNKDSSASASASSSSSLSPESLIGDTAVDINEENLATLYMSLNVEGPVTGPDPHLNPWARLASVPGILAHRRRYPRGPRPAWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGI8</accession>
    <name>A0ABR1VGI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010566</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664171.1">
        <property type="nucleotide sequence ID" value="XM_066814881.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047941"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="54999" checksum="048F363B26E9E3E3" modified="2025-10-08" version="1">MDPLTITTSIITLVDATAKVYQFLQSVRYADTHYATLRNELSTLTGLLRSISGIFQDCRRHHFALAAIDKTVWDQSRIAITDCQQTIDDLGALVARIGGVARSNSIFRKAKMTTQMHMHSGEAIAFRDKIHVSTVSLQTLLQIITVSLSLRSNASHDTTLRELTRLKQDLEISGRTARDFESYSINRSDRHLSRNLEGLVRAARDFHSNASNTASTILGDATSHGSVDFHRDQAYTDLTSVPRTTSAKRRHIKAFLNRQSPPSRSSSYMGSAIPSNAQKLASSDLELYADIVGVKVDVDVDNVLSEGLKKTAQKAIRNGNFQKAEDILKQALSRYKMDGPEDAHHSRLRTQLALCSILEGKRTGDLEDSIIDLADYRGTARIVADQLLYALALSYMHTLDFDKAERVCSLIDSNSTKSSGHKCPGKLEVFQLFFVSYRLSGKDLLADAIVEQLPELYFPGILPSVIDFMSECPELLTDSGITMRYYHPLVWSYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGN5</accession>
    <name>A0ABR1VGN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal 4-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664204.1">
        <property type="nucleotide sequence ID" value="XM_066814914.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047974"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006393">
        <property type="entry name" value="PRK08642.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="253" mass="26472" checksum="D1388997BB02EEA5" modified="2025-10-08" version="1">MKLSDQVVLVTGSSRGLGAAIARAFAAEGARVAINYRQNRELAEALAADIKPNGIALQADVTDPAQVEAMFKKAEEHFGQPVHTVVNNALPFFEFNGDARPQLGNMTWSAFDQQLQGIMRGALNTTQAALPGFSRLPDGRIINIGSNLVANPVVPYQDYTAAKGALLAFTRTCAAELGPRGVTCNMVSGGLLRTTDASRATPDAVFAQVAAAAPLRSVATPEQVAGAVLFFASPWASAATGQNLNVDCGLVMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGX5</accession>
    <name>A0ABR1VGX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trichodiene oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010636</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664241.1">
        <property type="nucleotide sequence ID" value="XM_066814951.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048011"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8070433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="523" mass="58397" checksum="85C2643F54370E31" modified="2025-10-08" version="1">MKTRRAANRRADRRVGAVAREDGREVHASGRDVIELALCKGQKERGSCVRKKFAVDTDDLLTTLGGDAVRSAIEKPHNPHQPPRTPRQRPQLLREAVQPRRALGQVRLGLGRLRRPLSTICTVKHHVHQRRRATLNPFFSKARVAGRIDIVQRSVLELCRKVDEFAAGSRSVARISLGAAISAFTRDVATEFVIGKRYHILDAQDFNAETATLPQTSGSLWQSSKHFPWYVSLMKRMPAFMVKRTGGDGVNAFIFFLQDMMKVTMEYYSTLTSAPPNDDGPGDKTRTIVYEILNAPIPPAEKSLSRVFEEVGTITRGGFETVANSLRMILYHIYADQEVLRRLRLELSGARRDKTTNNHASLDIGLGTIEQLPYLTAVLMEGLRLSPGLSTRAQRIAPDRDLVYDNRVIPAGTPIGMTTLLMHYDPALYPDPKRFDPERWMDRGLGERPRRPMLPLGGAPGSVLGCSNLAWAELYLVVAALVQRFDFRFDPAAMADVECSSDQFIIGTSGWDGLKTFVSRVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH69</accession>
    <name>A0ABR1VH69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664353.1">
        <property type="nucleotide sequence ID" value="XM_066815063.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048123"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="181" mass="19582" checksum="4CB9F7FDF442D968" modified="2025-10-08" version="1">MCLLYTQTQRCPSCKKILSQHTVMYESCADSCSCLSCSSVKAGKNKSNSRYKAYSSEEVNGVPMPTPAAEGTAHTTACPKAELIHGEPQWASRPCGFCRWQHSRRVRQQYMGVHFCMNPFTTDTATRTTVSAPPPPTSTARMERGKGSSSRAPSEVSDLSEGGWSQQSGGGGGGEQQQQHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHI0</accession>
    <name>A0ABR1VHI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664498.1">
        <property type="nucleotide sequence ID" value="XM_066815208.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048268"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="34"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="275" mass="30187" checksum="BF7C691D41D7BA64" modified="2025-10-08" version="1">MIVPSLDEPDQWRRASHATVKPELLDLYRTEKDSDVKIKCDGYTWSLHKSILCDRSKLFRDVLNGSPDELNHDVVSTARGICSHLLDDGVMTIDGSSDEEVEIALTPPLSSTTPPLGSASRIFEVAEYLALDGLQEVSIRTLIKSLERVKEALCHALTAKALQHGQGGDDLDGDIAAELREAFPEETLDDIHEICESAAPNSGFEALQQPTLDFMEATVWVFFGPGDALETFEALLDQDSALWFELVEYMMRGRSATQAAEAIALSRQGSSASMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHS0</accession>
    <name>A0ABR1VHS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664589.1">
        <property type="nucleotide sequence ID" value="XM_066815299.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048359"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046026959" evidence="1">
        <location>
            <begin position="23"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="229" mass="24392" checksum="DBBAC89E27E7D7F8" modified="2025-10-08" version="1">MQFLTVSRALTMSILALGAAVATPIPGNSSETFLDQRGCEQAWSWFCYIYTLIPDTAAAALSCHVGQFQALHPDRELHLALLLRPVRRCVLRDPAHDGAVRRFGGCTWTDRAGYLAAHRLGHVVPLHEHDVAVVAVRVQAVPAARVLAALEEGLETVGVGAEAERRGLLEVVEQEEEVGSGGGIVREGVLPAEVLGRRGGAGAAWSLGCFVGVSETDVNALLRRDGTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJP9</accession>
    <name>A0ABR1VJP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010724</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664329.1">
        <property type="nucleotide sequence ID" value="XM_066815039.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048099"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050463">
        <property type="entry name" value="Gfo/Idh/MocA_oxidrdct_glycsds"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43818">
        <property type="entry name" value="BCDNA.GH03377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43818:SF11">
        <property type="entry name" value="BCDNA.GH03377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045993917" evidence="3">
        <location>
            <begin position="23"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="30"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="5">
        <location>
            <begin position="164"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="320" mass="34422" checksum="1FE06C96BC9CA8B2" modified="2025-10-08" version="1">MRFTSSLLGFAVAALSASTTAAAKIKAPKRVAIAGLVHGHVAGLLPGLLKRTDVQLVAIAEPDKALSQQYASSYNLSSDLFHTDLDEMLQDQHPDAVLVYTTILDHRRVIEAAAKYGISSMVEKPLSTTMEDALAIRETARKRNVHVLVNYETTWYASNAAALAAARNGSLGAIRKVVVHDGHQGPAEIGVGPEWLPWLTDPVQNGAGALFDFGCYGADLVTVLHGGAAPESVVAVAQTNKPDEYPRVDDDATVVLRYNGSQAVLMPSWDWAYSRKDMEVYGTNASVTTVGAGSVVRGGRMQVWGRLRRCPRCRRSVAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VNE3</accession>
    <name>A0ABR1VNE3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665181.1">
        <property type="nucleotide sequence ID" value="XM_066815891.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048951"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046420271" evidence="2">
        <location>
            <begin position="22"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="277" mass="28959" checksum="25CD2C38203F400E" modified="2025-10-08" version="1">MKLSWSQALPAAILVLDVATASKCKHSPSGLSSSSTSISTTSSSEPENTSSSVSVEVIITTTIETSSSSSSSASDAESSSSSSDSSSASFSATSTTSSATLTQSSSSSATTLSSSVVVDQCSVGLLDRGGAPNLADRLADCSAYNTWTVTPLTSTTATEWYSTSWSFTSTSTETITTTSPSPVQVFSKRTMTPHGGVTATGLDGTVTVRPTDIPTYMSAYCGGYEAYFDACSEGRRHRGDQHGARRHVDDYRELGPDLLRQLHLHQVHRHPLPVLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VSZ6</accession>
    <name>A0ABR1VSZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD/NAD(P)-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009046</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665323.1">
        <property type="nucleotide sequence ID" value="XM_066813361.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046421"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF307">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="7"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8074383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="410" mass="44389" checksum="398C48E4A875A685" modified="2025-10-08" version="1">MIELLQGIGGLSAAVALGNRGHSVLVLESTSKLSPIGAGVALPPTTRQWYEAEGVLTPRDTICVPLEGIEITKWDTGELITRTAANSAGKQNAVHHGDIQLALLARAQQLANVEVRLGARVADLDVKAGVVVLANGDSVTGDLIIAADGVKSTLKSEVCPPEAVVPLSTGEAAYRFTLPRDLLESDERLLELVRRPWATRWDGPSRHVVAYPVRNHQLLNVVLIHPDGGDAEESWTSVADKSDVLTHYHGWDPALLRLIDLAPPKVPNFRMFLYPPSPVWVKGSAILLGDACHAMLPYLGQGVAQAVEDATAIAAVLSLITDRRQQLPLALRAYELSRKERVEPIQAATYRAREQLHLRDGAAQAVRDAQRRDTARSGKNSDVVQMQHSYWVWDAAGAAEKALAEMMSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT69</accession>
    <name>A0ABR1VT69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665398.1">
        <property type="nucleotide sequence ID" value="XM_066813436.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046496"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="143" mass="16482" checksum="982F2A90C2EE3D59" modified="2025-10-08" version="1">MVCSIRPGTVKLVDRYGPWFPNQSPEASPVAIGLWMEIFAHDFLVVYRRYGSVFSIDQLFEDTVQLHCRLPRFDCPGNDAFQGSYGIGNSTSKTCFHSPKSKFVRVPQCLPDIRRFTRNFVQVRFMNLEGQSKNRNFVHNLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUL8</accession>
    <name>A0ABR1VUL8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665852.1">
        <property type="nucleotide sequence ID" value="XM_066813890.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046950"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="200" mass="22099" checksum="50E9781C359603E3" modified="2025-10-08" version="1">MAAPGVQSLKCVVTGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSASVMVDGKPISLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSIVSPPSFDNVKAKWYPEIDHHAPNIPIILVGTKLDLREDPATMESLRSKRMEPVSYDQALVCAKEIRAVKYLECSALTQRNLKSVFDEAIRAVLNPRPQVSAKPKKSKCTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUS2</accession>
    <name>A0ABR1VUS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peroxisomal matrix protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009585</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665862.1">
        <property type="nucleotide sequence ID" value="XM_066813900.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046960"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8074922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="166" mass="17687" checksum="1E86D178528874D1" modified="2025-10-08" version="1">MPALKAGDAFPQGVTFSYIAPTPENAEITACGIPTKYDASKEFQNKKVVLVSVPGAFTPTCQADHISGYKAKFNDLKSKGVDQVVVIAYNDPFVMSAWGKANSIQDESILFTTDDGTAFSQSIGWTLGERTGRYAMIIDHGKVTYAENEPGKGVTVSGADAVLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVE6</accession>
    <name>A0ABR1VVE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">tRNA(His) guanylyltransferase</fullName>
            <ecNumber evidence="3 13">2.7.7.79</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">tRNA-histidine guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_009883</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 5'-end ribonucleotide-tRNA(His) + GTP + ATP + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54564"/>
            <dbReference type="Rhea" id="RHEA-COMP:14193"/>
            <dbReference type="Rhea" id="RHEA-COMP:14917"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:141847"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.7.79"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the tRNA(His) guanylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.79" evidence="3 13"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666160.1">
        <property type="nucleotide sequence ID" value="XM_066814198.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047258"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025845">
        <property type="entry name" value="Thg1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024956">
        <property type="entry name" value="tRNAHis_GuaTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007537">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038469">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729:SF6">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04446">
        <property type="entry name" value="Thg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14413">
        <property type="entry name" value="Thg1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028980">
        <property type="entry name" value="tRNAHis_guanylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 13 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNAHis guanylyltransferase catalytic" evidence="14">
        <location>
            <begin position="6"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Thg1 C-terminal" evidence="15">
        <location>
            <begin position="139"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR028980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8075220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="288" mass="33338" checksum="D1BBC89DA78C9F33" modified="2025-10-08" version="1">MANSKFEYVKDFERPDYLLPNTWVVVRIDGKGFTKLCAKYGFEKPNDKRALGLMNAAAKAVMTDLTDIVVSYGVSDEYSFVFHKTCTLYDRRESKLVSTVVSTFSAYYVYLWSTYFPDMPLAPPLPSFDGRAVCYPSVQNMRDYMSWRQADCHINNLYNTTFWTLIQQGKMDATDAERSLKGTLSKDKNELLYSQFHMNYNNEPEIFKKGSVVFRDYELVEPGSDNVAEKIDDLAEPVNQSKTQAENDKKRRAKARIVVEHLDVIKDDFWDRRPWLLSNKPGKIPKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWA9</accession>
    <name>A0ABR1VWA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkaline protease 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666480.1">
        <property type="nucleotide sequence ID" value="XM_066814518.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047578"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="1">
        <location>
            <begin position="146"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="277" mass="30674" checksum="FBEC9558426D3267" modified="2025-10-08" version="1">MEGPLYFKKDRNGFEYKSVPTRDPILQILSRAFKGHDGAKVESIDTKRLKAEDLAERSAVYDAERPDGPDKHGVAVLNRIGSAQYGSCRGKWCRCFVVRVRRAQDWDTLYNVNQWGDAMDVVREHFRKLQEQHPAYEFAVLNISHDVSNTESARTALQALVDAGFVVVAAAGNEKKDLDLLEVQGRYAPEDNPNTILIGALDEDWANAWEDGASGSNYGAPCPIAVGIIASMLSAGHITSKKPQDVRAYLDQCAVAGIRIQGRPVKHLRNHPGFVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWG5</accession>
    <name>A0ABR1VWG5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010246</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666523.1">
        <property type="nucleotide sequence ID" value="XM_066814561.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047621"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="150" mass="16638" checksum="0B0AE66531211EA8" modified="2025-10-08" version="1">MSTISTDGTRSDPFDDFKANIFYLFAEVEGRSVVGVRALGGTDGGCDAARGAHMWERQEDISGKKRRGSRYWEPGRDPGELPRALEVHTNYVQFTLYASRGPWNIIDTWDKVNGKCVEDRSGSYDCGPISGLSMYKCVGWAPPYNLAGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWL5</accession>
    <name>A0ABR1VWL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009218</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665495.1">
        <property type="nucleotide sequence ID" value="XM_066813533.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046593"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="399"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="908"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1002"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1047"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="921"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1008"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1057"/>
            <end position="1071"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1161" mass="129525" checksum="215CECCF83EB7C5C" modified="2025-10-08" version="1">MTSTPPEAGNTPCPTNASFGRFSQMESGPAATVTSDRPPIEDTGLSILYSPPDGVPIVDIIFVHGIQGHPVRTWSANGPEETTTGGLRKVRNWVKDGLSSKDHHATKKQPSAVFWPQDLLPEEVPQARIMTWGYDSMVVKPFSPTNKVTLFGHAKNLMFTLGRNAVPGRPIIFMAHSLGGILAKEMLANCDMSDNTRHKKIVDDTAGIMFFGTPHRGSKDLASVGEVARKAAGILLDTNSAALDSLGLKTTDLERSQEHFSRIWRRQDFRVKTWQEGTGISSMNLKYFKDKVVPDISSQLGDAREEAETLQGNHMDIVRMLSKTDPNYVAVLSEMRLMYTAIQDERQRAATLASTTDNNETANASSSGLDLKDQRACIQSLAFPDMKLREHSILQPRDGTCIWLSNHRSFKAWMSGTTPEEQVLFLRGKIGSGKSTTVKATMQDFGSRPGYLTAGYFFDSSATTTECRSAEGLYRSILYQLVSRDNELQQSFLKVAFQPWLESRDLEYGQTESWNLSQLQMVFHDTLRKPHSPVVVMVFVDALDEGDSAQLRRVVQDMRELVASTLGQGITLKLCFSSRNPIIGELGISVDECNSDDICLYVTKSLSVCTAEGEGSSRWQGIVKKITDSARGIFLWAVLVSNLVLEYHDQGENTEFITQRLHQLPPELGVLYGDLLRNMSTAKGAVTTYHVFLWAILSTGRLRLREWHHILPFLQEDPPCSLEQLRHSEAYIESDEQLERKVRFLTRGLVDVSHRGDLIVCDTGDVDDDNNMAEVDSARGGAGSLDTQVGETRIVQPIHDSVRSFFLGGDGFKILRAECIRLSDDGTYRRSIHDWAAPKPMREALAQGHYSIMTHCLAYLDVLELDGLALARGSRPNSPSGGKADYDTKVKVASGKWASIKNYQEYRSRVKSDQKRRKSTHSYQEYYRSTTPPIPTAESSYYKRHGSPVYEQHEYRARGYYYDGHHEYGASRRRGSVASFSSAGSSAGSPTTSLYEIRVQRPPDNPRYYQTNTGIQTASPRPAPGRPHSPSVMSMRATVVQNYLAQKDEEETEEVPQSPPGSDPHSPSPWSPDRPVCLSVFPALLHYATTQLLVHAARAEELGAQPGAMALFVRDKWRRYWLLRDEGPVPDMRGYCVETGLHAWVTALDTIKDYEENHSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX66</accession>
    <name>A0ABR1VX66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010513</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666790.1">
        <property type="nucleotide sequence ID" value="XM_066814828.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047888"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="148" mass="16557" checksum="10C74FA57B13C841" modified="2025-10-08" version="1">MAMMPAIKIFNLFEDYIGIHLETQDLRVELHHRLLPLVDILLPLLHLGLDLGDEPPVPRRRVHKWVLLVLYGAAVRDRHLAIVAGLGQVIIGAARGRLVEILGPQRPVVEDSKVLQVLLGFPDVLARVVELLFYLHDVVLGEGRALVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXA5</accession>
    <name>A0ABR1VXA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ACC deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010517</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ACC deaminase/D-cysteine desulfhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666794.1">
        <property type="nucleotide sequence ID" value="XM_066814832.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047892"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780">
        <property type="entry name" value="1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780:SF2">
        <property type="entry name" value="1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="4">
        <location>
            <begin position="20"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="185" mass="19934" checksum="A3B045A786798BD2" modified="2025-10-08" version="1">MSSQVKLPEPFASIPRESFLFGPSPIQHLPRISAELGGKVQVYAKREDCNSGLAYGGNKTRKLEYLAAEARAQGADTLVSIGGVQSNHTRQVAAVAAKLGLQCALVQEHWVEWSDPGYDKVGNIQLARLMGADSRLDPSSFGIEHKATLQKLEAELAGKGRKTYYIPAGASDHPLGGLGFARWAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXC2</accession>
    <name>A0ABR1VXC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666427.1">
        <property type="nucleotide sequence ID" value="XM_066814465.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047525"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="381" mass="40224" checksum="AB22DEF1E45AD691" modified="2025-10-08" version="1">MKRLRTRQRVGGGVGVVAVHIVLQRDLGREPVAVDELLHDALLRVPVLVDEDDLAPVPVAVVAAVPRGAPLLDRVGARVAVGRVRVVGHGQLDALGAQGQAGAVDAESVDHALLQDARSRVVDGRVQDLLEAGRDLGLVARDDGAHLAGDVGPGDELVVDPLRQGAGPRRDGPGEGHEADDGGHGLVEVLHGRDVVRGRDAEVRDDARQGQADDARAEGDGRVERVHVAVPVLDRDQAVPRRQLDGQARLARVAEVVEAAADYGGVALPEEVGRTERLRQSLDVVGLGRGDVGLGPSRKELVEVELRPGVGGQGLGRARGRAGGGQRRRPVISSTEDGGGGGRRRCRCRHLGDYGSRRDMVQGGHCREEGRGAHTGLMWYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZN7</accession>
    <name>A0ABR1VZN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666334.1">
        <property type="nucleotide sequence ID" value="XM_066814372.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047432"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="59" mass="6254" checksum="2587AE90971DAA43" modified="2025-10-08" version="1">MSLAIMPSGPTPMPNRDVGGLLFKSGWREELTGSCDCSVRFLIDLVSGKGASETSPKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZQ2</accession>
    <name>A0ABR1VZQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isocitrate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010072</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666349.1">
        <property type="nucleotide sequence ID" value="XM_066814387.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047447"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="ISOCITRATE LYASE/MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631:SF13">
        <property type="entry name" value="MITOCHONDRIAL 2-METHYLISOCITRATE LYASE ICL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="585" mass="63813" checksum="5611592915A714B5" modified="2025-10-08" version="1">MLRRAVLRAPRRLAPTLRTPTTLAATRAFSITTRNMSLPPVEPPLSAALPSDSFQLLPEASKAGAAEDALYEQQIKDVEAWWATPRYAGIRRPYTAADVVSKRGSQTQTYPSSVMARKLFDLIQERAAKGEPIHTMGAIDPVQMTQQAPHQEVLYLSGWACSSVLTSTNEVSPDFGDYPYNTVPNQVQRMAKAQSMHDRKQWDLRRKMTAQERASTPYVDYLRPIIADGDTGHGGLSAVLKLAKLFAENGAAAVHFEDQLHGGKKCGHLAGKVLVPTGEHINRLLAARFHGRLISSAIDVRDHEFILGVTEEGIAPLAETLQEMEAAGASGSEIDAFEAEWVKSTKLVSFDEAAVAQLSQQGVPQTKIDSGYTAVVEANRDMGINKRRELANGLLSGSDKPIYFDWDVPRTREGFYHFRAGMGAATKRAIAFGPYADLLWVETGDPNVKVAADLARAVRAVLPGKGLVYNLSPSFNWMAHGFTDATLKSFIWDIAREGFVLQLISLAGLHSTATITNELAKSYKDDGMLAYVNLVQRREKELGCDVLTHQKWSGASYIDGILGAIQSGSSGTKGMGDGNTEGQFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W025</accession>
    <name>A0ABR1W025_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666710.1">
        <property type="nucleotide sequence ID" value="XM_066814748.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047808"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="156" mass="16443" checksum="5D54B335B7DA4A54" modified="2025-10-08" version="1">MNAATLARYGPRGPGIPYISKITPIKRPDLHGPPLPTALATSIEEEEEATPTTAATTTGTRTSPRKVHPTARKLESEAATAVTKTTTTGRAPSGRRGQTPAKSPTKSTASGTTRTTRSVSQAMEEAPALPTPSEQEPPTPRTRRAPSPAKRGRARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7C7</accession>
    <name>A0ABR1W7C7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666864.1">
        <property type="nucleotide sequence ID" value="XM_066811522.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044582"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF4">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="58"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="292" mass="31830" checksum="24A117F038A49AA3" modified="2025-10-08" version="1">MDSPTPSIQPGVDGTKSHEVLKSPTTTGTPPTPRSRVSSMKTSLSRHVIRDGQIGTLNPVEVRDTPETGKGLFATQPIARHALLFAEEPLLFAPKGSDRVNNHKVRKFLEALDQLSVRHHADLMDLSFAPAALHAVGADSGNQDRMRNWYSQVKGLSGVKLDEAVAEGIHAFAIYRTNNVATMDDPAKPDEVTGGVVYSVFSRINHACDANAAFFYLGVRPQRLGVRALRDIAAGEQVFVSYIGDKAYKKMTLEQRRAGLASWGFQCRCDTCAKEEAAAEEAAKKKGKEEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W990</accession>
    <name>A0ABR1W990_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667087.1">
        <property type="nucleotide sequence ID" value="XM_066811745.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044805"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="404" mass="46237" checksum="924D01938A76397E" modified="2025-10-08" version="1">MENVMEALDILAKQKAKLHRVADLLLVIYQTLVEMRYLEPEEIQTGPHDVSALMPLYQSLGLAPAVIYLYSILPYVRLHKDRQHETPFFQGGDFADFRNKEDVEMGRDPIYNSPEGDDWKADNGPYMRPWYTALSHCGWRRWADKEEANREEEEEEGDDEGCVATTQETDGGEENADEPDVDEEEEDDGSDNDSGVSGMDEEESDYYEDEDDEDEEEDDGMIEEEGMVIGYDSRSAAAALRDINRWYREHETPFMGQGQDGPWTDEDKEHDVPLSALYKQHGWPGPDFDGDAFEVSLERRHAAARAKPDPDKPRRQAESDRYMLDQVDQSIKRHRAGIASAETADEEWAARWELFHAERSREGWVRKLRENEELCERGVPGRRVAQEGGSAAAGIREAPTRRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA82</accession>
    <name>A0ABR1WA82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bis(5'-adenosyl)-triphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008216</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>P(1),P(3)-bis(5'-adenosyl) triphosphate + H2O = AMP + ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13893"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.29" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667873.1">
        <property type="nucleotide sequence ID" value="XM_066812531.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045591"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051884">
        <property type="entry name" value="Bis(5'-adenosyl)-TPase_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46243">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46243:SF1">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="5">
        <location>
            <begin position="8"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="156"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="2">
        <location>
            <begin position="115"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="214" mass="23534" checksum="733640C4C7497D81" modified="2025-10-08" version="1">MTVNSETGPLRFGPFEVTSQVFYITPHSFALVNLKPLLPGHVLVCPQKPHKRLTDLSAPELTDLMQAVQRVQRMLARHYFTSSSSSSSSSAGEKAEEEEEQTGEDGAEAGQTVPHLHVHVIPRIHGATAKSGDGPGDKIYEMMADENGNVGGALWDREQQQQQREGGASSGRPQPGGGFPRIEDADRQARSMREMEEEAKLFRDVLGRLDREES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB65</accession>
    <name>A0ABR1WB65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008561</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668218.1">
        <property type="nucleotide sequence ID" value="XM_066812876.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045936"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="140"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="487"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="511" mass="57963" checksum="CC0F1DD316C291D9" modified="2025-10-08" version="1">MSAFFVNHGKVRARSVQLDKSITEEALAAQAVQAREQSGTPPAPSARSSSYPHKENQAPAPVRHIRSMLHVDAPTLGPLKPVLNSTDYAELYTHRIPSHASNGTASPAAMSSPPPSASGPPTSSINDSRNIVRRKLTGYVGFANLPNQWHRKSVRKGFNFNVMVVGKERKGPSLDIIPKTVQIQSISADIEEAGVRLRLTVVDTPGFGDFVNNDESWRPIVDNIEQRYDAYLDAENKVNRMNIVDNRIHACVYFIQPTGHALKPLDIEVMRRLHTKVNLIPVIAKSDTLTDDEITSFKARILGDIKHHGIQIFEGPRYELDDEETIAENNEIMTKVPFAVVGATNEITNAEGRKVRGRRYPWGVIEVDNEEHCDFVKLRQMLIRTHMEELKEHTNNNLYENYRTDKLTAMGVAQDPSVFKEVNPAVKQEEERALHEQKLAKMEAEMKMVFQQKVAEKESKLKQSEEELYARHREMKEQLERQRLELEEKKSRVESGRPIEKEGKRKGFSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBW1</accession>
    <name>A0ABR1WBW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Alcohol dehydrogenase-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008813</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668470.1">
        <property type="nucleotide sequence ID" value="XM_066813128.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046188"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF4">
        <property type="entry name" value="D-XYLULOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="8">
        <location>
            <begin position="40"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="370" mass="39768" checksum="9AF66E344CABAB1A" modified="2025-10-08" version="1">MASPNNNTQHVIKTSHPNPSLQVTADHQIKMVEAPVEEPGPGQVLLHIKATGICGSDIHFWKTGRIGSLVVEGDCILGHEAAGIVLKCGEGVTDLDVGDRVAVEPGVPCEKCFLCREGRYNLCDDVQFAGVYPYHGTVQRYKVHPAKWLYKIPDNVSYAEAALLEPLSVVLHGVKTGGLSLGRPALICGAGPIGLLALAAARASGAHPIVITDLEPKRLAFARDYVPSCITYQVNRDLSSEANAAAVRRLIGDDEYSAPPTVLECTGVESSVVLATFAVRRGRCLGKSVMNNLPFMHISLAEIDLRFINRYRDTWPAGLACLSGGILDVKKLVSHVFPLEKAMEAMDICSDLKNGSIKVQIVDEVTATIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC98</accession>
    <name>A0ABR1WC98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668092.1">
        <property type="nucleotide sequence ID" value="XM_066812750.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045810"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790:SF4">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="1">
        <location>
            <begin position="34"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="391" mass="46595" checksum="325BF54984FB7499" modified="2025-10-08" version="1">MEILPGPQLQKPPNQLEQAWVREFNWQVSQRVNRQEASPLFDRLPTELRIQIYKYTLTEEPLVNVHHHQFAVRFDHNDETLTPRPSFGTPSATRNIAGFDWVRPETPSAMVTYAGLLQTCKRVYQECVKFEIPWTQREHRFYFYRGLPRQTESEAQARFERFFSTTSLGWSLVPDRRHRDMIRAIRVFPQMYWLEDKRHNNLIWVVSNTDWFSNVETFRMTFRRGDWWYWERNEALKINPFRNGGRKQQMHQDMVTTQQGGQVPFADKAWGLAFEKMPRLRSLIIDFETNKDKRQEMEEIVKWAQKWKFPAAATSGESARHFSAENNPVEKMSWQGMTYHWSDRCIGCHKGRWQPINPDCPDCNEEKQLTGWGYGPRLLVWTLSWSSVPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCB4</accession>
    <name>A0ABR1WCB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-tRNA hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667248.1">
        <property type="nucleotide sequence ID" value="XM_066811906.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044966"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="entry name" value="Peptidyl-tRNA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="Peptidyl-tRNA hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="11219" checksum="49D97458332314C2" modified="2025-10-08" version="1">MNESGDAVAKAYRQFVSASASATVDEWPTLVVLHDEMELAPGQLRLGPGAASAKGHNGLKSVQQSLRSTGLGGPAGGEEGAVLAGRVRDREARGVDAEEGGCLGFRAGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCH8</accession>
    <name>A0ABR1WCH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_009028</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668685.1">
        <property type="nucleotide sequence ID" value="XM_066813343.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046403"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039577">
        <property type="entry name" value="Rad18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51908">
        <property type="entry name" value="ZF_UBZ4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBZ4-type" evidence="17">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="SAP" evidence="16">
        <location>
            <begin position="89"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="40"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="198"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8081210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="298" mass="32312" checksum="94A98C78AB0741EF" modified="2025-10-08" version="1">MARQEATFSVPPHSVPDQSYHDGLVACPICLERMKEVQVDRHLDSSCPGSPREQPTKPKPASGTQRNGFQALASPAPPPKPERLPTLSYSMLKDAALRKKLADLGVPTNGTRQILEKRHQEWITIWNANCDSLHPKRKSELLQELDVWERTLGTRAPTTSRSIHQGAQIKDKGFDHAAWSAKHDSSFQDLVASARKSRAKALQKANEGQPTAETLPQQGTGTSTTPVAAAASPSPSDMQVDQAPVSLDPSAISKPPVPTPNYEYTTPCMPDRSFAMAGISPLEATAVDRSRNGTSEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WED3</accession>
    <name>A0ABR1WED3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667938.1">
        <property type="nucleotide sequence ID" value="XM_066812596.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045656"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050849">
        <property type="entry name" value="HAD-like_hydrolase_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006384">
        <property type="entry name" value="HAD_hydro_PyrdxlP_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01489">
        <property type="entry name" value="DKMTPPase-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181:SF2">
        <property type="entry name" value="PHOSPHORIC MONOESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181">
        <property type="entry name" value="UPF0655 PROTEIN YCR015C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="28521" checksum="FA6E837778FEF0ED" modified="2025-10-08" version="1">MGSTNQTNLPALATNPKAIFFTDFDGTITLQDTNDYMTDNLGFGYPQRRSNMDDVLDGKRTFADAFKEMLDSVKTPFDECLRVLKDNIKLDPAFKEFFDWCRANNVPVVVLSGGMQPVIRTLLAHLVGDEAVKHMQIVSSDVAPSPGHTDINEEGGWTIAYHDESEHGHDKSLEIRPYAALKERPVMFYAGDGVSDLSAAKETDLLFARAGRDLVIYCEREKVPFTVFHSFSDIHKIVQSVVEGKQTVQEAATGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFS0</accession>
    <name>A0ABR1WFS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Asl1-like glycosyl hydrolase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668418.1">
        <property type="nucleotide sequence ID" value="XM_066813076.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046136"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF3">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045438121" description="Asl1-like glycosyl hydrolase catalytic domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="2">
        <location>
            <begin position="27"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="310" mass="33458" checksum="4818516AB52F40C4" modified="2025-10-08" version="1">MRQTAQLLLLALGSSIATASASNKRGLVFVPNEQWPQDSQIWVKPGTDLTWYYNYKMTPAPSFADVPQDKFEFVPMMWGKVDGTTFLDSVNQQLDGGRNISHVLGFNEPDGAVSGGSNLDPESAAQIWVTNMEPLAKRGVKLGMPAVTGSDRGVKWTQNFATECAKVANKNCTFDFLPIHFYGSFEGLASHMGSLSASFPNVTQWITEYNWDNQDLSTTQSFFNTTCEYFDRLDSVARYSYFGSFRSKVSNVGPNAVMLNNDGELTDIGSWYLGGSATGVNPQSAAGKSGASVLAAVAAAGIVGAVLASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL89</accession>
    <name>A0ABR1WL89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668781.1">
        <property type="nucleotide sequence ID" value="XM_066809858.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042918"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053008">
        <property type="entry name" value="Phomopsin_biosynth_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="232" mass="25431" checksum="B6EF43E1BA3C658C" modified="2025-10-08" version="1">MGNRHLRQDHDITLDSPKGRKPVPTSAASPDGIQCGRSLVVAVLGHIPLAAPADNPPQFHGPPAPRPNTDEIAFDCGQTYAHAVARNCTLDIMSGAWIPAPCYNATAAREALSPSTAVANLTGTGFLHWFREWEHTHPVPLDELWTLDSLRAYTWQSYHVVHCLYSWEVLTRAVARVRAGEKDVYIHSKLLSESHTHHCAMVIAANAAETDLYRGTKVELQIGLGECARMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLU3</accession>
    <name>A0ABR1WLU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668991.1">
        <property type="nucleotide sequence ID" value="XM_066810068.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043128"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="155" mass="16696" checksum="0691F4EC88ABA513" modified="2025-10-08" version="1">MPSSGITPNRSGSPVPGKRQPWKENWDALSIAEPTEVGTDHGFERGEQMVMDGNIAGNHLKAEGDKKEPVEAKESDDAQKAMGAIQESGDTKTSEDTKTSEGIKGSEDTKEREDTMEKEDTNESEKTEVSKSDEDGKGSENAEEKGEDGGKHVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLX9</accession>
    <name>A0ABR1WLX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005714</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668952.1">
        <property type="nucleotide sequence ID" value="XM_066810029.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043089"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF93">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="27"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="300"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="355" mass="39176" checksum="F6DB048A86937C34" modified="2025-10-08" version="1" fragment="single">MAMGGDGPWAITVMWALTAATFIFVLLRTYTRVVVVKSFGIDDGVYILAFVFLVCYTAFTTISARYGFGQNMYDLDPDDSVRAVLFEAIGQTFAVIGMAIAKWSLGIFLLRIVLDESHKWAIWIAMAALMAASISVCFVFWLQCTPPAYLWDRRIAGYCHVDSTPVSMTLCSEFESYMRPRRLLLRLVPLAVHMETEHGRKGEDCHPRQHEPGSHVRTDISANKPPICTMLTIPGTVQELAGSNGHSRCQSYPARTIPVEDTVGLIVWSAAEIAVTMICIGIPVCRPLYKRFLTQLTSSDRSKYKKGRNEEQDAFAMHTFGGSTLKPRDSSALEPSAAAATGKGLGGGEEEDLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM31</accession>
    <name>A0ABR1WM31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ca(2+)-dependent cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669103.1">
        <property type="nucleotide sequence ID" value="XM_066810180.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043240"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="5">
        <location>
            <begin position="98"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="392" mass="43086" checksum="0594D3809E83D785" modified="2025-10-08" version="1">MSNYNYPGQSYGAPPPQQYYAALLNHNTAAMANHRRRATTADLVRPSPWATSFCVGELLTTDASNAYQAPPPPPAAPQSFGHGAPQGYAFQYSNCTGRRKALLIGINYFGQRGQLRGCINDVKNMSGYLVEHFGYKREDMVILTDDQQNPMSQPTKQNILRAMHWLVKDARPNDSLFFHYSGHGGQTKDLDGDEADGYDEVIYPVDFRSVGHITDDEMHRIMVRPLQPGVRLTAIFDSCHSGTALDLPYIYSTQGVLKEPNLAKEAGQGLLGVISSYSQGDMGGVAKNVMSFFKKATNGDDAYNRTMATKTSPADVVMLSGSKDDQTSADATIASQATGAMSWAFITALKKNPQQSYVQLLNSIRDELATRYTQKPQLSCSHPLDTNLLFVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMB0</accession>
    <name>A0ABR1WMB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mandelate racemase/muconate lactonizing enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005946</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669184.1">
        <property type="nucleotide sequence ID" value="XM_066810261.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043321"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046945">
        <property type="entry name" value="RHMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794">
        <property type="entry name" value="ENOLASE SUPERFAMILY, MANDELATE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794:SF58">
        <property type="entry name" value="MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00179">
        <property type="entry name" value="mandelate_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="4">
        <location>
            <begin position="202"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="434" mass="48263" checksum="39DF6C6E1F8BAE1B" modified="2025-10-08" version="1">MPEITITGWSTRDVRFPTSLDKTGSDAMNAAGDYSSAYCILETDSEFSGHGMTFTIGRGNDIVCAAINHLGDRIKGRTLSSLVEHWGETWRYLVNDSQLRWIGPEKGVIHLALGAVVNAVWDLWAKVLGKPVWRIVAEMTPEQFVDCIDFRYITDAITPDEAVALLKATAADGKKEERMQDALASRAVPAYTTSAGWLGYGEDKMRGLLQETLSKGYRHFKLKVGGSLAQDRKRLAIARDVIGYDQGNVLMVDANQVWSVPEAIAYMKELADFKPWFIEEPTSPDDILGHKAVRDALKPFGIGVATGEMCQNRVVFKQLLMSGAIDVCQIDATASPSCRTRAASACPEYTQHLSTIDYVVVSGARSVLEYVDHLHEHFLHPSVIRDGYYQTPMEAGYSVEMKAESMDRFEYPGKEGVSWWRSDEAKPILEGEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMD4</accession>
    <name>A0ABR1WMD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavoprotein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005948</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669186.1">
        <property type="nucleotide sequence ID" value="XM_066810263.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043323"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359:SF21">
        <property type="entry name" value="FLAVOPROTEIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359">
        <property type="entry name" value="HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="3">
        <location>
            <begin position="100"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="607" mass="68510" checksum="D133F538353E5B60" modified="2025-10-08" version="1">MPGNHSRSSPSPDGLSSSLRRRHIPTLTTSSSCSSFQDMARTRKLRMLVAANGQRDVAYAQAIAVRLLKDTQVETRALVDEVPTRLTHDIIVMENRSLATLAIDADQRTREAIESARQTSYELVDWADILVLAPIDADHLAKMMSGIADTLLLEILRAWDVSKKILLVPGMSIQMWENPMTKKQLSKIKRKWTWVKVMSPILWQYDGAAPLKRMVSWDGFNDLVGIIKNQAELLSLGHDVEVAAQQALHTSQPNRVATALPPEIWTLIFDYVGDWELAQALGVYTSLKAPKEWQTDRTRLTDPIAIYMNELEWLILSCPGSDAICRKLSQAPHDLRYISSLAVKLIIKFSQTEVLTYLETNLSKEAFWASFSSKLLPNKASGVYGRIDILDWWNTSPSFLKKEYDTEALDNASRMGYIHILDWWRDSGLPLKYTDQALESASARGHLLVLEWWRDLAEQDDNIVLKPGRSLLQAAQSGQTAVLRWWESSGIPVAHGEGVCKIASAHGHTAVLDTWRELKGDKLSFDAYVLVAPTRQGHVNVLEWWKQYARGEQAGDGRTHRVEYKTCDIEEALEDAIGDDRPVRVWWARNGLNLGLGTSEWMKTKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMQ3</accession>
    <name>A0ABR1WMQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669328.1">
        <property type="nucleotide sequence ID" value="XM_066810405.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043465"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025213">
        <property type="entry name" value="Sim4_Fta2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13095">
        <property type="entry name" value="FTA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="43558" checksum="AD3E1C332A9F5842" modified="2025-10-08" version="1">MAALPRVNGPKLIPFGKSAGERCDIGFIKQLGEGSSGYVWKVRIDGDVYALKMRADVAQFKCPGYDPDHYEELLDFLKQCRDLKEACGYTEADINEEKSQFSRESRAYGRLKECNREDLSVKCYGYIQLDGTNEKELAEKGVYDWSRWDGPKEPVMAIVKEYIEVPDKTQDEVQDGVQEEPLIHCRSWLSENDDEEEDEEEDERRLKEYRFQMHKRSWQNKEHLFQEKDIPQMMEDLHSLHKLGIWVGDIKPENYLHGKIIDFSSSLTMPAFSMDPRIDGPSSSTGGTFDRAELNHVIREYYKYCLPEKENKYEMVIKPRYQTRFPKRTPVFHSRDRPCLLRPLFRWYTTASKERQGWQEQRFEGRGTVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMX7</accession>
    <name>A0ABR1WMX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Short chain dehydrogenase/reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006167</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669405.1">
        <property type="nucleotide sequence ID" value="XM_066810482.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043542"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="33289" checksum="E3A1E8B531167A0B" modified="2025-10-08" version="1">MNWSAEASSGQTVVVTGGSSGIGLAMARYFASKGQHLYILDLSTETGEAVAKQLSSEFPGATVSFRKSDVSSWDELSRAFKDIYASRGRIDVVMANAGISEHGSSSLLAQEEDEPSQPSLKTLDVNLTGVVYTVKLAVHYMSKNQPSPANDSRGAIICTASNAGIYPFPVAPLYAASKGGVISLVRSLGPALERTQIQINALAPAVLGMSCQIRSDRGRSAPACIHVREDGKQRANEGKPETNIAPSRDLFTNMVVTPMSTLVRGVDQLLGDRSTTGAVAEIHGGSVTLRPHLEYVDADSKANLDNFWRLGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNF6</accession>
    <name>A0ABR1WNF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein SQS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_005833</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SQS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669071.1">
        <property type="nucleotide sequence ID" value="XM_066810148.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043208"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02646">
        <property type="entry name" value="R3H_G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034082">
        <property type="entry name" value="R3H_G-patch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051189">
        <property type="entry name" value="Splicing_assoc_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14195">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="11">
        <location>
            <begin position="563"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="G-patch" evidence="10">
        <location>
            <begin position="694"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="100"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="370"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="382"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8084562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="739" mass="81074" checksum="29B52EC55CFFBE09" modified="2025-10-08" version="1">MARRKPPKKFSQGGPPSQGQGQGSSSGPGGRGPRRDPLLDVIRSSTPAFRGPNRGPHTLADEARSTAQRRRGGPAQDGKLRYNPVKFVSAGYMNPSDELKVLQDQDKQTAPAEAPPAVSNAAETDVLDDTMAVDARPGSNDITTPAESEERNRVSVDVDVGATDVVPSMDTVAADAHPATAPSPPLFVIDTAGDKSLRQKYPEVPIQTQDESGHDPVLQDSDSSEEVILFRGRNPSRQTTAPVTRSTNTPNPDSDFMQLSQINTEIQVVEETIQAPNHQNSSSTAEIDVYKTADVDVYKATVADQPPSKEPEDDQRFEKLLSGTHSDEEAAMIADYIANMEEDENDDDDDDELDQHPGLGSHAFHLLRDIGGTDSDGLPDGLLDEDSLDESGEQPDRNDGKGAQQTTSQGHDERLARMLAKQEQMGLGGDVIFLYDGTGSGDDGGDDWNIAPKTTPRRKKKGSSKTAKIIQKKGQYPSASKMAEAFDELDLMDWHRPSLHNYNKRSQVPYVSDSELEEAMNATFQKDRMKKAEKKKQREALRAQGLLGKNVNPEDPRIKYPGGMTKDDLVYELEQFILGDDEQLSLPPLDKHSRRCIHQVAAQLKVKSQSAGKGVSRYPVLYRTKSTVSYDERGFTSATRFLRQSYYPRVDVDEEVVKEYKALRRKDPNVKRGHAATSYREGEVVGQHASELASDNKGRMLLEKMGWSKGMALGTTDNKGIMVPIVHVVKKTKAGLGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ70</accession>
    <name>A0ABR1WQ70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">18S rRNA aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="6">2.5.1.157</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TSR3</name>
        <name evidence="10" type="ORF">PG997_006937</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(1)-methylpseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1191) in yeast 18S rRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:63300"/>
            <dbReference type="Rhea" id="RHEA-COMP:13852"/>
            <dbReference type="Rhea" id="RHEA-COMP:16309"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an N(1)-methylpseudouridine in rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine in rRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:63296"/>
            <dbReference type="Rhea" id="RHEA-COMP:11634"/>
            <dbReference type="Rhea" id="RHEA-COMP:16310"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
            <dbReference type="EC" id="2.5.1.157"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TDD superfamily. TSR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.157" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670175.1">
        <property type="nucleotide sequence ID" value="XM_066811252.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044312"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01116">
        <property type="entry name" value="TSR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022968">
        <property type="entry name" value="Tsr3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007177">
        <property type="entry name" value="Tsr3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426:SF0">
        <property type="entry name" value="18S RRNA AMINOCARBOXYPROPYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="Fer4_RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04034">
        <property type="entry name" value="Ribo_biogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNase L inhibitor RLI-like possible metal-binding" evidence="9">
        <location>
            <begin position="42"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal" evidence="8">
        <location>
            <begin position="79"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="207"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8085666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="404" mass="45314" checksum="001EE8A480FA82C1" modified="2025-10-08" version="1">MVRHKKDKFAGRGGKSHGPPRNSRPRGDDSEDPTNGGRPPFKAACWDLNHCDPKRCSGKKLIKLGLMRDLHAGQRHNGVIITPNGKHTISPADKELMDQYGAAVVECSWARTQEIQWSKFGGKCERLLPYLVAANSVNYGKPWRLNCVEALAAAFYICRHPDWAEQILSFLKINSKLLKKYAACEDEAGIKKAEADWMERLEREYAENRGDEDGDDLWKGGNLNHRIEVPSDDDDEEDDDDSSEDDEDADSDESVDGIYLGKKKKQPQSQWPRPGESSGAQDDEDRDPFAISDDSDDDMEEIRRRVLASKTFTNPDNNATQKKKPQTVPRPQQQKFQVDPNAEPDSDNGEDDDEDGDDDFDNIIDATPVTDRVGLAKLEKERARANVVTSRSFVTGGAEAPKKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQY7</accession>
    <name>A0ABR1WQY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Terpene synthase</fullName>
            <ecNumber evidence="4">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006718</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the terpene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669956.1">
        <property type="nucleotide sequence ID" value="XM_066811033.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044093"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201:SF4">
        <property type="entry name" value="BETA-PINACENE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201">
        <property type="entry name" value="TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01020">
        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="38146" checksum="277EA7E181606B28" modified="2025-10-08" version="1">MPSTDIRITIPNFMAPWPSGKGWPWDATPHVESDSIKAESEQWMRSYDGIEGAFVDKIMRGRFPDIACLIYGHQAREHCLLQALIMLHFFVIDEVTDHEGEIAVREKAEAMTHALRNPGSLAALPADTWVGVRMAADISARYSAIGTRASWQFFVDTFIDYLDGVVDEAAARDKPILSRADYLALRTKTIGVLPGMAMALIECELQPGFLDLDVVKSLMGLTVLILIHQNDMYSFDKEQVRGEDGHNGVRVLMEERGLGVQEAMDCLGRETGDLVRQFVRLCENLPRLEDETNDKHFRVVRDGCVSWIIGMEVWYTQVTSRYGMQNLGKDRSYRPAQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRK3</accession>
    <name>A0ABR1WRK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CASC3/Barentsz eIF4AIII binding-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669759.1">
        <property type="nucleotide sequence ID" value="XM_066810836.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043896"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="438" mass="46156" checksum="9FDCB33101FF54B6" modified="2025-10-08" version="1">MAGPRRRKIGHRRRVEDEGEDDLDLDDDSLTDGSLASDDDDHANDSDTSNVDEVSPTSPATKKAGGTANSNGTAKAGVASSAPVAGSDTEKLSKSTSLSNSMSGLSISEQPGAQESGQGEDVNDSTSASKSGAPIVVSSAIMDQPQDGQPFERRRREHDEYRRRRDEDPSFVPNRERSSCTITDTPALPPMGSDLSGEEVGVEAAQVHNTADPTVSAPWAHDMHEIVTEPAPSRQPRHTVAHSGHSMMDDGPPNGDGFIPTCPSNATPINRTLSCEKHIGNVQVRVFLPQYKEPVVFSGHAVKQYTSNACGASLDLGLGRSAASPRRTSVFGGSYYNGSVYSPSVALSRRSSIAPDLGRDYLLSPTGSAISRPPMPLDAARPVVRLPPRVEPPPVMNAVGMGEYPADGAAAGGQTTINDLPQPQIHPLPAEASGDARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRM0</accession>
    <name>A0ABR1WRM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669804.1">
        <property type="nucleotide sequence ID" value="XM_066810881.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043941"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="93"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="25172" checksum="B9E3300F76F23A14" modified="2025-10-08" version="1">MVAQVGQPLPNGMLVLLIRTEEELQCYSSSLTRLLVQGMEDNRTDRSRPWNYAFCLGAGFYYHHTLPKNLGRWRSMNDVLQQPPPTLREFLLFIIAHPRDNIPVASLEVLADVNSRTKTAELIDLVVAREYRCRGLITPFVSIVMRCLHVELHSMRIQAWTQPETAIHNLYERLGFLERTVQPGDGRTTAPLSLLEYRFHDGHQWPTVVRHDKLQKGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRQ1</accession>
    <name>A0ABR1WRQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">3-keto-steroid reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006219</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669457.1">
        <property type="nucleotide sequence ID" value="XM_066810534.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043594"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051593">
        <property type="entry name" value="Ergosterol_Biosynth_ERG27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43647:SF1">
        <property type="entry name" value="3-KETO-STEROID REDUCTASE ERG27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43647">
        <property type="entry name" value="DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="482" mass="53023" checksum="BFD958325F59A482" modified="2025-10-08" version="1">MAAAPWAGMPSNEQFFVLLTGANSGVGQGICQRLIDDFLATRSLSAHLVLIPTTRSPQKSRETIDSLRAYLAKAARTSTKLRSRAGSDYDPESAVARVHLLAVEVDLCKLPSIYDAAAKLLGGQVRDPTGVVAGGQDLKIPKLDAVLFNAGYGGWDGIRWFEFARQFFTVGLVQSTTFPSFKSSQAGHTLPLQEVPGNKSDDEDGAGQPRLAEVFCANTFGHYVLAHELMPLLTRSDPSEPAARVVFTSSIDAEERHLDLDDFQGFKSTAAYESSKRITDLMCLTSELPSVQAVSSSFFSSGASSSRKYTKKPRLYLSHPGIVCTPLFPLNAFMFFFYYYAMLLSRLLGSPWHGVDPYIGACATVWLALEDEAALDASHAQRVKWGSAADRHGRADPKKTEVEGWGWEGKVEDAEALKRDEASGVLRKLTGRKWDAVQLTEEKRAKFEEDGVRCWKELEALRGRWEEIMGRRPNSAEKVGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWX8</accession>
    <name>A0ABR1WWX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670564.1">
        <property type="nucleotide sequence ID" value="XM_066806946.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040006"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="23710" checksum="36A1E181A2454B52" modified="2025-10-08" version="1">MSEASQNHSQDQSRLLALPGEMLNQVFLEHCNTWDQMRLRQTCHAVREIVPAPTFDDLYRLEVEHNEGNPRLREKNRLYTCPVCLLLRRRSKFEDKMLKKGRRRRREPSARLCVDCAYEGGTPPAATGDTGGYSTITILNVHWVKCIYCRHLAPAALDERWKNHDRPGGPRRAFRVGGENTAKAARSLCRYTRRLRVIITRRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWZ4</accession>
    <name>A0ABR1WWZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670528.1">
        <property type="nucleotide sequence ID" value="XM_066806910.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039970"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF14">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="87"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="230" mass="25662" checksum="1B67B7590B907257" modified="2025-10-08" version="1">MADATPAAVESSGKKDRIPWKIETPTPADVSDIVDVQWNAWTSERMQSLFPHTASGRVYSERDHLLNVTGQPKRPGSDKPEPKTTMRVVRDVGTGKVVAFAVWRHMRPGDDWGWQACWSEFDDIPDIKLETVEEIFGPSRRVQGLLMDGREHLMLEALATLDTHRARGIGTALVEWGNAYADERGLPSFLLASPLGKAVYEKVGFAVEDVSHLTDEKPFSVPMVRPGKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXL7</accession>
    <name>A0ABR1WXL7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_002872</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Plastid</location>
            <location evidence="14">Chloroplast outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670805.1">
        <property type="nucleotide sequence ID" value="XM_066807187.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040247"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045058">
        <property type="entry name" value="GIMA/IAN/Toc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903">
        <property type="entry name" value="GTPASE, IMAP FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903:SF135">
        <property type="entry name" value="TRANSLOCASE OF CHLOROPLAST 120, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1002">Plastid outer membrane</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="G" evidence="16">
        <location>
            <begin position="24"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8087911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="387" mass="42891" checksum="F3641B0B17BE15C7" modified="2025-10-08" version="1">MRPDLFQDGGQKHTSDHDASQPLIAVMGTTGSGKSSFINHITSDNAAKVGDSLEACTRHAHMINFQLDGMQGSIIDTPGFDDTNLSEYQILEEVSLILQTLYHGGKKLSGLIYLIDITSARWKGSDASNLTLFSKICGEDSYKNIIFVTTKWDLIDDEKAVKNEAQFKEKYLSFHIQLGARLMRHRNTSETALRVVSSILGQSETVLKIQKELVDGRMGLKDTVAGLHLATSLQQSVESSSKRLAKFRNEWRAASSPIVREALEAAMATEETKLRNSKIDQEKLESANQATKFFELANTMDQAAKFTGMSRSDLISILVTKGLAFFLQSAYGMVSKRTDSNTEIELLKQELRNVKEGMEAKNGSVYTSWSDVAKILGDVASAYNRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXZ5</accession>
    <name>A0ABR1WXZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal recognition particle receptor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_002966</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP receptor beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670899.1">
        <property type="nucleotide sequence ID" value="XM_066807281.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040341"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04105">
        <property type="entry name" value="SR_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019009">
        <property type="entry name" value="SRP_receptor_beta_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09439">
        <property type="entry name" value="SRPRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8088005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="287" mass="31187" checksum="186C0B70DA629B7B" modified="2025-10-08" version="1">MPTPMEQLIEYIEYILTPSTPVFVVGALIVVLVPIIVHIFVTQSTPYTSLPSVVLVGPPGAGKTALLTLLERGDAAISTHTSQVPQSIELTVSVDQHLSFREAVKDDAPGEHKKFLLVDTPGHGKLRNFAMDSLVAREGLKGIVFMLDAATLDENLAATANYLYEVLLALQKRVSSVKTSKTPSAINVLIAANKSDLFTALPATLVKSNLEAELGRIRKSRSKGLLASGVGIDDVDNGENDDWLGEYGSEKFTFGQMQEFNLEVDIVGGSVTEGKVDKWWHWVSERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYS1</accession>
    <name>A0ABR1WYS1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endoglucanase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003272</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 12 (cellulase H) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671205.1">
        <property type="nucleotide sequence ID" value="XM_066807587.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040647"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002594">
        <property type="entry name" value="GH12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002">
        <property type="entry name" value="BLR1656 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002:SF10">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01670">
        <property type="entry name" value="Glyco_hydro_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046228362" evidence="3">
        <location>
            <begin position="18"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="239" mass="25678" checksum="127533EF695F545D" modified="2025-10-08" version="1">MKSTLVVLGALASLGVAQQASLCDQYGYHASSGYYFNNNMWGKNSGSGSGCTYVDYANSNSVGFHVNWQWSGGDNNVKAYPYAGRTLDSKRTVASIGSIQSAASWQYSGNNLRANVAYDLFTAADPNHDTSSGDYELMIWLGRLGGIQPIGSNVGSVNVAGRTWELWDGYNGAMHVYSFVAPSQANSFNANIKDFFNYLSSNKGFPANNQYLITAQFGTEPFTGGPATFTVSSFSLNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ77</accession>
    <name>A0ABR1WZ77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003373</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671306.1">
        <property type="nucleotide sequence ID" value="XM_066807688.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040748"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF147">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="57259" checksum="3FBB89FD91E2F332" modified="2025-10-08" version="1">MAAPGIVGLVGILVATYLVYQFCKAVYNISPLHPLSKIPGPWLAGATYLPEFWWDVIQNGRYTSKIVEMHRKYGKDHLKGRYEIYAVGGRKRDKPLHQVNGSILNLAEFGTVDHDLHRLRRAPVGRFFSRSMISRLQPDIKTLVRKLCDKLLAQKGQPAFDIAVAYSCFTADAISGYAFGQNFGLLDQEGWEPNFHEPTLSSLRPGLLFRFFPFLKGAAELAVHFVDYLPASTGLFIRELQINIPRQIRQTKADLDAGVAVEKEHPTIFAELCKTNDLQEDEKTVARLAAEALGIVGAGTETTSWTLAVVTYHLLDERELLERLTKELQDAQIDPMDLPHWTELEKLPFLRTVIQEGLRLSYGVSARTARVATHEDLHFRGEWAKKPLYLTIPRGYAVGMSSSIVHHDERIFPDSHRFAPDRWCEGTALWTPDVDRGMFSFSKGSRSCLGMNLSLCEMNLALAALVLRVMPHMRIFETDESDLRYDHDMFIPMPKSDTKGVRITME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZS1</accession>
    <name>A0ABR1WZS1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA polymerase epsilon subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003596</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671529.1">
        <property type="nucleotide sequence ID" value="XM_066807911.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040971"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22906">
        <property type="entry name" value="HFD_DRAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF5">
        <property type="entry name" value="DR1-ASSOCIATED COREPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="4">
        <location>
            <begin position="260"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="340"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="128"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="189"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="378" mass="42147" checksum="ABDFBC36A55E0CCC" modified="2025-10-08" version="1">MSTGAENDGASYAPRSPDLSSFFTSGPEPVALPTYAHSGIPVEYASSSLQPHLRTLQPHRSFPQNYPPQPPQPQHSSPLQQQQTHHYGLHQHHQQPRQTHPRPPTPHCSSPSISHNNTRRHSRTSRCLLQLQPQQPQPQAQYHQQQAPSSHPQQQQPQQHQRQQQQQQQQPQPYFPSAYQANHNVNQYQPPPPPAPVPAHTPAAPAPAPAPALEPPSPASRPPIKHEFPAESEPISAMPPRKASQVKEEAEIAPSPVKTKFPTARIKRIMQADEEVGKVAQQTPIAVGKALELFMVQIVTKSADVAKERNSKRISAQMLKQAIDSNNEWDFLRDIVSKVSEKEDTSRAGKAKVETESEEEVEPQPKKRRGGRKKKSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X055</accession>
    <name>A0ABR1X055_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671649.1">
        <property type="nucleotide sequence ID" value="XM_066808031.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041091"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF313">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046892457" description="Amine oxidase domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="43"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="421" mass="47515" checksum="5F015A021300562C" modified="2025-10-08" version="1">MRWAVHASALFPLLHFFRPAGSAAIPRDDRCRETKVAILGAGVAGITAAQALSNASVTDFLIVERNDYIGGRVRHTQFGVNPKTKAPYTVEMGANWVQGLGSKGGPENPIWTLAKRYGLNNTFSNESSILTYDQNGYEDYTDVLGAYEKAYGVVEQDAGYILMGNLQDTSMRAGLSTAGWKPKKDMRMQAAEWWAWDLETAQTPEESGFLYGITGYNLTFYQFSEENNYVWDQRGYNAFVIGESQTFLSANDKRLLLNTTVKSLAYSDQGVTVKTQAGCIKADYAIATFSVGVLQNDAVTFDPPLPRWKREAIDQFQMGTYTKIFYQFNETFWDPNTQYFLYADPKVRGYYPVWQSLTGPGFLEGSNIIFVTLVGNEAYRVEQQPDEKTKDEGLAVLRSMFPDKRVPEPVTFYYPRWSFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1D0</accession>
    <name>A0ABR1X1D0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004186</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672119.1">
        <property type="nucleotide sequence ID" value="XM_066808501.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041561"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF112">
        <property type="entry name" value="RNA EXONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="6">
        <location>
            <begin position="410"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="29"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="471"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="614"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="471"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="637" mass="70649" checksum="65DCE6F241806766" modified="2025-10-08" version="1">MASSLGMLKSLPCPAGKSCTAFQCLFKHEDDPHAKTDDDDGTTTTDTGASDVPLAPSTNQEAPRKRQKVVSQAGKATDTPEKVPEPQVQAISPPLKHKKGPAMSTSARPEKPSPVMPAIEKTKAKDPKPAIAAVPKKTETLNARHLGKAPAKHDMRNKLLKLLHEHYVRLNTELKKETKGQGPEAALILTDQELIVKALDEEEHYAVKKLTIYNNAIKNRIMHYKKMKLAQWKEERLASIKKEYGTGEEPKQAPKPIETGLTPEQEVDFLHRLSIDLVTLQHFGYIATVPKDEDIEKAKKAVEASGNFEVCDRCTRRFAVFPGRREEDGALASNGPCVHHPGKAYYLDRTPGDRLSERTRKYRCCHQSFGDTNGCTTADNHVFKSTDPARLASIVNFVETPPNPNVPKDRAVSFDCEMGYTVYGMELIRITAVSWPAGEELLDVLVLPVGEYIDLNTRYSGVRPEDLAEAERWKPGDDHRPTIVPSTDDSPPQRKLKLVPSPQAARDLFFSLISPDTPVIAHGAENDLTAARIVHPTVVDTVLLYPHKRGLPIRNSLKYLMEAMLDRKIQVDDTVDKMQGHDSAEDARAAGDLVRLKVKTEWEGRKRRGWTIGANGVIQPPSEPEAWSIPGKKGKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1M1</accession>
    <name>A0ABR1X1M1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004253</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672186.1">
        <property type="nucleotide sequence ID" value="XM_066808568.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041628"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013700">
        <property type="entry name" value="AflR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF31">
        <property type="entry name" value="MONODICTYPHENONE CLUSTER TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08493">
        <property type="entry name" value="AflR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="15"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="360"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="419" mass="44882" checksum="055607548A405617" modified="2025-10-08" version="1">MASPAKPRQPRLRASCDGCFLAKVKCSKARPICSRCLACGIECRYSPSSRAGKPKADVSNSSHAHSSTEANDIPGMGDDKAMLYATPTAQCSEQMFRLDSGWATPPTSVDGSMSRNPSISTGLTLLGVDDRIMGEHDGMPAPPEMYASTMPWTPPTDLSCTQYGDVAVTAAHMPGAHVRSQSFDMTMPTPMSWPDPSTHDMMAYSQMPTPASMSSNYFPSPTATPSMRPAPTRHKSSSSTINGGSCTCFTACLQSLQALHNASSPATPPFDLVLSLNRKAVEGCAAMMACPKCMSRSGTHTAAMLLATVIGKITSFYKNASHTYFDTGSIAVNNGSPGGPLGFTLGVYQLNGEDGRWLELEILARELRKLEEVYARFREVCSDLSEDPEVSRAMLGYLGHTLGSTLDLVSHRKGDMTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1S3</accession>
    <name>A0ABR1X1S3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672252.1">
        <property type="nucleotide sequence ID" value="XM_066808634.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041694"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="191" mass="20277" checksum="32CC6E40CDB074C1" modified="2025-10-08" version="1">MVVPCTATSKVAVVTSAKPVTTTLTSAAPAKTTTGTCPIATPTGICQQPKNAKYGYDVSTPLGGINLPALTCNNVEAEHRVGRIFKLYTDEDTKKCVSFAAPKVADACSQACRTQYDQCVSVYAEGCRTKGNQPARPYHRRTGSSAPVAAAVSFVDSYDGAKTKCVQQMKDCLDINKNSVSDKCKKYGVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2S1</accession>
    <name>A0ABR1X2S1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672523.1">
        <property type="nucleotide sequence ID" value="XM_066808905.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041965"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37849">
        <property type="entry name" value="YALI0E11605P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37849:SF1">
        <property type="entry name" value="YALI0E11605P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="115" mass="12556" checksum="1F0F535E0B23FADF" modified="2025-10-08" version="1">MSMRVFSSGARGLSALSPVRATATRNFSASTRRLADATVLPARKPVGAFRGGLFGFLLGSTLAGGSVYTYVLQEYKASNELLTEDIYALQAACQRLSKYVRELEDKMDAAERKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2X9</accession>
    <name>A0ABR1X2X9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672583.1">
        <property type="nucleotide sequence ID" value="XM_066808965.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042025"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="63" mass="6745" checksum="642E8B14C3A16488" modified="2025-10-08" version="1">MRRPSGGDDGGPQRDFQVQFIALSTHELPRPRGLALLVNIGLPGWAAKAGKSEWMTSGSQEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3H5</accession>
    <name>A0ABR1X3H5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672856.1">
        <property type="nucleotide sequence ID" value="XM_066809238.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042298"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="21999" checksum="A653CB8C02A50893" modified="2025-10-08" version="1">MVNKIMGAFMAADGLFAITGAIMMGFSVTVLNTCFDPPTEGEGAARDLLYRRFPLQAGIANAVMVFVNFALTLPALATPARGLLKTAGYMIAINAVFSLIIGLDLWITTLKTKQEFSEIWISQTPEVQSLLQTRFQCCGYFNSTSPAFTNVFVDNIFTAVFAFVGIDVLLILATACLMKDRKERERFRHIDEKSGVRQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3W0</accession>
    <name>A0ABR1X3W0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">60S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005059</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672992.1">
        <property type="nucleotide sequence ID" value="XM_066809374.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042434"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00427">
        <property type="entry name" value="Ribosomal_L29_HIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_uL29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045059">
        <property type="entry name" value="Ribosomal_uL29_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8090098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14647" checksum="81DC71DF93D8EE68" modified="2025-10-08" version="1">MSTSKVKAGTLWSKNKDELVKQLGELKTELGQLRIQKIASSGTKLNRIHDLRKSIARVLTVINIKQRNQLRLFYKNKKYLPLNLRPKQTRAIRRRLSPEEKGAILEKTKKRNTHFPQRKYAVKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X810</accession>
    <name>A0ABR1X810_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bcrpn9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002018</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673629.1">
        <property type="nucleotide sequence ID" value="XM_066806333.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039393"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054179">
        <property type="entry name" value="PSD13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035298">
        <property type="entry name" value="PSMD13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040798">
        <property type="entry name" value="Rpn9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22037">
        <property type="entry name" value="PSD13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18261">
        <property type="entry name" value="Rpn9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="175"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="380" mass="43263" checksum="9A90E988C4CB08D7" modified="2025-10-08" version="1">MNVDTIADFLAEQRDEAPEELQGLIIQFEDCWERKLWHQLTDALIEFFNHPGSAKQRLPFYKVFILKFADKINQLKLVDLGLKAATQCRDTQERLSFLQDLAEKVDSEDSQDAHVYATVAGALTKLNLEDNEGARKDLDKAEKILEHFDSVETKVHAAFYRTNATYYQAEEDFASYYRNALLYLACIDLSSLSDKERKARAYDLGIAALISDSIYNFGELLQHPILGALTGDLSWLHDLLLAFNRGDLAAYEKLSNHVKSNDMLSDHQVEIRQKIYLAALTEAVFRRPPHQRAMSFEAIEADTKVKHNEIEHLVMKALSLGLVKGTIDEVDELVNFTWVQPRVLDMGQIASMSQRLGEWGENVNKLGNWIEATGQDIWAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X860</accession>
    <name>A0ABR1X860_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">C2H2 finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_002022</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673633.1">
        <property type="nucleotide sequence ID" value="XM_066806337.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039397"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8091661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="118" mass="13701" checksum="BF619173FB8BF259" modified="2025-10-08" version="1">MGIKNKRTLTKTRRHLRDLDQIKADLLSPRHLEQYKETKATDDLPDLGKWYCIECAKWFESERNMLFHQKGKPHKRRVKQMKEEPYTQREAEAAAGLGVCNEAPSKPAAADEDEAMMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8H8</accession>
    <name>A0ABR1X8H8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002132</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673743.1">
        <property type="nucleotide sequence ID" value="XM_066806447.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039507"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13738">
        <property type="entry name" value="Pyr_redox_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="587" mass="66544" checksum="DDCFA47926657428" modified="2025-10-08" version="1">MTTVALYPKLCPNSQFADISLADDSAIFDCIIVGAGLTGIIAAQRLLQAHPDTRLAILERDYCVGGVWSERRIYPSFWSQWTHDIAEFSDMPMERPPTEDCMNDLFRAKYTTKYLEDYVNKMSHPEKTLRDRILFNTQVQSIRKVNGQWEITCLDGNTRSQRSLSSSKLMMANGQSSVPNVPNFAGQEHFHGRIIHSMDFGQSDLIQNPSVEHIAVIGGGKSAADMVYEAAIAGKKVSWIIRKTGSGSLGTSAFAPIDLPTPYRNGVEASQTRIMASLQPSYLIPNRSWWTWLLHSTHLGAKLVGKIFAALDGTVRKYAGYRERKSDKGFEKLEYDNDIIWQNGTAGGCHFADFWPLVAEKVYVHRGSVKLLGGRELYLDDDDGTHFPCDAVLLGTGWKDGLEMFDERVRMELGLPFPKAMEKPEETAKWYKLVSEADEEILRRFVMLRHPPKHYHRYETRTPYRLYHTMAPLHDDSILFMNHIVAGAKLFAAVAYWDKAFRLPPLAEREADVARMIAWNKRRYLSNGELGDFAAFDSVPYVDGLLDEIGVTSHRNKGWLGNMFAPIMPADLGRVWCEYLAQRQINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X996</accession>
    <name>A0ABR1X996_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetracenomycin polyketide synthesis O-methyltransferase tcmP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673966.1">
        <property type="nucleotide sequence ID" value="XM_066806670.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039730"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE YKTD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619:SF2">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="306" mass="34858" checksum="870B9F92BF141C9E" modified="2025-10-08" version="1">MTPSLESQSTGLGERPKEKIRLKGVEETLFCTLLPKARDAERPNPVLGDPYASRLIESCDVDLTRSTFQAVVNRAMTFDRWCRDFLQKHKSEPLTVLYLGCGLDCRVHRVKPGPDVRWIDLDRPMVVDLRQRLIPQAPEGDYHMRILDITATGWMHDIPADRPTLIMAEGLFMYLTPELVESIIRELVEYFQEGEIFLDTVSNLYVKYTHHVELLKASGAKWKWGTDDAREVEKFHPRLRLLEHVRSADYMGKKAFGQSQVPLFGDDATGVFKMVLASFSSSNSAFGQNARFEFARPESESSAETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA41</accession>
    <name>A0ABR1XA41_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674306.1">
        <property type="nucleotide sequence ID" value="XM_066804533.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037593"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022085">
        <property type="entry name" value="OpdG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12311">
        <property type="entry name" value="DUF3632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="32801" checksum="29E912F548CE549C" modified="2025-10-08" version="1">MRQRAVPLFRPTRPLPLPKACHQIVQIHPGRGDAPPKQESIERVVVWHTFLDAAELMPYNHPYMAKLARLAADLRYSPKTGQSYGRQTREPRHLTTRAACAERNDFTAPLRDENLDEPARLDRDRRWINKNAFYANIYPLGWPEHADYLHDVLDLAFGPGDNGSKRSDPIWRDAHVSAAAQWILYNGQAIFQEVLNPADFPIMGAKPLRLSLAEWRHCKEGFRGVGDSEGEEGQGKEEVKGLAARAARLMDAVEESMMAVLGPAVAPRDTEEFIYMIARRMKYTLHKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB72</accession>
    <name>A0ABR1XB72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674682.1">
        <property type="nucleotide sequence ID" value="XM_066804909.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037969"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="756" mass="82687" checksum="2465E97706126375" modified="2025-10-08" version="1">MEGTAKSIGTLINAYLPGHPHHLSISATAQYALPANNSRPEEDIITQLQYMTYLHDVDRGVLFTRAEYDIIKEPEIEYKNALAAQTPRTDPNKPVTKLSLKDYKNRKNQPASAEGDAPKKSATSQSNSATANKSATEPAPGHKKHLEPPSVAREMGRDPEPRKAHPSLPPKPDIKRARSPSPEKKKRPSDTLDNDRAAKRAKLESPMPNGKASSLHSKSTTPQINDRPASHAKKASKDLKGSALVNGRSALSNSAKDSASPRPSSQVNGSQKSMNSSHGTPKKEKPFVPSLLSPLGFSADDYEITRPAAKKPADSKASKKPREDPDPSPKKDKVQDSAAPFALARVEASQKTTPTSSQKSNTSDSQSTARKGPAKSIKKDREDTIHVESKGSEKTEKKEVKREEDTKLVVKMKYPKRLAKTISRLLALPPKKADTAKRDMSEGIKKEEHAGRDRSVSVEPATTARKRPRMGPDINEPPAATKRPRTSDIAQPATPSKQSVTMQRVASSSSQAGTPGAVSTTPAPPTSSDRRYTPADLEKVGRLKKRCADYQGLGTRLKHAREKSLKPPPGGNAPPQMSHDERLHGMAMAIQIVLSYMVGFQALDESRDAERKARDPSHWKSIFPLLRLYRHECQSSGEVHALLLRLFSICQVWTGRAINSLPLDSNIARDMSQNVKDQETTWKMAEQARKKLDDPDGYGGGEVARLIDRLGPWSSPDEAAPVVLKVLRRAIRVRDGFTPVRELVEVANSMTNGARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBH6</accession>
    <name>A0ABR1XBH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitotic apparatus protein p62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674774.1">
        <property type="nucleotide sequence ID" value="XM_066805001.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038061"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42067:SF1">
        <property type="entry name" value="MITOTIC APPARATUS PROTEIN P62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42067">
        <property type="entry name" value="YALI0C15378P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58022">
        <property type="entry name" value="XRCC4, C-terminal oligomerization domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="219"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="152"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="43311" checksum="5C6593EF42E0E5BB" modified="2025-10-08" version="1">MTPSHILRLPCGDAESGNFVLEAKSNGSKPLDLLIRGTDGASAFETKTRHNRIKEFKAANAPCSEAEWEQILLAILVDPQGATRAQDIEIKVELSSDEEVTLHFRKNIQGIAQRLGTIKLKEFDETEDNPGISPFDWCIQILEDHEKVVQEVGATKALARELEQSVEELKGQLEDLLKAKEGDESVLLEKFRDLLNEKKLKIRQQQKLIESAEVDPEKLQNVGASQHTMRKAGGSRTSKRKIKDEPLSDEGSDGGFEKMDVDDQNSGPQRDSDTDERQTTDNDATESEPDNNETDAEEEEAPAEPAPKKSKPARSTRSRATKGSPAPSKPTRASTAAASRSTRASQKQSEEPAAVEAVDEMAAPPPVRTLPFKSKANKPAPAPVADDETESDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC79</accession>
    <name>A0ABR1XC79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mediator of RNA polymerase II transcription subunit 18</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Mediator complex subunit 18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">MED18</name>
        <name evidence="3" type="ORF">PG997_000996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mediator complex subunit 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675084.1">
        <property type="nucleotide sequence ID" value="XM_066805311.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038371"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019095">
        <property type="entry name" value="Mediator_Med18"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09637">
        <property type="entry name" value="Med18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0010">Activator</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU364150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="272" mass="31328" checksum="84B37A4FCB6D67BA" modified="2025-10-08" version="1">MYELSFHGTMFKADIDNARSILNGICDSQGLHTIKRVVYYAGPPQPHKKGLPNQEHVMLMPPPPPPPNKKPEPPRPHPAWPALCKELARSSYFLRLAYNVSPEKDFGSDVDVDLNLVPGTLQWFDFPDPPKGHPFTQRRKLEIPGQKNLPMVMADNNYEFDKELIEETWSFVKGEDFEIAFTRYFTLPERDVEPPTQVVRLPAWSDLAPLDPAEKWLVSIKSFAWEENNPEETKKAASQIMEEKLFFDRLFTFEAVDRRDLDTRVPPPGRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCR6</accession>
    <name>A0ABR1XCR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chitin synthase III catalytic subunit domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675268.1">
        <property type="nucleotide sequence ID" value="XM_066805495.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038555"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF1">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="299" mass="32169" checksum="3B1D2F7B73290803" modified="2025-10-08" version="1">MGSTDFGKFNAFCRDATLPICNLFSESHNQTGPWGGCKLEGIPLSGGRQLGNLGSILLCGIAIAVSVLLLLLSERKKAAVGRREMQLFLVGYIILEICEIFTVGEFPLNSTVRIAFTGIHIGMVIATTWILMLNGVVGYQVIDDGTPISMGLMALSGIVLLVGTGYIALDTGYDWTGTFQGSMDAAGGNRHIALYVLYQLAPLVFLVAFFVLEAILVLRVLGEVRPMAYLTGAALLFAIGQIFNYTISPYICNGTAGKIDGALFETLFTLLSVIMVWIFWSSITEDDWPIATGPATGYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE95</accession>
    <name>A0ABR1XE95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_001688</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675776.1">
        <property type="nucleotide sequence ID" value="XM_066806003.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039063"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF47">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="12">
        <location>
            <begin position="145"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8095003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="461" mass="51814" checksum="59202CC2896DEC32" modified="2025-10-08" version="1">MGHSSRLRRVFFVAVVFTETPVCPKSPLSDDVLVVLRTGATEAREKLPIHFQTVLTCIPDFIIYSDFEEDIAGHRLHDVLSEVGEGLRQSNPDFQLYNQLRAHGRDGLDYETLFGSGAGGATDNPGWKLDKWKFLPMVDRALRHRPGAKWFVFVEGDTYLVWQNLLEWLAKFDPGQPHYLGKHMYIGHVLFGHGGSGFALSNPAVRKVSQRWGEAQAEIEAYTAQEWAGDMVLGKVAKDVGIDMFWAFPHLQGDSPSTMDWNVSKLGREPWCYAPATFHHLNGGEYEALWAFEQRWLLDHRTSWTSPRFRDVIKAVVLPRLRERRDAWDNMATGAEYSTEAFAKLSEEDRRALSPAERQAPGSFEGCRAACESKPGCIQFSFSPGRCTTSTELRLGHAADAPCLEYSNAAAKCLRPAGPRVDSLSSSPEEFIHAGWIMSRVSDYVKLLDGSCVRISEEWVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ63</accession>
    <name>A0ABR1UQ63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6594 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_015288</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660487.1">
        <property type="nucleotide sequence ID" value="XM_066819602.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052662"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046529">
        <property type="entry name" value="DUF6594"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502:SF3">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20237">
        <property type="entry name" value="DUF6594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6594" evidence="3">
        <location>
            <begin position="76"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8061067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="357" mass="41380" checksum="161740CAFDB95C3C" modified="2025-10-08" version="1">MASPISGCPDLEKGHPHSQPSIAASEATVKQDQQVGTTTSTPSSTSNWWQWLKEKKTPDKTREPRHRKLNCKERSYRSVATFLDSDENFMIYRRFGYLHSRMLLRLQDRLRALEFKLDRCDNEDAAHETEKWLLMSRDKDEAACRTLMKEVPDIPTRTQILDEIEVFLGKYDDWVLKAQQMVSLNRPAERDYQSVESHMFSTKPLVDEEYRFIYQKEDLITLRDGREMALLDSLTERLLRTFHCPLLQKIFCTKRELEKTDDPDVYYYSKSRKDCFNTIILCMVLISLLVLPIFVLYSLLNDDPNGRSYTVSIGVLLVFVLVFSAALSLFTKARRHEIFAAAAGYAAVLVVFFGNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ85</accession>
    <name>A0ABR1UQ85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HET-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660502.1">
        <property type="nucleotide sequence ID" value="XM_066819617.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052677"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF82">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="35"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="266" mass="30896" checksum="50FB8F014604BA7E" modified="2025-10-08" version="1">MSPNKIRLVVINPGDWDSTISCCLLHHELDTNPKYIALSYAWGPTQVKKPIFVDGIELPVTVNLESALRHLRRQYEPLVIWIDAIAINQDDLAERSHQVGLMRRIYQQASRVIVWLGDSVRHRTMGPPRRSQPPLRATFYGDARDDEQVADFVRRWAVPCPSAKYTPLDVFCFIRMLMLPQHEGYRLMQLHLQQLPEIAEALRVMLMSQWWTRMWVFQEVIVAPEVRFQYAGVEAPLDMFTMAAFCLTNHQYLSDLPSDATKVLHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTI4</accession>
    <name>A0ABR1UTI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Efflux pump dep3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660850.1">
        <property type="nucleotide sequence ID" value="XM_066818662.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051722"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="80" mass="8867" checksum="5B93213C2F0B8494" modified="2025-10-08" version="1">MALQFRGTVYAWDSASEIVLWVFSGVLLIAFVLSHIFHPFVDAGDRYYPAYMLRNLKLGVLQLATFAASGAVYVCMYGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTW4</accession>
    <name>A0ABR1UTW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660736.1">
        <property type="nucleotide sequence ID" value="XM_066818548.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051608"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF11">
        <property type="entry name" value="ZINC-CONTAINING ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="28073" checksum="754A2D7F19499317" modified="2025-10-08" version="1">MHAAQVLNWSDGPRYLSVAAPPPPTADELQLRVLAAGAHNVVRSRAAGTHYSAKTLPHTLGMDCVARDDAAGQLYYVTSMADTFGTFAEYINVPKEGSTLVVPLPESADPVAIAGSVNPAFSSWMAITARTTDLPKDWTCLILGATSASGRLAVHAAKALGAKKVVGAARSEATLKTVDGLDGYVVFDAAEKDPQLLNAVGADVVLDYVYGDVAERFFAHFRNPGKPVQYVQIGVLSRRDGVALPSGILRSTDLTIRGPAAAVGGWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV97</accession>
    <name>A0ABR1UV97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucanase</fullName>
            <ecNumber evidence="7">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_014914</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661416.1">
        <property type="nucleotide sequence ID" value="XM_066819228.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052288"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001524">
        <property type="entry name" value="Glyco_hydro_6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF2">
        <property type="entry name" value="GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001100">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00655">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 7" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044958213" description="Glucanase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8062817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="382" mass="41275" checksum="6C79BE40CE7646EF" modified="2025-10-08" version="1">MKTTTTSLLALATAAAALPSPVHKRACDSAVKLDASSNVFEQYTLHANSFYRGEVEAAIANLKDTSLAGAAKKVGEVGSFLWLDTIANIEKLNTELAAGIPCENIFGLVIYDLPGRDCAAKASNGELAVGEIDRYKTEYIDGGNRWDSQGEPQPSLCPHHRARLLPNLVTNIDEKACQDSEAGYEEGVEYALKQLNLDNVVMYIDAGHGGWLGWNDNLKPGAEGLAKGLQGRWLPEPAKQGTRDETPGEFSDASDAQWNKAQNEKLYTEMFGAELKSAGMPNHAIVDTGRNAVTGLREEWGNWCNVNGAGFGVRPTADTGSELVDAFVWGKPGGESDGTSDTSATRYDSFCGKPDAFKPSPEAGQWNQEYFEMLLKNAEPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWX3</accession>
    <name>A0ABR1UWX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014653</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661155.1">
        <property type="nucleotide sequence ID" value="XM_066818967.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052027"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF10">
        <property type="entry name" value="COCE_NOND FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="2">
        <location>
            <begin position="329"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="596" mass="66964" checksum="B97C040A9C964894" modified="2025-10-08" version="1">MPDPVQVATRRIETPKVGENGYVGFTPGKTEVLKAGAIPFDAKPITSDIRIDHDVEVVVRDGARLYMDVYRPAGSSKTEPVPAVLSWSFYGKKYSALDMLPICTWHCCVPRSDLSGLEKFEGLDPAYWCPRGYAIVSVDTRGAGHSDGQICVMGTQDAEDGYDVVEAVARMDWCNGRVGMAGNSALAIAQWFIAAQQPPSLAAIAPWEGMGDMYREQFCRGGWFSMSNFDLIAKAIVRGQPDSGLEHFAEMYRRSPTQNAYWKQKRVDMTKIKCPAYIRGSDVSSIHTMGCIRGWLEIPHDDKWIHWSSKQEWYELYSEPESMDELSVFFDRYLRGIENRWETKTPKVRWSALQFGNREPIDNIVIDGFPVKGTDYRELFCQPDGRLAPEKAASATSISYNSEDRASFAEFTYTFTEPARLIGLPKAIVYMSCDSRDDFTAFTILRKKDKDGKDLMHLNFPMHATPVKAIEEIPEKDQASLNLHLGSMGILRASQRAIDESKSIHPQFPFHPHEKQEKIPPGTIVKLEIGIWAMGVDFDAGESISLRVGGQFPSIAEYTSFSGPRPEHEQNRGEHKVHFGGEYPSSVILPFTPLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1G4</accession>
    <name>A0ABR1V1G4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661788.1">
        <property type="nucleotide sequence ID" value="XM_066816096.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049156"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF30">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="167"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="169"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="33159" checksum="8BC7781016A25456" modified="2025-10-08" version="1">MSSYLTLDPSWAAPSSCLASTAYYYMVVRTYSAGIIFSEMFGAPTPLLMSADPTGPCIPPGFTTETPYMTDGPCPTGYSRLVRPAPHFRVLPQAPPSGAFKFACHGETYGCLATANKGDVWTGTRTDIALTPNTQAPETHTAYPGESLWAWGIKFIRRWKALLTTYDPKTPTATESPTSTAKETGATATGPVATVPTASITNFESTSPPRSTAVEPESVQSTPSQISPGATAGITVGAMAGALVLALVAWLLYRRKRRQRQPAVQQHDPQYHPTATCSPQEYYNAQPPYPQSKAELGPGGERYMPAELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V277</accession>
    <name>A0ABR1V277_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cleft lip and palate transmembrane protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012043</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLPTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662050.1">
        <property type="nucleotide sequence ID" value="XM_066816358.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049418"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008429">
        <property type="entry name" value="CLPTM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347">
        <property type="entry name" value="CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347:SF0">
        <property type="entry name" value="LIPID SCRAMBLASE CLPTM1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05602">
        <property type="entry name" value="CLPTM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="512"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="655" mass="73799" checksum="4F1721026A0E8CF7" modified="2025-10-08" version="1">MPEGNVAGRPAQEEQGGGQSMVYKILQGVAIYYGMNMLMKQFMPKPQTAEVKDADGHVVKVAANTGNIPPFQMRPNQLDEGAVYSSLPERVAPIWSTDSSLDVVVALSDSHVPLPMPKIPEQYLVLSEKEFKLGNYSDKRVVEATFDVPVAVQNNGTLWGHFYFGLTGSILDPHQQGFDPATAIHFAYPLTQYVPKKKAVKTRNLLEAKEEPVEEVEEDIAPGPIIASYYHPNASLSFIPDSGIINFPQSSVAVRQFLNLEVTGARDGTGKNGWYYPILFMNSFWQLKSHMMVLNETVKTLPIRIDLDNMRNWKFNLMASVELNAREQARQAAFGTPLPGGADGSEIEMIKEIFLDTNPWLLGITGVVSIFHMVLEMLAFGSDIAHYRKKKDNVGISVRSILANVFMQTVIFLYLIDNSQNTSWMILGSQGIGILIEFWKITTVVNVRVRPAPPGSWFPYAINFEDKHKLSETEEKTKEYDEIAFKYMYMAGIPLLIAYAIYSLYYDTHKSWYSYVITSLVGSVYAYGFLMMVPSLYINYRLKSVAHMPGKAMMYKFLNTFIDDLFAFTIKMPFLHRMATFRDDIIFFVYIYQRWAYKIDYTRVNEFGQGGDDEEEEEAKKADVKSLPNLDAAAEVVGGEAKATGANVGKATKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V295</accession>
    <name>A0ABR1V295_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662062.1">
        <property type="nucleotide sequence ID" value="XM_066816370.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049430"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="340" mass="37383" checksum="4754E70FAC286E0C" modified="2025-10-08" version="1">MPLFELSPFQFVVSQWTPLPYPATDCTDKVVIVTGGNVGLGLEAARHFTRLNAAKVILACRNTEKGDAAKADIESSTPNRQGAVEVWPLDLASFGSVRDFCRRADEQLGRLDVLLANASVLHTRFAEREGYEETLTVNVLSTFLLALLLLPALRRTAARFNTAPHLTVVSSDAHAVANFRCRDSPAVLEALRGDADMLSRYGDTKLLQLLLTRALAKALDGGESEPESESTAKKQPRVILNTLNPGLCRSELFRHAPWPATWVLYISMRLFARTAEMGSRNLVAAATAPEDTHGKYLSDCKVWEPSRFVRSPDGANVQRRVFAELLEVLEKIEPGVTANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2B9</accession>
    <name>A0ABR1V2B9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cyclin-dependent kinase</fullName>
            <ecNumber evidence="1">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_012088</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662094.1">
        <property type="nucleotide sequence ID" value="XM_066816402.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049462"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07840">
        <property type="entry name" value="STKc_CDK9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF546">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="292"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="245"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="591"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="187"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="595"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8065341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="650" mass="74322" checksum="B6CBD519D66B1CCD" modified="2025-10-08" version="1">MAHLHHSHHTMEWPAAVGVPSSNTRQMTSVRRHRRAHKLNTTKDSHHPNHPQGQLPAVVSRVVAFVEVASARLVEVVHGVMVSLLRPSMLQRVRLLVAIFLATPVKTRRNKPVHIMQARLIPTQLPITMSIRAKQALHGHFTILTMKMRALIGWTIPSRCHHQLVLPRRDRPLQHLLPALNSALHSSPPPRPRPLPPNPRFRRNLVRRLLEGINLLMTEIIEIIEIEIFPVARLLSLLPRERDPTISAADSSRNHSSNARLSPPYKKIRRPKPRPQLPSEHVRAESVYFRKPGNESVVGSGTYGKVFKGTNVYTKKLVALKKIRMEGERDGFPVTAVREIKLLQSLKHENIVNLMEVMVEDNSCYMVFEYLSHDLTGLLNHPSYKLDPAEKKHMAKQLFEGLDYLHGRGDGILKLADFGLARFYAKHHRLDYTNRVITIWYRSPELLLGETQYTAAVDVWSAACVMVEIFTRHAIFPGDGTEINQLDKIYAILGTPNKVEWPDLTKMEWFELLRPNYRKPNVFAEKYKERVPAAAFDLLTSMFHYDPARRPTAAEVLEHAYFTTEQPPPRQATALADIQGDWHEFESKALRRAKEKQEREARQAAREVSQREKDKKRPIEVQDARKTKRPHLEGQPPVGGDVAAGEAMVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2K5</accession>
    <name>A0ABR1V2K5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012172</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662178.1">
        <property type="nucleotide sequence ID" value="XM_066816486.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049546"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF72">
        <property type="entry name" value="OSMOSENSING HISTIDINE PROTEIN KINASE SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="374"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="802"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8065425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="938" mass="103855" checksum="343BD05DBD953F19" modified="2025-10-08" version="1">MGIPHSSFSYTTNLLRQPIPQRPLRVDAPLDVERAHLPLKPFDRDLHEEHFGGSDAPSSPDPPSGHNERYLAPYLTPNESSRLAAYWYHTRLIEQDELLLAKIDTLVNGLQKAIGWGYAIAGLLSESTFTRTFGSVFMVPDMSQDWRFKNAPQVEALGLKSYAGTQLRLMAEDGGDVALGSLCVASDYQQEPLSSDQKDLLVRFAELISASIASHTRQRRLKRRQEMNEMLSTFRSSIGDDHHETAALGIIQQAYPDAQVSIQSTSDGKIDLVGRPSIAYTDISEGVWEDSEHIESIIQSSNFKDLQSAQTVRAIVARCGTSDKYIVVASNDVQHVLDDFDAWFVSKIAEITATTIQNRLLQQALHARETFIRGITHQLRTPIHGVLGSVELLSEELTAMTLAGSPPVNWGESRHALSLWENVATIRNSGQELMTTVNSIIKHNVWTESTATKVQLSPYSLVSLERDIIGDITSYLQRAELQGVSIDFIEDLPQGGHIMLTTDARLLTECLQQLLMNAIHAVSDVPAGTVSLTVHASSEPPNLTIDIVDNGIGIAEENYTKIFDPYEKINPHKSGAGLGLTLASKTANLLGGSVKLVSSALGTGSHFRFELSDPVLEFVKEENPETSHEETQEPHTFHDIRNGSSFDHLVSRTVRHLEEKGLKRSDAASARYIVTDANHHEVACIQLLYPRSVVLWLSSMDASREAWMKERQMQRRIEVHGPLYRLKLDETLRQADLLCSAISPGTPKDLEVIEKAAAIPLVSMIQSQASDNALVPEIPPVVEIPEAEPGRFSGYCHQLKLRALLVDDNTINLKILQNFCKRRKIPYVTAEDGNQAQEHFVKAAESEEPITLVLMDLQMPNCDGIEATAAIRAYEEKHGSCKSLILMVTGQDSEMDKINSEKAGADEFLVKPVGPRVLDKYISACYSFYEPAGKVLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V334</accession>
    <name>A0ABR1V334_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS9m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">37S ribosomal protein S9, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012109</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662115.1">
        <property type="nucleotide sequence ID" value="XM_066816423.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049483"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_uS9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001099">
        <property type="entry name" value="PRK00132.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="324" mass="36273" checksum="3E0BA2C34E2BC018" modified="2025-10-08" version="1">MSSLRTGFRCLRDIRQTGKVAATAQWQPTSKASLAYRPKQAINATRSITTTAPRLAETTTTEIIPSDLEPADQDQSAVVQVPYARAVPISPSYFSRKPIFNDAFVIVQDLARKYARLPIIPRDKVTPTAWRTKEQYRLAVGEHVKGRDYATCMKLAKRLNQIHPDLMPEEVTAGLLPFKREVNYYLNQPKIQPIDQYGRSHGVGKRKSSVARAWVVEGTGEVLVNGKPLSEAFGRVHDRESAVWGMKLTERLDKYNVWAMVSGGGTTGQAEALALAIAKALCVHEPALKNPLRRAGCITRDPRKVERKKHGHVKARKMPTWVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V357</accession>
    <name>A0ABR1V357_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662377.1">
        <property type="nucleotide sequence ID" value="XM_066816685.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049745"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="169"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="360" mass="38704" checksum="F7827945A94841E5" modified="2025-10-08" version="1">MAAATPVIPIIDISTEGSGELDVAKALVDAAAEHGFVYIKNMGKDITAQQISNAFDLSRAVFASPIEEKQKCTIQKNNQGWSGMHTETLDPSSQRVGDYKEAFNFGPFTPAHEAQQPLPNTLAAAQVTEIAQFRGACHALCERLLHLFGLGLGVTPPDFFAASHAPDKPSGSILRFLYYPAPAAVSAASSVEAGEVRAGAHSDYGSVTLLFRLRGQAGLEILTRAGTWEPVPVCPPGTEDDPAPPILVNIGDLLSYWTNGLLRSTVHRVTFEGDGSGGKKVAGESNSEPRYSLVYFCHPTNDTQLTAVPSERVKCFKGGLAEANGGNPYAERKVLTADEHLKMRLQATYLQMYEKDDKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3D6</accession>
    <name>A0ABR1V3D6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Multiple myeloma tumor-associated protein 2-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662431.1">
        <property type="nucleotide sequence ID" value="XM_066816739.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049799"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019315">
        <property type="entry name" value="MMTA2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039207">
        <property type="entry name" value="MMTAG2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14580:SF0">
        <property type="entry name" value="MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14580">
        <property type="entry name" value="MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10159">
        <property type="entry name" value="MMtag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Multiple myeloma tumor-associated protein 2-like N-terminal" evidence="2">
        <location>
            <begin position="11"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="257" mass="29340" checksum="2E0048355E250F78" modified="2025-10-08" version="1">MDLVSSIRKSGSRGGVNFSWDEVANSNHRENYLGHSLKAPVGRWQKGRDLNWYAKSDATGAPTDETEEDRTERERREEIKRVKEAEEDAIAKALGLPPPVRNQSGANSVEVSKPRLGPEEEKAATPADDAAEPRSSHRRHRDPETHHRRRHRSRSRSREREHDRRRHRSPRERGGRPSDERDRHGDGGHRRTADRDADREREARRSRGKRYEEKRRLVPGTPRGMAKQGGGPGLEARGRVEGVEVLLTMSDEPNVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3T1</accession>
    <name>A0ABR1V3T1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662602.1">
        <property type="nucleotide sequence ID" value="XM_066816910.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049970"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045279867" description="Small secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="15758" checksum="947A512C1422AE88" modified="2025-10-08" version="1">MKTFNTIAIAATLATSAAAMPPAVLEETPCTSGTPTTTAGYPISYFHATPTQFADKTYQPEANWAGSHILGTYTYGMPLPLETGFAYAQYKCQFKCNSFGGSSFFVKYAGVDETEGALCTCYSDLMDPDTFVADDQAMVGAWNSLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4N2</accession>
    <name>A0ABR1V4N2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Riboflavine-aldehyde-forming enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012619</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662625.1">
        <property type="nucleotide sequence ID" value="XM_066816933.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049993"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047167914" evidence="2">
        <location>
            <begin position="21"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="128" mass="13073" checksum="A364A4959D02F8E9" modified="2025-10-08" version="1">MSSFTNFIMTTLCAAGLAAALPMNAPAAVVAPRGSSGDMTYYNPGLGSCGLTNADGDAVVALSPSQYAEHPDACGKKIVINYGGKTATATVVDKCPGCNTDSIDVSPSVFQSLESLDAGRVQVSWSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4T3</accession>
    <name>A0ABR1V4T3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662941.1">
        <property type="nucleotide sequence ID" value="XM_066817249.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050309"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="186" mass="22497" checksum="2F30C60937A138F9" modified="2025-10-08" version="1">MNLLPDLNRRQREHISLLTKFYRMPVLLHFAEILPYHKYFHLRDPEPLVLDAYLFCLIYTVGRFIDKHAVLPRRFGFMPLYNLADSFDCKFDSLSCRDRIFHLYEDGTWEEEMDPFLNPDEYFAAKAKAEAQPDRKPHRTVKLLYHNYDTPKSGRVSYRNLYYYEVLNAFTEQEEKYTDEKYIDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5T2</accession>
    <name>A0ABR1V5T2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663325.1">
        <property type="nucleotide sequence ID" value="XM_066817633.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050693"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="492"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="62684" checksum="9503C87373BED88D" modified="2025-10-08" version="1">MIDSANQRYSSDSLAAAFVAANCMTLALLSIHYLVAYKPRRDAMDSVVLEWPRRCFRQLTASVLGTPAGKESSGFSGIAPSMEGWLRMCLVNVADMQAILGFKLLHELYEAVDAEISAAQWQFLMHLAWFPAIACMCSISVLSPPSATNGRGDAHEWPRLGRAVALAALLGSMLVGTAPTFFFNWEYGRQEASAAALGTDARRFLFDLAGELRRFRGGEGSAASLSETHGFQLAAFSVVALMSVAILVLAKAISAPSKEEEKKECPSQQTKSSGTTVSRWLGVQRGGIHLEDLEDVESSLSLVDARPNPRTFGGILSDAAVFFVRFNLDLLTSRLAEIFLLLVLLAWGVARLYGSMRKSEGQIPNGQALWSFSQQLPLALWVVPFVVATNSYLLPVNVSRPSSEYQCIGQSADEKETASQPITSGQKDGDDESAPAEENNTPSYPTPWMGVSLVCGSGLLLVMTFAFFAATFNMMMGFEPQFLVSEALFTRIGVIWVFFLGYPCACFATGLVAYTMERCWIRKRGGGMLPDATAMMDQVGGDEFSKWRVRDYLLLLVIGGAAHAFSVAVLLVMSMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V690</accession>
    <name>A0ABR1V690_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UV-endonuclease UvdE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013466</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663472.1">
        <property type="nucleotide sequence ID" value="XM_066817780.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050840"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004601">
        <property type="entry name" value="UvdE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00629">
        <property type="entry name" value="uvde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31290">
        <property type="entry name" value="UV-DAMAGE ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31290:SF5">
        <property type="entry name" value="UV-DAMAGE ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03851">
        <property type="entry name" value="UvdE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0228">DNA excision</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="124"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="551"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="551"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="567"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="580"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="638"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="647" mass="73771" checksum="662E3505E37898AE" modified="2025-10-08" version="1">MVSKRKKSEMALLQQDVLPNQHMDSAPRPDFAPRRSARAKNAAAAQHEISKTDHEQDGSKNNGQMRRRREDVEEAMHDLQDMEAQLRGVVKRQKLAVKSSSVMSNPVDMGKAVFTPKAIKGGSETLQSAEHWDTHAKKPTTKPPTKRKTAKTPSIKEEAVGAEEASGMTQEDPEEPAEPEAEDINEIKLEGARPPPVNSDYLPLPWKGRLGYACLNTYLRQTVPPVFSSRTCRIASIIEHRHPLADPSLPEHATKNRPDKDQPADVARGQKFVEDLGLANARDVIKMLRWNDKYGIKFMRLSSEMFPFASHEEYGYKLAPFASEVLAAVGQVAGELGHRLTTHPGQFTQLGSPRTEVVRNAVRDLEYHNELLSLLRLPEQQNKDAVMILHMGGMFGDKEATLDRFRANYAKLSPEIKARLVLENDDVCYSVHELLPICEELNIPMVLDFHHHNIIFDKEQLREGTKDIMELFPRIKATWDRKGITQKMHYSEPCSEAITGRQRRKHRPRVLTLPPCANDMDLMIEAKDKEQAVFELMRTYRLPGWDSFHDVVPYERDDDNRPVPKPKTPKKKRKGKKAAEEEEDEDVDTVDGEEEPMRRVIPEEEVGMGGPENRVFWPMGMEEWLRPKKREVKKKTPPKKDAEQDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6B4</accession>
    <name>A0ABR1V6B4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glc8 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663473.1">
        <property type="nucleotide sequence ID" value="XM_066817781.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050841"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007062">
        <property type="entry name" value="PPI-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398:SF20">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398">
        <property type="entry name" value="PROTEIN PHOSPHATASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04979">
        <property type="entry name" value="IPP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="26593" checksum="9C1C90B0400A9817" modified="2025-10-08" version="1">MATVETSPRVVHSPPPTAAAQRPRGILKNSYQKSPPTSPIKEKDITEKELTIVNTQANAGHRRSSSAASRPSGSRRQSSRTPSATAGDDATDENQQRLKWDEANLYLTEQERTSTMKITEPKTPYAKQYDPAEDPDDEDMEMGDGGGRGEDIPGLSLGEPEEEVPEDEFGPPGSRKTSKVHEREKHKRFEQLRKKHYEMREAVGLLGHPEIVDEDADDDGGSSDERAVPPMPKLPPGINGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7C3</accession>
    <name>A0ABR1V7C3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arginosuccinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013843</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663849.1">
        <property type="nucleotide sequence ID" value="XM_066818157.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051217"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814:SF1">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00145">
        <property type="entry name" value="ARGSUCLYASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="3">
        <location>
            <begin position="18"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Argininosuccinate lyase C-terminal" evidence="4">
        <location>
            <begin position="372"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00032749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8067096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="464" mass="52066" checksum="B61E0C617AB35ED9" modified="2025-10-08" version="1">MAEKRRMPRQLVCSGAAGAIDPLMHKYNASIGYDKALYKEDILGSIAFARANSKAGIISEDEFQAIERGLLQVMEEWKQGTFAIMPNDEDIHTANERRLGEVIGKDTAGKLHTGRSRNEQVVCDMRMWLRDRIREIDSQLVAFLKVIVTRAESELDYIMPGYTHLQRAQPVRWSQWLMSHAAAFKQDLERLRQVFERVNLSPLGCGALAGNPFRIDRNMIAEELGFSGITMNSMNTSAERDFLMEFLVWNSIFTNHVSRWAEDLIIYSTSEFGFLRLADAYSTGSSLMPNKHNGDSLELLRGKSGRAFGQMAGLMMTVKSLPSCYNKDLQEGWEPMLDSVQTVSDSLGIANGVVATLTVRPERMEAALDKTMLATDVAEWLVRKGCPFREAHHISGRVVALSEKQEISMDKLTLEQLQAIDSRFTADIAEAFEYETSVEAKSSQGGTSRSSVLEQIQILRAMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7H1</accession>
    <name>A0ABR1V7H1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UFSP1/2/DUB catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013889</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663895.1">
        <property type="nucleotide sequence ID" value="XM_066818203.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051263"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012462">
        <property type="entry name" value="UFSP1/2_DUB_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07910">
        <property type="entry name" value="Peptidase_C78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UFSP1/2/DUB catalytic" evidence="3">
        <location>
            <begin position="240"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8067142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="476" mass="53544" checksum="873EC59B87BAA823" modified="2025-10-08" version="1">MAADSLKCPFLCGFHTPDEYDIYLHMETQHSEGKSPFAVDEDQHQEAIKHHDKNDDNVASSIEHSVEEEQFAECPIESCGEVITLAEYDDHIELHNLEEASGAAAAGSPYPEQEAATASTRSRHGDGSSKQSNSVQQWKQILQMPDANGHKRRSPEFEAAEERPRKRLGVSGPDDGKPTASLRLKPELTNRRLQKAELGKYAHEDRMPDWLVTLLKKEGQVVETGVIGVLEQLLESNPTTKYAYLCHPCVQHVSKLKKEGGFCGYRNIQMLSSYIVGTKPLGAEHFRGKLPSIFRIQDWIERAWDLGINSQGRIETGGVKGTRKYIGTPEAQAMFLSLDMAVEAQGFKDQQPIIAERKLLEHVQAYFEAGDIDPARKVRTTSLPPIYFQHRGHSLTIVGLEKRSNGSAELLVFDPMFRDPQSITKLIGRALSHKTSPDKSLSLYRRGNKYLKKYHEFELLKLVFSVSFSFSIPWNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8P9</accession>
    <name>A0ABR1V8P9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cholesterol oxidase</fullName>
            <ecNumber evidence="13">1.1.3.6</ecNumber>
            <ecNumber evidence="11">5.3.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Cholesterol isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_013095</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="12">Steroid metabolism; cholesterol degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.6" evidence="13"/>
    <dbReference type="EC" id="5.3.3.1" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663101.1">
        <property type="nucleotide sequence ID" value="XM_066817409.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050469"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052542">
        <property type="entry name" value="Cholesterol_Oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47470">
        <property type="entry name" value="CHOLESTEROL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47470:SF1">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8" id="KW-1207">Sterol metabolism</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="17">
        <location>
            <begin position="165"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="18">
        <location>
            <begin position="623"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8066348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1371" mass="151820" checksum="472450F432021972" modified="2025-10-08" version="1">MAPGTLERAETEPMPTTNGTGHGNGHAAADTNGFRKRFVNINGTNGTRTAQASPDSAAVSRPSSSRNDSSTTNEQEASSSARRRPYEPHPSPRGSHRIKSFGVHQDDAGGPSGAYARIRSWGDERKSASPLELMRSSYDCVVIGSGYGGGVAASRMARTGESVCVLERGREHWPGEYPSDTDDALGQVHYSGQFSPGWLPKKVVNGGDPTGMYHLIFGNGQNAMVGNGLGGTSLINANVYLEVDDETLQQEQWPEEIRSDPSTLGPYFQMAEEMLEPKEYPADWPVLPKLELLKKQAEHLGMSDKFRRVRQTTRFQNGPNRAGVEMSPSALTGQDATGLNDGSKNTTLVTYVADAWNWGAEIFCESEVRYIAKAPDREGYIIYFAWHGRNRGHFKANLHGDLMWVHAKRAVFLGAGAIGSTEILLRSRQMGLDMSDQIGQNMSGNGDIFAFGYNTDHEVNGIGRSFPSPYHPVGPCITGIIDNRHGHKNPLDGYVIEEGAVPKALSPFLQAMLELLPGSIRASDQSLIDRVRGNLARVGSLFLGPYFRQGAIERTQTYLVMSHDSNQAVLTLKDDKPVLEFLGVGRSDHVKQLNEVLAKATRAAGGTFVHNPFYALMGQQELTVHPIGGACMASDGTGKTGVVNHRGQIFTGQGKETYEGLIVTDAAVIPTALGANPFATITALAERSVDLYAKSRKLMVDTRRNGILDLFGSPRFAGDHLRTNETDSDDEDASISSARTVIKTAERLNDAGFGFTEVMSGFIHYDDWKQDASGLDTYELAARIAESRCESARFFLSVQSFNTRSIVNDPDHRAMLTGTFSCPTIPGSPFMVQRGGFNLFKQFLDAPGTRNMVYNFDMRGVDGTVLHFRGYKVVNSSVALSPVQFWKATSTLYVTITRPYSDDESEYEEGPDDTNNRGAIVAKGIMRIQPADFASQILTMTPTGSGLWRKAISATSFLTYFTRKSMSLFLAPLTPLQYPTQSYQGFVNETVPSVTYKIVAEDGVTTRMHMWEPTNIIGEPKNLFMIPGASVDHQIYALPTIRYNAVNYFTRAGYRVFIPVHRIGALMVAQNNWTTYDARLDLRACLEQIRKEYGTGKIYAIAHCMGSVALSTGLLDGRIPASWLAGVTCSQVFMNPMWNFMNMIKIMAAPLPLDRVYKAIAGNWFSCSTGQDDSYIQKALNELLRLWPNERKELCNNACCHRVTFTYGRCWNHENLNEATHRQIDRFFGGVNMTLLHLLMKQGTEGGVMANGPLFERLDTPDNIQRLRDLPFYLFVGGDNAVLSPTATERTYEVLCDAFGTRDTRDGKGLQYKRRVVPNYGHLDCWMGRNAWRDVYPFVRKEVDDIMRGEDYVFEEPDDQFKRMVDAGMMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9D1</accession>
    <name>A0ABR1V9D1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663326.1">
        <property type="nucleotide sequence ID" value="XM_066817634.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050694"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="2">
        <location>
            <begin position="98"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="259" mass="28477" checksum="7C9C63C5C9D759D9" modified="2025-10-08" version="1">MLEHQPPKMGWSALPSELRAMVMGRVTRHARIGSLASVCREWQVAFAYAISKLFSILHTWDASAVTQGIAHGIELDLKITFPSDPDDLTGRVRSPRSRSRPIPEGPAASRPKSQTLKALVAVGLFDAHDFLNYCRPGSAVAPGAWGRLEVLWLTSGFLVPGDENIRRLEAVLKAAAKASSGMLSLQAMQILTARDMNRQVGSFAYAQSRCGTATVTWKATWQYSLGECVREAWMECADYKRVTLGSKEDTRSILKGKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHS9</accession>
    <name>A0ABR1VHS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664580.1">
        <property type="nucleotide sequence ID" value="XM_066815290.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048350"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00195">
        <property type="entry name" value="UBCc_UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="221"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="773" mass="86219" checksum="E327A0477A7E65AD" modified="2025-10-08" version="1">MAESAPSNNLRATQMRQRLLLDIDELIRKPYPNIHLHVGENLDQLCLVLSPPGWQRMHLNIDWLDQFPMRPPRIQMDTNVRHPNVFGSYICATILNRDDYYTPAYTLKGIAIQLLSFFGSDKIQQDYGGEAVDLESYRTGSQDCYHVPFAACQRCGFEEKALKGDDLDVRCRDQSGSLQTRQRTAIEVVASHNFWAPIGTTPDTEKMPVQAIDRSETTDGPFAINELPNELLLQVLESIEDFEDLTNLAKAWPRVSALITEHNVIRQRELQCFVAKKTYRDVKLGVGVSTTNGLASEFDLLSQQAFALPTRKSVQNIPFTRWLPLPISPRHWHSVRTNAQTSLSVLKEHVKLQNPTNAQVLYAFMTDIVVKLNLVNLDNDNGNEKKQTETEYYYGSQDRNCSTLEHASEKAIESYFHLFHLLVCLATESPEIVTQANTLLKSFLGGKRDKSHCPNLGHLLVALLVSDVPVTDELRRAIITEAITRNVVWLLSPNESQRRRYPNNRDNTKKTYPELAYLEPDAVSAYRLDKTFQGTRTSYRLLMFSELFRRIARPSKSSSSSPSLAQIRDDLFRRHGAPSPGAAAHLASEVRRLHSINNFPTFLREMGMSENQIPTPAHFTTVLRSTVAASMDRGYSRWALAQSDALALRLRKGVDPGVGVRPEFADMVGEAPYLPHIELTNVNFFPGNNGTARRGRGGNKRDTVIGGGRGSLPPQGVAWPRRSAEAALGSSGRANGDAVTWTPVGSGTGRGNNNNGGGSPRGNRRGGRGVPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI69</accession>
    <name>A0ABR1VI69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664390.1">
        <property type="nucleotide sequence ID" value="XM_066815100.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048160"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="3">
        <location>
            <begin position="202"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="556" mass="60020" checksum="1D58FCECBEBC583B" modified="2025-10-08" version="1">MSTRSVLAWSAVLVALAAILARDRFFFFFSADPVCRTILSDAAWPNITAWNNLNETVGGKLIATVPIAAPCHKTLNGAPNDLYDEERCAVLRDTWFLPETHLESPSSPMSYLFSNDTCNPWLGPDTRCTTGTDAVYVINATEVSDIVEGVRFATENNIRLVIRNTGHDYLGKSTGAHSMSIWMHSFKSMDLQVRRITQPGGGWGNCPTVALAGGFIQGGGHGPLASRYGLAADTVLEMEVVTPTGEFVIASPKENTDLFWALRGGGGGTFGVVTSATVKAFPDTYGSTASMMVANTGTNADALYSAIGGFIQKALPGLVDAGAFVVWIAAPFGFMISPAVAPGLTSTELDKLMQPMVDILKGAGLEYQYASAQHKTFLDSFESYSQATSWNVSDYNVGGRLIPRSLALERTDELVGAIRHISTTAFMSGVSYNVARGVAAAGDVAVHPYFRETLFGLALGTPVNYTDWGATLAGQGRITHDLIPTLERLTPEGGAAYLNEANFEQGDFQRTMYGDHYERLLGIKRKYDPKSIMYARTAVGSEEWEERGDGRLCRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ35</accession>
    <name>A0ABR1VJ35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664705.1">
        <property type="nucleotide sequence ID" value="XM_066815415.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048475"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037869">
        <property type="entry name" value="Spp1/CFP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174:SF1">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="121"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8070897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="444" mass="48984" checksum="8D1B0BF9DE4FBFF7" modified="2025-10-08" version="1">MAGPDSLESEGDVQMGEADPGAGGGSLGHDDGEAPILKSVEQPTNFSHSNSGFEVKPDPEDDVNPPSSSPTSTRMANKSGPKKKGTAAAKKAKAAKKAAAAASGTVHEEEDESSDDEIDNGPYCICRGPDDHRWMISCDACEEWYHGECIDLDKELGEKLIERFVCPRCTDGKLHYTKYKKTCSLDGCTDPARLYGKKDRSVFCSNEHCDAWWASMIRTLPRKEASIEAAEMLTQEDFMGLLASTAHQGGWKLGEKPFGNIEGFWANGLPTRPDVLSDEELTFLQTSAAERLALGNEIVQYKKMMQLIDWANQRRQAAIEQGRFTKDSCGYDYRLDVVSVRHAFVAWVETPEGQATFTAGKLDTPIAPDGEGDPATRNMCEKKRCKAHNGWYKLLVSAVRNQIKETATAAADKLEAEDSLRQEAESRYERRQVENNWVEVIGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJT7</accession>
    <name>A0ABR1VJT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Appr-1-p processing enzyme family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665312.1">
        <property type="nucleotide sequence ID" value="XM_066816022.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049082"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="29107" checksum="1065B26922596AE3" modified="2025-10-08" version="1">MSASSGSTTNSNPHIPHIQLLCMQDKYIAAFNEAHQHHQLPDTISIAVHDYALSQLPAAVKFDTIVSPANSYGVMDGAFDDAISRALSPIDDYGALTRAVQAQLYRQWRGFAPPGTCTLIQIPWDDGKFAARNTRSRNVWGVKRVALCPTMRLPSDAEWNREVVYECVWGLLCAVDNHNRAVREGKAAGNGGDEDEIRSVLMTPLATGVGRVSPERWAAQAVLAMKHFEDASRNPETWSRLGWKELGDYSLEVEATWKQEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKQ9</accession>
    <name>A0ABR1VKQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011023</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664628.1">
        <property type="nucleotide sequence ID" value="XM_066815338.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048398"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07599">
        <property type="entry name" value="BAR_Rvs167p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF2">
        <property type="entry name" value="SH3 DOMAIN SIGNALLING PROTEIN (AFU_ORTHOLOGUE AFUA_5G07670)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="6">
        <location>
            <begin position="7"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="432"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="278"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="348"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8070820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="493" mass="53712" checksum="781AE9A1B25D1A67" modified="2025-10-08" version="1">MQSMQRSFGKLLNKSPGDNAKVSVLLNDYDDIDKVLAKLNDHTKSWRDSWINLTNTQLGIVTEYESLYDPIVGSDRTNVKATAPTPELQLNRTFKLKEAYGELKVDLMEEIASIDERVIRPTIDARDCIAPLRKTIKKRENRRLDYEKAQDKATKIHRKPGKSPKEEAALAKAEEEVARAAEEFQIADSHLRETLPPLVNATFSLVPPLLAAIVLINNRLLGLYYTALHGYCEDHDFPSPPPPMEDVIACWSADYSPVKRDFESISCIAHGKAAKLPMHITPEEVPSPNEGRKSSMPSFRRSPSGLIGSSKSDAGDEPGPGPMPPRPNRIPSNTSLSSQPTPGPRPPNTNLGVPTEFTTASGYGSGRRSPGASPNSLKPRSDYFGGSQSNRPGTASTVASNVSSISLGGGAPIVKKKPPPPPPKPKRITSNQPEVFVVALYSFAGQGAGDLSFEEGDRIKVVKKTGTDQDWWVGELGGVKGSFPQITANRFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VL07</accession>
    <name>A0ABR1VL07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rho1 guanine nucleotide exchange factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011113</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664718.1">
        <property type="nucleotide sequence ID" value="XM_066815428.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048488"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04435">
        <property type="entry name" value="DEP_fRom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041675">
        <property type="entry name" value="PH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052233">
        <property type="entry name" value="Rho-type_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572:SF2">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15405">
        <property type="entry name" value="PH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="4">
        <location>
            <begin position="541"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="5">
        <location>
            <begin position="906"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="325"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1235" mass="139398" checksum="05581778A83782CE" modified="2025-10-08" version="1">MADYQYDQRRYGPGGNNGQRDAAFSNIFGAAPPPGRSQTMTSSSPDMPPPRMMPQDGRTHTMGSGMPPPNMHQRQPPPRQQRAYEDPAVSGRTRTMDTSMANGYYQSQRNPSGGYPPPQAPQQYGRPMPAPDRRPYPGPPQQGGQPRFDPRGLPPGPAAGYPPRGPPQKYGPGAPPGSSPAMRDDPYRSQSLASMPRQNMYQPPPAAYNQPPANSFRGSPGPAPASRTTAQGRVVPERHDDRSMSLTGYHPQERDAHQTMSGRIIPNRSRAPSNEAPSMNGYANFNGYPPAPGAATRTMSMASSTAPPADHNRTMSMASSIAPSIAPSELGGSNPRKDITHRPSISGRSIEGERPPTAKIRSPLVYPALLSKVGECFRQKIITGERTKNGLAYKNAFSGSEAVDVLSYIIRTTDRNLALLLGRSLDAQKYFHDVTYEHRLRDSTSEMYQFRETLMDEPEEKPLVNGVFVLLSECYSPTCTRDQLCYSIACPRRLEQVSRLNLKIQPGLKKEDDAINDNDDVDQTDEQKLWINTVPKEIVDSRQEVISEICYTERDFVKDLEYLRDFWILPLRSKGSPIPAQRRDKVVRNIFGNIIDHPAIHTVSSRFAKSLTERQQKHPVVKNLGDIFLEFVPQFEPFILYGSKQMEGKFEFEQEKSNNPFFAKFVDEIERRKESRKLELNGYLTKPTTRLARYPLLLENVLKYSEEGSSDREDIPKVLVTIRDLLTRVNAESGKAENRFNLRRLHDQLRFRPADRVDLRLTEDGRELVFKTQFKKSPNDQAEITAFLFDHAVLLVRIKQAGKGEEIKAYRRPIPLELLSIREMDEVIPQQGMKRTSSSIIPLRAGNTDNKKVEGWPITFRHLGKNFYEQVLKKWLEYIDNAQQRLRARADFFNVGVVSAEFFSAANHINTATPFDGGRKLIYGTDNGIYVSDRKNKDATPKRVIEAQSVTQIDVLEEYNLLLVLSNKTLVSYSISALDPNEPALSKRPKKIQSHCTFFKAGICLGRHLVCCVKSTALSTTIKVYEPNDAMSKGKKQKGFGKMFNAGQDELKAFKEFYIPTESSSVHFLKSKLCVACSRGFEVVSLETLETQSLLDQADTSLDFVARKEGVKPVHIERLNGEFLLNYTDFSFFVNRNGWRARPEWRIDWEGTPQAFALSYPWILAFEPNFIEIRNIESGAVHIVPHKNIRMLHSSTHEILFAYEDEQGHDIVAAIDFWKNNRKSEMPTLDKGAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VMJ8</accession>
    <name>A0ABR1VMJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HyuE racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665243.1">
        <property type="nucleotide sequence ID" value="XM_066815953.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049013"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052186">
        <property type="entry name" value="Hydantoin_racemase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053714">
        <property type="entry name" value="Iso_Racemase_Enz_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047:SF5">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="108" mass="11709" checksum="9DFE17D2642DB274" modified="2025-10-08" version="1">MSIQVIRNEHARILVLNPNSSQSMTDGLNPVIKSVGLSPTTQVDTYTAPAASPASINNGEDIDASFKTVWDTFLKDGSEPPAYDGILVACFSVHPLVSSIERHFPKWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VMS0</accession>
    <name>A0ABR1VMS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665017.1">
        <property type="nucleotide sequence ID" value="XM_066815727.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048787"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF2">
        <property type="entry name" value="DUF3602 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="151" mass="15768" checksum="3659C1B576E1D931" modified="2025-10-08" version="1">MPRFTVNEPHPTVEKDSYTHSGRGGAGNFFRAPETTPSTGISTEPITTAPRPSMGRFYSGRGGAGNAHASAQRPVMSFEESYKLQSLIEEKATGYVGRGGAGNAVVKGVPASSSGGQRKGSDASSVASSRSSGSIRSNLMERISSTLRRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTA1</accession>
    <name>A0ABR1VTA1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665445.1">
        <property type="nucleotide sequence ID" value="XM_066813483.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046543"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="100" mass="11134" checksum="BEEA67807E79C232" modified="2025-10-08" version="1">MVRGDMIVIEVGKLLGRAFESTEGMAQHEENGVLSPDIPGVRIELAEEYAEPRQKDSKIENGIGGHMLSDVFWLVRRKPIIAKQEPEQASAAVTLLRNHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU74</accession>
    <name>A0ABR1VU74_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665743.1">
        <property type="nucleotide sequence ID" value="XM_066813781.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046841"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045948778" evidence="2">
        <location>
            <begin position="23"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="173" mass="17600" checksum="0D403580086FDF74" modified="2025-10-08" version="1">MAFTPVTLFYLLLSLLSLQVAAESVDVVDGLAARQAPGGGGGAPAGGQAGGLVPTVVSCAEYSRIANLTIIGKNSTYRAAFLRSGPFGTDQMSGMVDQAAVLLPPLTLDKTLNAQCGNSTAIALAGAEANFTQGIVADFTIAEAPGIGVDGFSTLIIVTVLTVFMGIVWMTME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUB7</accession>
    <name>A0ABR1VUB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665786.1">
        <property type="nucleotide sequence ID" value="XM_066813824.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046884"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039966">
        <property type="entry name" value="C553.12c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40467">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40467:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="490"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="534"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="609" mass="69550" checksum="B729386A9195601A" modified="2025-10-08" version="1">MGNGCNETSQAARQHASDASPLLGRFRAVPRSQQRRHSASALGFLSNGGGRGSVHVGYGALIASELDRAPDDDIEDYEDNDGAGYGHRAYRWMRRNVEDLFVAPRQTAVKRVVERWWTRWGVLVILPAALAVAWCAIPFPQYPLRPGDPDRNPDYDDHRAPGHGAARVQVNFWFFLIVYYGFYNLTALMWITKVFNLYSLNWWPSNLGFPLTITLIAVLGLAAPIPVYLVPELKFLTIHNTAWISWTFVIMAMPVAIAFCILMLHERHLGLRNSLSETQRIFTSSWWTSEGDSTADRDRHRRRMGLNDYNVDPDNVLHARPSQRGRVSAMMRRRWLPASFVRFVWFCLALLVGLLAYLIGEAYAEIYLRTLPHNNLETVVYVYSWVITVHLLDALTGWILGVSEGERVGSYPLSWIFKLYFILTYQTYVRALYARLRSPSQFILLQALSSTSLIVFVPLTMSMTYHRIMTFLGLTSQSYAAYQKLCIRNVFIRFIAENVSMLAFLGSILVLHFGSNKDVYPYFAFDDPEDIEDGYNFGFTFYASTITWACELVAGFLLRALIRWCFGVNASVEGKLDLAVWPELLPTSIAVMLHVLQNMLFSIIRLHFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUM1</accession>
    <name>A0ABR1VUM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 17</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED17</name>
        <name evidence="10" type="ORF">PG997_009613</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665890.1">
        <property type="nucleotide sequence ID" value="XM_066813928.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046988"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019313">
        <property type="entry name" value="Mediator_Med17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114:SF7">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10156">
        <property type="entry name" value="Med17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8074950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="614" mass="67721" checksum="009A8AF8E465DB99" modified="2025-10-08" version="1">MEHQSPFSLRPWPRGDKKPKNIEEFVQRVSAERNGFRNVKEADLVEEIKAHAAGAANPDNSQGSPEGDSDSDAEAENDKKEKTAIEARDDFLRNLEAAHQSAMLNLDLVSLLLSKETPNQAGTTLSPTLRELVGIGTLGSSKVHQSNITPAREADDLAVGTGWRVMGTNKMVSSVLEAAERLEKEITLETKYWADVLAVSESGWAVSSIAGKGLGVRFGFAEAAPMYRDSSIARLIRSEDGNARLDHGQAGKGSQRVRATIEVDGKIAGRSRLPGSLPDNSRLEDRVLEARNTIFAQELWYEISRESRTLLSLGVQSDGSEVSYNVNPATKVILCLEDLAEPELPDETNFYDLMAELTIQGLSIFLMAAHRQNYSKRVQPKHGRNNPPYNLLRPLISRYRFTLDYDKLIGFTGSLIDSLHAAGFDSADFTKTQPSLSLQPPTRADTDHHVMTQAEMLMLNTINFQQFSADITITPEARIGLRAKAFLSLDATQFKIALPGPQNPLANLYTSSDTYPNVGEAIHYVRQATIRAVVDRLLELTSEKLAKEDIGWSDAMDGVALVDTLDRELTIGTDGTQLVAKTKNQRRIWSVGTSSQANLEEFVLSYFKSNEDTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUN0</accession>
    <name>A0ABR1VUN0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PARP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009629</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665906.1">
        <property type="nucleotide sequence ID" value="XM_066813944.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047004"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001510">
        <property type="entry name" value="Znf_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00645">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01336">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PARP-type" evidence="7">
        <location>
            <begin position="6"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="104"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="236"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8074966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="322" mass="35373" checksum="025143784696E248" modified="2025-10-08" version="1">MSYRIEISPNNRAGCQDTLCKKEGNKIMKGDIRWGVWVDIPDGHASWKWNHWGCVSGLKVTNLQESISDGGDNYKWDMIDGWEDLDDHPEVQEKIKKAVTQGHIPAEDFNGDPEFNVPKQKAIRGRAKKAKKGDEDGEDEAEKPTPKAKRGRKKADADEDDEEAQPAKKKAKKATPKKAAAAEEKPAPKAKGKTAGRGKKVKEEVEEEEQVDEPEPEPAPKPVKKGRGKKVKEEVKDEEDDEVDEPEPAPEPAKKGRGRKAAKAPTPVEDEDEVEAEEVPKKAKAKGGRKAKASTAGAADAAPVTARRGRSRKSKAADEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVQ4</accession>
    <name>A0ABR1VVQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trichothecene 3-O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666266.1">
        <property type="nucleotide sequence ID" value="XM_066814304.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047364"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051283">
        <property type="entry name" value="Sec_Metabolite_Acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054710">
        <property type="entry name" value="Tri101-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896:SF64">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22664">
        <property type="entry name" value="TRI-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Trichothecene 3-O-acetyltransferase-like N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="359" mass="39302" checksum="C52AB68E510F64C4" modified="2025-10-08" version="1">MPSLEDFRAAGCPMNCLDEDLVAPRRTSSGRPGETTAEVFQLQASIVNGGLILTFLGQHQCMDGVGQGQVMHLLSKACRGEAFTEDELRSGNRDPADKIPLLDDTAWVPGTEPRYNKVEPLPVGDVRQPMPTGVWCHFSFPNGSLLTLKQMATQSLPTATPYISTDDALSAFVWQSIMRVRLPRLQEDSPVLFARSVDIRHHVGISATYPGFAQCMTYHYKFSARQLVESPLGAIAADLRAAIATETSTLAYDARSLATLVDRTPDKSTVSLLGGGFDMTRDVMLNSWANQGAYHLDFGLGLGRPESVRRPRFDAFQGLVYLMPKRPDGEIGVAVCLSEEDMQRLKGDGGFMRFARLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX45</accession>
    <name>A0ABR1VX45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009564</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665841.1">
        <property type="nucleotide sequence ID" value="XM_066813879.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046939"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="5">
        <location>
            <begin position="149"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8074901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="497" mass="55847" checksum="B8DD4A374B9C69A8" modified="2025-10-08" version="1">MKKYPDDPTPFTVPLDMNDPDTTMLSTWGSRLLYESDTTDAVPEVDLWLRRIVARCLADNPGERPNHRQLVDECEDALRQMRAPLSDRYASAPSETDEAILEFLKQYLYMPSPEPGPALGDTFLPNPFSMPEAETEGDNLGDNDQAVLVYSSNRPNEKNEDRNSDDTFFVNGALFRIVGVYDGHGGPWTSEYLSRALPGAIQQSIQDAGAAASSIPNIMASSFEQVDRSIIESAETIFAPVLSSLRYNLPFTRQRNEIAKKAAVEEVLQTQSHLDTALRAKSGSTALVAYIDRTDIHVANVGDCRAVLARRDAHTRNLEAVPLSIDQDGHNSAEYTRVTREHPKDKKDIFAGSRLFGMMPLTRSFGDAFYKYRTTDIAQYVFGNAQLNKKGHLSYHETMSPYYPLLESPPYLTATPEVISHQRSHDDVFMVMASDGVWAIKDMTNEWVVDKTMEALSNASVDDPSRYVMEELKKWKPGDDVTIMNREIDWQAREPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYT8</accession>
    <name>A0ABR1VYT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666275.1">
        <property type="nucleotide sequence ID" value="XM_066814313.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047373"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="56627" checksum="4A90853F837C692D" modified="2025-10-08" version="1">MVTNDSTSIISLPSSPAQDNKLGDDIPSLDTTFEALSEAQESSVESDELSLSDLDDDLVNLEDPHFEDELFLVIRTVSAKLLAGFRLTGTSTEGFIGHSQGPGILTLGECSSGEGLSTDNTEGLEDESSTSASDPGNPKTFRSIRPKRERGNALERDREGGDEEDEDDGGNIRLPKKLRTAYCDTGRKFLACPFWKLNARRHRDCFKRKLDGIPRVKQHLRRNHYNGNHRCERCKTVFVDDGPYQDHLRQQCTFREAAVPEWISHQTRLALARKSKPQYSESQKWFEIWDLLFPGAPAPSLAYIDPNLSEDLSEFRLYAHDHGPRILQEELENVGVRFEVESSASRQDVVSAAIRRAQEQLLEEWLESYSLPPEASSDLPESVGASSADIPEVDAYVQPILNNAPIINSQGTPGITRSLDELPDVDVAATDDQQQGIVLLTVTDANHDDPSGRIEVFPRDNDRETGEELDMFIDYWPGVMGAFSEMEAEVYYDIQDVSSNQQVYEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZ39</accession>
    <name>A0ABR1VZ39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009786</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666063.1">
        <property type="nucleotide sequence ID" value="XM_066814101.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047161"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="56685" checksum="71F4639C57DE5F29" modified="2025-10-08" version="1">MHRYAKATLLLLVALVIYIIAKSKLNKRRNNAKAAALGCQSPPVVRSRNLLGNSVLRDSMRATKEDRGSAVRLPILDYEIICTRDPENCRVLFTSPDFDISDTRQASWMPLLGKGIFTSRGDIWKHSRALLRPQFSREMISDPNLEEEHLQNLYERLPANPSTGWTETVDLAPLLFKLTLDTSTDFIFGRSTYTLKKGGAITDKNGKEIDHHFDEAKVWIDKRGALAKFYWLLNSKEFKEHCDTIHHFADSIVAERLANKAEKKGGRFNLLNELAVATQDARELRNETLHVLIAGRDTTGCLLGWVFYFLARHPEVYQKLRKAVLEQFGENQADFRALNNFNYIQWVINESLRIATVIPMNERRAQRDTVLPTGGGPDGESKIFAPKGTQVIIPLYAMQHRKDIWGEDAEDFRPERWATHRPGWEWLPFGAGARKCLGQQFGRQEVSYIVSRFCQKYDRIENMEQGDGRIRLHHAIENRSGTGVQIRLREAKHST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZI7</accession>
    <name>A0ABR1VZI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666681.1">
        <property type="nucleotide sequence ID" value="XM_066814719.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047779"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053225">
        <property type="entry name" value="Acyl-CoA_N-acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958:SF6">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="44918" checksum="D969FF88030B20ED" modified="2025-10-08" version="1">MREVQVYAVQPNGEFVLESPVPGCTDEEGASPYSSVDVISFLTRRLPRSLPPAEGKDEEQGPAAVRPEDVWTMLVVDRASHPATEIWSFSSLEMYHGTAPHEKGPQRASVLPDTLKDQLPFSEEVLDAATAQLLGAIAHIPVTWRDTTGTKLPAERLANVRHTPGSPYCLFGNTHSTVAALLARADTGAGDLVLDPSVPYGKYVFPVPAAAKQDEGGEKEEAQLPEGLIWSTISPDDYTNVMAVNKIIRSPSTLAKLQNAAIREAAPRPDGKPGKAVAFAFAAGDGSVRTLHVDPAYRRRGLAKAVVARLLGMGLFEPPRDGPLAARPEVLEELLAENGEQAEATLAFAGIEESNTGSIRTFRALGGKWLWDVYWIYLDLDRARELAGGNLRSSAFYERHASIDIFVWLKQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7M4</accession>
    <name>A0ABR1W7M4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAUS augmin-like complex subunit 6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666882.1">
        <property type="nucleotide sequence ID" value="XM_066811540.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044600"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028163">
        <property type="entry name" value="HAUS_6_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14661">
        <property type="entry name" value="HAUS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAUS augmin-like complex subunit 6 N-terminal" evidence="2">
        <location>
            <begin position="47"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="748"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="548"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="773" mass="87416" checksum="77663725DDCA8988" modified="2025-10-08" version="1">MALPPPKPATTRPRRISLRASAKNPLTSAQPANNAQLPSTVSSRTLFLTNLRLLDLDQEEDWPDLTPATFSAKDAAGGQKKRIQAVEWALYQLFNLWDPEETLNKIRPFYPPLDGVQSINLRAAFLRCLEQAKKNGVLGRDAVIRKTMLDECKGERFEEVLAVFSSAVLKKLVAERALNAGHDYRPSISENIAIENWGYKGERTELNGLLIAHKASLRAFLRDKNAARERYRDFEQLLTRKEETIAKRSEQVNSLATDDPNDQPSEKTRYKVRQMLKTNWTGNDQWTENILYGENSSSKGGLLSTPFEKVWDGVQNGTLTDIEDQSTGLLDQLDQRVQVQRERLEKWDGFRKKLFGDKAAEPRKAPGPDSKGIDLGFTAHLKLSADTMSPQDLNNVHLPPPPPQYAELLDNMKAELDSDLARIPSFASLVKNRSTANAHRAQEPPEPLSDLDEWENELEREAKLSRPPANRHGSRLRSPKKRPVIRTHTMNIRPPIESSDDEEEEEDESEGMETPRQDRHDSMPISRSSVTPDQEEYEEEQQGSIKMLRYSPPLSPPRSQSPELLGTEPRSKKEAAPEELTAPGRAPSPTQLMANQILASMSNASPSPLKKARHTLSLTERTRMSMSRTPSFEPDWDEPDTTQLLSPTPRPRVNIQALSGDPADASASDDPEDLVARTRRSMQGYEAARQKAQLERRRSERKSRMETPRKANTFPIMEEEGCDEADQTTIIEELLEQGVDDMELVFRSRPKMRMSPAPSPGRRWDSELYDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W991</accession>
    <name>A0ABR1W991_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667523.1">
        <property type="nucleotide sequence ID" value="XM_066812181.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045241"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="315" mass="35591" checksum="FE2E7FC376D7F045" modified="2025-10-08" version="1">MLVLYECSQKRPVTSSGLPRELSYWAGPLTSVRLYDDHVSQWCQSGVDTRQVWELFVDPSGSKGITLVSAKQRRYANSPAYIILYRAMNLEEVHSQYLMLREKHGGAYNIMRQWVQNHGRLDGDDGSVAQLIECVLYWSQSHAWDDLDGPTRPNVPPTLISTHLNAWIIANIVRQRWLGIESILASKQHSSSSEPGMPARRNPIFGDPSHLYADRSIGTIIALWEDLTDNLICRLNAIADIAGLAPSLFEAELPAAESASQRGFLDESFRQVTCRLEEFYRPAKSCHNRTDSSRERATKDKAFTIGHPFTVECQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9W6</accession>
    <name>A0ABR1W9W6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3 10">5.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_008076</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="3 10"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667733.1">
        <property type="nucleotide sequence ID" value="XM_066812391.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045451"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001211">
        <property type="entry name" value="PRK00179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469:SF1">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8080258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="552" mass="60744" checksum="CE0CDBA1AABF2618" modified="2025-10-08" version="1">MAPANSLKAWAELDAHFRSVGSDLNMKAAFDKDPKRFETLSKTFKNSPSNTDILFDFSKNIITSETIDLLVKLAQEAGVEKKRDAMFAGEKINFTEGRAVYHTALRNVGGWDMKVEGADVMNNKGGVNEVLNHMKEFSEQVRSGEWKGFTGKKLTNIVNIGIGGSDLGPVMVTEALKHYGADDMTLHFVSNIDGTHMAEALKASDPETTLFLVASKTFTTAETCTNANTAKTWFLEKTGNKGDIAKHFVALSTNESEVTKFGIDAKNMFGFESWVGGRYSVWSAIGLSVALYIGYDNFHKFLAGAHEMDKHFRETPLKDNIPVLGGLLSVWYSDFFACQTHLVAPFDQYLHRFPAYLQQLSMESNGKTITSDGSIAKYTTGPILFGEPCTNAQHSFFQLVHQGTKLIPTDFILAAKSHNPITDNLHQKMLASNYFAQAEALMIGKTAQELKDEHTPKDLVPHKVFPGNRPTTSILVGGHIGPAELGALIAYYEHLTFTEGAIWDINSFDQWGVELGKVLAKKILTELDQDGEGKHDSSTGGLIGAFKKYASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAC1</accession>
    <name>A0ABR1WAC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-amino acid oxidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008277</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667934.1">
        <property type="nucleotide sequence ID" value="XM_066812592.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045652"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006181">
        <property type="entry name" value="D-amino_acid_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF16">
        <property type="entry name" value="D-AMINO ACID OXIDASE (AFU_ORTHOLOGUE AFUA_5G11290)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00677">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="192"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="316" mass="34918" checksum="4AD9F9B255513EEC" modified="2025-10-08" version="1">MKSQPETIHELKTNTISQSAGVSGLTSAYLLSKESANTITVVAKHMPGDYDIEYASPWAGANVLPMATKPSSRWERQTWPELKRLAEEVPEAGIHKMKSRVYRREKDLEKLRGGEYAFDGLFKEDPWYKTLFEDFRELSKDELPSGVASGAEFTSVCINTMLYLPWLVGKCRANGVVFKRGVLQHISEAAAGTILGGTYQKGQWESQADPNTALRIMKRAVEMVPELADGKGVQGLDVVRHGVGLRPYRNGGVRLEKEKIGGTWVVHNYGHAGWGYQGSYGCAERVVELADEALNQPKLASAPNELKLSPIAEPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBC8</accession>
    <name>A0ABR1WBC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668279.1">
        <property type="nucleotide sequence ID" value="XM_066812937.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045997"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="216" mass="23210" checksum="311D1FF14A13534C" modified="2025-10-08" version="1">MELHHPHETPGTPNGGLADSVHAPSNSNSSNSYPSREQAVVTPTPDEYDDEDAAFMMPRDVTNVPWHARNDSVPQSMRSFSTLDDSVASSPVHSALLADRHEPVIRDSWPSMPFGAGRARGISQLTESSAGGSAREEFDPFRYDVNASGKPAPPPPTSWAPPASTKPPSPPVSNRYDSRDAASTGEAVGALVEPQLCLGRQRPCEFPHVRQAAQHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBI5</accession>
    <name>A0ABR1WBI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mas3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668335.1">
        <property type="nucleotide sequence ID" value="XM_066812993.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046053"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF4">
        <property type="entry name" value="CAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045122515" evidence="2">
        <location>
            <begin position="22"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="257" mass="27316" checksum="01AAB06AB3FEDC08" modified="2025-10-08" version="1">MSSFKAIVALGLMTTAQLVAGHGAIIKAVGNAGGSGSNGPRRPDRHPRDGTRRNPFQQDSTRFKGDNKATVGETVGGGANDLEAGTKAIMAETGTMLPQVTAGGEVEMTLHQVNADGGGPYTCMMNSDGTAAKWTDIQVTQSPPGENSRNRDGAKTDFPSRPRSRPMRLAPAPSRGRTMSAWFAARTRRGLGPSVVSFPSRVLAGSSTPAAARRALAQAIKRDIQELKAMQKRAKTFSPEDLAGMYDEEDEDEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBJ9</accession>
    <name>A0ABR1WBJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008631</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668288.1">
        <property type="nucleotide sequence ID" value="XM_066812946.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046006"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF67">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04010)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="49"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="519" mass="57539" checksum="B19D27494DF0B702" modified="2025-10-08" version="1">MPPIIGNDVEKSHLDEVEQRDLSTGSVDVDEHHMTRKVLWKLDTRILPVLAVLFLCSFLDRTNVGNARLALVSHSLETSYRLEEDTHMSDHQYDQGLAVYYATYIASEIPSNLIMKRVSPKKWLPFLTFAWGLVAMCLGFVQNFAGFVAVRAILGLTEGGLLPGMILYLSGIYRREELALRIGLFYTAASLSGAFGGLLARGLAEIGSRGGLSSWRWIFVIEGLLTIVVAIAVYFILPNGLADAKFLSPEEREFAMRRVHGSGRGDSLHEREANERFSWSEVRRGIFSFLTWSTAIAYFGILSGLYSFGLFVRYPDPYRYTTQSPPNRLVIQLPTIIAALGYTANEAQLWSVIPYAAAAVVTVIVAFLSDRLRVRGIIMLFTLPIAIIGYAAIANTTNPRVKYGMTFLMATGLYSSVPPVLGWLSNNSAGHYKRATTSALQLAIANAGGFVTVFVYPKSQGPQYHEGHTIILGLLVAGWFFILASVLYCWKVNKDKAHGKYDKFIGSGDDRDPTFKLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCI2</accession>
    <name>A0ABR1WCI2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pantothenate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668607.1">
        <property type="nucleotide sequence ID" value="XM_066813265.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046325"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF51">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8081132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="505" mass="55862" checksum="1DD4C9776FF9DFDD" modified="2025-10-08" version="1">MSDPKDLAMAIKAGPTGIKPPSEELISSNPDSGVPSVEISTSDDERSRARQLLTPEEEKKLLRHIDWHLMPLCSIIFIFKNLDSDNVSNARIMNRGTERNIMTQLGMSSDAYALVTVFYYIPYIVGEAPSNLLIKRFSPSKWQSRILVSWGIVLGLHCLARNSAGLYTTRFFLGLFEAGQFPGVILQMCYWYRPDEMSLRLLYFYICGNLSGIFSGILAFAFDHLSGYGGLSGWQWLFLVESLATVVMGVIVWFTLPDFPDTASWLSEKERAFIQARLPPNFSEIVSSLKDVRLWLFTLIWALFTVGTSGVRFYQPTVIANLGFTDLATAQILNIPITALGLLLIAATGLHTDTARLPRPLYPLSFLAVILLSYAVLVAYPSNAAVYAATLLGNAATAAWYPTMWPWRVQTTQRATGSAFAIGFVNSYGQIGGAVGPQLFREDYAPRYRVAFGIAMGLVGACVGVTLGTWHLTRGTERETRRVKREKLAAARRGEGFVGEVGDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM46</accession>
    <name>A0ABR1WM46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669095.1">
        <property type="nucleotide sequence ID" value="XM_066810172.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043232"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046312">
        <property type="entry name" value="DUF6454"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20055">
        <property type="entry name" value="DUF6454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="152" mass="16595" checksum="9961158EACB8C5FC" modified="2025-10-08" version="1">MPEEYHLGGLEYDGRFLWATASQYRPTTTATLVQLDLSVPSSSSHSTTTLLGPVEPLWHIRDHQGGVIRDVSTQTLLTLNWGSRAASLWDLRDLRDPAAAPFPCSAQPHTSGVAGLGRQCDHRGTGHRRRAVHGAAGRGTEYLDGRARRADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM66</accession>
    <name>A0ABR1WM66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Survival protein SurE-like phosphatase/nucleotidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669122.1">
        <property type="nucleotide sequence ID" value="XM_066810199.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043259"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="entry name" value="Survival protein SurE-like phosphatase/nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027746">
        <property type="entry name" value="TTL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551:SF1">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SurE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival protein SurE-like phosphatase/nucleotidase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="830" mass="92039" checksum="F354118B6C481049" modified="2025-10-08" version="1">MHILVTNDDGPPSPTSSPYVHSFVRALQRAGHTVSVCLPPYATILDRQGPYGGRDSEALLLPRSIPPPPSDSAAAKPQGTTHSRPSKSRDIEEWILVDGTPASCAQIGLHYFFEDRGPVDLVVSGPNYGRNATAVFALSSGTLGGALEAAVCRKKAIAVSYAFFSRNHDPEIIEGASAHSVRVIESLYRQWPSDTSVDLYSVNVPLVEGVGKNKTLFTEMLQNYWSQGSSCFTEVEGSVGAEDEEERRIREGESHEGVAPQEISKETENGNGYAHRHFKWSPRFTDVYNSVEESAPGNDGWAVKEGLTSITPMKANFYHAAPHLHGTELQLEQTQPQNDTKSMTQEHSLAHRPKSHFYALVAYEDPYVQPLILSALSKLFSADSYTLLSLPESHDPSSSSEISIASLLPLSAGGGSPSDNDTRILQITPYELVDWSYVSDDHKGNVMVNSYMLRKALIRKHYLGTTIEHWVAKHPESVLNSHYRRGDAFEVDYADFLDDALVEAFDLRASLDKNEEIEDAKDREWWILKPGMSDRGQGIRLFSTMEELQGIFDGWEDEDEEDEDEDENGDATAGRKEDDDEDDDKDDGITASHLRHFVAQPYIHQPLLLPAYDNRKFHIRTYVLCVGSLDVYVYREMLALFAGKPYVAPWETSAGDDASEIDLEAHLTNTCLQRTVKDGSVRRFWDIDIPITAAASGEPSKQAIFDQICAVTGDLFQAAAQGGMTMHFQPLPNAFEVFGLDFLVDAAGTAWLLEVNSFPDFKQTGDELNGLVQGLWEGVMALAVRPRFGGQEVETPSAVQGAREQKDRESYAEVRDMVHVRNVDLGRRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM88</accession>
    <name>A0ABR1WM88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="14">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_005885</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="14"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669123.1">
        <property type="nucleotide sequence ID" value="XM_066810200.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043260"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 14" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="536"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="577"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1011"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1081"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1159"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1203"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1351"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="18">
        <location>
            <begin position="299"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="16">
        <location>
            <begin position="406"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="17">
        <location>
            <begin position="1038"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="262"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1294"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1371"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="49"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1391"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1415"/>
            <end position="1432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8084614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1432" mass="154988" checksum="456ACFC88859E31D" modified="2025-10-08" version="1">MADSSSNQDAATPRRPRAPTITIDTTAVGASQDDDPDPTAAAPRRHSPISPTDDTVSPTSIANPVSHSWTSSDNRTNMPQRQPSGASATSDYQGSRSFDSDNSRPQSPHNVSSPVTSRGNDRVQNFLAVPNNYRSRQNSVDSEDGIRSIASASSIGETVAATASWQPDKGEKSVGLEVDTNNDEIMKATDALKPDAGNEADFEVQNNPFAYSPGQLTKMFNPKSLAAFYALGGLSGMEKGLRSNRETGLSVDEKHLDGAVSFQDVTKKDAKSTTEGAESPSPAAPVARANTANTAARESNDAFSDRKRVYGDNRIPEKKGKSFLQLVWITYNDKVLILLSIAAVVSLAIGLYQTFGTKHDAEHPGVEWVEGVAIIVAIVIVVLVGSLNDWQKERQFAKLNKKEAGSSLRSGQTVEVSVFDIMAGDVIHLEPGDLIPVDGILIQGYNVKCDESQATGESDIIKKRGGDEVFAAIENGENLKKADPFIQSGARVMEGAGTFLATSTGVHSSYGKTMMALDEDPEITPLQSKLNVIAEYIAKLGGAAGLLLFLVLFIKFLVALPHNPATPAEKGQNFLNIFIVVVTIIVVAVPEGLPLAVTLALAFATTRMLRENNLVRHLKACEVMGNATTICSDKTGTLTQNKMLVVSGTVGTSHRFGGDSENASAGPTAKELINSLGSDVKEILLKSISMNSTAFEGDVDGVKTFIGSKTETALLTFAKEHLGMGPVSEERSNSKVLQLIPFDSGRKCMGAVVQLPNGKARLYVKGASEILLAKCTEMLRDPSQDLARVPLSEESAENIRGLIDSYASRSLRTIGLVYRDFEKWPPRNSRRTDGEVNFEDTFQRMTFLGMVGIQDPLREGVADAVRSCQKAGVVVRMVTGDNKLTAQAIAKECGILQPEGLVMEGPEFRNLSRMQQESIIPRLQVLARSSPEDKRILVRRLKDLGETVAVTGDGTNDAPALKLADVGFSMGIAGTEVAKEASAIILMDDNFNSIVKALKWGRAVNDAVKRFLQFQLTVNITAVILTFVTAVSNETEASVLTAVQLLWVNLIMDTLAALALATDPPQDSVLDRKPEPRGSGIISTTMWKMIIGQAIYQLVITLLIYYGSPSILSYDDNIEKAQLNTLVFNTFVWMQIFNQWNNRRLDNKFNIFEGLFRNWFFIGINTLMCGAQVLIIFVGGDAFNIVRVVNDQGQKSPPQTGAQWGYAIFLGILSIPVGAIIRLIPDSLLASLVPEPFKRKSPRLPGLTVSDEERFNYYPAAFTEVRDELAWLKRIKGGRLNNLKFAMQHPREMLLNRSRSKSPVHSRSNSVSNKPFPPSTPVREDSVGSMAPTPTPDSRKRSRSMRSRSNSALGAPTVMAGIIAGSIAAGWSPVERNGDDTTAGQPPRPSPLSQQQQGGAAAPMFTEEPESMEGESSRPRATGGEHRWMSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMB6</accession>
    <name>A0ABR1WMB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669193.1">
        <property type="nucleotide sequence ID" value="XM_066810270.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043330"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="115" mass="12927" checksum="9E5493B938B43174" modified="2025-10-08" version="1">MVELKEELCLLGLPPQILDRSCWMLRESSEEIVVLEPAAYLDVVTGRPWETRDGDQLSRLGSSASIGFKSLMTFSPTAAQRNARRVRRHGTLMHKPYEIWATAWAGCLPSIAEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WML4</accession>
    <name>A0ABR1WML4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669289.1">
        <property type="nucleotide sequence ID" value="XM_066810366.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043426"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="175" mass="19006" checksum="6B839E26AED01244" modified="2025-10-08" version="1">MSSPALARDSGAEQGKEETLAGNDGANVATKSTRQHSQTLSILIFKGKPEDTPAARVTDLYVVANDENNTNSTFRLDGQAGRYRASELWNLAAPRLRPDYRSQIHVATLPTSSAVETTLHDTIKGVVVNNEDPSWGCQHWVGDVVTTLQELGMISEDEGDRAIDAMMNIILSAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMQ5</accession>
    <name>A0ABR1WMQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_006091</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669329.1">
        <property type="nucleotide sequence ID" value="XM_066810406.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043466"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="65"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8084820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="711" mass="78776" checksum="9263F80F776DD00B" modified="2025-10-08" version="1">MDQPSTPPLCDGALTDGRGNPYPPAKRKGHHVYKPIKEIEAEEVEAYREGGFHPVQLGDRLNHDFEVVAKLGHGGFGTVWLCQEGPEVEGQTAWKAVKIIAASESYADNPELQTIEELQSQGVTRAQWEAAGVMLPSRHFWLQGPNGTHLCLVFPVMGPNLRSQLEASGETVKGVLAQAGRSLQFLHAHGICHGDFRSDNILLHVNDVEKLSKKEMLTLLEEPRTEPVTLADGGEPPEEGGRAPAYLVERSDIGILGPKTQTATIDFGISYRAGDPPEFVGIPAQWAAPEAFFRTGNTGEASDVWSFICMIQEIRGRGEFFSNITRPHYVLDLEALLGPLPDSYRLAWKLELQRDGVFEDSDEEVEVAEDGTVTRVTKPVSATVEDLEDIRQDVMERSGYADYLQAMIGADRGSIQYQRDVDYVPTPTYVPWRVPEEEVFQLADLCRKVLRYDPDERISMEEVMQHEWFKGGFEEVEQKSEASPTLAIQDGTKGKTGNVPEVEKKGVTAVETGDRKATTEDEVRSKSRVKPSRIPIATKDLIAINKKAAILAAQQWYRDFGERRKRRYRPQIPAVPHHPSAGEQIFDTCVYFLSILFLISAAMFIVVLLLPIPLPPTITIPSPSSGVGHPLRFPNIVAIRQAWCGVHGCRGSGIRIAGAAAGPIPWFRTRGVSPHSVFYEGIITLPRNNMNESDKGVEKKRFKGLLVIPGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNS4</accession>
    <name>A0ABR1WNS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkaline-phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006452</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669690.1">
        <property type="nucleotide sequence ID" value="XM_066810767.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043827"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16150">
        <property type="entry name" value="sulfatase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45953">
        <property type="entry name" value="IDURONATE 2-SULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45953:SF1">
        <property type="entry name" value="IDURONATE 2-SULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046264824" evidence="3">
        <location>
            <begin position="18"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="4">
        <location>
            <begin position="46"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="508" mass="58432" checksum="AEBCA83056634BAD" modified="2025-10-08" version="1">MRLSVWCTSLLAVAGLCQPPNPKPDYSFENPYTRPAKPNGLAIEKPNMIMFMPDQLRYDAVGVFGNKFVKTPNIDAFAAEGTRFTNMFVQASVCSQSRTSMFTGQYNHVTGHRTLNNLLKPWEPNMFRSLKEDGYHNTTELGVNEYGFLTNQTLPKFTAAFDYDEAMVRGALHWLECPPKEPWVLFLPLLFPHCPFTAEEPFFSMYNRSELPLPARKEDKTGFEPRFHRQIRDQYGTDRATDEVWREVKATYYAMVSRVDWQFGRIVNKTKDLGLWDQTVTMFFTDHGEYLGDYGLIEKWPSGVSDSLVHEPLIIDGAGLPKGVVYEEMGEMVDLVPTVLQLGSIPETYAQYGVSLVDAIHTTTKGEVLPHKKYSFTEGGFLVSEEPLLEQSPFPYDIKASLQHNDTSSVGKAISIRSKEWTYVYRLYEADELYSRKGDDAQELHNLAERPEYQRVRATLREEVFKWLVETADTIPWYEDQRRPSVTLANPHEQYVMREEKCDDCPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPI8</accession>
    <name>A0ABR1WPI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Formin GTPase-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669461.1">
        <property type="nucleotide sequence ID" value="XM_066810538.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043598"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06371">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formin GTPase-binding" evidence="2">
        <location>
            <begin position="329"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="797"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="807" mass="89275" checksum="F27FEBB112F954EE" modified="2025-10-08" version="1">MAFLGNPQHPDRQHCQDQYQHENQPPPPPKHGGHQRSKSSVLRAFMSRRNHANDAPVVVPTAQSTSSLPYVIPQPQPASDMQLPNFSRRPPALGEIQNNRVDCAPGPRSPSKLLEQSYFASGRGSPVKAQGSSIAARSTRKDSASSSESMGQYAFNKKENESPTKPKKTKSATNLTSLLSRPKSLKNLHNLQSEEDVVRSRNDKENRSPPNSVTTPSQEGRPPIYAQFSSGALEQTGNGGVFGPGQTNSQNSSSSDVTNMKKPRPQSYHVQYTAKQFESKKSSDSSESNRQGYGSGKTSPSKTQRGLKMFTSGFGKAKPSSSSPPPDGSEFSLDPKDIDKHLEAMLDRRNIPRKPEKSEPNSPAKKKSDGTLGRHFRTKSSESVTYERPNSAGSGFGGGILSKIKSQQSQQGPVDFVSYLRKVQKPQLVEVGKLHKLRLLLRNETVSWTDEFIRQGGMEEIVSLLHRTMEVEWREEHEDALLHENLLCLKALCTTALALQYLHSKQSTLFPALLHLIFDPEKKGPSEFTTRGIITSVLFTYIQSAPAQDRIVRARTVLGHLRDPKPKDDEAPVDFVLEMRRERPYRVWCKEAIGVTKEVFWIFLHHLNVVYLPRDKERDAAAAAKIAGDSMLYMQTHFPQERPPVPAAPYVGGVEWDATNYLASHLDLLNAIVACTPTTKERNELRNQFRISGWERCMGGSMRLCKEKFYPGVHDALRTWVAAASDDGWDVKDVRAGPPAESKSPAKRPASGKDNQNKGIKAQPPPKIEMPKLDFAFDAHVSPLGTPGGGFNKPAGANSSSTVNWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ82</accession>
    <name>A0ABR1WQ82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-O-diacetyl muramidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005862</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669100.1">
        <property type="nucleotide sequence ID" value="XM_066810177.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043237"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06412">
        <property type="entry name" value="GH25_CH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002053">
        <property type="entry name" value="Glyco_hydro_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018077">
        <property type="entry name" value="Glyco_hydro_fam25_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34135">
        <property type="entry name" value="LYSOZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34135:SF2">
        <property type="entry name" value="LYSOZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01183">
        <property type="entry name" value="Glyco_hydro_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00641">
        <property type="entry name" value="Glyco_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51904">
        <property type="entry name" value="GLYCOSYL_HYDROL_F25_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047167947" evidence="4">
        <location>
            <begin position="20"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="28763" checksum="89AC6585A45E7199" modified="2025-10-08" version="1">MLYRTALLTLTALMGTAQAEVQGFDISHYQPNVNFQSTYSAGARFVIIKVQPNPVPLLSPFPPRRTYTLKPLSYRHIHADTSIAHNKATEGTTYTDPKFSEHWTGATSAGLIRGAYHFARPNSGSGSAQATFFLAHGGGWTKDGRTLPGMLDLEAGSSQCYGLSASAMVAWIRDFSNTYHDRTGRYPMIYTNPSWWMACTNSTQEFAKTNPLVLARYASSIGTIPGGWPYQTIWQYTDKYAYGGDGDKFNGDEAGLKKLASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS12</accession>
    <name>A0ABR1WS12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006609</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669847.1">
        <property type="nucleotide sequence ID" value="XM_066810924.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043984"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="4">
        <location>
            <begin position="6"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="371" mass="39337" checksum="C5C3293420A4B5E3" modified="2025-10-08" version="1">MSKGTVFITGATGFLGSIFLLEALKKGYSAHVVVRSQSKGEIVKDFVASHGFSNEPVEGKPHCTYFTVPDLTLPGVLDEAVRGTDCVLHCASPLPFAEIPADRQQAEMIDPAIACTLNLLESVRTAGGATVKRVVVLASLIAFANAEVMGPTWVPAEGQEVHPNEDTLNDYISPPVPQPAPRVLRGQDGGAAQQPRLDEQQAGRGDPLGFDLVNLAPAYVVGRHPLAHTTADLMGTSNSMLLAPLVGRTSDPQGPLCVGGAVHVDDLTEICLESLDPAGKVKTPASGPDRGVANFCISVDVVWNDAKSLVAAKWPAHVESGLLPNQGDFPTKPRISFASRKTEEAFGIKLKGLEEMVEAIVPQYVELLQKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX84</accession>
    <name>A0ABR1WX84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002736</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670669.1">
        <property type="nucleotide sequence ID" value="XM_066807051.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040111"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="65"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8087775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="467" mass="51237" checksum="DCB9AFAE36C98358" modified="2025-10-08" version="1">MAAMSLRRKSCDACYHGRRKCDRDFPVCGTCRRTKKTCHFAYSPITAVISEPGYSVIASDVDNGGGTRPLTNSASAATTLTEPTRDPTDTGPPELADSGMLPDLVGGGQSASPFPGNQWPDDHNATASGVCGSNSFVADWAHCPVPASSSPHAPTVTIPPLSIPNYLGSLGQLQRVEGSSESWQWVINELKRCPRDLATRGESLFMHGELYRDAMPRPIRAVLGVSAIFALLNDDNRQVLFRVVDAEVSELLMTAPTTLDTSADADGRNGSQNRYISNELTLTEELARLQALTLYQMMRMFGGGLEQRIIVEQQHDLLTTWAQHLLKRSQNDLVANKANDAGGRHHHRMASDSDWHDWLVAESIRRTVLAVYMFYSMYSLAVHGFCADFPTLAKLPVSASPESWQSKTTHLTRRPSIGGQPDQTLAYDAYTQRWAASTPRRMDPFEKFLIVPCKGLEGIAAYGCSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX99</accession>
    <name>A0ABR1WX99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002746</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670679.1">
        <property type="nucleotide sequence ID" value="XM_066807061.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040121"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF13">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047246786" evidence="5">
        <location>
            <begin position="18"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="54"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="497" mass="54335" checksum="D3AC73AA6C662FF0" modified="2025-10-08" version="1">MASKVLLGLLATGLALAANTCDVVQDTTSIQMNKRFSIDYTNEQQEYWSAACTNQLKPSCILFPKSPSEVQAVVSILRDNNETFAVKSGGHNPNNYFASVDGGPLISTKHLNEVIFDKASETVRVGPGNRWEDVAKKLDGTGYSAVGGRIGNVGVGGYLLGGGLSFMSTEYGWAANSVVAYELVLANATMITVTAESHPDIHKALQGSGNAFGIVTAYTLKVYQQPAEVWGGHYTFSATTENNKKLLAAVRDFTEYYPDEKAGIILTAETTVGGLLDIWILFVYYNGPEPPAGIFSNFTDVGPLLKSVKKQSYADLLTGNNWAVLRGSVYTIGTEMTPLPSKEHGAEIMESYLDSWRNVSSGVLPVTGLIASVAFQPMPKRLAAKSQSKGGDMLDLDDGIDRIIFEYDYSYWIPSDQPKVDQAMQDTYNGLAGRVKEFQAQDKLPKDAYLPIFMNDGYFRQDYFGRLKPENAALARRVRDELDPQGLWATRTGGFKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXM9</accession>
    <name>A0ABR1WXM9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Purine and uridine phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670817.1">
        <property type="nucleotide sequence ID" value="XM_066807199.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040259"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049945">
        <property type="entry name" value="AAA_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ORC1/DEAH AAA+ ATPase" evidence="2">
        <location>
            <begin position="428"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="712"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="889" mass="98642" checksum="3A6625FAFFDCBB6E" modified="2025-10-08" version="1" fragment="single">NARTQSRRLHRGMDCPLEIEAQAALHMMDQQHRGRFPMGRGDDYVFHAGDIFGHNIIIATLPAGQEYGTGSAAALASQVKRFFPNLWFGLLVGVAAGLPSLSRTPPRDIRLGDVLVALPEGESAGLVAYELGKETTEDGFQPLRLGHVLATTETVIRSAIGSIKLRAPNDAPLFLDYYEAMKDRDHELGTFSDPGQEHDKLYMTGEDGMERVVDRPMRPAERRTRVWYGPIGSGEKLMKNARKRDELRDRYNLIGLEMEAAGTMNRIPVGVIRGVCDYGDVHKNKAWQPYAAAMAAAYAKAVLAQIPAKHIAVAEEPAPSQTSHPQSVFNGPITGRNVIAGMSTNGTANMNFSSTVLVANKPELKAMLDVDEAGSNLTCLIVTYPVQPDLPQACRYIPFPPNDDLVHRSDITDALTRLLPASAAYQNAALWGLGGSGKTQIALAYAYSRCRDPNCSVFWVHADTETSLAQDYKSIAARLGLPPELEGEDLLQAVRQQIEAGTNWVLVLDNADDLALFNVGRATQQSYTAQASTYGSTLHNAVPRGPHGTILWTSRDQQIAGSLVGARQAVHIVQMTAQEATTLLETVRNEETKEEEREDVQRLLDELGCLPLPISQAAAYIRRTSTSIAAYLSEIQKRKKRRKLLRRSEYDRHRRPEVSNSVLETWDISVDHLRGEQDDIPLHLIREAARLAEGTPVKLKRSGGDGTRSSESEEEEDGDSDSDSDGDDYILEAITRLREFSFLSIREPGAGASRAYEMHKLVQEAARYRLEKDKAAYFARAAFKVVDNLFPDSRRGTWLECEEYLVHAQHAGEWAALYKGEEEVAALLTRVSQYLYDRGRWREKEPVDKTTLSLRTKVLGEKHPDTIESMASLAVTYHNQGGMTRRRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXU2</accession>
    <name>A0ABR1WXU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670880.1">
        <property type="nucleotide sequence ID" value="XM_066807262.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040322"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF5">
        <property type="entry name" value="ISOFLAVONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="36053" checksum="880DCDFF1B9F3E35" modified="2025-10-08" version="1">MSARTATAMMRIAIAGGGGFANILVRELSESAHALIVLSTQEHPEFDEFDCQVAVVDYDNMDNLRFILQGVDLVISTICGTPQVNLIDAARRARVRCFVPSEFEGALSHRPGDTDPLDRGSSTALDYLRRWSTSRSHPMKFTVFSCGLFYERLAPGGLDAYSMGYSSNVQNEGDYLVNLRNGTAEIPEVNAQGRSVHITMTSVYDVARFVAAAIELGLDSWPREFKMSGASLSTKHLVEVCEEVRGDKVTFNKITRPYSELLSWLQHYEDHQDWTHWYHMQQLVQTANGRFHFSNPNLNEMVPVQPVGLRAWLQEIWGPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY68</accession>
    <name>A0ABR1WY68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_003029</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Vacuole membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670962.1">
        <property type="nucleotide sequence ID" value="XM_066807344.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040404"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <keyword evidence="11" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="96"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8088068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="165" mass="16670" checksum="BBF5D787A1BD2267" modified="2025-10-08" version="1">MSSVTFSEACPVYAPFFGAMGCTAAIVFTCLGAAYGTAKSGVGIAAMGVLRPDLIVKNIVPVIMAGIIGIYGLVVSVLISDGLKQELSLYTGFVQLGAGLAVGLSGMAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALLMNSKATLDSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYD5</accession>
    <name>A0ABR1WYD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tyrosinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003116</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671049.1">
        <property type="nucleotide sequence ID" value="XM_066807431.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040491"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045087369" evidence="3">
        <location>
            <begin position="23"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="109"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="368" mass="40432" checksum="9798B74C6C641B94" modified="2025-10-08" version="1">MQQQGLLVTLSLLLARISLVSSWTPAPTHGSDLLAEQSLANLKSVLADGTLKQELATQGVSQACGPDDWAVRREYLTLSDEEKLEYTRAIKCLMAKPATVDPEKVPGARSRYDDFVAAHINNTQFIHNSGYFLHWHRAFIWSFEQALRNECGLTFWTTGYLPYWNHGKGAQDLINSPYLDGSPTSQGGNGVYAKHGCATGLPSGLLCIEPGVGGGCVETGPYAGIMMNISATAPQFELVTAGPKFSYQPRCIRHDISNALGQKWAGDERAVDLLTNPAGQAGIAGIQEGIENTGTDTEGFYGLHQYGHFAVSGDPSGDFYNSPNEPIFWLHHGQVDRLWWIWQNQKPVERALQFAGTRTMYNEPRART</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYP0</accession>
    <name>A0ABR1WYP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonuclease H</fullName>
            <ecNumber evidence="3">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003241</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671174.1">
        <property type="nucleotide sequence ID" value="XM_066807556.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040616"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="9">
        <location>
            <begin position="100"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8088280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="267" mass="29942" checksum="9BBAF27615306813" modified="2025-10-08" version="1">MSGPRLSSLLKRVREYDEDPRPSKQTRRDQGYGEDTIEPHKGGQPHSTRDTYPRAGDYAMFKREMPTDPLELDMRGHLGFRHVRCPRGVSKCQCGLHAYHLDSLVIAIDGACPGNGSHKATRSGGGIYFGDGMGTDSTRSDYQQNFAFSVPDHADLPHTSQRAELYAAAGALLKARHYVEKGGQYPCGDKCATPCTVKHIVLKTDSAYLVNGITNHINKWETNGWQTAAGTDVKNRDLWVWVSTFGWYPESTTRRRTGWLPRVWCRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYW0</accession>
    <name>A0ABR1WYW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671226.1">
        <property type="nucleotide sequence ID" value="XM_066807608.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040668"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="21845" checksum="511886D18E51F53C" modified="2025-10-08" version="1">MLLPLPPSERTEVDKASMPDAPAVLPTAWKDSYTRRSLRPATIPAESQAVPVPFDNDVWNASRRSHSQSSSGQYDQQQQPLYQAYHPRFRTVDYQQRPSHQQQKQEQALPWPISPPRTLQIRPEFSRTLEPTMAPAVLDSVTDLATQRLSLSKDVLTGEGGKIPPAVAMVVVMNPSGEGRALQTHHGNTLDGYNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ59</accession>
    <name>A0ABR1WZ59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003408</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671341.1">
        <property type="nucleotide sequence ID" value="XM_066807723.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040783"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="47"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="191" mass="20675" checksum="FA955E506FFDE196" modified="2025-10-08" version="1">MDSTISAREANMSAKNLPRGEAPSNEELREHRSEKYSAFTDLERWVIVAIVCFASLCSNLSAFIFLPALKLLAETFSVSVDQINLVLTVYMAVATVAPTLAGDAADVIGRRPTYLVTLGLFLVADVFLALADSYEQLLGLRVLQALGQSGIIVVGYGVVTDITTPANRGSFMSAVSFAQSIPQRRRRTLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZS2</accession>
    <name>A0ABR1WZS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671572.1">
        <property type="nucleotide sequence ID" value="XM_066807954.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041014"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="142" mass="16222" checksum="250578A421024F9E" modified="2025-10-08" version="1">MPQPRKFTPPHPHLFTCTFCWHLSRGPPHVLGRAARLTCEACYNAIIDLAICWVCGEVVCRGDDRRVTQGTRVEELFLDDDFGVEEEGEEGWDVWDVEHFRAKEILEIPLCANCVVEVELDSLDRQTVVQKVLRRTDKIDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X006</accession>
    <name>A0ABR1X006_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003725</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671658.1">
        <property type="nucleotide sequence ID" value="XM_066808040.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041100"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF14">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="184"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="453" mass="50381" checksum="8311EADC4DEC798A" modified="2025-10-08" version="1">MAEFTGEQPSRSRARPFLSFETLFRSSTGVAASNLSRSDTPNPAVNGTLGDFHRILLRQGLQLNSIDTQKPFNRYLDMYMQCFPFVERSQLMEEFATVSQADLGNSDALLTDSPGKVVRIYAAVATGILLTPEYRHMETFATTLALTAHQHIPRVDESSGELETVQCLIAIALFSLFTSFGGSTWHLLGLALSRCVSAGMHHIRVSDAQSDDEEKRGCSRAFWCLYVFDTLISASLDRPYFVQDEDITTLRNAEKGALFHFINLRHFRETMPKSSTGFDDGSWLLNNLCSRFCCRALLEILSHLSPSQSTAETAMVVGYANEQLTGFLNLLDQNSTTQSCAFMGCDGLLVFRIGAELLCNPLFGTVRGGSNSATQVVSQTCLRLLVAISERFSSIRCLREILDRLVVFLATESRQNHADWLSLARRIESSDIPIPRRVQDLIYSIHINTPVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X093</accession>
    <name>A0ABR1X093_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">6-phosphogluconolactonase</fullName>
            <shortName evidence="2">6PGL</shortName>
            <ecNumber evidence="2">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003777</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671710.1">
        <property type="nucleotide sequence ID" value="XM_066808092.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041152"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="6PGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054:SF0">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="261" mass="28423" checksum="2EC46748346C8C3E" modified="2025-10-08" version="1">MPGKQPSLFAFPGLDELAPALRSYVISCQNAGLTRHGAFKVGVSGGSLPKVLAKALLAPATSDEDKVQFDKWEIFFADERAVPLDHDDSNYCLLKKELLDKIPANLGQPTVHPIDTQHLNDTQELADQYEQLLVRSFASRDSVKLPIFDLLLLGSGPDGHTCSLFPGHPLLRETSAWVAPIEDSPKPPPKRITLTLPVVTHSVKVAFVATGGGKKEIMKEIFEQGNGLPCALVNEATGERCSWFVDNPAVEGVSYPRRGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0E7</accession>
    <name>A0ABR1X0E7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ADP-ribosylation factor (ARF)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671738.1">
        <property type="nucleotide sequence ID" value="XM_066808120.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041180"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="273" mass="29647" checksum="4C8CA762BCC82742" modified="2025-10-08" version="1">MGIVSSRLDDGAAIYLRDQNRLSISSLVISNPRRRSAVTVVPNAFPATRATATRAPGDTGSVEFVQDNEPSATPNFLLKLSNEDELVFNFTFIVRQEAGASPTNTNINGLTYVYASTAREVENLVTREFHADPNLHKNSNVELVGDFSTGGSSSVSFEWSWKWKPPRPIEDRGGGWRNTCSFVEYDPRAHKLVTLASFSFWVASKHLPGVAIELLPASPNEPTDAGFAPSHPSSPSPVFQLAVPPKIRVASAQSVDSRISEQDEPGSPPELAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0I4</accession>
    <name>A0ABR1X0I4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubulin-specific chaperone A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003905</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TBCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671838.1">
        <property type="nucleotide sequence ID" value="XM_066808220.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041280"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004226">
        <property type="entry name" value="TBCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036126">
        <property type="entry name" value="TBCA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02970">
        <property type="entry name" value="TBCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46988">
        <property type="entry name" value="Tubulin chaperone cofactor A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="18"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="190" mass="20874" checksum="D22E46C1F9DA052D" modified="2025-10-08" version="1">MAASLPVYKKKYQHDDFRISRLPAPPSPKAVRRGHRLPRQPTKINSPIAVVQSHSRQTSSPPRSQALALSTQDACALPLKIATDAVSRLTKEEKMYQKELTSQQERVKKLEADLKNGSASEDGNAEFMVKQEQKAIEETKAVFGPLRTRIGEAVSRLEEQIASAEGDSNANADELTKAKEVLASTPKVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0V0</accession>
    <name>A0ABR1X0V0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome production factor 2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ribosome biogenesis protein RPF2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004014</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
            <location evidence="1 4">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the RPF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671947.1">
        <property type="nucleotide sequence ID" value="XM_066808329.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041389"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039770">
        <property type="entry name" value="Rpf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728">
        <property type="entry name" value="BRIX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728:SF0">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="28"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="277"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="317" mass="36061" checksum="8E68457E74C02688" modified="2025-10-08" version="1">MLRQVKPRNARSKRALEKRAPKVVENPKTALFLRYTTCSEVCQNALSDLYALRTPLAKRFTKKNDIHPFTDPASLEFFSERNDCSMFVFASSSKKRPHTLTLGRTFGHKILDMIELSLEPETYRQMSQFKTRKPAIGLRPMLVFSGTAFDSPTANEYTMAKSMLTELFTGDTSGDKIDVEGLQYLINISADEPAGDEVKPAIHVRVYMISTKRSGHKVPRVEVEEVGPRMDFRPGRIQEPQEDMWKEALKKPKAGEERTKKNVSTDLMGDKLGRIHLGRQDLGDLQTRKMKGLKRSRDMQDEDTAMAEDDTAKKSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X138</accession>
    <name>A0ABR1X138_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Xylose isomerase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004113</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672046.1">
        <property type="nucleotide sequence ID" value="XM_066808428.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041488"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00152">
        <property type="entry name" value="Nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00587">
        <property type="entry name" value="nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002199">
        <property type="entry name" value="PRK01060.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445:SF0">
        <property type="entry name" value="APURINIC-APYRIMIDINIC ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="ENDONUCLEASE IV ENDODEOXYRIBONUCLEASE IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="9">
        <location>
            <begin position="112"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="404"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="406"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="454"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="465" mass="50428" checksum="4FCA4159BCE17BBF" modified="2025-10-08" version="1">MPPRQSLCSRRAVAEEEEKAQVKSETPEVEDAKASRKARPTKRKAAVEEDGGEVGKAAGKDAKPAAKKTRTAKTKIEDIMPLAKRTAVSSLKRAMYIGAHVSGAGGVQNSVHNAVHIGANAFALFLKSQRKWDNPPLAAEARDAFRSLAKAHDFDAHRHCVPHGSYLVNLAAADRAKADQAYASFVDDLHRCEALGIVLYNFHPGNTNGEDRAEAIGRIAAQLNRAHKATKGTVVTVLENMAGQGNVIGCRFEDLRDIIAQVDDKSRVGVCIDTCHTFAAGYDLRSPEAFAETVKAFDDVVGNKYLRAFHLNDSKAPFDSHRDLHTNIGTGFLGLRAFHNVMNHEPFQGLPMVLETPIDRKGADGKSVEDKQVWADEIKLLESLIGMDPESDEFKALDVKLQAQGEGERNKLQTQADKKGAKDAKKAEKAAKPKEGAATKKKAPAKGKKKAAESSEDESDAPQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1C1</accession>
    <name>A0ABR1X1C1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004194</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672127.1">
        <property type="nucleotide sequence ID" value="XM_066808509.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041569"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05286">
        <property type="entry name" value="QOR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047618">
        <property type="entry name" value="QOR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF13">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="17"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="35102" checksum="1C38AB55B5CC2181" modified="2025-10-08" version="1">MASIPQTMSGILIEEPGDAEVLKWKTDLAVPQLSEGKILVKNEWVGVNYIDTYFRKGLYKAPMPMITGGEAGGIVVDVHPSVSNIKPGDRVGYLSSTRGSYAQYNLPDNISTQTAAASLLQGLTALTFIREAYPVKAGDWVLVHAAAGGVGSILCEMCSSIGAKVIGTAGTPDKMETAKKNGAEWVISSRKPQDELVAEVMKITDGHGIDCVFDGVGAATFEADLQLAARKATVCVFGNASGAVPPVDPLRLSAGTPAKNLKLMRPTLFGYVVTAEEFDKYATELLGMIEKGIVKLEKTSTYQLENAKQAHIDLESRKTTGKLLLQVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1L7</accession>
    <name>A0ABR1X1L7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004276</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Peripheral membrane protein</topology>
            <orientation evidence="1 8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672209.1">
        <property type="nucleotide sequence ID" value="XM_066808591.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041651"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="9">
        <location>
            <begin position="23"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="10240" checksum="04E1C25803AD9268" modified="2025-10-08" version="1">MDALNDHDLEKLNDKDKAELRLFLNNENQKARVQSTVHSLTDMCFKKCITSNIKQGKLDKTEEGCMANCADRFLDISALTMKHLQGLRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1Z2</accession>
    <name>A0ABR1X1Z2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672238.1">
        <property type="nucleotide sequence ID" value="XM_066808620.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041680"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07609">
        <property type="entry name" value="BAR_SIP3_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13280">
        <property type="entry name" value="PH_SIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039463">
        <property type="entry name" value="Sip3/Lam1_BAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042067">
        <property type="entry name" value="Sip3_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14248">
        <property type="entry name" value="CYCLIN Y, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="312"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="7">
        <location>
            <begin position="922"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="471"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="554"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="861"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1333"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="494"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1400" mass="155627" checksum="B4AA6657FE614CB2" modified="2025-10-08" version="1">MSDTGAAPPPTPTPSQPVAQRQPSPAIPVILNEAGLDSPSFRANSLHFSDQVDAIERWLDAYAKAGGKLSHDVQALEATVNEYLSKIIPPINVTSVDHDYTALALKRLSEGSREWWTQVVSVARKIDTMSAEPIRNFLSSDLRSFKETRRALDQTQKTFDTTLARYIGQSKTKEPSSLREDAFAVYETRKAYLKASMDFCQMAPQLRFTLDKLLVKVSSDIWREMKRSRDTSGSFAKWGHEMDRVKGWSKEMESTESSFKRELQAARREVGEMTLVTFKPARELETYSASTVPFLGSKGPMNVTTEGQAATISEKQGWLFLRTLSGKPVRTNWVRRWYYCRDGIFGWLVNGPQGVLQGDEIGVLLCNAKPAVGEERRFCFEVKTKNQSLMLQAETQQQLMEWLEVFEVAKKRAFEASVGRDNSSLPGGVDPAFAITPPSMPEFSAKSLDAQLGPDDGPSTMDRVNTLAVPGSDATRTSFDVGTAPKRSATALMTREEGESGRDHAARIMQKLDLHRKANFSSSTDTGALPPPPAGGIASLISASHGLLPGYPAPVIGQTASPRQHPQGLPGPEPQGSNLAPTTLAKAPATTSLSRTAVVYSGDRALNTDSGQNLPTAIMANYWGSNAWARQYAPRQNRVDTSPDDPFGPNTPLIRMSPATDNGDLKTPTSATHKKAISMDAKIIPPPSRDNLPQEQFPDDYPIELKTNAAQFRLLFPSVPLDEKLVLVFRAAWSSTSDAEKPASNMAGNGRIYVTSDNMYFYGHQMGLVIAYTIPLDAITEVTAAPGKDCDFIFLHLSQGMGGSGYSRITIKTFLEDLDLLHSRLNLLVDDLQAEEPMDVPELVKTLINLQHSDDYDKRSPSIDSWEEVSPNTPADNGTAIGRALSPRSSDLMYKSRSRGPRRAVPKLQLPTHPVHYEPEDMQRKVAERHFEISAKACFHVLFGDKSFVFPKLYFERRAKQIAQGPWTTQESGQMQRLFRFNVEYHTMLGQSRAEEIMDQQTIDVFSDHVTYVVTHVKTPWHLPHSRDFKLVTKTIITHVAKSKCKLAIFTKVVWSKAPTLSKNMIERQALDDAAQDAEELADVATDQVRKIGPHGRTKRAIQIYGNIGQQTQVVLFTPGESETSKKAYINPRTITSMVIETVRSFTESVASSLMMWTFAGLKKIWDIVSAERILLAILAVSVLTNVVFSSQGTSTWWNERKAMKFMGRLGVGPNVMMSKAVYLVDLDQAARSSALQPSWPQDSYCYSTFQSIANSSDIDAPYEDTGASLSGTSRTTARRLRRQRQKLGSYRHDLLVAMRMVNSVEREMIQSEWENWLLDENGRCDQVRLALAEADTPDSSSSRSKKNKGKGGAGEQKVLQDKGDDKKREALKLWHEEYCGSCKQDQDALLLEREALRMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2E7</accession>
    <name>A0ABR1X2E7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-psp endoribonuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672482.1">
        <property type="nucleotide sequence ID" value="XM_066808864.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041924"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00004">
        <property type="entry name" value="Rid family detoxifying hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803:SF58">
        <property type="entry name" value="PROTEIN HMF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="125" mass="13373" checksum="31E12F88209969C8" modified="2025-10-08" version="1">MAEMTQVFAKDAAPPAGPYSHAIKTPTAIYCSGQIHLDASGNMLQGTVGEKTALCFQNLKAVLAAAGSSMEKIVKVNIFLADMSDFAAMNEEYAKWMVHKPARSCVAVKQLPKNADVEIECIALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2E8</accession>
    <name>A0ABR1X2E8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">26S protease regulatory subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004556</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672489.1">
        <property type="nucleotide sequence ID" value="XM_066808871.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041931"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048723">
        <property type="entry name" value="OB_PRS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21236">
        <property type="entry name" value="OB_PRS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="26S proteasome regulatory subunit 7-like OB" evidence="8">
        <location>
            <begin position="98"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase AAA-type core" evidence="6">
        <location>
            <begin position="230"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="AAA ATPase AAA+ lid" evidence="7">
        <location>
            <begin position="363"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="48385" checksum="25E3A29E64BDBE1C" modified="2025-10-08" version="1">MPSATGQNWEKYQKKFADDEIEEKKITPPHRRVRFPDPNMDIQVLKTYGAAPYGNALKNLEKQIKEKQQSVDEKIGVKESDTGLAPPHLWDIAADRQRMSEEQPLQVARCTKIIADEKDEQKSKYVINVKQIAKFVVQLGERVSPTDIEEGMRVGVDRNKYQILLPLPPKIDASVTMMTVEEKPDVTYGDVGGCKEQVEKLREVVEMPLLSPERFVNLGIDPPKGALLYDATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELITQLDGFDARGNIKVMFATNRPSTLDPALMRPGRIDRKIEFSLPDLEGRANILRIHAKSMSVERDIRWELISRLCPNATGAELRSVCTEAGMFAIRARRKVASEKDFLSAVDKVIKGNLKFNSTATYMQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2U4</accession>
    <name>A0ABR1X2U4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein 33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004672</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATG33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672605.1">
        <property type="nucleotide sequence ID" value="XM_066808987.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042047"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051668">
        <property type="entry name" value="ATG33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37278">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 33-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37278:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 33-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="219" mass="23042" checksum="63780982FAD75532" modified="2025-10-08" version="1">MATTKVSVLKFVGTVSLGLLTGVSYTLSTLTIPSLLDLPSASSAAKAFGGVSKSATFHLNALTGVAGSAFLLAFTLSPRGYRHPYLLYTSLFVLGTKLTDFVTPSIFGTDASDASSRAARRRRAAAATARKEKQAARRMEASYEVLGDSHSDEGAMSTSGEELDEDTNGEEVRSEVELFVKNQIMQTALAGVGFTMAVLGLWGDGAHRVLGGDALIIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X487</accession>
    <name>A0ABR1X487_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-mRNA-splicing factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005128</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in spliceosome maturation and the first step of pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the SPP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673061.1">
        <property type="nucleotide sequence ID" value="XM_066809443.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042503"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045166">
        <property type="entry name" value="Spp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026822">
        <property type="entry name" value="Spp2/MOS2_G-patch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818">
        <property type="entry name" value="G PATCH AND KOW-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818:SF2">
        <property type="entry name" value="G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12656">
        <property type="entry name" value="G-patch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Spp2/MOS2 G-patch" evidence="6">
        <location>
            <begin position="232"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="255"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="112"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="302"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU369096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8090167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="361" mass="40583" checksum="EC7CF319C8E355EE" modified="2025-10-08" version="1">MSGSENHAQAPRIAIKFGSPSASSSRPTNNKKPQPSSSLGKRPRPHALGGDSESEDDTYSGKHEAVTSFGARGAQNDRQPRDAKSARTSSRPLVIACQNNRDWKASAKSKRPGREVLPHEKEARFSGQSKETEPADQDKEIKWGLTVTKKSADTDKSPAEGDGPEPAPRNPENSTPEEDGQSKTEGRVDADRDALNALMGKDDERKKKIVIPAASNTTEDDALKRDYQTAADVSTLEEYDQIPDGEFGLAMLRGMGFDGKSQGSRPKEVKRRPALLGLGAKEDEEIKKAELAQKRGHRERRPRLDEYRREKEKEKERRHRDSSHSYKSERERDRGSHGDYSRRHDDRDRDSRRHRDRDSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4D7</accession>
    <name>A0ABR1X4D7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673165.1">
        <property type="nucleotide sequence ID" value="XM_066809547.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042607"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF124">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="285" mass="30272" checksum="D0CB1DED32FFDFB4" modified="2025-10-08" version="1">MAGAVFRLPGVAYITGAGGTGIGAAVAKAFARSGCSRIAITDINKKSLDSTRDAILKINPKAQINSRDGDISDEDFVNSFVADISKTFSRVDYAVNCAGILGENLRSHETKASAFDLINKVNYKGTWLSSRAALSRMLQQEPLSEHPRQRGAVVNIASQLGVVARPNAGEFGGWVRTSIKRATDAFVAPYCASKAAIINMTRSDAIDYSQDGIRVNCVCPGVIETPMTTGSAEVTERLKPAINIAPMQRMGTPDEVADAVLFLCSPQASFIQGHALVVDGGYTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4J9</accession>
    <name>A0ABR1X4J9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">C2H2 type zinc finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_005233</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673166.1">
        <property type="nucleotide sequence ID" value="XM_066809548.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042608"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF10">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="194"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8090272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="864" mass="95891" checksum="50F544FD1FC03B17" modified="2025-10-08" version="1">MEAQTTSAQRPGGGGASNGRRRRGAAAKGNTHMPTLWPDLQAFRAQGAPYTKEKPFICHCGAAFTRRDLLTRHQRIALHEKTPDGPPDNASDKGHQTSGVDDMAAAAAAASLSGMSMNPWAHQSQQPLGANGYRTDPRLEDPQGIIGQPYQQPLLPQEYYENGQDMAGFDQFREFANFLDGVGLPAEWSPYFQPDTENEMLDPELRDSRPESDLTAPNGRAGTPFSYWLPSAPEKSKLSEGQSEHKPRGVETVSTPFRVTEDQRDCLASHLESFRDVIDADFVLPSRHALTRYVTSYFQGFHLHMPFIHQPTWMMHETAPELVLAVATMGSQYCFEHRTSERLFRAGKAVLMERLLLENSRFGPKTKTFLNIHNYCPVGGADCNSHMDGIARDRGPWAPIDTVRALVILMGYATWERNEKFVVEAFSLQSLLVQVLRDIGLDEEPEAGSISDPKSAWLAWVHHESVRRTKLISFTFLHTHSVAYNVYPVLRSNEIHLRLPCCTAEWKALSPAQWQLARCETRKEQLNFQDALSSLLRFADGTAPLDPIPTPLGNYVLLHGLLQRIHIVRDLSLPIMDQSASLPPEEVNKLERGLRSWTTGWQQAPESSLDPNNENGPIPFTSSSLLGLAYVRIYLNLGPYRQLETRDPARIARALCRAPSVERSDGVISALLYAAHALSVPVRLGIDRVARSQAFFWSVRHSLSGLECAVLLSKWLLSLQESGMDVPLTDSEDRILHWVRCIVEEAYAVVDFDDDNSNNGCSGEEELDVPTEPGSLSLAVLKIWAHFFKSNTQWPFINIIGKSLEKYREILQRGAPVAVAANASNNTITNGTVQSAVAVPPMVVPVPVPVPTLTRMASAATSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7Y8</accession>
    <name>A0ABR1X7Y8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase AflY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673556.1">
        <property type="nucleotide sequence ID" value="XM_066806260.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039320"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870:SF7">
        <property type="entry name" value="BAEYER-VILLIGER OXIDASE MDPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="455" mass="51055" checksum="D4BF12FF5CD344BC" modified="2025-10-08" version="1">MNSSPITLSPDHVGMVRVPNIKSESLQECNRLLQKNHEEYHMFFRDTAGHNHIAHSLLTCLALGASPQELQERYDDGTPIQRPMPEIDSVLLEKLSDPDAFHAALGVVDRYHTFLEFFKRQIAARDWRAVIQEYVLARTPVADAMLARMYEGAYHPIIHLGLGIEFEQPSIVAESLAQAAAHDDSHISILFASAEAEAGILYPTHGKPKPLIDLVHAVRASDVIRTAPRWTDFGNKMRDGVVGRACEEMSSLAAQFQIATNDPAAGERELQRRTAEMINVAAFFAGAAQRAGRKRKIDFFYMHAVTSSFFFTVLIRQDWIALADRARLVEWKARLDLAWYAVSGSAALDADVVSGYVGGAGSSDGMGWDELFRALCQEHDDGHAAKFIRALKNGEDVCKRYEEDGEWAAYFPMKGDMWLRLARMCQDTTKDMPTDLKWVPFTGFEQPWKRPDLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X871</accession>
    <name>A0ABR1X871_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-lysine N-methyltransferase EFM5</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFM5</name>
        <name evidence="6" type="ORF">PG997_002020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673631.1">
        <property type="nucleotide sequence ID" value="XM_066806335.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039395"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03187">
        <property type="entry name" value="Methyltr_EFM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019369">
        <property type="entry name" value="Efm5/EEF1AKMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041370">
        <property type="entry name" value="Mlase_EEF1AKMT1/ZCCHC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13200">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13200:SF0">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10237">
        <property type="entry name" value="N6-adenineMlase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8091659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="238" mass="27618" checksum="D534164BD208E816" modified="2025-10-08" version="1">MADFDDEPITLSAGALDALKEFYHERDVHVEKFEKLKTQADAVEILSMRDMFKEDWQESQFWYSDDCATLLAEQLLDGATEETTIAIVSAPSVFVAMKNILNASDYSLPKPKLHLLEHDRRFDVFPEFIYYDYNHPLKVPLELKGSVDRFIVDPPFLNVDTQTKTALTIRHITKSVHPEEARAIICTGERMQDLILRLYRSFGVHTTTYEPEHHELQNEFMCYANYEGSKWGFKTAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8S6</accession>
    <name>A0ABR1X8S6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673745.1">
        <property type="nucleotide sequence ID" value="XM_066806449.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039509"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF147">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8091773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="57898" checksum="95AC263CF2AE6C8D" modified="2025-10-08" version="1">MESFILSILRLAGLYMLYRLGIALYNISSFHPLYKFPGPRLASMSYGYEAYYDLWLGGRYTLRIKAMHDEYGPIVRINPDELHCADPDMLDEIYTGGNRPRDKWEHYTAFMIGGLGLSSFSTISHDMHRLRRGAIARYFSRAQMLKLESEIRDFTVRTVDKMHRCAANGEFDIKEVFNCHTADIISQYCFGEPMGFTDQAGFEPNFGTWVKSFLKTTYLTRFMARFVPGVNALANVAPRFANFMGEDVRNVFDQQEVQIPRHIKRAISNKEDGRVFTELLNSAILPESDKYMRRVASEGFLLLVAGTETTASTLSYIVYHLLANPTMMKRLQAALEGVDLINPKWTDLERVPYLWAVLHEGLRLTPGTAHRSARKAPDEELVYDKEAFYYTIPKGTPIGMTSTIQNRNTALFPDPDEFIPDRWLFSTGQRNYALEKKLLSFGRGSRVCLGMELAYCEMYLMIAELVLRVLPRARLVNTTADDVEYDHDTNVPTPKNGLMAVRMVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8Z0</accession>
    <name>A0ABR1X8Z0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nonribosomal peptide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002282</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673893.1">
        <property type="nucleotide sequence ID" value="XM_066806597.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039657"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45398">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45398:SF1">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="5">
        <location>
            <begin position="36"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="217"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="508"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8091921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="779" mass="84227" checksum="BDF0A830F58C3F21" modified="2025-10-08" version="1">MSAAQQDRILSLAAIGPSRLEDIAKKCRVPVSSIEDVYQCTPLQESMIAANRDEVFHFVLTSDRGVDVDKFCTAMRRVVAANAILRTRIVECDDELGGGLVQVVTNEDHVTNLNTGFGSVDEYLYGDAGAAHHFFAPGEVLFRSAFIGESLVTTMHHTIADYWSMDKMLQLDMPAVYFGQPPIKRPAFRDFVTQCLRVDRAAADGFWASRIRGSPAVFPAPPKPPTKGRLSSTGRPDAGGAVSEKPSRMMPLRRSAPGPGGISPSHMAFYIEAAWALTAAIYTDSDNVAYGYVISGRSPNPDAVENTLGPTVTEIPIQVSVPRRMTVEKLIKERAASWRHLQQNTLFLQYGLENISRVNEAAKAAAGFGALINIRPSVFTDKNKDTSIEGPDDIKLRMVWLRGYFPLQFIFSITEEGVMVWPRTNPSIVSDAQLDRILSQYEHILRLLTETTPQTKLGDLPLLDPQAQSAIVLRNNQEAFVPGAAARCIRDVFSGPALARALRSWDVNTTTPATTNGDRDNSELHTSQGGTHVGNTVITPEGCGIWITIPESVDRLAPQGGIGEVLVEGTASGAEDDAVTESLVILTPKWATSIRGEKATSSKFLRTGILAKYALDDDTGSVNQLSLIGRASNRIKFGGQSIQLEELERAIAARCDAVRDVVTATRIAGGRTVLVAVLCLADSMLPRGTVLGRLPPPAAAAGISSDSSGGSDDHATTMRTRVEAGVHAARTWAQRASGLPADRLPTIWLAVEELPRVQGSSRDVDRVAVQQWLAVAMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X994</accession>
    <name>A0ABR1X994_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002397</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674008.1">
        <property type="nucleotide sequence ID" value="XM_066806712.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039772"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="20"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="257"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8092036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="388" mass="41985" checksum="918132962B229BC1" modified="2025-10-08" version="1">MGAAWHPEEELAGHHIHLRGNFQYGGEDTPYLIPGEWVQRTQDHIVVTFNYRLNIFGFPNAAGLPANEENPGLLDQRAAVEWVRDNIAAFGGDTKRIGLWGQSAGAISVGTYGYAYPDDPIVNTQLMDSGSEFFPAPILYTATADVSHSNFSFVAAHVGCGSLDPAAELACMRKVDALVIENFLQEYQDNLTQPIITFTPIPTLIGTNAQDGNAFVPLGINGVNDTLANAVTFGYFFCPAYKSAAQGQFTHTRGWILATVSRLASPVYRYLYSGNFTDIAPKPFLGAYHESELPLIMGTYQLYGGAPTEFERQTSALMQDSWLTFVASSGDPATMSAKVGWPEWTSVDNGLVRSFAPAPAVTATNVSLHNLEVLCPSLDQPSGNGLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9G3</accession>
    <name>A0ABR1X9G3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="4">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002424</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674035.1">
        <property type="nucleotide sequence ID" value="XM_066806739.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039799"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF30">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="5">
        <location>
            <begin position="5"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="6">
        <location>
            <begin position="196"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8092063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="36330" checksum="DD9702928AEA6C51" modified="2025-10-08" version="1">MAPRILVFGTGSIGAVYTYLLSKAIPASNITAICRSNYEDASKYGFTIQSTIWGNDLNVKPRIARTVEEAVALSNGEPFDYVLVCSKAIPTTQSTAELIRPAVSTSEQHKTAIVLIQNGVGIEEPYAQAFPENPLISTVVYLPATQVRPAVVEHKEVELLHVGTYPADADADAKKAASVLVELLTAADATAKLHDDIQAQRWTKLLVNASWNPICALTRSRDHGFLSSGSNDGEEGEPLEFIRDVMGEIASVAQAYGYGNVNEEMIEFQIGRASVRKAPGIQPSMMADAMAGKSLEVDAIVGNVVRLAKQKGVAVPMLRTIYILARGLDSSLSRQEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9I9</accession>
    <name>A0ABR1X9I9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000009</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674097.1">
        <property type="nucleotide sequence ID" value="XM_066804324.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037384"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="3">
        <location>
            <begin position="35"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="87"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="309"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="402" mass="45065" checksum="A75FF6728E1508A3" modified="2025-10-08" version="1">MTRPHKDIYGKMEVFHRSVERSRHLAKNAIGLATLGDRIVMYTDGSVRLPEYDCPRTSAVTYRHVYDGTDAKNAPWIDRAFGVLGIKNSNEAEIVAVAESLKALEQEVRSYIEIKKQQAKKASRLQVLIFSDSRHCLSILDRMLQTLMKNKPFTGRDWTVEYLKANVKKLVETVASTDLDLPVEFHWVKGHSGVEGNDRADWLAYDAYPTAKWYFLGHQSSACPAMYEVAEMGEMSMALVERQQEAESLEPSVTNTPSTATTSASQMPPETVNSPIALGAIESVIDSTKPHPEPRETDTATAGQTTAALSAVYNTIADLRREVREQREEERKQSEQMVSKFLEAMKELKKAPHVTTTPVGGGEVADLEPKPENQRKRNFLVAKIRRAGQRLRGMGRKSKSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9R2</accession>
    <name>A0ABR1X9R2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone deacetylation protein Rxt3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674106.1">
        <property type="nucleotide sequence ID" value="XM_066804333.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037393"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052793">
        <property type="entry name" value="EJC-associated_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013951">
        <property type="entry name" value="Rxt3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46589">
        <property type="entry name" value="APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46589:SF1">
        <property type="entry name" value="APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08642">
        <property type="entry name" value="Rxt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="768"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="470"/>
        </location>
    </feature>
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        <location>
            <begin position="510"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="595"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="624"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="718"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1044"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1224" mass="134358" checksum="4369485E368B06EC" modified="2025-10-08" version="1">MDSRQPLHHHQPPPPPQLQQPQQPQQQPIGVPFARTAGASPPYGRSPFPHGPNPATTPSPYPPASHPQAHPPPTSPAGSVVAAYEHQHQRHPSDPGFFAHQAARATYAPTTPRIPRPYPSQHGASFTAPDLATAPATIAAATPVADAAHRPPHEPLRAPICVARTPVNLGPPSAFPAGRELPALNSIPRTGNAGGSMSISAMLGGGGPPHRESTPGHPSNHTAFPPPPTTTAAGPGPGPAYASSVHASPRMQNATEYNGYARGPQTPPEHIRPYDARDQRGSVAGSPPQAMYGTPEVARFGTPQAYPQRGPPMGPGDDRRDPSGRMSAASVPPRPSSQPRAYAGMPGRPVEMGRGPPPQPQPQPGEQMFGRRDEMRPGQQEYNPERVPRPMSFEEQRRLMERDREIRDQMDREAEYRERERMERARFEEQQRPFMAERERMERERMERDRMDRERELDMMREHGMRERTSSDPNHPHAQQRPVDYGPPGPNGHKPPQGPPPYGRMDPREAAAWQQQQQQQQQQAQAQAQQQAQQQQQQQQQQRPGFDQPPRGHYDQQFPGQRPNDYPVTNGPVYDRYPAHAQPPMERYPPGGPPSQGMPMPQQGQAGPPPPQPYDSPERHRFAQMPPHQQQQQQQQQQQQQQPPLHQQHRPRPNEEGPPPPSIAYNNGGQGTLLYEPSRQQPRPMDEGQAPPLMRQQSNNGLLAIGEINRKGRVSPLPQAVQGAQPQHQGPAGEPGIKSEFGRMFSGIGSGASGLGFSSPVLSGATMPFTNSGLARRDDVEPPHNEGPPEPPVKAVRKRNRKPKDVDGSKGEDDDNSTGRNTPVGRAKRPKTHAHHHHHHAPLKNMKSTTPIPSPTGLPKDFGLTHNHQIPRSNGAGPTSAPKQAVNTTPVIVPKTKRSVNSQAVLDSVAHKPRKHLGDVVYDSSLTPAKLMSPSRFGFASTPRPLPMAMIRDNENSTLTVKIPRAHLTAVAREEITTRRAIWGTDVYSDDSDVVAACIHAGWIRGEWSNDIDTDLLDLRVQPTKAKGRNAAPPAAADQGPQEVLTSPPSTGPVQVPHHRDLHVTLLILPALEKYTSSTRFGIQSREFGGTYNGRKSSHDGISFMITAIRWVDGAAPQSRLRGKARRERIRKAMSEVQRAHVLDIGEETRRSSSCRRSCRRRRRLRRFRHPVNGSNGVAMDAKPSSSPAAEKAHQEEVREPSSHTEGPAKVDVVPAAVETAKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAJ5</accession>
    <name>A0ABR1XAJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Geranylgeranyl pyrophosphate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674498.1">
        <property type="nucleotide sequence ID" value="XM_066804725.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037785"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="66" mass="7682" checksum="53469AE55E9B8657" modified="2025-10-08" version="1">MFCASWCAAAGVFYVVEMFTNEAAQEHHHNQLYTAELRRISQEEHNMAKKVEVQVLDRFAGFNRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBH2</accession>
    <name>A0ABR1XBH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteinase inhibitor, propeptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674747.1">
        <property type="nucleotide sequence ID" value="XM_066804974.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038034"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052471">
        <property type="entry name" value="PBI_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288:SF1">
        <property type="entry name" value="INHIBITOR I9 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046971537" description="Proteinase inhibitor, propeptide" evidence="2">
        <location>
            <begin position="20"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="10620" checksum="B8BEF08047350A1B" modified="2025-10-08" version="1">MRFFASVVAALAVAQGAVAVDVQKGIIVTFPQETADDVMTRAKDEITNAGGVITHSYTLFKGFAAKAPQKIVESVTAWSTQYNAVIEEDQEVKISNNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBM4</accession>
    <name>A0ABR1XBM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674766.1">
        <property type="nucleotide sequence ID" value="XM_066804993.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038053"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045987445" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="19912" checksum="6746276DCFC2AD59" modified="2025-10-08" version="1">MSVLKNIIVQSLLATAVAAMPLTPEESSTDVGSQDAINAVWSHTLVARKNPDKCEAHIAIDSSNGLCGTRCTDKYKIDIVDKDGQAIGKTYDWSQVGQWGATNPPRKVEIPTTKDKSFWLDGTLPSGFQSNDGPWRSSFTLTYDTQVWNSHECPNYKYKAPATSNGYRHQFDLWCEFDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDC8</accession>
    <name>A0ABR1XDC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675463.1">
        <property type="nucleotide sequence ID" value="XM_066805690.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038750"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF102">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="38328" checksum="9B214AA366763170" modified="2025-10-08" version="1">MPPPMAGYDTDTYGRIPTPFSIYDNDPYYGSVTEPSSGRTYQNFKPGRYPLPNDDAEQDRLDFEHTLIRITLDDRLYLSPIRLDRTKHVLDVGTGTGIWANQFAEENPQTQVLGIDLSRIQPSRLPNCTFSRVDAEEEWMYYPLKFDFVHLRGMSSCFDNPRGVLRQAFLNMNPDAWIEFQDVSWHLFSDDGTTEGTYLERNRQLLSAGAQAMGRDLHWILYVKDWLKEYGFVNIVHKQILLPLNGWPREPKWNLIGRYVEEDLCMGLDGMSRRLLTAAGLRESQIDELMSLARNDIRNTNIHGYLPFHVVYAQKPSREEMTRCGAAEPHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDD7</accession>
    <name>A0ABR1XDD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001273</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675361.1">
        <property type="nucleotide sequence ID" value="XM_066805588.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038648"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050596">
        <property type="entry name" value="AspAT/PAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="90"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="50104" checksum="F84A20B3A4C7D938" modified="2025-10-08" version="1">MFGNRKFSMNRNTGVPRMSRRFSVGEPNTSETSSKIHRQFRAAHEGHLPHAGLDASRASTGVVWCTERASEYGFLEAPMNGQTWTIDVSSAAREYGPTAGIKPLREAVAHLYNEHHRQGKESKYTWENVAIVPGGRAGLIRIAAVLNNAYVAFFIPDYTAYNELLSVFKNFAAIPTPLDESDGYHIHPDKIANEIARGTSVILTSNPRNPTGRVVANPELAEIQDICRGRATLISDEFYSGYNYTSDCDGTTISAAENVEDVDEDDVLIIDGLTKRFRLPGWRIAWILGPKEFIKAIGSCGSYLDGGANAPFQEAAVPMLEPSLVQTEMVALQHHFRAKRDYVLRRLRDMGFVIKYVPDSTFYLWLNLEGLPGPISDGLNFFQACLEEKVIVVPGIFFDLNPSRRRDLFDSPCHHFIRFSYGPRMETLKLGCDGIERVVQKFKKFQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDT1</accession>
    <name>A0ABR1XDT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001444</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675532.1">
        <property type="nucleotide sequence ID" value="XM_066805759.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038819"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="4"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="255" mass="27295" checksum="AFCEB1B6D3B05CA1" modified="2025-10-08" version="1">MEFNRIAVYGHRGWASSAIVKALIASGAPIRVLHRPGSDISMLPSASNVTTVAVDLDDQPALVSALEGIDIVICITGQTGVPLQHAFVKAIPQAKDVKLFVPSDFAWRHSPQGLRVLVNKVKDEVERAARDAGIPTIVVLPGGFAESFLAAGLLGVDIAGNRIVQTGDSSHCQANLCTREYVAAAYASIFARTPAAQLANRDIGLCEVRATGEEIRAALEKRHGGVPPQVIVNDLERVDREIETRIAGGRRSPWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEJ9</accession>
    <name>A0ABR1XEJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001648</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675736.1">
        <property type="nucleotide sequence ID" value="XM_066805963.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039023"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045797471" evidence="3">
        <location>
            <begin position="18"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="390" mass="42726" checksum="39E7EA5EE94C15D5" modified="2025-10-08" version="1">MSLLLLAGADVAKGALAQQTGGDSWLPRPFSGILAAVGDKTFLPAPELPAVVMSTEWSYHRTNNSWVINRLLRDYEEYWMPRQVKERLTQMLAKAGDRGRCRAGLCVSVFEASSEKIAGVPDRDLLWYSGYAVAVLQLAIASIPWALYGVWQEFAVTALGTALAFLTASLQHWTQERWACNKNSNKTFVLTRGNGAQHAIVIIGAGRGLDLEDLATSSEGLPGKQSTPIIYSGLAVLWCVLLITLAFQSAMQHGDCQRIIVATVCGIENLTWFLLAVGTIGMIHTIIIAGAPRKPGLFGIHLTYRDVFAQPKVMKTLQELEKSYPGCGRSMIKTFFPGDLWEDEQTWWQAARERERAAKKGAPHSMLPEIPTTKIEESSGPSGMSSSTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQK3</accession>
    <name>A0ABR1UQK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_015403</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660602.1">
        <property type="nucleotide sequence ID" value="XM_066819717.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052777"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12676">
        <property type="entry name" value="RRM3_Nop4p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034808">
        <property type="entry name" value="Nop4p_RRM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="59"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="175"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="356"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="530"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="254"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="568"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="676"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="254"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="312"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="686"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="715"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="760"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="778"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8061182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="795" mass="88161" checksum="37FFED70A85EA58C" modified="2025-10-08" version="1">MAGPGKLKRSRDQSDSSKPASVPSEQAQTATAEDGAGEAAPAGETTERATKRPRVEENRTLFVRSLPPSATDESLTEFFSNYFPVKHATVVKDRATKASRGYGFVTFTDAEDALAARSRLNHQPLDGRKITLDVAEARQRKPKATAEPSGIATETASRKEQRVADMEEARKPQNAKLIVRNLPWSIKTPEQLSALFQKHGKVKYADVPQSKGKLAGFGFVTFRRHKHAEMAMEGENGKMVDGRPIAVDWAADKSEWTKQQKGDAPEETTPKKKSKKAEAEADEDDAPEDKEDSEEEEEDEDLRNFMKNQMENMEDEDDEEDEDDEEGDDADFDGGAEEDDEEEEKPAKRLTTNNDSTIFIRNLPFSVDDEALKTHFEQFGPVRYARCVMDRATDRPAGTGFVCFYSQDDSTACVRGAPRQQLPDNPGKRSILQNEMADLAGMYTLDGRVLQVTQAVNKSEAQRLTETGIAARDTKDRDKRRLYLLAEGSIPSGSPLHSMLSASEIQMRDESAAQRKKQIQGNPSLHLSLTRLALRNIPRNMTPKELKALAREAVVGFSKDVKAGLREPLSKEELNRGGTDDKEAERRRKEKKKGIVSQAKIVYENAQGSKVDVKDGAGKSRGYGFVEYSSHRWALMGLRWLNGHAVDSPTSKSQRLIAEFAIENAQVVARRKDILLRSTQGPRNPPQEKEIPKNAPFAERRNAFRNAGKPGTRRPGWDGKRPSGDDKKDGKKPGFGDRKPGGGFDGKKPRRSDGAAADGGEGKKSGGDARQALDQKIIARKRNMRKKKATARNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1USV4</accession>
    <name>A0ABR1USV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short chain dehydrogenase/reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_015321</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660520.1">
        <property type="nucleotide sequence ID" value="XM_066819635.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052695"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF18">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G12480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8061100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="322" mass="33397" checksum="71ACC0B917CC294E" modified="2025-10-08" version="1">MDTSKLFRVDGMVAAVTGGGTGIGLVMARALLGAGAKKVYILGRRRDVLDKACAEAAADMKKTSSSTSGVMVPIECDVTSKASLQAAVDAVAQDSGYLNLLVANSGIGGPEARYGKGKSVAELRRELFEGVEMADFTHAFHVNVTGAYFTMLAFLELLDAGNKHAVGHAGDAAEEGSVFGVPAADASANPKVPAVQSQVVFTSSISAFSRAHVSGPAYSGSKAAIMHLTKHSSSNLAEHGIRVNALAPGLFPSEMANGLMEKHGDPSHKEFGHPLFLPSLRFGTEHEMAGTILYLVSRAGAYCNGSIIVEDGGRLGVMPAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTK2</accession>
    <name>A0ABR1UTK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660859.1">
        <property type="nucleotide sequence ID" value="XM_066818671.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051731"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="656" mass="74370" checksum="A6112E65AC6A46F1" modified="2025-10-08" version="1">MEETQSWSMGASLSPEESFDMMRDVGLSGGSQADYYLQVCAMSQGLDATADDDDDISGPDLSSYFTNHTSSGSNAAKDMMATAASPSSADYIKTESEPSQQDGDEDDSDDAATIITPIDYSEARENHWRHAGYHDDEIEPLAWAWSQHQRLIPECQKTGWSWNRTRRDPTARDVWREAYRDLKGRDAPEPPAPRPAPPPPFWMWVSGRWTLVRPRPMERRREPVEEWDWAPVPCECWHCAAHPDRGWEQVRHEPRIVFYEASRYARLGHALFQPEVGSFVFEWEIADTAQEQKRNGWKPHQEQVTLQALLPLCYQKRNKQCHPYHPPVPNTHGVELPARYRICLLTDEYTDWVKALYSDGFLLRVTMWAAMSRAAPPGTSRVHLALRAFTELDCFHRYLVNSGLSYAIFDTEYAFRRAGSAEAGGRVYWGDDGLLLGAQQQQQQNGDGAHGDGDDAAEVDRLVEGMDFPLVCYGLSHDAFAPHPPAIQKVVNTFYPLREPVFEYIHGQLDERPREHPGRRPPAGPCEVLKRNGCITKRGYEGRGLMTALNRFIALEARARGYLFDMDDEEEEEEEGEEKKMVKGKNPMAAAGMRSSFFAYVDDFGKFSLADFGVEEEGGKDGREVYPFRGYGCKEKSWTIWCDLAPPSPSSPPRSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTN5</accession>
    <name>A0ABR1UTN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">beta-glucosidase</fullName>
            <ecNumber evidence="9">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_014391</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660893.1">
        <property type="nucleotide sequence ID" value="XM_066818705.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051765"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="11">
        <location>
            <begin position="388"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="74"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8062294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="827" mass="90124" checksum="34E5EDB3FC6CF38F" modified="2025-10-08" version="1">MADINVEELLKKLTLSDKVDLLSGIDMWHTKAIPQHGIPSVRTSDGPNGVRGTKFFNGVKAACFPCGTGLGATLMRQANGPRSPRQRRPRHPRPDHQHAALPLGGRGFESLGEDPFLAGLGAAALVNGIQSEGVLATIKHFVCNDQEHKRNAVHAIITERALREIYALPFQLAVRDAKPAAFMTGYNGVNGTYCSESEKLLERMLRREWGFEGLVMSDWWGTYSTTESALAGLDLEMPGPSRFRGEMLKFNASTGKVGEHIIDQRARTVLEFVKRSYANGIPENAPEETNDTPETAALLRRVGNEGIVLLKNDNNVLPLKKNKKTVVIGPNAKIATYHGGGSASLASYYAVTPFDGISAKLESAPAYAVGQYSHKMLPALGYSVKSKTGGPGMTMRMYNEAPDVSGREPFYELELVKTDTFLVDFHHPGLKSDLFYATLEGSLVAEEDCAYELGLVVCGTGKLYVNDELVINNADKQTLGDAFFGAGTIEERGTYPMKKGQFYNFRLEFGSTPTSTLQGETVLIRGGAIRLGGCKVIDPQAEIARAAEMAKDADQVIVCAGLNADWETEGHDRADMKLPPGVDDLIAAVAQANPRTVVAMQSGTPVEMPWIRDVGAVVQAWYGGNETGNTIADVLFGDVNPSGKLSLSFPVRVQDNPAYLNYRTEGGRVLYGEDIYMGYRYYESVERPVLFPFGHGLSYTTFAFSDLSVSDKDNKLTVSVAVKNTGAVTGAEVAQVYVAPKQKAKVNRPVKEMKGFTKVELAPGESKTVTVDLDAKYAAGYWDEDRDQWCVEQGEYEVIVSDSSEVSKEKAVTGSFTVKETYWWSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUT5</accession>
    <name>A0ABR1UUT5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipid droplet-associated hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014782</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lipid droplet</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. LDAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661284.1">
        <property type="nucleotide sequence ID" value="XM_066819096.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052156"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019363">
        <property type="entry name" value="LDAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390:SF0">
        <property type="entry name" value="LIPID DROPLET-ASSOCIATED HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10230">
        <property type="entry name" value="LIDHydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="347" mass="39136" checksum="AC50049DBF9A236B" modified="2025-10-08" version="1">MAIHSISFPAGQESRSASRDVLIFMISGNPGLIDYYAPFLSALRTLLDSSPASKGTRFHIYGQDLAGFNDADHESPFSAAHPPRDVAYQVNYLFQTLSEISIPEDGNAGSAKQGKPFDEVILVGHSVGTYLILQLFHKLLREPQAAPHLRLKTGILLFPTIEHIRHSPSGQRLELLRSAAFLERHAHLLASGFLRLWPYAALHWILRTLLGQPPAAADVTARWLKSRDGVWQALHMGLDEMRVIGEDQWDEELWEIEREDAKAAADDDDSDDGAAKRLPPKFFFFFGKDDHWVANHFRDAFIERRQKQAERTRVMVDEGNLPHAFCIHHSEVVAEKVSSWINELYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUU5</accession>
    <name>A0ABR1UUU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014780</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661282.1">
        <property type="nucleotide sequence ID" value="XM_066819094.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052154"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051317">
        <property type="entry name" value="Gfo/Idh/MocA_oxidoreduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708">
        <property type="entry name" value="CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708:SF5">
        <property type="entry name" value="CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="5">
        <location>
            <begin position="140"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="375" mass="40607" checksum="E24142F686182518" modified="2025-10-08" version="1">MASSKQFNVGVVGYGMSAKIFHIPFIKATPLLKLRSILQRSPKPGDSAPADYPDLQHHTALDSLLADPELDVVVLCTTPPTHFAFATAALEAGKHVCCEKPFVPTSAEAAQLAALASKQGKLLCVYQNRRYDADFATVSQLIKDGILGRVVEFETHFDRYKMEHPTNWKGTMPMEQGGGAVYDLGTHLVDQVYTLFGMPESVYAKFVSQRQGKFYPGSTADGGAVDPDSLTAHLYYPDTGLTAIVRIGVLSVETQQPRFWIRGSKGSYTKKGLDTQEPQLKGGMTTSDAKFGREGPEWAGKLAILGEGGAVSQRDLPNVEPPPTYAKIYESFARALASGKEEDVPVPASQARDVLKIIEAVQESGKTGREVPISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVD7</accession>
    <name>A0ABR1UVD7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_015001</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661503.1">
        <property type="nucleotide sequence ID" value="XM_066819315.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052375"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="419" mass="47711" checksum="472F5A7AFAA6974F" modified="2025-10-08" version="1">MVEKAVVVIGAGVSGLIAAKRLIAEGLNVRVFERADGPGGVWLYNADATAPFASPMYDPLETNFPRDLMELADHPWPKNAPLYPSHQQVLDYLRSYSEEVEVEYGTEVVGLVRRTRMWPHRWQLTIKKRGSKEETKLDFDHAVVCIGTFDKPFMPEYDGLAEWQEAYPDTNVVIVGTGPSGDDIANKLSRVAKAVWWSTRGSQDRVAKPRITPAGPIKKFHHKAGTIEFENGKRIAHIDKVIYCTGYHYSHEFIRRGGFRIDGLWKHMFWIEEPSLVFIGVPKEGPTFLISQAQAAYAARHVAGISHLPSKLKMTMNAADELVALVKANVNVEKMPHQLRGDRAKEYIEDLRRRCEEDAAKKRGQLSVDGNEPFEWTDRIDWIMTNRGRLRERYIAKCHFRRNYPTPESLGFKGVPKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWK6</accession>
    <name>A0ABR1UWK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661034.1">
        <property type="nucleotide sequence ID" value="XM_066818846.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051906"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33567">
        <property type="entry name" value="CHROMATE ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33567:SF3">
        <property type="entry name" value="CHROMATE ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="118" mass="12772" checksum="DE89C265223225C6" modified="2025-10-08" version="1">MFGLSIGVSNVGEDLPGPLYSLLSGLNAATEDIITLAAAGLSDRAVTGKLTRIVVFLTAPAGMLYNALWYFHVLVFAAVCATVVHDYRWVPRPVRAARRWVRPGTGTEGQRRDANDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWQ3</accession>
    <name>A0ABR1UWQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TeaA receptor TeaR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660837.1">
        <property type="nucleotide sequence ID" value="XM_066818649.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051709"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="447"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="56052" checksum="BEFD0C9A3DCFC469" modified="2025-10-08" version="1">MTSTRMTRITTRHMARRKTLFICKTKTRTETPFAKRDPNEPFPATKEALAKRDPNEPFPATKANGGRIGRPENKRAHTDGHIVSLDDEENKWIHRDKLAKIESEELQAAGIILPKPRSQSRPRRDRSTDKANGSKRTTDASDHHPVSRSRKNSTQTSGAAEKTSDPDQGGSWDCRRPDEIAEDPNEYWITSESLGPKGSRIPVAKVSPAPIPLDYLERDAPVPRKMSGTLALPDDDFSLTNLKPRSRSNSLVLDEVTKLSSAQQRSTSDNSPKKAPVPKKTIPAAARSASANRTNNTRPKTRSGTGRDKNSTARPGTRSGELSPVAKSPEGEPPWMVSAYKPDPRLPPDQQLLPTVARRLQQEQWEKEGKFGNTYDKEFRPLNEQEHLRPRETQKTQQQPETEPEPEERADEWPLRAGEGRAEAKSPTPSRPGTSSYSTMPRLNSKSSQHPPISSPRSPSIPQQNRMSAAPSQITRVPTQPEQPPVQEKEEAKKEGGCGCCVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1E6</accession>
    <name>A0ABR1V1E6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein TED1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011756</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661763.1">
        <property type="nucleotide sequence ID" value="XM_066816071.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049131"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033308">
        <property type="entry name" value="PGAP5/Cdc1/Ted1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315">
        <property type="entry name" value="METALLO PHOSPHOESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315:SF1">
        <property type="entry name" value="PROTEIN TED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="528" mass="59186" checksum="085944724B3328F7" modified="2025-10-08" version="1">MSPAALLRNALRLLVPICVACTVWLYLYPVFLGCAFPTPADRPDPSTAFHSTLRQHVGSSDNKAADLAPFRLLALGDPQLEGDTSIPNAYRDSFEHLTKAWRHMTFQTHHASLRWRIRQALHDLVDFYMEDIPDTFESVRKRIDLFGNDFYLAHIYRTLSWWARPTHVTVLGDLLGSQWISNDEFARRSWRFWNRSFAGGERVPDDVAAYPASEYDVTGNLGSDHANDIVWQRRLINIAGNHDVGYAGDLTYERLSRFEGAFGKAAYELRFELPVTNATLNATLFDAEANPDSTRLIPELRIVVVNDMNLDTPALISDLQDKTYSFVNDVINTASAVEFQGHFTVVLTHIPMYKHRGICVDPPYFDFHPSEEGGGVREQYQLSADASKGFLEGMFGLHANPDAPGGGRGRRGVILNGHDHEGCDTWHFVNQTDDKSPEERKWDVLRWEDAQADSVPGRAGHPGLREITVRSMMGQYGGNAGLLSAWFDEETWEWKYEFANCALGTQYPGGSSTSSISSPSWGLCSTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1P0</accession>
    <name>A0ABR1V1P0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the trichodiene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661854.1">
        <property type="nucleotide sequence ID" value="XM_066816162.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049222"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024652">
        <property type="entry name" value="Trichodiene_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06330">
        <property type="entry name" value="TRI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="241" mass="26885" checksum="A56FCAB8263D0388" modified="2025-10-08" version="1">MYSWLGLLLDDSAAEHSDEFARFGARFVGGEPHPLPLLQAWADLLRLTYTYWDAAPANFIVTASLNFPQLEPTADGRGVQGIAAAPRRTGVLGFRNSSGRSWARYVREKDGGGDAVAYFTFPKSMYPSQEEYLECIPDLARYINLANDVLSFYKEERAGEDDNFISQMAMYEDKDKLAVVEDLIDDVAKAVARIRATIQGKEPYASAVEDHILGYVAFHKLSPRYRLSEVGLGEEKFKAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V281</accession>
    <name>A0ABR1V281_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662047.1">
        <property type="nucleotide sequence ID" value="XM_066816355.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049415"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03749">
        <property type="entry name" value="proteasome_alpha_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035144">
        <property type="entry name" value="Proteasome_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="263" mass="28817" checksum="2FFF606ED42CC624" modified="2025-10-08" version="1">MFRNNYDNDSVTFSPQGRIFQVEYAAEAVKQGSVVVGLTSKTHAVLVAIKRNAEELSSYQKKLFAVDEHVGLAIAGLTSDARVLSNFMKNQCLSQRLTYDRAMPVESLVQSIGDKAQINTQQYGKRPYGVGLLIAGIDETGPHLFEFQPSGMTQEMVACAIGARSQMARTYLEKNAEHFPDCSRDELVKHGLRALKETLVQDKELTLENTSVGIVGLKEAGKKGLEYFKVHDGPEVKEWINSVADDAEAGGDAAEGEGMQVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2K6</accession>
    <name>A0ABR1V2K6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3835 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012176</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662182.1">
        <property type="nucleotide sequence ID" value="XM_066816490.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049550"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024325">
        <property type="entry name" value="DUF3835"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039553">
        <property type="entry name" value="Prefoldin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052255">
        <property type="entry name" value="RNA_pol_II_subunit5-mediator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111:SF0">
        <property type="entry name" value="UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12927">
        <property type="entry name" value="DUF3835"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13758">
        <property type="entry name" value="Prefoldin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3835" evidence="3">
        <location>
            <begin position="516"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="560"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="353"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="432"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="582"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="594" mass="66131" checksum="572E9469B03F2E84" modified="2025-10-08" version="1">MSTANSFIDVERHRQTLEQNLVKLEEALDEWRQWKSEYEALKKEVSALPASTKNLTSTREAYHGDLVDAKELQDIFGKNDSKTAQQVISVLTNRIDYVSKNISSLENQLEAAQNKYAAADVFSNPNAADEGGLPITEIMEELDDDDNVLSYSLQTPSDNQAQLLEALKKAGLAETPAPPATKPQPPSEKPVEDEAEARATAIKNEAEARANAIKNRQIRVPMRPKVPAQSEPKVKKGVSFAEDTKIEDEEAKDEVQRTQNADQIEELMRQAKAQEEIISEPVIPTDESEEEAQLRRDMLSYNLSELNPVVAELTLEEGDYSGDDFDSEDYSDDEEDEEDEDRWGRSTQSVVDDDYRQKMIEIQERLLDSQKASPDSSAKLYAEDNDGDLQGIGRITIRKDEPTATSGPSASNGDVPVYKTKGVRFASALDVADEKKPSQAEPAEKQPPVTPFVEPLSTEIVERKSSTTADPTQAPAPAPCQESLEVQVEQSSRAPYTWPYQRNRPIAPSGPEGKTMADAVLERDSSTTPKEPDELDAGLLRQEAATEYYKMRNRLIQKQGGFMKEDENPIQPLDEEEGGPKRLSRFRAARLAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2N1</accession>
    <name>A0ABR1V2N1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012192</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662198.1">
        <property type="nucleotide sequence ID" value="XM_066816506.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049566"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="610"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="618"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="740" mass="82200" checksum="99BA2C2D2F8D64B1" modified="2025-10-08" version="1">MKGRDPSATGSSPQKEKAEQTLCREKTLARLEARRSPVLTKFCLQENRAIGRTTQQPGRDPPGHQRRRSARLLQEPPNPADDPHCIPSETFPRPSEPQRATVSPSSSSTPAGTDSSEAYQTVPSYYNQYAPPRCICRAPVGESVESVEDDDVLLSTFVTKLSQSYPFVVLPPGISAQELKATKPFLFIVIRMVATVRHLRSMRAQSFRIMKHIADYMLVRSERSLEMLQAILLVLGWYHYHCMMHSQMSNLSHLATSLCADLGINRPPGLHERTRLLVLHPEQPKARTNDERRALCGAWYVNSCIALSYQRVEQGKYTSYIERCVKELESANEYETDSLLVQLMRIQRLSDKISCLHNKNEDDIELPAIPRAPTSAYLGAFQAELDKFKAQVPRHLRNNRVLSVHICSATLRLWEPPKMDATVLEDLSNSLTSLSIGAPSTLDFLYRSNAALKAWFECWLSIGVQEYFYLTMPLCGQLINAVMLLSRWFKLSSMDPPPTGPPQQPSPQDQRDLSDMIDREDADRPGVPAAALTIKSHILAQPELHLDIVGILRALVARLEEARNALDKAHGGLENNIWDLAAKKIGITRLKLERWAEIVATMGMEGLLARRHERDGSGSEEEVEGEEGQSREDEYSPESRGPLSAAATVDGNAAMEGVEMGSSSNAAAAAVGSGAWPQPPHTPGLIHTEAWMYDSNILANNLFDELGLDQNFFYDNNDYGGTILNSLGGGNGGADQSLHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3J5</accession>
    <name>A0ABR1V3J5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662491.1">
        <property type="nucleotide sequence ID" value="XM_066816799.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049859"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="14482" checksum="F2F6FB887CC220E5" modified="2025-10-08" version="1">MAAADKITTVASASEFDALLGANTYAVVDFHATWCGPCKAMAPVFEQHAAQHASAGRVAFAKVDIDAVPDVAARYRITTIPTFLFVKDGDAYEDIRTASPPKLKAAVEDVAKELAKEGAAAGKDQNEVAAALKDEDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3Z2</accession>
    <name>A0ABR1V3Z2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662661.1">
        <property type="nucleotide sequence ID" value="XM_066816969.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050029"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05262">
        <property type="entry name" value="SDR_a7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF9">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="321" mass="33814" checksum="60A41E5BCDB62C65" modified="2025-10-08" version="1">MRVFVTGSTGFVGTAVVDELLAANHTVVGLTRSDAGVAQLQARPHAKDGSVEAVRGTLEDLDLLRRTAARCDAVLHLAYNHDDFSKYAEATATDRAAIAALASALEGTDKPLVVTSGTGLLTSGDPAGSVVGTEDGEPDAAHPWSVLRGQSERLCKDLADNKDKSKAVRAMVVRLPPTTHGPGSSGFMAVLVATALRKGAAAYVGDGQNAWCACHRDDAARLYRLAMEKGRAGAVYHAVAEEAVPLKDLAAAIGTRLDLPVISIRPDEVQDHFGWFAFAAADKRASSHKTKRELGWNPTGPTVVDNTGVIVDFIKAHGSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V576</accession>
    <name>A0ABR1V576_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Pre-mRNA-splicing factor CWC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_013089</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM CWC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663095.1">
        <property type="nucleotide sequence ID" value="XM_066817403.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050463"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12360">
        <property type="entry name" value="RRM_cwf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034181">
        <property type="entry name" value="Cwc2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032297">
        <property type="entry name" value="Torus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16131">
        <property type="entry name" value="Torus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="16">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="159"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="13">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="327"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="367"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8066342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="396" mass="43892" checksum="E5F82B88367CB9AC" modified="2025-10-08" version="1">MAEDDNDQALVAQSTEVAAPAPKKMKKVVRKKRPARAQVDPDFITSEPPPQTGTIFNIWYNKWSGGDREDKYLSKTPAKGRCNIARDSGYTQADKHPGSYFCLFFARGICPKGQDCEYLHRLPGVHDLFNPNVDCFGRDKFSDYRDDMGGVGSFMRQNRTIYAGRIHVTDDIEEVVARHFAEWGPVERVRVLNTRGVGFITYVNEANAQFAKEAMAHQSLDHNEILNVRWATADPNPMAQAREARRTEEQAAEAIRRALPAEFVAELEGRDPEARKRRKIESSYGLEGYEAPDDIHFARGAQAVNPIGRRGFELEDQQQQLMLEMGGQQQQQDGGYGGGMAALPAPPTRQQEEDGIFSSSTLAALQSAKVAAAPKAKPKASAGPLVAYGSDDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5B8</accession>
    <name>A0ABR1V5B8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663145.1">
        <property type="nucleotide sequence ID" value="XM_066817453.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050513"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="136" mass="14695" checksum="6F2C6A3BF8A5AE3C" modified="2025-10-08" version="1">MRTDNAISNSPDAKNLMVECGRRRDPVAAHDALLSGFSHVVPLQALCSKSSSTLSVTSKPQTAKCANPLESTVTPPPAARRTDLRPVDSMHALEVSAAAAGLAQVSRYRPFLSDRRTRRFPEREAGGLVEKTLLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5X5</accession>
    <name>A0ABR1V5X5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HYD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663367.1">
        <property type="nucleotide sequence ID" value="XM_066817675.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050735"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45763:SF46">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45763">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="45"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="34222" checksum="219A3C9FD26C4922" modified="2025-10-08" version="1">MANNNSTADTTQSITLKDGRTLCYGTNGASGSNSAASAQLPTAFLFHGFPGSHQEGHAIHKAALTHGIRIVSVSRPGYAGSSPEPKRTISSFALDVLELADHLHIQRFAVMGISGGGPYALGCLLKIPADRLAGTMVVSGMYPTSLGLSEMMLSNRVIFNIAPWAPWLIGFLFNSSIGAAAQDVAHPERLKETLQGGFKSMPPEDRRVVEADGGELLDIFTTSMREAFRDGAAGAAYEAALFGNPWDFDLEQLPVRKGELVIYHGGKDIHVPLRMAREAVAKMNGAQLIVEENEGHTLGFCKTDEIMKKLRQMIAKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V687</accession>
    <name>A0ABR1V687_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL27m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_013469</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663475.1">
        <property type="nucleotide sequence ID" value="XM_066817783.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050843"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="258"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="298" mass="33621" checksum="3D4C56A705B9C7F1" modified="2025-10-08" version="1">MSLTQLRRPIVAVACGASSAARSAAATGPLRQLQDVFAQLRIGGPSAKVEGRRYAAVKSQGQYKIRDTSVIPKKLGAKKSGDSYVIPGNIIYKQRGTKWWPGENVGMGRDHTLFAKVTGYVKYYKDPAKHPDRSYIGVVFNKEDKLPYPLHAMRRRKLGMTASAITPPAPEPEISASGIPTTVVRRGEGRKPSPRDERVYKLQESGYSYREENWRLGTLVRTEKRKMGSRRTAMKHRRRRAEELLVEMRKMREDKIARRKEALDAQRAARQKKYREYLARQKAAGKSPETPSPSPQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V691</accession>
    <name>A0ABR1V691_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663451.1">
        <property type="nucleotide sequence ID" value="XM_066817759.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050819"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046105661" description="FAD-binding PCMH-type domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="155"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="648" mass="69215" checksum="7EAE46175299B60A" modified="2025-10-08" version="1">MFSPSVYAFLAAAVALSPLASSQSVLLRGKLSLATSLNIGAAFETVIPGSNRPEAFQLTDAVLANLTSLNLANVTLFRFDDGSPPQTPKCKAFPGESTWPTDETWVTLNVLTGGKLITPVPLGAHLGPNIHDVAPFQGSTCLPQNAGFAGRTCERGGSPVYVVNVTRVADVQLAVNFARNTGVRLVVRNTGHDYVGKSTGAGALSIWTHHLKDIDFIPAYSSPASSYTGPAIKMGAGIVGYELYEAADRFGVSALSGEGRTVGTAGGYTAGGGLSPLTGKYGMAADQVLSIDVVTPDGRFVTADEANHADLFWALRGGGGGTFGVVTSMTVRVHPRMTFSGLTFIVTSGTDPKTAAVSNEVLYAALEAYMRRFPAFAEAGTYAYATLLPSADGTGHTWTMMPWLIPGMELDEYRELVAPLLADWADLNFPVEPDFFTTDSFLEAYNHHFPSDQVGMPTVRTASRLIPRENWANPSVLNDTISTLLDIVAQGSSLIFYCINGGHPPPGAPPSAVQPAWRSAYMFAIVGTIWDAAAPADEVERVNVRISQDWMARLRALTPGGGTYLNEADVMEPQYQEAFYGYDNYQRLLRIKRDLDPRSVFWAPTAVGSEGWYVKDQKSWLTLQTGQLCPVGASGAARGGVGSRVRMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7Y7</accession>
    <name>A0ABR1V7Y7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664059.1">
        <property type="nucleotide sequence ID" value="XM_066818367.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051427"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="422" mass="45645" checksum="1BC3E659A4C1D4EB" modified="2025-10-08" version="1">MLDIIDAPALTMLNLGHWNGPANRISIRRAPKLGPALDRPHNEFASFNASDAFIIELEDAGWVLFPNLTSAGRLEIINSDASFDKLDKVEDLAIANPGDTRAYVRFDTLQNVYGFRLGNASVDIEPLYVAGTDAKRHPNLVVRNSMVIGPWDNDPRRQELLPVNIYHQAMVFPALYRMGGDLNITKNSGIPEMSFSGLTGVKRLYILNNPNSTVPGDFSALEEADLIHINGIMNTTTNPALFPRLSKAAEVKIDAWNPDFDCSRLVHMRNTGIIGYLSCNGTNGTTGEDRSGGPNPSTPRETGLPTPASAGIGVGAGILALGIICVLVWLIMSYRRKLRAATTAGSGGDSKDASDTMKEVSTGTRQEARVESGGRLLPHEAQSREVVESGGTALRAEAEEEHVARHSGYSHRESRGHPVELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9R1</accession>
    <name>A0ABR1V9R1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Epoxide hydrolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013742</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663748.1">
        <property type="nucleotide sequence ID" value="XM_066818056.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051116"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF71">
        <property type="entry name" value="EPOXIDE HYDROLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="4">
        <location>
            <begin position="41"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="466"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="510"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="539"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="598" mass="65907" checksum="4F610C696B97384B" modified="2025-10-08" version="1">MYGTFTETTSIARIMAGDAQPDDAATTAGQNGSAHPPDEEVKPYQLHVSTKYIDLTQQKLEITRLPHEQSKPNSEDWWEPKPLVEPLVDYWLEQYEWRTEEAALNELPQYRSGFTIPNAEAPVRIHFIHARSSHTENALPLLLIPPSHLRPFHLVIPSLPGLGFSDALPNNTAAISTSGEILNSLMHRLDYPHYLVTNAGSASGSPAQIDWKLASYLATNHSDSCVGTHFISPPLAKPRLQETPIAWAKWSLAKFFSAPIMGYHKDDFSALKRNPPAKESKISSLAAQFGMNHQLGVLQEPNTLAYALCDSPTGLLVFVLKYLKLLAPTKEFTPQEIVNFTQLAWLPGPEAAMRFWAHSARHPESPGNPKKTDKVSRPRVAITVFLGDEAEASGFESVQDAEAQFLLPQPEIKESYVCPGWAKTQYKVVHAHRASGKPGLLAWERPELIVSGVRSLAKEILKLDSRLKPNPGPATAPLESVVAGDDGGNVVQADAPLTSNPVLMSPEIGPQPQTPATEAPPLMTALSSDSALLAPIPETEERHQQEREQAQREASEDTRVASDNETAKYPDERKRLLKSKSEETLAERPGQGRMYPVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGR7</accession>
    <name>A0ABR1VGR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664203.1">
        <property type="nucleotide sequence ID" value="XM_066814913.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047973"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="727" mass="82318" checksum="CF06B0F3074E0CD2" modified="2025-10-08" version="1">MAKNQPDGHPRHMRRILPAPVLSKRPPSPPPQQPPPKARAPNVVAACEECRRHKCRRPPPLVLRRKTRLRSLSQAEHPLPLPGDCHPGDPQADQRRPPGSRQRERGDPPAAEEPARPGGPRCLGEAALRHQRLHHRQPGQGRRPPAPAGRRPRDPLSLRVPYRSEMPAEFIVDNPYLNSTLYKAASLYHDNSASSTLPHHVAATSDHGGNPHKPGTAAAEPQSLYLKPFHAAHMVDPRLSDARPSLWTAVCDDDVLMRDILAVWFRCEYQFTSACQKDYFLEDMVAKRHDFCSSLLVNIVLAYACVCYPRFSNRAEYWNPHTLVYRFLAEAKRLWELEAAKPRLTTIQAGMFFNVFHNLCGLDEIGQAYRIHAIDLAHKLGFYDGPITAPSERIRNGRIYTSVWPTAYTYIIHHPDSWASLSCHPPLLKQPPHDPLPDPLKDAQWYGEIWLKYPASQVLSPAYFGYGFKAKCDFRLIMNEFCHAAYSTGSGGSVSLDEANKLRARLLEWYHGLSRPLLPETIVLPAHLQLHMYYHNLILSIYEPLLEVKTTQNPTPQAIVAEASRYMQTLIRLYYLRHGFESMDLFIVIPLVDAGFHCIDDINNKAQKLSPARLEVLRSTLILIAKGLHSQRSNHYLAEALFRVVRGRMRLQEAALLKTSLHFDEGEEERKAGMVQTVRSHWPVSVVKKKEDLDHHILGNLVEEYAHLNVEDGAEGGGRGVFGVVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIH9</accession>
    <name>A0ABR1VIH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein YAE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Protein yae1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_011244</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">May form a complex with LTO1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the YAE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664849.1">
        <property type="nucleotide sequence ID" value="XM_066815559.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048619"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019191">
        <property type="entry name" value="Essential_protein_Yae1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038881">
        <property type="entry name" value="Yae1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829:SF0">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09811">
        <property type="entry name" value="Yae1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Essential protein Yae1 N-terminal" evidence="11">
        <location>
            <begin position="69"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="32"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8071041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="237" mass="25524" checksum="127F53F20E23D909" modified="2025-10-08" version="1">MHVLRRESHSEDLFTAVGSTPEMAYAEDPLDDVFGSDSEPHHDEVAGAEARETHPSDMRRLQTEHSTAGYREGITAAKAQSIQVGFDEGFSLGATIGLKAGQLLGYLEGIAGALRASSNGSGGDPNHSPASALYAKAQTELAAEAIFGEQFWNPDGTWNYEIAPGATGEQHSDSIMFEDVANAHPAITKWTKVVGDLLDQHNIDRAVLDLAEGTPQNSGPVRKEIKVDQQSREVLDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIJ3</accession>
    <name>A0ABR1VIJ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664510.1">
        <property type="nucleotide sequence ID" value="XM_066815220.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048280"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="296" mass="32704" checksum="09782D419B8A9BD5" modified="2025-10-08" version="1">MSRTHVESALEEQTITNALEDLSKVDKVFYDAYAHLRRTIKQSIKAYTTFRIECDDLILQRDALIRDISAIDPEKALHLQDGTDYAVPGVLFEEGDTLLSIKTAPKRLASPEPTLKSDDASGLSVDHPRPNRCHYPRHRGERRTARAVSSASQQRPLPSLPPPPPPPPPPSTRQLRERRKPPEPSSPAIAIAAAAPSAPSLTIKTDHVTKEHYWVFDLPAAAASARGRDRTALYTLRCPAGTCDNPVFSKHPPPPKAGRATLQELRGQVPEHGRPRASVRPLSLLTEFLMYSGIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIR5</accession>
    <name>A0ABR1VIR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664585.1">
        <property type="nucleotide sequence ID" value="XM_066815295.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048355"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="616"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="670"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="726" mass="79623" checksum="76AFFB19FEF9B37A" modified="2025-10-08" version="1">MPSTNEEQGPPVQPWITPVNSGFSDTSATTLIEDDEEPSGQDNDNVTQPNTAKTGSKDDDLETNSTHDTSPRLRLWEQICSGLRLSFRPVDLYNMSCHLWHVVQDYWWLWELATISMSFASMTAVIVILAVENGKSLDDWDFPIQPNSLISVFITLSKSATMTVLTGAIAQSMWIQFEQKATPLMCVEEIQEAGRGPWGSIKLLTAMMKGKRFNLIAIAGAVITVATLALDPFVQQVMSFPSRTIPAKDGKAIFKSTQNWRDLDLTSVQGAILGGVYRNPQITNYTCTESSCSWPTITTLGVCSTCRDLTSKADDKCSTTPGPKTPSQSDLWTFETTNCNYTVGGNITIPMYMQTMSFPAANGQEAEHSSQWTKIKLLPQQGYENYSAKNVLGGMISPDVDYWFTTVLSYSTFFDSRTHPLPKVTPALLAPRIMGCGLHPCGQVWSNPSIVNGTMANGGVPTSSAPLRHLYSNVGLDRFYPTPNRSDWSDVLQVVSKQESAPFPGNGTFTVSQTVANNLTDLMTQTYRATSLAGNENFGDAFPRRRRAAAVAGSGAAGAMTAAKTPVASFARAARRLSEYVRNNDNLDSSGGGDAEAQANWNGKAWRQETYIEVRWAFLTLPLVVLVATLALLCAAILRSREKGARVWKSSSLALLFHDVYVEMAAAASDGPRDKNDKLKGEETEKTTARQCRFQADSVKSMNEKAERANARLAKHDERVSFVVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ46</accession>
    <name>A0ABR1VJ46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664720.1">
        <property type="nucleotide sequence ID" value="XM_066815430.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048490"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="88" mass="10443" checksum="1C5CD0D22F00CDCD" modified="2025-10-08" version="1">MHCYCANYYSAVNCHNKVSQFGERCRLCTVMNEGVSARYDSFNHQAQAQSYQPQSYQDMLRDDSSREERRGRQRERKGKDSRKSRQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJI4</accession>
    <name>A0ABR1VJI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664855.1">
        <property type="nucleotide sequence ID" value="XM_066815565.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048625"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045559218" evidence="1">
        <location>
            <begin position="32"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="97" mass="10633" checksum="AA6E79CCCAC3B956" modified="2025-10-08" version="1">MTDVPWSLTLQCSGVWLHLLSGSVHVPGTKAIPVRYGDQQPAMAMHAGYYLARLMFAAPVSTANQKSTQSALDGFIIELDHDLERGIFDANGQLFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT83</accession>
    <name>A0ABR1VT83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta xylanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665378.1">
        <property type="nucleotide sequence ID" value="XM_066813416.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046476"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33428:SF14">
        <property type="entry name" value="CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33428">
        <property type="entry name" value="CHLOROPHYLLASE-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047207374" evidence="2">
        <location>
            <begin position="18"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="271" mass="28547" checksum="AB5C5C25691682F7" modified="2025-10-08" version="1">MKFNAIAISALAGVASASPVDTRQNGGGDGPFGPGTYKTESSLQQHTIYMPSKTTGSTKMPVLVWGNGACSADGRSNVQLLQQIASYGYPAISSGGPGQQGSTTAKMMTDSIDWAVANAGKGAYANVDATKIMAAGFSCGGVEAMAQIWDSRVSTIGVISSGLLDNQTAATHFNKPVLFCPGWAERYRLRQRREGLQEPPGQHPSWKGNINVGHGGTLGDQNGGKFGKAILNWAQYVLRADDKGKAYLTDGYKADGWAVETHAFDQLKPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTT7</accession>
    <name>A0ABR1VTT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665517.1">
        <property type="nucleotide sequence ID" value="XM_066813555.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046615"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="251" mass="29220" checksum="11A2164D597AA549" modified="2025-10-08" version="1">MSTSTPPGGSSELSEPANWKGLMGDTCREMHRTGFEEWGFVIYRCAYGNDEAWDRYMKYFRAAIHEKLVSYKCEFMEQYARWIVVEDEMDLRAASKLRVRQRFVNWRDQNTVWRTAPELSKYIPRMPYEATLRLPRFTYCLHVDQDCLDTVDAQAAAKPTETYSDPAPMLVVALIDGDFVDHSSIDDYKCPPVEGCTEEYVGWQYMPVDLLPCFYNDHHYYTLESDVNIEYSRPPKISPFCIGSMPLGKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUS0</accession>
    <name>A0ABR1VUS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665938.1">
        <property type="nucleotide sequence ID" value="XM_066813976.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047036"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="115" mass="12321" checksum="F7ECAD8C4A52CC40" modified="2025-10-08" version="1">MASESQKEAWFLKYSFPVTFPSHPALTLSEADFGDFLERDLSQDASTHVAPTEPADKKETESDSLTLLTPPSTTAELRGATEVLNLNDSPAKATKAKPEGDEGAHAALYEGPLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVY2</accession>
    <name>A0ABR1VVY2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666297.1">
        <property type="nucleotide sequence ID" value="XM_066814335.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047395"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="546"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="650"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="724" mass="80517" checksum="F8AE5DA9AA4B99CB" modified="2025-10-08" version="1">MDADAQVHLGIWTNWSRGSAVKGATLTTTREQGNLLIAFTALFVPFVASRFWRIFAIIFHQCYSTSDMRDAIHHQRQVALRNSSSPESGLMTLIRLMWAWRRTARRSWIRVLPVTMFSVFSIGAFTVAGGFSSQISTSDEVLLRGDDCEAPTAITNGNLTLSSAETSYWASLENTVNNYAQQCYSNQSSGLLECSKFVVRTVPTAVMDYNAPCPFRSGICRRNSSNLLLDTGHLNSNDIFGLNARRDETFTMRYVLKCAPLVTESYTQAVTAFNRTFTVYNYGPGLSTADSKPNYTIAVPDIESQARNFLTFQGAFVETSSTFRPDPAVVEPDGDVSLFFLSGNGVHFVSKAEDDWYRATVRAGTLSNFDGPEAHDTYRPEEAASPLGCIEQFQWCRDPDQGQCGKLEGSLDSQISATPWFNISREDLEPDRPVSQTRLGSAIIWAWYALSIDSGDNLSTTINRIGAATLASQESISQGLMWTINEKQWQLDVTRWWHIMLASFQAKFVNTAQGSKDSPFRPYTIPPANDYERERCSNQKIRSTKYANFSILGLVLTYSLGAIIVIISFIIVPVLRLLQKHGWYDKYAYLEWEGDTAIQLHRVAQDQLGHGHWTDCDERIPITRPDDLLAPLDISDPKHPMLARIVDNTTSEEPKPETTSQHSASEQTSLESSVEHIDNGSAGGTSVGVRRAFSDAHSGALGGKRFHGLDADLERCQTRPGTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW20</accession>
    <name>A0ABR1VW20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666384.1">
        <property type="nucleotide sequence ID" value="XM_066814422.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047482"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="67"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="265" mass="28876" checksum="851A1D521932B29F" modified="2025-10-08" version="1">MPVSPPPGLEIRPARASDMTSIVDLLDSAPDDAALYQFPDLSDHPEALRPMHRAWVRGLLQDPTSLTRIAVLDGNAVVGFSSWVRRAPNPDDPDSLHRMKISEPLILDEEEGPDGSEALPSIEPDKTRAEAIARVRERLSRTSPFQSVPRYSLQGLAVHPSYQSHGIGRLLVRWGLEQGIAEGVPVLTAGETRGVKFYTGKALGFQIVKGSVWWLDRDGQDISEQEFKSGGNGGWESMYGGVSGAQVVWFPPGLSLEIGGVIYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWL2</accession>
    <name>A0ABR1VWL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666586.1">
        <property type="nucleotide sequence ID" value="XM_066814624.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047684"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="346" mass="36379" checksum="42C492B7334D9E8C" modified="2025-10-08" version="1">MPLLARPSSGMIWWPVTTLKRGYNGTNSANRAGYQQGGVSVKVTAQEDDGVAFSYSSPTTTDGFHVSVSAPAPTPSTSTSSLPSLHATITPTKEPDAISSHSLPRTTTPSGLGILAEAAAAVTTPETLPSSATAQLSAVPLLSTTLEPTHATPTDNPMNLPSTDRGNGLSPDEITIIVAVVISFSVFLLLLATAIRCAILQRRKHEARERARRIQARNPMSRLPPALKKPPESSLHGASTARGGGHLTEDEPNLEDDNTEFRIVIRPPPGYQTPQSGATTPIDSHHYPPGSRPPSARAFGMPAAGCATPNEGGHHWSLDTENGSVLSGSTRKINLNRLSITTTESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX51</accession>
    <name>A0ABR1VX51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666717.1">
        <property type="nucleotide sequence ID" value="XM_066814755.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047815"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="47"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="482" mass="55154" checksum="EC9E16577C644E99" modified="2025-10-08" version="1">MDLNTYPYTPLHGDEIRYLVIHAFDESIGVVQCSLYHAPFHGLDNSFTALSYVWGDVNITGTIQLTEQPFSVTTNLRDCLRQFAMNPKYQERKLWVDAVCINQQDKNERNAQVQRMVEIYSNAESVIAWLGPGTHLSHVGMQRLQNVSLDEVKVMGPSTEHDVVQRRKAIWSELLEGYGEQGLQDLVLRPYWHRTWIIQEIALGRRTRLVCGDDEVAFENLKAVQWLIMCSLPFHIISTFRKEHQQSINRLSIDSHTASNIAFVDNAQGQLLDCVSKFAAFQCSDDKDKVYALLGLCRDAHHIVPDYNRPTAKVYGDVVEAHIKAHDNLYILNHVEYNSEKDRSCASWVPEWNRSTANPFRALLNDPEHVFQASRRLPLSDRPWSLDRDTESLHLTGACLDTISTLSTVLDVNDLTGNEVIVTALKCLHWIYQALLQSPFKRRITSGDEDCLHLVYQTFEHGPMEYEDTSTHAEWSGCHDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXH0</accession>
    <name>A0ABR1VXH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Virulence sensor protein bvgS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009699</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665976.1">
        <property type="nucleotide sequence ID" value="XM_066814014.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047074"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058846">
        <property type="entry name" value="PAS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF30">
        <property type="entry name" value="TWO-COMPONENT SYSTEM RESPONSE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26131">
        <property type="entry name" value="PAS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="294"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="465"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="796"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="432"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="940" mass="105232" checksum="783E0630311942C9" modified="2025-10-08" version="1">MMAQTETRLDSTIVEVLANDIRPTFIVEIAESASAPQQPEEHPQLNIVHVNPALESKPGLHDEVQRVTTSGHGRFLAWIGGNDTLDGDTKSKTFMHHDICWSRTPFRQKWVIVGCNKQVAHNKALVKEQIAVKTKEANESIAKFQSIAEFIPNGACFGDREGNITFANDAWYRIIGVPKSTPLESQIFMDRILEEDRHNLTRAWSEMRHSGTVSIEFRVRGDSDYPLHPPIGSSPSLEKAGLDFTAEKPKTRYISAALKGELSPDGTVVRVLACLTDVTLYKLALEEALRHAQQHQNFKEMAESATVGMYELNMAGHLQWANTAFYRMCGLEKADTVNGTLKPFESCVVEEDLPLIQQSLDRLVAGGRHEQRAEIRLKKTWTEKDSSGNEIIAPRWASATFMPVKNSEDTIQTFTGCLVDMSLHNWRIESERQHKEEAIRRQQEAIRRQEEAIESKRQQENFIDMTSHELRNPLSAIIQCGDSILASQTQVSELLNNLRSELPKTVVTRTVSDSISRASNLVQNTIESAETVLSCTQHQSRIVDDILTMSKMDSNLLSVTPTTVNPILIVKEAFNMFRVEARSVDINLTMTVDPSYTDLNIEFLDLDPSRLKQVLINLLTNALKFTKNQAQKEVSIRMSASKSRPRDGTSSVQFIPRTLEEPQQPQRVQTGVDSTFLMFEVKDSGQGLNDAEKKSLFQRFVQASPKTHVKYGGSGLGLFISKRLTEMQNGAIGVASEPGHGSTFAFYIEAHVPSDAAAQEARETNRNLEKILKTPTGTPTIANHDGTTAEDKLIHGVLIVEDNLVNQKITQRALKERGYNVQVANHGLEALELLEKTDRRGGDFPLSVIMMDMEMPIKDGLSCTRDIREMELEGKLKSPRIPIIAVSANARMEQIEEAKAAGCDDVLVKPYRIPELITTMEKTVRRLNMNKKEKGEGTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZ24</accession>
    <name>A0ABR1VZ24_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666531.1">
        <property type="nucleotide sequence ID" value="XM_066814569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047629"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="157" mass="17721" checksum="815F5BCF1DA90CD1" modified="2025-10-08" version="1">MAYQSRFFATDHILIATLTCILDHDTCKAILSETADDKIQDCIDEGNSTTQLLNDAWEAKHETEPDEPIWMWYSIVYYKIEEIVKKQRPTALSPIARPFVPASTIPSPSPAGKSNEKVKIESAAVPERNGEEEDLVMQNFMKRCESGNVRVSKSEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZD9</accession>
    <name>A0ABR1VZD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010193</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666470.1">
        <property type="nucleotide sequence ID" value="XM_066814508.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047568"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF37">
        <property type="entry name" value="AMIDASE C869.01-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046107629" description="Amidase domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="113"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="613" mass="67404" checksum="C2A60E9A6A557C20" modified="2025-10-08" version="1">MRLFSAGIAGFAALAGASSATSGDLFPMPKCKGIEIQNLPIDSLQKLMTEGSLTSRDLVQCYLARIEQTNRYICHRRFELSKSQSLTLYQLHPLHKRNQPRRPRHRHRPRHRAPRRPPPHPLHGIPFLVKDNFYTADAHNTSEGTLVLLGGRSTAGESTIVARLRAAGGVLLGHATMSEAADHRALTSYASGYSSRTGQTRNPYNLTQSTAGSSSGSVVAVRINQAAVAVGTETYGSLVHPAAQLGLYTVKATPGLLSRRGVVTGSYYHDTPGPLARSVRDVAVMLDIMRGPDPLDNLTFQAVGKYPVDGYTVHLTNRSALRGMKFGIPWDPYWSTNAHMNSPGIRQVYEQRIEELEEAGAQIYNITVKQPLHRPRQRIRRRPTHHHPPPYQHSIAFATLLAAGYADWLRHWTFPKDDPRHGTLKTVADMAAWNAAHNASTGALGNNTWWQDETTGQSFYDAAAATNGSLNSAFWTAFGWSRTTARQAIDQAHVYLTESGTRMIELDGVLVPNGRAGGYSSACAPMASYAGYPIASVPVGQDGFATPFALGIYGRQYGEAKLVQVASAMEDLFKWNEAPRWHNADVRQDRPWDAPWPGYTCSKESLARQACTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W097</accession>
    <name>A0ABR1W097_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010267</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666544.1">
        <property type="nucleotide sequence ID" value="XM_066814582.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047642"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF124">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="53"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="311"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="381"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="435" mass="47707" checksum="3937DF7910D3F39D" modified="2025-10-08" version="1">MSTGIDTSGRGMAYMTEPPPGEQRYLSDWPSIAYQVQVSGVVTTVIALITVVLRIFTRVHLVRSGLGLDDLLVVLAAFTTCAFLGITFQMCGIAIGRHFWQVTVADYSPYFLAYSTAATMTYSLSVIFSKLSILFLYLRLSPQRSFRFAVITLIVIVSAYALAYQVVSIFSCKPMKAAWDITITDATCVDKEAVYMGLSISNIIMDVIILLIPIHVVYPLQMSKRQKVSLVMLFATGGLYEQNSVCASAIKRTVILPPLMHSPDYSWDVAEQFVWSYIEVNAGIICATVPALKPFFVRYLPELLGASLGSSYGRKSSEPPSLPLSTVVEQNKKRRGTGTKLSSDPYATIEERYLDEDEQKLWTREAAAGFGNREKMGLDTVVSSPRYPGGADSSSVDSNTDGSGKGHRAHGRSFGSAHGISVTHETRVDYTGRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W0Y0</accession>
    <name>A0ABR1W0Y0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666708.1">
        <property type="nucleotide sequence ID" value="XM_066814746.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047806"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="76" mass="8566" checksum="29A017A23980CCED" modified="2025-10-08" version="1">MCTVDVHLYLCGNCFKLVGRIQNEATFVACDHKDNYMPGCPNYVPNITTHSEGDLCGGCARRIQEEQAREEEANRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8A0</accession>
    <name>A0ABR1W8A0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667184.1">
        <property type="nucleotide sequence ID" value="XM_066811842.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044902"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="51"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="351" mass="39620" checksum="590FC5E056963508" modified="2025-10-08" version="1">MPKSTAAPLPKMESSNHDKGESAIVSFVGGREFKVAAKAQNTPASPRLDQFTCFLKLVQELRDMIWRFSIPERALLVGPWAELDEPNRPWCHKFFEYAPCTSQAARNHLSLPAVAQSCREARKAYLRFVRDEAAWFRPVHYTLRPNPGRSRRVHRQEDDGQDAVAAAGDVHGVRQDDLRPPPTWSGPAPGTLSVESPVALVNVRDVERIRQFKEVYEGCSAPSHLDPKVVKHLSSLLTTESRERYLDLMRLNVISLWAEILFPDLHTGGTGANQFLLTDPGTWRRCLHAFTPYNLRQHWVRDVIIPLVPQVQMVVAFKLCDAACHVGTNETLGKAKDDCERCRGRSVCLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W969</accession>
    <name>A0ABR1W969_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="2">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007873</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>precorrin-2 + NAD(+) = sirohydrochlorin + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667530.1">
        <property type="nucleotide sequence ID" value="XM_066812188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045248"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3280.10">
        <property type="entry name" value="Siroheme synthase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028161">
        <property type="entry name" value="Met8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028162">
        <property type="entry name" value="Met8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330">
        <property type="entry name" value="SIROHEME BIOSYNTHESIS PROTEIN MET8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330:SF1">
        <property type="entry name" value="SIROHEME BIOSYNTHESIS PROTEIN MET8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13241">
        <property type="entry name" value="NAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14823">
        <property type="entry name" value="Sirohm_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75615">
        <property type="entry name" value="Siroheme synthase middle domains-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Siroheme biosynthesis protein Met8 C-terminal" evidence="7">
        <location>
            <begin position="149"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="247" mass="27159" checksum="4864DD379277ECE3" modified="2025-10-08" version="1">MTESKEKFPEVQGGGSLILAWQIKNKPVLVVGGGEVAAGRILNLLNADAIVTVICPAEGLNPEVRHRIAHNQVTHIDRNACRRPSTPDSPLGPPAMVLTAVDDPAASTQIWKLCQAARIPANIADVPPECDFYFGSVHRDGPLQIMTLPVGVGDAIERIGLLRARLRELSPEIEEGPKRMRWMIRVSDRYSWDEMCDLSDEDMDNLLSYYKPNKVPDIDILKAMRGGTMSPEDIDVFDGSFGFSLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9J5</accession>
    <name>A0ABR1W9J5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008008</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667665.1">
        <property type="nucleotide sequence ID" value="XM_066812323.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045383"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF311">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G10180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12278" checksum="6EA117CF88323401" modified="2025-10-08" version="1">MDSSKCRTLHIAIVGAGIGGLICAIACRRMNKNLKATVFERAAEVLPLGAGIHIPPNAGRVLAYLDLLDKVKEEAGGYQLDHFTLRRYEDGQILAAKPVKERVGREYGAEWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAD8</accession>
    <name>A0ABR1WAD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667857.1">
        <property type="nucleotide sequence ID" value="XM_066812515.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045575"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451">
        <property type="entry name" value="MARVEL DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF4">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="22170" checksum="8CE9689577889075" modified="2025-10-08" version="1">MALSGLTAPGVPPQPKWLLFIKGAIVLLAAVILALAAYAASLYGDLSYYYSAGAPGYLLFVAIFSWIVYGAAIFLELKAHHFYYRIAMLVAYILTCIFWLSAWAWAASWASFVLAYYANDFYYPGLHTFGSVMAACAALGAVTWVLCIINLVFFIIGSVLNHDATAPSNVELGHGPKPAEGVQAQTPAYAQHQTAQPTPVQPQQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAI2</accession>
    <name>A0ABR1WAI2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666996.1">
        <property type="nucleotide sequence ID" value="XM_066811654.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044714"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053029">
        <property type="entry name" value="RNA_pol_I-specific_init_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007224">
        <property type="entry name" value="TIF_Rrn11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244:SF1">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04090">
        <property type="entry name" value="Rrn11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="566" mass="63157" checksum="BB1EBF896B86BAA4" modified="2025-10-08" version="1">MGGPFAFPVPAYRLGDHKSRRSKRKRADDAGEDGLNASTGGGGGGGGSSRGPEEFTSTPFGTQASSFSSLPANSINPLSHSPDTLRQFAVAGLDPEEEAPSKVYPKFPHKGISSRNAFSAKRGGNRKKGSGRMSALTSGSEADVDTDASDSRGGKDLGGRGEEDEDGFQMNYSARMRHLNTLTAIMHRCLHDGDIPRAKRAFNLLIRTKDVDIRVNGLWNIGVEILMREGEQSQQKQTSNTTANAAAVSDKGKEPEDKWNLGQPLADDDDPVSQLQDKQATSVEDQEEVGSSGDPRTSPLQLPDRWGSAANVDTVKEYLQALIQQYPYDQHRPHMVSALDFWPTLFSIEIYNLDAEFKKAMRQLEVKEDKDEDDDDDGEARESSSENEESYHRSDDDEDEEDQESRRLRRREDARQARRHRVRDDVRASTRAAAEQVAARMDQQMENRPYGTHGELLRLRGMLSLYVADLHLCASLVAKVEEHMRRKRREGSGSRSGSKPRKGSKSLGKHAETEEERAKSRLRDAEIEKARRFFRKMLERDGGDVEDWVRRFAEGEEGDEDEEDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAN7</accession>
    <name>A0ABR1WAN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component SEC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008305</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the exocyst complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SEC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667962.1">
        <property type="nucleotide sequence ID" value="XM_066812620.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045680"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029175">
        <property type="entry name" value="EXOC2/Sec5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039481">
        <property type="entry name" value="EXOC2/Sec5_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15469">
        <property type="entry name" value="Sec5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC2/Sec5 N-terminal" evidence="6">
        <location>
            <begin position="86"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="20"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1010" mass="112603" checksum="2CE4770060FFE036" modified="2025-10-08" version="1">MAAPDFERNVLEFYGVPTAFPAEWPTDKDNSDASDSEAEQKKQKHNRRKSRYQALERAVSDRRTSIVPGSEVSSGGVGSLVQRDEPDPLGGSDSVVGSLRRFGFPVQDDPRLRTKFLLSSTNFSPSLFLSQLHALDDTRMLESGLDSLSQSIDLKSASLKVLVESNFERFVKAKATIDNVYKEMKYRGAEPPSPTRARAHSRHASRSSFRNSIGGPAFGANPLVSPLSPESDYGVMGIKTPLLDVSAKAEDVWGPALGGREKEENLKTVQYSIERFRDYIEASSNVADSIKRRDYETLVEEYTRARRFADDARRLVQDLGTTAPSESQAYQILLAARMWYDVDDQIQTFKRDIWKKLISLNGVSKTEVQAGRPQDQHMELISLLLELGVEDNPIWVWLLSRFDYLKGKISSVADRGKVEIEVLRRRLANGQKPAPQSVAGHLRALGRQSVESKPDGIDAPDVIELWEKMLQFLNMLLSTQGILGEILEFWQTVDGFIEGKTQSSLPVGYNGESREHHRLSDQGTLDLRKGTVELVDMIRQHVLEFFAGAPPEDISLLFSPLPQSPGTPVSGSLTPTALRDPRFNFDSNNLPPPSPRRGEAWEKFAFWPPNANSVSGVHYLSKMLAFVGSGASEMASITPVTQIDEKQVEHLKTLVGAARERCVTAICAAWNKDAENIKYVEDWQRSRELGDVTRMPTTFAAFEGALLGGMQKILYISEAMTKPDTADIVLPPPTKLLQMVRSQYVTTLYKALSGMVENAERSIKKADDEWTTDLDTPIHSGSARTSLSVGMKGIDAGDRNVRMLLTLSNLQALRSQVVPNLNGQFENSFSVKLTDESKTIKDVLGQIDARLFQTYTKPSIENLRRIIHSGLSDDPSWGSSPKPTEVKPYIYEALLSLVLSYLLEQLSRELLEAFKARSPRYDLGALMQATLDVEFVAQTLSQYTTERASGLQSEIYSMLDSRTDDAARARLQGELPGMRDVLKKLRDLSKNSFACFKKPRKSQVERTMTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAP2</accession>
    <name>A0ABR1WAP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667582.1">
        <property type="nucleotide sequence ID" value="XM_066812240.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045300"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039632">
        <property type="entry name" value="TMEM42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="31224" checksum="C2D500813FBA7CCD" modified="2025-10-08" version="1">MAPRKKPARQEPARMNPDESNSGLPSSTSVSTAATSTARRRQAAAASSNQKMSNDDGGIAAASRSSTESVRDPPSTTAAPPSTSWATRNQWIVLAVASGACAAFNGVFAKLTTNNLTTHIAEVVSGLLGISDMEQPIEYVVRAMWTLFTKALARGSSTTQVSIMNTSSNFVITAVLGFAIFSEALPPLWWLGAALLVAGNVIIGRKDEGATAGDEDASTASATEESSSEQPLLGQQHQQSRYDGGAENETLAAGIAASIAASGVAAVAAVAAAAQVDESLPKIEKDEEDEDVAIIGDVASDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAV8</accession>
    <name>A0ABR1WAV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sec63 Brl domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008458</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668115.1">
        <property type="nucleotide sequence ID" value="XM_066812773.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045833"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18020">
        <property type="entry name" value="DEXHc_ASCC3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF13">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039073">
        <property type="entry name" value="BRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="288"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="512"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="1140"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="1347"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1895"/>
            <end position="1919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1953"/>
            <end position="1973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1900"/>
            <end position="1909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1973" mass="221459" checksum="EA182F6706859325" modified="2025-10-08" version="1">MAPHNSTSEAESQWRAQFEAMKLALAELKLPNASSNSYKGSVDDFDLDDEDFTSGNSGDDVWDFISDSEEDLYSSDFFDDAVDHDGDSSPGPSWFTEQCAAVAARKNGLSADAFEAQILEVLSSGQSADEVQSHLTDLVGFDDLDFVIEILSKKDEIVSSYVSRETAQPSGNRLLTKAEREDALRRKDFEHKNATLAPTMHKEVQYPHVYRSHTAGNTLSHSGNKYALPAGSERKMFEKYEEYMIPAGKTGTLAPGRRLLPVAEMDGLCRRTFKGYKALNRMQSLVYPVAYKTSENMLICAPTGAGKTDAAMLTILQTISQYVTPNPIENNEATDFAVDADEFKIVYVAPMKALAAEITEKLGKRLAWLGIRAREYTGDMHLTKSEIVQTQIIVTTPEKWDVITRKGTGDTELVQKVRLLIIDEVHMLHDERGAVIESLVARTERQVESTQSLIRIVGLSATLPNFIDVADFLKVNRHAGLFYFDASFRPVPLEQHFIGVKGKAGSKQSKENLDNVAFEKVREMLQQDHQVMVFVHSRRDTMQTAKMLHEKAIDDICVDLFDPQSHPKYEQAVRDMKSSRARELRDLLPKGLGIHHAGMTRSDRNLMERLFGEGVIKVLCCTATLAWGVNLPAAAVVIKGTQVYSAQDGKFVDLGILDVLQIFGRAGRPQFEDVGIGMICTTLDRLPHYLSAVTEQQPIESRFSSKLVDNLNAEIALGTVTSIPEAVQWIGYSYLFVRMQRNPMTYGIEWAEIRDDPNLVQRRRQLAIQAARTLQKSQMVIFNEITEELRSKDIGRIASQFYIQQTSVEVFNMMMKPHATEADILKMISMSGEFDNIQSRDSEEKELTHFRREVVPCDVEGGIDTPQAKTNILLQAYICRAQPEDFALSNDLNYVAQQSGRICRSLFMMALNRRWGHQCLVLLTLAKSIERRIWPFQHPLHQFDLPKSVLNQLDAKESLTVEAMRDMEPAEIGGLVHNHSAGKKIASILDNFPTVSIDAEIAPLNRDVLRIKLFITPDFRWNDRVHGTSESFYIWVENSETSEIYHHEFFILNRRKLYDDHELNFTIPLSDPLPTQIYVKAVSDKWLGAETVAPISFQHLIRPDTESVYTDLLNLQPLPVSALKDMRLEELYSKRLRSSIPSTIPPANVLLGSPTGSGKTTAAELAMWWAFREKPGSKVVYIAPMKALVRERVKDWGERLARPLGLKLVELTGDNTPDTRTIKDADIIVTTPEKWDGISRSWQTRGYVRQVSLVIIDEIHLLAGDRGPILEIIVSRMNYIAESTKNSVRLLGMSTACANASDLGNWLGVKEGLFNFRHSVRPVPLELYIDGFPEVRGFCPLMQSMNRPTFLAVKTHSPDKPVIVFVPSRRQTRLTAKDLINLCGMEDNPRRFLHMDEEDLQLNLSRVKDEALKEAISFGIGLHHAGLVETDRQLSEELFLNNKIQILVATSTLAWGVNLPAHLVVVKGTQFYDAKMEGYKDMDLTDVLQMLGRAGRPQFDNSGVARIFTKDAKKDFYKHFLHTGFPVESSLHTVLDNHLCAEVSAETIVTKQDALDYLTWTFFFRRLHKNPSYYGLEVSAEEHNTIAAQQMANDFMIEMVNNSLDQLAESKCVEVFPNGDVDPTPLGKIMSYYYLSHKTIRHLVKHAKPKATFAQALQWMSSATEYDELPVRHNEDLINAELSRNLPFSANDFGLPLWDPHVKAFLLLQAHMARIDLPITDYVGDQTSVLDQAIRIIQASIDVLTELGYLSSCLEMIKVLQCIKSARWPQDHPLAILPGLNVNELKDTTSLKKLGTFTRPQTEELAKKLHVPSSQLGRFMRAASILPNINVKPENVTAQSLTVSLKRTNPIVEREGRVYAPRYPKPQTEGWFVIICNAASDEIIAVKRAGWNQGPGKSVGTGTKPSANVTLKLPEPERDGKGRKVDVIVLSDAYIGLEYRVMGVDIPALPVVDDDVDKSKKGGDVAAGGASKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB80</accession>
    <name>A0ABR1WB80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiamine pyrophosphokinase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668231.1">
        <property type="nucleotide sequence ID" value="XM_066812889.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045949"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03676">
        <property type="entry name" value="NUDIX_Tnr3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031804">
        <property type="entry name" value="DUF4743"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622:SF8">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15916">
        <property type="entry name" value="DUF4743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="84"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="272" mass="30798" checksum="70C26E44AD81E918" modified="2025-10-08" version="1">MYDAPARILRAFEQPTEPERSAAVAAVMQRWREQKTFELLSGWRDELWPVYTTNDPKAPELLYNVERAGAGLLGVMRYGVHMTGYVRSSSTTDGDDNDNNNNLKIWVPRRAADKSTYPGMLDNTVAGGLMTGEEPFECMVREADEEASLPEALMREKCKLTGTVTYIYITDERAGGEKGLIYPETQWVYDLELPADVVPTPKDGEVAEFHLWTVAEVQEALARGEFKPNCALILLDFFVRMGILTKENETHYDEIVRRPHREVPFPGPHQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBE7</accession>
    <name>A0ABR1WBE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhamnogalacturonase A/B/Epimerase-like pectate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008654</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668311.1">
        <property type="nucleotide sequence ID" value="XM_066812969.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046029"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039279">
        <property type="entry name" value="QRT3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928:SF2">
        <property type="entry name" value="PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928">
        <property type="entry name" value="POLYGALACTURONASE QRT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045869989" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase domain-containing protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="3">
        <location>
            <begin position="526"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1296"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1367"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1303"/>
            <end position="1322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1493" mass="164882" checksum="B074E59CF3400F50" modified="2025-10-08" version="1">MASVRHLLYLFSVLIIPLLCPQLRNQVLGQFIQGYVQRDLATQRPTYWRPTTNDAFRKVVDLSPETVILVYNCWYMTDIGQNVENWRNTPRGQAQFPQYLFGYDLNTGKKGRAKPMRHDKEWYYSHLEPGTQVNGIANKRNALGRVTEYAKIRYTCDEYPPATWVEGGSGSLSPEAAPANAATRCAAMKCAKNVKAEQDWQGESHERLRNQLLYLARRQGIQFDPTQSVILFEHVIDTHPHNGVAASIHSYFYPGKSQSQPGEDKIVTQAKRAQDAGNGTYSHLGYGNLSLEEFLASVNATSHHIFVNDTISDIPSLDIPGGMGTDIDAALRYRSELQDTQWVDEDESEDDYDAADLNITRFRAPRLWQELRKPDTITVSEPKQHEVRGTVSGTRTPLLKNATSFSLAQARRIVEEAKARSATLNRNRLANPRRNNYGLKPGTNLRGEAKQRRSALKALRVASDMPLLSIDDTIAAAAALVAEAEATDFVGNGTRFPANMTRQNHRKRAKTGSYWMAQLDRKGTIFRNVLDYGAVGDGITDDTKAISRAMNETRRCGEKCNGSTTKNAIVYFPPGNYLISSTVPMPFGTQVIGDAKDWPVLTASRSFVGLGVLSSDEYTGGQEGAEQWYINTANFYRQVRNLRIDISRASPDQDVAGIHWQVAQATSNQNFEIIAAAGSTTQTGIFAENGSGGVISDITFRGGKVGLYGGEQQFTAQRMTFDGCTTGVQIIWDWGWVWKSITMTNVDVGFRLMAGEGETGIIGSAAFYDSSFRSVGTAVLIAPPNPAPGSGSTGVIVENVEFQGCRQGGWRHQRRHVAGPDGQGRPLGPCLLDSRGRYFERAKPQYEDRAVGDFVHVKDFGAKGDGVTVDTAAFHNPQALVKVGNIGDVGDVEMQDLIFTTRGPTAGAVMVQWNIRAASLGSAALWDCHVRIGGATGTNLGSDECPALTSGMPQGCNAGSLMMHLTSTASGYFENMWLWVADHMIDDPALDDAANDMAMTSIYVAHGFLIESTEPVWLYGTASEHATFYQYNFNNARNVFAGLLQTESPYYQPTPQPPAPFQDVVGVFPGDPAYSCAADNEFNGCDQSWAVIVHGLANIFVAGAGLYTWFSTYTQSCIDEHTCQKALLLLSENYNNVWFQNLVTIGAKYMAVMEGQGISALDNLNVNSHPSWSQISVLDVRGNGKTFHELHWLDPKIWDMERPAFTCSPPCRVKIPPWTGATSTVNYPVMTISTGSFSTHIFAPPLTISEWIFEEVTVGMRSNGMRRRQDLTEFWPVPATTSAWPAVTYIGPAGTAESTRPDMPFPTPPPSIEPGAAPPPKGRWPTRAIQPSRGRAPKGWQGFGELNPMDEDPYDEWGPDVLVMCPEEDETSSETAPAAPTKTPISPPVAVPSPMEVGHTLKNRPPCYNQGKATTHERMDNAIRSFCKYLGSPVSIFGKRDGTEAMEDSVRVFRDDFHQRKTEPFNDLNILFEFEVFAGCEWKYNFDECRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCB8</accession>
    <name>A0ABR1WCB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008978</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668635.1">
        <property type="nucleotide sequence ID" value="XM_066813293.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046353"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="637"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8081160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="737" mass="80963" checksum="6C61547C7F433413" modified="2025-10-08" version="1">MEYHNVPLQDSPPLATGAVTSPPANQDHSRSTSVSPSPTQSATGSENYQNPTQGQVKSHKRNTSSRIFTFDHFKGKNGPKVETRGLLSEEYKEGKRRYNWRSEILLGSLAVASALAIILLFVFSDGHPLDSFKIPMGLVIAALGAITRGALAFAIGACLAQEKWNWLRRKPDSLASFQKFDEASRGPMGSIQLLYWLNIRHWATVGALVTVLLLGFDPLLQGAISYEGHLVDSQDLLPPTIPYGGRLNAGSYAPNPSSGVHGVTGKDNMTFPFEDYSSIPDLKMASAIYDGFTDAPSAVDFHCVSGNCTFPPFLSLGVCSSCNDVTRFLNRTKEATTQGTVPSPSTIMLTDNYTKYSLGYVKLSNADTLHEHSLSAYMVVGATSSPAKSVSFKDNDRLIAALGVIEAADTYEKHETWWNETAVRATECALYFCIKRFDALVTKSDLKETETPIGTKRVQDSYGPARAGDRQKFEVMREKIGGGLMFNDGNGDLPREDLRLEPDPAGDEDRRHLNDTDLVAPATFNVSQSAVGSMISFIWKELFLGDSGTGLPLIWPPYQANQGFFQSSVSQAFHDSRDLSATMQRLATGMTNWARDASSSDADNATTTMTAQEQQQHPQGQMLGTQQTWTLHIKIRWPYTSLPFATLLAGFAFVFLSIRETRKLNMVPWKGDVIATMTHALDAEARDQLRSAAREGQVRQTSKTLVLNFAESNQGLELRAHQGEQGQQQVKAKTFPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDN5</accession>
    <name>A0ABR1WDN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668602.1">
        <property type="nucleotide sequence ID" value="XM_066813260.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046320"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="96" mass="9597" checksum="FBD70D1D5F2A5937" modified="2025-10-08" version="1">MARRIRRAAAPAARRGAPIRGAHAAPSPRQVGDGAAPPKSPMNCAASQAATQPQGYAARGPSGTGRAASRRRAGRTGAGCPPPFGGSRRSTVSVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEL6</accession>
    <name>A0ABR1WEL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008764</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668421.1">
        <property type="nucleotide sequence ID" value="XM_066813079.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046139"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="55027" checksum="106D646A2CFEF348" modified="2025-10-08" version="1" fragment="single">AVSKLFFLHTMAFLALTTVLVGLGTIIISVALWRRFFSPLSSVPGPPLASVTRFWHVRHVIKGDQNRELIRAHEKYGHFVRIAPGEVSVSHPDGPKKILLATLHKADWYKVATFPDGRYMNPFAATDPKLKNELSKHVAPAYTLSNVLQSEEAIDNTIALLLGWLDRFATTGEPARLDEFVSFTTSDVVGEVVFSKPFGFLKKGADIAGAFAASEAQSAYVSAVGFFRWIHVLLLANPVMTGLGIVPWGHIVDTAMAAIQERQRNPDGRFDASSHWFRMLKQNPGRMDRHEIDSAAFNAVAAGSDTVSSGIQAFLYYMVRHPTAWQRARQEMLDAGLGERQGPVSLAETQGLPYLQACCKEALRVFGPGAMGLARRAPPGGLEIGGTVFPAGTTLSVHPWVIHHSKEIWGDDAREFSPERWLNPDAARLDKDYMPFGLGYASCPGQNLARMELAKIGATIVLNYNLRQVDPNQEMRYKAFFSLIAHMPPCYVEKVRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLE4</accession>
    <name>A0ABR1WLE4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668821.1">
        <property type="nucleotide sequence ID" value="XM_066809898.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042958"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="79" mass="8375" checksum="0E12F8263A14FD37" modified="2025-10-08" version="1">MEDKVGPANLLQDVGIKTPDMRCSGGGLGGDGDTSDQSDSSGQPTSRASAIPAGQQWRRAQRIIARRDLKRLLPAEIVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLE7</accession>
    <name>A0ABR1WLE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005599</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668837.1">
        <property type="nucleotide sequence ID" value="XM_066809914.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042974"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="19"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="370" mass="40030" checksum="A28E99DFD9F08BA6" modified="2025-10-08" version="1">MATAQDYKFEGWQAHDATSADGNMRWEEFEPKPWEENDVDIRVTHCGMCGSDLHVLRSGWGATPYPITVGHEIVGVVVRAGSQVMNGLKVGDRVGVGAQGDSCLSRFGDGARCEDCDALEENYCPRMVFTYSAPAPHFNGGKAQGGYATYHRAPSHFVVKIPDNVDSAEAAPMLCGGVTVFAPLKFHDTRPGKSVGIVGVGGLGHYGVIFAKAMGADRVVGISRRENKRKEVLSLGADDYIATLDDPNWTAKHARSLDLIISTVASSDSPIDDYFTLLKRDGKFVQVGIPEDGPFKLAAPSVVFGRQSFTGSMIGSPADLREMLELVSKNNLKGMIQLRPMSEANQAIQDLEAGKPRYRYVLVNETEASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLH4</accession>
    <name>A0ABR1WLH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trafficking protein particle complex subunit 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668869.1">
        <property type="nucleotide sequence ID" value="XM_066809946.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043006"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581">
        <property type="entry name" value="D-ALANYL-D-ALANINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="44376" checksum="BDC179B983A1CB56" modified="2025-10-08" version="1">MVHIADIFGWLAARPRSATKGPLDADEASTPSGIVPVTERDFSHLLRPEIFHQLSPLSIPPPFRNTTKQPTPETPIAELLAHGQFRAAAIASVQALTSSPVSATIAAAHPPVDPSDYARVFSLFYIRLACLCLIDSMPLAAQEAKALEDLNQAYYLDPITGAHLMPWELRLLAIRLQTIGFGDPRRAIMSYYDMAREAHLQIGKAAKAHENTDLELWKRRLVELGIKVGGALIEMEDLAGAAAHMATLRDTAQDGKLATAKALLWLHLGDVDAASRCVRDGKGGPVCEKVVLALVDMANGHFEDGLKKWTELKAELEENGIQDEMVGANLAVCLLYLGRMQEGRQILESLVDEGQSSRTLLFNLSTMYELCTDRAKALKARLADRVSNLEPTSHGWEKTNADFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLP5</accession>
    <name>A0ABR1WLP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668968.1">
        <property type="nucleotide sequence ID" value="XM_066810045.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043105"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045167905" evidence="1">
        <location>
            <begin position="21"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="171" mass="18610" checksum="2F17D06916215687" modified="2025-10-08" version="1">MKSVATIVFSFLATALTAVAAPAPAPALEVHQAHDQDRPVITTPDTIIPLRLLDRDGNYTKTIEPRAIATGEDNTRQQQQFTFSSGDKDAPYMVCSRIPRAHAGCVVRVWFDSHHAEEEGRPDDGIYSEPSDIVFDSEEDESEPCVALGVDSGDGKGEQGLMVRKIDVNCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLP7</accession>
    <name>A0ABR1WLP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668928.1">
        <property type="nucleotide sequence ID" value="XM_066810005.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043065"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046459627" evidence="1">
        <location>
            <begin position="17"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="150" mass="15706" checksum="D359B505EC6F94A2" modified="2025-10-08" version="1">MKSVLITAALLPLASAGAVFKPRNNNNGCNADNCARAVTGTRRGPESMSSFRQDCTSFMSTTVTPPMSTVIVTTTADSCDEEEDVAPQTLLKRVQEKRAEAVTVFPTAVPTYASACSGAVRYSSACSCWGVTAAVTTAPTPVITVTITVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMI1</accession>
    <name>A0ABR1WMI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-ketosteroid-delta-1-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669254.1">
        <property type="nucleotide sequence ID" value="XM_066810331.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043391"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014614">
        <property type="entry name" value="KsdD_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009472">
        <property type="entry name" value="PRK12834.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260">
        <property type="entry name" value="3-KETOSTEROID-DELTA-1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260:SF1">
        <property type="entry name" value="KSDD-LIKE STEROID DEHYDROGENASE RV0785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036654">
        <property type="entry name" value="UCP036654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="3">
        <location>
            <begin position="14"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="574" mass="62973" checksum="46FA3FB2795A7F46" modified="2025-10-08" version="1">MASSNDQTRQQKPVIIVGGGLAGLVAAFELAERKVPTLILDQENEGNLGGQAFWSLGGLFIVDSTEQRRMGIKDSRELAMRDWLGSARFDRDREDFWPRQWAEAFVNFATDEFESYVKARGLGFVTNVAWAERGAGTAESHGNSVPRFHISWGTGPEVVRVFAEPVKEAAKKGIIEFKFRHQVDELIVDDAGRAIGVRGSILEPDDAMRGVKTSRTVVDQFEIYGSAILVSSGGIGGNVEAVKAAWPKDRLGPRVPEKFVIGVPAHVDGRMIGITEKVGGNVVNRDRMWHYTEGLTNWNPIWPGHGIRVLPAPSSLWLDATGKRLPPFLYPGSDTLGTLKHICSTGYDYTWFVLNQSIIAREFALSGSEQNSDITNKSIWKLLTRVFGKKGTVHVQDFQKHGEDFVVRDNLEDLVAGMNELAKQSGGPPLEYEQIREVVAARDGQIDNAYCKDAQVMMIRNARLYFPDKISRVAPPHRLLDPKYGPLIAVRMNLLTRKTLGGLETNLRSNVMRDNGEPFPGLYAAGEVAGFGGGGVHGYSSLEGTFVGGCIFTGRVAGRAMADEVLGKPMTASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMI5</accession>
    <name>A0ABR1WMI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669230.1">
        <property type="nucleotide sequence ID" value="XM_066810307.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043367"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="307" mass="32549" checksum="A95E2B5A35E8D3CD" modified="2025-10-08" version="1">MNIPSAIQSATPGLLSGADTACAPDGPIALGNIISDPRSPEIAINFSTPATTSALGNLVVHEAVELDQTRTLDNSNNVQPSVWAKFLSGLVPGLGDIGGEAGVRAASGSTSSYSFEKIVTREIFPDLETVRTAFGDEQVQQSIKKRHWQLSVFMITGVQIAYGAEVLLNRARERGVYFQTGVDLTAATGGVAPVSVGAGLDTSSTSSQSLSTKYQSPLSSRTGCGRSCTGGRRWRSSGMIPGGTSSGFETRMGIRVLAPTMAGSTRSNSAVWIKRTKMFRRYSIFARRILQLRRGILANRISAVRGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN21</accession>
    <name>A0ABR1WN21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669426.1">
        <property type="nucleotide sequence ID" value="XM_066810503.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043563"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="324"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="554"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="702"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="554"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="751"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="790"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="815"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="851"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="875"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="890"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="927"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="953"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1000"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1054"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1101"/>
            <end position="1115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1123" mass="122468" checksum="68BEEDCE80286207" modified="2025-10-08" version="1">MGLMEHWSDEEDPDNESDSGETVIANKSRWDLEFDDSNVSTAPETVSSHQDSGEGPSRRAQAAGGSPDDDGDDSDNGSNNSGGATRDNGEGPSRYNGEGPNRDNGEGPSRLPQAAGGAPDDGGGDPGDSSSDDSIDSGYVSDGRGRNSGDDDEDEDTDEDANDRDESVMPDVIEDDSDDSDSACHSDDGDDIALWPHERLIVEYRRKVDKIGGIRRKGKKRIRKLNRTIQTLRNCVTEKNSSIRDLEGQIRDLEQETQELRDRQRGIRPPPTPWTTLWQQGRPYLSEIYREACKQLNMSQVPTNVHPQLTLSLRELSQRQMNAAYGLDGGGGGDGNGDGNGDGNGNRADNMSINSEGDDGDGDSDNESDLFVRQESSAPPADRDEMPFRPFNFNGLPREVQEQIFRYLFVKTDLVHCLSRLDPRNPPLTPRPLHRFFWGGSQRQCSVTLAHRPNSVLRLLLICKRWLYIGVHAFYGLNTFAFSSLGELGRFMKGSGSRLERIVNVELFWHGAIMPRHPSLVNQRTLPLQFFCDTRRLKTLVVHLQERFPEDERRTRRKYEIQKEDDNGNDNSGVPYAGSRLDLKDPFKVLMEQTRIQPNHRQYRSIRTMHGLDFVYQLRGMTWVRIREAQGPVARQKIRDWSVVDDINAVATLPKEPGYAFASELDNLSPIAGLGNFVPTDDDKDIVRIWYADDDPMREILGMDDDGDTISVVSSDARSTPSISDHSDDGGSDDDDDPNTPSVDGGGDNDSGVDVDMNDLDDSGIDVDMADDSDNRDNTPSDASSTLGDDGNDLEDPEEDDAALDGINDGLDQMDMGDESESIDEDAGDDNMDNVSTTTDSSGDSDDSSRPNDTGLTGITSDYSSAVNAVNLGQSSRNRSNTVSSSAADAGDDAGDLGTIEDDKNEEEEKEDEGDLDGDNNKDRAGSEQSSLFVPQNNDDDLSVKSEQAPTHIKTDSDEEKHKIIDLTSDDSGGPSRAAAGDKSDASVVIKNENTGSGSGSDPGPSRRGPLVGANRDVPMEIDSDEHDNKPPQDTDSTMDNSDAESGRSSWQDAQSRSPSAAASSPSIAGSSSFFRRRRYSPGPGSGMQRSPKRQRTQTPSESGRASASEAGSCADSPISIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNU8</accession>
    <name>A0ABR1WNU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_006457</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669695.1">
        <property type="nucleotide sequence ID" value="XM_066810772.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043832"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053007">
        <property type="entry name" value="CYP450_monoxygenase_sec-met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8085186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="497" mass="54738" checksum="7806E61DD19972A3" modified="2025-10-08" version="1">MPSTLALAAAGVVAAYAFLRALAVFLRDPREPKAVIGTIPFISPLIGMLVEKGGYYIRLRDSLKLPIYTLCVPGPPIYVVNSLSLIQRIDRHILTVAFAPIQVRACEKAMGVGESGMAKIKKDTVAEEAFAPAAAPGPGLDALNRAAVGNFAASFDKIASERPKAVNLFHWIRHEIFSATMDASYGPHNPFRDPKNEKAWFEFEEGIMALLMDVFPGVFARKSLKALDQMVKEFTQYFKGDGHLEGSLLVKLREKHNAAFGLDTIDTAHCEIGQVAGGVVNTAPTVFWLVWQVLADPVVFADCRAEVAKLVRTDANGKHTIDLAEVRTECPILLSTWQEVLRYHGISIAARIVQEDTMVDDQFLLKKGGVVMMPNAVIHSDQSLWGPTVGQFNHKRFLKSSAKDASTRRPAAAFRGFGSGHVLCPGRHFASTEALAFLALVLARFDVRPVTGEWKEPKKDMVMDRACPLPKTDVFVELRPRDDKEWRVVFSDTRAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQL7</accession>
    <name>A0ABR1WQL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670227.1">
        <property type="nucleotide sequence ID" value="XM_066811304.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044364"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466:SF1">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="52957" checksum="FB1B73A5AD99E670" modified="2025-10-08" version="1">MRLPECLIWYKKPEYRDIKEYSTAIVNGRRSLSPDGRGKVSIPRSLTLERVLANKTCSPLSLYDFYMYLKYIEYSPENLEFYIWFKNYEKNYQHGATGRGDGGLHITDSATTLAEEKSNGDASSVDTKHKNYDPEIGTKRPNWNFFIALLHEFCHGLLTWVSPTPAADETVEKIAQLISPETKCARGQACRHSAQTFHDDEDNDDEQELEGTHTSTRVGGKGLSWQQAMRPTTEGGLIPEADRSHRAELSAVVHTFLRAGARSELNIPPAIREQAVQALRTSDDPACLRPVADHVYGLLRNCSHRNFIRLGVGNGTFETLCMATSVGIAMTLAGFLCALLLAFTPREHAHSRADVLAAWPLWWIGISLILSGLRGSCFFLLLFSRRQPLPWERYDDDPAILSEHARKSRFMRFVSRMMIFDRKWKVQDQHLRNLQRKIVTQSLIGGAIFASLGVLIFVFLPVWREPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRI6</accession>
    <name>A0ABR1WRI6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal L27a protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007063</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670301.1">
        <property type="nucleotide sequence ID" value="XM_066811378.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044438"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_uL15_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="6">
        <location>
            <begin position="72"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="149" mass="16841" checksum="DFE1C7349666863E" modified="2025-10-08" version="1">MPTRLSKTRKHRGHVSAGKGRVGKHRKHPGGRGMAGGQHHHRTNIDKYHPGYFGKVGMRYFHKQQNHFFKPIVNLDKLWSLVPEETREAYLKGEKKDTVPVIDLLPLGYSKVLGKGRLPEVPIVVRARWVSRLAEKKITEAGGVVELVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRZ6</accession>
    <name>A0ABR1WRZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">D-malate dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="4">1.1.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_007002</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(R)-malate + NAD(+) = pyruvate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:18365"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15588"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.83"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.83" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670240.1">
        <property type="nucleotide sequence ID" value="XM_066811317.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044377"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050501">
        <property type="entry name" value="ICDH/IPMDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011829">
        <property type="entry name" value="TTC_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02089">
        <property type="entry name" value="TTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43275">
        <property type="entry name" value="D-MALATE DEHYDROGENASE [DECARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43275:SF1">
        <property type="entry name" value="D-MALATE DEHYDROGENASE [DECARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="11">
        <location>
            <begin position="9"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8085731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="39050" checksum="3A0A781806B0700C" modified="2025-10-08" version="1">MVPSNKPLKIAVIPGDGIGTEVMPHGVRCLQAAAKAFRLDLEFEEFDFASCAYYRQHGDMLPADWKTTLSRFDALYFGAVGMPDQVPDHVSLWGSLLKFRREFDQYVNLRPCRLMPGVPSPLANRKPGDIDFWVVRENTEGEYSSIGGKIFAGTDRETVVQETVMTRTGVDRVLRYAFDLAKSRPRQKLTSATKSNGISITMPYWDERVVAVEKYHIDILTAHFVQRPDIFDVVVGSNLFGDILSDLGPACTGTIGIAPSANLNPDGEFPSLFEPVHGSAPDIYGKGIANPVGMIWAGQMMLEHFGYTDAAAAMLKAIENVLSRSEPEVITADMGGKGTTKSLGEAIEQEILKLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WSA1</accession>
    <name>A0ABR1WSA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007045</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670283.1">
        <property type="nucleotide sequence ID" value="XM_066811360.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044420"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF30">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="5">
        <location>
            <begin position="29"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="199"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="283"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8085774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="324" mass="34797" checksum="9014038DF5A28152" modified="2025-10-08" version="1">MTLVAVLGATGAQGGSVANRLLASPDTYKGAEVVFADVNDAATLAPALEGVEALFVVTAYWPSIPKLGRDGAGDEEVAQFQAIADAAAKTPTIKHVVLSTLPRCAKMSGGKFPVPHYDYKQIAVDWIRATHPALWAKTTEFWPGWYTSNLATLMRPVPLPGTEGGYLLPLPSKPDAMLPMAGNLQLNAGLLVEAVPARARQDGRQDRHLHHRLPAHQLGRRQPHQTDGRRQTGGLRRGVGRARGEAVRRLRDRDGGAAPVERGVPGLAPVRAREDPGLGGGPRAREGGEEEASQFREVARGDQRSDVLESIEKEKEKGLQPVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWY1</accession>
    <name>A0ABR1WWY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1479-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670481.1">
        <property type="nucleotide sequence ID" value="XM_066806863.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039923"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010856">
        <property type="entry name" value="Gig2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613:SF1">
        <property type="entry name" value="DUF1479 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G09280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBIU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07350">
        <property type="entry name" value="Gig2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="54936" checksum="E564EC9F44FA2F13" modified="2025-10-08" version="1">MSATQTQTQTQTQTQTSTSPPPTTSKREGDISDSFVSLSKTKRPPLPRRFLELKQSLVQGREDAVIASWGRLLRQLRSENELVAAKGPGVVPVLQFNGLETQLPALRDELQKRGVAVIKGSEIEEYVRQNPSTRAFPPEDPQVYELYWSSPQLKVRAHPNFLRAQTLLMQHLWHHTTTSSSSSSSSSANALVSTSQPLAYADRLRIRQPGDARFALGPHIDGGSVERWERHGYGLGAHGRGVYEDVFAGRWEDHDPWDAGARVGAVSDNYRGLGACSMFRMFQGWLSMSRTGPREGTLMVNPLLRLATAYVLLRPFFEPVVADTRKEGYLGEENWRFCDGDTMTSALQGAEPGFGQELSAALHPHLDLDRTMVHMPPVEPGDFVVWHCDTIHAVDKVHTGPSDSSVLYIPICPVTEQNAQYLARQRQAFLDGTPGPDFPGGAGESEHVNRPTVDFLRRYAGVEGLRAMGLERLEPHPHDHAGAQNVTKRANQILGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX41</accession>
    <name>A0ABR1WX41_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670628.1">
        <property type="nucleotide sequence ID" value="XM_066807010.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040070"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045672973" evidence="1">
        <location>
            <begin position="26"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="23916" checksum="C7949D0D40926C1A" modified="2025-10-08" version="1">MKFNTLNIFFILLPVLLLHVKHAIAGSEVAHSVERALEYLDYLAEEEYDPGSGKRQYTISPGCVGSRPGGRCTLSEFLLYNWQGPSNTPSPKGYHIWPSMPSDITTLSAKDLAAKIHAARFDIRTKKGRYYEPASKIDPAKILPSNPQLGYLDIQAKLGAPLNQLSSSRDGKLNSYQSRIFNLGKETAQGVLELHYADQERFKLEAWQKKLTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXA8</accession>
    <name>A0ABR1WXA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aflatoxin biosynthesis ketoreductase nor-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670675.1">
        <property type="nucleotide sequence ID" value="XM_066807057.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040117"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="247" mass="26252" checksum="FE8FE63536B5FFAF" modified="2025-10-08" version="1">MSSQPCTVFITGANRGIGRALVEAYLARPNHSVIASVRNPESTTLKDITPAAGSRLLIVKIEAKSAGDPAAAVEQVKAAGITALDIVIAVKDIDTEQMAEILQVNTFAFVTLFSAVHPLLKAAAADDHDSAWPGPPKLLAISSNASQIVDMAPTIPVRVGAYGASKAALNYLVRRAHFENPWLACWVMNPGFVRTEPGNEAARLFGMDGAPDALEDIVPALMRTVDEATVEKTSGNFYNFDGAEMTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXC4</accession>
    <name>A0ABR1WXC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_002756</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670689.1">
        <property type="nucleotide sequence ID" value="XM_066807071.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040131"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="254"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8087795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="432" mass="48274" checksum="CC8B4FBA54FD2D0F" modified="2025-10-08" version="1">MDNYEPASSMSSFPTQDQEDWSIYYGYMDNAAASLGFDPAVFAGAPSAVPDCAGYVSDMQNPPTSVETHAPVSPNGTLRHPSGGCAEHSNGIGYNWTTPVSCDNIDISFTFPVIPYDTDSFIPDSPLPGTETGTNHDSYDAGAHVTQYDTMSPDQLAGPAYTSHPGVPLDAGYKTAQAVQSGSPSSRNEFHCGMHGCQMSFQGEWMLEDHQRFHAKHHWVVRESPFICECGQQCAKLDTLQRHIRRFQNASSDFRCHEPGCPSAFKRKDHLVQHLRHGHKFSDAELETKFPSRKVFTNTKPVCHFTSCEYNRDASFKHQTLVIQEAIKPFAKQADYTKHMRDVHEWSPYPCTIPSCDKQGKKGYFSQKALQKHKKEQHPDMEEEEPLGREPRAAQKVPCGMPGCNLMLAPSSVSRHRLLAHPLLEKKLRESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXE3</accession>
    <name>A0ABR1WXE3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Allantoinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002792</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670725.1">
        <property type="nucleotide sequence ID" value="XM_066807107.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040167"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050138">
        <property type="entry name" value="DHOase/Allantoinase_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668:SF2">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="56"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase 3" evidence="5">
        <location>
            <begin position="424"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8087831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="518" mass="54507" checksum="E528FB68B196FA0A" modified="2025-10-08" version="1">MGSIAYAAPGTAEPLTVLVSTRAVLTLPDESLVLTPASISVSPESGKIVAIVPALLIPGLVDAHVHLNEPGRTEWEGFNTGTRAAASGGVTTVIDMPLNAIPPTTTVAGFKEKLAAAQGQCWVDVGFYGGVIPGNADELLPLVEAGVRGFKGFLIESGVDEFPCVSSNDIALAMKTLNGTPTTLMFHAEMIPPIADSVGDAVQASEPPAAPHGDLTAYQTFLESRPPVFETCAIDEIVSLAPLAPALHLHIVHLSATQAIPILKAARKAGVNITAETCFHYLGLAAEEVAKGDCRYKCCPPIREQLNQDGLWDELQAGPDSVIRTVVSDHSPCTPELKLLPSHLQTAAEPAAMHHVDSGVDMSADADADANDLAQEAQLKAAAAQGDFFAAWGGISSVGLGLPILHSASVRRAQESLSAPDIVDIVRLCCAATAKQVGLAHRKGALKVGMDADICVFDEAEEWVLQSHGMHWKNRCSPWEGKAFRGRVRETWVRGRKVYEHGAGNLGFVGEAGWGGDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXN5</accession>
    <name>A0ABR1WXN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670794.1">
        <property type="nucleotide sequence ID" value="XM_066807176.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040236"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="664" mass="73629" checksum="55D22D53829C5717" modified="2025-10-08" version="1">MGFNESELKLAKEILLWIQYSTKLPHNMGFDWLRVAVGHDWDPNEKDAFVAAAIAACNGLVEFSDRGGFGFTHLTVREYFEQKSLDASGQEVLIPDKATAMLELASRCVEHLLAIAPSELPLDHCSRSIYESGETMLSFHKSFEAYVTEHWVYFLSSIPRESVWTLDRSGGTMCVEAQHVAQLRATIGRFLRNPLAVGLWIENLYALNFSTERIVESITNLTYSGVTQSHSTDKTLAKQLAAIAKDLQLVERDWGAKLREKPYLIWSDVVIFSKLDILSKLDTSRFGTVSSLLPRGAKNNGYDIPPLCSISSTLSAARVTGVLTIIPPAEFVRFWHSTDPSQAYTQGESFCEGWVANYEVWAQDSKFRLASFKIPLPQKEILVLFRQSFRHEIQYCLTGSENPDVLGLGHEVTIGPKKYKTSFPLAIGHDCLTFAVPGVASRPVHLKTELDVCPNELLYDGTEPDHLASLSFSVCGDFILARNATDTVVLPLPEGMKSNTELVQHVRPGKRKRSIEELGPDPSLGSLVHLASDQHLPERTLSGAHLSIARANATTVSLIPGGNNVSLELSSQGPLGEKTRRQLVALPNNLDTKDKAITVKFPETPDEHLRIILDKIGTESYTLDEDRRFSHPTVIKKNVGFVEPMNTSAAPGFMGSFFLDFSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYR7</accession>
    <name>A0ABR1WYR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671141.1">
        <property type="nucleotide sequence ID" value="XM_066807523.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040583"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646:SF1">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646">
        <property type="entry name" value="YALI0F00814P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="15972" checksum="3DD93A9258396D86" modified="2025-10-08" version="1">MPPQLVVACHLHLRMHRARSVVLTNDELVEIRAAQRTFEGAYMRTALSQFSFALIILKIFTSEFYAIGALFSCYGAAILLVAIYRRHQGNRQFFTAQDVAADGSGGTGEVQKKFRTSGNSVVLLTVLSLSAYITLIVLTWRLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ37</accession>
    <name>A0ABR1WZ37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pisatin demethylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003391</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671324.1">
        <property type="nucleotide sequence ID" value="XM_066807706.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040766"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="59997" checksum="AEE0D9054BC9D6EC" modified="2025-10-08" version="1">MACNTSSPVPRDVFYGHVLSIFGQGEKSKVLAIIFATVLITVVWHLVAYQLSPLRKYPGPILAGWTNVWRFCLALSGQHAPTIKKLHEKYGPVVRTGPNLLELDIPSLIRTVYNTDGKWKKSNFYKVNSTMVDGKILYNLFSETDTAKHATLKKPIVRHYSNSSVLATEPLMDEVLEDFCGHLEKRFIQQGQPCLLDEWLKHFAWDFISAVTFSKRFGYMEKGCDFDGSQDIGDRAQDYLGIVGQIPWLDHWLDKNPLVHIGPPNLANATRISAESLFPRLRGDDANFHPQNPDFLQYFIDSQTSHPDVVDSTTIIAYLLLNVVAGADTTAIVLKVLFYYCLRSPRVWQRLNADVLAAGLDPTRAPSYAAAKSIPYLDAAAREAMRFHPSVSMTVERIVPESGLALPDGSVVPGGTTVGMNPYVLGRNQAIFGADADEFIPDRWLQQDGETSEKYQARMRLWNASDLTFGAGSRICLGRHLSQMEMYKVIATLLTRYEIEIIDPTEDWKAVSRWFYRVDGGLTCRLRKRDNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ96</accession>
    <name>A0ABR1WZ96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671386.1">
        <property type="nucleotide sequence ID" value="XM_066807768.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040828"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="135" mass="14975" checksum="C6ADE4794BAF66E3" modified="2025-10-08" version="1">MLVQVVHIAQAALAVYGGQQSIQAIQNLQKYEDTTQKLAKYSNEAERQLKKTRATQAAGAITLLMSLVASVLLAFRGHSYGFLVRTLASPFMTGCLFLARHYNDAQKQTEDLVQVLEKLMFSWFATSVLCLLAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0D6</accession>
    <name>A0ABR1X0D6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Histone deacetylase</fullName>
            <ecNumber evidence="2 8">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003790</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2 8"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671723.1">
        <property type="nucleotide sequence ID" value="XM_066808105.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041165"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF36">
        <property type="entry name" value="HISTONE DEACETYLASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037913">
        <property type="entry name" value="His_deacetylse_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="9">
        <location>
            <begin position="86"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR037913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8088829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="495" mass="56048" checksum="895B3893E38534DD" modified="2025-10-08" version="1">MEPDPASPYRFRVPKPNYLPHNVDADEPIVETLNRPLDRPGEFENSHYFSKVKRMAHEYGITKPKGYNVTFHYNPNMERHHFGQTHPMKPWRLTLTKSLVTSYGMNFAMDNYTARTATYEELTNFHTNDYVDFLATPTPLDVDNMHPDLKFNLGGSDCPLFEGLYDYCSMSAGSSLDAARKICSKQADIAIAWGGGLHHAKKSEASGFCYINDIVLAILQLLRVYPRVLYIDIDVHHGDGVEEAFLSTDRVMTVSFHKYDPNTFFPGTGALDDNGPRSEHNPGAHHALNIPLNDGITDEQYSSLFENVISRCVEKFRPSAIALQCGADSLAGDRLGKFNLLVEGHSSCVEYCKKLGIPLIMFGGGGYTPRNVARAWAYETAVAIGQDKNIPHKIPEHTPWRERFRQDTLLPTIEQILGEPRQNRNPEKKLRDIVQHVTEQLRFVSHAPSVQYQVIPPDLGPIRDEVEQRLKEEAEIHDDNARKLREEAMGVPMEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1W8</accession>
    <name>A0ABR1X1W8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HAT1-interacting factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672318.1">
        <property type="nucleotide sequence ID" value="XM_066808700.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041760"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051730">
        <property type="entry name" value="NASP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019544">
        <property type="entry name" value="Tetratricopeptide_SHNi-TPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081:SF1">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10516">
        <property type="entry name" value="SHNi-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Tetratricopeptide SHNi-TPR" evidence="4">
        <location>
            <begin position="268"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="108"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="442"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="499" mass="53690" checksum="5C1CDB71F72C1AED" modified="2025-10-08" version="1">MAEPTPTDTPTLSAVPSAVVSAVGTPQSLPPMDAEEREKSIKVSLADLTAKAGSLYVQKKYDEASEVFAQAAEMQAEFNGEMSPDNADILYLYGRCLFKVGQSKSDVLGGKAGTEKKKPKAANGAAKSKAATAEASTAMALDDIKEEEQKTDAEKVAEEGVAIVAKNASGSGLEGGEKVPEAKKPLFQFTGDENFEGSDEDEDAEEEGEGEEEEEEDDLAVAFEVLDLARVMFEKQLEQGDADAADSKGKEKADDSTPSSRHVQERLADTHDLLAEISLENEKFPLAVNDTRASLKYKSALYPEESEVIAEAHFKLSLALEFASITTDSQDEDGQGPKALDEDMRNEAISELEKAIASTRMKLQNEEVDLATIHAPEENEASRKRILEVKDIIADMEQRLVDLKNPVDVEGALGAENPMTGLLGAALGESKAETEARIQEAKKNANDLSGLVRKKEKKAEAEAEAEAAESNGKRKAEEPALGVEEVKRAKTEEPQPAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2R7</accession>
    <name>A0ABR1X2R7_9PEZI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004603</name>
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    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672536.1">
        <property type="nucleotide sequence ID" value="XM_066808918.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041978"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="82" mass="8667" checksum="681BC5A8F47AAE69" modified="2025-10-08" version="1">MVVPATCYVEDAQSQEASSSDSPNPRRAAAEQVSAITGGELDYLIANAAYIPTVDGCYCAIGQMYDPTTGATVPSYNPMQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2U6</accession>
    <name>A0ABR1X2U6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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            <begin position="69"/>
            <end position="78"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="303" mass="32961" checksum="3FC65B81C12B081A" modified="2025-10-08" version="1">MSLARAFTTRRNKQSIDLKDAGAPQRSNTVTRGLGYSGSIRNKISSPMELTHTTNMLAYNAPDLNPLSARSVSSSASKTSDDESEARTSTSSPPTSPDVASVEERSNNPEPNHLSCYFTAPGQKPPPRVNEAPSIPKRAPSHTKKASFDNLAQRQAAARYSNQSLHTASSKASFSLSRSSSTSTTATSVSSHSYSRSKPIVPVMPASPTAPAKTISSPVRQRSMRRHDIAPANHPFGQELAQVSEIAEDYGVSDKLDLVREEQKELASKGLCSFKAEEYAAEVQSLFTTFFQPEPYRPQEIWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2W0</accession>
    <name>A0ABR1X2W0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004721</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NFYB/HAP3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672654.1">
        <property type="nucleotide sequence ID" value="XM_066809036.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042096"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="HFD_NFYB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027113">
        <property type="entry name" value="Transc_fact_NFYB/HAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003956">
        <property type="entry name" value="Transcrpt_fac_NFYB/HAP3_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064">
        <property type="entry name" value="CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064:SF9">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CCAATSUBUNTA"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00685">
        <property type="entry name" value="NFYB_HAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="6">
        <location>
            <begin position="50"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="134"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="21109" checksum="F51A84DDAECFFB77" modified="2025-10-08" version="1">MNDPQDPHASALGYEFEVKEQDRWLPIANAQGASRLDKFDVYDANIRNFAPVARIMKMALPENAKIAKEAKECMQECVSEFISFITSEASEKCHQEKRKTVNGEDILFAMTSLGFENYAEALKIYLSKYRESQSNRGDNQQARPSSQGYGASGPGGGAAAGASGFQSGEAGGLAEGGENYLYSAQGGHNGAAGETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X342</accession>
    <name>A0ABR1X342_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672732.1">
        <property type="nucleotide sequence ID" value="XM_066809114.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042174"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="463" mass="47840" checksum="881F6854E98EF75C" modified="2025-10-08" version="1">MAEAAAPEVAPVPEAAAPKADAVPKADDAPKADDAPKADDAPKAKAKAAAKQSYSTDPALYIYTSLTAGSSHIVTATSRLETILRANRVPFKALDMATDEKARMLWGRRAGKDANGRVRKLPGLVQMGMILGDLVEIEEWNEYGELKQHVKIYYDEFTIPAKGAEPPPNPLKKKASNPAKKATGPAAAAAAAGAAAAASAAKNIPAAPPMPEKKVAAATAKKAGEGTKKAGAGGSTELPVRSIAEEAASKAKQVRLDSLRAKVHGAKKEADSSSSSSDKAKKEASSTSSTSGDKTKKEAASTSGDKTKKEETPTKKKTTVKATTVKAKTTTTKSSLSTTKKASTATASTASSSAKTTTPAKTTSASKTTTTVKATPAAKATPKAGSRSPPTEKADEAPANIAETVAAGEKTEETEKTEAKPEVSTSESSAETSGSDEKEESEDKKEEKKEDKKDDDETKEEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X356</accession>
    <name>A0ABR1X356_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_004811</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672744.1">
        <property type="nucleotide sequence ID" value="XM_066809126.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042186"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17953">
        <property type="entry name" value="DEADc_DDX46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056149">
        <property type="entry name" value="PRP5/DDX46/KHDC4_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23469">
        <property type="entry name" value="KH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="609"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="640"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="829"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="350"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="999"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="609"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="69"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="361"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="394"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="468"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1015"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1047"/>
            <end position="1056"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8089850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1241" mass="137366" checksum="C9FFA58398CFF839" modified="2025-10-08" version="1">MARLRDTRSPSPAGSQQSSRRPRRDDDRRDRDRPRDRDRDWDRRDHGRRRSRTRSPPDVRRRRPSGHSHNSDYDLQQRRHRDRDRDNDYRRRDLDRRDNDRYRGGDRDRRRSRDRFGDRNRSPPDVRRRRSRDRDAERDNRTRRDDSRNGARSRREGTADSHPRSRRGDSRERGSAPVDANKAKPSEVADSKSKPAPAAAQTDAEKKAERLAKLAAWKKKQEEAKQKEATPGGTRKLLAQMDEKANGTPLSASSTVASPTAAVASPVDEAILSPAAPYAGKFDPKAIAKKAAPKAHSPSAAPKLGAIVNPPQAATIPQTQAPKGKSMAHSPSRNLTDAIAVAASALPSAKTSRFGFQKQNAETEKALQKRKLDLDEEETSERKLAKLPSLPLPDVDDTPYEVQDEEDEEDVDDFAGDEEAEAAAARAAQERRDERIAQESAQQHDSMEVDQPPPEASNDLGAKSNGTAEAAAPAAPAADTMDVDEDEEDPLDAFMNDLDTKADVSKPFQSKSKSKKPEQEPEAYFSDDEYDFDRKDDAPDAFLATVAKARKKKDIPTIDYTKLNLDPIRKNFWVEPSELSEMTEAELVDLRLELDGIKVSGKDVPKPVQKWSQCALSRKTLDIVHELGFDKPTPIQMQAFPAIMSGRDVIGMAKTGSGKTLAFLLPMFRHIKDQAPLKENDGPIGLIMTPTRELATQIHRDCKPFLKSMGLRAVCAYGGAPIKDHIAELKRGAEIVVCTPGRMIDLLAANQGRVTNLKRVTYVVLDEADRMFDMGFEPQVMKILQSVRPDRQNILFSATMPRIMDSLAKKILKDPIEINVGGKSTVAPEITQIVEVRNEENKFIRLLELLGELYDKDDDARSLIFVERQEKADKLLKELMQKGYPCMSIHGGKDQVDRDSTISDFKNGVIPILIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNKGTAVTFVTEDQENCAGPIAKALDQSGQPVPEQILDMRRAFQDKVKSGKARDNSGFGGKGLDRLDQEREATRLRERKSHRTEGEEPEEEEEGKGKDDKKVDKAVSAIQAAASGISARDTQTKLPDLEPKYTIHKREEAPAPAAGGNNPLDKVSSAINAINARLNKTGQLRPGQPVDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGTYYAAGKEVPPGAEPKLYILVEGDTELVVASAMNELTRLLKEGTVAAADAESRAPASGRYNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X389</accession>
    <name>A0ABR1X389_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004833</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672766.1">
        <property type="nucleotide sequence ID" value="XM_066809148.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042208"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="94" mass="11105" checksum="4B4B3ACDFF84E41F" modified="2025-10-08" version="1">MGYDPATMVERGVVWAEDQDPFGHVMQSQYMHFLGTCFHRVMESYDEHLTEQEYDDMIHARTVVPVVRRYELDIRRQVKYPDSVSPAFGFVCQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X392</accession>
    <name>A0ABR1X392_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672745.1">
        <property type="nucleotide sequence ID" value="XM_066809127.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042187"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="207" mass="22269" checksum="25F0D91897803B94" modified="2025-10-08" version="1">MQRGCEVIVVPTSCPEPAKAYLRHHSAHPPPPHQNLPLVDFFAYLIVLALYIYALRWLARYASRHATVAYRHLQEAMGNICGKSSSDPDAFSTPGRIVGTTPAQPQRASLPPRVVGGPPRKLGGGNEPEAAAPSSSAAVEARKRAAEAAEVVTKARAKAASAKNSGKLGQQLAAQKKQSRQETLDEISQEERRARDAEQAAQARAHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3A9</accession>
    <name>A0ABR1X3A9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative phospholipase</fullName>
            <ecNumber evidence="4">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004837</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30909"/>
            <dbReference type="ChEBI" id="CHEBI:36707"/>
            <dbReference type="EC" id="3.1.1.47"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the serine esterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.47" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672770.1">
        <property type="nucleotide sequence ID" value="XM_066809152.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042212"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016715">
        <property type="entry name" value="PAF_acetylhydro_eukaryote"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF11">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018169">
        <property type="entry name" value="PAF_acetylhydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="500"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR018169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="540" mass="59014" checksum="2E4CB359D8F802D6" modified="2025-10-08" version="1">MKPFPEAETIRARPAPSWVPPVLRPRFTWRYVVCSLAIGYVLYSFVASRHIFAHPLPQYSGPHAVGAIDVEAAAASPRLVDPARFKATKENAFELRTVLFTLYYPASKGQHVLKHHHDWIPKPISVTAAGYAKFAHIGNFFTNVLFTGAIKLLVGNIKIPAGVDLPILGDKGVALDSSSSSTESSGILPGDGDEIEKILLERTGHTTHDGYPVIVFSHGMASSRTDYTHYAGELASRGYVVAMLEHRDGSSPGSIIQEAGRPDETRLTFRMSEVESAEGDDLKEDDLKKAQLDFRQAEVEEAVRVLRRINAGDGADVFAANPRREGAHLHDWAGRLNVDGMIVAGHSYGATGAMQALKDGPSEERPFRAAIVLDPGKQSGRLNDDIAVPILVVHSNSWSKKRSMFYGRAHFDTVRDIVAGNNDRGHASWFLTSLGTSHPSVTDAPLLEPFLLSVTTGAKINVYEALRQYVHVSEDFMKFLADGEKRNLLAEPAEFPEYDEGKGFGKWKPGQGDDDTTEKGASGRIGGSTGRFTSLLRKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3Y0</accession>
    <name>A0ABR1X3Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Luciferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673000.1">
        <property type="nucleotide sequence ID" value="XM_066809382.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042442"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048273">
        <property type="entry name" value="Luciferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040841">
        <property type="entry name" value="Luciferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17648">
        <property type="entry name" value="Luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Luciferase" evidence="2">
        <location>
            <begin position="189"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="277" mass="30833" checksum="4F16442B968E3E6C" modified="2025-10-08" version="1">MSLSYTHTGHVPSSSMVEVTKGSEDGLTISVSLRQDPLSVTLDGPAIFTLAISLILSLHFLQPSIIVTLIGLVPVALYIRNDYYNYLKLGPGGTPATVQGYLRINWFKLWALRDPLEPLQEDPTIEPAAGILRKSPLSLTGAAPAPMSSASHPNDSRENNASIGIGTSCFEKHGMGLFSRFPFNKTCQGEICHVHDTDYAMHMNLHPNDVKEVLEKGWGQRHPLACETWLRMPVPRQFMLVYAPRNMDELKIVCKIVEAAEWWVMAKEYEIDTLEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4K2</accession>
    <name>A0ABR1X4K2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit C</fullName>
            <shortName evidence="4">eIF3c</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 93 kDa subunit homolog</fullName>
            <shortName evidence="4">eIF3 p93</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Translation initiation factor eIF3, p93 subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NIP1</name>
        <name evidence="7" type="ORF">PG997_005286</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673219.1">
        <property type="nucleotide sequence ID" value="XM_066809601.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042661"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03002">
        <property type="entry name" value="eIF3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027516">
        <property type="entry name" value="EIF3C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008905">
        <property type="entry name" value="EIF3C_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058999">
        <property type="entry name" value="EIF3CL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05470">
        <property type="entry name" value="eIF-3c_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26569">
        <property type="entry name" value="EIF3CL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="6">
        <location>
            <begin position="568"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="768"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="795"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8090325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="828" mass="92651" checksum="4B220F42EBA98C1B" modified="2025-10-08" version="1">MSKFFAGGDSSSESSSDEEELYPRRRKKKPQGKADDSSEEDSDDDDDEDESEEDSDDEGAGKTGASRFLRGDSSDSEDSDEERVKTVKSAKDKRFGELEAIIKAIDNGRKINDWGSISSEFDKLNRQAPKIGEGKQIPKVYIKALVELEDFMNETIAKQKVTPKKMNATNARGLNAVKQKVKKITKDYQDQVDSFRKDEDAFMESEDEVPEPKVKKSKPTDLYLDETTAAEAANDDGFAAVGKGGKVLQFTPRTGADQDHGEAPRGGQHPYLSLRVLLTLVSARFDLSAGSTTSTMPLDQWKAAEKDLQTLFEILEKNKDHIVIEGAEEWEDDDKPPTIGEGEKYLKVPGSIVSYVERLDDELTRSLQAIDPHTSEYIERLSDEGNLYNTIFKGMLYYEHLQKDSTLQIPQDSVNRIVMRRLEHVYFKPATVVKILEENAWKNAPADAESAVTPAEGIIRARAMLCQIYFLALHDEYYKARDMMLMSHLQESINNFDVLTQILYNRTLVQVGLCAFRKGLVYDAQNTLQEICGSGRQKELLAQGVMIQRYSQVSPEQERLEKQRQLPFHMHINLELLECVYLTCSMLLEIPLLAQTGSSPDIKKRVISKTYRRMLEYHERQIFTGPPENTRDHVMQASRALAAGEWKKSINFVHSIKIWDLMPDTEGIKTMLSKQIQEEGLRTYLFTYAPFYDTLSVSTLATMFELEDRKVAAIISKMISHEELAAALDQVSATVIFRKGVELSRLQSLALTLSDKAAALIETNERTLEQRTQGTANAFDRRGQNQRGGHRGGRGGRGGGRGGGGNTGPRQAGGTQFTGGALGAAVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4Y7</accession>
    <name>A0ABR1X4Y7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673380.1">
        <property type="nucleotide sequence ID" value="XM_066809762.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042822"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="91" mass="9693" checksum="DA38F4BB54E4BE58" modified="2025-10-08" version="1">MQVPARAWLALLGASLALFCTVGFLNAFGVFQEYYTTYLRGQRSSSDISWIGSLSIFLLYAVSPSAGFSWTGSGPPSRYASAASGCYSPCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7Q7</accession>
    <name>A0ABR1X7Q7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001857</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673468.1">
        <property type="nucleotide sequence ID" value="XM_066806172.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039232"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="190" mass="20474" checksum="6CCD1F5E2B810678" modified="2025-10-08" version="1">MYLLKRIAVALSLAPIKPRAGSFMPLNITALASRNQVSVLECWQLNASVPTKAMSAMNYFIGNTTSATWSIIEPNTTPGEAWAPAIQLTMVMNGLIRITAPAPSIDPNCIDFLGNKLPTCPQVNVAYMMPGTLASSVIIAADMQNTSTLRGHFTEFPSNEQTVLVQAPFEGNVIPEHVVLHDGACMENQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7Z7</accession>
    <name>A0ABR1X7Z7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673559.1">
        <property type="nucleotide sequence ID" value="XM_066806263.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039323"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="72"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="463"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="496"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="529"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="572"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="605"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="638"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="679" mass="76083" checksum="0F8A017F9DCC8191" modified="2025-10-08" version="1">MGRTLTLSTCQSPTPIQVYMAQTNAFEYSPLNLDRPALRLLRLKAAPDCRQGPVIECELIEAFFDADFVPDYEAVSYTWGDSSTLHGIFLDGLEFSVTYNLWSLLHDIRYQGEDRMLWIDAICIDQANDRERGHQVQQMDKIYRNAYRVIFWLGSLTEPISALMDSLAELQKRMPGLNWAPTDYRWQLNWECIRNRFPVVRGTLRTGLKLLLERPWFFRVWVLQEVANARAAVVHCGHKSISARILAVCPKLLHFETDAHCQAVLDVMPGPSRGNSWWSRERDFFTLLKRFSRTEATREHDKIFALFGLCPEANAMISTDYNKTIPDLLQETVSFICGQNVPATAYLAYRTVQELRDNLDLLHNIALETLLKVSSASNVEAFLLEHNRLLTRPPTLISAAMSNKRHGEEVLKNIFSLRPGKPQSEEELAGALFSMTQNEDETAIRLFLDHGLSGCNIDSKDSNGNTPLMIASSDGRENISRLLLDRGADHSLRNKQRATPLSMASASGHKTVVQLLVNRGADLESRDFDNETALLLASQFGHTSVVEILLAHGADSNAKSRYAKSIFHLDDNSNTPLIFASRFGWVDIAQTLLDRGVDCNQKGWDGNNPLLEASVWGQPEVVRLLLDLGADHSAKNKSGETALLRAEEAGYKDVVQMLIDHGAAKTSPGQDANLSSDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8J5</accession>
    <name>A0ABR1X8J5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Bromodomain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_002152</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673763.1">
        <property type="nucleotide sequence ID" value="XM_066806467.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039527"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04717">
        <property type="entry name" value="BAH_polybromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037382">
        <property type="entry name" value="Rsc/polybromo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062:SF21">
        <property type="entry name" value="CHROMATIN STRUCTURE-REMODELING COMPLEX SUBUNIT RSC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062">
        <property type="entry name" value="SWI/SNF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="122"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="315"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="BAH" evidence="11">
        <location>
            <begin position="412"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="214"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="596"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="719"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="748"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="838"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="44"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="227"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="601"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="625"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="751"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8091791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="912" mass="103764" checksum="FBA472A5A94A0808" modified="2025-10-08" version="1">MADQNAKAADNAIEVRESIEAKAAAENEAKDAPEAMDTTQDGPGDQDADGEPDEDADGEADPDADAEGEEDEDAEGEEDDAEGTGTGTSEEPGSRRRGGMSSDMYIIIENTANYLSSYREKDGYQIAQHFQRVPNRRLVPDYYDVIKEGIAFSTIRTKKLKKQYSNFSEFVRDVAQICHNAQVYNRPSSHFFQDAGRLREVFKEELQKLVDDEAITPAEAVLPDLGELPEAEDSPPPEEDEGEEDEDDEDDEDDDDDSDDEGGRRRGRRSRQGRKSDARDEDAHKKRGRPPKVFTPLEARIHALLKGLRKFKHPDGELMILPFEKLPDKQATPEYYTHIKNPIALDAIKKKAKRKKYPNVDAALKDIELMFENAKEYNEEGSQIFQDAVELQKQARVLAEQEKARPDNEFEDEDGRRPLTEIVNRGEVWKPIVAQIYRTWEDKSGQKWVNACWYYRPEQTVHRFEKHFLEHEVVKTGQYRDHRIDEVVDRCFVMFVTRFNKGRPRGLPKDKDVYVCEARYNEEKHRLNKIKTWASCVPDEVREKDYEMDLFDVPEDCERCPHLLRDDAKPTDPLPKPTWGHPNAPPLIGAVHCREREANESPPPEPTPTPPPVAPVEPIRRPSMMQASSSQGDITMGNTPHHFQPVAAPPTPTPVNPAYAAPHFAPRPSASPVPVPQYGHPGMHNAHAAPQMPPQTPHYQHPPPQPAFNNYQYAANGTPMPHQPHQPHHQPHHQPMPMNASPMVGYDQRLAPSPARPAASGKRLQPPRPVEVYRLDDSLNERIPAEIRDQFQRDEAGRVLFFTQPPLERAHRGVSHESAGLGHSVRYLADRARGIEDRRAKRKARDELRKEEERKKAETAAEQKKLEMQEQIDVAADVLNKWIGTMNKENEALKQQYDGWSVRDEDIDAYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8Q7</accession>
    <name>A0ABR1X8Q7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673812.1">
        <property type="nucleotide sequence ID" value="XM_066806516.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039576"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="152" mass="17079" checksum="00DE2F01195A9FFA" modified="2025-10-08" version="1">MARRKKVILSIALGLGAVSGAVAIYKTSTLLTLIDPDFTCLCPPCPHLLETRRLIRNDDLNHRCHVPHNHLDVRDFTRIEGNTIVIASSIPVLQPLLNKICQTRTGGRQNTARWKYYMALFSGKAKLATAIQRRIREHEQLSDSGPRQIDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9K7</accession>
    <name>A0ABR1X9K7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_000016</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674104.1">
        <property type="nucleotide sequence ID" value="XM_066804331.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037391"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02877">
        <property type="entry name" value="GH18_hevamine_XipI_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045321">
        <property type="entry name" value="Cts1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF49">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="5" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="10 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046498920" description="chitinase" evidence="15">
        <location>
            <begin position="24"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="17">
        <location>
            <begin position="31"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="16">
        <location>
            <begin position="408"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="330"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8093331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="444" mass="46862" checksum="29037C1E1B283783" modified="2025-10-08" version="1">MTLRATLVLPLVTLLSLAASVSAGYNANEQTNIAVYWGQNSYGQAKSQERLSVYCANSKINIIPLAFMNGIKTPITNFANAGDNCTAYAGTQLLNCPQLEEDIKTCQNNGKTILLSLGGATYTEGGFSSAADAQAAATNVWNLFGPNTATANRPFRSAVVDGFDFDFESSTTNMAPFAAQLRSLMDAATAGSGKRYYLSAAPQCPYPDVAINDILVNVPLDFVMVQFYNNYCGVSSFRPGLATQWNYNFDTWDTWAKQTSKNKNVKVLIGIPANTGAGGGYQPASAIASVVAFSKQYSSFGGIMMWDMSQLYANSGFLDCVYAALASGGTSPPPTPTTTPTTTATPPSQTTPTTLTTTTKTPSCTAVVSTVTATVTATAGMATTTVYTTKPVEQTTTPAPTPTGSPGGTVNQWGQCGGRDYTGPTQCKAPFTCVKSGEWWSDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA33</accession>
    <name>A0ABR1XA33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MFS transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674210.1">
        <property type="nucleotide sequence ID" value="XM_066804437.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037497"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="53107" checksum="A78D1C4F430DA504" modified="2025-10-08" version="1">MFGPSAADAEKNGKTEDVSVAIDTGSEASRDDLSSGNDAAAASSPRDATAAAADTKPPPPGAGSSWSNGITGAMKSTLKRELRINNQRYALLEASEDFMTTLLILATGLLTDRAGGAGALFWGNLVYSIAQYQVFSSWFAPSGGFASTLGLELMIQKLGALAGTGSANIIAVRTGNFAWVFWIAVFINLFTNVVCAAYLWFVRRSAGKFGNVVDPATGERLKQKAKKLEVGKIFRLPWSFWSIMAYSLFTTSTAVVFKQNATEMAEQRFKVSAVTAGWYSALLQYAGFFIVPVVAILIDLFGQRVTLMVIGGLGSFITMALVQWAGAVQGTAAGFGIYAIVSSYSPTVIIDSMRTSLFHQTDFGSAYSLKIMMNNSINIIVRILAGVIQDRDHNSYNHVVILYLVLAGGSLFVSLVLAGLAYFSVDLGALQWNRKQRRARTERLLEMKRAFYEAKGARNRFISRTCFGVLICLLLGGWAAYIWGAVTGAKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAL4</accession>
    <name>A0ABR1XAL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome P450 67</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000337</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674425.1">
        <property type="nucleotide sequence ID" value="XM_066804652.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037712"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF78">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8093652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="382" mass="43020" checksum="868ED558EFF4FCE8" modified="2025-10-08" version="1" fragment="single">TRNLRPRIKSHADLLVQRLRERSGRPVNATQWSMFFSFDMIGDVGYGKSFDQLATLEEHPAVKPIHGNMSELAILGQVPWLLHLLSSIPGGMKAFDDTANFCQGQRRTKQKTWSQDDYPQDIVSWLLKAMSEKDGSGPPSLGALDEDTKLLLIAGSETTATALTNALFFASMHREKQEKLRAALTESTCAETNNWSYEAVQSVKYLDHFINETMRLKPSVILSGRYETPPRVRIPGRVVVTAPLVWLHRDPRYWQRPDEFLPERWGRTGGRRWGRMGLLTFPFLLVSTLFILHHYINALRGLSFHPLHGFVITKPYTLANGGCVGKNLGLMTLRIALSAIIQNFKVSFAPGETGVVFDNEALDTFTTTIQPLKLQFTPLEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAT2</accession>
    <name>A0ABR1XAT2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Glutathione reductase</fullName>
            <ecNumber evidence="3 12">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_000419</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="3 12"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674507.1">
        <property type="nucleotide sequence ID" value="XM_066804734.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037794"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01421">
        <property type="entry name" value="gluta_reduc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="14">
        <location>
            <begin position="9"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="13">
        <location>
            <begin position="356"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00056905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8093734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="469" mass="51123" checksum="59CB8EBF5DABF28F" modified="2025-10-08" version="1">MAPISKETDYLVLGGGSGGLASARMAAGKFGAKAMIIEGGRLGGTCVNVGCVPKKVTFNAAMLAEMMHDAKAYGFSVEETKPFDFTSFKHKRDAYVKRLNGIYERNLNNDQVEYVRGWAKLLSKNEVEVTMEDGTKETVRAKKILVAVGGNPTIYPSDIPGSDLGTNSDGFFDIETLPKKVALVGAGYIAVEFAGMFNALGTETHLFIRHKTFLRTFDPMIQEGVTNEYERLGIHLHKESKQTKVEKDSNGKLTIHYSDSNGEGKLDGVDHLIWAIGRTPATQNLGLEKAGVKMNDMGHIIADDFQNTNVENVYALGDVCGKAELTPVAIAAGRRLAERLFGPEQFHTAHLDYSNIPSVVFAHPEVGSIGLTEPQAEEKYGKENLKIYKTNFTAMYYAMMEPEDKGPTKYKLICTGPEEKVVGLHIMGLGSGEMLQGFGVAMKMGATKKDFDSCVAIHPTSAEELVTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDG4</accession>
    <name>A0ABR1XDG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675430.1">
        <property type="nucleotide sequence ID" value="XM_066805657.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038717"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="166" mass="17868" checksum="E617E0D5579CB639" modified="2025-10-08" version="1">MAGAIQCAFGDDWDEVVVNVFEHDTDFELGKPSHEDRIQNCEFENSTLAHKVDNWMNLLSSRSEQENTTTTRATRAEPATEVPRPPGPPGICVVCEGQRYLEFFGLPRPPAPPPLLLLLLVLLPPSSFSPLSLAGEGGGGGDDDDEEEEKAAPAPAPAPAKRASSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDU0</accession>
    <name>A0ABR1XDU0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675574.1">
        <property type="nucleotide sequence ID" value="XM_066805801.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038861"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="190" mass="21654" checksum="1CDF8D4F3B5ED5B5" modified="2025-10-08" version="1">MERSHFAKPRSFCEEQACRMEKLDDRIKSQVLLHKQDALRLGKDLVLVLFSHGAECTYLSRYFPSIAPEFRTWLDVQQLAKANTFRSQPPALKTCLTLCGYHWMDLSCGTSRVTGEDHEGKERHANAHNADINACMTIALLERILDPQHRERLAQKQAMQAIVHSSETPPPENPLPLLLSPQTYNGFQNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEM7</accession>
    <name>A0ABR1XEM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675846.1">
        <property type="nucleotide sequence ID" value="XM_066806073.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039133"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8095073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="103" mass="11040" checksum="61531181B1787628" modified="2025-10-08" version="1">MFSRSAALRSSIRATRVSPARISHKPIMGARKYATEPEPTPKEGGITKSGSNTARTIAGLLGVSIAGTFAFLLANPRKAQEVGGNYHPQAIAKEERLNQQRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQJ4</accession>
    <name>A0ABR1UQJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_015415</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660614.1">
        <property type="nucleotide sequence ID" value="XM_066819729.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052789"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.450.10">
        <property type="entry name" value="Glucose Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027424">
        <property type="entry name" value="Glucose_Oxidase_domain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF201">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046773178" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="7">
        <location>
            <begin position="16"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="8">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="9">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8061194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="604" mass="64489" checksum="19DCA2C64ABC83DF" modified="2025-10-08" version="1">MRASWTLAFISLAAAGCVKRAPAGGLVDGTDGTYDYIVVGGGTSGLVVAKRLSEDPKISVLVLEAGGSLENNANVTNPLGYGLAFGTEIDYAYQTVEQKYAGGKPQTLRAGKGLGGTSTINGLAYTRAESNQIDLWEKMGNEGWNWKNLLPYYVKSERLDVPNAERLEGGKMTFDAAVHGKEGPLKTGWLFGTTNSTLGATLNTTFAAMGVPWNADANDGSMAGYTDLNIREDAARAYYFPIRESAKNLKVMLNTEARRLTWKAAGNSTAGTQTAEGVEIMTQDGKTMVMKAKKEVILSAGALVSPLLLEKSGVGNKEILAAAGIKSVVDLPTVGENLQDQANNGLKFGIANNFTETDKNAYVAYPTAEQVFGKDNVAAVAAKVKAALPGYAAQVALVNGNVTKAADLEKFFNMQYDLIFDEAQPNPIAEVLLYQQGGVWDSEYWGLLPFSRGNLHVTAANTSTTSATGAKINPNFFMLDWDVTQQVGAANFIRRMYGTAPFKDVVGPEDTPSVKTVPADADEKVMGDWLKQNYRSNFHPVGTAAMMPREVGGVVDSQLKVYGTANVRVVDASILPFQVCGHLVSTLYAVSERASDLIKASAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1USZ4</accession>
    <name>A0ABR1USZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660656.1">
        <property type="nucleotide sequence ID" value="XM_066818468.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051528"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="151" mass="17374" checksum="3AAC35A71C82B18D" modified="2025-10-08" version="1">MAAGAKTAVITQNYFLDSGISIALNAYNVRVPKREQRVWAYFHWRGAQSCLDVPSLPGPGFDWTSTDSQAKTGATSETRARISAQLYREQIGPWPSVINFPFRWVPNGRKYRLWCYIHRHEKPAGGRYDDIVYSMSVWDRELRIIIIIIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT72</accession>
    <name>A0ABR1UT72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660730.1">
        <property type="nucleotide sequence ID" value="XM_066818542.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051602"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="697"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="744"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="761"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="777"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="825"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="930"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="977"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1060" mass="114039" checksum="27044A61F65DAF24" modified="2025-10-08" version="1">MNRFRTKKKAKEEAAAARPSQDSESPGFRFRKGKKPQEEPKPEIDISSALPSSDDFRTSLLMTGLSARFSMLREQDDPSTKIGKALDDSVLFPKRQSRMQDLGPAGALSALGGLSDIAEVESIRAPFARNDPYASDNDSTHGSIMTRAKPTEGNNLFGGRQKVYKIAAGGGGMNGRVLYDDDVALSAFQKWKRDEQKRKSLEGATDDGDEGSQRPSMEEPYPRSESPFSTSYNRKRETNSTQSSIPSMARNSTAATSITSQQPTPSMKDGQGGSTAPTSASSTPVLERSFTRGRRLYETGLNHELQEQQASALSRIDTLNRQRNLGARTPDLAQASPSPTATGFPDRLFGDRRILSKASAPQLRESEEIAALPIGPNDRGKATALGVFQKPAQPYDESRFAERQLQLQQGRDTPTQRFRTESNASRGSAFTPQPLETKTTPTLVEEPSASTFFDDSDASPVSGPKLHIERPVDNVHPAFRHGALPTPLSLGGKSDGEPSPTTEPASLSPQPQLTPADSPTLGPGAIAGLSGMVRQHLRADSGGSSIYGITSATEENDRHYVDEVNDYRDLVNNTSSWNPQHDSTAPASNADADKLAPPAQGKPNANRESRGADDFARELADGARRVREKLTSYVELDNGSTTSLALQDNREPSNAQQPKAAPFGLLRNKSSLNKMAGVGAPTSPPSMREDAAREAMADASGGNESEGNGEQHAGIRAFRQARRELQRSRSETPLPLSQRRPSEDSINISVSRSGSRGTVPLEHDRSGSDSSRERPGSRPSRSRNGSSPPGRLLESNEDTRQPMRSPGLPGTNIRRSPHMPPQAFPGSSSARTQQGLRVRPVQDSELGNPSPISPIPSSFAGLPASPRAFKTPNPGLNSDGTEVPGLNDNMKRTVKKREISEPKFVMSTSRVPTVSLPAEASANRDRCNSRSRSNSKSENSAPPLPPINPRRRQDGSGSKTRTIFGSLVGRKSDEHSTSAPSSRPSSSANTADDDVADKPVTRQLRKMASDAQGMQLNRPMGAPNSNGQFASMGPPASRMVVTQNAKDRERTSAVLPGGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVB2</accession>
    <name>A0ABR1UVB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7136 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661475.1">
        <property type="nucleotide sequence ID" value="XM_066819287.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052347"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055560">
        <property type="entry name" value="DUF7136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23584">
        <property type="entry name" value="DUF7136"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045359593" description="DUF7136 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7136" evidence="2">
        <location>
            <begin position="25"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7136" evidence="2">
        <location>
            <begin position="170"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="227" mass="24687" checksum="7892910CDC462E01" modified="2025-10-08" version="1">MHTLSQAAALLAACAVGGVHAASPTSGILEVDLAFPRNQTYAPTARLPIVFAYQNPELATALRARVSFTVWNWDNMGNTTASANLDLGQANLSSRDPFLHYDFFPGFEAEGHYLLTWTAGWDNCTEESLGQTYTSTRIAHRTKTHSVLFTISNSAPAIDLVAATDNKDFVAESMPTPSPCRVQIDSAAASSMAASMTARACKYTQVVPPRRESSVRQRTKARRSSWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVK6</accession>
    <name>A0ABR1UVK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">C6 transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_015066</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661568.1">
        <property type="nucleotide sequence ID" value="XM_066819380.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052440"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="912"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1298"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="916"/>
            <end position="937"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1331" mass="151823" checksum="E9E44033E62A827E" modified="2025-10-08" version="1">MRLGKTPISCTPCAKRKVRCDRLQPCCHCKRRPQDNCVYPEPAAESTPERLPNDVSDRIGKLERYIRSLGGDPEEAVRPDTRAIETSGLVTHNEEVTYIESPMWYSWSGASHSDELQNTSTGTGQSSPAVKSASWVRTILDPRESTDTSGLAWAVPLPSSHIFIFWKTFLKNVDPLVKIFFRWEVEPIIQKTHNDASSLCNEERAIVLAIVFISVSSLSGDECTKLLHDGKPQLMERYQNAAECALLLADYASTTHRLTLQAFMLYLLTMNCIARPPAMFALMGIATRIAERMGLHRDGDLLGLGVLRSEERRRMWWQLQFLEIAVARHVGSIPLSLFAGWDTKLPSNLEDADLAPDTKALPPGRRKLTGMSHCLWRYDILHAQREMRRAHDGDRGLTWLLSPRVPLADKDALLDEVETMLGTKYVRHCELLNPLHVLIQLGIGSYLLAARRTARQPALVNAKLSEMSRQERDDMLDICTKLMDYSIMARTTESIKGFLWHDDNYFQWIGFVYVLLECHHRFDQPEVVDLWDLVRRLHDVHPQLRTAIDRHEVASVARITIAAWQKYAAHAQQQQQQDETFEHPQWVLELCRNFGFSPVAEVAPTASVAVVSTEGQEQEDGNQFAGIDFDLDMFDWSIWEELNKNAGPLSTTMANITDVPPELDLIIEQLLDHPFLFNGNALATSCEPLWEKLGGTDVYRRAAEADRDRTRRAELICQDIFEGDYGWDSTEEKKKELAWLFQVARRGMGAQRASQIGWAFENATSIGKLFLDENWKPHTDPAKIQHKLESLTSKTFLNKAIVHCTDLEKLEQIIDAYVAVFPAAFTGACYGPLLELVPIHAAVYAKRLDVVQMLVSKGLAPAFVDSFFTYGQVEVRWDDDSRMFEASPFNVALSERDEDMCLALLDGADGPLCEVKEEDDDDDDDDDDDGYESDLSYDDFEERDRSEDVKLARYLKIAEANKMYRLIPALLQYWKWVCPAYQYSLRRILDLVSMNNGKDDPEWVTATARDGDGKQHIIHELALSFAVERAYWENAVIIYQYQARKGSVDSDDLAGVLVKAADHPYSGEGFFIRMWPECKQWLCKSASSAEENAQRVERCMRRCLEATIEIETTWGWNHWYPPQKSSREVSFHLLKAGVKPELCHLRAAIKAWDHDMLSELIARGDLDLRAKWSGFSDDDDKEELTPFEYALRRWYSVAGPARTRASPRPSMTLLLKLLYHAGVPEEVSEEARKVISQLFIVDFGLASHFKWHEQGRKIQARQLPQSAWDAERLVDPKVPSMEKLTTFHLLLQKEFNPDDDEEEFPALPSSKLPPYFPATKQQEQNRPPGYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVQ7</accession>
    <name>A0ABR1UVQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661607.1">
        <property type="nucleotide sequence ID" value="XM_066819419.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052479"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578:SF1">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045793452" description="Apple domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8063008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="20799" checksum="2C4E39B31E8EC829" modified="2025-10-08" version="1">MAPILRLAASLAALAGLAIADDINWSLFDAAGPATGFELAPVPMADASNYTTPIPLANSSIRAPLDCKAQDTYLGQQVFTDGPLSLTRCADACTAQRAWEAKHANKKPCRFFNTYTLLKVCSLYSETWAPGFGTDKGQWRGGDLYLIADSFVASFAPDPSSGECPAATATPKATITPTPTPSGLTTKTVTTTTTTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWJ2</accession>
    <name>A0ABR1UWJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS multidrug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014517</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661019.1">
        <property type="nucleotide sequence ID" value="XM_066818831.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051891"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF60">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="43"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="471" mass="52289" checksum="DA2C125F03208BF3" modified="2025-10-08" version="1">MTSPDSSQLSMEKKNDEEVVVSWDGPDDPENPLNWTWKRKWVATILVSCFTFISPFSSTMVTPALDQIGAELNIPKGFMQALVMSIFLLGYAQGPFVLAPLSEIYGRVCVLQYANLIYLAFNTACGFSTSKSQMLAFRFLSGIGGSAPQALCNGVIADVWTKEELGKGQTIYGMLTFIGPTVAPIVGAYISQSVSWRWIFWSTSLFDVAVQVTAFFFLRETYGPRILAKRAARIRKETGAQNVRTEYDDAKRSSGSIIRRRLVLPFIMLVAHPAVQAPSVYRAFLYGVMYLLLSTFDRVWQDIYGMGKTISSLHYLSLCLGFMIGLQISHPLIDGLYAWLKKYYKRTEGVPEWRIPPMLLGGLLTPLGLFMYGWTASPSIHWLVSDLGCVFLAAGLILAFQSAQAYVTDAYGARHAASAAAVGAFLRTMCGFSFPLFAPAMYDALGIPWGTIRSRIEFVRYPFKGIAFPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UY45</accession>
    <name>A0ABR1UY45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661302.1">
        <property type="nucleotide sequence ID" value="XM_066819114.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052174"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="5"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="366" mass="41081" checksum="B132760DCCBB8801" modified="2025-10-08" version="1">MGSSFDPFPRLPMELQLMVWKEAVLADHHYVLIDAASHFKHGFRRAAMGITPTPNLRRALLEVNQASRTVALKHCSARLDVWERPPHMLEDGEPPAVGLDMSDEQRRRVLRLYEAQDRAQELANRLLGWGEELAADELQLIYDALKPIAQQRATDATNEYLLSATTGLYSPWARVPWERPYGDTPVPTTRRGVVYLDPERDYFVTLTHFNKAARDAFPCDPLRRADFPCGDNKNKNKNNKNNNNTSMTTLYRAAAASSTLTPPTSLRRLARRGLQISPDFPLPRDFGAENALPYTDKYHFPQRRARGRLVPRHAEPRPVRARALPPGLCRLRRRRAPCGPGPPVRRAGPPGGRGLGVARLGGLSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UY51</accession>
    <name>A0ABR1UY51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin depolymerizing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661575.1">
        <property type="nucleotide sequence ID" value="XM_066819387.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052447"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11282">
        <property type="entry name" value="ADF_coactosin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF56">
        <property type="entry name" value="ADF-H DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="160" mass="17681" checksum="3F2094E95AD4AC29" modified="2025-10-08" version="1">MSCVNLDEVKAAYEQVRSDKDETNWVLLSYAEARGDKLALTATGAGGLEELAERLDEGQAQYAYARVEYANDSESKRVKFIFVVWIGESTKVMRKAGVSIHAGHVKDVFAHHSIQVTASNKGELKEESIVKRLRAAGAPITMAVAVRKGRRKTRQKAMLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1U9</accession>
    <name>A0ABR1V1U9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011924</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661931.1">
        <property type="nucleotide sequence ID" value="XM_066816239.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049299"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="588"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="120"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="612"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="648" mass="68128" checksum="10CE28EAD8417DFA" modified="2025-10-08" version="1">MVRDAASDTSDTLHEVERGGAEPTRDTAQTTTTTTTINSSPSIKQAPGANHGHSAHNVGTDVPTTGADGRDNVSPKGDTAVAHGDGHGTGNDGVTTQPQPPKTGTDAPEAGRTKLETTLIMAALCSALFLAALDVTIVATAVPTIVQEFASPVGYTWVGSAYLLANAALVPSWGKLSDIFGRKALLLCAVATFWLGSLICALANSMGMLIAARAIQGAGGGGIVVLVNICISDLFSMRTRGIYYGVLGMVWAIASAIGPVLGGVFTSKVTWRWCFYVNLPISAAGFAILVFVLKLHNPKTPLREGLAAIDWLGSLLIIGGTLMFLFGLEFGDVMYPWDSAAVICLIVFGVFTIALFFVVETRVATYPVIPLSLFQNRANVAAFAVSFCHGYCFISGSYYLPLYFQAVLGADALLSGVYILPYALSLSFVSAGTGVWMKKTGQYLPPIIFGMAVMTLGFGLFIDLDTTYNWAKIVVFQIVAGIGTGPNFQSPLIALQSSVEPRNIASATSAFGFVRQLATSISVVIGGVVFQNQMQKQRPQLLAALGPKLADQLSGGSAGGNVGVVAALRGEPGAVAKGAYWNSLQTMYIMYTCFAALGLLLSPLIGQKKLSKEHKEHKTGLKSLQPTDRDEEAAAAVNTSAKGEKETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V216</accession>
    <name>A0ABR1V216_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011984</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661991.1">
        <property type="nucleotide sequence ID" value="XM_066816299.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049359"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="GH92_a_mannosidase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF27">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G10520)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046105450" evidence="1">
        <location>
            <begin position="18"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="3">
        <location>
            <begin position="25"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="2">
        <location>
            <begin position="281"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="798" mass="86875" checksum="38023EEA23AB1DF7" modified="2025-10-08" version="1">MALKSVLLSALLHFSLAEVVDYAQYVNPLIGGSGPFEGLAFGGGDIFVGGALPFGVAKVGIDTYEPNVSFAGLVTGVSMLHESGTGGAPKYGVVEAGTINILDNRTYWQQRVGDDTARVGYFQTRLESGVAVELSGARHAGIMRYSFPTSNEERHVLVDLSHYLPQESGGPSSQVYLGGEISLNGATYQGHATYEGFDTPPDEAKTFRGRNTEPMARHHVFSNEPVGQAVFGPNAFSSNDTATMTASSGPMNDRVGAVFSWKAETPVVTSRVGISFISASKACKFKSEEIPTWNLNDTVDAAVAEWNRDVFSKIRVATEGESANRTNLVLLYSSLYFMHLMPSDRTGENPCGTRASHPGTTFTHFGEQFIPSSTRTVDTFRCTVSLYHLLQPASYEGQIRSLIDIWRHEGYMPDGRSGNFNGLVQGGSNADNVLADAYVKGLRGAINWTAGYAAMRKNAEHGPSASIKEGRGALDDWVGLGYVSVDGNTRCLSRTVEYSLNDYALSVVAAGEGAPGDVQKYLNRSAGWQRTWNHDVTSRGFSGFLTPRLANGSWNATGYNPALCGDCEWKSITYEATPWEYSFTVPHDMQSLIQYMGGETEFERRLDYIFQPNTSEQDLEANGAGITTIMNIGNEPDFATPYLYHYLNHQSKSVNQSRALANQYFHDALYGVPGNSDAGALNSWLVWQMLGLYPVVTQPVYLLASPWFADVNVTVNEDRTLRITSRGGGGNSSNPATALGHSGFYVQSVKVNGEPWDRNWLLHDAVMVDGGTIEFEVGDEPVQWEKGDVPPSPGHYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2K1</accession>
    <name>A0ABR1V2K1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Satratoxin biosynthesis SC1 cluster protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011914</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661921.1">
        <property type="nucleotide sequence ID" value="XM_066816229.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049289"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF124">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="45"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="355"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="460"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="506" mass="55804" checksum="52F1B1E5B7E70439" modified="2025-10-08" version="1">MADTPVIYMGEPPGGEDRWAAWSREGLMQGIGALTMTLATIACTLRVYARTRLIRQKLVLDDYLVCMSTIACWAFYALSLCSKSVSVRILMLFGVTRYALDVRYGRDADFMVISGQVWRSRSTHVANDDGGIHYAIKGEQLVTNPGPSVWQLTHKRNQFTLGLAASYILSSEVAKISILMFYFRISPDRRFHVAVGCMIGILSIYSALYILLNIFGCTPVSDAWNVAKQAAGEAQCIDKGKFYLAAVVVNVAIDFIILLLPIPVIAPLQMPMRRKISLCLLFATGGFTIFAATYNSVLTIKLFASDDYNWELSKELLWMYAELASCVICASGPTLKPVFTLVIFPRLGIRTSASRAGYREHQDGSGGKSNNSGGLKTIGSIASKPKPSRSRSRSRTDGAIELESEDDLSINNNNNNNQKSGGGGRRKTNTTDDQDKLWSRVANHGRDHSSQNFQITSTGTHDDDNGLEPGDDKWKGNDLFRRNSVGINVTREVDIAYDSTKPLDQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2K4</accession>
    <name>A0ABR1V2K4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short chain dehydrogenase atnD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662169.1">
        <property type="nucleotide sequence ID" value="XM_066816477.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049537"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="145" mass="16146" checksum="FE276F5285B92CB3" modified="2025-10-08" version="1">MLADTARRFPESRLRLVFVTSALASSVRDNLNSIRDNVFDGLNDQKKANMRNWLVRLYPPEKTGVVIGMINPGLCRTGLARYSTWHYRLYIDVMSVLLAARMAVTGEPDGSVRGRGRGGGAWEVSVGVRDQRVRVSSSGYSILRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2V1</accession>
    <name>A0ABR1V2V1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATP-dependent bile acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_012004</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662011.1">
        <property type="nucleotide sequence ID" value="XM_066816319.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049379"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="526"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="953"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1002"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1074"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1107"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="294"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="641"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1056"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1304"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="884"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8065257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1563" mass="170869" checksum="B8800293135BE94B" modified="2025-10-08" version="1">MDAIICPGPDRQGDQQRTSACVVLRSLDLLVPAAACLISAIVHVLGRYHDKSHRPVSLDSEPTSSNLLLPARPPYASNLRPSLSRVSISRPMKRLEITILITLVLTDLARLLDHEQFGSAVTLSISACLLALALARCLGFVGLDACLQPHSMTLYAVQVPCTAVLLPLAFLDHPDRQNMYLYYFIRIWLFIGLFVIHGFAPRVPQVDLINNNGFVSGSQDTASLFSLLSFSWATGLLWEAFRAGSLDAASLDPLRPEQTSAFIVLAYMSQKVRGARLAWQILRFLRLDILEQGLWATVTSVAVFVPPLLIKLILKYLEKEYSERIERSTAWFCVAGLFFSVSVSGLAEAQCGWKGNRINAKLRAVLLSQTYEKICKKATVRSSPPSHSAPNAEAQDASHTTDGTILNMVSGDIDHISVMSGSLYLVWVTFPVQITIGTYLLYRILGWSGVLGVLLMVALLPVNILISKRLAAVQGKLLSATDARIQASDELLRTIKSIKYYAWEFPFRERVREKRTAELNKLRTRFIWWSISMTVFYSLPFLSTLITFFLYTVVWRNRLETSVAFPALATFAVLRIPLNRLADSITFLIQAYNSLMRVERFLQEPEVNQRSRNPGSGSPMAVGFDKATLSWPCSNASESGMTAFDTSPGSAYFYYNNFALRCLTIEFRQGGLNVVYGPSGSGKSSLLLALLGEMHLEHGQVYVPPAGASNGWGSMGHMDKSNELINTTAYCPHEAWIMNRSIRANILLDQPFDSLRYQQVLDAVALGPDLAALAEGDQTLAGDNGSRLSGGQKQRVALARVLYSPSRLVLLDDCLSAVDSRTENHIFFYAIKGPLMQGRTCILATHNIQIALPHCDYAVELENGRVKTQGMADHILKNPFGDKPLSADASPADTPDKGKTTVSTEEVEALPASDTVVQTPSGPVGDYKSQESKFEGAVSWSVVRYYLNSMGSLWFWLLVLCGFATQQLAALGTNLWIKEWAFQSNNKNNTTTAKTANVSPSYYLAGYAAICTAYAAITFMRDMITLWGLPESVLENIRAPARLRPLRQVRLLQPPPLGQITNRFSRDVGVVDQLLASFSVSALQIAASVAMVVGLILWALPSLYMKVKFAVVFVAYCAVVRMYIGGARDLKRIEAAARSPLYQLVGETMAGRVSIRGYGLYESLLGREHAQAVDRLNGPFLLLSAAKQWLTLRINVLSSIILTATGALVVYSGPPGYSGSVDSGVAGLVLMYATSFTENMLWLAQIYAIIQENLTSLERIVEYTETEQEPIGKNQPLVDTTTTGRIGGNGLPEIPPNWPQRGDVSFKNLTARYEPHLAPALKNVTFHVNPGSRTALVGRTGAGKSSLALALLRGLDLDPGSAIAIDGIDIATLPLSRLRGEAVTVVPQDDAQLCFGSGTTARQCLDPLGRYGDAEIEAVLGSMQYRLDLDSAASELSRGQRQVLCVARGLLRKSKILVLDEATASVDHVADIAIQAGLRVYAAKTGTTVITIAHRLLTIADYDRVVVLDGGSVVEEGGIRELLLKKEKENSSEGGNGNGQSTALFRRLCEESGDFEAILDAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3N4</accession>
    <name>A0ABR1V3N4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome assembly factor mrt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012552</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">Associates with the pre-60S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662558.1">
        <property type="nucleotide sequence ID" value="XM_066816866.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049926"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05796">
        <property type="entry name" value="Ribosomal_P0_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033867">
        <property type="entry name" value="Mrt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051742">
        <property type="entry name" value="Ribosome_Assembly_uL10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841:SF1">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 MRTO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="126"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="246" mass="27335" checksum="40FC7F630C5036C7" modified="2025-10-08" version="1">MPKSRRNKVVHMTQVSKKTREHKERLLETIREAIPEYQHVFVFGVENMRNTHIQEVRKELQDDSRIFLGKTTLMTRALGRTPEESTADGLHKLSKYMTGNVGLLLTNRDSAALQEYLSNVTAADFARAGAVAPRGFTIPAGPVYSTGGEVPAEHDVPMGHTLEPELRRLGVPTRMVKGKIVLGEEDGSSEGHVVCREGDVLEARQTRLLKLFSVCLSDFAIKIRAYWSASSGEVTVVDDDEMEADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3V1</accession>
    <name>A0ABR1V3V1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012612</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662618.1">
        <property type="nucleotide sequence ID" value="XM_066816926.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049986"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF247">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="7">
        <location>
            <begin position="298"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="497" mass="54493" checksum="671CF195D28DBDC5" modified="2025-10-08" version="1">MSKSKKASKRKRDEQASAAVTKRKRDDPLTPLSPSPASDGAGRTTSATDAAPTSLTTVVSEEELELTVDTLRTLAEYPAIIKSKGCRDLRAAVYDFRQSCNTGTNTAIGDANLTAKISAALVDGKYTDALVNLAEMRIRNEAPKLGALCRWVRDLDVVSGLSLRKESDAGRPTIPRTNSQLELLRVLDSVLRVTGTMDKLPGILPSTPTEPIALQPFWDLRDTSRTPLAIRESVLDGSIFEGRPEGVKDKFRVLESTPGPERKPPNLHDAVLYLSEDDAVPLAAAGPTITYHHHPAVPNLSLMKDVLSPEECRSIIASTEAVGFLPDAPIRDDGSETSVLAHNVYWMIDQAFHDKLWSRVAPFLPSQVDGRKARSINRRFRVYRYVPGAEYRCHFDGAWPPSGINATTGKYMWDASPADAKQSSLFTFLVYLNDEFEGGETTFFTPSPVEGVVNAHPVRPTQGAIALFPTARARVLYSTKEQAYDPVPNVEYDVDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5A3</accession>
    <name>A0ABR1V5A3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_013124</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663130.1">
        <property type="nucleotide sequence ID" value="XM_066817438.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050498"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF1">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="9">
        <location>
            <begin position="398"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="320"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="641" mass="70871" checksum="0C64AA1A6B220DC0" modified="2025-10-08" version="1">MEKITDKIAALPADACYSSLEFFPPKTAMGFSNLRDRLDRMARALRPLFVNVTWGAGGSTSGKSLELAEICQRELNLTTCLHLTCTNMSRKMIDQTLEDAKVLGIRNILALRGDPPRADEYEDPNRDPEDAIDANFVWAIDLVRYIRKNHGDYFCIGVAAYPEGHADESHPLGQSLEHDLAYLVDKTLAGADFIMTQLFFDVDAYDKFERTLREHPSGAFKTIPLIPGLMPIQSYQMIKRTTKLSHASIPDTIMARLDAVKQDDEKVKNVGVDIGFHFYTLNLEKAVSFILERTELIPLGTPGEEEEAVADDLLPNIPALTVNGGSSTPQDSLAPPAHDHSRRQSSIGSDPRNRVIVMGRTPSHPEYETTAADASIPVEPINTRANTLAISEGEGVLGREATWDDYPNGRWGDARSPAYGEIDGYGPSLHVTNAQAISFWGHPTKAEDISNLFVKHLKGELAAIPWSEEEFNAETGTISQPLLELNSKGWWTVASQPAVNGLRSSDPTFGWGPHQGFVFQKAFSSEVKDSVCFFAANANGDFFSSDETGGLSGEAVEASTNAVTWGVFPGKEIVTPTIIEEVSFRAWCEEAYGIWGEWAKVYGKGTESSKLLERTKRDSWLVNIIHHDYMEKDALWDLLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5Z2</accession>
    <name>A0ABR1V5Z2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663382.1">
        <property type="nucleotide sequence ID" value="XM_066817690.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050750"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF289">
        <property type="entry name" value="GLYCINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="9"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="345" mass="37070" checksum="5D9337C6304D1EFC" modified="2025-10-08" version="1">MAFQPPSNVVVVGGGIVGASLAWHLAHETNVTVVAEHPGGVATPNSFAWVNAAYDNPKFYYDFRVRSMKHWAEIAEAVPGGLPLHWGGSVTWSMPPDELEKYEKQHQAWGYDIVRVNRTEIGEIEPGFELESVPEWGLFAGGEGTLEASVAAQQLLDHAVEYMGAKVIVNTVEGFAKSDAAEDGSTRVTGVITKDGKQILGDHVVLAGGLGSVPLLATEEIKLPVNGRQGMLVNSKPVAEKLLNTLINSDQLHVRQTVDEGRIRAGADYTGGDPGDNPQEDADKLFEKVKDVLVGGDDLEYDYYTIGTRPDPEDGIPILGNTGLEGSRLLSCTPESPMPLSWATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V648</accession>
    <name>A0ABR1V648_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HET-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663406.1">
        <property type="nucleotide sequence ID" value="XM_066817714.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050774"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF9">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="176"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="531" mass="60058" checksum="81F9605988E02D97" modified="2025-10-08" version="1">MPRPCQLCHGLQPNSGTSRLFLECKPDDLLQSANLGCESCGFLLRGLQAKEDSSWSLKDVSTVYGYGFRSEHDTLTLEIYFVQERPKVVLEFFVTDFTKPLQCEAIRPRASMNGHPMSARALNWVISKLQTCNDEHACYGQAKTPLPRRILALDASHRTVSVKVVEKDGSTAREKYAALSHCWGQGLRCTLTKANLEDMKAGVPWKELPKTFQDAIRFCLRLDLHYLWIDSLCIIQDDPGDWQVESAKMADIYQNSYITLAATAAASGDIGMFPRKSRWSKEPKVSFTDSSGSISWIGVRHRLSHWTFPMSTKSMRENPLLTRGWAFQERLLSPRVLHFCNEELVWECRSITTCECGSMPVLPSIKQQFAVDANNISLANDGSIAPKWNTDPTVHPSYQSKDLSALKCAETAWIRIVEQYSSLSLTRGTDRLPALSGLVARMADILGPGSYKAGLWAPSIRRHLTWRVDTISPGHRRPRYRWPTWSWASVDAKVTFWEEKDMRSPIGPLAMMPQRQWSPAGRAMKEWKPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6S9</accession>
    <name>A0ABR1V6S9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS multidrug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013369</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663375.1">
        <property type="nucleotide sequence ID" value="XM_066817683.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050743"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="84"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="525" mass="58427" checksum="E93D9F69B370CFFE" modified="2025-10-08" version="1">MDREPFQSSSSALEMQAVRYTPGSSTKAPTEEDLTQPHTRPKDEDGSVMQGEQLPVQDPNLVDWDGADDPKNPQNWSWKRKLVTTVVLSLCTFSVSFGSSILASAIAVLSTEFHVSPTVTTLNVTLYVLGFAAGPWIWGPASEYIGRYWPFVVGYVGFICFTVGVATAQNLHTIMICRFMQGAWGIATVTVTPGVLVDLWDIRTRALATIAWSATIVIGPTMGPIIGSFTVKNESLGWRWTMWFTLIISASFFILVLICFEETWGPVILQKKAKRLRYETKNWALHSKRDEAPVDTMALLWKYGLKPWQMIMYEPILVAICLYNSLIYGVIYLTFEAYPYTFGTVRQWEDGVSSLPFLSLLVGYLGAAIIQTFFHLQIIDKKLAKGIRPTPEDQLPTMILGSFILTIGLFWFAWTSSPNITWVPQVLAGPFIGCGINMVFVPCLNYLIECYLVDANSALAANTIIRSAVAAAFPLFASPMFANLGVAWATSILGFLCVAFIPAPIVFYVYGKKIRGWSKFAFTMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7M0</accession>
    <name>A0ABR1V7M0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013684</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663690.1">
        <property type="nucleotide sequence ID" value="XM_066817998.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051058"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="104" mass="11479" checksum="09DCF34C3744610D" modified="2025-10-08" version="1">MKSRDEHQKLTLALAPLTQPGYGTTCWSPHGGRPAKIKSTRLFVCSPRRGGPRFADAAVRDFRHDKSAFSDQDPYRRVLQGTLVRHHHDALGGQVTDSSGNRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7Q6</accession>
    <name>A0ABR1V7Q6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Rad8 and Rdh54p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_013940</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663946.1">
        <property type="nucleotide sequence ID" value="XM_066818254.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051314"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18070">
        <property type="entry name" value="DEXQc_SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052583">
        <property type="entry name" value="ATP-helicase/E3_Ub-Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059033">
        <property type="entry name" value="C144_05_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26021">
        <property type="entry name" value="Ferritin_C144_05"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="343"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="1123"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="1232"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="746"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1182"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="752"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8067193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1468" mass="165626" checksum="83C1D259C6E59F2E" modified="2025-10-08" version="1">MGRPRVQARSAGAKATTVVDYAQLNEPFPVALLDLLSSLPTSTTDAADGDSLDLQAEEIPERPRKRARHSPPILPDAVVVAEETFRLSRPSRPQHLKAQPRLAFSRPGASHHVKLHCLFAKDDAGDAIPKELTISGQEGARRRIKSTLTLPPDVSQAVATILKVVSSSRNEEDAEGGLLVDFDVEFRRGHTSGLDTISLRLRLKWNPTSNFYAGLRNSAQRTLSREVQTQFFPPDLLGDSNAGSLSAQAFYDAACIPSKDYTDLLSTDVLGLEAKLYPFQRRALQWLLHREGVVWNGTYLEPSQDHATSDLPLSFDKLTDSTGRSYFSSTLYQVVTRDIAPFRQLETAPKGGILSEEMGLGKTVETIALILMHRRPACPPKIVDPYSGQQVRPTGATLIVTPATLKNQWLSEVNKHAPGLRVMFYDGIKRYKGKGEELLKELAEHDVVITTYNVLQAEIHFAEEPPKRSMRHARTYPRPKSPLVQLSWWRVCLDEAQQIESGVSAAAKVARVIPRINAWGVTGTPVKDNVKDLWGLLLFLRYEPFASYPWAWEGLTTTHQHLFAPLFNRIALRHTKRAVRDELVLPHQKRYVLTIPFTAVEEQHYRSEFQAWARNCGLDLEGAPIKEDWDPEDPATLALLRSALASLRQTVLHPELGPGRIRGTAQRDKPLRTIEEVLDAMIEQSEQSIRTDQRQLMSSKLRRGQLLENSPRVKEALSIWEEVLGEIRVIVAECREQFEAELESAKAAGFDGADEDESGSEEFEGEKVPPRLGQARRRLQLALGLEHKAAFFIANANYQIKTNEELTEPESDDFKEYEKLEVQYYETAKEIRKEMLQEAHDKAAKHMTKLSEDAATQSFVEMPEFQFIVHKGLESRRVLENLEELGGVLDEQANLIDEWREQVIQILVRPLVDEDGEAEITGEEYEDSTKIQDDLMVYTHVLRAVIADRQDILTGLVNERVKHETTVAERLAKDGEGPNPEMLLELLKSRMDIKPPTPEWLRHDVTNGSQRAQVELEIVQEQLKLAQDQIGAQTKGANGLEKELDRFTDAMNARVEYYKQLQQISDTVAPWERGENEDDDALFNGLLREEAAIKHKIVDAQSKHRYLLHLKEAGQRSQGPRFCVICQSTFTLGVLTVCGHEFCKECMMLWYRAHHNCPVCKKVLNASMLHDISLRPESKLKIHSEQHPSAPDGNSPHKTRKPGIYSRFSEEKLQEIRQVDLSGPSFATKIDTLIRHLMWLRQEDPGAKSIIFSQFKGFLEVLGRAFDYHRIGYSSFDTKDGITRFKEDPGIECFFMDARAHASGLNLVNASHVFLCEPLLNTALELQAIARVDRIGQEHETTVWLYLVEGTVEESIYNLSVQRRMEHIGQAQTDRKGKSKEATPDVSDLNLEAANSMELQQAALSKLMSKDKQLGEVVDQNDLWECLFGHVAQKAAEATSAAQDERFENPAIMRFLAGEAAQARDRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V864</accession>
    <name>A0ABR1V864_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664111.1">
        <property type="nucleotide sequence ID" value="XM_066818419.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051479"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="24"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="385" mass="44240" checksum="DF778F311F2EF340" modified="2025-10-08" version="1">MSPAYPTSLFEAATISAMPRDNAFHFFPKVPTELRRLIWTICLQQQRIITIKIVPDTGSDDGYFVEAQRSYRHSKILRVCREARTAALEFFSLRIPCANLDARVPLYFNPELDVLYVDQEKYDGLGWFVDLLPKLATYDSRGVGVLNLATNRRVLSPMSDLDRELSKLPSPKKAAFTQTASRLRRLWVVVLENSNTRAMGGGLSWLDTTVHHNRAVPVFPLLQTFTRLPADPRPIERDLRNIGTFYHPQGLVDGWRQLEKELGISRAKGQSPLELQVLLAVDATNSSEYRKPIVDRASAERFVENEERWFREDVCTMFDVPVPYWGNYLDKEEWEGLRQSLPDAVGFWLFPADAFGHFPKNGTTPIKRVRDLRDHPPELCVFDMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8M1</accession>
    <name>A0ABR1V8M1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Asl1-like glycosyl hydrolase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663162.1">
        <property type="nucleotide sequence ID" value="XM_066817470.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050530"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF3">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="2">
        <location>
            <begin position="71"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="33498" checksum="84270A821A18EB4F" modified="2025-10-08" version="1">MDNNDGSNKAQSKRGLAYQQGAHKADNNLLFSPESPVAWYYTWSLWPAPEVNDTTSAAVEFLPLLHSPDDPDGDTGSGGSAVEPEDAAKAYIDRIAPLRSGGDGGRTWNISHPSVTGSPRGLDWLRRFNESCWDLDRDQGCPADFVAVHWYGEYQGLAGWLDTLRDFYKKTPSSSSELKFWITEMALPQQDDEATLRMMNETLPYLDGLDYVDGYAWFGAFRKGEKANEWTGDAVSLFDDEGGLTELGSLYLSPGSGGDGKNGDSGGGGFEPGTKGPPGNDGDEEGAAASLPVASRWAVGLAGVLAVGLVAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8Z5</accession>
    <name>A0ABR1V8Z5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664125.1">
        <property type="nucleotide sequence ID" value="XM_066818433.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051493"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8067372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="104" mass="11849" checksum="C90026C81D7CCFD5" modified="2025-10-08" version="1">MVEIIPSFVSLRALLSHYRRPAVRRQHPEPEVAHVPRPQGQALLNGRSPHQFINTTPIVEFAAYCGDEANRKEYLIIKSGKKTSYMGSVNSNTNRGDHRVLYTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9Z7</accession>
    <name>A0ABR1V9Z7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase accessory subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663536.1">
        <property type="nucleotide sequence ID" value="XM_066817844.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050904"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03043">
        <property type="entry name" value="QTRT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028592">
        <property type="entry name" value="QTRTD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="6">
        <location>
            <begin position="26"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="487" mass="53417" checksum="2BDE42381FCA11E0" modified="2025-10-08" version="1">MSAPAVNGDDMSFKIIQPALEHGLAARVGRLATANRTPLETPTFVGVTSRGAIPHLTPDVISKHTDIRAAYMALEDFIEKSSKRKSPAIFSLPKDGCRPLHAYTATPSTTYTILAPRRTPAVVAQNGNGPKHISVLTSTGFERVTCENFCTAVEQIMPDIVVPPADLTFSSTTPGAKRQAYMVKRTQEWLDEFFTHLDPEKTLKPSDIQVFAPLLPLSYPIQWEYLKHLAEEHAAKLNGLTLYDVKILHDLKNHPQLLDLPRMSMESPESPQQILRQVRLGVDIFASPHVNNVSDAGIALNFSFAPSSTGSSGLQPLGIDMSSEEHQTSVKPFMEGCGCYACTKHHRAYLQHLMNAREMLGWTLLQIHNHHVMSEFFRQIRQAIADGTFEEKATQFNKYYESELPLGTGVRPRARGYHFKPEAAQPKINKAPWNRLEGEGTPDQVAAAEAAGLAVTGPAAGGSETPLVPEADAAALAKEGFAKIERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VA96</accession>
    <name>A0ABR1VA96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Small acidic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013907</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663913.1">
        <property type="nucleotide sequence ID" value="XM_066818221.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051281"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026714">
        <property type="entry name" value="SMAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028124">
        <property type="entry name" value="SMAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22175:SF0">
        <property type="entry name" value="SMALL ACIDIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22175">
        <property type="entry name" value="SMALL ACIDIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15477">
        <property type="entry name" value="SMAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small acidic protein-like" evidence="4">
        <location>
            <begin position="291"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8067160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="360" mass="40225" checksum="8CDD4C30CCB4A371" modified="2025-10-08" version="1">MEKGEAGWDKGQDHQEILAQAERKEKRAKRKEELRLQRAAERKEKRQLKSEAKKARKANVGRAGKWNEERRAADKLKKQANKKYKDERRFNRLLLRAEKLEAQAKKLMKDAQIARARHEIISKQKEAEAAKTKEELKGDNFIALEGGEDDDSSSSSSDSSSDSSSDSEAEDVEMKDPEPVAEKPAKKAKKSKKDKEEPAAAAPAEVEVTAEEPKVEKKDKKEKKDNKEKKRKRDTEGDATAEAESTEKADEADEAPKEKKPKKKSKKSEEYVSESAPTNVEGAKADGAEKWDVQALEGDEARKNKFLRLLGGKKAGLTAQGGATSSKRNINSITSNLERQFEAGMRMKNENQGHRKGLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHQ5</accession>
    <name>A0ABR1VHQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664485.1">
        <property type="nucleotide sequence ID" value="XM_066815195.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048255"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="68" mass="7677" checksum="DDA277B01E3981E1" modified="2025-10-08" version="1">MGSQSDKQFRGLLIRTNIALLQRQVREKSNWYNTPRVVIRKRSGKVIVSRLGTPASYAADAGFEIVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHY1</accession>
    <name>A0ABR1VHY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011027</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664632.1">
        <property type="nucleotide sequence ID" value="XM_066815342.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048402"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="147" mass="16475" checksum="C92E9B73864BD7E0" modified="2025-10-08" version="1">MAWQIFLNEFACGHFEIRRSVETKSVELPNSGPAVKMNLQVLSGRCKKCPPRDCTGIVVCYSCGHPMAAGVSTWRCQQQQPGEDKDKNHAHQNPKYLAVPLPEPCDRDSCDKKIRLRAIQPLSVSTVRGLEAKDYSRWAPVIPPRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIE3</accession>
    <name>A0ABR1VIE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="3">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011209</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664814.1">
        <property type="nucleotide sequence ID" value="XM_066815524.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048584"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="379"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="460"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="474"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8071006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="576" mass="62557" checksum="3E35945D4F545E1C" modified="2025-10-08" version="1" fragment="single">SIKDVSKSMARDLMSLYTGDKPGGTPGLLPQPYYFSGKGWEAGALMGAMVDYWYYTGDTTYNKVTSEGLLFQVGPNNDYMPPNQTLTEGNDDQGFWGMAVMSAAEYNFPNPPAGQPGWLALAQAVFNTQAARWDPQHCNGGLRWQIFTWNNGFDYKNSISQACFFNIAARLALYTGNATYADWAVKTWDWMVGVKFIDEHYYVYDGAHTTDNCTGIVPYQFSYNPGAFLLGAAAMYAYTNNLKQTDESALWHERVDGLLNGTDVFFHSMTGTSPKIMFEVACEPVNLCNVDQQSFKAYLSRWMAATTKWAPWTFDRIKPLLQNSAVAAAKQCTGGYNGRMCGIRWVNNSDGVWDGTMGVGQQMSAMEVVLANMIEKAQPPVTNSTGGTSEGNAGAGGSDIGRTDPHGTFATSPITTGDRVGAAFCTAAILGALVAACLWMMNDETKSAHENWQDVRSAFAGGGGGRAAAKLSRKSRDAGYDEKGKGVADYSPNASVEQTSRPPYGIFEVGPPPTTRGSPLQSPRRAVRGGGASQYGPAFSAQDEGVPRVGARSQDERGSKRFLQKKRARYIDSEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIM4</accession>
    <name>A0ABR1VIM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_011287</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664892.1">
        <property type="nucleotide sequence ID" value="XM_066815602.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048662"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF13">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="12">
        <location>
            <begin position="18"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8071084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="245" mass="25635" checksum="A983EBEDDB3CD86D" modified="2025-10-08" version="1">MKLSLATAVAFGLSVDAHAIMQKIKVNGQDQGSLNGLRAPNTNNPMQDVSSSSLACGVPGYTSNTVIPVKAGDSIEGWYQHIIGGPQGANDPDNPIASSHKGPVTAWLAKVDNAASASATSARWFKIWEDTFNTGSRKWGVDNLIANNGWVKFKLPTCIPSGDYLLRIETLALHSAYSQGGAQFYTSCAQIRVSGGGSKTPGSTVSFPGAYAANDPSVVIQIYGSSGQPDNDGKPYSHGPAPFTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ65</accession>
    <name>A0ABR1VJ65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665087.1">
        <property type="nucleotide sequence ID" value="XM_066815797.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048857"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="100" mass="10696" checksum="E80DAD29F900F0CD" modified="2025-10-08" version="1">MGILAPQIAFVLTHPRVHRVWYDIADPAEKPAGVLVVKAKAQKPVEALKHHAAVEKAPSQRSTAALTPDEQAKSLAQTPLAVTEVEDLASKLVLSKFALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKX5</accession>
    <name>A0ABR1VKX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664402.1">
        <property type="nucleotide sequence ID" value="XM_066815112.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048172"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25499">
        <property type="entry name" value="Beta-prop_pof12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="13"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="596" mass="65220" checksum="0DA6615ACB65702E" modified="2025-10-08" version="1">MPEPQTTSARPRHDNLSPLSDELLIRILTCLPLPSLLNVAPVSRRFHRLAEDSQLWKRLYYNRFVLPRAMRIPGFRNGSAREGKLHYSSRRAIWADGRRGGWVDMRSNSSDNNNGGRVDRPSTSRDWKGQYKLRHNWSKGKAAVEELHVGDHIAAVGTGEEIATTARPMLVKISEGVAITADLSSGLRAWDLRTKELVAQATFLESGSTSPAAPSCLAVDDQDLHSRVLNVAVGFEDGSFGVWKLDIGKHELIRKYRHEKSTNGELVGIAYSHPYLLKATESVLISLYTFEVPEDPRSATIPAQDRPRAESINIPTEMDSQTEDEACAAGSDPKIPQMTNAPSGSLQAPVLLTSLKSHTSRAPLALSIRKTASTTIASIAYTFSTLQGWSLGIQDLHLRASASKTKTTPDITTTRIAYSPPVRSSPSQQVPSPPSSPAQATAHAYRTHAADDGPTNICYNHPYLLATLPDNTLILHLCTSNATSLSVSPGIRLWGHTSGISDAEITSRGKAVSVSCRGEEIRVWELEGRAEARSIEVRPNVPAAKAKADAESDESNSNTLAAFDEKRNWVGFDDEMVIVLKESSQGRESLMVYDFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VMP9</accession>
    <name>A0ABR1VMP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664926.1">
        <property type="nucleotide sequence ID" value="XM_066815636.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048696"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="81" mass="9568" checksum="24F643A6E6FF331D" modified="2025-10-08" version="1">MGKYNTTAYLIYRRKSREPTRAGGGYIGKRFLLCRLIIFQCQDVYSLQDRNGHWRSGTARARRRQSTMAIQGREKKKREVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT06</accession>
    <name>A0ABR1VT06_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">26S proteasome non-ATPase regulatory subunit 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009064</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665341.1">
        <property type="nucleotide sequence ID" value="XM_066813379.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046439"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040896">
        <property type="entry name" value="RPN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18098">
        <property type="entry name" value="RPN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSMD12/CSN4-like N-terminal" evidence="4">
        <location>
            <begin position="33"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="PSMD12/CSN4-like N-terminal" evidence="4">
        <location>
            <begin position="236"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="PCI" evidence="2">
        <location>
            <begin position="352"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome regulatory subunit RPN5 C-terminal" evidence="3">
        <location>
            <begin position="415"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="468" mass="53657" checksum="125F690B958B85E6" modified="2025-10-08" version="1">MADAAFKPEKDFSKEADKQISEAEKLAKNDVSSAIEKLTVFEKQTRQASDLASTSRVLITICTICKEAGNWNLLNDQVLILSKKHGQLKQAITKMVQTVMDFLDSTPNLDTKLSVIETLRTVTEGKIFVEVERARVTRILSDIKKQQGDLKAAMDILCELQVETFGSMERREKTEFILAQVALCIENNDWTQASILGRKISTRYLSRKPKKTPEQIEKEKKDREEKIKRGEDVPEVKEDDTTDLKLAYYEQQIILAKHDDKYLDVCKHYRQVLDTEAVENDPSKLQPQHDLLQRVFRDARNTQVPTDAQLLKLFTVPELMRWPEVAKMFGPHLCSTDVFDPKPNESGDDKAHQRWLDLRKRVIEHNVRVRLTQLLDLTVEETEKYISELVCSKTVYARIDRPAQIVDFAKPRDTDDVLNEWSHNMKSLLGLLERVDHLITKEEMMARIQPGAQGGKGGKDKKGKKAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUN6</accession>
    <name>A0ABR1VUN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endo-beta-1-6-galactanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665910.1">
        <property type="nucleotide sequence ID" value="XM_066813948.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047008"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039514">
        <property type="entry name" value="6GAL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039743">
        <property type="entry name" value="6GAL/EXGAL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42767">
        <property type="entry name" value="ENDO-BETA-1,6-GALACTANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42767:SF1">
        <property type="entry name" value="ENDO-BETA-1,6-GALACTANASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14587">
        <property type="entry name" value="Glyco_hydr_30_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045365974" evidence="1">
        <location>
            <begin position="22"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Endo-beta-1,6-galactanase-like" evidence="2">
        <location>
            <begin position="27"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="484" mass="52711" checksum="12F7A78228F337BF" modified="2025-10-08" version="1">MSRRCLSSLLLAANLCGRGAADTTATINPSINWGTWEGWGTSLAWWAASFGDRDDLADLFFSTKSVNFGGKTVPGLGFNIARYNAGACSKNSVNGESMVVSPKMIASRQIDGFWTDWTSADPASSSWNWNVDANQRSMLTKARDRGADVFELFSNSPMWWMCSNHNPSGSDNGGSDNLQSWNYQQFAVYMAEVAKHASDNWNIKFQSVEPFNEPMASWWNGKSGTQEGCHFGTSTQVTLIKNLRTELDNRDLSSAVIAASDENSYDQAITTWNALAKAGVAGSVARVNVHGYQYGGGKRDVLYSTVQGAGKKLWNSEYGKADDTGSDLASNLILDFRWLHPTAWVYWQVIDGGGWGLVDGNNDAKTLGAVSQKYYVLAQYSRHIKPGMQILDGGNDSTVVAYDAGAKKLVVVAVNWGNAQNLVFDLSKFKTPGTDGSPVPRWSTQIGSGEQYVAHSDITLKGGKFQTSFSKNQVQTFEVSGVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVH0</accession>
    <name>A0ABR1VVH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009902</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666179.1">
        <property type="nucleotide sequence ID" value="XM_066814217.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047277"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF123">
        <property type="entry name" value="GMC OXIDOREDUCTASE (AFU_ORTHOLOGUE AFUA_2G01770)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="147"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="469"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8075239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="573" mass="60674" checksum="9CCFD57FE041C77C" modified="2025-10-08" version="1">MSDLADVDYIVVGGGLTGCVVASRLSRGDKDGKKPQVALLEAGSDPAGNPAAGGFLSGLSLLGGDYDYSFQTEPVPGTADRVHTLNFGKVLGGGSILNLGGWLRADAADYDDWAEMPWLRKTEYFFSGNPDEAAVTVGDDQKLDAEQHGFNGPMHVSPVSVGESGIRKYPLREPVRGRLGRAGRALQPPPEERPQHRPDRNVRERPRRHAAAGPVRVPLDGGANAVRVYTNTLVRRVIFSEDDGDGDVAATGVELADGRKIAARKEVILCAGALRTPQLLMLSGIGPSATLEAHGIPVVRDAPDVGQNLHDHFALYLAYRLRDPSLGYALGNAAFQEKQDPKFSNSPLPWDWEKHHQAAKTPPESDADARNTWEVITMYVPPIPGIPIDGSHIATSTMLLRPTSRGAVTIRSGDPGDAPRIQPNHLSTALDRDTLVHAVQTTLKAMLETSAMKGIVACESPPSFVGKIGAAAAGEGDGPDGNDSGAGLVPLSADTSPEALEDRIRRTGLAHAHPGGTAAMGKVVDTEGKVLGVRGLRVADASIVPIPLGGHPQATLYAMTEQLTSFILRDYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW57</accession>
    <name>A0ABR1VW57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_010143</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666420.1">
        <property type="nucleotide sequence ID" value="XM_066814458.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047518"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047207376" evidence="11">
        <location>
            <begin position="29"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="825"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="860"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="902"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="938"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="968"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1054"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="85"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="373"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="665"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="665"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="686"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8075480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1080" mass="118277" checksum="D63CD8978C68F24E" modified="2025-10-08" version="1">MSPPGILKTALALGFLLSSAIAPSLVMAQTNYTQVDMMRAQLALMGGRSDDCPPCFNCLLPAYTCGQYAPCKEYNGKCDCPPGFGGDDCIEPTCGSLARGKDRPMRQGDTCECDEGWTGINCNICTENKACNALMETDDDGGVCYQTGDVVKQNYQMCDITNAKILSMLEGKVPQATFSCQKEDGLCDFQFWIDRVESFYCHLTECEAHADLNEGTNSTYYKCASAQCSCVPGRMLCGQQGSIDLTDMLKEEIHGPASFSCEQKKNGDNQCKFKEPALDQLTQDVFGDPSIELNCRSGECLHITEVPGYERPVKKINTPLIAGVIAGCSLFLVAVIFGVWYLSRRSFKYSQISLDDSDDEAMKLMADHKPASLYFENVAYDLNGKRILDNVQGVAHPGEIMAIMGASGAGKTTFLDILARKNKRGEVSGDFYVNGEKVTDTDYKNVIGFVDQEDTMLPTLTVHETILISALLRLPAGMGRAAKEQRVWEVEKQLGIYHIRDSLIGSEEGKGRGISGGEKRRVGIACELVTSPSILFLDEPTSGLDAYNAYNVVECLVTLAKTYKRTVIFTIHQPRSNIVALFDRLMLLAKGKTVYSGSFAHCQEYFDSIGYACPPGFNIADYLVDLTMHAGISEPYDDGTLNADSASVGPSSTTAVKSIASISGNSTAGDSISTDPSSSRPRNKRRDSVKQKQDRDLYTRRKNTIDTAASSDVEEEIGAYKLRAQPPPQIHVEEAHDLPPSASAGTDLDVLFQAYFESDIAANTHDEIHQAIENAQAVNGQNGYSPEGPNIFTSAIGKGYARPSYLRQFVILSGRTWKNLYRNPLLMLMHYAVAILLAVLSGFLFYGLTDDIPGFQNRLGLFFFLLALFGFSTLTTLNVFASERLLIVRERANGYYTPITYFAAKVLFDIVPLRIIPPILMGIIIYPMTGLVADAEHFFTFILILVLFNLAAAAICLFIGIVCKDGSVANLVGSLVMLFSLLFAGLLLNHDAIPASALWLQSLSIFHYGFEGLIVNEVVKLNLVDQKYGLDIRVPGAVILSSFGFNNGALWWDVINLGIFAGVFVILAYVAMHLLLVEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWU0</accession>
    <name>A0ABR1VWU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">26S proteasome regulatory subunit RPN2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010398</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the proteasome subunit S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666675.1">
        <property type="nucleotide sequence ID" value="XM_066814713.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047773"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016642">
        <property type="entry name" value="26S_Psome_Rpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048570">
        <property type="entry name" value="PSMD1_RPN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040623">
        <property type="entry name" value="RPN2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18004">
        <property type="entry name" value="RPN2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21505">
        <property type="entry name" value="RPN2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015947">
        <property type="entry name" value="26S_Psome_Rpn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="7">
        <location>
            <begin position="6"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="7">
        <location>
            <begin position="181"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome regulatory subunit RPN2 C-terminal" evidence="6">
        <location>
            <begin position="856"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="149"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="352"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="908"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1033"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="916"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1090"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1108"/>
            <end position="1118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1118" mass="121862" checksum="52AE443DA8A79CAC" modified="2025-10-08" version="1">MPGLVTATGVLGFLADEEPELKVFALQTLNDDIDTVWTEVAGALGQIEALYEDDSFPERKLAALVLSKVYYHLQAYDESMFFALAAGDLFKLDNPGEFEETIISKCVDHYIAAKNENHSVLSQKDSEDKSLPALATAFSGTNDGNNASALISPTTPFSQSTLPSNPPKKQHRSSSIALSQNELNTRRAIDAVIERLYESCLKEGRYKQVVGIAVEAKRLDVVSKVIQRADSDYKKSKGKAADEEALGPAEELMDYCLTICLDIVQERAFRDDILQLVLEILTSGRAKDPDYFSIAKCIVYLNKDEQAGTVIHHLVKEGTPHSTAIAYQFAFDLYDNGTQEFLGKVIAPLPTGESASKTEGEATERDSLLADTDNSSAEPDEKKTEVYRNIRSILDGTKTIKLNVEFLYRNNHTDLSILNKVRDSLEGRNSIFHTAVTFCNAFMNQGTTNDKFFRDNLEWLGKAVNWSKFTATAALGVIHRGNLSQSRKLLEPYLPRGAGGISGGSLYSQGGALYAYGLIHANHGADALDYLKTQFTAAEEEVIQHGGALGLGIAGMATGNEEIFDNLKTVLFADSALNGEAVGLSMGLIMLGTGNVKALEDMVTYAHETTHEKSVRGLALGMALIMYGRQEQADVMIEGLLNDPDPTLRYGGIMTVAMAYCGTGSNKAIRKLLHIAVSDVNDDVRRIAVMSLGFILFRKPGSVPRMVELLSESYNPHVRYGSAMALGISCAGTGLDEAIDLLEPMMKDPTDFVRQGALIALSMIMMQQNEVMNPKAATIRKTLKKVVGDRHEDAMTKFGAALALGIIDAGGRNCTIGLQTQTGNLNMAGIVGMAVFTQYWYWFPFTHFLSLAFTPTSIIALDHDLDIIDLKFHCSTKPSLFDYPPEQEVKTEEGPALIATAILSTTAQAKRRAQKKERAQRRESMDIDDPKKPSPEKMDVDEPKKPEDAKKDEEAVGDKETSAPPADSKKKPGYEVDNMTRVLPAQLKYISPIKGRYWPVKLVRPGPLPTGGPILLHDTQPDQAKSLIEEKLKKVSTDKAPVPNAGGAGGNRSARTELENRLLQSFGVNPPVTPGGAGGAAAAAGVLTAVDEDQEGDEEAQPPRDFEYFTEGEDEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWX5</accession>
    <name>A0ABR1VWX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nad dependent epimerase dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666292.1">
        <property type="nucleotide sequence ID" value="XM_066814330.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047390"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF3">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="253" mass="27968" checksum="65343BEDA795DD4F" modified="2025-10-08" version="1">MGGVPSKPGDASTKLEVIGAGYSRTGTASMQIALEMLMQGPVQHGGGHLLWREDSFPKRWVQAYEARQAGDKETVLKLVRQQVSGYVGCTDMPNVDFLPELLELFPDVKVVLVTRDPAKWWKSIGVNLSYASPWWLRCSRPRCRPSGGSQALSTIGATRRWISSPRPTGPARRWDHSIVPPEQLLVMDIKEGWAPLCKFLRKPIPDEPFPQVNDAETADKIGMSIFAKLALTWVGLLGTVGMGAYGLMRLAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX83</accession>
    <name>A0ABR1VX83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665388.1">
        <property type="nucleotide sequence ID" value="XM_066813426.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046486"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01010">
        <property type="entry name" value="CRISP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="143"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="33160" checksum="5396D89069202A91" modified="2025-10-08" version="1">MKYSIFITGASAAFALAGPVNKRDMVTKVDVVEVWDTVTVTAGDATPTPAPAPVPTQPPPDVVIVTVTADEPQPQPKTQAPPPPPPAPTTAPAPAPQEPDVVIVTVSAGLEAPAPLPTVKAPEPVTIEPTPNRPITANKLSVAAVNSHNQHRSNHSAPEAQWDDRIAGYAANTAASCKYAHDMKQGDADYGQNIAMWGLSSGAEKLGDVGAINMAITDMWYNGELNLFLPSYYGEASPDMTNFEKWGHFSQLVWKESTKVGCQAQFCPKGTMNDIMDTWFMVCNYYPAGNMGGGYAKNVLRPLGKSNIVAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXN3</accession>
    <name>A0ABR1VXN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009231</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665508.1">
        <property type="nucleotide sequence ID" value="XM_066813546.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046606"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="9"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8074568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="198" mass="22313" checksum="F73ED84AD278EDF1" modified="2025-10-08" version="1">MSSASLGPCIVCEKQDSPRCLRCNSAFYCSKTCQRIDWPVHGLLCGSFATFNASSRPTEEHFRTIVFLPNNKEPQFRWIHCKWLPISVSRHSRAYTFLVDGSARNKSVASIIATQQGDYHDWRGPITAYGKLGPEPSRLCRDLDMNDFRHIADYFLSYGHRLPQLTPPAQQVAAERVVFSMTILAVIVVAAVAILLCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYH1</accession>
    <name>A0ABR1VYH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">U3-containing 90S pre-ribosomal complex subunit-domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665838.1">
        <property type="nucleotide sequence ID" value="XM_066813876.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046936"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032704">
        <property type="entry name" value="Cms1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24030">
        <property type="entry name" value="PROTEIN CMSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24030:SF0">
        <property type="entry name" value="PROTEIN CMSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14617">
        <property type="entry name" value="CMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="260" mass="28906" checksum="11D3CA77A4B9DE01" modified="2025-10-08" version="1">MSNNEVTVAKSEAMASKAKSKKRARTDEGGARKKRKAGFQQDESLLDTEAGVNQAIAAMDPQLLADYLAQKTSRFGSDLSPVELADLYISPLSIEDTTSWQEPRNLEKLPEFLEKFTKEPEKLKKAPKLKGSPHTIIVSGAGLRAADVVRSVRKFSSKGNMVAKLFAKHIKLEEASKNLKEHRTGMAVGTPARLNDLVENGSLSLANLERLVVDASHIDQKKRGVLDMKDTLMPLVRWLARKEFKEKYGATEKPLQLLFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYQ9</accession>
    <name>A0ABR1VYQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Isovaleryl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009712</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665989.1">
        <property type="nucleotide sequence ID" value="XM_066814027.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047087"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF18">
        <property type="entry name" value="ISOVALERYL-COENZYME A DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="9">
        <location>
            <begin position="53"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="8">
        <location>
            <begin position="167"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="7">
        <location>
            <begin position="274"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="432" mass="46362" checksum="46D241F8D1A94265" modified="2025-10-08" version="1">MRSFRTLARPAGRALSSSRSKQFAPAAIRISVRHASSSSKHPEGFEAPSPADLAELRERVQEFTRREIPEEVAAHTDQSNAFPNEMWPKLGEAGFLGMTADEAYGGLAMGYQAHCVVMEEMSRASGSIGLSYAAHSQLCVNQISLNGSADQKQKYLPGLVAGTSVGALAMSESGAGSDVVSMRTTAKPVDGGYLLSGTKMWITNGPDADVIVVYAKTEPEKGSKGITAFLVDTKSEGFSCARKLDKMGMRGSNTGELAFSDVFVPSENVLGQVNGGVRVLMEGLDLERLVLSAGPLGIMQAALDVALPFTHQRKQFGSPIAHNQFVQGKLADMYTKMQASKAYTYNTARAVDEEGIIKTQDCAGAILYAAERATECTLDCIQLLGGMGYVEEMPASRLLRDAKLYEIGAGTSEIRRMVIGRAFNKEFAHFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZB5</accession>
    <name>A0ABR1VZB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphoribosyl-AMP cyclohydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_009861</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666138.1">
        <property type="nucleotide sequence ID" value="XM_066814176.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047236"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11546">
        <property type="entry name" value="NTP-PPase_His4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="entry name" value="Phosphoribosyl-AMP cyclohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42945">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42945:SF1">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN HIS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101386">
        <property type="entry name" value="all-alpha NTP pyrophosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="HisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosyl-AMP cyclohydrolase" evidence="12">
        <location>
            <begin position="205"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="366"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8075198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="416" mass="45527" checksum="164E73AA1F3E57D9" modified="2025-10-08" version="1">METTLPLPFLISVAVPPGLDSSEGLSRGEVSCLGCVFFDVTQQNLDKLLHYLDQHSSEFHTFFDVTAVESKDDIISLLDHGARKIFVQPERLAEFADFKGRVAPAVAKLSNVSVGTEYGILLKDFDHNKCDVAKFLEHSTAEKLPPTYIKPIQGTNFEQFVAVCSQISAIPILPSTGLTTNKDDQSKIFVSTMLSGAWISDRPDKLMPTTQTGVYQSRKRGLWYKGATSGDTQELVRVSLDCDNDALKFIIKQKGKFCHLNQFGCFGDLKGVSKLEQTLVSRKESAPQGSYTARLFSDEKLLRAKIMEEAEELCDAQTPEEIAFEAADLIYFALTKAVSKGVSLSDIERNLDAKSLKVKRRTGNAKGKWAEKEGITNETVEKAKEAAKDSTTPLTSAPAAGSPDCPGSGQNLNEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8H4</accession>
    <name>A0ABR1W8H4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 17">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="3 17">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_007601</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="17">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="3 17"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667258.1">
        <property type="nucleotide sequence ID" value="XM_066811916.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044976"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07856">
        <property type="entry name" value="STKc_Sty1_Hog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008352">
        <property type="entry name" value="MAPK_HOG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038783">
        <property type="entry name" value="MAPK_Sty1/HOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01773">
        <property type="entry name" value="P38MAPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0010">Activator</keyword>
    <keyword evidence="9 15 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 17 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 15 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="20"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8079783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="359" mass="41213" checksum="CB90F86F61958151" modified="2025-10-08" version="1">MAEFIRAQIFGTTFEITSRYSDLQPVGMGAFGLVCSAKDQLTGQNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENVISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDIEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVKSLPKRERQPLKNKFKNADPAAIDLLERMLVFDPKKRITATEALAHEYLAPYHDPSDEPVAEEKFDWSFNDADLPVDTWKIMMYSEILDYHNVESNNPPAVDPEQFNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8P3</accession>
    <name>A0ABR1W8P3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arf gtpase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007664</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667321.1">
        <property type="nucleotide sequence ID" value="XM_066811979.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045039"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08831">
        <property type="entry name" value="ArfGap_ArfGap2_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686:SF4">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="11"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="141"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="487" mass="51443" checksum="90644040B4D80DCB" modified="2025-10-08" version="1">MSALASKQQSQKLFEKLKSKQANKICFDCGAKNPTWTSVPLGIYLCLDCSSNHRNLGVHISFVRSTNLDQWQWDQLRVMKVGGNESATKYFRANGGSAALASKDPKTKYQSAAATKYKEELKKRAARDALEFPDEVVITEATDADDASTPASEPNDDFFSSWDKPSIKRPTPPISRTATPPVVGRTPSPFLNANANGKDISRSASPLSKTESGDAKPAASRITSSAALRKTTTGGAGPRKANVLGAKKTTKLGAKKVTGDVIDFDEAEKKAKEEAERIAKLGYDPEAEEAATKKPAAASKAEASNIASPAPASPATYGSGHSRQKSAAEVERLGMGFGRLGFGQVGGGKAAAAPAAKKNMGGFGSVGPVKAAVEDDSERYARNKFGTQKGISSDEFFGKGSFDPNAQAEAKTRLQGFEGASAISSNAYFGRPEDEEPADDYGDLETAAKDFVRKFGITAGDDLENLTSALGEGATRLQGAIRNYLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W925</accession>
    <name>A0ABR1W925_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl coA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007828</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ACBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667485.1">
        <property type="nucleotide sequence ID" value="XM_066812143.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045203"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF62">
        <property type="entry name" value="ACYL-COA BINDING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="3">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="104" mass="11325" checksum="939FA740DF47B08D" modified="2025-10-08" version="1">MVEQTEAFKKAVVDSKKLTTKPSNDHLLEMYALYKIGTGEDIKAAPAPGMFDIKGKAKAKAWQGKVDEGVTPELAQEQYVALIDKCKAEYGYDENKAPEAVGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W935</accession>
    <name>A0ABR1W935_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Plasma membrane channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007799</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667456.1">
        <property type="nucleotide sequence ID" value="XM_066812114.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045174"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="572"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="608"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="7">
        <location>
            <begin position="22"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="6">
        <location>
            <begin position="181"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="734" mass="83016" checksum="03D78E966CBD60FB" modified="2025-10-08" version="1">MASLRTLYAADGNPPALKTNMNVDFVINYRIPSDAPVEAEAGFTQLIEALTKAGLASEVRRGVDHTSVLVFVKVASEKYLKSRIYRERVQDWLYGVRIKTPEKDVDKIFQDEPVVDAERLRLVYLLLTNPKNEGGAGITPKTGQWKYVESIFPLHNHAFNRKWIKQWSSKYVLNEEDVDQIRNQFGEKVAFYFAFLQSYFSFMVFPAAFGFASWLILGQYSWLYALVNSLWSVVFFEYWKKKQEDLAVQWGVRGVSRIQLPRTEFQWDHEAADPVTGEAVKVYSTKKRLQTQLLQVPFALICLLILGALYLFCFSVEIFIGEIYNGPFKSYLTFLPTIILTGLVPTLSTILGNLAEQLTVAENYETHDAHDAALTQKIFVVNFITSYTPLFLSAFVYMPFGNLLVPYLDVFKVTAEKIASSDKLTTQNFQINPDRLRTQVIYFTVTAQIVNFALEAVVPIVKRKVFKKVKEVQTEFTHKNDKGDVVPADAPEEAAFLARVRNEAELDVYDVATDYREMVVQFGYLSLFSAIWPLAPVSFLVNNWVELRSDAMKIAISSKRPIPWRADSIGPWLNALGFLSWFGSLISSAIVFMFSGDSNGPGGEPSSITAWALLLTVLCAEHLYLAVQFAVRYGLKQMNSPGLHKERAERFQMRKSLLAETLDNDVENKPLPDIPTGEKITRAALEEEARQASIRGHGTPEEAFWQRQQGMDETISIGRSLISKMAAANKTAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9L1</accession>
    <name>A0ABR1W9L1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008002</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667659.1">
        <property type="nucleotide sequence ID" value="XM_066812317.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045377"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046184488" evidence="5">
        <location>
            <begin position="20"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="391"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="691" mass="74666" checksum="3C62870A04FAF8BD" modified="2025-10-08" version="1">MKFALPGALLCAGATLVTATNKEDIHFIYPRYPEQTRYVTLGPQLESAAPPANKTYEYIVVGAGPGGSPLAARLAMAGHSVLLIDAGGDHGNLREVKIPAMSIWSSERAELTWAYYTHHYEDEKMAKKDRKLTYRTRNGSLYSGLNPPEGAEMLGNYYPRVGGVGGCSQHNALISILPTNGDWNRIKELTGDDSWDAEKMRGYYKKLEKNEQPFPADADAHGYSGWLKTAVTPLSLAAQDFKILSVILGAAASAGVELNGPLAQLRKLAESLTGGVLNKLLPINYLTGMVDGLASLLLHDMNTNDPNRDSTPALVQMPLSMGAPSYERSSPRDLVYGVATAKNPDGSKKYKLDIATNTLVTKVNFDTTGEKPRATGVDYLCGGEPVILSAGTFNTPQILKLSGVGPADELEKFNIPVIKNLPGVGTNLQDRYELGVTAEVSSDFDLVAKCTYLADGDECYDQYMNNAGALKGPYTTGGLAVGYFMTTSQAEGEHDIWVGGLPAIFQGYFPGYSTHILTTTNKNHWTWLVLKAHTRNTAGTVNLTSANPRDTPKITFHNLFEGSTVEDANKDLQAVVEGMRWAVKAIDEIRPLDGSTFSQVWPPRSVTDDDAALRDWIAEEVWGHHASCSCPMGADGDPMAVLDSQFRVRGVEGLRVVDASAFPKIVGTFPVLSIYMMSEKAADVILAGLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9N0</accession>
    <name>A0ABR1W9N0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007945</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667602.1">
        <property type="nucleotide sequence ID" value="XM_066812260.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045320"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19146">
        <property type="entry name" value="AKR_AKR9A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="30"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="382" mass="42548" checksum="523B02B661126382" modified="2025-10-08" version="1">MAPLPMAPQPKSPLGRYRLLSPTASVRVSPLCLGAMNFGEAWKDFMGACDKQTVEQILDFFYSQGGNFIDTANNYQAEESETWLGEWMKKRGNREQMVIATKYTTCFRAGRGDSEILANFTGNGTKSLHTSVNASLRKLQTDYIDLLYVHWWDYSTSIPELMQGLNTLVSQGKVLYLGISDSPAWVVSKANQYARDHGLRQFSVYQGQWSAANRDLEREIIPMCREEGMGLAPWGALGGGKFKTEQQREQRKQGAQGRAAEPSEKDLKVSQALEAVAKRKNTIITSVAQAYVMAKTPNVFPIIGGRTIEHLKGNIEALTLALSDEDIEEIESAVPFEHGFPNSFLWSNKTPKNPADVWLLNMGGHFDYVPTQQPITPSARGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAV7</accession>
    <name>A0ABR1WAV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008439</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668096.1">
        <property type="nucleotide sequence ID" value="XM_066812754.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045814"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF60">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="537"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="571"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="157"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="99"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="609" mass="65432" checksum="71A6771260062232" modified="2025-10-08" version="1">MAQPRPTEPEPGQGDNSEVTDFANSDANTKTRSSGSVEKKRPDKDDVDDGDGSTTYASVSSSSLSVNPIPPSASRVPTRGSEPPLSRVVSEVYDGIESRHDVEISGDGGGGGGAPLEEEKTRASTALNPNDPHLVTWTGRDDPANPKNWAYPKKWRAVFIVSCFTLMSPLSSSLVAPSLGVIGKELDVPPGTQQALILSIFILAYAIGPLVWGPLSELFGRIVVLQITNLLYLCFNLGCGLARTKAQLIIFRLLAGLGGSAPLAIGGGVLADLFTAEQRGKAMSIYSLMPLLGPAIGPIAGAFITENTTWRWSFWATTIADAVIQLLGLVFLRETYAPVLLKRKRQRLVKETGNTELHTPYDDPDRTVARTLRTAVARPFRLLATQVIIQVLALYMMYLYGLMYIVLVSFPSLFSGPVSEGGYGESLGIGGLNYISLGLGFFLGAQVCAPLQDRIYAALKRRSARNGGSGVGRPEYRVPMMVPGAILIPVGLFIYGWTAEYKTHWIGPNIGACLFCIGTIIGFQCVQGFLVDTYTRYAASAVGAATVMRSLAGFGFPLFASDLYDRLGLGWGNSLLAFLGIVIGWPSPVLLWYYGETLRKQSPFAAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBY8</accession>
    <name>A0ABR1WBY8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668503.1">
        <property type="nucleotide sequence ID" value="XM_066813161.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046221"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8081028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="97" mass="10931" checksum="0C02E7C2A2993EB6" modified="2025-10-08" version="1">MASVNEEVHYTVGEFKDGAELIPDGIVVYRPEFASWRCPEAEQMKILFCFAPEQVIKLFLGRHWKGLLVGAGRPFFGIVTGIQLREYGSQARMLLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC16</accession>
    <name>A0ABR1WC16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668453.1">
        <property type="nucleotide sequence ID" value="XM_066813111.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046171"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045515766" evidence="2">
        <location>
            <begin position="21"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="265" mass="26647" checksum="B4AD719805724E63" modified="2025-10-08" version="1">MKNIKMLVATLAMGFVGVNAAAQGIPTPPGFIGYANDGNAQDNLDTVARPPQPSPGTILSEPPSGLHIGLKQQQGGSTWMTTVTTTGTLTLTLASGSVTTISGPYAVETQVIESDTTIPITVTETASSQISSMTDADYGASSSSSSGTTATSTSAASTATVTASTSTAQSSDASSSATTPALLSSETTAASSSVDSSASESTATGTDDSATSTSDATSSESASPSSSDDPNSAASHCTAMAMLQKFAVVYIVFQFWDTTFFDRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC94</accession>
    <name>A0ABR1WC94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668626.1">
        <property type="nucleotide sequence ID" value="XM_066813284.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046344"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="441" mass="50539" checksum="150A9F8C0C2DB10E" modified="2025-10-08" version="1">MASGFFKVLPPELLVEIGGFLPLEDQQRVSAVDARLRRVLAPLLFSTIRITNNSSDQDAIDQIVTKYGHHVRGLALTMDLGRFWEDDKKEEGGEDDDEGGDDDGDNDGNADSEAFHAMPSNLNPFPGTPVVVPYLFEDDEYSSWLQNRRKKEWERPADWILPGLPVLTRDLLTVQKLPGVSSVSIRFACDFHNRSYEDWHDWRAALADDNYSMSYDPEQVEHRLSTLDNMWQALTLNVQIRQLAAKELLPVARTPFWSQPAWSAFLGRLETLELGFWEGRPDDWPEKHAFQSDLNLHFYRHLSGKASPLRRLVLVAAPDSPIGPDAYTLGAPYRLSSPKGYMPHIRELRLENCILHPDLATFIAERGRSSLRAVELINCASIVHPGTRRTQRSPMTWMEFFNTIIRSGDRRDIVLEQFRLVRTRDIKLVEGEEMWMWGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCZ5</accession>
    <name>A0ABR1WCZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667504.1">
        <property type="nucleotide sequence ID" value="XM_066812162.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045222"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="34626" checksum="1FCE4B7A668AAB2B" modified="2025-10-08" version="1">MWITSDILCEVATHNRKLNPDTICDRVKAWKSDMGNTKKLAAIITLSGEIARLKDVIIPDDYWQPDLRETLGAQLCAIQSAIDRLKARSPNDASSFGSVLDEVKAYYLKPAHRPEDLGEDHMQMVLEILKYAIRQCRSGTADDSSDCKPKACYGRVSEALEQAFLFRKRNVPYVSDLTEELLNAFKMVHEAAAAFLFFDMKSERTKKSIRCNSTIGEQPRSPGQSDEDEEDDLAEADGYGGEAEGALQTCACHSVTSKMWQIDQDFAQRKERSLAKLKSRDPDSDRARQGHDSKPLNPLPLGQFVEAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL23</accession>
    <name>A0ABR1WL23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4185 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668706.1">
        <property type="nucleotide sequence ID" value="XM_066809783.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042843"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045083183" description="DUF4185 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39745" checksum="70C2B4A1C0FFF840" modified="2025-10-08" version="1">MRAAATALLVLSQVAATSCIGLRNLTSSPQETIDNTRPVGNNIISHDHTFTTEFLGLQLANNSASHRDLGFTGQLGGQWYAVPGPRPPGFHGMVRDAISLCTDNPLVVHDLHLDSEGRQQQFVPYNEEWGEAADFGFGGTSLVEVDGETNTGALFYLINGNKTGYRGAGIAKVQLVDGAPTVTHRFGDRGYWWDANTTARYGDIAAFRDPRSDYVYAWGGAPMNITDWVQGAYVYQCRVKAADAFDITRYEYWWGRQMGWKSEPPATFTAETAVMWMSGQGQVVWNQHLGCYVFFSYAPHPQPEGPWSDDVKVFNATPIGQDGMTYAGVAHPYLDPSGRSMVISYTNNNNIEVIRVTFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLS2</accession>
    <name>A0ABR1WLS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668998.1">
        <property type="nucleotide sequence ID" value="XM_066810075.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043135"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF6">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046893787" evidence="7">
        <location>
            <begin position="24"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="9"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="412" mass="45749" checksum="83B4F6D06D51E7E2" modified="2025-10-08" version="1">MSPNGSSPHVLILGAGLGGLSLAQALRKRGISFEIFERDNRDLERPQGWTVSVHSMVEDMKESVANDMPPFNTVDHLDSVDIPCEFAYYNPDSTAKMGYRDDGSRTYMWANRSTLRNWLSTHIDIQYDKHAIRIEESDKNVTVHFKDGSSATGDILVGAEGVHSMTRKYILKGNDPVQSEKLFLVSGDVHLTKQEMESQMTLSHSSYLVDFPGAEDGKTYHLFVGLDKLSSPSDPESGADYYFHLTGEDEAADGDGFWTYSATREELCAFALRQARDLPERFRCVIDKATAERMKTPPVRLNTLIMESLPVGRVTLLGDAAHVMTPFRGEGGCHAMKDGLNLARAIDKIDKDNDQSLREALDEYQKEMIKRGCGAAAMSSKEYTTAIDHEKPDSRAVAGMAMVALPQERVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM49</accession>
    <name>A0ABR1WM49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc finger Mcm10/DnaG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MCM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669118.1">
        <property type="nucleotide sequence ID" value="XM_066810195.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043255"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040184">
        <property type="entry name" value="Mcm10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015408">
        <property type="entry name" value="Znf_Mcm10/DnaG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454:SF11">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09329">
        <property type="entry name" value="zf-primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger Mcm10/DnaG-type" evidence="4">
        <location>
            <begin position="474"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="631"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="670"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="583"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="210"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="226"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="405"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="631"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="672"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="684"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="735"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="766"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="791" mass="86098" checksum="B977C41DE36123F7" modified="2025-10-08" version="1">MAQRSGAGPPAQWPPRSPHEALASTPGGRERMRRMAERSSPSPSPLKRARSMSALAARSATPQNNMDDEDLDVDMEDEEDDEETLQLKLQAIQAKLKLKALQRRQKQAGGSVDLNSSTTTKPSPGHDIVAASRAQSRATMLKEAKKVPPQPQTEVQVPVSPVRRTQTAQSQRSPSRVLLGIDKGLKAKDVSLKRASSQRGPRDGDGPSSGYLQRSRTPAANQENLISRDRPKSFSERLAEARNEEAAKKERQDRIKSVRNDTFQVKQEEVEQYKSQAVEIPEAPSEQGSYSRAEILAGGRIKRSNTVPSVRRGDDINGEGGAANSDEAASFEPYSALHLSKRILPHSVLARTLSGKKPYLIKDLLACVKAPNFELPDIEQDIVVLGIIASKSDPKAHKPPPGGSDLKEKKNRFADGDDPRGKYMVLQLVDLTWQLDLFLFDSAFARYWKLSPGTLVAILNPMLNSDGDTVLEIGTARDLGYCKSVKKDGNLCNSWVNKKRTEFCEFHMNAALEKHRFHRQDINSAAGSGMGARPKNHREKWQNDNMKKSTTSNYDRVSGSQYYLSHASAASLIDGEHLAFGGVADRAERKEALRRRLEHQEKEREIMKQLSNLGRGAGREYMKMADRTNQLGSSVSSAGGTAQDSPSMSQTPAYDAKSLGLVAPRGADAKKVHLSPVKRKRNLSSFNSMSSTGSSSSSVKAAKTAPATQAKSEGALGWGTSLKDKLSNMKNGQRFDGATSAAPAASSSFSDGGSFQSSVSLTPAIKGKDSREKAELPARKKDAVCNGKGDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM50</accession>
    <name>A0ABR1WM50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4 15">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 15">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_005871</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="15">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15 16">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4 15"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669109.1">
        <property type="nucleotide sequence ID" value="XM_066810186.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043246"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016271">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF61">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000852">
        <property type="entry name" value="Phosphatidylserine_synth_fun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 15" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11 15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 15" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="13 15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8084600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="244" mass="26545" checksum="94D958A4C598222E" modified="2025-10-08" version="1">MSKRTSAASSNGAALAKQSSDITEPAYNKQKDLLSSSTGHFSLLRAMHMADYITEMNGFCGIMSIFSSLRYCLGDPTEKSNLYLALAFLPFGLFFDFLDGRVARWRKKSSMMGQELDSLADLISFGLAPACVAFSLGIRTTLDHVFLAVFVLCGLTRLARFNVTAANIPHDASGKASYFEGTPIPTTLGIDALMAYWVSQGWVLDQVPGGLWLAGSSLEFHPIVLMFLVHGCLMTSKSLHVPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WML5</accession>
    <name>A0ABR1WML5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-hydroxyacyl-CoA dehydrogenase- NAD binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006046</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669284.1">
        <property type="nucleotide sequence ID" value="XM_066810361.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043421"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075:SF3">
        <property type="entry name" value="3-HYDROXYACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075">
        <property type="entry name" value="3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="4">
        <location>
            <begin position="13"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="3">
        <location>
            <begin position="189"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="311" mass="35144" checksum="8A5CB8B7AA41B370" modified="2025-10-08" version="1">MSWTNPPTENRSIAILGAGVLGRRIGAAWAAGGYTVHLRDPDAKQLAAAHEYIQEHARDYKEDVKSSDLRVELFEELEPAVKNAFIVAECVPEQLPIKQETFSELERLAPQDAVLTTNSSSYKSREMSRHLRPETRARVLNMHYMIPPRNRVVELMTCGDTHEAIFPWLLDILKTLTMVPVQARKESTGFVINRIWAAVKRESLMVLSEGVATPEDLDAVWHEMFVKSEIPPAGGMDLVGLDTVSYIEQHYIKERGLQDPGVIDYLQKYIDGGSSATRPRIRAVCTHRRHSKLNGFSKQDRTSLFTRGQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNA2</accession>
    <name>A0ABR1WNA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Intermediate filament protein MDM1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006262</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669500.1">
        <property type="nucleotide sequence ID" value="XM_066810577.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043637"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06876">
        <property type="entry name" value="PX_MDM1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08729">
        <property type="entry name" value="RGS_PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="PXA" evidence="7">
        <location>
            <begin position="102"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="5">
        <location>
            <begin position="418"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="6">
        <location>
            <begin position="879"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="574"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="709"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="843"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="574"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1187" mass="133138" checksum="5CBD5747E7A20DE3" modified="2025-10-08" version="1">MALSGRDAALAGTVCFFAWGYVTNWFPMLRWAGYAFVAGCVTTFLSSLLLILLTSKGSVYSLRHHSSRPNSVNFAGPVSWRRETSSLRVRQIYTPVPLYPDSRKISHALDDLLSLIIRDFVQSWYSHISKNPVFANEVDKTARLAIVDLRDRLSDTDLVEVVISRIVPILTAHFRDFNNAERAVRGRKLNRDVTESEELDLAIAAKYNEGRLHPAASMAYSDTKMIQQEHLRKTIARVLPKILPSNILNSRAVSSIIREIVACAVLSPVITMLSEPDTWNQIMESYGRSMLQDRSTVRKLRAALDTHASPAPKASKSTQFPRLLPGDAERKFEKFIRAIRKINNLSDARRFRSEVTSQLKRDSQQDDQDQVYIRRLEMGKRLLDQRVQHLAAGGDRKDVPMFTNPTPAPGASRLENASLADLLRDPSGLSYFMEYMDRQRMMPLVQFWLVVDGFRNPLEDDGPEDEQLPSQLSPWTDSDRTDLAQIDQAYLSKPELRVPDSSRKDIRAFLQAGKKATPAQYHQARRAVLRAQSVVLEEMRSKYFQGFKKSDLWYKCLASEEAATRAQSIPYVPASASAGPSHPPLSRASQSFGLKPAPVSKLNPKLNATSAQVKRGLSATDLRSSAANGSHSPDPLNGQRRSLDENANSPLFDDDDYEHDPMADSVQSLDRDQANTPPDNQVVQAMEEVLNTIMEDGNRPKTAEDLRQSLFGNDDGTLSVFSNNDNDSVRGSVELPRQSSGKEAEKPSLSSLGLVSPASRIGVFVDNDLFADEDKFLSDDQADTDDGNLANVEDEVHEAAPGDLGLAEAITVLTNDIDRLVAQEAVIDSLTKKAELTNNTPELRILRKSKASLQRELKRKELQRQQYVIQESDNSLYGRSSIRIKAIQVGREPDGKEFAMYVVEVQRVAGEKMPAATWVVTRRYSEFHDLHQRLRHRYPSVRNLDFPHRRVIMKLQSEFLRKRQQALEHYMQELLRLPRSLPQQGSPCLSFPKHGMEDILGNIPVLDQLSVAGQNLIAAATSQLNTVQLPANIQEDALTAAEAEAELNAFENKELEPFIKPICDIFLEVFELNRGNNWLRGRAVVVVLHQLLGGTIERKVRDNVKFLVQEDAILKYIGLVRDSMWPGGQMNRNKQARTSSEKSKTRREAGLMLATLVPDLAGSVVGRINAQAASRRIFATLNNPRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNI8</accession>
    <name>A0ABR1WNI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669600.1">
        <property type="nucleotide sequence ID" value="XM_066810677.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043737"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="77"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="701" mass="79075" checksum="4347DD7B898297DB" modified="2025-10-08" version="1">MPSGSESESGSDRSGSVAPDHDDIDHNVDKSNSDGSDESDDDENHGFLDVEAVESGDESHEGDTDDESEDGFEFESFPQFTRLPIELRQRIWEIFDPDMRAPARIFGFRMPFSGANELHEGPLLERQTAPARAVLATHHESREYALKYYPDAIEKGGEPGIIRYRKESDIIMVSGYFRDFASISSWQESDVFTGIRNIALDLEGTAEHQYEDLLSTERPQWPNLQSTYFVTQAITHRTRNLRWCGSDAVQTYHLQVEELDTGLGEDYEAFYCWPQGREREHTNLPIFGHEEEEDGEEEGEGINKSSLGQKCSVIKIGEETIWPIVVFDFEGSGVHRHDKLREIYPVGGNWEEADDWHSDEFSGDEEDELSPDEYESEGIDDGSIDEDEASGDEDDLQVLDDDSEQEFDTSVFNGFSPPPDDSAAAVEPANFSSVEPESAHFSSIEPESPDHSDAEASDTADESVRNVQRPGRRVLADSEDESGDESEDEEQNDAQPTTRRKRAIMSDSEEEEGEDMGVEDEQARLSNRRKRVVMSDSEEEEEETEEEEQTEPNKRRKRVATSDSEDEEEPTRATKRRRRAAMPESDDDDDSATEQGEAESVSDDDSEDDEDESEDEKPQKKPSLAERLQLFRSEVPVAPSPEAGSEPDSDMEQLRNGDYDDPFADTYDRDDDGDLDALSENDQLLDMDEDEEDPYGDDGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNY5</accession>
    <name>A0ABR1WNY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aspartic peptidase A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_006518</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669756.1">
        <property type="nucleotide sequence ID" value="XM_066810833.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043893"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06097">
        <property type="entry name" value="Aspergillopepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034163">
        <property type="entry name" value="Aspergillopepsin-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF1">
        <property type="entry name" value="ASPARTYL PROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="106"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8085247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="459" mass="49920" checksum="D215B8685677F539" modified="2025-10-08" version="1">MDAILSSQKNLIQSMGLSKVRVVRNPNYQSHGTKSYVYLLNRFGFQPTKPGPYRHVMRTDQHGLAAVKQALVGGRARQNRVLVKQSSGDANHGEVTAEDQQNDSMYLCPVEIGTPAQKFMLDFDTGSADLWIFSTEQGSTKGHNAFDPKKSQTFKKLPDRSWKISYGDGSSASGDCGTDNVIIGGLKIQNQVIELAKKMSAQFAQGTGDGLLGLAFDKINTVTDNNGTHEPAATPVENMIAQDDIPKSSELFTSAFYSDRDQKESFYTFGFIDQDLVQGQDIYWTPIDNSQGFWQFPSESFSVNGQSTEQSGNQAIADTGTTLALMSDAACKALYDQIPGATYDEQNQGYVFPLSTSADDLPDFSVDIGGKSFVIQKEDLAFAPADDKNWYGGVQSRGDMPFDILGDVFLKSVYAIWDQGNTRFGVVPKIEKVQNLTPPITGSGAGGGEKVTSVDMVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP21</accession>
    <name>A0ABR1WP21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668739.1">
        <property type="nucleotide sequence ID" value="XM_066809816.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042876"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364312" evidence="1">
        <location>
            <begin position="25"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="243" mass="28169" checksum="7E0C18E0324535D1" modified="2025-10-08" version="1">MGNIYVRNTWTFCLILFLVPLCLGHDQTDTSACNFTIDWVDWIFQGNFEATQDCGDFNLILQEFVNDFKHDYCLVTRQYVLGYIREGLRFNLEAKKDAKMPEDCEIERWWYEGYYDYERSRVAFCKNATATHTTALSYTQPFFNLIHGPRTFCHNKLKEELATIGNPDIAGWGVMTSFPEVYEYRLLTMAPAFTVLPVLVAHTLYEGVGGAGLSPLYNGNMGNLVRWRSRPTVPCYRRLWKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP48</accession>
    <name>A0ABR1WP48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668769.1">
        <property type="nucleotide sequence ID" value="XM_066809846.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042906"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539447" description="F-box domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="53915" checksum="F89E566E36787DE6" modified="2025-10-08" version="1">MVHQLATLPLELLHAVASLLLRPDQAALARTCKSLNVLLTPSYGGDIELHFRGTHEGVNLDAKLGNEDDNDDEEPSPEERAEYPFWDIVKEPPLRKYSQIEFDGTNQAGVDLDHHAHIDGDELGTVGRASDMGNRRNLQFAKEEKSARVCFITPAPRWTELAQHVRSLCMSIGMDDGVIKVLSDLRNLRSLELVGLPIPEAKPWPSTAPEMRMPGLKNLKLRGFFPVAFLKAIFTNAETITHLNLGLLATKFDDEKNSCGILAGRFGGAQHDGDDDKDREEKDDDEDDDPQPWAFHNPIWLSDDLARGFNSLTHLHLVKPYSGYSSLDYGSLDEPPCATKSASMAKRGGGLGRHPVLPIGAAAPSPAGGGKGYGALRRLALRGIRIDGISTTSGGSGDGDEEVEAAVLPGIGGRALDNGALLRRSYPDCDVELVQNDVYGIYPYDGETYDCWDERRKEPRQDEGDGLLEDADYYRDYIRRYGPQWRIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQH1</accession>
    <name>A0ABR1WQH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrodipicolinate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670293.1">
        <property type="nucleotide sequence ID" value="XM_066811370.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044430"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF38">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHETASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G00110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="33644" checksum="9AEB685561B1C360" modified="2025-10-08" version="1">MAIQPLDLAGLVPAPVTPFTKEGKVDYPAIQRLGSWLGSIPGVKGLVVLGHAGEGTFLTQDEQLGVIRAFVQSVDDKIPIIAGVTGEGTEVAALEAKRAREAGARAGLLYPSHGWLRFGYQVGAPQDRYKVVYEVSQLPLILFQYPDVTKATYSLQTMLEISAQPGVIAMKNGVRNMRRWDTEIPVIRRERPDLTLLTCHDEYLLHTCFDVDGMLVGYGDIAPEPLLCMIEAGKQRDYAKAHAVHDELLPLAKSVPPGSHMEGTVALKHALVARGILEHATVRSPLLPLPDGAEQEIHAAIQSAKLSRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRU6</accession>
    <name>A0ABR1WRU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669592.1">
        <property type="nucleotide sequence ID" value="XM_066810669.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043729"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="121"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="293" mass="32644" checksum="FC0484C51E908939" modified="2025-10-08" version="1">MKNHNIAFIANSQDKRQILRRLTRRINVKPARIFVPQHPGETPEHHFPQQAVYRIQNPGPRFVNRYDSKEILMVVGDSALKSGREDASAGCSFIYKGGAAATAAFAGLSVLGQANVPVAFATTTFPYMNDGSCRDVGGIIAFRLEDKGPGGAAMDPTSNRAKMRAVIAALEFRAWADEGWRSIVIATDLEYVVRGATEWLPRWVQNRWKKRPGGGGGRVANRDLWEELQGIIDRLRESGTDVAFWYIRPRILSLQGSALAHDAQEAARKAAYREPDICAEEFTRFCEIDLGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXK8</accession>
    <name>A0ABR1WXK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Geranylgeranyl pyrophosphate synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670789.1">
        <property type="nucleotide sequence ID" value="XM_066807171.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040231"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF2">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="41140" checksum="3404002289B19472" modified="2025-10-08" version="1">MRATITRKDLEGHASQASISDVQHLSSYSWIDLPEPTIAVPGMPPKWQPPKKKRRGPLPKDSGLQYLAENEARHPDSPMEPLFRAVYSADPSFDVRNIDVVTDAKNIRKLLSFVDPASARLGLQPFTIHAELEGESTVTLSSVEARTSTFIMPTQFEGYGLEYKKAYTAREIANSTGHYRVIKYSFGGLNYVVRFEADAYVDPPGSEPQADSKSEDPIADIINNVDHQSLGSGSKLSVRKQGRIIPLDSILKIKPRVGHSPLKLFDLAPPLWISQTRKLVCAYHYQGEFEETYVEDVVKKITTYERMQQPSFERLAALMTKLTEQVKSFGGSCAIKCYSRDADELVVQRIDGKPMLPLDLYSKWDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYB0</accession>
    <name>A0ABR1WYB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitin deacetylase</fullName>
            <ecNumber evidence="4">3.5.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003075</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate</text>
            <dbReference type="Rhea" id="RHEA:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9597"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57704"/>
            <dbReference type="EC" id="3.5.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:10465"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.41" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671008.1">
        <property type="nucleotide sequence ID" value="XM_066807390.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040450"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10958">
        <property type="entry name" value="CE4_NodB_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF137">
        <property type="entry name" value="4-DEOXY-4-FORMAMIDO-L-ARABINOSE-PHOSPHOUNDECAPRENOL DEFORMYLASE ARND-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="3" id="KW-0170">Cobalt</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="74"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="268" mass="30760" checksum="EAECE0607A3F5674" modified="2025-10-08" version="1">MVRLPAVFRLPPKLRRRARRRRMTTLVALVVLLLVLVVPFYVIYKPPRLLIRYFSRRWPDVLWEVDVADPKHDKFVALTIDDAPSEHTEEILAVLKTYEAHATFFTIGGQVSGREEILADVVRGGHELGNHAMHDEPSRALSDAELTAQIETVRDKIRAAYREAGSEDVPPQYFRPGSGFFSDRMRRLVDKLGYRLVLGSIYPHDPQIQYPAINARHILSMLRPGAIIICHDRRPWTPPMLRTVLKEMKARGYQAVTVSELLRRTGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYI1</accession>
    <name>A0ABR1WYI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671094.1">
        <property type="nucleotide sequence ID" value="XM_066807476.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040536"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="655" mass="73185" checksum="A2778183CF681E20" modified="2025-10-08" version="1">MASRDRRAVWVDHWTVHQDGDELLEDSTHANPEQDMENSSVPRYRGFTPAPGDLCAMKETALSLAGGEGSNNAQAGQDQYFTTAARGNETRGPGYTDTSGNGQHAKETPVARRAIGGQLAKSRWAPATMVKGSGIWRGPVKEFVKANDQSLTNEAPTTIPENPKGDVYVPPHLRPKPAQGKQKAPEPQQQLHVAPARSTQHVVKNEPRNELPMTSALVHVSGRTDQDAAGTLAVLKSPESTEQKDEVSTLNSRLEASLAIFGTDPPEADPDRDPRGVTPIQTWTEQDWGMTRRPKKKKSFDSESIARDSETPDAAEAAVFQNRPKVYEECDVDCETGGLLAPVEYPRTMINHNETVMLKKRLHSTSETLIVQERKKKEQAEFMRVQRERIEKARLAPAEITEETEPAMTRANPFECRAQCHIRPAELGDMAAVAGLYKQEVETGWRALDQDVVQPPSWERILGNCQEQNLPFVVALSGYRDPRMPIGKAGHRVIGFAFLEVASRGIMGSVTTNAKCSGRVYVMVDPQHRRARIGTALLDAVLRAVSPQYGPKENSYQWENPQDNSTYHECRYNSHSEQRQWRSILMEVYVQNHGTKEKTTMGEEYQAIWNWLEMDLGMNLISHSPMFGRADRLPTSPLLDRLVFEHRCCPAEILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYK5</accession>
    <name>A0ABR1WYK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003199</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671132.1">
        <property type="nucleotide sequence ID" value="XM_066807514.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040574"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF74">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="49"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="492" mass="55196" checksum="6C7D64E8A0A13A18" modified="2025-10-08" version="1">MADALDTKVAETEVEKQEYAENASVRRAAPPAIDPEVNRRLLRKIDWRLMPVLCVTYALQFWDKAMLGQAAVFGLREDLKLTHGSSFSWVSLILYFGHIAGMYPFSWLAQRYHPKRVCSTMTIVWAVIVLTTPACTTYSGILANRFFLGFVEAGISPVFMLVIALWYTHPEQVLRSSIWYSFSGGSNIISPLVNFGLAHIIGGGRAPWQYMYFFAGGITLLWGIALIWIFPDVPQEARGFSAEEKRLLLERVRVNNAGSENTHVKFYQITEALMEYQFWGIFVLAMLSCTGSAVVVQFASIVFNGMGFDKYTSLLLNLPTGGMAFLCVIGSGYCGRNFKNARFHLITIGCLPVILGTSLVWQLTNEQRAGRVVGFYLINFFSFVWVQCIGLGTSNIAGHTKRTIYASGTFIGYSLGNVIGSLLFDAKFGPRYDESFTGITVCFAVCCVLGEVIRFLLARENKRRDTKYGPPEWSHGLEDLTDRENKSFRYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYK6</accession>
    <name>A0ABR1WYK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pre-mRNA splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003164</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671097.1">
        <property type="nucleotide sequence ID" value="XM_066807479.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040539"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027105">
        <property type="entry name" value="Prp31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019175">
        <property type="entry name" value="Prp31_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13904">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13904:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09785">
        <property type="entry name" value="Prp31_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Nop" evidence="10">
        <location>
            <begin position="273"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="389"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="482"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="574"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="40"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="579"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="673" mass="72752" checksum="CA0F65CD1B2AE2B7" modified="2025-10-08" version="1">MSTLADELLQDFEESGSENGDEQNDLGLEGDAPTVKGGDDDNNQDDADDGDMVLDGDEEAPDDQDEEMGGIDPLEDEDEAKAKVEKMQLGNVKDVRKVSTVMDRLEPLLRDIARFQSQPLESHAINIGNIEDNPEYKVLTESNTLSTQLDGEIMKVHKFIRDHYSARFQELETLVQNPVDYAKAVAILGNGPMDSDSIKRLQESTNNVLGESLKSVLDGPTLMIVTVEATTTKGQEVSQEELDRISRACLMVVSMDKAKKTLTEYVQSRMNVFAPNLTRLLGSSLTAAQLINTAGGLTNLARTPACNIAAWGSKKQSNSAFATNIGVRQQGFVYQSPIIRGVPNDLKTKAMKAVTAKLVLAARADTGHTYPHGDYGDELHNQVLSRLDKLTAPPPNKGQRALPAPDDKPSRKRGGRRARKAKEATAMTDLRKAQNRMVFGKEEKEVGYGTGESTAGMGMIGASNDGRIRGIQIDNRTRAKLTQKHKGWGEATPVGGAASSLRGFGQGGSTIDLRGKGIRTSGVGSTIGGGGSAGTASSLAFTPVQGLELVDPKVQAELKRKRQADEDRYFKGGTFTQVSGSGNNNNNGSGTFKVPGQPPSKRLTRGLRNLWRPRRYLQSKVAFSGFLVCATWVAPAWPDRTTLQVEVGASKLPAYIRSKHAIGLMLRVGEKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYL4</accession>
    <name>A0ABR1WYL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger protein RME1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671146.1">
        <property type="nucleotide sequence ID" value="XM_066807528.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040588"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057218">
        <property type="entry name" value="DUF7896"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42031">
        <property type="entry name" value="KEY LIME PATHOGENICITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42031:SF1">
        <property type="entry name" value="KEY LIME PATHOGENICITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25438">
        <property type="entry name" value="DUF7896"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="694"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="747"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="878"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="905"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="937"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="992"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="835"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1076"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1076" mass="120853" checksum="85AE5FE734D25582" modified="2025-10-08" version="1">MAADTYPAEPRHDGRGSQSLDTPGASAFDQSLDPTIRSLFEQQAAIQAKLAALLPAKHDPNSRLELDMLRHKLRALEAYAENQNLATAIRPLSDAEEARALQYKCECIESSLIDQGLDLLDPNFLEALRHPAQSDAPPEYSTWLEKNVSFYDPIFRSLRMRETLPVIPRNQAPFKCWDERCLYYIYGFANFEDRDQHMRDHATPSKRDSGLSVNSVPHVVFPEHTTARLFSADRLKTNSMVPLPRLSVPSNLAPWPLSLRSEIDEKPQLHTLLCDSQDDCAFCAEPPASAGDEFWSVLGCQRGPLLVLADYMLPEILSPRQVQTPVTSPMARRRNMNEYLERTYIVSPAMSDLPTRRTPSIELPPVLKVLAASWNAEGIPFRFWELFKLSGYLSPNRELEKQTYPVLYRAKLLLREILFYDLQQTEPSIRTDVNMANAQLLPEDIDYDGRNRLIYNCMTQFLQSFESSTIRRVLTEPKSWLAVFLSLCIFSIVRTILADLISTPSRGGSAHAQSAMPMPTGATAMHSVYKLLVSVFAWSTPMVLDDPGVDMDDSDKFLFAATSGAIRKDEWPQWGIRSSKDFLLGLGSGYLADNIGFNGFFRQRTPIYRTVSYQTPSVATQLGEPRKPVPEWRPIEAWGQRAETAEVGGPAFGLEPARRHTVGESPAFSRAIARGLVSPSKLRTSYHRPPLRRVYCSKCNEYPEGFRGEHELRRHTDAKHAALVKRWVCTEPQSHSPSSPQPVIPLAKCKACVTQKRYGAYYNAAAHLRRAHFNPHRGGKASGDWPPMTILKDWMREVRQSIDVSNENDSDSGDEESDARMVEEFAMPRQPSYLEAPRLAPAPPPPQGPLLAPSIAPSLDSAMHSSSPIAPKIEDNRNKCPHPDCGRVFKDLAAHMLTHQEERPEKCPIETCEYHIKGFARKYDKNRHALTHYKGTMVCPFCPGPGTAYEKAFNRADVFKRHLTAVHNVEQTPPNSRKMIITGNSSRGGGDAKCSICQTRFASAQEFYEHLDDCVLNEGGGGASTPSKTEEKTIRVATEDSDDRSRHEDDDKAKGANRDSQQRWGDKMDVDSDGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZV4</accession>
    <name>A0ABR1WZV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ras modification protein ERF4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003638</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Interacts with ERF2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671571.1">
        <property type="nucleotide sequence ID" value="XM_066807953.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041013"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019383">
        <property type="entry name" value="Golgin_A_7/ERF4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051371">
        <property type="entry name" value="Ras_palmitoyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13254">
        <property type="entry name" value="GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13254:SF0">
        <property type="entry name" value="GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10256">
        <property type="entry name" value="Erf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Golgin subfamily A member 7/ERF4" evidence="8">
        <location>
            <begin position="39"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="171"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="204" mass="23031" checksum="019D4401F2C4BAC4" modified="2025-10-08" version="1">MGDPDQPDMGEEWGPQHPCFPHLNPHVPIDSPEYAATRVIRIRRDWLLEGDLAPTFSNLYPEILDPAGITEQEFRRVIEKLNNELVPIFNPYYWRNIVDGVMGLVTGWIWDDLGLTYTKSRLKTLELWIEKWNTEMEKAIGIEDPAMAPKIVPLRRTGYMNLDIQIPDPEIAPAVTASQPNSRSGLPAEPEPAVTADHAGDAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X022</accession>
    <name>A0ABR1X022_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003698</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671631.1">
        <property type="nucleotide sequence ID" value="XM_066808013.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041073"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF28">
        <property type="entry name" value="ISO-OROTATE DECARBOXYLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="112"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="377" mass="41191" checksum="553C80B109FA49CA" modified="2025-10-08" version="1">MASSGSRVVDIHTHMYPPAYVQLLESRQTIPLIRRFAGAKDPRYIILPAEAESLEKISQAGEAATATTQLPGRPVTSHYSSLQQKIHFMDTHKIDISVISLANPWLDFVAEAEAAETARSVNREFESMCLEHPGRLFFATLPLSAPAEELLAAIEFHCRGVILGTSGLGKGLDDKRLIPVFKALAKNGLMIFLHPHYGLPSEVWGPRATEEYGHVLSLALGFPLETTIAVARMYLAGVFDEVPDLKMLLAHSGGTLPFLAGRIESCIVHDGHLVREGKVGANRRTVWQVLKEQIYLDAVIYSEVGLKAAIDASGVDRLMFGTDHPFFPPLTSDEQGEWESMTWNKAAVEKALGEGSQGTLAVMGGNAIEVLRLKEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X023</accession>
    <name>A0ABR1X023_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671630.1">
        <property type="nucleotide sequence ID" value="XM_066808012.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041072"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047521920" description="Extracellular serine-rich protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="23907" checksum="0D4BA69370FADD6C" modified="2025-10-08" version="1">MFTIVPFTAALALLASGAYSMPTGTTCDKPSQVAAPPTGVTHKVIAGANGQLRFEPESVVAAVGDIVEFQFHPKNHSVAQSSFAEPCAPLAVPAALPPPANATGYSSYSPYPRRSNVGRGRAAADAYPFFAGFDFAIVEGPANHAFQVLVEDTKPIWFYCPQPMGAHCTNGMSGVINEPRDGPNTLAAYKKAAKAMMTVVPPKVHGGIKSLWWRRSRLLEFDVAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0R1</accession>
    <name>A0ABR1X0R1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671911.1">
        <property type="nucleotide sequence ID" value="XM_066808293.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041353"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="255" mass="27810" checksum="81D71D1F49303D0E" modified="2025-10-08" version="1">MGISLSAARYLAPAAFLVDFAAQLYGLLSSPNMKDVHDANISFFSPLPLFIACFFFPQQIFQAVWLWMLWKAKPENVEEDRALRQMIDYVPYYAVGNLCIAAIDAGVGAGTTAWMVVWNHSDLKTANDFVIVNSCLQLYYVFTRLGPMDLASWTSVLTHVVSKMFAGNGLLDILHNSSAAYAVGQAPNTAVKVLTGLGFAALASCSDWIFGGCLAYDLIALWVGQRVYGNVAWSNLLGGYVSIVAGLVVVRNCLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X101</accession>
    <name>A0ABR1X101_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleolar protein 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004003</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-25S rRNA processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRM RBM34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671936.1">
        <property type="nucleotide sequence ID" value="XM_066808318.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041378"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF25">
        <property type="entry name" value="RNA-BINDING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="318"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="24"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="428"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="454"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="470"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="507"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="561" mass="60182" checksum="30BF662FA316DB29" modified="2025-10-08" version="1">MGSSKRATLAASKDRVDPTLDALFASSSGPVKAPPPSRYKSLVPAKVDKAERQGGADNSPSGDDESLSELDSEEGSLTTDVGIDDGSEDENVSGTEPEDVTVSASDAATSDIGKKDRKRKRKDLHDDLESKYMSKLVSEEGDKSHGDKRRKGESGQAVTDQAPETVLDEEEVDDGIPIVHESLRNADDGDASEIDKANRTLFFGNVSAEAINSTKAKKQLLAHLGSSLSTLDQSTGPHKIESLRFRSTAFGAGSIPKRAAFITKSLMSSTTKSTNAYVVYSTLLAARTALKALNGSVILDRHLRVDSVAHPTPVDHRRCVFVGNLGFVDDETIVETNAEGETVTKKRSKVPADIEEGLWRVFEKAAGKVESVRVPRDPKTRVGKGFAYVQFYDGNHVEAALLLEGKKFPPCYHASCVSTKFKAGAMPAEASKGSSEGPKSTKYKFKATPEQQSLAGRAGRLLGRAGAARHQREIRGDKRNSRDDGPATGSNADTLNIIKTPEQIVFEGRRASAKDGKPRDLKLGKGKGNKNKKSVTSAKPGRGAKRAAEWRKKSSGKPSVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X161</accession>
    <name>A0ABR1X161_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004076</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672009.1">
        <property type="nucleotide sequence ID" value="XM_066808391.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041451"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019716">
        <property type="entry name" value="Ribosomal_mL53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042776">
        <property type="entry name" value="Ribosomal_mL53_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28236">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L44, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28236:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10780">
        <property type="entry name" value="MRP_L53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="98" mass="10967" checksum="A02F5A84B2C14AD5" modified="2025-10-08" version="1">MITRFITEVNTKFNPFSTAARSTRLFLSSLPANARNQGMKIDTKLLPRTSADPAMLQVKFKDGKEMNLDGAKLGIKGIIEEVDRHSRFLQKQADLNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1I2</accession>
    <name>A0ABR1X1I2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672187.1">
        <property type="nucleotide sequence ID" value="XM_066808569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041629"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="148" mass="16298" checksum="74C03504FCE69FB3" modified="2025-10-08" version="1">MHKRQTGICSNATKNAHRRNGRLPSPSLLQSVPPSPTLAMATELSETIVVPCSPRPRAGLGSLYDPPSDEAGRQERQPELLTSVRRSRQLKVAATPWNKYIASPTPTPLSSTTAEAWRTDSIPCPVPDWLRHIMASKMVRGNVLFFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1L4</accession>
    <name>A0ABR1X1L4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="12">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_004185</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>S-(hydroxymethyl)glutathione + NAD(+) = S-formylglutathione + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>S-(hydroxymethyl)glutathione + NADP(+) = S-formylglutathione + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>S-nitrosoglutathione + NADH + H(+) = S-(hydroxysulfenamide)glutathione + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:78371"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:145544"/>
            <dbReference type="ChEBI" id="CHEBI:229723"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a primary alcohol + NAD(+) = an aldehyde + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10736"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a secondary alcohol + NAD(+) = a ketone + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17087"/>
            <dbReference type="ChEBI" id="CHEBI:35681"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="12"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672118.1">
        <property type="nucleotide sequence ID" value="XM_066808500.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041560"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF12">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE CLASS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="13">
        <location>
            <begin position="20"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8089224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="380" mass="40378" checksum="79809AD6611B03C4" modified="2025-10-08" version="1">MADTVGKPIKCQAAVAWEAGKDLSIEEIEVAPPQAHEVRIQIYYTGVCHTDAYTLSGKDPEGAFPIVLGHEGAGIVESVGEGVTNVKPGDHVVALYTPECKECKFCKSGKTNLCGKIRATQGKGVMPDGTSRFTCKGKKLLHFMGTSTFSQYTVVADISVVAVQQDAPMDRTCLLGCGITTGYGAARITANVEEGSNVAVFGAGCVGLSVVQGAVAQKAGKIIVVDVNPSKEEWSRKFGATDFVNPSKLEGQTIVEKLIDMTDGGCDYTFDCTGNVGVMRAALEASHKGWGQSIIIGVAAAGQEIATRPFQLVTGRVWKGCAFGGVKGRSQLPELVQDYLGGKLKVDEFITHREPLKDINTAFEQMKAGDCIRCVVTMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X223</accession>
    <name>A0ABR1X223_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mitochondrial phosphate carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672359.1">
        <property type="nucleotide sequence ID" value="XM_066808741.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041801"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40135">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40135:SF1">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="88" mass="9814" checksum="25D98FC61028BC31" modified="2025-10-08" version="1">MVFLTRLVSMTNFAVASSALGFQVFVLYPWHITLDESFEELKKEHIKVLGAVSDIAKAVDPDERKGLQKSILSRMSTMPFAAAKQTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X293</accession>
    <name>A0ABR1X293_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arp2/3 complex 41 kDa subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">p41-ARC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004465</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat ARPC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672398.1">
        <property type="nucleotide sequence ID" value="XM_066808780.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041840"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017383">
        <property type="entry name" value="ARPC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709:SF2">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="353"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="494" mass="54020" checksum="80B6ECE17719FC36" modified="2025-10-08" version="1">MPGPEVHHLFHRPIADHSFSADRKILAVAKDSAVELYGKVAGAFKLKDELKGHDKTITGVDIAPNSGRIVTCSQGYKPTLVLLRIARAATFVRWSPSETKFAVGSGDRVIAVCYFEEENDWWVSKHLKKPIRSTITTVSWHPNGVLLAAGSTDAHARVFSSFIKGVDARPDPSVWGERLPFNTVCGEFMNNSAGWVHSVAFSPSGDALAFAAHDSSITVVYPTAPEQPPRAVISINTQLLPFMSLIWSSESEIVAAGYDCEAFRFQGDASGWQLSGTLESKGRPGLGDEREESALNMFKQMDLKGKAKDDTQLKTVHQNTISTVRAYESNDGNVTQFSTTSTYLGALDANRRARESCSPIPQTPNHTDPLGHPDDGDSNRRVPQPSSSLLKNVSTICNQLWMGSQRDRLDVLNVEREAAKTMALLLEWAETVVLGDYDEWALAGEDAFWRVVRAGRHLCDWLGVQESIDAMDKLETQLADEGGGGTWSGVSVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2Q7</accession>
    <name>A0ABR1X2Q7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">DNA replication complex GINS protein PSF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004666</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.</text>
    </comment>
    <comment type="function">
        <text evidence="1">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the GINS1/PSF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672599.1">
        <property type="nucleotide sequence ID" value="XM_066808981.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042041"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11710">
        <property type="entry name" value="GINS_A_psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21696">
        <property type="entry name" value="GINS_B_Psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005339">
        <property type="entry name" value="GINS_Psf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056783">
        <property type="entry name" value="PSF1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914:SF2">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914">
        <property type="entry name" value="PARTNER OF SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24997">
        <property type="entry name" value="PSF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="9">
        <location>
            <begin position="56"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein PSF1 C-terminal" evidence="10">
        <location>
            <begin position="164"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="24045" checksum="8011307A164CC3D2" modified="2025-10-08" version="1">MYGDLGNKLVHHAKRAQNLAHLPPYQTELVRAVTREVRDLEKDLADMLESFEGGFDPHADQAKSCTMLVNHLSIRRNKRCLLAYHRTRTDKLEELVWKGYDLVDLPGQQVSSNSGSNLAATDTSSSSLSPQEEDYVRQYSDLLAAYKGQWTDIDLTGSLEPPRDLFIDVRVLKDAGEIQTEYGAITLTKNSQFYVRQGDVERLIAQGYLQKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3J9</accession>
    <name>A0ABR1X3J9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004952</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM170 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672885.1">
        <property type="nucleotide sequence ID" value="XM_066809267.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042327"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019334">
        <property type="entry name" value="TMEM170A/B/YPR153W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22779">
        <property type="entry name" value="SD17342P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22779:SF6">
        <property type="entry name" value="SD17342P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10190">
        <property type="entry name" value="Tmemb_170"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8489" checksum="D9F078A4A217B5D9" modified="2025-10-08" version="1">MQIGKRRTTWKYIWTVPVIYALIAGIEALFTGTVTGVVVGAVYLNGNFVLSTWVPFIWGWINVLVLVVSSFSIQGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X434</accession>
    <name>A0ABR1X434_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673016.1">
        <property type="nucleotide sequence ID" value="XM_066809398.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042458"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="113" mass="12149" checksum="50AD44DAC13A3846" modified="2025-10-08" version="1">MSGLLDPTTASFDIVSVILKQTMQKMNTTLSAVVDGVCIVAAGIATESGWFDEDGTGSAEACWRRCTCGKWIRRDNEWSGMLLACDIPEDAEVQPTATASVVNEVSNCQETLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4K4</accession>
    <name>A0ABR1X4K4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673216.1">
        <property type="nucleotide sequence ID" value="XM_066809598.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042658"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.20.20">
        <property type="entry name" value="Receptor L-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036941">
        <property type="entry name" value="Rcpt_L-dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="473" mass="50382" checksum="BF5278AC418525A4" modified="2025-10-08" version="1">MVKRSMNECNMGRNSPTAIKSAVDAEALARGCSTVEGDLTISAGASGDDGIRLDGVKSIDGGIHIQDCPNRCAGFTAGTISSSTLESVGGDIQISDVGGLKSLLFPALREVRGKITLENLVELQSLDLTNLKSVNESFIIAGAPELANLTAPPEGFDVTGDPARVRVWDVGLGSVDSFLIAPSNAHTRDISVSRIPNVVYAELATSNGGTVAIEGNGHLTLGLGNFRNISENGLLMPAHIETLNVSGLSDIRWSSSNSQSRPGEYYTLGALSVRDNRLLTSLPMFWEGIDSLEISRNDALAELAFPRSPEAARAVASSLRNISIRENPKLELGTTAEDGKWNGTVATTSWIWPTVDLETLMLSGVVHDTFFRPLEKIHGLTTSSSPNPAKPRVLDTFALTSTVAAFHCGTIDQMRMHGVFVGGYTCNGNSVDMVPPHHNAAVRARGVFGEGRKMMALVVSMLWIVLGRGWLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4S4</accession>
    <name>A0ABR1X4S4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005360</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673293.1">
        <property type="nucleotide sequence ID" value="XM_066809675.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042735"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="43"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8090399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="474" mass="51511" checksum="BC9444D3A1CA1036" modified="2025-10-08" version="1">MSLRVASESVVSELERGGLEEILSPADSARYSKRVSSYFSLTAQKKPFCFVHPKTTEQVSQILQALVANPDARFAIRSGGHVMWGASNIDDGICIDLGLQMNRTSIDKENRTVSIQPGARWRDVYKALEPHGLAVAGGRSGGVGVAGMLTGGGISWYIPRVGFCGDQLVNAEVVLADGRVVHANADENADLFRALKGAGGGTSASSRASTCARCPTTGSGRATPERSADHVAAMRRFTDDSERFPDSSYIVLWNYEPSRFEDVVITTFLANTKGVENPAELKQVCDIPPMARDLRQTSLHDFAVSMDQPMGMHNYWHTTTFLKDERIISKAVSLHAAAVSKIQAASQTGRFSSLCLFQSLPHYYGRLGAERGGGNVMGLDRALRGAQRRHAADEDGTVRGVGLAAAREFWEGVEAFAREVGGFVDWTYLNYADRAQEPLRTLRDPGEVRRTAVKYDPTGVFQTRAPGGFKISDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7M1</accession>
    <name>A0ABR1X7M1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673429.1">
        <property type="nucleotide sequence ID" value="XM_066806133.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039193"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF6">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="151" mass="17174" checksum="F564DDD5D9E1A4B7" modified="2025-10-08" version="1">MEKPRYGQAHPTIILIFSLKILAFRWTSYPRIRLYGEPKASEIARQIINKPALGVVWEQKTCVEVRWPFLAFPTTLVALTTMFLVVIIVQSARDTGTTNSWKSSLLPMVFHGFSMNGHYWGDVDGDVGLGNLRDMERVAKKTTAKLHLVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9I4</accession>
    <name>A0ABR1X9I4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_002445</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674056.1">
        <property type="nucleotide sequence ID" value="XM_066806760.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039820"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045680497" evidence="10">
        <location>
            <begin position="20"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="97"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="12">
        <location>
            <begin position="175"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="544"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="68"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="475"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="586"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="475"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="601"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="547"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="561"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8092084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="720" mass="75115" checksum="C61EAD21B489697B" modified="2025-10-08" version="1">MLWSNPVVILAAWAGLSAAHNADAAYAGHAAPRILGGRQFLSELKSRKTLAQDTSQFARAVPAAAAVGARHNHDSAGGADEEAKPQEAKLQERQNKSGRCGAGRGSCAAGYCCSSEGWCGSGLDYCTAPDCQLNYGPGCDGNKKPSGADTSGIARPKLGKVQYGGVGVYDCVNKGDIALTFDDGPYNFTDALLDKLASADAKATFFITGYNLGKGAINDPQYPWRAAIERMAAEGHQIASHTWSHQNFSQMSTTQAQNQMIWNEIALNDILGYIPTYMRPPYSICERACQNMLSTLGYHEIYFDLDTEGYLHDDPRQIQTSKDIWDDAVEGSDPCQDSYLQIEHDIHYQTVYNLTDYILDSLFRSGYRSVTVGQCLGDPPENWYRAGSGAVPAYDFTTREPTGTWACLKPTSTTTRTTTTSTTTKPTATPTLVVSPDGACGTGVTCQGSEYGNSLLLAPLFQVVPRMAGAAPRSTTAAAAASRSSAPAVTPTTPSPADSPIPTTSPTKLPTGPGAGVPDSPLTTTTTAPANPPAPTSTQKVSVDGDCGGDITCEGSEFGNCCSVHGWCGSTPDYCGEGCQPNFGSGCQASEPPSPPPPFPTSTTSTTISTSTTTTSTKQSTTSTTTSRPDSSTTTSTSTTPTSTTTTTSSSSSSSSSSPLPPRPTALVPSVDGSCGPGTGYTCEGSRFGVCCKRSDGRCGGLLLCGVLNCQPGYGLCVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9Y8</accession>
    <name>A0ABR1X9Y8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674200.1">
        <property type="nucleotide sequence ID" value="XM_066804427.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037487"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="146" mass="16418" checksum="41E6BA72A0489ACE" modified="2025-10-08" version="1">MAKPLLSPHLLENTGYTTADPAKTGPNGSNKALYTPRNTAREFKEQVRLVNLLKEYTTTQRQLFRKVRKAFDEKERQVEALQAQLEAVRPRKRKKVNLSPNSKFATIEDIQRTQLAVGEAENSLNEESDSDNSKAGSCIVVTVRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAC3</accession>
    <name>A0ABR1XAC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MHYT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674396.1">
        <property type="nucleotide sequence ID" value="XM_066804623.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037683"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005330">
        <property type="entry name" value="MHYT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35152">
        <property type="entry name" value="DOMAIN SIGNALLING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G11310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35152:SF1">
        <property type="entry name" value="DOMAIN SIGNALLING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G11310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03707">
        <property type="entry name" value="MHYT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50924">
        <property type="entry name" value="MHYT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="MHYT" evidence="3">
        <location>
            <begin position="20"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="776"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="786"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="854" mass="93543" checksum="23B3F3ADECD5619B" modified="2025-10-08" version="1">MSTPDELLQQYQGQIVPRSFNAGFVTLSYIISLIGAAATLELMNRRTSRNGFFNHFLLVSSSITMGGIAIWCMHYIGNRAIELADGQLELQIAYSAGFTALSFFIPIMVLLLAFVAAGTNQVSWYRIGGGGSLAGGAICGMHYLGNASIANFTCVYSTANVVGSVLIAMAASTAALSLFFLFRASWTGSWWKRGICAVVLAGAVSGMHWCASMGTEYRLDRLNSGTNPLSRNTTVIVVICLSVGASLTLAATAIWTAHVMRKTATKAQQIVLAAAVFDRAGRILVTPDGLLPSEKVTDTYIERTHDDVFNVANPLFHWMYRVSRNWSGVSGLIDNMADHLAGLPRNRKDSRARLIDEDGRLVDNYDVVFRELFCLAAQGLAEKTREQLANVGILWDEILPYRSETATEKSMEDAAEKGEGWRSRHEYSRGSLMFLVRRLDKSRDVEKLEAAGYRFADVSQVSHIISSSMQIKSQNVDSKLMDMAAFAEEKTMMEPGVHMGFFGVQARVGGGFDIVVRRGARNLLPTVQMSEEPLEPWQLDFVRRLDGLRVTTLVSNLKESKRVTPALSLFAIKTAKSVEILRALVKNPIFDEATLTARVVQVPCRAPFGSSSANSCTMISLKVVIPIHVNVLSPHCDLMPLSFFKVQQLVYKDSPQHIDFARSIHRELAPIVNARNPHATSPSSRRNKFFRHPISSASDHSVNDHGHSIPTKTRTKSIAASTSSASTLLWTKVEAERRLGDTPSDRSLVPKTDSQEPSALGGIMVSQEIKVVREVERAAQSAQSESKGHARGDSSKKHASDSSVMEMQPVARRDPEIHVGLKFGSATIESHKSGEAVSFVDDLFAVCVGNRHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAE1</accession>
    <name>A0ABR1XAE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674315.1">
        <property type="nucleotide sequence ID" value="XM_066804542.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037602"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="358" mass="39104" checksum="D9251AD9A8A8C212" modified="2025-10-08" version="1">MSFMLCLNYRTHPRQVVSLSPTGLGHLVLPASLADFGHGVSKGLNHHLVVQRPDGLLDLALVLAPPVRLLDAQVLHPAVLLDGLARHVAHPGLDHGHDPAERGRYLAPRPVPAEDLPRVGHVVVRAVDRQLIRPLRRRLVGVQRQGPGRARPVERDVHRHVEAELDVRDHDFAARGFVLGVDAAVVVVERALAVARTPEPRLRQHGEREARFGILGHLVRRRLGRGGQVPLAEVADHPGERPVFEHVHGRVRARLLHVHGDAPAELGALRAFELLLQGGFREAQPQPLPFRCLGDEVSPRNRLDGLLGLLCVRAGLGGRGNATGDRLAHVGVALGAVGLLRRIEEELPVKHDDDVVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBW2</accession>
    <name>A0ABR1XBW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[histone H3]-trimethyl-L-lysine(9) demethylase</fullName>
            <ecNumber evidence="2">1.14.11.66</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_000768</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:60200"/>
            <dbReference type="Rhea" id="RHEA-COMP:15538"/>
            <dbReference type="Rhea" id="RHEA-COMP:15542"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="1.14.11.66"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the JHDM3 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.66" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674856.1">
        <property type="nucleotide sequence ID" value="XM_066805083.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038143"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055500">
        <property type="entry name" value="DUF7072"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003349">
        <property type="entry name" value="JmjN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF7">
        <property type="entry name" value="[HISTONE H3]-TRIMETHYL-L-LYSINE(9) DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23258">
        <property type="entry name" value="DUF7072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02375">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00545">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51183">
        <property type="entry name" value="JMJN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="JmjN" evidence="8">
        <location>
            <begin position="69"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="9">
        <location>
            <begin position="309"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="561"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="128"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="492"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="865"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1069"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1199"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1253"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1298"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1344"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="879"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="950"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1014"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1096"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1111"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1199"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1213"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1261"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1367"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1377"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1399"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1426"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1456"/>
            <end position="1466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8094083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1466" mass="162259" checksum="C961EFCAC4581994" modified="2025-10-08" version="1">MSVEAMAQSAPEQPQIEVASESTNTAEKHSPKPHLDGEEVKKEESDATAQEEEQDDIGEITPAEWFGTVPVFRPTMHQFKDFKKFMTKIDSYGMRSGIVKVIPPDEWKNELPELHDLVKQVRVREPIKQDIMGSNGTYRQRASTPARRGERRAQAPPKPRTSTASGSRGRGRNTRGRTRRSIIKEDNADEEDRPMTPMSPKPGEGVLESVENDPGAEIDEDDEPVPMVGRMGGSRQAKAKTQSTSARRKYAKREASARIDEEVFRDWDYRMDISDYTPERCEELERIYWKTLTYAAPLYGADLPGTLFPEDTTAWNLNKLPNLLDVLGTKVPGVNTAYLYLGMWKATFAWHLEDVDLYSINYLHFGAPKQWYSISQGDARRFEAAMKSIWPTDAKACDQFLRHKAFLISPNHLQQYFNIKVNKCVSYPGEFVVTYPYGYHSGYNLGYNCAEAVNFALDSWLPMGKIAKRCECAQAQDSVWVDVYEIERKLRGEETDYEETEDEEDDEEEEEDEDETDLAASQSHVVKIKQPGRKRKRALKDKGERKAKKIRLRVRVKTQVEPPCCLCPNNLLDAELIPTDDGRKAHRMCALYGAETWIETVDGSEVVANVANISKARLELKCLYCRSKRGACVQCSHRKCARSYHATCAAAAGVFVEDGEVPIFGEDGTEYKEQAFEFSCRFHRAKRDRKLDGPALEECPKTRKAAVALKRGDIAQLQYYRGEIFAGVVVENRHDEQTMLVEIIPNGCEAYKTYSNIETPQLTMISDRVEVEWKWLLLPDAADYHLPKASPNAIPMPTSRKAKAEIKATKLATEELPRADEPFVEGCTWAEFHNTTECTNKAQAKVDLSKENQIWPVHNYKSNFLETIPKPPPPPASQPRKSYTPTYPLQPGQASANGRSEKPYQYKPKKPVPPLASPNAPIPYTNQSFIPNGRPFPTSTSTFAVYSSYQPPPPHTPQPSARPPHPQQPTPKPYTTPPSAPQASALPTPHPTAPSPAGHSYTPQSAPAKPAYTPQGTPRSMQLPKSTHQAAHSRNKSLPFGSDPRFRTSSSTYASARYDFNSSSPFSFGFMQPPGLGPSPSPQNGQLFQAQARARSLSTASANSLNTPMTSSAIRPSSSASSQGMPGPPQVGRLPPITRPAPPSVVQKYAFFQVHHNRDSTKYRTPYAPWGGFTNGYEGNLRAHLMKSPEALFTMQRQPTGNLATPTGSRYESSNGPGSSVSPGVSQPHPAHNATGAAVHFPADQYIANHQLPAAGAGNGDATTSEQSGLRTPNGSWNPTSIAAQLHPAIRSHYAAMLQRKQAQPPAPVQNRAPMVASPPAYTQSQTLPQPVQYPQAEQSYIAHCSPGLPQGQQSPMHGQTAGPVYQQATQPNTMATLPTQPQSQQPQMHTQDSYLHKGSPSSVPAVPSSANPGPTPPLQIGHGYQTPTSYTPPVSTQAQPVAHKQTFIPLLGHGSKYRRLRNQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC28</accession>
    <name>A0ABR1XC28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674973.1">
        <property type="nucleotide sequence ID" value="XM_066805200.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038260"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="8975" checksum="84FE2149F5A6FBB3" modified="2025-10-08" version="1">MAVESVGEPERGWRGLNAALRHYGIWPAMGPLPRGGVFAGKTCRVSFSSDLNRSRSGATAPLRRDSMLRECRHKSKHRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD98</accession>
    <name>A0ABR1XD98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Subtilisin-like serine protease-like protein PR1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_001355</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675443.1">
        <property type="nucleotide sequence ID" value="XM_066805670.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038730"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF58">
        <property type="entry name" value="ALKALINE PROTEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045122534" evidence="7">
        <location>
            <begin position="17"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="144"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="391" mass="40391" checksum="B094D8B8870FE56A" modified="2025-10-08" version="1">MKSFVVLFTLPLAALAAPILEARAGASVIPGQFIVVLKSDSTQGQMESNLDSASTILGGCKPKSSYYFGSFKGYHVSASEDLIRSIAALDEVTLVDYVEPDITVSTNALVTQTNAPWGLARISSRRRGTTSYTYDNSAGAGTYAYIIDTGIYLQHPDFEGRASFGATFVSGDSSQTDGNGHGTHVAGTTGSRTYGIAKRTNLIAVKVLDSSGSGTLSQVISGIQWAVNDMQNKQRTGRAVANLSLGGGMSQSLNAAAAAAVRAGLFMSVAAGNENADASTSSPASEPSVCTVAATDSSDRRGSFSNYGSLVDVFAPGVSIVSTWNDGTTRVLSGTSMATPHVTGLGAYLLTLEGARTPSALCSRIQSLATVGVVQNAMSSNNRLAFNGATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDF5</accession>
    <name>A0ABR1XDF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675503.1">
        <property type="nucleotide sequence ID" value="XM_066805730.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038790"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="125" mass="13911" checksum="363ED0FE05274957" modified="2025-10-08" version="1">MEIDTDTETDVGTSTDPSDLDEAKVPESPSCLLTDVSNYLSVHSQLEEDDTSVTVVDSDAYSRTSSMEDLYGWEAELDRKLGCGMSNPVQVCRCNHFEYRRADGAKRSLLHRVFNLPTSRRGSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDI2</accession>
    <name>A0ABR1XDI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001379</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675467.1">
        <property type="nucleotide sequence ID" value="XM_066805694.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038754"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21552">
        <property type="entry name" value="VEFS-box_ctSUZ12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="271"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="325"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="454"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="455"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="751" mass="83676" checksum="EAB6A59D51B2B1EF" modified="2025-10-08" version="1">MAATTPYKRDSPFLHRIWKTTIDFVSSSTNGEKPATGDQSPRPAKRRRVTDDSLGMNGFASVPALFQQPPPADSQRVLRIEVLRIWRNDGPKPATNGMVNGGSPVKKDTPSIRARCKITIFKWLAGVEMRPLYCDSQMCTIKEFCGVTGVCEAVRIHLPQPFEVAAEKLYVERNDNQGFDLDDCYFILAELESFGDPNWPPRYLLHGQESMHTPSSSPRKWSLQSQIKYAYSKGRVASQVRLRRGSGDTARILDPFWMDMDLRWTSSTIVGPLPSTESASPPDIKDSSLNGALEPLTNGHVNGRAETLVNGQLGDDADGLVDDEELEGEATTPSRPLRNRGKPQTYNLKKLSDKARGKEPKERKKRKLGELSADAAVVTWHLPSGALCTLDSWTCIHCFATHLSIDQLKMHMHVHREFKYAFDHSTRTGWRIAITNHGQQTPKSIRSYDLFEPISADEGESDEDEDESPQKARSRSRPKSISQLPKQVKPRETKQWIPQTSQDLYDRLSKCRLEPGSRVDEPQIDNSWLLQKHRDIIKDYSDVHPDEKEYAAEWDAFASREKATMAPHLQDVYLDFVREKATWIASTQNRMNEAMKHLAYLKARDALSEDTVVQALALARQARSTARVESSELRSPATSPKIKSRSGCNVCGLSISGPSTLICSNLDCDQPMYHHDCIRDDAKIPVERGLHWRCNECYDKEKETKEAVAAAIEAPAPAATDSSATVAAAAADTATATTSTAATTTTATAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEC5</accession>
    <name>A0ABR1XEC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675745.1">
        <property type="nucleotide sequence ID" value="XM_066805972.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039032"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="95" mass="10507" checksum="E1381F5FE03A3304" modified="2025-10-08" version="1">MSSISASGRGSRHTLLNPSHACTRTTNLADFIFEGATYTKPTTKPTFDRVNAAREPRDQRHGPPPEDDRTSESSNTPNTPCSRREVPQLPRSARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTG1</accession>
    <name>A0ABR1UTG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660804.1">
        <property type="nucleotide sequence ID" value="XM_066818616.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051676"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="579" mass="66097" checksum="EBAB246156C61AA4" modified="2025-10-08" version="1">MPVLQEQMDILSRAPWLRPRGDSSVLEHLDAMSVFRRKNWPLNEAAWEKGKLIGNEEFNHIFAEFAGLDRRGPPRDTFEGRELVNSSVNSVLRAARALLISLDDINIPLESLVDEKSRPTCVDRPISDPLFLSGTEKRPGTLALKAYLGGPADESKSNFPLDFSQTYAGEKRDFGVFEDPSAEARADLEREKTNAKRQALSSANKKEPTPSSRTKQPSTGGVDTAGGPIQSSDFYNYTIADADADITDLIQKTSGLESRRGLTTPVVGIPRDVLGKYRSTLSPWFEKFEWAREAIQEAPRPDQHLAPLEAEMAAQREYIISARSWGRYNYGKLKTLKCTTIFLRYLRCLHTRLLMVARPNDDLLQARVDRLADWILHEEVWNDFNQFSLARIKANSNLRPRYTAELAEREEKIEDWRNQILALEKAIADKKDAKTGADTEEAETTSSTTEKAPVATTAEAATQENEKEEKKKREEEEDAILDTILDKETERVLDPSRYAARMRRSTFRPTRKRYEYHMEDGKQVRVEKKPEDKQPEFAIFAEGGPPGYKELPREEVYDKLQYMVILTFWRVLQAKLHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVH7</accession>
    <name>A0ABR1UVH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_015038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661540.1">
        <property type="nucleotide sequence ID" value="XM_066819352.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052412"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="60164" checksum="2832B82980261423" modified="2025-10-08" version="1">MQNLPLEVVDSIVHFLHAEPVGDVDWPLRPSPLAPYASISTPFLEAVQRRTWRSLKVNSQEDLDRCARYLLCGRRLSYLRQLSFSISLPAIDKAKAQRFERPAETKAVSQVFGLQLRRLFRMLQGSEANVQLALPNVTHKFADVGHIRPIGQINEIECGLGWCRHLRSRITLLQADELPTVHSVRQLSFGIWQRSPDPRVQLEIAARMPDLVELNLAVDGTELRYPGVLRKDRKSLADALAKYSEQTMQISRAALAIPMEDVIIDTTMAMPNLTYPLAYDVLGTSLRVWSQRLTSFRVHGVFDGALFWPQAHEDAAVNRPEWRNMQNFDVHLELSTPSGLWYFMPKGDPSYGRPPRNPAEDPEDMPPMFIDDEDDGSADPFDQEAELKYSSAGGVNDDVRTRNAPQEGTMEPLFSAWARALACMPSLRSASLRFRVEIPICDEMDDEEYVSIDDWEVFYEAPHEHNQGAPWYADMDAAERASRRLVFHNTGGWRPREDTMDRLQETGSESWPGTSMVVLDVNEMCKIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXP8</accession>
    <name>A0ABR1UXP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arabinanase/levansucrase/invertase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661425.1">
        <property type="nucleotide sequence ID" value="XM_066819237.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052297"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18621">
        <property type="entry name" value="GH32_XdINV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 32 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="5">
        <location>
            <begin position="36"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="6">
        <location>
            <begin position="462"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="608" mass="67006" checksum="5350357E36D42D9B" modified="2025-10-08" version="1">MASTNPPIDADVKVDTELRGQSINNDEFRRWRPKYHLLAPRGWVNDPCAPGYDPVNEVYHVGFQWVPAGVEWNNSISWGSAVSPDLVSWTVRNRPSLAPTPDADKLGVFTGCLSPVTAKPGAITAFYTSVTKSPIHHAAPYAPGQELLHAATSSDAGRTWTRYEGNPVLSGPPAGLEVTGWRDPFVAPWLSMARLLDDPPATLYALIAGGTRAGGPTSFLYRLAPEALYDWTFVSTLGTMPKSLSASDDRYDFGSNWEVTNFVSFPDPDSPAAADAQLDFLLMSAEGMAAETTGGGGVPPSGQHAEFRRDHKQMWLCGKLRQPGQQEQGQGQQQPVEMAYRYGGFLDHGCYYAGNSFCEPKSQRHIILGWLVEEDLPLQRRQAQGWSGMLSLPRMLKLQRLENVFEPDDSKMEKLKSFGVHQTAPQTYALTTLCAVPAGRLQQLRRNHQSLAPQILLPTTTHPETESVGLVLQHSKDDPNTRTIITFHPSNETLTITRRHSTPHSDINTSEETAPHTLYKFLDPSITPSGDDGSSTAPAARTEPLTLRIFFDVSALEVFANERTAISTRIYPDSGPCYRISPFVKGGQCNILQCDYWEMAPNVHMAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1V6</accession>
    <name>A0ABR1V1V6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661923.1">
        <property type="nucleotide sequence ID" value="XM_066816231.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049291"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619:SF3">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="388"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="596" mass="66570" checksum="E263C87A40AA0B5D" modified="2025-10-08" version="1">MATLANPNVVMTVGHDEVVEFMETLEGDTHETLIFRGQERCTERDYEGIYADYRKVQKTFFQTANACLAKLKLPPMEVSDCNGWEGIQRSMETACAALEKVSSHDKDLKGVAGKTKKAFRSLCSKAGAGKMFSQLIPNDTFGSIIGGGLNVILTCMEQAGVHRANVYKALEKLPRIIEDSLDWTRLASQNATVHKRMAKLYTEVCLTLDHILHWFVLNSVVTGAKRLLNPSALNTALQDRVAEVTLAAKDLKSKATQVMWGQVNDMRDTQELVHMQTARTNCQLDELVADIENIKQLAARYASYDAMYKMVQGNLESLLQDDLKRLLLENTREPLSSSRSITAKDILEELQYDPALIPQDIEALLRLSLPSNVSVPLGRNRVHAIQRSPRLRVWLSDDAPYLYLLNGGAQAAADASTSFVMAKIASTLLEQQRQRLRRPSSAMEVIVLAYFCDQHRNYYRDAAASPSELAMSLLLQLIDRYSGFSSTTLQNCLDQTDPENIHSICDSLRFLLEELASDAVVYLVVDGIAHFTAPQERMEGMQEVVELLVEVFRGEVSATLKFIFSSPTRSAFLESLFEEDEILNIPRDPPPANGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V298</accession>
    <name>A0ABR1V298_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N(6)-L-threonylcarbamoyladenine synthase</fullName>
            <ecNumber evidence="1">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N6-L-threonylcarbamoyladenine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_012059</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="9">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662066.1">
        <property type="nucleotide sequence ID" value="XM_066816374.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049434"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24132">
        <property type="entry name" value="ASKHA_NBD_OSGEP_like_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01446">
        <property type="entry name" value="Kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034680">
        <property type="entry name" value="Kae1_archaea_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF14">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Gcp-like" evidence="10">
        <location>
            <begin position="74"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="120"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8065312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="351" mass="38068" checksum="48C7064F79230C69" modified="2025-10-08" version="1">MAPLYALGCEGSANKLGIGVISHDPATNKTKILSNIRHTFVSPPGTGFLPKDTAAHHRAHFVSVAREALRAWAPPLTSVAVAARTLSLLWGLDLVGVNHCVGHIEMGRVITGADNPVVLYVSGGNTQVIAYAEQRYRIFGETLDIAVGNCIDRFARTLAIPNDPFPGYNVEQLAKKAFFEPDGATEREPVLLDLPYAVKGMDCSFSGILGAADLLAAQMRKQDALLASGGSLKEGEERITPEDLCFTLQETVFAMLVEITERAMAHVGSKQVLVVGGVGCNERLQEMMGLMARDRGGSVYATDERFCIDNGIMIGLAGLLAWETGFRTPFEDSTCTQRFRTDEVHIKWRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3C9</accession>
    <name>A0ABR1V3C9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662451.1">
        <property type="nucleotide sequence ID" value="XM_066816759.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049819"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF76">
        <property type="entry name" value="CHAIN OXIDOREDUCTASE_DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="260" mass="27805" checksum="EA04AF7FBC8765F9" modified="2025-10-08" version="1">MATSSNPDTPTLASGPSVSRCRLDLVGCVAVITGASRGIGRAIALNLALRGCSVLGTCTNETSLELISSVLDSEVTRSYKDTARQRPSRLRIKGLGTIGEMDVQEVQHSLLGNIQTPVMIVDELVRRRLFQPDSRIIYISSVRSKQPWSRQLMYAAGKSAGESLCRTWAQAFGGKEEKYQFMAGTTANAVLVGLTQTEAVMNCGPDMVAEFQKEFFPAQSIPRFGQPEDVADVVGLLCSAEAKWITGSVISASGGGIKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4A6</accession>
    <name>A0ABR1V4A6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012777</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662783.1">
        <property type="nucleotide sequence ID" value="XM_066817091.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050151"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="16"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="351" mass="38346" checksum="D7CA69177899D2BC" modified="2025-10-08" version="1">MDPAPSFARLGKGDIILITGVSGLLGSATAKQALQWGFRVRGITRDPSKLLELKAKFDSGFGEGQFEVCRVEDMTKAESYAPHLQEVSGILHIASDASFRPAPRETIDGTVAATVGLLREAAKVPPVKAFVLTSSRVAAFNPPPAGEHLHVTSEMFLDDAAEKALATPATDPDLPSLSYQASKVEGEKAAWEFYRKEKPSFAFNTILPDWVNGVPVNPRPGFYSTYTWMAKFYNGLYEPTSIFHIFTNPPSTCVALRDVAALHVISLAASEVNEERNFAIEDTWSAGDVVQAIQKVDSAWQAPEGCAEAMPRSDITIPNQRFRDLVQKYCGRPLIKLDEAIAEVVNTCRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4F1</accession>
    <name>A0ABR1V4F1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_012816</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662822.1">
        <property type="nucleotide sequence ID" value="XM_066817130.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050190"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045150">
        <property type="entry name" value="CYB561D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422:SF24">
        <property type="entry name" value="DOMON RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="13">
        <location>
            <begin position="68"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="277"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="349"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="484"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="530"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="614"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="631"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="654"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="745"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="761"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8066069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="820" mass="89695" checksum="5707CEC7DDA9BA5E" modified="2025-10-08" version="1">MAPTDALSAPGAVAYSSDKMSVGDGTWDFTKNDFLLPNLQGLPFDMMQYNGMGNRFSTVKQYHSLILAHGVIAAIVFLFIVPIGVMMARFHRGAPGANIRYHAYLQIFAILLATVVFVTGWFAVGPNRSLTNPHHGIGVAIYTMILVQAVGGRLVRSIRKHSLRLMLHRWIGRIVTILGMIQIPLGLTLYGSPKVTFILYSIWMAILLFTYFVLSYRHEGDWDERTIYGGRSEVGTGRSRSRYTASDVTEKKEHGWLGPLAAGAGIFALLKGRKDKKERERSLSRSRSRSRSRGPEVIPSRRGSTSYVDEKFTEKREAPHGGGFMDKLIGAAGVVGAGALAKRFLDRKDSRKHGDEEYQSVATDTPRRNRRPARSEYTESEFSDEMTNLTRSHRGGKPILPGPGNPTAMAAAMSAADRPDRPITPRPSHARPGDSRLDSTLDSDYSSYVSPSRRAREERDTGDSAGKGLLAGLGLGWFTKKLKDRREAKADADRLRYEEERRDGRHGSKYTGDGYDSPGRKPPRRYTAPAGTNTTMSGESDFSSAVESRPTVIGHGGPPMPPLGPRSTPMPVDMPPLPPDPHGVLHRDESVNDGYASASGRPQRRDSRRRRDGSAAAAAAAASASLLASEVDDRRRRDDSRTRAGSQPVSVKVKYHDDRDRNVTLRRLTEEEAAREHRNRRSNSISSASGGEGSSRRRYRRDSSANRTVTDLHSGRHGDDPLSAPTPAFAGGKRAKDSAYYSGPDHPPPAPPTGPPPMTPLHNNNTVSSIGSHGTWSAMSPSPGGPGGTGASNTTSAADRRRQRRMERRTGRPSGTVEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4H8</accession>
    <name>A0ABR1V4H8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">L-dopachrome isomerase</fullName>
            <ecNumber evidence="9">5.3.2.1</ecNumber>
            <ecNumber evidence="8">5.3.3.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">L-dopachrome tautomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phenylpyruvate tautomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_012830</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-phenylpyruvate = enol-phenylpyruvate</text>
            <dbReference type="Rhea" id="RHEA:17097"/>
            <dbReference type="ChEBI" id="CHEBI:16815"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="EC" id="5.3.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-dopachrome = 5,6-dihydroxyindole-2-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13041"/>
            <dbReference type="ChEBI" id="CHEBI:16875"/>
            <dbReference type="ChEBI" id="CHEBI:57509"/>
            <dbReference type="EC" id="5.3.3.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.1" evidence="9"/>
    <dbReference type="EC" id="5.3.3.12" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662836.1">
        <property type="nucleotide sequence ID" value="XM_066817144.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050204"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001398">
        <property type="entry name" value="Macrophage_inhib_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954">
        <property type="entry name" value="D-DOPACHROME DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954:SF6">
        <property type="entry name" value="MACROPHAGE MIGRATION INHIBITORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01187">
        <property type="entry name" value="MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="Tautomerase/MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0202">Cytokine</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="244"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8066083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="38648" checksum="B116E4A297CF1E04" modified="2025-10-08" version="1">MEQRPASSRGAKVPSSPRSKEPTVPATPSSTPPGTASAAADGLSFAQRKALSSRSSSKSSIVEGNHLLRSVDRPLPGDMIYRRKSQVQPALAKKKSAYYENEFAATRESNPAMDRVRNEAIVMAELKTNVIIDDEFSFITDFSYHISNRYQRPMSSIVVNVQHSMCIMFGGSFDPAYTLTIHALPSLVQPTTNKRNAALIQTHIQDTLGVPASRGYVRFEATPEANTAYGGKTVAGEMDDVDRNRKDGAAIDRTPSRAAKSTKKMLGVRSLPGLRPSSAMSMREEAKLPTPPSSMDDTPMIATTIPEHPPTPPKSEQEPEEKPAKVAVRKKSFVSSLFGGRGSTKDRRPKTSGAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4I0</accession>
    <name>A0ABR1V4I0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662859.1">
        <property type="nucleotide sequence ID" value="XM_066817167.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050227"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="171" mass="19833" checksum="147FDF06C0F05B60" modified="2025-10-08" version="1">MRRQKQYMHPSYADMQARWGWGKLGSVMAAHKGHNGDWSRWSVRPDGMHGRSPVKRDRRLANIPRLAQPPTVGNWHVEIRYRRIRGRRRPRLAEPPPRSANKNATPDRWQLWVQNRLLHQPPLSSMPSFVNWKRRQKQAERVARDGGNEHLIRNDAPPCIHAGTGELGDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4X6</accession>
    <name>A0ABR1V4X6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cyclin-dependent kinase</fullName>
            <ecNumber evidence="3">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_012062</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662069.1">
        <property type="nucleotide sequence ID" value="XM_066816377.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049437"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF233">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="1"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="299"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8065315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="440" mass="48907" checksum="1379A74CD8454619" modified="2025-10-08" version="1">MHNEKDGFPITALREIKLLKLLSHRNVLSLEDMAVEHHSKATDKRKRPIMYMVTPYMDHDLSGLLDNPSVTFTVPQIKCYLKQLLQGLQYLHEAHILHRDMKAANLLINNKGVLQIADFGLARHYDGNTPQPGGGGGESKREYTALVVTRWYRPPELLMHLRKYTTAIDLWGVGCVFGEMLVGKPILAGESDTHQLVIIFDLVGSPTEQTMPGWKQLPGGQNLQPPPTPGNLMQRFRQHGPLAVSLLKELLKLDWRGRINAVDALQHPYFTTAPLPAQPGEIPTYEDSHELDRRKYQDRKAALPPAPKGGAVGDGGFHGNHQSFSSGDGYGPPGGRANGGRHPLIRTADTAMDLQKEDKLRGEEETGTGTETEIGIGTIHSLILGCRLGCRRLRMAGMSIVIEIIVIERLCLIDELLRRADPMSTHIFPVIEWGKRRAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4Y1</accession>
    <name>A0ABR1V4Y1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CCCH zinc finger domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663009.1">
        <property type="nucleotide sequence ID" value="XM_066817317.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050377"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23954">
        <property type="entry name" value="AMO1_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="209" mass="22797" checksum="DB583F6C5CFFDC23" modified="2025-10-08" version="1">MRHPQQIRSDSLPNRVVGRSDSLPLPIHSAALRTRRRTPQWIRQAQQPQREQRHPPILSGQPMSNGTGPQAANPFGQPQLGNAGAAPAAGAAAAAKGAPGNPYAPNSTKQHPPYDSYANRVGAKLVRFKGQPVMYKDDATPGLRLPDGSFRKIWFPNGPPAYYRGTEPDDPATYTDAVKKAYADMHANGRFLGAMPDVPPLREDCVWDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4Z6</accession>
    <name>A0ABR1V4Z6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo-keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661827.1">
        <property type="nucleotide sequence ID" value="XM_066816135.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049195"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19076">
        <property type="entry name" value="AKR_AKR13A_13D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="347" mass="38366" checksum="6A29CCA01F4F38A6" modified="2025-10-08" version="1">MAPTFPQRKIGNDSVSALGLGCMGMSFGYTSNGGYDEAESLKVLTRAADLGITFWDTSDIYGPFTNEKLLGKWFATTGRRDEIFLATKFANYFVEGEGMKVRGDAAYVKQAIKDSLERLQTDRVDLYYQHRVDPATPIEETVRAMAELKAAGQIRHLGLSECSARTLRRACAVHPIAAAQMEFSPFALEIESGQTEFLKTARELGVKIVAYSPLGRGFLTGTIRSRADLDETDSRFQHPRFSEEHFADNLRLVETLARIAEEKGCTPGQLALAWVLAQGEDFIPIHGTKRVKYLEENAEAAKVELSREDEKKIRQAIESVGGSKGARYPPAMMSKCFGDSPELSTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V574</accession>
    <name>A0ABR1V574_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">C2H2 transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013102</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663108.1">
        <property type="nucleotide sequence ID" value="XM_066817416.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050476"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050329">
        <property type="entry name" value="GLI_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818:SF139">
        <property type="entry name" value="PAIR-RULE PROTEIN ODD-PAIRED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818">
        <property type="entry name" value="ZINC FINGER PROTEIN ZIC AND GLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="222"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="103"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="184"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="400"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="488"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="555" mass="62694" checksum="F945F67F2A75C094" modified="2025-10-08" version="1">MQLPTTWGRWQEHHQSSPEYGMLGHSGMMQYDSRATSSPTVQQPSVATQYMVGNSYSMPSVSSMTAPHYQPHNPFGFQAYPPSTPSPLVAPFRQFSDGRPTLRVMPISSEKAPETSYPRDSMHSNIESNTASPEVKHELHTPPQPARGQDSSVTLTPTSAKNEGNKFENNTFIDNLMRVVQSKLNNKSDDNSPEARYPSPPRGSRSASPEDVKPNEKHPKKYRCDVADCNQKFAQKTHLYIHIRSHTGEKPYPCNHPGCGHYFSQLGNLKTHERRHTGEKPFACEQCGKRFAQRGNVRAHMNVHDPSKRFYCNLDGCGRPFTQRGNLKVGFFAAILLTGVHADLCNPSQSHQNKFHTKTLMELTEKFATMSAAELNSLPKEERKVFDDFAIIYKNLNKGIKGRGRDRNVAPAVPRSHPHNGQSLAGPPSHHLAQQQHTPPMHPHMASGSVPQLPQLPHPAELQHPHHHGLPPHQHHHEGDYHSYVMMRQHQHHQQQHNNPGQQHHMMVGRNTRPYEMMDVDQESLSGSGATPSSTGTFYEEDHNRNLSFEQHRMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5A6</accession>
    <name>A0ABR1V5A6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UreD-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UreD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663138.1">
        <property type="nucleotide sequence ID" value="XM_066817446.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050506"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01384">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002669">
        <property type="entry name" value="UreD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33643">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33643:SF1">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01774">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="328" mass="36006" checksum="E27781DAEFE73CB5" modified="2025-10-08" version="1">MISPFPKSASAAGEGHIVVKLLPHDISALESITYQYPLKLISPTVKATQQSVVVFLLSYGGGLVGGDQVNLKIDIQPFARLSIVTQGHTKIFKPAIPGTITRQRLSVNIQDGAALCLLPDPVQPFEGSLYEQTQVFHLHGSASLCLLDWVTHGRAARGENWDLLKWTGRNEIWFKNQDTGLKDRLLVRDTVLLDGTSESAHPMPLRETMHGHAIFGTLILRGPLTQSLGEFFLGEFSALPRIGARDFRTAAEKEKGLEKSALESWRASRLQQEIRDGVLWSAANVRSCVVIKFGAATVEAGRDWIGSMLAQEASLQKNFGEDALLCVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5D4</accession>
    <name>A0ABR1V5D4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663168.1">
        <property type="nucleotide sequence ID" value="XM_066817476.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050536"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050149">
        <property type="entry name" value="Collagen_superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023:SF1112">
        <property type="entry name" value="COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023">
        <property type="entry name" value="COLLAGEN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="242" mass="25582" checksum="4AFBBC88D52C424A" modified="2025-10-08" version="1">MGVADPVACKGHKGCKDRLGQQSKGPKEFKAPKGSQVPRDFKHKANLAHLVPLAPLGKLVHRDRKDRPAHRDRKHTLALLVQTGKRADQDLLDHQEEMAEMEEKVATVALGLMVDQGRLGKQYDCLALSLWTPGPFGPPGPPGPPGPEGPEGIEGADGPPGPTGPTGPTGPTGPIGLPGLPGERGPYGRGERGYPGPRGDRGPRGPQGDQGPRGDEGPRGDPGRWQGWGAMRPRNGDHGYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6N3</accession>
    <name>A0ABR1V6N3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013619</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663625.1">
        <property type="nucleotide sequence ID" value="XM_066817933.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050993"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="10"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="35018" checksum="4FE0266901997288" modified="2025-10-08" version="1">MAILHSVPAIEITIHVAGELAVEYKNTDLGEGDLLSPLPVTRCYIESRDNAEFFIRLEVSKDYDWDSVAHDIGFEVVVDGKTPSEWVLSKGIASYDIVGRSLKEDGTVKVARFKFASITTVPLLTAPGSYLVEDADQERVKRDRTIVKGMGTIEVRVFRLGSSELPPRLTPSLSPELSPEVAEKALKGKSTSHLTSYGSAGFLEGYEVNPGLIEQDNGPIAIYRFHYLSRRALQHEFIVPRSLQKEESPEASDARIEAIKSESAQIKSEPEQLKQELSAVKKDPEVKQEESEVIMEHIPEAGVSAVGSADLPIDLTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6R0</accession>
    <name>A0ABR1V6R0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013627</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663633.1">
        <property type="nucleotide sequence ID" value="XM_066817941.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051001"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053007">
        <property type="entry name" value="CYP450_monoxygenase_sec-met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="506" mass="56976" checksum="838B12EBDEB3698A" modified="2025-10-08" version="1">MASILVSVIGTIAATYIFLYLLLHITQDRKEPPAIVTRIPFLNTYGIPIYTLRLPFSRIYIANDTELLPPIQAQWRTISFSVFTANTGEQLGMTKTSRETMERGLMDPDSFSISWPKYMQPAMAPGEDLDRMNKISIEAIADANQDLAAKGVGRVGLWQWTHDIIIRSTSKAVWGPQNPFEDEKVEEAWKIFEPGFLTLNIFPFASLLFPQILRARERIATAMVQYMRHDGPKSGSGLIRRLVEHHSRFGLPLEDIARSQIGIGFAVMSNTAPCALWLLYHIFSDERVLEDVRREVAKLVEMRTTTEEEEGEGRETATNVVDLSALQSSCPVLLSTFQETLRVRTLSPGVRMLLEDAVVDDTYFLKKGNLLMMPAMVQHTSVPVWGPDANQFNHLRFKDNPRLGRTAFRGFGGGHVLCPGRFFARTEIMALAALLVLRFDVVPAGRKWVEPTWKNTPTQSGFLIPDHDIDVEFRPRGPANLKWEVVFPSSQSASKVTLEDIDGTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7E3</accession>
    <name>A0ABR1V7E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662938.1">
        <property type="nucleotide sequence ID" value="XM_066817246.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050306"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471:SF1">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="61950" checksum="9FD2B73C107BDC8D" modified="2025-10-08" version="1">MLLDHNPWTYAAVVGMKYGITYIGLWCLVYFFFVAFAFGLKGISHPVSIVIEVYGLIEILWYFIWFLPFKARLQRPGMPMSPTTRAQRKKLIANILKNVPDVRLFVRKWFCYAHIDQIYRDNVKDWLAWALFARDSKDLSPEEWDELDEYVDEAQEVAGLDLPPGRADGKPMRLNLEPVEMYHRPLLWYFFMSFTEVACWAFLAVKGFTFYRQPRGTFFSIFPFRPMTLLAPKASASDEFSYFCRPHRSKTHRPVLFVHGIGIGVPTYMTWLPSIPKDIGVIAVEIINASNRICPEGVHPSVFARAVAKILRQQKIDDFVFVSHSYGTFMARPLLKHPKVGPKMNSMILCDPVAILMHLPNVAYNITRRVSVTTPEIEIDFGAGRDPMIAHTVCRRLHWPEHILFREDMAGRRTTAVVAGRDCVLDGPAVASYMYYGKVDQTSHADLKELEKTWDTWTGRGDIELMYLPDRDHGQSLLLPKLAKRICEAIATYCDMSKDPSTMEPKSENPRPPARPRSTAASARRPGYPWRTSRTTLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7Z9</accession>
    <name>A0ABR1V7Z9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_014069</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664075.1">
        <property type="nucleotide sequence ID" value="XM_066818383.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051443"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="17"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8067322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="500" mass="52795" checksum="727500C46241D40B" modified="2025-10-08" version="1">MKLSNLLLRKPPGYMLACMVCSFGGFLFGIDTGIIGPVTVMDDFKNYVGDPSPTIHGLIVSSILIPAAISSFFAGKVADALGRSHGIAIGSFVFGVGAALEAASVHIGMFVAGRVIEGIGEGLYLGTLLLTTLGLVTGFFTCYGSADIPSSFSWRLPFLLLAAYSLVFSVAALFWLPASPRWLTLRGREDEAAAAWEKLGVDAADREKILEQLPTSVVDGNTATVDASGSIALMDLAPGTRPANPAPPKKKKSQLLDVFASDARPRLLLAVFLMGMQQLSGIDGQAGLSSNESAFLASGVSALLIFAVTVPATLWADRWSRRANTIAGGLGMTCTMFLMGALYASDAVHAGAGAGRWVVIVCIYLFAVLYCVSWAVGIKVYAAEIQLPATRASATSVAHGSNWLSNFLVALVTPTLLAKTSYGAYFLFGGCTLLTALVCWGFMPETRGRSLDEIDLAFREKKKIGGSRVGVGAVSGVKQFAKALLSRRRVLRRMPPTVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8F2</accession>
    <name>A0ABR1V8F2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uracil phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013924</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663930.1">
        <property type="nucleotide sequence ID" value="XM_066818238.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051298"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="2">
        <location>
            <begin position="45"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="248" mass="27862" checksum="AF45CEA84722CA14" modified="2025-10-08" version="1">MSDQPAKRPQVGPTQCVGPDYRTESQKPVATVSTEIEYDNVITLPQTPQLIALLTMIRDRNTDRADFIFYSNRIIRLLVEEGLNHLPIVEQTVTTPVGRTYAGLQFQGKICGVSIMRAGESMEQGLRDCCRSVRIGKILIQRDEETSMPKLFYDKLPEDIADRWVLLLDPMFATGGSAIMAVDVLKSRGVPEERILFLNLIASPQGIKNFATQFPKLRVVTAFVDQGLDEKNYIIPGLGDFGDRYYTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAQ8</accession>
    <name>A0ABR1VAQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">guanosine-diphosphatase</fullName>
            <ecNumber evidence="5">3.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013785</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.42" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663791.1">
        <property type="nucleotide sequence ID" value="XM_066818099.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051159"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24040">
        <property type="entry name" value="ASKHA_NBD_GDA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF83">
        <property type="entry name" value="GUANOSINE-DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01238">
        <property type="entry name" value="GDA1_CD39_NTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8067038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="555" mass="60511" checksum="FEFD50F4F6A0F331" modified="2025-10-08" version="1">MRRTSVSLPTKQVARDPHEKPGRYDTNYGQHPHRGETGILEKLPPAGMNSAQKARWLKTTAIVVFLIFLFYYFSPRGADIYTGEVAPSTSKGQTPSDSSYGTDRCTKSVSKDKPIIQYVLMIDAGSTGSRIHVYKFNNCGSTPELEKEEFKMTEKSVGGLSKYKDDPIAAAKTLDDLMAVAMQTVPDKLKSCSPVAVKATAGLRMIGAEASDKILESVRNHLEKDYPFPVVSREENGVAIMDGSDEGVYAWITTNYLLGKIGGPDQSPTAAIFDLGGGSTQIVFEPTFKGAANGGMPEKMAEGDHKYKLAFGGRNFELYQHSHLGYGLMAARNSIHLNLIEDLAKGQTGNAWLSQSIVNPCINAGQSDTIKVDLGNDHGALGKGKIEVNMTGPATPAPAQCRSMAERILKKESACALAPCSFNGVHQPSLAKTFAKEDVFVFSFFYDRLKPLGMPDSFTLRELHDLANTVCGGEKSWEVFGSIPGAMEELRDRGEYCLDLNFMIGLLHTGYDMPIDREVRIAKKIKGNELGWCLGASLPLLAKNSGWNCKVSEIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGU6</accession>
    <name>A0ABR1VGU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010628</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664233.1">
        <property type="nucleotide sequence ID" value="XM_066814943.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048003"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="47"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="389"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8070425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="413" mass="46196" checksum="5F97758E64F2CE1D" modified="2025-10-08" version="1">MADTKSLIGLIGFYDNLDEPMPVSNYPETIIALAVTFLTITWGCVCFRLYTRFFIMYSPGWDDLFVALVLLSGTVGSICECIATNHGMGTHFIKMEKEEMATYLKYFYVSNTTYCMSTAFVKLSLLFQYLRIYREGKMRTACIVVMVITALWGAAYTFMAVVPCFPIQKYWTLTLPGKCYGFGSLNPPVFYAMYASSAAMNMTLDLVVLALPVPFYFDKNTPVKSKLGLVGLFCMGIIINFISIWRVASMVEHRAATFPTFDPTWYGPISIELATLEVNFASICASIPVFWPVLTARLDKVFVTREIKIERIHRFETVDEDAELNGKYLGDNGVELQPSHRTRSNSGNDGGIGGSANQYGGNSSHYLDEYVAAQVDPLSSMGKVELEISAQPVSRKNSRAQMLKKHRDRDGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIK2</accession>
    <name>A0ABR1VIK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011252</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PRP38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664857.1">
        <property type="nucleotide sequence ID" value="XM_066815567.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048627"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="188"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8071049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="288" mass="33155" checksum="66DD864ED38E76F4" modified="2025-10-08" version="1">MATHRADARQFLDERGSANIALTPNGLNPSTILEKAVRERIVESFFFKDQCFGVNEADIVDRVVRHVRFVGGTYGSAQKPTPFLCLAFKLLQLAPSDAILQEYLGFGGDKFKYLRALALFYIRLTRTAPEVYRTLEPYLEDRRKLRRKARAGTSLTYVDQFVDDLLTKDRVCATSLWQMGKREMYEDLDQLEPRVSPLGDIEDLLDDDDEDEENKDKDGDDEDDVEMLNGGDDSDDGARNSDDDEGEVKEDSERRDRRSSSEDRRRSEDRERSESRSRRRSRSRGEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJB3</accession>
    <name>A0ABR1VJB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665132.1">
        <property type="nucleotide sequence ID" value="XM_066815842.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048902"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="233" mass="26328" checksum="6F318961EE977854" modified="2025-10-08" version="1">MSGERSGSSYSPGMNEVSEEPNSHTLPEGSVDPCEARDGRSRGSEEILVPVLEDASAQLESLRDVLKAQCARHAKEIADLKQFLEQAHARNKALLAELAELAQKYGLKLKQTRVVYQGQYTHLLQKYETATSQPIFQAMTDERLKKMVEILRQNVKALALRCCPDHGIRWSTEEMEYVTDPDDPLLRVGMPVTPVSMQAYFWIILVREVFGKFLWAGGDARKLHDVWVRLTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VK17</accession>
    <name>A0ABR1VK17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sec1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665310.1">
        <property type="nucleotide sequence ID" value="XM_066816020.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049080"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="591"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="607"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="696" mass="76592" checksum="579B3C44ACA473CE" modified="2025-10-08" version="1">MASLRDRQIASLRKILNLNEVVQKEEDEAAAHANGSLAPVGPILTAEGEPIWKVLVFDDLGRDVISSVLRVSDLRSMGVTMHLHINTNRHPIPDVPAIYLLEPSPKNLENITNDLQRGLYTPAYINFTSSIPRPLLEDFAAQTAATETSEHIAQLFDQYLNFIKENTYWALNSAKTKDEELDHVVDRIVSGLFSVVVTMGVIPIIRCPKGAAAEMIAGKLDRKLRDHILNSKDNLFSSSARPSSSAGTPTSRPVLILLDRNVDLNPMLSHSWTYQSLVHDVLNMKLNRITIETPVEEGNPAKGTTKKSYDLTATDFFWEKNAALPFPQVAEDIDAELTRYKDDAADITKKTGASSIEDLQNDTSASAHHLKAAITLLPELRERKNVLDMHMNILAALLTGIKNRQLDNYFQMEEDVMKQTKAQVLEVIKNEEKGNEPLDKLRLFIIWFLSTEQEVSRAEWTQFEEALKAIGVDTTSLAYVRQVRATTKMTQLTTINNTTQPASQQGGSDLFGRFSNLSTRLTDRVKDAGVTLPGGFNLDSLSGALKTLIPVNRDLTVTKIVESIMDPQTASTSALAKTEGYMFFDPRSANARGTMPPPSALRSGGASSTPGSMPGMQGPGMANQPSFGQRRQGYTDAIVFVVGGGSMDEYGNLQEWIARTGSERAKKRAIYGATEIMNATEFVEGPLRSLGQEVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VK28</accession>
    <name>A0ABR1VK28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010859</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664464.1">
        <property type="nucleotide sequence ID" value="XM_066815174.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048234"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="5"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="47"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="118" mass="12425" checksum="9B77FB6D1FE6E946" modified="2025-10-08" version="1">MRTTLEGHSGYVNSVAFSPDGRLVASASHDGTVKVWDAATGQEKQTLAGHSGYVNSMAFSPDGRLVASASHDGTVKLWDVATGQERQTSGIGTVYSILSFNADSLFTLADIGTIFIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLK7</accession>
    <name>A0ABR1VLK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664551.1">
        <property type="nucleotide sequence ID" value="XM_066815261.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048321"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="313" mass="34642" checksum="92C57312A919AD77" modified="2025-10-08" version="1">MSSHRSSQSSGWSSSDNGSPKATMLNTGFLYGCGDRSGVYDETGHLWDALVLHKLVSDWPNMDRVIETCCPKCWSIGTSPALVAMRSRVLRYQRLGPEHAHSLLVMLYHLANQIVADPTPVLLELLAKWAQAVGSRYVTDATHLDRLQSAIWAKTQVLVAEDAVRSIKAYRSPADSPSVAKASGKREYLAAEFTRLERRDHELRRTLLKPWPVYLTGPLFALADRGIRYAAIFQTTEMDLVAFGQAFQAVSRKPHDYSIYAYHSKLVDAVKGLKLKTYELVQCTEAAGGNVTVRSREELRAAMAMVGGAEGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VNJ4</accession>
    <name>A0ABR1VNJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011682</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665287.1">
        <property type="nucleotide sequence ID" value="XM_066815997.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049057"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="559"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="591"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="640"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="670"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="710"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="737"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="767"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="795"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="9">
        <location>
            <begin position="12"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="361"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8071479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="840" mass="91650" checksum="E7BC594EE2FF0D6C" modified="2025-10-08" version="1">MSNRSQDKRPLTVIIVGGGIAGLTLANALQHAPADITFVILEARDSLASRLGAGIALVPNGSRVLDQLGVYADLEPGFDPIVDTGLIDIQGRPLLPERTDGAKLLGIRMSYPLALVQRSTLLHSLERHLRPGKGGHVLTGKRVDTIKQDDAGVTVYCTDGSSYQGDIVVGADGVRSKVRQEMWRASEEEGIGNIDVNKERKAMTAEYLCLFGVSGPVPGLGPGTSDDTWVQDLTVVAYSGERGKVFWFVYARMDRVYEAHEMPRFSAADAAAFAQKHLDVPLRPGGAVRFADVWKAREVETMLPLEEAHFEHWTAGRVVCLGDSVHKMTPHSGGGGMLCIETAAALANALCQLAAETNCSNLSKPKDSNGQGASKSPKRPTLSQIEAALRGYETGPHNLHRRAIENIKASGDLGRLSALRTLAQRLLVPYLVPVSLDTRVDLFCDMAVGAPCIDYLPIPPRSTKGTMLFNPSHGMGKHESRWKRAFVALPLVFLAVGFMKVVTGLLPVDNIRQVLDSGVYHPENGGASVNLVPGIYGISLVDNLSRIHNLEAVVAREKAFFLMLSFFADYGVWYVILLIESARRANYFSILAPAVVWGSAQTWGIAYVASFYRFLHYVLSPVSKFDALDMRLTDRTYTQIVLPAVAAAHYAVYLTGYLGPEPYRQIAGHLWMLFPLFLSLGQNVAVRFVLKPSTVSLDRLYSPTRDMPVIRWTILTLVAFSAAVWQYTLWCHDQPSIACVFVPALPISSGAELSLEAAYVELLKWDWAGFGASHFIWIALFAWDLKAAGMARVSWLVLGLCAAGVTAVGGPGAFLGLAWLYREEILAKRRHKDAVGPKTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUB3</accession>
    <name>A0ABR1VUB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPP4R2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665747.1">
        <property type="nucleotide sequence ID" value="XM_066813785.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046845"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015267">
        <property type="entry name" value="PPP4R2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487">
        <property type="entry name" value="PPP4R2-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09184">
        <property type="entry name" value="PPP4R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="498" mass="51570" checksum="F272548D44894B01" modified="2025-10-08" version="1">MMDIDEEDLLNNVAATGTMDYSMWPALLPRIVSRIEKIAHDDFPMPQMPSAPAATNVTSMAHHPATSDSEDTENFLAPLPSSPTEPPSTTSSQDTNKENTPVAPRSTAPTLPAAAPAAAEPLPPGTVPPQVTAMLNEITTTLTSTFPTYPPHSIQRLAELVLAPKHHYKSLPTYLHALDRVVHVTSGLNVYPLPPAVPDASSISLLPNGATDAILPSPWAAPGSDEALGGALLTPIPWLQHGSQGQGGLSPTSSQTDSSSAAGDRANDSEGELRTESTETIDGPNGMGSIETVTVTVNGVSSMGARVGVGVTQENSSAKNNAQAVSPSTTATLADDSPAASEAKEGVEEDAAAEPVSDRAEDERPHARGPEEIGAEDMGPQRESSSSANYGGGAGLDMHGIDVEAAVGRKATETRTSPDTASHGHPTAEKDDGDEMEGVESAAAFATEKARSPTPKREAGNDLEGTSKKLKGDPDKGTSPKEEEEAKANEEEAAKTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUE6</accession>
    <name>A0ABR1VUE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665815.1">
        <property type="nucleotide sequence ID" value="XM_066813853.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046913"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="161" mass="17950" checksum="01935F38D7459527" modified="2025-10-08" version="1">MRQDNDGHISTILEEDEEIDTTNTTDTAQAQANRTCQDYHPDDLKGKGEPSYTLERAFKHGKSASVGDGPGVYEMQPRGMSKSSPSKDKEGDVLIRQRSRSSSFGEGPSGSGAHATSSDSPVRRRQQQLAWQTSQYRPEEAHRKHSPQSWSWLIVLCFKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUM6</accession>
    <name>A0ABR1VUM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665867.1">
        <property type="nucleotide sequence ID" value="XM_066813905.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046965"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="45"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="729" mass="82896" checksum="66EC173BE2660360" modified="2025-10-08" version="1">MNSDGANMDNGTHTPGPPSRRPINQFRRFNNHAQFQGLWREWPELAVRLQNLPADVNPQTLRQVFQPLGEVVFIGVLPDDRDANKRAAVVRFSPPPQAAFWQNGYIIIDFSPQVKVPVICLNPRRPELIRSPVTGLEYPVDMKIRLVGLDFGFLSQESTMDVMRSIQYSADVPLVFSLSAKLNFKKLEIAFPCSIPKPSNTNPGDEMDDSPSPRQHRYKAVIRFSHITKIYCIRKDDGPEELPGRRDPDTMGEHEAWQRIGTIKYESNSKDEVTSLRRPDQFVDIGRWTTYRLTMDASNKSVWQKMKSALSDFNIQFTELSAKDFKTRPGAPSNLWNMIDAPTSGVASGLELLHNTNSVHLPFEIRYQLEAAISQGVFSEQSITLDFLTELAKLVPAPGPEVNTETEAGTEPGEIPHFLNNWRFMNRRRFNKARNLLEYVTDCRKRVYDPMSVFGNGNALTYTPGFNYEHCAWVRKVIVTPSTMYLGSPTLEVTNRVLRQYEGNIDLFLRVQFTDERTEGRLSADQDSEKNHHLFNRVFNTLRNGIRIGDRHYQFLAFGNSQFREHGAYFFSPTGAQSCDDIRSWMGNFDHIKVVAKYASRLGQCFSTTRSPKGITVDHTRIPDIEHEEWCFTDGVGKIGTYLAKDIAGQLKMLKKHGSPSAFQFRMGGNKGILVTWDDAKWNEVQVRPSQNKFTSLARNIEIIRPSRFSVATLNRQTIAILSCLGVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUV9</accession>
    <name>A0ABR1VUV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Myosin type II heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_009704</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665981.1">
        <property type="nucleotide sequence ID" value="XM_066814019.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047079"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01377">
        <property type="entry name" value="MYSc_class_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.360">
        <property type="entry name" value="Myosin S1 fragment, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.270.10">
        <property type="entry name" value="Myosin, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055914">
        <property type="entry name" value="DUF7491"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008989">
        <property type="entry name" value="Myosin_S1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002928">
        <property type="entry name" value="Myosin_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004009">
        <property type="entry name" value="SH3_Myosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF857">
        <property type="entry name" value="MYOSIN-11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24319">
        <property type="entry name" value="DUF7491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02736">
        <property type="entry name" value="Myosin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01576">
        <property type="entry name" value="Myosin_tail_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51844">
        <property type="entry name" value="SH3_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 8" id="KW-0518">Myosin</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin N-terminal SH3-like" evidence="12">
        <location>
            <begin position="116"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="11">
        <location>
            <begin position="170"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="8">
        <location>
            <begin position="745"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1134"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1642"/>
            <end position="1710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1732"/>
            <end position="1764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2257"/>
            <end position="2276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2381"/>
            <end position="2414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1193"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1419"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1835"/>
            <end position="1869"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1926"/>
            <end position="2038"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="2116"/>
            <end position="2150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1134"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1642"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1671"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1736"/>
            <end position="1759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="2262"/>
            <end position="2276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="263"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8075041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2414" mass="275439" checksum="0507A1D65C5A7B16" modified="2025-10-08" version="1">MSQRRNNPFARAGPTSPGPSPIGSIGVAGRPKSTIFSPGSPLSGKTTPPAHTRTQSQSSMSLGFLPPAINGTRQFRSDSRSSTPSTSTFAPSFIKTEDLRRSIDVVKGIEGENDFSGKRYVWLKDPQAAFVKGWVVEELGEGKILVQCDDGSQREVEAESVDKVNPAKFDKANDMAELTHLNEASVVYNLNMRYHADLIYTYSGLFLVTVNPYCPLPIYTNEYVNMYKGRNREDTKPHIFAMADEAFRNLVDEGENQSILVTGESGAGKTENTKKVIQYLAAVAHSDSPMKSRGGGHHSNLSQQILRANPILEAFGNAQTVRNNNSSRFGKFIRIEFNRAGAIAGAFIDWYLLEKSRVVHINSQERNYHIFYQILKGADQKMRNDYLLNDMGVEDFAYTRDGHDTIVGVSDRDEWNSLLEAFSVMGFSDKDQDSIIRTIAAVMHLGNVTVIKESRMADQARLAADAKDVAAKVCNLLGIPLEPFLQGLLHPKVKAGREWVTKEQTPDQVRLSIDALAKGIYERGFGDLVTRINRQLDRSGMGLDDSHFIGVLDIAGFEIFEENSFEQLCINYTNEKLQQFFNHHMFVLEQEEYAREQIEWKFIDFGRDLQPTIDLIELPNPIGIFSCLDEDCVMPKATDKSFTEKLNSLWDRKSNKYRTSRPGPKHGFILTHYAAEVEYSTEGWLEKNKDPLNDNVTRLLAASTDPHVANLFVDCADTEDDNGGTRSRVKKGLFRTVAQRHKEQLSSLMAQLHSTHPHFVRCILPNHKKRPKQFNALLVLDQLRCNGVLEGIRIARTGFPNRLPFAEFRQRYEVLCKDMPKGYVEGQAAAAMILGKLSLDKSLYRVGLTKVFFRAGVLAELEEQRDALIAEIMSRFQSVARGYIQRRAAYKRLYRTEATHVIQRNFNVYLDLCENPWWQLLIKMKPLMGTTRTAVEVKRRDEKIKLLNEQMQQEAENRQRLEDERRNCHTELVRIQQTLESERALALDKEEIFKRLQQREVELEDKLAGAIEDQERLEDQLDDLLDAKKRAEAEVDKYRSQLEQAAALIARLEEEKTSLDGRVGDLEAEIRAVSQKQADRSAQEKILEDDVRMLQSQLSLKDRKVRDLESKLLKSDQDSDVKLAAAQKELQTVKSREQQLSRENKDVQQQLSQLSKTSTDYEDLVRKKESELVVLRSDNKKFQMEQRSFEEQKKTLLAEKEKTGDRLREVQAEMVAMKSQQSQLQREAEDAKQLLQTRLSEDTQANQNLQLLESQIKDLKDQLYKIQMDLSRERQSRDDVALLAEHKLQSLKEEHEQLKEIKIEIEKELYLQQDKLRRTIEARATVEKERDEAREEIKRLRLAKSEAEEARLRAEEAGERIATKAAREREASLQRDLDASHERLRWFEAECEKLNHQVEDLNKFMIDSGDYGLKNDQARERLERELVTVKGRLTASENDNRALLNKIQQKGLEIARSSSRASEANRGQLISLQREKARLEDQNAKLNKQFGDSQLMIAGLEKKAEKLQLNLEDLNHKIAQETKSNRNAEKMSSQSTVQLAELNRNLEAERQLRSQAQTNVRTMQGTLDSRGKEIEELRAQLLRVLKAVDPEIVPPIPAEGGHDKIMSKNFEMIRKIEELQQNLRIQAAGRANAEAQLVEMRASRGEDMGTRPKLEETDPDEAPFNGSPVQRRPKLNGRKHSGATTPTRRLGNDNDAVQDSGRSDKTADILSFNNRQDLKTEVEELQNQLQLTQMQNRHLQSQLDRSTPTQEQDPFSESPSVRRVQKLEQANSRLHDMLDDSAKKVSHLEKSIRTGDLSLRDLQAKSHEEILDLVYSQEDSRRSLLHSHNDAVAELTDVKEHFEKMRRERASLEVELRDTKSDLQEMSLAREQEAAGRSHLLEDFAEIQIRLDAETSKLADVTSSLNLYKSRADEYFSKLEQAEISVLKATRAEQFAKSQAKEAEEQCAEMMAEKKSIDGTLEDLQRQNQRLEEKLEDLTTDHEAATQAKKRLQHELEDYRNQRAIDVEDKESSMEQTRKKYQAEFATLTKELDLAREEKLYKQSEITRLREELDDLRSKWDDEVLNSSTWSKEKARLESTLSDVVASRDEAVTAHNEAQAKVVSLLSQVRSLRTSVDDVTAERDALVREKRSVEARLEEAKAGLDDLANSESPALRNAASTDKVILELKSGLAQQEDIATAAVEKMRRSESLANELQKEIAVEREIGTELSKQKAALEKSLNEIQVRLVDLETKGYSSTSHDIKFLHKRIQELESQLEEQETEKSKSQRSVRNVDRIVKDMQSQIDRKDKQATQAAEDAARLRDKMEKLLKTIDELQASESTNQISARRAERELQEEKERALKLERELDGWKGLRMEKGSVNGSVRLSMSGLDGMRRSSAWMGDDTASLSGTGVEVPKRKSSINRAPSLTKGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUW6</accession>
    <name>A0ABR1VUW6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665907.1">
        <property type="nucleotide sequence ID" value="XM_066813945.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047005"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046459877" evidence="1">
        <location>
            <begin position="20"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="153" mass="16270" checksum="D7F83604FE0CE368" modified="2025-10-08" version="1">MQLSQILSLGGGLMALAAAQGITLTPTTVTRGGPTKTVYIPTTTTETETDTVTVTKISITTTCKKPTPTDCPKLTSTGTACRSCFVPDCTETVQTTKSCGCPAAVPTTTVNFPLQRSGLVRADRLQDAVPDRHGGVLRRERNGREIWQLAFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW32</accession>
    <name>A0ABR1VW32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutathione transferase</fullName>
            <ecNumber evidence="2">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010065</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666342.1">
        <property type="nucleotide sequence ID" value="XM_066814380.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047440"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF20">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE 1 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="89"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="256" mass="29380" checksum="970C7135D6AB5F79" modified="2025-10-08" version="1">MQPIRVWLTPPGPNAWKVVFLLEELGVPYEVKSIRFADVKKRPMIDVNPNGRVPAIEDPNTNLTLWESGAIITYLIEQYDTRHTLTYTSLADRHHLNQWLHFQMSGQGPYYGTSGWFIHLHPETLPSAIDRYTKQVTRVLGVLEGWLAEDGREWLVGDKMTYADLAWVPWNDRVDTVLVGVPEPEKLDAFPNVKAWHKRMTSRASWRRCMELRARLMDEQGLMPNGMPKGTMPEGVTSYSDYVAKVDAGEDPVFQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW74</accession>
    <name>A0ABR1VW74_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666387.1">
        <property type="nucleotide sequence ID" value="XM_066814425.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047485"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="140" mass="14836" checksum="5C646DFC0C78D53A" modified="2025-10-08" version="1">MLSLSFRTEYPSLEMIPDPMSHRPSTPSRVRAVPPRLPPGSSPEAPFGSPVRHLGRKGRAQAVGAEPLLVVGQMQRRRDDAELGLGVSDPKLGLGELAVDGEGGGAVFEDAVLGPLVSEHLVVDDGEAILGPLYHRFLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW99</accession>
    <name>A0ABR1VW99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010182</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666459.1">
        <property type="nucleotide sequence ID" value="XM_066814497.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047557"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="2">
        <location>
            <begin position="295"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase lid" evidence="3">
        <location>
            <begin position="400"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="525" mass="59735" checksum="78EBBF7586E07949" modified="2025-10-08" version="1">MSAGESALPDGEQDMPPDPILSAAPESKFTARKAPIGYRTEYRHKNMRELIDDETSDAPQTDRSGDTGADDSPDLAFEIVETYLSSGIIFLDTEEVESSQDSVVRELVEWGRIYWQLLEKQPMQHEGQSPRFPYQQIDGLIMADAKTAVIIKSSYDFLSASDLRKGGWRCSCDVCASTQSDGNEGNFNALFEDYHNIVCQVWEAGLLTAHKYLLRPSELLVFVFKTRAWERVHVTNLRGPEFDETMVDNLIMDDKKKRTLAYLAKSFARQNKADEPMSQPMRSADYVVGKGSECIAAFAKRPLMVLTSSDIGTDPKEVEGNLSKHFKNAKNWGAVLLIDEADVFMERRTTADLTRNSLVAGFLRALEHYEGILFLTTNRVGPFDDAFISRVHVQLYYPEFTDEQRQRVWQTFVSNLESDRKGYMRLSYAAKEYIRESKKSDLKWNGWEIRNVSCTLAFQTAVSLAEYDVKKDEEGTILVTDQHLRAVVELSKDFKDYLQELHSGDEDKRAQGRAERLDSFKGDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWJ1</accession>
    <name>A0ABR1VWJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666157.1">
        <property type="nucleotide sequence ID" value="XM_066814195.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047255"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="70" mass="8109" checksum="AADE34BABBB049A7" modified="2025-10-08" version="1">MHAPLHDLPLSFSYYLGEPPYPQNIVPERAPGSRRTSSLGSEKSFRYLKLGPVHWGEHTDEHKEDFHHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWJ6</accession>
    <name>A0ABR1VWJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar amino acid transporter YPQ3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009339</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665616.1">
        <property type="nucleotide sequence ID" value="XM_066813654.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046714"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="125"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8074676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="33795" checksum="7273741535EDD76B" modified="2025-10-08" version="1">MAVVHGISVHEAMSGVFGSISLTAWICLLLPQLLTNYRAQSAEGLSMPFLLIWLFGDIANLCGALVTGIAPTATALAAYFCFSDLVLISQCLYYNTLNARRARQRTASNATDASEDEPLLRRRRASSGAALPGSQRRNSMRHEESGFDPIRRVVTGEDETPDSNPALHNALSVAAVYIVGTLGWFISYKAGAWDAPESPDLPAAKSAVAIVGMSLGYLSAICYLCARIPQIIKNYREKSCEGLALLFFLLSLTGNLTYGASVFSYSQTADDIIKAVPWLLGSLGTMVEDCIIFYQFSIYSPKREPPKTNGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWK5</accession>
    <name>A0ABR1VWK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666172.1">
        <property type="nucleotide sequence ID" value="XM_066814210.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047270"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="30"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="302"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="376" mass="40711" checksum="5C5B29F1B70122AF" modified="2025-10-08" version="1">MAIPVYTREQGGVVAVAVVCTLVPLLVIGLRFWARQVVHRRFDASDTWILVAHVMKVVFEGGLGLPEDIVEATYGRDAGIAHAKAGYASLIGGVSAAYLCKTSILSLYRRVFTLPGERLPFYAVGALTLLCGLSTLVGYFAVVPIAKQLVPRPHFTDAEKMRNDGFQLYTGIATCFTDVMILCFPLGKLYRLRMDRRRKIGLMATFMVGFITCIVAIIRTVATYVNLSNSATVQTLFRGLEPTVGIIAACLPLLHPLLRCSSRDEGVDRFTQKPPRRGQQQQQQPGAGIRKTVKVTVTLSRNGGQTTLGGWRSSNSSQEPLGAGGGGASGVARGDGVGGLWWSSAGGERAVAGWESCFYCDMIMYTIGRLKKRLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWM5</accession>
    <name>A0ABR1VWM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665646.1">
        <property type="nucleotide sequence ID" value="XM_066813684.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046744"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="270" mass="25597" checksum="BDD6D4D277E44657" modified="2025-10-08" version="1">MKQTITVGAAPTEAAGKNGTNAAGGGVKTVIQTITNGAAKASQPAAAATVTVTVTAAADAKTVTQMMTVTQVQTITMVQMIAGGVSLGNPVPATQASAIASSAAEAASSANKQPPPAASTPATSVPVVAPSSASSVSTASSVAQTSSTKAAQTTPTSTSTPPPPPPTTTAAKPPTTAQPAQAASSLVLPVAGGGAVAAPAVSTMDPAGLQGVNNMPINLDGLTLNSNLNLGAIAAKKTPAAQGVQGLAAAAAPAATTTAASEPYKLVLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZC3</accession>
    <name>A0ABR1VZC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666455.1">
        <property type="nucleotide sequence ID" value="XM_066814493.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047553"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="31938" checksum="9AEDC38150E2B794" modified="2025-10-08" version="1">MVSYIAPVAHQLGLEKEKTERLESEIKRLNGELIKTRLENDALRKQLGMTPKPSRLHLRPTAASANRTRSAALVATPKPPPATLCKGNSGKTYIFNDANLVDVTHMIGADLRADWGSMYSFHQATVSSSRKTRSKVIKANPRSSTPIETESAFEPDELESTTFTESDDEEDTTTLLDDVSETTDSVEPTLALEKITRLHEVWQNKALSFVKIPSDIGWDLMTEAHHVIAKGAFYDYSKKHVPELQRKKFPGGKQEVLLEYHRIDEYISHIPMPPLENHFNTTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8P9</accession>
    <name>A0ABR1W8P9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ABC transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_007674</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667331.1">
        <property type="nucleotide sequence ID" value="XM_066811989.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045049"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="483"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="858"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="906"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="982"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1008"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1084"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="254"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="586"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="871"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="525"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="815"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="815"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="838"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8079856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1355" mass="148146" checksum="E33B38C5AA59578F" modified="2025-10-08" version="1">MNATANCALTNDGWSGPTVQGCRDDFDFTLSFEQYIFTILPASALLIVAPLRIFHLRKLPVVVGGSILRHLKLAGLLSFAALQLAYCIVWATWSPTSSAIRSPAIAAAGISFIATLFACVLSYSEHARSVKPSSTLNTYLLISIILDVATLRTLWRSQLPVAIQAVATASFGLKASILVLEATEKRGYILDKTYARSPEETSGIYTQGLFLWLNSLLGNGFRQLLKPTDLFPVEEGMSAAVLDGKFWKNWHRSFTICQPLLLSRFLSHLQNTSEPANIGYGLVAAYGFVYIGMAVSSAFYYNRASRMATMIRGMLVSAVYRKTIETSVTATGESASVTLMSTDVEAIARAARFIHDIWADIVQVAIATWLLSRQIGPAAVAPIILRGAMGAWVEKVQRRVGITSKMLGHMKGIKMSGLTKSLADSINQMRTDEFKAAAPFRLISSLSATIGQIPILLAPVATFAFFAIIALRTGQTFEATRVFSSLSFVILLAAPLFGTLEAIFDTFSALACFERIQKYLNKQPRRDGRRMDLSSPAPGQSQGLLSSGRVPSGHEPRSAHNDGLELATMQTRPATLPLDATEHYDVQLRNSSFGWADDGRFAINNVSFVAKKNQLVLLAGPVASGKSTLLKGLLGEVPFTSGTVTLSSHKLSWCDQTPWLTNGTIRKNITGFSPYNAELYDQVVYACDLQKDFAQLPDGDDFMVGSKGISLSGGQKQRVALARTVYSKPDIALFDDIFSGLDERTANSVCTRLFSIGEGLLRSWGTTVILATQSACYLPMADLIIMLGQDGSIEDMGTLPEVSTRPGFTKLFSPSDKHTVDEDTASKEYTTAKPPPKKFTEDAKPNDKRRQLGDHAAYGFYFSSLGVAFAAILLALEVATAFFQTFPSVWLKWWTDASAAEGNNGIGLYLGVYAALQVAGVISFFAITWFVLIKIIEKSGLEMHRRLLHAVVRAPLSLFTTEDTGSITTKFSQDLGQLDHNLPMGMLVSISSLLVCIAQAVLIVSATWYLAISFPVLIGVIYCLQKVFLRTSRQLRLMDLEEKAPIYTQFIETLAGLATIRAFSWEGASTELNHDLVDRSQKPFYLLLMVQQWLVLVLDLIVAALALLVVGLAVRLRDTVSIGFTGVSLVQLITFAETAKMLIQWWTSLETSIGAVSRIKQFTEDTQDENLPGENQPVPENWPVRGSIEIRGISASYGEGVRLNKALDDVTISVEAGEKVGIVGRTGSGKSSLLLTVVRMLDISAGSITVDGLDLTTLPREEVRSRLITITQDHFFLPGTVRRNIDPYESSTVAEIIVVLSKVGLWDAIQEKGGLDADFDEEMLSHGQRQLFFLARAILRKDCGRLVLLDEATSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA34</accession>
    <name>A0ABR1WA34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666846.1">
        <property type="nucleotide sequence ID" value="XM_066811504.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044564"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046225844" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="18849" checksum="C166FDC26D6B4215" modified="2025-10-08" version="1">MVSKTVALAAGLVSFVSASPIAPGAGKDLYWPVTEFFASKPHLSSYVRFKIAVPAPDSPVLTCSLSQETGFSGSTYLPYVWPGAAPCKDADGKTVEAMTWSFSQGMPEQATPDVSKDATFNVTYSETPNTSYRGSYTIPGAQVQIRLNEEPNPFDNDVTYVGPTEFRFTDIQVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAN0</accession>
    <name>A0ABR1WAN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mob1/phocein family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668035.1">
        <property type="nucleotide sequence ID" value="XM_066812693.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045753"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="541" mass="59525" checksum="0E75168F13C197D9" modified="2025-10-08" version="1">MSTLPPSSPRLPSPPPPAEIQLGPKSPGLGTTASRQAQEMEQTIADANAKRRIHPGTKAENMAAGPPLIPLSELESAFQLQEHLAALHYHHTASNTQPITRQTAEKLATPPPGIDRTLWLYELCRFLIAQCNSLIVGFLFDNPPCSQATCPEMRASEWQFLCAVHDQPKSCCAIDYCCHTLDWAANVVTNPKIFPSRFVVAAEGHDKGAVLKNLVNVFRRLHRIFAHAWFQHRGVFWTVEAQTGLYVFFKTVCDLYDLLPAENYKLPPEAEGLEPAQPEKEEGQPRVTAIARPPSREREENAPDDDQPLHARRSNTARHSSRPSLSTTVTTVIEEHEDENSDVANKLKNMHLSSRPEIVEEETEVEVPVIVEGEMMDRGPAETSSSPEQREPKEPTKAPAPEEGDAPTLGHEESLDTEANGESQDQESIEAEAGTESLPDSKDDSVEQPNDTSTRDFASSASPVEAEENVEQVEKDKKSKKSKKAKKAEKAEKAEKTEQGETDSTIQVTEVPDSSDPSPEEKSEEAPEDEKTASSSLSDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAR5</accession>
    <name>A0ABR1WAR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667612.1">
        <property type="nucleotide sequence ID" value="XM_066812270.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045330"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05362">
        <property type="entry name" value="THN_reductase-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="285" mass="30185" checksum="CFC8E5395E49A19C" modified="2025-10-08" version="1">MPGTTTVSAPAGTSKYDEIPGPLGLASASLEGKVALVTGAGRGIGREMAMELGRRGAKVIVNYANSQESAEEVCAAIKKAGSDARSIKANVSDVDQIVKMFAEAVTFWGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFHVNTRGQFFVAREAYKHLEVGGRVILMGSITGQAKGVPKHAVYSGSKGTIETFVRCMAVDFGDKKITVNCIAPGGIKTDMYHAVCREYIPGGSDLDNEGVDEYAATWSPLHRVGLPIDIARVVCFLASNDGGWVNGKVIGIDGHAMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBJ8</accession>
    <name>A0ABR1WBJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668350.1">
        <property type="nucleotide sequence ID" value="XM_066813008.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046068"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="187" mass="20650" checksum="A6CA1B3CC293AAC1" modified="2025-10-08" version="1">MALALGRTCQSAVALGVVKTRRGKTALRDCVAFLAPFQSCFGDSAWRMWSLRNPARRRIGILPTRRRCLELLGDQYALSGWMTCWACAATVAATSHSCLPPKKKPLLCFLVKTKVPSRFRDTIFSLVVSFVVGLVVPPISSPIFSLIIPPILYHIVHPSITPSLPDTAPDWWASPYSPELRYASLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBR9</accession>
    <name>A0ABR1WBR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate esterase family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668425.1">
        <property type="nucleotide sequence ID" value="XM_066813083.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046143"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF5">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="473"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="648"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1120"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1120"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1131"/>
            <end position="1147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1389" mass="150586" checksum="4C4F7164EC6EA792" modified="2025-10-08" version="1">MFKRLTQYLAVPNLNFDSVGVSNRTGPAEPRRALSSISARETGEPRRALTAIPARATGRVGSDADYPKNVEVPDVKVRQSNQIPFNFCPEDFRRPPKNCDNCGGDNYHHGICNDILLSGRQTYDCLRTGYGCSGYYCQCTHEGEDHNPQVTSTTVVDGQTGTVIYEPMTLTQYSNLRYHTTVTLTEVATTTTDGGTGLETALAVVFAGGIAWVAISEAGGAAAIAAIRPPGRKPEDAKEDDRSCKTNPEEECPNCGGSDGYGLCSSGDQAGCPCDEKQNCPNEPPRCSDQQCGGDNGESQCSASGEINGCTCCPDKAPLCTDNTCKGNSIQSCTGPKWEECGCLVYVDSGETLGGDEPDFGNQRPEYASSSVSSVAGYVFTAVWDANYTNLPGYPTLLPGVGTNILRYKETKPGEPVKKGTKLRILPVGDSITVGFLSDRNGGDGNGYRGQLKNDLSGDEVVFAGTESSGTMKNGNYVSPPFSDDKPQKKANSNRKAAWSGKTIQYISDHVDPSLKQRPNIILLAAGTNDMNPNHAISTEGNDPRGAADRLGKLIDKMVDACPDAVVVVAMIIDTCNQDQSPRTRQFQQLVPGVVRSRREDGKHVLAADFTTFQTSNLQDCIHPTNDGYKLMGDYWNSFVHQIPRSWIEQPVGPDPVGDDDGDGENGGIDKGIPPPDWGTSPVQVTSKQEVADAAEFARGGKDKPAKCNGPPNWRASGKIGLGLERNGDWQYHKDWVAKGEIASGLGWDEKYVRLHDMNGDGKADYVWIHPETGEIRCWLNNMPEPWSPAGTNNSIIGSGVLPAKFIYMADMNGDGMDDYLVVNPNNGAVRVWWNYGPDENWVNGWKFVEGGEIASGVPHANLQTLRFPDINGDGRADYVYIGEHGALKHHLNTGSPGGQDVLFHAMGGIATGAVEDISRLVFADMNGDGRDDYLIWDDDGGLTGFLNQPTNREGVPLTIRLADMDGDGKDDYVHVGDNGAISVWYNRGTTADHLTIDEIRFADIDGDGVDDWVLLDPESGAPTVYLNTGINDQDSLGWLWKPAENGKPIATGAAPASQVVFGDIDGDGMDDYLVLDPKTGALKAYLNTGPDPTPGATDTWPWKPIGTIATGLGPGHRVRIADIDGDGPHQRRPQVPRPPRRRRLGHRPVPEEIQFVDVNGDGKADYVWTSRLDGKARVWYNEYPSLPAWRDGGEIAGGVGTSGANVRYAKLQHTGRADYVALEPKTGAFAGWLGGCGDYDDAPKTHRVSIANGALGEAGKDYRRAWLVKEHPLGGEEPKDLCGFEGSQDNTNPSIVGPDYPVAIWEIPKLFGHECFYVGGLRRIGQLVCDGYHHKRHQNSKLMRTTNMANGLKYKKMRFPDDPLDYESWLQIDGDTCAGYWEEGFVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBU6</accession>
    <name>A0ABR1WBU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rRNA-processing protein FYV7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667957.1">
        <property type="nucleotide sequence ID" value="XM_066812615.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045675"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41805">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41805:SF1">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN FYV7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="23471" checksum="25AB82976154D06C" modified="2025-10-08" version="1">MVSKRPLEDDVAGAPEAKKPKKGFRVGPENLPDGPWRRKIDKVKKGLIEKAKLKKQYAKIKAAEEQTGGKPASGEQGADGDAEEDVPEAQIHPERQAMLDEDEPEAEPEPEAGAARQRRPRGPKQRRPDYFEKAKSEAERKKAAAEEREKEFQRRNEERQRRIEERDRFRKAMKKARAPGRDGQRRLGRESGLLLDKAKRMMGDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCA7</accession>
    <name>A0ABR1WCA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667626.1">
        <property type="nucleotide sequence ID" value="XM_066812284.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045344"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861">
        <property type="entry name" value="GLYCOPROTEIN 38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861:SF4">
        <property type="entry name" value="SH3 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G13610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="63230" checksum="1E825CF48743BE61" modified="2025-10-08" version="1">MGESKQGKVEGRSPSTKLVLASILAAVSPAMSQNGCVSLAGSKTCPAFSSASVSTGSYLIGLYPFLKDVTDTKSFDEQLNSYVRTSYVESKYQTLLGCGNINLLNTTNLYARFTTSVICNGIVQNSIQECSLTGNAARPLCADSCADFAQSEALVTSDKSLCSNPNGNSQNQIRADFTNCALPANSLSSSNCIQASDNEPQNCGYSDSTIGICSYCASGGINSTDTCCYNSKIDDRCAGVALPAITPVMTFPPMPTNTNGSTPAPESNQGHNGLSGGAIAGVVIGSVIGLALIALLLFLCIRRSRRRGDSQKGSVFNQPAPSRGGVTTAQSQPISEKRPTTAPQGYEILPGGRIARMSALEGHSGDSPSRHGGSRHGTSRHGLSSAGGATAAGAAAGYMASRRRGDNHSSSDEFADSPKSETRAGVLRPPPLTSRRNGSLSSGSILIGEDPQSPTSAGGMSGGVASQQSEQLPFFKDYYSQDDIHPGDRVAVLWAYQPRAVDEFALERGHMLKIVGIWDDGWATGVMVDEMADEWEARRQMQRDSGVSNTSGRMRETSPPVSGEIKAFPLVCVCLPEHWRKTIEGDGSTEAGSSAHPGSQWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCC0</accession>
    <name>A0ABR1WCC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007622</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667279.1">
        <property type="nucleotide sequence ID" value="XM_066811937.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044997"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1340.10">
        <property type="entry name" value="RNA polymerase, Rpb5, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.20">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00025">
        <property type="entry name" value="RNApol_Rpo5_RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014381">
        <property type="entry name" value="Arch_Rpo5/euc_Rpb5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005571">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036710">
        <property type="entry name" value="RNA_pol_Rpb5_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000783">
        <property type="entry name" value="RNA_pol_subH/Rpb5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035913">
        <property type="entry name" value="RPB5-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007129">
        <property type="entry name" value="PRK09570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01191">
        <property type="entry name" value="RNA_pol_Rpb5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03871">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000747">
        <property type="entry name" value="RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53036">
        <property type="entry name" value="Eukaryotic RPB5 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55287">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb5 N-terminal" evidence="7">
        <location>
            <begin position="13"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase subunit H/Rpb5 C-terminal" evidence="6">
        <location>
            <begin position="162"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="235" mass="27087" checksum="FE2A693ABFDB9323" modified="2025-10-08" version="1">MADQEDANREANERSIVRTWRAWRTVHEMAADRGYELTQEEVNLPLERFRDRYISNEGTVNRSLLKFSARPSDDMMRKFQKPATPNDPSPGSDCGTIWIEFLDESTLGAEQMRKFGKFCAEHNYAAGVLVSNVAVSASAKKEIAKFAQWTAIEWFLEDDLLINITHHDLVPRHVILSREEKAALLKRYRLKETQLPRILVRDPVAKYLGMKRGQVVKIIRKSETAGRYASYRLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDK6</accession>
    <name>A0ABR1WDK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">diphthine methyl ester synthase</fullName>
            <ecNumber evidence="4">2.1.1.314</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_008072</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="EC" id="2.1.1.314"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the diphthine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.314" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667729.1">
        <property type="nucleotide sequence ID" value="XM_066812387.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045447"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01084">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882:SF0">
        <property type="entry name" value="DIPHTHINE METHYL ESTER SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="DIPHTHINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036432">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="288"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8080254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="316" mass="34998" checksum="BC17D135412A3497" modified="2025-10-08" version="1">MLYLVGLGLSDETDITVKGLEIVKKASRVYLEAYTSILLVDQSILESYYGRSIIVADRETVEFDSNDPSESNELLRYAATEDVALLVVGDPFGATTHADLVLRARHLGIPVSTVPNASIMSGIGACGLQLYNFGQTVSMVFFTDNWRPASFYDRVRENRQIGLHTLLLLDIKVKEQTIENMMRGNKVFEPPRYMTVGQCARQMLEIEEEKGEGVYGPDSLAIGAARVGGRNEKFVAGTLKELCDSDDALGPPLHSMVLLGRRAHELERDFARGFAVDKETWDTLWARDYGKQDAPAAPQTDDNAEEKEDAKVQASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDQ4</accession>
    <name>A0ABR1WDQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional activator of proteases prtT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008449</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668106.1">
        <property type="nucleotide sequence ID" value="XM_066812764.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045824"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF17">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="6">
        <location>
            <begin position="214"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="559" mass="62372" checksum="A643B3C188B6D001" modified="2025-10-08" version="1">MAVCYKELPGQPSRWKQSMETKIHKLQLTVGRLAKNIVSPEEAEQMLTDEAHDTPMDQDFAATQAAKSTHPGPSGHWGVVMDLDSGPGAIPGFYIAGNQPPMQADPHEDFILRGVVTLHSARGCFDTYKDRLDHFPYRILNDQTAGDFESVRSASALLTASVCAVGALHSASSEFEAYYREFVRLSAQQIHSRHHTTDDVRALCIGAFWLSDLSWSLIGAAVRIATELQLHKSFSKALQGDRQHYLRARLYYLVYACDHRFSVAYGRPPMTRECEAVRNARDFLRCEFATEDDGRLVSQVLRWSICSNIFDTFGVDVDRPLSEFDLPHLRRFSIALDSIRAEWIDRFIPNAHVGNYPRKGVGLQYNFAKLYLCSHAFRGVSTDDFASHSPEVIMALEEVANSAVLAASAILRAVIADPEIQGFLDGLPTYFDTMIAFAAVLLKVSTKYSSMVQVYLQELRRLLRTLLATLKKVTSSMHQRHLLVSITAGLESLLFRCGVIGSTCAAEEQEVTAVTTGTDAGIDQLGYNSATSFSMEEYDFLFNSDVDFSLEFLDQENLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEY6</accession>
    <name>A0ABR1WEY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668133.1">
        <property type="nucleotide sequence ID" value="XM_066812791.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045851"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="469" mass="51527" checksum="A85652A1A08844D0" modified="2025-10-08" version="1">MPLRQLQRPLLRTTIAAAAASTSWRPISVQLLHGSSCRRYSSSTTSSSTDASSQQQTTQPKKTLFEELFPDESKTGPSSLRRALNGSSKTHKDEDVEPEPLALPKEFQAYANDPDADVRAAYDNRALLVLSGAPKSLTESDFFRTQLGGPARHVEGWSSAGIHRIVPMRDPETLEPAGQYYIVFESGTAAVAWQEEVSTLWRLARARNWSRQLVTGDGGGSFESRQLQRLLADRGKTAKKKNKDQKHALGKTDKHHSLAGYESLTHDEGEDGNDLESASVRNFTLVPQSQRYDIERPVYTRLDSLLHNGAPSLVERLMDKAGTRHLVLLVLEGGRLSIPTLRALVHEDGAERNLAWRVKGLDRDYNDSQRGGGGIMAFGKSSLKASEQAGPEESLLRQINGAMGEEGEQKEEQHQQQQRGWLRRRSRGRLGNDKSSPTRTGDGTGSSCRSSTRPRRAASSDTGTGGSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL85</accession>
    <name>A0ABR1WL85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_005523</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668761.1">
        <property type="nucleotide sequence ID" value="XM_066809838.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042898"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023230">
        <property type="entry name" value="Glyco_hydro_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF2">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="LacZ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00719">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta galactosidase small chain/" evidence="9">
        <location>
            <begin position="809"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="35"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8084252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1091" mass="123377" checksum="9C67EB2D1551BBB7" modified="2025-10-08" version="1">MAPRTIQTPTRAPPREVDPLINSIDSLHLDLTYTYSPIGSPSSSDERGASSPPSPEEQCSSKLGSQTNGHNKPKVRPDHVPDWSNLQVIHRNTLPPRSHFFTYDSERDALSADVTRARSFLLSGTWGFHLTHGPFNGPTDFWEPSFDNSKWDLVKVPGMWQCQGFGKGPQYTNVNYPFPVDPPHVPYDDNECGRYVTRFQVPDRLKKDGEQWRLRFEGVDAAFTVWLNGVEIGYSQGSRNPSEFDVTQALDPDSDENYLAVEVYQRCDGSYIEDQDQWWLSGIFRDVWLHSFPSTRFEDFHIQTLLDDDFQDASLSVDYKLSGGAKDASVTFKLLDAEGSVVLEETQVASNPSSCSFKRSIKSPHKWTAETPYLYTLVLSAKDVHVSHKVGFRKAELIDGVFCVNGYPVKFRGVNRHEHHPVSGRAVPFEFLRRDLYLMKFHNINAIRTSHYPNDPRLYELADELGFWVLDEADLECHGFGEVGEDPASFTSDNPGWEEAYVDRARQMVMRDRNHPCIIMWSLGNEAFYGRNHQAMYDEIKTLDSTRLIHYEQDYDAKTADIYSRMYTSVDDMIKFGEEEGWKKPFVMCEYAHAMGNGPGAIKEYIDAFYKYPRLMGGFVWEWANHGLLTKNAEGEDYMAYGGDFGDEPNDYNFVMDGLCFANHTATPGLIEYSKAIEPVQVVGNDGMVVKIINRYDFVSLDHLRCDWEIISDRSQIIGREVYIPKGIKPHTTAKLVIGGFPQTTTFASETWLRLQFSRREATKWAYRGQVVAFGEVLLTPPRPLALLKTVSKAPGPRLQEVDGMIQATLANGTTFGISTATGSLCSLTRADTVPKSNLMTEPMVLDFYRALTDNDRGGPFGKEWIERRVHQTKNHFRRITTVEGEADGVCKVIVEGRVAPPALAWGVDTVTTYTISRDWCSVRVQAAKPSGPLLPATFARFGLSFAMRGCASWSGSAGARGVRAQHMNTWGLATDALWTDYEFPQEGGNRTDVRWVEFRDRWGGAEDKGRLLRARFGEHDGASFSASHYATKDVDECTHPFELRKRKREDTVVRLDWFHHGLGTGSCGPATRPEYQLRTDRGFDVEVLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLD1</accession>
    <name>A0ABR1WLD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005572</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668810.1">
        <property type="nucleotide sequence ID" value="XM_066809887.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042947"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF52">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="685" mass="76955" checksum="8E3A56838410D135" modified="2025-10-08" version="1">MARRFPSQRSTPIINLDEDIRVTPVIDLSEDNDEEVRREVGLVIDLTGDDDEPQVQRRPFSHVPPIEIPPQGVSLIQHNGFHIRLGSHVEVMAIPASCQAQFLKVTAIVDLPDGVFVHGLPFARTRHVNNQLPKKLNEVCLILDSARDDPRTEEQQATVAVPLHHVIKTRDLECTNADYPVFKYQLRRNDVLHTEENGRLVCRWKRKRVWASSQARRTGKPPKEFAIIHIGPEDVAKDAYRVSEMERFNDWTAGKTRHAPNPGDVPIQNHAWNFQPSGRHQKYSFGDIFCGAGGASTGARGAGLDVLMACDKDRTASRTYKSNFPTTEVFNEDVYDLITKKLYRGPRLDAIHLSPPCQPYSPAHTIPGQHDETNQAALFACHEIIKRKCRRVFTLEETYGIMSCANHQGFFDALVHGFTNLGCSVRWKIVELRNWGVPMKRLRLIMIGSCPGEPLPDFPANTHSQHGGHLPPWATVARALSRMPNAARHNDKSHIVTPGMRFLFPLPAWDANKALPRTIVTGGTPGDKPGDYHPSGTRKFTCRELATIASFPVDYNFEGTITEQRRQIGNVFPPIAAQVLHTHLRQCMERTDRARRAMNPLPQPRNPSPYEAMVIDDSDDGNDVIVVNDDDDEDVVILDNMYDRPSSAASSRTLGRLELELDDDSPDGNQHAMVLDVDQQIIVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM03</accession>
    <name>A0ABR1WM03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SFH1 subunit of the RSC complex</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005729</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668967.1">
        <property type="nucleotide sequence ID" value="XM_066810044.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043104"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="55"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="466"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="492"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="571" mass="62134" checksum="34A5A18B02D08137" modified="2025-10-08" version="1">MGTRSAPQAFLSSYAPRLRTYNNSLLTPVAHPTQAVGPQSRTTKRGTTVINYAEDGYDYDDDETDGDRRRPTGLRSLRREDSTSRLDASDKVGKDTIAPVDLQGIWRNWMLKSRTRSDLNAQAQAAMPVTLIPIRIDVDIPAFMPAAPFPPTPGPGEMTVPYKLRDIFLWNLHETVITTDQFAMALVQDLDLPNQVPIANEISKQIRTQLEEYAGVALHPLFHSEDATAVANGNVAAAAAALRSVHDTPAMPGTPLQQSSSSFVGGSNTPMLSAVDTPSKGPTASALQVTATASPIAADADDYSPDDTYRCIVSLSLNLSSSVYSDKFEWSLLHPPGTAEAFAKITCTDLGLAGEWVPALTHAIYEAVLRLKKEACESGGLVAGWGAMGAELPNDAAHGADAGWRYDPEHLAEDWEPKIEFLSKEEIEKREGDREREVRRLRRETARFSSNTGMLGGMPLGTVEVEEERMGRGERSKKKRRFRSLSPLGRSGTPGRGTPDVGGYGGGGSLSDQERFNWRCLHCRVWGTSVWAVRKGPFGDRRMGANETAAQVVAKLARNGPASYLIVLSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN74</accession>
    <name>A0ABR1WN74_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669468.1">
        <property type="nucleotide sequence ID" value="XM_066810545.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043605"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046812302" evidence="2">
        <location>
            <begin position="21"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="182" mass="20303" checksum="8F716A3D867CBE18" modified="2025-10-08" version="1">MQLLPALLFLGAYTLPLISAAPVDGRCTDFRAFAPSLSDLSYMSRHALPRKITTATHSTIKHLEPGFHEFVYQSAKAIDSGESYSRIATRHAGACAVGSAVGLVLLWILARCLAAKWRKYRSQKEWGRKSRGSFIQRSRPLSIGSRGEIVFNTDEKEWDVRWARESGAADKACDRTQGVRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN96</accession>
    <name>A0ABR1WN96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_006285</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669523.1">
        <property type="nucleotide sequence ID" value="XM_066810600.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043660"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17982">
        <property type="entry name" value="DEXHc_DHX37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF99">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="377"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="576"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="109"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="247"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8085014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1180" mass="131575" checksum="9DDE58D781410A1E" modified="2025-10-08" version="1">MPVKKFVPRQRKHKVLARQKASTEAQPEDSNQLESTKDSRQELDDRKEQLRKELQGEGPKISGKKAKRLEKYIETKIRKDENRALLAKLAENKIDTSLFSSSRTLGQKTETKKQLLQRALREHAAGIADHGDELFEERPTAPESNEETLPQKHTPAASSQDEAQLSKPQASEATPVQPAAGSGLKRPLDVDDEGRPVIKKRQKRGGVKAKASLAAPKVAHPEPVHQEESDSDSESEDDEWKGFSSENEPDDQGSGMEEDSSSENEETGSSDDEDEDDSDEDGEPDTKQRSSAFKAWAHQQRNEAMGYTPVESNAMLLDIPRPANFEPRPLEQEPLPLELQPTTNVARKAFAVPVTRQAEIQEARLKLPVVAEEQKIMEAIHNNNVVVICGATGSGKTTQVPQFLFEAGYGSPDSPTPGLIGVTQPRKVAAVSMSKRVSQELGNHSHKVAYQIRFEGTADDNTAVKFMTDGVLLREVSNDISLKKYSAVIIDEAHERSVNTDILIGMLSRVVKLREEMAVEDKNIMPLKLIIMSATLRIDDLTKNPVLFPSPPPVLDVEGRQFPVTTHFARQTRHDYVEEAYKKILRGHRKLPPGGFLVFLTGHDEISRLSKLLKSSSTGLNSAAYPKVRISANDAPLEVEDIEFGNTNDTTQDDYDEVEIVDDVDDEENEEDDTEFDIPDQQGGTGPLKMHILPLYSLLPTKEQMKVFDPPPEGSRQIILATNVAETSLTIPGIQYVFDCGRSKERRFDKDNGVQSYEISWVSKASANQRAGRAGRTGPGHCYRLFSSAVYERDFREFADPELLRMPIEGVVLQLKAMRLQHVVNFPFPTPPERQSLAKAEKLLKYLSAVTPEGQATDIGATMARFPLPPRFARILLVGHLHDCMPYTIALVSGLSVADIFIPETQAIPALAEREEGAYRTNDDVIAETEQQQIRKRYNEVHRNFRSLDDTSDAIKLLQAVGEFAHDPTEKWCEDHFARFKGLSESQKLRRQITNLLQKDIPAFANLTFQEKLDRPSAKQIAALKQMVAAGFIDQRRPGRAIDVPYIPLHPLDTQDDADKLVYIHPSSSLAHRSTQELPEYIVYSHLQRQAPSVDATKRPKTRMLALTNVTGAQLAALAKGTPLITYGKPIKEIKTNDPSVREIWAVPYLRAEGTGGQGWPLPVKKITQRKVPGKGWVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNR6</accession>
    <name>A0ABR1WNR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_006451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Putative oxidoreductase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669689.1">
        <property type="nucleotide sequence ID" value="XM_066810766.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043826"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196:SF1">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8085180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="33189" checksum="E91BBF21FC3CC894" modified="2025-10-08" version="1">MPASSPSPLVTGAIAAAAVPAALYLANRLAGSKSSKRAGLAPTEERVCIIGASSGLGRDLAKKYAARGAKVCLVARRAELIAALAKECGEEDRCIGIAADAAVAEDMVRVRERILQAWGGLDTLHICAGVSALQPVMDLTGAAPGEDVSAAGIQKVVEITGRATQGNLVGPLVAALTFIPMLQRTSSFPAILLVSSLAAMVGAPTRALYGSTKASSLLLFQSLAVEHPRIAFTFLLPGTIEGNFRASAVDAGPVREADPNKTGLKIDYVANRCIAAVDAQTTGNIFLPFFPNFLAPLVYTLWPATVEKAARKKYNFEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ41</accession>
    <name>A0ABR1WQ41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Golgi apparatus membrane protein TVP23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006904</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Golgi membrane protein involved in vesicular trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Golgi apparatus membrane</location>
            <topology evidence="2 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TVP23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670142.1">
        <property type="nucleotide sequence ID" value="XM_066811219.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044279"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008564">
        <property type="entry name" value="TVP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019:SF7">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05832">
        <property type="entry name" value="DUF846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="194" mass="21672" checksum="E89DF657ADF7E764" modified="2025-10-08" version="1">MEQQPQQQNAPGSLSWRLSSHPITLLCFLAFRISSLLVYLFGMLFTENLVMIFIITILLLAADFYYLKNIAGRRLVGLRWWNEVDPQSGDSHWVFESSDPATKTINATDSRFFWLAMYAQPVLWIALAILALVRLKFIWLPLVAIALVLTVTNTLAFSRCDKFSQASNMAGSALYGGSLAGSIASNMAGRLFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQB7</accession>
    <name>A0ABR1WQB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668783.1">
        <property type="nucleotide sequence ID" value="XM_066809860.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042920"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="9"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="33133" checksum="EAE90E1F8F8688EA" modified="2025-10-08" version="1">MASPSAPQLIYGCGGLGHEIPADSAAELLQTLKDGGVTRLDTAALYPPTDIGASQRILGKTRASAELGFTIDTKVMVSISGIAGTLEPAKIEKSAAQSVKDLGFSDGGAKINVFYAHAPDVATPLEDQAAAFDAQYKKGLFNKLGLCNFPAPMLEEYMAICERSGYIKPSVYQGLYNLIDRRHEGAVMDLVRQHNMTFVAHSPHAGGFLHGGLTSGRGNIMSMDARRYDTAKHHAAVRALDKALEPHQGLAKTDVAIRWLAFHSRLGPDDAIIFGASKIAQAEQTIAAVAQGPLPDGIVAALDDMWKALIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRC1</accession>
    <name>A0ABR1WRC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_006252</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669490.1">
        <property type="nucleotide sequence ID" value="XM_066810567.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043627"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="805"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="996"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1035"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1066"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1102"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1138"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1179"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="436"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1250"/>
            <end position="1478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8084981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1671" mass="181695" checksum="0B79FADAFE46C6B0" modified="2025-10-08" version="1">MAFLSQTWTLTSKNLKIVFVRHSFATITRAFILPILLAAFLSFARNLFVPPAVYGIQDAHGVRSLPDALDYASGTDRGIVVLVNNGHAGGDIDRVIDKVADVVTGAGKNATRLSDPADIGFICKSSLRAVTGCYGAVVFESSPTEGKRNIWNYTLRADESSRFSNWGLNGRPLPAETREYAFTSMTQEERSEQVRQLYQQALVNFLAVAFIATIIGVCYHMTGFMATEREIGMSQLLDAMMPTKRLWEAQVARLLSHHIAFTVVYLPGWIIAAIIIGRGVFASSNVGLLIVHFLLSGLALASLSIFGSAFFKRSQLSGVVSTIAYILLAILAQALTAPNTAAVIVLSLLFTPCNFVWFLTYVARYQKHSWPTDLVHTPPDSPWELPGIVFWIFLVIQIFGYPILGAYLERVFHGSTTKGRTILRGQDAANAPQAAVRLEKFTKIYKPSALRRLFSFISPAPEPVVAVNELTLSAGRGQILALLGANGSGKSTTLDSIAGISKLSSGNITIDGTGGLGIAPQKNVLWDELTVFEHIQIFNRLKAPGNKSSKAEIKELVHSVDLALKINAQSKTLSGGQKRKLQLGMMLTGGSAVCCVDEVSSGIDPLSRRKVWDILLAERGKRTIIMTTHFLDEADLLADQLAILSRGTLRAQGSSVELKDRLGAGYRIHVFNAQDIKNPPEVEGVTRKIGFDVISYIAQSSAAAAEVIRTLEAVGISDYKYSGPTIEDVFLQVAEEVHGEDFSKLQASAEGITDDKQVSSENVQVVEGPEKEKDSLALLSGKPIGFGRQLTVLFKKRITILKTNWFPYFAAFFIPIVAAGLVMLFIKGQSQIGCTPSDQSSSSSDDNTFQDLYNNITLAVGPASRVSRQDLTRLFAPILFPDGFAGLLAAVASGSGSDGNGSTPDSFFDKLNVVNSLGEFNDNIEQHRKNVTPGGYWLGDSNSPPTLAYKAEFVDLYSSVATQNLQNIMLVNTTIATTFKPFDSPFSPGMGNSLQVLVYMCLALSAFPAFFGLYPNIERRHNVRGLQYSNGVRSLPLWVAYLAFDFAILLVSTAFVIIIFATLSNVWYHVAYLFLIFMLYGLASTLFAYVISLFCKTQLSAYAFAAAGQVVGFLIYLIAYLCVITYAPANKIDEDINLAHFIISAFIPIGSIVRTLFIALNLFSAACDGFQLAPNPAAITVYGGPILYLIIQSFVLFGILIWYDSGAGMSIFHKFTRKPIEVKPDESMSDEEVANELTRVTTSSRETDGLQVVHLTKTFKKNTAVDNVTFGVQHSEVFALLGPNGAGKSTTISLIRGDIQPSRNGGDIFVENVSVSKKRAAARANLGVCPQFDAIDSMTVLEHLRFYANIRGIPDVEHNVRNVLRAVGLEAFSTRQAHALSGGNKRKLSLGIALMGNPSVVLLDEPSSGLDAAAKRIMWKTLASIVPGRSILLTTHSMEEADALANRAGILAKRMLAMGPVENLRQRFGDALYVHLAWVKRTFPGADVEEKTYHGQLRFSVPASAVLADKDHGQRSAVGQLIIMLEEQKESLGIEHYSVSPTTLDQVFLTIAHQRGDLSVGPPWHQVYQALTRILSKYRSLYDRWPTQSCYPQSVAAITAEVKVVARFLGPRAQVHARRRVKAATAAITAAISSPTSGELINMCADAVAHCIGPQAGAQLDGDGAEGLSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWS4</accession>
    <name>A0ABR1WWS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GeneID" id="92039921"/>
    <dbReference type="Proteomes" id="UP001433268">
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="116" mass="13166" checksum="C6A5DB0F1ECA7EF7" modified="2025-10-08" version="1">MVGRWNWVTAAFTVPVLLRSPSFHAGVRRVHRVLDQRQNGPHPDEPLRPGEATEEQGVQRGGFMKYFFEEMGNQALGRPTPDDHDLGGNSLEDKATSTKKSKRQEERQPTGKWKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX19</accession>
    <name>A0ABR1WX19_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002674</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
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        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670607.1">
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    </dbReference>
    <dbReference type="GeneID" id="92040049"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="149" mass="16558" checksum="582CCCC11F9042CF" modified="2025-10-08" version="1">MAHLDLSRKRKLHANAQQSVSIRHQATALPVGLLPTARILTFGYDANVADWKGMVSQTRIANHAGKLLSSLAAYWDDDDTLGRLWRLRNSNPGHTPKNTLRSTHGIAFLRTPHRGASLAEWAELLASHLVMAKQTNGMIADVRKQESEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXB4</accession>
    <name>A0ABR1WXB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670696.1">
        <property type="nucleotide sequence ID" value="XM_066807078.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040138"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587:SF4">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="131" mass="14916" checksum="EEBAAAF2BBFEF7E7" modified="2025-10-08" version="1">MSSSEAEQKKAPQVATASDESEQDQGVESQQEQEKQVAAPRKRRGRRQPRRRAPVQEESEEDDDDDDNQMQQFQQQQMMQQQQQQQQMQQQQQGGGGGGKSDTLKLRLDLNLEVEVTLKARIHGDLTLALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY69</accession>
    <name>A0ABR1WY69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-type lectin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002998</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670931.1">
        <property type="nucleotide sequence ID" value="XM_066807313.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040373"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07308">
        <property type="entry name" value="lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF45">
        <property type="entry name" value="RE50040P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286933" description="L-type lectin-like domain-containing protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="9">
        <location>
            <begin position="31"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8088037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="35951" checksum="78662EEF73A117FB" modified="2025-10-08" version="1">MRWQTWLSSALGLAATARAAVSHDDEGNIRSISLRTHTLVQPYLDSDMASRWYEFGGDTIIRTDSYVRLVSDRPSQNGWLFSRVPLTATNWEIEVEFKIHGQHQLYGDGFAMWLTKERGKMGSVFGHADNFEGLGLFVDTYKNNRPGVVFPYVMAMYGDGKTSYNKDNDGKDQEFAGCSARGIRHASVPTKLKLTYFQDKQLKLELQYKSEDEWTLCFETSEPPGHPLGHLSRLQCRDWQLSDNHDIISVNARNLYTSGGQTGSKSSPGGRKSKQHKPEKQGGGWGWFLFKIVMVGVVLGGGYVGYTVYRTKNRSHRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYM3</accession>
    <name>A0ABR1WYM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Prenylated Rab acceptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003226</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671159.1">
        <property type="nucleotide sequence ID" value="XM_066807541.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040601"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004895">
        <property type="entry name" value="Prenylated_rab_accept_PRA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317:SF0">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03208">
        <property type="entry name" value="PRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="324"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="398"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="472"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="510"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="539" mass="58503" checksum="3B266A5E7627C6E8" modified="2025-10-08" version="1">MASRIQIPLDVLTSRLNISDRFAGFRNTSLSSRFSNLRPVGEFCDFKRLSKPENFSEMQSRVNYNLGHFSSNYAACFFILSIYALVTSPLLLFDIVLLFAGLWLLGKMNGEDLVIGTFRATSSQCYTALLVTVAILGLIAPTFSTLLWLLGASGVVIIGHAAFMDKPIDEAFFRGGGLGGRPQAPKYAPQWGRPSRRGRGREAPQKGDQGFWSQSERVHELDSDDSDTQGAGLTSGNRRFISDPLHFTGTELGRGGKSRGGYAYQASDDDEEDDSTEVESEEDEEEAELVEYALAKIRKAQAKGKQDVKLNKEELAALERRRKRLEAEAEQGAKRKQKPERIAVPLSQFDPSAMEAPRKRSGVSASSEDSTAVVSARSRSGPPVGLFPPPNASRSSHRSSTSSSQQLVSRSSSGRNTPDPFKYQTAGSRAASGHSVAGPRRNMSGSSDPSRRSVHGSSRSIHRAQSSEESGESTTSDETGNGVHISRNRTPPEEIVVVEGSPEPEPGPRTRSKASSKQSPVKRKSASGTSTSGRKRKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ42</accession>
    <name>A0ABR1WZ42_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein SYS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003382</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671315.1">
        <property type="nucleotide sequence ID" value="XM_066807697.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040757"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019185">
        <property type="entry name" value="Integral_membrane_SYS1-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09801">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="215" mass="22994" checksum="676C6CBFF9347992" modified="2025-10-08" version="1">MPRRRKPPRAGAIGELPPLRILSQIAAIQGIYYATALILFLFTGLVAGTGFHMDLVFGWASLRGDTTQGFVYAFVWLCCSAVGGGISRARGALETRPRLCVYDALPAPLRCHLLHRLPAAQLHVVGDEPVLHRRHDRDGHVGCQWRELRPINFGGNGGRTTGAAGTEGNGHAGGNPDGGGMGDEEMGFGRGRGRGRGRDGAGEYELASIREQEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ85</accession>
    <name>A0ABR1WZ85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671335.1">
        <property type="nucleotide sequence ID" value="XM_066807717.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040777"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="162" mass="17789" checksum="9C61E0A60C87C2D3" modified="2025-10-08" version="1">MGYPQTLVNIIADIAELVEDSTHIALRRGLLRSSQSEGYLAAPLVYSSSCEELEASLKRWSMPPMPHGLSPVATMLLRSAWETFRMAAFLYLWRCFGFRANVLEPIRADRVALANTYVTAIISNCQAILQLGSIPRISIGNALLWPLVVVGCECGTGSTEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZA1</accession>
    <name>A0ABR1WZA1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">General amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003403</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671336.1">
        <property type="nucleotide sequence ID" value="XM_066807718.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040778"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="89"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="199"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="519" mass="56813" checksum="C4565E31E9DBB515" modified="2025-10-08" version="1">MHFAEQLRLRRAWKEVVAGRRAQQGQTVRTWAERTLGTAVPRLPDGSVTNVVDWPRMSGQLSARQLEITESMPSQLLGKMATGTWTAQEVLLSFIARTILAHHLTNPLTDPMFDRGLRRAADLDDFLREKGHPVGPLHGLPISLKDAMNVEGMPTTLGFVARADAKPPHSDELVSRLSAAGAVFYCKTNVPQSLMSGEGSSGGEGSLVALGGSPLGIGTDIAGSIRTPANFNGTFGLCPTYGRFPCHDAEQSSAGYMLNGVAGPLSRSIDGLEVYTKSLLSLKSREWDPTCERLPWNEATYQDTLRSGLSGGDGLCIGFVANDGVTTPHPPIQRGMREAREALQRFGVRVVDVQLFDGTEDMWKMMTKMFNSTGGSDFRDLVRQSGEPISEEIELAAPEDALSASKLFQLGRQILELRHRILRRRQDTLSITGTGRPVDLFVLPSGCTVAPPHGTMKYWLYEAISNLLDWTCATIPVGHVTSTKDPKPDMDDDFKPLSSFDRYNWDLLSSSLLVVQSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZF0</accession>
    <name>A0ABR1WZF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003513</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tannase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671446.1">
        <property type="nucleotide sequence ID" value="XM_066807828.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040888"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF2">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="531" mass="57912" checksum="A2FF84D87B8AC69F" modified="2025-10-08" version="1">MSATAFGRRDVPPACNDHSFMYVLPPNVSIEKVDFVESGNTYGEGLRNLNYPIQPTNLPDLCAVTIFVKSSSSSAYRFGLFLPVDWNNRTLAYGNGGFGGGINWLDMGAGVKYGFAVLSTDTGHNSTSGDISWALNNPETKTDWGWRAVHGSVEIGKKVVEEYYKKKIDYSYYSGCSTGGRQGLKEVQISPDSFDGVLVGSAAWYTSHLNTWVSKVGTYNLPLTAPNHINASVFPAMAKEVVRQCDRLDGVEDGIISAPDACTPDYTVMACNRPGVNQSACLTAAQIETAKKAYGDYRAADGTLLYPGLSPGCENQWSLVLSQNMTSLYGLNYARYFLYDDPDWQWQDYNDSAPEYAARKDPGNATADDYDLAPFRDRGGKMIMYHGLADGLVPAKGSDLYWDRVVRATGGGNATATQDFFRYFTVPGMGHCGGTAVDAPWNFAAPFQASTLGNDSWSVPGYRDARHDVLLALMGWVENGTVVEDVVATTWDTFSDASTPVLKQRPLCPYPATARWDGRGEVDAEGSWACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0L6</accession>
    <name>A0ABR1X0L6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_003907</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671840.1">
        <property type="nucleotide sequence ID" value="XM_066808222.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041282"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048682">
        <property type="entry name" value="COG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048684">
        <property type="entry name" value="COG4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013167">
        <property type="entry name" value="COG4_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048680">
        <property type="entry name" value="COG4_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20662">
        <property type="entry name" value="COG4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08318">
        <property type="entry name" value="COG4_m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20663">
        <property type="entry name" value="COG4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00762">
        <property type="entry name" value="Cog4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="COG4 transport protein middle alpha-helical bundle" evidence="11">
        <location>
            <begin position="201"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="107"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="610"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8088946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="761" mass="83691" checksum="CA41CC582C91D651" modified="2025-10-08" version="1">MSATNHLNGDSPSTTAHAAAAGAPTLRRLSIHHNSSSNPSIGDAHSPEDVRASLAALHTREASLTSRLQSLFASQADLARELSRLDLLRANLGSQVIATRSVSNGMLASAAETAGRLSNRVKELDLEKDRVQQTLQVVEQVAELKACVHGVVGSMGAPQDWEAAAGYISRASKVPESVIKGGFAAAIVPSVEVPDAPWVTLENAKESLCGLFLREFEKAAQEGDGAKVTRFFKLFPSSVTWKLVPGAAGQKDGFLYANALTKLFEHIAQIVEGHGGLVERHYGEGKMVKVIERLQMEVDVQGGIILDSWSDERTVERKLTDVKSYPFSFLVQSFLPPQKGITGTPRMNSPALGGGTNARDSEDEGVNMKEVDALLNEIALMLGRWSLYTRFLAGKCKLPGPDENAALSIPDALSKSNMLRKVSDKLVTPYDILSTFYFRRSVEKAFQLDESPSGLTLNINKPRDVVGHVIPTIGRVLGSDFIGMVQRRMRDESYPKPVIQGGFPPEDKIVSFIILINTLDVATEYLSRIITQCLGTSEEGTGPAQSSPIANSFPFEHDATFVTSALTTLNSSFSTKANELLSDGLQVLLNMVVKQRLRPINSDTFRDADYTLTEDELAEIAQQNDEHEEDLMDHVQRRFEHGWSGLMKPIERLMTPKTFSTLMMSTAKHLAVVLEKRIWSSSGRINAFGAIRMERDFSGIVRVVAKGNYSVREAFARVTQMLMVANMEDDEWDETMAEGEDDGIQWVLNEEERRKARNLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0U0</accession>
    <name>A0ABR1X0U0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671943.1">
        <property type="nucleotide sequence ID" value="XM_066808325.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041385"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="231" mass="26050" checksum="3E2147C04B1C626D" modified="2025-10-08" version="1">MAMDKTQHSSPMDTDFPSPSTAYSPAESQFSTSSLPSSMSSFDLDMDMDLDLEMDREAMPMSPVMAPSATSSSPASLAAQINHSTGIHAPIFEAAADLTSRRAAENTAFREKVRQMALPLAPLVQLTTGDVHPRFPATLLNFWLLTDHELESLASFYHQRTPCVWTRHYPCPVAWSPSMPLEEKRRKIGKFIGLRGCETPVSSKSEEQLMEEARQARWRDEDEMWRRKTPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X185</accession>
    <name>A0ABR1X185_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004106</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672039.1">
        <property type="nucleotide sequence ID" value="XM_066808421.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041481"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11309">
        <property type="entry name" value="14-3-3_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="3"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="233"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="233"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="267" mass="29706" checksum="2CDD5DD7F6953852" modified="2025-10-08" version="1">MGHEDAVYLAKLAEQAERYEEMVENMKVVASEDRDLTVEERNLLSVAYKNVIGARRASWRIVTSIEQKEESKGNSSQVGLIKEYRQKIEAELAKICDDILEVLDEHLIPSAKSGESKVFYHKMKGDYHRYLAEFAIGDRRKESADKSLEAYKAATEVAQTELPPTHPIRLGLALNFSVFYYEILNAPDQACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSSEAEPSTEASAAATEADKGETAAAAAPAEEPKAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1G0</accession>
    <name>A0ABR1X1G0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672149.1">
        <property type="nucleotide sequence ID" value="XM_066808531.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041591"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="68" mass="7958" checksum="EE4848F5E98E36BA" modified="2025-10-08" version="1">MTDKQAKPAEPVTQNATTRYLKKESLQKLLERLFPGQTDFKIRLKEDQWSFTAPTVVKEEYIDGIRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1T3</accession>
    <name>A0ABR1X1T3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Centromere binding protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672233.1">
        <property type="nucleotide sequence ID" value="XM_066808615.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041675"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF70">
        <property type="entry name" value="HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04218">
        <property type="entry name" value="CENP-B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="4">
        <location>
            <begin position="199"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="102"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="270"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="411"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="452"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="342"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="557" mass="60757" checksum="80BBA917C466717A" modified="2025-10-08" version="1">MIGSTGMDQDNLIAHDSTYPNSHWVDVNAYNQMSMPEYSNNFYLAPVTSHGLPSESLGGGHMPPPPMPSQLHQSPIHHQQQLQFPSQQHPQPILQAQKVNWPSLHTNPGQSYSAPPVPIPAQSTVPIRQTPKQLPSITTSQPRKTLSDDDRRRMCQYAADNPKSKQTEIGAKFGVERSTVSKVLRNKDRWLSQEDRSGSPVKRIKGKNVDVERTFVNWMRNQIKKGVLLSDEDMLTKARTFHATTGSSENPAKIITQSWLDKIKRKHNIGPGSMIRRASETAIPDNTRLSRDSPTLSIPPTSGGVSPESPADQSSPPVSATEENDTPSNFADFETSGYKYPHSQSTTSLSSAVTDPSSSAFSGSAFSPASQFTFSPNPDSGLFDQTRPSPGSSHLQRPRSQTLGTLDLDFDQVQSSEPPTPRYSLPATAPPSAVESPAHEIAAPTFGMDAAISPKTLHRSRSNSSLGMRSAGGIISSPASPSQDDARRAAGTLLNWMQNTQSGFVNNEDLYLVLRLTEKLGLQQQIQGPRELHPPPLLGDCRGFRKVTTRSHPSLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1X2</accession>
    <name>A0ABR1X1X2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">beta-glucosidase</fullName>
            <ecNumber evidence="5 14">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_004389</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5 14"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672322.1">
        <property type="nucleotide sequence ID" value="XM_066808704.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041764"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF5">
        <property type="entry name" value="BETA-GLUCOSIDASE M-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 14 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 14" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046105855" description="beta-glucosidase" evidence="15">
        <location>
            <begin position="21"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="16">
        <location>
            <begin position="669"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8089428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="753" mass="80959" checksum="97FCCFD97A283C27" modified="2025-10-08" version="1">MKSLTTALCALLGQSTIVLGQGYTNESEVPLYGLSPPVYPSPKGSGGSSARWTDAYARAQAIVAQATLEEKLNLTRGFVGQCVGNTGSIARLGVPALCFSDAPDGIRGNEFVSAFPAGIHVAATWDRDLMYDYGRALGDEYRGKGINVALGPVAGPLGRVVRGGRNWEGLSNDPYLAGAGMGNVVRGMQDAGVMANPKHWLLNEQEWRRNPGSLGESLSSNVDDRTLHELYVFPFMDGLKEGAVSVMCSYQRVNNSYGCQNSKMLNGILKTELGFEGFVLSDWGAQHSGVASANAGLDIVMPDAGYWGQNLTNAVNNGSVSTERATDMATRILAACNLQKHEPIDVQADHGALIRKIGAAGTVLVKNVNNALPLKKPTFVYVVGYDAQVAASPWQNPSRYGGGYEVNFGWETLKGTLVTGGGSGSSAPAYVVSPFDAIRDRVVKDRGIIRWDFESINPTPYVNADACLVFINAYASESFDRTSLTDEFSDRLVKNTAANCTNTIVVIHSTGIRTVDAWIDHPNVTAVLYAGLPGQESGHSIVDVLWGDVAPSGKLPFTIAKQESDYGHLLNGTVTFDAFPQQDFTEGLYIDYRAFDRDGVEPLYAFGHGLSYTTFEYKDLAVQSEEKTDTRPIPDPAVPVIQGGHPALWDVMAHVTCTVSNTGGVAAAEVAQLYVGIPSNDEFVTPVRQLRGFEKVPVEPGKMSTVTFPLTRRDLSVWDVKAQQWRLQAGSYKIAVGASSRDIKLEGTLEIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X231</accession>
    <name>A0ABR1X231_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxymuconolactone decarboxylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672340.1">
        <property type="nucleotide sequence ID" value="XM_066808722.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041782"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34846">
        <property type="entry name" value="4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34846:SF11">
        <property type="entry name" value="4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxymuconolactone decarboxylase-like" evidence="1">
        <location>
            <begin position="34"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="190" mass="20827" checksum="FC54E71E4ED28A51" modified="2025-10-08" version="1">MRIPYTTDPPPAATSAEDTQIIERPLDLALLHAPPVADGWNSFLGAVRTRTTLSASVRELAISRVAVVNGAWYEWAHHAPLAAEAGVSQKALDEIVKGRPGELNDEAVTPEEREAVGLGPVEWAVLRVTDEMTRNIRVRDETFAELRKHFNEREVVEVVATVSAYNCVSRFLVALDVGEKNGTGPDDTHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2D6</accession>
    <name>A0ABR1X2D6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytoskeleton-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672445.1">
        <property type="nucleotide sequence ID" value="XM_066808827.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041887"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="40183" checksum="57FCD269B4011293" modified="2025-10-08" version="1">MSFFSFARDERLVFAGLGVAAVSVVGMMHLILEYYRDETEIKPQQPKTQYITQETEDALKIDTLNSLITHYNFSIRDTAVKIAAGRAVNDPAIVDQLLWGITREDYEERMRSLRAITFAVEEKDVLLDPLSILDTPKAYSALVRCLELGLDLPGRSQDKLDDPLYDEYYLRDIGERRCILLLHDLLHKHGVDKLVKAKFIEKWLVKQNWGETEEERKSNFANYMKFRKNRIADICHRLKLARIGRRALRNAKLIGRDSAGRLRPQDRAAGSRIKVILEISMSNEDENGEIQQENFQTEFVPRVLEQSAEEQRRRRRHREAIVLNDGTHSLGRDDIIQREHGEHDGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2F6</accession>
    <name>A0ABR1X2F6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin synthesis regulation, Congo red resistance, RCR protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672498.1">
        <property type="nucleotide sequence ID" value="XM_066808880.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041940"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020999">
        <property type="entry name" value="Chitin_synth_reg_RCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187:SF1">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12273">
        <property type="entry name" value="RCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="17121" checksum="42073BD01C01007E" modified="2025-10-08" version="1">MAPFIDQDSLLGKRYYCSSAEAAAGECYRSTWGDYGRWIFAAIVVVFFFFVFFILACITSRRRRRRGMQPMYGTGWMAGNGAGNYQNNPQAYGHQPPPAYGAQNQSYPMNNYQQNGYYSGQNEGVQAPKNVYPHDSTANNATYAPPEGPPPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2P7</accession>
    <name>A0ABR1X2P7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004627</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TLS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672560.1">
        <property type="nucleotide sequence ID" value="XM_066808942.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042002"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010756">
        <property type="entry name" value="Tls1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486:SF2">
        <property type="entry name" value="SPLICING FACTOR C9ORF78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486">
        <property type="entry name" value="TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07052">
        <property type="entry name" value="Hep_59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="227"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="319"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="248"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="357"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="370" mass="40900" checksum="06717C8B7BCF52DC" modified="2025-10-08" version="1">MNPDAPSEAAPETQVLFRGKKRKAHYRQRASDDDVQAPATEVSHNVGNADPAEGADTPLRQNSQPNLHIAAAEEGVSVAELLRRRNARKSRLRGVGFAPKDAQGNDMPTSFEDDLSLMIREEEQKAAVDVSAGDMSKRFSAQTGHVGELVNKHMEDYIAAQLAKRHAPTSLESPAAAQSRSLEHANGSTHAVPKPEGHIAMQGKLLEVDLGDEVRNRNANMTERARRLLAGEKVDDEEPAGPPKKVRLGRDGKPWRPRNRRDSDAMKRDQLVEELMRENRLDMYETPKAPVASTSAEDTAAADDRIAEEFRREFMDAMAARQKRRKAPAPAAKPGAKKDEDVLRGPKLGGSRNTRAAMRDLLLKQEKEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X364</accession>
    <name>A0ABR1X364_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004819</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the secreted LysM effector family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672752.1">
        <property type="nucleotide sequence ID" value="XM_066809134.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042194"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047442838" description="LysM domain-containing protein" evidence="5">
        <location>
            <begin position="22"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="42"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="162"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="264"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="93"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="477"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="500" mass="53915" checksum="ACE0E8DEB6D75319" modified="2025-10-08" version="1">MLSLKATVVFGASWLAQSVWAQDSSPSGPTMPNIAPNCNKFWTVLKDSGDSCWSITQKFGITLDQFYTWNPDVTDDCGTNFWVGESYCVGVDPNKPTTRPSSSSTVAKTSTSSTASSSSRAPNTEPYTTNFPITSWSIAPTTIESSFPPQRTQPGQPPKCNNWYLVNPADTCEMIVSTNSWLTLENLHAWNPTLDADCSGLYAGWWLCIGVPTTSTEEFGWTTTDVPANVPTFAGNYTFTTLPEVDSTFIAEPTQTGIVSGCLSYYKAQDGDTCRSIVDGHFLTEEDFMAMNPALNGNCDGMWLNYYYCVVGPSGITAMPATATSPPATVPSGQNPKCQHWYQRDGESCTDIVAMFGAFSLSDFLSWNPSIGGVSCSGITDGAWYCVGIPGTPTTRTTPLSTTTQPLTPTQSGMVAGCTKLWLVSSSIISANGLSDALFYRWNPAVGSGTCDNLTPNLSIDNQIRHFASSEHDYKGAANQHHRSAYRNTNPNPGGNGIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X408</accession>
    <name>A0ABR1X408_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1941 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673044.1">
        <property type="nucleotide sequence ID" value="XM_066809426.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042486"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008709">
        <property type="entry name" value="Neurochondrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109:SF7">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05536">
        <property type="entry name" value="Neurochondrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="651" mass="71076" checksum="13679A13E15FC8A3" modified="2025-10-08" version="1">MDAQSKPSESHDNGPATNPPQTEQVEKIQQLLRAKDDTSRFVGLALLKSTLDNSEDIRGDKEVIVALWDSISVKFLDRLLKTGAKPGSKQSDAKEMLDLATNVIYTFTVLLPADAVTNSKLVGRIPRLVEAVLCSPGETTDVILKTLLTLTSNPEGGRVFAEAEDWSSLIEIAPKQPYALAILSWSWLHAASSTKDRSSLRDRIDKTISALIASYKGTDAVTLLDFIDKALGRLDDDLIPVNPQWLGPLIELIRNLATARPTAAGREAYTNCTARLLITYSDSVPRLLFRDTSGSENPFSYLFISLIIVDLKATLPSLLSKLNTPEYPSISTRLTSGLLILSYFISFLLQQMDAQINAGSDASSFKDAFQMPPNLLLKLNRSISETLSIIMEYLRDRWDAAVAGALGLHPETRYGKSHTAAGSHLTLAWDQQNESPAEDPLLLAALRVLGEWIREDDGEVLRTEAISLMDLLVELYQTSSGPSSSIGYRALVLGVLQGVTQTEDGIRVLLEHGGWSTLSKDLLATLNRTSSAQTGIDLHECELGSQVALLLMTLTENQQATSEEWLDLVTGIAAYDVPSIGEAPEPLQRFWADVLQLAADLLANTSPGVKRRYEHTAGSIRGIAATVEGRITSPEIQKHLGEALSTLRSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4C3</accession>
    <name>A0ABR1X4C3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Metal resistance protein YCF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_005219</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673152.1">
        <property type="nucleotide sequence ID" value="XM_066809534.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042594"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18595">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="541"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="574"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1025"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1112"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1209"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="314"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="637"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="985"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1306"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="863"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="922"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="864"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="951"/>
            <end position="961"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8090258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1547" mass="171660" checksum="B4B228F158243594" modified="2025-10-08" version="1">MRFDGDQSQQVLHSTGSFTGYRPLLQLGSGYLSATQEFKQPLCGNEEGWGPMSPFRFDFTPCFIDVWVLSVAVFGLVCGPLALWYLLRQSKAVNLAKDWHFWTKQSTLVLVIADVVAQLAIQIVNFPGIWFGDIRVLTTFLTLLSLFVVFAIQWVEHARARNANGVVLFFWLFLLLAYAVKLRSLVSQQVYDSNLAYFVTFAVGVGLSLVDFLFEWLWPKRASAYEALVDDEGEECPAEYATIFSRLTFSWMTPMMKHGYKQFLTEEDLWGLGPNDKSSTTGDNFDKAWKYELQHRKKPSLWLALFKAYGGPYALATVFKVFNDLAAFAQPQLLRYLISFVESYGDGKEPQPVVKGAAIALAMFGVAVLQTSMIHQYFQLAFVTGMRIKSGLAAAIYKKSLKLSNEGRATKSTGDIVNYMAVDAQRLQDLTQFAQQVWSAPFQIILCMVSLYQLVGWSMLAGIGVMIIMIPINGFIAKYMKTLQKQQMKNKDSRSRLIAEIINNMKSIKLYAWSTAFMNKLNYVRNDLELKNLRKIGAGQAFANFTWSSTPFLVSCSTFAVFVLTKTTPLTTDIVFPALSLFNLLTFPLAVLPMVITSIIEASVAVGRLTEFLAAEEVQPDAIVLSPAAEERGDESVVIRDGTFSWNRHESKSVLRDIFFTAHKGELTCIVGRVGMGKSSFLQSILGDLWKEKGHVEVHGNIAYVAQQPWIMNATVKENIIFGHRYDSNFYEKTVKACALLDDFAQLPDGDETVVGERGISLSGGQKARVALARAVYARADIYLLDDCLSAVDSHVGRHIIENVLGPKGLLASKCRVLATNAIAVLTDADYIVQLKDGEVAEKGTFRQLMAMKGGIADLIKTLGQESGPSSQNHSPERSTGSGSSTYVDESAIDKEEAEEAQENVPELAPIKAGGGISAVKRRTGSMSTLRRASAASFKGPRGKLSDEEDPSSKTRQSKEHLEQGKVKWDVYLEYAKTSNVVAVAIYLSMLVAAQSAQIGGSVWLKNWTEHNTKVGGNQDVGKYLGIYFAFGIGSAALTVVQTLILWIFCSIEASRKLHERMATAIFRSPMSFFDTTPAGRIMNRFSSDIYRLDEVLARTFNMLFVNGARSAFTLVVISVGTPAFVALIIPLSFMYYWIQRYYLRTSRELKRLDSVSRSPIYAHFQESLGGISTIRAYRQADRFELENEWRVDTNLKAYYPSISANRWLAVRLEFIGAVIILAAAGFAIISVTNHSGLSAGMVGLAMSYALQITTSLNWIVRQTVEVETNIVSVERVLEYARLPSEAPEIIPRHRAPVAWPTDGAVKFHNYSTRYREGLDLVLKNIKLDIKSHEKIGVVGRTGAGKSSLTLALFRLIEADSGHISIDELDTSKIGLLDLRRRLAIIPQDAALFEGTVRDNLDPGHVHDDTELWSVLDHARLKDHVSSMEGGLEAKINEGGSNLSQGQRQLVSLARAMLTPSNILVLDEATAAVDVETDAMLQTTLRSPLFAHRTIITVAHRINTILDSDRVVVLDKGEVVEFDTPQELIKRKGAFYGLVKQAGLDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8N5</accession>
    <name>A0ABR1X8N5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta subunit of fatty acid synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002139</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673750.1">
        <property type="nucleotide sequence ID" value="XM_066806454.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039514"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03447">
        <property type="entry name" value="FAS_MaoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039569">
        <property type="entry name" value="FAS1-like_DH_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013565">
        <property type="entry name" value="Fas1/AflB-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040883">
        <property type="entry name" value="FAS_meander"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003965">
        <property type="entry name" value="Fatty_acid_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050830">
        <property type="entry name" value="Fungal_FAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982:SF21">
        <property type="entry name" value="FATTY ACID SYNTHASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982">
        <property type="entry name" value="MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08354">
        <property type="entry name" value="Fas1-AflB-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13452">
        <property type="entry name" value="FAS1_DH_region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22235">
        <property type="entry name" value="FAS1_thioest_ins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17951">
        <property type="entry name" value="FAS_meander"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01483">
        <property type="entry name" value="FASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="5">
        <location>
            <begin position="1049"/>
            <end position="1445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8091778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1447" mass="159478" checksum="DBEC85185C7296C5" modified="2025-10-08" version="1">MNAGYHVEFAAGGYHHADGLRQALYRLRDLIAEPGRGITVNVIYVSPRAIAWQIPPAPPAAGRGVSLTGLAVGGGVPSPDVASEYITTLGMRHISFKPGSVAAIRQVVEIARRHPEFPVILQWTGGRGGGHHSAEDFHAPILETYAEIRACDNIALVAGSGFGCAEDVIPYMSGDWSLARGRRVKMPFDGVLFGSRVMTCAEALTSPGAKAAIASAAGVEDQAWEGTYRGPTGGIVSVVSEMGEPIHVVATRGAQFWAEMDKTVFSLEKKKRGPILSAKSDYIISRLNADFQRPWFGRKADGRSCDVADMTYGEVCDRAVELMFVGRRSWIDPSYARFLAEWILRIEERFSEAMEPLISDTLCRDDPIKAVAEVRELFPIAAATQVFSEDAHYFMQLCRRPGQKPVPFIPALDDNFETWFKKDSLWQSEDVEAVVDQDAGRTFILHGPVAARQTCHIDEPVADVLNGINHGVLQHMLQAVRSELPREEFLQSGPGTYPAYSTITHGSADIHPDRKLELLAFTADPSASWLNALLGSPLILRGQDLVANPVRRLVQGLAVSHAEFGREFLRLFTAGNRLDVEICRNGDDIRLAAYTYVTGQSQPVSMLLAFEYRPHSSFAPISEVVHDRNERISSMYRQLWTSAPECMEGQRQALSSPETAVFEDTFVVDAARVRAFNRAIGYTGGHLEGQVPMDFAIVAAWSPICKALLQDPIQGDVLNLVHLSNAYEMTPSHGARSIPMKLGKDLSTRAYVNAITIGDSGKTVEVVCEMRRQALSPVFMTVRSRFLFRGSYADYASTFARKTEPSWEVKMSSKEDVAVIAEKPWLHLEDKNKLNDLDLTDVTLEFHLRTFTKWTDAAHGRVDTSGRVFVRSEAGDLTPIAIVKHSHMGDSRHNNVVLSYLERHGRIVASQRQHVLPTAAATHVSQLSVPASNEQYSRASGDFNPIHTSPLFAHLVDLPGTITHGMYCSAIVRRVVEQHMADQDPRRLKKYDVSFVGMVLPNDTLEVSLRHTAMQAGLKHVEIEVTKTSTAEKVLVGTALVVQPTTTVVFTGQGSQEKGMGMDLYATSPVARALWDKADAYFLAQFGVSILDIVRHNPTEIKVRFGGVRGRMLRQNYMSMHYETPAGVAADGVTEIKAERRPMFPEIHERSTSYTHSSPKGLLFATQFAQPALTIMEMAVVRDMQAHGVLDADGCHFAGHSLGEFAALASFTDFMPFENLLYFVFCRGMTMQSAVERDALGRSAFAMAAVDPSRACRDFAESTLCDLVARIQSQTGFFVEVVNLNIRNGQYVCAGDLRALDLLQRVCDSVKKQAAGSSFSQEELADLTESLIAKLAPTYDGIASASEVQLQRGAATVPLSGVDVPFHSSYLRPRMDAFRRVLLDNLDVARLSPEKLVGRYVLNVTGKPFELSREYFEESLRITGSERIQKVLDEWDTWGAGSARVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA88</accession>
    <name>A0ABR1XA88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674312.1">
        <property type="nucleotide sequence ID" value="XM_066804539.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037599"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045712656" evidence="1">
        <location>
            <begin position="24"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase 3" evidence="2">
        <location>
            <begin position="100"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="247" mass="25604" checksum="6AB12C1DAF09D77A" modified="2025-10-08" version="1">MQFKNAPLFLSLVARSWVGTAAAITAQNDNTAVCGTLADVAQSYKSGALRGDLLLFNGTIHTMDAGETVATVVGIKDGSIVYVGDSAADARKSFLGSPPTIDLGGRVAVPGLVESHNHIVLMGNRPGYHTPLENAYSVADVQQTLAARASRDAVPPGSFITTIGGFHSNQFGERRLPTLEELDAALPQHPAFISIGFNGPSVTNSLGKAYFESANLATGPVAISANGSIAAGDETGKALLTLRQQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB17</accession>
    <name>A0ABR1XB17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NUDIX hydrolase domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000468</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674556.1">
        <property type="nucleotide sequence ID" value="XM_066804783.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037843"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04666">
        <property type="entry name" value="NUDIX_DIPP2_like_Nudt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047198">
        <property type="entry name" value="DDP-like_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629">
        <property type="entry name" value="DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629:SF0">
        <property type="entry name" value="DIPHOSPHOINOSITOL-POLYPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="158" mass="18212" checksum="D70445789ABE2541" modified="2025-10-08" version="1">MASSSTTTDTNGRSMESRTGRSKQPAGSWCRPLTEDKKFVLLIQSTRRKGWVLPKGGWESDEECTEAASREAWEEAGISIQINYDLGDILETRPPKKTHKDPSKSVYRFYEATVLKEEDDWPERHKRERCWMSFAQAKEALEARPELLEALTRSTMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB73</accession>
    <name>A0ABR1XB73_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674713.1">
        <property type="nucleotide sequence ID" value="XM_066804940.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038000"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="225" mass="25982" checksum="768CE0C94C9F0B57" modified="2025-10-08" version="1">MKTAKDFMSPDMDEKEKLLVRSLTAGLSNRRLDMYAKMMEKRQHMKALELMTTFTEMIRQMLFKIMYEEGKTYMLTREYVEWRLDVCLWNHVFGEPLPDWARKEPPTDRGDIHNVDTLYLDFIMGEQLPDPVPTQEATGEEAMKKAAEKRKVEESGLAAEETKARKVRLAVEGNGGVQKEPSIDEFDAEIAQIEARSEKYAEELRALRRAGHDTTTDLGPMNQDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBG6</accession>
    <name>A0ABR1XBG6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674790.1">
        <property type="nucleotide sequence ID" value="XM_066805017.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038077"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="141" mass="15984" checksum="F7E20CD8559D5813" modified="2025-10-08" version="1">MFPPPLVVRNMEIPTASQLPVFAYAQCSLQPHGLAARIKDATILLLALAALVAIVEFFLRGRKTSSRSTRSSQEYQDIDPLPRLDPREKAYIHGMARALLEVPKPRQWDDRPQDDDDDTSGVERIRTRRHGNGRRWGKLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBZ8</accession>
    <name>A0ABR1XBZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000782</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674870.1">
        <property type="nucleotide sequence ID" value="XM_066805097.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038157"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051100">
        <property type="entry name" value="DnaJ_subfamily_B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015399">
        <property type="entry name" value="DUF1977_DnaJ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908:SF3">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09320">
        <property type="entry name" value="DUF1977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="50"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="354" mass="39611" checksum="C4FF6F10880C7C22" modified="2025-10-08" version="1">MPSATASGADAGGANGSAKHREHNQGNQERKYTVEQKAAVLRIRRCQPTAFYDILGIETVKTTCSEADIKKAYRKQSLLTHPDKNGHEHADEAFKMVSRAFGVLGDKEKREKFDRYGTDPDSRFESARAQAGNPFSGFGGGRAAGGGPGAGFGGGNMWEEEMSPEEMFQRFFGGGFGGPFGGFDTGPQFVFNLGGNRGFRVHQMGGAGPRRRPREAAAGPQRETTGWDTLVSLLPIIFLFLFPLLTSIFSGGETQSAPPYTHHRRTPKYHVDYYINPQDVPGWTDHMFKQLDRQAEVKFTNELRFKCESEMRQRQDLYDNAQGWFYQDPDKMRVARAYEMHSCKRLQKMGVPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC42</accession>
    <name>A0ABR1XC42_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">HIT zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000827</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BCD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674915.1">
        <property type="nucleotide sequence ID" value="XM_066805142.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038202"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23023">
        <property type="entry name" value="zf-HIT_BCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051639">
        <property type="entry name" value="BCD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057721">
        <property type="entry name" value="BCD1_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483:SF11">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25790">
        <property type="entry name" value="BCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="8">
        <location>
            <begin position="9"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="218"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="361"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="286"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="436" mass="49095" checksum="051E35A0D165BEF6" modified="2025-10-08" version="1">MDPLLTSLCSVCRTREPKYKCPRCGTNTCSLPCVKRHKKWSSCNGQRDPTVYMPPAKLRTDAGIDHDYNFLTKIERSLEQTEKLLVEERGILPDRAQQNGQSHGPPHKKARLNKGQSRGRTTLEGGSRSWARAAVRKLNTLGITVKHQPYGMTRPKNNTTSFNKRTQTINWQVEWCFLDSAAPSTEKPSLQPEKLLNKTLDNVPMYLAYADCREYHRRSQMSKKEKEQEKKQKQIEDAAADAEETGEDNNGNATFGGQDWKDSTWTAAAVPVQRTDGCWHASTTTGERKPRKLSERQRRAKDTKNEYQFYFHIPGTPSREPQKLIPIDADDDLASVLAGTEVLEFPSIYVTRAGMRLPQGYQLAQRPTNSSTSQDVARLPKKRKSEVLVEYASEEEEGEVAEATGDAELESEMEVDPADDTTSSSGSDSDSDEEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCD8</accession>
    <name>A0ABR1XCD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675102.1">
        <property type="nucleotide sequence ID" value="XM_066805329.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038389"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="33530" checksum="FF25249BCE2F6939" modified="2025-10-08" version="1">MTSPESYPVTKREKSDPPPPVAGSAAAPRGGAATQSPPVEFRGFDFFTKREFNELKSASEAYFAPAAAASSRASRRLSRALGPASWLRDPTPPEVPPEGLPPAEGRFPIPMGGKNELPPLTNASDTWSRKSTTRFCGLRRSRFWMIIGLLIGLVIVVVAVGVGVGVGKNASGSSSDAAGAVSSGPSSTLSHPTSTATTTATATVSPTATSTSTSTNPAATAGKLDCPAANGTEYMVPGSNKRFLRVCGVDYTGASGGVDLKQVTTQSMLDCMTNCAGTYGCTGCGWGYMEGDTGYEHRCWLKSKLMKSHETDINWSFAVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCJ3</accession>
    <name>A0ABR1XCJ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675193.1">
        <property type="nucleotide sequence ID" value="XM_066805420.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038480"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003560">
        <property type="entry name" value="DHB_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669">
        <property type="entry name" value="5-KETO-D-GLUCONATE 5-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669:SF4">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01397">
        <property type="entry name" value="DHBDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="222" mass="23836" checksum="E5D939667983AC9D" modified="2025-10-08" version="1">MATVLIIGAGPGIGLSTARAFQHAGYSVAIASRTRQQKADPSMRHFVFDAAKPDTVKTLFAEVTAAIGPPKVVIYNVAQRFATEPEEPFGLDPDQVQETLAVNALSAYAAAREAVKGFVKTGQGSTFIMTGNMLNTVALPGILCFGMGKSAAAHMIQNASISYKNKGYKFYYADQRQPDGGPTIPVDGEAHAKLYLDLVKDTEQKPWDYTFVDGQGYVSFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCS9</accession>
    <name>A0ABR1XCS9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nup93/Nic96-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001163</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675251.1">
        <property type="nucleotide sequence ID" value="XM_066805478.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038538"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="283"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1049" mass="116175" checksum="96B182B772116503" modified="2025-10-08" version="1">MSGLFGGKPSPFAASTTPATTGSSLFGSTTPAQPSQNTANPLGQTPKPGGLFGGLGSTTNQQPSHSPFANTTTQPQAGASVFGSALAGQNQPTNPSPFGSLGLSTNNQATPGLFAASQQQSTGNATNAQSQGPTTGYFDSLLAKSKKQAAGETALEDLPSLQLGLGDLRQKLRNLGPRAQDPLQSNRAQYMLAASGVDPGAAVKDLNYFDIQAGRVERPTSNAGPSELDVDTYLANLQTKTTLSMIAEGLERSAKEFDNFLEDNITMEWDAQRKRIYEHFGIQTRDSGPDNNAGAPKESVGGFGRSRRTKAARSTPTGERASTFCKIGSHQPEFTDVENQSGKKPAMGGAASVDDRFLREKQGKLADKIRELNRHRLEQRPYPLLHELSDVESRSGDRHAQQVVEAYQAVISIVATPHKPWRYARGFSKGANGFLENKFFTEVETLITKYPREANLGGRPDVVSKIKAYVRLRHARRDLVPDNTELQQVGGEYIWALIYYLLRSGHVTEAAEYVKAHSTIFRTIDRTFSSYLLEYASNEDRRLRRQLQERCNNEYTQRARNAPENSIDPFRMACYKIIGRCEINNRQLEGLNTEINDWIWLQFNLARESDKTGDLQSESFTLIDLQQTIREIGAKHFPKTPAEDSNGTFGMYFFLQVLSGQFEQAIQYLYPFSYVDAVHFAIGLGFYGLLRPADPFANPNDLVTFNTRNQAQVSFGRMLGYYTRDFRAADVASAVDYLALMCLNADLDGDAGSQQAELCHLALRELILETREFSKLIGDIRPDGRRIVGLVEERGPLIGLREEDDFVKAVTLQAARYADDNGRTTDAVLLYHLAEDYDSVVTIVSRALSEAISLDIGEDPLRLQPVKSRAGGREDEVQPGSSLSLASIDDPVDLARTMMGMYEKDAMFYTKIEEHNRIACHLLLQMSEIKGMVESGQWSESLDRIRVLEILPLDANGDPAIIRHYASKFSGLSQSVSMNVPNLLMWTLACCMRQKERLMSGQYSGNEGARRTMFMNLKQMTMDLTTYTSQLKYRFPPHIHQALARASAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCT2</accession>
    <name>A0ABR1XCT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuc-1 negative regulatory protein preg</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675239.1">
        <property type="nucleotide sequence ID" value="XM_066805466.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038526"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219:SF1">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046424299" evidence="2">
        <location>
            <begin position="22"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="23000" checksum="B27D99F3D130EEF8" modified="2025-10-08" version="1">MRTPTTLFVSSLAALAGLAAAAERTVPIYIQPVAMSPPAPVLLGEVVYDEALLAGADPASAARVTSFEYPSDLLSPDDESDEQTEVPRKVRVGAWDPAAKSWASSTSLASTANFDKGFAPHFVLTVDSSSGGDVVGVVLKGVRIDAGQTRDFGPQAVLRTAEPGSQIELNKPVVLSPEGRKVAEEPEKTLLQKYVFTYWWIIGIVLMLTLTGGGGEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDG7</accession>
    <name>A0ABR1XDG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphatidylinositol N-acetylglucosaminyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GlcNAc-PI synthesis protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_001364</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.198" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675452.1">
        <property type="nucleotide sequence ID" value="XM_066805679.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038739"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03796">
        <property type="entry name" value="GT4_PIG-A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039507">
        <property type="entry name" value="PIG-A/GPI3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013234">
        <property type="entry name" value="PIGA_GPI_anchor_biosynthesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08288">
        <property type="entry name" value="PIGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="9">
        <location>
            <begin position="45"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="8">
        <location>
            <begin position="216"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8094679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="485" mass="54195" checksum="4CE3CC990B8C31F2" modified="2025-10-08" version="1">MPRLTYNIAMVSDFFFPQPGGVESHIYQLATKLVDRGHKVVVITHAYADRKGIRYLTNGIKVYHVPFAIIYRSATFPTVFSFFPVFRNIMIREQIDIVHGHASLSSLCHEALLHGRTMGLRTVFTDHSLFGFADAASILTNKLLKFILSDVDHVICVSHTSKENTVLRAALDPVMVSVIPNAVVSENFRPRKYPPEPPAPNNGFGNATPAVHHLGPNDPVVIVVISRLFYNKGTDLLTASIPRILENHPNTRFIIAGSGPKSIDLEQMIEQNVLQDKVEMLGSVRHEQVRDVMIRGHIYLHPSLTEAFGTVLVEAASCGLYVVCTAVGGIPEVLPGHMTVFAKPEEDDLVVATGKAISALRANKVRTEKFHDQVKAMYSWDNIAKRTERVYKGIMGDIPEADFYGYDVGNTAAWNGESHSGVRSFALIDRLKRYYGCGVWAGKLFCLCAVIDYLLFVFCEWVFPRDHIDIAADWPRKIYHSDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDQ0</accession>
    <name>A0ABR1XDQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675582.1">
        <property type="nucleotide sequence ID" value="XM_066805809.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038869"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047365109" description="Secreted protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="16386" checksum="AFC0E97ECFD80459" modified="2025-10-08" version="1">MSRSQNTALVFVAVALLFLFWKNSAADSYSLTGPPASASVMGSNLEVSIRNAGEHKLALGVTNKGDKPPDRDLLELPAGPDRTQARTRRMPPESDSLVTIKPGEKKDNVLEGTWMGVWDADGFKTEELESIGSAQEAQFGDFKAELESVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDR3</accession>
    <name>A0ABR1XDR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001456</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675544.1">
        <property type="nucleotide sequence ID" value="XM_066805771.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038831"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="324" mass="35456" checksum="4FFAE3E1A6E8521C" modified="2025-10-08" version="1" fragment="single">PDLNINHHVPPTPPRPHQTQPRHLLRHPLPHPPRKLRPRQNHRRHRRRHRHRRRDRARFFAAAGASRILLMGRRPDPLLATKASIEAAHPGAEVVATPADVTDKAQVDAAFSDFVGDDGDKKIDVLISNAAAMGPLEGIDDVDPTAFLAGVQTNVGSALLVAQAFLRHAAADAVAVNVSSNAAHVNFARAFVSYSVGKLAAYRVWDTVAFAHPEMRVYHVQPGIVDTDMNRSAGGVKALGYEDHANNLSLSVSLPAGFMLWLASPEAAFLKGKFLWSNWDVDELKTRASEIEASQEFNIQVVGWPFGGPAEVTMASDAADHWKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE45</accession>
    <name>A0ABR1XE45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7143 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675586.1">
        <property type="nucleotide sequence ID" value="XM_066805813.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038873"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055567">
        <property type="entry name" value="DUF7143"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37592">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37592:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23631">
        <property type="entry name" value="DUF7143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046853166" description="DUF7143 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7143" evidence="2">
        <location>
            <begin position="57"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="216" mass="22458" checksum="73BF7A17404C2E0C" modified="2025-10-08" version="1">MQYSTTFTVAALFASLAAAAPANHVSFVTDKAIIDTPTDVKPAVELEARQNGGACFITGNAQLPAEVATVVQQLGPKVKCNAGLKTLGGVPDVTSGGQTYSKIDFSKSGTSGLQFALDTFVTADCMADSNLQAFQDALDVYTATEAGLRSSGGNFNTIKAPKFFLAMQISRIKTAQGNPPTDAANQVAHLAEKVTKNAGRVDQSLIAKVNALAKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTD9</accession>
    <name>A0ABR1UTD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase type 12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660797.1">
        <property type="nucleotide sequence ID" value="XM_066818609.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051669"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 12" evidence="2">
        <location>
            <begin position="56"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="264" mass="28757" checksum="60E468CAF7E14DC8" modified="2025-10-08" version="1">MANTPSGATVDKVKQDYDEQASMYNVLLKWPFGQLESQLFASAVGSDDFCRGATVLDIGGGTGLRARQALEAGAARVDVVDFSDEMMAVGRRDAEALLGPEESAQRLRWFHGDATKPLFGTTTETERVEGLAGLSPPYDVVMANWIFDHVDKPEVLEALWRNIAAAVKPGGRFIGVRACDPRCEAMSSGNSTIPSTGDGRPAIHLENASLEVSYSGSTEMHERHGFTDVEIEPCEKQGVVRADPGFWQLWINKPGFVVVKARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTF2</accession>
    <name>A0ABR1UTF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-taxilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660812.1">
        <property type="nucleotide sequence ID" value="XM_066818624.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051684"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="384"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="301"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="384"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="454"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="54436" checksum="3FA2D799AB241501" modified="2025-10-08" version="1">MDSSETSKLLAARISQLEVDNAAEKEQEAEIEREVRKHTRDLNNSLNSSSGKMNDIEKIDLLTKRWSELFAQMKRHERDSIKNKKRADQLQKDKDSSRTEASKLTGLKEKLEKLCRELQKDNNKLKGEQRSLKDAHDKLRKDSDKRMEEVFKTLEGYQEEKDNPRKQVMNTKVEDLFKNRFKSLIEQYELRELHYHSLMRTKEIEVQWNMARYEQQKKAAESESARCRQLNSQVLTFSKTETELRNQLNVYVDKFKQASSDLSSLLLNQALGLTLNSSAVLQVEDTLNNSNDLFLTFRKEMEDMSKKTKKLEKENETLKRKVEARNQNIVKMADERQKHVKELDDIRKKNEKLTSIINQMQQQGRGIPQGMQGTVEDSCYAEGEEVHDDGGDELEDEEGDEESEYEYEEEEGDFGSEEVEFDDDTEEEVHLHSLPPVQAPTAPTYGPEPPPTHPAAQAAAAAATAPAINGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTH4</accession>
    <name>A0ABR1UTH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_015334</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660533.1">
        <property type="nucleotide sequence ID" value="XM_066819648.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052708"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="757"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="802"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="873"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="905"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="986"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1022"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="65"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="401"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="762"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1100"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="708"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8061113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1328" mass="143933" checksum="0895DDDACDEEAB97" modified="2025-10-08" version="1">MAEKDDLQGQKPADAAADAATNDGNGVEVASKPRSKLSRFFRHFFRYFRLLGYAEPGLVDIGLLIAGTLSSIAAGVPFPLIGIIFGQLLDNLNSATCAAGDAATDAAQYQASVNDKVLKVFYLAIAQFVLIYIYIVSWNLFGDRLAHRLRAKYFRSILKQEVSFFDKLPAGEVSSRLSGDISIIKAGTSEKVGLVLGVLSMFVTAYIVAFIKYAKLAGILVSLLPAFLLMGILGGHYVGKFSGLVSGHIAAASSIALESLSNVTIVQAFRANDRLEKKFTEKLTDARRDGIKKAVATAIQSGMLYFLAYSANGLAYWQGSQAIADVVSGRTTGMSVGTTYTIIFILVDGTIVLSQMAPFLQIFGSAAASFARLEEDIGRLSSIDGTVDNGVDSSELVHGDFRLENVSFTYPSRPDVPVIRDVSLHFPKGKRTAVVGLSGSGKSTIAGLLTRLYDPDGGAIFVDGRNLRDLNVRQLRSHIGLVQQDPLLLDRSVLENIALGLINSPRPAHHDLQEFLLGNGLAEIAEQVRKGTDLQTAAAAHGQQAVQIVEMVQRATTMADATAFLGHLEYGYGTMVGSNGDLLSGGQKQRVALARALVKDPQILVLDEATSSLDSGSEQRIQKAIEEVTVGRTVVSIAHRLATVKSADNIIVMRNGRVIEQGSHAELLAKDDAYAALVRLQNMGSDNSSIATSKVSKDPEMDPEKVIEPTLADDPVKSPETVMNEPASRTPSEESKPTTKRTTWGNMKTMHKFTRPFFLLLLVAFTSSLVVGGAYSGAAVIFGHTVEALSPCEGEDSIRSAGSFYGLMFFILAIIELFANGISWSSFGTVAERVLYSIRTLSFRSLLEQDLHWHQSEDRTPSTLLTFLTNDSIAVGGLTGSIIGTIFSIGVNFIVAVILSHIIAWRIALVCLAVVPLMLGAGIMQIRLLTQFAARHETAFAKSVSITVEAVNSIKTVAALSLEQEVLGTYRRSLKTPRKEMFRSSIWINLWLALTNSISNMIYALAYWWGAKQIIEGHYTQTQFFIVLIALLVSAQLWGQLFTLAPEVTNAGRAASRIFDVIELGSNQSMEQKKYVAHDDAEAAAESKVASPTKEGGMSISFDNLMFSYPARPNRQVLKGLDITVRPGQFCALVGPSGAGKSTIIALLERMYRPDSGCIKIDGVDIAAKSEPLFRDEIGLVPQDSILFDGTIRFNIALGARPDHEPSQAEIEAACRLANIHDTIMSLPEGYETPCGTGGSQLSGGQKQRLSIARALVRKPRMLLLDESTSALDAESERLLQEGLHTIRRADVIFMIEDGRCVERGTHEELMRKSESYRVNVLHQTLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUU3</accession>
    <name>A0ABR1UUU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014793</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661295.1">
        <property type="nucleotide sequence ID" value="XM_066819107.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052167"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="229" mass="24859" checksum="3C70596D22D7B131" modified="2025-10-08" version="1">MVSFKKIFALSAAFSASRSAAASLSPPAAATLDVVAKRAPRRQMLQWSPSGTLVYLLGAPIDAFAQLPAELRNLITGHGEGGPAQMLLYNWVEFVKSHVSQYRAAYNLYLDHMFNVGAQVGGVYGQGQAANLWGFGFHFAHPPSAADLQNLRDAIQAWGQQEGGAVNVLQRANGFFNPADIGAGLRRRSRDDHCPKPVDVLKYAKRDVPSDLDFKKLTRWAGMCDGMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVB8</accession>
    <name>A0ABR1UVB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661479.1">
        <property type="nucleotide sequence ID" value="XM_066819291.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052351"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="206" mass="23775" checksum="2C6A3A61B8245777" modified="2025-10-08" version="1">MAKFTLFPRLARELQIMIWEEVLGGETDDRIVFVHRDSLRIMPVAGKRLVSPLLSVNRQSRAEALRRYSCRLDIMKVPTSPMPIQSVERWASERGLSDKHTKEGLNERYWYSREAAETYNNIEENLKTQLDTIGTVKGCVYLNPHADKFLLSYHEIYDVHCTDDCCVAALAYHKKSKKSLMFCEWEMVEDSSDPNSWILSGKPGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVL3</accession>
    <name>A0ABR1UVL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Elongator complex protein 3</fullName>
            <ecNumber evidence="15">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_014804</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>uridine(34) in tRNA + acetyl-CoA + S-adenosyl-L-methionine + H2O = 5-(carboxymethyl)uridine(34) in tRNA + 5'-deoxyadenosine + L-methionine + CoA + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:61020"/>
            <dbReference type="Rhea" id="RHEA-COMP:10407"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74882"/>
            <dbReference type="EC" id="2.3.1.311"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:61021"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="15">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the ELP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="15"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661306.1">
        <property type="nucleotide sequence ID" value="XM_066819118.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052178"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034687">
        <property type="entry name" value="ELP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056591">
        <property type="entry name" value="ELP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01211">
        <property type="entry name" value="ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23613">
        <property type="entry name" value="ELP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005669">
        <property type="entry name" value="Hist_AcTrfase_ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01086">
        <property type="entry name" value="elongater_protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00344">
        <property type="entry name" value="ELP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 15" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 15" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Radical SAM core" evidence="16">
        <location>
            <begin position="100"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR005669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8062707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="574" mass="65036" checksum="BE5259F86E7D8760" modified="2025-10-08" version="1">MATTTVTTTATIRKKDANLPPENERFLRCCADVANALIEDYESSKDPKAPKKDINLNSLRAKLSRKHKLPNLPPLTAIIAAVPEHYKKYILPKLVAKPIRSSSGIAVVAVMCKPHRCPHIAYTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFEQARGRVDQLKSLGHSVDKVEYIIMGGTFMSLAPSYREEFISQLHNALSGYQTNNVDEAVEAGEMSNSKCVGITIETRPDYCLPSHLTDMLRYGCTRLEIGVQSLYEDVARDSNRGHTVAAVAETFCYSKDAGFKVVSHMMPDLPNVGMERDMDQFREYFENPAFRTDGLKIYPTLVIRGTGLYELWRTGRYQNYTPNALVDLVARILALVPPWTRIYRVQRDIPMPLVTSGVENGNLRELALARMKDFGTTCRDVRTREVGINEVKHKIRPNQIELIRRDYTANGGWETFLAYEDPKQDILVALLRLRKCTEKYTYREELTDQQTSMVRELHVYGTAVPVHARDPKKFQHQGFGTLLMEEAERIAIEEHGSAKISVISGVGVRSYYKKLGYWLDGPYMSKWLDGRPQPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVM0</accession>
    <name>A0ABR1UVM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inversin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660720.1">
        <property type="nucleotide sequence ID" value="XM_066818532.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051592"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="185" mass="20540" checksum="4BF1EFBBA7A1B10A" modified="2025-10-08" version="1">MSSTSKDPSGPTGKAHGDPPGEDRQSLTTGSTRLYREALARFTTKAEREWRDDKARRLLHQFLCERDTPERSWAAAKNLKQDSSLKCGDHHIAGGIKIRGAWIENILSNIQSFISVGNYAMEHAPESLGLAWFAVSFALKAIQSDFELYGLFGSGLTDITEIMIIIPPLRPTVRRGVQNSRLEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYL4</accession>
    <name>A0ABR1UYL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prolyl aminopeptidase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661498.1">
        <property type="nucleotide sequence ID" value="XM_066819310.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052370"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF11">
        <property type="entry name" value="ESTERASE_LIPASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="6"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="237" mass="26050" checksum="CB1EC99810C4F059" modified="2025-10-08" version="1">MSKPFFVFLHGAWHTPKCFMPLTSALQEAGFENRVVCPALPSSNATPLPTDWNADVETIRTTVSKLVEEHDVVVVMHSFSGFAGGVIRLVYIAAFLVPEGFQHSPAGTRGNMVPQMKTDMDAGSITILPEDAKNMFYQDVDDTTAAELSKDLRPQSLGAYWGKTTFAAWRYIPTTYIICKRDVPTTVAAIHWLIDTAKASGPHQIDSVIEVDAGHSPFVSKPQWVADTLIAEVNRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UZ62</accession>
    <name>A0ABR1UZ62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661708.1">
        <property type="nucleotide sequence ID" value="XM_066819520.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052580"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="27"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8063109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="252" mass="27917" checksum="C61735923C356533" modified="2025-10-08" version="1">MHAASDEAEPSHQLLGPSEDPKTPLIIYFHGSGESCEPAWSELARLLSSKYRVLLFERGSLNPKPAEATSQLLQYLKTKDLPSPYILIAHSYGGAFARTFMHQALSDVAGAVLVETGQEGGLDPKIAAAQAQKRVLGVKPLSVIRGNSFIGKQKELEASENTAQTEQQKAAFAVQWQLLRASDEEDERMKKAQLALSKNSRYLHIPDCGHHVIRDRATVVAEEVGWVMANVADVRKSTRWQKLAIKLQNIWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2J1</accession>
    <name>A0ABR1V2J1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Non-homologous end-joining factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_012161</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the XRCC4-XLF family. XLF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662167.1">
        <property type="nucleotide sequence ID" value="XM_066816475.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049535"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22285">
        <property type="entry name" value="HD_XLF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.210.10">
        <property type="entry name" value="DNA double-strand break repair and VJ recombination XRCC4, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052287">
        <property type="entry name" value="NHEJ_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053829">
        <property type="entry name" value="XLF-like_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015381">
        <property type="entry name" value="XLF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038051">
        <property type="entry name" value="XRCC4-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32235">
        <property type="entry name" value="NON-HOMOLOGOUS END-JOINING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32235:SF1">
        <property type="entry name" value="NON-HOMOLOGOUS END-JOINING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09302">
        <property type="entry name" value="XLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21928">
        <property type="entry name" value="XLF_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XLF-like N-terminal" evidence="9">
        <location>
            <begin position="7"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="XLF-like coiled-coil region" evidence="10">
        <location>
            <begin position="130"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="274"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="377"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="484"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="540"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8065414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="567" mass="60735" checksum="4C215D389E72E250" modified="2025-10-08" version="1">MKATTLKWVPLPAFENGIPALIVSPNFGTNTYKLHVSDLANVWTESLERKAIFARSIQEDTSIDLTEGPDQMTILLNYLQAAFDTSSPQHHQTKLTLEAAPNGGLVLLITCTLPGGLKPLKWPVNLTKQSPASLASELVLPLVQSQHARAREVDNLIAALHQKDAIITKLVDKLEAMGTGLEYVFNALPGKRKISRVAADTKVAGLAPFEESEWRLVMSQGTPAPVDVSSLVQEVLGGSKAVHLKESGICASDDLNGWWEHMGTGPVPTLIQQSTEAVEGGEKEEALQKEETPTDDDDDFQVQATPPHLASKRRQQHGAIDDDGTTEDDGSDAGPSSHPTLRKEGKKPPPRRIGTIGSRGASQQARSSSANQSSQSVTAVDNDNTASESDAEPVKPSPKKGPVKKIGLIGKKRGSTPRPVKSPTPTPAQPSPQDDDATASDDGSKKEKSPPPSLPPKPAPTQRKKGGLGTIGGRSKTMARHTRSPSLEQDKGVTTASTAKPKAGRLGVIGKRRPEEQAQQSGSKHAGQELSEESETEEQVAERRRAELAKELERKAAAAPAKKKRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2R4</accession>
    <name>A0ABR1V2R4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tyrosinase ustQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012235</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662241.1">
        <property type="nucleotide sequence ID" value="XM_066816549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049609"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046773187" evidence="3">
        <location>
            <begin position="21"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="327" mass="35599" checksum="F0AC92334CD7192C" modified="2025-10-08" version="1">MLKLASLATLLLAAAHSVSGACNNPSVRKAWNALTDAEKHDFLQAEVCLMETPSKTRFAGSVSRWDELQALHTAQVQYIHATGSFLPWHRYFMTVHEKLLRSECGYKGVIPYWDEQADQAAAPLYASSIFDAATGFGSNKTDANGCLVDGPFVNVTNTLLSNFTRGPPQCMTRALDQAQFNLVAQAKVDLCYAAATYVDFNACIGGDPHVAGHFAVGGIMLDVALSPMDPLFFAHHTNLDRLWWTWQSKDLGARLADMGGVNVAIFSVLTQAQPKSLPADAFVPFFGDDGGSVTTLNHRLWMAGILPNITIAEVMDIHSEVICAEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5G3</accession>
    <name>A0ABR1V5G3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM5</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_013180</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663186.1">
        <property type="nucleotide sequence ID" value="XM_066817494.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050554"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17756">
        <property type="entry name" value="MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008048">
        <property type="entry name" value="MCM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054125">
        <property type="entry name" value="MCM5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF42">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21933">
        <property type="entry name" value="MCM5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01661">
        <property type="entry name" value="MCMPROTEIN5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="319"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8066433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="720" mass="80238" checksum="9F66375684E6B960" modified="2025-10-08" version="1">MDRQSVFSVSVFNSEAGQSEDSRTQVQEQLMQFVLSFRLDNKFVYRDQLRENALLKQYYCDIDIGDLIKYNEELAHRLATEPAEIIPLFEAALKKCTHRILFPHEPKADIPEHQLLLHSTAEDVSIRNLDSMTIARLVRVPGIVIGASVMSSKATELAIQCRSCLHNQTIPIFGGFTGVTLPRQCARQRAPGDGAEKCPMDPYFVVHEKSRFVDQQIIKLQEAPDQVPVGELPRHVLISADRYLTNRVVPGSRCTVMGIFSIYQNKASKNAGGGAVAIRTPYLRTVGIQTDVDSTAKGHSSFSEEEEQEFLELSRRPDLYNTMADCIAPSIYGNRDIKKAILCLLLGGSKKILPDGMKLRGDINVLLLGDPGTAKSQLLKFVEKVAPISIYTSGKGSSAAGLTASVQRDQSTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTILNARTSVLAAANPIFGRYDDMKSPGENIDFQTTILSRFDMIFIVKDEHTREKDERIAKHVMGIHMGGRGLEEQTESEIPVDKMKRYLSYCKSRMAPRLSPEAAEKLSSHFVSIRKQVHASEIEANTRSSIPITVRQLEAIVRITESLAKLTLSPIATEQHVDEAIRLFLCSTMDAVNQGGNQGSRELNEETNRVESELKRRLPIGWSTSVATLRREMVEGKGFSEQALNRALMILQRRDTIMFRNQGAQVYRNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5Y4</accession>
    <name>A0ABR1V5Y4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662217.1">
        <property type="nucleotide sequence ID" value="XM_066816525.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049585"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35419" checksum="4441285C84153730" modified="2025-10-08" version="1">MSTSSSAPANAKPALEAAPERPKPHARPPLIATLDQAALAGTKSTPTNNAYKYSLDAKTLQEESRRLLREQPPTTKDRFICYLLNGTDALSNIGRYCERESFEEKFRLDDALMHKMYGAHEEASIFFLAMDQQDAAPVGVIRIIRNAPGRAGLLTLNDCHEMLGVTIYQFQAHHGVRSLDDVWDIGSVVVRKQYRSTDRNLASNLLFRAMHARAGHEGVVHYIGTVDRDIRRMIQLVGFWGGTICDTGPVSHSGSDDSLFSYGHWATINANVKRRVGEVPAEVRPVVELFARRCIDGEDMDHRLMFDISKAPTTGLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V695</accession>
    <name>A0ABR1V695_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662261.1">
        <property type="nucleotide sequence ID" value="XM_066816569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049629"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="365" mass="39245" checksum="6BD91E9C0E5563E7" modified="2025-10-08" version="1">MFTAAYTWTLELFAGDLDPAAFSGPLSGEKWAPLRTHPRVSRLIPLPLSNSAEAKRMRVAALAGILGWVCAQHIFQPTYLLQCNELCGVLASLADDDHGRETYLRSVLLPVSPSRQKENGKKRIQQAVFDILACVAPLLPKSRQEDVKSSLEAVCKHICGQWMRLQLLEEKIEPSFDAYDGDDWKLIELPAFGGSVAALPPHDHNADGGGGGGSSSGESTGTCAVAEEGISDIEDIAAVLWPSFLSSRDGESELLTEGVVIAKAQTRAAYHEEKAGLLLGYHRAARQIARKDRTKSFATAGEEMSGAKDFCALAPAVDAKAGKRKTGMRDDDAVVLGRDLSAGLVDLGCMMVLGYCVFLFVSIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6P5</accession>
    <name>A0ABR1V6P5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PG997_012390</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HRD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662396.1">
        <property type="nucleotide sequence ID" value="XM_066816704.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049764"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16479">
        <property type="entry name" value="RING-H2_synoviolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057992">
        <property type="entry name" value="TPR_SYVN1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058051">
        <property type="entry name" value="Znf_RING_synoviolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF184">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25563">
        <property type="entry name" value="TPR_SYVN1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="19">
        <location>
            <begin position="345"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="406"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="684"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="520"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="406"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="699"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="728"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="747"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK8065643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="811" mass="89146" checksum="5FA13953880C603F" modified="2025-10-08" version="1">MRILWYAGASTALAVGVTTYAFQQRANFYSAMVYLSQNNLSLMILINVILLMYGTFVYSLQRLCYGQLRPTEVEQLYEKAWFAVTETCLAMTIFREEVGAWFLVMFTALVTGKIWQWIGEGRVEVLEQQPPANPRLFHTRLSISLIFSILYDTWLFAYAVNTVIQQARPNMMVMFLFEFAILTTDSFRTALRYVLSLVETSITKKQTQQRLEERRKQVRDQRTEILRLRESGDAAEAEAANQQELPDEEDIDEMDIEVPGWETKGQWILSLELVADFVKLGVYAAFFAVLMMFYGLPIHIMRDLFMTTRSFLKRLSALIRYRKALQDMNKYPDATEEELGRENTCIICREDMRPWDPNVTGAVERSRPKKLPCGHILHFGCLKSWLERQQVCPTCRRSVVMDGGMPNGHAAAPNAGGQQPAPGQPGANNGAANGNQGGQGRPGGMRMFQLGPLRLGFAQGNPQNLQEIAQRFGMPLDGVNAPAPAVNPAGAAIPVPMAAPAVPQPPHEVTANTDRANDMAAQLQDIAQRLHQEMQSLQATQAELQTLYAMRAELNRLRQLQHHTSSMHVPAQNDATHGVPNLQVPFPAQMPAHQPLASFPIMPQMAQFQYPPRIGTPSVTRHAAGSWSTTIPAGSPDLPEGVVIPQGWTLMPLQRLDPQAQPSTAQMPMPQTETVELSQQGANLGTAGAASASGEIPRSTSTGPSTSQTQQETSSATSTEQNRGGAEPPVVAAPQPVAPNWGGAAQLFSNNTPSTSSLFPGSNTDHSSRPNSTDGGHSDNEQQHQGSSPESPDKGKAKAVTVEDAEDAEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7L9</accession>
    <name>A0ABR1V7L9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013930</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EMC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663936.1">
        <property type="nucleotide sequence ID" value="XM_066818244.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051304"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039856">
        <property type="entry name" value="EMC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055217">
        <property type="entry name" value="TPR_EMC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12760">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22890">
        <property type="entry name" value="TPR_EMC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="EMC2 TPR-like" evidence="6">
        <location>
            <begin position="113"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="326" mass="35589" checksum="C6113B934C946486" modified="2025-10-08" version="1">MTSSLLRPPGHLSPATALQLSQQAPIIIKNSPGAVTASALSSLFSAPETPELWTIYENLLLSCLRTGDEESAHLCLGRLVNRFGDDNERVMALIGLMKEADATDDATLEVVLKEYEALLQENPTNIPIVKRRVALLRSIGRISDAVTALIGLLDFSPTDSEAWSELSDIYFSQGLYSQAIFALEEVLVLQPNAWNIYARIGELLLMSVKSGSGDQNDSAKQLGEALKRFCRSIELCDDYLRGYYGLKLTTTQLLNDPPKPSKQAESDGLAPPNLSTLQKLDGLATEKLGEITRRFTAGEKGWQGFDEAEIAAAKELLEKSSSTTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7W8</accession>
    <name>A0ABR1V7W8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">YTP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014039</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664045.1">
        <property type="nucleotide sequence ID" value="XM_066818353.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051413"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018825">
        <property type="entry name" value="DUF2427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018827">
        <property type="entry name" value="YTP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_6G12730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685:SF2">
        <property type="entry name" value="PROTEIN YTP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10348">
        <property type="entry name" value="DUF2427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10355">
        <property type="entry name" value="Ytp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2427" evidence="3">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Protein YTP1-like C-terminal" evidence="4">
        <location>
            <begin position="105"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8067292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="46430" checksum="7711B7C5E4B29BB2" modified="2025-10-08" version="1">MVAWGVIFPAGMVLGIVKSRWHVPVQSLGGVLALLGYFLGHMHGGREFGSNIHSIFATPLMFMLLGQVVMGIYLKLHLEKGFHGKMRRYVKLGHSILGKAMPVLAWTQMVFGGIATLGFCHGDHLGQCLAHFIMGSSFIAYGILSAIVLLVGQAWLRRTGRSQEFFDSAMIAGWGCVNTFTEHRWGGAWVENDWQHTTMGVIWWCAGLAGIWLSKDRTGRPQRNFIPGFVLLITGWAMSSHPQHKMVSSQVHKIFGYTLMAAGATRIIDVSFVSPDGVPEDGRPPRNFEYISVFLLYASGTLFMAATEEQMELIENSGMDHVAYILILYSIAFLVFLFSMMLINLYDQNANPAMAKKDLANGRMGTGPNGHVPVRDAQEFELEGLMSEDEDAEGNRLLRDEDLPLDSPSTVGKNSDKVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8Q2</accession>
    <name>A0ABR1V8Q2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663434.1">
        <property type="nucleotide sequence ID" value="XM_066817742.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050802"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="2">
        <location>
            <begin position="331"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="455" mass="49463" checksum="783049ECEB0F5F64" modified="2025-10-08" version="1">MSSSTKPLLVLTCTPGAGHINPIKGLAQALVLDGYEVTVVSSSHYQSVFEGVGCGYVAVQGYGDYWDEDRDAKWPERALIPPGPEQFSWTMEHSFIRVIPDQFAAIQKAIEMLREKNPDRPVVLLNESGFLGALPIMRGAKGPKPDGVIGVGVLLVSLNSVDTAPFGPGLPPPTSAAEVAQYAETRKHIDGLIWEKPLKVCRDIMGALGAQIPDDEALSPDVVYFWPDRFLQLCPPSTQYPRSDAPKTFHFTGRLPQLPKEPGASAVEKPVWWDEVVESPAKKDIILVSQGTVELNYENLIIPTLEAVKDRPSTLVIVVLGVKGASLGPDVTIPDNTRVLDYFPFDDILPHCSVLVHNGGYGGVQHSIRNGTPMVLAGETEDKPEMCAIAAWAGVAINLKTGKPSKVALRTAIDEVISDSKYRKACQRIQEEIASFDPLKIITETIDEVVGQDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAV1</accession>
    <name>A0ABR1VAV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Basic-leucine zipper (BZIP) transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663912.1">
        <property type="nucleotide sequence ID" value="XM_066818220.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051280"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052635">
        <property type="entry name" value="Sec_Metab_Biosynth_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39607:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39607">
        <property type="entry name" value="XANTHOCILLIN BIOSYNTHESIS CLUSTER TRANSCRIPTION FACTOR XANC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="211" mass="23280" checksum="529D58559046C418" modified="2025-10-08" version="1">MTSGSTKHRDSSGKKQSSSSKSKTQTADDWTEVTEPVVRRRIQNRNAQRKFPVFRRKNQRAKEKTERDALNREHAGGSYQIHDSTDLTDDEEVSGLPWGGISMRHVVARGHESESRRSGSGPDDQHQHHYNHARGGSSDDGHSGQQQFYGSSPTTMVYGDDTAAAQSYGGSFDGSSGAAAVGDDFFDDSAYYYYPDVNDDAAAMDDPFFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VB98</accession>
    <name>A0ABR1VB98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRM112 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663956.1">
        <property type="nucleotide sequence ID" value="XM_066818264.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051324"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039127">
        <property type="entry name" value="Trm112"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773:SF0">
        <property type="entry name" value="MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773">
        <property type="entry name" value="UPF0315 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158997">
        <property type="entry name" value="Trm112p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="127" mass="14043" checksum="447C58F83D0DDAB7" modified="2025-10-08" version="1">MKVLSLNFLTCAVKACKSTSGAYPLHPKDAELVEDDLEVNSDLLLNIMPRIDWPALSTTATELGFPSLPAQPPTKEELEADEKMLRDLHHLLMETQMMEGKLVCGNCGHEYAVREGIANFLLPAHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH13</accession>
    <name>A0ABR1VH13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664310.1">
        <property type="nucleotide sequence ID" value="XM_066815020.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048080"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046270618" evidence="1">
        <location>
            <begin position="20"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="82" mass="8246" checksum="02844C86A5E83597" modified="2025-10-08" version="1">MQFFTLAVAIFASASAVYAAPASGTPQDPDKGECNGTSCNFLAQNIPCSQGSTAQSGAGDKTPCDIINFGHGKAYAICPGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHV7</accession>
    <name>A0ABR1VHV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664270.1">
        <property type="nucleotide sequence ID" value="XM_066814980.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048040"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="34482" checksum="89C31BCF244DE787" modified="2025-10-08" version="1">MDLATSQSASTDAGCPVDSAASVVAGGSQGNSSSAPDDTPTPPHGKVFKTAELRTMILDHLSASDVAALRQATRVPLNKEDARKFLNPLRDLGPLHDAIVEFEKSGVRVILVGKGIKALQDSIRRPADAGTSPKTIVLGLMFEGLIPCHLSALRHFFSRLHCYCAITFDFLKNEHNYTPHTTVRVPSNSGPIPATKTVLMPVTSRVKVMLPKVFTHDTAIFYLTYTSGLFSYLADITGESNQIRMGLEVVRASSMWRSVALNSDVEDDTFTVDGVRRHPNLCHRLSLSFTHHFHYCKAPEVGGGDYAFGLGSCLAQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI25</accession>
    <name>A0ABR1VI25_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664697.1">
        <property type="nucleotide sequence ID" value="XM_066815407.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048467"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="154" mass="16452" checksum="5136D26EF5EBDCB0" modified="2025-10-08" version="1">MAVYSDFDSELTATLLVSRQVGEAMGYALLDALQDPVHVLRVDALGAAVDAVVGLRLGTANVGTDGVDKLRLGTANVGILTDGTGGVDRLGTANVGYPAANSGTLTLLFLDEVQVRVNSRGLEWEREGHARYDDREVEVVGLQWQTRDRKGQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIY4</accession>
    <name>A0ABR1VIY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665009.1">
        <property type="nucleotide sequence ID" value="XM_066815719.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048779"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="85" mass="9739" checksum="553C333E350E2449" modified="2025-10-08" version="1">MKSTPPARKETPRFSFEADSGISLFDLPLEYATDAENCGMGRDKYLGRVKDESHAISKEERQKSEKSSFNVWNKTLYLLVVQHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ58</accession>
    <name>A0ABR1VJ58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664980.1">
        <property type="nucleotide sequence ID" value="XM_066815690.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048750"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="73" mass="7662" checksum="2BC9EDA0B740F8F2" modified="2025-10-08" version="1">MACHITPLTAAIARSRRLQVGMPPLPQQSKMREQRSNGDGDGDDADDDDSHDAGNAVVASTATATIRSEDVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKB0</accession>
    <name>A0ABR1VKB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011535</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665140.1">
        <property type="nucleotide sequence ID" value="XM_066815850.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048910"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8071332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="502" mass="57592" checksum="931F8DC2BA045E3D" modified="2025-10-08" version="1">MPNLQQLGDVKPAHLGLAVIGAAAATGLLYFLYPGPKLWAASRLPYLRNWIGGHAPQTILELHHRYGEIVRVAPDELSFLRPDAWKEIMGYIPRGVLENEKDPLIFRGLNVEESVIGAPRDKHRALRSVLSHGFSASRMLDQQPIIMRYIDLLVERLREKSKTEKGEAQNMVLWYNYATFDIIGDLSFGESFGCLESSTLHPWVAVVFSWLKLNAHMVQFRRTVPWLLDIVDSVLGRMATEQVKEHMGYVRGKLTKRLNTVTDRPDFVDSMLRTDKAGLSLTRTQLEENANLFIVAGSETTATTLSFTSWLLLTHPHIMTKVTDELFATFSRDEEIDLSSVNQLKYMVAMFEESLRLFPPVPVTVPRITPPGGRQICGEQIPENTKLGVWHYPMYHHADHFAHPEEFHPERWLGEDPRFAHDRKEAFEPFSHGSRNCLGKNLAYAEMRTIMARMLFNFDMRLAEGYETWAHGMEIHNLYEKPPLFIHLTPRGEEERARLRPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKL0</accession>
    <name>A0ABR1VKL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664221.1">
        <property type="nucleotide sequence ID" value="XM_066814931.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047991"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="55"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="225" mass="24846" checksum="953F84FAB7E00F61" modified="2025-10-08" version="1">MSYKTVEQAYDSIADWYLTWVEGQRSPRESYTDKVLQNASTASNSASTPSNPPRILELGAGAGVPITRMLLDRGAQVVANDISAAQLKLAAARCPEATLVPGDMLALDFEPSSFDGVVGFYSIFHLPRKEQRTMLAQIHAWLKPGAMLAFNLATMDEEEIHGEFMGHGMFWSSYAVEDSVQMVKDVGFESVEAEELEAGDGKLEESDPDFGVKFLWITARKWSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VL35</accession>
    <name>A0ABR1VL35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Epl1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011219</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cerato-platanin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664824.1">
        <property type="nucleotide sequence ID" value="XM_066815534.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048594"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22778">
        <property type="entry name" value="DPBB_CEPL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010829">
        <property type="entry name" value="Cerato-platanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07249">
        <property type="entry name" value="Cerato-platanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045793473" description="Epl1 protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="14260" checksum="F3A8AF225B22631E" modified="2025-10-08" version="1">MQFSQIFQLIAAAATASAASVAYDTGYDDGSRSLTAVSCSDGVNGLITKYGWQTQGQIPKFPYIGAVDAVAGWNSPQCGTCWQLSYNGKTINVLAVDHAASGFNIALDAMNALTNGQATMLGRVEAQATQVAVSACGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLJ7</accession>
    <name>A0ABR1VLJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664974.1">
        <property type="nucleotide sequence ID" value="XM_066815684.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048744"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186:SF4">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="600" mass="67620" checksum="1123E5493AE06B12" modified="2025-10-08" version="1">MDPVSIALGVLPLLGGAVKVYSSVRGKCKAIGHFPREVRRLRGQFDRQYRIFVNESHLLIRAAVDDETIICRMLDDPGDTEWYSEQSETAIRNLLAKSYDAYLGVVEEINTTIEDLETGLSAYEELSSHRQKGESLKDTERRLRHHVKVAWSKDEWETNIQSLRELNADLERIRHQAFELSNPGSTNMSNRRFSLAVPREYGNFSAIQKASKALHQALATAWSREASKSVTRTLRHEVKLFTDVSVNDGVRMEVAIRCYGHTGSNSGGFLSESTWATLQVQSQSLEWLDTGLSTPPPSDDGRPKRRKVHFADDCTPRGSRPVIGAAVPASPEEVEDAPSRHRDIGHSKLCFALQPERLPAAQTRCPPCLGYIDNSNATKDGFRHSFYRNMTDAEEYCGLITMGQMLSKPLEHSVSIVQQLRLARDIAVTVLRFHSTPWLGSYLTTRDLAFVKRAPSVGFNHCLQTLHLASNFTQRDDANEDKLLDVLSMETTDDAEAEEDARLQHGVRNVTLWYLGAILLQIAYWRDMDATASDVLTVRRLSSHVFAMGPKYQELTKKCLDCDFGYGDDLSKPRLQQAVYKNIICELTDMIERLDVDPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTH0</accession>
    <name>A0ABR1VTH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665505.1">
        <property type="nucleotide sequence ID" value="XM_066813543.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046603"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="129" mass="14455" checksum="4E17B06E3A6B76F3" modified="2025-10-08" version="1">MVEWSGSIGSLKSLWHLKPLSLPLDILMGSEDELRELEDLSESDEDEDGDGDGVARKADPTGCLGELLPKPLESLHLYRGYEEVEWVRKCIQRVLSSRRLSSLNHVQLDGAEWAWPLTRLAGNPQSENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVG8</accession>
    <name>A0ABR1VVG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Abscission/NoCut checkpoint regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666173.1">
        <property type="nucleotide sequence ID" value="XM_066814211.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047271"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19817">
        <property type="entry name" value="Bbox1_ANCHR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044553">
        <property type="entry name" value="Bbox1_ANCHR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603">
        <property type="entry name" value="ABSCISSION/NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603:SF1">
        <property type="entry name" value="ABSCISSION_NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22586">
        <property type="entry name" value="ANCHR-like_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="42481" checksum="B90E914025121378" modified="2025-10-08" version="1">MADPGSSDKSLLNRLNALKPTTVSLDKSATPITATLSDDQPPSKEDALSERLKSLRGQVTSQSAQHPGNTGPGAEIPVTAPHLPSSSSSSSSGLSGAQPQPDNANLSTDIGRPAQNSAAASQGATQGTQDVETLLDTDDQTLEELLADLGSDEQWLEDMATEYANDEHQRISAMLDELGKPRAEGSRSTDSQHETDDDESDAEPMAREADHVLARAQDEVDWEKVNTPNAGCAPVRKAESKKEPALDATAPGGLNPDPFDLPTVPTNLQDPPDVPEIPHGDDFEAEIASRMAALKGLGGKDSSLPSVPSASIDDLGLPGVPTFAPEDRPVKGVYKRYGYTDEDQKSWCVVCLEDGAIRCIDCDDDIYCARCWKEMHVGLQAHYEDRGHRWEKYVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWZ8</accession>
    <name>A0ABR1VWZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666699.1">
        <property type="nucleotide sequence ID" value="XM_066814737.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047797"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="85" mass="8906" checksum="6D5AA53095463AFF" modified="2025-10-08" version="1">MAATMETGSQSAEAQHVLDEAKTQIGSKKAPKSDASLEDKTEEAKDRVDDALPKGPKKADASTGGRVQVGETGDLKELAAERHDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXA1</accession>
    <name>A0ABR1VXA1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010135</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666412.1">
        <property type="nucleotide sequence ID" value="XM_066814450.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047510"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF22">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045240730" evidence="6">
        <location>
            <begin position="21"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="64"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="309"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="326"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="434" mass="45865" checksum="43FD45BB437CCB5A" modified="2025-10-08" version="1">MSPSGINLLALLGSAMTVAASPSHAPAAANLCDLVASQLPGLVSYPGQAVYNASQDGYYTSNERDLSPSCVFRPSETAQVSQFVKLVAQNGARDKSGAYKPLFAVRGGGHTLWSGAANMDGGVTVDMRGMSSLAVSPDQKMVSLGAGGKWSDMYPQLVPYNLTIAGGRVPGIGVAGFALGGGVSFQARRHGWSCDNIYGYEVVLASGEVVYVTSDSYPDLWVALKGGSNNFGIVTRFDVAAFPSTQIWGGTVTYNYTPEVLDAQAKAFSNFMDPKNFDDAAMMGVILGFANPGGFSVSNSLFYLEPTPIPRPTRNSPPSLPRATPTPVTNGTNSLGLTAGESDVTMLDFTIAYNNPADDQMVESQLATVVAQQKKAVQDRGLLIPYIYLNYADKSQDPIGSYGGQAKDKLKAASKKYDPTGMFQKALRGGYKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXG9</accession>
    <name>A0ABR1VXG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665509.1">
        <property type="nucleotide sequence ID" value="XM_066813547.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046607"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="355" mass="38874" checksum="C7DA47C53265B915" modified="2025-10-08" version="1">MQGAIYRGLYNTASSQPFNCSSQCVWPSIARSLGFASQCEDVTAKSLSTLKHTSFSNGTHSQQVVTPGNITLNYMNSPSSFNPVIVVAAKDLTPKRFNAGTVYTPEFVRVGILRMRDTITDEHDYWFLGANVTEIFECTVRFTTYEYSDIRTAGSKLAIGNTKETGLGLGYKYDMDTRKNRWFAVFNQTQNMSPFTIGTADMGALADFYTTNRFSGSIFDGESPPASSGMGTAFLKGNIPAVFDNMAQSMTDHLRSGYSNVQPVSGKTLVSVTIVRVYWVWLSLPLGVLALAVLLLVATIWSSWGSRDQLWKSSVVAALYHNVAAGTGSGGVLYTDLQSMKHLDKLAEETSLIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZR8</accession>
    <name>A0ABR1VZR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphopantetheine adenylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666756.1">
        <property type="nucleotide sequence ID" value="XM_066814794.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047854"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695:SF46">
        <property type="entry name" value="BIFUNCTIONAL COENZYME A SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695">
        <property type="entry name" value="DEPHOSPHO-COA KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="1">
        <location>
            <begin position="213"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="406" mass="44387" checksum="0F833822951DA68B" modified="2025-10-08" version="1">MKPGELPSFLLLPPPPRPAGPLELSAAYRPTLQSVISKLKSSKGPDGSTLIIALMAPVLSGQFRRHKSLVWPEQQSILAGMYSLISVVCSQLNVPTEADGGPGSVDARVVLVDHDFTKRIPEDFKLAIEPNNTVIVNLATFIAAYHPWKQIFSTSTEAGHQQLYDYLRMYEGIQVLNQDQLVTVDGGLTLNTQSLESAQASRVTTTPHSVVCLGGTFDHLHPGHKLLLTAAILLLKVPDEGSSEPCSFVIGITGDELLKNKKYAEFVQPWEDRAMSVIEFLASMLELQRQGWKGGAAPKITKKDREITALFRSDTISVSCVQIQDAFGPTITQENMDALVVSGETRSGGAAVNAKRTELGWHPLQIFEVDVLSAEEITEEPTKTDENFASKISSTVIRKMRAESHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8A1</accession>
    <name>A0ABR1W8A1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GDPD-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007522</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667179.1">
        <property type="nucleotide sequence ID" value="XM_066811837.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044897"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14447">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051578">
        <property type="entry name" value="GDPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SPX" evidence="6">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="482"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="7">
        <location>
            <begin position="686"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="760"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="995" mass="109668" checksum="2A07C08874FB987A" modified="2025-10-08" version="1">MRFGKSFQQLIIPEYGSFYVDYVGRKALIKKLHTKGQDLDSAYQLLRDDFLRIEEFRARFLCSVHGQEKEMIDNFHLDELPRSIPVPSFRQSELHFLAEGYRGLLNILAELRWFDRVNKTAARRLFCKLERIDTQKEGKHGAQCADWFDLYAESEEKTTAAARRMSALLTGLDRARSDHAPDPHAVPLKKTPWRFGSASDRLPDIRALHHLALQGDAEKLIQLAHPDSTFGSGVVQLDQVIKYLILNHLEATAVQILERSPEYVQNMDKDCLLFCMRVTLCARSAEDVSTGPEISRREEELLEVFRRMLQLCSSSTRRSLNPDGSGAELLSFAVKHNLTRYCEMILYLGGPVMNRDWVTELMKAAKGSNLPSPFEIMLYQRQPIFIDAIKCLGEDMHGNADHDIRRILDGFLTAAVRLQNDEAFRCLIDAGCKFSSISAGERSSSGNALHIAALQGRVDYVNLLLAAIGERRETLDATEPRRGLTALAIACMHGHEGVVKALLLAGADASVNDQFGWTAKEHAAGPASNIPAMAEPVAPTLKQGEQAIIVNLGSIQARLKEDTVVVNCCSSNPATAAKEDTSYTLTVSAPQESQVGRFKTSMTFNLPLINDDLDTNPCVFLLREDATLVLTFRITARSRHGPSQEKVVGIGSAVLEGTKLAAGCPRENLVRERTAAILDCDTMDVVGLGQNIAKDKYLQIGENTIQSFLAAAKLGASFVELTRDLEAVVYHDFSFSESGTDIPIHDLTLEQFRYASKVQSPQGNPASVIGSPHRPTSGSAPRLRSRSVSRDEPGATQVQDRVKLTVDFRNKGLKPNTRGEFIHDSLVTLEELLSELPEDLGLNIEFKHPRIHETIAAGVAPVVIEINKFIDVALDKIRQSAGANRPLVLSSFTPSNAGKPPPSDLDKRAASVQAAVHFARWWGLAGIVFASEPFLLCPRLVRFVRNAGLMCGTYGPQNNEPDNVKLQADAGLDLLVTDRVGLIAKALTEHGAGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8I6</accession>
    <name>A0ABR1W8I6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667268.1">
        <property type="nucleotide sequence ID" value="XM_066811926.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044986"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="434"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="506" mass="51449" checksum="4236BD023C866A61" modified="2025-10-08" version="1">MTTMFPTTEPTSTPALTEDGCHASTDDGTVTQISVIHTSTITWTGDPADYTPPFPEDPLPCTQAPTGRFSASRCPDGQTTCDLLWLPTSALTTPVWGSVTATKQKARPTVIFWTTDKNPVVVFSSSPPPDFLGGGKPTKQNDHETVGPGTTDGFTTPVYGKVTTSTPRPPQPVVTPQPNASPKPSEVTVVIQTTQVVINGQVFKDNPESKSTTAVVGTDTFTINPTQVVGHGSTITRPFVNGVFVPSPSTTIVDGRRSSSNSHRWGKEITIGPGGIFFPSQVLPVVAEVGPPHMEVIGGTLITAIGQSVFVVGGTSLTYGPNLSPITTSIGKDTVTIGPAGVVVGGSTLGGVAANATATTYKIVGGATVTEMGTTAVVIDGVTYNVGAGATLTTTTVIAGQTLTISPQGVAVSTNTYAQPYAMTTVLSPGSAPSAGLSSPTAAADPGSFSGSGLGSSSGLGPGLSSGSDSASADEPKSKPESAGATIQLSWAHWVFTICITIGAWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8K9</accession>
    <name>A0ABR1W8K9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2415 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667305.1">
        <property type="nucleotide sequence ID" value="XM_066811963.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045023"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019417">
        <property type="entry name" value="DUF2415"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991:SF9">
        <property type="entry name" value="DUF2415 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10313">
        <property type="entry name" value="DUF2415"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2415" evidence="2">
        <location>
            <begin position="339"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="597"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="745" mass="83021" checksum="32E7117BB80DC57A" modified="2025-10-08" version="1">MLVPDEAASCWPTENLILKKGRKHYRTQISPISASSRHWQLRSVISAEGNDVLYYPTGVMSTHIMRLDTRTRETETVKVLNFHPRCMVAKNGWICCGGENGEFAIIRDIGQTEGLEAGSASVPGAEEAALANDFRSHLNPHESPLGGDPSLTQFSRDMFNMLERRLNGPTRSWTYLSKKFGTERVNCITIWQPAKPTAAPPAAPPLPRTQNYATPVAVLANNDKTITIVGLQDCEYLDELDDDPYLYIHVRKVVKRGKLGDCPEWKLLPRIRLKDQKKQSPSDCRGSFAVCFSASGRYLAVGTQYGTISVFNVAAILEAKVDPLITWFYSARFPQDNAAVRDMAFCPGPFDLLAWTEHRGRVGIADARTNFTQRQVIALDTLEGVEHLPLNDRSTIDPRLLDHRSDRNATSGGGSASHLSNLLGRTGSPRPLPNPEPSDTADRLNHPFTQEETAILEAVQNDRRRREAREAREARDQPGQHVQRGSAAWRSTVWAERVSAPSPSSSMTPPPSNLRPTDRETEQTALQTYREIAHMLRQQRETLTRILERERSTREARDPTRLVVPPSISDQQDRERRAPTPRRRGSVMQSLSQNNDSAPTASASASASRPQASSGADFGVSPSRDSPTPWGRLTSGWADLEALYNISGGDGNAGNDSTSRAETLNRARRGIPVISDVWNDDLSGFASRQNYRRLNTRDHPQYPDDTAGLAWSEDGQILWVATEDGVYEFRVNLQGRKYFPHISLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W927</accession>
    <name>A0ABR1W927_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription initiation factor IIF subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007812</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667469.1">
        <property type="nucleotide sequence ID" value="XM_066812127.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045187"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008851">
        <property type="entry name" value="TFIIF-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011">
        <property type="entry name" value="TFIIF-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="110"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="306"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="354"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="374"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="460"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="533"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="554"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="654" mass="71940" checksum="64FAA0338D5C8DDF" modified="2025-10-08" version="1">MSALPPGGPNGQGPTPPTGAAPLRKRKPVGNPLVPRQKPKPRPAGVHAPGTPMHANSKTTATPAKVAPEKMVQPRGIPTMAQIEAARVQFGGWSTPAPPGCEEFSLVLSKKGSKEGQRRHVMRLAPPQKNQKNQGLDPSNQNDFVRPVTLHRRDPRQPPPGREVKEEIVEPTSEQTEESEKLAQLKAERDAQRAHDDAMKAPKKPGTQVHYGARTEKQKKENEIRYEEALPWHLEDADGKHVWVGQYEAPLSDAKFALVMQNGVCQMVPLEKWYKFVSKRANVNALSIEEAEKVMSKKAPVSRWAMRDAQRERSEQAMVESRRIVNGGPNVKQESATFRSVSRREVQDHNELDVSGDEFQDDDETAGFEPDRDEDAKDSKDRVRREQLGANLFGDADEREVDNEEAKEKKEELERKLLGKDLKKALKRRDKQFQYDSDDSERERDPFASSSDSDTDSDDDAKKEDDKDGKDKDKEKEKEKDKSGSYKGSDTVHAKKAAVESGKKGKSLKRAGSPGVSDSSGTESTRKKKAKTGPSTASLAGSRSSTPLMVGNPSHLSGSTSDGEATGGDMSDGAGGSRAGSPNPPSATSPMEPVTGADIIEQIPPQGITIAQLLRKFDRRVGDKPGQMARNLWIKLVKENTKYDSKTKLLSRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9P2</accession>
    <name>A0ABR1W9P2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667666.1">
        <property type="nucleotide sequence ID" value="XM_066812324.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045384"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="131" mass="14840" checksum="8272433A6F44DDF2" modified="2025-10-08" version="1">MAVEDGAVLGLLLAASLEKEGVPADPAGKREYLAALLRLYQDLRKRRTETNVAGAVDTRHYYHLADGEEQRRRDADLAALPGTGWQGRCSFNWGDAEYQRSLLGFDVIADGKDKFDEWHSRRQEQTRTSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9W4</accession>
    <name>A0ABR1W9W4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667742.1">
        <property type="nucleotide sequence ID" value="XM_066812400.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045460"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="90"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="390" mass="44857" checksum="503403299E8AC246" modified="2025-10-08" version="1">MVQEQMARQSSPMLSDAEQQLCFVEDGDRIRERLVSAVKQDRDDEDEIQNLALSLSKFHKATHSLIKCLQGDIQRLKQDNADLRLGSRRFTCFSRLPTEIRTAIWELAAVETYTPKIFQANIKRVIRPDGIPEVCVRYPRHNVAQACRESRYLLHPLKPNEHSWETMSIERRALVQAGLDWCWNDIAGWQWFKSDLDGILFAATLLDSEQATGKESLNTLEALVGPLHRILLPWREDPSGNDLGLGSGIFPKFGHLQHLRSVEFVMARRKLKRSVCARWPILPFAVDVNDKVAVRETLAALGPDDAEWFRRDVRYFAEPGYVDGTGPADYWGIFHTCIREDWLLAQHEMDPPSGDGPPPVVEREVVSWDHPWVQEHLKRIPIFKRVILLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB74</accession>
    <name>A0ABR1WB74_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Defects in morphology protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008105</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EXO5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667762.1">
        <property type="nucleotide sequence ID" value="XM_066812420.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045480"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019190">
        <property type="entry name" value="EXOV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464:SF4">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09810">
        <property type="entry name" value="Exo5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="35"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="378"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="534" mass="59457" checksum="F6F4F4B8564ED809" modified="2025-10-08" version="1">MSANVPPSEDDYGSDFSLGEESLVIQLLDGLQSIPTETRAGSNPPTRQLTADKATPILPEERSLDDASFQDAPQRPATMGQARTRAAMRDNLSRAALHESWQMASMPLDGINYPDLSRALSDLQPQNAAPSNANEPADDNLRKTQSPVERFRSFPRRPLTVTDLSSGAWCELQYWYTLTTLPGGKKTRTAAMRGGTKVHQTLEDQVHTTVQVQITSKEEAFASRLWNIIQGLRTLRDTGFTRELEVWGIVNGHFVNGVIDEISYTNPNAEFGQDLGSQGQDVQQSSIKTYFESGQRQVYLTDVKTRGSATLPSGAAIRPAKVQLFLYHRLLSDMAAIKLDFSAVFNRYGLRAGVRFSDAFMAEIGSLHDEVFYDADSDMESTASQSNPSGPSSSSHGHYPDASPNLEPTVTPPPDLIRYRTLQQIVPLLQSEFQTTFPQGSKSMGDLLSVQYRHRSDGRIIGNQVFPADYDALNKYLDYNLAWWQGQREPDGVAIEETYKCRTCEFAESCQWRKDKEAEVLNRARHRVSARASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBK2</accession>
    <name>A0ABR1WBK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668364.1">
        <property type="nucleotide sequence ID" value="XM_066813022.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046082"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="36109" checksum="5CCAA48BE91F4CA8" modified="2025-10-08" version="1">MASNPTWGEKTAGSEVAQAFADQIKGRNVVITGVAPNGIGQTTASAIAAQGPAHLILASRTKEKLEQAASELRSAYPGVDIQTVILDLASQAAVRKAAAEITQLIPKLDLLINNAGAVIMTRRLTAENIELQFGANHVGHFLFTKQLMPLLEAAARDSPAGATRIVNLSSQGHRCSPVRFHDINIEGKEVPEEEKQPSYMPPAFTRVNDDGYMPIAAYGQSKTANILFTVSLQQRLKSRGIASFAVHPGAIDTNLGREHDPEMAEAISKTATYWKTLDEGAATTLVAALDPALKALNEPFLSDCQIAEPSPWAKDTECAETLWKLSEDLVGEKFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCB2</accession>
    <name>A0ABR1WCB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MACPF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668624.1">
        <property type="nucleotide sequence ID" value="XM_066813282.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046342"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="735" mass="79835" checksum="495132D54F64A363" modified="2025-10-08" version="1">MPANIDSSGGVAAGGTTTTGTTTSTPSANQYIRVFLHDGASAKEGFYITASSADLSNADLSQIRGLVARSPEQQEFTPFSSSAMLSFCSPNGATVPDSIVFAEYQEKILKAANGATASVIDVYLRKSADAPAAPSGNPSTYAPDPVALAHLKAKFDDNAFKVITGTASKYTAELEEQDWSIISENNALCYGTKLARKTMTTKKANAVETKTLLTGVERAKLPAFRLKQRPILSDKLVSTSVRDLRMYLRMPDYLVDDQSYVTMYETSNNFQASLATSSFSETDVSASVSGSAFGFSAEASASYKASTDSTATAATTKASKQIILAYNFPRVTVLLDEDSIELTRDCERELQKVVNLATLKTFLDKYGMCLFPGEFYSSRVQLGGRLFTSEEVTDSSEAATQALKKTMKVAASASFSGFGYGGSVSASQAETSGLNAANASASSRHSQTWQANGGDTLLCNDPPAWAASVAYHWNWRVTLDQAADWTYTQREDVCHIIDMIGRLPAWGHLPARVAAWTLSSIPPTPIIPQQFFLHQHGTADGRYLVVCGHRTKNLGDAARLFNQTQNSQQGVPMPGKYQTTGAVMLGPKAKVRQPDDLALQLETVEGANVDNPCYNTEYRLRSSKSKLYVSFDVHKRGGMKDRFFHRNEWKFLCASDTKGATAVFRDFSRPSDKATRTAIPDDAAVCMYLKGKEGSSFSEWVDNHSSADGEYVCLELCRERSHGMVKFVFKKKATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCP3</accession>
    <name>A0ABR1WCP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Reticulon-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007711</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Endoplasmic reticulum membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667368.1">
        <property type="nucleotide sequence ID" value="XM_066812026.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045086"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003388">
        <property type="entry name" value="Reticulon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02453">
        <property type="entry name" value="Reticulon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50845">
        <property type="entry name" value="RETICULON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Reticulon" evidence="8">
        <location>
            <begin position="74"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="275"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="311"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8079893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="324" mass="35463" checksum="E6A134F60EC12B1C" modified="2025-10-08" version="1">MADTATTNGGNTMDSLKGNAQAAYDQLSNGPVAQNVKDQSAKTTSELNNLAASRQTPLQPAATGQPLTHYHSFFSELLSWNNPRASAIAYASVVSVIFVARYLDLLRYSFKLTWMALGVTVLAEVAGKAILHQGLATQLRPRKYYTIPRETLDSMIGDVHELVNFFVIEAQRIFFAENVFASGAAAIGAFISYYLVKIVPYWGLALIATTLVFFVPLIYATNQELIDHYLKQASDVVNSQTEQIRQVASKQTAQAAEMTKQYMGDYTAKAQEMIRGRSTSPAATKKPAPAETDFPRAPKAEPEFPAVPKSDLADIKAEEEPLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDT7</accession>
    <name>A0ABR1WDT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Gamma interferon inducible lysosomal thiol reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008433</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GILT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668090.1">
        <property type="nucleotide sequence ID" value="XM_066812748.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045808"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004911">
        <property type="entry name" value="Interferon-induced_GILT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234">
        <property type="entry name" value="GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234:SF8">
        <property type="entry name" value="GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03227">
        <property type="entry name" value="GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="27892" checksum="CB7A9EAF77732D6C" modified="2025-10-08" version="1">MASHISLSSWDEKRPTRSRSARRNRPWIMIPVALLVLYTVYAIRNTAAIPAADWTLSPPTAADPKKSTAVAATPNEAHTAGALVPLEAHIMSKCPDAKDCLKEMILPAMMRVYEKVNFTLSYIGKTTENDGVECMHGPEECMGNIIELCATHLYPDPKINLGFTMCLTRDYTDIPQRELVEDCALEHGIDFEKLESCAAQDDGAFGLRMLRDSVSRSATAGVTKSCTVRLDEEIYCIRDGGGVDGLPERLRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFX7</accession>
    <name>A0ABR1WFX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribonuclease P protein subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008821</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668478.1">
        <property type="nucleotide sequence ID" value="XM_066813136.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046196"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.210">
        <property type="entry name" value="Ribonuclease P/MRP, subunit p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016848">
        <property type="entry name" value="RNase_P/MRP_Rpp29-subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036980">
        <property type="entry name" value="RNase_P/MRP_Rpp29_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002730">
        <property type="entry name" value="Rpp29/RNP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01868">
        <property type="entry name" value="RNase_P-MRP_p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027081">
        <property type="entry name" value="RNase_P/MRP_p29_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00538">
        <property type="entry name" value="POP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="Rof/RNase P subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR027081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8081003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="238" mass="26861" checksum="AB9761EBD8F4FE2C" modified="2025-10-08" version="1">MASSNPQPLTQELLARAHSPDSAARIYSDKIQHRPLYLRPNSPPPAANARAARRKTRDEKNRKRKSQKPKPLSASQRRKLGLYDVPKDGRRYAVFEPLKKLWIGYMREVLGSHLYTGGPTCAAKLCAAEYHGAEVEVTRSGCPSRVGLKGIVIKDSKFAFEIITRKNELKLIPKEGTMFRLYIPAPVQDATDTATTTPTDKNDESNNGFSFEILGDQFQYRSADRANRKFKAHYLEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL80</accession>
    <name>A0ABR1WL80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668803.1">
        <property type="nucleotide sequence ID" value="XM_066809880.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042940"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="327" mass="36427" checksum="3536DC1171AE51F3" modified="2025-10-08" version="1">MAATKTDFQAIKQTKRNKNPARSAYIYMVWAEIAVNIAIAVLGWLFLDGILKPTVPVLFFILFCWVFEIQLLMQIIINRIAVIAESQSTVRLIKYGTVIIITLINISVFIIWIPSHLDPPVNDFFVLANKYYDPVSKVLILIVDAALNWYFVKSVKERLAFLIGLMFLPNPVVFIQFHPVTYLTKLNIEMSVANLIARLARGGNNSDQFHSSSYNNTGPRTQQQRNNPQFGNEQDLALKSFTKSRIRSEPADDDSDHGVAGNGGGITPMGGIHKRLEYEVTIHQNPSPGGGGSTKPSSSSHSDSFELTKDDEMALTKYAGHPRSPGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLD2</accession>
    <name>A0ABR1WLD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MmgE/PrpD family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005584</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668822.1">
        <property type="nucleotide sequence ID" value="XM_066809899.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042959"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4100.10">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.120">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036148">
        <property type="entry name" value="MmgE/PrpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042183">
        <property type="entry name" value="MmgE/PrpD_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042188">
        <property type="entry name" value="MmgE/PrpD_sf_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005656">
        <property type="entry name" value="MmgE_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045337">
        <property type="entry name" value="MmgE_PrpD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045336">
        <property type="entry name" value="MmgE_PrpD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943:SF8">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19305">
        <property type="entry name" value="MmgE_PrpD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03972">
        <property type="entry name" value="MmgE_PrpD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103378">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MmgE/PrpD N-terminal" evidence="2">
        <location>
            <begin position="25"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="MmgE/PrpD C-terminal" evidence="3">
        <location>
            <begin position="290"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="50293" checksum="31705C2B4BD82A08" modified="2025-10-08" version="1">MADTAKTTPRDEAATSKYGANITADLCRFIVDAKYEMLAAKHIDKLKDLIVDHIGIAAGAAASADSSEPFLKAVQALHGGEGTGHSTVYTKGRTFLPQWAGFLNAAYSHSFDFDDTHAASILHPGATAIPAALAQAELSHSDGESFLLAVAVGYEITTRLGRGLNYGGYTRGFHNTATAGIFGATAAICKLRRFSASQTADALGLALSRAGGTMQFLANGAWNKRLHPGFAVHDAFVAAALAGAGVVGAAEPVEGAYGLLHAFSATSTGEGIAQGLGTEWGFAATAMKPFPACRMTHAAIEVVANVAAREQEKENETKREIVGFVVELSPGCFPIVATAIPNKLRPRTVVDAQFSIYYQVAVAWLHGAGAGWAMYEKLGDADVLALCRRVTAVVADDVRDLEARVTFRFADGSMLTEGIVYPLGEDEHPFSREQVHQKFLGVTAACYSGDTQRRILDAVERIDMINVDELLQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLQ7</accession>
    <name>A0ABR1WLQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668946.1">
        <property type="nucleotide sequence ID" value="XM_066810023.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043083"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="258" mass="30105" checksum="ACBA50FF8B35054A" modified="2025-10-08" version="1">MTTILRELKQWLKQRCKPPADTNDDKGAGPERDDEATVEGIGRFRLPTYRVKRNYYYDARDISDTPAPMMVLGILQKIYEDFNEARMILFAIAQRNTSLLNRRSRGLKLSGAARDLDKALCKAAKDMTKYVDVGYQFYDDKDHKKMSRNFANDQQVKDALETTDSTLRRVEKTIRDRIVDTLNMGMIHKEQDIDYDPLLTQTELNKKEAQDACENFHGVIKDVLRRMRRDYNLAHGIEFRESDEPREYDESSESDESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM92</accession>
    <name>A0ABR1WM92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_005916</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669154.1">
        <property type="nucleotide sequence ID" value="XM_066810231.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043291"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8084645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11086" checksum="5F027624C7118C0A" modified="2025-10-08" version="1">MSDAYERERQNNARLEELSAKVSSLRGVTVDIYDNARAQDVIDNTSDTFSSMSTQLKGSAGRLGRAAASGNKIAIFKLSAVIIGAFLVLYWLYKLFFRGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMI4</accession>
    <name>A0ABR1WMI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669242.1">
        <property type="nucleotide sequence ID" value="XM_066810319.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043379"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="179" mass="19276" checksum="0B319AF3529FE7C2" modified="2025-10-08" version="1">MVQAGPGIVHHLLAYVRVDNVDETGDGDAGLSEVCRDDALSIGAYRPWIHNETLSSNLRTTSSPTTPKEVFEHSWDSTRDSPGPKERERSGRSYKMGILSEDSPYGQLGRKHKPDLSIPSKAKRAKTAGGNIDSHGNANNGGHVETDHHCPLPKERGAQSSMALHGVAESVIVALPCYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMM4</accession>
    <name>A0ABR1WMM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669192.1">
        <property type="nucleotide sequence ID" value="XM_066810269.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043329"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="237" mass="25490" checksum="A84B9C1D350DEB12" modified="2025-10-08" version="1">MNFYSQMNLSGLKYAHLCGDTKGDRLFVFGVHTGYSGSTPLGTLPGLILHNGLSHKDPILAGACDESQWAARVYAFNLKSIILLPPVEAAPESKEMVSELMTTTTNDEGVRFEWRQFKKGSQHGADKDGFKLLSFSPNTEDSGESSTGPSTTAAAVVTAKSAGSGALAMITWAKLGSKINHPLSLEFADDTVPVLFGERWTLMVVITALRLWALRVNGRGKKSTVAIVEKIRGKSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN86</accession>
    <name>A0ABR1WN86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">NADH-ubiquinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_006247</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669485.1">
        <property type="nucleotide sequence ID" value="XM_066810562.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043622"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050837">
        <property type="entry name" value="ComplexI_51kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011537">
        <property type="entry name" value="NADH-UbQ_OxRdtase_suF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054765">
        <property type="entry name" value="SLBB_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01959">
        <property type="entry name" value="nuoF_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010120">
        <property type="entry name" value="PRK13596.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22461">
        <property type="entry name" value="SLBB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="Nqo1 FMN-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142984">
        <property type="entry name" value="Nqo1 middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="Nqo1C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding" evidence="13">
        <location>
            <begin position="391"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="528"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="539"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="573"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="595"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8084976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="614" mass="66934" checksum="D5EB12982B88733A" modified="2025-10-08" version="1">MLSRTSAPSAASAKALSRVALPTCSRIARPAASTTPSPSQSRNFATVQDGAPKRVYGGLKDQDRIFQNLYGRYPPDLKSAKKMGDWHKTKEIILKGHEWIISEVKASGLRGRGGAGFPSGLKWSFMNFKDWDKDTKPRYLVVNADEGEPGTCKDREIMRKDPHKLLEGCLVAGRAMNATAAYIYIRGEFVQEAAVLQHAINEAYADGLIGKNACGSGYDFDIYLHRGAGAYVCGEETSLIESLEGKPGKPRLKPPFPAAVGVFGCPSTVANVETIAVAPTICRRGGSWFAGFGRERNQGTKLFCISGHVNNPVTVEEEMSIPLRELIDKHCGGVRGGWDNLLAVIPGGSSTPILPKNICDEQLMDFDALKDSQSGLGTAAVIVMDKSTDVVRAISRLSHFYRHESCGQCTPCREGSKWTEQIMQRFEKGQGRDREIDMLQELTKQVEGHTICALGEAFAWPIQGLIRHFRPELEARMQKFAAENGGPALAGGWKADTRAQGKLVAPGHGIALIGLTLPALYLYTSRSASGTHPTAAAQRDIEAGYKRPDLDPAGKVRARKEETAANGGQAKHMHPEDHDPESFKPGFGRQHQRKRVDGPPDERNHQALNDSQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNF3</accession>
    <name>A0ABR1WNF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669574.1">
        <property type="nucleotide sequence ID" value="XM_066810651.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043711"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="161" mass="17516" checksum="D5753ED6434F27A5" modified="2025-10-08" version="1">MATTTAPFPLPTDDPAFYGADGTNKPNSAIDSTEGASGSSPGAIEISHGGMVAIIVVVSVVAVLGISMAVLFYVAKKREWKIRETLRRSARKVVTALTPRRTEFPKSVKESSGRTSRGRVRLDDVPPTPRLRPEDIEKGYARPGIRQSPEGRSTKDKWPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQB2</accession>
    <name>A0ABR1WQB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006478</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669716.1">
        <property type="nucleotide sequence ID" value="XM_066810793.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043853"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103:SF3">
        <property type="entry name" value="ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="326" mass="35313" checksum="ADDC80C77C519FEB" modified="2025-10-08" version="1">MSASSSTKNVIVTGAGGLVGPMLAKRLLDEGYRVIMTDIVQPTVPAGTAHPENGVCMQGDICDASFVKSLVDAAQPLHAIFVFHGIMSAGSEANYDLSMKVNVESVRHLLLHLRQTNPGVRVVYSSSQAVYGQPLPAVVTDAVTPTPEGTYGSHKLSTEIIINDMHRKGFVDAFIVRFPTLVVRPGAPSNAASSFLSGMIREPMKGETCVIPLKDRSFQSYICSPSGVIENLVRVLNMKSDALPNHVRHINFPGVAASTQALMDGLAKYGGEDKLNLLKEETDPAMERILRSWPQDFDPSTPDRLGLVRDKNPEDLVKEYIDSLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRA8</accession>
    <name>A0ABR1WRA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006853</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670091.1">
        <property type="nucleotide sequence ID" value="XM_066811168.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044228"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="191"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="228" mass="25144" checksum="2E95BDC1344CEE68" modified="2025-10-08" version="1">MAGKMVLYKLVVLGDGGVGKTALTIQLCLQHFVETYDPTIEDSYRKQVVIDGQACMLEVLDTAGQEEYTALRDQWIRDGEGFVLVYSISSRSSFSRIKRFHHQIQRVKESVNASPTYPGSPISNVAANANVPIMLVGNKSDRVTEREVSTQEGHALARELGCEFVEASAKNCINVEKAFYDVVRILRRQRQAAARPTQQDRRNPAPNGASSARTGKTGGKGKRNCVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRH0</accession>
    <name>A0ABR1WRH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669217.1">
        <property type="nucleotide sequence ID" value="XM_066810294.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043354"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="614" mass="67801" checksum="23314BDDE3334FF2" modified="2025-10-08" version="1">MMSILRSTLDDSNFSNPFTFTVSRRLAQLREKPLRHSSSPQNVSDDEWQALAKSLTWQSRAWERRALTVDSLIPHKEQHRGARDGADRRNHRPAQRTQTFPCQIIVDAASRKEGKSVQETVVWGAGEDIFARYRNTPVSASHPDVWHSLPGSENGFNPGKDDVTSISILDQETEPNVVVGRASGDLRLLSLDPSQFGRTRMTFQPSATESAQSHYTQNEIQAIDFHQTSRTLAASTKSNVLLYAADSCEGDKVDTEDGEGASTSVKPKDAFNVHMLESSEPFKTIRCMRFTEDGAIVLGLTSSSQPLRCLTLSPTGPRLDAASKMLPSARATDSYALKGWTNATVRGLLPVNTASIAGGKGNVILSSYEDGTIRLQDMRSPSPVDTIFQDNFEVMTPSGALLAYGTERFIAGNARSNTIKIFDFRWNKSYQHTASLPCSSETPYPSPRPPTLVNPPSYPERGCCDHLTGKECKWHALSKANYYRPNSTVYLPLINARSSPVYSLAKSSDTSPTLYAGLAGELVEMNLREDVGDLRKRPRAPASKPLYACRRGIASILETGDGFSLPDISKSQRVPEMRTQSNKVQVDHVPKPARNRHRLDEHLQSASDFPSKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRV0</accession>
    <name>A0ABR1WRV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669607.1">
        <property type="nucleotide sequence ID" value="XM_066810684.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043744"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="291" mass="32848" checksum="B042CC42B6A419B6" modified="2025-10-08" version="1">MAPYVAMSDTQDNGWDVGMTLPPGVSVSLDLQQQQRTMEYVGSGQLACPRAIWVYKAPYEMARKAAIEDIVQTIAVKVGATHAWIRSDVHTTGYSYDEFGNRLRLYNRHGEFIGYELVEKDPHITVNYGTSDTVVVVHGHVYVKTNRKGMLTGFMERGTREHVYNRDDRILELWKMTRDSNRPGPLGAARYCPQHPTETARCDEHYCGRTHWKTEYWTRDTWATELVAMVTSIACLVAICVMFKTFNAGNNRVPDFPGAVNLDAIILTLSTVSSSLTMYAVPAAINQVKWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWR2</accession>
    <name>A0ABR1WWR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit 9, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_002567</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670500.1">
        <property type="nucleotide sequence ID" value="XM_066806882.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039942"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18182">
        <property type="entry name" value="ATP-synt_Fo_c_ATP5G3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031">
        <property type="entry name" value="ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031:SF13">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0138">CF(0)</keyword>
    <keyword evidence="7 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="9 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="14">
        <location>
            <begin position="83"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8087606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="148" mass="15516" checksum="7A470DAFEC79A191" modified="2025-10-08" version="1">MASVRVAASRLASSMGSKVARPAMRVQVPAAAAKRTMTSNAFQTVKRQQASKIVNATTRQAFQTRRAYSSEIAQAMVEVSKNLGMGSAAIGLTGAGIGIGLVFAALLNSVARNPALRGQLFSYAILGFAFVEAIGLFDLMVALMAKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYG0</accession>
    <name>A0ABR1WYG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003119</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671052.1">
        <property type="nucleotide sequence ID" value="XM_066807434.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040494"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF1">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="33054" checksum="BE8A528CB243ED1B" modified="2025-10-08" version="1">MSSITKVALAGATGNLGPAILEQLLAAGFQVKVLMRQNSSHKFPDSVEVAPVDYDSLDSLTAALQGQDALVSTLADLALEKQLLLIEAASKAGVQRFIPSEFGSNTANEKTSKLPSYGTKIAVLEALKREADKSGAASGMTYTAVINGPFFDWGVRVGWLVNLPGREINLWDGGDRVFSTTTLSSVGKAVAGVLKRPAETRNRAVHVQDAALSGRDLARYAKKAVGGGEGDGSEQGWKENQLSVDEVVNEGYAELQKEHPDPANFAMKFITAAIFGEGYGAHFEKNDNELFGLKEMSEDEIVAMLKKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYP8</accession>
    <name>A0ABR1WYP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003231</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671164.1">
        <property type="nucleotide sequence ID" value="XM_066807546.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040606"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="PITH" evidence="4">
        <location>
            <begin position="130"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="326" mass="36034" checksum="18F9951E7F4DB154" modified="2025-10-08" version="1">MSKTIEITSSEQFSDILSKSRIVVADFYANWCGPCKQIAPVYEQLSMSLSRPNIATFVKVNTEGDKAKDVAQAYAVTHLPTFILFRDGKIAEKVKGADPQKLKSLIEKLSNDIETAGEGSSSGGGGMTWLGADLPRGYSDISDVIDVKGLELLNADDTEFSVRTLFNRPKPSSLEKSDSEQKDWVESDTDEQLLLFMPFNSSVKLHTIQITSLPPNAGEDEDEDEIPMRPKTIKLFTNRPHNLGFDEAEDIQPTQEIEIGEDDWNANGTANVGLRFVRFQNITSVILFVVDGDGSSEKVRLDRVRLIGESGEKRDLGKLEKIGDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZG5</accession>
    <name>A0ABR1WZG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Altered inheritance of mitochondria protein 24, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AIM24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671408.1">
        <property type="nucleotide sequence ID" value="XM_066807790.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040850"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959:SF2">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="383" mass="41537" checksum="B37A48D758178BC4" modified="2025-10-08" version="1">MRTASALIRRGRASQLAGQSSHICRQCRAIQISSSPTTDSPRLGGDAFGASLDTSRDVPDARFEVLGTPCSLLSVSLAASQRLYTRRGTLVAVSGKAQNAQSTLSLLSPLSRAATGVPFLYQRITSTSPITALIATKSPTTTFTVLHLDGTTDWMVAQRSALLAWTGHTLQVTPRIQYRLPLANWGSSELTGRGLAALSAPGHTYQLTLAEGEEFVAHPSNVVAYTITRNPPLPFRFKSTGITFQIPSVTNWLGNTKFFRTMRQTDWYKLMSRVLFSMRTTARRTIWGDRLFLQFKGPMTILMSSRGARISDVLTKDDVNEIADSPAGAIPAAVDLATKPKTDTTTMPKRVEPTVKVNVASVGTDGKVHIADATNAENSERPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZR2</accession>
    <name>A0ABR1WZR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003582</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671515.1">
        <property type="nucleotide sequence ID" value="XM_066807897.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040957"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058664">
        <property type="entry name" value="ARB_00930-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF97">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26335">
        <property type="entry name" value="ARB_00930_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046812307" description="Beta-lactamase-related domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="53"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-like ARB-00930-like C-terminal" evidence="3">
        <location>
            <begin position="395"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="57790" checksum="9E1F9821513A0F60" modified="2025-10-08" version="1">MLISYSKTVALASLCLSGVSSRFLGPMDPAPVDISGKDSIYHHTGPDVRNSSNGVRTVNGDSIYRVASLTKLFTVFAGLLELKPQDWNLPLDEVFPEIAGLPNDDPIRHIDWHSVTPLNLASQISGVPRDGLPFSLGEFWYTLMGLTGKPPVDPTTLGLPPISVEEANAAVPCKGYNCSVVDYIKGLQGPTFLPWQTPGYADTGFILLGQAISRLTNMTLEEYYRKAVLDPLGMAKTTATAPTEKGFPGYVVVAPLKDFALDGGITRASGGVFSTTNDLAKLGIGILNSTLLPADQTRKWMKPSTFTAHSEFAQGMGWEIYRYTHRDTGHITDMYTKLGDAGSYSSYLVLIPDYDAGFSVIQASGIAGPAARSAATQLLADIVSEAILPALQTQAAVEAKRNFAGTYTDGKNSSSLTLAYNQTASNGAGLTLVSFTSDGHDMMAQLAAQLGSMSLVLQPAIAAPRPVRQLSFQATPVVDPADEGAATGLFSKQFAVNSDWIRNNGATYGGQGFGTFIFNVSGQGEATAVTPAFLRKIYRKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZW7</accession>
    <name>A0ABR1WZW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003684</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671617.1">
        <property type="nucleotide sequence ID" value="XM_066807999.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041059"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06867">
        <property type="entry name" value="PX_SNX41_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044106">
        <property type="entry name" value="PX_Snx41/Atg20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051079">
        <property type="entry name" value="Sorting_Nexin_Autophagy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46979">
        <property type="entry name" value="SORTING NEXIN-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46979:SF2">
        <property type="entry name" value="SORTING NEXIN-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="10">
        <location>
            <begin position="89"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="230"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="436"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="623" mass="69591" checksum="6B99C1AAB3747693" modified="2025-10-08" version="1">MWNDEEDNNPYGTSFDRRDSVTSSSVNAASPSSRDSDLEWIFADNPRFAEPQTPSTTSEDAPPPPRSYGQDVPRRKTGGYSSRIEQIIYENPELPIMITDAGKSAESGGRYIVYTIRTGDLEVRRRYSEFASLRDALTRLHPTLIIPPIPEKHTMADYAANPTNAKQDQQIIDLRKRMLAVFLNRCRKMDDVLSDGVWWKFLDPNVSWNEVLQTHPVASIPKSILKAPPLDTANPSDGHSHLPIPATSSKLKGTSAAGPPSTFDSPSSTTGPQILQRFPPDTHNLSEQELDPYFNSFEASIKDMEHLLMGSMEKVNRRTLSHLTALSGDMSDLGAKYNAFALSEQDSSLAAAIERVGQAADSSYIATEELAGSLGASFAEPMRENAQFAGVIRNVLRYRTLKRVQQEMTNDELIKKRMLLDQLERSEAEARRIEQYLSSSQQIGSAQQQHQPPRRSSSMKENSTSQHHRESSGEDTASIDSDFPPTHGDFSSAPSARVGAPERSPPTHKKMPSSNSITNKIFGPIRHAVQGVVDVDPERTRRDTMGKTHESIEHLEQAQVVAAQDVKDASGSILKDLKRFQGEKEEDLRRYMLAYAKSQIEWARKNKEAWEEARAEIQKIEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZX5</accession>
    <name>A0ABR1WZX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003636</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671569.1">
        <property type="nucleotide sequence ID" value="XM_066807951.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041011"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42032">
        <property type="entry name" value="YALI0E30679P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42032:SF1">
        <property type="entry name" value="YALI0E30679P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="191"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="467"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
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            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="495" mass="54623" checksum="D3F3C0B4DF4BE09D" modified="2025-10-08" version="1">MADDNSGPMPAAAHSAGRPPHSPDSAPPGYGMRRAVTVDESAHVRRRPTLNSPTTDPFSDIRRRSSNFSDFSLNDARHSFGHNVENVWTADKEKKQSAERARYAMIPLVLALLPAVGGILFQNGSAFLTDVILLGLAAIFLHWSVTQPWDWYHAAQEIRLLKDAAMAEYVFESDTEIELSVTDSATTALEHVPEEDEKDGETAEDQPPDDQSADPARMQWKSRRESASRELYTHEVLALTGCFVFPVLGALLLHAIRCQLTRGSEGLVSDYNLCIFLIAAEVRPVSHLIKLLQNRTLRMQRLVGANPYLAKTLRDQQIENLYGRLDELESRAAAAAAAAAEVSSATSVHSDTSDNNRAVEAMVERCMRDNTQPELDALNRAVRRYEKKLALLANATDRRVEYLEHKMNDAIALAAVAAKHSASQADLGHWLAERMVAMLAFPLQTAIAVCGAPFRAWSTLFGRKGRSAVEKSHRTGRRPGSAKVNGDRGSSRPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X040</accession>
    <name>A0ABR1X040_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">feruloyl esterase</fullName>
            <ecNumber evidence="2">3.1.1.73</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003713</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.73" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671646.1">
        <property type="nucleotide sequence ID" value="XM_066808028.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041088"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043595">
        <property type="entry name" value="FaeB/C/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050:SF2">
        <property type="entry name" value="FERULOYL ESTERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0858">Xylan degradation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8088752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="339" mass="36483" checksum="759EC45F512D26F5" modified="2025-10-08" version="1">MQILPATKRHLVFGGPGDRQPHLYVLAPTVVQPQQTQPLILSFHGGGVNSDRQADQDFFADAAFNPDHIVVYPQGLVLDACNVAPPTTVWQGLRLIPRYWDDVAFVVALLDHLERELLCVDPARVYAAGKSMGGGLADILACDERSSGRVAAIAPVAGAFWANVDPRLCAGPAAERVPVPACPGKRACPVPVIAFHGRNDTTAPFGGGAINGLDCVPPVQRWVEEWTVRDGLDPASPALEKLPSGDNATVYRYGKAGGGEENAEKGDGLVTFVMAGDHVNHDWPTTVDYGGTSRVLEPGQGPANFNGTSMMMDFFRKYKTPYVKTAYTFALLLRVLTRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0M5</accession>
    <name>A0ABR1X0M5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Adipor-like receptor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003855</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671788.1">
        <property type="nucleotide sequence ID" value="XM_066808170.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041230"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF97">
        <property type="entry name" value="ADIPOR-LIKE RECEPTOR IZH3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="504" mass="56240" checksum="0281BC4C52412F4C" modified="2025-10-08" version="1">MACTSTFALGPSEEPTEATSSALPSGETAPRQRRRHSFFIPRRKSIVNHIMDGEEGLLLKVDLFLSELERRLEYLESFGEGTFDGSISRAYATLQTVRARCSQVSEEVIGAGRKRLQVMVETLDARYHEALVAAESVNEKAKVGIELMDTMLTEYEARALKFRDKGLANAAGAAGSLMDEGRRVVDEGLERARGVVDEGIERAKRAAESVEEHVQHAVARARHGLLKYEELPVPWRVNPHILKGYRFSETKLGCVRSMFNFSNESVNIWTHALGLILVLAIAFYFYPTSPNFSLSSNTDVFIAALFFFAACKCLVCSTIWHTMNCVADQTLLKRFACVDYTGIALLIAASIMTTEYTAFYCEPISRWTYIVATGALGILGVVMPWHPFFNRSDMAWLRVGFFVGLGATGFLPVFQIILTRGPEWAWEFYTGSNLVKSLCVYVLGACIYASKVPERWCPGAFDYFGNAHNLWHVAVLGGILYHYVAMQDFFAGAFRRAQEGCPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0Y0</accession>
    <name>A0ABR1X0Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004029</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671962.1">
        <property type="nucleotide sequence ID" value="XM_066808344.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041404"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF237">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ATNE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="122"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="17587" checksum="96CDB9C30F15C41F" modified="2025-10-08" version="1">MAPPASVQPSRELVCDGMAVKRQYIPASVHARTMLYYLSYIEEVYPDPFKFNPGRWIVNEQGLIGSPAQDIALAERGFCSFFAESRGCPGKNQARLEMSITMAKIIFGFEMMLGPTIHLGASDPEGKAGRGEASRYQTDDTYGSMGDGPMTHLKRRKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0Y9</accession>
    <name>A0ABR1X0Y9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671948.1">
        <property type="nucleotide sequence ID" value="XM_066808330.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041390"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013887">
        <property type="entry name" value="UPF0592"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37988">
        <property type="entry name" value="UPF0592 MEMBRANE PROTEIN C7D4.03C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37988:SF1">
        <property type="entry name" value="UPF0592 MEMBRANE PROTEIN C7D4.03C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08578">
        <property type="entry name" value="DUF1765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="928"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1139"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1056"/>
            <end position="1089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1160" mass="128158" checksum="816EFFD6AB6CEF9A" modified="2025-10-08" version="1">MVPERSRLSHSNLDVTSRKPSPSTTTKHLSPLPAFDIPSFDLPDFDFDPNFSIPAPDRTASTDAKHTSLPASEPDKMGRARGKSLLTRRQSWMPGSKSPSEHDLPQEQEKEPSRPPQSPLEPHHVEQKAADKSRSVSGSFASLAKRSTSWISTSRSPSPSPRKEARDYVSHKPQGREPSPNNEPVAQSPKYLRKRAPSGMDREANKSSDSLGKLGNYLSKMKQRPQSLLVRGMSVNDGDSTASSIASSATNTRPSNAASENSNTTVPDEVQRPPTTQQPRDPLWSAFKSLDAEYGRFQAKSVHMKVGVVRNTLLPFLRKYALHPSNNTLHFEELEPRASILNKWWVGLLELLDGKANQSVAGVDRPIVLEVTTILMMRPEWRQCIPQFSPLAHRSPREPAGRKGRAHSDESGNQSRSSTADTDFLAESAEHNVRTMFVTNLVTQMGIVVDKLSQRHAPLSLVNFAGRACAYAFFFAPGVAEVLVRLWALTPDVLRRVADEFRLPRRSKGESDDLTALFPPSLENLGWSSVRAMVQSLRQAAQLPLVTAKIAWHGQWVSRWRGHDTDLFFLFCKYYYILAEEFMPPNLPLEEKGLAPAFVLVNAQLLATLDSTIHRQAGLEASMGLPLSEGADASAMALSMNLNNNINRGMNENRLIALLKDFLSTSSMAFPGARHSFAEAFMALMKAAAKRTCQFDHNACFTLCDFLEESLAAYRGFLGMGRMSLDYVDWPFWLEVCQKILDSNHTMSEVRVLSLVFSIWDLATSEQARKEAICQGWLLTEDTFNKLFNNWCPMVRAYYMRLLCWRICRNDGGANDSDIRMFRLAATRLGTVWSHYQWLRDVAEGQRSCGPSTAPATPAPGKRFMIIRTEAPGAQPGLMVGFDSFSTSFNPLESTSTAPAPPEFVSPPNTDTAAYKKKWNLLGRVLHLSNGSNPEDAEPSVRDGTMAHKPAPPPKGASNPVTPPASDTDSIGSSPIYESLRYVFRFTLSWNGPNMMPPAERILTQPRLPLPAQSQLGFSDMGNSSHALPAGRPAPTRAVSGSVQSGLIEAAKNAEVSETSASPRSSATMDRRGSQSPSMERISSNQSSLYQDRITTPTAEAFVHGTKPSRHLERGAKYSGRALAEWSLVVAECNSFIDRRRDEGVPDLSEVEVPSLGMPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1B1</accession>
    <name>A0ABR1X1B1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OBG-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672121.1">
        <property type="nucleotide sequence ID" value="XM_066808503.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041563"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04938">
        <property type="entry name" value="TGS_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01899">
        <property type="entry name" value="Ygr210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013646">
        <property type="entry name" value="YGR210-like_G4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF1">
        <property type="entry name" value="OBG-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08438">
        <property type="entry name" value="YGR210-like_G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="2">
        <location>
            <begin position="5"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="414" mass="45126" checksum="A9127D50CB0E491D" modified="2025-10-08" version="1">MARDPLIALVGKPSAGKSTTLNSLTDATSKVGGFTTIDPQRAIGYLQIDCACKRFNVSDKCKPNYGGCVDGRRSVPIELLDVAGLVPGAHEGKGLGNKFLDDLRHADALVHVVDASGRTNAEGENTRGYDPSQDVAWLRSEIVAWIKGNLYQRWGSIKRRHVAVKAAAVDTLQAQFSGYGATTQLVARTLDKLALKEPLEHWSEETVDRVVAAFTDEKFPTVIALNKIDDPDAYTNLMKITKMYKNSLVVPCSARAELFLRKMAKQGYVQYVEGSDSVWTRQDLIDDGDPEGGGLKEMDEKNKEIIDEYKDMILYRYNSTGVVDVLSAAAKLLGLVPIFPVRSTATFSSGNDARAVFRDCVLVKRNSTVGEVAKKVMGDVTIAYVEGVGGTRVSEDDIVSVGKHDVLSFKVGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1D2</accession>
    <name>A0ABR1X1D2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672083.1">
        <property type="nucleotide sequence ID" value="XM_066808465.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041525"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="176" mass="19414" checksum="423C1D1ACD955A81" modified="2025-10-08" version="1">MDKVDMLLGRPRSPESSPRQDNTRLFPRRAGSVRRGRGLMLAVGNHISYLPPVCNRESCWNGCRWSRESAFAACPRPGRWVLIRSAASDEVKIVIEQPSRGTLCSLGCLTAADSVPFPPHGCGKPTGTFLSPASSLSTTESVPRCLRSVNQAILVLMHAQTWDLSSYHHLQPRYVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1Q2</accession>
    <name>A0ABR1X1Q2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">KRIT1 ARM-repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004309</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672242.1">
        <property type="nucleotide sequence ID" value="XM_066808624.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041684"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053210">
        <property type="entry name" value="ANKRD12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056485">
        <property type="entry name" value="ARM_KRIT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24149:SF14">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24149">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24521">
        <property type="entry name" value="Ank_KRIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="371"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="404"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="KRIT1 ARM-repeats" evidence="3">
        <location>
            <begin position="511"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="653"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="493"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="659"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="670"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="707" mass="77250" checksum="DEB9DD46EF268411" modified="2025-10-08" version="1">MDEPKHQAVESSAKPVATSPKRPDTLKPPPAAPPTATATTATITSKSPTKDPDPNPQEEDGTSDAETIVLHGLSPTKPPRKVITIKHEEKSEGEIDDTPLSPKKAVKDGKDGKDSKEGKVRVRGDDVGDEKPPLKKKRPLDKDGQHRTKDAASSGLSSVPASPPPHPDRQHNTQRRRRSSGSESEHTRPRSPRLIKDKAKSVDRQLKRKAPKAESDDEDGSHKARRPRISDQGTKPPSARALQEKHTSRARSNSPHSRLHRRSTSTQLPAQSSNGVLKKRRPAPLMSTDYQSDDSSASGSPHPRSSRLKSIATPLTGDSTASPAKMHGVHKKHLDAHGQTLFAKACAKGEYDVAKMRLQERPEDLNFSDHAGNTPLQVACLNGHEDVVKLLIEAGCNLDCRNDDKDTPLLDAVENGHLAVVKLLLAAGVNPRRPNAEGQEPLEKIPDDVDNADEIRAALMDARTKMGELRRTSEDHQLQDQDTSSHGADSPRRSPAASASGAAAAASRRGGTVRSTKTSNHLLYMSLDDKTLRQAAARGDSETVTRILQVKESCDDAEALVAAARGGHNFVMELLLALGGANPDPAPVKTLPTEHSTPMLAAIGGENTKVIQLLLNQSLFDPTRRFKGETYHEIARRREGPMWKEEEHMLKDAYDDYKKSHRVSKAKSPSRREQDHDNKRAARPDSNQDSSVRPQKRRPSSPPQRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X218</accession>
    <name>A0ABR1X218_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S acidic ribosomal protein P0</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004430</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672363.1">
        <property type="nucleotide sequence ID" value="XM_066808745.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041805"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="4">
        <location>
            <begin position="85"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="185" mass="20121" checksum="576A406522DF45A8" modified="2025-10-08" version="1">MVGNKSEYFGKLKTLLEEYNSVFLVSVDNVSSQQMHEVRQPSLPTPPEYERLLPHIRGNIGFVFTNGDLKDIRDKILANKVAAPARAGAVAPADVYIPAGNTGMEPGKTSFFQALGVPTKIARGTIEITSDLKLVEAGSKVGASEATLLNMLNISPFTYGLGVVQVYDQGNTFPLRFWMLVRSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X248</accession>
    <name>A0ABR1X248_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Ornithine aminotransferase</fullName>
            <ecNumber evidence="4 9">2.6.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004420</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:13877"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="EC" id="2.6.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="4 9"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672353.1">
        <property type="nucleotide sequence ID" value="XM_066808735.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041795"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="450" mass="48717" checksum="0C2E46F98FDE51B0" modified="2025-10-08" version="1">MAPHANGSGTNGSAASSRYHASSTKSAIDAEHKFAAHNYHPLPVVFAKASGVDVWDPEGKHYIDFLSAYSAVNQGHCHPELVKALTEQAGRLTLSSRAFHNDVFPKWAEKVQQMFGYDMVLPMNTGAEAVETAIKIARKWAYKVKGVPQDKALVFGVEENFHGRTMTAVTLSTDPESKDNYGPYIPNVGAICPSTGKAIRYNNVQDLEEALEAHGKETAAFIVEPIQGEAGVVVPDAHYLSKVQELCKKHNVLLICDEIQTGIGRTGRMLCSEWAGIKPDMVTLGKAISGGMYPVSCVLSSKDIMLVVEAGTHGSTYGGNPLGCAVSIRALEIMEEEQLTEKAEKLGNVFRESLAAFKSPVVKTIRGKGLLNAVVIDESKTNGHSAWDLCLLLKDKGLLAKPTHGNIIRFAPPLVISETQLQKAIDIIGEALQELPKMTKHEEVHVGLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2N9</accession>
    <name>A0ABR1X2N9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dCMP deaminase</fullName>
            <ecNumber evidence="4">3.5.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">dCMP deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004640</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672573.1">
        <property type="nucleotide sequence ID" value="XM_066808955.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042015"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086:SF18">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="7">
        <location>
            <begin position="217"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="333"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="348"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00041763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="362" mass="38842" checksum="E791B8557DBC2BD9" modified="2025-10-08" version="1">MLLGVCGSKCAGKSTVAQYLVEHHGFQRLHLSVPRVSNGTAPASEPAEESVSSDSLQNDGFANQLAVRGKASPPAHSFTSATDLLDFVTKYWRSRWVTTDIHDEAVLDVLSRRPFFILVSVDAPIVIRWRRYQARNSNSSHSSSSSSPASSSSPPTASSLEEFIAESDDHLYSGASGVLPLISRATVRLLNTSSSLAHLYATLGKLDLTNPERLRPSWDNYFMSLASLAAQRSNCMKRAVGCVLVGRERRVISTGYNGTPRGIRNCGEGGCARCNAGMGSGAALATCLCLHAEENALLEAGRERIRDGSVLYCNTCPLPHLLHQDRPGGHQRGCLQSGLQHGRGRPPRSSGALVLSSGSSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X317</accession>
    <name>A0ABR1X317_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine(37)-N1)-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA methyltransferase 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TRM5</name>
        <name evidence="11" type="ORF">PG997_004771</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion matrix</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="9">Predominantly in the mitochondria and in the nucleus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRM5 / TYW2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672704.1">
        <property type="nucleotide sequence ID" value="XM_066809086.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042146"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03152">
        <property type="entry name" value="TRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025792">
        <property type="entry name" value="tRNA_Gua_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF36">
        <property type="entry name" value="TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="10">
        <location>
            <begin position="123"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="262"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="290"/>
            <end position="291"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="456" mass="50402" checksum="CA5FA84EE8A466A8" modified="2025-10-08" version="1">MAATRSKEEMNVFRPSVARAVAGVLDRSLFAKTVPLAAAIISENKLISRYRRDLEKSKEILSADRISAIAPHPDQTLASQGKKCLLLNPAVKPAAPETWGTVLKDGVDKSELEVIPYNLNLDYEYFSALDVLSVVLPPELHDEIPSGFNVAGHLIGEIIVDKNPHIRTVINKVDNVGSESEFRTFAYEVLAGPDDLDVEVRENDCSFHFDYSKVYWNSKLEGEHTRLIRSFQPGEVVCDVMAGIGPFAVPAGKRGVFVWANDMNPESYRYLQEAIQRNKVGMYVRPFNEDGRTFIHNAADSVYAASQAGDHALIQTKVRRHLRGAAGTADATPPPQKIPVPPTISHFVMNLPAMAYTFVHHFRGIYAGHEGLFAPNTETKLPLVHVHCFALKSDDEVPLLDICERLTSELGVKMVPGDAEKPGEVSIYNVRDVAPAKRMWCASFRLPSETAFAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X318</accession>
    <name>A0ABR1X318_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protoplast regeneration and killer toxin resistance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672696.1">
        <property type="nucleotide sequence ID" value="XM_066809078.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042138"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATOR SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="237"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="663"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="135"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="680"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="693" mass="74962" checksum="499CB7BECEEDCD35" modified="2025-10-08" version="1" fragment="single">PAAESAVSDPIYTTEPHGSPDRSPERHKWGGTEESDSKPSPLAIPDAPKMRAAPVSPVRVSFHPDNWAQPSNVSIEGSQAQSMQPAALEHAGEGRLSDSDATGTLRASSDTSPQESMGENEANGDGLRRSRDTDTSSGTQQMASTESSVATNASSVSQDVGDSQLLSEGTSPEESVVDDSASVKQPVPQLQYHHQQLMASSRVASAPLDVDPRPSSTVNLNEQGMAINRHLTPTSAAFQRRSSMPRPQSTYSVYSDLSPRGRSPGLTRKSPDARPTSYAELLNVPYPQPAPAPITIDNSQLRTNVGSNASLLSTQKTLEMYRQNVKKTNDPSIQYSFAIFLVASAQEQGVSFGETPKGKFPRREPQLVREAKSILTRLANGGYPFAQYYLADGYASGLFNKGKEDYNAAFPLFILAAKHGHAESAYRAGLCYEFGWGCRKDPAKAIQYLRTAASKTHPGAMTRLGKACLAGDFGETRYREGIKWLKRATESSDTIYNAAPYQLGTLYETGYGEDVFKDESYAAELFTQAAELGHAEASFRMGDAYEHGKLNCPRDPALSVHFYTGAAEGGHAGAMMGLCAWYLVGADPILEKDEEEAYEWARRSADLGFVKAQYTVGYFTEMGIGCRRDILEANVWYVKAADAGDERATLRLAAIRAAVSGNGAPMEVAPPKSAKMRKNPPKDGKDDKDCSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X331</accession>
    <name>A0ABR1X331_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672719.1">
        <property type="nucleotide sequence ID" value="XM_066809101.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042161"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="35319" checksum="B7884D0010BB4F47" modified="2025-10-08" version="1">MDDIPAGDHFKEQATIDSLPVQVDIAEKVPVDQEPQDTTELQPTQVEAVEKEPTGQHLQEQTTVESQLVVGGSSVEEAASETVVPIKKSKKKKNKKSQSTIEPTSDSLVPSLNEPLQDVTVADAPSQPQPDETSRPAALPSADAPKPDDARQAESVPLGESVPVTSSATRQSTPELDYLPSAPGVHLRRKDSVDAPREEIYFPSALSMLPAVNALQGHRYPAQAETKSSEQQGPPSELEEGKNMPEEPHGWAEDSDRRGEPGELGTEALRTTPAPVHVTTGFDGPDLSQDKSTKPTVAEDVEELHPRPEPRPIFSAVRRSSSGALVGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3C9</accession>
    <name>A0ABR1X3C9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004879</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672812.1">
        <property type="nucleotide sequence ID" value="XM_066809194.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042254"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="2">
        <location>
            <begin position="84"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="37327" checksum="12AE44BA4460DADC" modified="2025-10-08" version="1">MAPPTTDNNNNLAENLQVQFRSVPVTAENHDAKRALIHAMDRVMAVPGERLLAQAGLLPPVDDGDGVVPKDKQEGRDEPFALFDNACGMGLITGLLQKQASPAVLRESRFVCADLNANLVDIIKWRAETDGWKGAVETAVVDAQDTGLPSTSFSHVVINFAMHIIPKPDVALREAYRLLRPNGTLAFTVWTHDNTGWIPDMRSAFAALPFADNAAAAAAPLMPDRVPMAVHGLNQWIDPAGIRAKLASSSLHTFNDIHIETLEHTSHVYSAGYFVESFDMVRKWMMQSYWSEESRQTAAGMGEARMDEIMINHLQQKHGGKSWDIRWKSILVTCHKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4M0</accession>
    <name>A0ABR1X4M0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673231.1">
        <property type="nucleotide sequence ID" value="XM_066809613.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042673"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="110" mass="12510" checksum="C235FC613E404F8B" modified="2025-10-08" version="1">MAARFPQDHFVKAESASQDGTEEPPPWLWLLWEFNLRHEGDIPTNSGILFALPTRPMVWIAEERLRAAGTSPYLSSEQITDASMEKYRNDRGLTAHYIIKALRSSYGNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4X8</accession>
    <name>A0ABR1X4X8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Endonuclease/exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_005434</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">PML body</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673367.1">
        <property type="nucleotide sequence ID" value="XM_066809749.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042809"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09080">
        <property type="entry name" value="TDP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051547">
        <property type="entry name" value="TDP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15822">
        <property type="entry name" value="TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15822:SF4">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="12">
        <location>
            <begin position="98"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="18"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8090473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="368" mass="41170" checksum="679000B8DC35D409" modified="2025-10-08" version="1">MSKLTSHIQKSIRRLLQAAKPGQQKTAAATGNSSFKVMSQTEPATSDPWAPAPQPHYAFNHSTQEWEPQTATDQQHEHRHGENDDAQHQEITNLALFSWNIDFNLPFAKARMDAALETLRDECVKSDLEAIAEKGWVRDRFYLTDLPTSAARNWRGSSYGTTTLVDCRLSLVKLFRVHYEQTRMQRDALFADVLVPPQGSETGGEDGNKGKIVRLCNTHLESLALTPPFRLPQMEVVARYLKDKDIGAGIVAGDFNAIQDFDRTLHAVNRLRDAYLEMGGREDAKEGYTWGQQASTAARERFGCSRMDKVYYTPGSNGDEVRGGVELPAAEEEARKGLVGLGYERPWVTDHLGIMAEFEVVAQRDEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X554</accession>
    <name>A0ABR1X554_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ergosterol biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_005445</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673378.1">
        <property type="nucleotide sequence ID" value="XM_066809760.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042820"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005352">
        <property type="entry name" value="Erg28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451:SF19">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03694">
        <property type="entry name" value="Erg28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8090484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15258" checksum="7B9DA24D6FABE2A6" modified="2025-10-08" version="1">MASSLLPQSPGFLPYYLIYSGMSAVLHSVACYRMEPAKSLKAFSGPARPPPTGLLARVYATKNLYTSLIRLYAAYHVANPQLYDLATCTFAGVLWLYVTELAAYKTVRMREATFPFVTAGVGLVWMVMQREWYRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7M3</accession>
    <name>A0ABR1X7M3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673494.1">
        <property type="nucleotide sequence ID" value="XM_066806198.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039258"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="35465" checksum="5CEA4200F1306D74" modified="2025-10-08" version="1">MRHDISNNTNRPGQRRRRHHPSTASTAVRCPHSDGTVPVCWDCVEAGHPGGTRNNAAAAAALVSPLSEKKRKRSKASIFSKLSGTGSSTHSTLQVHPPEPGKEVIVADYRHLSQPGLEVLAGPRVVDPASKAYYKNNTNKTKKRTDAETWDAESTTGRSESKEGRILGMSKKRFWFTALLIGLLVVVITVGVVVGVQQSGKFAKNTSAQSNGESGTTPTTSGGPSSSPSATSSPGGTGPITCPSANNSTYTLPDNGNIKFKIGCGFSRDGGDLQSVTADTFLQCMEECVKRTGCAGVSWINDGDAGSANNYCYTKLSMDGKTRTNPFAQSAEIVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7X6</accession>
    <name>A0ABR1X7X6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673500.1">
        <property type="nucleotide sequence ID" value="XM_066806204.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039264"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="147" mass="16646" checksum="480D7D60DF80F3B0" modified="2025-10-08" version="1">MIKSIQILLDEELSRIAEEVLSLRSQREAIFSYYHSPDVETPRCGQVQFCIKHEGNTPFIFELRHSQKEETIDDKVNKYGSYGRELSALLSLGIKYASLEKPRAPDHMHSASVTLLTVDPDDQSQEPANAVILNCPTQSTILRDERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8C1</accession>
    <name>A0ABR1X8C1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673691.1">
        <property type="nucleotide sequence ID" value="XM_066806395.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039455"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046184504" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="18376" checksum="B7A19BAFA539B9B1" modified="2025-10-08" version="1">MAKLSLLGFFLCALMAMLARGNEDAWSSKCYDGAAIINNRVLMAYCKTTIPMGPPWVCSKMNLNFCYGFADAPGLFAKENGFYGDSCGVCDLEADGHTMACWCRPSTTPVYSRYTVDTDYCLTVNPNGFLHCFMQTAAPCTESEEATFLNMTLGSHVRDTTMSLPLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8T7</accession>
    <name>A0ABR1X8T7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673762.1">
        <property type="nucleotide sequence ID" value="XM_066806466.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039526"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF2">
        <property type="entry name" value="SET-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="2"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="310" mass="34982" checksum="082824423C9DE9CC" modified="2025-10-08" version="1">MTPITINDFLILRASNTSAKGAGLFAKRDLEPGHRCDSLPQIGSGRPSVRDSLSGERRIQMARLPAGPGDKFQVDASQVPLSTTLFRNDGRLMNTVKYNELRIATAKYPMVGFYTSVAGHSCTPNSYLCYNELTDSLDLHLVRHVKEGEEITVSYFQDDYAVPKSVRAQRLQKWNFTCPCVCCTTHSEMSDTRRTSIKRLFSDYDQINIARIMKDVELGRQRSSGRGTRAEVDTEVWDQLDNLRQIIRHMKDEGLYGLAMKWVLADYAVHLQEAGDLQARRATMRESLQIPEMCLGVFHPDTRALAQCVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9L8</accession>
    <name>A0ABR1X9L8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000039</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674127.1">
        <property type="nucleotide sequence ID" value="XM_066804354.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037414"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053007">
        <property type="entry name" value="CYP450_monoxygenase_sec-met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047482576" evidence="6">
        <location>
            <begin position="19"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="497" mass="55814" checksum="11F8E09F42E79F93" modified="2025-10-08" version="1">MIAYLLSALAITWASLVALDRFLSIPHQLNEPPRILPKVPFIGHIIGMIQHGSNYYEILTKRSGLPIYTIYLPGSKIYVVTSPNLVTAIDRRSKTISFGPYVLSVDLLAEDLLEDDGPVGLRPETLKVMHESLAPGDDLQAITRVMLRRVAEHLEALHCREDAVVAGLFDWTRKFVTRASTDAIYGPSNNPFHKEDVYNALWTIDREFVLLGLNILPNILSPKGARGRRVFFEAMSKYYAAGHHKTASPLVQARHQVESKYGMPQKDMEHFNLSVSYGLLVNTVPSSAWVLYHVYSQPSLLSDVRQTIDSLVRIEGSTDVRVNLPDVIKAYPLLESLVQEVLRLHSTNASGRVVLRDTLIGDKYLLRKDAILLILSKGMHSNTEVWGPTASTFDPTRFLKQRAGRDPHRVPASAYRAWGSGASVCPGRYFATNEILSILIIMVLRYNVSPVRGEWKMPATKSHITTSILTPVTDIDVHIRPRKETSGIQWTFTWETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAG2</accession>
    <name>A0ABR1XAG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674380.1">
        <property type="nucleotide sequence ID" value="XM_066804607.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037667"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004177">
        <property type="entry name" value="DDHD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058055">
        <property type="entry name" value="PA-PLA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509">
        <property type="entry name" value="PA-PL1 PHOSPHOLIPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509:SF6">
        <property type="entry name" value="PHOSPHOLIPASE C1020.13C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02862">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01127">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51043">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDHD" evidence="2">
        <location>
            <begin position="389"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="621" mass="68458" checksum="EF2702C60B9F0568" modified="2025-10-08" version="1">MPVDIAVANQLEAGYRELKPHTETWRDELRCAVEVGPDGEEKVSHRLWPKEMDESAKSKVPPEPIIPSNPFCAARCFRGEAAAEGNLLPSSNEDNYIQDQSHRKYDQYHVIYKDKDSAFLLKPSLKPSAYYGRRPVAKIAKGITIGIPVVRGFDAAAWAKLHEKKRSQVAHAPNPSSAATASQESTGPSACPGCKTEKERGQVTDLVLVAHGIGQKLAEKVESYHFTHAINAFRRAVNLELGSDAVRSVLREGQNGIMVLPVNWRQKLSFEEGGPMKEDDKADYMPEGFGLKDIEPPTIPAVRSMISDIMFDIPFYMSHHKPKMIAALVGEANRVYRLWCRNNPGFSERGRVHIIGHSLGSAMALEILSWQPTVTPPLNLSTEMSLQHFEFDTKNLFLVGSPSAFFLLLERGALIPRRGRRKPGADPADIVSGDVVGESGQFGCLAVDNVYNVLAREDPVAYFLNGTIDPKYAASLKTAYVPSATTTLFQSVGNAVRSFVPGAGPSQAAIANNPALAKPPPALRLPSQLELEVHDFTREEVAEKKAFLLNDNGQIDYFLRSGGGPLELQYLNMLSAHSSYWANHDFIRMFCMEIGRKPGKANTLPAMRAMKAKRRALPDMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAL8</accession>
    <name>A0ABR1XAL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Pyruvate carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000376</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674464.1">
        <property type="nucleotide sequence ID" value="XM_066804691.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037751"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45007">
        <property type="entry name" value="CARBOXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G07570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45007:SF1">
        <property type="entry name" value="CARBOXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G07570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="9">
        <location>
            <begin position="1"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="117"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="558"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8093691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="653" mass="70442" checksum="750C70B8AC1D9682" modified="2025-10-08" version="1">MSSPGYPPRRRIKRLLVANRALPQIEPFALVTPNDRTHARSLDARHVLEAPSPSSYLDIAFLVALVQKHGIDAVHPGYGFLSESAEFSRRMWHEAGAVVIGPGWRILEETGDKLAAKALAQMCGVPTLPASAQPTGSVEDVLAFARQPSTGGGGKGIRLVRTEPDLESATARAIAESPSRQIFVERAAVDGFRHVEMQIIGDGTGRVRHLWERECSIQRRYQKVVELAPSTIRDREFVGRIIDAAVRMAEAVAYLSLGTFEFLANPDSQEFFFLEINPRIQVEHTVTECITHVDLVKTQLDIAQSVALDALPALAVLTSLVTAEPPAAILRLAAENVHNDWSISIGRIPNFALPSGNGVRVDTHLVPGAPIVVSTDFDSLLAKIIVTGVSWTDVVAKCRRALEDTRIDGVKTNLDALRAIVASPDFANGACNTSWLERELPRLLKTGKRISEDLVSADFSNRDDTSLGSSSSVLLRKGDAWALKLAPKEGTTSKQAPAEPQVHHLKLTCVLRNEFPSLLRAEVELAHSSATTPQTFLLEAASSAASAGSVLAEGKHRRGNAADPSHVVAPFPGKLVEVLVDAGDVVRPGHVVCVVQQMKMELEVRAARAGRVRWVTEAEDGEDIAEGTLIAELDGISDGSVVVVDGDEARAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAN8</accession>
    <name>A0ABR1XAN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674494.1">
        <property type="nucleotide sequence ID" value="XM_066804721.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037781"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="206" mass="22961" checksum="5F715EFFE35112F7" modified="2025-10-08" version="1">MSGSYIASESQRDDGGGIYESGSGESLLLANAYRPCIQLFTDIVGCLSDQASLDPPIITSLQRSRDSLKLWAHGSRRARVGTFRLLVNICRTLLKRLLILVTEDRQPIASQSAVEVGIAIERLRTQIERDIQDSDSDTTSEGFFDNASDPSNIAEDLKTDVRCLQDLGYRFQEKAIRQRSTIHRRTSTQTPQASETPTKYDTPYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAS9</accession>
    <name>A0ABR1XAS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Choline dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674548.1">
        <property type="nucleotide sequence ID" value="XM_066804775.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037835"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF100">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046773341" description="Choline dehydrogenase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="140"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="4">
        <location>
            <begin position="481"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8093775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="627" mass="68461" checksum="7FF980BDA65AE445" modified="2025-10-08" version="1">MLFNKLFSLMAAVVPLAAAVDLDGYEYVVVGSGAGGGPLAARLAIAGHKTLLIEAGDDQGKNQNYTVPAFNAKSSEDEHMAWNFFVRHYEDDAKQARDFKTVYDLPDGGEYIGLDPLRAPSSRDLCTPVLAPSYIAEMTGDKSWSADNMRTYFERMEDKKYLSLLPLSNDGHGYKGWHTISWAPLSIPLGDAGIMSMLLGGAFAIGNLTKSVFDMTTLLAGDANANTESRDQDPGYYQIPISTRDNTRVGSREFVLDTRDAVNSDGSKKYPLDVRMNCHVTKVTFDESVNPPRATGVEFLDGAHLYSASPLSRSAKAGIPGSAKASREVVVAGGVYNSPQLLKLSGVGPAEELKKFDIPVIADLPGVGTNLQDHYEISVQARTDDEWVAFNGCTWHGDEKDSCIDKYENPGLLGDQGVYASNGLAATMYKRSSTAPNNDWDTFVFGGPVNFRGYFPGYSINATDEHDWWTWAILKSHPRNTAGGVTLRSADPLDMPDIMFHYYSEANGEYKKDLQAMVEAVGLARDAFARQPHKTTEVMPGADVQSQEDLEQWIQDITWGHHASSTCPIGTDSDPMAVLDSSFRVRKVQGLRVVDASVYPRIPGTFTAVSTYMVAEKAADVMLAELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAW2</accession>
    <name>A0ABR1XAW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L26-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000449</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674537.1">
        <property type="nucleotide sequence ID" value="XM_066804764.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037824"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="135" mass="15336" checksum="6D1EED298BB3BAFC" modified="2025-10-08" version="1">MTKHLASGTASSRRKSRKAHFSAPSSVRRNIMSASLSKELREKYNVRSIPIRKDDEVTIVRGGAKGREGKVTSVYRLKYVIHVDRVTREKVSGQSVPLGIHPSNCVITKLKLDKDREDILERIKIGRELRKKQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBJ3</accession>
    <name>A0ABR1XBJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aminopeptidase</fullName>
            <ecNumber evidence="7">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_000771</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674859.1">
        <property type="nucleotide sequence ID" value="XM_066805086.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038146"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF171">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="10">
        <location>
            <begin position="12"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="8">
        <location>
            <begin position="250"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="9">
        <location>
            <begin position="541"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8094086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="886" mass="99613" checksum="DE2203979B8F1E7F" modified="2025-10-08" version="1">MTDRDTLPTVIKPSHYDLSLFALDFKNWTYQGKVVIDVEVLEATKDVVINALELKLSSAKLTVTHTKATQTLETSTFSYDEKKQRATLTFDQEIPPTSKSSLEIAFEGILNNDMAGFYRSKYKPVVPAAASVPRDDQFHYMLSTQFEACDARRAFPCFDEPRLKATFDFDIEVPEDQVALSNMPVKSVTKTSEGLQQVAFERTPVMSTYLLAWALGDFEYVESHTERRYNGKQIPVRVYTTRGLKEQGRWALEHAPKTIDLFSEAFDIDYPLPKADLLAVHEFTHGAMENWGLVTYRTTAVLFDEKTSDAAYKVRIAYVVAHELAHQWFGNLVTMDWWDELWLNESFATWVGWYAVNEFHPDWNVWAKYVGDGMESAFQLDSIRASHPIYVPVQDALDVNQIFDAISYFKGCSTLRMLANHVGEKQFLKGVSIYLKKHAYGNAKTEALWAGLAEATGTDVASLMSNWIQKIGFPLLTVAEEPGQISVRQSRFLSTGDVKPEEDETTWWVPVGLQGKTGTQEVQSLALTTKEETIRDVDDEFYKLNHNGFGFYRTNYPPARLAKLGTQLDKLTIEDKVATLGSARDLASAGYGTTPALLAFLQGFGAETSQIVWNQALNTLGSVKSVFSDNEEIKKGLENFTLKLINDAVERVGWEPASGEDFLTGLLRKRLLLTAVVNGHPKVLEKATQLFEAWRKEGLVLSPDLRSVVYRAGVKRSPAEAFEALKKEWETTTSVDGREMCLSSIGHIGDVEILKNQAIPFLFNLSPPAAAADSIPSGDMHYLSTALAGNAKGRAIQWQFMKENWEQVTTKMANPVVLDRFVRLSLKKFTDAKYLDEIDAFFKDKDTAAFDRSLEQVKDAIRGRAAYRQRDAEVLKEFLGANGYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBR3</accession>
    <name>A0ABR1XBR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hormone-sensitive lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674908.1">
        <property type="nucleotide sequence ID" value="XM_066805135.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038195"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025:SF3">
        <property type="entry name" value="HORMONE-SENSITIVE LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="220"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="449"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="601"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="614"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="710" mass="80027" checksum="49D95E5412A9FE1C" modified="2025-10-08" version="1">MIDHVLGRPSVKSRRLQVLGVLAFWSLYLYRGPRHGPPIIRLMSRLSSKSLTAWQTVVLTMMYLYAARNFSTLVGLASPEPMANMYDAAYFRATWVMTALDAGFWTAMRIKSKWLRDLSSLVFSVFYMFAAERADEKVRKVRALLTVEHLRVSWNKSTTPYLNFFQNLVRPRFTRYPPRAIRIPRPSTSDYKEPVSGWLYYDGPVADLEHINKMILDIPGGGFVAMDPRTNDDKLFSWAGKTGLPVLSLDYKKAPEFPYPFALNECFDVYTTIVKSRGRCIGMSGRQVPNIVVAGDSAGGNLATAMTLMIIETILPIPDGLVLIYPGLDMNIGNWMSDEQMSLVQDRRMRVTNKDYLKRKSTQYTDLVGTPHQSDDEDDTPSQIDSSKALKQNEAGDEDGMRSPHPEYSHANPRDWTKLPPATPAPGRRESNSKSYRPQPLRTRLAMASMISYFNDRVLTPEMMRAMIILYVGPHNRPDFSQEYLLSPILAPDILLQRFPKTHFLTGERDPLVDDTVIFAGRLRKVKQAYRSQRASQGLGSFHDISDFDEKDVAEVVLIPGISHGFIQFPTLYPPAWKLIDRCAKWAVDLLNAAEAREKRQEQAARSNRHHHRVESSGDEDKPLEISMTRMRSRTVGDDKANNEGSGPASPPIKVNGESGINTGTPKKKRGQARFEKSKSIVKLNSSDDLLGRRMQGLAGPLTGTGDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDY2</accession>
    <name>A0ABR1XDY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ORC6 first cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001568</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675656.1">
        <property type="nucleotide sequence ID" value="XM_066805883.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038943"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008721">
        <property type="entry name" value="ORC6_cyclin_first"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05460">
        <property type="entry name" value="ORC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ORC6 first cyclin-like" evidence="7">
        <location>
            <begin position="11"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="378" mass="42322" checksum="A448B54460512DA5" modified="2025-10-08" version="1">MSRTLETTLLSLVPTYPSASDLPRPLVDLSSSLLTQSRHNASTLKAEEEVAREYACANLACERLKTSLDLPPIQARPPVPPRIYKRLYTHLDHILPANAVAKSGRVRTPSSKLREAQGLFGSGATIERTHNRGTPIKESSLAQFRSRTDGTPTKSSAKKGIFMCTQMHESRIGRIVLAGMETIVLPRGRRTTDEWVTSNLTPLLAGIAFLTIWQIISLETDNPDPKMYAKAREQVLKAVMKARDEVQVKGFEEDEDEAWEGWSNICTKDIDKAVEKGTKSGWQESGWFGSIQDMVDACGTGKGNQGGSGSGEDGGDDDGDDEIMDRMQMQRGDSMFQGRWVMTDRKREEYRHWKEDIMLRIEEIKKEQEDRMDVDEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE40</accession>
    <name>A0ABR1XE40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RHO1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001620</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675708.1">
        <property type="nucleotide sequence ID" value="XM_066805935.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038995"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04132">
        <property type="entry name" value="Rho4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="261"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="294" mass="32556" checksum="0A6DCF1A1C95B1B7" modified="2025-10-08" version="1">MAQYSNRNSYYGSSSSHPTGEKYDNGLSRKPTGAREQRNTRSSEGTVSTTMSSSTGRESSATHVTEAPAYSKKIVVVGDGGCGKTCLLISYSQGYFPEKYVPTVFENYITYPTHQRTGKTVELALWDTAGQEEYDRLRPLSYPETDLIFVCFAIDCPNSLDNVLDKWYPEVLHFCPYTPLVLVGLKSDLRHKKTCVEMLKTQGLTPVTTDQGMAVAKKMSAQYMECSSKEMSGVDEIFEKAIDTVVFNDRRNLEAAMNEAGSGSSRGTSSSNRNSGGIPGVRAFKKKRRMCRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEG4</accession>
    <name>A0ABR1XEG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675851.1">
        <property type="nucleotide sequence ID" value="XM_066806078.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039138"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8095078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="66193" checksum="9E5B62308FA5A560" modified="2025-10-08" version="1">MSATDSSSEPSPKQQDDVPWARPEEFEAKKGVITHLYDLSGRNLTLKETMRIMEVTCTKRNSMTFTERAYGPFLAEPQLDEDPSALTRLPSFSAKMYKSRISKWKLRKNLKPAEVIELVRQYKEREAAGKSTHVYFRGERMDQRRVREYLRLVHGMSVGPHATASEKRIKIEGITCRTPSPPPTAPQTGIQTPMRQMPIRTPESARTRTRSPGVARAEDESGAAEDGGVWVRVGVLAEDGRRPRRALRGHQCVQCFDDFTALMRNHHPLLWIYTHRVAMELAEQSPEAAQSFARLAWNLSQALNHPAEVTFDQMPSPVSESNQSAEPTLMGAREICEFYRLLLMEQVGLDHSGRSQEPFFAAVRTAHYDMANDVEFGYSAMHRMAKTRPEATTSQTLPPHVGDLKRKEYHAWRTYYNGYYEDAAQIMREVSRPELIEDIAHYPDSLFSYYDTAALLARNRSNQDEEQEQDKDAALGAFRTLIDFSTNEYGLASLQTIDALAELETHLRRRQQQHYHHHHQWDRAAAAAADGVLQEVHAALDLLDYQTDPDLRDVLGESSLSYSSQRVGPSSLEGGGATYPSIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEM1</accession>
    <name>A0ABR1XEM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675859.1">
        <property type="nucleotide sequence ID" value="XM_066806086.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039146"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8095086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="199" mass="22882" checksum="0044CBD537853A9B" modified="2025-10-08" version="1">MASVDPPPPYAEFPPATSGDFFDKFPGNVTMYFRFHADPTKSREEQPWIGIMRVKAANVPQLMKEGFSVAEGNVLHEQGYIAESECTTSPQWMDQYSWSRHIFLRDRQQEPARWAAHLIVRARGVLPDLGEFRFLALTHRNVALCRAVNNEDKLIYRFEWGQGVSTPSTATFRWKDCGRGLDEPEEREDFTTYDACSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEP5</accession>
    <name>A0ABR1XEP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001742</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675830.1">
        <property type="nucleotide sequence ID" value="XM_066806057.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039117"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="34"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8095057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="379" mass="42932" checksum="8FAB8412744D31CA" modified="2025-10-08" version="1">MELRNRTGSQAQASASAQVHQALPERRFDIDPDGDLLLAIGEEYPGATPATFRVDSRALTRPSTVFRQMLHGGFAESHRPARGDWVVRLPEDSPSTFYILLSIFHTQFEKVPQDELKGSRIQLIYDLAITTDKYDLTHCLRPWAHLWSALRLQQVTELNNRKQPGAHNASSYVGLQKCLWITWELGNLAEFERIIVELAWCSRLDDNGSLWSPVTAHGTKAVLFNESFEPEEAFETIHATRQKVVSRLLTPLLSWVETLIPDVAHELRSDTSNVDAMLGATLRSMKKFRLWPMPNRDTYAGSVYQLVATLRAVSESLSSDQQHHYSQLTVKMSDLSRHVDGILRDKIDNNLRPVLQASQVEHLEARGKRTGLHRPAVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQH9</accession>
    <name>A0ABR1UQH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_015400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660599.1">
        <property type="nucleotide sequence ID" value="XM_066819714.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052774"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12191">
        <property type="entry name" value="gal11_coact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033789">
        <property type="entry name" value="Gal11_coact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008626">
        <property type="entry name" value="Mediator_Med15_fun"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05397">
        <property type="entry name" value="Med15_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="307"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="579"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="622"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="778"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="874"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="622"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="677"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="875"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8061179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="977" mass="105933" checksum="A3E5F6D4A2434ABD" modified="2025-10-08" version="1">MRPNNQQSPMNQGNPAFGQGFDPRFNQANQRPQMNPNVRQQMLNAMLQQMPPHMRENFQNLPADKVNEMLAKWTASRGGQVPGRPQAQPGQFGQGNNPMAQFAQGNNPNMPQPNGAAGANGQNPMMVQQQLNRMRNTQGQPQMPNNPQAMNFMNNMDVPQRVLSQLQNIPPEIKKWGQLKQWIPTQPLPQNVGEQLLAFQLQQFRAMLVNKPQLAQAAGIQMPQPGQPAQQPPQGVGAPGATGPPPQVAIPPQLAAAFANIQVTAHEIETARRHDRFKTWDEAKIRSYLVQMKQHQIRQKFGMQMPGQAPQFAQQPAGAAAPPTQQPPAGPGAMPRGPNAGNEAPPAAAPARNSTQGQPRSNRPTPQQQNASPAVPPKNNLKRPSTDDAADVPNNASSTPMQRPPSQQAPPPTKPPILNQAQLASLPPDQRAKYEQLMRNHRAAAQQQPTPSTQEDIERLRQIGAEEQRASNNEQLQDVLMNPEQHADMTTKIQRMVFEMSKLGRALGRWYSLTRDDNRARMFFRMRMRLVRQFKDGEKMTTPKEVFSVKPKDLEQVRAMMESIAKDLAASFPQAVRKTASQQNAADGAAQQTTPGQTSNVQPAQQVPLNAANLEKNSQALNKMHQRSSVTPAAPTTSQPPFPLGAPSPHGLPAYGKAPAVTADNLHLPTSRKKPKTTASASVSPQVSKQASPQMQKQAQSAEMKAVPKAQFQCAMPDCEANSIGFATKEASQAHYEEEHVKPFEDPTRYATENLAFALGLDANGKSTAMAPAAGLEQGASPAGAASMAREASMKRSESSNGARPGVAKGVPGKPAEQQNADATMVKTEGQTPAQSNNMDFGFGMNTIDPQELFQFGLESGGGGAIMDMGVYRSITPNDTPESSKDSASSEPNSDVSEGATLDVRLDLGLDNWQPFDGDAFVNTGAMDMEMSMFDGAQPMGMDNTALAGFTSWDDVNPDFTKPFTLDTSLYSLDTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQN8</accession>
    <name>A0ABR1UQN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_015451</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660650.1">
        <property type="nucleotide sequence ID" value="XM_066819765.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052825"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF30">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04702)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="250"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8061230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="557" mass="61563" checksum="1D77D186B0E26A56" modified="2025-10-08" version="1">MSDKTVSHEMTDTSERLPPGTIRLIDIDGHVVSKHAEGKGQTDILLVPRPSEDPEDPLNWTFRRKILATSCVVVYTTMVAIPASAVYSIVTPIRQDTSLTLTDINNGTGIMFLFYGWGCIFWQAIALQYGKRPVYLFSCLANIIILATAPLCTTSGTYTANRIILGFFGSPVESLCEISVVDVWFAHERPKYLAWYGWSLALTGKLAPMLAGFINYGMNWQWTLWWWAIFIAIAFVYCFFLMEETNYDRKHSSGGQHPPTPPQQASSPVVSETQASPLDTESKTPAPAAPEDREPGEIVWPRKSYLDKLGIRDKKRPNRLLNIAMAPFKGFTYPAVVYAGLMYGANSLVWQGVQNASIGTVYTTQYGFTTATVAAAYSGGVLGSIMGGYYCGKVGRILTVRLARRNGGISEPEHVLYVFCASLFLVPFAMVLYGLAVTYHLHWFSLVVTQTAIAANGTLCVSAALGYAMASYPELSGQMVTTCVLIRNTLSFAINYGITPWLEASGYLRVYCIVGGIGLVWNASLFVMTRYGRRLREATAARYYRDVDYARAKGLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTP6</accession>
    <name>A0ABR1UTP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">General amino-acid permease GAP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_014401</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660903.1">
        <property type="nucleotide sequence ID" value="XM_066818715.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051775"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF1">
        <property type="entry name" value="GENERAL AMINO-ACID PERMEASE GAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="1"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8062304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="475" mass="51008" checksum="546B510FD25C9116" modified="2025-10-08" version="1">MALGGSIGAGLLIASSVGLQRGGPAGLVLAFSIAGFAVWLTMCALGELSASFPVQGSFYDYSIRFISPSWGFSMGWNYVINFLLIVPFETTVMILITKYWYDPNIAWFVPVVLVALFSIAAAGAKWYAEAEHAFGLAKVGVILLFTITSIVICAGGVASDPRHGTGFRYWREGAFQNGIQGFLWVFVNAGLAYGGTEMLGLTVAECKNPVKVMPLAAKIVGGRIAILYILPLFMAGLVIGPDTFKEYEHLGKTSPFVLAIRQAGIPGLASFVNAVILISVFSMANASIFASSRALRAICAQGMGPRFLSRTTKKRGLPITLLVVFAVSMLAFINAAPSGGEIFEWLLALASASNYFTWLSICLSHVRMRGAMKKQNRDLSELTWRSPVGTWGSVVAIVIFAFALVSQIVTAIIPPVPNEDESPAQSISRGILGFIVVIGAWLGHMVITRSQLLIPLEQADLRMNADVPDTRPAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTU9</accession>
    <name>A0ABR1UTU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660953.1">
        <property type="nucleotide sequence ID" value="XM_066818765.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051825"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="51169" checksum="D1A3D79CBF339287" modified="2025-10-08" version="1">MAFVSQGVHTKCYPATSSFVLVLESQVSKEARCDSQAMVNDIETGSHRACTDTDAADPAIELGAYSPSHCKFEPIELCGHHRNLYGTVSTRETRHDGSSSVDVAFQAYSVLANFKHFQERLSMIAPVRHTISTRQVSACWLLEVSVKLHKYLTESDTPDALTWDSAAAYLQQQSLIRGTDRDGDGDIQLSHYFVFCLLWVLLQLDAVPLRHQFPHWELPKRLRQHTPLSDKHGRTSVDEEWVLDPTKLNADILGNILKIGVTWTDTLGAHLDFDDVSNTLYLFRQATFCLLNATPPEEGRTCPKSRRAFKEDQVFNEIPQRDRDRLLQSLCNGQADLASFNRRQKRFYNIKTDFPSLGRGYCPLPSMHNPRSPQLLSSYGGTKGKPFNGGLSGLSSFLDPCLLSCPLLKRYFQRCRFTMLPQKHVHEIDASAVVYWQYRSKTVSYGSIQPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU30</accession>
    <name>A0ABR1UU30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661039.1">
        <property type="nucleotide sequence ID" value="XM_066818851.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051911"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="424" mass="48515" checksum="327EC7636E0AD8A4" modified="2025-10-08" version="1">MDQEILSAMGYDPGESISRLRPYLRWIKSSSPGVRKKEDYLRLFTDVVLHFRREGDQPHHMAIQLYVNELATSQPDHYYFNDTSPGSAERLTSVEDTVLIIIGVWTLMKPYFSPTRGNQKRVVVSFSHRYDIPYSEERAFDQSPSELIRSCGLLPHANESAWSPETAQTSTACVTDQSSVSRTADFSFGLHSGLIESHIIDTKVLNASRLFSLASVRIVWTDNISRHFLLSRSGQRHYLELFALPCALRDRETKNPSKSVISPSLVYEVQSTYANLFNPVRVSSAHEVLVRYTGLRYCYWCLGCASWRARTCEIKMLSQDTFKRNRGAFGWSAQLPYDPEIELLMGQEATSWNQVEFRDLWPRILELDHHLQTARPWNFWILFRDSRDTIQYWTFLFGSIILFLTVVQVALGAAQVAGSGSGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUU4</accession>
    <name>A0ABR1UUU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661286.1">
        <property type="nucleotide sequence ID" value="XM_066819098.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052158"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="750" mass="85709" checksum="AC11724D972A7530" modified="2025-10-08" version="1">MRPKKRNYPGYPYQGVSAVMGSMQSQCQSVPMAAAAPFADSPDVRLMLCSAPPPAPPLPQEAVDTPWQHVNLEPTVTQPPPWGHAAADDIPTATAELYPYLSPPPSHNPSFVSGFPTFSHGSGQPWSFNFQSIDIPLLLDQYPFLYQQDNMQLPDYDSADHNPNNSVDHTGGATASGHEDLEGVYHSDAASTAHILNSTFSLPDPSVMSAANMEPNYRPPINLPASNQEESEWQFVEKEKASPIDGPWQCIPWFLDPPQEVYSSYTAYGTSSPEALSPASHEDPTSQPRPKKRGALSPEERQQTSKTRRMAACVRCQMQRKRCTPNPDDEMGACLTCQEVRQSKKVIHKLDCCRWKLTAATVYRQAHLKLTKRWQGSTMYDIPSSDWADDEIRIIQISEGLCSKPFEIKVRRFKPKPGDVTDRIWTDKHGNSHVVKLPPYAISSVSETCKRFVKYAEENAFEAVEQFANRHDVHPIVQETYKAAWNHMRHVTGTSENIDLRGFMKEFWGFWFVLRHTIGSNQMVGDEHLGMEPETHKDYPFPPGHLSVPRMVCQQFDSIVYDALLRKRRTKILKTLWALMQKKDPQSFETIFFAIFILLHEISATSKDRFRWSRENQIKARYDMEQSMEELHEGANIILTLWTYYRRGLCPDVEDWHSIRNSPPKAKIQLKYVSDDVQKLMIALCTASEGEIESETERPAGWTTSRYARKRKEVRPEADLPFIWERDMHFTSQMFQAGWQPQKQWQRSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV21</accession>
    <name>A0ABR1UV21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661383.1">
        <property type="nucleotide sequence ID" value="XM_066819195.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052255"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="211"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="343" mass="38443" checksum="5795001C3755D344" modified="2025-10-08" version="1">MDLVRQQLGATRNLTRLHFRLRALGRLINPVGEVSPEPQNSVAVDALMSLAGSSTFSVYMAHDALPKATYNIFYRAVRPFLNPTGFIDPAGAPQQLELFHPSSPPKYVNETEGRTPSHESDNDTVAVTTPSGYGPPDDEELPGYPDSESEAFASDRKLPDNNRKRYFRRSSDGSSNRATSKRRLWSPDAEAFVETESLSPSAKTDHSDSRLGAIEARMKQQDERIEALEAENRQCKTRNVELERRVAELEGCVRELQGLESRVDQLGEQHEVLEETVANVDVHQSELEADCSRIGLEVAEIRDMSRDALIDDINDKVQESIGDMVVMYREELKRKLISAIQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV92</accession>
    <name>A0ABR1UV92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661432.1">
        <property type="nucleotide sequence ID" value="XM_066819244.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052304"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="145" mass="16044" checksum="DC90B79E860AA181" modified="2025-10-08" version="1">MSVNLTLPASSSPAIDPYKDLPDPLLPFALFVHVELSDSEELARIEEAFNSQSEGATNVQRAPRHDLSGQPLRAALTEHLDNLVSTRRFDPFYFVAVVDEDWRETGVIIVTMDDGTGDEDDNDHVCKIDQLRVPAEDAGLILVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWS1</accession>
    <name>A0ABR1UWS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_014381</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660883.1">
        <property type="nucleotide sequence ID" value="XM_066818695.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051755"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8062284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="537" mass="60819" checksum="FA25EF3A364BAEA7" modified="2025-10-08" version="1">MSTTLFRPAVLGPVFAIISYVIYQILRSPRVKLPDLPVIGTKPGEWFPLQRARWRNASNMAVATQQAYRQYRNQAVIFPVAGDYDYVYLPLEELQWLLDLPDSSVSMHQRTMDVLQIQHTVMDPELVENPVHHNIVKGVMTRETGNLIPELYDESQHAVSKFWGTEPGVAKEMPVYAAVQQMVSRVTNRVFVGLPLCRDEVFLKTGIAYAMDVPISANILKFIWEPLRPLAALVVALPNRIHTNRFIAMLRPETERRIAMYDARKADPETKAADKPPNDLLQWCVNQAKASGDWYLNRVYSLASRVLLLNFASIHTSSFAMTHAMFDLAANDPAYIEELRHEIKTVLAENDGVWDKRTLQKMHKLDSTMRESQRMNSIATFATSRLVIDPKGITTPSGAHPPGTVVGGPSYPVFHDEAIYPDPHTFKPFRFAEMRQQQEEGSRAADGEKGGRLLLLLLRTMCSAWATTSPDFVAFGHGRYACPGRFFAAAELKLMLAYIVLHYDIEHLEQRPSNSWFSAARLPPMKESLKLTRRADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1B1</accession>
    <name>A0ABR1V1B1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T1</fullName>
            <ecNumber evidence="2">4.6.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011712</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[RNA] containing guanosine + H2O = an [RNA fragment]-3'-guanosine-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment].</text>
            <dbReference type="EC" id="4.6.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease N1/T1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.24" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8064965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661719.1">
        <property type="nucleotide sequence ID" value="XM_066816027.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049087"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.30">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="N1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42104">
        <property type="entry name" value="EXTRACELLULAR GUANYL-SPECIFIC RIBONUCLEASE RNTA (AFU_ORTHOLOGUE AFUA_4G03230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42104:SF1">
        <property type="entry name" value="EXTRACELLULAR GUANYL-SPECIFIC RIBONUCLEASE RNTA (AFU_ORTHOLOGUE AFUA_4G03230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539416" description="ribonuclease T1" evidence="9">
        <location>
            <begin position="19"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8064965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="168" mass="18185" checksum="1937AD34355AC7DD" modified="2025-10-08" version="1">MQLSIVSALTVALGVASALPAEVEVRGTPSNAPVTFDHAPDQSKSFTCGGKTYTGHDIYVSAQRGVALQEISETRGKNQYPHSFDHNDSKGHQLNFPSYCPEDKDRMEFPLIKNGPYDGGKSNTKQGDERVVYFYEPGEVDNNGHAKATYCGIMTHVGAAQKGGFILC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1R8</accession>
    <name>A0ABR1V1R8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Photolyase/cryptochrome alpha/beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_011859</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661866.1">
        <property type="nucleotide sequence ID" value="XM_066816174.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049234"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF18">
        <property type="entry name" value="SI:CH1073-390K14.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00691">
        <property type="entry name" value="DNA_PHOTOLYASES_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="7">
        <location>
            <begin position="108"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="594" mass="67781" checksum="4FE84D72BE010D1E" modified="2025-10-08" version="1">MPPKRKATTSAKGEAEALEAKKQKLESSYTTTKRKNNDATADDPLREPHPFSAEAEENGVVLRKFYPQEMSNARALAYNNNELPRPIEVLVSAMEETAGARKKVQVKDAVVHWFKMDLRTHDNRALWMAGQKAREAGVPLVCMYIVSPQDFEAHLRAPIRIDFMLRTLHVLKNDLAKLGIPLYVETVEKRKEIPARIVELLEEWGASHLFTNMEYEVDELRREAKLVRMCAERSIAMEVVHDTCVVPPGALTTGAGKQYSVYTPWYKSWLLDLFDPPAPNPESAREKVAALFDSKIPEAPETKRLSDKDAKRFRALYPAGEHEAMDRLEKFAAEKIASYHAKRNLPAQPGTSNISVHLAAGTLSARTAIRYARDRNTTKKLNEGVEGIKVWISEVAWRDFYKHVLVHWPYVCMNKPFKPEYSNITWSYNAEHFEAWRTGRTGYPIVDAAMRQVQHMGWMHNRLRMVVASFLCKDLLLDWRMGERFFMENLVDGDFASNNGGWGFSASVGVDPQPYFRVFNPILQSEKFDPEGEFIRKYLPELREVKGKAIHDPYGRGAGVLAKRAGYPPMIVEHKAARQKAIETYKEGIKRETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1Z2</accession>
    <name>A0ABR1V1Z2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661968.1">
        <property type="nucleotide sequence ID" value="XM_066816276.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049336"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="143" mass="15794" checksum="528E2B10A5574272" modified="2025-10-08" version="1">MSRSRIADRSGSPSGDTTPSSATSGHDKARGEAELACEDGHRPAHRRPWRGRVRPACPGLRFEKYCVEEATYGTRSPEPDRPWARCSHLAGMIPTVPATQELGSRKILNALLSAICLTRRSFFSSIERAFKEELRNLGIRSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2Z2</accession>
    <name>A0ABR1V2Z2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662303.1">
        <property type="nucleotide sequence ID" value="XM_066816611.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049671"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="68" mass="7399" checksum="0381E5C50B5A707F" modified="2025-10-08" version="1">MLRDTRNDADTVRLFRTFTLDLTDQEQVKRNCDGCGRLAHLVPRENGGGSGHDGICDVLGNRAGDVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V403</accession>
    <name>A0ABR1V403_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-methyl-5'-thioadenosine phosphorylase</fullName>
            <ecNumber evidence="4">2.4.2.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">5'-methylthioadenosine phosphorylase</fullName>
            <shortName evidence="4">MTA phosphorylase</shortName>
            <shortName evidence="4">MTAP</shortName>
            <shortName evidence="4">MTAPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012666</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-methyl-5'-thioadenosine + phosphate = 5-(methylsulfanyl)-alpha-D-ribose 1-phosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (phosphorylase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.28" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662672.1">
        <property type="nucleotide sequence ID" value="XM_066816980.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050040"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09010">
        <property type="entry name" value="MTAP_SsMTAPII_like_MTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01963">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010044">
        <property type="entry name" value="MTAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018099">
        <property type="entry name" value="Purine_phosphorylase-2_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679">
        <property type="entry name" value="S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679:SF2">
        <property type="entry name" value="S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01240">
        <property type="entry name" value="PNP_MTAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 4" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="5">
        <location>
            <begin position="14"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="62"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="95"/>
            <end position="96"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="200"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="4">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="4">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="287" mass="31696" checksum="AB15E46C80FB4454" modified="2025-10-08" version="1">MSSLPETFDRPVHIAVIGGTGLYKIDGYTPIAQVNPDTPWGKPSAPILILEHNGVPVAFLARHGAHHQFAPHEVPARANIAALRHIGVRCVIAFSAVGSLQEEIKPMDFVVPDQIIDRTKGIRPFTFFEGAWSATMKGDGVKLHEKGTIICMEGPQFSTRAESNMYRSWGGSVINMSALPEAKLAREAEMAYQMICMATDYDCWHSTEDVDVSMVMHYMSTNGQNARHLVGAVLDQLCKQDNSDLVQAKHWEGQSKGAVSFMTKPEGRNPEALKKVQYLFPGFLEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4G0</accession>
    <name>A0ABR1V4G0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone deacetylase family. HD type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661904.1">
        <property type="nucleotide sequence ID" value="XM_066816212.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049272"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF10">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="6">
        <location>
            <begin position="41"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="379"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="391"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="599"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="623"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="659" mass="72066" checksum="1854B9356377582F" modified="2025-10-08" version="1">MAHAAPVDANTNGIALGTPSSKKVAYFYDSDIGNFAYVAGHPMKPHRIRLAHSLIMNYGVYKKMEIYRAKPATRLEMTQFHTDEYIDFLQKVSPENMDNFQREQTKFNVGDDCPVFDGLFEFCGISAGGSMEGAARLNRQKCDIAVNWAGGLHHAKKSEASGFCYVNDIVLGILELLRFNKRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGELRDIGIGQGKHYASIFEPVIASVMQYFAPDAVVLQCGGDSLSGDRLGCFNLSMAGHSNCVKYVKSFNLPTLVLGGGGYTMRNVARTWAFETGLLVDAPMDRTLPFNEYYEYYGPDYALDVRSSNMENANSPEYLEKIKNQLVENLKRTAHVPSVQMQDIPGNFGGTMTDEEEAELDDLDEDENKDVRMTERRWDKNIDKNNEYEDSDHEDMDRANGVSRTSGPKRFQDYPKSNANDDSGAPTPVNGAANGSVIKSKETDDTMDVEPAPEAEKEVQEEAAGISAQEEELKEAQQDSAKLDNDGDVDMSEPAAEEQPKADAVKEEGAEKESAKPEVPAAAAEHDESAATQQEPAKEDAPTASTSSEKAPSESGAKPAEAAKEQATADKPSEPAADDAMEVDEPSKGDESSKDKSPAKSPAPAEKAAEAETETTAAARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5G9</accession>
    <name>A0ABR1V5G9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cdc23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_013175</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663181.1">
        <property type="nucleotide sequence ID" value="XM_066817489.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050549"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007192">
        <property type="entry name" value="APC8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF10">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04049">
        <property type="entry name" value="ANAPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cdc23" evidence="9">
        <location>
            <begin position="10"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="366"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="400"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="434"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="563"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="649" mass="72960" checksum="480057A8F6311468" modified="2025-10-08" version="1">MALNERETIQLRSALQEAVVKCSERCLYQSSKWAAELLNAIPEPQAGFDDPNNGACPAVVLTQNTEPDEAVLEAREINKYLLAKSLFDCREFDRCAAVFLPDSMIASIVATKEASTPKGKGKGKAPASSARSPSAPTLPQISQRSLFLALYAKFLSGEKRKDEDSEMVMGPQDLGACVNKQLLPISRYLEAWFDARKTEDGEDTDSQGWLEYLYGMVLARQKNEELAMYWLGRSVHLFPMNWGCWLEMTSLVSRVEDLNRLMPRLPQNIVSFMFHINTSLELYQHDNNLANSHIPDFVVPTTCDALLSYHAKDLVAAEQHFSRLLSLHPHRLDSLDHYSNILYVMNSRPKLAFLAHLCSGIDKFRPESCVVIGNYYSLLSLHEKAVQYFRRALTLDRSCLSAWTLMGHEYVELKNTHAAIESYRRAVDVNRRDYRAWYGLGQTYEVLEMHAYALWYYKKAAGLRPWDGKMWMAVGSCLQRMGRNLDGIKALKRALLAESYYDTGSSFGSTGSGPMSLRGAHMDPEILLQVAIMYESLDQDDDAKAYMEMRAPQGIMRGESIVIHNDDGSDEDGDGREGGGNGREGTGVTAATSKARMWLARHAMRIEDYTTANRLANELCQDGVEVEEAKALIREVRSRMDATGPDEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5S9</accession>
    <name>A0ABR1V5S9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_013303</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663309.1">
        <property type="nucleotide sequence ID" value="XM_066817617.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050677"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052604">
        <property type="entry name" value="Mito_Tim_assembly_helper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082:SF2">
        <property type="entry name" value="CHY-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="129" mass="14859" checksum="C4AAFC2C29D41A9A" modified="2025-10-08" version="1">MCKHILNAQVSIRSPCCRKWFDCADCHHEQESHPLKQTLELVFACKKCRKCFRKDAQEFEDADEYCPHCDNHFVLEAVTPKPALKVEGEDARVDNRMLKDDRVKDGKQGGDSMAMRTVFDIDKDADRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6M2</accession>
    <name>A0ABR1V6M2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aminodeoxychorismate synthase</fullName>
            <ecNumber evidence="4">2.6.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Para-aminobenzoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">p-aminobenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_012436</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11672"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58406"/>
            <dbReference type="EC" id="2.6.1.85"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 4-aminobenzoate from chorismate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the anthranilate synthase component I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.85" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662442.1">
        <property type="nucleotide sequence ID" value="XM_066816750.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049810"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF18">
        <property type="entry name" value="AMINODEOXYCHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="11">
        <location>
            <begin position="8"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="12">
        <location>
            <begin position="509"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="690"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8065689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="844" mass="92669" checksum="C38D91B48306B528" modified="2025-10-08" version="1">MSRPRILFLDAYDSFSNNIVSLLTELLAADVDVLSIDAPELAPASPGFHDALRQKLRHYHAVVCGPGPGSPTSPADVGLMKHVWELEDQHLLPVLGICLGFQSLAVSCGAGIRKLSTTGLHGMIRVIDHRPHASANDIAEGNIFHAVPPFKATLYHSLCADVGQDSVSDADWATMRWTLPAKTPDVVPLAWVDEQRPGFVERILMGMRHATKPFWGLQYHPESICSEPAGHQVIKNWFSEAIRWSAARGRTVEPSFSLPQSGSTKPCLLSGPVLDPRRWEEHKRWLPSLDGSSKYSYKTISLPPHIEAPDIVEILQHNSQEHIILDSASAHAKRIGLDVRGRYSIIALDVDEALRFEYHVGDKTATIRVPSQGDAALQSVNLGTSSVWHVLAEFLETRRVSLGLECIDVDIVEKRQHTRPDLSFSWITKSIVIDHLEGTIRIQSLHPSPVEASTWLEETQNTLESSTLWSDGLRLNTDKIKDIDNLTPPITPTVTPPAPTIVLPEPFVYDSKVRQCQDFIAAGDSYELCLTDQTTIERTKSPHEAAATGLPMTNSWAPPSATKVPSSWQLYRSLRSRQPAPFGSYLRLGGATLISSSPERFLEYTADGLCSMRPMKGTVRKSDTVATLAQAEQILHVPKEEAENLMIVDLVRHDLHSVCGPGHVTVPQLLKVEEYASVFQMISVVEGQLPATTNSSPLNDNDDTTTATASPRRHHYTGLDVLAASLPPGSMTGAPKKRSCEILQGIEGAHHGERSLYSGVVGYMDAAGRGDWSVTIRSLFRWDDETVASPRDGPETEVWRIGAGGAVTALSTPEGETEEMLVKLKGPLGIFSEQPQQQQQQSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7H0</accession>
    <name>A0ABR1V7H0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Myosin head (Motor domain) domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_013886</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663892.1">
        <property type="nucleotide sequence ID" value="XM_066818200.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051260"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15480">
        <property type="entry name" value="fMyo2p_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01380">
        <property type="entry name" value="MYSc_Myo5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046943">
        <property type="entry name" value="Fungal_Myo2/2A_CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036103">
        <property type="entry name" value="MYSc_Myo5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004009">
        <property type="entry name" value="SH3_Myosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF706">
        <property type="entry name" value="DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50084">
        <property type="entry name" value="Myosin S1 fragment, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51844">
        <property type="entry name" value="SH3_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6 9" id="KW-0518">Myosin</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Myosin N-terminal SH3-like" evidence="13">
        <location>
            <begin position="6"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="12">
        <location>
            <begin position="77"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="Dilute" evidence="11">
        <location>
            <begin position="1188"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="9">
        <location>
            <begin position="651"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1003"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1061"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1516"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1007"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1074"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1517"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="162"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8067139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1538" mass="176009" checksum="5CE6F816D0107E36" modified="2025-10-08" version="1">MSSNFDVGTRAWQPDATEGWVASEVVSKQVDGGKVTLVFKLENEEVRTREKIELSVEGLESGNDPLLPPLMNPAMLEASDDLTNLSHLNEPAVLQAIRLRYIQKEIYTYSGIVLIAANPFARVDSLYVPGMVQVYAGKQRATQAPHLDMLRDKKNQTIVVSGESGAGKTVSAKYIMRYFATRESPDNPSGKTKKGADSMSETEEQILATNPIMEAFGNAKTTRNDNSSRFGKYIEIMFDEGTNIIGAKIRVYLLERSRLVFQPLKERNYHIFYQLLAGASDAERKEFTLLPVDQYDYMNQGNAPVIDGVDDKAEFEDTKRSLSTIGVDATQQQGIFRLLAGLLHLGNVKITASRNDSVLAPTEPSLEIACALLGIDATNFAKWIVKKQLITRGEKITSNLTQQQAVVVRDSVAKYIYSSMFDWLVEIINYSLATEEVMNRVVSFIGVLDIYGFEHFAKNSFEQFCINYANEKLQQEFNAHVFKLEQEEYVREQIDWTFIDFADNQPCIDLIENKMGVLSLLDEESRLPMGSDEQFVTKLHNNFAGSGEKHKFYKKPRFGKSSFTVCHYAVDVTYESEGFIEKNRDTVPDEHMEVLRASSNKFLGHVLQAAASVREKDLAASTSVAKPAAGRKIGVAVNRKPTLGGIFRSSLIELMNTISNTDVHYIRCIKPNEGKEAWKFEGPMVLSQLRACGVLETVRISCAGYPTRWTYEEFALRYYMLVPSTQWTAEIRQMANSILTKAFGETIFFRAGMLAFMENLRTERLNSCAIMIQKNLKAKYYRTKYLEARSAIIRFQAFTRAYITRRRAQELRKVKAATSIQRVWRGQKQRKKYLRIRNNVVLAQAAAKGYLRRKEIMETRVGNAVQLIQRVWRRRMQMREWRDYRRKVTLIQSRWRGRMARKEYKQVREEARDLKQISYKLENKVVELTQSLGTMKKENKTLVSQVENYENQIKSWKNRHTALETRTKELQAEANQAGIAVAKLQAMEEDMKKLQVNYDESNSNVKRMQEEERELRESLRSTNTELERIREETQAHENEKQSLRQQLNDLQDQLELARRAGPINAELKATKRRSVGEEPRGMDRFSAAFNPRPVSMAVTGAGQRQYQPTGFVPGVDSIEMELESLLADEDGLNEEVTIGLIRNLKIPSPNNNPPPSDKEVLFPSYLINLVTSEMWNNGFVKESERFLANVMQSIQQEVMQHDGDEAINPGAFWLSNVHEMLSFVFLAEDWYEAQKTDNYEYDRLLEIVKHDLESLEFNIYHTWMKVLKKKLSKMIIPAIIESQSLPGFVTNESNRFLGKLLQTNSQPAYSMDNLLSLLNNVYRAMKAYYLEDTIILQTVTELLRLVGVTAFNDLLMRRNFLSWKRGLQINYNITRIEEWCKSHDMPEGTLQLEHLMQATKLLQLKKATLNDIEIIQDICWMLSPNQIQKLLNQYLVADYEQPINGEIMKAVASRVTEKSDVLLLQAVDMDDSGPYEIAEPRVITALETYTPSWLQTPRLKRLAEIVSAQAIAQQEKLDDEYEGDGALTEDVEGEAVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7T4</accession>
    <name>A0ABR1V7T4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663976.1">
        <property type="nucleotide sequence ID" value="XM_066818284.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051344"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8067223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="52806" checksum="29F1764B01F31C58" modified="2025-10-08" version="1">MALVSLPTELLQQICREFCLHCQLDKEPDTFLHGEIEWYNDVETVAADGAVVRNDQDVQLKQLKQRDEEEWRTIPEAQQSLLNLCRTCSVLRTMAHPYLFHRVVFRTAQANHLFDLLWNFLQRPDLAACVKHLALGPEANAGEAPIWTADVIERLLHSALRSIRLDPELPVVRETVHVVTYPLLSQLVIAHTRSLELLELSGELDGSWNLLAYVHPDKCSLPRLRGLDLSGLDTPYDLADYAYLLRLAPNLAKLSVTTCGAVSRKLELANLQTLSLVNTTLDRSDMDLLLSSCHALRTFSALFVSSDGAGVPEIVDLLAQHGHGRTLLDLALVASISDREVWRNDGEAIRSLAGFERLERLVLDNRYVVEITAQEQDRYLLQTAPGTLRSIRLNGTEERFLDELDRLADRKAGGMYPHLTEVVVVSPDSPVWEWSHPRCEEILNRMEGLGMPLTEDELKRPQWVQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V840</accession>
    <name>A0ABR1V840_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014121</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664127.1">
        <property type="nucleotide sequence ID" value="XM_066818435.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051495"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="323"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1181"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1749"/>
            <end position="1792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1769"/>
            <end position="1792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8067374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1792" mass="198872" checksum="13961DC437FD2189" modified="2025-10-08" version="1">MELTMVLSTMTRMFDRVYIIVDALDECGEYTASVVETLASYANDHDNLCAALLSRDEDEIRFGEDVAEYVSSEIQERVRTGRLRVGDDDLLSDIQRELVAKAHGMFRWVTCQLDHLGECHSDRARREALDTLPPDLEETYVRLLRRIRPSQESLVAMTLNFVGYISKDLSIPMLQHAVSIRPDQRSLSTQDIIYEEAISRACSSLVRKTNDGEYFEFAHFSVREFLESERLDQIQLDRFRISRSLCSEMFASQCLRYIQLENFIQGVSEAGFKYRKAFDRQKTKAFIGWAVYLLHGLHDGSRRDSTGNYQSPDLDLTLAVHDERFTPLHLAAILGLSEICQKLLSEGADPGLPSQLGTLINCAVSSIGALHRGEDLHSLPELPYCIRQCHRADAQTNPHDVSKTVCCILEAQRSTLPTNALTANPTLMRNALATCGAIADFSMISTLFRNGVEPADEDRQIFEDQLLTLCQNITDLYTNENSPSTPGFVKSALETRLEAFIRSLNSFIHVSPSAFAFCSLAWMVAMDEDVSFTSDMGSRGGDINKLKTYLDDPRISSNAQDTQRGFILLHWALEGSSVELRGLAGRLTVTHQLLESGYLPTAVDLEGQTPLHVWSWREDTIDETQQQELEDLMRDLLEKGASIQSRDGSCGATALHNWASHGSIPILRAALHVASADDVETALAMIDNDGALPLMKAIESSHIDTANLILCSKPHTRHDFETLDRSKLLSLAGGIKSASLLCDPIALGFPIISDDGDTALHHVKGTTTAHCIKVLKEHLPDYCDKRADGRLPVEGAKGHEQCAEKQIPYLKAIEQLTTPTTLTGRDENGLSVWNYAVTCVHQDETPSTQRCSVVCTGLGYALQLGYMKSHEKSSSACGLIPLIKALDLPAEKPYESWSVSPEFLMDVINVTDYWPQFRDSPMALDLLKSSYYPSIHVPLFQLLLEKGVFPGNHEPCEALRSIRLLYFPELDERYNVFKEQSQLILDRAPKSAWNTTDPAEEESGLIHCTRSVWLTEELIRRGADPNLRTSLRHGNVPALVHHILRGRPKVALCLLKNGARADETGADGVNAMHAAVITGNLGILESILPILSFTEHPSWISWCTWACYGEAWTLNLLHLNAFIGQLDCMKFLFQNDKAGKFKQQPDRAWQAMHLAAMGGHDSIIRYMHQHGFNINTRWPDNGFTPLHSAVNQRKISAIEELIGLGAEFLQDRQGKSPLYLAMVMGFPDIVEIFDRRLAKANDKGIAQPSPPPSTNHRLLPLFEKAVQKGDITLCQRLHRLGCLIDGHLTCGGCSLLILALSYYQGPVARWLIEEGACPTKIGCAKHGGASIVELCLGCTSFDIGSTKILMTKYIQQGGDILDTRLICSAAKKDNVNHAETTSKMIWQVEGVDILVIAYYATENTGSKAILADYIADALPVGEPCPPSAIIPLFHGKWKTRLAGGKFCSTSMWKSLDIYGETPIMICSRESNLDAMAFLVNREADYQKTNINGESILHLAAEGRGLGGFSLSLMLGVDPHIKDIDGISAIHKASAREGLTATLVNHDLRLGDTDPIPWSPCVYLFGKFPLFHIHFRLYQRKLGKVKLLRIANLHPGTGWSPLCLMTLRQDLRGMGHALDIGATIDHEGSSEGSALMVACTAGAFAAAKFLVRRGASICYVAPDGQSRSSLVAATASSSLAHWLLVDRFVEQPKICFSAAMEREEEAYKPWSGGTRAGYLIMGSDERDPSESSFDYYKRLMEIRRNMRGKVVPPADRGKASRPSRLIPVETIRRHPEDMRSPRDEHKDGVSDWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V850</accession>
    <name>A0ABR1V850_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pre-mRNA splicing factor ini1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662906.1">
        <property type="nucleotide sequence ID" value="XM_066817214.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050274"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005345">
        <property type="entry name" value="PHF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13120">
        <property type="entry name" value="PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03660">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016468">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="109" mass="12277" checksum="A38E2359F5C40C74" modified="2025-10-08" version="1">MSRHHPDLVMCRKQSGVAIGRLCDKCDGKCPVCDSYVRPTTLVRICDECSFGNYQNKCVVCGGEGISDAFYCFECTRLEKDRDGCPKIINLGSSRTDLFYQKKTNRTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V880</accession>
    <name>A0ABR1V880_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664126.1">
        <property type="nucleotide sequence ID" value="XM_066818434.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051494"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="210"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8067373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="34717" checksum="9EB1CD3B5D1C715F" modified="2025-10-08" version="1">MADPLSIAASIAGVVTLADLVFGRLYKYVKTARDAPNEVKELAAMVNDLGGLLNSLARLARALQGETFDVSLRMQHADTCSFILSKLDKIFQKADKDLEKSGQLDKFQRKLKWPFSTSQIKEYVSELSIHKESMSLALSADSMNGLLQCLSFERKILDTTEEIRLDVKETRKITTLIEESSERTKVLESFLKHNPQESYEMSLSLRHPRTGFWLLRLPAFQTWLENPGSKLWLSGITGAGKTVLAASIIEAALARSNENVAVAFYFCDYKTEATWNPNTCHTQIQQSLCRTNWHAASAQQGPTFRKGYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8W2</accession>
    <name>A0ABR1V8W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 6">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_013488</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 6"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663494.1">
        <property type="nucleotide sequence ID" value="XM_066817802.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050862"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16207">
        <property type="entry name" value="EFh_ScPlc1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="413"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="PI-PLC Y-box" evidence="9">
        <location>
            <begin position="796"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="920"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="167"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="689"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="757"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="711"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="767"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8066741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1146" mass="127380" checksum="475BEDC74384AF1D" modified="2025-10-08" version="1">MPSLPTSHPRSSPDPNANSTTPPMAIQGSSQGSLQRRRRPSQVQTAALANTKLSSIPSSTMSASSMASSLPRDSPLMTPEYAALMAGGSVQASPEPFPFLGREVDQFPPTPLMLGDPLIIRDHQLSRMPSVNSMNPSVAPSANSLAEALQGRDRDTKGGLMRRLSSRAKKLAPTRRQSSVTPAGRDGTIGPAILRRRSDSNNTAPPETVFYSDSDDGFTDERDEYNALGLMNGSLREVSSTSNPGSNTGSLSPVGAHAGPVIPLALIKGTSILKVSKKRKYKKIFLVLDSEAAKIRVGSDIRQYRLDFEVPESEEGRFFSILYAVADKSKSKVMHLIAEDEETFDNWVNALDAISKHRQDLMTSLMSFNEKAIRAYWASEMTKQFEGRPHSFDDEEIDLPGVERVCRNLHIHISSEQLQSKFTLADATKTGRLNYGEFQLFVREMKRRDDIRAVYRGAAITDVETGITWPEFAAFLRETQGEDVDANPRGWEAKFLRFARRPKPTAGELGDGETPLPRMTEQAFAAYLTSTYNLPLAREPAEYSLDRPLHEYFISSSHNTYLLGRQVADLSSVEGYITALVKGCRSIEIDCWDGSDGQPQVQHGYAMTNAISFREVINIVNKYAFVASPFPLLVSLEVHCNNAQQVLMADIMKEIFGTRLVTTPLDSSSDKLPSPSQLKHRVLIKVKAAAPSVDESRKGRTPSSTGRRRGNSLTNSLTSPYTKPVAADNGAVPAQYLSNSPLLSPRESSRLRVGKRYNTITEGEVQDTVSSNTSDNDSGSEGAPNKKKTSKIVPALGELGVYCMGVKFDGFAALDCKMPFHILSFMEGTFSKHTKTKEYKDALYRHNMRFMMRVYPQFNRLTSHNFNPLMYWRKGVQMAALNWQTFDHGMQLNQAMFEGGTDQSGYVLKPHSMREIRMLREGLPDEAVGKLERKNVSFTIDVISAQQLMRPGNLPANRTVDPYVEVEVFHANDKRDKHDSSVGIPTPTDTPLKYTTKVVRENGFNPVFDYKCHFKLTTKYPELVFVKFSVKMSPDGEKRNERVAPMATYTAKLCNLKEGYRTLPLLDPNGDRYLFSTLFCRIERGPVTNVYVNPGDESEPVGRIKTLGNKVFNRSYNSNPKLAAEKTVEKSSFDSGYSDSSLVRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9X3</accession>
    <name>A0ABR1V9X3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">X-Pro dipeptidyl-peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663808.1">
        <property type="nucleotide sequence ID" value="XM_066818116.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051176"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF10">
        <property type="entry name" value="COCE_NOND FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="2">
        <location>
            <begin position="321"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="574" mass="64633" checksum="3CFEA07DEA062871" modified="2025-10-08" version="1">MEVQTPPLRDLQTTTDDHENKLRFLKNVSIPLKASKLPIRANVYLPLTDDASAKFPVLCTYGPYGKDIPYATFFVGSFNETPDPVFWTSRGYAVVRADERGLGQSPGFLDTMSKGTSECFFDVVEWAADQPWSTGKVGLLGISYYAGTQWRVAARRPKGLAAIIPWEGMSDYYRDRCQHGGILSDKFIGVWWNRQVLVNQYGKAGRSQLKFPPDGPGARGQEDTIEGDLPEEVLVANRQDQTVDNAKYKYRDEEYYASKEFKPEDIEVPLLSVANWGGILLHLRGNVEGYNHAGSKFKYLRFITGRHDLPFYYKEEAELQQSFLDAFLKGEDRVGWSVPGKVPPVTVTLRKGNVGFNDAEKEKAYPKRQEEAWPIPGRKSKKVSYKALGTLDNQQAVQFTTPPFEQETEITGHVTAHLNVSLTPEEASGEKDIDLFVTLRHLDADSKEIFYTGTAGDPVPLCKGWLRVSMRKVHDEHPKHRPYLPYREYFSGDVQPVKPDEVYGVDVEIWPTNVVVDKGNRLVFEVASGDTQGSGIFQHNSPTDRPTSKFAGQNHIHFGDGLENYVTLPVIPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGP2</accession>
    <name>A0ABR1VGP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-arabinono-1,4-lactone oxidase</fullName>
            <ecNumber evidence="2">1.1.3.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L-galactono-gamma-lactone oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010612</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.37" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664217.1">
        <property type="nucleotide sequence ID" value="XM_066814927.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047987"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="44"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="542" mass="59878" checksum="89FC169A86A043D3" modified="2025-10-08" version="1">MAPSSPPAAMDAQAQTIIDQVVGKSGIPFHARSAYTHATWAKTFSSLPELYLEPETQEEVEQIVKLARLCRRRLTTVGHAHSPSTLTCTSSWMLSLDKMNRILAFDGATGVATMQAGIRLFQLSDELAARGFAMPIMGSVNEQSIAGVISTGTRGSSLKHGLLSESISSLKITLGSGKTVRCSAAEDPDLFRAALLSLGALGIITEVTFRAVPAFALRWHQTIDADARILATWDTTLWTQADFVRADLDSGKEKLRDPPVGYYDGALGYHIYHNLLALSRWVPRIVPWIEWFVFGLQYGFRNGASTTTSAVQPSARAFWMNCLYSQYVTEWAIPLARGPRPLARLGAWLNRLKPGDPGYVDHGIPFSAEGVYVHSPVEVRVCDGRARTSADQNNRPWLDSTVKDGPTLNINATMYRPYLRDPPGLERWFAGFEWLMRDLGGRPHWAKNFGVTAQELADWYGDDLVQWRRVRDAADPDGLFVGPWHRQHVLDPEAPRYRAEEVESGRVSVGPRTGVTVHGEVQRVKAGDAEVHSRQDSGVSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGZ0</accession>
    <name>A0ABR1VGZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664287.1">
        <property type="nucleotide sequence ID" value="XM_066814997.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048057"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="72" mass="7964" checksum="965B5FB17D410363" modified="2025-10-08" version="1">MGYSSTTKMSSSSEKKSSSSSSKDHTSRVNDWIHQDPRDDPWSSVNTYYGKDSSSSGDKKKKHHHKSGGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHJ7</accession>
    <name>A0ABR1VHJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010909</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664514.1">
        <property type="nucleotide sequence ID" value="XM_066815224.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048284"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="84"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8070706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="370" mass="40809" checksum="5F4E74101EFAA054" modified="2025-10-08" version="1">MYNDTAAREGFASALVAMSHTQDLSEDLCTPTRLLVIVITILTTIFVVLRFLGRWRHGMQFGADDWTCLLALVLLYANFGVHIVLFAGELLYVTSINTYKISLLFFYWRTFPVRAMKIGGLVLGIFSVVWTFVAIFVIIFQCLPVTKAWQPWAEGTCSNLLHTEPAMAGMNIFCDVAILCLPIRPVMSLRINAAQKAFVIGTFLLGSYVVFTSCYRLAMFFKFDPTDATYTLAEAQAWDVVEMASGIISACLPTLGPILKTMTNAILTNTRFSRRMSALGPARTSGPKQDLHLVTIGGSGSSCRSPRSPHWSSHDKYGAIDDIEADCADEGSPWSTCRPPTSLLPARSPCSCGTGPVWLLILGHRKPRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHL5</accession>
    <name>A0ABR1VHL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664496.1">
        <property type="nucleotide sequence ID" value="XM_066815206.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048266"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="185" mass="19188" checksum="B797CE3C76D141B5" modified="2025-10-08" version="1">MIAPSPPNPVAIVAAQPPDHIKRQDLVVLTQTIVTPDSTRTAVITLGNGGHPDAGPAATSAPNDPPPSSGGGSKDSTAGGLSPGQIGIILGCCLGAVVVFIVLWYCLSNARRRREAEMSETPSYDSLDYTYGSGTTGGGGGPGQPDVSYWPTWRSIPPPVVPTYTARDPGRQWRPSARASATVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI10</accession>
    <name>A0ABR1VI10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664590.1">
        <property type="nucleotide sequence ID" value="XM_066815300.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048360"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF1">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pleckstrin homology" evidence="3">
        <location>
            <begin position="2090"/>
            <end position="2158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="679"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1764"/>
            <end position="1866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1882"/>
            <end position="2035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2180"/>
            <end position="2215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2302"/>
            <end position="2321"/>
        </location>
    </feature>
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        <location>
            <begin position="2327"/>
            <end position="2352"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="201"/>
            <end position="235"/>
        </location>
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    <feature type="coiled-coil region" evidence="1">
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            <begin position="267"/>
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        </location>
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    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="338"/>
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        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="796"/>
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    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="873"/>
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        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1336"/>
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        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1566"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2269"/>
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        </location>
    </feature>
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        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="431"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="494"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="506"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="535"/>
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        </location>
    </feature>
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        <location>
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="2">
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    <feature type="compositionally biased region" description="Polar residues" evidence="2">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
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        </location>
    </feature>
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        <location>
            <begin position="1787"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1886"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1937"/>
            <end position="1946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1954"/>
            <end position="1965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1998"/>
            <end position="2008"/>
        </location>
    </feature>
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        <location>
            <begin position="2009"/>
            <end position="2021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2202"/>
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        </location>
    </feature>
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        <location>
            <begin position="2336"/>
            <end position="2352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2352" mass="257533" checksum="3EF30DBA61FD0687" modified="2025-10-08" version="1">MVSCGRRAPSSPIPGFAFQNDPFDEPVSPPTRDGARQRFANFDSQLLALGPNASPDQAKRALEAHLAETDRRMEEAGRLGTALVAQRRELEERLQEVVDQQAEGELSEELKEKLVEIEREYNEVARESARAFLPKARVPSNEGGAEGSLVPEGRGGRRSVSPSKFETQAVASPAKLSVPNRKVRNQPAQRVHDIEFAAEISTSLIAQVRNLQSILAEKEEELRDIKIERSRLEYDAEGLHQRVKNLDESESRYKDENWSLETQVHELMAAQKEAADREKKLQQSINNLQSEKNTAQRELDEVKMNHARLADEYTAAVKTHDVELGAAKRNLVMADSERFALNRKIEDLTSQNQELARAISSQRSRMSDRQENFGMSEDELKAASSGDTPDDSPPPSPVKGTPLRHSMLESETLKTSLSHAQRTIQSLRTNVHREKTEKLELRRMLQDARDELEKTRQDPMPEKRRPRKSETSKEFKKPPPRLLGNLRPVRSEIYIDEEDWEDQTDDGTITGNRSFSRQRSSIPPVAESIETDDFETAHETSDNEREFDTANDRSGNTTDDFHTGAEDFSSSDDAMTETDSPSKNTLRGRRQPSQLFTHNGHPDSTASTDDEYGFDGRRTPTSQFPPFQHKFPARVGRGGFRRSRQGSEDPSFQSPASYTQSSAATTPQQGVQNLAAELGDFDGSDNESNRSATPNRSIYSRPGSIRCRTVSPPPPVPPVPAMPRMLMVNSSMMTEPMQELPANALATMGDRPVSMNTVVSHFAPSEYSEMGTQYLDDNLAKFPSPPTSARDPGLSFEDAENLKQEHARQIEQLHAENANAHATAVDSLKASHADAISRALDEAKSRHAQEVENMKLTHAELANKSAEASAAHAAELEALRADHAARIAQIESELQAQHSSELETLRANHEKELASAKKQSDTAHRAELAALVAAHAAQIELAKKQLSANHEKDLESLKAAHAEQIDLSKQGSDEAHAQELEKLKAAHLAQIDEANNNLRATHSQELEALKAAHATQVEQSQNAASSAHAAELASLAAAHAQELKSAKTESDDSFAKQIGLFKATHEEELRTSKADADAYLARELESLKATHAEQLQSTKADGETTLARELEAIHTKHAQQLQSARDESSARLDREMEGLRATHAKQLEESKQESQSAQAAAIAGLAATHAKTLEEVKAKNEASHQAAVESLKTAHSKELEDFKLERDSAQAAAIAALTASHAKEIASTKADADAEMANQLDSLRKSHSQELDALMDSHAKELASLKESHSTDLATLKAEHAAASAQELESFKAALSKQMESTRSEGDAAHSQQLEAINAAHSEIVEAHKRDSAAAAAALETAKAKHAQQLEAVKANHERQLETLRSEHEAAKSKELGNIFSNHEAQLAAATAALLATKGKEIDELRSTHNNQLAKLNEEHNAFMAKSQQQASSEHAAQLEAMQVELAAVKAKELEALTSAHGKQVEALQAEYAAAKAKDFEDMTSAHEKHVQNLRTEFDSTKARELEEMSKTHEEAIKALKAEAAASKLAALEELSASHGIHTKSLGAEAEAQKAKELDELSAMHAEQLKARQAEHEAAMVKLKEEMAASHELKLKALGSETGASQARELEALRAAHEKDLAALREEHEASRAKELDELNMRHGGLLESLRTEHKTALDRALANLKATHDKDIDSLNGTHASTTAAALEALKSNHSKQLDVLKSEHEADLAQHLDSIREEHRSQLEAQKSGSLAEKEALVASHALELEALRKSLAVARPSLNYSSVSAVSTEPIEQTNEEAGSLRSPKRDAFIIPRERDPQTPAGRRNKDKSAVPFIAEDETRQSPSSVTAGPETPESQRPFKEMSTNTDARPSRKPKVPTSDNSCQTALTLEGIEHLMIKKQHQRTTSSDSVTHTPYVATPGSPIRHHQRPSQESARGDSGLIAGAEPIPARRPGSSASAQSSAQTVPPLPANHRRPSKQHAQVHRAELALGAPWDRRWFPPLPTRTVEDPGRRPRLGTPTPRAGRTNSALGNAEFNSPTRGPGRSRQSSLSSFTSEIDTRFNTHGGTMGVDMGDLAGTDPRMIQAITQTMIGEYLWKYTRKAGRGEIDPSAAGKAELRAKSVPIEAVRVVSDDNPMPPGLHRKSLVIISPGRTIKFTCTTGQRHETWFNALSYLLLRTGDEGQADTEEIAGNITQDDVNEFNPAMGQRTTNGSRPRGPASLSSYNSRTTRTESPNVDMMAIPTLTPTHERTSARPGTIGRLSRYGSGLFSSVGRKSRTGVDNAIYEASEVNDSAEELRQIIEQQDRESDRLENVRACCDGKHDVGTLSHSSKRNRHSSANHLAAPAHNHAHPGRSTTPTPSIPTTSRSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI81</accession>
    <name>A0ABR1VI81_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rad21/Rec8-like protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011108</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664713.1">
        <property type="nucleotide sequence ID" value="XM_066815423.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048483"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21789">
        <property type="entry name" value="Rad21_Rec8_M_SpRec8p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039781">
        <property type="entry name" value="Rad21/Rec8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006910">
        <property type="entry name" value="Rad21_Rec8_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585:SF70">
        <property type="entry name" value="RAD21_REC8 N TERMINAL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G02900)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585">
        <property type="entry name" value="SCC1 / RAD21 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04825">
        <property type="entry name" value="Rad21_Rec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="194"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="300"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="420"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="487"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="514"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8070905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="687" mass="75415" checksum="AC0EFD9B6C09F513" modified="2025-10-08" version="1">MFYSHEILTDRQYGVATIWIVATIGSRSQTKRVTRKAIQDVEIQKAVEKIIEPGAPIALRLQGSLLFGVSGVFKQQCQYLLTDAQKVNFHMNAFFKNMARNELDPAAGQGRRENLMIMDDPDFASGFIPQMPAFNANADMYLVNSNGRNNTQKTSSQMSPPSLMPPGSGSASSQDRFELQLDVPRSDTPDHNFLPQGLQGLSSGQKPAPLGGMGDVFGEEELGPSADWGLNIAEDGSIVENAVVEPDIFGEELDLPPMPSIEGGDNFPQLVTQQPKIDDQGDIIMMDEQPLPDVEALPQDERDDQKAYDQTSPEPDKQGTTTQRKRKRRVILPDDRLEISRNDLRDWQDPDAYRENCCKPKRRLTTATEARKNAIHLTFGLGLANIGQNLGIPGMIHPLAVQYSGDSLFTAMTGLEVFNDQDRGGRKRPRSASEGIEDAESEERRVRPRLEEQGDVEHHQGRGDQNGDNVFALGDDGLDQLSEIGRERQSALDDHPSSAHPWDRHSSAVPGSSVRGQQPQFGRDQPSSPLNKRAGSVQDIVRYSDSGDVGGGDLGFGFGGVGGDSNGSGSDRGGFFPLPAGGGNNGLNPQKGNQYAREFLDREGANFLSYIEQTIAESGERRHDEDFELQRKWIGFDDVFVPARTGRATAQAFYHVLGLVTKGIMMVEQVGMPQEPFGEIHVGIKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIH2</accession>
    <name>A0ABR1VIH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PG997_011206</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 17">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">In the C-terminal section; belongs to the NAGSA dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">In the N-terminal section; belongs to the acetylglutamate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664811.1">
        <property type="nucleotide sequence ID" value="XM_066815521.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048581"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04252">
        <property type="entry name" value="AAK_NAGK-fArgBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23936">
        <property type="entry name" value="AGPR_C_ARG5_6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd24149">
        <property type="entry name" value="AGPR_N_ARG5_6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04263">
        <property type="entry name" value="DUF619-NAGK-FABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058924">
        <property type="entry name" value="AGPR_dimerisation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041734">
        <property type="entry name" value="NAGK-fArgBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011241">
        <property type="entry name" value="NAGK/NAGSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006855">
        <property type="entry name" value="Vertebrate-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342:SF0">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04768">
        <property type="entry name" value="NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22698">
        <property type="entry name" value="Semialdhyde_dhC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036440">
        <property type="entry name" value="ARG5-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51731">
        <property type="entry name" value="GNAT_NAGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 17" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="11 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="15 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16 17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12 17" id="KW-0521">NADP</keyword>
    <keyword evidence="9 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="19">
        <location>
            <begin position="340"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR036440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK8071003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="874" mass="96372" checksum="3E8B88637336F526" modified="2025-10-08" version="1">MLSSSRLAVRAVIRAGRRSATTRISGAASPIVTRRTIAAAYSTRPGRANNYDARHAVIQVLNSVGSKREVQQYLSHFSSVSSKQFAVIKVGGAILTEHLEELCSSLAFLYHVGLYPIIVHGAGPQLNKLLEEAGVEPQFEEGIRITDGKTLGVARKLFLAENLKLVRTLESMGVRARPITSSVFMADYLDKEKWKFVGKITDINKDPIESAIESGYLPILTSMAETTEGQVLNVNADVAAGELARILEPLKVVYLSEKGGLFGGEGNKISAINLDEEFDHLMSQSWCKFGTRLKIKEIKELLDSLPRTSSVAIIHPAELQKELFTDSGAGTLIRRGNKLMTAESVSEFSDLQKLKDVLIRDRDLTDSRATVDRYVEFLKERKFKAFFDEPMKALAVVLQPSETQNYGILATLTITKSGWLTNVADNLFSAIKKEYPSLVWTVKADDENLSWFFEKADGHIVRGNDVLFWYGIEEGQGLMDLMKEFTNHGRAMLGESNLEARLHRAAQVASQNLKAQFASGSAANQARGYSTFARRPVMGTAGALYKGQARGYATTTNPNPLTAESMPPTSLLNTHPNFILKHVSSRELAGQKLQGYNKKEIIYENLSAEDVKQMEENGEIDVWVMALPNGVCKPYVDAINEAREKTPREDGSLIVDLSADYRFDNSWTYGLPELIRRSAIAQATRISNPGCYATAAQLGIAPLVEHLGGQPTVFGVSGYSGAGTKPSPKNNVEFLTNNLVPYSLTDHIHEREISNQLGTAVGFVPHVAVWFQGIHHTINIPLNKTMTSRDIRQIYQDRYAGEKLVKVVGERRWSSRSAESTVSRSVALPSTVRASELLFVLPLTICSKGAATQCLQNMNLARGYAEYEGIPLMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ15</accession>
    <name>A0ABR1VJ15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665038.1">
        <property type="nucleotide sequence ID" value="XM_066815748.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048808"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="125" mass="13734" checksum="CB344ADB4DDC0769" modified="2025-10-08" version="1">MFQKIFANALRLKALLLQTGQRYRADFVPTGARFNPDIMSLIGLENMGLWQQNQGLAGRGPNAPDPPRAARLCVFPAIHAYPRETEWSPGTDASTFTVDYCNCVNVDASTDGTRLVSKAVVSVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKW1</accession>
    <name>A0ABR1VKW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 NT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664749.1">
        <property type="nucleotide sequence ID" value="XM_066815459.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048519"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039931">
        <property type="entry name" value="EEIG1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019448">
        <property type="entry name" value="NT-C2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456:SF1">
        <property type="entry name" value="C2 NT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456">
        <property type="entry name" value="FAMILY WITH SEQUENCE SIMILARITY 102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10358">
        <property type="entry name" value="NT-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51840">
        <property type="entry name" value="C2_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 NT-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="536" mass="57922" checksum="DE8CAE9DEF747E0F" modified="2025-10-08" version="1">MPSLLPILVNKARKPKFELHLTIYDLNNVPLVSGTSQIKWSLPHSMHSDHRSRTSKCPIDSVNHRVSYNYSKVVPLRITIDRNNILTECPIEFEVAQEFPSGEYVEESENFPRRSISSAPGGTPGGGRARARSSLENAREKILGPALNGRPGSGHGSGPPGSPKSTMSQGAATTSSSEGPIVEEDVAEEGIVRRYLMQDSKINSTLKIGILMVQLDGDRNYVAPALKTAPMFGGIAGIMASGESTVDAARDDPSQSKTTTQNPSSSLKARDTSELQDMYRRALAASWACQPGELPADECVEDIFGGGDGWKNPASPHRSRETNSRSKSRIPDDASSSRSSGSEEVHHGTLRPSDLRRLRKYMHHRHHSGASEKSGLSTVIGSPPLTGTTENDINIGNSNNNNNLRPSGSTHSSRSHKGRSVSRHRPATGHSSHRRQHSRESGHNAPFSLDAAVNSGNGVLGPAVLIEETNSNNASHGRRESLTSLAPTLGSISTERDSRGNQQDRGREGFRRPREVDEFEIRSDLVSWALPGASVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKW6</accession>
    <name>A0ABR1VKW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MAGE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664673.1">
        <property type="nucleotide sequence ID" value="XM_066815383.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048443"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1200">
        <property type="entry name" value="MAGE homology domain, winged helix WH1 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1210">
        <property type="entry name" value="MAGE homology domain, winged helix WH2 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037445">
        <property type="entry name" value="MAGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041898">
        <property type="entry name" value="MAGE_WH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041899">
        <property type="entry name" value="MAGE_WH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002190">
        <property type="entry name" value="MHD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736">
        <property type="entry name" value="MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736:SF14">
        <property type="entry name" value="NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01454">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01373">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50838">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAGE" evidence="2">
        <location>
            <begin position="48"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="288" mass="32432" checksum="9F4CA69BDC0074A7" modified="2025-10-08" version="1">MPTQTQRRRRDDDDEPRRRSRRQVESDAEEASSQDEDGDVSMGGAGDEAQLIKKLVRYALACEHARIPIKRDGIREKVLGSNSRSFKSIFDGAQLQLRQVFGMEMEELPVKEKRTLKEKQKATARKTNGATSSRQYVLVTTIPSQYRTPEIIAPSRAPSSREEAEYVGFYSFVISVITLSGGELSDMKLRRYLTRMNASQNLPMDRTDNVLAKLVRQGYLDKVVEKSDHGEEDTVTWCVGSRGRVEVPPDSIAGIIRLVWGEEKPDDLEKKISRSLGLQQPDDDAGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT53</accession>
    <name>A0ABR1VT53_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665386.1">
        <property type="nucleotide sequence ID" value="XM_066813424.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046484"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="268" mass="29910" checksum="F9CBE26137687F29" modified="2025-10-08" version="1">MSFFWRSPPPKAAVEIGEGCKPGTAARGTDLYIIEREIRDKLDEEPDFDSLKEMKAYIESMDFLKKDGTTVNVYFVDECMKHHCRRRVAGSVASGASRTTASDVGSISPSTRHTISSSADNSTAAELQQHLIPFQLMTTDRRWRFVIARKTTSGTQNYMSTKIAGQCGFSREPGASIDIKLELLREQLDCSVHVREMEQDMLLTEALVVRFSSYRADYQLDDYFHESTVTSCRLRAARLVACSLSPVQKLTAVHSVNGDRAAPDIQGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTM6</accession>
    <name>A0ABR1VTM6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lovastatin diketide synthase LovF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009267</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665544.1">
        <property type="nucleotide sequence ID" value="XM_066813582.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046642"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF50">
        <property type="entry name" value="HIGHLY REDUCING POLYKETIDE SYNTHASE SRDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="254"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="594"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8074604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="857" mass="92767" checksum="E2B6FB76ADD2E097" modified="2025-10-08" version="1">MSVIVSTKVSGSAEDGISSARSIAEVISPITPSTNGVVHLLLGTDGDQPPLLKTVADEFEHRGVTTKVIHLEDVLETVPAGARVVAFLSTRDNLLLADEQRLKAFQYLAKTVESMVWLTSSGVVKGRNAVAGFMIGLMRTIATENPASRFMSIDIDAENFEITDGDIDERFDLVSCIVDQEIALYSESSSAGDENRVKDRELAWQDGCMWVSRVVPDAGLGAYAEPNKTPSCSGYDRVSLGKLGPVRAAFETPGVLNSLYFRTYTDMLQPIPADHIEVRVRAVGLNWKDLGLSSGRFDADGSNLSSEYAGTVTRIGADVDTVAVGDRVYGIGRGHFGNYTCVPAAFAQKLRPTDKSAEMATMPLVFATAVYAFQYVARIRKGMKVLIQSATGGLGLAAIQVAQSKGAEIYATVSSDEKIKFLVDAVGIDADHIFSSRDPKALVRAAKACCSKGGFDVILSTAVGSDTLNQSLKALAPMGHLVDVGRMDVLESKDLGLELFQKNANFSSFDLNLVLDNDPELGGELMEAVNDLYQVGFITPIQPITVSDIADLDKTLMGFSKGLHIGKLVVSFQNPKSQIKVVREPKSVTFKADARFVVTGGMGGLGRGIIRWMVDRGARDFLVLSRRGVTTPEAHLLVKDLEARGVIIESVECDVSNRDDSLRANRSGGVVHAAISQSDLPFDRLNIDQWQDGFAAKALGTLNLHEATTSLPLDFFVMVTSTEDYFARYRRNLSLPASTVSYGLVADVDSDFRDTAAKTKDIYVRNKAMVISEHQVLAQLEPAFLYSVPYKTVASDWIGKQQDPLSAANLYTCMDPAALAATAARSADTDAPRWYSDGRVSLVMRAMQDAQKLQQQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTV9</accession>
    <name>A0ABR1VTV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glucose transporter rco-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_009357</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665634.1">
        <property type="nucleotide sequence ID" value="XM_066813672.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046732"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF40">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="23"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="519"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="530"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8074694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="576" mass="61949" checksum="74C9F508898164BA" modified="2025-10-08" version="1">MAIAMGWQKPDNVAGSSAPAIMIGLFVATGGLLFGYDTGTINGILVMKSFVQQFNNGYLDAQHDNLPAISPPNIAIIVAILSVGTFIGSLLAAPAADKIGRRISLLIAVGVFCFGVIFQVCADAIPMLLVGRLFAGVGVGAVSLLVPLYQSEMAPKWIRGTLVCAYQLSITLGLLGASIVNIGTQTINGAAAYRIPMGLQLTWACVLVVGIMVLPETPRYLIKCGKNEAAALSLSRLRRLDITHPALVEELAEIQANHDYELTLGPDSYRDILLGAPHLGRRTLTGCGLQMLQQLTGINFIMYYGTSFFHGAGIDSPFLIALITNVVNVISTIPGLFVVETWGRRNLLLVGAVGMSLCQMVIAIYSSAVGSPSTNEVSTFSSKILIVFVMFFVFFYAASWGPVCWVVTAEIYPLKVRAKAMSITTASNWLLNFGIAYGTPYIIGSGAGYADLGPKVFYVWGAFCVLAGVFVYCMVYETSKISLEQIDEMYERVAHAWNSKGFEPSWSFQQLRDEGFADSGIPPTEHELQPSVTGSSTADSISTEQTNETDTSTNGNMTQQDKAIQQMGLGNVDFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTW7</accession>
    <name>A0ABR1VTW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">acetyl-CoA C-acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009363</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665640.1">
        <property type="nucleotide sequence ID" value="XM_066813678.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046738"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF165">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase C-terminal" evidence="5">
        <location>
            <begin position="12"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8074700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="135" mass="13901" checksum="593AFBB8A662098E" modified="2025-10-08" version="1">MSEAKVKELGIKPIAKILGWADAAQEPERFTTAPALAIPKAIKHAGLTDKDVEYYEINEAFSVVALANMKLLGLSADKVNVFGGSVAIGHPLGGSGARIVTTLTTVLREKKAKIGCAGICNGGGGASAIVIESLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTY3</accession>
    <name>A0ABR1VTY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF1772-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009376</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the anthrone oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665653.1">
        <property type="nucleotide sequence ID" value="XM_066813691.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046751"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013901">
        <property type="entry name" value="Anthrone_oxy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042">
        <property type="entry name" value="ANTHRONE OXYGENASE ENCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042:SF3">
        <property type="entry name" value="ANTHRONE OXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08592">
        <property type="entry name" value="Anthrone_oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8074713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="17484" checksum="1CE4D79F38E0AC71" modified="2025-10-08" version="1">MQTSSTSETLIASTNILSSAVIAGATASLSAFAVPAVLNTGASTDVMLRQWFSIFHRGKLIPIAAVATGLSHVAVSYGRWAAGRQWRGFALGGALTAALIPFTLALVMPTNRVLAAAEAHGSSSKESRMSDDKVRQLIRSWRDRNAIRCFLPLAGAAFALWNLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU72</accession>
    <name>A0ABR1VU72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ClpP/crotonase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009467</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665744.1">
        <property type="nucleotide sequence ID" value="XM_066813782.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046842"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF4">
        <property type="entry name" value="ENOYL-COA HYDRATASE_ISOMERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G01890)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="325" mass="34923" checksum="277604A1BA4DC457" modified="2025-10-08" version="1">MTTRSPQIRLSHHPASAPVPTPVILVILNRPEANNAFTDTMVTSLVTAFDLLSTDPRVKAIVFTGGDPQNRIFCPGMDLDGASKSTSSPSPSSSPLGPEDLARQREAHRDGGAQVSLAIHRCQKPVVAALNGHAVGVGITMTLACAARVTHAGAKIGFVFARRGINMEGCSSFFLPRILGPGRALTLVTTGATYAAPDPAVRDLFAAVLDEPADVLPRALGLAEEVAGRTSAVATKAMRDMLYHGPATPEEAERLESRVFFDLFRGADAREGIRSFLEKREPRFEARWETDKPAVWPWWKGKKTVVSETTAEDSGGLMGWLKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVF4</accession>
    <name>A0ABR1VVF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_009888</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. GCN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666165.1">
        <property type="nucleotide sequence ID" value="XM_066814203.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047263"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05509">
        <property type="entry name" value="Bromo_gcn5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037800">
        <property type="entry name" value="GCN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750">
        <property type="entry name" value="GH11602P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750:SF3">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 12" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="60"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="14">
        <location>
            <begin position="302"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8075225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="397" mass="45723" checksum="29F469AAEAF78790" modified="2025-10-08" version="1">MVKDENGKRKASDEPSSPTANKKTKLSDEPSEPDKAKEPAMKPIPFPEKPAVIEEREGDIEFRVVNNDNKRESLIILTGLKCIFQKQLPKMPKDYIARLVYDRTHLSIAIVKKPLEVVGGITYRPFKGRQFAEIVFCAISSDQQVKGYGAHLMSHLKDYVKATSDVMHFLTYADNYAIGYFKKQGFTKEITLPKSVWMGYIKDYEGGTIMQCSMLPRVRYLEMGRMLLKQKECVHAKIRAFSKSHVIHQPPKEWKSGVTSIDPLSISAIRESGWSPDMDELARQPRHGPNYNQLLHLLNDLQNHQSAWPFLMPVNKDDVADYYDVIKEPMDLSTMEAKLEADQYETPEAFIKDARLVFDNCRKYNNETTPYAKSANKLERYMWQQIKAIPEWSHLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWA4</accession>
    <name>A0ABR1VWA4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleoporin nup44</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009113</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665390.1">
        <property type="nucleotide sequence ID" value="XM_066813428.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046488"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.3600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.490">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024864">
        <property type="entry name" value="Nup54/Nup57/Nup44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025712">
        <property type="entry name" value="Nup54_alpha-helical_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13000">
        <property type="entry name" value="NUCLEOPORIN P54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13000:SF0">
        <property type="entry name" value="NUCLEOPORIN P54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13874">
        <property type="entry name" value="Nup54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18570">
        <property type="entry name" value="Nup54_57_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup54 alpha-helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="345"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="9"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8074450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="391" mass="44029" checksum="D6E2ED61C5F045B0" modified="2025-10-08" version="1">MSLFATKPAGATGFGQQQGTSSIFGQPAASTTTPAAGSSIFGQPQGQQQQQQQQPQQSTNAFGTSSLFGQPQQQQQQQQPSFGASNPFQPLTEQQQQAYHQHFQQQQQQQQQQSQQQPQLGASTQNFRTSLWQPGQDSTHQKPITEQCVAIFQKWNPTSSDTVFKHYFYNKVDEAQVPFYQPGPNEDPREWEQAVRDKPGPGYVPVLATGFVHMAERLKTQRYNLSQLNNALHQINASLDAILSKHDLETSVRALNAKRKHALLRQRCIAIATKVQVLRNRGYALDTDEDELKSKLEALDRGLADPSLSARNEELWSRLIMLRNHADTLRDEINQRGGLSGDGISEEAEARAKKLLEDYDKQLQALKGMVEKVKEDYDEWEQERNPASDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWH9</accession>
    <name>A0ABR1VWH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010278</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666555.1">
        <property type="nucleotide sequence ID" value="XM_066814593.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047653"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF9">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORT PROTEIN (AFU_ORTHOLOGUE AFUA_2G09450)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="80"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="506"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="529" mass="57863" checksum="B8E19D28B660EA55" modified="2025-10-08" version="1">MPASHSSKAYRGGRRPHEPAVVVKGTWATAKQSFRDLFRWQQRVVITNSQGETYEEWQNPPPLQNPFKLFALLSAKQWLYFFVGFYAWTADAFDFHALSIQTTKLAKYYGRSKTDITTAITLTLLLRSVGAAIFGLLGDRFGRKWPMIGNMIILVGLLQIATIYSTTFQQFLAVRSLFGLFMGGVYGNAVAMALENCPTDARGLMSGIMQQGYSFGYVLAACANLGVGGATETWKTVFWIAAGLSIGAGLIRLCFPESKQFLEAKKSGHKITAGDFWGETKSMLAREWRMCLYCVVLMTWFNYYSHTSQDSYTTFMITAKELDSAAGTRASIWMKVGACVGGTVVGYLSQFVGRRRAIVVAALVSCCMIPGWILPEGERSLSASGFFMQFFVQGAWGVIPIHLNELSPPAYRSSFPGITYQLGNMISSPSAQIVNAIAESHFVTSRKGNRVEAYGPVMGIATVIIALGIAITTALGPEKLGRHFEEAGPAGAHSSDANAHLQEKTADVLSLAESKQGQHSTANEVEHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWW3</accession>
    <name>A0ABR1VWW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Anaphase-promoting complex subunit 4-like WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010413</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666690.1">
        <property type="nucleotide sequence ID" value="XM_066814728.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047788"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032847">
        <property type="entry name" value="PRPF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="263"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="349"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="3">
        <location>
            <begin position="429"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="482"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="515" mass="57783" checksum="A1007B4836B29CF3" modified="2025-10-08" version="1">MANFGEYPPNMASQDALIVREQTGPEHAVVPYSGEELSRQQLGPANPYFDPSTRKRKNNHRAVERAGGPDREYQTGAEVKAEAKRIREGREGKGNATIADGDGAYVGPWARYKRPEFEDVEIAEGEEVGSDEEVVYVTDEDEDVIESGTVVSAPTVALQRRKEVEALGEESTVFHGEAEFDYQGRSYMHVPQDLDVDLRKEPGSVTNYIPKKLIHTWKNNFNDKAVTALRFFPGSGHLLLAAGADSTVKIFDVYHQRELLRSYHGHGKAVSDICFNNSGNEFISSGYDRFIKLWDTETGVCKAKFTTGKTPHVVKFNPSYEHAHEFVAGMSDNKIVQWDTRTKEIVQEYDHHLAAINTITFVDEGRRFMTTADDKSLRVWDYSIPVPIKYHASEEQFALTRASPHPSGKYVAYQSGNNEIQVFSAQDKFRRNSKKLFKGHNSAGSAIDLNISPDGQFLASGDTAGFLCFWDWKTCKMYHKIPASQNGSISCVQWHPQETSRVVAAGQDGVIRYYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W0U0</accession>
    <name>A0ABR1W0U0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666739.1">
        <property type="nucleotide sequence ID" value="XM_066814777.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047837"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="257" mass="28492" checksum="FA3A83E297B98570" modified="2025-10-08" version="1">MSTKRKPDASNTISSDQTAASDFERQRLFILHDPLLTGQNPKADEQPVRTGRQTPPLSVPTSLPDWTTREDTRTESDDSISLDEEYVGEVRDVPHLSGMDDVAHEIGSPGDEGLSVALQPTAKDPSLKNRIHELELELARLRKSLSGENNKPPTFQTFHLLEGDPTRFLAEPSWRVDGANTYLKGNVPLSEPYIYLQELGNIAFVVYKEYASDSSPDAILSEVAHEKAKSLANPKPVSHFIELYSPPHEGGSECFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7A1</accession>
    <name>A0ABR1W7A1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007182</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666839.1">
        <property type="nucleotide sequence ID" value="XM_066811497.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044557"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051704">
        <property type="entry name" value="FAD_aromatic-hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865:SF7">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865">
        <property type="entry name" value="OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="5"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8079364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="359" mass="38168" checksum="F4C064681A236166" modified="2025-10-08" version="1">MLQPKVLVVGASIAGPMAAYWLAKAGAQVTVVERFPHLRTNGQNIDIRTVGVTVMRRIPGMEEAVRAKVLPMKGIGFVDTNGRRYGTISATGNPDQQSLVSEYEILRGDLSKVLFDLTKDNKHISYVFGEQAASMKWHHDSKGGSNGEQITVGFMNGHPTTTFDLVVACDGATSRTRAMGLGCGIRDYVQSTNAWAAYYSTPPGQDLLKGASGGIGHGYNAVGGRMLGIDAPDAATGSNRLTFMHGGVQEQKATQPFREAVQKDDEALRNFVSEQLTGAGWICDEAAGLIANADDFYASELVQVKLPSLYKGRFVLVGDAGYAPGPTGTGTSLAMAGAYVLAGEIHRHRGDLGGWTKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7S7</accession>
    <name>A0ABR1W7S7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Taurine catabolism dioxygenase TauD- TfdA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007362</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667019.1">
        <property type="nucleotide sequence ID" value="XM_066811677.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044737"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF9">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT TAURINE DIOXYGENASE (AFU_ORTHOLOGUE AFUA_3G01010)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="72"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="360" mass="40248" checksum="E45F01EAD0D93992" modified="2025-10-08" version="1">MAPAPIADHIVDVAPPIKDTLGLPETTLARFKKGGVDLSNGYPYRPSRPLYLQDVLKIRNEPWEHKDAGARADKSKSALLSAATKKDELALLIAERSVVFFRNQDISPHQQLELGKYYGVPEVHPQVPQVPGELGVSVIWPDLMATERKADFRNPGGASRWHTDLVHELQPAGITHLHNDAVPPVGGDTLWASGYAAYEKLSPGFRQIIDGKSAVYRSAHPYLDRERPEAGPRWVERVHPLVRVHPATGWKSLFVNRAMTDRIVGLDRGESDAILNYLYDVYEKNVDIQLRFKWTPGTSALWDNRITIHNASWDYGGKYPRHGTRVTALAEKPYFEPNAPTRRQALGLLDEGELLEDGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7X8</accession>
    <name>A0ABR1W7X8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MIF4G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007330</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666987.1">
        <property type="nucleotide sequence ID" value="XM_066811645.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044705"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.80.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039762">
        <property type="entry name" value="Nmd2/UPF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007193">
        <property type="entry name" value="Upf2/Nmd2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839:SF7">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04050">
        <property type="entry name" value="Upf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G" evidence="4">
        <location>
            <begin position="643"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="257"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="873"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="982"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1070"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="883"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1094"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1168"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1179"/>
            <end position="1190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1190" mass="134036" checksum="5BB26C80001919D5" modified="2025-10-08" version="1">MDRPRKRESASAELGKTLWELRSLNERAWNGDTDVFPVGKSLDSSLKKNSGFIRRLRTAISAATLDTFLQEIKTLSLHKYLSEVISACYEGLCRLKSPGEVEAGVEIVSALHQRFGPAEFTEYLGWLLGKGMSTPDKGLLKLLAPEAREKEEKERLVRQRALLRVVTELWLVDVLRTLDDVKRNDAAHGATGKDAGLKPKVSATSKGGAAEPFPLEVLKDLLGHDREHANLPLLVIFVKAFSWDILGFKSAVSDGRKTVEEDGATKSAEEPAEPTNSDDGSFDCASDDPAFTTPELQERFRNILKRYFDDVKAHILRDQKSIAAQRGRNSEAYVKSGEVFEDRQANFERQLKAQERLISNAQIIAEAIGAEMPDLKDSGDSSAATNGSIGLVKTGEYLRGQSDGAGIWQDEDERRFYENLVDLKGKVPNILLEDGKKKKADADDQVGKKAEVAEASETSKVQDVNDDQSTAIANKTIGAQVDALLTRLPEFTSKDVVDETAIDFCFLNSKASRNRLIKALTEVPKGRTDLLPFWSRLVATLGQYMPDVPKGVVEYLDAEFRSLQRRKEKDFLGQVRLSNIRYLAELTKFGIVPEHVVFHCLKRKKSVQHIGQAERMLIENAIYYVDPPERAAIQQKERTPTEVFIRKLIYVDMTKRNYTKILKQIRRLHWEEPEVVEILAKVFSKPAKVKYGSIHILAILLSAIYRYHPEFVISVMDTVIESVDNGLEQNDFKYNQRRIAEVKYLGELYNYRMLDHPVIFETLYRVMTFGHGGVPLPGRLNPFDLPDDYFRIRLAATILETCGMFFNRGAAGKKLDYFLSFLQYYIFTKAPLPMDIEFIVQDTFSLTRPQWKLATTPEEASKAFQLAILQDQKNAGHEKAVDPEPEDAESDISSDDDGGEGDDDLAQDADKDEESNSEEEDDLDDGEPPQSPRDTESEDEAIIVTRKAEEVDPEDEADFEREYAKMMAESLESRKFERKPLFDAPVPVRPKTREAAAANEPEEGDNEGPSLNKMAFSLLTKKGNRQQTRMVELPSDSNFAVAMKNQQQAEREEQQRIKNLVLNLDLRETEEADGDTNSNPLLPNANLIHTTRGAGHDKTSVYHLNRPEKPSKERGGQRVRRLQMNDLDWYDSTQDKNQKRPGITPGPTGLATRDANAGMASPSIPVDTNKRRVPDGVRQHRRGRANRART</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8Y3</accession>
    <name>A0ABR1W8Y3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mutator-like element</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667440.1">
        <property type="nucleotide sequence ID" value="XM_066812098.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045158"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47482:SF5">
        <property type="entry name" value="FAR1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47482">
        <property type="entry name" value="OS11G0632001 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="562"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="137"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="637" mass="72426" checksum="0EE99FE6519A4D5D" modified="2025-10-08" version="1">MSTANDHNPHSHPGLAFPQVNGLRRTYTSSSHSATPPKPSPTPQQHQSPYQPQQYTPQQPPQAHYPHNLFTSSTPSPVPGVNGVQNVPNGASRHTPPRHTARLPWPPAANALAMNQPMPQQVQQHVQQPVPQPVQPVQPLQQQPHQAHQNHQTHQAHQAHQAHQTHQTHQAHQNHQNHQTHQTHQGHPVAQQVQPLPQQQPVQQQPQPVHQPNDANLMFIHSPIAKACLRRIRRITSRATRRAIHRVINRVTRRATRKITNRVTRHVLRPTPSRRIRQVTNLRLSNRLHRHIKITSRFHHKHTNHLRHYSRSRHRNHQPTVQQQESHNDDDMDMDSQDESGEGDSHLSPKLIEGTPFVPRTPMGGMMSAPPEGGSYASLEAVHRHVLEYCTSVGYAVVIGRSKKTVPGLKKVLFVCDRAGKPPSRVSPEQRKRKTSSRKCNCQFGFFAIEQRTQWTIRYRPDEVHLQHNHGPSESPLLHPAARKLDSKMVAAVKQLKESGIGVSQTLEILQQQNPHVPLLPRDIYNARAAINRNPQKVEAGIAEERPAIYSKPAPTPEERIRSDLRRELANTKEELKKLREESKKTIEKLQEDLRTKDKTIEKFEMFIDICNQRVMLQREKLADNGGNNTANGGANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA51</accession>
    <name>A0ABR1WA51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WAS/WASL-interacting protein family member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007204</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666861.1">
        <property type="nucleotide sequence ID" value="XM_066811519.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044579"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="11"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="291"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="639" mass="69615" checksum="B36C27B325BD19E5" modified="2025-10-08" version="1">MVFFGSHNRRVCGFHYLHGQNPTYLPQVKVEAQTSIISSIARTTLIQTFVNPATHAIPQLYYTFPLFDGVSIVDFTCTVGDRVIKGIVKEKAQAKATFDHAVAQGQTAGLLEQAVDTAGDVFKTSVGNVPGGAQIKVEISCLGELKHDAQNNGLRLTIPTTIAPRYGSYPGSLQTPHAASATTHGGMKITVDAQVSSGSRITSIQSPSHQIAVTTGRTSTASDQEELSFEKASATLSLGTAELDKDFVLQMTATEIGNPVAILEEHPSMPDQKAIMATLVPKFELAPEKPEVVFVCDRSGSMSDKIIDLKKALQLFVKSLAVGIKFNICSFGSCHSFLWDRSRTYDSASMAEAMQHIESFSANYGGTEMYAPIEQTITRRYQDMNLEVFLLTDGEIWDQDRLVHLINEGVAASDGAIRFFTLGIGPSVSHSLIERVARAGNGFAQAIGNSEEMGSKVVRMLKGAMFPHIKDYTMEVKYEADQDEDFEVIETLEESLVVPIPETKETQEETASPKKPISLFDPSVNDAAPVVVTSGINTGAVEKFSAIPPISVPKLLQAPHLIPPLFPFTRSTIYLLLSSETRTPKSVVLRGTSRQGPLKLEIPVSPPRRERQKHPSAGRQEGRRRARGGPRLDLSRQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAN3</accession>
    <name>A0ABR1WAN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008382</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668039.1">
        <property type="nucleotide sequence ID" value="XM_066812697.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045757"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="49389" checksum="C453BAC6449E487E" modified="2025-10-08" version="1">MSKENPHLQMKKWAEEYGPVFSLMLGTSTTIVLSSDRAVKELLDKRGSVYNSRPDLYIARTHGERWRAIHKLFHVILNVRAATAYVPYQDLEAKRLMCGLLDEPDLWVDHVRRFTTSLVTQMVYGVRTASIYDPKLRRLYDVIDEFVPTVGSTESALLDFYPILRELPDALLPSKRKAKVQHANERALFLDHWTECKRRINEKTSMVRPPCFGIDVFNAQKSGEFSNDEAAYVASTILEAGYDTTANTVMGFMQAMMLYPEAQQTAQEELDRVCGGRMPTMDDVPNLPYIRAIVKETLRWMPTAILGVPHCAMRDDDYMGYKIPKNASVVTNVWGIHRDPKRYAHPDVFDPTRYLGDDQTAAEAAANPDVSKRDHFVFGTSRILWGLRIQKAIAPDGSEITPDPSKLSKGFLVHPEAFPQWKAVPEGMNFSAVAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB58</accession>
    <name>A0ABR1WB58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007518</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667175.1">
        <property type="nucleotide sequence ID" value="XM_066811833.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044893"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="403"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="828" mass="94127" checksum="86CA52872028A2B2" modified="2025-10-08" version="1">MESRGRAYDIWSIGCILLEYLVWATSGYDALRTFKNHTEFFWAQTMAPGQPQYTVHPYVGSYMQMTEQRLEENTAHKEILLLVRDSLLVLKDRRIRARDLSQGLETIRTKCYESPQSYPVPTQFKYPENELGSAYRPPHIPQTNEGMLAAPGQGGSHLRPQLDKRKPEDDSPMTLIVPKVKFDSGSGASMASENNQQSKSLNDSWKSSPDNKLASDFLSKVGWDRVKPVEPGNTPLLCSSCHAIKPSRLFERNCDLYAVQSKSEFCDLCSMLWHAVLETGARMPRWVIFQQDDGLIRIENGPVLLSLYSEPGDIPTRRYPTACTDLAHPGSALTQQARLGLPQLLRAGSAEQFTLLRQWTQACDSTHVMCRRHTDTSSSMPTRLLDVDSLKLVESASINPGRYVALSHCWGKLQDIQKFSATKANVESLKQQIALGQLPQNFRDAVMVTRGLGIMYLWIDSLCIIQDEEADWYWESARMEQVFSNAYCTIAASASRSSIEGFLGDRPARRCVQLQLPNEGTLYACLAIEDFNRDVERAPLSLRGWVLQERALSRRSIFFTSTQVYWECGSAVYCETLSKLQNTKSRFIGDANFPNFAMEYYRDGRQVLVQDLYERYSGLQFITMPTDRAIAILGLQERLARAFRTKAAYGMFSVYFARGLLWRRASVEPMTRIAWPPAHYVPTWSWLSKLGPIKYLPLEFEKVEWSLDDGFENPLKWLGKSRRVGVGPWDKTKPRDEVVLHGSVRKLLTLKGDHMRVKFDTEESDGLEGLHCMVVGRDKAGTFEDEAKHYVLVVYPLEGVNNGTFGRVGIATLRECHLGYEKRWVNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBC7</accession>
    <name>A0ABR1WBC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668278.1">
        <property type="nucleotide sequence ID" value="XM_066812936.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045996"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="87" mass="9373" checksum="8263B223A49A7730" modified="2025-10-08" version="1">MWGGGASGTSSPARSRSTSSSFFQPTPRDRSSSLRKSLNAAEIFNLGNNSSSSVYERVPREDDEEDRLHENTSLLADGPGDRATGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBP9</accession>
    <name>A0ABR1WBP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668322.1">
        <property type="nucleotide sequence ID" value="XM_066812980.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046040"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF8">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="399" mass="44371" checksum="8D5E9FB2AA454735" modified="2025-10-08" version="1">MTKLRSISIQPDGKTALFQGGAYDGQANQYLWDNGYVGTTGACDCVGMMGPGLGGGHGRMEGSYGLIADNLVNINAVLADGSEVVVNDTSNADLFWAMRGAGHNFAAVTSFEMKIYPKGLDTWHYHNYYWTQDKLEAVFEAMNKFHDHGKTPVKMGVNYGGFWWNANVSDTEPSMYWVFGYAGAAEEAEELLEPFNAIPAAASDQGDVPYPQIASRQGTGVNETLCAPSRKHIFSTAGLIEYNITIEREIYHTFAQMVERYPDLKTTHIVHEGYSTEAVQKVPSDSTAYPLRNDTLLMFFDAVIPDNGRITRVTKKWAAEVRGLWNAGQPQRKPSTYVNYAAGDESLESMYGYEPWRLSRLRSLKAKFDPHNRFRYYNPIIRDGGHPGSYGPLVNATQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBR7</accession>
    <name>A0ABR1WBR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667385.1">
        <property type="nucleotide sequence ID" value="XM_066812043.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045103"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="597" mass="67075" checksum="B6927DA0951A2945" modified="2025-10-08" version="1">MFSPHPIVYTSPSAGSGTGSGSAPIAVSQDDEHELPSLGSPLPGRYGVILKGGMSTVVVDLVQSPPKNREIEKEHGQQSDAPSSLEPGAPRRSYLAAFPAFVSFADRSWLLPPKGPDDEIWFMEPGELRKRNLSKLQATPGLYKVILDGPPRDVEMEAGIIADFIKHKEALRLRLRDGFFGDKRWHDMVKEYYQWQSQLAFLDLDQRKAAIAHILPDIRIRMKAAFTSYQNADVAIGAELAGIQLSTFSTSPPKPLVPDSQEKKTQWAWDMTSYSHSISNRVLTPVERRRLEVGPEVLPPEPAVSFTPPELSHAGDQSSSAINLPRMFDMTLDHTDDWSPHDRRKFYKTYGYNAAQLYLKYFKSSPDQRCAEVDVPEWFHIFEAQSKVFISHGGTAHSRFIDLNFLLGSLATKVRDEKARVHALERQDDGQSSGSRNEYHKPHPHWSTAARRRNGGWWRCRSDDDAPLSERRCRLCHGNKPSSTSFTLNEGHATQAKFDLLMETIQAAQRVVAKRDRHVVENRMRAEAQAARQAQTSSASSSHAHGGAVERVRAEFYAECAARDRLHRRPPGSTADEERTEAAKRLDARRSRLSAHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBV8</accession>
    <name>A0ABR1WBV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667098.1">
        <property type="nucleotide sequence ID" value="XM_066811756.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044816"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="793"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="793"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="929" mass="103691" checksum="D8774067288EADC5" modified="2025-10-08" version="1">MLTNIVSQTSPGAGSLYVRASSSNVLAPLSTSVLLNGRHQQTRSYRCGIWSSYFGPDFQRHARRRQRMIMYKYAETQNRRSSWDQNPLAEDAKTALRRVIGKYWHAGTSICGSRMVSYGTKPSQANEEGNQKDGTQTTESTTSSTWTSPLGDVIHRWTKQTSPGVKRAGSGRGSSTTEGSSTGTSLEAEFIIDPITNRKVIRKTYGATTSNTESPTGTSKSYRFRHTPFAPNGLGPEHVSPPIYQDGTPSREELRRIRREVYDDLHKYNPAEPDEIKDISTEAATPKYDDLHDYKPTEHDEIRNPSEEATQTYDDLDKYNPTEHDEIKYEPEQPVQKYDDLNDYRPMQPDEIAVSWSEPKYDDLGDYKPFRYKESDATQPETKPDYDDLHKYRPYMHNEDAVSDDAAAPKYEDLDKYQSHTDQVDNNVDSAKPQYEDLDKYQPFLHQEGQSETKQGSQYEDLDKYRSDVFKEVEVAEEGEPFEQYGDLDQYKAAYRYQEPDGKAPETQDVIEKSLGEFDADKENRENLEQAMTGYIAVSDAIDREVSASLQRSRRRAMEDQPSVNIFRDPPEKFHELLKEHGLGPASDEARQVDIQSAEKDYSDIQSAEKDYSDNLTCHFNSNVEPALGRMNAAATGQPAERPSKSPVSRRQQTEADTDPSSEVLESLGTPTEDGRDAAAQTHKKTKYGDMNPETPVTLPPRSPPPTSPPDAAAPAIYKILAYDPTMQNVSIAETTSIVPDQAAPLTPSEVLVRLSNPTKFFPHFEPLRAEGFEIVSGSGDVLVFRKVHEPSASSAATDSSSSSSLESNSTAPNPVNPIDMMGRNPLPNAAAFASPTGFVNYNDSFVEARQQRRSPPFRSNIDVRREEPVFSGPKVYADRSLKKKKKKAGLTKRIFVGGVWVAGVSYALGVIGEYFATGGIDGKGPAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCK8</accession>
    <name>A0ABR1WCK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15">DNA topoisomerase 2</fullName>
            <ecNumber evidence="5 15">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_007712</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14 15">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5 15"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667369.1">
        <property type="nucleotide sequence ID" value="XM_066812027.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045087"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16930">
        <property type="entry name" value="HATPase_TopII-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03481">
        <property type="entry name" value="TopoIIA_Trans_ScTopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03365">
        <property type="entry name" value="TOPRIM_TopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050634">
        <property type="entry name" value="DNA_Topoisomerase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001154">
        <property type="entry name" value="TopoII_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031660">
        <property type="entry name" value="TOPRIM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034157">
        <property type="entry name" value="TOPRIM_TopoII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169:SF38">
        <property type="entry name" value="DNA TOPOISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169">
        <property type="entry name" value="DNA TOPOISOMERASE/GYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16898">
        <property type="entry name" value="TOPRIM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01158">
        <property type="entry name" value="TOPISMRASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13 14 15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14 15" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="17">
        <location>
            <begin position="558"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="18">
        <location>
            <begin position="811"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1187"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1299"/>
            <end position="1690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1199"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1360"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1415"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1541"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1580"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1599"/>
            <end position="1612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1613"/>
            <end position="1624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1635"/>
            <end position="1645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1655"/>
            <end position="1690"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="14">
        <location>
            <position position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8079894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1690" mass="188938" checksum="97E84B3506948D32" modified="2025-10-08" version="1">MDSDIMDDSVFDENESDGFSPEPKPKAKAKPAPKKAAAKPAAPKKMVQTTLKTAKAAPKKRAKPTSDDEEDAADNSDFSNTPPNAKKQKKAPAAKKASSKPLEEIENDSMMFDGSPDAKPAKKKTATETYQKLTQLEHIIKRPDTYIGSVERTEQPMWVFDKETKQMKWDKVGFVPGLYKIFDEIIVNAADNKQRDPKGMTYLKVTVNRAEGIITVENNGKGIPVEKHEKEKVYIPELVFGHLLAGSNFDDDEKKTVGGRNGYGAKLCNVFSTEFTLECQDSKNGKRYKQTWRNNMGTMDPAKITSNKSQDFVRVTFHPDFSRFGMPDGIDEDLEALLYRRVYDMAGTVTGIKVYLNDEHLKLDFKKYCAMYAKSIAKENGEDEGTEAAATVIMEDSKGHPRWEVAFAVSDGSFQQVSFVNSIATTSGGTHVNYIADKICDSLLKNLNKKKKGHALKSNHIRNHIFVFVNCLVTNPAFTSQTKEQLTTKASQFGSKCELSEKFLKAVGNTEAINNILHFAEQKADKLLAKSDGNKRSRISNAKLVDANLAGTKHGHECTLILTEGDSAKSLAVAGRAILDPDRIGVFPLRGKMLNVRDASIDQISKNAEIQNIKQFLGLKHKQTYTDTKGLRYGHLMIMADQDHDGSHIKGLLINFLQVQYPSLLLIPDFFQEFITPIVKIWQGPNPKKPLKIRSFFTQPQYEEWKAQHQGEVKRWQYKYYKGLGTSSNEDAQVYFTNLDDHMKGFDVMKPNEAQLFELAFSKKKADARKEWLGNFVPGTYLDHSTKSISYDNFVNRELILFSMADNMRSIPSMLDGFKPGQRKVVYACLKRNLIKDKKVIELAGYVSEQTAYHHGEMSLQQTIIGLAQNFVGSNNVNVLEPSGNFGSRLAGGSDAASARYIHTRLSPFARKVFSPLDEPNLEQWVEDGKKIEPKVYAPIIPMVLVNGADGIGTGWSTSIPNYNPEDIIKNIRRRMGRLDGPEEKPFEPMRPWFRGWKGVVGDSPDANRFVFNGLAEANDQTREVTIKELPIRMWTDDFKAKLEEVIKGEKTPSFIKDYKEFNDHNNVHFEIQMDEKHYGAAVREGLLEKFKLTKQIATSNLVAFDSRGMIRKYEKVEEILEEFYVFRLKMYKERKAHWLGVYHADYRKLKNQARFIKEIMDNDLVVSRKKKQIVVEELRDRKYEPFPKTNANKKTKADEDEAEGEGEDEGEAASDDDARDFDYLLSMPIWSFTQERLDRLKEQIAKKKGEHDELEALSEKDLWCRDLDEFEVEWNAQLALDAEIKTNIRRMGRRVSKKIGAGRGRKPKAADDDDFAPVKSKAAAKPKKEVVTKTKTIPQASSQRFAEKFAPAKKTTDGAADESDAFSDDDFAVLKNNPAKKAAEEQESEVEELSSVLPSRSKRAAAAKAKSWVIDDDESESEEDDDNMLGDVGALVKGIPGATGDSSGEKKSGRLSLFAMSRPESSHGNTAAPKSKTKSNKTFDFDSNDDTNYEMLARSSPHKTARNEVDSFLSDDDDVPAAKPASKLKSSTSSVEESKPNAPAPAVKKPRGRPAAAAKGKAKDDAPAPAPAPAKKKAAASSKPVELSPAAKLYAKKKGAEKAKPKKRSFDLDDDDDEEDDIAMADPDSPPPRAAARGRPGRAAAVKKKPVYVVDDDDDEDEDDDVQMDDDDAGANDDESDDFDMDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCN3</accession>
    <name>A0ABR1WCN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">feruloyl esterase</fullName>
            <ecNumber evidence="2">3.1.1.73</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_009010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.73" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668667.1">
        <property type="nucleotide sequence ID" value="XM_066813325.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046385"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043595">
        <property type="entry name" value="FaeB/C/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050:SF2">
        <property type="entry name" value="FERULOYL ESTERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045359612" description="feruloyl esterase" evidence="11">
        <location>
            <begin position="22"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="268"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8081192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="350" mass="36398" checksum="CC3ED8AEEA8FB070" modified="2025-10-08" version="1">MHISTALAVFLFSACTAAAAATCSPGSRPLPFPAGELSKDQFTAKGRRYRVHLPKSYDPTRRAPVILSYHGAHGTIEKQAALDGLTDPSRSNRDGDGYVVVYLQALVPAGASDPTKTEWQVAPAAAADKSHIDDLGFTADVLAALEASLCVDTRRLYATGKSQGGGFVGRVLACDSSSSSGLAHRFAAFAPVAGAYYILDTPRRAQCEPTDRVAIPCGGGGGGGAREEGTPATPILAFHGGADETIPYRGGVAPGDRQLPARHPALGAAKNTTIPGSRHGVRSAWGGSGGAGKDGEEEEEAARVVLVYAGDDIGHDWPSTAENADNKGGPRAAFNASDEMVDWFGKWRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDR6</accession>
    <name>A0ABR1WDR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668632.1">
        <property type="nucleotide sequence ID" value="XM_066813290.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046350"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="32836" checksum="3C2565DC3B3EB27B" modified="2025-10-08" version="1">MTATTPSVANGHEPHNVSAILNYWDDPGDGSSPTPIYIGKGRITNERPHLPHRFTVSDVAGREGDFTLDGQGFQYLRHPTQMKDDFVDERRIREEYYPECAALLKQATGAGRVHIFNHKVRRGPTQWHHLGLKNLANRGPVTKTHVDQSYDGAELRMRWELSPEEADDIVQKGKRYQIINVWRPIRTILKDPVAVADANTVPDEDLVSAIMVEDDYHGEQWVVRHNPAHKWYFKHGLTPDEVLLIKCFDSDRSVARRALHSAIEDPAYKDLESRQSIEVRCLVLYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDZ2</accession>
    <name>A0ABR1WDZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Regulator of phospholipase D SRF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668150.1">
        <property type="nucleotide sequence ID" value="XM_066812808.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045868"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037737">
        <property type="entry name" value="Srf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36819">
        <property type="entry name" value="REGULATOR OF PHOSPHOLIPASE D SRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36819:SF1">
        <property type="entry name" value="REGULATOR OF PHOSPHOLIPASE D SRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="34964" checksum="B6D0164676D99F79" modified="2025-10-08" version="1">MRHARTTPGVRVPSPIRPPPRRNTEGPTTGGPTRPGQVRRVSRDGYEQWVDPEDLRKFRRPVFMRKRADRPGRKWDHLRSSEPFIMGSGYRPPNVDPYEKWRDFIDSTRRYNGCADRPTHFITPDQLEAQYPGLNNPLVTKTPPPASQRRKTLAFRLKRMILLSPLLPPIVRLIALSMSLGSLGLATELLRKDELNPLRSQAVASIVIDSLAIPYILYMMYDEFTGLPLGLRSAVEKASLTLIDVLFIILKAVSTALALQTRGLHYNDISWNNYSSYLGLLVCAVVAWIFTFVIMLFRLVDRLKGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMW9</accession>
    <name>A0ABR1WMW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_006127</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="8">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669365.1">
        <property type="nucleotide sequence ID" value="XM_066810442.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043502"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF35">
        <property type="entry name" value="PEPTIDASE S53 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046816880" description="Peptidase S53 domain-containing protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="10">
        <location>
            <begin position="217"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="488"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="532"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="533"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="565"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="567"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8084856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="598" mass="64242" checksum="18B547F92DD0D743" modified="2025-10-08" version="1">MKLLPVMAPVASLTLLLPLAIAANADSTVVSLSKIPVGWEKVREAEPAHTIRLRIALEQPNLDAFEQILYDVSTPQHPLYGRHLSRDELAKMTKPREESTDAVLTWLQSSGIPASDVEDAGEWVNFRTTVGKAQSLLNTTFALYNHIGTDIKVLRTLQYSVPEDVKPHVTLIQPTTRFGQIRSQRSMVLTKERHEQLPVKAAEIPNLHLNAASCNITASPKCLRALYRIGNHTADPSVPSAIGIAGFLEEWAKFDALDQFLGQFAPYATTQNFSYVLANNGQDNQTDQTQDSVEANLDVQYVAALGYNTDIRFYSTGGRGLLVPDLDSPDPNHIQNEPYLDLVTYLLSLSDENLPKTITFSYGENEQTVPKEYAKSSGPGSDCQTNDGKNTTRFDPIFPAACPYVTSVGGTYGAGPEHAVAFSSGGFSDLWPMPAYQNASVTGYLQKLGSQWEGLYNQSGRGFPDVAAQAHNVPIVNQGNVEIVGGTSAAAPTFAAVVSLLNNARIKNGMAPMGFLNPWLYSVGLEGGAWTDITAGGSVGCTGTSISSGLPTAYVPGASWNATGGWDPVTGLGTPLFDTLLELAVPGYTLPPLGKGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNK5</accession>
    <name>A0ABR1WNK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Satratoxin biosynthesis SC1 cluster protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005893</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669131.1">
        <property type="nucleotide sequence ID" value="XM_066810208.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043268"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF57">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="73"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="339"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="432"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="460" mass="49441" checksum="D569AC5976BF5020" modified="2025-10-08" version="1">MSFKAGNAFLSPPILAWVMDLGLVARQGGGPTAPAAAAGVITTDLPPLSSRGIALIAVDSVMITLVITWTTMRVFAKRLKGLSPLMAEDILCYIALLCYSGSVTGHVICNHSLAAVVMGGVGHHQKELSPFHIARYAKLSFFAQIIYGPVIGCVKLSILFMLKRIFFTRGFRIATYLVMFVAFCWMLMPILVALLVCSPIEFNWNRRAPGGRCGNKQIAYALVGVVDLVSDLLILALPMRMVFKLQIKTAHKVALASIFGFSVITMVFTAIRLYYIYGMDFTDPTYSTIVPTTIGSVQMGIAIMVASSPLLRPIFDRTVASWFGLSVASGNWPSQKGSGYIADSSHRSHNNSHGNELLTFGRSSGLGASASKKHDSHHTPYHGGGSSHNRTAHHSDSEECLQPDGASSGLSDSGEGGWNYHGAARRTRVHVSGAERHSRGSQEQGITVTKSTAVVTGTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNQ0</accession>
    <name>A0ABR1WNQ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669651.1">
        <property type="nucleotide sequence ID" value="XM_066810728.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043788"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="68" mass="7654" checksum="5334A4F03F6AE6D9" modified="2025-10-08" version="1">MGVSGISVCFCVAYWIRSVQSRVDEVKQSLAGLVPERQKEIDVESAMVPSDWRGEEEEKLLPSGQRAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPA3</accession>
    <name>A0ABR1WPA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669868.1">
        <property type="nucleotide sequence ID" value="XM_066810945.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044005"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="346" mass="37893" checksum="4D2CF30906AF9124" modified="2025-10-08" version="1">MGDPNVLVTGSAGHLGCALMLSLPSLGYTPIGIDILASETTTHVGSIADRAFVASLFSRYPSIQHVLHVATLHKPHVESHSKSEFVDVNITGTLNLLEEAAAAAKNDNKAIESFVFTSTTSAFGRALSPRPGEPAAWITEDVVPILKNIYGVTKVAAEDMCRLVQAQTGLPVVVLRTSRFFPEADDDADRRALVGGGGDGDGDENLKVLELAYRRVDIADVVSACVCAMRKARELHWGKYVISAPPPFGKEPEILKRLDSNAEEVYVECVPGIKETFEKKGWRFLPRLDRVYDSSKAIQELGWQPQYTIHNAVNKIRTGEEWRSDLTFKVGKKGYHEVSTGVYTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPW2</accession>
    <name>A0ABR1WPW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670070.1">
        <property type="nucleotide sequence ID" value="XM_066811147.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044207"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="36031" checksum="1A164B516D381D9C" modified="2025-10-08" version="1">MHKPLERFHDFAAFLSGFTQREGLYRSRTWGYTIIRTVYGDGWDAKVQTALSAIRRTVQAMGEHDIARRNGEIDLFVELGGWPEDMAKMADRRIEDEFERRFVNEVFEDRDLFANATVDQVRAYFLRWAQERFDMFHPPATERSQRPANFRFRHLEPCSSRLFACILLDAETVEQLQGVPASPAELYPRLRDFWVKMVEAQPVPRQGPYYPDDGSMCDLYRVRLADLVDFWFDSSERNPEKSTEESDPQDKSIRYYNPHGWAPPEFKMKITHSTWPPTEAEVVPDPAPAFEHKGSKADTSQFWGSVMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ71</accession>
    <name>A0ABR1WQ71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669671.1">
        <property type="nucleotide sequence ID" value="XM_066810748.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043808"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="14"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="268" mass="31068" checksum="2518060EA2E747B0" modified="2025-10-08" version="1">MNNLSMMKKKMPAFRKFPNLPTDVRKRIWIFASIKPHTYVILWYPSEDSIARQYTLLWPGVLAGQSRRCEYGLLLANKESSEVVSQINKDTKPVSGLVHNLDLFINWDLDLLYVAAAPFDPTPAYSKNDSLRHIPSYAKYWTPLDAEPVGYNCRELRTLASNLPRDTHGFTNLRLLGPSLTSGIIPLLGTQFTEWSELNNYCRKVCEMIHHLRYKKNQAAWGTLNVCLAVDLDSNFNRGDFPDEYRRVGIRRSSREWYIAPERPMIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQP1</accession>
    <name>A0ABR1WQP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670365.1">
        <property type="nucleotide sequence ID" value="XM_066811442.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044502"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="697" mass="77322" checksum="F69A301E1C6CD053" modified="2025-10-08" version="1">MATKNNSATELRFAWRQRQQEIDEFVRYLPSTNVSAAFIAAQHASGKSTTLLAHISDVMQQDNAFANTTIFYLLPSEIEVKVLCNYVFSPESKPGTKAQTCFSRAIAPGKVFIADFDKGIAHFHEIYTRSKDGSSVLLVLDLEIAPTTAGEVLLGLASEWAACASKSADKGNGLVVLSSYTSPRALEALNRAVGRPPNLIQVPKVAVNMGMEVLEDDEVEHVKRLYSQQSGSRRLLIHHSPDWDHHLAVADKEKGRIRWIRSDYCPAVDQLISLRNIHVSVGTDFPCSFPVNGLTHVVSSCKVEVLVFRKDVAQPVTQVRDITELEYNRERSWAHKSSVPDDVMCYRPRAFLDAPMAPGIDVLGSAFLGNRYGTVLEYLAHWPGMAFSKMPTRAPHDFGMLRDICQKLELFGCIKSVAQNGRPVPGVYRLSDFGTRLLDLWHQPRHKALDFHVLHLLTTTYEGKESGWSRNLIRVAVRLAAIMSVGPRLSGKADSHAQQPLQQLQAEFAGVGMGQAHLCGLWASLGVFQKAKSEGSVNHLRIDVVRRGDVIFNVWYAYQVSNLVLKLEDGLGCHNGLSELWDTTLTAEEIEILEDALLSAWVDEVVVFNSQQSTWHEASTSRQVQLGSSEFLDSAALLQRDEFQHGLYAIYTKICGVGEDLIVKNATVIPQRVVKAAADRFGLPFSMAIASKYHASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRC9</accession>
    <name>A0ABR1WRC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxidase</fullName>
            <ecNumber evidence="8">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_006898</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670136.1">
        <property type="nucleotide sequence ID" value="XM_066811213.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044273"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00691">
        <property type="entry name" value="ascorbate_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF36">
        <property type="entry name" value="L-ASCORBATE PEROXIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 8" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="10">
        <location>
            <begin position="81"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="298"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8085627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="350" mass="38145" checksum="DA93419A9126406E" modified="2025-10-08" version="1">MPQNAPAPGAAPTAEQLEPVKAAVRALLHQPEYDDGSAGPVLVRLAWHSAGTYCKETNTGGSNGAGMRYEKEGGDPANAGLQHARAFLEPVKSQFPFISYADLWTLAATVAVAEMGGPAVPWQGGRTDYADDAKVPPRGRLPDGAQGADHLRFIFHRMGFSDQEIVALSGAHNLGRCHGDRSGFEGKWVNNPTRFSNQYFKLLLKFEGEWKKTTLKNGLQQFVYVDEDLAAGEEGEEKEEGLMMLPTDMSLISDSKFRAWVEKYAADQDLFFRDFAAVFAKLLELGIKRNSEGRVVNDENVEDGYRSAPKKSDAPGAPAKSQGPGQTGEEAAPLQKENEKYRRRAGGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWN1</accession>
    <name>A0ABR1WWN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670460.1">
        <property type="nucleotide sequence ID" value="XM_066806842.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039902"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="192" mass="21276" checksum="0E09801AB82AAF1A" modified="2025-10-08" version="1">MSALRFAAQLSGARYGHYHPYHAALRTLTDLVVAGELDRRTLLPTVFDWYYRFLGDYADPGHPLRSRAYQWHKVVRILELRSDPSWHNNNNRDTDKASSTHQISQNMNEIVRSMCRHSVICMPVPGESASQAAAAAAPTRQDNSSTAEDTVRPGSDRCGDYDDAICTSGGGCQDIWSHPQTASMTSCASSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXB5</accession>
    <name>A0ABR1WXB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7708 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002744</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670677.1">
        <property type="nucleotide sequence ID" value="XM_066807059.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040119"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619:SF3">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7708" evidence="2">
        <location>
            <begin position="58"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="224"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="507" mass="57988" checksum="381D072C38C5E370" modified="2025-10-08" version="1">MQHPLYNELGRGAGVLDSAAATYAETKGFKGALKKTKEFIESKAYTVQRVSSLVPEVDYAKPILGTLTFLLQAFQQTCKVREDVKGGIEKLKKNFGLVEDYIAMYSTNKKVAEAVTTIYITILKAIEEVIGYYTKHIFIKGLKAMWDGKNYEKSLLECLENISKDGNELIHEADTAHKQATNKVVEDLERGLDTMDIIDRRTVNIEFMVKSASKGIMVMVKDHLVAMEARYKRERARHEKEKARNEQDMQFLQRQIEQQNAENRELKQLFYRAITPELIPLATTTVVTQQDLLSFLDSTDVNTSDIEYIITQRELVIAGGQDRTEQIMKSPQLREWLVQAESKELLIHGNSEPEPISPISFFCALLMQNLRGVDQFKSLAFFCGSHPYDDFGGARLMIMSLLAQFLQQQHFDLVFVDHALAYRMDDGDIEAFCYAFGQLVRQVKSTDSVFCVIDGINFYEGLEEELLQDTAYVLRFLLDLTRERGLRLQDLGDQFLEHREHSTGYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXD4</accession>
    <name>A0ABR1WXD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002759</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670692.1">
        <property type="nucleotide sequence ID" value="XM_066807074.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040134"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052600">
        <property type="entry name" value="Nuc_rcpt_coact/corep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23295:SF6">
        <property type="entry name" value="NEOSIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23295">
        <property type="entry name" value="NUCLEAR RECEPTOR COACTIVATOR 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="386"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="759"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="770"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="879" mass="94784" checksum="8C9878989B6A69BD" modified="2025-10-08" version="1">MTEHHHQLEPEVVASADLEPCSPKPINLSSPAAVPALQDQVDTYYTMSQPPAADSLSHMQPYLAVSPIQLNGDEPHGAAAPMFGGEQEQNEQKDLQGGTADADGDDYAKAFDSPAAEPADDSQNDVPQGNTSTASAADVKGPSTTESSSDAISSKVASPTEQSTQPTDSSVQSTSNLPAADDQSRTDLPSQTDSKGLPAQTVNAASKSDLDTSGATQAGDPIDIQALVDNITARAAASDANQATSPPKPDDAQTAANSQHPQAQAPTQTSSLPPRPPVSQQPTSASLHAEEAKRFPHANAPTTFPVQPSTGMTYPYGTDASYPTPPTMNPTASPPMPMAQYSSAPGLPSNPHPSESQQQQQTYEIFLQEERKYVSEAKWDRFPEGSRLFIGNLSSERVSKREVFDIFSRYGRMAQISLKQAYGFVQYHDVAEGKAAMDNLQGAEVGGRKINLEPTRAQRKENNDGDRQRGNRGKGNNANERSRGDGRRRDDYRHRSPSPARASHSTQGSFGRDRNNWDSSSYGGRSRGRSRSPSSYNGGYRRRSPSPRYRGPPTTEADLDIPRRYAGDVPDVQLLLLQEVDRDFVTWVQRSFAERGLKVDVMFLNPRFPRDLVVQRQIVEGVHGVSELDFRAQSIAKIPLQVFDRSAGRHNARFDQYQDLDPAIAAELVARAKSLSQVPLPAAYGGGPYAPAAYAPGPAAHGYAAQQQSLGLASLDNATLQKVLAAMQSSPQSAVPGQPMMPNAGVDVNSILGALGGNSAAPPAMPHHVPQSQPPNSWAQASAPYGSMPPQHPSHAGDNAQHVQNIMAQLSRYRQCELFTSGPSAGEVSILFAAGPSSRAVHLGPFCRRGIYPIRCWPFQQSFENLVLFSFNDWRERER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXH2</accession>
    <name>A0ABR1WXH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670758.1">
        <property type="nucleotide sequence ID" value="XM_066807140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040200"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002745">
        <property type="entry name" value="Ptrans_KptA/Tpt1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01885">
        <property type="entry name" value="PTS_2-RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="304" mass="33092" checksum="20C79F867D33F290" modified="2025-10-08" version="1">MAAAVLIPLSTINQNGGILPASALTQHVPRHGRSRGMSMKGKSAKGRSYSIVEDSDVTVAKAISFLLKRAIKADETEAESADEDNDYLIADAEGWVSVADLLQHPNMTELRVDLEGVQQAAASIRARFTLRQKPDTDVKRADSYQVRQNGKRTSLQAPDSDNLPEYAVYETTYQAYPLILAFGSIKRADGATHSPFSAVNTSDAEVSIWVHLRTAMEQAPEITWQFTSTGGLVTSEEPLEKAVGRRQDVGLLLEDGEVRKEVPGYLRGKGGKGKAKKGKGMLRQEGQEGRVASESSDSNNEEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXU6</accession>
    <name>A0ABR1WXU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670843.1">
        <property type="nucleotide sequence ID" value="XM_066807225.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040285"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="134" mass="15467" checksum="8765ACEFB5EF9130" modified="2025-10-08" version="1">MATRSKRQDWKDLRSPEDLKMYVGVHDYIAQLIRHGLVKEARYPNAASRRASEEKQAQYDPVRNTAFAAVASNYRRHARKQLEDLGCDLDQLESPLHLTQAHPLRQMTTRLLLVYFLMLLSSILLHALNVKGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXV0</accession>
    <name>A0ABR1WXV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670876.1">
        <property type="nucleotide sequence ID" value="XM_066807258.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040318"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053225">
        <property type="entry name" value="Acyl-CoA_N-acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013653">
        <property type="entry name" value="GCN5-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958:SF6">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08445">
        <property type="entry name" value="FR47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GCN5-related N-acetyltransferase Rv2170-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="84" mass="8923" checksum="A00850BF962D4DA9" modified="2025-10-08" version="1" fragment="single">MLEDGTPISWCFLGPDASLSSLHCEEPYRGRGYAKAVATKLIKDHLKDYGGDDSTLCCAEVASNNPSSQGVCKSLDGKIGWAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY34</accession>
    <name>A0ABR1WY34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003034</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670967.1">
        <property type="nucleotide sequence ID" value="XM_066807349.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040409"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052743">
        <property type="entry name" value="Glutaminase_GtaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032514">
        <property type="entry name" value="GtaA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033433">
        <property type="entry name" value="GtaA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987:SF1">
        <property type="entry name" value="GLUTAMINASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987">
        <property type="entry name" value="GLUTAMINASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17168">
        <property type="entry name" value="DUF5127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16335">
        <property type="entry name" value="GtaA_6_Hairpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046066431" evidence="1">
        <location>
            <begin position="21"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A N-terminal" evidence="3">
        <location>
            <begin position="106"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A central" evidence="2">
        <location>
            <begin position="344"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="693" mass="75124" checksum="804928C219886FAD" modified="2025-10-08" version="1">MRLSIAAVAQVALTGGLVHAASTFSPARPPAIPLAVRSPYINTWLPVGKDGGNGGYLAGEWPQFWSQHTNGWVGMIRVDGTAYTWMGAAANGPAAVDQTEFSYTSTRSTFIMDVGGKVGMNITFMSPVTPNDLKRQSLTFSYLDVAVHSLDGSTHDVEIYTDISGEWASGDDSAVLEWDYNTASGVAYHTITRQQQNEMAEDREQAAWGTWYWSTADGDGLTYQSGPDVDVRASFAKNGVLANSKDTNFRAVSNQWPVFGFTKGLGAVGSESVSTLFSIGLTQDNAISFLGEGDGLTKVPSLWKSYFSSSLDAMTFFYNDYSTVSGLSTDLDNRVASDSLAAAGQDYLTITSLSVRQTFGALQFCGTDSAPLVFLKEISSNSDIQTVDVIFPSMPLILYTNPKLLAYMMNPLFINQENGHYPNTNAIHDLGTFPNAKGYPAGNDELMPLEECGNMIIMALAYAQRTSDTNYLNTHYKLLKQWAGYLVDDSLVPANQISTDDFAGSLANQTNLAIKGIIGLRAMSEIAKMTGNSDDEKSFGDTATSYLSQWQNLAINQAANPPHTTLSYGDGDSHGLLYNLYANSLLGFGTSFVPQSVYDMQSAFYPTVALEYGVPLDTRHTWVKSDWMLFAAAIASSDTRDMFIKKLANWISATPTNRPMSDLFDGNTGDFPGITFNARPVVGGHFALLALPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY79</accession>
    <name>A0ABR1WY79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA mismatch repair protein S5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671017.1">
        <property type="nucleotide sequence ID" value="XM_066807399.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040459"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF41">
        <property type="entry name" value="MISMATCH REPAIR PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="346"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="516"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="560"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="560"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="610"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="643"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="868" mass="94000" checksum="1A7EBC3A34C78F85" modified="2025-10-08" version="1">MPIAALPESVAKRLAGHINIASPVILVKELLDNAIDAQATSVEVIISSNTVDKIEVRDNGVGIYPDDYDSLGRRGHTSKLKSFEELNLRAATSMGFRGEALASVNSVAKVCIITKTSSDPVAASIQLHPKTGGVLTHNPASAPVGTTVIVTGLYNDTPVRERVTVQEAPKSLDGIKELLRSYAIARPLLRLQFKVLKAPRLGWSYAPKSTAGLQEAVLQIHGAAALSQCVEKRFNYDTSASHNDLSQLSFGFEVVAVKHGALTHLLPKGRYFSVDRRPLTATRVGSYDANIEPSKNEVLFSDEAALIQQFEKFCAEIYGQLAAKPPQMAPIDDVPEAAPSAALDGVGRLDSTTQDCQTANNQPSPDARARGRDDQFHATDSTCWGKEHGSEPVRKGNRPSTPAPPGFIAASTLRRGDQQQALSDRPSAPDIEPPVSDRGWAGDMSSDLSECVDRLEKRRIQPRHPLPTNKLRLSGGKVHNDESVIVPVRPPDPWSIARANTSAPRNDLFGYGEVDKVAGSRPTPEPDILHHYGAAPRDLDIPSNYRFAGADRDEISSPTVSFRQPYASPQSSPLVSNHQRTSNSQAQNAISRRRAQPPWTPPSSIRRDQQGWSSSYHSGYQNGPRKASSLSNVSHEQTKLDQFISNHCSTSDSGAHGSSNDPFASSKGANTLSQNGTTGGNRMLNAGVARVTGVPRGSQNLVRRHGDSEPRIASFPQISQNQQTAEDHEPIKTSIPPGDPRAYLLRRQKSAAAEANSKAPRRGLKRAKSCLMPLENIPDDEVTYNLLFQMPLEIQLLHNSTALAACFDGYIDDDDVGSALDMGATEGRRIEERLDHLLSDWNKQVTGETTCIESQLTAVLKGKGIEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYL3</accession>
    <name>A0ABR1WYL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LIM domain-containing protein C4F6.12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671113.1">
        <property type="nucleotide sequence ID" value="XM_066807495.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040555"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF8">
        <property type="entry name" value="PAXILLIN, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="5">
        <location>
            <begin position="673"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="5">
        <location>
            <begin position="827"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="158"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="206"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="271"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="385"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="420"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="496"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="552"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="633"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="886" mass="95756" checksum="3F2C161766F3EDF8" modified="2025-10-08" version="1">MLLRGKSKEGSGKASPPNPSPAYMDSKQFAAYLASLRENRVNRPGTTSPQSTAPAISSRRESDRFSAGRPTSTVYSEASATTIPQAASSIAAKDRSTRPSIAPSVSSRYSTAIGGRDYYPEKPSAATPLKPNEVVPSATYIERGSRWMEKEEAFSLRAAMEDMDLQQRGRSGSPQQSEQGSGNSSPVDEAEARLYNAALDEAAELVWQHQHGVKPPEPGTPYHYKPHMRKDSYAHARTASIGRYGSDIRPSGLARDGSRSGSGSGSGSGSSSGSDGRSSLESSRPSMEGRRRTSDESTKQKSYGNMGSGKRTPSGGRRRSSMKRNITGEIEKPFSGDQIWEEPEGDSTRGNTPKAAPPSTQQPDRASRDTLPLRLALRNPLNKVHTGSGSTSPDSDARNSSPVNASPTKSLQKVEIYRNPPTQTRNPNYTVNTQKPAGPRESDKIPKKNGVEIRSDDIRQATSFKLGDRSAKLPTPSAVSDRPGRPIVSFDSNWKAPEEAAADHKPERKEPRRFTVGSLPEPGQGESQKDYQPEPQKSQQKASPLPPVPSHSFTPPAVSASTPSSTSRPSTSSYPSVPSISIGGPESRASPPVNMPIIVTPDDSPTLPTINVSTEDDRTPNVPIIVTPDDNKPSAGSSSRPSARPLPTPSKVRNAGRSHWSPAPGSVSNRATAVCHECRFPIEGRFVALHGGRERFHPQCFSCYACGTGLEALEISPEPDEFRDARLDRIARRAAGEVLPEEPGQTMAEDGDHRLRFYCHLDWHELFAPRCKHCKTPILGEHIVALGAHWHYGHFFCAECGDPFEHGMTHIERTATPGASTARPSAPSCKRCKVAVIGQYVQALGGEWHDECFRCGTCGGGFADGQIFPAGDRILCKTCRMRELKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ39</accession>
    <name>A0ABR1WZ39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hypervirulence associated protein TUDOR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671299.1">
        <property type="nucleotide sequence ID" value="XM_066807681.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040741"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021331">
        <property type="entry name" value="Hva1_TUDOR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11160">
        <property type="entry name" value="Hva1_TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hypervirulence associated protein TUDOR" evidence="1">
        <location>
            <begin position="7"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="75" mass="8185" checksum="3A74462C6059F112" modified="2025-10-08" version="1">MTQYRRGQTVRYKPVGGADSNTLESTGKILSVLTEPGQQAGLNVDASKENPRYEIENANTGKPMAIYEDNILGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZL6</accession>
    <name>A0ABR1WZL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671505.1">
        <property type="nucleotide sequence ID" value="XM_066807887.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040947"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07735">
        <property type="entry name" value="class_II_PDE_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000396">
        <property type="entry name" value="Pdiesterase2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28283">
        <property type="entry name" value="3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28283:SF1">
        <property type="entry name" value="3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02112">
        <property type="entry name" value="PDEase_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00388">
        <property type="entry name" value="PDIESTERASE2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="511" mass="54863" checksum="405BDA2D57E4FF0B" modified="2025-10-08" version="1">MDEEEKGSALQVVILGSGGGPQENNVTAMLVRSTHAGWARGSVVALDAGVHLSAITRILEDTQPEGLGTRIELPHILQSGPFAGLELKSKSPSANASLIARQLIDTYLITHPHLDHICGFVINTAGLPGSRPKRVAGLPSTISALKTHIFNNVIWPNLSDENNGAGLITYMRLVEGGSPALGEGEGKGYLEISDGLAVKVFGVSHGHCIERHSHRGSASSSRLGSTDVSMMSPRGVPGSGAASGPSALFRSTSMTRMSGSQEREHMCVYDSSAYFIRDEHTGRQVLIFGDVEPDSISLSPRNSMIWQEAAPKIVSGQLAAIFIECSYDDSQTNDRLFGHLCPRFIIEELRALVSEVEHARQVSSRLESNKKRKRDLEEALGRSPKVVARSTGDDQPVSPKSTRPSPNGISIGPGHGSISDEHPPVDSPHIATPTAELTLKDLDPTMKAVLPPLPTVHPLKGLKIVIIHVKDNFSDGESTGEIILSELLEYEQEVQLGCEFVVSKPGQSFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZM5</accession>
    <name>A0ABR1WZM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Ebp domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_003586</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671519.1">
        <property type="nucleotide sequence ID" value="XM_066807901.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040961"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007905">
        <property type="entry name" value="EBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033118">
        <property type="entry name" value="EXPERA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207:SF0">
        <property type="entry name" value="3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207">
        <property type="entry name" value="STEROL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05241">
        <property type="entry name" value="EBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51751">
        <property type="entry name" value="EXPERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="7" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="10" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="EXPERA" evidence="16">
        <location>
            <begin position="70"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="291"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="335"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8088625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="383" mass="43043" checksum="B9F22CA96C33B09B" modified="2025-10-08" version="1">MSMVLFDWVWGGHHDRTLASGTMTGTMRGAPAPPPIPLHPYYPLGVTIPSYQANSASVPVLLVSLAGMLASVLVLASTVALRGSLHCFFEGYFVFNHDTVASSQNLFAQLWKEYALSDSRYLTSDPFMLSVESITVFLWGPLSFACAASIVLDSYLRHPLQIVMCIAHLYGVALYYSTSLVETHFTHLAHSRPEFLYFWVYYVGFNLPWAVVPAALLFDSVKTLRSELRILDSVRTGLAGFQAHSPLNSAKVPEESKEIKEIQKIQEIKETQETPEIKGIQEIMEALEAEETKEIEETKETDETDDINEATKIDDTHDTDENNDKNDINENNDTDETKDTKDTKDTKDTEESKGTEDAELSKKLEGLKEPEDTEEFEEVKREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0J9</accession>
    <name>A0ABR1X0J9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SET domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671834.1">
        <property type="nucleotide sequence ID" value="XM_066808216.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041276"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045833244" evidence="1">
        <location>
            <begin position="20"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="120"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="47506" checksum="A2AFF5D9B328BBAA" modified="2025-10-08" version="1">MKSSQFLLLPACLLPCAQARRSPDGPYYNGDTCPWGPFHLPLSMSCLVSDPQNPAALQSRLDSDQIAPPENGWVGPHFCLGRFCVWSNDGYGDGGASVVTTLSNRHRVAQMSDRSPGGVHDISHFRAVVVPGKGIGLVANRLIRRGEKIMAARPAVVAHEDLVDELELASQNALLDQAARVLPGERRKRFLAQAGELGGHRIADIMFTNSFQVSLGLQGGHTLAIFPKCHVSTMIVGPGQLKPPPRDNNTRVQLTWEQSLAYYIDQNLTHHTHAVRDIQPGEELTISYLDSFRARSVRQARARASWGFSCGCSQCSLLEAEAEASDARLFSIYQVETQLTDLKNANVSTSTIDRLVALYKEERLYHKIADAYTLAALNYNTFGVEATAKEYAKLSLEQGLLEHGNDSADMEAMRIVAVDPKSHWSWNTRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X186</accession>
    <name>A0ABR1X186_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcriptional activator HAP2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004118</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NFYA/HAP2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672051.1">
        <property type="nucleotide sequence ID" value="XM_066808433.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041493"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12632">
        <property type="entry name" value="TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02045">
        <property type="entry name" value="CBFB_NFYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00616">
        <property type="entry name" value="CCAATSUBUNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00521">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="105"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="239"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="240"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="299" mass="32310" checksum="F7E0FD49968572CC" modified="2025-10-08" version="1">MEYAQYQQPQSAHSQGHIQPGYTNTTGGNTITSPTSHTIPHHGVQSSPILPNQHQPATSGQNHNMYQTQYSVPQQNMHYGVPGIQAAAMAATAAAAGGTGYSNYMPSDPSLPQTSPRMGSGVGGKKDGVGPRSPQQMSQMPSGRRLSQVTSPAPMPPAQAMPPPQSPEMTAGAEESPLYVNAKQFHRILKRRVARQRLEEALRLTSKGRKPYLHESRHNHAMRRPRGPGGRFLTAEEVAEIEKGKGDGKTDEQAVADVLAKAGTKRKSEASLGQPHKKAKLETESPEEEEEEEDAEDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1G4</accession>
    <name>A0ABR1X1G4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome b-c1 complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Complex III subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_004180</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UQCRQ/QCR8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672113.1">
        <property type="nucleotide sequence ID" value="XM_066808495.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041555"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.210">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004205">
        <property type="entry name" value="Cyt_bc1_su8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036642">
        <property type="entry name" value="Cyt_bc1_su8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12119:SF2">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12119">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02939">
        <property type="entry name" value="UcrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81508">
        <property type="entry name" value="Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8089219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="101" mass="10939" checksum="652D73A8C19CF574" modified="2025-10-08" version="1">MRPTQMLQAGGGDAPLGKYGKYLGGWGNFDAIVPGQTTELHECLDTELLTVWHPTGGSKQRGIITYGLSANRQNPLAGAAHAAIFNSWRRFRGQVLYVAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1W9</accession>
    <name>A0ABR1X1W9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transporter particle component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672280.1">
        <property type="nucleotide sequence ID" value="XM_066808662.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041722"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14944">
        <property type="entry name" value="TRAPPC6A_Trs33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037992">
        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="243" mass="26326" checksum="1367249A9C32E9D4" modified="2025-10-08" version="1">MSNFDQPLPPFNASDPTASFLSSSCLDFLLIEIVPMAYRVANEVDAASSESIPHSEKSAAETAATAAAGTTTTTTGAAGGGGAATDGHRTSGRLDEEEERDAVFYRLETLGYRVGLGLVERFSRDRPRFNDTLDVIKFLCKDLWTLVFKKQIDNLKTNHRGVYVLTDNAFRPLARMSTETGGQAVLRAQPVGLSSPPQGRPYFLSTDTNPDVLPKSVPLVSMWYSTGCSGCFRNQCDGASRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2U9</accession>
    <name>A0ABR1X2U9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004620</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672553.1">
        <property type="nucleotide sequence ID" value="XM_066808935.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041995"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16180">
        <property type="entry name" value="EFh_PEF_Group_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051426">
        <property type="entry name" value="Peflin/Sorcin_CaBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212:SF3">
        <property type="entry name" value="GH27120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212">
        <property type="entry name" value="PEFLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="185"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="251"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="287" mass="32335" checksum="8474507A04CEE4AC" modified="2025-10-08" version="1">MAYNRPYNPDELPRFAEPDDGNAPRPAQQYSSSSASKYNSKPPPPLPQQHAAPSPYHRNSDGRDRLNPSSHGQSNYGRHSPVSSVMSPPPMASGPRPTTHNRPPASSRPPPSPAPPEGADPTLLPLFRAVDKDGTGQLSERELSAALVNGDWTAFDLHTVRMMIRMFDSDRSGTIGFDEFCGLWSFLASWRTLFDRFDADRSGNISLDEFSNALVAFRYRLSPRFVELLFSTYDKRNEGVMSFDLFVQACISLKRMTDVFKKYDEDRDGYITLSFEDFLIEILKQMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X326</accession>
    <name>A0ABR1X326_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672628.1">
        <property type="nucleotide sequence ID" value="XM_066809010.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042070"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="216" mass="24853" checksum="F9C769E42ABA3FCE" modified="2025-10-08" version="1">MPEHPFSPEDFPIDEDHEFKPTNFYFLKGCVHFKNTAQILDMTNKVKKSRWRDFSQSFLRDVDNAAKKADEDQEKPKYEIKSCGEMMRTIKTMVDGQKGEKICELSMTFVSFDSSMVRFPDKEHSRHPLEICPVEAGSENKHECFVRHSIPYFWDMSSQFGTLYKCLNQKRVKIASICAFGFGKDAVLAIEGDQLDDVCALSTCIILLNGRDAMDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X397</accession>
    <name>A0ABR1X397_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NPP1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004856</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Necrosis inducing protein (NPP1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672789.1">
        <property type="nucleotide sequence ID" value="XM_066809171.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042231"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045319045" description="NPP1-domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="26088" checksum="154AEE9E924B43E9" modified="2025-10-08" version="1">MGLYMLFKAALGLAILARQALAHPVQQRDPIGNADIVGLPESVPSGTAGELYLKCKPYLLRDSGCVPYPAVDARGNTNEGLEPKGSRSADCLASTGQIYSRAATVNGSHAIMYAWYWPKDVPSEWESRLGIGHRHDWESIVVWLASASLDAAVLGVAASGHGKYTTTKTPHFKGSGVLIKYFSIIGLLDHSLGFTASVGQQQPLIAWESLTSVAQNALSTTDFGDATVPFIDSEFQKHLDSAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8F3</accession>
    <name>A0ABR1X8F3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673625.1">
        <property type="nucleotide sequence ID" value="XM_066806329.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039389"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01277">
        <property type="entry name" value="HINT_subgroup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039384">
        <property type="entry name" value="HINT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648:SF1">
        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="HIT FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="11"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="99"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="139" mass="15505" checksum="8DF2C87B6F54B8F4" modified="2025-10-08" version="1">MAAIHSDSNCIFCKIIKGDIPSFKLFDSDKTYAFLDIGPLSKGHCLVIPKYHGKTLQDIPDEHLGEILVVVKKLATATGSTNYNVLQNNGRIAHQVVDHVHFHMIPKPNEEEGLGVGWPTKSADMEELKKYCEEVKSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9Y5</accession>
    <name>A0ABR1X9Y5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674246.1">
        <property type="nucleotide sequence ID" value="XM_066804473.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037533"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="548"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="745" mass="82317" checksum="C9AD41C65753B65B" modified="2025-10-08" version="1">MDTDGQVYLGVWTNWSRGSAIMGATLTTTQSTGNILIAFTATFIPFVASRLWKMFCFAVHTCSSKRGSQGTIYHQRQVVLRNSSSADSGAFSLLALLWTWRRLPAKSLSRLLPLLIFAILFIVGFTVAGGYSSQITSTMGDEVLLKGDNCGMLTLATSEDDYDRASACYANQAANVFDCNRFIVGSLPTETADGNAACPFASDVCRDNATNLRLDSGYIDSNDHMGLNAPQDQRIFFRMVLSCAPLSTRGYKTSHIQGNRTFVRYNYGNLIGANYNLFDYTYAVPDRETQYKQADATNNGLNFRVSPEVSRSFNNSWFPLDSTFVPNRTIETTDGDTLLVFLSGNGVKFLQESDDAWYRATNPYGSVNASYGGGSGQVFTPTEEASPLGCVQQWQWCKSGSGNARECGPLAGWMDAMAGAVHLVNSSSNALDASLRGNKSGSKIGWISGISWMSKSSIYDLLLTFGAKALESQSLLSAGVQLGVSKNQWQLDVANWWNITLAIQQAAFVSTAMGYPEVDTSLKSMIYSPKNDEERHLCQNQKIRHKGYASFSLFGLLFTYIFGALVIVMSFALDPIMRCLHTRRKYRQYQYLEWRTNGALQLHRLAQDELRYGKWSGCTEIVPITHPEDRLADLDISDLEYPRLNGGVVGEDTKPEADSHTEIAGSDQVSVETSEDTMLNTDAQNASSESLRTSEAEPTFPSLAEESRRPEAQRVSMLSEEEIDGVHAIIYEADAENTQETNRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9Z6</accession>
    <name>A0ABR1X9Z6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674238.1">
        <property type="nucleotide sequence ID" value="XM_066804465.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037525"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053238">
        <property type="entry name" value="RING-H2_zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14155:SF627">
        <property type="entry name" value="OS06G0192800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14155">
        <property type="entry name" value="RING FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="150"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="207" mass="22254" checksum="38A3D5004C98DE71" modified="2025-10-08" version="1">MAGPAPNSTFSDPGHGPTTTVNTGSIAAGVSIALALALAVIILIARNSGAFGPLGALSETTSTSSPKHAHGLDSTLVNSFPVIQYKQPKTGYDEAARKPRGLSIDEEAGQSRSKQQGRNQGGILDRLRIPMRNTILGRPHTRRGGQGTSCTICTDDFTEGVDVRKLPCGHLFHPPCIDQWLAEFGVTCPVWQVNLFPSWPWRCRLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA67</accession>
    <name>A0ABR1XA67_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674314.1">
        <property type="nucleotide sequence ID" value="XM_066804541.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037601"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="184" mass="19897" checksum="02805273C59387A7" modified="2025-10-08" version="1">MSRFNNLNIQVGNSSGQPASGARPTARPPPQHDHSCLEPGEKGDEETVVACIRLGFYLPCAIASLPSFDCGGRAQLAHTESIRAPLPNRLPARREADDLAVRGLVPCVKATLRHVVREALETRGFVLDGDDDKQRDTGRWEEAEDEFEAAVGALDEEIVLHALGGAIAQIREACEDYEKEKGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAY1</accession>
    <name>A0ABR1XAY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000545</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674633.1">
        <property type="nucleotide sequence ID" value="XM_066804860.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037920"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045398258" description="Tyrosinase copper-binding domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="408"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="421"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="542" mass="59640" checksum="BFDE592A5B2CBD8D" modified="2025-10-08" version="1">MKSLGNSVLLTASLLLCQAIAVPLSTQEISQADIDSGKALTDYSKTAFDNAMARLDKSDTGCTKDNVKIRKEWSSFDDFAVLHVAFTPYVHNSATFLTFHRYFLKTYEQRLEDQCGYTGTIPYWEWGLDCDDIDKSPLWDGSETSLGSNGEFIANKPNPMSMFGAKAGTGGGCVKKGPFANYTVNLGPVSAAKPLGYNPRCIKRDLNSDICAKWASLGNTTLTIRDGSDVEIFQALLQGDFRYKQASRLGMAVHGGGHFTIGGDPGGDFYFSPLEPGGIAGTGTMMNMPASRNVTLDDTLDFSPMNPKREIRELIDTISGPFCYVYEYPWHDVSPQHQEAVQSFFAKHYPDAIDPVQDLSSADYQDQLIGDMFHDWNTKDKPQVPKISQPQIQMQFFSNVHCVTNSNPFNNGSTSDVDAASQDPSNDSNSESDINDAGLLMATFPWAAGPEAATEPAQTEASHEKPVDAGPWKDQTEFAKHYAEQNTQILIFLARKYLYNANRIEPWSPKHDGEPSVSIADIKKTPSAPGYLMEAMLKAMYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB01</accession>
    <name>A0ABR1XB01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="9">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_000521</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674609.1">
        <property type="nucleotide sequence ID" value="XM_066804836.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037896"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 17" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="13">
        <location>
            <begin position="43"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="12">
        <location>
            <begin position="194"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="14">
        <location>
            <begin position="457"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="559"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="641"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="10">
        <location>
            <begin position="688"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="11">
        <location>
            <begin position="1059"/>
            <end position="1144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8093836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1153" mass="129779" checksum="774693744CA024CF" modified="2025-10-08" version="1">MPHIDDGFEALLEPFYNGKKLTDPISTVDDKMQLLPAFLKVKGLVKQHIDSYNFFVDHEIKEILKANRTVRSDANSSFFIEFLDIRVTKPDRPGFNEGPQPRNEISPMECRLRDMTYSAKVLVDVAFFREKKRVIQRNLELCRIPVMLRSNKCYLYGANNAEMERLNECPLDPGGYFIVGGTEKVILVQEQLSKNRVIVEADEKNNIIQASVTSSTHERKSKTYVILRKDRLVLNHNVLVEPVPIIIILKALGGLSDFEIMQLVAGSDGRFQDDFVVNFEEASKVGVFTQQQALDYIGARTKMGGRGKPGAGAPQARRSHVEEGLDALANIIIAHIPVEGLDFYPKAVYVALMTRRVLMAYYNPKLVDDRDFVGNKRLELAGQMLSLLFEDLFKKYLTDLKFAADNVLKKNNRASYDPLGPIIANGRHISEGMNRAIQTGNWSVKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKTRKVSGPRALQPSQWGMLCTSDTPEGEACGLVKNLALMTHITTNIEEEPVKRWVFTLDASIEPLRCFSGAEMHAPGAYVIYINGTPFAMTRFPKQFANKFRTMRRRGWVSPFVGINVNNNLAAVHIATDEGRICRPYIIVKNGKAKIQASHLRLLQAGKVTFDDFLTKGIVEYLDVNEENDALVALYEKDITKAHTHVEIEPFTILGAVAGLIPFPHHNQSPRNTYQCAMGKQAIGAIAYNQFNRIDTLLYTLVYPQRPMVISKTIELIHYDKLPAGHNATVVVMSFSGYDIEDALVLNKASCDRGFGRCQVFRKYSTELQKYNNGSRERIGDRDPSQAAGKHIALSKDGVADVGWRVEAGNVMLKKETPVETNPGVGMERRSDEYKESPVSYKLHDPAYIDKVMVTQTDKDTHLIKIQTRQTRRPELGDKFSSRHGQKGVVGIIVDQEDMPFSDKGLVPDIIMNPHGFPSRMTVGKLLECLTGKASIVRGRKDFGYGDAFRSHPLEEMSRNLVEAGFSWEGKDYFTSGITGEPLQAYIFNGPIYYQRLKHMVQDKMHSRSRGPRAILTRQPTEGRSRDGGLRLGEMERDCLIAYGASQLLLERLMISSDGTDVDICQKCGLFGYRGYCSTCRTSREVAKMTMPYAAKLLIQELISMNVGVRLQLEDEFPHPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBB2</accession>
    <name>A0ABR1XBB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000615</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674703.1">
        <property type="nucleotide sequence ID" value="XM_066804930.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037990"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8093930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="58965" checksum="7C86AD88B2DE7C76" modified="2025-10-08" version="1">MAEILAVDQFAALLAAISLLLSIFCIQILWKPKPSLSKDVPILNAKNGEIFPYLRAAWRNTLDLKSALSLHRSQHNGQTVRVPIVGPGKLVLLPTREAKWLIDQPENVLSMHQQTDLHFQTAHKTVYPLRNQAHVHLVMTKLTRQVGNLVPVLMDEIEIAMPQAWDGTASDENVWQEVDVFDTLRVAIGQVTNRVFLGTPLCRNRELLDAGVAYAQAIPVAAQLISLFPASLRWLMAPLITMPNRAYEKTWFKLTLPEVEERLRGYPNGGLGKADFLQWSLQQAKESGDDYMWDSKTLAARLLLVNAAAVHTSSFAITHVLLDLVGSGTKRGSEYVAELREEIQQVMAAHGVWSKRALDDMHKLDSTFRESQRLNTVLTVGPLRIVNAREGVTTPSGVHIPKGYQVGIPAYQMHMDPSIWGEDVEEFRSFRFLTNTKLQETDEFEPAKARQPWVTTSQDYLSFGGGRNSCPGRFFAAAELKLLLAHILLNYDFDFQEGRPPNQWFGTNHLPPKKATIRVKKRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBD3</accession>
    <name>A0ABR1XBD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674799.1">
        <property type="nucleotide sequence ID" value="XM_066805026.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038086"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="entry name" value="Haem-degrading domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010371">
        <property type="entry name" value="YBR137W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255:SF1">
        <property type="entry name" value="UPF0303 PROTEIN YBR137W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="HbpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="GlcG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="199" mass="21664" checksum="CFBDB960802B3DAB" modified="2025-10-08" version="1">MSSEKVLSRANKEPGAGLKPSWTPRRQPARRPLLPIPQRTYAEEVKAQCDTFVLDSFTADDAWELGHLLYARLLPLVAAKGRPTLISIASATGHVLFQAAVGAGTQLDNTVWIQRKRATVLRFGCSTWLMHCKFGGDEEAFRAKYTLSPDLAAGYAIHGGGVPIRVRGVEGVVAVVVISGLKQHEDHGVIVDVLNANWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC01</accession>
    <name>A0ABR1XC01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter maltose permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000832</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674920.1">
        <property type="nucleotide sequence ID" value="XM_066805147.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038207"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF83">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="525"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="97"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8094147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="580" mass="63008" checksum="B61BC2E49132F142" modified="2025-10-08" version="1">MEAGADDDQHVSVVACRRQFTTSAAGEEGDQDSTTNLITSAAATAPVAMNTVDTADDPKRGGATTSADHVVLTEAIQHEHSLAFWQAVKLYPAAVGWSMFVSIGVIMLAFDPQLLGNLYATPQFAADFGYEYEGNPKQMQLEVLNGNPKGAPWQTGLSMGNPIGQVIGALISAYPMDLFGRKRTFGVCVVLTGGLVFIQFFARSLPVLLAGELLGGLVLGCYVVIAPAYASEVCPLALRGVLTSYTNLCFVMGQLLANGVTAGTSQLTDHWAYSIPFALQWFWVAIIIPGMFFIPESPWWLVRRGRFAEAEHALRRLSSKQVDVAATLAVITETDRLEQEIEAGSTYWDCFKSVNIRRTEISVGVYSIQVLSGIYLINYGTYFFKLAGLPTDKAFDMGIGFLAVGFVATIISWYLLTIFGRRPIYLHGLSALVVLQLLIGILDCIPGRPAGVAWAESSLMLIWNFAYDLSVGPVCFTILGECSATRVRSKTIAVATAAQALVGIAMTVAIPYMINPDEANMQGKLGFFFGGLAALCYVWAFFRVPETAGRTYEELDILFAQKVPARKFKTHRVDITDPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCP7</accession>
    <name>A0ABR1XCP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675249.1">
        <property type="nucleotide sequence ID" value="XM_066805476.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038536"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345:SF1">
        <property type="entry name" value="VTC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="369" mass="41908" checksum="1415274B6FE89B45" modified="2025-10-08" version="1">MSDEKKGFWAGLRRSMTAEAGERGGSSAAQTGVQRPRHAQRSSPAPPCEPTGLKGKGREDVNGHSYESSPLSEWPPPGVSSQEELTLGHAMELISRGVPAHKGHKRPIPHRPEQYYALYATTAGNKGDETDAANAHDSMTQLMTVRIQGSSAPAYPWDTLEQPSQAFGIGSRPGTITLNQWAFLSSNIPPMMELRDPGINPREVTLVEIFERLKELEVGLEDDNDQLMYRNLYKRFLKDPDKAVSPHRSMDRQITDLIMVLSRPDWLDFTLPKNQVVTKFIYDTSPENHPRYLKFFHQLLLSLELDLRINSGMHNDWAKSKLMEQIPPKIQWNLALSRRWKDNVRIEQYGKTADEVRLRFKLRKRQGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCV5</accession>
    <name>A0ABR1XCV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_001139</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675227.1">
        <property type="nucleotide sequence ID" value="XM_066805454.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038514"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF74">
        <property type="entry name" value="HISTIDINE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="1034"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="1154"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="1219"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="118"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="367"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="460"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="615"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="716"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1100"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1399"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="464"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="529"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="739"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="792"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="841"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1441"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1492"/>
            <end position="1506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1615" mass="176134" checksum="0E7D746B0C6E9745" modified="2025-10-08" version="1">MLSPRRQSLTTTDGSDCTADSERASDGAGFHLRGGGPKEREGQETPESRADTDDMLRDNSSPAEAPPSLEEGKKKKGKEVSIATGSPEVIDSQSIINQYRERLARDLERRELLARSPHLVDSETKRPSPIRQEMSTSPTPGSTSSSDLPTASTESNKTVRGGMTPSFTPGLAARTPSYPFPRMATPSYFPSALHRAFSNQSSIINAAGDQFDNFAMHDQLRSDPSTPASAMAFQPYGATPIQQDNFDFPTPNLYDLALMLTAEPGMDAWWSSVVQIMKEHFKAERMTLSIPADSTDLENVPWGQKATYNNLEGDGYSMGYMGRGSNSMVPSSRDDINEIPVKASLLEAQARHPQGRRHCPAVKVITPTPKRASPTSPRPQLNKEALEEHDAVEEQQPTSLPVWEAPLAIRPEVKGRVLPVLQGLDLEADPLIDHNGIQRVIERGKVIALTRSYPYLDAFTEEPTQEKRAPAVEEKKKPKKPTRASSSSKLSSLLGNAANPRVGSRVGKTATREKSKISNVMSVLDIDDEERRPPTPKYEEYEQTPPSPWSQSPAPSPAVRADPTENPFFTDATPPETIGVDNAWTVLHIPLKHILLSKPAPQTFRLDPAALEQKGGLRNRYDPSAEGNVFAERPSSADSRKKDQQSPIAILSILTPVIPYPSNLRYSLEHLAPHLATSFSLSRHYSNLETELAGVHRKRPTTSGFGALGPDGRPIADPLLFAHMPWPPSEDPSQRSITGSMTSPSDSGPSRSAAGSPGGNCAGDGYFASAPKSTAPAESGRSNKSSKELSLAAQSRSSSWRSVQPETSSIESDTGGQGIGRAEDTLQNVLKKKAASSNEAARQDSRGVQKDNDELVKQLAAQSLSDQTAHKHTRLHSYGAEFSSTFQSLPSGAMVQTPSVATPSAPSLQRQNTITTAQVSMLPPTDRLKGLMLDSLPAHVFVAMPVNGEIMWVNSKYLTYRGQTIADLVMDPWGSLHPEDRDMYLQQWTTALRTGDPFAHVVRIRRFDGVYRWHQARAKVAELRAARQEEVEASEAKHRLLANLIPQIIFTATEEDGITFANQQWLSYTGQAFDDAMGVGFMDYVHPDDLAKCRIPTEKFSSTPTKQAGPGTLSRNTSSSSSSTYDLPAGRLGELAKKQGIVKVATDSTGRLSYTAELRLRSKSGEYRWHLIRCVEIDTIDFGTGESSYFGSATDINDHKLLEEKLKEAMESKSRFLSNMSHEIRTPLIGISGMVSFLQDTVLNEEQRDYTNTIQTSANSLLMIINDILDLSKVDAGMMKLNFEWFHTRSLIEDVNELVSTMAIAKRLELNYVVEEDVPFWVKGDKVRIRQVLLNVIGNAIKFTAQGEVFSRCKVLVNPEPELGDAEIVLEFSIIDTGRGFTKEEAELIFKPFSQIDGSSTRQHGGSGLGLMDGTAEPGKGSTFTFSARFGLPTDTDHPDVVVTPPTETTSPPSEDSSTRTARPQALDKVAAGSQATSSPGSEVAVRSPTLDSSASSDPSVKSVPSQATARSSVSSVNVGLTHFSEAAKASGQDLSQMKLEMPSGRLSPSGSPTPGITNLAGPMDQFRPPMYSILIVCPQTYSREATAKHIEMTLPKDIPHQITALATVEERRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE82</accession>
    <name>A0ABR1XE82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor TFIID subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001593</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a component of both the DNA-binding general transcription initiation factor complex TFIID and the transcription coactivator SAGA complex. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription. SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription. At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B. SAGA interacts with DNA via upstream activating sequences (UASs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TAF10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675681.1">
        <property type="nucleotide sequence ID" value="XM_066805908.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038968"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07982">
        <property type="entry name" value="HFD_TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003923">
        <property type="entry name" value="TAF10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03540">
        <property type="entry name" value="TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017246">
        <property type="entry name" value="TFIID_TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="200" mass="20913" checksum="CD0F735CF9C2E88F" modified="2025-10-08" version="1">MASAPTENTNPVPASNNEAQAAEEEEEVNPEPQEAKMPTRRDISLKEFLNKMDDYAPIIPDAVTNYYMTRAGLPPPPQTDQRLARLLALATQKFIADIAADAYQYSRIRASNTSANNPMGNLGAAAGIPIPGQAAGGGGGGAAGGSKVDQSRGAPLGIQRAGYGGGGQGGSQNRTVLTMEDLGMAVGEYGVNVKRSEFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ09</accession>
    <name>A0ABR1UQ09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660422.1">
        <property type="nucleotide sequence ID" value="XM_066819537.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052597"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="entry name" value="formyl-coa transferase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050483">
        <property type="entry name" value="CoA-transferase_III_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207:SF3">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8061002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="391" mass="42486" checksum="53772E5A2E70577A" modified="2025-10-08" version="1">MAGKAPRSFTLLHGYRPSRLLASPPPVVTARRSFWTSSTRQQAIAAPICTRHLADLGARIIKIERPGAGDFARSYDSRVGPGLSSHFVWANRSKESLALDLKQPRDLSILRKLIADLPADVLVQNLAPGAADRLGLSYDSLKEKHPSLIVCDISGYGSTGPYRDKKAYDLLVQSEAGLLSTTGGADGKSPAKVGISIADIASGMYALTSIMGALMRRERDKTDPKTGCRIDISMLEAMVEWMSFPLYYTYQGQPGPRPMGAFHAAIYPYGPFETGGGGSVMLGVQNEREWTRLCAEVLHDAALAVDTRFATNLKRVENREALQHIMIRSFSQLSAEEVIARLDAAGIANAKVSDMQGVWEHPQLKARRRWTEVGTSQGARAGITSARSLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UR44</accession>
    <name>A0ABR1UR44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660567.1">
        <property type="nucleotide sequence ID" value="XM_066819682.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052742"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="1">
        <location>
            <begin position="52"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="586" mass="66930" checksum="D1B23F1CC826A1FE" modified="2025-10-08" version="1">MTLEWILDWLPFCRTKAMILSEWYCGMYPDIPPGVVISNDAFRQRTLLDVQRSLPKDWVATVTLEGRFLFEHEPSERTSWTHPDPNSYQQHLHEPVELPLPDFEPRYEALSYLWGSPENPRTVQVAQLAPGCLVDRIDYSMLSWTTVEVGQNLEAALRHLRLHDESRTLWIDALCINQEDEDEKSEQIVRMATIYRMASRVVVWLGPGNPSEQSTLAMSTLEHLGKQLELSQSTVRFASPTATESAWFRAVTPLPYPEETWFAIQALLSRPYFGRLWIMQEILLANSKTLVVCGRDEVTWYHFIRAIVCLVAKDSLPCSLRRPLEFVRALTWRFDQLSIPFIMNLARQKQCYIAKDRIYGVLGITPPEFTRSIKPDYKAEDRQVFMDAALACMNYDNRLTLLQDCEFPSPPDERGQRPSWVPDWSVPRVTRPLSAFVLSSGISRSCSTFIAPDMLQVKGRRLAVLGKVGPPTPTDPWEILCHIQDMEPRNLTTESYITGGSLLDAFLMILRLGYVDDRWPGHHLPTMAAWKKYFLDRLYSVNGVPSKSEVENSDGYFVTSILKGRSFVTTAQGYIGLAPAGARQGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT66</accession>
    <name>A0ABR1UT66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660727.1">
        <property type="nucleotide sequence ID" value="XM_066818539.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051599"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="504" mass="56244" checksum="718049648AB36923" modified="2025-10-08" version="1">MVAARLMSKPSVLRTLADEAKSRKKEARTEAPLPIDPRASANATEQPHGTPSGCYCRRPRRVRQRKQSQWGPLVAFDEIETLELHRPDCELSLFASGARNRKLGLAYTGMRAVASWAIACTFSAASGAGGHSIEPNFTYYPTVDRRKSPAFRAMRLMYHCVRYYSHYKRGEIQQRFFIDMCTRRISQLFRDRKANPLDVDSQNNSLISAFASLQRVSRLTPSDDFTLINHQASGCGPLSLAVLAQDEPRAKTILEASPSAIDENNILGLTPLRLALDNPALLRLLVSSATRAHLNNLSFHGGSLLSCAMEICSRKCHENPADTSSNNDRRPVDSVITLLEDDRTALQYDILQHGRHTPNEYCRHGFEEFAKQLKTRRERLKQIATPHLTENQWLDLGLDPTAVLDSHAQGVANELHAKGIIHSFEPYGVSRDLSYRSSVYHHIVGSEEADIFYGIGFRDVSVRDSNGNTPLALATTASAPFGLIDQYLDWLVDHGSDLRAPLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUC0</accession>
    <name>A0ABR1UUC0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661127.1">
        <property type="nucleotide sequence ID" value="XM_066818939.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051999"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="295" mass="32101" checksum="D7A385A8AF19CD6B" modified="2025-10-08" version="1">MKTAVALSEHVGLIKSPFPETTCLWYVRPRHQGSRAHHQNSRAQSSTPRTFALRFSFLFNLSGLDVLQLHRELLLLDLHALSRLLSQCVVLKLQSKDLSFGMAQLHLEIAVFVQLLANVIGFHVELALKILDMVRLDQALLFIGLRLGNLISPMTLASVFEVALELLVLLFDADGAITLFGELAGTSLLIGGGGLLVLPGQTLGFDILLLHSLMQNEELLLGGLGKDTFLLGYHLLPRDAVLVGDGEGIGLTLFALIVALFDGEVGLFIKALSLEPVVEVLRMSWLGRVVSGELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUW5</accession>
    <name>A0ABR1UUW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661314.1">
        <property type="nucleotide sequence ID" value="XM_066819126.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052186"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF125">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="3">
        <location>
            <begin position="53"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="476" mass="55358" checksum="4A719CE3BF4F7A58" modified="2025-10-08" version="1">MGTRLEARNAAPAPRKANPPRLGLPSPAPRRPFRPKATSSSSASSRKNQRPTAWLDGLRGFAALLVYWHHHELWAHESKGQRRFEHGFAYEGNYHFAALPFFRIFFTGGHFAVSVFFVISGYVLSAKPLGLIHDREYVKLGDNVASALFRRWLRLYLPFIATTFVYLSCWHALDLWIYDRTPQRTWVDEVWNWYIEFKNFSFVFNMGGLPWFSYNFHLWSIPVEMKGSIVIYTCLLAFSRCSKNARLWCCAALIFYFMYITDAWYCAMFVSGMLICDLDLLAKKQRLPPFLSRLGSAKKFIYYHLLAAAFRRRTETLCCCAKMRGWYYLSFLKPQAFFDCKWFYLFWAASLLVASTPRVAWLKSFFETGFCQYLGRISYSLYLVHGPVLWTLGDRVYTAVGWHQEAQLTNLPHWVDKVKLPKAGPLGLEVSFLLPQLILLPLTIWLAEVVTRVIDEPSVKFAQWLYSKTVPRSDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVJ5</accession>
    <name>A0ABR1UVJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661541.1">
        <property type="nucleotide sequence ID" value="XM_066819353.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052413"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="42"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="375" mass="40245" checksum="01D186C1D4A03702" modified="2025-10-08" version="1">MQQQCESTTLNGPSGGLEVLYSLPIEDASILESEPANLKPPLLFIHGTFCSAHDFMNFLPYLAQHGYPAYALSLRGHGASQKQRWLRKMFFTNLHSWAADVRCVLAHMAKEAATSRMSVSSPTSSAASSASSASIGSAASTTPSTNSASSLSSFCSRRRRPPPVLLGHSLGGGVLQWMLSSGAIGRHHQQASEISGLVLLGSLPLSGSGREVLSNWERAEASRGALHRPFILSERCLVRTRTQARAAFFSDETEDAVVDTWLRTCKTKHESAMAGMSVLWPFGEAGKVLGSLSGLGGARKVLCVAGSVDKLVPPAMVLSNAYAYAAAVKEAGEDLETCRMWTVRGSGHHLMMDAHWRECADGMLRWLGGEELPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVS4</accession>
    <name>A0ABR1UVS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661596.1">
        <property type="nucleotide sequence ID" value="XM_066819408.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052468"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046184456" evidence="2">
        <location>
            <begin position="25"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="458" mass="51650" checksum="633D473EECE3BA3A" modified="2025-10-08" version="1">MVTLTPTFPTLWCTILLLFPVFSSQDARKGVPGCEFRSDFVKRLTPVHFDPTQNCGELNFILQAVNKNRKYDYCSADPQHVLGYIRDGFRPAHGGDKKKMPQDCEIEQWWFKGHYPRSPVAFCKNATAIAATRDKKVRFNLTRAQPFFNVIHGPRTTCHDLVRNDLETIGNPDVAGPGLLLCAFFSGFYRDDRSPRRAELSFSAFYTTTMMLALSIAVASAVTFAETRATPSSIRSDLRLPNIYEYRLLALAPAFAVLPVMVAHTLHHERQQQQQQQQQKRGVFSVAQRGKSRRKLLLLLPRVLPALVCLLCVVMVWVIWVVGEQGRKSPVRFVFGGRLDIRVSGFLYTQAGEYTLAVVCLTTALPVLGILLSTWIPHRGVYYWRQAGSVFRVVCLLLALVEWIMLMFIRTKAVEDGQGHTSETEIGFGQILALFTWFPVLFILAFGVEFPGLDGAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UX47</accession>
    <name>A0ABR1UX47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661214.1">
        <property type="nucleotide sequence ID" value="XM_066819026.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052086"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="19823" checksum="A100E4F7F973425B" modified="2025-10-08" version="1">MASTPDPCPFLPKDHAITTIHGDGDLLLKVGTTRCSTKLHSSSSDQCDHLHDVAHTFRVCSQAMARASPVWKRMLFGGFAESKPPKEGVDWTVALPDDSPEAMLTVLGMVHARFDLIPRFEYGPPLQKVYDITIMTDKYDMTHIVRPWALAWLNTASGGMKNDFQSHLELLWVSWGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UX77</accession>
    <name>A0ABR1UX77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase family 69 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014742</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661244.1">
        <property type="nucleotide sequence ID" value="XM_066819056.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052116"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021047">
        <property type="entry name" value="Mannosyltransferase_CMT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144:SF8">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 69 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11735">
        <property type="entry name" value="CAP59_mtransfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="552" mass="62296" checksum="8092CB0BA3443EC7" modified="2025-10-08" version="1">MRHFASSSERQPFVDPADQTLSPASSTTLGDFDYAEDVEKDSWQDRLASAGGRGGQSWNSWFRSRQRGFRRILRRHPGHPLFTVLKYTILLICILIIGTPILAPSYTRQPKHYRDLAARCQGPGPSAEPGCANPFKEKVFISVSLYDKDGHLATGSWGRTLLELVRLIGEDNVFVSIYENDSGEAGEKALNWLKSQLRCRHKVVYDPHVSLSDFPTIRMPDGTDRIKRLAYLSEMRNRPLRPLDQLDENEDGGVVEYDKILFLNDVAFHPIDAAQLLFSTNQGPDGRTRYLSTCGMDFANPLLFYDLYAQRDAEGFSNGLPIFPYFSNAGAGLSRAAVLRQADAVPVTACWGGIVAMQARHVQNLNQSLPDPDFRAPGHHVLDPAQPASVTSPVRFRYEPEVFYDACECCLFLADVAQVARKASGKTEKELGTYVNPYVRVAYSQETLAWLPWVRRWERLLSVLQRILTPILRLPTHNPHRAVREGESFMEEVWVNNEGSQGGHWQLTQRVARNGLQCGVREMQLVQQGERTNDVNWQNTKMPPGQVLHFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UX90</accession>
    <name>A0ABR1UX90_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CAMK protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014757</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661259.1">
        <property type="nucleotide sequence ID" value="XM_066819071.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052131"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="392"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="96"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="345"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="712" mass="78116" checksum="D0D41DC2A9919298" modified="2025-10-08" version="1">MSNTTRPPPPPQTLPHAAHAFVRGNERQRLPTPGSLPLLDTSNAPTTPTRPSKDTAAYLNHQSLLANQAIQLSPHSFHHDVSSHRPDQAISADDTMNSQLPVRPGQIQFRSNTISPSPPTETIAEETTASPTDGALHPSTPLGPRSIDSLSLNTDFPSQTPSRADSLNSNYGLSSSHRLGHKSSSASLRPVSRTPSVKRAFANNIGSACSSAVPSPVIAAMGDLTPLPSPLLLGDSPGPWRRLGARPPSREANLPTIMPDSVLVTSSGESVAAHLANQSKRKVYGGLRAGDPPANSISSSGDKMHGRNRSVSEYIPDPMRAQQQQQWRWRSQPTSRTPSLRFAWINGRCKPPTPPPSESSQSNDGSAGRLSKKPRFEYFEARGKEDNKLRRWRAVKQLGEGTFSRVMLATSQVAVDDSEEDGPVCEHGPRGGASEQRIEMSLKRELEIMRSINHPSIVHLKAWNIEPTRALLVLSYCPGGDLFDVATTHRDLLSPSLLRRIFAELVGAVRYLHDRRIVHRDIKLENVLVNIPAHELASPNHDWQTYPDSIITLTDLGLSRFVADDEKLETRCGSDDYAAPEVILGQPYDGRAIDAWSMGVLLYSLLESRLPFDPPPGASDAHRMRSRTSHRIARVEWRWIEYAGEDGDHDGDEAKFEAKGLKGAMEVTEGLLKRARSRWTIDKVAANEWVRGGIQVGGGPHFRQEEEGVEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXK2</accession>
    <name>A0ABR1UXK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014651</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661153.1">
        <property type="nucleotide sequence ID" value="XM_066818965.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052025"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF164">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="507"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="545" mass="59894" checksum="8D9DE5BA29C52FF0" modified="2025-10-08" version="1">MDDTKLKPSADHVEEFDAVKDSDVLRGEVEVMGTVKLTHGKTIYIPTPTADPQDPLNMSLWQKYVVLIVISIFSCLGLSLISGFGGLLGFYIPDYSAAGKGYADITHLMTYPTLFMGIGNLFGMPLAYAVGRRSVLLVSTVIMILAAGVAAGAKNFEWHLAARMVLGLAAGQSEALVPMITQEVFFLHERSRGLMIQQTIQVILTAIWTVFAGPIAGAITPQWWYGLGAILAGVQFLLAVFFVPETKYYRPMSSFQESTSTDNNNKDNAAATPSSDDHGSSVMGAANTMCTERPPLDYVNFAPRTWRSDMRLWVGDIEWRKGWEAFYQTFELVLYPNVFWALCINGLTLGVNVAIGTTPPYNFPQTSASYVNTGQIATALLALPLFGHGSDGLIRWFSRRRGGMHEPETRLVPLIFPMIVGVFTAVLYGQGAAHPERYHWFVYVWGVAAYYFCFVGANIVAITYLLDSYPTRAGPLLIIICAFRGIISFGVSYGITPFIETAGWDGAFGAFGAMTAFFGLLGIPIYVWGKQIRQFTGRFAKDKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UY65</accession>
    <name>A0ABR1UY65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BAG domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661348.1">
        <property type="nucleotide sequence ID" value="XM_066819160.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052220"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="2">
        <location>
            <begin position="313"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="383" mass="42352" checksum="F3EE915D324F511A" modified="2025-10-08" version="1">MSWAYMWYQNPTYVDATISQLSEALAGSNEYIAAQGISPTVLYSTLACAALAIPIGMSRLPGWPSGRDGLSPFGSQSDGVPRVTDDDFSYITSEDLEHSLRSPSRTYDPHGRNPPASADIEDDILLIKHKGVTYPVHFPAYSIGDGKLYVHDVRERVAWLMKISEQRSQRIKMLYKGRNLKVDPSQPIPVREYGVKNNSEILVVLPEGNESDDDSSESEEIIVTDPRDEQKPKKSKKSKKGGKKKKVKSPRDSNANLDIPNSAEAERRSSADGSKIPSRVSSPAVPAGPMEKLDSISSHFSTKFLPLCVEFSANPPKDDKKCVDEHRKLSESIMQQVLLELDGVDTGGDPDVRARRKQLVNQVHDVLKGIDEHLPEGATKSNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V496</accession>
    <name>A0ABR1V496_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662746.1">
        <property type="nucleotide sequence ID" value="XM_066817054.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050114"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="472"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="638" mass="69387" checksum="557564A1A76B59BA" modified="2025-10-08" version="1">MSDAGGNPASNSNDSPAAAKPGAPKDRSCPYCAQPFTSSSLGRHLDLYIKEKNPKPPDGLHDVDAIRKMRGTITRRQPRGSLARRDASTPSTPTGSTATAPRKSSAHEAHAQRPSIPKEGQYFVDQAPKWPLPPSWEATGVMNDLPARNGDLQAGPWDEADPTRKQSLQPQRVPSRAAQKQQLDARQKLTDAVDTARAAELALREMLSSWRAAKQHIDMNSVPFDFDPLALDFPALTLQCLQAPPTLFSSTPHPTSTSWSIQPPAQKQFEALKTWFQEEFRQWKVACAAATTASSDDLTYPPSQTHAPLDLRESVKKAEKAAANLEKQVSEHLQSTYAVWEQLTAQRRSELWTLELARSVGRRQKEVDKFKESQHYLRQENVNLKSQIDQLNHLQQPREFRVMPPATVPFNPSIVSYCLEGPQAVGLNLDDRHVDLTTLVSRAIERWKNVIVSSRGSGMSSQRPLEQPTPTPAAAAANAATPDSPAMTQPKPAAAVPAQPRHAAPASGVTPSNEVRATTTPTTTTSAASAANDENSDQDADAEMEEDDFPMSTSTPLVAKPQQQLEVPRTRRLGGGTEDRFAVDGLATQTADMGRSLQSLNTATQGSNQRARNTTNKTGYSAPVQGVSAGGGDPMYMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4F8</accession>
    <name>A0ABR1V4F8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL46</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012544</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL46 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662550.1">
        <property type="nucleotide sequence ID" value="XM_066816858.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049918"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04661">
        <property type="entry name" value="NUDIX_MRP_L46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040008">
        <property type="entry name" value="Ribosomal_mL46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021757">
        <property type="entry name" value="Ribosomal_mL46_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033650">
        <property type="entry name" value="Ribosomal_mL46_NUDIX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11788">
        <property type="entry name" value="MRP-L46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL46 N-terminal" evidence="8">
        <location>
            <begin position="68"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="343" mass="39178" checksum="AB3CC6921ACBACB7" modified="2025-10-08" version="1">MASSARSSGAAAALLRRRPNVCASCRTTQFLRPYSVAAEAQATAEAHHLKPTQSEPHVPFTVSRKAEYRIRSSIILSRAPLLTRPLTPFENAFFFYQKRLNERLTTEFRHSMFFKKDTAADLDWRIKLEERGGLVAKELGRYYAKGRNAWNDELLVGSTLSDENRIRETLLKDAEMRVTEDGEKAKPDEIVPVEKPQPRITESDKKNDVRKLDRKLDQTLYLVVQKASGEWQFPTDDMSTEENLHQSAQRVLDAAAGPNMNTWIVGRVPVAHHVVQPKFKEDTSLAAKGEKTFFLKGRIMAGQADVKENTLGYKDFKWLTKDELKELFPTPYFKSVRNMMADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4I5</accession>
    <name>A0ABR1V4I5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase-like 2</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cyclophilin-60</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Cyclophilin-like protein Cyp-60</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">RING-type E3 ubiquitin transferase isomerase-like 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_012851</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662857.1">
        <property type="nucleotide sequence ID" value="XM_066817165.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050225"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01923">
        <property type="entry name" value="cyclophilin_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16663">
        <property type="entry name" value="RING-Ubox_PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026951">
        <property type="entry name" value="PPIL2_U-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF1">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="U-box" evidence="14">
        <location>
            <begin position="37"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="13">
        <location>
            <begin position="327"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="487"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="550"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8066104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="579" mass="64427" checksum="8DB85A1325FD37CE" modified="2025-10-08" version="1">MGKGTDKLYITHSEWSSSDAFSANTGARSKATGASFKRLPFNFCAASLQPFQNAVCTTDGTIFDIEVISKWLKDHDTNPVDGKPLAMRDLIKLNFARNADVDSRGQDGSGSDGKGDLIDPVTFKVFTDNTRIVAIRHGGYANVFAWDTVEKMNIKSKMWRDLVDDKEFGRSDIITLQDPQNAASRDLSQFKFLKEGGEAILTKEQETERKEGNVNIDALGRVGDKVLRAKEAVEKARREREAGGDINHTHSKALTKNSDGSTAMRKSMIQDKKTAYNAAAYTTGRAAASFTSTGLTPETSGERALLTDEEYMLKPRRVKIKGYARMETNLGDLNLELHTEYAPRAVWNFTRLAQKGYYRNMSFHRNIRNFMIQGGDPSGTGRGGESIWGKNFKDEFESPLTHDARGVISMANKGKNTNSSQFFITYRPVKHLDNKHTIFAKVVGGMEVLKRMEEVPGDGSDRPLNKITIKDIIVYLDPFEEFQKQKADRDLQAERKAEVERRGGTEDDRTTWTGKRIRGNGTADSGSGGPGVGKYLQAARKQHQNTGADELIEDDVPDTWEEPARKKAKSGGFGNFDAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5J8</accession>
    <name>A0ABR1V5J8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663211.1">
        <property type="nucleotide sequence ID" value="XM_066817519.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050579"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="397" mass="42511" checksum="2D0B8375F19748DF" modified="2025-10-08" version="1">MSLTFAGAKDLKKAKVKPQGKLAMKLWSLLQKQKEVVQADEAEAKDVSSISTSTTEESYRRSLLITVPVGEVPNRYFKSNAGGTLSPQELMHLNVLVHPALAQQNISLVDALQSGLLIPKGPVTAANLVSPDSGYEPGSDQNSDERLSGEGRRSSEEKPASGDGPANEEGDAILELVDQSKLVLVAEEPGITTSAGTVDDLAQDEDVDLEELYSILPTTPDQDPSASMEDQDQSETPLPESPTIPHAVMLQRFAEPDDCPPSPGPPPKRPPPKEPASPAKSHERVADSHRILQSPFTGFSEHRYEAGSSRSSNKDYGSLGKREGGGLSSQLHSPVLPPQVSVGPSTPTRRPLVIPMPALPAHMRVALSQPESPEPEDSQSSVEDLLTEARRIASDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5T0</accession>
    <name>A0ABR1V5T0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662399.1">
        <property type="nucleotide sequence ID" value="XM_066816707.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049767"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="424" mass="47177" checksum="26041A22B9B0165A" modified="2025-10-08" version="1">MEWRSSGHAAAYGPPQMMTHSPLSGPPVDYFSNNARPVDTLAARFSRQGEPRPRSSLGFHGGPPSAYDDYEPSQIIETPPPMRHASLARRPKKSQDDRTRMPPPARPQTTKPERLVFRPPPPANHRKSAHFADDDELDDDAETEDGFYQPAPGRQDSFEYGNAVVPSRPRRTSIDSEDYEDSVFPLDEPTGHNRRHSSYNFEDKVKQAASYQNEVSGGTAPLTAETLRRVKDGGTSRSSRSTQSRDESSYKQSATTRTTRSSSGDDDITIKVPDGAIVEVGNAKISCRMGGEINIGRNNSGSDRGTVYEDDRKSRAIEDRKSRAIEDRNSRAIEDRNSRAIEDRKSRAIEDRKSRAIEDRKSRTDKPATRNRASSQSGSYSHAPYLGGHGGYAPAFGSHYGSPGHYAPPQYPQYPSSEYEYYET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5X9</accession>
    <name>A0ABR1V5X9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013344</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663350.1">
        <property type="nucleotide sequence ID" value="XM_066817658.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050718"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="3">
        <location>
            <begin position="12"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="420" mass="46151" checksum="6C821AB523AF1CAD" modified="2025-10-08" version="1">MAPRQNQRQYNIVVFGATGYTGFMTAEHIAERLPTDLKWAVAGRSEEKLKRVVSECQKLNPDRVQPEIEVCNLNDQDLLALAKKTSAMICTVGPFAQFGEHAFKACAEAGTHYIDCTGEVVWTLSMIQKYETLAKKAGIVMIPQCGFDSAPSDLLTWSMAQLVRSKLSAPVSDVVVSIHDLKTKPSGGTLATIIGLVETYSLKEIGAAKAPFALSPVPNSYQGPKPSLFTKLTGLRTVSHLGLLTTSVTAATDEPIVQRTWGLLQQERSRQKEAYGPRFNYHEYARAKSTLSGMIAHYGLVIGMTMLVLFAPVRNLMRRYIFQPGEGVSKEEAAKEYIVMRGTAVPDVQPKSDKMAMIEAKYPASPYLLTATCLAQAAYFVLKEDHQLEGGVYTPACLGQRFIDRLDGEGFKIETKLVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V719</accession>
    <name>A0ABR1V719_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663740.1">
        <property type="nucleotide sequence ID" value="XM_066818048.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051108"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="362" mass="40507" checksum="EDEF13A02F06D443" modified="2025-10-08" version="1">MMQSLMGGIPSHAPQFYAANTVADEYTRQLMMAESARQSYRASNGYRPTNAMRVTKPGSASTSPQSMMARRRTLVNDNNIAKRRQYALQQMQMAESSYESYQEPPKRSSRPVSWHPSTQFQQPQMVMYQQCPPQQLDYSQYFMPAPTQYTEADIYAAYQQLPPTPAIYSGHTSPVATLSPVSLPFTTTAQEHVPPQYVTASDTWAAPTHFNTTQYGSSYGSSYESNGSPDTTEPFPSYTGQSTFTWDAGSSAEYLPATTPPTPETFQPVAQPEPVVPVEEPSLYQAEEESEEEGEILIGMGLYDTPDKSDMDPQLDHYRTTTSDLLGSTYRKGAGLKLEEAWEPPKEEEEDEEEDAESEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8B1</accession>
    <name>A0ABR1V8B1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664156.1">
        <property type="nucleotide sequence ID" value="XM_066818464.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051524"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.350.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032382">
        <property type="entry name" value="AltA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16541">
        <property type="entry name" value="AltA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51895">
        <property type="entry name" value="AA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046459855" description="AA1-like domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="AA1-like" evidence="7">
        <location>
            <begin position="26"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8067403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="160" mass="16981" checksum="A0B0E0EEE90FEA26" modified="2025-10-08" version="1">MQFTFATVAVALFGAAIAAPAPQANETKESVQITKFHARKNHLNGGLTGPVDSIDFNIVSSVEAGTMAFVCTASAAEGEDSLKLKPNSYRCNGGDDNHHYSFELNSAVGEDDKFSLAIIHQTGIAFGYWATVEIPTYCHAGGAETMVCQQIADVTANLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8C9</accession>
    <name>A0ABR1V8C9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663072.1">
        <property type="nucleotide sequence ID" value="XM_066817380.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050440"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018830">
        <property type="entry name" value="DUF2434"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10361">
        <property type="entry name" value="DUF2434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="510" mass="58195" checksum="1D877394AB926EBC" modified="2025-10-08" version="1">MPVIDVRDIMSWPAGDNATDTVFGNVHFNLTLLEHWNYTLYSNNTLSNGTKCILTFGPYPPTLLFPNGTFINSTSCYSAIDPVGIRGGVGIAFAVLYAISLVFICINLTKHGKRYLPATKRFYPLGRRWQWYWGLFVCGAAVIGLFTGVDIPIVLNNFFWYLMQLGSMALVWEAVRHWGSWMERQFIDPNPFVLQQSDKRGMFEFWLPLFFYFWLWINFFLVIPRNWGNIEKQRDFDQTRLIAEPSATDIRFKIATFCLLICWLTIMTSMWHSIRHYEPRNRGLFNRAIGFLGYMPFRFVLLLPLALAVVAYQGLCAWEFWLSPQKVDTNVIAMYVGGYLPTFLILWVQIISGFMRPNEDKNLIQQRRQRGDAIDRDLGIVKKPAWWRRVNGDMPVEGMRDRLMRNVREVGGGAATARNVELAAETRARESDQAQAAAERERAAGAAPIEMNEIRRANSIASSMRTSTAPPPYEPPYSGKSANRRSERAMQAAAGLLFPNAAPPPPPFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8G5</accession>
    <name>A0ABR1V8G5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663313.1">
        <property type="nucleotide sequence ID" value="XM_066817621.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050681"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="95" mass="9684" checksum="670E7875CF693ACA" modified="2025-10-08" version="1">MSSRLFLASSGRGANAIRTTVEAPMLLGFGPSSLSSGTTTPGAGAGAAAFVGRTPLLKLARRSLHTPCPLPAEAAAATRRPAPWHHTGHHTSSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9U2</accession>
    <name>A0ABR1V9U2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663476.1">
        <property type="nucleotide sequence ID" value="XM_066817784.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050844"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="518" mass="60053" checksum="E91270068D487868" modified="2025-10-08" version="1">MSNPTSPQASLDASSSTHSSSRQYNPPSFLGIPRELRDHIYGYLVTVDQHFDYEDRNEYNGVDLQDLAITRVNRQIRAESLDCLVKKNHWVSVTHVDMDEGCVGFDEHSPRGYWSHQPWFSCAPFLDDRLRSQNPSTISDGRTCIFAYHPLAYWLFVQDIMRKVHDDARVIVQALPSTSLSGSSFSNLVEPLRYLRDLSSPYPPGSENNANLLTLSSRTMRLLHRISDLITMKQCFQHQGRNAELNGRFSDAMCHFWLGKLYSNYEEYFSKSGTREWNSMVYLETELAIGFSRCVHKYLTKLSKYTSYENMVDNKTPNIFAKSVRAAHQTFDYPVIIDSQRREAHLYRAFAFFHYGQYLDCLPSLARYMTYRSRDMDVLYLVDTDWDDCGFDVCGDSFCVHAAEVLFYAQQIDPSQDLLAGLDADDRAICRKIQQRPGPQAFPLAEHPIPLLGTWVGDPRIWEEYTEPERVLLKLFRQRCEEMSDGDAVDERELEAQYAREGIRWYYDEDFGLSLRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9X2</accession>
    <name>A0ABR1V9X2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleosome assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013833</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663839.1">
        <property type="nucleotide sequence ID" value="XM_066818147.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051207"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="220"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="289"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8067086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="37936" checksum="27EA92D578643E35" modified="2025-10-08" version="1">MAAPITEETLKVSYEQLTDLEKEFEENEVEIIRQQVALNKPLYEKRAKILSQLNGFWALVLEQAPPEVDQYIQPSDSAVLLSSLKDLTVSHFEIENGGKGDPRSISIKLEFNENDYFEDTVLEKKFWYRHAKSGWAGLVSEPVPIKWKKPGKDLTQGLLDLVVKVWEEDKKRGPSKGPITKAKDYTPAQKELKKKIETVGMGGVSFFGWFGFRGFPISEEESRTATEKEKENRRLRAEGKPVPDDEEEEEDDEDEDDDPYGLEIFPDGDELAIAISEDLWPSAIKYFTSAQEQGDMSDIDFEDGMDDDDEDEEDEEEEEAAVSKEPPAKKRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGQ7</accession>
    <name>A0ABR1VGQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664232.1">
        <property type="nucleotide sequence ID" value="XM_066814942.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048002"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="12719" checksum="497B3617E9EAF2C5" modified="2025-10-08" version="1">MFPASMPTKCLAVPVLAATPTQPGQHGGQCSPHYPMPPVRRRLAEVPWCAKGPKIVQQGSTSDGVANEPRNPPPAFESVVTDQQAAAATANNNFAQGGDNRHHIAARRARAPSTTTTDDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHM3</accession>
    <name>A0ABR1VHM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_010850</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664455.1">
        <property type="nucleotide sequence ID" value="XM_066815165.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048225"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050794">
        <property type="entry name" value="CPA2_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468">
        <property type="entry name" value="CATION/H + ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468:SF0">
        <property type="entry name" value="K(+)_H(+) ANTIPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="9">
        <location>
            <begin position="42"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8070647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="848" mass="91306" checksum="ABF613982120C62B" modified="2025-10-08" version="1">MNSTGDGNRAPSQGGVLEGSNPSHYNPTDPLTIFIIQAGLILILCHLLHWPLSKIRQPRVIAEVIGGILLGPSVMGRIPGFKNAIFPDASIPNLTLVANIGLVLYLFSIGLETDVPFLLKNWRVATSVAVGGLVLPFAVGCGLAWGIYHQFANEPGVQPIAFSTYMLFVGVAIAITPQAFPVLCRILTELKLLETSVGVITLSAGVANDVVGWVLLALCVALANAGTGLTALWILLCCLGYMLFLMYAVKPVLTWILRRTGNIDNGPSQSAIGLVLLVALGSAFFTAIIGVHAIFGGFMVGLILPRERNFNVKVIEKLEDLIGAILLPLYFTLSGLKTNIGLLDNGITWGYVFAVTFSAFFTKILGATLASRLNGMVWRESLTIGALMSCKGLVELIVLNIGLQAKILSTRTFTIFVVMALLTTFATTPLVSWLYPPWYQKKIAAWKRGEIDWDTGATLSHLATANRSTLNMGAGMSRVNSMLVYLRLDNMPDTLNLLYLFGMGNDAKKETTEAIDSKEAKSSVTPVNKKTVRTHGMRLLQLGDRDSNVLTASQVDDYTRNDSVVNIFRTVGQFLKIAVSGEVAVMPQHRFAEALLAKASDTTSDLLLVPWTGTGAISDSSTETADDKVLSASYLQFASTLLASNDHNIALFLPHNPKRMLPNEEPSAKRLELTRAQSFKSLPQQGGIPSIPVMDKSYHIFFPFFGGADDEVALSLVIQLCEASHTTATIMQFTDSSAAGLDVASVVSSKHRDTGKITVDKFHADKGAEAALSRALSEVRKDDNDGSRGKTSWYNLVVLGRSHHEAEGSSSSGSDTDARHCLGDTAATFIASSDLNANILVVQARSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHY7</accession>
    <name>A0ABR1VHY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Urea transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011061</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664666.1">
        <property type="nucleotide sequence ID" value="XM_066815376.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048436"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050277">
        <property type="entry name" value="Sodium:Solute_Symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086:SF10">
        <property type="entry name" value="AGR155CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086">
        <property type="entry name" value="SODIUM/PROLINE SYMPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="456"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8070858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="52606" checksum="B75E6662AB86D37C" modified="2025-10-08" version="1">MSTAFPLALNFIAAAMGSGILFSYPQLATLAGLQGVIVYALSSALPLLVFAALGPVIRKKCPEGFVLTEWTRQRYGIITMLYLSFLTLVTLFLYMVAELSAIGQVVTALTGVNELPVIIVECVVTTIYTSIGGFRISFLTDNVQGVMIMLLIIIATITIGVKTEIKPELIESSGLLEPNLLGWQLLYMFPVAVLTNDFFLSNFWLRTFASKTDKDLWIGISIAMVVILIVLTLVGCTGLIAAWSGAWPGEPAQDGSVAFFLLLEQLPNWVVGIILVLAVTMSTAAFDSLQSAMVSTASNDLFRNRLNIWWIRGAVVAVFAPVVVIAIKAPSILQIYLISDLLSAATIPVLVLGLMDRFYWWRGFEVLVGGLGGILTVFIFGAIYYGDAQKGAELILLEQGLYTSDWGAFGAFVAAPFGGLIWGFIALGARLSFQYLMAKKNGHRFDALDRPLIASGSRSDPDDDTNSVNVQREEVGVSKSTGKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI04</accession>
    <name>A0ABR1VI04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_011050</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664655.1">
        <property type="nucleotide sequence ID" value="XM_066815365.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048425"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051380">
        <property type="entry name" value="pH-response_reg_palI/RIM9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013:SF3">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046971501" evidence="7">
        <location>
            <begin position="26"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="208"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="486"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="310"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="558"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="600"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="651"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8070847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="663" mass="69775" checksum="4E95510EC67618EC" modified="2025-10-08" version="1">MLRPATPLTILLLAAFAMLTLSVLSTPIIKAIPLGTFKGTSFGVFGWCRGDTCSGIEIGYDASAIEAAKSGDFDLPNSARSTLSAILIIHPVAALFTLIMLIMAGIAHMHSPSHSSRYLLALFIFGILTFLVCLLAFLIDVLLFVPHMAWGSYIVLASTVLVALSGLVSCAMRRTVVSRKARKKRIAENAEMSGENYYNRTAQQPVATTTPASMQPTVPVVSGGNGPSDKLPSFATYEGKDDRSSDERIPLTSASPSQRSPNNPHVDMQAPPNAVYGSGPQRSASNQSLPKDQTHEFQRARWWPPPVGARGRGGYGRGGYGYGPPAGGRGGYGGPGPGRGGYGPGPNGRGGYGPPRGGYGAGMRGGRGPPPPNYGGNGGFDRRPPPGDAYGAYGPARNGSPAPGVPYGMNPSMPSASTGNTGTGGFEAYNPDRVRPVGRAVEMDATTGSPGQAPPGFGQFNGIRDSDADVAGMLALQQARVQRHDTFMSEASRYSQDEQYPPPRQAWNQGPGRNSPRMPSPLNVGPRAAELASQTPPPTAPAASDSGNYYEDVDPRFTEPPPRALQPGPAPLRDPMREPSYDDDMQTAAGPKSPVPSERSVFTSVSQRPINPRYQPPAGFGQMPPRKPANQNEVDVLNNPDFQLGPSRRPGGAGMPGGAYPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI54</accession>
    <name>A0ABR1VI54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664375.1">
        <property type="nucleotide sequence ID" value="XM_066815085.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048145"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="15654" checksum="971E70C90D6EABA4" modified="2025-10-08" version="1">MTPELERVLARGRDMHPTFPDDVQLALGTFGVLNPKYTESINLPDLGDKRGILQYVGLNDAMIDWALEKYHADFPSDPEELAVKFNEMNGDIPTEGYRFPLLDRFNTILVDRGVQEIEELDISYGESSYQHKIESFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIV6</accession>
    <name>A0ABR1VIV6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011376</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664981.1">
        <property type="nucleotide sequence ID" value="XM_066815691.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048751"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8071173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="493" mass="54030" checksum="81098A7306003EF9" modified="2025-10-08" version="1">MSPEPKKRRTSPSPSPRPSKAPFPHVNAAYDEALDKYGPVVVVPRHGRRDHVIDHRYIRQALVEDPGSFSFEKGAAELLNLGFISLDNTAYIHDIHNLVAKNVQPRLSGIVEHLAPAIQTQLDRIETADGTTIGGSGSNEEKKSWVECPDLFDQIQLAVAQAMVVLILGESHAANPTMAKHFAAVAVGMADLAGTHESTHAWSRLPRLWAFWNALTAAALIILPTILFGIAPALWKTRHAHLANGLAAAQQKQRQGDFTPLFDVALAQHCGGQSSGLAALSGFLHCLTLCVSIIWASVHQTVVAAVWTLVRLVQEQDEYLPAIRREWESVFDGDGDGDERRLSAKKLSQLVLLDSFIREVMRTRGDTLGCVRQTTRPVQVGPYVIPAKAMCMMPISRAQQHPDNYGTTGGVFDGFQWQKLGRQATQVGPDFLTFGLGKWACPGRQLAVHDIKIVLYALLSRFDIRLSKNTFLIPNTINTASVAPVAILQLKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJE9</accession>
    <name>A0ABR1VJE9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cvnh domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665148.1">
        <property type="nucleotide sequence ID" value="XM_066815858.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048918"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046381092" evidence="1">
        <location>
            <begin position="17"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanovirin-N" evidence="2">
        <location>
            <begin position="31"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="157" mass="16957" checksum="FF1E0DAAFF43BE95" modified="2025-10-08" version="1">MKLLAVVSVLIGITAANNWSLRCYDEVFVASTGLLTANCDTGDGKGTLHTSSLNLNTCYGWDGETIVVSGLRDRTASFSPPPIAKRNGNYGNFCTDCSLNKIQDPIWPKLSPYLNCTCGDPPVDAAVNTGKGYYYHPLVRRVNLIADTSCGHLLPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJJ2</accession>
    <name>A0ABR1VJJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Beta-xylanase</fullName>
            <ecNumber evidence="10">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_011510</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665115.1">
        <property type="nucleotide sequence ID" value="XM_066815825.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048885"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF35">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="GH10" evidence="11">
        <location>
            <begin position="1"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8071307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="313" mass="35098" checksum="1E41FAAB68567D10" modified="2025-10-08" version="1">MSSADHTILVSVANITKWLFTEPEQGVFNFTEGDIVTSIAQEHGLIQRCHALVWHSQLAPWVDNATAEWTPEALSAVIVEHVTKVMEQYRGKCYAWDVVNEALDEDGTYRDSVFYRVLGEDFIKIAFRTAAKVEPGVKLYYNDYNIEKPSPKSEGVLRIVRMLQDDGIKIDGVGLQGHFVASRPPTLDEQIATINAYGALGVEVAYTELDVRQTTPVNETSLEWQANAYRDAVGACVQAEACIGVTIWDFYDPFSWVPYTFPGEGAALLWFEDFSKHPAYDAVIEAMKNGTVSPCKRRERRRAHIAARSAELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VN18</accession>
    <name>A0ABR1VN18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Capsule polysaccharide biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lcsJ thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665061.1">
        <property type="nucleotide sequence ID" value="XM_066815771.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048831"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051490">
        <property type="entry name" value="THEM6_lcsJ_thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475:SF4">
        <property type="entry name" value="PROTEIN THEM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="39361" checksum="67D7A421DC649122" modified="2025-10-08" version="1">MASSFGFMKPLSKIAKPVLLPAATASLAYGTYHGRQAVIDYLVRFFTGPGRTSRLIAVVLVLINWKSLPLAWTVRVWNTMIQHIFVRKLHTHTPDKLFHPAISSTHVSLLEVDYNLHKSNSTYFADLDVSRSHLASHLFARGCRLLADNEQTRLVMDPKHPDRPAKGRFGVMLGAVACNFKREIRPFAGYEMWTRVLSWDRKWLYMVTHFVEKGAVRPRSWAAEDFGLTADADGKHAEQDWEKKVYASAVSKYVFKIGRLTVHPAVIIGASGLLPERPDGWVSPAGSGMASPAEPVVGNTDGGARAEEQASGWDWVKTEAERAKGHAYAEHFAQLEDLHGAFCGGGQGALGHFSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT76</accession>
    <name>A0ABR1VT76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665357.1">
        <property type="nucleotide sequence ID" value="XM_066813395.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046455"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="106" mass="11816" checksum="AEF124F0B8AA4972" modified="2025-10-08" version="1">MAPFATSRPPTRSFRKTCVPTVRTANVSKVVTSPSGQAGFFRGQRLLHHKTFDEDESDGRDKFGDVSFFELLLWFCALASLLHVPYYADAELVGNVLLAIDPDDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUL5</accession>
    <name>A0ABR1VUL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665873.1">
        <property type="nucleotide sequence ID" value="XM_066813911.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046971"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="489"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="592" mass="65221" checksum="05EFE00CD95D933B" modified="2025-10-08" version="1">MPVTSYIAIQPQTLWNPSTKMLSTLVVDILLAIGALAFLILAASAAALQDRPVMQGIGPVVETAMKLGPTIFPILFAALIGRMLKNVGRYYVEKGLKLGTLWRLVNVRTMFDAAVNPVQFREISVVAMLLIVLWSLSPLGGQAVLRLVHHFNETSTETVPIRYLDLGPGGSLLVQYYYLNIFDGEVPVPIDYTFGSALLQNQKVRAGPRDNWGNVKIPRIERLDKSSADDEGWLDVPYRNQTSETYSSLMGIPIVGVPNQGTTNMASRCDDCEYDGMFGVLDPKIGRPSIFLGLRGLNETENRNASFTAPRRITFLSGAGRRSATPEERWPDDSRANVTASTTCAVTQSLVESKVRCEQGDCAVTAIRRFKTDFRNPDFTVFDQWAVVVLEQISKQFSRPPSLTQTSNLIEYFLNDTSTIPVYEVHETNASANETIVDLSQVPSPLLAERAAMVLNTACYPGDLKNPLFFGASTNAVVTHMSNVYKVDWAWVCILFLSATTLIVAGIIGIVLGVQAKAPDMFDPVIGLTYDNKHLDVAELRVANPLQVTERARLLSDVVVRLGDSQGAGTRGKIVFGTREEVGEMRRDKMYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUL9</accession>
    <name>A0ABR1VUL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin synthase regulatory factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665881.1">
        <property type="nucleotide sequence ID" value="XM_066813919.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046979"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF3">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="827"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="859" mass="93091" checksum="68D6EE725B9D745B" modified="2025-10-08" version="1">MAYPGAQRPYAGMAAQRPAPRGGGGAYPGPPRQQFDQYQDDYGYEGGFDDYNDGYGPPPGGNFGRGGPGGYPQDAYGPPPGGPGRGRPPPMGGRGGPMMRGGPRGGAPMPGPGRGYPPPGRGGRPGPPDRSVSSDPSMARQAPLMSPQERDFGGGSAYPVFPGQKRATDLDEESRILDSMQNMDLNGPGPGPGGNRPPQRRPTMESDYGGGYGGYQDDGYGAPMSPGRGDFGPPERSMTMPNNMQPPMGMRNGPMPARADSAPYAGPPGRGPQGHQLRKGIARHPKEWQFDQGYDYQAPPQQAWGNEPMVRASFGDFYDAYYNPRDSEYHPQGPPNDIPDFDAAPDHGPRASLDQHMQPAPPGGMAQQTGPMRFPEINRTKSQPNLREPQAAVFEMAAEMPPVPNGGFQAYNGQPMPPHPQAGPGSGHPAPIRPGLMPHSMVNMNDKPTPMRQYNGPPPAAIGAQGRPPPQPMQNGPPEPVPVTVEELERLRAIIKSDPNDQGAALTLAKKLVEAADVLVPRLPDPKARARSRERYVVDAHKILKKLVSAQNQDAMFFLADCQGRGTLGFEPDNKEAFTLYQSAAKLGHAAAAYRTAVCCEIGHDEGGGTRKDPLKAIQWYKRAATLGDTPAMYKVGMILLKGLLGQQRNPREAVGWLKRAAERADAENPHALHELGLLYESAQPNDTILRDEPYAFTLFEQAANLGYKFSQFRMGCAFEYGLMGCPVDPRASIMWYSRAATQEEHQSELALSGWYLTGSEGVLQQSDTEAYLWARKAAQAGLAKAEYAMGYFTEVGIGIPANMEDAKRWYWRAAAQDFPKARERLEDLKRSGKNGPRPRERISRSKIGKQQEGECSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUY9</accession>
    <name>A0ABR1VUY9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein RHO3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665937.1">
        <property type="nucleotide sequence ID" value="XM_066813975.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047035"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="209" mass="23179" checksum="B2A6276F49BA45D0" modified="2025-10-08" version="1">MPALCGGSKTVQRKLVLLGDGACGKTSLLNVFTRGYFPTVYEPTVFENYVHDIFVDSVHIELSLWDTAGQEEFDRLRSLSYDNTDVVVLCFSVDSKDSLENVESKWVGEIQENCPGVKLVLVALKCDLRENNEDDDEPAAGAADGAQREKRPMIDYNQGLDVARRIKAMRYLECSAMKNRGVNEAFTEAARVALSVKPSGEKDSKCVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV60</accession>
    <name>A0ABR1VV60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase PFA4</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Protein S-acyltransferase</fullName>
            <shortName evidence="11">PAT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Protein fatty acyltransferase 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PFA4</name>
        <name evidence="15" type="ORF">PG997_009796</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11 12">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endoplasmic reticulum membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11 12">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666073.1">
        <property type="nucleotide sequence ID" value="XM_066814111.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047171"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03199">
        <property type="entry name" value="DHHC_PAT_PFA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033682">
        <property type="entry name" value="PFA4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0564">Palmitate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="14">
        <location>
            <begin position="127"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="81"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="440"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="501"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="active site" description="S-palmitoyl cysteine intermediate" evidence="11">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8075133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="550" mass="61190" checksum="265C0B1630C9D74E" modified="2025-10-08" version="1">MAFLVGSTAPLSVQRLAVPAVCLLIAFLGYGSQVLFSRSPDLEPGPLTTTQTYTFNTLLLCLWWTYYRACTVDPGRYTFPPSIAKPNHSDDEGEGEGGKTGTHGKKAAAGGGNDGSAMGNKKGGRSQKRCKKCRLPKPPRSHHCRICGRCIPKMDHHCPWTSNCVSLQTFPHFLRFLVFTNVSLWTLLYFVFQRFHALWANRHLPAYLGPTLPQLIWVTMFALVGMGTSLALGILLGTTLQGWLFNTTMIEGWEIERHDALLERRRGAFGDGGGGGSNYDGDDGYWETRRDADDPALLRLDPVEFPYDIGIFANMAQAMGTANVLLWFFPFASGPRKGGDTTGWEYEENGLNDDEGMWPPPDPAKMRHSRAWNEKRRRELAAEREAYDRNSRGGANNNADDVQAFRRRQEMDMRRRWQQGGGVGGGISAQQEAGRILGELEEVDGGGYEFVDDDRYSYDNYEDQDQDQEDRPPHLGGGGIVVDEGKSGWVNADGEQLGDYGVDEDAEFDDDDVLVDPVDDEGEESHEDDDVPLAELIRRRKVLTKDGADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVC7</accession>
    <name>A0ABR1VVC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666087.1">
        <property type="nucleotide sequence ID" value="XM_066814125.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047185"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF3">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="29664" checksum="E55F8659BB99AF31" modified="2025-10-08" version="1">MGGSLSKPDPSRSSLEVIGAGYSRTGTSSMQLALEKLVDGPIYHGGTQIWLSGDDRRTKLWALACDAKYVQHDAALTRKLVREAVRGYAGLVDIPGIWFVPELVDLFPGVRVVLNTRAPDQWWPSFANVLGHLPPLFGLLTAPRPSVRWIPGILRGFERSVDELLVADGREPGKYGPFLLDLYQNDIIQSVPKEQLLVMEVKDGWPPLAQFLRKPVPDEDFPRVNEKAAFDRQAKAILIKLVLTWVGIVVTTGSSAYLGWRLWQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWB5</accession>
    <name>A0ABR1VWB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BNR/Asp-box repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666473.1">
        <property type="nucleotide sequence ID" value="XM_066814511.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047571"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792">
        <property type="entry name" value="BNR/ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792:SF3">
        <property type="entry name" value="BNR_ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="Sialidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="370" mass="40086" checksum="E81205635C440E47" modified="2025-10-08" version="1">MGGFTQKVMDKLNHIGNKNDPPPPPPPDSTRPQAAEPWHVGGHEFQLHPAGTGTYPRLARMSDGAILCAVTRFEGPTRVLTITRSTDNGASFEPWGEVSRGEGDCDNLFISEIPSTMENGGEGITVLGAFRNHDIGPNGPTHFRITVCRSMDGGRTWHFLSQAVEQSAAQSGGMGLWEPFIRVSPATATETFRVDSHDGGKTWSAPRCLRCHPPEERLRDGMQGIVTTRDAATGAEALVIVFETTRHGTFSVEYSVSYDDGASWGARGVVFCPPWGRNAGAPQISTFGHGGFACVYMTDEDAAEVAWPRHASIKVSFAQGLRDGRVEWSRPVNVHQGPSSWPGVLPMGPSEMLAVYEHSGKPIGRMLHWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWD4</accession>
    <name>A0ABR1VWD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010205</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666482.1">
        <property type="nucleotide sequence ID" value="XM_066814520.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047580"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF332">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="503"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="539"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="173"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="562" mass="60713" checksum="A0FDDA11E90134BE" modified="2025-10-08" version="1">MADAISPNDLRHEAEVVAEHLPESHGYVFDATSDAGNVGRSSTPDSNPPGEISSLKLPGGDIHRDVFKTAARVKMHKRAATFHHPGQAPTFDDDDLMSVGQQMGPGGFRRAYIQQRQQHLAARMPVTRNFVEFLDLYGSFAGEDLADSDDEAVSFEDDEEATPGVPALSKSATAGTTKTFFTLLKAFIGTGIMFLPKAFSNGGILFSSITMIVVAAISMVSFHLLLACKTKYPGGYGELGHAIAGNRMRGLILASITMSQLGFVCAGIVFVAENILSFLAAVSRSGAPLSTSSIIVIQILILIPFAWIRNISKLGPAALFADICIMIGLGYIYYYDVAKLATEGMAESVVLFNPDRYTLMIGSAIFTFEGIGLILPIQSSMAKPEKFEYLLGSIMLIITIIFTSVGALCYATFGDATGIEIINNYPQTDKFVNAVQFLYSLAVLVGNPVQLFPAIRILEGKFFGHHSGKKSLTTKWIKNLFRASMVLGCGLVSIAGASNLDRFVALIGSFACVPLVYIYPPYLHYRGIATTRTEKICDIALMTLGLVCMVYTTIVTLVNSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWJ3</accession>
    <name>A0ABR1VWJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA recognition motif-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666507.1">
        <property type="nucleotide sequence ID" value="XM_066814545.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047605"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24709" checksum="96F440BCCC59815A" modified="2025-10-08" version="1">MAVRPGEENVATLFGDIHYFYGPPTAKPPHHRFDKGSYVYLFENANDRRARIEVANQPGEDDQDAFDGFLDHAHLKYSYKQQCLVNITVGDGVPDQSQWHLPTYDPHNQNKYHYKLHSLDIYFWTQNDALQFVNGIRRVLPGHQVVVLDEPAPPPQQQQQRQQYPSPHYDPVNPLVHKLENAVISEPPRFGAGTGVPYRHRRQKGAPTGRPLSNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX22</accession>
    <name>A0ABR1VX22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">(4-O-methyl)-D-glucuronate--lignin esterase</fullName>
            <ecNumber evidence="7">3.1.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67452"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:171667"/>
            <dbReference type="ChEBI" id="CHEBI:171668"/>
            <dbReference type="EC" id="3.1.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:67453"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate esterase 15 (CE15) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.117" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666687.1">
        <property type="nucleotide sequence ID" value="XM_066814725.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047785"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054579">
        <property type="entry name" value="GCE-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22244">
        <property type="entry name" value="GCE_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="4-O-methyl-glucuronoyl methylesterase-like" evidence="8">
        <location>
            <begin position="78"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="376" mass="39295" checksum="24E847D676DC07F0" modified="2025-10-08" version="1">MARNLSDTCTVAGDTPAVNVAKLPDPFTFASGTKVATKADWTCRQQEISKIMQQYELGDLPPPPDKVEATLSGNTMSVKITVGSNTATLNSNIRKPSGSSGSGGPAIVTIGGSSLPIPGTVGTVSFGNDAFAQQNGGNSRGVGTFYNLFGKSHSAGALTAWAWGVGRLIDGLEQLGAAKTGIDPTKLGVTGCSRNGKGAFVVGALNERIALTLPQESGSGGAACWRVSDSQKQKGANIQTASQIVGENVWFSPRFNQHTSRTSTIPEDHHMLAGLVAPRGLFVMENDIDWLGPVSTTACMRAGRLIYTALGAPEAMGFDLTGGHGHCQFPAASRTNLDAYINKYLLGTGTPPNNLEKSPSNVNMADWVDWTPPTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX84</accession>
    <name>A0ABR1VX84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010120</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666397.1">
        <property type="nucleotide sequence ID" value="XM_066814435.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047495"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="6">
        <location>
            <begin position="196"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="512" mass="57332" checksum="260DEA1DA4A6F41C" modified="2025-10-08" version="1">MHLQQTFRAPEAAQYLGLGGFYFNGIHLGGISSNQGIPFFSKQGKEWIHAHTGSKPAPQPPCPPNAPTQVTGLWELPDRAVVNTYLSIFTTSIRRYVFPIIDEAAFPDVVEKAYNGHPDQADVVCAKACVLAFTCIQVHMEGQLDIQPSLTVRADQCAARVYRLMPTILASSCSESVQVCTMLCMYNMFTGNVAAAATYLSVAYRFVTMLGAHLNPVSMDPTSDTDNPHSSQRYLRRVFWHCYMYDKDISLRGGYISIINDDYCDLTLPPGYKEIDGFDSFKDGTDLIPGDMRLTIIKSNMIRRLYCAKAFRTPDVDLLKHIRELDDELDQWRISIPPRYRPSLVSSYRMELASDWNKAKQAHILVIHFEYYFLLSLIHSASGRCRIPASGGVDHRASVNSCQCLALQASRTTLANLPVVSQVLSRGDFWYFIQYPLSASLTIFCNILTSPLNAQAGEDLELLQRVPRLIRDMCAVPCVSPGDNMRIRQVEQFVEELLRLGRSAVQEAAAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W0A8</accession>
    <name>A0ABR1W0A8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010206</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666483.1">
        <property type="nucleotide sequence ID" value="XM_066814521.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047581"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF15">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047246759" description="Beta-lactamase-related domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="4">
        <location>
            <begin position="56"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="400"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="412"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="556" mass="62117" checksum="F4D97277EC65D635" modified="2025-10-08" version="1">MKRHVVPVFAIALHALLSPSVGIRLEDENYQYPIGGEYGGSDAYRTSLSFSTEKLESYIHEVMDRWKAPGMAVAIVHGNETWAKGFGFASLPSTPVTPHTLFYTGSTTKSFTAAALSLLIDNSSSSNSDTGTTKLTWTTPISQLLRDDFVLSDDWATAHITLEDAASHRTGSAPHDLAFVKSSRDQVRRLRYLPLAAEPRQRFQYNNHMFTTLGYLVETLTGTWLGTFFRDRLWAPMGMDETFLNRGDPRFNEAESRLVLAEGYYWRKRSNDGHGEYVKRPYVPADWDTGAGAVISNVLDYAKYLRAMMREQGPISAAGHRELRTPRTFLDARGAPLFTGPVMRRRQEKQGRKLVHDGRKRLYPHVPDPPLPPSVALYKHEGRYHNPGYGEMIVNLVCDGENSGGSSGPHMQKSESEPPETARKGDDDCHLEAHLADTSIFKFTFMLEHVSGDYWIGWAHVKGVTDPDEPLTAVRAQFRLDERGEVSEVGVDLSGLRGRRDRQQALGNLGSGHGDEPVQEKTGGFHLEDSWKMIRGITSSKKDLHGLVRLMTLVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7U1</accession>
    <name>A0ABR1W7U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CENP-B-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007378</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667035.1">
        <property type="nucleotide sequence ID" value="XM_066811693.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044753"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041188">
        <property type="entry name" value="HTH_ABP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18107">
        <property type="entry name" value="HTH_ABP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="85"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="233"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="336" mass="37605" checksum="6D2C820C825B1B6E" modified="2025-10-08" version="1">MSAMDVTNDPDESTVSVESPKERHSLTLDQRRALRRWAHSQTTRPSHKACIEWFYSQFGQNISQSTISHSLSPKYARLDNDSQFSGSRLRFGNWPDVEKLVLLWHGQVVSSGRNPSNEELAEKAKSIFSQLPRYKDENPPEFSPGWIHRFKKRYGLLIRRQRRHGSAPNPADDIPYLVDAVPRFMTINQETSPAAIRDAVMRVQPLNPPEVDAFPDEDPEVVLQNALRALQQEEADAEAEAAAVREERERQESGLPPIAGLSTPGHAPPPQPGPPRSGAGARFTPQAPDELTLTPISSGGPISQSDRPLRCPFCVNHRMLRTIKEAVEHMSTHVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W804</accession>
    <name>A0ABR1W804_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histone deacetylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667017.1">
        <property type="nucleotide sequence ID" value="XM_066811675.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044735"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09998">
        <property type="entry name" value="HDAC_Hos3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053244">
        <property type="entry name" value="HDAC_HD_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47558">
        <property type="entry name" value="HISTONE DEACETYLASE HOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47558:SF1">
        <property type="entry name" value="HISTONE DEACETYLASE HOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="2">
        <location>
            <begin position="281"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="662"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="746"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1074"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
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        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="755"/>
        </location>
    </feature>
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        <location>
            <begin position="757"/>
            <end position="767"/>
        </location>
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        <location>
            <begin position="798"/>
            <end position="807"/>
        </location>
    </feature>
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        <location>
            <begin position="822"/>
            <end position="839"/>
        </location>
    </feature>
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        <location>
            <begin position="864"/>
            <end position="880"/>
        </location>
    </feature>
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        <location>
            <begin position="917"/>
            <end position="927"/>
        </location>
    </feature>
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        <location>
            <begin position="947"/>
            <end position="958"/>
        </location>
    </feature>
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        <location>
            <begin position="984"/>
            <end position="994"/>
        </location>
    </feature>
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        <location>
            <begin position="995"/>
            <end position="1013"/>
        </location>
    </feature>
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        <location>
            <begin position="1033"/>
            <end position="1044"/>
        </location>
    </feature>
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        <location>
            <begin position="1045"/>
            <end position="1059"/>
        </location>
    </feature>
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        <location>
            <begin position="1123"/>
            <end position="1132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1153" mass="125055" checksum="8875DD712BC75541" modified="2025-10-08" version="1">MASTPNRSLAAQPDNAATNKPPRRSDVDATLAQSMQNVSLDSPGPHNAHTKPSPRQNGPLPHPIHPPLSTPDRANLGVSPNGGRNSSRSPVSRSVSTGARPQSRSGTPNLLRKSSNTSLRSTSGITPSRAPSRGASRRGSSASLVSPAPRSPMNFGPQPVMEEPPRPRITEGSIANNYFQSELDMLHNSVAAKKSDTLVVLHDSCYGHRFSRPKTTKGNLATIVERPERLQACALGVALAYVRLGERHCDGKVPITPDLDPATLATIPFRIRKTDRTISLTSPIVTNVHGSKWMEELGMLCDAAEAQLASGNSELKRPIMDRGLGVENPKPFHEGDLYLCKESLAAFEGALGAVCEAVDAVLMGQAKRAFVGVRPPGHHCSAHHPQGFCWLNNVHVGIMHGFMNHGMTHAAIIDIDLHHGDGSQAIAWDHNTRRIKQPKNAAAWKKSSIGYFSLHDINSYPCEAGDIDNIKNASLCIDNAHGQNVWNVHLQEWSSEVEFWRLYQSKYSVLLEKTRNYLRRETERLRAAGQEPKAAIFISAGFDASEWEGAGMQRHTVNVPTEFYARITRDVVKLAAEEGLSVDGRVISALEGGYSDRALCSGVLSHISGLAGTDVKNAKEESPSHCDVRIEMPGFPYDPKWWSQQELDQLDAAKTPHVVLPDPRIPRQGPIPTYCSPTQSSVLKAVDPDKVRRTASGHLTTQPAPRAPTPPPPEVHWPVAALELSKLLIPTDRPVSSVTWEEMKADTNRLKRDRQSLPAQNVESAENNGGVRKSLRERRQVRPSSPTEVKTRGHSRRSTMTNASSILQEKKQASARGIPAHAASTSSRPTSRRLSSASTFMTNSDDSLDAANAMPPPPYYPRPDTSQSIRPESSMSVRTNDTLDVRKTRPAASRSQSAVDAPKRAAKAPTTGTKPPGRPKSRASKKKTGFDSGGLPPATAQERPATSHVTSSTPSLSPSRAGPDSDDEVSRLTHGVKKITLVTKEMREAREAAKKAQAPNQATTPAAAKPAAKVRPSSINTEHPVAMMDRPKSSGPLSSTLPSTRKNQAQSLPATSPTLPMTPLIEVHQPTLVNPQALPHTGPLKWLPPNQAETPRLPKKGHNFTAKSSIPFADTPTKDKHVNNTNGQQAQTPVKVEKQEGEIWEIPETPDCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8W1</accession>
    <name>A0ABR1W8W1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667410.1">
        <property type="nucleotide sequence ID" value="XM_066812068.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045128"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="120" mass="12897" checksum="1A81CCED1947B359" modified="2025-10-08" version="1">MAERKESQVTAAQQPPINQSPSEPQAGGCPLGVPLGIPTTAAVSPPNLSRIASRLQCLAAHSLFVWATWRRFRLGGRGMPSWEAAAPQDVAIFRGCPSIVMPNLPMYSPFGARLPEQYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9E7</accession>
    <name>A0ABR1W9E7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667577.1">
        <property type="nucleotide sequence ID" value="XM_066812235.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045295"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="323" mass="36512" checksum="66459AFA9E040895" modified="2025-10-08" version="1">MAVPSLKLASGHKMPIVGFGLWKVPRESCADTVYDAIKCGYRHFDGAWDYTNSAEAGQGVQRAIKEGLVKREDLFITSKLWCNYKKRENALQMAKLENEAWGLGYLDLFLIHFPISLKFIPFEEMRWPCFWTDKEQTKVTPLDPVPVSETWGALEELVHNGNVKSIGVSNFSAQLIYDLLSYAKIPPSVLQIEHHPYLTQPDLVKLAQDNNIQVTGYSTFGPLSFLEMDHPKAKSAKPLFETDVVKSIAEKHGKSPGQVLLRWCTQRNVIVIPKSNNVDRLKQNLDCCSFDLTEDEINQISGLNIDLRFNNPATLSTPIRIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA58</accession>
    <name>A0ABR1WA58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667823.1">
        <property type="nucleotide sequence ID" value="XM_066812481.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045541"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142">
        <property type="entry name" value="METALLO-HYDROLASE/OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142:SF2">
        <property type="entry name" value="METALLO-HYDROLASE_OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="351" mass="38091" checksum="523DD54E5E9D0CB9" modified="2025-10-08" version="1">MSAQDENPTFNISDRAKLRSTLLQATDEPVLIHLNADTTWLVSLPYPPTASATKPLAGSGRSSGRSRFNILLDPWLQGPQSDVASWFSTQWHLVAPSVQTIDELNRLLAEVELGDAKKKAGEGEQPASLIDVVAISHEFTDHCHETTLKELPRETPVFATDKAAELIRSWKHFDSVITTPGFSSDDTADWRKVLSVSPLPDWVGIGRVITAGNALYYHSAIMIAFKTAGTDKTEENNVQPDSTTAAAAAVIYSPHGIKASDLASVKSAGIETRALLHGLHDVRIWMTKQLNLGALNGLEAVRASGAKYWIATHDEEKKGADAVQRETENMGDQAPEYQFVELGSGDALVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAQ5</accession>
    <name>A0ABR1WAQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008392</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668049.1">
        <property type="nucleotide sequence ID" value="XM_066812707.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045767"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044998966" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="19"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="21"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="170"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="416" mass="45012" checksum="A77C5E0E632F9577" modified="2025-10-08" version="1">MFFLSAFASSLLIAAVRGAELTVPTANGEVRGTINATSPHVRQFLGIPFAEPPVDKLRFQPPVKYAAKDRDIDAKAFAPSCMQPLTTPESDAKDVFHVYMPQLLPGSPAQSEDCLYLNVYAPLEPTAEKLPVFVWIAGGGFASNGANVPYQVPDPWVERTQGHVVVTINVEWVRDNIAAFGGDVDRIVLWGQSAGAWSVNYFGYAYPEDPIVKGLIAESGGSTVFASGDEEHRGFSAVAKNAGCGEGLDAAAEMACMQSVDAKTLQKVFANTTGFMFGPVVDNVTVFADPKDRSGGLVVCPWTAEEGVKEADMIAGSKVIVCPTIDEIRDRFEAGLTTYRYFYSGNFSNITPASWLGATHSSELPLIFGTHYQYNHNSTEFEWNVSHAMQGKYSVSKPSPMIIWRITTANLAGTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBC1</accession>
    <name>A0ABR1WBC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667235.1">
        <property type="nucleotide sequence ID" value="XM_066811893.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044953"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="155" mass="18599" checksum="A0C30403FDE2C854" modified="2025-10-08" version="1">MMNEIRQFFSYIAFFLLCGLFNLIIALFFREIFYLFKHLFVPPESQVAGNDGVFPEFYRAVYRRQSAKICYKFRRAFYRWCPPARWFFLYGKWETRRILRHFEFVGEGTRLCGASLLLCSYWAVCRHPFEAQMHSPDRGGVCGAYLNANRHRLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBQ0</accession>
    <name>A0ABR1WBQ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">C-type lectin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_007759</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; ergothioneine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667416.1">
        <property type="nucleotide sequence ID" value="XM_066812074.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045134"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="entry name" value="paralog of FGE (formylglycine-generating enzyme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051128">
        <property type="entry name" value="EgtD_Methyltrsf_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017805">
        <property type="entry name" value="SAM_MeTrfase_EasF-type_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03439">
        <property type="entry name" value="methyl_EasF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397:SF1">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="9">
        <location>
            <begin position="57"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="DinB-like" evidence="10">
        <location>
            <begin position="389"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase-modifying factor enzyme-like" evidence="8">
        <location>
            <begin position="574"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="723"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="806"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="806"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="833"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8079941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="921" mass="103516" checksum="1C1DE09BD6CB6321" modified="2025-10-08" version="1">MQSHAVDVFPDSQAFASDHKAGKSGGLYKEVDIIDIRQAAVEINLKEEIHKLFRPEEGPRKLPTLLVYDEKGLQLFEQITYLEEYYLTNYEIQVLRRSAAAVAKSIPSGSMVVELGSGNLRKVSLLLQALEDAGRDVDYYALDLSREELDRTLRQVPTFRHVRTHGLLGTYDDGREWLKKPDVAKRRKCIMSLGSSIGNFHRHEAAEFLRGFTEVLEPADTIVIGLDSCTNPSKVYHAYNDREGITHQFILNGLRHANEVLGSEEFKLEDWEVIGEYVYDNEGGRHQAFYSPVRDTTVLGETIKAHERIQVEQSLKYSKDGMQNLWRAAGVVESDRWMVEGDEYGLHLLTKPTTMEFGRKPSQYAQATLPSLDDWKNLWSSWDTVTQRMLPNEELLDKPIKLRNACIFYLGHIPAFLDIQLGKVTKLAPTEPAFYHSIFERGIDPDVDNPDHCHAHSEIPDEWPAVEAILSYQERVRAKLIKLYGDGQDSIPRDVGRAIWVGFEHEIMHMETLLYMMLQSDKTRPPSHTPVPDFKALAEKAYNERKDNVWFDIPEQCIVIGMNDPQEKLDFQGHFGWDNEKPAREAKVHAFQAKGRPITNEEYAQYMYDTKATKLPASWAGNKTNGNADGHTNGHVENGYAVPTSFLEGKSVRTVYGLVPLKYALDWPIFASYDELAGCAAWMGGRIPTLEEARSVYTHVDYMRQEQAERTLGKTVPAVNGHLVNNGVEETPPSKDSTLVSSKSSEGDGLFVDLTDANVGFNHWHPVAVTAHGDQLAGQGQMGGVWEWTSSPCRSMKASSPWPCTLDTQPTSSMASTTSSLVGRGPHTPELPAGSHSSTGTSATTYMLGAELDWSETCRTKWCLHQEGMNRKQWWQPVFNPGHHNRRTAQAALNPALPGRRGHHFAPVTAHICMVSSGFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WD38</accession>
    <name>A0ABR1WD38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667549.1">
        <property type="nucleotide sequence ID" value="XM_066812207.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045267"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="128" mass="13716" checksum="9A54DC14BA8B0DB7" modified="2025-10-08" version="1">MPALDGELQQAVEGLVVASRHDAVQLAGAARVPRRAYQQGPVRGLAVAAGAVYIDAPRQLVQRPAAVYLDCVEQFQRQGRVQPPRTPSQAREVAGVRHEVLPRVPQDVEHAAAGGLRLLWMAEEGLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE25</accession>
    <name>A0ABR1WE25_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667833.1">
        <property type="nucleotide sequence ID" value="XM_066812491.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045551"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="363" mass="40378" checksum="A13E8E207921C00B" modified="2025-10-08" version="1">MLSKRLEELSRDPSNPDSIVELAVTALGPQGSFYICWKTRSGQYQQDSHGLPPKLKEWLFPPDNSQRDFGSLQVILGPRDGEFLASDKNGKVDQKPTEPSPRPFSLNRASTFAPRDSSSTSRSRRISFISDVPEESDKTSRRRSATLSSLGWATNSNRRTLSLPKVPLDPTETEEQRKSRRTSLLPLTLQAVPSAPAPSVERNVSDVRVQATLSPTPFAPSQQESIPEEPQRAPRVPVSVPVRRPRPVSCYADACVQTEVVEEEEEPDTPLASYQTKRRHLRERSSVSSASSVFSAGSDFSSRRTSVASDFKVDNGNCWAEEPPVLANPICMGRMQDYFRAGSYQLGDAFTTPSNTYWGSWRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM22</accession>
    <name>A0ABR1WM22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SPIN90/Ldb17 leucine-rich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669046.1">
        <property type="nucleotide sequence ID" value="XM_066810123.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043183"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030125">
        <property type="entry name" value="SPIN90/Ldb17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018556">
        <property type="entry name" value="SPIN90/Ldb17_LRD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357:SF1">
        <property type="entry name" value="NCK-INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357">
        <property type="entry name" value="SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09431">
        <property type="entry name" value="SPIN90_LRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPIN90/Ldb17 leucine-rich" evidence="2">
        <location>
            <begin position="188"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="508"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="518" mass="58404" checksum="4694C0E693BFDEE3" modified="2025-10-08" version="1">MEESDMTYTIETEEQLWDELNEVLTRTCAAHDFESLDDSLRRWLDLATKCRQDFSQSEDDVFTCSDRLLNSPLFQTDPHYVRTQIIYSMLQEDEPASLYAIASFLLLDGRADETTYREMVNEGCFHRLLELMNGHRDDDPRLYRLLLELMYEMPRFERLRPEDLMHVDDGFVSYLFEMTEGLSDDAHDPYNYAIIKVLLILNEQYMVASTAAAADPTSPNALLTNRVVKCLCLYGPQFRTFGENLILLLNRETETSLQLLILKLLYLLFTTKATYEYFYTNDLRVLLDVIIRNLLDLPYELMSLRHTYLRVLYPLLAHTQLNQPPYYKEDHIVKVLRIMAGSGNAHFAPADETTLRLVNRVRKVSWLPHDGAGEVANRLLGISLESQDAGSKISVVDVAAVTEKPGVQTPSRKAELSTAEQAGDADAPPTSPEDVVAPSNSGEATSSKEPPPPRKPKKPLPEVPKSRHGKPFAPVVHINTNGNAPAVAAKKLPPQAPPPRRRGKLKAAESAAPAAHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMX0</accession>
    <name>A0ABR1WMX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669388.1">
        <property type="nucleotide sequence ID" value="XM_066810465.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043525"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19077">
        <property type="entry name" value="AKR_AKR8A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF78">
        <property type="entry name" value="PYRIDOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="327" mass="35715" checksum="8DFD87078D9CFD1F" modified="2025-10-08" version="1">MPQLMGKEIGPIGFGLMGLTWRANPCSEEQAFETMRAALENGMNFWNGGEFYGTPDHNSLTLLDRYFAKYPEDAEKVVLSIKGGMGPSGIDGSPEGVRRTLDNCIKLLNGRKKIDMFEYGRRDPNTPLEVTFGVIDKEYVQTGKIGGISLSEVKASTVHEAAKITKIVACEVELSLFATDVLDNGVAAACAEHGIPLVAYSPIGRGILTGQIKSLDDIPQDSMLRHYPRFQPDTFPINIQLAHQVEEMAQKKGCTSAQLAINWTRAVSKRPGMPEIVPIPGATTADRVNENAKVVELSEQDMKELDETLSKFTPAGARYPPSIPMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNP9</accession>
    <name>A0ABR1WNP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006363</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669601.1">
        <property type="nucleotide sequence ID" value="XM_066810678.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043738"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19143">
        <property type="entry name" value="AKR_AKR6C1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="28"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="350" mass="39469" checksum="F5D3D671D1D9AF10" modified="2025-10-08" version="1">MPAVKSMFDPKDMQFRHLGPTGLKVSVLSLGGWLTYGGTQKGEIVKKCLQTAWDHGINTFDTAETYANGESEVEMGTALKELGWPRDEYVLTTKVFFGTGRKEPNTRGLSRKHVVEGLKSSLERLQQPYVDIVFAHRPDYATPMREIVEGFTQVIRNLNLAYYWGTSEWSATQIMEATQIAEKYNLIAPVVEQPQYNAFHRQRFEVEYKPLFQQFQYGTTIWSPLASGLLTGKYNDGIPEDSRFATNKSFFENTIKELQSPEGKAKIEKVRKLTTIAEKLGGNASQLALAWCIKNPNVSTVILGATKVEQIEDNCKSLQLSEKLTPELMEEIEKILDNKPAAPATFGRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNS9</accession>
    <name>A0ABR1WNS9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006344</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669582.1">
        <property type="nucleotide sequence ID" value="XM_066810659.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043719"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="4">
        <location>
            <begin position="5"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="337" mass="35994" checksum="10F91E807CCA09C6" modified="2025-10-08" version="1">MPAKRTLFRARLGVVLATGDPSTPSSTPAPPPSSSSTGGSACSGSGVALARQVGGAVISYICMEKTTKPPSPPSALPLARTHMSGIAELGRKAGGEAFLILDARQWALATKKPKPKAKERLLQKMKLGKKKADNSSNNKTNKLPRDKRAARKPQKPRHQKAATLHRLAKKIGVNADGLGQAVSEYNESIRAGREDEFGKKPEHRALALKKAPYYAVDISLPRGRSPTPRRRTRIVPFIRIDEESGLVHDEEGRHVRGLYAAGQYTIGGSVSGGGLEGAVYPLDEKVKNDGLDDIAANVCSARRAGEACGGVQEADDTLDRGGEHSRDVERGRCVCNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP18</accession>
    <name>A0ABR1WP18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669780.1">
        <property type="nucleotide sequence ID" value="XM_066810857.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043917"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="100" mass="10918" checksum="421B53F3EF8B0F81" modified="2025-10-08" version="1">MPKVCLHESGLNQIAFADMPLSAHRMLQRPGEYGFRQKVTPKLKAASNGDDDTQREEPMAVGDGPKRIDSMAKERVGKAANLNLRNAARGTAPLRLTVCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP37</accession>
    <name>A0ABR1WP37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669816.1">
        <property type="nucleotide sequence ID" value="XM_066810893.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043953"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="94" mass="10213" checksum="456B9661C4A0B1BB" modified="2025-10-08" version="1">MKRTPKPCHVLFAGDVDGILATARLGERNSPYQEMGMSTHMVERINHSVFKVIDRCRETGIINRSSPGSWVAVTGANATVCVNTITGLGRDKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPJ7</accession>
    <name>A0ABR1WPJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669958.1">
        <property type="nucleotide sequence ID" value="XM_066811035.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044095"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="173" mass="20008" checksum="EF6BB3BC7EAB8C2A" modified="2025-10-08" version="1">MLHRQVQRTKKKKPGHSSARPSVAADAETSSTTTTHTGIEERFGLLLIGEPVTKPGSGQKHQPPRPQRLRRRLMGGVRRAEGIPRGSYRGRRWQRQQERTTRRRYQHRRQQRGIVADVGRVKRPGPDHPSPPTHKRTESEPQCYGQTRFERRFMGVKLREGEYGEAARAKRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQG8</accession>
    <name>A0ABR1WQG8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006993</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670231.1">
        <property type="nucleotide sequence ID" value="XM_066811308.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044368"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF49">
        <property type="entry name" value="LYSINE BIOSYNTHESIS REGULATORY PROTEIN LYS14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046026989" evidence="3">
        <location>
            <begin position="20"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="35455" checksum="84DF2305B76B9212" modified="2025-10-08" version="1">MNETILATCLIWCLTDVFTYRQGASSSWRIHLQGIKAILDSNQTHRYFATSSGAAQSAMRHLYLLYLSLQTLPHVPAVAVTELSAKYDDVSLETPDELDEPTLGPKIDGFLGYSEELLHIIQNVNRLARLDVETAGSAQHEADILLGKLNAMINRDSVAPPGVTIYPVLSPESNREFELCHRTFQQATLIHVHRRLYRMPSNSRPIQAAVAAIGRMVTNMAQGQPCHTWVAMAMPLFTIGCEAFTDDQQSFVLDKIHKLYLCIGSYHVGIIRQALEDIWHIRRESGDLDGHMCAAKLLGKSIAERDLPHVLLLISSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WR60</accession>
    <name>A0ABR1WR60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Potassium channel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_006236</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669474.1">
        <property type="nucleotide sequence ID" value="XM_066810551.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043611"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF301">
        <property type="entry name" value="POTASSIUM CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01333">
        <property type="entry name" value="2POREKCHANEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="196"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="360"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="481"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="649"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="496"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="655"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="690"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8084965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="792" mass="88606" checksum="5E95704B6096699C" modified="2025-10-08" version="1">MNEAAELNDNIDSRAQAVDGTSHKGKDGITSPTAVLANSKSSRWWFASSAFPMIAGTLGPVASAFSICALVQTPWLTVINAIQLAIAIISNMFLLLNMAKRVRFSVAQPITIVGWYISAILLVALTSTASGSLVVEPEIEYVWSQAFYYGIFAAILYFIVASLMVVTVWGAQSGHYRKDFELSVSQRTLMLQTILFLVYLLVGALVFSKIEDGWDYLDAVYWADITLFTVGYGDFSPLSTLGRALLIPYALVGVISLGLVIGSIRSLMLDRGKRRLDARMLEKERRQLLRRMRRRGKDGVLEPIGYFGPGAAKTGPEDAEKSMRTEFERRQKEFELMRKIQNKASNRRRWTALAVSLSTWLVLWLVGAKVFQECERPYQGWSYFDAFYFCFTGLTTIGYGDLTPVSNSGKAFFVFWSLLALPTMTVLISNAGDTVVKWVKDGTLKLGNITILPGEHGFRMEIESLLKRLSLGGVFRNESIQERPPGFLGAAQPSNSDEENDEDEDEDEDQDEDEIESDDNAELGAREPTGSLPPKKAQEQESPSTLAFSEPAHGGNQIIAKATKSKAQKPRPQRNNTGNEDGLALASRVESIAREDFPSELPKTRSEYHLVLIDEIARVTKHLQHSPPRKYTFQEWAWYLRLMGEDERSAETHQRASRKPRKRKNNNEKKDINGQDDNSQHLQTVAGESPQASQGGLWPPNSSSSEQPLAESGAADADDGNKWSWVGHRSPLMDTREEAEWILDRLEQRLRAELLAVVEEKRGQIGVQEANVYERRHEYHPKKRNSVVIGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRJ0</accession>
    <name>A0ABR1WRJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670316.1">
        <property type="nucleotide sequence ID" value="XM_066811393.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044453"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046387520" description="GH16 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="15"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="257" mass="27999" checksum="B6851795027EB8C2" modified="2025-10-08" version="1">MAYRFSLLTLLAAASTTVHAAVPTVNGFTLAWSDDFEGAAGSLPQSRELDLHHGHVIQSYTKDPANVQLDGNGNVKITAIKNGEAWTSARIETQRKDFMAPVGGKMRIQASLSTPKVAQPLGYWPAFWTLGAAFRGVYTNWPIVGEFDILENVNGEDKNEGIGGSKAGCPNGPCPANFHTYALEVDRTAGEGQEKMTWFVDDVQYHQILPGKVEASAWKEAVTKPHFLLMNLAIGGAFPQQGREDDADGGYHLRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRJ1</accession>
    <name>A0ABR1WRJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_006039</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669277.1">
        <property type="nucleotide sequence ID" value="XM_066810354.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043414"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF14">
        <property type="entry name" value="PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="9">
        <location>
            <begin position="116"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8084768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="305" mass="33335" checksum="A078472D57F61B01" modified="2025-10-08" version="1">MFSKSTMDFNTPEILRRGLAQRHALASINTSNERFSRIFISGFIGINTLVYGGWLYTKFNPSYQPVRGRGGPGGRRQGSSSSSPWASRALQRLTGWLTTEFMQDNFLLGTRNLRAGRWWTLLTYAVSHRSLSHLASDMATFHVFADVAVRLYDPLSVAAVLCLGSAAAGALAQLSDWRHRRQDGVVQRRGAMQILVLHHAQGASAITKGLAMAVTVLRPCILVRSPLLPSVSVPLWVCSLGWFLYDGYELSGVMEDGLQAGHPGHLGGMAFGAAYAGLRLLVPAHRDASFMNAVGRRGDLMQGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS17</accession>
    <name>A0ABR1WS17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006685</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669923.1">
        <property type="nucleotide sequence ID" value="XM_066811000.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044060"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF134">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="568" mass="62222" checksum="C23AC8A07874A5AB" modified="2025-10-08" version="1">MATYDFIVVGSGPAGSALASSLSRTGAKPSVLLLEAGGKNSDPNLRVDGKRWLTFTNEEMNWGFKTAPQEHCDGRTIDYSGGRGLGGSSAINFGVFTIGARDDYEEWARVAGNDAAFGWNAMQKRFKQLENFSEKRPAHVAEKFAKPDMGNHGTDGSLKVGFAAEWEDDVVPMLEVFEKGGFPINPDHNSGDPMGMSALISSAHKGRRSTAQDLYADKPENLTIVTCEKVRNLILEGRKVIGVETKDKKYHASKEVIISAGALNSPAILMHSGIGPKIQLEKHNIPVVLDVPAVGQGLRDHNFCPLVYSRSETSTARKAFYGDQKTMDAALEQWKQDGTGPWSKFACQAGIGFFKLPALPAHPSFRALPASEQALLQKPTVPHYEVFTHFPMHWFLPAFPPEKLSYSCLLVFLYNAQARGEVTLQSADPDVPLRFDPRVLSEEFDRTAAVMALRDILDRVVKSEEYQKDTVEAMAVPAGDSDEELLAYWKYENHFILVAHDGHPEDGPRRRCPDAVVDPDFRVVGIEGLRVADMSVAPVLISGHIQAAAYATGLTCAEKVIQQHGLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WSA7</accession>
    <name>A0ABR1WSA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidoligase enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670328.1">
        <property type="nucleotide sequence ID" value="XM_066811405.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044465"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022025">
        <property type="entry name" value="Amidoligase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847:SF1">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12224">
        <property type="entry name" value="Amidoligase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="42885" checksum="164D52394D81F826" modified="2025-10-08" version="1">MTHGKEVEFLVRYVYQLDPEETGADPKEDLKQLKKANPGVVAIPWGEEAGGIVPVDCVRALKRNGVDINHFETDPEEKRARPVTTHHNAQYCLLAEFHRWNIEDDLTVEGTAEDRKRDKPAPGQPHFGWYGLELISPANPNTAASHQEMCFVLGVLRQKYGDRMRVNDSCGLHVHVGMGPYAIPVDRLKRIAAFLYAADPLISVLHPPNLQDNEFCCSIRRHANVTWGMTAAAAAEEIAGSTGGGSGMPIDGVWDAESRTGRQPVPLRDAVRELLACETGHGIYRLLQYLDRGCNYNFNNYRVIPEPKGFVTIEFRQHEGTLDPARIEAWARLCVGLTEWAAFDMTEEQLGEVAVATETVERQQKGVDALRQSLLRQLLGLGGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY49</accession>
    <name>A0ABR1WY49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">25S rRNA (Uridine(2843)-N(3))-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670959.1">
        <property type="nucleotide sequence ID" value="XM_066807341.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040401"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021463">
        <property type="entry name" value="Methyltransf_34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11312">
        <property type="entry name" value="Methyltransf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="47694" checksum="469919C8EC9BBE67" modified="2025-10-08" version="1">MPKHASAYHGTRNLFSMKSKPKKPSNKESKREDDELSASEAPAKASKLSPAELKQQQALLNIFSDTFADVLGLDNFTSVLQEVKSALYNRDFEKAFGNEQYLEVYAARWSPTRALCYAKVLEGIREQLEDLVVDGDRLRRLRAKGDDVDASAAKEANRRPLRMLSIGGGAAEIVAFASLLRHDGGDNQDASESSSDISEKPLQGDIRLVDTGPWGSVVSKLQESLTTPPRLSIHASPAAHKANRALVAPAERLSNNFAQQDALDMTAEQLAEAVLGKEEKPGPVLVTLLFTLNELYTGGGIARTTAFLRKLTACVPEGSLLLVVDSPGSYSEAAVGKGDDAQKKKYPMQWLMDHTLLTVDKKQPQQQAISDSTPTRRCRWEKLESHDSIWFRMAPELRYPFQLENMRYQMHLYKAVAITTTSPEENDTTATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY66</accession>
    <name>A0ABR1WY66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670997.1">
        <property type="nucleotide sequence ID" value="XM_066807379.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040439"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058268">
        <property type="entry name" value="DUF7962"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25907">
        <property type="entry name" value="DUF7962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="10"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7962" evidence="2">
        <location>
            <begin position="123"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="38002" checksum="D8AFD5656474F683" modified="2025-10-08" version="1">MATEDLPIVLYHYVHSPYARRVVWYLNLRKIPYTECLQPPILPRPDVAQLGVAYRRIPLLAIGRDVYLDTRLILQKLEALFPASEAHPSLAAASDNAEGRALHSGLLSAWTNDAGGLFWNGVFLMPADLPGTNDPKFLADRAEMMGLPRDAPSPISREARAARRPEALCEVAEAMHLLESTLLAGGGNGRNWLLGTERPTLVDIEAVFVFVWLAAMGALPKDTMGPAAFPRLYGWMGRFIKMAEAAEKENGAAKSASGDEAAKAIFGSAFAEAEGSVDGSNPIVVAEGLKKGDLVKVWPTDSGSGHKESGKLVSMSLKEIVVEVQGKEGSVRVHAPRHGFKVKKDVEASSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY96</accession>
    <name>A0ABR1WY96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pci domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003094</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671027.1">
        <property type="nucleotide sequence ID" value="XM_066807409.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040469"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056124">
        <property type="entry name" value="DUF7707"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118:SF2">
        <property type="entry name" value="CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24808">
        <property type="entry name" value="DUF7707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045909018" evidence="2">
        <location>
            <begin position="20"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7707" evidence="3">
        <location>
            <begin position="28"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="214" mass="22231" checksum="6AD46C09C582DBA5" modified="2025-10-08" version="1" fragment="single">MFSHNIAVVALSALTVVSATSSNWTSLMDINKVPVGTRNGWCQAQLNACDQICSPPSQSTCDFVCYLLLGPRPVEYLTDYFPTQNTLDYQCACADGSDPKLGQYTNTIDYFTCQEAYSECNLANVGSKTGQDNCTATIQKNCGTKDPSKKESSGSGSAKSSSSAAPSPTSGGSSSATQSPQSSEKPKSAGLSLSAVSYMGNGAAALAVAAFAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYK8</accession>
    <name>A0ABR1WYK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671144.1">
        <property type="nucleotide sequence ID" value="XM_066807526.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040586"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="444" mass="47628" checksum="E18FC43B688E166A" modified="2025-10-08" version="1">MSQLLGTLHQEQPREDASATSAAGESHTDVLFGVVDGIADPCRLHSKPNQGLSIIYGGTASLLPSLWEQGKIAGKGHPDRASAVQFTAHEVENIDDQEVPTPVTLPLANTLFQNGRRSTLFASRWSLASSASASASGHHPMELTRLEEKSHQEVACLRGLEGLPVRIPLMPIAPPRKIVAGLGNIVRQVEVDGVVSPAAAAWLAGDGTGQAPSPMGVWAWVMPAWTVDKMRYDTAFKTYLGNQDAEEWRLDVEAREIYGELLVAECRMHKILSGGGGWGAKQGLLSLDPETTYAAPEQDDIDVFIKAFEERNNSASQSSSDGIVTPGSYIMFCAEPDRSGDVPSSSVDPASDLVSSRLTLTVAPKDEDLLPSVEGATDAKEGKAEVNVVPGHFGAASSTGLYLKSPCPHTSWTTKIDAPYSALSWDWTPRILWTIEPSTYVCTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZL3</accession>
    <name>A0ABR1WZL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671453.1">
        <property type="nucleotide sequence ID" value="XM_066807835.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040895"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF2">
        <property type="entry name" value="SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="29"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="296"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="297"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="339"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="400"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="450" mass="49997" checksum="DBC832D6165FC8CD" modified="2025-10-08" version="1">MAAAKEREGDLFIQEVWGLTGTAIVFVILRYYARLKAVGFKGLTADDYLMFPATVVMSIESMAGYMVVAWWKGFANNAISDPDRATLAQQARLDPNGAAAEEIRLRIGGSKNHVVGLLMYTTLMWLLKGCWAFYYNRLTDGVRNRRLLTKGSIIVLPATYIGCLLVAFLKCVPFDHHWQVFPNPGVNCMPAISPLQTIFVMVMNTVTDFYLMAIPIPMIWKSKLPLKKKLMIILMFSGAILEMVFGILRAVAIIKDGDTNPAESGYWSIRESFVSFVLTNLPMVYPLIREYSNQLRGKTGSTTGKSTGNSYQLSSYPRKSKNNRSRDPHTVPNESITFDSKENICVDTLEHPRPRGSSGKGGEDDGSPDMSKQEELEAGDAAGRAYRTRLRDPEAGQGGYQTSAKRSSSQRRPADPRQREPRSTQVTITTEYTVSDGGKIKDQSGSAYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X073</accession>
    <name>A0ABR1X073_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Superoxide dismutase [Cu-Zn]</fullName>
            <ecNumber evidence="5">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003731</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="5">Binds 1 copper ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671664.1">
        <property type="nucleotide sequence ID" value="XM_066808046.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041106"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00305">
        <property type="entry name" value="Cu-Zn_Superoxide_Dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00068">
        <property type="entry name" value="CUZNDISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00087">
        <property type="entry name" value="SOD_CU_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00332">
        <property type="entry name" value="SOD_CU_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Superoxide dismutase copper/zinc binding" evidence="7">
        <location>
            <begin position="18"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="164" mass="16975" checksum="9E329EDA042533FE" modified="2025-10-08" version="1">MASDGVWAVAKVRGDAKVAGTVWFRQKSEDAETEISWDITGQDADSQRGMHIHAFGDNTNGCTSAGPHFNPHGQTHGAPSDEKRHVGDLGNITVDGNGNAKGTVKDKLIKLIGPHSVIGRTVVVHGGTDDLGKGGNEESLKTGNAGPRPACGVIGIASAQEGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0J2</accession>
    <name>A0ABR1X0J2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003838</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671771.1">
        <property type="nucleotide sequence ID" value="XM_066808153.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041213"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047132550" description="WSC domain-containing protein" evidence="7">
        <location>
            <begin position="30"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="8">
        <location>
            <begin position="40"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="189" mass="20164" checksum="FF15CECFE48FDFB1" modified="2025-10-08" version="1">MAAIMKNSRMAVSFVAILMLALYSSTATATDLANFNGSSKFVYGGCYLETQGLNGSTSRTLKDESDIKPDQMTVAMCLDFCAKFRFAGLEWSRECWCGNEINLRATKKNDTDCDMACPGDKNIACGGNLRLSVYNSTVPSPATSTFNTPSLTMSPTATNTPGKNAAAMTATVIWAVLFARGMALSLGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X244</accession>
    <name>A0ABR1X244_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">carbamoyl-phosphate synthase (ammonia)</fullName>
            <ecNumber evidence="7">6.3.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ammonium-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Arginine-specific carbamoyl phosphate synthetase, ammonia chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutamine-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_004439</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.16" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672372.1">
        <property type="nucleotide sequence ID" value="XM_066808754.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041814"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01423">
        <property type="entry name" value="MGS_CPS_I_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="entry name" value="Carbamoyl-phosphate synthetase, large subunit oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CPSase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CPSase_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058047">
        <property type="entry name" value="CPSase_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003671">
        <property type="entry name" value="PRK05294.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF53">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25596">
        <property type="entry name" value="CPSase_L_D1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="Carbamoyl phosphate synthetase, large subunit connection domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="14">
        <location>
            <begin position="175"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="14">
        <location>
            <begin position="693"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="15">
        <location>
            <begin position="958"/>
            <end position="1107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8089478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1107" mass="122006" checksum="D29536AC5A07F0CF" modified="2025-10-08" version="1">MAFSTKLAGRGPALLRHGRRLPTALPRRQLTTVTAPTYSKLLAQSRTSELVQKRTLSCSAVRCAATIQEAPSSKAYIESGIIKPKDIVDVKKVLVIGSGGLAIGQAGEFDYSGSQALKALKEAGVASVLINPNIATIQTAHVLSDEVYYLPVTPEYVTYMQRMGIFERYGVKVLGTTLNEIDIPIAHSIAVNTIEEALDAAQKVGYPIIVRAAYALGGLGSGFANNEEELRNMAARSLTLSPQILVEKSLKGWKEVEYEVVRDANNNCITVCNMENFDPLGTHTGDSIVVAPSQTLSDEEYHMLRSAAIKIVRHLGVVGECNVQYALQPDGLDYRVIEVNARLSRSSALASKATGYPLAYTAAKIGLGHSLPELPNAVTKTTTANFEPSLDYIVTKIPRWDLAKFQHVKRDIGSAMKSVGEVMAIGRTFEESFQKAIRQVDPGFVGFRVPIGQAMLHEGYTVERVHELSKIDKWFLYKLQNLVDCTREMEKAGSLENLKKDLVMKAKKLGFSDKQIATAVKSNEDAVRAHRLGMGIRPWVKRIDTLAAEFPANTNYLYTTYNASSHDIDFKDQGTIVLGSGVYRIGSSVEFDWCSVMAIQALRDMGKKTVVVNYNPETFSTDTEVADRLYFEELSYERVMDIYELETASGVVVSVGGQLPQNIALRLQETGKANVLGTDPKDIDKAEDRQKFSEILDSIGVDQPDWKELTSVAEAEKFADQVGYPVLVRPSYVLSGAAMTVIRSQEDLKEKLEAASNVSPDHPVVITKFIEGAQEIDVDGVASKGELLVHAISEHVEQAGVHSGDATLVLPPTNQDDRTMQRLKDIAHKVAKAWNITGPFNMQIIKADNPEGGEPLLKVIECNLRASRSFPFVSKVLGTNFIDVAAKALVGKDVPEPVDLMAVKRDYLATKVPQFSWTRLAGADPFLGVEMASTGEMACFGKDLVEAYWTSMQSSMNFRVPEPGEGILFGGEVSRPWLTKIADYLSPLGYKFYAAGDDVKEFLEKTTKNQDKVEVIEFPVKDKRALREVFKKYDIHGVFNLALERAKTTTDVDYVMRRNAVDFGVPLFMEPQTAMLFAQCMSEKLPRNEGVPSEVRRWSDFIGGKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2F8</accession>
    <name>A0ABR1X2F8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Phosphoacetylglucosamine mutase</fullName>
            <shortName evidence="11">PAGM</shortName>
            <ecNumber evidence="4 11">5.4.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Acetylglucosamine phosphomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">N-acetylglucosamine-phosphate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_004571</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23804"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="5.4.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.3" evidence="4 11"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672504.1">
        <property type="nucleotide sequence ID" value="XM_066808886.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041946"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03086">
        <property type="entry name" value="PGM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049023">
        <property type="entry name" value="AMG1_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049022">
        <property type="entry name" value="AMG1_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016657">
        <property type="entry name" value="PAGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955:SF1">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21405">
        <property type="entry name" value="AMG1_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21404">
        <property type="entry name" value="AMG1_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016408">
        <property type="entry name" value="PAGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="60"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="103"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="15">
        <location>
            <begin position="207"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="14">
        <location>
            <begin position="307"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase C-terminal" evidence="12">
        <location>
            <begin position="462"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8089610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="548" mass="59709" checksum="F5B6F055A2375579" modified="2025-10-08" version="1">MERDSIIAASQKHDIAALPDGKLYTYGTAGFRMAADLLDGITFRVGLLSALRSRKLSGQAIGVMITASHNPAKDNGVKIVDPMGDMLEQEWEVYATQLVNCATHEAVADTFFQLAEQLKVDLKSGAKVIAGRDTRPSGITLLQALSDACSATNTSFVDYKVLTTPQLHYLTRCVNTEGTPSSYGEVSEAGYYKKINSAWERAMKNKKASGALTVDCANGVGGPKLKELLKLMDPSKTGLECKVVNDDVLKPEVLNLDCGADFVKTRQRAPPNPKPQPGGRWCSLDGDADRLIYYWIDPETTQFFMFDGDRIATLAASFIADLFRTAGLDGELRIGVVQTAYANGASTKYVEQHLQLPVVCTPTGVKHLHHAACAFDIGVYFEANGHGTVLFSTDAVQTFEKKQPQSPAQKEALDTLRALADLINQTVGDAISDMLMVEVILAHKGWGLRDWAMTYQDLPNRLVRVEVGNKDLFQTTDAERKLSQPAGCQDEIDQCVKKYTNARSFARASGTENYPSQACRVYAEAATRSEADDLANKVAHIVKTYGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2J9</accession>
    <name>A0ABR1X2J9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lumazine-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672503.1">
        <property type="nucleotide sequence ID" value="XM_066808885.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041945"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006767">
        <property type="entry name" value="PRK09289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098:SF0">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="108"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="108"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="251" mass="26149" checksum="2EBEC8630E6CEF86" modified="2025-10-08" version="1">MFTGLVEEIGGTSLRAQPQDATGGTSLTISLPATSTLLSDAQLGDSIAVNGVCLTATSITAAADPKPSFTVGIAPETLRLTNLGRLGQGSRVNLERAVRADTRMGGHFVQGHVDTTAAIESVTPDGNALTFRFRPEAQDMLRYIVFKGYVTIDGTSLTVTKVDDAAGWFEVMLIAYTQEKVVVAGKKPGDTVNIEVDVLAKYAEKSMQGYMSAKVGGAGVGGEPGSEPALKSIVEKMVQNVVAQAMGAHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2N8</accession>
    <name>A0ABR1X2N8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004638</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672571.1">
        <property type="nucleotide sequence ID" value="XM_066808953.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042013"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF5">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="567"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="133"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="597" mass="65724" checksum="3AD61A169AEDF585" modified="2025-10-08" version="1">MVRLLGWRFLQYRPESVHDYAGVLVPLEEAHLHSHSARSGRTEFEERRNGEEEDGEGADPLMQADDDEADKDRESGEGMGMLQMSAAEYTIEGLRREMRQGERGRVWTEYELKSKLINKAIQDIGMGRYNWQLFILCGFGWFADNLWFQGVSLTLPSLTGEFGVPEKTVRYTTSALYAGLCVGSFCWGLGSDILGRRIAFNATLLITAVFGIWSSYASSWGALCFLFACVGTGVGGNLPVDGALFLEFLPDSSSALLTLLSVWWPVGQLASSFVAWYYISRQPIELGWRSFIFAIGMITLVMFFIRFFVFHLFESPKYLLSQGRQAEAVAVVHGIAYRNSCKTWLTEDILDAVVDMEAVQRSTARLSTKEVLKQNLAAFSGEHIRPLFSNRKLGMATTLVWLCWATIGMGYPLFNAFLPQYLSHGVSTSPADGGAATMTEASNAETYRNYAIISAVGVPGSLLAAYTVDHPSPFLGRKGTLAISTLVSAVFLFFFVTFGTTPNAQLFLTCVEAFTQNIMYGVLYAFTPEMFPAPVRGAGTGVASFLNRVMGLIAPVLAAILPGDGTVLPIYLSAALILGAFVCICFIPIETRGRQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X303</accession>
    <name>A0ABR1X303_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004693</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672626.1">
        <property type="nucleotide sequence ID" value="XM_066809008.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042068"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051775">
        <property type="entry name" value="Homeobox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24323">
        <property type="entry name" value="CEH-10 HOMEODOMAIN-CONTAINING HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24323:SF7">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="65"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="67"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="162"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="252"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="430"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="594"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="646" mass="68989" checksum="62DF8B346D490117" modified="2025-10-08" version="1">MSSLHQQSPGPSPTTSIHDGIEDHRASQDASFQSSMSDPDSSALSFETSFHMESGYPVPRPENERHPKGKRKRTTAQDKTILENAYSTNPKPDKAARQDIVNRVTLNEKEVQIWFQNRRQNDRRKSRPLSPQEIAALRYGGPIHGLSGESLSFGNAPSIADDSFDTRPAEVEHRAPSPVSVGTMHSFRLSPSAANPGAKEQSNPERRASESGVSPSHSIFAVSANESAQKFSQSLPSSVGYLSNRWNASASFSSPSTLDRAGDESFRLDSFPPSAGSAVDNSPSSILPPPSSSSSQFRLSLSLEGKAELVSSQPSPPRPAQSQVLHDTTQLAPVRAPRILQRSRSALPGITLPPISTLTASLPAQLARGRSRDVHAWESCCDAETRDELTQQAENESSGSAVAAISLLRSSSQTSSGLNSLLNAVAQAASGSIQQPNPGKRNAPPSRRSSLSKKPKLSRSNSSSISRMQSLPPPAQATQQSSTDSLDKPETAATEDVDPEKKSAAKPNLAIVLSPGGDSDKENWSPGSDGNPDRRRHPLTIGDSNQRADCGPGGPNASNKRSFLGNRANTAPVPRLRGGKAGLETTVSIFEDENGQKKLPSDKSGKGPKADDEVDRFMMRGQVSPSKRPDMDCVAGLLSLSQGAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3C5</accession>
    <name>A0ABR1X3C5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell surface protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672813.1">
        <property type="nucleotide sequence ID" value="XM_066809195.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042255"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39606:SF1">
        <property type="entry name" value="CELL SURFACE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39606">
        <property type="entry name" value="SURFACE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="391" mass="38177" checksum="3B0B86342BFDAFD9" modified="2025-10-08" version="1">MSSIINKVKDAVKGDKHHEQPEGTHGTHDSRAANAADPRIDSDRDHRANPAGTTTGHSTTGTGVGHSTAGGVGHSTTTGTGVGHTTGGTYNEGPHSSSTANKVDPRIDSDRSGTHAGNLAGQGYTTGSGAEGVHGPHSGRVANAADPRVDSDRDASRTVGNTYGSSGTAGTVPHSGAHGTGMDTHGTGLTGTTGNTHGTHTGTTGGMTGSGLTGSHGNTGMTGTHGTSGMTGTHGTSGMTGTHGTSGMTGSNTHDTSGLTGSNHGNTHGAGMTGAAAGMTGAQHTGHQQSGMTAPGSGLTGASGHQAYNTGEGVHGSHGNKVANAADPRIDSDRDHRAAPGGKGTSHVGSGPGPAANTAGPHGSDMMNKVDPRVDSDLDGSKTIGNKTYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3C7</accession>
    <name>A0ABR1X3C7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672817.1">
        <property type="nucleotide sequence ID" value="XM_066809199.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042259"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013635">
        <property type="entry name" value="Ice2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726:SF2">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08426">
        <property type="entry name" value="ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="49611" checksum="418BCA5B398F22CB" modified="2025-10-08" version="1" fragment="single">LGAAAATTNAPMWWFLRIIFSSVFLLTIVLSIPISFDVGGRDSGLVYSLSLFLFYVLYSALKLITPDKSRFRWSISMVIQSSQWIVIPGLLIWSLHRFAVDANNTDWVTRTVWALGGRKQHHTWTEYFFGDGGIVEDLTIGAWDSTLRYSSPVFQMLEGFCTLLVIQAAGQITRWIVNRGRSDTWVLILLIFSASVIASSVYFLWRVALFPQVNNIDAVMIGVTVTTAFFLCAIGIGTGRGNPVESSLLFAYVVLCVYQIFTDYVQSPEAAAAAAEQESSQADFPPLPPIIMASYSTIMHMLGSLPSAVFSSLSFLHAAFQTIAPSVMISLTYRIIVFYCATRIIPAVRESGARALMDEPSLDDSDGANRLLGFLSWFSPSILIAVYTSLLLQHFSTNGDEGWTLKDGDAGGNVWRWVNVSTTMALYAIELYLGHDDDDGGVVSHWKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3U1</accession>
    <name>A0ABR1X3U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672978.1">
        <property type="nucleotide sequence ID" value="XM_066809360.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042420"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="96" mass="9938" checksum="FECAA2192F607F45" modified="2025-10-08" version="1">MHELSAGSARCSLLLLLSLTQGVLVMIPVWLERIGRWLPAPAAPTHAAADDGRERPVRSPPARAVAPLVFEHVEASVPEELGLARGSGAALGADGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X429</accession>
    <name>A0ABR1X429_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Aminomethyltransferase</fullName>
            <ecNumber evidence="2 7">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_005070</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein] + (6S)-5,6,7,8-tetrahydrofolate = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="2 7"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673003.1">
        <property type="nucleotide sequence ID" value="XM_066809385.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042445"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.110">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1400">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1250.10">
        <property type="entry name" value="Aminomethyltransferase fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GcvT/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GcvT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCVT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001567">
        <property type="entry name" value="PRK00389.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757:SF2">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006487">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="GCVT N-terminal" evidence="9">
        <location>
            <begin position="81"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Aminomethyltransferase C-terminal" evidence="10">
        <location>
            <begin position="391"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="38"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8090109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="479" mass="50799" checksum="E7C580A656F48102" modified="2025-10-08" version="1">MKLVRALQRGRKAVPSLQSQPARSIALLSRPLSAAAATSPGSAVAPQQHSPRIALTSSSSRASRRHGSSLAADEPLKQTPLYDLHLAHGAKMVPFGGFQMPVQYSSLSVSASHHFTRSHASLFDVGHMVQHRFSGPGAAAFLERITPASLGPLPVRSSTLSTLLWPGTGGIVDDTIITKLADDAFYVVTNAACRDKDLKYLGEQLAEWKKNNNNSNENAKLEHEVLDGWGLVALQGPLSEEILSAILVAPEESKLRELYFGQCRPVMVKTRGGALSQPILVSRGGYTGEDGFEISIPPADTVAVTEALLEAAGPEKLQFAGLGARDSLRLEAGMCLYGHDLDDTTTPVEGALSWVIGKDRRDPKSANPFHGAEVILPQLTPKSKGGAGVSRRRIGLVVEGAPAREGAEIVGPDGQKIGVVTSGCPSPTLGKNIAMGYVADGSHKAGTELEVLVRGRKRKAVVTKMPFVPSKYWKGTAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4R9</accession>
    <name>A0ABR1X4R9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Delta(14)-sterol reductase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">C-14 sterol reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Sterol C14-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_005343</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673276.1">
        <property type="nucleotide sequence ID" value="XM_066809658.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042718"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018083">
        <property type="entry name" value="Sterol_reductase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF52">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE TM7SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01017">
        <property type="entry name" value="STEROL_REDUCT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01018">
        <property type="entry name" value="STEROL_REDUCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12 13" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU369120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8090382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="483" mass="53845" checksum="42F1C95D2230E059" modified="2025-10-08" version="1">MPSKAKQTQPAHKYEFGGPIGAAGITFGLPILLNLFAFACNDISGCPAPSLLNPKTLSIERLKTEVGWPAEGIWGLGSWEATGWTLAYYFLSLVLYRVLPATVGDGTELASGGKLKYRMNCFASSMFTLVACLAGTIAQGAEFPVWTFIADNFVQLLTANILISYALAVFVYVRSFSVKSGNTEKRELAAGGHTGNLIYDFYIGRELNPRITIPLIGEVDIKEFCELRPGLLGWILMNCAFVAKQYRTYGYVTDSIVFITVVQALYVLDGQYMEPAVLTTMDITTDGFGFMLAFGDLSWVPFMYSTQTRYLATYPLSMGWLGTAAVSVILAAGLAIFRLSNSQKNMFRTDPNDYRVSHIRYIETKTGTRLMTSGWWGVARHINYFGDWLQSWPYSLPTGFSGYIIMNAGSAVPGAITMLDGREVIQGPAKYWGMIFTYFYILYFAVLLIHRDGRDDEKCARKYGEDWEKYKSIVKYKIVPGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8D1</accession>
    <name>A0ABR1X8D1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Recombinational repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_002138</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673749.1">
        <property type="nucleotide sequence ID" value="XM_066806453.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039513"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013967">
        <property type="entry name" value="Rad54_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08658">
        <property type="entry name" value="Rad54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="210"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="543"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8091777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="782" mass="88332" checksum="6D8B6DFEE58FA816" modified="2025-10-08" version="1">METPKATPVKLPPGPRYKASDSVDRLAKPFKCPGSATRTPTADRPARKKRRVDYKGADGDADAADKPYTNADRLALANRDANRFPVFQPKDKDKPTTLTVHPPTLGLRQGAVFVAKPLHDPSGEFAIVLYDPTVDDKPKEKPKIEDKPAEPEVKIDEPIVHKSLSEILGIKKKVEGEHPRVPVVIDPRLTKVLRPHQIEGVKFMYRCVTGMIDEKAHGCIMADEMGLGKTLQCITLLWTLLKQSPDAGKTTIQKAIVACPSSLVRNWANELVKWLGADAVTPFAIDGKASKEELTRQLRQWAISSGRAVTRPVIIVSYETLRLNCEELKNTEIGLMLCDEGHRLKNGDSQTFTALNALNVKRRVILSGTPIQNDLSEYFALISFANPDLLGTRLEFRKRFELPILRGRDADASEVDRQKGDAQTAELLGIVNRFIIRRTNDILSKYLPVKYEHVVFCNLAPFQLDLYKYFITSPDIQALLRGKGSQPLKAIGILKKLCNHPDLLNLSEDLPGCEKHWPEDYVPKEARGRDREVKPWYSGKMQVLDRMLARIRQDTNDKIVLISNYTQTLDLFERLCRNRAYGCLRLDGTMNVTKRQKLVDKFNDPDGPEFVFLLSSKAGGCGLNLIGANRLVLFDPDWNPAADQQALARVWRDGQKKDCFVYRFIATGTIEEKIFQRQSHKQALSSTVVDSADDVERHFSADSLRELFQYRGDTRSDTHDTFKCKRCKPDGRQYIKAPAMLYGDTSSWNHFVPAAMKQIQDLLLRQEAEEQEVSTVFQYISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8E6</accession>
    <name>A0ABR1X8E6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673764.1">
        <property type="nucleotide sequence ID" value="XM_066806468.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039528"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="183" mass="20035" checksum="BD7A4F236CAB5A2D" modified="2025-10-08" version="1">MLRHLPWTTLDWTRWSDLDLITRELQMGWPRAGPRLDVREWMNAAGAHTLRLYIVCNLGEVIPCARDIPFISEPGRLAPRSFTPGRRGQTTIAKIITVPGAGLDPDLSVDSGTGGYTLGLHSHIAESIYVAEAKFTSPSVFTSASIFNVGEGECFPGLGIFPRGPAVQIARFLHDSVTLSLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8S4</accession>
    <name>A0ABR1X8S4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673834.1">
        <property type="nucleotide sequence ID" value="XM_066806538.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039598"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="344" mass="37710" checksum="3C79E951991FD6BD" modified="2025-10-08" version="1">MFRVLNKNTEETGCRFISGGTAADSGFLKREVGHIYAAPEYEVCGSKGPVNPESSERVGILHGWLLVQLKDRNFRFASNKTYLGPEGVERLIENFENGPDAAAEVPPISAYDAARLRLKLTNNGNFVPMEDHLTGTIEDLHGKGKPGVKCVRVAKRGRTTGLTFGVTNAIEAVVREKVAVKRNGFGQPIGKDKSVCSWQLLVVPFPDEGKYKKQDGGVRTRFSERGDSGAAVLSIDGTFMGQVVSVGPAGPGEYNAKPLVNERKWRGQVEGSGDPGKPTRFEKGNMPHKVRLEDPELPPFEMKWTLPSFIWHGHSWGILSDGLARSQAYIFYLSDNPVIAVDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8T0</accession>
    <name>A0ABR1X8T0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673856.1">
        <property type="nucleotide sequence ID" value="XM_066806560.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039620"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="17"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="166" mass="18542" checksum="15965623070C5633" modified="2025-10-08" version="1">MTDSATHCKFTVTHYRRPEHTHEAFMKWIVEEHLPAAMPIFKKHGVLEYSLVSDVPSQPVLAVEDGSKGDHCAYTPTQFETPAPLNSMLKVSLSKTRAGWDCADFDCFIEYVLPSVETMHAVTADPDWPAALKGEDEWLDTSRALASMGQITPYLLKTGEVVNMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8W8</accession>
    <name>A0ABR1X8W8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002236</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673847.1">
        <property type="nucleotide sequence ID" value="XM_066806551.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039611"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF837">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="7">
        <location>
            <begin position="138"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="473"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="560"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="591" mass="62798" checksum="63345F814D645FCA" modified="2025-10-08" version="1">MFGGGSSSKSDSAVETPNAGKKSPSPDSKNESSSPVSIKSSDQAASGEKRSGNGSPSGRQGDVEKKRRSSGVGSKASSLIASAKNSLNFSQVGRSNSDMNTQTALQKLGKQDPALAVPQGQHNNSAGESLPGPRSTFRVGVWEDRNKKCRRTMEDTHAFLYNFLHTPAPMLAAEADAKSSKSHEPSEDGEAPSESIASQDMVETDNGYFAIFDGHAGTFAADWCGKKLHILLEDIIKRNPNVPIPELLDQTFTSVDNQLEKLPLKNSGCTAAVAVLRWEDRVPSSSSATGSQAIAPAAAAASRLRIRQSLKTVTARQRVLYTANVGDARIILCRNGKALRLSYDHKGSDENEGKRIANAGGLILNNRVNGVLAVTRALGDTYMKDLVTGHPYTTETVIQAEMDEFVIIACDGLWDVCSDQEAVDLVRESSDPGAAAKQLVDHALARFSTDNLSCMVVRFDKAALLENQKDKSLGVEGESNAPTGKVSESEKILSSTKQKIADGGNPAIGISASNSGRGHDPIPVINDNPEAFTPTTLDSAVEEEAPIPDFSDAPEVAEPPPDHADTGRLESADLPEIHLPDKVKEATKESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAM2</accession>
    <name>A0ABR1XAM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000415</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674503.1">
        <property type="nucleotide sequence ID" value="XM_066804730.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037790"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF62">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="62"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8093730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="491" mass="54112" checksum="617DD868384EAD76" modified="2025-10-08" version="1">MANDTPASAAPPTGGEEATKVMTNNTADEKPPKDAGVVDYTGVATKSDPAEIRLVRKLDFRIMPILWIMYFLNYVDRNAIAQARLNNLEKDLDMSGWQFNTCVSILFVGYVLMQIPSNMLITRIRPGIYMSAWMFVWAVVSACAGAVHSYGGLVAVRFFLGITEAPFYPGATYMLAIFYTRKEVATRIAFFYCAQILATGFSGLISAGVFWGLDGARGLAGWRWLFIIEGAITGFVAIVGFWMLPNTPLTTHWLTPAERELAHARMERDRVTEAHETNASTWEGLKQACKDKRTWLFCLMQNFHLSACSFNSFFPTVVKTLGFNTTATLLMTCPLSSSPPRRASLCGWSSGRLHERTWHITAGLAAAVVGFIWAASTLNTAARYVACFVFPVGAYSVNSVIIGWASSTLQQTKEKKAVVLAMTNVAGQVGYIYGAYLWPDYDSPRFAIGFGTSAGFALGAIACAWILRVMLIRENTKIRGSTTEHVNLYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAT0</accession>
    <name>A0ABR1XAT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000397</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674485.1">
        <property type="nucleotide sequence ID" value="XM_066804712.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037772"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045009558" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="22"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="28"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8093712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="553" mass="61315" checksum="C502195BE0C068D2" modified="2025-10-08" version="1">MKTFKSIASFVGLSQIPLTAAEPYAQAVTLEGYGSFTGTTVNSTYSGHALPAPVDAWLGIDYATQPVGERRFRTVSWPSPFGAYGKACIQDASYLDAEIQDEACLNFNVYRTQGVPLDQKLPVLVWIHGGAFVTGSWKSFDGAAFAASSKVPITVVNFHYRINSLGFLPSELFETEGLLNLGLQDQAFFLKEFVQKHIASFGGNPDQVTIGGRSAGGHSVGIHYFHNYNEDTDKPYFARAIHQSGSVTARAFPNATYPLYVRQFTEYMSYLGCPTDNKEAAMDCLRTADINQIREISTKLYNDSERNITWPFQPTQGGPMLEKFGSESGHDGTFFHVPVLTSNVNDEGKFYLPGDLETNEEFLGYMHNGSPALNAADLELLAKLYPDPATYPDTSPFAHSPNSTQYNRLSAAWSDYGYICPGQETAYRASLAGVPTWKLRFNTNASWPAWQGIPHTSDTKYTWDEPAVQHPDTSHVYHGYLASFVTAGDPNTHRYPGSPFWPRYETTGYGMDSPPAMQLVVQPDNGTRAEPDVIRREACLFWRDAERASRLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAX9</accession>
    <name>A0ABR1XAX9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Choline/Carnitine O-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000518</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674606.1">
        <property type="nucleotide sequence ID" value="XM_066804833.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037893"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.20">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042572">
        <property type="entry name" value="Carn_acyl_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF29">
        <property type="entry name" value="MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="9">
        <location>
            <begin position="188"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="541"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="541"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8093833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="794" mass="88164" checksum="05FF011A65D6D83D" modified="2025-10-08" version="1">MPTQVRIFSMPKSLGETLAGSGSASVPRSIPDLPKISSTAHEQSTQTTPPRSSKSEMPQSQGITFAAQDDLPKLPIPSLEHTAEKYLTALRPLQGPREHAETRQAVQEFLKTDGPELQEKLQQYAVGKTSYIEQFWYDSYLNFDNPVVLNLNPFFLLEDDPTPARNNQVTRAASLVVSSLEFVRAIEQDPDSRHIVVLCHGQFYWFDVFDDNSDLIMGEKDLSINLQTIIDDAAQTPIQEAAKSALGILSTENRKTWSGLRDVLLKEEGSNNADSLGIVDSALFILCLDYTEPDTAAKLCQNMLCGTNEVERGIQVGTCINRWYDKLQIIVCKNGSAGINFEHTGVDGHTVLRFASDMYTDTILRFARTISGKAPSLWKTTSPDPWKRDPDSFGDVNTTPHKLEWDMLPELSIAVRFAETRLADLIGQNEFACLDFGGYGKNFITSMGFSPDAFVQMAFQAAYYGLYGRIECTYEPAMTKVFLHGRTEAIRSVSEESVDFVQTFWGDNPPNRRECAKAEGCDRHLYALFCVWQKYVDEQQPPLSTGYTSPSDTGSEVDMSSPVGSPGKDSSVISQDGEIRTRGRGDSTGSSRSRYHPVPSIFSDPGWDKLNNTILSTSNCGNPSLRHFGFGPTSGDGFGIGYIIKDDVLSICVSSKHRQTKRFIDTFESYLLEIRRILRITNRRATSSKQTRAREIDPTKPAKGVKGFRARGRLITGHEAIRRELNMSGTRSPTEDSMAPSSEDDELGGYGFFDAGMLLQALKARGEAMDGGEAKASEKARRRDVGKKLRLVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBB9</accession>
    <name>A0ABR1XBB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674662.1">
        <property type="nucleotide sequence ID" value="XM_066804889.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037949"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="114" mass="13805" checksum="3316122D5EDCF2FC" modified="2025-10-08" version="1">MLVIVNLQWRGCDDSNVWHSNQTDCDRKPFIHASDLAQWWQRQLYFGSQLLSLKTRFHNPLDLEWRFFFIIFFFFLARLYPTDAPWNIKNFLYPTASRAGFLEHPQSFFIARKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBK7</accession>
    <name>A0ABR1XBK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DOCK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674848.1">
        <property type="nucleotide sequence ID" value="XM_066805075.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038135"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08679">
        <property type="entry name" value="C2_DOCK180_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.350">
        <property type="entry name" value="Dedicator of cytokinesis N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027007">
        <property type="entry name" value="C2_DOCK-type_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026791">
        <property type="entry name" value="DOCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032376">
        <property type="entry name" value="DOCK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042455">
        <property type="entry name" value="DOCK_N_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056372">
        <property type="entry name" value="TPR_DOCK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45653">
        <property type="entry name" value="DEDICATOR OF CYTOKINESIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45653:SF10">
        <property type="entry name" value="MYOBLAST CITY, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14429">
        <property type="entry name" value="DOCK-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16172">
        <property type="entry name" value="DOCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23554">
        <property type="entry name" value="TPR_DOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51650">
        <property type="entry name" value="C2_DOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="C2 DOCK-type" evidence="8">
        <location>
            <begin position="617"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="411"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="466"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="482"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1169" mass="128803" checksum="8FB52E6745C550F5" modified="2025-10-08" version="1">MPWEPLARIAFAVATYPFSTQSDNELPLEIGDDLYIIEQTHDGQWLRGYLLAPPSLLAGLTTAKGQTLEARVFSGIFPRSCVEIREVLGDGDDTSTDDNGSYTGGDETPHVGSDSGKSGVASIGKRKAKTPLEKYNKLNGLRLSSGASVRTDEQTGLPVAPFKREPGEPKPPAPVPMLKVGDETPTSASEPLIDEIASCLREWHSKNLHELLLAREYSTLEKLSQLIHGLDFSRRQFLHNVLTAHEYSDLREKTVWDLVKGNKLCGGEVIVRDPAQGGRVLTGDDSVVEITKLQSLMSLLDEPPKPHVELTALHHLLVDIKTFSGSSSEATTLAVYLVSKPLGGFPTAISESYIVDVPAGGTMGQMAKSSQMRTLFTDLTSTDIGDASSADTELYLVVKVRAAHQIAVGKPLSRAGTAPHTMTGHTKDKPPSTSATKASRRSFMWGSTRSAFSKGGPRLDALSEQPEERPATASAESHDGSRAPSSSGSRIPRSSSDASQTTHLTADRLVGMGVLKLNQIMKRTEETEHLISVWAPSTNLTPEKFDHDEGWDELIIHLLDSKSGQFEKSKRAERLQIHLRPFDNPDADALVKATPTQLSGVTKTSKLGFAGAPTKPRSDIYVTVNQAFLSRQNLISRFGGSATSIPNHMAGVNLMVTMEVRRKSGERIESCIFPSSNGEAVTTWKSYAVERGEAWNQTLKLSLQPQDVTNAHLVMTITDLPNVPFAVAYIPLWEQQAFIKDGPHSLLLYKLDENTQTAQPGVSGRGGYLSLPWSTRGEASDVTGPLAALRLETYLCSTKFSQDRVVLGLLRWKEQPKEDIPGLLKQLIFVPEIEVVKLLSDVLDALFGTLVEYQGQDEFEDLVFTALVRVLGIVHDRRFNLGPLVDQYAETRFNYPFATPCLVRSFTRLLSNPTDPETARKLRATLKVVRHILKFITHGRGQQKAKEAGIGITSTSPGFTKHLQTIFKALDSMMRSTAPVLVGSQTLAVQHFHSWLPELTGLLTTEEILHIAIDFMDSCSSVKGKLVLYKLILIINYSKLDLFSHPEQRAALSANTVRWIAPHWGQADEVNEQWKEQVRLCCSVLASQIDYLGAEIPDYIPKILDSYIAIQQTEIKPKSRLSLLFPASYPLPQQAHYREGLVRRGLDRALRSVIGYLELRQRNAIRTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBU7</accession>
    <name>A0ABR1XBU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000833</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674921.1">
        <property type="nucleotide sequence ID" value="XM_066805148.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038208"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF146">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="40"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="395" mass="44057" checksum="A41D6393CC560887" modified="2025-10-08" version="1">MSDTIPDEDSLPSTTPDQGKILLAVSILTNVVALWTCVMRIFVSRADKREIHWADRFVGLAMALGSVSNLFIIVETVNWDKPQAALEADFFAHPWLILGATSAKAAICFSLVPLLQVDIWRRVLEIQILVIGLVNFAFIAASLFQCQPMSSFWTPGTDGQCWALHTRHSLEYVQGIFDLFSQFYMAFIVLIVVHQNSATARRGLKWGFCFLSVANLIIAVTIMVKMYFISLTTSRDRYLPQPVGTILTVLVLNFLIMAANILPITTFFLKDGRTLLQMLREPRPATRQQRHHAESGFLVHFDAGSMMSKGDGPMRSNLSRVSSLRRRSSGSTFYVQTASPQGARGQQGHVEIDSQPRHVELDGFEHVELDTGSGTVICKVMPGETLLLSPRGRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCD3</accession>
    <name>A0ABR1XCD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
            <shortName evidence="5">V-ATPase subunit B</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000976</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675064.1">
        <property type="nucleotide sequence ID" value="XM_066805291.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038351"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18112">
        <property type="entry name" value="ATP-synt_V_A-type_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18118">
        <property type="entry name" value="ATP-synt_V_A-type_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01135">
        <property type="entry name" value="V_A-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00310">
        <property type="entry name" value="ATP_synth_B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005723">
        <property type="entry name" value="ATPase_V1-cplx_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022879">
        <property type="entry name" value="V-ATPase_su_B/beta"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003235">
        <property type="entry name" value="PRK04196.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01040">
        <property type="entry name" value="V-ATPase_V1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389:SF4">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039114">
        <property type="entry name" value="V-ATPsynth_beta/V-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="8">
        <location>
            <begin position="25"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="7">
        <location>
            <begin position="145"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="9">
        <location>
            <begin position="384"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="489"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="489"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8094291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="517" mass="57524" checksum="4BAC6D6C3392DF2A" modified="2025-10-08" version="1">MSLDPRESSSYSVVPRLRYNTVGGVNGPLVILDNVKFPRYNEIVSLTLPDGTVRSGQVLEARGNRAVVQVFEGTTGIDVKKTKVEFTGESLKLGVSEDMLGRIFDGSGRAIDKGPKVLAEEYLDINGSPINPYSRVYPEEMISTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKQAQQKGATNKGVHDDHEDNFAIVFAAMGVNLETARFFTRDFEENGSLERVTLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDLTAYCDALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLDNRGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSSEDKLSLEFLDKFERNFVAQGAYESRSIYESLDIAWSLLRIYPKELLNRIPAKVIQEFYQRSAAERKGKNKAHPEDEAQQQQEQQQEENLIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDY0</accession>
    <name>A0ABR1XDY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675595.1">
        <property type="nucleotide sequence ID" value="XM_066805822.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038882"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="558" mass="60849" checksum="173F69213663E0BD" modified="2025-10-08" version="1">MYYSVVEPYLEHGEKEGDRAYLSEILQTWSPEADPGHAIGEALHWAIFKGYNAAVQMMMDAVVSPKVQQSSDPGFTPLLAASQHGRLAMARLFWRLVGPEGRCCPLLSRRGGGRGGRGRGRGILRGGIVSQIGRGASRALTCLRVAARNNHPDLVAYFLDVWDGWTDDEKRQALNDAAHAWCDDAVAVLLSKVAYESTDIQKAVQKAVTRRTVLMESPTRPDPNPDDFESQRRLVRRLIEAGGDPEGETGSNHWPLLHQAAISPRCDGALKGLLEKGADPNRPGPQGKNALHFACSSFNPLRPQTTALDILLQHGALSEMADEEGEIALHGVAQFGSLAQLQLCLSHCRGAFPDAPESMLHVSNAHGGVPPALRCGRRTGRRHGRVPTDLGLDINATNDNGWTPLMCALSPTRLKMARGMYRTAETLLKHGARADIVTDEDWTPLHALGSWGARWQPYPDPNSEIGRLARTLLAGGAPVDVESSVIRSPSCGTRTLSDAWGFRMRVFLETTAKTTLGQDPDPIADFTTPLIWARRCHSIDLERAIEEHLVSVSIENAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE33</accession>
    <name>A0ABR1XE33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675622.1">
        <property type="nucleotide sequence ID" value="XM_066805849.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038909"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025213">
        <property type="entry name" value="Sim4_Fta2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13095">
        <property type="entry name" value="FTA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="39408" checksum="409C87D741AC601C" modified="2025-10-08" version="1">MLLYDEACIPEPRLHPFDTGGEPLVLDFIESLGSGVHAHVWKVRINGELYALKMFTNQQDIPPLPLRLRDEYLDEADEWPHFHAFPNECRAFARLKEFGQEHLAVPCYGWIEADESHYEFMDTQIDETGWSGEDDVGRKRYAIVKELLDMQTDTSCVHIRYLKSMVDTRVAKRAFKGLKTMHDLGILVGDIKEDSMCEGKHVDLSRARAAPHPALPKDFADNPFEWHVNGGAFQDARDFEELVLRKHGWNYAFPANKLWDRIFPNPDYIGKLRSSDGLSPDQVRRKCLGNGWPGHPELFSYEKAKKRFRYVPASGRKPRRPGRSRSSRHSKLPDRCELCEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEI2</accession>
    <name>A0ABR1XEI2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675740.1">
        <property type="nucleotide sequence ID" value="XM_066805967.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039027"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="217" mass="25045" checksum="1C66CBCC58E27ACF" modified="2025-10-08" version="1">MSKGVYGAEKLKAFNDRFWACSLRGRTHERIYNQLKKAPQHTQGSRLVGRIYLNSELDKFTLSDRIAHMGWRVDLCLHSFLREHEHRVRGTTRDRNEYESPHMTVRIPKNALERIRRVVKTYWVTNPGMELHICKKVSRNHRHWKLGSFKGATELYSTNMTRIPAEGLSFEQSQKLIEWKRAGPNDARPFVCACGEAKVAQQGEEAPADGEASPDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQD0</accession>
    <name>A0ABR1UQD0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dual specificity phosphatase catalytic domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_015345</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660544.1">
        <property type="nucleotide sequence ID" value="XM_066819659.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052719"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14502">
        <property type="entry name" value="RNA_5'-triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF25">
        <property type="entry name" value="DUAL SPECIFICITY PHOSPHATASE CATALYTIC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="523"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8061124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="610" mass="67997" checksum="E18099B7D88F8532" modified="2025-10-08" version="1">MESPNHADEDPKLLREHSEMKSFQTSGFTYPEIRVFYRAHPKAQELPSDPAPLPLLVFLHGLGGSVAQFQPLLASLSNNASCLAIDMPGCGLSGFAPKSWAAYSVPALAELLELVIEQYRDRTRGQKVVLIAHSMGSTLAARLANTYGPHRTISPHVIGVVGICPVASYPKGHKILRMLLWLPTWLFNLYRMWDQRGGLYSASVTRFVGPEADLPSRELQLRFNRQSRTAVFRRVAWGLLPTTADGELVGGLFGEPTWAGLNIPVFLIGGESDHQTPPTDVAHILQVLDKGDASTPAASIRFRGFAAELPSPTAAISQTSAQQPLPKSISTITDKDFERRREQLGVGEETYEESSTPRDDSQTAMPAVPEQPLQPKKVVKSQILGRPAGHGLLYTPKTVRTVSGLICNFLSENITGRFDLGWQLQYLSREGKWDVKNLAKWKKVQPVSEPICGIFRAMKTLREVDEDHSPRVFVPKYGNLIKDIIDISHDNPVYDALGLENHGIKYHKFATVSKIPPTDEEVATFVSMVDRVREDQKARANVEGWKEYAIGVHCHYGFNRTGYFIVCYLVDRMDMDVQDAINTFAEARPNGIRHSHFLDRLFLRYSGVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT85</accession>
    <name>A0ABR1UT85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxysterol binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660743.1">
        <property type="nucleotide sequence ID" value="XM_066818555.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051615"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF184">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN HOMOLOG 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="433" mass="48503" checksum="3024676DD8C4610C" modified="2025-10-08" version="1">MSLTTTSTKCTDEKKGQEQTKSAWFQFLKSVMTFKGDLTSLTAPPFLLAPTSIIEYSAYWAEHPKLFVAPALEADPEARALKVLQWFLSTLREQHSNKDENGKRKKLKPLNPFLGEIFLGRWMDDSVGVTELISEQVSHHPPKTAYKIFNKGHGISLEGHVAPKAYFSTTINIERKGHGVLHIDRHNEDHLITMPKVHVEGVMTFQIAPELSGVSYIHSSSGYVSRIEYASKGWLLKGKSNSFVATLAKTSEPSKPLYTLEGTWNKAYTIKKGGEKSKVTANVDLSGLRRTPLTVAPLGQQHPLESRRAWHAVATAIDANDIMAVGREKSAIENAQRALRREEQADGRVWPRRFFREVRISEDPVLARFADDAALQRFEGNSDNDDNEGMSWKFDEDKYRRTLQNAAEGVKSPTHTRFDSGIGLIDDEILVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU39</accession>
    <name>A0ABR1UU39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661040.1">
        <property type="nucleotide sequence ID" value="XM_066818852.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051912"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="48"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="993" mass="111518" checksum="C88546A810A623D8" modified="2025-10-08" version="1">MDNNSALVRKTLGSAVKQQTNGVATGNNSPGAKPQAHKWQQPWARPFDWALRRDIITQLYITDDLPLKEVEEIMREEFQFHATPKMYKDNFRKWGLQKNRSSEFIESFLLRTRQASATGKKESKEWKGAPFDHNLDRRMKRYLRSGSNPNAYFLAMTSLPNDSEANINPWGLSHQATTNQTLNWVTILGMALSSLRQGRVVMGFALLNHCFEKLADMLEPSIWLIFTTFYAISSLSKRDPILGNMFLRHLENLMRIRKHAFHDLLAVLGQCGADGVSSMFPTVIGDYLMDTLSREFPEEGSVTRIMRDLIQGNALPFHVYSMPAPHATVQKARNIIANKNGAIPIQSLERSGHGQHTFVLRLPESPTRYYDTGNEANIRCALPSPPLTDPGSDDIYAETCDLNLAQSETAIEQILRESPVEMYSGELSVTAQLADLAMCFDATADVSEVEEVTEAYRGLRRLFENLSLHSEDTVKYEEELCIATVEERQQTDDVHHLHQDKHISDVEVDITNFLLLLPDEIRHDLRLEKVLGSCCWTIPVVIPIKTYYPLNAGLIPPPDPHPHHISSVKELCHNTVEQILDTFEEATGFYLLINGMLQIIVPDEFDIYSALNYYPGRFGGLQVSFIAQTQTSTAGEASKYRKTSSTEWSHIFTQTYNTTESSTAATPSGSGFGNLVSNSLRPIADQGLSIGSSVRAQVNNGKSKNRPQAKLGLMTKAQNRVYLTLPTHLVTEALIDSKLDWEWPQSGFEEVRLVAGNNNAELGKVVRTFDTDARVFPDGFEHDVSIVDVSDLPATVTGGMKPHVPLEWFSDQEWASLQFNTRSVFLLDDKDRTAKSIGIRPHQFQVGPKSPSYPGPGANQQQTVGQGIFVNRQKSKRWSVREALGRGKNRQDTESELAECKRLVARSILYRVAHDYEAPGGQSGTPVCLLDESEPGMHKGKVVGFTSYMQMVQDVQHYHVEGDQLTKMLQDGRVAFYGAFKVPKEMREEHVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV01</accession>
    <name>A0ABR1UV01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014844</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661346.1">
        <property type="nucleotide sequence ID" value="XM_066819158.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052218"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF64">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044966381" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="27"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="570" mass="62231" checksum="B27467D33754FD39" modified="2025-10-08" version="1">MLRFLSKAATAASLLLSLPLIPNVAAESLPHPIEQLLRRQLPASPKGVKTITTPNNVTVRYKEPGLEGVCETTPGVKSYSGYVDLDEHTHMFFWFFEARKNPDKAPITLWLNGGPGSDSLISLFSGNLPAIGPCNVTANGTAVLNPYSWTEESNMLFLSQPVGVGFSYQEKIKGNYDNATGVAVNSSNPTGRFSGIREDYSTDRTALAAVTAWEVMQAFFGTLPRLDPTVQSRRFHLWTESYGGHWGPGFYRYFYEQNERIRNGTTGSRGVQLELESLGIINGLISARIQYPFWPEFARNNTYGISVDEFTYKLMKLNMEMEGGCKTAIDTCLLADALPQGDDAAFFCGYAHRVCNSLALGPYTLLGGRDVYDVRAAAGADDALGVDLNYTDKFSVGVNLAFGLQGDPVRDTTFHDLEWLLAKGVRVALVYGDADFICNWEGGEAVSLSLKWPNATAFAKAGYAPFTVAASSPNSTANNKTYGDTRQYGGLSFTRVYEAGHIVPYYQPAASLELFRRVLRDRVLAGGGDVLVTPTFESHGPANATATNSGWDTGAMFTGRPGDWKKRRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV94</accession>
    <name>A0ABR1UV94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661436.1">
        <property type="nucleotide sequence ID" value="XM_066819248.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052308"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF1">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="134"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="595" mass="67714" checksum="8941C0A96D702EB9" modified="2025-10-08" version="1">MPKHATQSESIGDQETKFHVTAAAYIGQTGLENPSRLRAETEVMCLLLDPGNFGGNGFRANGGPVLLRDIDRPTLFSPQIIPQQFDPDTAKSWLGYCAKHHRLLCETELESVHGLQVIDCTTFSIKSGGPGLAYVALSYVWEKSGGACGSIREEGGRKWLPEKLSAVIRDSIEVTKALGYRYLWVDKFCIDQNDPATKHDQIQHMDAIYQNSALTIISAAGIDETHGLPGVSGTARRRQLIIRAEGVTVIQALKDPQHSIASSHWSTRGWTFQEALLSRRRLVFTDDQMYFECNTMNCFESFYMPLDILHTKNKSKTYEFLRSGMFSRNRKQKFGKIVRGRLSLYNFFCRYLSNVEDYSARRLGYDEDSLNAFRGVLARFSKERHTFGHVWGIAYPDLSPRGICCFVYALAWSHAASLERPRRRSMFPSWTWIGWHGPVEYEFDDGRKLCFFIGIRGLRFGDQAGGPAVEFSELCPESRYTVLHITGPVIPFRHFAYHPTAINNQTWTMNKYPASLSWSRDGRSNAEIFQVLKNGSKWQCLYIGSHLKTSYVVILELRPDTTVWERAGIFCVEAWTWDIDDIAKGDQYLRTFAIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVJ8</accession>
    <name>A0ABR1UVJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_015045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661547.1">
        <property type="nucleotide sequence ID" value="XM_066819359.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052419"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056693">
        <property type="entry name" value="DUF7791"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25053">
        <property type="entry name" value="DUF7791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="211"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7791" evidence="4">
        <location>
            <begin position="519"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1028" mass="116691" checksum="DE7A2537057E7B68" modified="2025-10-08" version="1">MEALAAIGLASNLLQFIELGFKLAKKARGIHQSSSGSTEEDTSHLRSGDLRYCFRMCRRGSPIKPATGEDSSKGPTLQGQSVQGYNQEHLEEQGEARSGHPAGSRPKWTQYSIATSDEGTQLQSISTQISSLREDLSRNCHNTAIVTELYEVLEKPRQSLIKMRQHQILESLRFDSMRDREEGISEAHEATYDWILAPEGSFATSAHESTSRRFQSWLQQNGGIFFIMGKPGAGKSVLMKTISGHENFHRLLATPSNESQIVVAKFFFWNAGSNHQKSFQGLIRSLLHSILSQAPDLIPAAFPKEWEETKQFSGQSWTAHHDHKKINAVFEELIHSELLYRDRKLAFLIDGLDELEGDHRHMVERIRSWSSTGGDNLKICVSSREWNVFTDGFSDCEGLQLQMLTHDDMFRTAKDTLAGNNDFKRLEAPTEELEAFASSLVEKAEGVFLWTSLVLRLLQDGLSDGDEMRQLQNKLDVLPTELEDLFQHMLTSISRGVKRDRNSDPAEVLASEMQGMARAEADEYLQKKISKLRKRLTGRCKCLLEIRQSENHTPCYNESVHLAHRKVKEYIEGDQPVSLLTRFTAGIKWEADHLRTLAAHIKFMVKSGHTFIGWPHPKDPYCHQDEDCEGPSTCATENFAIWFTRELSITLAVLRYNKTSTPICIIDFLKDISTLVEHFKDEGNLFKSTCSKGAFYAKCGAAHIHGYHKIRPQRLWPFLTCSHGQDAGTHISIPHIAGFAAIPEFFGTGLSDIGFAPKQTHDSAGLIRCTAFRQFKKFDDDSHPEKRRAEILDRILDQDLRIDRTPYGCSYKNPVEKGYDWTVWQVMLCQRILGHSDELYPEDWNSLFKKLLGRGIDIKFCLRVHHSLREGHLKEYPPATYPFWDLEDGGSNTYGWVDSDRPDHGPLAIFLLAEDSKLARMAKERGGVLSLADLFEWMGIRLEESQKANIKVPLIPCLDGWKLARQMALRIYEDDKNSSCGILRRMVRDTPDILVDSKDNSDNGSSMTSDDDPNNALYMAYTRWIRVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWR6</accession>
    <name>A0ABR1UWR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylylsulfatase HINT3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661095.1">
        <property type="nucleotide sequence ID" value="XM_066818907.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051967"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648:SF2">
        <property type="entry name" value="HIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="HIT FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="42"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="134"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="195" mass="21239" checksum="A0A5D9AB2EBEDCB3" modified="2025-10-08" version="1">MGDPNQSFDPTVLPASDPCPFCTIANTYPTYDPATPPGPDEPSLDPSKAAPASFVVLSTPTLLAFLDILPLSHGHLLLCPRRHAPKLTDVDAREAAELGRYLRLLSRALVRTTGVNDWNVVQNNGAAAAQVVNHVHYHLIPRPEIRASGKLRESFTMFGRGVRSELDDDEGAALAAKLREAIREVLEEEGRKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXI9</accession>
    <name>A0ABR1UXI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014862</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661364.1">
        <property type="nucleotide sequence ID" value="XM_066819176.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052236"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047207358" evidence="7">
        <location>
            <begin position="21"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="501" mass="56077" checksum="0EFA20BA52B93759" modified="2025-10-08" version="1">MLQAVLWALTLIAASCLARAVYNVYLHPLRGYPGPLLCRATFLTWMLVQCRGESTNFVHAQHKRYGPVVRLEPNLLSYNDGQAWRDIYGHKTGANSTTVGNLPKPPYAVRTNPNGYSDIINVPTEHGHRRMRKLMTHMFSAAALAGQEPLIRGYVDKLVATLQSRAGEPLDIGLCFACTTFDVLGALAFGKDFGGLETGELHPWVTNIFGSIKQSYLQRILNRFPWPLNRIAYRIVVDDELSQARKAEFNFATERARERLERGITMEKHDFMSYMLKYNDEKGMSEGEIMSNSSILIIAGGETSAVYLSGIIYHMLCKPSVMEKLAGIIRSTFKSEDEITFNALSEIEYLSAVIQEGGRTYAPVPSGLPRVATKGGSLILDRHVPEGTVAYVHAMAANLSPANFADPEDFVPERWLKQPPAKYADDHLEATQAFSLGPRGCIGRNLAMAEMRLILARVLWNFDIKLCDESKGWKESQKTYNVWDKTPLMVILTPRVPHFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UY74</accession>
    <name>A0ABR1UY74_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vitamin H transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661332.1">
        <property type="nucleotide sequence ID" value="XM_066819144.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052204"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF38">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="224" mass="24318" checksum="168E8238DE6EDC86" modified="2025-10-08" version="1">MADPSRFDGGEDRPKLSHFQALKVALTDWKVWLFVVGYMAVVGSSTLSYFYPTLVAGLGYSTVNAQYMTIPIYVVAFVVTIVVVVFMDKYPRWRGLVLGCCMGVACLCAIITCAVYDFKARYALLVIMASGLWASNGLSLAYASSTFTTMTAEVRGISLAFVNAMVSNAAIAGNLAQIYGSYLFPSKDSPKYLMGFGVISGLCFTGVVAYLALFVLLKRPTARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1D8</accession>
    <name>A0ABR1V1D8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DUF605-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_011742</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VTA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8064995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661749.1">
        <property type="nucleotide sequence ID" value="XM_066816057.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049117"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.270">
        <property type="entry name" value="Vacuolar protein sorting-associated protein vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044538">
        <property type="entry name" value="Vta1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039431">
        <property type="entry name" value="Vta1/CALS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023175">
        <property type="entry name" value="Vta1/CALS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041212">
        <property type="entry name" value="Vta1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04652">
        <property type="entry name" value="Vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18097">
        <property type="entry name" value="Vta1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vta1/callose synthase N-terminal" evidence="10">
        <location>
            <begin position="14"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Vta1 C-terminal" evidence="11">
        <location>
            <begin position="389"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="155"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="302"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="330"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="343"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8064995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="425" mass="44902" checksum="40A339AD9F71E922" modified="2025-10-08" version="1">MAANIPAPLKQAGITPFVVRATQLEKAKPVIAYWCEYWVVNQILAKQLHSTDDDCLQFTMALMDKLEQTKSEQAGNDAILDDVAGKAYVEQFAQETLERALRPLNANKVTQQTAVTFEAAATFFHLVNIWGPADAETEQKIKYAKWNAARILRAIKEGKDPNESNPKPQEEKAEEQLDPNDPEVQALGGLPRSATVEDAPEEADKNYLDPKASAISPATVSAPTSPPHSAIPPEQVSPIAPPDQPTHDGYFPSAPSGSAGDDPPLQLPSAPGAPSLSGLERASRAFGGHLTANSAGHAAVLLPTAPAPVHQPSAPKAAPGPGLPPPPQNFTPSQPSAPPASSFYNQAPRQPTQSSGPTRSPPPAQQPPASSYSGGPPTNSVYQADDMSIVQAQKHAKWAISALNFEDVPTAVRELKAALNALGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1Q6</accession>
    <name>A0ABR1V1Q6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011888</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661895.1">
        <property type="nucleotide sequence ID" value="XM_066816203.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049263"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="197"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="27993" checksum="C3C3E4E4DFB10B1E" modified="2025-10-08" version="1">MQPGSGNPDRGYTSVPGAAPTPDSRLRVKNGEREMIFDEIKKMLPHETAEREAAIQAKFATIDDMVRAIAERETMSPEEILALATNQSGFTLLHVAAQHGRTEMLDYLFREHMFANRLALRTTMLLARNVTLDRPIHIAARSDCVDFIRGLVARGVTIDSSGAAGFTPLHFAVQGQHRQLVADLVGMGANLNVQNMGGETPLHLAVHKGDAEMVRYLLDNGADATVRNAGDSTPGVVARGVSNSEVHQVFVTRDLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1X1</accession>
    <name>A0ABR1V1X1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661954.1">
        <property type="nucleotide sequence ID" value="XM_066816262.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049322"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047482523" evidence="2">
        <location>
            <begin position="24"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="21856" checksum="75075C0750C72E96" modified="2025-10-08" version="1">MSPIHFSLRQAAVALLIASSAASAKQAESDTQELAHAAAADACACPPPPACAPCAAAADVSTGLTQSGPTNSSAAAAAAADHADLSAEVDEEVDAATSAAATEEDEGESDEEDDDEDDEDEDDDDEEDDDDESDDEDDDDDEDDEEEDEEEETQSADFTTAVTAASGKRGLRVGPAEKRGTETGSADFAAATAVSARRRAAGRYARAAGSHWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V215</accession>
    <name>A0ABR1V215_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661999.1">
        <property type="nucleotide sequence ID" value="XM_066816307.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049367"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="209" mass="23586" checksum="A7A0AB205C49BF0F" modified="2025-10-08" version="1">MQLKDFFGDMQGGKHAFRENFYAVDLHHEEHPFECSPSPDLDAQKTWSDRWSSVLLDKKKLENESNAASRASTTPDDEIGGNQYKRQVREQEAEIDELKHRIRGEKVRAKSQASALAVKEAEVLVLVNRLQLARAAARATVTDDCKSDQSSPFSTLNHTPTSSQNSGSSTPGWFVVGNDQQEESSAEKEKAEKAKKADWDEYVNDITWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2Q9</accession>
    <name>A0ABR1V2Q9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662206.1">
        <property type="nucleotide sequence ID" value="XM_066816514.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049574"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021460">
        <property type="entry name" value="DUF3112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184">
        <property type="entry name" value="YALI0C10208P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11309">
        <property type="entry name" value="DUF3112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="340" mass="37620" checksum="6909B131CCE4CB9A" modified="2025-10-08" version="1">MSGPPYLPNNASLGGRPTVDVDVPISAVLLAIFLCLAVVHMTIFQKNRRRDHKFVFSGMLFGLSMARTAALTMRIVWACRPTNVRIAIAANILTQAGVIILFIANLFFAQRMVRAYHPSFGWHTATTMALRFLVFCVVACLVMVIICTVHSFYTLDMNARRMDRDVQLFAGVFFALLAFIPAPAFGAGRFRSKVQLLLFTSLLLTLGAGFRIGVNFDLRPANAPAWFHHKACYYTLNYGIEIIVSALYAAVRFDRRFHVPNGAKGPGDYRKGGVHIATEEEAFGPADSVETIRATHSQEEWERQAKKEVRGEDINGLMMNPAATKEGGRGTTGKSDVEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2S2</accession>
    <name>A0ABR1V2S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662237.1">
        <property type="nucleotide sequence ID" value="XM_066816545.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049605"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17731">
        <property type="entry name" value="BRCT_TopBP1_rpt2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059215">
        <property type="entry name" value="BRCT2_TopBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="6"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="358" mass="40014" checksum="E28C172FF7331713" modified="2025-10-08" version="1">MSLVAQPKPIFRGLVVATTGNVGQGRKGWSESDIQRYLESWGGRYSPDLDASVTHLIAIPEELQPKNRSVNVNSALKRKNLTILSLDWLEDSFIETRKLPPDNYLLAKGGRSIAESTRAKRLREQKKAAKEDEMAKTYPHPRLFIAYTDETFFRYEIVLTRDQGERYTLTLFESNAKPHMYHVGYIFYRSKGAKPIRDRMEGPEAGGTFDAAFKEFTGFFKRQTGVEWDDRVAAFRKGKNNVTGRGFVYELPAGGKPIGLIKGEVPDMDTLYPSDPTDYVPSHPEEESKVEEEAKGAQEEESADPMETTTAHNGNTDMQNAGDSVIIIDDDSGVDDVDEPSNTAAANDEPVDEGYESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2U5</accession>
    <name>A0ABR1V2U5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012262</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662268.1">
        <property type="nucleotide sequence ID" value="XM_066816576.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049636"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF27">
        <property type="entry name" value="CHOLINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="20541" checksum="EE14A7CD48191DB8" modified="2025-10-08" version="1">MVCIGLTVIGLYMTAGRTLWTLARDGATPFSGHLAHVNPRFQVPIASTIASACLVTVLGCIYVGSSTAFNAFVGSFLLLITSSYLAAILPNLLTGRKNIRFGPFRLRGWLGFAVNGVACAYMMVWFVIYSFPPALPTDGQTMNYACLIWGGLTLLFSLWWFVVARHGYRGPTTTGGLSTVHEGRSVVPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V305</accession>
    <name>A0ABR1V305_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mannose-P-dolichol utilization defect 1 protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_012312</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the MPDU1 (TC 2.A.43.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662318.1">
        <property type="nucleotide sequence ID" value="XM_066816626.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049686"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016817">
        <property type="entry name" value="MannP-dilichol_defect-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226:SF2">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023381">
        <property type="entry name" value="MannP-dilichol_defect-1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR023381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8065565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="30205" checksum="4B1FF96D699C4B7F" modified="2025-10-08" version="1">MEALKTALEPLKPLTSSLPAPIRDLGVSIIGDTCYKTLILDLDPTATECVKLAISKGLGIGIIGASSIVKVPQIIKLVKSQSASGVSFLSYLLETSSYLISLAYNVRNGFPFSTFGETALILCQNVVITVLVLNYSGRAGIAALFVAALAVSVVSLFTETVIDANALSYLQAGAGVLGVASKVPQIAAIWQQGGTGQLSAFTVFNYLAGSLSRIFTTLQEVDDKLILYGFIAGFALNCVLAAQMVYYWNAPSAKVRGKMKEAPVAAAPASSGSSTATPKSKGPTTRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3B4</accession>
    <name>A0ABR1V3B4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hatpase c domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662432.1">
        <property type="nucleotide sequence ID" value="XM_066816740.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049800"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022155">
        <property type="entry name" value="DUF3684"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058210">
        <property type="entry name" value="SACS/Nov_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF047352">
        <property type="entry name" value="P_loop_sacsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12449">
        <property type="entry name" value="DUF3684"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25794">
        <property type="entry name" value="SACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacsin/Nov" evidence="2">
        <location>
            <begin position="27"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1400"/>
            <end position="1506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1706"/>
            <end position="1732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1404"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1706"/>
            <end position="1717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1732" mass="191299" checksum="C04D0705E60485C8" modified="2025-10-08" version="1">MDYGRLRAAALNHGEDEEAVTVDTRALIDKVLARYSGEWTTLRELVQNAADAQATTVKVKWETLPSTSVPLPSTPDRSELLKHIIQHHTLRRLVVSNDGQPFTKTDWGRLKRIAEGNPDETKIGAFGVGFYSVFADCEDPFVSSGSEAMAFYWKGNALFTRKLLLSDEQKSNDTAFVLDYRNTTTPLPNLLSVSQFLATSLTFVALQKIEFWIDDYEILSLRKVTSPSASVALSRDVDPTTKDRLMKINQVDRSSAQIDASYMSAIGWKPQVAAAKTNEAYGLKGCQGGEGDPRGYCRRHHSHLDLYHLLKVTTAAIKTSVTSGFSAELERATKKPPPKVAKLAILTSSYDETAASESTKDSGAISKAADVFASVLPSKKPGGRIFIGFPTTQTTGAGMHISAPSVIPTVEREAIDLNARWVRSWNIEMLRAAGIMTRLAFAHEMEELERKLQRLVETPGGKIGPKEVARCMPEALHILNSFTFGDSTPSGQVSQIIEEAFWTCYRKPYIEIYSTRGVRPTTQVRIGSEELSKFVGGIPVVPSELKDLGFVKKVTDFDLLSRITVDDVRRELSEYPMNRDQLIAFIHWACKTAVQGELDPADKDRLFDAAIATVSQDGSEQGGIITLGTIRNYLSPNKIPAGLPIPPTTIPFEFTSKCNSNELQALGWESLEIVPWLRFLLESGSSRPDNLNLTKSAPFAVHILTVLSKSWENLSQSSRGTVVSLLQAHTVMPTKVGMKKPTDSYFPSVKLFDDLATIQGCHGLKDKFLNALGVRKTVDLDTIFKRLLDPSIDEGSGQPKWSHVELIKYLASVQADIPNNDLKKLRESRICPAEAGPSGLESGKGTTQLYKVSELFEPKAALRSLNVRVLQWPGSNAGYRPGSVEGRFLTALGLRPYPSVPELVEMMSSSDQTLRENSMDYYITSHVSNGYHTFDISSTPRAFLPLEGRPELVSPRGCYTNTAASILGFSILKKELHVHANKFGVATNPPIMECVNRLISNPPLSQKAAVPFFEYFASRQMDLPGPPVAKLRDAAIVPVVRKRPSSEKPISAVSHISPSNCFLGTSATYGDIFDFVDFGQQANMFLFSCGAKNEPTKLEIAQLAATEPARLLSVFQSSEKYLNLLRSLAEDYPVLKRDKDLWRKMKSSRFLLASKEISTPKEKLIEVDEDEAPIKQYQLAAPSDIVILDDYIGYRLFKDRLICAPEEDSLEAFYTALGSQPLGSLVSEDLKVGATNEKQEGAVWLRKHVLERSKIFIHEYSKYTRDPIKHDAKWLEKNLNVEVVRSVALRRTLRGTGQTHTEDRSAASARTANGWVLYVASKSSRPDMYQVGQAICQLILNRPSQQAYTFFEPFLKLDLLDLRSRGYNVDRILRAKAAEARIAEEERRKALEAEEAAIREREQQFQQQTQAATATAAARERNRTPPPRMPGSFESPDSPPEAAVTQNRKSRGLFSNLSKRFGFDDSGDKDEHLQSFLDPPQAPESSKTPVQGPKPNKSHGDNGKVTNPAVIQQNLLNAVKATRGHNSSSLFAPPSTTEVKEQATYCDSTPLQNLDFAAEASNSMRVFVSKGLSVDLGQFLSANHSHINAFAYLLREVGGVYSIPATALHIFYDESGGTIAFNSSGSIFCNLRFFVQLHAADYGNPQQKAEAGVWWWVVIAHELAHNIIQLHNADHSYYTESFIQQYFPKMMVKASELMGSAGSRASLSGPPAAASSAGGQGQVGAPPPYAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3L6</accession>
    <name>A0ABR1V3L6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phytoene synthetase/ ribosomal protein S6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662526.1">
        <property type="nucleotide sequence ID" value="XM_066816834.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049894"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15465">
        <property type="entry name" value="bS6_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_bS6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="Ribosomal protein S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="150" mass="17142" checksum="E241E9623B6E0117" modified="2025-10-08" version="1">MQTLPKTHVTPACFHPRFSALIPSSRDDMQKRERLTNTRLFVFFFRRIVSTTGALILRERGVIRGLSNWGVFSLPRAVSVHQMRHTTGHYFAMRYDAGVDTQKSVSKVLRNDPRMIRHTSVKLGDGKLDTMSRIGAIGWQRLGMGDEKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4M9</accession>
    <name>A0ABR1V4M9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DnaJ like subfamily A member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012875</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662881.1">
        <property type="nucleotide sequence ID" value="XM_066817189.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050249"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="12"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="144"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="144"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="390"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="14"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="424" mass="47168" checksum="17C127A7897506F4" modified="2025-10-08" version="1">MDFPGAQEEEVDLYELLEIDKNASQNDIKKAYRKLALQHHPDKVSEELREESEAKFKSVSQAYEILKDEEKRAMYDQHGMAAFDPSRGGGMGPEVDINDILAQMFGMGMGGPGGPGGPGGPRRPRRGADEESRYNVTLEDLYKGKTVKFAADKQVLCSTCTGTGGKKDVKPQTCEKCKGNGMVEAFRQIGPGMMTRESAICDRCEGSGNFFKEKDRCKKCKGKRTVKERKPLEIYIPRGSMQGERIVLEGEADQLPDQKPGDLVFILVEEPHDVFHRIGNDLSADLEITLEEAICGFSRVVLAHLDGRGIQISHPRGKVLRPGQVLKVEGEGMPLKRGESKGDLYLIVKIEFPEDGWLKDDIEYEGLRKLLPGPPEPIKAEEVDDVEYDDDADIEDMGAQSGDPRYQSEWADEDDEPQAQCAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4P9</accession>
    <name>A0ABR1V4P9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662640.1">
        <property type="nucleotide sequence ID" value="XM_066816948.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050008"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045360771" evidence="1">
        <location>
            <begin position="22"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="97" mass="9443" checksum="0D22F9BCF7128B1C" modified="2025-10-08" version="1">MQFSALTALFGLLMTVAPVMAAPAEEVNTLDRRGTCGASAGAPIASFPIGGSCSGSGFGCDTSCHSIVQCANGQFVLIASCGGNNCAGNHNGGAVCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V511</accession>
    <name>A0ABR1V511_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661842.1">
        <property type="nucleotide sequence ID" value="XM_066816150.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049210"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="130" mass="13888" checksum="077C5C3618163ADF" modified="2025-10-08" version="1">MPICRLRALPTEGPHRLDARGPPSSCKQAYPRGCAHRRPDIVRQEAKGGGEASPEPYPESHDEYGGTHGIDQDIAPGVDWASNEALSAADSNLYIDPAMLDNTGDSSSSDGYACGDFEPAQIYPETNSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5A8</accession>
    <name>A0ABR1V5A8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PQ loop repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013115</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663121.1">
        <property type="nucleotide sequence ID" value="XM_066817429.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050489"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052241">
        <property type="entry name" value="SLC66/Scramblase_ANY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14856:SF9">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14856">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="268" mass="30051" checksum="77941EF8FE9C6BB4" modified="2025-10-08" version="1">MGNLLTTLTGFAAPVFLILSPILSYADQAISMQRKRVFYWPGAHYDTALLIQSFCNIFMQLILLKIALDHRPAHSSKGGEAAVPFAGTQDGHSGFQRPYGFWQWRSHKPYWQSLLYFFIGLTVLELLLAPFSGIYPAYSSFIGYVGLSVEATLPIPQLLANARTRTSRGLRVSVLASWIVGDMMKMFWFFTSTTEIPWSFKICGMFQAGCDLLLGVQYLMWGSRETPAGLQQRWTYAGVRPHLQGRSPSGLGSPMTIDRRSPFAEKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5F0</accession>
    <name>A0ABR1V5F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNase1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663183.1">
        <property type="nucleotide sequence ID" value="XM_066817491.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050551"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045201637" description="DNase1 protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="19830" checksum="F881FA48D5238BE1" modified="2025-10-08" version="1">MRFTANLAALVAAAASLASATNTITFKNQDSTPKSVVFTANPGFQSLDKIKVDGNGEFKVTIPQGWQGNYYSIAEGSPNNPGMLGEVAFQGWNDLTYFDVSAIVDATDVDGVKEIFPATELLAKTKMAVSGCTSFPCNTAYYHPDDIQTVSTKETNLITTLGGGNAAPSKRDETNLVARKFVLGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5M5</accession>
    <name>A0ABR1V5M5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663258.1">
        <property type="nucleotide sequence ID" value="XM_066817566.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050626"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="278" mass="31892" checksum="4BBBEC9E756CEF90" modified="2025-10-08" version="1">MPTAQLISARGRTKPLRQRVRTTDKTPEVVVSGRFGLTFHQVYNCRSAASWDGDLALSATHIPERRFTFAVFYGCDAKTRENLIGRLQKNPKRVMHPMTLPLLFADIERGRHTELVHKFHSMLMQRACDFSNDSRRDSEISHTPSPSSASASSSMIEKPTEGLLRPERDSETMSQWMELYHLRNGLENWKAQLQNLAEHQRELRCAYPPSHVSHDTTFEQENLRRCLAHQGAQIQARLQQLLLEYDEKIRQSSLIIDGMNFATQVVSGFCPEHLSYVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6E3</accession>
    <name>A0ABR1V6E3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662563.1">
        <property type="nucleotide sequence ID" value="XM_066816871.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049931"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="330" mass="36488" checksum="50E036534488BABA" modified="2025-10-08" version="1">MVVNRRKKNIRPSREDVASREPNILQMCTMKFGYPGTPPSEIKRPHLKRQAEAFAGGDPFFDEQGERSPKKRRIQSLPIGLPKDKHILLCRGSAAAARRYRKIPDSSPTTAKANTNAGRKSKQLITADESTTFGRLDLFAWQTDYIQTSSSLATPKSKKRHPLKNVGAWLGKSTASPAHALAQQFSGDGLLDGILGTSTTLTKSMALRRQQPLRQRSLNMPAKTPASIKIPHTPTKVTAYKDVTRNVSIEVMAMGCDINEPATPGRQLRSSKRAREDTEEPGTAPCTTTRTPRKRIKKTPSPPPIPTVVTRSMKREMEARGVYLSLMALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6J0</accession>
    <name>A0ABR1V6J0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2OGFeDO JBP1/TET oxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013567</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663573.1">
        <property type="nucleotide sequence ID" value="XM_066817881.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050941"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024779">
        <property type="entry name" value="2OGFeDO_JBP1/TET_oxygenase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12851">
        <property type="entry name" value="Tet_JBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2OGFeDO JBP1/TET oxygenase" evidence="7">
        <location>
            <begin position="255"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="387"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="466"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="495" mass="56157" checksum="583354FDAD4FAA8D" modified="2025-10-08" version="1">MTIQIQQIVMARRLLRLEGGLNAAMSAIPIDDSKRRDQVLGDLRSEAREEYWLHSTKSQRDLLRYSAVMLHSPDVQRLVDIIKSHWSQEWNNGRYDVDFFYHYLADKTAAELVWELVDVDLFVVTDCNRRVVFASLENATGLVFDDGLAQKLANTVDMYSYFTPLPLPESRRHVLDRYVRRLHPELDPANATVEQLHRAKMAVVHYGRWAMQGDPHGKRVVPTRDTCFNRSGDPPYNQMDVFPGFCRSVLGRCGDVVRFLLRNLDPELYSLYHSVYDNLPGQHRLDTTDDDFLSLFAVGINGYTQRHRDTNDLAGGMAGLVTLGSYTGGNLCIPQLGFRVRYAPGACAILRGDKMDHLVTDYSGPRYFVIGTHHESMRRHAMRKLREMEAARQQQAHRESEEKKDEEQEEQATGSAPSRPPQNPDPFAPADCRAHDETAPDDGLAAGVFVETPCVNPGCDDDDEEVANRKWTNEELHEAGALPMYDDSNSDSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V704</accession>
    <name>A0ABR1V704_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013459</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663465.1">
        <property type="nucleotide sequence ID" value="XM_066817773.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050833"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF57">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="519"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="563"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="595" mass="64527" checksum="ADA5506A2D6CA60A" modified="2025-10-08" version="1">MSVLHEYDYIFAIGTLFAFLDAYNNGANDVANSWATSVSSRSISYRMAMVLGTIFEILGATTVGARTAETIKNGIIPPDTFKDNAPVQMMAFTIALVAASSWVMWCTRHSAHVSSTYSLISAVAGVGVATVGASKVQWGWNNGKGLGAIFAGLGMAPAIAGGFGAAIFMMIKLIVHMRKNPAPWAVWTSPFFFLVAGTICTLSIVYKGSPSLGLTKKSPEFLASVIVGTGAGVCLVALVFFVPWLYARILKRDSSVRWYHIFMGPLLLKRPVVAEADRAVVPRYAVVQEDDESMRSSNSIKQNGEQEKGNDHERTMVVTEGQMPKTYKEIQEEGDAKLRQKLLEHRGPIGWAMRTLRDNPMGPGQIYEKKNAKTALKRLPAQITAALLYGFHYDIHAAQTGIAGTPDGVRMQRVYDAAEKYPDEVEHTYSFIQVLTACTASFAHGANDIGNSVGPWAVIYHTWSTGKTADKTASVPVWQLAVLAIWISIGLCTYGYNIMKVMGNKITYHSPSRGCSMEMGAAITVLVFSQYSLPVSTSMCITGATVGVGLCNGTIKAVNWQRVGLLLLSWIMTIPIAGTFAGCLMGLFLYAPHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V793</accession>
    <name>A0ABR1V793_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Elongation factor Tu</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_013809</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663815.1">
        <property type="nucleotide sequence ID" value="XM_066818123.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051183"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF36">
        <property type="entry name" value="ELONGATION FACTOR TU, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="53"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8067062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="440" mass="48487" checksum="4A9662A03CB7D33E" modified="2025-10-08" version="1">MSAAFRTLAPFLRASRLSLRTGSTANPLQSIKSQNVSAALNIYRSYAVYERTKPHVNIGTIGHVDHGKTTLSAAITKRQAEKGMASFLEYGSIDKAPEERKRGITISTAHIEYSTDNRHYSHVDCPGHADYIKNMITGAANMDGAIIVVAASDGQMPQTREHLLLARQVGVQKIVVFVNKVDAIDDPEMLELVEMEMRELLSHYGFEGDETPVIMGSALMAMEGKRPEIGVEKIDELLEAVDSWIPTPERDMDKPFLMSVEDVFSIAGRGTVASGRVERGLLKKDSEVELVGKGGEIIKTKVTDIETFKKSCDESRAGDNSGLLLRGIRREDVRRGMVIVKPGTVKAHTKFMISLYVLTKDEGGRHTELPPQMFLRTADESCALFLPDDCEDKSRMIMPGDNVEMVAHLHNPIAIEAGQRVNVREGGRTVATGIITRIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V835</accession>
    <name>A0ABR1V835_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664117.1">
        <property type="nucleotide sequence ID" value="XM_066818425.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051485"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="RDRP core" evidence="3">
        <location>
            <begin position="54"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="4">
        <location>
            <begin position="1157"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="5">
        <location>
            <begin position="1233"/>
            <end position="1450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8067364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1487" mass="165949" checksum="D482BC697F3EAB27" modified="2025-10-08" version="1">MAPRFAQDVARRLRLSFRDRRYSPSVFQIRYRGYKGVVTVDPTMREGPTWLKFLVVLLRSLGISSSTLLRKQNEHLVFLAEAVRNPHQAFRFLCYVGRPELAERVLLDSLDAVRPQITGLVHAEYDKMLNKRDEQRCRILVPQSRLLFGVCDAWDVLKEGECAVKVTRDGDGLPYALKNTEVLVTRNPCLHPGDLQKFRVVENDALSHLVDCIVFPTRGRRPSADMMSGGDLDGDTFFVCWDSDLVPSRLSQPAEYPGAREPIKFNPITDDDRLLYFAKYTNASLGRVKNLYLDWARVRDPMAPECQELNRLFSQCVDGNRIKVPPRLEKPPQPAVDTPRFILDELHEAAKATISRNRTRPADIESLGFDALELLLCRDDIATSEFELVKLVARWCRKHNASLVDFLPYFDLNALTAEEKNWILAYLPPLHGLPSLVLNALRFSNIVTEHEISQFKLNDHRLGWKRVYDSTQDRLGTFLDTTAKTLELFHKKLIVLQVDERLALAIYVPQKVEKSQDCLVDDSVRVFAFPQSKEPGTSSRLSLPTKKNYRLYCDDNLFQLFEGQRANTWIFIGRGASDDSAYRNTEDKGDRWRQRQGTLDSGQNFDCRVSVALNKFSQGLQRHIGRVNRNGVLAAEIYVISNRDIKSMKNLDLWLQYIETGEVIPLFEQDPKDYSLPTLAKVDWSDVPARTRRLAQDGDLSVLGEVHSATQLGEAFRWLHEHSCTSRVQESFDYILSHISNPNTTIGVTEWRIDALLDHIRFTPSLAAKFTGLDSWSDRTLPEVIATKLQNRGPDILKALILSANEAGELVIPPFEAALSQLHSLSFDSFSSLVELCASTVKSPELAMDLLLQCLERESSRLLYGRPAVIAHFTRNIVAIALDHIAEAQEQKVAREDLLNLKALPEEDRDGYPVVEVAFRIDAKGSPETSAHVRFTVASPPANRPIARPVSIDALVVQSQQGLAKFQCFHPLPAFLEQCSWTLTYCGSFVTSQTMLDAMRSFANLDEEVCGVSEELLGLGPPSSTSDSEVGEMKPFDGIPRGKLNASQLEAVNAALTYPLVSIWGPPGTGKTQTIVEIILGLQSMFPDQRILVTAPTHNAVDNVMRRYLDVRGKEGPVALRVSTEVRKVAEDLRKHTLDGMAGAEIYSNHAAMREAKKRIQSCQIAFTTCIGAGIGLLRSQNDFDIVIIDEASQQTEPASLVPLTKGCRRAVLVGDHVQLRPTVQSVTAALGYDVSLFERLYTSCGDGGRGGRSGGNQKTCMLNTQYRMHPSICAFSSEEFYRGELRTGMAAEDRPLPASAFPWPKAALDGGSLDVARTLFIECAGREDLGQKSKRNRGQADLCRRVCQLLSDIPTIARDTGGKHKQQSIAVLTPYTAQMTLLKTTTLSGLKGDIEVSSIDGFQGREADIVVFVTVRCNERGEIGFLKDLRRMNVALTRARAGLIVLGNEATLTGAGGGAEKETGDDESKGMWKRLLGTLTRVELEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8K7</accession>
    <name>A0ABR1V8K7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663389.1">
        <property type="nucleotide sequence ID" value="XM_066817697.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050757"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="243" mass="27238" checksum="7D2D52F1D5B3FE7D" modified="2025-10-08" version="1">MRGSEELLGEKLLLSAINSTPNNTWFIYCPKCQLAYLIGSEGRNEAANHPAHLTQSDPQQRSIAVFIDGVNEHAAATNHNNNKDTDENQEESTWTGRFCAYYGPHSRYNGDTLLTAYRDESHLLYAALSTTLAYFAHQVPRRRLRDVKRHAVTNSHRFLRDCTVFRLLVLVGPGLHKFLPLLGPVAEGPVETEALLAAQAVRWKWNAARLKAKESIAAEVRNLAEMGILVEWCEFVGDVCPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8M7</accession>
    <name>A0ABR1V8M7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664005.1">
        <property type="nucleotide sequence ID" value="XM_066818313.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051373"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="247"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="706" mass="79513" checksum="E513ED5EF6D45E9E" modified="2025-10-08" version="1">MMEVKPQVWLDSMLGLPNLPSSPPSCAVCDNLFHVMHGIYSDKLPFSWEVGSSGKETCARCRLVYIGVSAVLPDIETWDHVRLYGRLVTKNQQGKENEDTFFRVGVYNPDPVLGIGPSIIWIDFHFNPHDGIVPGVGLYTHLFSPLYHACDVIRRRIRTLYYYRRLTRCLLLAAQAQTLLHVPAPPGSEEWYQLIKSWLSDCDAHHTECNSGGSSKLPKRIIDLEFEGGAGLDVVLREPDHDDNAPYIALSYCWGSGQNLTTTKDTLDSHQTRVRWDDIPVLFQDVMKIARALSVRFLWIDALCIIQGDEEDWEQEAQKMASYYGNAWMTIAADHAPGVGHTLLPAQKSPAMQLEGSFAANGSTILVHRLPIQFDMTDSLQSGNPSSLTLFTRAWALQERLLSRRTLHLGPEEAMWECCSAYWCECGRPTDPTGDGLEFAYVTPLRQTHHEALHFLMREQRLDDQWEDVLGKYLTRKLSFEDDRLKAIASLAKNFKATDEMLVASAAKQGQVRRPQLGNYVYGLWTATLPGALLWKLYDHKNGNLRNYKFPTWSWASVTRAREHARAPGDDFVPEATVLEVPVESWDIDSQNGATDVSPPRIVIESLAVKTKWRYVSATGEWVLLNPKDGEPTDAFLKMLPLDGATDIDVACVKMGEMGVFRTIYPGLLLEPSALFPGQYTRVGSMWSFQNWFEAHGAVVGKYSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8N5</accession>
    <name>A0ABR1V8N5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S ribosomal protein L38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663086.1">
        <property type="nucleotide sequence ID" value="XM_066817394.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050454"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002675">
        <property type="entry name" value="Ribosomal_eL38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038464">
        <property type="entry name" value="Ribosomal_eL38_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01781">
        <property type="entry name" value="Ribosomal_L38e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9678" checksum="DA84A6E885D5886D" modified="2025-10-08" version="1">MPQEIADIKQFIEICRRKDATSARIKKNKKASQTQTKFKVRCSKHLYTLVLKDTDKAEKLKQSLPPTLQIKEVAKKNKKGKHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VBT8</accession>
    <name>A0ABR1VBT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014145</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664151.1">
        <property type="nucleotide sequence ID" value="XM_066818459.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051519"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023041">
        <property type="entry name" value="Glucose_rcpt_Git3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11710">
        <property type="entry name" value="Git3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045594417" description="G-protein coupled receptors family 1 profile domain-containing protein" evidence="6">
        <location>
            <begin position="17"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="3"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8067398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="364" mass="39688" checksum="CF89F711335660CA" modified="2025-10-08" version="1">MIGSILSLLATSVALIAHFVAPPGRHFRHALILNLLIADGMNSMNNSISGVITMLNYQKPEPLSPGVACTINAFVGQFSVQAVDFNILIMSVMVLLMLRTRKLSTEPSRPTILLICALAWVPSVITSSTGLALDAYGPVSGNWCWIKPQEASLRYALTHSWRMAIFLATLVIYTYIYIHLKRTFNSFVLSTSNITTHSLAPIVPAGGKANDNPDTTETSDIIVKRTFHVDGGVSWPDPTAPGVFASATSGSAIPLHDLPPAKMSHGAAATARMSRIDHDRHVHGGARHASNSNLRRMLLLNGYPVLYIVLWIPGIATRLVEAVRGSSPVWLVVMQASTQYVGLANAITYSWNEKMTERIKRLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGL3</accession>
    <name>A0ABR1VGL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alpha-L-arabinofuranosidase</fullName>
            <ecNumber evidence="7">3.2.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_010578</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.</text>
            <dbReference type="EC" id="3.2.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664183.1">
        <property type="nucleotide sequence ID" value="XM_066814893.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047953"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23399">
        <property type="entry name" value="beta-trefoil_ABD_ABFB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015289">
        <property type="entry name" value="A-L-arabinofuranosidase_B_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038964">
        <property type="entry name" value="ABFB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007934">
        <property type="entry name" value="AbfB_ABD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036195">
        <property type="entry name" value="AbfB_ABD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39447">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39447:SF2">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05270">
        <property type="entry name" value="AbfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09206">
        <property type="entry name" value="ArabFuran-catal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110221">
        <property type="entry name" value="AbfB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044964330" description="Alpha-L-arabinofuranosidase" evidence="7">
        <location>
            <begin position="32"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-arabinofuranosidase B catalytic" evidence="9">
        <location>
            <begin position="33"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-arabinofuranosidase B arabinose-binding" evidence="8">
        <location>
            <begin position="365"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8070375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="515" mass="52692" checksum="A571ABF1F127E44A" modified="2025-10-08" version="1">MVSKPSSRCGSSRALAFSLIAAAGSPLLVAAAPCDIYASGGTPCVAAHSTTRALYSAFSGALYQVKRGSDGATTDIKPLAAGSVANGPAQDTFCAGTTCLISVIYDQSGRGNHLTQAPPGGFQGPEANGYDNLASGIGAPVTLDGQKAYGVFVSPGTGYRNNNAKGIAVRDEAEGMYAVLDGTHYNDGCCFDYGNAETSGRDTGNGHMETIYFGDNTVWGSGAGAGPWIMADLENGLFSGPNVKNNAGDPSISHRFLTAVVKGGPNKWAIRGANAASGGLSTYYSGARPNAAGYNPMSKEGAIVLGIGGDNSVGAQGTFYEGVMTTGYPSDATENAVQADVVAAKYAIAPLTSGPALSVGSSVSLRATTSGYTTRYLAHTGATVNTQVVSSSSATALKQQASWTVRTGLATASGGQCFSFEARDAPGSYLRHYNFELRVANSDGSKQFREDATFCTQAGLSGSGTVSVRAWGFPTRYFRHYNNGGYAASNGGVHTFDAAGSFNDDVSWAVATGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHC8</accession>
    <name>A0ABR1VHC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Non-specific serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010825</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664430.1">
        <property type="nucleotide sequence ID" value="XM_066815140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048200"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8070622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="374" mass="41490" checksum="474E7045761DAA6B" modified="2025-10-08" version="1">MDNKVVLPVALDLRNSFPSSSNNRYVALKILVGASKPAKELQILRHLAQVTPSQTTHCTAQLLDEFEHVGPNGTHICLVFEPMGPSVNSMVEELPQFKPRRSILKQALQGLAVLHENGIAHGDFQPGNMLFALDDIHSKPEDVLRQDEDAQPGPVSAQVQRLDGKLDKWAPQKLYVAQPLAPFTRITEDFQIKLSDMGGAFFFTDPPTKPIVPLGLRAPELVLAGEVNKTIDVWSFGCLVFELMTGQPLFCVPWNDSETEQDDDHLLSLTTCLGPLPEALYRKWKTASLYFTPDRQIFNFQLGGVPEGGEPLMLEQVSMEEMFDRAKPDVDAEEAVKVNKLVRRILQYDPAQRPSPAEILRDPWVCDASGGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHF9</accession>
    <name>A0ABR1VHF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664467.1">
        <property type="nucleotide sequence ID" value="XM_066815177.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048237"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="374" mass="42243" checksum="8D3B31BE18C8F9DF" modified="2025-10-08" version="1">MGQKFRFAAPRAKRTLPWHVVGELGDVLFDDLPKVLVDLLAIPVKPKNTSPVLETCTIVAQPRAANHANNIPLEDTSKNSAETFAKHEVDPVRASRHGKRVKAKSDETSSDTKQPITFSNLPEDVHWLIFDQVDAVEDAVCLGLTNRYFWALGRIHLHNHYSSLRGRWAGQRIVCVGEDVDVGDYPPTLFSVEEVNQLLSLQVTEYSDEGSRKVPFTLFHFTEPPTSEEEIVCLENESRQIYDHSRYRGRNFQYEDISLEGIEGWLAKAEKILVNNETYFPADQAWILRNLTTKEFVRSEAIALRPEFIHGPNIDIIGFGEVVVSRICWSTSDSVNMKNTTNITRGVWAGHAFDITTLARHEDETKVTEAWGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIL5</accession>
    <name>A0ABR1VIL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011283</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664888.1">
        <property type="nucleotide sequence ID" value="XM_066815598.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048658"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF12">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="537"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="64"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8071080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="583" mass="61592" checksum="7188245EA9870558" modified="2025-10-08" version="1">MSSDTQKTAAGPPVNHASVASSDTSTEVQKKDVRGGDAGAQSDKEGSIRPHPRDSIPNWKWKAIVIGGTVQAIVNGYDVSNVANVQVPIYEAFGHIELLPWISLAFSLVNVASIPLFRKLTSFVELKIVSGIAVLILMVGSALCGAAPNINVVIVGRAFIGIGAAGCYQMLLTYNVIFAYPHEIALTQALIGACFAIGLLTGPIIGGAFAENEHATWRWVSFLLRLASGGIIAAACLGLYPSYKVPTNKPLTKHLKEFDYVGCTLHMGTFVLLGLACIFSGPTWEWDSGASIAVWVLFGLTLLAYVLQQSFCIFTTPENRIFPVSLLAHRAVALTAVGTSCAAVGYGATLYYTPIYFAFTRGTGALSSAVRLLPFTGVFVFMMFLVGGLLPRVRYYMPFYLGGAILMLVGAGCQQTITTQSPEGYVMGLEALVGAGIGMIWQVGVPVSSVVLPPHQRLDAAAVFNMAQLGGVAISLSIAGSIYQNVGFDLVRDAIGGLSGDYSDADIRLLLGGARSSILSAGHPEVVPRAIEAITTTILRCFYLSVAAGALCFIAACCMKLEALEFKKPAAAPAQLGEKTESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIY5</accession>
    <name>A0ABR1VIY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Forkhead associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665011.1">
        <property type="nucleotide sequence ID" value="XM_066815721.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048781"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051176">
        <property type="entry name" value="Cent_Immune-Sig_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 170 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715:SF37">
        <property type="entry name" value="LD47843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="34"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="735"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="791"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="860" mass="92857" checksum="B696D7046C158EC5" modified="2025-10-08" version="1">MASDSDSQSVADDARGLHSSIPARRIALRHNIPERIGRASKVATKGFVATPDNAWFDSPVMSRTHAELIAHLDTKTLFIKDIGSLHGTFVAKKDTPTLEKRLTEHDSAELVSGDKIRFGIEILRGRDTFPPCEVDVTMEWPNSDVSLPERAPSTNHFTVPDAEDDDMLSDGGSVMVMDREDFTLPDISQPDQSTVVDLTQEADPNTSGRTRHGLTSEGLFTTESSSDVIDLTSEIDEDDRSSSPIHGYSPEPSTWPNQPTSPAMSGRDHQDTQETHDLGHAQDSNVSVTASKNQSSETPAGSGEPHNPPAVISDLVAQHTYTLQDFGGSMPLPTYLESSEDDDDEDDSMSDVLEQRESDIGSEEGDMESQWSSDDNEELDEHTNSDDSEGEDASDPDEPCNEDILSSSDDESDVIETSIFDKTSTSTQSPKSSPVAVSTKPAPKLNPLYPVRSFNALCNLGVTGEPMQATAPPNVLTNLVAIARQPSPSDAAMVKKPAASGTKQEGGKTTAQVLGEKTGKFEYFAARDQNRETVQATPSQLVAPTQYMADHVMQNTNQEGNALKSSFKVDGYSSIRGSSPPSEHVNNTQGRYHQDSDAASKAPWRSLSFLQHPIEPPVKRSRPRSKTIVSGLPPKSRAAQRPRSLSQYYAPPIWATSSSSHGHISPDPEKRTRLQSPEHDMTSAFTFERSKAAAAAKSSNEIKVIRHARRMTIPDLLAEDLEKASSPLYSPPSPVEVSPEPVTAPSMPATSRATKRTYDEVFTLDDSEDDDSESNSVDSKSPRLGFAPDTPSLSRLSATKDASTSAPALKPSVALQETNGTQVQVAARSAEAPPAKRRRLADFAACALGGAIGGQLFLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJW1</accession>
    <name>A0ABR1VJW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010784</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664389.1">
        <property type="nucleotide sequence ID" value="XM_066815099.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048159"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="3">
        <location>
            <begin position="32"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="325" mass="35165" checksum="37995B1F79C6A51A" modified="2025-10-08" version="1">MQPPYPSLTPTWHNDVYPAIDYTNEKVSHKGETVVITGAGGGLGRETALAYAKAGAKTLVLTGRNAQKLIETGTQVANVNNDVQVKTVQAWVSDETAVQQIALTLGNATWNVLVHCAGHINAPAPIAQTEDVMDYWRAYEVNVKSLVVLAKVLFPKAAKDASVVTVPAGAMAFPVAATAGLSGYLVSKLALVKTVEYLAVENPNLNVTAVHPGMVDTPVFRKSGATPDSPMVHMDTRGCPLSSFCLRAFGLFGTWRLKRVTADDILRTTAKLFAGFCLWVSRPEAKFLSGRMVWANWDVDELKGKEEEITSRDILKYAWGGFPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU45</accession>
    <name>A0ABR1VU45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665716.1">
        <property type="nucleotide sequence ID" value="XM_066813754.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046814"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="160" mass="17744" checksum="7E3DFEBE3CACB2DD" modified="2025-10-08" version="1" fragment="single">MVTNRELDSTTTITTYYSTIVYPHHPRRLDSHDCSYTGIEYWDHRYPPKTAPNHETNDHRNQAWIAGPVLGSLAGAALLLTTAILLSRRRRKANGRHDGGNDAADKPQLHSDCIPTPLPTELDDSETRPPVELPETRVTGGHHELPDLRNPLSADVAGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV01</accession>
    <name>A0ABR1VV01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665572.1">
        <property type="nucleotide sequence ID" value="XM_066813610.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046670"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="39608" checksum="F2CB6643746DE178" modified="2025-10-08" version="1">MSDPAYNFMGLNNGISYCDGLPSSSDVMSSSHVSPTATHNSSFSSSHGTAGSDVFGSMNVEPMPSASYIVSTPPMQTHAKTIPSPFDYSSCQSVYDAAIANPQMGYVSPKDLRKHPSPSLIPTTAFNSSTESLPVQNCPFKAEPESRNILPSMPLRLTAKAKGRKELPMPVKLRPSPSRLPTPFSRSTVSPSSPSSSASSNAPGSLASPTVKTSLKTGLAHRSKLPKDKQPEAEESDSEVIRANAERAKKDEFLVQSKRAGMTYREIRRKGNFTEAESTLRGRYRTLTKDKNARVRKPEFLDNDVLLLKKAVHELAKGDSPTKARIPWKQVADFITNNGGSYHFGNATCRKKWDELVARGEADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVG0</accession>
    <name>A0ABR1VVG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666152.1">
        <property type="nucleotide sequence ID" value="XM_066814190.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047250"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="34823" checksum="B617420AC40448FF" modified="2025-10-08" version="1">MRRGPPPTGSAKPPLSFSNVIHPLPVIEEDAASHDDDETPKVPEKSPRRVSPLAATTAAAATRTRGSESAPRVTTPSPTPPPPPTRSILPLRRAAAAPSGSGGGRPTTAEQEASEKVERSLKSCLAKRGGWYRIALMAVLAVCAVVALTVGLTIGLRQKKGAAPVLFPAGSYAFTTALYNTTSGCTTNNSTFRCYPFQTYRQSKSEAAATYFWTIAPVNSWAFRISAAPNPFVPQFANLSLTQLDANQFSERLTFNFSMHGAAVVPTTALGDGKNDDENRAATCYYHDTLVTGTIWTRRPAEFPANLTTPVSNGEEQEEEEAAAGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW23</accession>
    <name>A0ABR1VW23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666390.1">
        <property type="nucleotide sequence ID" value="XM_066814428.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047488"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="589"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="841" mass="94500" checksum="3BECF4EAC22C9C68" modified="2025-10-08" version="1">MDDASDTDSVVSYEEINPRPKSQAQEGIGAFKLKEERNIEKLRSLVLKDGEASTELAEGDVPDICYVLQYKGIGGRVLPQLIPDRSTFGGGESPKQVSEKSKPILEIITKVSTTVTRNGGGGGYYPPPDHPPRRSMYDRGDPYSEYYGPHTAQYGDDDNLELKIASIEQTSMVIHSPYLINALKAVVEYYPGNSGFLGDTVTINAPYRLVYHHLTALRHYRDHQPATHDEEYASLTKRHINVLVDYINETLGARIEAEHQRHASSPPKALYENLWMLYKPGEVVYARHENSSNDWAPFVVSRCDSGKDDYIRVDCWNLTFSNGEFIRTTDEFEIDQFTDEAAISSLSVIPARFFRGEDGDEDPEDVEDRNVQLGRLTWELAKGPAYMTYDGNLVDASSNYDYGRPSNVNAAGYMSGRVVVDCDGYNRYGNGAGGPPSPGLPPVRMPRPPRHGYHPQQAINQRHPPRGRDPLPSFAACCGCAACKKEDDGRPSIFGREFESAKPVSDDAPTSDLYYLVLTKTVTGFILGERRWGHFNVRYLQDIRYDKEAFKHLVLDEDIKLTIKALIGKFASDGQVTPWPKDFVKNKGQGRIFLLHGSPGVGKTATCESIAELAHRPLLSLTSGDLSTNSLTVEKSLEYFLQLGERYGAMVLLDEADVYLEARRARDLARNGLVSIFLRALEYYRGVLFLTTNRVRAFDAAFTSRIHVALHYRSLTDADRQKVWVNSFERLERDSGGRVHVSVMAREYAYEAQEVLALAWNGREIRNAIQTAVALAETETLEEEDGNGAGRVEVTEKHLRAVVKMSRGFKNFLRRRQIQDDDVEQDDDSFDDPGCYDQIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWF1</accession>
    <name>A0ABR1VWF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666506.1">
        <property type="nucleotide sequence ID" value="XM_066814544.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047604"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="246" mass="25947" checksum="F79512C930C83FDB" modified="2025-10-08" version="1">MAYNPAAPAAPEQIRHREKTPPPPEDDGLDPLHAAVARDHQPQSVPYTPGFSGGGPMSPTYSIGVGGPMSPGFGGHHPTATGPMTPGFPPTATGPISPGFPPAPSGAPASRPRIRPRLAGPPEPEPLRRVPGLSQLRASPAPFVLGPSRLDEHARESVVAAAPAGRVRQLQLHAHEPALGGGGATDYSIHSQVYRPTEQEAIHHKHDSSGSYRPRSGEERSKLGQNADRLERGVTGMFKKLEKKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWQ9</accession>
    <name>A0ABR1VWQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666609.1">
        <property type="nucleotide sequence ID" value="XM_066814647.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047707"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="55"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="273" mass="30684" checksum="486800C94B96B2BF" modified="2025-10-08" version="1">MESNPEVIQDGCVTAIGQSPQAIPAFLIHDGGGTTFSYHCLEPLGRFTYGIFNPYFGSGERFEGGIRGMARLYADIIRRTCLEAEFPAKRNPDGTANVLVGGWSMGGLLSLEVAKVLTGDSDVRVVGVLMVDSMYTVDPPSVRLESWDSLDLGHSKNEFLSLQAMKEAVRVIHEWKPPVWSGQQAELRPRISLVRALDAIPTSNSDRIHFADVYRHDRALGWDRYEKDMFAEVLEVRGDHFEMFNFKNIPEVSTAIQRCFDRLEVMDDYQGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWW4</accession>
    <name>A0ABR1VWW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kelch domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666662.1">
        <property type="nucleotide sequence ID" value="XM_066814700.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047760"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF2">
        <property type="entry name" value="NEGATIVE REGULATOR OF SPORULATION MDS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="184"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="809"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="970"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1073"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="809"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="981"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1020"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1073"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1102" mass="117263" checksum="FDF7D6A04E81A037" modified="2025-10-08" version="1">MSGKKGLTSGFASGGVVDDEVCPWEFEPSIPASESEPGSANPARPSAPTRSPSDIFGEALRGIRKKANPSKEALAREKEEPRRESKDESARLNRAPSRLALKAFNNPNTPPPTSAPLPPRSGTPQHARKLSLQNSLEKPLPEPPPGLDTNSPTTPLASTQNNPSTNLDAIVDSDFEGDIQVVLGSDVESRSRTSTMDSNTSNPMGQMYGGNNGRMDTSGSVSSVASITRNDDHEGGQSRDTMAQRSNGPASAGPSPPAASSSRTPAVGQAVGTPSTSSSSTHLSGLMCNVHRTTGREPHPLVGATTTILGDKLYVFGGRILSRSRPAPLTADLFELDLIRRHWTKLETNGDVPPPRYFHSMCALGDTKLVCYGGMSPVNNQPAVTSQDQQPEVTVMSDIYIYDAPTKKWTYIPTQDAPQGRYAHCACILPSSAIFSSHKAPLSALQHNPSSGNPNEGRIGINIDGAGGAEMIVVGGQDGANHYIEQISVFNLRSLKWTSTQPLGKSCGAYRSVVAPLPPSVTSRLGKASAITPRQESGISQEAREPGSSMLIYSNYNFLDVKLELQIRGSDGSLAERPMSGAYSPPGLRFPNGGVIDHYFVVSGTYLTSSKQEYALWALDLKNLTWARIDAGGSIFSQGSWNRGVLWNRRNTFVILGNRKRSLVDDYNHRRINFSNVCMVELEAFGFYDSPRKVSPMSGFVSASSPYMMPGLSLARKAGWTAGGRFHSRAAEELGEKALGLRELSDMDILCIGGERIPINSRIVGRRWGPYFVQLLREGAATQDGSDSATLRTGLSSSAGARMSVMTITQSNTQSNRSTADSSLSGSFGNQSTNGSAKPPSTAATSVSGNGLTDFTTINAAPTPASLPPASRPRCLYLPHTYLTIQALLHFLYTSSLPATSSPLCTPQILCSLLQIARPYKIDGLLEAVVERLHALLDSRNAAAVFNATAMAAGGGRGIDGTLNPNFFVHPDSTLAGNEPNGRSMSVSTSGTGDDMSSNMSGLRINTSIPGARPGSGEHSATTSVSGSEWSSEVGDSERGAVREVWSGELSSVIGLQKRGLRGLMEGRRMRATVDRKRENDGSRVESYGQGPQRVGLGIAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX13</accession>
    <name>A0ABR1VX13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666735.1">
        <property type="nucleotide sequence ID" value="XM_066814773.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047833"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="23545" checksum="7D2699D624048A0C" modified="2025-10-08" version="1">MMFAVFFTFWRFMQILTLIPTMGMLAYFVHGYVTVNALTPDYILILFIVSVLALAWAIFTLFSYHRSSTNALFVSIIDLGFVGAFIAAVYYLAWIAKADCTHITRGDSYDVSFGIFGSANVNGVHSTTDKTCAMLKACWAFGIMNCIFFFFTAVLAWFHGDRGSSGHGSRRGKTYVRETHYHRHGHRHSRSPHSRRTSSHSHRRVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXU4</accession>
    <name>A0ABR1VXU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665583.1">
        <property type="nucleotide sequence ID" value="XM_066813621.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046681"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="30"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="24960" checksum="1B443DA20CDFEBDF" modified="2025-10-08" version="1">MQLTIISRSDISKPDFSRYDKELLETGNFSDVKLECGDRTWNLHKSIICSRCVWFQKALTGSYKEAQTNIVTLTTFSTEQVEMLICYIYTGTLNISSETATHDLLKLLVDFVVVADYFLLDAECHAAVLERLRSCLNRGGTRRRWPEFIETVEYAYGLQLADSETPRLMEARKVLVGWYNEKYETARKKIGPGAFSFLSQVPQFALDVLLARDRDGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYE6</accession>
    <name>A0ABR1VYE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665884.1">
        <property type="nucleotide sequence ID" value="XM_066813922.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046982"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034772">
        <property type="entry name" value="CPSF6/7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23204">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="383" mass="39837" checksum="8AD4CCE985C82B1B" modified="2025-10-08" version="1">MAEEEFEIDIYGDGSADQQHGGHDSSAQDANAQAYESNASVTVANGSNTAHAQNNGQDDYHGEGEAHNGMDTYDEAGAQTQHHQGVKRKEGSDDRPIDPGATNALLISELQWWTTDDDIRGLVKKAGVEAELKDITFSEHKVNGKSKGQVYLDFTSQQAATAGKHEFDEWSVAPGNRKPSVIYHGPSNPFRTLPKDAPTRGHKDQAGRGGSTAGGFNNHNSNNMGGNFGGGGGFRGRGGFNGPRGGYNRNFSGGNMGMGFNNNHMNGGGFNNGGMGGGFNFRGGGMMGGMRGGPGMNRGGRGGMNNSMMGMGNMGGMPMGGMPGAMPGGMPGAMGGMGMMGGGMQGFQGMQPQFNPGFFGGANQSGGNEWQQNPHGAKRPRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYM4</accession>
    <name>A0ABR1VYM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666381.1">
        <property type="nucleotide sequence ID" value="XM_066814419.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047479"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045908914" evidence="2">
        <location>
            <begin position="17"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="272" mass="27628" checksum="0DCFF60A6E427C38" modified="2025-10-08" version="1">MALVGLSLVLASVVWPLGLLLRLPRPPPQIDQPSPRDEDHAPRGAGQEKEGGEDVKSPVTITTTSADDETATPPGSSAGATTRKAVNPTPAPPTVEEPSSSQTTPKAAPSQRTPNGSVPSFSLSPTPSSNSSAPKLVAPPASAAAVARSNAASMPPPAPPTFSAPVIPDPSFSSPATSASSMMPPPPRPPTLNNLNPAATSRAANLSAPNSFARSARQPGTSTLAPPPTHSSKPAKPSRKVMLEPGHSPLDWARLAQSPTSDLRNLPAGTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W082</accession>
    <name>A0ABR1W082_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666529.1">
        <property type="nucleotide sequence ID" value="XM_066814567.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047627"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="118" mass="13563" checksum="223DC814F24BF4F2" modified="2025-10-08" version="1">MADNIPRAQTSGQLQFRAMRLYERRKRARRILNAILAASAAFTSLPDEKQDMIRQECEIVIRDNINEFMDNTPPRTVYPYEEAVLAAVKSVVYWNPDVLVYNEDDWIIPAEDAGGDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7L6</accession>
    <name>A0ABR1W7L6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666947.1">
        <property type="nucleotide sequence ID" value="XM_066811605.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044665"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="58"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="397" mass="45086" checksum="BF96723757AD4707" modified="2025-10-08" version="1">MGFRSFFGLTKKKKEKRKKRRGGRSSSDDDEEWRRQDPYMPSVVRAHLTKHFRDRGDYRFSRLLGVGGYGMIALLENPNKNPPTRLVLKRALRRDMVDEIRDEITSLKRFRGAAHIVQMVSFRDRDADETSSDGTLPGPYIVLDYLENGTFQEFLERVVKAKARPPNRVLWSILLCFIRACVGLTWPSRGFQGQRERLEETSAVRGPTAAIAHSDLHMKNVMFGSLQPDVEEHSLVPLCKIIDFGAAQSTELYPTAGVAPNIWQGQPSNTESLARCFSLLPPLGQQMLLRLIVGTTVLPPKTRAVMSNGVETDAAPLWARGEYQRYPWLDERLRVIVGSLMTPDHRYRPTLENLLQGTTQVLSGLSSRSFPQAMQQNETTRAVRAFVQRFLLDAQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7Y4</accession>
    <name>A0ABR1W7Y4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_007402</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667059.1">
        <property type="nucleotide sequence ID" value="XM_066811717.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044777"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF20">
        <property type="entry name" value="[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase N-terminal" evidence="9">
        <location>
            <begin position="26"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8079584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="361" mass="39494" checksum="8B5C31C6CFADC23D" modified="2025-10-08" version="1">MVASPSTAAVTDDEIVDLSNKHQHSLSLADLVKHGRPPLSSEALYQSANFTLSLLPIRLARRIQALRNLPFIVVSNPNISKIYNNYLHSLSTLLPWKHRTIGNLDAEIRFTSVLAELVATHQDTIPILAKGFLECRRYISPSEQHIALHYSSAPHFDPASSPTPCPEHPSYIGVIDTALCPAQVVDSCANWVAELCELKYGVRPRWIIDGEPDTQFAYVPMHLEYIITELLKNAFRATVENRRNREPVVITVAPEPPDAGPPRVTLRPPAEDMGAFRSEDIKPLDDNAPGVTIRIRDRGGGISPDVLPNVWSYSFTTFSDYEVPGGSEGGGGGMMGSDALNLISGPMAEAARSPAWGTACR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W820</accession>
    <name>A0ABR1W820_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">G protein-coupled receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007449</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667106.1">
        <property type="nucleotide sequence ID" value="XM_066811764.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044824"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023041">
        <property type="entry name" value="Glucose_rcpt_Git3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022596">
        <property type="entry name" value="GPR1/2/3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF37">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR GPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11710">
        <property type="entry name" value="Git3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11970">
        <property type="entry name" value="GPR_Gpa2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose receptor Git3-like N-terminal" evidence="7">
        <location>
            <begin position="45"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="G protein-coupled receptor GPR1/2/3 C-terminal" evidence="8">
        <location>
            <begin position="422"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="241"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="548"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8079631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="599" mass="67105" checksum="FA2D59BF8AD8DF33" modified="2025-10-08" version="1">MAHQPNPAFAKLVIPRIANGTDDGVDKNPDGLPVSFTPHTLYILESVSLSLSTISVFAALVAFYWFVRMRRSFRQDLIMLLIQSDMMKAFWLMLCPIVYFIQGTPVDTSDTLCQVSAFFLTSAIEASDIAVLMVAIHSALFILRPQRSGGENGLYPYRRYAYAAWFVIPLILAAIVPITGQRYVNTGPHCYLPVQPLWYRMALSWVPRYIIFAVIICTYSGLYLFLGFRFYRLQLDQRRASTNTGPSGFRGHVKCMSRSREPPPTPTLASHGLLGPSPPRTAVDRAPDHERQQSITSTSAAHDAAAKSQSEPVPWNWVESDFQAQSHPETRQFGLDSASPTAVSFALDASGITPPEPVLRDAPKEEGLEMAHPNLPWQQQSGGADRSARNPLLAAARWWILHTTIYPARKSRLSVTEDALYQSRMKMRKQLRLLFVYPLMYIITWIAPFVSHIYTTADPDHQEQPFGLLLTSVASLCIGAAVDCCFFSSWEQPWLHLQGGFIEGFARRVSFGTHKKTMGRTREEQLRDASAALDRRNQENAEREAAAALHRNGRHRVPGSGGTPSRKRKSAPHKEGGGIHIRGQGAYSYWDLNFAFDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W826</accession>
    <name>A0ABR1W826_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007447</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667104.1">
        <property type="nucleotide sequence ID" value="XM_066811762.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044822"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="3">
        <location>
            <begin position="45"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="336"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="344"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="48654" checksum="4CFAD6D97500511F" modified="2025-10-08" version="1">MAPAATSVADDGGIEPRGPDPGRIITKHDFICEQHIQMLTKGVSKEEQYRLEGVALIESVRENLGLPAKTFATACTFWHKFRLHYGRTEFPFNEAALTCLWFACKTEDTQKKSKEVVCASWNISNPSDQRTPDDKVFEKRSQSMIGIERMLIETLAFNLNARYPLGMMVKLIKKFLAREEWSTEFYTIAWDMAFDIYKTFAPLKKTTWTVALSLLELTSRLTGLYQDKILSINCEEYGVSRAHMLEVMSDLLDLYTQSHKHTRLGSQYPLDRFIDIKITINKEIEDRHIDFTSWCQDCAFHAPKPPFPPASGAGIGNTEAITKRFIFDRDAAREEQDITRPYFEDDFEEYETEVEEEVRPEPDRSRDRRGPEPKRPLGPSHGRHGGRRGGGGGGGGFGPGGHGGPGRQGDGWHGGRRREGRRGGGGGGNFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8Q7</accession>
    <name>A0ABR1W8Q7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Membrane protein TMS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007687</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TDE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667344.1">
        <property type="nucleotide sequence ID" value="XM_066812002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045062"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005016">
        <property type="entry name" value="TDE1/TMS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383">
        <property type="entry name" value="SERINE INCORPORATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383:SF9">
        <property type="entry name" value="SERINE INCORPORATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03348">
        <property type="entry name" value="Serinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046853144" evidence="8">
        <location>
            <begin position="23"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8079869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="478" mass="52266" checksum="17812E2223B96841" modified="2025-10-08" version="1">MGALLSLPLLAVPSMGTLVSFAASCCGAATCSMVCSACGKCGNSVATRIAYALMLLVNSTVAWVMLTPWAVEKLQNLMLDYVKINCPNGECYGRLAVQRINFALGLFHLIFAGLLFGVNNTKNPRAALQNGFWGPKVIAWVAFIVLSFLIPDEFYVFWGTYIGFIGAMLFLILGLVLLVDLAHTWAEYCLEQIENTDSKVWRIVLIGSTLSMYLGSLAMTIVQYIFFASSGCSMNQAAITINLIMWLGISFVSVHPAIQEHNPKAGLAQAAMVAIYCTYLTMSAVSMEPDDKQCNPLIRAQGARASSVVIGAIVTMLTVAYTTTRAATQSLGLGNNRGGIRLPDDDEHGLVTQQPGRQDMRREVLRRAVEEGSLPADALLSDDEDDESSGKSSNDDERASTQYNYSVFHVIFFLATCWVATLLTSTWGDEEVQSGDFAPVGRTYWASWVKIVCAWICYALYTWTLVAPIVLPERFELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8U9</accession>
    <name>A0ABR1W8U9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Carbon repressor protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_007660</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the creA/MIG C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667317.1">
        <property type="nucleotide sequence ID" value="XM_066811975.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045035"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051007">
        <property type="entry name" value="creA/MIG_C2H2-ZnF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428">
        <property type="entry name" value="REGULATORY PROTEIN MIG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428:SF1">
        <property type="entry name" value="REGULATORY PROTEIN MIG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="112"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="260"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8079842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="407" mass="44747" checksum="AB13EEAC5A1F706A" modified="2025-10-08" version="1">MQRSQSAVDFSNLLNPESASSAVHHNDQLKLDQDGDVDMATVSVIRPNGPLPGAAGAQPADNNHSELPRPYKCPLCDKAFHRLEHQTRHIRTHTGEKPHACQFPGCSKKFSRSDELTRHSRIHNNPNSRRGNKNTQPTHHIMGNGLSDHMMPPRLGRDRSSRHPTPPWSRRIRGIGGGSPLNGHSNDMLSNAASQVEREYTSVPHHHSVRHHPYYSHSQHSSRGHLPSLSAYHMSRSHSNDEHHDDHYSQSARHAKRSRPNSPNSTAPSSPTFSHDSLSPTPDHTPLATPAHSPRLRPYANIELPGLRNLTLGHTPALAPMEPQNFDVNNNNTYQQAQPQGTPTNTTRSHGLSLTDIISRPDGSRKLPVPQVPKVAVHDLLAPNDGFNSSGRSSASGSLAGDLGDRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9L0</accession>
    <name>A0ABR1W9L0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008003</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667660.1">
        <property type="nucleotide sequence ID" value="XM_066812318.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045378"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF160">
        <property type="entry name" value="SAT4 FAMILY MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="30"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="385" mass="41951" checksum="E8E5CA7408654729" modified="2025-10-08" version="1">MCHEPIRDESLNQTLIAIVGCGVTLVIFLARIIFQLFHNGWNLAGEDYSIIAAMALTVSISCISPFADLNGVGRDIWTLTPENIESAFYYFFVAEPIYFVAQGLVKISILLFMLRIFPKRNMRTLIYGVCGVIVAYTVAFFFATLFQCQPISFFWKQLDATFPGKCNDIHLQAWIAAGINIALDIVVIVLPIKSLWNLQASLPKKITAISMFSLGALVTVISIVRLQSLIMFSKSVNFTWDGRKAGSWSLIELYVAIVCTCLPAFRIMVMALGARFFGWNNSMTTRYGNGSSGYGQGYGTSSKLARSHKSLAKSASTTTMLNPAASGDFIRLNDIEAGNSGNGNGKPLGDGESEKTLVGSGGGCNGGQIHVTRQVVVSSCEPPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9M6</accession>
    <name>A0ABR1W9M6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667675.1">
        <property type="nucleotide sequence ID" value="XM_066812333.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045393"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="1">
        <location>
            <begin position="26"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="31854" checksum="6F511B8B9380C93B" modified="2025-10-08" version="1">MTPDKILGYSLLWYDGFRTTEEAPYHKWNSIVNQTKYNNEQQRYDSAWDVTHIHSNFGGPEPHVGDTMYITPQLHDGEWRSARIEGKEAYSCPAGKSLILQANLTVGGAPSDRQAGIWPAFWALGDSQRHGTEWPMCGEWDIFETSDGHDWTLGSLHWGEKNPDGAVGRISLPTGSADEVISEYGNRYDHTQPHTWSIKVDRTKGSWKDETLTWSMDGKQFYQVKGSDVNNEEQWGVLAHEPYFPVLNVAVGGTFPKGGQPNGQTATGMDTGMTVQYVAFYISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAT9</accession>
    <name>A0ABR1WAT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pre-mRNA-splicing factor cef-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_008423</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CEF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668080.1">
        <property type="nucleotide sequence ID" value="XM_066812738.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045798"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11659">
        <property type="entry name" value="SANT_CDC5_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047242">
        <property type="entry name" value="CDC5L/Cef1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021786">
        <property type="entry name" value="Cdc5p/Cef1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047240">
        <property type="entry name" value="SANT_CDC5L_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885:SF1">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11831">
        <property type="entry name" value="Myb_Cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="11">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="53"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="11">
        <location>
            <begin position="57"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="109"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="238"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="402"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="736"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8080605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="777" mass="86537" checksum="8CB4D022C2E883DC" modified="2025-10-08" version="1">MPVVKGGVWTNAEDEILKASVSKYGLNQWARVSSLLQRKTAKQCKARWSEWLDPSIKKIEWSKEEDEKLLHLAKLMPTQWRTIAPLVGRTANQCLERYQKLLDEAEARESGSLGLTGPEGGETQAPTADDVRRLRPGEVDPNPESKPAKPDTIDLDEDEKEMLSEARARLANTQGKKAKRKERERQQEESRRVAALQKRRELKTAGINIKVITRKPGQMDYNADIPFEKAPSRGFYDTSEEQHLNERERALFNPQKQQLANKRKGEQDEEGERKKRKNDKEGPSASMQAALKAGQMQKIREAEQSSKRRALNLPAPQVGEGELEEIVKMGMMGERASSLAQSSENDATRGLVNTYSTITSQTPIRTPMAPAQEDHIANEIRNIKALTNNQSALLGGENADLEEGAGSTGFESATPRKQVMSTPNPLATPLRNGANGVGATPGRVGQTPLRTPRDSFALNAGNEMALVGGSARAREMAVKRQLKQGLASLPKPKESDWELEAPEDQMEVVVAEESVEDAAIRDRREREIREAQEALERKRRTQVLQKELPRPDSVDVDVLMKEATAIEDPVEALIAREAALLLANDAARYPIPGSRTKTSPVNLAQIDDNALAEARLQILLEVKDQPKREAVASVFERENANALMLGLGCYEEEEEAQTQMMKTAFDNVQITTMEIAEKCSKVEKKLGLHLGGYQNRAKVLRQKMGQAAEELEKAQFALNAFNTLNMSEEIAIKSRLEALREEVAYVSRREREAQEQYREAKEELDAVGGAHGVNGYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC15</accession>
    <name>A0ABR1WC15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667475.1">
        <property type="nucleotide sequence ID" value="XM_066812133.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045193"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848:SF1">
        <property type="entry name" value="SUN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="357" mass="39578" checksum="07F0C82B19A8A012" modified="2025-10-08" version="1">MENHDSAFTDKTGHAIRPVHRPSDHASGSNHVPLAELAGDEGDVNAPTSQPAKPPPYSTPSSTSLEVRNNQSVPGKGPQYYPGLPLLDYRQYAPPMFELSSDTTTIASKATYLSANAKVLSTLLQTLASVPPKPQILVQGTRGRRVDFSIKMNLMSLLVPSDPQDRLDYIRVVKRDEMAYRGGGSQPSLQPDVAGGSLQSWCERFVADPANIKTFLLERVVANLDTNWLEGQLRSLVAATDYNGHVTVSFPVTHCKVLVQSPDKVNKFFTSVSALFTGKSKYEVIKAVWPFASAKNNEQGRKCVVQSEKTWWEEWKDSIKYAIVTKRHGYVTNEDKLECIMESKGKSVTVNWEMAEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCF0</accession>
    <name>A0ABR1WCF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668573.1">
        <property type="nucleotide sequence ID" value="XM_066813231.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046291"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="237" mass="26281" checksum="3E52E7986777AB7F" modified="2025-10-08" version="1">MSFPWSEPDQRRLLLEGYPVICLGQLYLTVYRRLFDPTTGWGDMFANLGCMAVGHLVANANTWQPATLAELPTPPASYGIARQVCYYATRRRTRNYLITCAWSHALALSLRYLLPQVPKLLRLPAAVASGLPRLVATPPSHHWAGAVAGLSSYRRRLPGLALTVLGTAAGCWAVSTLGTFADVDTLRMIADPEEEERRARRASTPEWQKENTRMVQAVGIAMTGIGYGIRYMVMRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE38</accession>
    <name>A0ABR1WE38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668195.1">
        <property type="nucleotide sequence ID" value="XM_066812853.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045913"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="657" mass="72007" checksum="CF64F0219AE6AA51" modified="2025-10-08" version="1">MRERRQQDYLGPMLPEGVKYILNLTPPDMGDDLAALVTILSVPESVRSWWQSGLRLNVKRSLVSGHDDACSDHEHVPDDCEPLPGVSMMPTEGQPQPQSLLPALDLDDIVGPVVSRQIPDYCPIRHRANVIFIMEAILCGNTYSVLKALDSATRVYTVVKLAKVLDCVDVVLDPVYSWALAHPSGNFIELLPEVSLGLFWDLKIVDIVRSTFSILVVEGAIEFLGAPTDLSPNTAPTLNTSRTGPTTIFGRKRDAVPEDIFNALEHARDSLAERTHATLAHFKSDGIYDLLSRGDLAGKGIPEWDRLSNIGETLGCIVPGRFADAPVSPPVPVLTAISEHQQNCLLRLRLAYDRLASALVAYFHVSMAESFNGNDCDFSRADLDRKCYVPRSRFTQTSVIYQRLTEEQRALTVYPWYKMMTKANADTKDQFDSLPVYGSTIAQLSMDFNQHLLDGMLLFPELMSYHGLYLGGRITFFSLETFRVQYAEAMESLHQKRRLGSLDGVDFLTRSQHMALGAAEEELCFLPMWAGGNDDDLGGVYDSGFVPDTAHGPSGPGPAFHTGYSVATAASSIAPSTPTVGRTTDDDAVTVGRSIAAAVSFSSNSSTAAVNNHSLGHPSEETDRWNSDDFMLESAGSEDLDDFDLAESGSDDDFPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEM2</accession>
    <name>A0ABR1WEM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668390.1">
        <property type="nucleotide sequence ID" value="XM_066813048.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046108"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="95" mass="10197" checksum="D591CFFD86D0D380" modified="2025-10-08" version="1">MGDQSLAEGVDGTMEAKKKRSLDTYLLDTEQVDETPSKRPYHTGPDSLSSRVTDWLSQLPLESPPEADPDMFGALKKDKGKGKSKSDGSVVGGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WG81</accession>
    <name>A0ABR1WG81_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_008911</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668568.1">
        <property type="nucleotide sequence ID" value="XM_066813226.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046286"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="15">
        <location>
            <begin position="50"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="281"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="650"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8081093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="696" mass="77710" checksum="365BE55BF9FC0FA3" modified="2025-10-08" version="1">MDTTTTMIGPQPRGGVQSRASRLFGQSDGTAGGSIMRSVLLRHFDGGQVATALTTVDLAFNMYHYAADTLQAVWTWVIRHCVVTVEITYSSELKQSVLTYVGDRVLARRHPTELLAHVTQRRPGDLDFYYGSSGAVASSSSSSSSNRPRAVRFVPKFRSVWFFHKRCLLMVKSSSVTTCDENVNDYADIQEDLTIVCLGVSSEPIADFLDTCRALYDKKRETYITTFGNSGGHWSQKLSKVPRPLSSVHLVESVKEELVGDIRSYLDVRTQRRYHVRNIPYRRSYLFYGPPGTGKTTLSEAIAGVFQLNIYAIDLTSVLGDKDLARLFQGLPQRCIVLLEDIDVAGLVRDKDTKVIATSSILSTPPPPPPPPPPQPPFPSSSTNAVLAGAAMMSPDQTPLFAHPPIFNRPKPRATGCTLSGVLQALDGVGSQEGRIVIMTTNRPEDLDDALIRPGRVDKKIRLGRADRDCARDMFIRMFEPNIAATSSRYNSHHTTPDGAFNIQGEEILLLDHNAPPPTCCDLCPTLDLPQIRALADEFARQVPEDTFSPGKLQGFFQTHLECPRRALAQIARWVEQETRPQFEEETTLHICVRRNNSVIDGGLPEDTWWYRLKPRDALDALFQDLQRRVAIPEKAGLSQNRKMRLTHREARVHRSDTPESLKLKDNDKLELFLDPEKSNGHATEEEMRSLATKDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNI6</accession>
    <name>A0ABR1WNI6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dfp1/Him1- central region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006361</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669599.1">
        <property type="nucleotide sequence ID" value="XM_066810676.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043736"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00027">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3410">
        <property type="entry name" value="DBF zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055116">
        <property type="entry name" value="DBF4_BRCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013939">
        <property type="entry name" value="Regulatory_Dfp1/Him1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051590">
        <property type="entry name" value="Replication_Regulatory_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006572">
        <property type="entry name" value="Znf_DBF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038545">
        <property type="entry name" value="Znf_DBF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375">
        <property type="entry name" value="ACTIVATOR OF S-PHASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375:SF26">
        <property type="entry name" value="PROTEIN CHIFFON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22437">
        <property type="entry name" value="DBF4_BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08630">
        <property type="entry name" value="Dfp1_Him1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07535">
        <property type="entry name" value="zf-DBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00586">
        <property type="entry name" value="ZnF_DBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51265">
        <property type="entry name" value="ZF_DBF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DBF4-type" evidence="6">
        <location>
            <begin position="599"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="425"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="528"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="666" mass="75131" checksum="44219051E4AD62C9" modified="2025-10-08" version="1">MSGTARRIPLSNNQNVANSPIRSSAAAFAAAKQRRSYANMQREEAYGHPPPAKKQMLESGIPRPLNSPSKRMAKPQVPLQARRTTSTYENRLARERMGHHQTQHTESKSNRYTEKDLEEIRQWKEHHRARFPRMVFYFENIPTEVRAKLGKQIEKLGAREDKFFSNDITHVVTTRSIPPEKSARQREEEAANTTTEIHDGHEQVQTINPSLLNRVTDGTPSVRRKLFDTTSTAVPSRRPLTQLQDTRPKRNMDVLHRAREMGKKIWSMDKLQRMLSMLLEEDLLVSAAIAYGGSKSGSVRASHADSRSVHEPNLLQLLQNERVNGPSDRDPTVTTQELHYFKGPYVYVYDFEEKQKPIMVREYQKVADKADGDWPQFRTAPLGRCPFVEDYDHREVAKPKPKPKQVTAKPAVDAKAVVQTPEAPLAKPVTGKRSIGEMESAHNRGSSVTSVELTNSMKPGNKFEFRPNFTSRAGTTRLFGGEPVASGVQPSNVTSAIRSQMISSTAATPGAIGMMSKEVHGLQRKVLQRNSSHDLSSRRAGSVDPSLRDDPTARRALTLSRTSSRRLDLVDDATTCEDEDAKARAQAEKRAAVKAAKKRDPKPGYCENCQDKFEDFEDHIASRKHRKFADNPDNWTELDDLLSELQREPKHKSFTAWTPSLPAFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPE8</accession>
    <name>A0ABR1WPE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669902.1">
        <property type="nucleotide sequence ID" value="XM_066810979.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044039"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364343" evidence="2">
        <location>
            <begin position="23"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="234" mass="25754" checksum="6A5A508510D582F0" modified="2025-10-08" version="1">MVSARASAIGMAITLLWATANAAPTGVRSLDARNLGKIAERAEASLDSKPRAAEEGVDLWSDDADQAEEPETNDGLEKRAKGDKSDPYNMVVDVSQIQDMAELNCYVMLCDYGAKRQTTRINAGTTSAEEFPWASLMAGGAGAHLMSAEEDDQNIQKNMISAAFARGRVPFEKYARITFQGYDKSRTYCKALFSKPPDFSVCGNRSRFYGTLINPRDYDYVKVQNSNPIVFKHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS87</accession>
    <name>A0ABR1WS87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670193.1">
        <property type="nucleotide sequence ID" value="XM_066811270.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044330"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="204" mass="21621" checksum="B55D7C9D34D8657B" modified="2025-10-08" version="1">MSSDSASANKETTTPAANKENTTTTTTEDATPIQSAEVHTTITTTTTTSSNPHPPLLPSRPRRMTSSDCNNTVGNSDAAGSAVDATSGGATPPAKRHTADGKTYLSPSSFQAIKAETEDMLATQTQALRDLKDRLDQDMSKKQQQQLAVAVQEARALNDAYRNKDEDKDKKEQQQQLAVAVPDIGGKAAPGPNSGDKETTKSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX76</accession>
    <name>A0ABR1WX76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670655.1">
        <property type="nucleotide sequence ID" value="XM_066807037.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040097"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="42306" checksum="0AB4C23846AAE0DF" modified="2025-10-08" version="1">MASSGNSSGSGSNGQSQNPDAPFRAGDMPPELVELVFDHSGPVDGAAMAFACKDLKKIGNINFEDFWKDQDAAWEFLQRLEPEANPRLVPCRECLSLHSPQFCLPSFDGDGEDMNAYKCRSVRTVGPLGLGHPMRSPDFLLNIQPALYAMAKYIRLGLDTSFFAAAEKDREDRYRVRFSLSADDTTWGEVWEQVNVNQHGLFWRQQHVLELKAAYRPGPNDDNSELDYIHSWLNCYCHRLAPRLWVYSDPAGKPVCTVYGADKTNGRGRWFSSPQKFWRNTARMLPEDFHVQPSQQAPLKGTIIGCENCGTEMRAEVRFRPDNTPQLVLTTWEFRGEITTPDSLQANLNNILRCVTLHRLPGAVGKVAELSGMMQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXW4</accession>
    <name>A0ABR1WXW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">40S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002961</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670894.1">
        <property type="nucleotide sequence ID" value="XM_066807276.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040336"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_uS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003140">
        <property type="entry name" value="PRK04053.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="17891" checksum="575C8F304796EF8F" modified="2025-10-08" version="1">MSLVSGEKTNFQFILRLLNTNVKGEEKVMYALTRIKGVGRRYSNLVCKKADVDLNKRAGELTSEELERIVTIIQNPTQYKIPTWFLNRQRDIVDGKDSQVLANGVDSKLRDDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVGVSKKKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY90</accession>
    <name>A0ABR1WY90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671024.1">
        <property type="nucleotide sequence ID" value="XM_066807406.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040466"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057720">
        <property type="entry name" value="RRM_YTH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357:SF3">
        <property type="entry name" value="YTH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25701">
        <property type="entry name" value="RRM_YTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YTH" evidence="2">
        <location>
            <begin position="375"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="610" mass="66201" checksum="112765D902ADB6AB" modified="2025-10-08" version="1">MGDAPPNTSSPNDLTHPEALGGTFDDQGNSAGSHVGLSTFQPQQHFDPSHNAFSAQFDMTHPQVNGRLGPYNMGAMANALPQTNYRPTYTQGAQPRYNTGGPPPGVAHSMPQMAQYGGHTAVNPIVGQQYYMPHHPQVQQFYGHQLAPSQQATNMSPRHNLAYYPNQVMMNPAQQQLSGGYYYGQPGTYAGQNQAIPGQMMPGQFIASAPRGASPSGPQDQFGSMPVLGPADEASRNRSNVVRGPPRKPRQSGNAIWIGNLPPQTDLMSLVYHVCQEASGLESLFLISKSNCAFANFKDEQSCVTAQQKLHDSKFQSVRLVSRLRKSTVEGTAGQTAPTGPAATSPHVQVAPDEAVEDPPETNAESHTTPDKWPDEHREAPAGDVEDLELSVRNGVWATQSHNEEALNDAYKSVDNVYLVFSANKSGEYFGYAKMTSPINNDPAAAIEFAPKAQTATDSDLPKAIPTEATEHCPRGNIIDDSARGTIFWEIERDDADTPETESEVDDSASGQDGQDAEGGSKAWGKPFKLEWLSSSRLPFYRTRGLRNPWNSNREVKIARDGTELEPSVGRRLIGLFNRVQSPAPMAMGMRQGMAMVAGYPPPMRAPFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYB5</accession>
    <name>A0ABR1WYB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003043</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670976.1">
        <property type="nucleotide sequence ID" value="XM_066807358.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040418"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF10">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G06760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="54"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="524" mass="56935" checksum="728D9A52968A666A" modified="2025-10-08" version="1">MDKKTSKDDLFPAVTEKSNPQSSYNEHPGTTTDEEAQSIPSGQDGSPPLLQMRVSKTKGVGVITTLAGINFLNTMGSGILIAALPRIAKDVGLSTTVYALAAGCLLHVFGSFADILGPKRVWVVGSFLFVVFTVALGFSVTGIQVIMFRTCLGIAMAMCLPTSVSLITNTFPKGHWRNTAFAMSGMAQPLGYALGLVLGGIFTDTIGWRWAYWIMAMVNFVISVISVWSLPDVRHPSKKTWARRLREDVDWVGVLILSVALALLMYVLAMITSDWRNVKKPAQIVLLVVSILLLVAFPLWMRRQVQVGKPALIPNRLWRKASFTSACLCVFFCWSSLNGIEYFTTLGPGLIGSLQSSIRYFSQIVMGTSVNIVLVYIISRVKVITLVVVSTCITLISPALMATVGELENYWFRPFWALFLCPVNPWVLFSVSNLLISDAFPAEIQSLAGGVFNEVAQFGNAVGLAVTAAIAASVTEHSNAEGKTATMDGYRAAFWTIFASSATVLIISIVGMRRVGTIGKTEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYT7</accession>
    <name>A0ABR1WYT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003292</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671225.1">
        <property type="nucleotide sequence ID" value="XM_066807607.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040667"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057215">
        <property type="entry name" value="DUF7893"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF54">
        <property type="entry name" value="DNA METHYLTRANSFERASE DIM-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25423">
        <property type="entry name" value="DUF7893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BAH" evidence="8">
        <location>
            <begin position="571"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="481"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="903"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1238" mass="139626" checksum="7B1248994484531D" modified="2025-10-08" version="1">MPDQLDVLRPNDGAILNDDQWAAEVSKGMRLGFDELREIAPGEGTISDQDHDYSTWFNSTGISDLGFAPISPAPWPKSINDDDSDDVELQSCSDAATVQSEPYLGPTSSNLVVELPISTLSNPRSQYQGFVPPAPQKREWQAVEALLNVLAETGREPEPEYIEFELSDFSVYVNSSHYPLELRPLQHLCTRAASDTFYLDGVLSATNPISGTTMRFYVQRAPFRELPIEAYDDEAVTVESIWIRSDYNRKKEIYYKLGTPSREYERFHAPFLWVADLAHHVITYCAYLHSKGRKATLEDFQSRFKIFLCRKHNESVVFQSWAAAHGSDDFRTAVVANVDFLWKEAVGAGDERPGSPFHHFWKEIYGGFYKPNLSSAAQIRGDDDGDEDDQVDNSKNRTKPRVQDGKVAKTIVTPYMYEAFKDMPFGDVLAPISLATTVQACQTAMVQGTSQYWEDGKIDTLKGSIPVGNFDDEGLALSIRPGDVISTPPTEMKPIRNGKLKHRNTPSKNTSGKVEAKDVLAKHDIHWFGTPADSGLFVRQTYLADDKRWVSLERTHMFCAHNKEGNQPDLSLYHPGDTVLANIGLEYLQAFEVDETFKENKRRMVRLRRLLRRKEVDNTALDSPANELVYTDQLVETKLSAVVRRCLVRAFRYNEQLDRLDEKITAPYDRDGTGDAFFITHREVWDEHGGFHYMPLGDGDDLTLRQGFHPDHATKLPRLSGLDLFCGGGNFGRGLEDGDGIEMKWANDLNPTAIHTYMANSKPGCTPYLGSVDDLLHAALTGAKGAPRPGEVHFISGGSPCQGFSVLTNNTSTPRQRKNQSLIASFASFIDCYRPYYGLLENVASIVQPQSKKESCFFSQLVCAIVGLGYQVQILPLEAWSFGSSQSRIRLFLLFTAPGLRAPKPPLPSHSHPPGTKQRSFGKMSNGLPFGERYFGPTPFKFVSAHEAVYDLPGIFDGLADYCVGWPDHRTNGFTANLREQLKLIPTRPWGMNFRKLFYDEEGRRIREGRREMDRNLFDSKTGKSKQRTEPCSQGWGRVYPNHLFPTITTKCSLTDSKIGRINHWDETRPLSILEARRAQGFLDHEVVMGRPNTQWHIVGNSVDRHVALAFGLAIREAWLGTLWEDGREQQPPQQESSLVDHLRQRLSMEYDGLSTPDEIELVPCERRDQLLDPTTESSDEDKVFRDTPRGFYELTPATSIDGNEDVGAVSHERGQKRANPFLVEFMSKKFRESEDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYY0</accession>
    <name>A0ABR1WYY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671268.1">
        <property type="nucleotide sequence ID" value="XM_066807650.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040710"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="224" mass="26017" checksum="455E48A034E3CA4D" modified="2025-10-08" version="1">MKVIKNILGHCPELEQLRWDLNTQSWSEILPDDEHDSTCLGPGGQALKEFRLVNRDYDYELPQSFLEEEVLPMPLRCFQGLAKLEKLRVDLEGLARVTVTEVCLPASLKELEVVVACEGDFHRHWYQPDMDEYEDREEEKRFDWGEPRDTWLSLCFVKLDKAVSSGQLPNSRTLVVDHELDPESCELIAFDRWKAYYEHIAAILGKHNIMLSWTWSSEQGAPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZD6</accession>
    <name>A0ABR1WZD6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxidase</fullName>
            <ecNumber evidence="5">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003482</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671415.1">
        <property type="nucleotide sequence ID" value="XM_066807797.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040857"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF53">
        <property type="entry name" value="HEME PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 5 7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044966520" description="Peroxidase" evidence="5">
        <location>
            <begin position="25"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="6">
        <location>
            <begin position="121"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="516" mass="54396" checksum="8B60BF2F08C2A1DC" modified="2025-10-08" version="1">MSRLSQPNLLFLLLPALLASGGGAMFFYPDPQASLLEHLLVDHGGARATNFSAAISPCTNYVTEVGEPSRNSGRTTAAQWLRVAFHDFVTADTTTAAGTITGGIDASIGFETARAENKGMSDLIALGTVMSVHLCGGKAIPYRPGRIDALHADPTTGVPEPETGVDETLEEFGRAGFNRQDAIALTACGHTLGSVHHGGFPEVVGPEAVTPTNTNGGSNFDSTRGAFDPLVVHEYIDSTGSRGGALVTSFNETARSDLRLYESDGNQTMRGLYDMTTEAFQDTCAELLGRMIDTVPSGVRLRDAIAPMAIKPVNVTWDFNGETDRLVLSGNIRILWGAPTVTKVVTFSSGDLVTSLSPEPEKRYTAYGMSDTYFYPFSIPGSAIGDATSFTVSGDNLTTQTFPISRAGQTFFVPSMSTATGTSASFTVASSTDSGLGEERLAVQVAAPVAQPLTLAPKIVTATVNLIKAEDTKSGFQFWKGSYDVYQQVTGAISLTLTQGGETLDHLLLGAGVAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZH2</accession>
    <name>A0ABR1WZH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Tricalbin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_003528</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671461.1">
        <property type="nucleotide sequence ID" value="XM_066807843.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040903"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04044">
        <property type="entry name" value="C2A_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04045">
        <property type="entry name" value="C2C_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04040">
        <property type="entry name" value="C2D_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21678">
        <property type="entry name" value="SMP_TCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037761">
        <property type="entry name" value="C2A_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037762">
        <property type="entry name" value="C2C_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037756">
        <property type="entry name" value="C2D_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056910">
        <property type="entry name" value="TCB1-3_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017147">
        <property type="entry name" value="Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052455">
        <property type="entry name" value="Tricalbin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980:SF2">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24920">
        <property type="entry name" value="C2_TCB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037232">
        <property type="entry name" value="Tricalbin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00360">
        <property type="entry name" value="C2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="13">
        <location>
            <begin position="202"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="12">
        <location>
            <begin position="402"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="12">
        <location>
            <begin position="549"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="12">
        <location>
            <begin position="686"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="12">
        <location>
            <begin position="1053"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="12">
        <location>
            <begin position="1290"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="841"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1222"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1414"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="848"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="861"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1270"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1415"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1441"/>
            <end position="1454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8088567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1454" mass="160622" checksum="A439E61425CB20CC" modified="2025-10-08" version="1">MATEQSAAELKQQGAIEAAENPESNVTAEDAQKKMVEESKNAGVAAYTFDPDASPEEKRRQAKAAVPDELRRKHKAVAVVTDADDGSKADYDLPTPSRADALDVPKDKEGNLFTDDASEEERPEDIAARVGWQQRYGWPHESPMTGESLLDHQTWLEGKVPDHMYGEWYHNAGVIIFACLASWVVAVLGGGEVSLMKKTDMDAESLEWINAFMLKFWPIYQPVLAETIINSVDQVLSSATPAFLDSLKLKTFTLGSKPPRMEHVKTLQAEDDMVIMDWKFSFTPNDTADMTAKQIKNKVNPKVVLEIRVGKAMISKGLDVIVEDMAFSGIMRLKLKLQFPFPHIEKVEMCFMGRPEIDYVCKPLGGETFGFDINFIPGLESFILEQIHGNLQPMMYHPNVFPIEVAKMLAGTPVDQAIGVVAVTLHGAQGLKNPDNFAGTVDPYVIVSLSRRGELARTKTIKDTSNPRWNETKYVIISSFHDSLDLEIFDYNDIRKDKELGIASFQLDQLEEFNVFENERLEVMSNGKARGVVSADVRFFPVLEETTLPDGKVEPPPETNTGILRFTLHQAKDLDASKSMVGLLNPYAALLLNGKEIHHTKKLKRTNNPIWDDGYKEILISDRKNAKLGIAIKDDRELAGDQLVGTYQIKLEDLLEMMEQGKDWYNLSGVSSGRIKVTAQWKPVAVTGDLVGTGGYQTPIGVMRLHFKNARELRNFETMGKSDPYVRVVLSGIEKGRTVTHRNTLSPEFDEVVYVPMHSSRDRLTLEVMDSEKMGKDRSLGLVELMASDYIHQDENGEYLVNDRKPLLEDGLRLHGKGIAKGVLCYTASFYPCLNVADPEDEEEEEAAAAAAAAAAEAAAEESKNDLEHTRSADAGKITALERKPTQNGQGAPLSPAMPPITPTSPTFSDRKSRDAARQVPKIRLTPEELLKHESGFLIFHFMEAEMPKGGSHVEVYVDDMLFPSYVSGSAKHKSHKFDEIGDCFIRELDFSRLTLKVRERKEKPGEERDEDHTIARLTGNTLDTLKQCLNNPTVLKFKDDENRGTWVKVSLKYIPVRMELDPSESINNMGNLRVDVLDAAGLPAADSNGKSDPYARFELNGQDIYKTKTQKKTLDPVWNEFFEIAVPSRTAAKFHVNVYDYDFADKPDFLGGADINLEQLDPFKAKEMKLLLDGKSGSIRIRLLFRPDYVTRTRMGTGTFSGTFGAPGRIVTGVAGAPIKGGAAKEEDSNGALMPPNNIDVPSIVTNGGEASAPAPGLRRSTGPRLDGNESPETPPSSSHSNHHQRTTSMGGMSVHSMAPGAAGAGTATFTVVSATGFPPSADAYVIIRQLAPKEKVVGKTKHHESATSQIQYDETFKHTCTADTQFRLEVKGHHTFGSDDDLGEALYFVDDTQSGGEKEIKVGTGAVIIKSSFVENQPRPTTSSDSPRGGNTMRRSFLSKKETRPGRETTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZM8</accession>
    <name>A0ABR1WZM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PEBP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671520.1">
        <property type="nucleotide sequence ID" value="XM_066807902.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040962"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00457">
        <property type="entry name" value="PEBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049556">
        <property type="entry name" value="PhiB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="22218" checksum="D7BA9AEE5D177158" modified="2025-10-08" version="1">MSALIEVTLSWLLQNFKHRDDKLFIKGPAFADHPAPTITVTSPDCGETDAQLSVVYTADGVGHHPELSWTAPAGIRDQVREWLLVSEDPDAPLPTPIAHGVFGGIPVAKTSVKAADFDIQDDGQAMLKGGFHYGVTRRGVPYIPPRPLLNHGPHRYFYFVVALSAPLESGLLKAKATREQIAEAIVGKVVGWGQWVGSCERTWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZW5</accession>
    <name>A0ABR1WZW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671558.1">
        <property type="nucleotide sequence ID" value="XM_066807940.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041000"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="330" mass="34961" checksum="9C5F9A26844CF849" modified="2025-10-08" version="1">MSDSDLYVSNGTCYFDRGQIANRHFIPCGNAVVNGPQACCYEGDFCLSSNTCWDNMTIVTYVAGCTDPSFSSSKCIQKNGYPDQQWVAMARCDGLDVDIWSGCAKHPNVTAIQKEDCDCTASAPLIRKPNGKTSFDNIASLPQTIMGSISFNPTALPTRGAGNASSSTSGTASPTAGSSGDSSSGLSHGAQIGVGVGVGVGVGVGGAILLAIIAFIVYRLRRQKKSAPPPQYETHHQEQQEPRSQVASPTSGTPENLIEHSRSRRSLRASPGQKPSPPNSARACGTNQNCLAIQPCDPSCRLAGLLRRVTYRNCQERHRDGRACFLSPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X049</accession>
    <name>A0ABR1X049_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5672 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671623.1">
        <property type="nucleotide sequence ID" value="XM_066808005.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041065"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043729">
        <property type="entry name" value="DUF5672"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18922">
        <property type="entry name" value="DUF5672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5672" evidence="1">
        <location>
            <begin position="104"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="285" mass="32428" checksum="86CAC6E28F0923D6" modified="2025-10-08" version="1">MFVYESYDSDVVRLANQTAHNITWDDVTGEKKAGAAPAKVTEKYTDRVAVIVENRPLQNLVPTMLHFHSMLGPEWPMIFYTVPTTSEALNRSAPFSRAVAEGRITIQHLPAEYTFETHHSVSLFLTGRWLWEDLAPYAKVLMFQSDSIICSASEARADDFIEFDLVGAPIGEQWGAGYNGGLSIRNRAMMLDVLDRHSFQDDMVPPYEDQWFYKKLRELPPRADGTPAAYLPDVDTARRFAVETIYGERPLGYHQPMRFNKEKKDEILQYCPEIGMITGAAFFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X079</accession>
    <name>A0ABR1X079_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">C2h2 transcription factor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003733</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671666.1">
        <property type="nucleotide sequence ID" value="XM_066808048.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041108"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="110"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="141"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="171"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="270"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="307"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="479"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="479"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="597" mass="66596" checksum="4C8E24B351423C9B" modified="2025-10-08" version="1">MKRLADAADLDEEDYQPFTKRGRVTTPSTAGTDHHDGSMFDGESDYMDENGSIHAAATPMTSFSGASPPARKFPSDYKTIKCTWPNCTKSFNRPARLTAHMRSHNNERPFACPYEDCDKDYIEEKHLKQHIKGTHTKERDFTCTEPECGKSFTTSTRLKRHQAVHLGQEKFRCRDFPPCSLSFRKRETLERHIRSDHENKPAFACTELHAETGLPCVAAFDTSNALKRHSEREHGEPRFWCEECGNKEGGVNIGFPTMDLLQRHMQTSHIGCTFCDRVFTSRENLDAHVELDHTKRSKGGRKGQGSVPCPHPGCGKTFSKKSNLTTHYNSIHLGKRWICGEVDFPKVEWDKSNACRQGFVTKGNLLEHVTHVHLRVPRPPTKKAVSKKPNDMVGMLAGHSATTRYTIPCTVLGCSFKFASQGDLQTHLHIEHGKSGIRTPSETDSGAFPFTGFSGASTPALSVSDEQSLAGQFPVTTTSQTVQSLPAPTGQQLSPTHPITTAPQFDASLPAAGEHHFGTEFPVVSDSQFSHQSINSEHLPTHTNNYWPHPSPHTSSHFDAPVFAAQQPDDQWQHDEVEMRQLIGYTELDGFIDPALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0J8</accession>
    <name>A0ABR1X0J8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein arginine N-methyltransferase 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Protein-arginine N5-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Type IV protein arginine N-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_003918</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671851.1">
        <property type="nucleotide sequence ID" value="XM_066808233.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041293"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017408">
        <property type="entry name" value="Arginine_N-MeTrfase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051038">
        <property type="entry name" value="RMT2/GAMT_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026480">
        <property type="entry name" value="RMT2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379:SF1">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038148">
        <property type="entry name" value="Arginine_N-mtfrase-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51559">
        <property type="entry name" value="SAM_RMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RMT2" evidence="14">
        <location>
            <begin position="218"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8088957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="489" mass="53795" checksum="3C18797C562E7B32" modified="2025-10-08" version="1">MGEPSNNQDALEARIPPSCPASISGILTQAWNHDLASLKPLLDVPGRASVQEPTTGETPLHAAIRSCGAAGAAASDLEAAKNVLEELFFNGAIWNDVDSNNETPGCVAARLGQADLYEMCIGAGVRAELLFGLLESYEELESMDEDDDEDEEVVDITADAAAPDGEEVPDLVVETNNEGHAAEKQPTKKKEEEEEEETEILESNPDRAFVAPSTSEAQASQVDSAEYLRSNLTYSAGKLTDDAANGVMMAWETSIMRASVDTLLPEQQPGRKVLNIGFGMGIIDGMFAATKPARHHIIEAHPDVLSHIATSPDCQFGPAWEASAPAPGAYKVHAGKWQDVVPKLLEAGETYDAIYFDTFGEDYAQLRMFFTEHVPGLLEEEGRFGFFNGLGADRQICYDVYTKVVEMHLSDAGMDVAWQEMDVDMQGLQEEGKGEWEGVKRRYWTLNSEYSFLLLSYSTPFFSFQTMLTNMYRRIPTTNLHFHEVKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0N9</accession>
    <name>A0ABR1X0N9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADH:ubiquinone oxidoreductase 12.3kD subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003891</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671824.1">
        <property type="nucleotide sequence ID" value="XM_066808206.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041266"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039993">
        <property type="entry name" value="NDUFB10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="122" mass="13802" checksum="910BA8EC12A014DF" modified="2025-10-08" version="1">MPTPESEAFLAKKPKVPPTFDGVDYDDNKALKAAQDSVVREQWVQVMMGRLVREELSKCYYREGVNHLEKCGHLREKYLQMLDKHRVRGFIFEQQNYSTPSQVAALAGAADATAAAKNSKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X121</accession>
    <name>A0ABR1X121_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF1772-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004058</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the anthrone oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671991.1">
        <property type="nucleotide sequence ID" value="XM_066808373.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041433"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013901">
        <property type="entry name" value="Anthrone_oxy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042">
        <property type="entry name" value="ANTHRONE OXYGENASE ENCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042:SF1">
        <property type="entry name" value="DUF1772-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08592">
        <property type="entry name" value="Anthrone_oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="19790" checksum="204B549EBF61B826" modified="2025-10-08" version="1">MSSSTNTPALRALQATNAAVLTTTAGLNLGLSFFVMPRLLESPTPLMLRQWGRMFAVTSRFFPPAMMVPGLVHAVLAYYYYTVAAAATTAARGLQKGAVYNAVAALVALSVMPWTLGLMVPINEKLLRKVDAAQSLGANEVEGREVGVKEEETAHALVDRWALLNLYRGGDVLVSGCLGLYAALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X281</accession>
    <name>A0ABR1X281_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004487</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672420.1">
        <property type="nucleotide sequence ID" value="XM_066808802.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041862"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="167" mass="18269" checksum="D7E51240F098211E" modified="2025-10-08" version="1">MPSSNQSSPNNHDIELKLFPIKEDFSSSIAQGSHDTMREPIYDDFATPSGGLHGHHHLHHPSATPPRFLRSWADGFRRDPNQRITPKDPISDIMAGESGSLLTQQTSHNGRIPSGHSYDMRMAALSTAQSSLLRRLKGRHLQMIAIGGSIGTAFLCLDSRNFASAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2B4</accession>
    <name>A0ABR1X2B4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672358.1">
        <property type="nucleotide sequence ID" value="XM_066808740.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041800"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905:SF2">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13714">
        <property type="entry name" value="PEP_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="311" mass="33447" checksum="E21F601887A05BC9" modified="2025-10-08" version="1">MAAQQKGAAKLRQYLADPEKIVICPGVHDGITARMALHVGFDALYMTGAGTAVSRLGQPDLGLTTVDDMAANAGMIAGLDRSVPVLADADTGFGGPLMVARTTEKYILQGVAGFHIEDQVTTKRCGHLLGKELVEAETYWARIRAAAHARERMGSDIVIIARTDALQSLGYDEAVRRLKGAVEAGADVAFLEGMESREQMREVVQALSPTPCFLNMVGGGVTPLINAREARELGFKIVIWPMCGMSAVYLGMREFARELKDTGEIKERYVTADDGTRKVDGSVRDVFELCGLKECSAFDQEVGGSSFLKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2I3</accession>
    <name>A0ABR1X2I3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_004568</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672501.1">
        <property type="nucleotide sequence ID" value="XM_066808883.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041943"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018944">
        <property type="entry name" value="DNA_pol_lambd_fingers_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF28">
        <property type="entry name" value="DNA POLYMERASE LAMBDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14792">
        <property type="entry name" value="DNA_pol_B_palm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10391">
        <property type="entry name" value="DNA_pol_lambd_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81585">
        <property type="entry name" value="PsbU/PolX domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase X" evidence="11">
        <location>
            <begin position="482"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="128"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="276"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="411"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="349"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="415"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="470"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8089607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="840" mass="93063" checksum="78044509DD86BEB1" modified="2025-10-08" version="1">MEPTLGDKVAFFQELQAFQAEDGDEESWVKEDPHRNAAKAFMKAAAGATSSSMSPDLVRPVNRLVAANNPFVASTPARTASDSAIQRTKNNELSGIIKSTPPNSHLVPHLRKTASEVIDLFTISDTPIPDSTKASTKQQPQRRVSDRLLRRRATGSPSASVQETPSFKMPKRKKDVPIKMVPEADRCFAGLTLFFFPNSDANGVRKKRIDKAREYGAIWTRSLKDATHVIVDKGLTYADLEPLFEGDGDPSKKIVVNADFLIDSWTHRVLVPRNQDKYQVPGKPDSQQDNADPPEPSQSSDQSLVLKERRSKRIRLSSQNTTRGSYSASQAAAQSTEDAVVPSTQPVAASRSRADPSSSTTPEEGNPVGSVREGRRDSQSRMASEVDSENSSFQDELSQCIGHIMEFGDDVVIPGEDEDGSPEPEDGEESKGPEDIDDGEEPYRSEDERPAKKTRTSRTSAKVAKGAEGWQSSGSQGVESKNPNAETINVLLELADQYAKMGSEPWRTTAYRKAAGALKQQSVKILTFAQAIAINNIGESSAEKIEEIAKTGRVQKLQNLQNDPMIKLRGLFTKIYGVGPNQADRWIRQGYRTLDDIREKAHLTTNQRIGLDRYDDLNTRIPRKEVEALGAHVVRAARAIDRDVQLVIGGSYRRGADSSGDIDIIITRQGTSSTSQLIGFLDELVSKLTDEGFLTVALAAHSKNRVDDGHDSKWHGCCVLPKDDYPGDVSAEADDNDGDINKNKEEWRPIWRRIDLLLVPESQLGAALIYFTGNDIFNRSMRLLAQKKGMRLNQRGLYKDVLRGKGNVKITEGELVEGEDERKIFRHLGVHWREPHERWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2Z2</accession>
    <name>A0ABR1X2Z2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672677.1">
        <property type="nucleotide sequence ID" value="XM_066809059.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042119"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39398:SF1">
        <property type="entry name" value="CSN8_PSMD8_EIF3K DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39398">
        <property type="entry name" value="YALI0F14311P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35824" checksum="B59626EB385DA6D0" modified="2025-10-08" version="1">MRGRGGPRGQRGGRGGGRAPSGPWSRLKPVELDPLEAIGLPSKGDNRLLDFKTQERYYTKIVERYMSFCSDAGERQELLRRFSSLQLAETPTLRPSRRRRLLLLSPAALLDPSRGTQRAPPLSLWSPLCPPPPTRKGSRTCWRRLRKLREGIVASKRADDFAVQAYLFCIRLSVLVKHPESYHPAILHLLRRIQPLHPMTSVETSEVVGYLILDTACRRNDLAEAYSLRTRYRLRDPKIDGVLDALAHDNYVLYKRLRRSVDGHKAKLLEFGEGPCGSTRSSASGVATSVWNWSSWRSARTRRGWISLRMTAWAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4F3</accession>
    <name>A0ABR1X4F3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673180.1">
        <property type="nucleotide sequence ID" value="XM_066809562.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042622"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039258">
        <property type="entry name" value="ZNF511"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21354">
        <property type="entry name" value="ZINC FINGER PROTEIN 511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21354:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="271" mass="29607" checksum="4323C67D4B6A7833" modified="2025-10-08" version="1">MKRSREPEEDNSSEYLSADAPSDNGDVGDVGDGDAPTSGTRSSKNKQPAAKIIQVDESAVDDSSTIVMREPLAFRSYTDYETHYHKAHSNRCFECRKNFPSDHLLSVHIEEQHDAFAAVRRERGNIQTPQKRRMHLIDKHMYPKNFFFGVTKDGIDGRTSLLIGDGHRRRGSSISQNGSGQKAAATARRHSLRSQTAEAAADESTSPAQHHAAPTDDIKGSNVASNDKVAPQPESADVAMAELESAMSALQFVPPSIRFGRGKGKSGFAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8Z4</accession>
    <name>A0ABR1X8Z4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673822.1">
        <property type="nucleotide sequence ID" value="XM_066806526.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039586"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF1">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="173"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="708" mass="79759" checksum="C3FDDD842A7DA5E4" modified="2025-10-08" version="1">MAAPPESLSGCKTCQGIWRRFTDLTFKDAVNFGPPAAALSTPCASHRPLVESFVKVFRSENRDIYRVTADMGIRRPGKEASPRLVESYSGGVFWDLLLARPEGKPDHPGTTRVLDPDWADLDMLKRWKDECLSSHGVKCENPINVSPLRPAWLVDLERKCLVPGSYAAEAAPYVTLSYTYGKYVAPGIDAETLVELQRANALGLPEITSKYVPPMVKHAMGLTSVLGERYLWVDLLCVPDGDPTLAKEEHLMQMGAVYANAVVTIIAADGDVEKGLPGLRNISGPRELCQRVIPFGEENKLVVRRPQVYRFDGHSSTDLPYYRRARTFQERLLSPRKVYFHEKELHWECACHVLHEEQVQPAAETIEESTDYPDISTMLAGFPDLGALDAVVDRYNARDLRYDEDALPAISGLLTVLSCAFPGGFLYGIPEMFFERGLGWRHGPSLMTQVRRRSPSGRPNEEGQSPSMSMSDLPSWSWIGWQGRMTMGRDGEAARINHRSHEIEETVPITKWYAARSSDTDPSQRRAIKSTWFEDREKYKDFSEPLPPGWSRHEAPEFDHFGRPRLYPDGCAEYVFRHEAGHSESWYYPFPMPEAGTPGTMPEQTPYLFCETTRVWLWGCQADRMNQVKLYDSSGGEVGELYLPNRSDLGAFPRRGIDDGCRNEREEMGLRVELVAICKSRVYEYSLDQDKRAIGPQSRGPSGILCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9C3</accession>
    <name>A0ABR1X9C3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674028.1">
        <property type="nucleotide sequence ID" value="XM_066806732.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039792"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8092056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="377" mass="41958" checksum="77FFF1B18FECF4E7" modified="2025-10-08" version="1">MSSPRKLSWDHNTHTPPPCRIIMPPRQDNSRRIAVPRLKTANFDDPQFTLWDIPPHAVLDAMLAHPATPAYLSGMTNVQCYDLLREYATLTLTLADPARDFRQVFQTMLEHRRPEAEAAGRPDQTRALHATLHSIAAMLLQGPPGRVSHLALHIMHALVKLDYPPSVMTLTRIALTSRKLDQPQFAPAVERFERLVKSLAAYRPSAAKTAKKGKSGSETDTAVGTKPDEEDAEFRPTQAARGRYREALNYFEAALGGSPTKLSASSPRFGWQILCLEEMGHCYAKLGDTAKAHAAWKFAAEELDDKDCMALYAVHALQPDDPARERLLLKAAVSDSKLAVHEMKKIYHEKVEKQMKTHTKGKKGKGEGRSGISCSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9H0</accession>
    <name>A0ABR1X9H0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-dependent RNA helicase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002389</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674000.1">
        <property type="nucleotide sequence ID" value="XM_066806704.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039764"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF145">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="693"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="951"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="233"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="387"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="892"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="904"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8092028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1471" mass="165409" checksum="C73A7F4EBBC1686D" modified="2025-10-08" version="1">MAPKKKKTKAAANPARGFATTSVASKPVTRIEQAEEAIATPNGKAATPLSAQEGKAAGATSENAALAPSDPTVARPTKPDLSPEEFEKQLLESELQLLVEKHAQKSSAMPSVKRRASRRIDAEPVNVRKWLPQELMDHILDLIQAEHRFAASSLGPDTTSSGRLLPEEELTMKLWTLQQTLESAGFTEEKVASVLQYILEIGPNIGGTTKENIWGLEEALDWLARECSRDELPDYDQRGRTFPRLADTPQDSPLASGANTPRLLEPSGTATPAAKNGSAKSRSSRAASPKKPAPAFDSDIEPDDLVPVYLESKAKLFHIQRPKQDVKQTKAGKVKDVNGSQTVDMEEAKLLAKIEHIEQDVLFDKISAEQTWRNERVILEREYAAAKKQEAEESEARDDKQDDASDDEDEIAREAKKMATEVLQQDSADDEQSLSDLFASLPVQEVDPSTGKTENVINSTDGSKVFIRNFGKWTGVSPMRALEETCRSRDPAVKLQYRLISEASFANRHVVIVSWSKPQELISTDIAHIESYAYPHQFSFGMADVATPDSKQSEAYVATAALFAIFHSTKEEKVFMRLPAVWKELWNEFAQARKSHNDAQDRASIKELRRMVRQRQDQEEEDGILLQGAFRGRRANQSLNDSGDSGSDREKGQSINPEFYQRIWANKCGTPRYQAMLQSRMQLPMWHFKQQVLDSIEREQVVIICGETGCGKSTQVPSFILEHQLSLGRPCKIYCTEPRRISALSLARRVSEELGEGRNELGTSRSLVGYSIRLESNTSKETRLVYATTGIVMRMLEGSNDLREITHLVLDEVHERTIDSDFLLIVLKKLLLRRKELKVVLMSATVDAEKFSKYMGGAPVLNVPGRTFPVQVQYLEDALELTGYSIDQKHPAEKSIDLDDDPTENDKDAGSARDAAKDLRQYSAKTRNTLAQFDEYQIDPELIVQLIGRISVDPQYIDYSKAILVFLPGIAEIRALNDFLLGEPFFQRDWEVFPLHSTIATEDQERAFLFPPHGVRKIVLATNIAETGITIPDVTCVIDTGKHREMRFDERRQLSRLIDTFISRANAKQRRGRAGRVQEGLCFHLFTRHRHDNLMADQQTPEMLRLSLQDLAIRVKICKIGGIEETLGEALDPPSAKNIRRAVDALVDVRALTAGEDLTPLGLQLAKLPLDVFLGKLILQGTIFKCLDMAITVAAILSSKSPFSAAFGQRTQADQARKSFKRGDSDLLTVYNAYLAWKNVIQQGAPVFQFCKKNFLSHQNLLNIEDLKGQLIASLVDSEFLQLTDEERRTLKRLRHSNRRSQFFDMPHRVNINSNNDVIMSSVIAWSFYPKLLMRENKGFRNVGNNQSISLHPSSVNKGNMELKWLSYYHIMQSKQFLNAHETTAAEAFAVALLCGDVRIDMYSGVLVLDGNRARFSVPDWKTMLVIKVLRARLRDILNRSFKMPGKLLTEQQEKWMGVWQRIFSQDFGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAH1</accession>
    <name>A0ABR1XAH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome c oxidase subunit 8, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cytochrome c oxidase polypeptide VIII</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_000330</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
            <topology evidence="1 10">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome c oxidase VIIc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674418.1">
        <property type="nucleotide sequence ID" value="XM_066804645.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037705"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.49.10">
        <property type="entry name" value="Cytochrome c oxidase subunit VIIc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004202">
        <property type="entry name" value="COX7C/Cox8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036636">
        <property type="entry name" value="COX7C/Cox8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13313:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13313">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT VIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02935">
        <property type="entry name" value="COX7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81427">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8093645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="80" mass="9264" checksum="29E6E23C5D3F22A4" modified="2025-10-08" version="1">MSPQSVLRASPRAANMISRRMFHATRARLSSPYHYAEGPYTNLPFNTKTRFFGLRYWLYMATGFFAPFGIAIWQTNKPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB98</accession>
    <name>A0ABR1XB98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000553</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674641.1">
        <property type="nucleotide sequence ID" value="XM_066804868.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037928"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08234">
        <property type="entry name" value="threonine_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="32"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="5">
        <location>
            <begin position="178"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="349" mass="37791" checksum="C737A992A07B401E" modified="2025-10-08" version="1">MAPELPKTMKALRYEKPEDWSIVQVPLPTLRAGDVLIKVKACGVCGTDLHIHEGEFIATFPLIPGHETIGEVVAMADDVTTFQIGDRVAADNSELCGHCFYCRRGNALLCEDFKAHGVVGLDGGFAEYCSYTQGKLFKINNISDVDATLIEPASCAMHGLEKIAPKAGSHALLIGAGPTGLMMAQFLKNAGVSQLTIAAPEGSKMDLAKSLEAADKYVPLSRKDATPQWEQIKKDNPYGFDIVVEASGSAKVLEDSINYVRRGGKLVCYGVYPDSARVTWPPSKIFGDEITIIGSFSETFMFPATVDYLDSGKVKTAGIVNKTFKLEQWGEALESIRNKSAIKACIIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBF2</accession>
    <name>A0ABR1XBF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lin1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674691.1">
        <property type="nucleotide sequence ID" value="XM_066804918.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037978"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039905">
        <property type="entry name" value="CD2BP2/Lin1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138:SF3">
        <property type="entry name" value="CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138">
        <property type="entry name" value="PROTEIN LIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="2">
        <location>
            <begin position="386"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="442" mass="49915" checksum="E37D084482992DA4" modified="2025-10-08" version="1">MSSRYGAARPKRAGEQFARAHHADEDAATEPGSKKVKFDVRNPSALALGGDEEEVKDEFLEADAEVIRGSAATKRGAVNIDGYDSDSDREELGARPEAKKVAEKDKDEDMDDMFAEADEDETEDRVDDTTTKKSKEVRFLEGADIEGQDMRSRDTAQIRLDGQESDDDDEEEIALAIQEEDVDEEVGAGGLKKHAPKVEAFNLRAEEEEGRFDESGNFVRNAIDRDAQHDRWLEGVSKKEMKKAAEAHEKREADLRQKRKEDGDLLTSDLLKSLILKLELGETALEALARLGRGQAKSKKVPKWKQKKMKPEAMDVDAAEKEDPEQVRIKEAIDSITDAADKLLSRDRPDVYDRERELLVREWSRETQEPWVEPRRETAAEEDAPAKMWEYRWVDGRDGAPKQGPYDGRTMEAWQNAGYFGEGVEFRVVGDEDWAGPPSSWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBY1</accession>
    <name>A0ABR1XBY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Double-strand break repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_000778</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Core component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases. The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. Within the MRN complex, MRE11 possesses both single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. MRE11 first endonucleolytically cleaves the 5' strand at DNA DSB ends to prevent non-homologous end joining (NHEJ) and licence HR. It then generates a single-stranded DNA gap via 3' to 5' exonucleolytic degradation, which is required for single-strand invasion and recombination.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the MRE11/RAD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674866.1">
        <property type="nucleotide sequence ID" value="XM_066805093.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038153"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.110">
        <property type="entry name" value="Mre11, capping domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003701">
        <property type="entry name" value="Mre11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038487">
        <property type="entry name" value="Mre11_capping_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007281">
        <property type="entry name" value="Mre11_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139:SF1">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04152">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000882">
        <property type="entry name" value="DSB_repair_MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01347">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 16" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="11 16" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 16" id="KW-0464">Manganese</keyword>
    <keyword evidence="15 16" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 16" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mre11 DNA-binding" evidence="18">
        <location>
            <begin position="281"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="564"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="344"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="574"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="605"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="678"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8094093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="703" mass="79676" checksum="A57035D0FA693A2F" modified="2025-10-08" version="1">MASSELTEADTIRILVATDNHVGYGERDPIRKDDSWKSFDEILRLARKEDVGHPIMFEVDMVLLAGDLFHENKPSRPAMFQVMRSLRKNCLGMKPVQLQFLSDAVDVFHGAFSHVNYEDPDINISIPVFSIHVSGLVNYFGRVPEVDNISVKPVLLQKGSTKLALYGLSNVRDERMYRTFRDHHVKWFRPNVQTSDWFNLLAVHQNHHAHTATSYLPENALPEWLDLVVWGHEHECLIDPTLNPETGFHVMQPGSSVATSLVPGEAVAKHVAILNVTGKEFKVEKHRIKTVRPFVTRELVLAKDDRFKSLAKKKDNRSEITRRLMEVVEEMIAEANADWRSIQDQDENQDEDQEEGENVEQNEAPLPLIRLKVEYTPPEGGQFDCENPQRFSNRFAGKVANTHDVVYFYKKKTIQRKEKIEEISEETLAELGLNAIEVERLVTEYFEKQTLKILPQAPFNDAVTQFVNKDDKHVMEQFVDDQLTTQVKQMMSLGDDQRGDEEILNVMQKIKAREEKQFKAGEVKNRRRIVKPKPDGWDSDLEGHWEDQEGVITIMDLDDEVVEDSMPKKKGRPAKAPAAKAAPKKAAAAKKAPAKGRGRKAGPFVDEDDEEDDDIIMDDDEAPAPPPKRGAATRSQPARSQPTRSRPSRAAAAGTSNKKQTQLNFSSQKGSQSNALEISDDEISDDDDDPFETMAASKTTRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC00</accession>
    <name>A0ABR1XC00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675009.1">
        <property type="nucleotide sequence ID" value="XM_066805236.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038296"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="73" mass="8259" checksum="61E05E6741C9E55A" modified="2025-10-08" version="1">MPRSSRTDSSSSVSSVGSQVSFQLPTELSVRDPIVRRATPFPFKHQRSESREQPRMDQWPTVLASFPPLSSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD50</accession>
    <name>A0ABR1XD50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYB transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001204</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675292.1">
        <property type="nucleotide sequence ID" value="XM_066805519.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038579"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053095">
        <property type="entry name" value="Actin-binding/GATA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23246:SF24">
        <property type="entry name" value="MYB DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23246">
        <property type="entry name" value="NEW-GLUE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="8"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="28593" checksum="679A5934D76A1D8E" modified="2025-10-08" version="1">MAPHAAESPAKKQSKWSAEEDALIIELRGNGMKWEDISKRLPGRSAISCRLHYQNYLERRSEWDEERKNKLARLYERFKPEMWAKVAEEMAIPWRAAEAMHWQLGEHDMARRAGVVPFALSAARPIITRKESMPPHMPAHLEHGPGGYDYPPPGGPLAPIQAQSQQRPGMLPGLAELTTGVSPYSTPAYSIGIPSVSPAQSATASPGPFIPAMAYPPLEPAGSKRRRSPDLLQAEANRRRHLDPQPLERVMPRHMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDP4</accession>
    <name>A0ABR1XDP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675566.1">
        <property type="nucleotide sequence ID" value="XM_066805793.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038853"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046694873" evidence="2">
        <location>
            <begin position="19"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="302" mass="31870" checksum="02373AE4DB85BD0C" modified="2025-10-08" version="1">MQLIQLLFPLTLLARCSAAEATATTTAATSSLPTLNGEDTLNATRQGTALNILGIATSVVTDIVHEIFGIIKADDDKNPNGQKSQYQLKGARHEHFELDKFLVGSYGYEIWVFESGSFTLEGSRDAKEWGWRGCRDGQKSDLVGPHVEFCDPKKQKQPPQQSQQSSSTTRTTTKKQQHTSVTHPTSSTQHPKTTTVLRTVSQKPTTVVQTQEATVTAAPSGGGGDGSVDSTADPVFTTAVNGGDGSGNSANNPAANDGQGQGQQGGSSTKNPSSVGVPKLTHQSATYVAVVAAFVALCFMMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE60</accession>
    <name>A0ABR1XE60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HET-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675717.1">
        <property type="nucleotide sequence ID" value="XM_066805944.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039004"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="59"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="492" mass="55128" checksum="6B997EA4C2FC9C24" modified="2025-10-08" version="1">MVPNYLLVLSTWATRRLRTWSFWKAKGCGENTAHSATAGAHHIHKRFLPPKKRLEDRLREISFDDLPRTFQDAVQITRELGMRYLWIDGLCIVQGDKHDWASEAERMGAVYENASLVIAASGSASAQKGCFITGTRDLCSINLPYYTEDGQSEGYVHACAHIPGNRWFPGEGPLQNRGWALQEAYFARRAIHFMPGGPSWSCRELDLDERNRKGKPFFHKDWENVVENYSERRLTYESDRLMAIQAYANELQKKTGNIYNRGIFLSRLPEQLLWTNGNMSDAEDLAEDLVGLPSWTWASKGGLKVFLADRISECVSPLAPVVAHDKFRIDGSGSLLVEDCAVLCHTSGGRAGGINEPLDTQLCPIKEMVGMAVNYKGCVPFYLTEPSDSEYPRLRGVAYFDEDYKGTVHSLPLTTAAGRNHSRTRYMSSNDVESDTESSSSSTCSSTSPESQHDGPDYTSYMSLLVYVVMDRRSLSVWLAFPAPLPSFRAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ26</accession>
    <name>A0ABR1UQ26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Coatomer subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_015254</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9 10">Cytoplasmic vesicle</location>
            <location evidence="9 10">COPI-coated vesicle membrane</location>
            <topology evidence="9 10">Peripheral membrane protein</topology>
            <orientation evidence="9 10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9 10">Golgi apparatus membrane</location>
            <topology evidence="9 10">Peripheral membrane protein</topology>
            <orientation evidence="9 10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660453.1">
        <property type="nucleotide sequence ID" value="XM_066819568.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052628"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09254">
        <property type="entry name" value="AP_delta-COPI_MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14830">
        <property type="entry name" value="Delta_COP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027059">
        <property type="entry name" value="Coatomer_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121:SF0">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4 9" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="12">
        <location>
            <begin position="273"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="154"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8061033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="512" mass="56660" checksum="8A9EB129B4A1F772" modified="2025-10-08" version="1" fragment="single">VVLAASICTRGGKAVLSRQFREMPRSRIEALLASFPKLADSSTQHTTVEQDNVRFVYQPLDELYMVLITNRQSNILQDIDSLHLFAQVVTSTCKSLDEREILRNAYELLSAFDELVTLGYRENLTISQIKTFLEMESHEERIQEIIARNKELEATEERKRKAKQLEMQRKDAARSGRAGVPRTPVYPTYTPPARPSQDTYDSYEAEKNKAAHKPTLMKGKGMQLGKKSKTTDMFERVRGDMGSEVDDSPLVPVAAPTPAAEPAAQRMSSTLDRDAIHITINESISAKLSREGAVNSLAVSGDLTLRISDPSLTKVKLDLSAHASHGAQFRTHPNVDKGAFNSSKVIQMSNIARGFPVNNAVGVLRWRASPKADDDTAVPIQFTVWVNKGSDGNYGLTVEYELTGGEELKDVSVVIPYATSEPSVSSFDATYEVSGDSLEWSIGTVTADEPSGSFEFEAQADDENEFFPMQVRFSKTTPYIDVDVSSVSLVEMNEEVTFSKDIKSTADSYLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ87</accession>
    <name>A0ABR1UQ87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660497.1">
        <property type="nucleotide sequence ID" value="XM_066819612.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052672"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="173" mass="18867" checksum="D9DB628B93112FF1" modified="2025-10-08" version="1">MYSVVTRGKAKQNVIIAGCTLHERDEARRQLRYDSIFGAVIKEAEMLGEIGQLPGAASVLSPAPAVVDGNFIEQPDGSVGFKQEYLDHMNNFKPQPLESISEKEEPVTDTTDASASAASSTFVITRQLGGTAAKDMAVPRPYDPEEDEDLVFLDLDLEEEEDAVDAEDDYVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTA3</accession>
    <name>A0ABR1UTA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660761.1">
        <property type="nucleotide sequence ID" value="XM_066818573.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051633"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="374" mass="42928" checksum="A9858BBF6F7C41BB" modified="2025-10-08" version="1">MHFTDPSRRKLVSCILLPQIPGLGSDALKSSQRILGIIVDSKLCWDEQISELDAKVTKRMGYLKRISGKTWGPTLQRMLQLYKAKVRPVFAFGCAAWFLHPIDGPEFSDGRKFRWGLKDSHVRRLVQMEDRCLKQISGVFGGTSFDVMRNQLSMESLDIFLYYRHITFRIQRLGSPEHRTLHERRIRPVHPASAPVALAAWPLWQHLNNILDNIAQDYKKHIEAWLREAPGPEDREPDWRLSKRKKRGMKKWFAAQTAMRMDVRFQECIALRCNKGTHEARFKGHPVTPRPVALSNKWSDNCIEKCDGMSRAESTLYLQLMSGKIGLRGCLSTWKKPEKTVSPMSHVSRPLLLPYHPFSPASLTDACLFASPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTN6</accession>
    <name>A0ABR1UTN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014387</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660889.1">
        <property type="nucleotide sequence ID" value="XM_066818701.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051761"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17324">
        <property type="entry name" value="MFS_NepI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910">
        <property type="entry name" value="TRANSPORTER SCO4007-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="83"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="482"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="534" mass="58028" checksum="1C393C0EEF3EB009" modified="2025-10-08" version="1">MGKEKKPRTEESHAHRDHMGLSGVTEEEAKDAITSQSQDRRPSGSSIANTSENGTSKRSIWTLIDFWKPQRCRYDPGNPPQFTLATNILLGFAGTFTVANLYYPQPILNLIAKEFDVSYERSSLVATLSQGGYAVGLLLVCPLGDKVPRRPFVLLLVFLTATVWLGLCLTKSFHVFITLSFICGVGTVTPQIMLPLVGDLAPPEKRAASLSVVVSGLAMGLLIARVLSGIVANYTAWRNIYWLAFGAQYTVLILLFLFLPDYPAKDAKLPYFRLLSDIAKMVVTEPLLLQACLSGFLLSAAFTSFWTTLTFLLASPPYSYSSLEIGLFAFIGIAVIALGPLWSRLITDRFVPLFSVVLGLSFEFAGLLVGTFIGSFSIAGPIVQAIMMDTGANFAHTANRSNVYNLDPKARNRVNTAYMVFCFAGQLTGTAVGNRLYAHGGWVWSGGCNIAFIGTAILICFARGPRESGWLGWRGGWNIRRDIKPTPNSGAQPPSHGSDTETAVEAAGSSQEEDVPVGGSHDATKRKWANMTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTT4</accession>
    <name>A0ABR1UTT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-hydroxyisobutyrate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660906.1">
        <property type="nucleotide sequence ID" value="XM_066818718.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051778"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43060">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43060:SF17">
        <property type="entry name" value="L-THREONATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="1">
        <location>
            <begin position="7"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="2">
        <location>
            <begin position="176"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="2">
        <location>
            <begin position="321"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="46042" checksum="B5431887BAC9F6B3" modified="2025-10-08" version="1">MASSKPDIAFIGLGAMGFGMATNLVKQGYKVTGFDVWGPTLERFKAEGGLAATTPAEAVKNKDYCVCMVATAQQAQAVLLDGENAAVPALPQGAAVLLCSTVPCSYVQELEKQLSAVGRGDIQLVDAPVSGGAYRAADGTLSIMAGASDAAIEKSRFLLQEMSDPTKLYIAAGGIGAGSNMKMVHQVLAANQILATSEALGFAAHLGLDLKKAADTVISSQGKSWMFEHRSPRALHPEFQPIASATTIILKDTSIITAEARRAGFPTPMTSTAEQVYFTGVGRGYGPDDDSSLIRLYWEGKGKVGPVAGTAQTDEAKLALVVGLLKGIHLCSAGECIAFAARLGLDLDQVFELCINAAGGSAMLEAVGPEMMSLVKTAGGAAAGSAAGDSLDKVVSELQEAVDEAQRLKAPVFLGSQALNLTRLALAHRPKTAAAATTGVVVKVWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUE3</accession>
    <name>A0ABR1UUE3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_014646</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661148.1">
        <property type="nucleotide sequence ID" value="XM_066818960.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052020"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF187">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8062549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="435" mass="49709" checksum="4759D848A6E73912" modified="2025-10-08" version="1">MSAITEQLGPVLNQESLFCLGGALSGVSLHHGVFIRGEWHNQAPIIFRIYAAIFGFVATTRIFYRTADPADRQASCLVLASFFHVLGMFASILIYRRFFHRLNKANFPGPRWASNRILYPKHFTDKQRPGPSEVTVFLPEAHEVLGGRQSECIKSEFYDLLWPERALFAARDKAVHAKRRKDWQYGFSPGAMEHHERKVLQWVDELDRQLATKAKDRSTVNATDYFLWFTFDIMGSFTFSKSFNMLERQRWHHIVLKTQNARSLLGPLTGTPWLLHIGVKIMPRILWVRDWYESVEWCQAQMLERLETGSLPGVPDLTSFFMRNKNGKSDPWLAGDSLLAILAGSCHSRGDASSSKPFDGGSRKTMDNGVNIGDYYIPPHTTVITPHYTIARREDCFVEGTKFIPERWTTRPQMVLNPAAHIPFSIGKIILIVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUJ5</accession>
    <name>A0ABR1UUJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014686</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661188.1">
        <property type="nucleotide sequence ID" value="XM_066819000.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052060"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="40"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="393" mass="45646" checksum="799CD2763BF42B11" modified="2025-10-08" version="1">MLGRLRMSVRQALAAYTEFGNQVFGKSRYWHINSALWYPRSKYASSPMEKVFSELISRQLDIRDPGEATDETFESSEDQTRTIVFSWRQSRSVSKPYLWRSYHHRSRMGGQDNKFHLNLGPAANIPIYEVARATSAAPRYFEPIVINRWTHVDGALGANNPSPQTINEVYSKENERVPALSVSIGTGVNLQDQDEGTDFSERMQQVLQSRKSNKLRRRQILGKQWELLTGVARQTTDTEAAVVNWERDCKLFQRAGFPNQEDFEPWWHRLNVDNTLKAIPLDDWTPRKGGKETLQQITNLTSEYLAKQHVQDTIARIAQVLVDKRRRRVWTEKWEHFVMKVAYRCPKSKGHTEQFNSREDLRTHLQAKHDHATLTEAEMHKLLNKARVVPSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV23</accession>
    <name>A0ABR1UV23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_014639</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661141.1">
        <property type="nucleotide sequence ID" value="XM_066818953.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052013"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF14">
        <property type="entry name" value="PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="9">
        <location>
            <begin position="283"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="114"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="468"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8062542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="477" mass="52791" checksum="8C2185C52F77B455" modified="2025-10-08" version="1">MFRAIVDYNQISDSYTDADGLPFRKEELNPREVREIFGTHIPAADANRLLRIVHGRRVAGTLDDPDLQQNTAEYSPSDKVVALEYLRKHIPMDEIVNAGLRAEDELRLLEEQEQYDEAAQPEHESEKPVAKPEYPTQPPIGKLPRKPKSDSPYGESTIDRIRARNLAAQATEEKRLEEERVKREEEEQLGNIGVLSTQNAQPRQMSPWRQKHAMRATSDLEAPPGKSIWERLMPAFAMSALVLFAAYLATQMYKPPSRSQRLWPDIPPAAATCLGLILANLALVGAIFSHQALGHMIPNLVALWFFGVRLHDEIGRGNFLALYFASGTLGFLASLSTLVITGTLHATTLGASGAIYGIMAAYFWMHKNDEFKIFGYPPAPMKGPEGVIFLGLLVGLHLSGLFSKKAKVYDLPSHMGGMFAGTLGIDLIRRQMDDRARIRAEKLKTMGMLDKALEQKTGSKPVADDAPSSPPSPSAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWA0</accession>
    <name>A0ABR1UWA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660929.1">
        <property type="nucleotide sequence ID" value="XM_066818741.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051801"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20265">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045296">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052000">
        <property type="entry name" value="ETFRF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024:SF0">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024">
        <property type="entry name" value="GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="70" mass="8196" checksum="B17CD68BC7CDE393" modified="2025-10-08" version="1">MSAPNPALRREVIAIYKELLYLGRDYPQGYSWFRPRLHRAFMASADLRDEEAIRKGIARAEFVKKEIEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWB7</accession>
    <name>A0ABR1UWB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-terminal amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660960.1">
        <property type="nucleotide sequence ID" value="XM_066818772.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051832"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07566">
        <property type="entry name" value="ScNTA1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039703">
        <property type="entry name" value="Nta1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11750">
        <property type="entry name" value="PROTEIN N-TERMINAL AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11750:SF26">
        <property type="entry name" value="PROTEIN N-TERMINAL AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="352"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="831"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="877"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1080" mass="118850" checksum="FFDBAB0ECA33026C" modified="2025-10-08" version="1">MRIACLQFAPQVGDIDNNLNRADAVLSKANPEDLDLLVLPELAFTGYNFKSLQHITPYLEPKGSGISALWARTTALKHNCVVTVGYPEKVDVKPKWPTSPEYYNSCIIINGEGETVGNYRKNFLYYTDESWALEGQEGFYEGYIPGLGHTSMGICMDINPYKFEAPWHAFEFAFHVLEMESNLVIMTMAWLTREDGRMFSRMPKEPDMDTLTYWITRLEPLIRDENDEEIIIVFCNRTGIEDDAVYAGTSAVIGIKDGEVRVYGMLGRGDKELLVVDTDVEPFAKLVYRPEDGSAVASVNGDSKRPTRTTTPQPGFPEAGQEPIPEPRQEHRQEHRSESRQESRREHRQEYSSGKSTKSHSSGSSESGRTEKTSSSKRSTSSKRTESRIGRTHRTDPGADHQDVPSNSVREYEHVPVGSRSRAGSVRSTLSAHGSVSSKGSKQSKHSQESQRSKSSSRTRDSKGSSDSKDRKHSSSTRPSSRKQERPLPKIQIPPPPLPGNNNAIPTPTGPSPTPQALRPKLIIPSDAHKRPAVPHVPTPHPSAGAYKSRDTRIYGGHVSIQQHHNDIMTPTTAFEDASPMSPRFFWIPSDSMLKTPLDSRMWTPALADSPILKNYTPVVSRSAVQSRSAMHRREPSTTSQHPAERPATGPPEKSGSKPDDSQMQKGDENSRSENDARPDRPASPKSRNASRTRQLDRSDSAMGNHADLAAIAQRLEALSPRPDSAASQRINAPSPRPGSSMGHHVTGEGAQEAFPERPSAPKSRNASRTRVVSPVDPVGKERQSSVSRASIPIAASPGIEMQQLHRGPTALTYRPDVRMTNIEAAFRSASRPTHSRSNSISTADLRAITGNSTGVVRPQSRAASRGRQRAPKEPLYTNQDGAAEAQSSPRDTSIPARRPSAPSYGFRSPAEYEEVRRISPEYQNSGGVEDENEIVQEIVIRSCPNCPTHGHMHRNTPQLQQEQQHIATQYAPATGETGKSPEPTAPADASFNKEYKESMSILSHYSSSVETLASTKTSPATPAFDPKAPKAMVFVRNDDDTIPTTPLSAPFLNQALKSPKALERELMGKGIDRPKSAVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UY37</accession>
    <name>A0ABR1UY37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_015058</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661560.1">
        <property type="nucleotide sequence ID" value="XM_066819372.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052432"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="893"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="936"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1011"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1035"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1118"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="272"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="605"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="897"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="571"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1405"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="828"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1413"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1434"/>
            <end position="1443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8062961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1453" mass="160211" checksum="92FF1A5F0350550A" modified="2025-10-08" version="1">METTREIFESICGDDSFGPSVRSPECRGGGFDFTLLFEESILTTLPAALFIALAAIRSFSLVGKRPAVAICIYTGLQVALLVLATKTGLRTKATLASAVLSLVTGLSLAVLSHLEHAKSIRPSFIINTYLIATIIFDIARVRTQWLSKRSGNAIAGVLTASLTIKCAMAVLESIEKQSLLLEPDHHYSLESTSGVVSRSWFWWLNSLLFAGFRKVLSLEDLPSISEKVNSERLSHRIQATWNNCNRKRKHALVLACVWSLRWEILLTLVPKFLVVGLMVSQTFLIQDAVHYIQGDPNDGDNNGYGLIGAFAFVYIGFAFTTGWFTHLTIRTMSMMRGQLISLIYLKTTTLPVTSVNESAATTLMSTDAQRISETFQLLLIDTLPLLAQLGLAVYVLYLQLGAVCVAPIIVAIISVSLSTVLASRIGPRQKNWLEATQKRINYTTEILGAMRNVKMLGLAKQMEHNIQNMREKEITVSRRYRRLHALNITLVNMPSIFAGLSLFATYAIVSRINGTEGMSVSQAITSLAAMMVLAQPLIMILYAIPVGWSALSCFTRIQEFLNEESRVDSRSLLSMDSPPDSPREKEPIQRVSRISSGSHARGSSIRVEKADFAWSSSDDAVVKGLQTHIGPDCHLTIIVGPVGCGKSTLLKGLLSETSKTDGVVSVCTPEIAYCDQTAWIINGSIRENIIGRSEFDESWYQPIIQATALEVDLRQLPNGDSTIVGSKGLKLSGGQKARVSIARAVYARKPLAILDDVLSGLDAVTEEHVFRGVFGREGLFRKSGTTVVLATHSVKRLPDANQILALNENGEIVEQGAFSQLNVPGSYIHTLQVKLRKEENEHEEADEAEYDPIDEKTKEIVKVEKKAEAEVDESRQVGDWKIYRYYGHALGPMALFIWMFLLSGGQTFVGLGQIWINWWAEDNDNGGPDRTGYWLGIYAMFNSLEAILTMMAVGFLWIVIVPRSGNHLHQAMITAAMKAPLSIFSETETGVLVNRFTQDIRLADMVLPQSMVNVVFHSAGMLIVVAVAINAVPWITIIFPPIIVVLYFVQRFYLRTSRQLRLLEIEANAPLLSHFIESLNGLVTIRSYGWVGDYVARNMELLDQSQTPSYHLQCIQRWLVFVLDMIVAGLVIIIMGLTVALRTKVNPGYLGVALVQLMTLSHELTGIVQYWTMLETSIGAISRIKDFAEKTPDESAPEETDAPTADWPSRGAFKFENVFATYGYEVLADISCATYDADLLCFNSNGKPAVLKDVSFTIKAGEKVGIVGRTGSGKSSTTLAILRMIDIEAGKLTLDNVDLTTVKGSVVRERIICLTQEPFIYPGTIRANIDPLRQSNDEAIASALQKVGLWTVLQSKKAAAAAKKTTTTTTETDAATHTEVLDTAMDTDFLSHGQRQLFCLARAAQAGPGAHPGRADEQRRQPDRRADAAGYPRRVPRPHRHHDRAPAVVPRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UY94</accession>
    <name>A0ABR1UY94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_015132</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661634.1">
        <property type="nucleotide sequence ID" value="XM_066819446.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052506"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8063035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="353" mass="40168" checksum="3638FC414893821F" modified="2025-10-08" version="1">MQNEDTLTVCWLDHCWRRGNGFKFEHELTEHLQQQHQGATLEENNVAEPRRRRQGHQESAGGEGGINYQETVGKDVNMKLIRDLELRLASLELERQHLRHQIMEERDGHQIEIEDPRKCNKSEASSDIEHVGRFTAMAQPNPPGHASSSNAGSGNQYVCQTCNKVMSSETNLWRHNKTHDKTEVCDICGKAFAKPGQLGAHQFRVHKINKSDFGRLAIHLDKVHQGATTVDNDQAAADSAIKLTGESWSEDESDEEKEEESEADEDGLPTADKGDHSAKEQSDEDTAANGEQQRLSPRNYERQYRVIKRTMAKERLRHRKEFIAIYNSHGEAIQDLEYRVAQLEQLLSSRSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1T0</accession>
    <name>A0ABR1V1T0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661898.1">
        <property type="nucleotide sequence ID" value="XM_066816206.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049266"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="484" mass="52088" checksum="9C95C84CD791158C" modified="2025-10-08" version="1">MPHSPTAARASRSSTSADKPLPPIPEQRGGAAADDIELRQQQRRPEDRNRISSTHHQPRASPIALPWETSRLAKHELTDMYNEVHRTMGHIPYVVSGVGALIDHGFTGRTANKVTIIVPEDSRGVVRAWAAASGSHDVGAGSDSVAIRMPKDGSLRRVRVRWVSTAAFGDLEIVGSSSSNARVLGLASQIDQISTAWLQYRERLAAPGLTTQKERERLERELQTMVGDIFWCLPPRGRDAHRAEAGVLEAVPQREGLDPFTHAHDDARVEAQRAGVDVAAVLAGHRQRGEVRAHDELLRQYGIEDAGLMGGAGGGGIIEEQPGPFEGMRGLGRENRKDNGLLSVYTVATTVCSEAAASSAALSDAPAPPMPPPKAAVSSSSKRQNVRELPAPSSRLRPGPAAGKREELARMRSSPGPGRMSMEERGGGSSSRRGELGRSLTTTGTGTSATRKPEKEVKPDRQSQHQARHSVEMVSGRGTPEHWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1X5</accession>
    <name>A0ABR1V1X5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arsenate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011937</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661944.1">
        <property type="nucleotide sequence ID" value="XM_066816252.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049312"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053065">
        <property type="entry name" value="Archenteron_Induction-Rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024382">
        <property type="entry name" value="Vps3844_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853:SF1">
        <property type="entry name" value="DUF3844 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12955">
        <property type="entry name" value="Vps3844_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047089436" evidence="3">
        <location>
            <begin position="23"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar sorting protein Vps3844 C-terminal" evidence="4">
        <location>
            <begin position="282"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="393" mass="41872" checksum="A71840D9668D290A" modified="2025-10-08" version="1">MKFTSFLAPAFAGLAVAETAASQPSTEAYILRESRPASSSKDASSSPSISANAAQAILSDRLSANDKLAQDISEADYDVMNRFGKPAAKLFGDDDASASHQLVILYKGVDAENTQALKKALNGASPSFTSASALNYFPSAKSYNTKKCKFEDAIDPAKDACWSGVSRTAQYLEIDLSKDSKSTSALSKNMKKLQSLAQSGKMETLILIHPSAQAASANPQELRRRDHKSEVVLTDKETAKPTKPADANKAKASTSPATSHPFNDKDKDGNKKKKHNGLYPSCFASQDACNTATGNCTGHGVCENKWSEGSEKKCFSCRCLATTEKQADGRPSLYHWGGGACQKRDVSTPFWLLAGFTIIMISIVGFCINLLFQVGEEPLPGVIGAGVSRGGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2I5</accession>
    <name>A0ABR1V2I5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012147</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662153.1">
        <property type="nucleotide sequence ID" value="XM_066816461.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049521"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="57462" checksum="94F2C22E9E437A60" modified="2025-10-08" version="1">MWALSFEAISPTAIIEIRSILALVVPTLLVVLVCRRYWALRDVPGPSLAAFTRLWHARTIKNGTHARDITALHRRLGHFVRIAPDEVSVAHPDGPRKLLLEALRKGYWYETLTFPDSTYKTPMATVDQKEKIERSRLLASAYTTSSLLQSEQAINAQAELLLKWMDEHAVSSKPTALSKFFTFIAYDIMGEVIFSKSFGFLEKGGDIEDSLRQGLDFGAYVAVLPYFPWLQKLLVNPLFASFFQLVMPSNYVVDRSIRALEQRKKNPDARFDYVAHWLRTHEKHPDRLTAKDVQAAATSNVSAGADTVTCALQSFIYHTIRHPNAWRRLQDEIEEAEAEQRQQIGESSQDHPVFSFAVAQKLPYLQACIKECMRVCPPSTIGLQRVAPRGGITIGDRTFESGTVLSVHLPSILLSEELWGPDAHEFVPERWLGDDKKTAALDKYFIPFGLGYNSCVGQNLVRIELSKILPTIVRRYDISLVNPEQEWTYKTYVAAVPGDWPVYIKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2S6</accession>
    <name>A0ABR1V2S6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662243.1">
        <property type="nucleotide sequence ID" value="XM_066816551.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049611"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045790606" evidence="1">
        <location>
            <begin position="22"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="200" mass="21363" checksum="94D5ABD4F1715A24" modified="2025-10-08" version="1">MKFSPVAVTGLMAFLSAPATAAPAPGSEPAPVDFYKASGMTEMKDGLYRLAYDADGAPRIHFTPPSAAALAIRGANTTTNTNANSTAAAVAGGISLSERSEGCDNFRLDGQDTDAANADLQAACGDGYEGTVWSQSGDTVAFYCQYASAPRCRARESRNANYWITKKCGRYWAGSYESQGRKYAYGYTDPKRHNFCGIWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V351</accession>
    <name>A0ABR1V351_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662363.1">
        <property type="nucleotide sequence ID" value="XM_066816671.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049731"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="25564" checksum="085FFB2AB4491C90" modified="2025-10-08" version="1">MAKERAAKPVKEKKQKKEVKVSGDKVQKSKKEKRTVPLESEDVDMDSDSSTAQKAASKKNKKGPAALKKSKSSKAERKAAKAVAKEDESSSSSSSDSDSDSNSDSDAVPSTSYKLQPVATTTTKVKKTPVAVEENALFAVDVKPAPGCQEGCCCGRTIRCREEEVEAAMSEWTRKYDDKAAIREEKKAQRKQKESARLRNKRGKLLAGRALKERTKQLVKMEKKAKKKAAKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V395</accession>
    <name>A0ABR1V395_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012402</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662408.1">
        <property type="nucleotide sequence ID" value="XM_066816716.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049776"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337:SF3">
        <property type="entry name" value="PURINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="XANTHINE/URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="562"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="563"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="575"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="601" mass="64736" checksum="73B41FF71BCEF93F" modified="2025-10-08" version="1">MGLQGLFQKAVDKTVVWEDRINRSTFGRVFRLDGSGHPKQIPGASFYREIRAGFATFATMAYIIAVNSTILADSGGTCICTAPTRPDGIKCDGDASYDACLNVLKQDLVTSTAALSGLASIAFGFLTNLPVALGPGMGLNAYFTYQVVGIHGSGMVPYRIALTAVFVEGFIFLILALTGMRQWLVKMIPATIKTACGVGIGLFLTEIGLSYSAGLGAITGGLTTPVAIGGCPANRLDNHGECQDSVMSNPSMWIGIFVGGIFVAFLMAFKVKSAIVIGITLVSVISWPRDTTFSYFPDTDAGNDRLEFFKPIVAFHPIQKILNAQQWNLEGASTTQFILALVTFLYVDIIDCTATLYSMAKFCGVVEDDGDFPRSTIAYCTDAVCISIGSLFGCSPVTAFIESGAGIAEGGRTGLTAMTVGFCFLISLFFAPVLASVPPWATGPTLVLVGCLMIRQVTNINWAYIGDAVPSFVTLAFMPFSYSVAYGLIAGMLIYITLNTMIWFVVHFSDGKIVPSNWDQKEVYHWSMGKKDVPKWMLFIRNKIGGKGRRGEEHKVAVELVDNDSGGRSSSRNGSTEDKDAVVHPHYDGRPISEQELRTGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3Q0</accession>
    <name>A0ABR1V3Q0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662574.1">
        <property type="nucleotide sequence ID" value="XM_066816882.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049942"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="257" mass="28831" checksum="BCC0AE066D641BFF" modified="2025-10-08" version="1">MPPYEIRGCTVADAPGLAYNNIGAFWESPGYKLLWTDRTLEYVTANAAKRMPRNLLNDRAQRRHQLVVDGETGRIVGYARWILPHRLVGEWLEAQTPAVSAEEEQEFTKAFDKADWSFLDLPGMDDHVHVAKAKYFERNNECIELDYLAVHPDNKGRGIASMLVGHGVAAAERMNVDIYMMAYEAGLQVYKKFGFQILESNVQDLAKWGGTGPYATYMIEKKIAKRGSQGATFHSRVVLSAHVGKGFLVGVSTTNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4B5</accession>
    <name>A0ABR1V4B5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662505.1">
        <property type="nucleotide sequence ID" value="XM_066816813.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049873"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="503" mass="55868" checksum="D72E76F9FA73AC51" modified="2025-10-08" version="1">MDPLAVLPPEVVHGTSSSNTPTARSSTPPPTKVDRPDGCRDLAFLREKRSLTDYFQGVESWRDLCKRQAKVRRNWLSDQPAVRGRTYKIGGDPVWRFRMDFKRRFIVDVRPFAHLEYDMERGVAAWDRFGNSIEVWQANDEDEGSRGVFSRVAVLHHECETRGYQLSYDTLCVVSSDGEGFVYDLRPGKGEGDNDKLSPRLRTHIDIERGAVGHLDQGEGAVMYSMARKGYHFHDKTTGEALGRLQPAACTNVFHIKQPLYNDDEDDAESFVLESVAVLERRARGSNRVISLPGGGSHFVPLRAEKGRHPNHGELHVSEIPLEQDEWGAGMLSGSFMVGVSRAGRIFLCSDWPALLADPESAAASNCTAIIETVSEGDSDRFDMGGWLSIRNGRILFEVDGRIYILTVPTEPGAHLPSFLSESSSGFAVASSPGLGLSRPVSFMAVWDDCISFTYCTIGWAVELDRLVPMPVKAVRVLSWSPCLDGQKDILCDSEENRVSIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4M5</accession>
    <name>A0ABR1V4M5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662904.1">
        <property type="nucleotide sequence ID" value="XM_066817212.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050272"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="178" mass="19441" checksum="F5CAC02390974DE5" modified="2025-10-08" version="1">MAFNNQNNDASTSPTGSMSMSDNMYNSHHSQLLSSSISSLSSPTTAARQSSSHISKTYRQSSQLFLTRRMPEALSTILPLVTPPTPGLGESAETVAENEPAPVAQASRSTRIKVWSLYLTILNGILELEPDEGKDSFGTQEYRALCHKVREGDIWEEVVRNGYHGIEGNVDADVVINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V500</accession>
    <name>A0ABR1V500_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U3 small nucleolar RNA-associated protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013027</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UTP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663033.1">
        <property type="nucleotide sequence ID" value="XM_066817341.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050401"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013949">
        <property type="entry name" value="Utp6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055347">
        <property type="entry name" value="UTP6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08640">
        <property type="entry name" value="U3_assoc_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 6 N-terminal" evidence="7">
        <location>
            <begin position="12"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="400" mass="45343" checksum="F6F5A8AEC4F69A96" modified="2025-10-08" version="1">MAAIADKARYYLEQSVPQLRDFEAKNIFSQAEIRNLVRKREDFEHKVLSPGCKPADYLAYVAWERSLEKLRAKRCARLRISQSTSHAGEGRVFGILERSIARHPGSLELWKEYLMFAKDVKATKRWRRVITRALRMHPAKSELWVLAGKRAADNNDMSAARNFFMRGARFCTKDSMVWIEYARCEMQWLEKMEARKNKKGGVNRAIAEQAENDDDQMLFDEEDSEDDADENGRLMVPNPDGQAKKVFDNSTAEKLEEGNPALDGAIPMAIFDIAKKQPFFNAAAGEQFFDVFGEFPQVSSQPQIVQHVLDTMSELYPHNPAACNCFIRQPVLGVSIDSAAYPQALRETLSRLKSSLTSTGDKIQLARKTLAWMNPVLASESLDPGLRTVLEYTAQTLPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5Z1</accession>
    <name>A0ABR1V5Z1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_012150</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662156.1">
        <property type="nucleotide sequence ID" value="XM_066816464.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049524"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF26">
        <property type="entry name" value="MYO-INOSITOL TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G01560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="453"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="490"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="106"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="599"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8065403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="625" mass="71605" checksum="248BBFDFBA893CF8" modified="2025-10-08" version="1">MAEKRTDLEAPEPQVSHRNEASLGTLLNNPLTGMSREEVVADVVGFIQERGLTEHREDFIKGALVAQVTNQDYAFEQIKELREDEKDLLRREITHRWSQPFMLYFLCTLCAGSAIVQGMDQSAVNAAQDFYFKELNITRSEIQGLVNGAPYLCSALIGCWSNPVLNKYLGRRGTIFVSCAMSVITGFWMAAADSWYNLLVARFFLGFAVGAKSSTTPVYSAESTPKTIRGALTMMWQMWTAFGIALGTIMGVAFSKVTIFGEETQWRWIMASTSVPPLVVMLQVYFCPESPRWYMEKGQYTKAFDAISRLRFSRVQAARDMYYAHKLLQIEESQRAGRSWKDFFTVRRNRRAAQSSWFVMFMQQFCGVNVIVYYSMDMFQRAKYTRDEALLFTMGTGLVNWIFAIPAIYTIDTFGRRNLLLVTYPLMAIFMYWTGFSFLIPDNDPESPSQFKLAMVATGLFVFMACYSPGSGPVPFTYSAEAFPLHIRDIGMCSATAVTWGFNFIISFSWLPLVDAFGDTGAFCYYGTWNLIGWVFCYFFLPETKNLTLEELDKVFEVRNRDHAAYYLKKLPWYFRKFILFQDVEPMPPLYQMDQTVAPPVQEKSRDLSDKGEATQMENMYDKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V635</accession>
    <name>A0ABR1V635_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663398.1">
        <property type="nucleotide sequence ID" value="XM_066817706.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050766"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="104" mass="11596" checksum="3519F704FD0E4CF8" modified="2025-10-08" version="1">MTLAAQVGCRFVGGRERVGFPWPGAERGGRRRCDHGRVAGSGGGVESASSVAGRLDGDERVRIRNEGRERRVRLLLAGRRVMEATQMLCCYIISRLSLYDWCWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6C0</accession>
    <name>A0ABR1V6C0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663501.1">
        <property type="nucleotide sequence ID" value="XM_066817809.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050869"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046488">
        <property type="entry name" value="Sfc3/Tfc3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044210">
        <property type="entry name" value="Tfc3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007309">
        <property type="entry name" value="TFIIIC_Bblock-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04182">
        <property type="entry name" value="B-block_TFIIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20222">
        <property type="entry name" value="DUF6581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="854"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="133"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="395"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="625"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="759"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1027"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1342"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1450"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1676"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="638"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="650"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="689"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="858"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1058"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1352"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1371"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1459"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1690"/>
            <end position="1700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2158" mass="236978" checksum="BE1B10CC6444FC3D" modified="2025-10-08" version="1">MDRGLDDLVEWLLTEIGFSGLQGRLTCFACHIPIVLTCRPLGFSPLHLVKAVKTFYTQTNIETETSGADTQLPLPSSEVVNSQEVGESDIVQASVVWNWLTARNDVIVGDDNRYKGISLKEALDISGYVPSGNLGQTSAGENETPKPAAQGSSAGNEGAGTDSRRPGKAVSKITPRLHLSEERLWKAITGHQPDLKKVPQFEWQALVAIASVREVGILQGDLVRLTNQDKRSLPTRTDALARKGYIVKQPVMLRGCRTSKIWLAQFAHHAKQETINEGLASAKVDLTRETLTKDWEPVPFSHFWNGARVDHIALAQGFLAIVKAFGKIRYCDIRIKLDIVGKTSQMRAMGKSSRWFTHRGIVEFRPMKAPDSNRVFKDCVEFIRDPTAEEWQAFRKTPTTRMRLKDPPSRRKDKSAASLHDSAKTGSKLSRSAQNELKTQQALIAKLPSPAMIRLSAWNPYKPLINTVFDIIKRSGTEGTSNLNIGYFLLGWPYRKWIFSMTTLLGQQRVHPEHLKPFSVTAQLARRGKTMTYSFFATSNIKPENGNAKLPLDGEQQETAENATTSDAPPTDLNIKYGFSRPSAKVFLRNSSAKYVSMPKKQELIPPIEPSEPNTPDTLVIHRTRRPKRSQPGHGEENSASEQLSETPTKRKRLLRGRKSSTPSLIGQVEETQPEPMDIDGPQPAETASAVPSSSQVVPESMPPPPLPSGVFYGLPNSLGPQKTKGRKRKSLVLVFRHPSLKKSSETGQQNVAHNNTLDTSSEQVQPMPSCGAEDPAAAEKNPVAESTSIGTEHPTAPIPESAPETVLPARQEDASTPAEGPGPNVSADQEDVSTPAEGAAPRNKGSKRGDKRFTCETCGNSWKNTNGLEYHKKKSQSTCNPTWVPPPPSLEILSVRRAKPKERSLPKMLTTPSKSPKVDQERSQLVLPTKRPNRARPETPQETPPVKGSQSSQSTVLLSVGQIHNGPGLSAAGKRVLPGANESFRGTEQLSHVHTSVSQPSVAKASPLVPETDIGAVLQGSNARPVSGVASAGATSTPTPVLDLPDRATPEHPLSTPKHSVTPQAQALQKTPSNSSNIGGTVPAPAAQRDTKQRSSKATTAQRRIRTTSLIEELLRENGGAFPGDHALHVVISSIWPRRFNDDVDPPDQRTCDIIVKKMIGAKVIRQDHYGFRDYQGNVKSISVISKASDGQGEEALTEKILGIKAKSIELYPDPYIPPGLSMLGGPNQAEALGIGETGSIPTAFTSIAKGSIRKSVLTLDYHMPVEASTLPRGYPRRIDSRRLIPPREHTRRDVQDSFSHALLQEPGLSLRPEFTSYPYPMATNVGAGQLADHQTDGMEIDATDNAPGRGRGRGRGRGVGRGRGRGRGRGNTTGRGRGAGQGLGRGRGRGGKRVNVALDDDYFARQANAARYTWASESDLSVLWNLDADLPNVQRAIQLSESTRVLYPQPSDFTEMQQDDSDDDDEDRFLAEIPPQGDDVLSDKSDTAEACSNASPNFTIRFAPARRIEALGDGSWPAELPKGPRPGGVGESFAMIGRFPTSQWFLKENLPQNAQEMISMAPDASQRPSQARGLKEPSYEDFVQNLMGIEAWELSSEGVYLQFSGTAAPEYKFISLGVGETHTSTLVTSKLEWQKDLQYTAANLPQDILEAPFDDEICIPQRVGSLAAGELMAQSAPPPTHSRKMLSSKGQWKTPSGRWNQRSEAAAEVGLFDGEHHLLVAFLVLKALVGGVEKIVDWGMLIRLFPQMSLSGLRRFWSKMGKERKSFIDAFNARFPAAFLEAYEQGKLPPMDYDSLGAYDWKTLINWAAKLKTHQQVELPPRREVLEDRYSLQEPPEIEARWRDEWFGPITSAYARIDGSGGEPLTVPLGSDSDDDIIMKLAISWIKALCNSKSRCTVGEDVRDGLAKLGRANMDKKSLNTLLERAVSSLMHDRVISRVKGKFMGQVFKLNNNFERRAEKLANMENGETMLVPLDANAGTIMAIINLQAQGRIVLQHENFPDVPFGFEPSNYEGRMFPKSYYSFDVRLTPSDKYLYSEDIPMAIEANHLPVPEKGPVGELPIWRDFFGNLEAGRWVQYVCLVVFALATKGPLNAKSAATLLHPMVEIFEVNLIVQWIQSLGILELTAGNHGWTVGEWWWLIIGNMVDLKGKGAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V725</accession>
    <name>A0ABR1V725_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 17">Mevalonate kinase</fullName>
            <shortName evidence="17">MK</shortName>
            <ecNumber evidence="3 17">2.7.1.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PG997_013751</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17065"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:58146"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.36"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:17066"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="16 17">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.36" evidence="3 17"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663757.1">
        <property type="nucleotide sequence ID" value="XM_066818065.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051125"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006205">
        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290:SF2">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 17" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 17 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 17" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 17" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="14 17" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="11 17" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="13 17" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="18">
        <location>
            <begin position="180"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="19">
        <location>
            <begin position="354"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU363087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK8067004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="503" mass="55145" checksum="A5BF5A783E7EA0DE" modified="2025-10-08" version="1">MSNGTNGTIGLHESIDKLRLNGHFSGNGVGVGINPTNDPVRIKMARKQSSPMMPAFMVSAPGKVIVFGEHAVVHGKAAVAASISLRSYLLVTTLSKSRRTLILRFPDIDLSHEWNIDELPWDAFQHPSKKKYYYDLVTALDDDLLAALRPHLAKISPEKSESERKVHQNAALAFLYLFLSLGQPKFPGCMYTLRSTIPIGAGLGSSASIAVCISGALLLQLRTLSGPHPDQPPEEARLQVERVNRWAFVFEMCIHGNPSGVDNTCSTQGKGVVFQRPDYQQPSLVKPLWDFPELPLLLVNTRQAKSTAVEVGKVQKLKDTHPNLVGSILDAIDKVTHSANEVIEGDGFDSQDEESLRRIGELMTINHGLLNSLGVSHPRLERIRELVDHEGIGWTKLTGAGGGGCSITLMRPGVPQEKLQRLYERLEEEGYEKFSTTLGGDGIGVLWPAVLKNGLDEDEEGGMEINLDKFLSAEGNDGVEKLVGVHSGGAEREGWKFWRVESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8T3</accession>
    <name>A0ABR1V8T3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013427</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663433.1">
        <property type="nucleotide sequence ID" value="XM_066817741.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050801"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="36357" checksum="915E3ADDBBF61911" modified="2025-10-08" version="1">MGTTADLGLPQAESNGTPAVGKGHLTIKERLLQLNGVFPMDDAVIEALPGGSTFVSAEHFSKSAFTITGKVTARNEKGAEQLYFLKVAFGDQGRTMLRGEYESSKIIYKFVDMDVITAPDPAEFTKRLAQLHKLSESPTGKFGFAVQTCDGQVAHTVDWNSSWADFYLKLLLGVCKKDLEANGPWPEMELATKQVADAVIPRLLGRLQENGRKLTPCIVHGDLWEGNMGINMRTGDSILFDAGSYFAHNEMELGHWRCEFSSVFRAEEYTRHYLRNYPPAAPASEFDDRNRLYSLKGAINYAAGHPGSTLRKTFVILTSRYESTADLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9S5</accession>
    <name>A0ABR1V9S5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA repair protein rhp7 treble clef domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013757</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663763.1">
        <property type="nucleotide sequence ID" value="XM_066818071.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051131"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056451">
        <property type="entry name" value="Znf_Tbcl_Rhp7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF247">
        <property type="entry name" value="GH16156P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23550">
        <property type="entry name" value="zf_Tbcl_Rhp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA repair protein rhp7 treble clef" evidence="2">
        <location>
            <begin position="148"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="588" mass="65431" checksum="9A8FD2953DB726EA" modified="2025-10-08" version="1">MTKQREFALCRESRSNRQQRAGRAIRGPHSALTDFLASQNISANRIREDAEARRNAANASNAQTASTDAGASSTAANGDADEIAEVEEAAQVATAADKATEKKRKAQAAAIEKIKKGKAFKKRKRQDEDSDSDGIAEAILAERAAPLPGQMENCEICDKRFTVTPYSRAGPNGGLLCNKCGKELAQDNKDEQKQKKKKVAARGTARRQVASNRLDGVIGCKSLMAMCIQTLVNNIDLADDLGDMPAQIVDRVARQVSKRRILTPMSLNLFLQSGYEDVTVYDAARLGSDDLIRIFQMVPKLKNLKLKNAIQFKDEVMDYLITRQTPLDSFYLHGANLVSEESWKKFFCLKIAHNQQVTDAGVEHIAKLNGLEHLSLQLITPTSTEPYVKVINSIGKPLRTLSLTGESLSDLDDRVLDAIHENCTSLRKLRITHSEVMTDAGFARLFKDWTNKPLTFIDFEKCRHIDSSKPRENAHLNGLCSDGFRALMCHSGKSLRHLNVHACRHIKREAFEDVFSLDKEYPELENLEISFCEEVTDFIVGCIFRTCPKLKNLNVFGCMKLKDVRVPKGKILVGMPNAMGMEIEGTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VA93</accession>
    <name>A0ABR1VA93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663717.1">
        <property type="nucleotide sequence ID" value="XM_066818025.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051085"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="65" mass="6955" checksum="D1A33A79C55A26C5" modified="2025-10-08" version="1" fragment="single">YIAPAPANPVRTNGSLKRGSDPPRNAACNPPFQWKNRQTSNPDRGVRGYTTKRAGRAAYAANNGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ36</accession>
    <name>A0ABR1VJ36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665057.1">
        <property type="nucleotide sequence ID" value="XM_066815767.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048827"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="471" mass="50688" checksum="FD71AB963CF162B6" modified="2025-10-08" version="1">MDPSDLPLPLTSRRPAYGIYFEPEPRYAKVSGIVVSVLASSACASFFLFRFAQVKSWRSLAWTTWILLAIYFDSYLFVMASAVLHFSFSLNEYHSLCEAATLLCLLAYLSSKYTVWGSGVPRYKSKPYLIHFAILTGALFACWIILIIFRFSRLENGLCIIGIQQSVMIGPLAVDVVCNAYLTAVFTFPIYRYTTKRPERAAPTVASSNTRSRNERLLRVAKKSFVGCILTLGSSIANLLALMLLDGEPAWLCLLCCKIDVLFNAVVLFWVTRTDSLDIAHSSRSKSDSARSRVTRLSFYTGWIRANMGQGPHPGRPFIIPQTPTSPLMGGGTDGNNSAERGGGGGGAGTSSVGHNNNNNNSSNSKGGDRRAVINATATTAAPAPAPAESSKAPTRSILKTAGTGTTDTVAAARSAYESSTEIWTGPDGHATEAAGLGISETRFDNDKEELGTDPQSETSGTTTSTSDTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ80</accession>
    <name>A0ABR1VJ80_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011499</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665104.1">
        <property type="nucleotide sequence ID" value="XM_066815814.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048874"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8071296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="51845" checksum="21B713B2FCD1E066" modified="2025-10-08" version="1">MEWPLGTSACSYLLSSVVTLLLVLITWRRYLSPISHIPGPLTASFTRLWHMYHILTGDQNTELIRLHKKYGIRYLLGLIAYHFDQAPWYKALALPDYRYQSAMSTTDPKQKMERSRRLAPAYALSNVIKSEPAIDETAGMFLSWLDEYAASQNPMDLDKFFSYLTFDVVGEITFSRHFGFLEQGKDVGNSISNSLALNAYIALAGYFRWLHVALLANPVVTWLSILPMGHLFNTTKRAVIERDESANARWDILASWFQQMRQYPDQMNMRTIHTQATGLVGAGSDTVSSALQSFVYHMVRHPTAWSRVRAEIDAAARAGRCRDRVVSFKDASELPLLQACIKEAIRVFSPVPMGLPRVAPEQGVTIGREAFPAGTILSVNPWVIHHAEELWGPDVSQFHPDRWLTGDVGKMEKYWVPFGAGYNACPGQHVAKIELSKVAATMARDYDICQVRKNQQWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJM2</accession>
    <name>A0ABR1VJM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Halotolerance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665145.1">
        <property type="nucleotide sequence ID" value="XM_066815855.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048915"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359">
        <property type="entry name" value="HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359:SF6">
        <property type="entry name" value="PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="4">
        <location>
            <begin position="34"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="281" mass="30403" checksum="7F9B769E1B6B1F2F" modified="2025-10-08" version="1">MLQYISSHHDAHHIRRESTSLANLTAALLDGKTHLLLAASGSVATIKLPLIVQALARHPNLSIRILLTPSASRFLAGQSVEQPTVSSLRHQPNVDAVYVDEDEWKEPWKRGNAILHIELRRWADLLVIAPLSANTMAKIVNGMADGILTSVVRAWDARGELDTDLAQLQQQQSQSDATATTNGATTNGSAPVKKTKRILVAPAMNTAMWRHPITAKQVRVLEDEYGVGNADGTGWFEVLAPQKKTLACGDVGDGAMMEWSEVVRAIEERLGLGGDGSAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJR0</accession>
    <name>A0ABR1VJR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphotyrosine protein phosphatase I domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011691</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665296.1">
        <property type="nucleotide sequence ID" value="XM_066816006.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049066"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16343">
        <property type="entry name" value="LMWPTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050438">
        <property type="entry name" value="LMW_PTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717:SF7">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="Phosphotyrosine protein phosphatases I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphotyrosine protein phosphatase I" evidence="4">
        <location>
            <begin position="5"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="170" mass="18753" checksum="559847B28F5395A4" modified="2025-10-08" version="1">MPEKISVLFVCLGNICRSTMAEGVFRSLTKEAPYKDLIGTVDSCGTGAYHAGDDPDDRTMATLAQHGITDYAHAARKVRPSDFDEFDYIFAMDRSNLSDLQRGYVKKNGSQKAKVMLFGEYAGGSTNKAEVVNDPYYGGNQGFKTAYEQCLRFSQNFLKEKLAEATEKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJU7</accession>
    <name>A0ABR1VJU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665298.1">
        <property type="nucleotide sequence ID" value="XM_066816008.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049068"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="9"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="314" mass="35805" checksum="17D5C850F9ED8533" modified="2025-10-08" version="1">MTVIEDVPGVEISIAVAGAPAKEYADPELEEVPNNHNSFLSSVYIECLDGQEFAFRYKVDSTYDWGYKDHELKFKFYIGGNLCDRRPHIKEMATRSGPFVGELKNQVEYNQSTKKWYKQKFVFTEVEKVDDADKKRVEEDKEIAKHLGVLKVEVWRVKVQIYDRQLPSKTGAPSSSYDQGITTIAEKALKGREISHGAGLDEGEPIEYKPSRNALGPREWVKYLKEDNGQMAIYLFHYRSKEALKKERIVARSPSPPLASGGDSEEEKKPVVKRERSCDAFGLDDEASVKSRRKRIKPEEDEEDLEVVDLTGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VK87</accession>
    <name>A0ABR1VK87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664162.1">
        <property type="nucleotide sequence ID" value="XM_066814872.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047932"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="84" mass="8887" checksum="E00A303B066FC326" modified="2025-10-08" version="1">MVKDVALVYFCTVCSGIQPSSPIRFGNGDPERPTVALFEGRQSAVVTFDYSGAAVVVEIGVIKVGIRGCGHGDKLVPEVTPQHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLD8</accession>
    <name>A0ABR1VLD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">High osmolarity sensitivity protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664853.1">
        <property type="nucleotide sequence ID" value="XM_066815563.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048623"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042332">
        <property type="entry name" value="Hsk3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013183">
        <property type="entry name" value="Hsk3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28289">
        <property type="entry name" value="DASH COMPLEX SUBUNIT HSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28289:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT HSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08227">
        <property type="entry name" value="DASH_Hsk3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="9646" checksum="FDE4EAE4FDA81C33" modified="2025-10-08" version="1">MASRNFNTGSGMTTRPSIAPQSSGNAVKARQLSHLHSQLEQLSSNLADTENLLRMTAVQAEAMRGLGSWHGGMFMAASKVLGEESVKDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU56</accession>
    <name>A0ABR1VU56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009446</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665723.1">
        <property type="nucleotide sequence ID" value="XM_066813761.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046821"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23952">
        <property type="entry name" value="Utp17_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053826">
        <property type="entry name" value="WDR75"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23869">
        <property type="entry name" value="Beta-prop_WDR75_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="349"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="600"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="868"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="877"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8074783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="945" mass="103349" checksum="F8D80CD76792F528" modified="2025-10-08" version="1">MAPIILEDETLAAIKRKREANDFGKSTPKKSKLKHKDVLRNGNSTVQTPAKAEAGTPARRKSKADKKLAEGPSTDAWKVSLPIGGRMLDIDAILTDDDQHLILAYSASIQVYNTADSLLLRKIPIKVTTKSNEDESIVAMRLSRTSPNMLWVASSAGRIWKIDWTTGSGSSACLKLECDLLADMEVDVTQVGSDTQDVLLVSVAMEDKWHVLACDVEGLQLKGTKTVVDRTSPIQNLRFLWGGQVLAASSGKDIIVGTLNSTPGSPFSELWYEVFIMDCSDDITCLDLRVAQRVHLTKQSQVEMGDQLVLDVVVGCARGGIFYYNDILPQLRLLHKAANITKSLQPRRLHWHRKAVHAVKWSRDGNYIISGGSESVLIQWQLDTNKKDPLPHLAGSIENIVVSSKGSSYVVHLDDNSTMVLSTAEMKPITYVSGIQTLVTPPPPSKDNIVTRVGNQRLRSEFMRIPATIDPAHPSHLLLGVANGQQIVDTGAPTSIPMLQTVEMSTVQGIAKQPLTRTHPTDVNITPKGQPLTEPRVTHLESSFDGKWLATVDEWLPPSGDVSVLDAASAERREVHLKFWMPGKEDSAFELVSRINGPHYTGRSEHILDLSADPSSHRFATLGEDGVVRFWQPVVRERDGLVIKNQAGRQLEQWTCLHTVHLHETKPSSTRSGALSFSLDGSTVACAFRNGADSAVYLIDTESGRVMDSMDGFSRGDIHAVRILSSQLIVLSDDLVVYNVVLDELSYGIRLSQDDGSAKSTLLIPQLAVDYASEKFAVAMSRPGKHGTIRSELATFGLDQSEPETLVKFSYPIVSLMTAPGSTGFVVLDAAAQLWSVSQRSQTGSVTLAQPLADIDLDKVEETAQPIDSKPLALFNDAEEASDDEMELDGPEEDADMSDAYPVVVPPQKLAELLDSAPVYAMPPVEDMFYEVAKLFSTKRNVNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUW2</accession>
    <name>A0ABR1VUW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA thioesterase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009708</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665985.1">
        <property type="nucleotide sequence ID" value="XM_066814023.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047083"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03444">
        <property type="entry name" value="Thioesterase_II_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03445">
        <property type="entry name" value="Thioesterase_II_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049450">
        <property type="entry name" value="ACOT8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066:SF34">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20789">
        <property type="entry name" value="4HBT_3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="3">
        <location>
            <begin position="45"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase-like C-terminal" evidence="4">
        <location>
            <begin position="159"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="346" mass="38380" checksum="A467D226E5DCC00A" modified="2025-10-08" version="1">MTEHRPTLVKPPPLDSTKAQIENALELTDLSVIGPDIFTNTRELWHPPGARGIYGGAVIAQTLAAAQRTVPADFVVHSYHCYFVLAGDSLTPILYHVERVREGRSFCTRTVQARQRGKAIFTVTMSFTKDGSGGAETVRHAAAMPEGVTAPPDDYDEEFGGAGGAGTSPFQTYRIEVTGQDGPAERKKTRHWVRARGRISEGGGHQAHLSALAYVSDSHFIGTVGRIHRLWRFPFPYEDLDKVPEHVRARTVALNEWEGQGPIEEMEGQPSIGMMVSLDHTIYFHNPKKVRADEWMFTEMESPWSGDGRGVVIQRLFSKDGTLLATCFQEGVVRIKQNEEAPRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV50</accession>
    <name>A0ABR1VV50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009791</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666068.1">
        <property type="nucleotide sequence ID" value="XM_066814106.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047166"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF49">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="502"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="610"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="248"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="727" mass="78295" checksum="C630CFC373E7C84D" modified="2025-10-08" version="1">MSTFEPINPGATRKKMAAPGQRGTEWPLRPLSSSNDQPGPDTDKAGQPSPACDDYRLPVDLDDPSLSPVPNHHGHHDSITDSDHFGSMHRHSRCFSTTTSERPLRQAESVYERPLSFNADEPEPQLDVPESAHGKDETKERSRFSLDNDRFSVLSDILLMYSPGLSRLASNNSQENRYLKNGERRLQVLTPISEQRHPGKIGARLSRNTIPWEPSLEENRDADRVDKSLQDALENSNHEVKGWSLALLITGLSVVVFLISIDRTVITTAIPYITAEFHSTPDIGWYGASYLLTSCAFQPVFGRVFTSFHIKWSYMLAMCMFLLGSLISGVAPNSMTLIIGRAVAGFGSAGILTGSFVIIATGVPLKSRPIYSSIVGLMFGVGATVGPLIGGVFTDLAMVFLYQPPPGAVTLIVMALVFHPAPQSHLHRPFLERLIDLDIIGNFILLSTSVMLFLALEFTTTGDSWGSAKIVGLFSGFGAGILAFATWQWWKQDGALIPPSIVMQRTVAAACLGLGYTAIQSGVGMIPYFVANALFSLFSGIFVSKVGYFTPPAILGSVIYIVGCGMFTLFHPNMSTSMWIGLQILASAGFGMSIQQGFTAVQTVLSKDDIAVGTASVVAAQSLGGAIFISVGNNVFQARLRSIIAADNLDSIDVDAVVAAGATAFRHLVPPNELTRLILDYNGALQTVFLVAVPLASLALVANCCLEWNSVKGKAPSTFEGSEKGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV93</accession>
    <name>A0ABR1VV93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein frg1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FRG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665677.1">
        <property type="nucleotide sequence ID" value="XM_066813715.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046775"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23339">
        <property type="entry name" value="beta-trefoil_FSCN_fungal_FRG1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010414">
        <property type="entry name" value="FRG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12928">
        <property type="entry name" value="FRG1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12928:SF0">
        <property type="entry name" value="FSHD REGION GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06229">
        <property type="entry name" value="FRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="Actin-crosslinking proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="268" mass="30072" checksum="7650FD0DD593C842" modified="2025-10-08" version="1">MVKPLSFKGDKKPKKRKRTEAELSNAEAGPSERAVVKTEEAAGDDDSWVSAEAVGDLVGPVMFVLPTDPPTCLACDANGTVFTDPIVNIIDENPTTSEPHDVRQVWIANKIAGTEQFRFKGRYKKYLSCDKYGILSATSEAVSPLETWNAIPTSDTPGTFQLQTLRETFITVKESTKVNAAPEVRGDATDITFDTTLRVRMQARFKPKLKATKEEKAREKISRKELEEAVGRRLEEEEVRTLKRARREGDYHEQLLMLKVKSKHDKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVI5</accession>
    <name>A0ABR1VVI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX hydrolase domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666194.1">
        <property type="nucleotide sequence ID" value="XM_066814232.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047292"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051325">
        <property type="entry name" value="Nudix_hydrolase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340:SF0">
        <property type="entry name" value="BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340">
        <property type="entry name" value="DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="175" mass="19444" checksum="91FEFA0694ED8DF4" modified="2025-10-08" version="1">MASEKNGLFFSNQFAISCGTVSVDFERSKVLLIRWQDTGEYLLPKGRKDLDESLEQTAKRETFEETGIQVELLPVGIDTMATLPSSMKVEDRPRAVTEPIAVAQRVTKGILKIIFWYVATADSTVMPTKGMQQENENFDTIWVDFDDVGSTLSFDDDQRIAQAAIDAASKRVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVI6</accession>
    <name>A0ABR1VVI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF423 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009914</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666191.1">
        <property type="nucleotide sequence ID" value="XM_066814229.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047289"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006696">
        <property type="entry name" value="DUF423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04241">
        <property type="entry name" value="DUF423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8075251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="171" mass="17742" checksum="F6B9DEB0110456DE" modified="2025-10-08" version="1">MSPSDRVHIAVDEQSSLLHQHPREGRPEDLPSSTNTITITHAAATAMSILATLAAVSGATGVALGAFGAHGLKKRISDPARLQSWGTAAQYQLIHSVAALVAANTMGQTRAGRWGAGLFLAGVSMFSGSIYLLTLDPARFGKTLGPVTPLGGLCFIAGWTVLAVGTRGRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW93</accession>
    <name>A0ABR1VW93_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666446.1">
        <property type="nucleotide sequence ID" value="XM_066814484.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047544"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02208">
        <property type="entry name" value="cupin_RmlC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="58"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="144" mass="15687" checksum="72CE1F16E404E817" modified="2025-10-08" version="1">MSIFSLLPDILPMILPSAVHVTKAEDLEAQRATSSHPGMVRQGAIVGKSDKMCATDTIIYAASGTGILMTNPGSEGDLVKHELSPGDFAFVPPWTEHQEINDTDEDLVWILIRNGPEPLVFWLTDWGGDEAKKSSTEEDAEAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWY0</accession>
    <name>A0ABR1VWY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666700.1">
        <property type="nucleotide sequence ID" value="XM_066814738.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047798"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="302" mass="32803" checksum="C45FBB997596F3B0" modified="2025-10-08" version="1">MPANQPQNQTSWGTTIYTLEGSIQEFFQTFGGTAVTKSDCDAKAAALGHWSYTVVAGSPEQARIVQFRAAKSKLDMTIMDLAASVHPDLVPKCSYHGLIGDDASPLHVYVMDKREGLCAFESRDSSVEGGASVCGSAVPDGAFFAEAWKKPQQVTPAAAEKMRQDIDADLNCLAQSLPERFLATVKQVRADLTGIIDWAEADISPFGLSVWGLESILGYSRKRVWYAYDNAEQLRAEFWRVFEAEAGTAVLSDEVRHAIKVARMAGMLLAWCFEYEPGAGRGKMRGLDVGLGRADAFCTGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY79</accession>
    <name>A0ABR1VY79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U2A'/phosphoprotein 32 family A C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009803</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SDS22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666080.1">
        <property type="nucleotide sequence ID" value="XM_066814118.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047178"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050576">
        <property type="entry name" value="Cilia_flagella_integrity"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003603">
        <property type="entry name" value="U2A'_phosphoprotein32A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973:SF23">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00446">
        <property type="entry name" value="LRRcap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="U2A'/phosphoprotein 32 family A C-terminal" evidence="7">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="385" mass="42938" checksum="B203AC537623F2DA" modified="2025-10-08" version="1">MSGQTNEDAAAAAAAAAAGRESPARHIELVEDDAHHGNGAPSPALTDSKGWDGKLRVDRTAQLQNPEAISDPEYSDDENVLPGESISADEDILDDEDPETEDIALIQARIADIPALRLERFKKVARLCLRQNLIQHIGGLSSMGPTLEELDLYDNLISHVRGLDDLTQLTTLDLSFNKIKHIKHIAHLTKLTDLFFVSNKISTIENLETLVNLRQLELGSNRIREIQNLDSLKNLEELWLAKNKIAEIKGLDGLPKLRLLSIQSNRIKDLTPLRQAPQLEELYISHNALETLEGLDGNPNLRVIDISNNMVKSLKGLEGLTHLEEFWASYNQVGDFADVERVLADKKELTTVYFEGNPLQLRQPALYRNKVRLALPQLQQIDASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYJ1</accession>
    <name>A0ABR1VYJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009908</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666185.1">
        <property type="nucleotide sequence ID" value="XM_066814223.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047283"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="32993" checksum="E2C4A6AD04CEF856" modified="2025-10-08" version="1">MSSSTPQTPNVWFIAGASSGFGKHLALEALSRGDSVIAASRHTSGPALSDLSDRGAILLDLDVTASDETIRAAFARGESALLGSASKVHHITHFVNAAGYILEGPIEAASQQEIFDSFNVNVLGIMNMTKNEIGWLRKRGQTRRGQAGRSVIANFGSLGSWRGGPAFAYYAAAKWAVSGFTESLAAEVKELGIDACVIEPGYFRTGFLNPGGGHRITMRDPLDAEYTGTQVEHLRGLLEQVKDQQPGDVVKGCKVIVDALTRSGSAQGKEVPVRLPLGQDCVDVIEGKMAETQALIDDWRAVITKTDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7H5</accession>
    <name>A0ABR1W7H5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007253</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666910.1">
        <property type="nucleotide sequence ID" value="XM_066811568.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044628"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047521905" evidence="3">
        <location>
            <begin position="21"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="328" mass="34742" checksum="FC99E2B5ED91E812" modified="2025-10-08" version="1">MRFSLLGQYLAVGLVSCVAAQEVECWAPDGKTRADNETYVPCNKLGIQQDGIFSSCCALDGNPDKRDTCTSLGLCNGADRRLRRGFCTDKSWKSKACVNVCITTEDGGDPSNSSVITGCNDGSGKYCCGDTTSCCGTSRAVTIPTQESVCTAHTLNSDDGSGDAATFKNATIGLAVVAGVTLLAAVASTLWFLRQNKSLKKQLADEKLAAGHQQASMMHNNRGSMVPTMTDSNHPGGSVYGGSTTHHPSPMPDHSHPYHKAPGSSPPPHPPLSPHSDGHHGNMQRYSELDAGTNRIEMASPDPYAQQNRNSTQPSYSSPMHSPGLPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8S5</accession>
    <name>A0ABR1W8S5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine-S-conjugate beta-lyase</fullName>
            <ecNumber evidence="3">4.4.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cysteine-S-conjugate beta-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_007707</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.13" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667364.1">
        <property type="nucleotide sequence ID" value="XM_066812022.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045082"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006238">
        <property type="entry name" value="Cys_b_lyase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01329">
        <property type="entry name" value="cysta_beta_ly_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF50">
        <property type="entry name" value="CYSTATHIONINE BETA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8079889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="439" mass="47320" checksum="AD08CEA0BDA4D107" modified="2025-10-08" version="1">MASPPDNSTSSAPVNKALDLDGHNLPPSPAPSSPTNGRRRYALATELVYTDSKDQYGASSIPIYQSATFKQTSASGGNEYDYTRSGNPTRTHLERHMAKIMNATRALAVGSGMGALDVITRLLRPGDEVITGDDLYGGTNRLLTYLSSNQGIVVHHVDTTEVDRVRDVVTDKTAMVLLETPTNPLIKIVDITSIARAVHEANPKALVIVDNTMLSPMLCNPLELGADVVYESGTKYLSGHHDIMAGIIACNDSALGDKMYFTINSTGCGLSPNDSFLLMRGVKTLAIRMEKQQANAQAIAEFLESHGFKVRYPGLKSHPQYDLHWSLARGAGAVLSFETGDVTLSERIVEAAKLYGISVSFGCVNSLISMPCRMSHASIDAKTRQERQMPEDIIRLCVGIEDVHDLIDDLSRSLVQAGAVNITLDGFHANTGASTDQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8V0</accession>
    <name>A0ABR1W8V0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Orotate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_007737</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667394.1">
        <property type="nucleotide sequence ID" value="XM_066812052.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045112"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683:SF1">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="61"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8079919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="228" mass="24738" checksum="AC771611C988A4D1" modified="2025-10-08" version="1">MSLESYKETFLQAALRGSCLRLGTFELKSKRISPYFFNAGDFYRADLLSALATAYAHTIHANFSSGSDLQFDVIFGPAYKGIPLATAATLALAQLDQARYGSVEYSFDRKEAKDHGEGGSIVGAPLKERRVLIIDDVVSAGTAKRQAINKIRAEGGIVAGIVVALDRQETLPDSQGSAIGELRREYDIPIVAILNLEDIIHGLKSGAFATEDQLKAIEEYRSKYGASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W948</accession>
    <name>A0ABR1W948_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NUC153 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007824</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667481.1">
        <property type="nucleotide sequence ID" value="XM_066812139.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045199"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039754">
        <property type="entry name" value="Esf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012580">
        <property type="entry name" value="NUC153"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056750">
        <property type="entry name" value="RRM_ESF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202:SF0">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08159">
        <property type="entry name" value="NUC153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25121">
        <property type="entry name" value="RRM_ESF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ESF1 RRM" evidence="7">
        <location>
            <begin position="237"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="NUC153" evidence="6">
        <location>
            <begin position="695"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="150"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="283"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="463"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="706"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="487"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="535"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="607"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="646"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="663"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="725"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="750" mass="84147" checksum="58EB8B4D65A269FB" modified="2025-10-08" version="1">MVVIPSPIFCFWHWEGNRSAAGIGGGAVARSWINGHGGVTKSSALTALAEMCRLHWAASLQGELSKMVKKTQKAGSGSGKGSAITDSRFANFQTDERFRLPSRKLGKTKVDSRFSKVLKDDEFTAAATVDRYGRKLKADSKKEALKKLYEASDDEDDEDDIKDVEVEDDEVVEKELKKASKNYDPARGGGFSSSESESDSESDEEEEETAAEASTKASSSMQRLRDEEADVETGEVTSRLAVVNMDWDHVKSQDLMALFSSFVPKGGKIERISIYPSEFGKGRIEREELEGPPKEIFKKKADSEDEESEDEPEDSDEDEDEKIKQDLLQEEDADDFNSDALRKYQLDRLRYYYAVVDCNNEACAESIYQATDGTEYQTTSNFLDLRFIPDGVTFDDEPRDSCTEVPASYRPTEYVTDALQHSKVKLTWDMHPEEASRKEDIKRAFTGSRSDIQENDLRAYLASDSEDSDAGADGFEADDGTPADAPKLSKKELARQRMREALGLGAETSAKSSKKEPTGEMEMTFTTGDFGGGETKTDAPEDETTVERYMRKERERKAAKKDKSLSKRDGAKPTEAPKENTEQDGDLGFDDPFFTTEGPVKVSKTSQKKEERLKKRAQKEAEATEDAAEKARLQKLMTDDATGAAEHLDHFDMNEIARAEKQKNKKNKKKHKSKKKDGAEDRGGLQQDFEMDVADERFKKVFESHEFAIDPSDPKFQATPGMKKLLQERRKRTTGEEEKSDRSNKKARRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W966</accession>
    <name>A0ABR1W966_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007829</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667486.1">
        <property type="nucleotide sequence ID" value="XM_066812144.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045204"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="4"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="363" mass="39035" checksum="05838A57963A9236" modified="2025-10-08" version="1">MAPTIVVLGGSFAGLQVAHRLLKHTRNTHKDIKVILVSKDSHFFWNLASVRAVVPGVLKEEQYNLPIEPGFSKYPAENFEFIEGSAEAADLDAKTVRVVTATGERSLSYDHLVLGTGSRYMDANSPWKANGSNEEVMASVRATQEKIRAAQHIVIAGAGATGVETAGEIRYEFKDKTVVLLSGNDQILGGDAIAGNAESELLKLGVQVRLNARVKGSQELPDEGAEILTDLYLPTMGVLPNTDYLPAKVLRDDKYVLADEFGRAQNAENVWAAGDILSQPKAGFMIADKQAAGVAKNIDLVLNGKKTTPVKLIPVDVFVCAVGRGRGAGRMGGIKVFSFMVYMIKVKTLGMQMMPGIVDGSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9Y1</accession>
    <name>A0ABR1W9Y1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667748.1">
        <property type="nucleotide sequence ID" value="XM_066812406.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045466"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="200" mass="22226" checksum="9A123953C163ED36" modified="2025-10-08" version="1">MAHRTLPPLRPTNQKQSKRNGSSSSSSFSSSSSSSSTSRSRAPSPHPLSRAHRKQILQQLESSRTGHWNGLRQPQTSNDNEDIASSPVSSKTNVYLDDFHQAATTDRAVLPFMNPQPNSSLSSGAQDAKTSTEEDAQAQEPAQQQQEQEQSFQEYWDKFEDFNVAQIPQGYYDADEAESTESRRAGGGWPSSWFGRGHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAF2</accession>
    <name>A0ABR1WAF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aurofusarin cluster transcription factor aurR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007835</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667492.1">
        <property type="nucleotide sequence ID" value="XM_066812150.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045210"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF57">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="171"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="536"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="599" mass="68528" checksum="0104B8E3CB8A4158" modified="2025-10-08" version="1">MQDRLERLERLVQGMNFVGGPSTGRESRLSSTEAVIQGWSPESSSTVESEDQGVQLSEPNICYYMHPNYWLNLEEFVDEPRDLLRWPYDDKMNSSWPFSAQSIPPILTEGLAPLHLPVEQQDLLHDWFYKAVDPWIRATHYRAYMNEVSNVRIGKSIMPREIEAVIFSVQAVTVAAMPGDQVQQQFGRPREHLLSHFQSATELALNRANLLRSRNMWLFMALLHYITFLFHTGQAEKATSFLGTATRIGMRLGLHKDPSAHLFTPWVAEMRRRLWTYFLIMDQPIYNSEGAESLFDTLPWIPRPVNANDNQWPPHRFMKPEQVPADADGFTDMAFANIRRELYYMGREVGRLSRMTEPERLVAIITDCDNAIRRKYIDHMNVQRPIQAVIIGYYSFYHRCLRINVEVTAVKSRAQSELPEDIHTRILTTQLDLFEDLERTEAIAKQHNWHWIFRWPPPFHGIARLLHSLAEVPKTAEAERAWKQVDLIFRRHLGDDMAMHDVPSWRLIERLCDIAMFAHSSRAHQGAAYTLRGQPRQGNTDGETTTSTGLSLVNQSAYPGFGTASYNGSASVGSAAHAATSSSGSMMQYTSAEGNAFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAL8</accession>
    <name>A0ABR1WAL8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Purine-cytosine permease fcy22 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008363</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668020.1">
        <property type="nucleotide sequence ID" value="XM_066812678.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045738"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF5">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="518" mass="55846" checksum="857191FA48F3901B" modified="2025-10-08" version="1">MASEIPPGNDARLHDDVEAGAGTRKHGGLASYLTVEDGVVYKPGLESNPRWYQRLLDAGVEDNGVKPVPVESRTDTRYHNLFTVFSTALLCVLPCLSSIPTGMLGTTAFGMSLRDASLTILFFSLLCSVPPAYMGCGGYKTGMRQLVQARYSWGLYIVTLPLLLNAATVTGFTLISAIVGGQTIAAINPGHVSVDVGIIITILIGFGVSFLGFRALHAWERWSWIPNLIALVITVGCGGKFLVNQAETEPVTAPQIVSYAGLIAGYFITFGGTASDYSVYYNPKASKVKIFTYIYLGLLTPSVPLLILGAAMGGAVPVVEGWTEAYNSYGAGGVLAAMLEPAHGFGKFVLVLLALSVLGQLAISMYSIALNLQMLVPIFTKVPRYAFIVVVSVVMIPIGIKVAEQWETSLENFLALIGYWAGCFDAVLLEEFLVFRRRDYAAYDHAIWNVGGKLPSGLAALAASLLSMGLVIPGMAEAWYTGPIAEKTGDIGFEMAFFVTGIFYLPFRWLEIKWRGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB19</accession>
    <name>A0ABR1WB19_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668082.1">
        <property type="nucleotide sequence ID" value="XM_066812740.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045800"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="320" mass="33752" checksum="789A397D7CA839A9" modified="2025-10-08" version="1">MADFAWPQLDASPASTPKSSSSAPLRDDPQCPPPLTLFQEAQVVIPGNGGGACNLPSAPQTCGVFEENLEEGQNGDVGTNTEDAAAVSSSTHSFLESPGGWPLALEEASGAVTGHHCQCLQGLTSSLSMLRCSLARYQGGLEADLGIRASDVSGGSMSSSQVRADEFLELFEKVFEKLRRAETCPLACMLSQDLAILLLLVVEQLVELLLGFATDLFIGSAASSLSSSVLGPEGDEARQQNAAAGRSGSSSWRVSVGAFEITDPTEHQLLVKQLLQNRAQGLGAFIAKLSDMMKHKGLNGLGTDLRRIREGLCNTLQNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBB5</accession>
    <name>A0ABR1WBB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668264.1">
        <property type="nucleotide sequence ID" value="XM_066812922.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045982"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="16"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="230" mass="26366" checksum="C335B3B4F8DC1178" modified="2025-10-08" version="1">MGSKQMVGYLQKCYRSRELGSEINALKRQLKRVIDETAVFDETIEVNAEKDNVSQACETAERQEQQRLKRAGHQIKTRLEEMCDILDEKIDSCNVTIDNMSLTMQTLWNHFAQEDNKLNTKFNRVNTHLSTTNKEISQSMQDDSSQMKFIALLTMVFLPISTMASIFSTELFSWDAGPGEAVISKYLWVFIVISLALTTVVVGAWGIATRYAFLRRKKLDDENKDYEKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBF4</accession>
    <name>A0ABR1WBF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668297.1">
        <property type="nucleotide sequence ID" value="XM_066812955.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046015"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20273">
        <property type="entry name" value="Complex1_LYR_unchar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046896">
        <property type="entry name" value="Cup1-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="2">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="310" mass="35269" checksum="A199F8F211EB31CB" modified="2025-10-08" version="1">MPPQLPHPDTTIHLYRHLLREATYVPPYCRPWVTERIRSKFRDDRRPNIHKAHQSLRYLRSANAGHVNRMLHLCFLASGRLGKRRRQLADFYLAKDPVQMRKTYDPALVLPKENVWGRPFTPKVMRRKEQKHYAKLLADLMPPVPQGEWDLLQALSLGQAETDMFNVPSRRTVATTPVASQDSATNTAQEWNWEAYVTKPVRAVERGNSRVFKSLSGACDSDPRGQGKPIGVKAFSPRRLRRSIYGRVWEASPILTKTKGKFQVTFGGARRELSPATNSDLQFFSGVDEQGASPKGPVAHKGNKRLNQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBW5</accession>
    <name>A0ABR1WBW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667430.1">
        <property type="nucleotide sequence ID" value="XM_066812088.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045148"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="400" mass="44610" checksum="32FA426E7F83A647" modified="2025-10-08" version="1">MSHGIAKSITWQLDADMFSQKGWSGYTCRHRRDNPFIPLGKLDSYAAIEAGDRACREQGLSQRHLTVLLMAEYPARLSDPRKKGLGESEEYLLTAFMASITILHECTQGSWADGGLVGNKMGRLAHAVYWRDFRSLSKDMREPYYGADLEMELGESFIAHLFGGYVPVPVKGITDRKDGLAWKQFLSWDCHRPPIAAIYTIGTAIAPRESRVTCCRISTSDEGWKWNRRSGAPFRIPQYDDYICPDLSLPIAPEYVMMEPQPRRWPQDTERLGVSSPPSTINKPRLRQDGEPTAIQAAGSSSMSSSTASRGDPVHGTTAWVDPTRSRSYPEVPRIRFSGLDKMSGCTGDLMGRKPPGGIGAITCELTVDELKKGLSHLIGVSLCELETLFDDQRNLVRQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBX6</accession>
    <name>A0ABR1WBX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PWI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007487</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667144.1">
        <property type="nucleotide sequence ID" value="XM_066811802.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044862"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12446">
        <property type="entry name" value="RRM_RBM25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052768">
        <property type="entry name" value="RBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034268">
        <property type="entry name" value="RBM25_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806">
        <property type="entry name" value="RBM25 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806:SF4">
        <property type="entry name" value="RNA-BINDING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWI" evidence="3">
        <location>
            <begin position="673"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="90"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="368"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="546"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="437"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="546"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="766" mass="85039" checksum="3E1E71EF524E8B93" modified="2025-10-08" version="1">MSYNPYGGVPGFGPPPTYNSYPGANGAPPGMPSAPGLGPPPGMSAPGTAPPGIQQPNINQANRPSGLPTSFQAPPNMPNINFNAPVIRLGTLPAKPTTPGLPSRRDSEAPMSSGGPNRPGVGMERGGLDQTRQAIRDNMQALIPPTKEELIRTMFVQGITDGVGGNDGIEQMLKLAGNLRKWDRATDAHGKDMTFGFAQFEDAESLWVASELLKEIHIPTKKQAPSGEAPTDEDDETYEKFDKSKLQFKLDENSVNYLEAYNENRGSEADAKLEAARGALKQMVRKLFYPPAKPGADADGDVAMGDASGQSGDNVEVVNIPLAQEDELADIPAEMRETVAAEIAAFRERSIKRDLERLKREEELEALERQRANGTRASRMTSPPPNNNSNSNNIPLGPRGAPSGPKSQKTDLGKDYNRSVNFVNGGVTNGGLHLNRDDDETDASDDELEKRRVAKQNAETEKLYLDAERRWLNRERSRAAALEREKDRDDSDEANIARKREELLDRFKHFDDDAEATRKKEYFADRSAWIRNRTAFRAREIAADDADRAAEEREHAKEAAEQEQARGMADSFLERQAQEMQQREDSRAAMPAPQPFKLSLGAAAQRAQAQRAAPQRKTIAEVEGLLEDEEEDSSTRRQLVPIKFEPMAAAGMSDEEREQAVRSLAQEIPSEKEGLWEWDVKWDFLDETVIRDKLRPFVEKKLVEYLGVQEELLIEVVEEHLRKHSKPAEVVEELAEALDDEAEALVKKLWRMVIFFTESEKRGLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCG7</accession>
    <name>A0ABR1WCG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668592.1">
        <property type="nucleotide sequence ID" value="XM_066813250.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046310"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045162167" evidence="2">
        <location>
            <begin position="19"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8081117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="267" mass="28122" checksum="A07B180DC2D6A4BD" modified="2025-10-08" version="1">MFFSHILGSLTLAAVAVAAPTPEHPPLSDRQAGTPYTGILTPAQCEVLVPRKTAGDADQGGLGLALENADKQPRSYFVYSNGCDTMPYIEVAGVPAGKTVFVSLPARFQGRVQRGTHEVHVARTKGDDTSLGTWLELGYDADGKSYGDVSLIRGCDGAVSLRTTDGTGVATGFSAPCMQGAPAGAIGTKPSGGKSVKATERSKTQSDADPNDGRPVVLPVPRDWLLKKLSDDKGKAETKAYIDDFHGNPVICDTKGRWHATFHQGNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE86</accession>
    <name>A0ABR1WE86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668286.1">
        <property type="nucleotide sequence ID" value="XM_066812944.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046004"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="149" mass="15495" checksum="1B26BF919EEFFE81" modified="2025-10-08" version="1">MKYCCGGDHNSCCNDLNLLQSIPIATAIFHSPQPAAAASASSTQPVQSSCNSNNSNPHGLAFGLGVGLPLGLALLGGIAFLGLQLWKWSAAAHQLTTERERGDGSVGGDERQGQQQQQQSADCRRGVTSSFTADPPSRLELGGGRAEMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLJ9</accession>
    <name>A0ABR1WLJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668899.1">
        <property type="nucleotide sequence ID" value="XM_066809976.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043036"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="224" mass="25328" checksum="D717D146AE4C62AF" modified="2025-10-08" version="1">MPKGRKPLSPRSLSLESPSPESPSPERRNSQTASQTVPPPERDVCRVCKIGRHSPLRCMLTDGETGMTKVCPIHPNQADHGLDDCYELLVYLTSRDLRETLFHRMGPDRRGMPPIYTKLIDVNELAHYHAANFDLVPWSVDHSVAQWRDKGQMLIEHLQYSYRPDLPRDCAENDRQKISSFQTVDGQHPTHGDLDSLVAHLKTQGSLLGSVEAFVKAQKNLLRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMG5</accession>
    <name>A0ABR1WMG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005894</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the complex I 30 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669132.1">
        <property type="nucleotide sequence ID" value="XM_066810209.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043269"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="entry name" value="NADH:ubiquinone oxidoreductase, 30kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01357">
        <property type="entry name" value="NDH1_NuoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020396">
        <property type="entry name" value="NADH_UbQ_OxRdtase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="Nqo5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00542">
        <property type="entry name" value="COMPLEX1_30K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase 30kDa subunit" evidence="5">
        <location>
            <begin position="108"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="247"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="272"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="282" mass="32080" checksum="87A52325612900E1" modified="2025-10-08" version="1">MATKLSRSRALASALRPTKPSISARSTEQFARCISATARNNVVAMPSDAKDPRKAPRDHAKELKAPIVNPADKYQTKADDMHRYGSWLMGCMPKYIQQFSVWKDELVIYISPSGVIPVFSFLKYNTAAEFTQVSTITACDFPTRDQRFEIVYNLLSTYADEASPVPSVTPLFDGANWYEREVYDLFGVFFVGHPDLRRIMTDYGFEGHPLRKDFPLTGYTEIRYDEEKKRIVTEPLELTQAFRNFEGGSASWEPVGSGIDRKPDTFKLPTPKPEEKQEEPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPG9</accession>
    <name>A0ABR1WPG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL40</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005622</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668860.1">
        <property type="nucleotide sequence ID" value="XM_066809937.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042997"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019192">
        <property type="entry name" value="Ribosomal_mL40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042831">
        <property type="entry name" value="Ribosomal_mL40_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39150">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39150:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09812">
        <property type="entry name" value="MRP-L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="22412" checksum="8EFF44E93D07264E" modified="2025-10-08" version="1">MSTSSLRSLFSGLSLSTTTPLSSTACQRISSTLVRSPTAAAIALTPLQRRSFSFTSPAPAKADKSSKKKRKKGKGDEPDPRIQNLKVSNPRKVPAPLRFARNRALRHWTIHRAWLLFQRKEREREEKELARLYQSMHSACEELRQTSGPGTQDEGYLYRVAMEKKGVFKHHNFPIEYARPQVETPAREPWNHGWTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ36</accession>
    <name>A0ABR1WQ36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CND01770-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670158.1">
        <property type="nucleotide sequence ID" value="XM_066811235.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044295"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="13986" checksum="B5F8CDB743BF3022" modified="2025-10-08" version="1">MYIPNAQSVLTAGLAMTGLLTEPSRVAKGEVMDYAVEKCIDKDGNIRCSKPFTVAKSTCYKIEWSTEGTLTHTTAEVRDAGSGELVYYRDTDGDWTPEKGELVYLDFKPKVVATGNQTVSYEVKTCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ60</accession>
    <name>A0ABR1WQ60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cutinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006953</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670191.1">
        <property type="nucleotide sequence ID" value="XM_066811268.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044328"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF13">
        <property type="entry name" value="ACETYLXYLAN ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046223520" description="Cutinase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="24745" checksum="7DA7F7585BF22536" modified="2025-10-08" version="1">MHTPSILVSALALAQAAAAAPSAMPRQAPANCTNVQVFVARGSLEEIPGRQGKLVDAVCKDMPAGMTCGSTDIQYPATFDAYCKSVGSGVAFALKAVEDYAKACPDSKMVLTGYSQGAHLMGDVLSGAGGLIPNQNCTQAKTAPLAADAVKKVAAVTLFGDVRHTGNQTYNLAEGAGKSGILPRVGAQLKDLNVHSNKIHSWCNGQDPVCSSGNDMDQHLTYFDQFTPDAAAFIKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWV8</accession>
    <name>A0ABR1WWV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Regulator of nonsense transcripts 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002588</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670521.1">
        <property type="nucleotide sequence ID" value="XM_066806903.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039963"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="8">
        <location>
            <begin position="300"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="9">
        <location>
            <begin position="588"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="159"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="857"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8087627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="919" mass="104109" checksum="401E609308125F2F" modified="2025-10-08" version="1">MSLLYEVFKRQDYRTMIEYIQSDTPVAQNFKWKQVQEIKEFLKAKDSFSSVEEYVATIMMGAKIIQVITEYEQGFVFDNSTIRILKQKDHGLIAVVELPKFHREAIKDRDALSISPGDRGFLRLEYRTKGEETGSVPTKVVVRLHMEFIEPLPSSPPGVLAAKLKPRQKRPKKSDSDHSLGKDEDMPDLYTTPNIGDLHNSLTNKKTMAFVLKTLPQIRVPGSVIGPDSIMRYILNQPGLKGEVNTVVRHTEFVYVYQAVSGIPTFLRSYLAFGPRLQTPRFDIYSPLEDKSLVDSDCMQLNQSQRAALELGRSAPARFVIAHGGPGTGKTHFTVQLVKPFFLDKKSHQILITSAGNRGADSIALELNNWLQSLDSSIRGDSYIVRLHSVKTETSIFLKDAEEAKREALRDMAKQPADASQQSGETKGTRDAIYDHYRTFACGRFKGVDDERVQHISLSVGAIMKQRLSTKPELERLYNMYGSGEIYRDEDVEHFIRSVHIFMHQIIHGSTAVCATVSGVADALVRKAYENCELIIVDEAARVAEYQWWPLLGFYRKAVGKVMVGDPFQMEPAGGRSEERSPLRKQMAYSLQARLQKLGFKSGFFDTQYRAVPEIAAIYNQTRYQGRLKSGDETLVERRPLAQAIIQHNKEKYGVAHSVVFLDVQGAVEKKDKRGMPKFCNQYIVAVTSILENLINAGFGNGAHPATIAVLTPYRLEYKRLRYARTKMSDDYLEAEDIVIETVDKIQGMEYDIVIIDPVVTSNVGFLNHRRLNVLFSRARSGLYVVGCAARLGSLSGWHENKDDFRAFAKQLGPYTKCFPDPNDLDSNRKACPKSNKYYDPGEFEQVPEKSKTSEDIRKALLRMKEVANKKEEMEKEEALKKEEALKKNEAIKKLSASERFAMAEVFDYFQDALRHGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXB6</accession>
    <name>A0ABR1WXB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002761</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670694.1">
        <property type="nucleotide sequence ID" value="XM_066807076.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040136"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF80">
        <property type="entry name" value="GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="3">
        <location>
            <begin position="527"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="341"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="352"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="689" mass="73204" checksum="D7A4CA71111A5D29" modified="2025-10-08" version="1">MHDGRSADGECPLQDELISAAMPRPWTGPSEGACSSSSRKRNVGSSSSSKPPGPRGPAPAETCRPETAEYDYIVVGSGPGGGPWLPTWPAPATRPSWSRLVTMKAPTPTPTWPRSSRAPASRRACTGQSFYVKHYDDMERTLKNDHLVWKKPNGDLFVGPGGTEPAGSEVLGVQYPRGATLGGSSIINAGAVHLPSDSDWDLIKDLTGDDSWSAAHMRSLFAKLERNTYLPAGTPGHGKDGYLEVTIGDGNQYLASTQARDILAGMVQEIGQDPAKLPELLTADVNVLDPQRDTTTGAFALPFHVNATWGRYSARNRILDTMREGHPLSLKLNALASRVLFQPGPPGPGQVPAPSGSSTSTARARTKATCATTPARSPPPPNRSAPRRSGIGAASDLAKLDIPVVADLPGVGTNMQDNEEIGIFGLAKENFTFATPAGQTPDPVCTFQGDAADPCYALFLQGKGPYTRAGPNSNAFMLKTAHSPDGERDALTFAGPFTFRGFWPKTPGQDFTEPPNTWGMHAVKIHPQNRAGTVKLRSADPTDMPEINFNYFTDGAATDLGALQDVVAWGRRAFLNVPANSTGGAGPVNITGPPCKDINKTDGRCNDAAGKADEEFIRNQMFGHHVTSTCAIGADDDERAVLDSKFRVRGVEGLRVVDASVFPRIPGAFPVVSVYMVSEKASEDILGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXK1</accession>
    <name>A0ABR1WXK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670762.1">
        <property type="nucleotide sequence ID" value="XM_066807144.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040204"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047525073" evidence="1">
        <location>
            <begin position="18"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="139" mass="13954" checksum="8A52D8507E09A5C0" modified="2025-10-08" version="1">MYTLLTLMGLLPLSTIAMPVGEAFCKANVVVIKALLADVGGINYCSEVLNLAATTLTTTVYVTPSAVSTGLVSTITGPTVSVDLSTLTSATNTPSLATSSSAIAPVTSSAPVSFVTSTATKVETISVDVTVTNPVVQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY88</accession>
    <name>A0ABR1WY88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Emp24/gp25L/p24 family/GOLD-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003057</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670990.1">
        <property type="nucleotide sequence ID" value="XM_066807372.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040432"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046581090" evidence="9">
        <location>
            <begin position="24"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="10">
        <location>
            <begin position="38"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="24933" checksum="F67217B45A91C362" modified="2025-10-08" version="1">MAFSRSLLHYLCSIVLFITSIQALKFDMQASHQHDRKERCIRNFVAKDTLVVVTAIVGGYKNDGMQVNMKVRDALGNDYGRAKDIAGEQRQVFTSHADAAFDVCFENILTGSRTPGDPNRHIELDIDIGADAKDWSAIQATEKLKPVETELRRIEEMIGEIVGEMDYLRSREQKLRDTNESTNTRVKWFGVGTTMLLIGLWGWQIMYLRAYFRSKHLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ67</accession>
    <name>A0ABR1WZ67_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Allantoate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003386</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671319.1">
        <property type="nucleotide sequence ID" value="XM_066807701.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040761"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="26"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="470"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="488"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="500" mass="56062" checksum="F4C1A59826B19608" modified="2025-10-08" version="1">MAFGSLAFFQRHERTPEERSLVRRLDIFLMTFGCVSQNLDQQNFRNAYVSGMKEDLGLYGNELNYFEMLFNVGYAIMLIPSQVILTYVRPSYWLSGLEIVWGVITGLIAVCHKPQQIYALRFLLGLCESSAWPGMMTLLMHWYTPSELAKRMGFYHSCQAAGSLMSGALQVAITNTLHGASGLPGWRWLFIINAIMTVVAGGLGLFMLPDLPNNPNPRAFWFTKRDARLAMERLERHGRAEPKKMTWASAKRTFSSWTVYFVSVLYIATVLASWGYAYFNLFLKSLTNPDGSPVWSVTQINAIPMGGSAINIVFVWIWAILSDLLRTRWALIVAQSVIGLIPCIVMSVWTSHPDSTPVAAAYASYFISFLCLGTAPLIFAWLSDLLPQDPESRTLIVGVAIAVYYAISAWSQVLVWPAVQAPYYKYGWQSSIALWILVIIMTCILRYIDVKYLRPKREAFHATLIESAKTDDLEPSGAEGSQVAAKSSDTKAGHTDVTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZJ5</accession>
    <name>A0ABR1WZJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671438.1">
        <property type="nucleotide sequence ID" value="XM_066807820.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040880"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07379">
        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF28">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="58"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="339" mass="38012" checksum="58ED1B95CEF095FE" modified="2025-10-08" version="1">MTTSLGATSMPTPAPHTNVRIRGQRKRLVAQALLKYHQKRLRPPGKTGLSSAPVRVVCISDTHNKQPSLPPGDILIHAGDLTESGSFDEMQAGLWWLNSQPYKYKIYVAGNHDVLLDEDFLSKYPERRYGQTKTKADLDWGDIIYLQDSSVTLSVATKEAGDQGIAPSSGNKERKLTVFGSPWTPQHGISAFQYRLDAVDHWEERMALMEQPPDILVTHAPPRNYLDQRDFHLAGCPYLAETVHRLRPRLMVFGHIHVAYGREDIILDGVQRAYGKVMTGWAGWGMLAWMAISVACCRIASYLSKFLPRREQKITTFVNAAVVAGQQNELRNPPIVVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1A7</accession>
    <name>A0ABR1X1A7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004139</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-1 OGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672072.1">
        <property type="nucleotide sequence ID" value="XM_066808454.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041514"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052054">
        <property type="entry name" value="Oxidative_DNA_repair_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242">
        <property type="entry name" value="8-OXOGUANINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242:SF2">
        <property type="entry name" value="N-GLYCOSYLASE_DNA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="10">
        <location>
            <begin position="155"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="418" mass="47399" checksum="02403FDA49EC5E30" modified="2025-10-08" version="1">MTVSYSNQPKSIDHMRGRMAIGRVSEWRKLPLSLTELCIDTTLRCGQSFRWRKIEDEWHLAIHGRILSLKQDPEFLHYRSTWPAEVKGNKLTEPHSPHDDTEQLLQHYFSLKHNAAELYELWSLNDLNFRKKAPKFTGIRIMSQDAWETLIGFICSSNNNISRISQMVHKLCKYYGPLIGHVGEEPFHDFPGPQALMGKGVESHLRELGFGYRAKYIAETARLVSEEKPRGWLESLTNPENPGFGADEYPALGRATYKEAHEQLLTLSGVGPKVADCVCLMGLGWGEAVPVDTHVWQIAQRDYKFGKVKTKTFSKAMYDSVGDHFRKIWGDQAGWAQSVLFTANLKSFSDRSVVKAEVEDVKVKIEDAVSDTPDVLAAPKPRPSRKRQVAAVETVKVEEADTTSGTITRSKRRRLQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1Y7</accession>
    <name>A0ABR1X1Y7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative 5'-nucleotidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672295.1">
        <property type="nucleotide sequence ID" value="XM_066808677.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041737"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053828">
        <property type="entry name" value="Nucleosidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014485">
        <property type="entry name" value="Pesterase_C1039"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF22">
        <property type="entry name" value="ADL392WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21953">
        <property type="entry name" value="NadN_nucleosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017316">
        <property type="entry name" value="Pesterase_C1039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046067389" description="Putative 5'-nucleotidase C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="Putative 5'-nucleotidase C-terminal" evidence="2">
        <location>
            <begin position="416"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="660" mass="72820" checksum="03D00319B968A053" modified="2025-10-08" version="1">MRHFGSLLLGLAVGAPSCLACGGCYGPTSHVEHVRHVKRIQPGAPNATYGPTRALEWGQVNFLHTVWSAPKVLERGRTREGYADEWGNYGADWGDVVSFTNHLKHQAGNMGVDLLLVDTGDLHDGNGLSDATTPDAEISMKIFERLTYDLLTIGNHELYLAEVAYQTFDGIAKLWGDKYLTSNVQILNPSTNKFEYIGKQYKYFTTQHGLRIMAFGILFDFTGNTNVTMVTKAKEMVTQGWFKQALNSTEPVDMFLLLGHNAVRSSMGGTFGIIHDAIRQAHPRTPIQVFGGHTHIRDFAVLDESSTALESGRYCETLGWVSMSGFSKSNSAWAGISPNPRGVPNPTRKATANSTSPFVYSRRYLDWNRGTFEFHAVGKQDDKEFDYNSGLTTTAEITKYRSQLNLAEVYGCTPKDYCMTCAPFDSPDSIFPLLSQALAEVVINETRKDIPRYLISNTGGIRFDMHKGPFTYDDFFIVSPFRDALLYIPEVPCSKAAALLDKLNKAGASQKRNVGSMRVERDICVDPIVAPIMARDEPGHDHAFGAVTRRQVADLVPGYTTSDDFGTDGDDTTHSRIPSYSIPDYFQGAAGFGAEGCTGTADVVFVDFIEKDVLAILGSDYSSSDVTYYISSNYTTQDYLPQFVKQSDMFQAGLPNCTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X278</accession>
    <name>A0ABR1X278_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004488</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672421.1">
        <property type="nucleotide sequence ID" value="XM_066808803.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041863"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF1">
        <property type="entry name" value="GENERAL AMINO-ACID PERMEASE GAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="43"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="397" mass="43658" checksum="F0CE58A7D567C2CD" modified="2025-10-08" version="1">MLYFTVQALGELAVAFPVAGSFSAYSTRFIDPSWGFAMGWKLLGIVLNIGGTPNGGYIGVLYWHSPGAFHNGFKGLCTVFVQAAFAFAGTELVGLAAAETMNPRKSLPTAIKQVFWRISLFYIVALTLVGLLVPYTDHRLLQGESNDKMTAAASPFVIAIENAGIEVLPSVMNVVILIAVLSVGNSSVFGSSRTLAALADQKQAPRVLAYVDRQGRPLVAIIVASSMGLLAFLADLGAQSTVLDWLLAISGLSSLFTWASICLAHIRFRRAWAGQGHSLSELAFRSQCGVWGSWLGFGFNLLVLVTQFWVGAWPVGWREKSPRQLAENFFLQYMAVPIVMVFYGIHRLYFRTSGIVRTSQIDIDTGRRDFNLPILVAQEAEERRGWPKWKKLYKFLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2N2</accession>
    <name>A0ABR1X2N2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672570.1">
        <property type="nucleotide sequence ID" value="XM_066808952.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042012"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="77"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="363" mass="41109" checksum="A8B9B0EF8B4B9C58" modified="2025-10-08" version="1">MSSNVLSLLGWTFLPNLVTGWVQSIYYGVTIRAGSPRPQPGSPKYAEHRRRIHILVVSAYLLYTLYEADWELRGASTFYQDLGVPLRATEREVKSRFRRLAALHHPDKIGNNGIGDNGENNVGDYFIHLKTAADTLTDPAKRFAYERFGPDVVSWKNCATVRDYVSRGAQQLVPHYGVAAVVMYVLGLFGYLEWGRYWRWLTLVVLAVFEVYAVTRPRFPWLVGSVVNPLLVRFTTHPPYLPFQVISLARKCSITLYIAFSQLGPLLRPQQQGVATTAEKQLKQNLDRLEQTARAMDADAGRLLELEMTPFAGDPETITNMRTKLKEWLVQNTIRSDPMVRDALGRSLQKRRVDAPAGARGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3A3</accession>
    <name>A0ABR1X3A3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672795.1">
        <property type="nucleotide sequence ID" value="XM_066809177.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042237"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF49">
        <property type="entry name" value="LYSINE BIOSYNTHESIS REGULATORY PROTEIN LYS14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="506" mass="56713" checksum="57A755E7AC0FCBE8" modified="2025-10-08" version="1">MASGRRAQGCWTCKLEGDREGMPGLWHTACMARPARWPSSRQPHAGPCLAPLPANSEHYGKQFLNLTYADLSRPSHGCAGESLAVVVQEPPTPRLKRFVPFVPNMHERDTHLMRYFGYPDEQRLSAMISTIDINNGFRVELLPMALGNSSEAAHGLHNAMLALAALRKRPLSPRSGVSLSLNRNHIDLWGTVEAYPYKIKALRSLSSSISAGSIGSTATQLATSMMLCVYSVFDETEGNWNMHLNGAKNMLNQLSITGGNQFRHCFLYTWFLYHEVLGCFSNPHLYGTHGPSSLQGGRDLGLDKTIIIGSLGCSIEVMEIISYVNGLRAADLRGDAAHYSAEEKTRKNEEWHRIEAKLATLEQTLAPDSTDKLSQSERTRILTTAELYRVAASLYLQRTTNSPQALEARSIYLTQAFQLLGNLSICTSPWPLFVIACESEADEQRIEILLNLDKMDKERHIGNYYVLREVIEVYWKQHDLQADSARQSQTKWWDIVDLNTAAPWFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3B4</accession>
    <name>A0ABR1X3B4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004869</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672802.1">
        <property type="nucleotide sequence ID" value="XM_066809184.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042244"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="87"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="300"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="582" mass="64474" checksum="24F56AA23BA8CF64" modified="2025-10-08" version="1">MQGFQKTLRQGELGASCVYLADAITGPSTTTNQAPLTALQSQALAKSEFLCAPDPLAELTAPLILSLVSADAAPGEQQLDWTDGVRAYYNCVHKWYSVVHRGLFYCRIDSLCTSADSPPVPPSCSPSGFSGGCSFTLQKGSADWSFVSTKMSRELALLILAMYLSARTCSTRAGRNRAMFDSLYRIVRRSFALGISETTTPRIEFVQIGALLALYEYGHSNSALAYRTLSETVAAARVLGIRPGCTSDRDLVNANGISDMEQEQNSAIWWSSFILDQLIHRDEASTHLPFILESPEPITLLPEPGQNSTGRLQSRPRYHSRGPSNRRLPVSTGVNVNLMESFQISAKVASLLHRALRHNYETRMRVPGTLPPVETFAPLDQEIRNMTATLLKDATDWRYALDCFAMCCSALFTLYLPFLPILEAQTAAQISNNNELRTALAALRFAAQLSSDITCKMNSEITDPEQELSCRELAVLAAPTCFLVVKVYTGLRIICPEEYQKCQDAILDKYKSLKFFRCRWGIADKLMSQLNDAYGIDWYRCPEVKPVAYQNQNMKDYNLLPPPPPHTNGITMSSEGNAMDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3D4</accession>
    <name>A0ABR1X3D4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF3824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672811.1">
        <property type="nucleotide sequence ID" value="XM_066809193.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042253"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35487">
        <property type="entry name" value="DUF3824 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35487:SF1">
        <property type="entry name" value="DUF3824 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1012"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="497"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="534"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="663"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="769"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="796"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="846"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="894"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="935"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1054" mass="121066" checksum="B466A085D00503D5" modified="2025-10-08" version="1">MSSYYERDYRYSRKDDPPSSDEEKYKSTTVRRYKVGAGGSSTSRVERVDRYDEVDDDRRSRYSVRDDFRDSRSHAGRTSGDLVEVDRRTEKTYLPERPRSAFDPPVERERRVVETRLEHDDPGHRDHDRYWERETDYIREPDRRDRDNTTIVRESRETIERDQPRNYWDRQSRMPWDDHEDVRIEKHIERRSGDHVDDMRIEKHVERDHDHDHYSHHDHPGAIERYTKETEYYTPADPPPQPIVIRQKAPEPQQIIVQEAAAPPPVIIENRRPEPEYIVLREDNRQLARREPSEEYYYRREEHDSRRREDDYAMERYDRRRRDYPSEDEDYYVKRTIIRRERSSSSDHHKKRHLAEGALAGAGLSALLSSRRDRDGDLPEHRGKKVLAGAALGALGTEVMRRARSAYEERYDDDDYDDRRHRSRSKSRSRITTGLALGAAALAVAGGLKYMQSNKIEKEEATRGRARRRYSDDEYSRSSSRVSRVSRTSRSRKRSKSSAAKAAAATGAVAGLVQHYRSKSRGKSRSKSKVRTGAEIAAASLTGAAASKLWERHKDKKESRERKVDDEYYSDRDRGYSSSRSRSRSRSHSRSRSRSKPRSFTTREGANRELGLVEYGNDPLSPPSGYESAGEVRPRRRRRHQPDSVVSDPEPTRKRSKSRLREAAAGVLGASAAAIGLKKYNDVKKEKERSRERSLERPRERSVGRSAERERYEDAAAEDAAAEEAVRRESRRRNRRSRERQRQRYEEEADAGGYYPYEYDPEAPPSPPTASGGYPHPYSGAPSPGPPGPPPGPAGFTQQPNPSQMNVNAYPPHPVYNPADYPPPPGPPPPGGSRNPYPPNAPESPRRRRSRRSRPLSRSSSVDSEPAAPPAPRSRSKSVSFIPLSPQSSQTLRKLHDSQEQRSDSDSSSDRSLTHRRGRRQDKDPSSEGNDVEVLPDRFDTSGRPLEPDDPRRWTTREGNFEYRPQDRGTQIQGAWGVGGSDAEMVNRMAESVGSLLEGKSGLLGILGNVISNLPKSGGVRGAVEDAKDESEDEPERPRRTRRRRHRGDDQYRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X423</accession>
    <name>A0ABR1X423_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005068</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HTATSF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673001.1">
        <property type="nucleotide sequence ID" value="XM_066809383.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042443"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12281">
        <property type="entry name" value="RRM1_TatSF1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034393">
        <property type="entry name" value="TatSF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034392">
        <property type="entry name" value="TatSF1-like_RRM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15608:SF0">
        <property type="entry name" value="HIV TAT-SPECIFIC FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15608">
        <property type="entry name" value="SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="105"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="278"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8090107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="375" mass="42101" checksum="A04442FC3751D8C4" modified="2025-10-08" version="1">MATEAPPSLSFPIDPQEFDSDERISFSRTDNKFIAVQDDGTEFEFDSQLKRWIPIFDEELIAQQQQAYGTNADPADDEITAQPSRKRKNGGGKSDRPPKKPRQNTAVYVTGLPLDVTIDEVHDAFSRKCGVIAEEIDSGRPRIKLYTDDSGNFKGDALVVFFKPQSVEMAIMLLDDTDFRYSASGLPSGKMRVQAADSSYKKTQQETEAERDAKAAAEEGDKVVLTKPRDRAREQDKQKIIKRTQKLDAKLADWDDDDPYGGQLETNARKERLVILRHMFTLKELEEDPAALLDIKEDIREECSRLGQVTNVVLYDLEEDGVVSVKFKTPEAAEACVEMMDGRAFDGRTVRATVASGRERYRRSGKGQDEEAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4A3</accession>
    <name>A0ABR1X4A3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sphingolipid C(9)-methyltransferase</fullName>
            <ecNumber evidence="14">2.1.1.317</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_005182</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.317" evidence="14"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673115.1">
        <property type="nucleotide sequence ID" value="XM_066809497.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042557"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052290">
        <property type="entry name" value="Sphingo_C9-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45197:SF1">
        <property type="entry name" value="SPHINGOLIPID C9-METHYLTRANSFERASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45197">
        <property type="entry name" value="SYNTHASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00039020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8090221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="513" mass="58098" checksum="02E99EA9E92D54BD" modified="2025-10-08" version="1">MASEKRQGEELEGDINFIATPPQPPPKFATGEDCGVATTKVAAIHNPPLPAEGPGNESFSNYALGALMLGVPAFIARSLGGGLKTTIFFVILLAVPLLIAYWTVSSNFSPRINDKVKLPGRPVEYYITFKKDEDRLKWKGRNKIPMKTFYEMYFDGDVDFNGDCLEAMEYRHDWCNFAFTWALFHFIFFEFAPDVLFHSRQQDEEQIRPNYDRGNDHYSFFLGPRMVYTSGIFSDLTREETLEEMQDNKMAIVCEKLALKEGETMLDIGCGWGTLARFASVNYGAHVTGVTLARNQAAWGNDGLRRAGIPESQSQLLCMDYRDIPDRKFNKISQIEMGEHVGIRRLTTFFRQCYDMLEDDGAMYVQLSGLRKAWQYEDFIWGLFLNKYIFPGADASTPLANYVGCLESAGWEIKSVDTVGVHYSGTLWRWYRNWLGNAETVNAKYGQRWYRIWELFLAWSVIASRQGSATCFQIVVVKNLNANHRINGWASQFGLSGALAAARAAGKAVFPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4C0</accession>
    <name>A0ABR1X4C0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin ligase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005217</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673150.1">
        <property type="nucleotide sequence ID" value="XM_066809532.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042592"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cullin family profile" evidence="5">
        <location>
            <begin position="486"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="514"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8090256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="870" mass="98417" checksum="8594BFA9394C9046" modified="2025-10-08" version="1">MPPPLPDHSSSSPLHGLLTNGGFGAQSSSNHNNASSSSSSGALAYKRRQSDARGSEQDAKRARQGSNPAAAAPTTATDSQRMSKLLGKRPEIVDLTKPRSAIRPQDGVRKLVIKNLRTVNRTNDLEEYYNKTWSELDAAVQAIFARQQPVQPYAKLYRGVEDICRYGESKKLYEVLREHCENYLNGTLSNSIRAGAGSSNIEALRSVHKHWVVWNLQSATIRSTFSYLDRSFLLSSKEFPQFNDLAIQLFRRMVFVNSKIGPMVLQGMCELVDLDRRGDQLFDAALLKESISMLNVLNIYGKSFEPRFLDTSESYFKEFAEERSTASLKSYIMACERLLEAEDHRCNAYNFDSTTKRQLMDKAHEILIEDYSEKLLDSGSVGKLIDENAIDSMKALYDLLRLSSIQKSLKEPWEDYIKNTGSSIVNDTSRGDEMVVRLLEFRRALDVMIRDAFNQDDDFTYGLREAFGNFINDKKILSSWKTGTSKVGEMIAKYIDMLLRGGLKTIPKSLLSDNKDRAEAERSGQASTGDEDAELDRQLDQALELFRFIEGKDVFEAFYKQDLARRLLMSRSASADAERSMLTKLKSECGSSFTHNLEQMFKDQELARDEMASYKSWLENTGRDKSSVDLTVSILSAAAWPTYPDTQLRLPDEAAKQIETFEKYYIGKHTGRRLTWKHSLAHCVVKARFNKGPKELLVSAYQAVVLELFNQIEGKPDEVLSFTQIAEATGLNEQDLKRTLQSLACGKARVLAKHPKGRDVSETDTFTVNKGFADPKYRVKINQVQLKETKEENQDTHKRVAADRQFETQAAIVRIMKSRKTMTHANLVAEVINQTKSRGAVDTTEIKKNIEKLIEKDYLEREGGSYTYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7Q9</accession>
    <name>A0ABR1X7Q9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673441.1">
        <property type="nucleotide sequence ID" value="XM_066806145.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039205"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539453" evidence="2">
        <location>
            <begin position="20"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="286" mass="31148" checksum="CAB9BFD3EC1920BC" modified="2025-10-08" version="1">MRLARSVMVIFYLIITAAALPPKNNGTTSSTRRHVHDPRHQHRLGGEPDSARSQVVGNVTGHTQIFCHNETQPPIYFTSQPDNGGPGVYILNADPVPHGAVNGTMFLFYENDHDFVPYLWTVVYPPGGAVFVTPCPTFEGRIVRGDVSNFEGRIVRGDVSNFDGRKHLLGTWAELSWSTNGTAWGDVSLLEGNDGPVLVQALDAANKYKGFSIDVLSNAPAGAWAQKLGTGSWCLDKITSEGGNSVTRAWETQFLDPNSVYLEDNINPVINSINGRFAVTFYAGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X806</accession>
    <name>A0ABR1X806_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PhoD-like phosphatase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673477.1">
        <property type="nucleotide sequence ID" value="XM_066806181.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039241"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052900">
        <property type="entry name" value="Phospholipid_Metab_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606:SF2">
        <property type="entry name" value="ALKALINE PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G03860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="1">
        <location>
            <begin position="165"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="477" mass="54879" checksum="9FD354B0A3B877E0" modified="2025-10-08" version="1">MHVRGRRNPVLIALLGWLDVTRPLLSSLTALVNVLCVLSAVDFVYRGQYFHPSHELSFSRMGYVDTTSARIVVRAPQASVVELHARPDYSEPPAEDWISVIVRDLSEETDWAGTMTLDGLLPETTYTYSTNASHSGTFKTAAEHPKKWTMIQTSCGLKYLGRYLSNHTTEFMLFLGDFIYIDLPYPLGWTREHYTDLYRQTYASPSWTPALRDLPWLHVYDDHEFVNDWSGNETGLYRDAVAPYWHYQGHANPSSPSEFGAGATYYTFARGDVAFFVLDTRRYRSPAEMTDGPGKTMLGPAQLEHLRNWLRDEPRWKVVVSSVPWTQTWVSPDQSDRWAGYLHEREMIFKWMRETDGVVLLSGDRHEHTTTLFPPPSGQEGKTLIEFSTSALNQFYEPFDRFHVPVQGGDEAVYNHWRGNSKFASISFDTTEPGRWAVQFDLIVDGEKVWDYEWVYERAALGREPEPEPASRGFWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X877</accession>
    <name>A0ABR1X877_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673550.1">
        <property type="nucleotide sequence ID" value="XM_066806254.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039314"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="315" mass="33604" checksum="A22C0D80AC577F9B" modified="2025-10-08" version="1">MGFLRSQLIETRKLPYPSASYAGQTIVITGSNTGLGKEAARHYARLGASRLILAVRNLEKGHAARKDIQTTAAKGTAIDVWELDMAKYSSVQAFAARLDAELNRVDIFHANAGVVCPKYSVTEGNETSVTINYVSTFLLAALVLPKLKATAAQFIPHMSAASTAIKNGGLGASDGAILAAVNDPHFAGGAHWKEQYPVSKLLGVFAVRSIAKERPADAYPVTVNMVSPGLCHSELSREAEGCRRWRRGGAHDGGGSRTLVDAGVQGAKSHGQYLADCRIAQPSAVVLDNPDVQDRLWVELKAKLEAIQPGVTDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X897</accession>
    <name>A0ABR1X897_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isoamyl alcohol</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002108</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673719.1">
        <property type="nucleotide sequence ID" value="XM_066806423.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039483"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054293">
        <property type="entry name" value="DUF7029"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055647">
        <property type="entry name" value="DUF7223"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22974">
        <property type="entry name" value="DUF7029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23865">
        <property type="entry name" value="DUF7223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045438142" description="Isoamyl alcohol" evidence="1">
        <location>
            <begin position="22"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7029" evidence="2">
        <location>
            <begin position="152"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7223" evidence="3">
        <location>
            <begin position="330"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="56527" checksum="B20FEA7487404A70" modified="2025-10-08" version="1">MAFKRFGAAVLFLQAALQTQATALGKVESCACDKPTVRYVVVDMPPPPANTSTHAVPVAVAAAVEPEAPVTNGAAVPDSPPSLPLAVPATPIVNATRTFTPITPPGLDCSKKENIIPSANVSLYYGAAHSDAGASTLQESSLSGGLVNLTLAMSTGAVALEYIDSVTKVDCSDDSLTVSFSDSDAYKTAFDSWSSLETLFMITNHLGNCDVEFERGFFKVDKVAAGAAANTITCSASKEQMPNIAESCEMTFSSIPTTSLTKRLTVDPSVSLAFNKQWSDVTLYEQSPYVKIAADEARLAANVTFSGTFKYSFLSWKLEAFYFDLDTALDADLQLSAYVAAGYANSFRYAPDSLAYNLVDVPGVVTLGPGVAFGIGLDLATSAGVNVTAGAGISLPDGNVHLDLKGGASAATAGWQPQYTSFARISERGEVQANVSASVTVQLALKFLGGLVDLSSGLTAEPAFNNRFVLDGAQSADTHDGLDPLSPTTAETCGNGVQLQSDFLFALSGFITKYWSSQIWNTEVPIVDKCYYFNGTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8B6</accession>
    <name>A0ABR1X8B6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002039</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673650.1">
        <property type="nucleotide sequence ID" value="XM_066806354.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039414"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF132">
        <property type="entry name" value="POLYAMINE TRANSPORTER 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="30"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="462"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="473"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8091678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="492" mass="54493" checksum="906C28BF54D33EC8" modified="2025-10-08" version="1">MIKDSLFCDRENGKKMVLPRHWPLWKKITTSMFSLFPVVTIMYTTTSLSTAVPTFPSLFATSKSLASLSFSIPFLGMTSAPLYAPYLSERFGRKPVLLVYFLLYGTVVLGLTFARTLGQLLLLRFLIGLLGGPCIVMAEGTLRQLWPPERRMTYYAVLAFVQYVGAAAGWLVGVVILQVFGLPYLSITALLYASLTLAALFFVPETSVRKILRQEVDQVDETERWWRPAVLWATTIELVRGGVLQPLLMLGRDPIVIVCSLYLALNYAVVFQFFISGPILLKDKYGFTFGQTSLAFLAMIIGALISLTVNISVDFLGAWKGPRDAFGKPRTENRLLPALMGGLMLSSALFAVGFTPNPRGNIKLVFTGIVILTWGTMDILVSLVSYVSDVYSMQHAMTALSAMAFARYFAAGIMPLFAVNLAENVPTKVLFAGYGGMTLVMLPAPFVLFYYGEKLSLNSGYSRYDPNNRENGTEGEAEEDFDDNEAFGKERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8E1</accession>
    <name>A0ABR1X8E1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673671.1">
        <property type="nucleotide sequence ID" value="XM_066806375.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039435"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF29">
        <property type="entry name" value="PUMMELIG, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047010930" evidence="2">
        <location>
            <begin position="19"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="107"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="383" mass="41271" checksum="38C96A3536B17CB8" modified="2025-10-08" version="1">MLFRSLLSLSCVALPATALLPDKSNPVTAQPNNCREISIPITLQVPRFLISTEINNDWDVAALTFNLTRRDFGQATFPLPITGTTAAPVKSTYSVGATLCGNGSTTLILTHGILESKLYWQPDFPGSERNDFVKAAVKAGYSVLSYDRIGVGSSSRVNSLTDAQFQVQVAVLGSLVSHIRTASTAPTPARKTVLIGHSYGAYLTAAAAASNQSRNAIDALILTGFAGGFSHFAPFLAGAGLRVARDQRPRRWGALDAGYLTTADRYADAYIYYHDGDYERRVAEWTHERGSEPFAVGELPSLLATNITYEDITAPVQIVQGRYDVSACGGNCDGQLGEIRGNLTGAKVVETVEDLPAGHNLNLHLIAPKAFELMFDFLRRQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9B0</accession>
    <name>A0ABR1X9B0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NADPH-dependent 1-acyldihydroxyacetone phosphate reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002412</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674023.1">
        <property type="nucleotide sequence ID" value="XM_066806727.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039787"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8092051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="33837" checksum="7F13F2FE6FDBA1C3" modified="2025-10-08" version="1">MKHLPSYTLPKTAKQCVPGDMAISKRTALITGCSDGGIGAAMAKILREKDYYIFATLRNTSKAGTLRDLSDVEIVELDVTSDASIARCAEHVKERTGGTLDILVNNAGRDFLMPLLDVNIGEAKKHFDVNFWSVLAVTQAFAPMLIAAQGVIVNHSSVVWNLAIAWGGIYSTSKAAVKQISEVLRVELQPLGVRVVTAIIGAVDTPILENSHPGPFQMPSSSYSEPVRPIIAEICQGKTRAGLTAVDEVARQLVDDILGGAQGPVWRGATSTVCRWLSSWLPDWLLDPINNGARGTKELRQYYLSNPPGMSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9C7</accession>
    <name>A0ABR1X9C7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cargo-transport ypp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002346</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in endocytosis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YPP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673957.1">
        <property type="nucleotide sequence ID" value="XM_066806661.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039721"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051722">
        <property type="entry name" value="Endocytosis_PI4K-reg_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23083:SF464">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT DOMAIN 7, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23083">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN, TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="688"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="769"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="790"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1170" mass="129248" checksum="EE4C28C0C4613C57" modified="2025-10-08" version="1">MSVSCSPCPPLLSTRQALTRRNPQNPVKGERYLALLDDARCEGRWDAVPELVRKVRKHAPSRSCLATTAETECAITKEQDKQTSRPTTALPENAAITEQLQKLQSALAGESTHLEDRFQAQVCIGWTYWALSDYSTAAAQLHEGSDQGYSQFESSETATSEWTKFWAELFLTEYCMLHAQSLEQGEKTLEDPNSLAPFRTWATYWDTSRTPTTSVTGGQGFRDAVPRRRVWYEYYGAISAILRQDLPFPTGFVDKAPDDEASAKNQLRTELKKVEAAYEALLLTETTFPRADEEREEVELFVQTVMVNWTILGGRDWDEHDLGHGGKEGLSRGVLDILYRAATKTFHSTAILRHLFTVHLAVADFDLAFKALDSYLEIVKKGKARVDKTGHPEPSLDDDATVLETLSRAITALCKYGFADEAEKARKLGEELEEMLEKLPGPLPKLDEQIPTLTEETEDSEPLHPRIPAHVNALAWQAIGLSQAQWSRKTYSAVVRAEAQEKAIRCFQKSLSPETGNPTDVRTLFALGLLLAEQRKLSAAIDFVKAALMSNKKAGDQGSPSDAYWRERSLIPLWHLLALLLSARQEYVMAARACEGAFEQFDDPTVLFGSENLDGGAYRSEHLNEVEGNAKTHGLVDDMDDIEKEGIVEIKMTQLALLELLEGPEVAVNASHELLVLYTRLFGSMQPSLPSAERRNSVSGPKSADEKVQTRRASIFSTKSRTARRASVAEGETSRPQTAGSAIAAAQPTIQVTKENGDSSDWKSSGSVRSRHRSGSTKRGNSLRKKRESTGSVQRSTSNSEPPVPKMPSVLDGDAYFTPLGETPAGERPDFFSWSSKNHISSSQSLSAGRGLQRYDSTTSAKASTVGEEAVILESLSAPNTLPAIHFPKAQVDRQRLGCLIKVWLMIAGFYRRADMWQDSHGALEEAKKLVDSLQAEIAKDTTNAISLTHPGWGGKKSVEELWSDVRSEMAYLFVGEGAPYKARAQFEEALMHYPNHPAAIVGLSNILLDIYGQKLLPTPTIPEMTLPDGEPANLNSGDMTPRCFPIATCQRFRPLRWDSAAITPGAGPVTDHRHASPSMIEELPAPYKAVSLPLVDRLAARDRAYGLLTTLTKLGTGWNYSDAWFALARAHEESGQVDKAKEALWWCVELEEGMGVREWTCVGIGGYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9N5</accession>
    <name>A0ABR1X9N5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002464</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674075.1">
        <property type="nucleotide sequence ID" value="XM_066806779.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039839"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF13">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="548"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="124"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="587"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="653"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="594"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="611"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="676"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="689"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8092103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="724" mass="78633" checksum="18BCBBCA28EBBE7A" modified="2025-10-08" version="1">MTNSFNQKLSALRNSSAWKTGGDKETQQPTLMVRNPPSLVPSPLSRVQTSADIPVNGDSAPARASDAPHVRFNSHAVNGNDHDSNNGAKVDGNNDDDDDRVLIQRVHYASHLATSWTQRKKWCILIVAGLAQLAMNLNTTLYSNAQNGVAAHYGVSTSQAVWGAAAFLITYAFGCELWAPWSEEFGRRRVLQLSMFLVNCFCLLAALAPNFPTLIAARALGGLSTAGGSVTLAMITDMYGPDDPWFQYATNFMSLASLLGSIVGAVAGGFIEANLPWQWCMWIQLLFGGAVQLVHLATVPETRSTVVMDTVAKALRKAVLKSGDENNPMVHVYGPGELGEDGGFSWREYAEAQWRPFGMLLREPIVTALALLSGFSDALIFMFVQSFAIIYGRDASGSGWGFSTIGVSLAFIPIGLGYVICYLSFIPAIRRNTALRTANPASEHAQYEARLWWLNYTAPCLSLGLFVFAFVACFPGVTDHVHWFPSMVASCLIGIANYAIYMATIDYTLRAYGVYAASATGGNGWARDFLAGILTSFAVPLFEKVGKFNMMMILFALALLLTASVYVVYFKGPWLRHRSKFAQTLASRGEEENNNNNNNAADGAAAGVVPETDRGDDVEHGTGSSAAAAPTVVVAAAGGRYNVEYLGKEELPGSRVASRGNTPSHSRRGSVELRQWSRRTSYRPHHQQKQQQQHPQQFTPQISLAEAAERVINDRAAENGNAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9Q5</accession>
    <name>A0ABR1X9Q5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000056</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674144.1">
        <property type="nucleotide sequence ID" value="XM_066804371.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037431"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF7">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="124"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="471"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="585" mass="65004" checksum="59558611AFF00F95" modified="2025-10-08" version="1">MSNISVDSPAQTSFAFPKVHEQLQIINDYFRHIYAQPGSAFLSEVSVTKRCLDGTIDEALLLALCAYTASVLRYPRYYPSQVATWVQKAEDLLWSTMESPTVFRTQALLLAVLCRVETGNFKRGYMLLSMASRSASALRLQYERLDLDHHSQEVRRRLTWSIMMIDNYFSVGLPESGTCPPDFIYLKMPCPEEDFHGDGESGSAPASLDGVSEGGLLQLYIRLSIIRRDVLRLTRNLSLQQVNVMTQITGLVEGMLSSLKSAKPPPYTAEELKRYAHSRWLVRYIAVQISWHQSHCDIYRIFLSGYREAAPDDVIRACTSNYVAQAATSCLRHARALVDIIHDVHDLRLSLLFPPRDICIGGYHASRLLLFLSGSELIPLDQNITTEMATTLARDTLAILQPLFGSSAMLGKTVQELDRIITAYITGTPVYPENACDGDSEGTRRGRPRYAMTIQKHTSLGVHSAFRQAQFHEDDEDARGIGTTGYNNRDTRSSESATTTTTTYPDVSSAPASAQVMMFSEHDQEDLDNSTASGQAVFAAADRSGELVSLGIAPESMDLSALNLNIWSARGWQHDFSPGSSHDCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9R1</accession>
    <name>A0ABR1X9R1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000084</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674172.1">
        <property type="nucleotide sequence ID" value="XM_066804399.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037459"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="25"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="494" mass="52902" checksum="87039EE1DEB17760" modified="2025-10-08" version="1">MDINLTAPNGKNISFSTGLFINNQFVKGSSSESLASIDPATEDPICSVEVATDADVDTAVQAARAAFDNPAWRDLTPEQRAALLHKAADLIEAHKEDLFTLQALDVGKPFPASMHFEAPHTAGCLRYYAGWADKLHGQTVPVSKDKFGYTLRQPVGVCGAITPGTSRSPPRPWKLGPALATGNCVIMKPSEYTPLSALYLAKLFAEAGYPPGVVQVLNGHGRSTGEALVNHPGVDKIAFTGSVATGQRILKLAAGQMKRTTIEAGGKSAFLVFADADLEQAAKWAISGGFGNAGQICSANSRILVQRAVQQQFLDIFSRMARASKVGMPFDASTTQGPQASKMQYNKIMGYIESANQDGAELVMGGGRYQDLGDKGYFVQPTIYKGVTRDMKIFHEEIFGPVLAVTAFETEDEAVALANDSAYGLAAMVFTENIKVAHRTAARLQSGMVYINESNNVDWKLPFRGSKQSGLGSELGESGLDAYLEEKVIHLNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAY7</accession>
    <name>A0ABR1XAY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000439</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674527.1">
        <property type="nucleotide sequence ID" value="XM_066804754.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037814"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06097">
        <property type="entry name" value="Aspergillopepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034163">
        <property type="entry name" value="Aspergillopepsin-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF2">
        <property type="entry name" value="ASPERGILLOPEPSIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046184507" evidence="6">
        <location>
            <begin position="25"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="7">
        <location>
            <begin position="101"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="462" mass="50513" checksum="68BA20D1F98E9DAD" modified="2025-10-08" version="1">MAGFTHVCLVAAMWLTLFSAFVASVPVSEGATFSASVKSSLKRHGHVDPRVQYMRTLAKYNIPIPEKLEKIATSKMAKMAKTKAATPDDVPAVAEEGDMYYLAPVGIGNPPQQLYLDFDTGSSDSWVFSTDTAASEVQGQSIWDPRKSSTAELVPNATWEIIYGDFSSSSGIVYKDTLSLGSSLIINNMTIESAQDVSDTFSKEFKMSGLLGLAWPSIAQTTPPMDVLLDFLPQVLKDPLFTADLRHSSDKGSYNFGYIDHSLHGSEIQYVDVDISEGFWGLQMTGYAISGQDVRYEFSQPKSVIVDTGTTLLYAPESAVEDYFRAVPSANFSEDIYGYILPCNATPPDFIWEIGDPTGERVVGRVPGSYIAFQSLADVVGEDEPMEPWMEGQCYAGLQTLGGFSSPDGILGDVWLKAGFSVFDVGNKKYGSAPKPLDATNKKLGHYRRDKVPFSRKKKIIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBX4</accession>
    <name>A0ABR1XBX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="2">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000826</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674914.1">
        <property type="nucleotide sequence ID" value="XM_066805141.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038201"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06822">
        <property type="entry name" value="PLPDE_III_YBL036c_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00044">
        <property type="entry name" value="YggS family pyridoxal phosphate-dependent enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146:SF14">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine racemase N-terminal" evidence="4">
        <location>
            <begin position="27"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="260" mass="27978" checksum="056356C01AD537E9" modified="2025-10-08" version="1">MANETEMKVDPSRAAALISQLGGISERVAAVAKGRNVRLVAVSKLKPANDILALCQPPTSHLHFGENYAQELSQKAELLPRSIQWHFIGGLQSGHCKNLAKIPNLFCVSSVDSTKKAQVLNEYRGKLLATDPEASKLNIHVQVNTSGEESKSGCPPGEETVALCKLVEEAPHLNLLGLMTIGAIARSVATTAENENEDFTCLREQRDLVVKELGLDRELELSMGMSEDFEGAIAMGSSEVRVGSTIFGTRGPKSEAKITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC16</accession>
    <name>A0ABR1XC16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TBP-associated factor 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674935.1">
        <property type="nucleotide sequence ID" value="XM_066805162.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038222"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="641"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="682" mass="71654" checksum="1B3BD58FB88D00D7" modified="2025-10-08" version="1">MSQPQPSATAPRAFTPQQQAQVHHSPSPTIPNQQVSYPNLQKPPPSRMSPTTASQFSQSFPGASPGAGVPTPGSSTPNGLPSPSLPAHNSPHYGAQASYNQHAQTNGRSTPTLSHAPHPPPMHQTPHHQGQPVGQTPNRPVGLAASHPAHATPNNTHPINTSVSQEPQNSYTNATFTAATPMGPPPATPYTNDAARQAPVIKQAPAKAFAYDMDDTLAGTGINLDEEEQFMNDFESRAGFGAFAPGGRGNFYGAGPASQPVEPSQARTQEELAAEAADRAWNGAAHRLALSRLHDWKEEGFVSPAMLHHRLETIAKANNLELNMDPKPTKEHMPLGRFTQPANLPKPEVKVTTDKAPSGTLVRTVGSIIPKDAYLIDQIALLSLATKERMGELLAEADSIACLRQQTAHGAVPPEWADAALSPSLTQVNSAVSPSTKAQKRPADEMSNGLPTPVSEASPTNPLVDAVVGSGKIVRNAEEARLRKRQKRMDAATDKEKKEDGTTSRSGSVAPGTPGSVAPDAPDSKPLTKKESKKVASKLAEATSSTVNSTLSQFMGGKKKKYSWMTGGGGASGASTPRAGGMSGAPAGGSRGAAKGPLTQGSAHHLGQFRESSAKGKNIQLRDWVHVLEQQRSEQRALQEAYNRMDRSDAGDKAVVPAPTPAPAPASTPAATPAPRKPEQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCR1</accession>
    <name>A0ABR1XCR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001069</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the p23/wos2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675157.1">
        <property type="nucleotide sequence ID" value="XM_066805384.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038444"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06465">
        <property type="entry name" value="p23_hB-ind1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045250">
        <property type="entry name" value="p23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932:SF1">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DAF-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="5"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="198" mass="22192" checksum="3FB346D0885572D8" modified="2025-10-08" version="1">MSQDMLTPEVLWAQRSSNTDPEKNFIYLTIVVPDVKKENLTLDLKSDSLNFKGLSDTKKATYHLELAFFGEVDVENSKINHTSRNIEIKLRKKELKEEYWPRLLKESKKLQFLKTDFDKWVDEDEQNEAPEEDFSNFGGMGAGGGDFGGIDFSKLGGGAAPMGEEDEEEDEEEDDDDMPALEGEEDASADKGKTPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDK1</accession>
    <name>A0ABR1XDK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675482.1">
        <property type="nucleotide sequence ID" value="XM_066805709.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038769"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="79" mass="8771" checksum="C605D4E491EADEF0" modified="2025-10-08" version="1">MARALGVPAPELRSSLEPTIYELRPILDGEHMMLVRFDAAFGFESGRDGDNVQVGQGQGQGQEKMVKRVGLNRLRWLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDT2</accession>
    <name>A0ABR1XDT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inorganic phosphate transport PHO88</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675599.1">
        <property type="nucleotide sequence ID" value="XM_066805826.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038886"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008756">
        <property type="entry name" value="P_tr_PHO88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="192" mass="20951" checksum="5A47878628009E58" modified="2025-10-08" version="1">MFGLSPQIENLVIILGTMQIAKKIPFDDPNVLNMCRALYIVSNLIIAGLYLYVQMKINKNKDMTTLKYVEPAPMGSAEEPKLVTTTIHAYDSAQVKTSFRSQMMGVAMMAGMHLYMKYTNPLIIQSIIPLKTALESNLVKIHVLGHPASGDLKRPFKAAAGLMGGLQQGTPQSDKKAVEAAERAGRGGAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE69</accession>
    <name>A0ABR1XE69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675774.1">
        <property type="nucleotide sequence ID" value="XM_066806001.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039061"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8095001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="284" mass="32854" checksum="7703A6126D917188" modified="2025-10-08" version="1">MMPSSSPPPETARPDDYIRKAWTKDPSVQPFNTEDRGALLDHIYHHSRDPTGFNAVAVLVMAHGESWVRRKVRNEPQPVHLKFEQRRRLLEDGLGAERRRWLWVLPRDVNAWWVFQTKLNDACAKDGFALEFHELLGPDYVKAERPQCHGWHGVVTSNICRPADFDAGKGQALRQMVEFEPWAKERRQLKEQEEGQQAVEERNRATEEDDSDDEVWMCHKQVQGQDYSIRYIRTKHPTLDPDMSSTKLRNIIAASPPENLAENVRGIAMNPELLCQVLQEKTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1USK4</accession>
    <name>A0ABR1USK4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Translation initiation factor SUI1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660445.1">
        <property type="nucleotide sequence ID" value="XM_066819560.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052620"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10388">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="1">
        <location>
            <begin position="36"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="110" mass="12447" checksum="B20AE78CF2080BD0" modified="2025-10-08" version="1">MSIENLKTYDPFADAEADVDAVQLGGKKEDYVHIRIQHVDHGPRPSPKFDRKKILSVIRKKFACNGTIVADENMGEVIQLQGDQRKCMQEFLVGKQGLELDPKIIKIHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT56</accession>
    <name>A0ABR1UT56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_014207</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660709.1">
        <property type="nucleotide sequence ID" value="XM_066818521.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051581"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF92">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="27"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8062110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="274" mass="31013" checksum="5479914240105855" modified="2025-10-08" version="1">MAHFIDGKDVMISEWILLTVALVFVALRIYTRLLRLRQRLDWSDYLLLASAGIALGLIICDTLTYQMGVLDEYETSERLSKISFASNYFYDFGMGFPKLSMLAFYWAFFRSSISPGMRKTLYAITAFVCVCYLTILFDDTFFCGKNVSVQWSQEEGACSVFYAPEPFILNFTLNLTCYLVVYAIPLILLIQGVLASSTGLAVTFVFGTLTIFTTVVRFACLKIGTGQENLHARDGTRHHRRLLLPGLKPLLDRRTRGGSDVDEETVHVNHDQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT98</accession>
    <name>A0ABR1UT98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7702 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660757.1">
        <property type="nucleotide sequence ID" value="XM_066818569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051629"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056119">
        <property type="entry name" value="DUF7702"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G00100)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109">
        <property type="entry name" value="UNPLACED GENOMIC SCAFFOLD UM_SCAF_CONTIG_1.265, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24800">
        <property type="entry name" value="DUF7702"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7702" evidence="2">
        <location>
            <begin position="6"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7702" evidence="2">
        <location>
            <begin position="192"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="27585" checksum="68EB5D5329773CBF" modified="2025-10-08" version="1">MTTDALPTVTLAIYAVLSIPVLFCLVRHGRTGLVGWFYLLVFCTLRIVGGALAMNSNKNSSSASLIANIGLSPLLLAASGILHEGRAYYVADGANKKTEWLLVLVFHAIVAPGVALLAAGASGLQSATATKTDLVLVSVGIALLTAAWVVLCIWTALSFLPSSSFVFGRRRQGTTKVMMDKTSPAAAARGYGTKILWGVAAALTFIGIRVFYSLVALTTRLAYLSPSTGALSIRVVVVFLPELVACLILIVAGFMTRHVASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTG9</accession>
    <name>A0ABR1UTG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660835.1">
        <property type="nucleotide sequence ID" value="XM_066818647.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051707"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="107" mass="11523" checksum="8B203A9DDB2BFCC5" modified="2025-10-08" version="1">MVASSIVAPDRNEASNHLLSRAAEESRNGLAPGALIESWPNSPHSIISALRVVRGLMRNNQHVDSVFCKRDDEMILNIGPVGDGEQVVCAFIKKKEPPSPAAQQLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTJ4</accession>
    <name>A0ABR1UTJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014332</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660834.1">
        <property type="nucleotide sequence ID" value="XM_066818646.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051706"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="578" mass="66499" checksum="DE64A8D376E9E725" modified="2025-10-08" version="1">MFTLPDDPYARLGVSKDAQIPEIRSAHRKLVLRCHPDKVADPEQKAIKQEEFQKVQRAYEMLSDSKERQKYDDMVHANEMEKQNARIRAEQPAYSSRSAPRRENTTESHHYNVNVRMAEPRFERSASAYAPSPKPAPAYTSGRTPPRYEENPYSSSYDDGREHRSSRKAAGPSSYEREAPSSRRAEEDKRSRKEADKAWERQREKAEKDSSRRKAEEKERDRREKEKEKDRRKKKEEASQKERKHTDEKRHHRTPYSEDEPVVVEAVHKSEKSSSKTKANIRAKVVEAAPIREAITEDRHRSKQDAHLEFAAHYLQTSRSKVAPGLSRAKTYHPTSGWTPPVPTPPPAVGAMAPPPPPIPEDDELPKRSSAARRSSHDTPRSKLSSSHRKSSRTEEEPRVIPGLKKFSTMPSRHSPPELPVRLLGPHPGLSRAQTWYSAAPAEEDYRDRGRSKHHPRYHSDEDYDDYSEDDARYSRRPSRHHSPEAPKTKFRYTVEGSKAIPVRTRAESPGRRGYKVPYYGHEANSGRPVASYESYDQQPAYFPKVKYAPKYGEHDVAYSTTSEAGYRMTEPPQVYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTP0</accession>
    <name>A0ABR1UTP0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carotenoid cleavage dioxygenase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660902.1">
        <property type="nucleotide sequence ID" value="XM_066818714.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051774"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF24">
        <property type="entry name" value="CAROTENOID ISOMEROOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="411"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="571" mass="63195" checksum="24A6ED6463A9B041" modified="2025-10-08" version="1">MALNGGQGLPNGSPFRKGPQDEDEDYESNVQKMLDQNFDDWPNEAGFEGLTEVKGPVDLKVQGSIPTWAAGTLYRTGPGGFEVKTALNSTYRVSHWFDGFGQSHRFTIVPDENGTVGVEYASRCQTEDLVEEIRQNGRPNGFTFAQRQDPCIGLFGKVMTQMCRASGAPRASTSAQQPSAGHRATATNLWLTTDSCNLKEMDLQTLEPIGFAAQQKLHPLLKGPLSCAHAQRDPATGDLYNYNLDFGPVATYRVFRVNAATGTTDIIATIRQADAKPAYMHSFFLSESFLVLCIPSTHLATMGLHIPWQRNIVDALEPFDESKTCKWFVIDRKGGRGVVATYESPAGFHFHSVNAFEETDEETGEMLVYCDVIEYPSLDIIRSFELDVLMRRDGGAAEFWGDEKRNRNTQSRFARHKFRVPSQKSNSKGGGSSSSSTPAKSEKVLEIKAPRVGELPTINPAYATRRYRYFYSLPNRGQSTLLDGLGKTDLETRETVYWDNPRGHTPGEAIFVARPGNAVDEDDGVLLSVVLDGYGRNSYLLCLDARTMKELGRAECGWAIAHGFHGIHTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUP2</accession>
    <name>A0ABR1UUP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">small monomeric GTPase</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014704</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661206.1">
        <property type="nucleotide sequence ID" value="XM_066819018.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052078"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051065">
        <property type="entry name" value="Ras-related_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45704">
        <property type="entry name" value="RAS-LIKE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="110" mass="12497" checksum="82CB50189CF56DCB" modified="2025-10-08" version="1">MLREERVGKTALTTRFLSQRFFETKTRTYPIPILLIGNKRDLESGREVSIHEGRALAQELRCGFIETSARDDDNVEKVFYTMVGILRRQAVAAAEQQGSKSGIENFCAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWH6</accession>
    <name>A0ABR1UWH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-binding oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_015119</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661621.1">
        <property type="nucleotide sequence ID" value="XM_066819433.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052493"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="45"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8063022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="398" mass="42845" checksum="1A4773FE66F060DE" modified="2025-10-08" version="1">MPCYAVATSFESVCQSLEASYSLDVVLPSDSNYANLSEENWSQTTWKTPACILRPESAEQIATVLPQLVAGNISFAVRSGGHLPSPGAANIDKGVLIDLSKFDHVTFDAEKEAASIGAGQRWLNVYTQLDKYNVTVVGGRVTDVGVGGLTLGNLFWALKGGINNFGIVTSMVLRTYPIRQVWAGVKGYAVEQIPALFDALLEYQSTPNKDPYANLMIQGFATNASLGVAHSSSLTLSRIDQRATSFKPDAALYKKIANIAAHSPHLDAIRSAAAGSQAFGLQPISASLVEAGRARGGGNALGLEAANQTWMVLTSGWWSAEDDAVVHGATRSMVDDIESASRRARRYVEYIFMNDAGADQAVIAHYGARNVARLRGCRRRMILAWSFRRLVPGGFKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3B7</accession>
    <name>A0ABR1V3B7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662405.1">
        <property type="nucleotide sequence ID" value="XM_066816713.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049773"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="395" mass="43708" checksum="3B658D93661956C7" modified="2025-10-08" version="1">MRDVRGGRDTGRGRPRHRRNGPWKDGRQQDDDLESEADDDVDFLSDPALPPLFAEEDDDPVDDLPPVPHNPITRLLRKHQAQQNTSRNNRHRGNSKNNPFLKQQQPHQQQQQSNLNLPSFQRQRQQQQPQYKQKRYPQRSNSKYGCNDCNDCRAVRKANVRLRNALHNHLVASAATIVEWSEEVGVPFGGGADDEMDWQPEPEIRVIVVQQQQPDDRRHNYYYYNNTFGNFLPNVFPSTRYGGPGGYRRHGVYGGSGGYERNGRGGPGLSSGHSGVGAATAPWCQQPGIDSLEEDQGTEDPLEEPPEEPYQSMALEPDPFRETPSGSGFANTSGVSPLGKSANQLNSSSGVVANHSAVSSSGILASMITNVPSIEVGEWSQPNAGNQGGFNGHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3P8</accession>
    <name>A0ABR1V3P8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662568.1">
        <property type="nucleotide sequence ID" value="XM_066816876.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049936"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="35701" checksum="4FA04FF39A42B411" modified="2025-10-08" version="1">MIETFSRCFNTFHGEDPFQFLQAVVYKYGIPKPAPAPFRWEFSIGDLPEDLLWWGDVVPTMASILDALLSPSHTIDWRRDNLMSWLHWDGEKVFLSSHWHSIKPLTSGGGDATRSRHRHFSSIGREPRGFEIKCARYNEPLILLAYPENRDPEADRLFSVLRGASVTGTPTFLGAGIGNKPWHYDPPPLQCSCPSYIYDKRGELMGRGIVDDPGWFVAELERIAAKEQQEIDENVRRGVKYPRRLRNRRIFMLAFIERESLELRAASMPPLPWETEPVSWTSAHGGSRSFRARQGGSGGQLWIDTAHLECWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V476</accession>
    <name>A0ABR1V476_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662752.1">
        <property type="nucleotide sequence ID" value="XM_066817060.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050120"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="67" mass="6462" checksum="91C70FF4E44AEE67" modified="2025-10-08" version="1">MGCCRGNVKKSQTPASGPKLGELAKEKTSASLWGAPAASTPKPAQPTSGAANSSTGAGGSGFDDLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V527</accession>
    <name>A0ABR1V527_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EVE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013028</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663034.1">
        <property type="nucleotide sequence ID" value="XM_066817342.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050402"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21133">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052181">
        <property type="entry name" value="5hmC_binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047197">
        <property type="entry name" value="THYN1-like_EVE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14087">
        <property type="entry name" value="THYMOCYTE NUCLEAR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14087:SF7">
        <property type="entry name" value="THYMOCYTE NUCLEAR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="4">
        <location>
            <begin position="101"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="271" mass="29649" checksum="FAFA87770A57A323" modified="2025-10-08" version="1">MPPKRKAPPPAEDEVAAESSNLRRSTRRKPSAPVDATKAATTTTAPAAKSKTSTTEEKSAKSDTQPNGTPDSTKPAKVTQKESTSETNSGAGSSDPSCEKAYWLLKAEPETRLENGVDVRFSIDDLASRTEPEPWDGIRNYAARNNLRAMKKGDLAFFYHSNCKEPGIVGTMEIVREHSPDLSAHDPKAPYYDASSKPSEPKWSVVHVEFRSKFAQQMGLKELREMGKPGQPLEKMQLLKQSRLSVSRVSPAEFKYLIGVAAARGGMSKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5P5</accession>
    <name>A0ABR1V5P5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Amine oxidase</fullName>
            <ecNumber evidence="12">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_013273</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16153"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:228804"/>
            <dbReference type="EC" id="1.4.3.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="12">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="12">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="12">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="12"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663279.1">
        <property type="nucleotide sequence ID" value="XM_066817587.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050647"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049947">
        <property type="entry name" value="Cu_Am_Ox_Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008559">
        <property type="entry name" value="PRK11504.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF86">
        <property type="entry name" value="COPPER AMINE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01165">
        <property type="entry name" value="COPPER_AMINE_OXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="14">
        <location>
            <begin position="11"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase N3-terminal" evidence="15">
        <location>
            <begin position="101"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="13">
        <location>
            <begin position="228"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8066526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="686" mass="76769" checksum="C30053C3F464758B" modified="2025-10-08" version="1">MVSAVANPDLHPFDPLTAGEIEAAISIVKKAHGEVLFNVVSLHEPRKAEMMKWLQDSANLPKPDRIADVVVIAPGGKVYDGLVDLKTGTITKWELLEGLQPIITMEELQAVEHVCRKDPKVIEQCEISGIPKEDMHKVYCDPWTIGYDERHGNTIRLQQALMYYRPNPDDCQYAYPLDFCPIYDGEKKAIIDIDIPKVRRPLNKAPPVNYHPAAIENAGGYRTNLKPINITQPEGVSFEMKGRTLEWQNWKFHIGFNYREGIVFNDITYNDKGTVRPIFYRLSLSEMVVPYGNPEHPHQRKHAFDLGEYGAGYMTNSLSLGCDCKGSIHYLDAEFPSREGGIRTIKNAVCIHEEDAGILFKHTDFRDESTIVTRARKLVVQQVFTAANYEYAIQWIFHQDGTIQPEIKLTGILNTYAMNEDEDLGGWGTQVYPGVNAQNHQHLFCLRIDANVDGPNNTIFMSDAMPSEAPVGSKENFYGNAFYAKRTKLATTGQAATPYNGDTARTWDICNTNRLHPYSGKPASYKLVSREVPRLMPKEGSLVWKRAGFARNAVHVTKYSDDQLWAAGRHVPQTSGEPSHGIPEWMGDGTESIDNTNVVLWHTFGVVHFPAPEDFPVMPVEPITLILKPRNFFDNNPVMDVPPSYASTPSQVTANNAGVYDATDKISKLAFGKECCSNGTNGVNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V644</accession>
    <name>A0ABR1V644_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_013129</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663135.1">
        <property type="nucleotide sequence ID" value="XM_066817443.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050503"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.690">
        <property type="entry name" value="Importin-alpha, importin-beta-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032413">
        <property type="entry name" value="Arm_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002652">
        <property type="entry name" value="Importin-a_IBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036975">
        <property type="entry name" value="Importin-a_IBB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024931">
        <property type="entry name" value="Importin_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16186">
        <property type="entry name" value="Arm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01749">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005673">
        <property type="entry name" value="Importin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51214">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IBB" evidence="9">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="124"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="166"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="337"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="553" mass="60286" checksum="6D6B5DB022E48B31" modified="2025-10-08" version="1">MADRYIPEHRRTQFKAKSTFKPEELRRRREEQQVEIRKAKREENLAKRRGIGTGENRPGASLGAAPDSDDDTAPTESQLNEDLPQMVQGVFSEQIDLQIQATTKFRKLLSKERNPPIEEVIKTGVVSRFVEFLRSPHTLVQFEAAWALTNIASGSATQTQVVIEAGAVPIFVELLASPEPDVREQAVWALGNIAGDSPTCRDYVLGCGALKPLLNLLGDSRKLNPQPDWSTVSPEDESFLEDGISNCDGQIAPALPVLAKLVYSLDDEVLIDACWAISYLSDGSNDKIQAVIEAGIPRRLVELLMHASTSVQTPALRSVGNIVTGDDVQTQVIINCGALPCLLSLLSSNKDGIRKEACWTISNITAGNSQQIQSVIDANIIPPLIHLLSNGDLKTRKEACWAISNATSGGLQKPEQIRYLVAQNCIRPLCDLLACPDNKIIQVALDGLENILKVGDLDKQAAGEGAESINRYALFIEECGGMEKIHDCQNNANEEIYMKSYNIIEKYFSDEDENADEAMAPQAQGANGTFGFGTNGAQGGGFNFANGNDSMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V757</accession>
    <name>A0ABR1V757_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Magnesium chelatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663790.1">
        <property type="nucleotide sequence ID" value="XM_066818098.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051158"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.80">
        <property type="entry name" value="Magnesium chelatase subunit I, C-Terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052041">
        <property type="entry name" value="Nucleic_acid_metab_PIN/TRAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11603">
        <property type="entry name" value="AAA FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11603:SF132">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="52923" checksum="68F888A94FBE3FC0" modified="2025-10-08" version="1">MADEELLQKIHGLGDLDLAALLCLMSREHCIISTEPESLDDLVEELQLVVAQTFNLKSAVVNCTAQTTLDDFAASILLPQSPTASANSRSSSPVLTRGNHQQGTNDSYFHNNNRSTRANHHHNNSNGGGGGLRALTPLPATSYSHNQHYQSGGSHTQPQIANVVLARNLDRAPKAVQIQALELLRTRRIFTRTSVQAVPKQFLFIAVLGADSAGQARVTEHLNDFFYIAHWHDPEDGFARLDDRDENNPNPDTGNNVNGDADSMRDYEGDIYHSSSESLSGESVVRRRSLRGSMSSAQYFAAPSSNPYEAAPAAAPAAAQPSLARAATIKSAKSRAQPHPIRTDLPPSYSSPFPNFTEGDIAALATASRQVHVDIEVLRYQMNIISHLRMHRAVAAGCGSGNGITPVATKYFDQLVKSLAALHGLDYVTPALVVLAAKKIYLHRIRIVPPDKERSMQWGSDLAAVEQLLEGIGPEDVVEDVIGLVASAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7V1</accession>
    <name>A0ABR1V7V1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664037.1">
        <property type="nucleotide sequence ID" value="XM_066818345.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051405"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045594406" description="AA1-like domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="14875" checksum="E914DC2B129A96E4" modified="2025-10-08" version="1">MKLFAALFLFSSTLVAAAPTSDTVTISDFMYAAPANGLTVDGQHVDRYMRFKLSVDDITCQALDVDIPATGYTCDDPAYTFDTLDPGVLDATFLIRLYRSVGDDDGSKLSGDFRIIATGPLFTGKVQVGTTTGTLEPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7W3</accession>
    <name>A0ABR1V7W3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-lactamase-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664006.1">
        <property type="nucleotide sequence ID" value="XM_066818314.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051374"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058664">
        <property type="entry name" value="ARB_00930-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF97">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26335">
        <property type="entry name" value="ARB_00930_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045672927" evidence="2">
        <location>
            <begin position="24"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="105"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-like ARB-00930-like C-terminal" evidence="4">
        <location>
            <begin position="437"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8067253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="587" mass="63211" checksum="3D591DB79587DE20" modified="2025-10-08" version="1">MKIPTSIRKAPLVWSLLLRLAAAAAPDCPFPGPAFPKPTALASSETFKSVLANLTETFEARDQDRANNPNGTSWSVQVFSVSDKDSNSPLWEYHHSAPSLATSNTGGVKEVNGDTIYRLGSLTKIFTILTFLVEAGDGYWNTPATKFVPELALLADKYQYDPVMNVDWGSITLGELASHTAGIVRDYALLGELTQENNQTVLESQGFPPAPANETPICGEYFLCNRNQLFDGLGNVPPSFSTSWTVGYSNVGYQILAYVLEAITGKTFAAMVQSDVIDKLGLAHTYYQKPPDNLGIIKVVIDRSFISQHRQHVLLRQRPLHPRPRHPQQPPDPERADATLAQARDPDVGLARGGQLPLGPEADPLSSTTGGGGGSSRITDAYNKAGSINAYQSLIILLPDYDVGITALLAGGWPGNANWNMADAIGETLVPALEEAARLEADATYSGTYSANSSASLNSTIVLSTESGRPGLGIDRWVSNGTDMVPVAIRYTLNYNVTGPSLRLYPTGLEKRNDDGSRKVAFKAMIQDRGATDHAADMFSTNCGTWVGQTTAVYASMPLDQFVFHIDDGGGVKSIESLALRAVLDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8R6</accession>
    <name>A0ABR1V8R6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663207.1">
        <property type="nucleotide sequence ID" value="XM_066817515.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050575"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022190">
        <property type="entry name" value="DUF3716"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12511">
        <property type="entry name" value="DUF3716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="256" mass="27728" checksum="158E88A651650D94" modified="2025-10-08" version="1">MHTTQNIRAILARATGDAHDPPNACNRCSNGAGVWEECVTVIPTLSRDPLNGACANCFFYSRGHLCSLRNSKPKTSIRPRLGEDSKDENKSENDENDSEGDGVDGAGDEVNKANEVIKVNEVIELGDKPLCRYKTTLLKMRELAATVQASIGKLHPLCSLVASREKRLVMKFAKGSTLEDSLASRNTPAFQTIDNEAKIAGNAIGELASLVRCLMVDETEEQVSFDDGSRAPVLTELAPPRSEYHPGSPSIGHTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8Y1</accession>
    <name>A0ABR1V8Y1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF2278 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663176.1">
        <property type="nucleotide sequence ID" value="XM_066817484.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050544"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019268">
        <property type="entry name" value="DUF2278"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10042">
        <property type="entry name" value="DUF2278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="24641" checksum="66C1F53B5D4C87B8" modified="2025-10-08" version="1">MPISRYGVWRGTATKWEPTEQDNDHGHITFTDGKELDLDCAVDVKSKDHDSRIVFWDVTSFDKTHPVAQRLSQLKPGYQAITDHAAHGLGLDYYRSQLVKPQQGRILPYNKNGPDNDILDFLNPILNAAVEQKADMYLFGSKYDGNNGDGIHDIHMNQGDVGHFAKENGVYQDGGMIFNFKTGSGEVEGWQGVFLAFATQATQTDSKGNAMGPTFAQILGTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V929</accession>
    <name>A0ABR1V929_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phenolic acid decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663221.1">
        <property type="nucleotide sequence ID" value="XM_066817529.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050589"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008729">
        <property type="entry name" value="PA_de_COase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40087">
        <property type="entry name" value="PHENOLIC ACID DECARBOXYLASE PADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40087:SF1">
        <property type="entry name" value="PHENOLIC ACID DECARBOXYLASE PADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05870">
        <property type="entry name" value="PA_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="20231" checksum="B5BF046593C4EBAA" modified="2025-10-08" version="1">MPLVGNVSTASFDEDIRDRHLLYSYAVPGSETESGKPETWRYEMWFFNEDRIVYAIHGGPMAGRKNYQAVTYQCVRPGELWQCSWLEETGTLVSMVYDIKEKRISTMIGFSKGHWEKSVDAHGDKRNPEDLARWRQLAQLGCQTDRTMLVEQAELEEDFRGAGDLEPIEMDWPCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIJ6</accession>
    <name>A0ABR1VIJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NOL1/NOP2/Sun domain family member 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_011269</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a cytidine in rRNA + S-adenosyl-L-methionine = a 5-methylcytidine in rRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61484"/>
            <dbReference type="Rhea" id="RHEA-COMP:15836"/>
            <dbReference type="Rhea" id="RHEA-COMP:15837"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74483"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664874.1">
        <property type="nucleotide sequence ID" value="XM_066815584.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048644"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF3">
        <property type="entry name" value="5-METHYLCYTOSINE RRNA METHYLTRANSFERASE NSUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="13">
        <location>
            <begin position="149"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="65"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="171"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8071066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="407" mass="44346" checksum="636C20803F90AD0E" modified="2025-10-08" version="1">MPGLTKAQLKLVEASEHSFDRTYAAQYGEERWKNSLRPALLKNTRYAMLVNRYQAAEIPSGGVFTDGDRENLQPIDFFPPPNGKDSVSPNSTVNPEAPRLIAYKRGDKIDPSQQQQQQQPISADEPFPPPQVTIAQGGSKGLMTHWNLDAASLLPVRLLNPVPGDKVLDLCAAPGGKSLALAQLLLPPTFDGSDAPTLAGGCLHSNEMDGARNKRLAANLEAYLPPALFQRGEVKVLKLDGSDPLAVLSLPQRAGGYDKVLLDAPCSSERHVLHAHARARQAGKIADEMALWRLGQSKKMAKIQAALLMTALRAVKVGGRVVYATCSLSSEENDGVIEKGKELVQKDRKKLGIKWDVKVVRSNDAGEEEMLDSWAERTKHGWVVLPDHPSGGRWGPLFFAILEKIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIN0</accession>
    <name>A0ABR1VIN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664800.1">
        <property type="nucleotide sequence ID" value="XM_066815510.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048570"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="348" mass="38348" checksum="2429D15795998C48" modified="2025-10-08" version="1">MPAQQARFATYTHNRCCSGHGGRQGSDLISLQELDFAGCNVLGGSERARRRNVILPARLRVQQYCEVPWPRNASCGESRTEKDRIAQNSQERTTGLLPTRVMRVWKGGGGSLPSLQGGEERDSTDRQTDSENPLRPPSHSDRIAVLWQGHHPHMYRKKVEEGLWGNHPGFRFNTHLYTTRTYTTTHRIFGWRVVLGLTKQTPDCGSFSKQGRREGGGRGGVSAATRDGGWCRGERTSLPAQPASKGRKEGEGEDEKSSSSSVHIQATRAALCAACSVQRAFTETSFAIGTVASSAVLKSLHPSPVLDDARFRRKDLPLGTLGRVPRAYEMFGTHTSLLPCYTLTPLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ40</accession>
    <name>A0ABR1VJ40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665060.1">
        <property type="nucleotide sequence ID" value="XM_066815770.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048830"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="73" mass="7970" checksum="CDF97ACC97139C6A" modified="2025-10-08" version="1">MPLSPLSALSTKCATTALCYLRSISLWGVVIVLFLFGIVRARATSIFERSNTQPPPPTRSTTTPPPTDTKKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ78</accession>
    <name>A0ABR1VJ78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665098.1">
        <property type="nucleotide sequence ID" value="XM_066815808.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048868"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040586">
        <property type="entry name" value="FxSxx_TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="852" mass="96313" checksum="7001D3954C57C469" modified="2025-10-08" version="1">MSDSVRERPTASQQQFGNATATDGSQVFQGSASGNVTMNLTHNHHYSAPERPETPPKPTAIIPFNRDRDFVQRDTILDQVHRSCSDPASRTALVGLGGVGKSQIAIEYAYRVREQSPETWVFWVHASNPARYEQSFRDIADYLKLPERKNSQSNIFQLLYNWLRGEKSGRWILILDNVDAAGFLLHNPPDHDGQRDGSDSRSQPLVSYLPTCQHGSTLITTRSRDVASKLAESRNTITVDPMNQAEAITLAKEKLGKPDRQGDIEAIESLVDTLEYMPLAIVQATAYISQKAPRCSVRQYLEKFTQSDRKRATLLDYEAGQLRRDGEAKNSIIITWQISFDHIRQTRPSAADLLSLMSFCDRQGIPESLLRASDEKEGATSRPAQYRRSPALGGLGSDQESSDEDVELDSSIDDEDEFETDVSSLRDYSFISAVGDGKTFEMHSLVQLATKRWLEAEGQQEKWKSEFIHRLDVQLPTGAYENWATCRALLPHTVSAAAQRPKDEASSKDWLRSFIKLHGIFGSWGEGMKRRRWPRMRRSSELRYLGGRKKKGHWEAAEKLFMEVMETRKQKLGPDHPSTLTSMANLASTYRNQGRWEAAEKLEVEVMETRKQKLGPDHPSTLTSMANLASTYRNQGRWEAAEKLEVEVMETRKQKLGPDYPDTLTSMANLASTYRNQGRWEAAEKLEVEVMETSKQKLGPDHPSTLTSMANLASTFWNQGRWEAAEKLDVEVMETSKQKLGPDHPSTLTSMANLASTFWNQGRWEAAEKLDVEVMETSKQKLGPDHPSTLTSMNNLAYTLEAQGRQSDALELMRECVRIRRDVLGARHPHYLSSLETLRAWELEHTDTITTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VK24</accession>
    <name>A0ABR1VK24_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664388.1">
        <property type="nucleotide sequence ID" value="XM_066815098.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048158"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="99" mass="10870" checksum="FBB73C9D03A73823" modified="2025-10-08" version="1">MSQQAGPTNRPQPAKDACAGGNIAGGANSVPVTRNQRTFINAVRAGLAGAFLYAIWRPSAAEFCNAWPGWTWRAVPNILWEVTDRVLDRFPWMLDLGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKA2</accession>
    <name>A0ABR1VKA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664177.1">
        <property type="nucleotide sequence ID" value="XM_066814887.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047947"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="319" mass="34223" checksum="2E61D9845CF993B4" modified="2025-10-08" version="1">MLALIEGRSGIPRVEWRAMQLIKICQRLSSFLRYISRNIRTDINRPDVYTQLDRDRSEHHVLSVVAGIRIGQHQLQGGISYIGRIPHKRPLAELARVLVRPRVRAREHALAVELADGLDDGDDFLGQALRRSAVDGVLKGRLNPLELVAVGDARDVVVLAGDAVLVAVERARDGLGPVAHDDVIALHARSVLVEADPRARVVRGLEEERLQRLRLRLLDDRRCRCDGLAGDGGDDGRGRAGDGGGRALAQGRRLRRRDSGRGGGAGLEERGGRRGHRDGGGGGAAADGGGHSRGDGCCARGLHVEACAAGEVLVHGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKV0</accession>
    <name>A0ABR1VKV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010767</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664372.1">
        <property type="nucleotide sequence ID" value="XM_066815082.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048142"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="152" mass="17064" checksum="BF84F49D6FD7E230" modified="2025-10-08" version="1">MDEVSNCYCAICGGPLSDSAFHEARLGREESIDWIKGVWVLQREHALDNWPTKALVSGGGSYDGNHVWVSYQRGYFGGRLSCRLYRDLDSRRPAIPFHQPCYLLLTLALFGGHRAVSEKDTDALFTTMQSLTTYSAAHLELDYGFGGKDPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLK1</accession>
    <name>A0ABR1VLK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin-related protein 2/3 complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011007</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ARPC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664612.1">
        <property type="nucleotide sequence ID" value="XM_066815322.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048382"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008384">
        <property type="entry name" value="ARPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629">
        <property type="entry name" value="ARP2/3 COMPLEX 20 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05856">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039100">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="169" mass="19573" checksum="3E354CFD228AA224" modified="2025-10-08" version="1">MSQSLRPYLKCVRSSVTAALCLANFASQTSERHNVPEVEAQTSPEVLLNPLVIARNENERVLIEPSVNSVRISIKIKQADEIENILVHKFTRFLTQRAEAFFILRRKPVKGYDISFLITNFHTEEMLKHKLVDFIIQFMEEVDKEISEMKLFLNARARFVAESFLTPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLZ6</accession>
    <name>A0ABR1VLZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665048.1">
        <property type="nucleotide sequence ID" value="XM_066815758.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048818"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="240" mass="27327" checksum="75A73EAFF64DD7C9" modified="2025-10-08" version="1">MNQDKESRFARYARYFTNEKALANPSYANDTILQAYMSSDESMVYIRHHEEKSDCDKSDSGGEVEENMVREKEILPTVAEFREAESDSDQVDSGSWLFDTHSQTDTESESDGEQEPCPCMIHTPEFEGKLLSAVAGLIDSQFRAEIPQVVDKAVQETTEELHKIAQDAAREEIGKYIMGIHPNDSGDEELALAQFIENRLKEFDEETLERVYMQRSMVAVLKRLVEKAESDLALLEWGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT40</accession>
    <name>A0ABR1VT40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665371.1">
        <property type="nucleotide sequence ID" value="XM_066813409.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046469"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="230" mass="24398" checksum="353110D146FB8611" modified="2025-10-08" version="1">MSPITAFQCAKDLGLWLGALVLIDACARPLFVARSSNIQTMYTTVLFTPSYSSPLYSGSDSAPSSSSTRPGPWSSEGGSCGGPSSCTCVSSWPTCRGWSSTGSGPGSASTSSPACHPAAPGPPARAQQAARVLVGREAVRRDEQEPVPAGRQRPPGEDALGGHVRENLAADQDRKQPRVVARLESHHDVLERNHGLERHHGGCKRRRVNDGDVLLEPTLTATGRRFYSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV88</accession>
    <name>A0ABR1VV88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Betaine lipid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666098.1">
        <property type="nucleotide sequence ID" value="XM_066814136.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047196"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021829">
        <property type="entry name" value="DUF3419"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473">
        <property type="entry name" value="BTA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11899">
        <property type="entry name" value="DUF3419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="818"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="838" mass="94325" checksum="34DA58DC73867A2E" modified="2025-10-08" version="1">MAFPGGNMLPIDPQTKLYLAGLAGVSFLGICLSSILTKPKKHDENPGLARALWLFVYGCFLKPHSVGEKGNQQDALESFYKTQAGAYDVTRGALLKGREDMLALAAAQLVYRAKQDGGSSEHKRRIWVDVGGGTGFNIEAMAKFVDVPNFFSSVYLVDFSPSLCEVARKRFARLGWDNVKVVCDDARKFRLEDHEPSLGGRAPKSPDISYFSKQRPEHGGADLITMSYSLSMIPDYYSVIDSLPSLLAPQGIVGVVDFYVQSSVDVSFRNYTGGVTDRHVNFIPRTFWRAWFDIDRVALEPGRRDFLEYRFGTVLNVNNRNSALGYIPYYIWVGTHKRPMSSSLPHEIVEKVDALVTESPYLHPKNHSNALSRAVERAAPEIHSKAFDAAVVNLSANLPLPSFFYQNHHWRIYYDDQLKKHTQFNDEYIYAFTWEDTRVDERILNLKSDDVVLCICSAGDNVLSYALQSPARIHVVDLNPTQNHLLELKLAAFSSLEYEDFWKIFGEGKHPEFRSLLISKMSPHLSSRAFQYWLSNHHIFTKSKGGLYDTGGSKYGIRIFRWITRVFGCRSAVKALLASKTLNEQREIWRNKIRPALLSRLVSRFVVSQESFLWTALGVPKNQLAVIEADHAVSDVVTGPKPTAKNTRSHAIWHFMVDTLDPMVESTHIPGDNPYYLVCLDGKFSKKCHPDYLSPQAHARLSRKGAFDGLRIHTDEIDEVIARIAPGTLTVAVVMDSMDWFDPETDAAARQIRKLNRALKMGGRVMLRSAGLKPWYVEVFEEHGFSAKCHGSRKGGKCIDRVNMYASCWIMTKASNLAPPTPGPDSSFEATDMEPLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVF3</accession>
    <name>A0ABR1VVF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA repair exonuclease rad1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_009889</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OST5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the rad1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666166.1">
        <property type="nucleotide sequence ID" value="XM_066814204.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047264"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003011">
        <property type="entry name" value="Cell_cycle_checkpoint_Rad1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003021">
        <property type="entry name" value="Rad1_Rec1_Rad17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007915">
        <property type="entry name" value="TMEM258/Ost5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05251">
        <property type="entry name" value="Ost5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02144">
        <property type="entry name" value="Rad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01245">
        <property type="entry name" value="RAD1REC1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01246">
        <property type="entry name" value="RAD1REPAIR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8075226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="41716" checksum="BA4A0F16A867114C" modified="2025-10-08" version="1">MDSQLREIWATAPGTPFQPTVGKDTQFTVAFTLLLLGVALFGGFALNRSFINIPLLGVPASLALAVGTVYMFCAPPLFKAIASSTRQIYQLLKCISFTAKVHVQITQDGIRFAADHSRVMQGRIPIGGCLLKVQETKTERSPQFQINLAAFLEALQIFGASDVAAKQAKADAEPYRSNLRNYRPDAFSHQTLGVPGTCCLLYEEDGSPLSIILEETGVKTRCNMVTYTPEQPDDIPFDRDDLAFKIIMHSKWLLDSLSELAPMSPTRITISASPNAPYLALSSGGALGSASVDFTSGRDLLDTFTIDTKWTQSFKFDLVKSATEAMRVASKVSFRGDGQGVLSLQFMVEVEGGTTSFLDFRFVPYIAQDDDEIDTDEEEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW52</accession>
    <name>A0ABR1VW52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666007.1">
        <property type="nucleotide sequence ID" value="XM_066814045.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047105"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF79">
        <property type="entry name" value="HSP70 FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="685" mass="75271" checksum="52E564ECBEB2A0D3" modified="2025-10-08" version="1">MNHPGAGPRPPSYTANFNPGGPPPPVGRMSPQTVQGPARTPPSQMVGGPPPINTGAPVQGYPPQMQMQPGGPPPIQGGPPGYAGATGYPPPAPPQNQGPAMQQFGRPAAEVEGNSRSKAQLIVGIDFGTTFSGVAFAFATNNEAKEDIITEWPGAGSYTKQKIPTVLYYDQYQKVVGWGPDIADALAPTGYPKPGVQKVEWFKLQLMLSGNTYIDPINLPPLPPGKSEIDVAADYLFKLRQAMRAALQKTLGEVFNREERNIRYYLTVPAIWNDAGKAATRAAAIQAGFLRDENDNRLTLVSEPEAAALFCSKTGLLNIKVHDAVLIVDCGGGTVDLIAYEVEDENPFTVAECTAGSGDSCGSTALNRNFSNILRTKIRKMKLPDGSKTAGRVYAKCIMDFENRIKADFRNNGQKWAVDVGIEAEFPEAGIEEGYMTFTNEEILQCFEPVVNRILELVRNQIIAIQAQNRTLQNILVVGGFGASEYLFQQIKLHVPPQFQAKVVRPMDSVAAIVKGAVTAGITERVVTHRVARRHYLMATLQPFKEGYHPEAYRVPSLDGKDRCKFTRQIFVQKGQKVKIGEPVKVSFFRQVAPGATLMYEDILYACDDDVCPEYTKDPRIKEVVTLTSDLSRKNLEKDFERMDTPQGTFYRVYFDIYLTLDGSEFSAELVCQGEVMGRCRARFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW96</accession>
    <name>A0ABR1VW96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase kappa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010198</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666475.1">
        <property type="nucleotide sequence ID" value="XM_066814513.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047573"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03586">
        <property type="entry name" value="PolY_Pol_IV_kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050116">
        <property type="entry name" value="DNA_polymerase-Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022880">
        <property type="entry name" value="DNApol_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002677">
        <property type="entry name" value="PRK02406.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076:SF33">
        <property type="entry name" value="DNA POLYMERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076">
        <property type="entry name" value="DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UmuC" evidence="5">
        <location>
            <begin position="123"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="475"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="526"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="599"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="539"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="603"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8075535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="652" mass="73014" checksum="8B4ABF9AE54EDFF4" modified="2025-10-08" version="1">MAEPPNPPTTNPRDDDDDQQKAATAAAIAEHGTLKYSLLGPSLTKAGQDSVDQSKVSDVIYNASKGSKFFNREEAKDQILTQKIAQILEKKRRLEKLDLTRETRQADQLLAQLDAGRDLTQYIVHVDCDAFYAAVELLDRPELEHLPFAVGGGVLTTCNYVARKFGCRSGMAGFVAKKLCPDILLLPLNFEKYTAKAHEVRAVLADYDPRFESASIDEAYLNITEYCKNHNLTPDEAVQQMRDEVHAKAKITVSAGIAPNAKLAKICSNMNKPNGQYRLPNERAAVMAFMRDLPTRKVNGVGRVLERELLEIGVRTCGDIYEQRRLLRQLFGDKTFEFLIMCHLGLGRTNVQPAEDYERKSVGTESTFRDMADPAQLRDKLRWIADELEKDMRRAECKGRTLVLKVKLHTYEVLTRQVVTPKAIHLADDLYNYALPILTKLMQEVPGMKLRLMGLRCTNLVSTKKPDTAAFFGMSRPLRRSESGDSPEPSTTAAKRKASSIMDGEWEEWPEEALYGNDAELEGQIDAQTGGGTLDDEGKENYRHHGKEITPIHKKVASPPVEETWWDCPICMRPQATDERQFNEHIDLCLSRQTIRDAVQRDSASNSPSGTSSNIESLPDSKRQKTGGGPDKKRGRSAAMAADPRQKKLFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZA1</accession>
    <name>A0ABR1VZA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitinase</fullName>
            <ecNumber evidence="2">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009922</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666199.1">
        <property type="nucleotide sequence ID" value="XM_066814237.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047297"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF333">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046971517" description="chitinase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="7">
        <location>
            <begin position="119"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="8">
        <location>
            <begin position="185"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="7">
        <location>
            <begin position="547"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="7">
        <location>
            <begin position="598"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="745"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="903"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1051"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="745"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="767"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="936"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1056"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1087"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="567"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="618"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1244" mass="131438" checksum="27722B0A35EEAB77" modified="2025-10-08" version="1" fragment="single">TQVHFLGLAAFAIQSLLATTEAASSPGLTHQVPEHAPARPVLDTLPLYTTSQIGGRGLTHTPSLLGNLFGKRQREEDGNGGLLCKNAPCVDDSCCGPAGVCGYGPDFCGDGCTSNCDAVAMCGNYSEGGDTKCGMNLCCSWGGWCGTSDVHCIGPNKFTPCQEDFGSCEIIRPTLCGEDSMTTLGRTVGYYLASNTRDRLCNRIEPKHINAQDYTHLFFSFASIDPDTFQIRPWDEADVPLMEAFTALETETWIAVGGYSFSDPGPTQTTWSDMCSTAENRAAFIRSTAEFMDRYGFTGVDLDWEYPVSEERGGSKADTDNFAKLLREMRVAYGTRYGISLTLAPDYWYLRYFDAKAMEPYVDFFGFMAYDLHGFWDSDVEALGSLVRGQADVREIYNGKQAWGNVLLFIAGNTLPLWYAGLDPAKINFGLAWYGRGYTLQDPSCDQLECPFAGPNAPAECTNAEGVMSLTEIKQLIRQRNLTPRLNAESMMKELVWDGQWLGYDDEETHALKRRFANNLCFGGTMAWSVDFNSGAGDSDHAPVSTDGRCGPDHGGVRCEGSAFGDCCSVAGYCGSTEAHCGSGCLSGKCLQGGETTDGTCGAAHHDSFCGLWEQGSCCSSSGYCGNSEAHCGTGCQSGGCLEAPDHGGGSGPIYIAPEVYDDENPTASCFPPCTFIMPPWVLDGPTTISQPPATVSYLDTWDTTTDIGGGTIVTTAMTETTSTIITLPPVTTTEIEVWNVIWVDDEDDDDDDEIIVGLTSKDDDGPNPPPPPPPPPGRPSSVTGRRGPPKPTCKPGQHCGKPCRSNCGGGGGGGGGGCKGVCGCIGPRCPGNNDDNNNNNNCVGSGCPGGGGGNGENGEDECTTRTVTDIWVSCDPETTTSCTIPRTTQICKKYTTRCPKVSAGRREPQSSQEPPPRHGVTTSPWNKGGGGGGGTPPPITTPPPSGPTSLPPLPSSSAQPPYSGSGCQSYAHTTRCNGSGGRSACVTQDLCVPTAPCPSSFTASGTPVCTGEYSICVITTIVTRCARVGDATAAAVNMLGARPTVTPTASVVGLPSSSPTPASSTPDIQAQDDAEPTTEPGIPAVRRADDEESHARGLDLAAMPVNASELQSVSPSALLPRQNGCGGSANGGCDYIRFCAPGGCAKIENVPCLEAHIYAHTGALSGTEVSAWVIEDGDEKCRGSITCDIWDSDCSGTGYFDCGGGNQMGWNWNYIEYYSSKYESWFPLYLDRTGGDEIVFCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W0E3</accession>
    <name>A0ABR1W0E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010553</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666830.1">
        <property type="nucleotide sequence ID" value="XM_066814868.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047928"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8075890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="56331" checksum="379722E97354558A" modified="2025-10-08" version="1" fragment="single">LSAFWTLRVVWRLYFHPLSKYPGPRIAAISDIWYAYHSLRGRWPWAVEDVLKKYGMSAQNFSPGIDELTFWLQGNVVRVAPNELVFVSPQAFADLYGSHHKNLESFPKTQINNHGNDKRGGLIWEWDPARHREVAKQLGPAFKGSALKAKEPTFHRHIDFFVERMKTLGSNPEGVSLPTWTNWLCVDISADMAYNREMNALKNMKTPPYLDILARFNKALVVIQISWRFPLLSPLKYPYLFTTMRPHSNIRDHSREQLERRIRRKGSALHLDFFEQMVPDDHELPKDQDERRHLEQIAGQLLIAGYEPPAVWFYFTTYHLLKHPDCLGTLTREIRGAFGSYVEISPGSAAKLPYLTACLKESLRIMPNVLTGMPVVSPGATVDGNWIPKGFICIRKKPRNFRDPLRYRPERWLPNDHPLHDPQFDGDNCNGFHPFSMGPRMLFIAKMLWVFDLEMVSGQDMDMDRDLRGWGMLVKPEFRIIFVAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8Q2</accession>
    <name>A0ABR1W8Q2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lon protease-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667337.1">
        <property type="nucleotide sequence ID" value="XM_066811995.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045055"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="LON PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718:SF2">
        <property type="entry name" value="LON PROTEASE HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon proteolytic" evidence="2">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="103" mass="11780" checksum="7146353FBAE2858B" modified="2025-10-08" version="1">MTGELTLTGKVLRIGGLREKTVAARRAGCKMIIFPEDNMSDWLELPENIKEGIEGRPASWYKDVFELVFPGRRQRACQQVQDLRVEEGTWFPVGEREEGRISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8X8</accession>
    <name>A0ABR1W8X8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarylacetoacetate hydrolase- variant</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007767</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667424.1">
        <property type="nucleotide sequence ID" value="XM_066812082.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045142"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="113"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="273" mass="28825" checksum="993DE4AA3B851467" modified="2025-10-08" version="1">MSFERLVRFAPKGKEGEVLIGQPVDSNVDVGKAVRNGEEVQVKVFSGDSALNPGSLTDKVETIARILSPLSASEVGSIRCIGLNVICEPCEGGKHAAPRRSNDVHHTLADDCADYESELVIVIGKTCKNVSEADALDYVLGYTAGNDVSSRKSQLAQSQACYSKGFDGSCPIGPVIVSSAVVKDPSTLTIRGLKNGEVTQSSGLNDMIFNCSKLVSFLSQGTTLLPGTVILTGTPAGVGYGKKPPSYLHEGDEFAVEVTPHVGTLYSVFENEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9C7</accession>
    <name>A0ABR1W9C7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667546.1">
        <property type="nucleotide sequence ID" value="XM_066812204.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045264"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="209" mass="23637" checksum="B4EF0BDEE90F8489" modified="2025-10-08" version="1">MSGTSQSSSASDKFGSNSSSSSIFKLLCQYLNYGDDARSRNQVYLTLRSAHIRPFFEEYARDYLMEAEYVEDIGLEALLEWCKRKDAFRTKKYTSSMATTTSRSSSSSKKSSNRHPPAPPSAKKVSWSALDHAARFVVQALQFSWRNPGGYWSLGRCDLNSVSASDSEDGTEFWQAWLVLRYLQSEWEAENLDSSGSSEDSRDMFRCVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9J0</accession>
    <name>A0ABR1W9J0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phospholipid-translocating ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007976</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667633.1">
        <property type="nucleotide sequence ID" value="XM_066812291.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045351"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="295"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="345" mass="36414" checksum="C2820D4F5EB78ADE" modified="2025-10-08" version="1">MSSGTGNGTAPHRPSFKNCVEVSAFCPVQATVLGYYPNLGINAFLCAGFALCVLGLVGTGVWKRTWGYSTALAAGCLLEFVGYIGRVQLSANPWNDKAFQTQICCIILAPTLICISIYLTLKHVTLSISPEISRIRPKLYPLIFVPADVSCLILQAIGGGIAASAGKSNMTLLLQGDRVIIAGIALQVAVLGFLKGGASPEVLAVWNDKKFRMFAYAVAVAYTGIFIRCVYRIVEMAGGWGNPIMQDEPSFIVLEGFMILIPVAILTIFTPGVLFPDMAAREAMRFRSKKAKNQHAAAADAEKADHGVSGNGGGVTTSGDVTPNGHNHNTNADAANKNASAASSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9P7</accession>
    <name>A0ABR1W9P7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008052</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667709.1">
        <property type="nucleotide sequence ID" value="XM_066812367.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045427"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="126"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="405" mass="45936" checksum="17EEDF777425BB8A" modified="2025-10-08" version="1">MAAIDRLPTPLVGIDDESLALILELERQDAERLGRRTKGKQREGSTPSDLEIALQVYLEEVAHASSFVTDYADMGLAEEMLGLNFNGEHDIAYDIGDIPDEETAREQRVPHGQLPVCPGTPHHSSVGLASASLVVTDDKPRTSHERPCEHEYCRNCLRRLFEDAIRDETLFPPRCCKKAIPLDENTKFLPPTVVQAFRKKTIEFSTPNRTYCHPFIPPEKCVTGVARCHDCKAKTCTSCKKASHGGDCPKDKQLQKVIVLAGREGWQRCPECRTMVELDVGCNHMTCRCGAQFCYVCGTSWKQCDCENWDERRLMQRDHQIDARPRPLGHIFVGDEGNHRAAADAGRNDGLERDLQANHECEHPLWRKRRGARVCEGCGHRMPYYILECRRCHLSMCERCRTHPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB22</accession>
    <name>A0ABR1WB22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acetamidase/formamidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668176.1">
        <property type="nucleotide sequence ID" value="XM_066812834.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045894"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.580">
        <property type="entry name" value="Acetamidase/Formamidase-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.20">
        <property type="entry name" value="Acetamidase/Formamidase-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004304">
        <property type="entry name" value="FmdA_AmdA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891:SF1">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03069">
        <property type="entry name" value="FmdA_AmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141130">
        <property type="entry name" value="Acetamidase/Formamidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="22455" checksum="C6127A0B4DAE8BAB" modified="2025-10-08" version="1">MAGPRSFRGSEFSPTSSPALRMWDLRGAAERRYIEFPTTSEHLKGKIRVPFSLFLGTIGIAPAEGATTPCSLYLPVQVPGALLSAGDGHAAQGDGEICGTAVETPMRCRLRVTVEKGANAKSWCANGPAIVTAPRETRPELMALGVDADMREATRKAVRGVLAWLVAEKGMERDEAYMLASVVGSLKLTEVVDMPNYVVGFGIPLGIFMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB38</accession>
    <name>A0ABR1WB38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pyridoxal 5'-phosphate synthase</fullName>
            <ecNumber evidence="4">1.4.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_008534</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668191.1">
        <property type="nucleotide sequence ID" value="XM_066812849.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045909"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004231">
        <property type="entry name" value="PRK05679.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851:SF0">
        <property type="entry name" value="PYRIDOXINE-5'-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PYRIDOXINE-5-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="9">
        <location>
            <begin position="59"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxine 5'-phosphate oxidase dimerisation C-terminal" evidence="10">
        <location>
            <begin position="202"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8080716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="244" mass="27424" checksum="38E195D95E8FD909" modified="2025-10-08" version="1">MALHTAKDTANKLIFAPAGKEVQGQAEQFKKGHLTRADLDATSPIRQFHAWFAAAQKSDQVAHPETSTLSTASLPLGRVSARVVYLKELDAEGFVVYSNFGTSRKAADLATNPWAALTFWWGGLERQVRVEGKASRITPEESQAYFDTRARGSRVGAWSSRQSQVLQPEGEGDDGRKQLEGWVKESETKFEGKEKIPVPEFWGGLRLVPESIEFWQGRESRLHDRFVYTRKEGTDEWSLERLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBA2</accession>
    <name>A0ABR1WBA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668259.1">
        <property type="nucleotide sequence ID" value="XM_066812917.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045977"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="296" mass="32915" checksum="0CF793FFF3DAD8C3" modified="2025-10-08" version="1">MFPTSAIPPIGTKTITPTKPTQWTSSPSPASSATKSTRTSSCTPAFPSESTSTTPARPKTNAPYPAPAAGRRRRRQPANPLGPRARHPPRQQRTHAEARSALYAQNRFDFCAEFNRLAPNEYRHYYLTMASRLVPQGRTLAAFARAVGPHNASLVRHISILFPYLSTPSAPPPSGDATIPEKGSQILDLIGTEFPNLRAVDIFLCQDLRRRHAPKADLALIDAKLRAMPLLKDIAVYTTFCTRRYAQDFSIRPSLREKIVRQGWTVSPFYAPMHGDKDVAINDDTWSRQLWLSLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC01</accession>
    <name>A0ABR1WC01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GPI anchored endo-1-3(4)-beta-glucanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007803</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667460.1">
        <property type="nucleotide sequence ID" value="XM_066812118.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045178"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="148" mass="16148" checksum="CCA6DBACD8A37F29" modified="2025-10-08" version="1">MAYSLATHYAGQALLDGFSFFTGKDPSNGFVNYQSQAAATVQGLISIDEFNRVRLGVDTYNNYTVSDVGRPSVRLTSYQGFTHGLFIADFAHMPASTCGVWPAYMLSSVFLVWAFNNDQNGTKWPLGGELDIIEGANTASRNLFSAHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC51</accession>
    <name>A0ABR1WC51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668552.1">
        <property type="nucleotide sequence ID" value="XM_066813210.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046270"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022085">
        <property type="entry name" value="OpdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053204">
        <property type="entry name" value="Oxopyrrolidines_Biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12311">
        <property type="entry name" value="DUF3632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8081077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="203" mass="23451" checksum="53E79CD778D091AA" modified="2025-10-08" version="1">MHTTFSRYCYSSLTVAQLVGLLDSVHRLPDLVIRDEAAVKWSELPFLVEGWDQIYNRPEDQHSEEIVCVIAFIAKLLSAQLIPRDEFLRWVEMDMHTALERGPEDPSTLKKDDLVLLNVNVPIAAQWMKYAGLVIWNCEADLGLPKRQDSLWQGSAGFSYSRWKFWKERATWVTQSKLVSSRTRDFAKDMVVEMTSIEKQDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC93</accession>
    <name>A0ABR1WC93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_008940</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668597.1">
        <property type="nucleotide sequence ID" value="XM_066813255.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046315"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04041">
        <property type="entry name" value="C2A_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21676">
        <property type="entry name" value="SMP_Mug190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057349">
        <property type="entry name" value="C2_Mug190_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037767">
        <property type="entry name" value="C2A_Mug190-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348:SF2">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25331">
        <property type="entry name" value="C2_Mug190_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="236"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="448"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="661"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="990"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1024"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1046"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1070"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1087"/>
            <end position="1100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8081122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1158" mass="128395" checksum="DF2C1620058DA9C7" modified="2025-10-08" version="1">MADIFRSSKPAYTARRPVPTINSYVREQQERSAQALSPEDDDEYLSDEETQLDDDDEPGPNETTTKDGAAALGLRPGRGPRLLITLGAKSGRLTGVAGKSKSDDDLERETEDIDAYHAQLDTRFPPPDYEAIKRRLIGIYSKSIVIGLTSAVVVAYAVSVAEGLLGSRGGFLPFASEAAIGSFGFLGIAYAIYAARQWMANRVDDIWEEELWRAERNSDGLEDEATIGARSIADIDPASTRWLNDMLSSLWPLVNPDLFFGVADTLEDVMQASIPSIVRMVSIDDIGQGGEPVNILGIKWLPTGPQDWDEDAMKGLQGEDGDFLNLEVAFAYRPQSVVSDEAKLQGRSQHAHLVMGFYLPGRIKLPIYAHLKALVGKARLRLTLIPDPPFFSSVTMTLLGQPKVEIACMPLVQKGLNIMDLPLISSFVQTSVDAAVAEYVAPKSITIPLKDILAGRDYKLDPRARGIIVIHVKRAYSFKQGDQAIPLLRPEGSSDPYVTCGWAKYVKPLWSTRVLIAEMQPWWDETAFLPVTDDELNINERLRVQLWDSDRFTADDDLGRVEMDLRELMRDPATVNRMQDRVDGFKALKASERMPGKLEWSVGYYPKLPIQPAQLERQTELPSVRTPEALAARADENCRRKLRGGPKIDDVEGTRQAEHKEMEDRMVASAPPLADFPSGVLAVQIHEATGLEIRAHHNADRRNRGTEVDDEVEEGEELPSAYCNIILNHEKIYRTRVKPKNARPFFNASTERFVRDWRAAEIFISVRDSRAHEDDSLMGLVYLPLRDVFRERAQVDRVYPLFGGMGYGRLRVSMVFRSVGVHLPRPMLGWEYGTLAVAPRVGAQDVSAELQGLTMKLDTSLSSGHMYYHKPPSSQSAANGPIGDAEHHQPFWATAQGKMLHLGVRKRYSSPLVIQFRKERRLRVVDSKTAVAYAVLWLSELPDDEETAVTLDVWKGDLKRASTCTLPKEEAGDEKVGQISLKVRFRRGVGRGDGGVPAAEGASGGRGVVRSAAKAQTEGVAANGGVPPKSSSGKSANTEGTAVESTSEDSDDDGGDDEDGFADAKSNIVEDADSAGDIGSDEDEDDKYLQDESNRGMRDALRDYRSHAKQTHRRHRGMMQFKSARTLWWMKHKVGYLQDRVSGKLEHGDRKTVVESEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL00</accession>
    <name>A0ABR1WL00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="2">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005466</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668704.1">
        <property type="nucleotide sequence ID" value="XM_066809781.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042841"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056584">
        <property type="entry name" value="EF-hand_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF82">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23617">
        <property type="entry name" value="EF-hand_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="5">
        <location>
            <begin position="431"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="563"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="387"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="407"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="729" mass="79784" checksum="B771E4C146B25E56" modified="2025-10-08" version="1">MGDPGAVQMQDSVHQAGGGQPSGDPRHIQKLNPSVLPHLEQLFNRHAGFDRKWNKDQVIAFLHHVQADKVSDPSDDLAAQDSLDFGTFLHYMSSSAADALAPVHNEDFTWPLNSYFISSSHNTYLTGNQLSSDSSTDAYKNVLLRGCRCIEIDVWDGDSSDSESSASDSDEEEYAEKKAIRKGSRKERLAKHIPSSITSRLENTSLGKRLEKYTSHESDKGAAKDATKDEPTGAARDATNIASHDASQGSVASGTSDGTAAKNAIPAENTLPVPEANVLPALQRTASPQAIAVEPRVLHGYTLTKEVSFRDVCEAIRDDAFTVTDLPLIVSLEVHCSDVQQEAMVKIMNETWAEFLLPPPDADCKVLPAPGDLKRKILVKVKYAPPSTGSISTDRLASSSTTSTTASDKDGLPPARADEKPKKPSKIIQALSQLGVYTRGVTFKSLAQPEAQMPTHMFSLSERGVLEVHEKQAPDLFRHNERFMMRTYPSGMRIGSSNIDPPVFWRKGIQIVALNWQKWDEGMMLNEGMFAGTGGYVLKPEGYRGQKPVVAAADNADAPAVTTAGEIITAPLGTGDARILHQALDLKITVLAAQDLPLPKEGDNPSGFNPYLKVELHTEPHYSELLKQREHSGKAKEGEYKAKTKTKKGIHPDFKADVLEFKQVMGVNPELAFVRFVVKDDEIGHDDLAAWACIRLDRLKRGYRFIKLMDKNGMASKGAILVKIEMKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL37</accession>
    <name>A0ABR1WL37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_005520</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668758.1">
        <property type="nucleotide sequence ID" value="XM_066809835.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042895"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045908928" description="CFEM domain-containing protein" evidence="11">
        <location>
            <begin position="22"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="12">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="157"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8084249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="225" mass="22171" checksum="070AFD81F7C2D37C" modified="2025-10-08" version="1">MRLRRHLVLAAGMMATSITSSNWAEAAGIEMSSCTRSCYAATVYFLGCNPSDVGCACKQQPNLIYYAEPCLAQECRDDDLILALTSITDLCGDAGGGGGGSGSGSGSGTSGKVLPPATQTPTTGSVFSYKVTAPSTPTTIPGTTVGTRTIAPVTIKAQQAPVTVTPPGTGSSSGGSTVGGGSGSNSGGGNGGQEEGKSNGGSVAWHVEIGAVMLGCVGLGAVLVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLP6</accession>
    <name>A0ABR1WLP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005706</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668944.1">
        <property type="nucleotide sequence ID" value="XM_066810021.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043081"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF38">
        <property type="entry name" value="POLYAMINE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="73"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="509" mass="55391" checksum="BDA7AE50916A1665" modified="2025-10-08" version="1">MADGPTPPPANQDTPDEEKQSNANSANEEGNGGDNGAGPLNGSTTNDSQTPAWEWRDDPANPYNWPKWKKNVQLAMIAITAFSGSLATSIVSPAHGEFMAQFGVSSTVAFLPLSLYVLSLGLGPVLGGPLSEVAGRRIVYLIAPTLGGIFSLACGFTRSFVGLCIMRFLAGFFYAPSLAVGSGVLNEIYYPAERGLPLALFILSPFLGPGLGPVVGVFLVDRKGWPWTQFTVVFLSVFTLIWVLLTPETYHPLLIRRRMSQLHLTPPKQPPFASLVSQFLTIGLVRPLHMILTEPIVGILGLYIACEFGTLYLFFGAFFLVFQGPTYGFTLVQSGLVFLAVALGCVLGTGLVYLCDRFLYRPKVKHFPPNQIPPEHRLYSAMFGTLLLPTALLWFGWSARPGVSPAVPIVAIALFACGNVSLFISSMQYIGDVYHRTNVASAASANALMRYIFGTVFPLFGLQMYRRLGTGWATSVLALIALILLPGPWLLFKYGKKFRAMSKYETASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLR0</accession>
    <name>A0ABR1WLR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Polyketide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_005719</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668957.1">
        <property type="nucleotide sequence ID" value="XM_066810034.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043094"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05274">
        <property type="entry name" value="KR_FAS_SDR_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020802">
        <property type="entry name" value="TesA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF21">
        <property type="entry name" value="NON-REDUCING POLYKETIDE SYNTHASE AUSA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00824">
        <property type="entry name" value="PKS_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="9">
        <location>
            <begin position="455"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="10">
        <location>
            <begin position="1355"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="1706"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="1803"/>
            <end position="1880"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1355"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1507"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1881"/>
            <end position="1908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1882"/>
            <end position="1908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8084448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2188" mass="233899" checksum="05219B89FD5F8F5B" modified="2025-10-08" version="1">MQDFGLVSRVSWTPASPSEDQANFDKVVFLVPGDDEAYNSEAVSAYQAQLADENYATAVVSHITEHDALLASPGSIIVHIPNTPSTKDGIYEAVHKSSRVLKMEIPDIFGGLFEVDQPSFPTSAIKSAHGHDIVRVCDGTAHSASLEPLSDQSNNESIQSRLQLGPENTYLVTGGTRGMGLEIATWLTERGARNLILLSRQGMPVVEKGSKPDAGAEKFLSQKSALEAKGVTVHVLAIDMGKPEAGPQLRDAIARLGLPPVKGVVHAAGLAAYHTLDRCTPAGMAEVLAPKVQGGLTLDALFLPRTLDFFALMSSMGQLVGFEGQLSYAPANAFLDGLAARRRRQGDNCTAILWSTWRGVGMAAQSKSATRMIDRGMRDRGFAAISAEEAFAAWDRIAGLGTDHAVVVRALEATTDGSRPHPMLKHIMPSELALRGERGTQDSAQWKQTAIEYPDDAVAVVGMACQTAAGETAEDLWQVLLEGKSMVRKLPLDRFPEMAGKPPMSANLMSNIENFDHQFFKKTRREAAALDPHQRLLLQTTYHALESAGWVGGDKQEPETHKTPGPTTSTGCFIGMNAPDWPLNLASHPASPYTGTGMLRSFAAGRLSHHFGWTGPSQTVDTACSSAMVAVHQACRALRLGECTRAVAGGANLLTNTALSEALRAGGFLSATDGPCKPFDARGDGYCRGEAVGVVVLKPLSAARRDGDDVLGVLLATGNNQNVNSTSITNPVLESQAALYRDVLGRAGVRPQDISYVEAHGTGTKAGDPVEMGGIRQVLGGKDRASTLHIGAVKANVGHAEAAAGVVSLIKVLLMMRYGKITPQAQFQSLNPNIQPLENDGLAIATSLKGWNDGMRLALVNSFGASGNNAAAIIAPPPLKETEPAVSSANSASTSASFPIIITASSTTSLSSYCEKLKSRIEDPSRQHQQLFCTTAKTLGELQAQLSSPEKLTSAAQRPRPVVLLFSGQNGNTVPPARPLYDSSALFQKHLHQCDEALQSLGFPSLFPAVLEGFQGDSDIVLRHAAMFAIQYSSGMSWLDSGLQPQAVCGHSFGEWAAATVSGVMTLDAGMRLVTGEWIILIAKAKKAIRRASIIQKLWGDDTGSMIAIEAELVKKDITPELHLEPFLKQHSKTKISVACYNGPNHYVAAGPTPDIELLEAYMKDRKSSGEAMRFKVLKGMHAYHCAMADPIVEESGKLSSTIPFQEPTFPFESCNPDTWTGPASNVIASNTRGPVYFTQTIARIVDRLGPSTFLEAGFGGPIVAMARNALSQSQSQHTFVAIDGKKPAQSLADATATLWKNGQPNVQFWPFHKSQRGSYASVVLPPYQFEKNRHWLNYTADKGEALASLGQCPHCLKRASDVPYIVQDKSSSRTDAETSPALPGAHRGHVVVGTPICPASMYMELATLAVTSLKPTAMSSEITVNSLAIKAPLSLDTQRAISLAVTKRSEVAWEFEVSSTKGSERLTSHATGTVNLGGHSSSILNDDQSDDWDKWARIGRLLEKDTDTDALRGAMVYKVFSAMAQYSPVYKGLKHLVGKGAEAAGDISMPALDLDPAARAPNDSIADTVVVDNFLQVPGAFVHSLRRGTAGEEDEQDGGMVYTKAIAESSNKVTLNMFALDKVTQKTVWSAKGLQFSKVPRSSLAKVLAGANPDKELGRLQVVVPPTTAPSRLPIQEKTESRLQVRSVPSSTPVQAVTASESKPDLVISGVQEILAKSLDVPMEEITKQATLEDLGADSLVSPEILSSISSKFGIDITSDEFASATNVALLCALVSSTIGGPGNDSEEGQEPEMATPAVHIDTATVWQDAVFKSLGDSLDVPIEEIQMDSKLEDLGVDSLISGEIITRLNEALNVDITSSELASATDVASLCQLIAESLDGGSSATPQSQSTNEKPSATKRTSPSKATSMLLHRGSASAAKTRNLFLVPDGFGSGAVFGPLAPLLARVTDVSVYALNSPYLTRDNQPADLDLDLLPTLEQLAAAYVAELRRRQPEGPYLLGGYSVGGLVAYEMARQLLEDGCAVEKVFLIDTVCPTLATSLPDTLVDFFESIGSHLGVANEDEVRAKNGGRLLTSRHFTLARRQLSRYKVKSGLPGGQKKRPQFVLFSAREGLDKQSAIARPTLSVEGERKMAEWFLDDRSDSSGALGWEEFLGSPVRVERADGNHFSMMTPQMVSSWGSKLAELLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLR8</accession>
    <name>A0ABR1WLR8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glucanase</fullName>
            <ecNumber evidence="11">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_005703</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668941.1">
        <property type="nucleotide sequence ID" value="XM_066810018.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043078"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF1">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE CELB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 11" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045751667" description="Glucanase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="14">
        <location>
            <begin position="413"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="378"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="382"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8084432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="50365" checksum="B602A5A1931CBCED" modified="2025-10-08" version="1">MASRTAIAFGLVAALAGLQANAQNPDDTAEASPKLTTYKCTKAGGCVSQDTSVVIDWNYHWFHTSDWLSCTTSNGIDSTLCPDQATCAKNCQVQGDSNYTANGVATTGDTMTMNQFVYGANGLQGASPRVYLLGADGNYVLTKLLGQELTFTMDATGGRNPYNTGGAKYGSGYCDAQCPVQTWRNGTLNTSGAGYCCNEMDILEGNSRANAFTPHPCTDTDCDKGGCGFNPYSQGHKDYWGPGGTVDTSKPFTVITQFITNDGTTSGTLSQITRKYIQNGKMVASAVSGGDTITADGCVAASPGAAQFGGLPGMGKALGRGMVLTFAIWNDASQFMNWLDSGANGPCSATEGDPALIQKNHPDTHVVFSNIRWGDIGSTFESGAPQPQPGTTTTAKPTLTTTTKASTTTAAGPVQTQYGQCGGTGYTGPKTCASPYTCKVSNEWYSQCFCTYCVWLLGLPGKSKSLSPKLFPLQQAGSLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLW1</accession>
    <name>A0ABR1WLW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669005.1">
        <property type="nucleotide sequence ID" value="XM_066810082.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043142"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039323">
        <property type="entry name" value="ANKRD_45/46/60"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677:SF4">
        <property type="entry name" value="USHER SYNDROME TYPE-1G PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="79"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="145"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="19858" checksum="573BEE8093E6F3BD" modified="2025-10-08" version="1">MLPSLGSAGVEGSQPPTPSGMLSPPLSTPHGRSSSVTSTLHTCPIAKPSLNLAPRIIPPCPTALMMSTTSAVPREPFRKGRTALHISAERGNIAMVTFLVENDVDLDAPDGQGRTALHLAVESGHFPVVAKLLEMGADTDLVDYNGLSPIHTAAESDREEILSLLIREGADIHARVAATDNNDRKEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMK1</accession>
    <name>A0ABR1WMK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial inner membrane protease subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006019</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669257.1">
        <property type="nucleotide sequence ID" value="XM_066810334.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043394"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037730">
        <property type="entry name" value="IMP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041:SF2">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="35953" checksum="6EB2548B592EFA40" modified="2025-10-08" version="1">MSPTYNPENSLTGRFYYIGKSVAPSELRRGMFISFRYGGNPSPHSVVPLPDEYSCFCLRSTILNNFPLGKRLTGLEGDIVRTRRDCTECRHVRVPPGTTWAEGDAGAYLSEDSNDFGPIPLRNVVGVVTFILYPFKYWGRVRWWEYQDIIMKARLVTDPKEVKALEEKGAKLDFVMSRASEQDFIQRRLKEQEESGEIDYQAEAVRGMAAQFLQEASVRCLQVRAANRAKKANAKVGDTAASKPQKSRAAARKGQAAGTEDTVLGRWMAHGARSQLVEKDVVLLTLPSAISEEDQRVLRKKAELTKEKTGWTYQFRFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMN3</accession>
    <name>A0ABR1WMN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669241.1">
        <property type="nucleotide sequence ID" value="XM_066810318.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043378"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="89" mass="10527" checksum="A5948626C5DA8E5A" modified="2025-10-08" version="1">MEPWCIEHILKHTTLSQIRSIWSYLFNGWKAMYHRDDLSQSYSLAKPDYTDKLRQALARGLFMNIAYHRSQDAYVTIHGNFEGIPAHDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP46</accession>
    <name>A0ABR1WP46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PEBP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669800.1">
        <property type="nucleotide sequence ID" value="XM_066810877.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043937"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF141">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045207463" description="PEBP-like protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="20689" checksum="EF22193A06EFAB9B" modified="2025-10-08" version="1">MKFSGIYALVVLAGLSTAQTPDGFEPQVTPHLDVIFGSKEVTPGLSLTKSDTARAPTIGLKAQPNGTYVWMMIDLDASTNPFNPKQGKPATYLHTVLRDFKASGQKTDSGVYTLTTRATGPVAWFAPAPPAENPPHPHRYTHLLWEQPENWVIPQAAQTQLQTGKTAFNVPAFQKAAGLSAPIAGNYFNQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPI2</accession>
    <name>A0ABR1WPI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669943.1">
        <property type="nucleotide sequence ID" value="XM_066811020.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044080"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="58"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="627" mass="70745" checksum="A85E3C4496F7F75A" modified="2025-10-08" version="1">MPVPLEIPGDNLYAPLNPATPEDPATSDVRFLELLPGDFDEAMHCSLRTCSLKNHPKYEALSYVWGDARVTKPVYVNGHLVQVTSNLTTALRYLRHHQRPRTLWVDAICINQADILEKGQQVPLMGLIYSQCSQTVAWLGLPTPEMMPVISLMSPYLSVRYWREKALKLYRDVMAYTSSNNTMRRNIYYRKLGLATILVSKFPYWTRIWTYQEFWLPKKTVFVCGTLVFEPLLRSKRWDAQTIIRNAYFTPEIPQNVDASLLAEWNQLEMVMEGHMLAGLQYGFMLELYGDGKNPSPEKAFTLTLLHTTGRQCTNVRDRIYGLYAFTPRLRKIYPVEYNKPACVLMYQTTAASIQLSGMIMYTGFALHSSEPIGVSIPSWSLDFNKPFDFPTKVPMLIVPDAPEPGHYSSKPRAPTVTRVTLTLPAHVMGTITSPLRLSHDHTALAGELLRILRKIDEYHMRIRSALASFIDMEQITRNEVLLQNMLQYHSQPPSQHGEIGHGWKISPEFFEKSVLQSLAGKTVALFDAVGLSDGEQGAASIAGIVSGRAVEGDVLILPTCDGPVIGLRREVQPWVDVSPAEDTYFTMVGVVWVEGMSGTRAADMDENGKRLVDATRKTGYEDFVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQG3</accession>
    <name>A0ABR1WQG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycosyltransferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007058</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670296.1">
        <property type="nucleotide sequence ID" value="XM_066811373.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044433"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="502" mass="56921" checksum="975A0B6A85D3C90A" modified="2025-10-08" version="1">MTLLRTGETTRILPNQPHTLHSLYDLYDKHIEAQNQKKYRPFPILPPETRRYHPSDVSLVVPTVDADPSTFAACLRTWARCQPKEIIVVTTAGEQEARVREMLMAVQTADRIDDKTKPGSLVVTAKVELLTVDRPNKRHQLVRGIRAAKGEILALVDDDARWESEETLASLLAPFEEEDVGVVGGPIDSYLPPERRDPSVVTPWEVAALRLRANRHARMRAAYAADGGINFCVSGATMLARAAILRDDPLFRFEFVNEHWAGRRQNSGDDTFITRWCLFHHLLDHKARRREMVAQLKKDAAACHGAGYQALAARHPDDGAGHRAHVPQAGLRVRGADEEVVTEWYAISYLPYPVKSGSLTRRDAGLRLRLTCLLFEPGIVKMYQTTPYMARKMVECMLLPFLHWLYIGCWFICLMQAPLLGLGILLYELYNWANSMFGFVGRFPYAAPYWWAAALIEKAQLLSDFYCWATLGTENWETRNTDGDQESNPLLLVDEIVHGKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRF3</accession>
    <name>A0ABR1WRF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006958</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670196.1">
        <property type="nucleotide sequence ID" value="XM_066811273.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044333"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="190"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="254"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="191"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="303" mass="30951" checksum="48AED5BCB1EBB860" modified="2025-10-08" version="1">MATTATRTVLGPLTTFFTPDPTCVTPMAGSCDQTLCHAWAGQTCHLSSDSFTVFDQTACWPPVTKGVDMPAIEALNGWGLYSPGLSCPDGHVRACTKTGGDVEGFAFQFPPTAGETAVGCCPSSYACSRAGGPRSAQTCMRIMTKASYPVVSCGGTISPGTTAASRTASGATFHVLVAPMIQMNWQASDLPGAATTTPSQSATTGTGPTTGTTEAPAPSGLSTGAEVGIGVGAAVAGLLLLGGAVYLILSRRRRSRGQNETTGVAGDQPKTGDGGGQQQQQQQQPNRNIVYEMGQTPRAHELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRI1</accession>
    <name>A0ABR1WRI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_007048</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670286.1">
        <property type="nucleotide sequence ID" value="XM_066811363.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044423"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="158"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="493"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="326"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="386"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="587"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="398"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="414"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="617"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="631"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="739"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="759"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8085777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="798" mass="88923" checksum="A1D00FDA866CF99A" modified="2025-10-08" version="1">MLKNFRAGDRLRYPITISKFLKNKGDEVQRGEALLQYTFKFERTIGDPALNEERTVEETGYADWDCPTEGTINKWLVKVGDVLTKSQLFVAIDEPCPHDMQYAGLCTKCGKDMKEITWATESMDTDRATIAMVHDNVALTVSAQEAMRAEIDLQRRLLQQRKLSLVVDLDQTIIHACIDPTVGEWQRDPTNPNHGAVKDLRPGLVGFLERMSEYFEMHVYTMGTRAYAEQIANIVDPDKKLFGHRIISRDENGSVTAKSLQRLFPVNTNMVIVIDDRADVWPRNRQNLIKVTPYDFFKGIGDINSAYLPAREDVLGTAAAAAAPPAATSAPLPIRNGDASKSPNAPGHANKIPEHEKAVAPNPNGVDDALLQLQAQEQERALEKQLKERPLLHMQEELDKEDTDPAESEASEEGTTTPPDSPEQQQNGHSPTPHHRHNLLRDDDNELACVEKHLTATHKQFYEKYDARRASRHRLQEITSELIPNVGVVLDYLKGQVLKNCTIVLTGIVPQGVDVMASEIGLQIMSFGADLKRKPTSRTTHLVVSSARPRTDKVRKAARIPSIKIVNQDWLAACLAEWRRVDETPYLMDINPGDRANRHVPAADDDMEDDDEDKSQPKITIVNSGQQNMFEEPDESAGDVSDDEDDDDDEEDPPVQELKKMDWDDMDDELAEFMGSDVESDSEAESMYQGSGKRKHDDLASEDGDSAEEGTGSTLSKKQKLAKARTTGLRNVENVGENGADDDAAAEEEGGEEGNTQDGGDEEDDFDELEAELEAEFEKEDVEEQEGAVATEDQHMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRM2</accession>
    <name>A0ABR1WRM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LCCL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669367.1">
        <property type="nucleotide sequence ID" value="XM_066810444.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043504"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051957">
        <property type="entry name" value="CRISP-LCCL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004043">
        <property type="entry name" value="LCCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331:SF1">
        <property type="entry name" value="CYSTEINE RICH SECRETORY PROTEIN LCCL DOMAIN CONTAINING 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03815">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="2">
        <location>
            <begin position="119"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="383" mass="40783" checksum="53471AAF766FCC00" modified="2025-10-08" version="1">MSSSARVQTSAGSQSLLGLVGSKEPRRLSNGWTSKRVTAASQQLPTARWFRHKFPRSGQRMAVYLAVSLVSALAVLMLSRTGSGVPPMEVVDGVYQPVEQLSCTDSFWLPDNGCGIEGEKCQPFSENVLAFRCPANCVAAAKKKTTKSAASSSKERPHYVGPEAITDGRPLVVGAGPYFRADSHICAAAVYSELLKDAEGGCGIATTSGMTSMFPAGSPEYGVTPVPLRTYFPMAYRFKYDSGIACGRPQDESDISSGRARVVAPLLAAASYTALVLFFANSAATRLLSAVAAGFLATRIALTGPDVSALPAHFRTAAKSGHFLPAMGAFLVALAFAAIVLRLSTWRSPQRLTTTYDKTALWLGAFWLGLLSLYLFPGCRPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRW0</accession>
    <name>A0ABR1WRW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670089.1">
        <property type="nucleotide sequence ID" value="XM_066811166.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044226"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="51089" checksum="A78D501BBB61E0B7" modified="2025-10-08" version="1">MSPHAPSGPRRRLGRCLSHALHIRVPVSFLNPTAGFVAVSRSGGRAATRSPYRHSVESGRRNSLSPTPSNTNGRTTTTDGSATAAAAEKPSPGTAYHVWQTRNNRKGRHAVAVRVPSHLAGTGLELPKATNTPRQILSGIRRMAVRYPVWDVSYDVAIMFTIGKLSLPSPFPFLLLKKGVRGRNIISDEMSFLGSVIWVINAFFVWLPLQTPSTAFANETSLGGGITAFIGATVFELGSVLLMLEAVNENRTDCFGWALEREAKAATRSAEGGAGDRLRLPTSGLFSPLPKSRKMMLTAVAKRNSKERGRGNGGPWNELATHYFREIGFLACLAQFVGATVFWISGFTGLPPIFDALSTPAANGIFWLPQVVGGTGFIVSGCLFMLEVQPSWYRPAPKVLGWHVGLWNLVGALGFTVCGALGFAIGDEGVEYASTLATFVGSWAFLVGSVIQWYESLDKYPLVLSKSISTIPHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS94</accession>
    <name>A0ABR1WS94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670177.1">
        <property type="nucleotide sequence ID" value="XM_066811254.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044314"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="30001" checksum="6B90FB5818A3DC86" modified="2025-10-08" version="1">MEQQLRRDGPVLLLAPYTPGAATTDVAVTGYLGGWGFYSPGLVCPSGSTSACTKTADNPTDGGFTFQFPLTAGETAVGCCPASYSCALDASGRNTCLRTVRSTFYGVVSCGGTAPPGTVAGTWYATSTTYHNIYAPLIQINWRAEDRPATSTNTAVATATTPGSTNPAAPTTSSPSDDPAHSGLSSGAYAGIGIGAALGGLMLLGGAVGGCMLLRRRRRKTQDGSGGGSEPKGPTTNQDAWQQQQQEQRPASNIYEVSESGHTRETHELFTPTPDGGSTLVERQQRMEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWU2</accession>
    <name>A0ABR1WWU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670533.1">
        <property type="nucleotide sequence ID" value="XM_066806915.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039975"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="32297" checksum="95D2E2DD2F66BD41" modified="2025-10-08" version="1">MIGHLIEEGTDVSPLAVYSSHSYGQGKTLLQIASRHHNLDAAQLFLERPEGPVMARQRDSQGQQALPWAAIGLFPGHRQWLEPMSDVEVTHRAIETIKALLPYNGVNERGTRGMTALALAARFCKPPMSAYDSSCFDPAVQFFLDHGADPCDAGDDYGDTPLHAALCSVDRITTVRLLLSRGARADVHNRKGDTSVHVTAKMYKYLQLRRKARNVENLEDREERQRVAMQLLLDSLGSADIMDQQIEELTTAEIPQNLEEDKKWLRRIQSRVYHIRLSSPSDLLGSGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWV2</accession>
    <name>A0ABR1WWV2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002612</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670545.1">
        <property type="nucleotide sequence ID" value="XM_066806927.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039987"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF37">
        <property type="entry name" value="CLAVALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="298" mass="31015" checksum="99DB2FAA64250F37" modified="2025-10-08" version="1">MGLTAPFEFPPATGANFTQTIHQKVPPALKPSVQTLPTPFVVAITGASGGLGRAAAEVFAQAGATGLVLSRAHARGPGGDEADLRGSIIVTLVVGSVGNEADAQKLAAAVRDEHDGRLDMLINNAGVVSTHESAWGPFDKIRPDQFEVPMQTNYVGRFLTMQALLPALMASPGGGTVVNVTSICSHLTSPGHGAPGYNISALASNRLTEMAAEVYAGDGGAGPVFYSVHPGAVATHIPVGASQEMFEVLCTEEADLCGAVCLWLGRNRPSWLNGRYISATWDMEELQARKDEIVGAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWW8</accession>
    <name>A0ABR1WWW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002580</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670513.1">
        <property type="nucleotide sequence ID" value="XM_066806895.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039955"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF5">
        <property type="entry name" value="CBM1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="8">
        <location>
            <begin position="59"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8087619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="345" mass="36762" checksum="9B8F889F0DACC4EA" modified="2025-10-08" version="1">MDQCCADQPSTAPTTTAGSGSPTSAPGGKVKYAGVNIAGFDFGMVTSGTQDLNAIADQSSSGVQQMRHFVNDDKFNIFRLPVGWQYLTNGSPTGNLNANNLARYDAFVQGCLSLGTYCIIDIHNYARYNGAVIGQGGPADDQFVALWTALANKYKSQSKIVFGVMNEPHDLTIGTWAQTVQKVVTAIRNTGATSQMILLPGTDYTSAANFISNGSGPELLKVKNPDGGVSGLIFDVHKYSDSDNSGTHVECTTNNIDNAFAPLATWLRSNRRQAFLSETGGGNVASCGTVICQQLDYINANNDVYLGWTSWAAGGFGSSYELVETPNGNSDTYIVSQCFAAKWKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX39</accession>
    <name>A0ABR1WX39_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670621.1">
        <property type="nucleotide sequence ID" value="XM_066807003.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040063"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="382" mass="42987" checksum="55A61E754643E602" modified="2025-10-08" version="1">MYPYLTEGQPLSDFARLVSVIESTRIEWRSRTPLVALQLLRKFRSRKASDPKDKVFALLGLVQYWGRSQPVSADYSHSIETTFLGTMMMLISSTESLSVLAGSTGRACLAKRRAPSWVIDWSFPEEENEYNRLKSLVLYSAGANLQGSVRLHGGGILESPAYWVGKVEVVGDELVVQAATKMRKTVSSWESLLAYAEDPYIPGESLKGAAESGWEQWRSADKKHNRKTSLVGRHWLEVPNLTDNEKRRNAFNYALSCASGRRRFFVTDEGHIGIGPEDVTEGDDIFILCGSQVPFVLRQASRKPRACQNAIPETLFRKSRQRQYIPAGRDANEGMLQTLKGEASICNRVHWPCYTVVGDAYVHGVMQEEQNIERTQTTVYIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX56</accession>
    <name>A0ABR1WX56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670636.1">
        <property type="nucleotide sequence ID" value="XM_066807018.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040078"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="270" mass="30440" checksum="F13ED9234D8F02E4" modified="2025-10-08" version="1">MTAPVKSCVQDPIPPLASYEDLKKEEWYINVNREIRRLQWSLDGPLDKAVQVMRHAAYDPDDPPLNPSTAPEQTTTRLSLFEPKVSSVTIDVHCLAEWADVWSDMHLECDCLSFEDDPSDVDEEDDHSETRGGRGGYVTIRDFVTAAHLWLLGLRALILRAPRGDQLFNLDLLYEDPEPEPALQADTKLMVLVDGSLHSVGIDVLPESEWLIDSRTNPFPEQPCPPLPRRYTPPPPPDMTPVGGIDPSVERWNKERPPPRLLDAQVWPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXD6</accession>
    <name>A0ABR1WXD6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002785</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670718.1">
        <property type="nucleotide sequence ID" value="XM_066807100.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040160"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF804">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="226"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="400" mass="44818" checksum="380C012627A3BBD9" modified="2025-10-08" version="1">MADVLAPISSATQPSAVPGQDKKYVYFHSGSEATYREVSDAPSSSFTSIPTVDLADLDSGSLEARKRIAREISDACRQCGFFYIKNHGVPEDVIRQTFALLRRFFALDHDVKMEAHVQKNPAIRGYEPMLETNLDPRTKGDIKEAFTMGDCYLEPEQDYPGKTGAPGPPPHVTQPQNIWPPAAPWWREGLYAYYAHVLPLSLKLVRIFALGFGLDETAFDPMFRFPITGMRPLHYPPTPGASSSSSSMEEEGNVGLGAHADFSWLTLVLQDDVPALEVLNQAGHWVDAPPAPGTFVCNVGQYLERQSNGRYPATVHRVRNKTGKERYSLPFFLTPGPEVDLEVLPSCYDDHDPENPKRYDTINVGDLYIRRVLPARKKHPTSIKYRDVLQEQWSYSMLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXF8</accession>
    <name>A0ABR1WXF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002807</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670740.1">
        <property type="nucleotide sequence ID" value="XM_066807122.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040182"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF213">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046382228" evidence="2">
        <location>
            <begin position="17"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="3">
        <location>
            <begin position="491"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="641" mass="68747" checksum="B9815208E8567A1B" modified="2025-10-08" version="1">MKPVVSAALLAGTASATSTANSTYEYVVVGSGPGGAPLAARLALAGHSVLVIDAGEDHGTDRQLEVPALHPYASEYNPSRWDYFVNHYANETQAIRDTKMTYVTPKGEYYVGTNPPEGSVRKGVLYPRAGTLGGCSQHNALVTVKPTRNDWNHIAEITGDDSWNADKMQGYFEKMESCNYLPNSIAGHGFGGWLQTRLTPVGLIAEDLKVASLVVAAATAMGKGLLGKLVHTVTGLLEILALDINNPGKNRDSLEQIYQIPLAMDENYSRSSPRTLLLEVARATNDDGSKKYKLDIALNTLVTKVKFDTSATTPKATGVDYLVGKSLYRADPRASTEDGGIPGSVYASRELLKLSGVGPKEELETHGIEVVKNLPGVGGNMQDRYEVGVVGKAPTPFALLEKCKFLNGTDPCYDQWTHGVGGTLKGGYTTNGIAFGFLHHSSQADKHGDQDLFLGGVPAFFNGYFPGYSVHATSDLSIWTWLTLKAHSRNNAGTVNITSANPRDTPQITFHSLGEGVGGEQDLQAVLEGMKYGIEAFEGLVPLDGAFDRVWPPPEVKSDEDLKQFARDEHWGHHASCTAPIGADDDAMAVLDGKFQVRGVEGLRVVDASIFPKIPGMYIVAAIYMASEKAADVIIEAAKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXR5</accession>
    <name>A0ABR1WXR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CorA soluble</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002903</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670836.1">
        <property type="nucleotide sequence ID" value="XM_066807218.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040278"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12829">
        <property type="entry name" value="Alr1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044089">
        <property type="entry name" value="Alr1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535">
        <property type="entry name" value="MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535:SF51">
        <property type="entry name" value="MANGANESE RESISTANCE PROTEIN MNR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="829"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="405"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="654"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="421"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="449"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="657"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8087942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="856" mass="96646" checksum="61F2A127870A1A30" modified="2025-10-08" version="1">MATSGNPFSPLDRARPTLAGPSQTTPAESSNVSPGSQIPKKKKHRGGRKHRRPRRKSFAAPADEDGGPSSPRRGGDEPTSSRPNNFYMRGRNLSNTSIESEALLDHREHPWGSRPRRPSTIMAASQADDDNNDEEQDELARMSESAPLLPGPTRTESSSRIYGSSDGMGSWGGRQHRDSMHRGSSKSSWRGQSGLLGPPTPGTERYNVNYPPSMPGSPRLGGLDRMDVNFGDELMLDQLASASKDDVNSLGDEDTGDHHMHGSPSFQRRHTIALEAQEDVCFPQEGMSEIADDELNQARDQRSSMRRSRRRREKWPDLAILEEWSRIEKEGRSDERRIKKITEPQLINGRLRPIHKGWFRAEEDAPYRFTYFNEEFQSTIHSQTISELVQPDASFRELFVPERPILSDSSSDEDDELEQMPTITNSHLTSSLKNGEPLSKVPSMAFSNRETRNESTDTAHLSEHLPSSMPSRHQSGEATPMGFPMGFPMGFKSPTKSTSPKPEKPIRYGDRPVWWLDVLSPTEAEMKVIQKTFGIHPLTSEDIMLQEQREKVELFRHYYFVNYRSFDQDSESATHLEPVNLYLVVFREGVISFHFQQTPHPANVRRRIRQLKDYMVLSADWISYAIIDDITDVFVPLIQKIEEEVDDIDDAILMAHRGGDPDGEDGRQRDGRKDKDASEKKSIAGDTMAGEVPSDGDMLQRVGSCRKKVMGLYRLLGNKADVIKGFAKRCNEHWEVAPRSEIGLYLGDIQDHIVTMTSNLSHYEVILARSHGNYLAQINIRMNERSEQTADTLGKLTVLGTIVLPMNIITGLWGMNVWVPGQEYEGNLTWFWCITGGLLMFGMGCFFIAKRVYKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXS6</accession>
    <name>A0ABR1WXS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670860.1">
        <property type="nucleotide sequence ID" value="XM_066807242.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040302"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="25777" checksum="0E22FC4307E718DF" modified="2025-10-08" version="1">MELRPDADEWPSSGEDRWRKGPSLSIDEQQQRALWPDNGLCVSLSRNLKSKQGGEAGKARAKRDPVQCAVSMTHADNPTDGELEQRLPFGRTLGGGWVSAVQSHARTLTDNCCEGKGGRLQVPKRAGQDWTDCIEGDRLADGEALGTNYQDDEMPSAHFLHQPVRCCCGGVSFSAKDGLVGNVEERKRMRHKKISSVVVVVAAVAVAWPYLALARCFLWLGRAEFSKLSPGASWAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXU7</accession>
    <name>A0ABR1WXU7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl reductase LovC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670855.1">
        <property type="nucleotide sequence ID" value="XM_066807237.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040297"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="453" mass="49767" checksum="13960E5624699520" modified="2025-10-08" version="1">MAFSTSKANWSFPCTLPRPELFWLEPVKTAYVAHTYQKQDTSPNEQLVYNPSIWSPQINPPPGLGNAAQANPPPPGLGNAYQVNPSPGLGNGYQVSSRPGLGNATQINPPPGFGDFNVAGGQSQRSGNYPGVGNVGYPAPNDIWRPRPEPSNFVQQYPEATNPTGQYPERLNNWQQYPGSNAGMNQPPVSSAVGQPRELSGFTGQQPRANNTVGYRHGKNAVGQQRRAAYPLEQQSIRTQAAPATSPLEYDPNFTFSENYKGSRLSRSNFSANVSDQENCSVFIRGLPPTCTPDMLLRNIRGCGTKVFALHINEPDRKNPDHCAAKLVFFEPHGVDWLWEQIEAGTFIVADENGVEYKPNACPNKIRSAPISSEDQRTRVLLISGPASVVSAESLNRFFKANFRYEVDCVYTAYEDPNWRAMEFHFSSARNQCDNAVKALNRLAFSGPGPFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYC5</accession>
    <name>A0ABR1WYC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671062.1">
        <property type="nucleotide sequence ID" value="XM_066807444.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040504"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045712915" evidence="2">
        <location>
            <begin position="18"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="166" mass="17971" checksum="3A68BFF48F493A4A" modified="2025-10-08" version="1">MKFTGLVVPFLVAYAEATLPYNLRDTFGSHPRGVAEPRHFPKTYDGQHHGATGTGGYPHHHPTGTGYHGPRPTKYEGMLSGQRSSSVTDPNNGDGQAWGPYQGEYHHAPWPPAGKGKGQNHGTGILSFQPWPRPTGGYHHHPPGTGQPPKWPKTTLSTRTVSATHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYW7</accession>
    <name>A0ABR1WYW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003284</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671217.1">
        <property type="nucleotide sequence ID" value="XM_066807599.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040659"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="6"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="54"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="526" mass="57855" checksum="9621E4A7D9853EB4" modified="2025-10-08" version="1">MATTSGSVKIAPSGIAGAGRGLFACQKFEPGDVVASVDRPFVAELEMDRMEDTCAWCFQRGETDPDARAKAAMMGMPAGFIETKACAGCHRASYCSKTCQSRAWKREHKYECGLPESVRAAIKLLGRLKAADPKGAEHKKLLDLLMEFRPAGADTNLLETFKQQDKQKFDDFNMLAWAAWSYCGKPGNYGAVDSRAGATGFVFNILCNALTLASPVDGVKFGIGFDNTICAANHSCDPNVVMTFLQPKVELRALRPIKNGEEIFVKYVDVTNPIGVRQAELKQTRQVRRVSRGAPSRYFAIADMLIKKYDAQLSHFLASPVETATTAQKRVAAMEAEAFSISGTTLGGGESVESNEENARNALKMCLDSGMWSLARQPVPQLCRQLFQMYLEGGSPYRAFRIGLKAYFEILPKVSPQEFYPDRIIDTWGLATVTNVLCGPAFAEIYGELQASGVDLRVVFIGLLFEVYDQLPRMYGLASPFGKVMENTYKQIVAGMGMSEADLRDRVKQTWPSLETAARSIDLLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X062</accession>
    <name>A0ABR1X062_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD repeat domain-containing protein mip1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003718</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat RAPTOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671651.1">
        <property type="nucleotide sequence ID" value="XM_066808033.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041093"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029347">
        <property type="entry name" value="Raptor_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14538">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01547">
        <property type="entry name" value="YEAST176DUF"/>
    </dbReference>
    <dbReference type="SMART" id="SM01302">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Raptor N-terminal CASPase-like" evidence="6">
        <location>
            <begin position="228"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1363"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="969"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="969"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="980"/>
            <end position="989"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1481" mass="167350" checksum="931231BEBBDC4E0E" modified="2025-10-08" version="1">MSAVAHNGRGLNHQQHQHQLHHPPPATSSNPQSSPSQHNRRVSNLGASVSRAARFGPTPVAPSAMPSHPGSSSSAFAQYQQQPPPSRASDVANGQPNGVYEDDTDQDGDRRPSSAPGNKPRVSIATSFDDSDREQPRRRPKPPCCVPRASTFLGMKRQICQMKRCTNGARAMVLKTITSQRISSLSWQIRRRRWIPNWYMYYTDKRHETTGHPKSPGYTIEDWRMRDRLKTVSAALAVCLNIGVEPPDQLRTNPGAKLEAWTDPYGQKALENIGKALQNQYENISVRTRYKQYLDPSVEETKKFCISLRRNAKDERVLLHYNGHGVPKPTSSGEIWVFNKNYTQYIPVSLYDLQHWLQAPTIFVWDCSEAGNILTNYHRFVEKHEEEEETAAAADPSYEKVKFRSYLHLAACAAKENLPTNPKLPADLFTACLTTPIEMALWYFVLQNPLKTNLTPERAKKLPGRLQERRTPLGELNWIFTAITDTIAWTSLPRHLFRKFFRQDLMVAALFRNFILAQRIMMVYGCHPQSYPELPDTHQHPLWESWDLAVDLALAQLPMLERKEHEGIEFEYQSSTFFTEQLTAFEVYIARGNANAQNPPEQLPVVLQVLLSQQHRVRALILLSRFLDLGPWAVQLALSIGIFPYVLKLLQSAANELKPVMVYIWTRILAVDISCQPDLIKDSGYGYFSAIMRPSEGLVVANDEHKAMCAFILAMLCKGYRPGQVVCNQSNNSEKPEIMSSCLAHLGNEENPLLRQWACLCVSQLWQDFPEAKWRGIRENAPLKLSTLTKDPCCEVRASVVHALTTFLGIPDLTDEVARIEESIAWTLLDMANDGSPLVRKELVVFLSHFVPRYDSKFIVAAYEQLMEEKEYLVHPPQNEGLDYKLGLHYARQENRNADGTINPAVQGFSHNTVFAACWKHVLILAVDPHPEVQRDATIIVDYVHQALIDSPVSVQAKNLMDNIQRRVRKTGGQGHRKQASTSRNSMMHSNPADISAPEPSPGLLKRTASLLFSGIWGAEDRPYPSPPLASPGLVRSGSQKFRSAAEWIAPQEQNDPSTIASHYHVTEEPVSGGFEERSAKELPTLPLKSTLLDWSIEYFREPQMKPTEAEEPGSTEYNERLWRRSRNENILRETQPQKHYAGTHKWNNQLAIMNNGAQPAKMTFHQFEDHLAVADDGNTVNIWDWKKQHRIGRFSNGNPEGSKISDMKFINEDDTAFLMTGSSDGVIRIYRHYDSEKTELAASWRALTHMVPSNVNSGMVFDWQQVTGKVLVAGDVRVIRVWAAAYETCIADIPARSGSCVTSITSDQMTGNIFVAGFGDGAVRVFDTRLKSQESMVKKWKDDSDRQWIKSVHMQRGGQRELLTASRNGKVKLWDIRMDAPLKVVQTTRDTLRTASTHEHLPVFSVGTSAHCVKVFNFDGHELSRMEPYSSFLQQSRGAPISTTAFHPHRMILGCAARGDHHINLFTCAQETPQAYLNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0G0</accession>
    <name>A0ABR1X0G0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_003808</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671741.1">
        <property type="nucleotide sequence ID" value="XM_066808123.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041183"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18947">
        <property type="entry name" value="HAMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="50"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="142"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="234"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="399"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="473"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="843"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="975"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="980"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1004"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="7">
        <location>
            <position position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8088847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1043" mass="114516" checksum="B4E791ACD3EFC0D9" modified="2025-10-08" version="1">MMDQLQVFSSEVSRVAREVGTDGMLGGQAMIEGVDGTWKELTDNVNVMAQNLTDQVREIASVTTAVAHGDLTKKIERPAKGEILQLQQTINTMVDQLRTFASEVSRVARDVGTEGMLGGQADVMGVQGMWNELTVNVNAMADNLTTQVRDIAKVTTAVARGDLTQKVQAECRGEIFELKSTINSMVGQLQQFASEVTKIAREVGTEGRLGGQAIVNDVQGTWRDLTDNVNGMAMNLTTQVREISKVTTAVAKGDLTKKIGVEVRGEILDLKNTINSMVDRLSTFAFEVSKVAREVGTDGTLGGQARVDDVEGKWKDLTENVNTMASNLTTQIRVPAKGEVAVLKETINNMVDRLSIFCNEVQRVAKDVGVDGKMGGQADVGGLKGRWKEITTDVNTMATNLTTQVRAFGDITNAATDGNFTKLVDVEASGEMDELKRKINQMVYNLRDSIQRNTQAREAAEQANKTKSEFLANMSHEIRTPMNGIIGMTQLTLDTDLTQYQREMLNIVNNLANSLLTIIDDILDLSKIEARRMVIEEIPYTLRGTVFNALKTLAVKANEKFLDLTYRVDHSVPDYVVGDSFRLRQIILNLVGNAIKFTEHGEVSLTISKAENATVKHPNEYALEFVVSDTGIGIPQDKLDLIFDTFQQADGSMTRKFGGTGLGLSISKRLVSLMGGDVWVQSEFGKGSSFYFTCVVKLANGDLSMIEKQLKPYKEHQVLFVDRGRTRFGKEIVSILQSLGLVPVVVTQEGPSRDLGSDEPPYDVIIVDSIETARRLRAIDDFKYLPIVLLAPVVHVSLKSCLDLGITSYMTTPCKPIDLGNGMVPALENRATPSLADNTRSFEILLAEDNRVNQRLAVKILEKYHHVVTVVGNGLEAVEKVKEKKFDVILMDVQMPIMGGFEATGKIREYERSLGAQRTPIIALTAHAMMGDREKCIQAQMDEYLSKPLQQNHLIQTILKCATLGGALLEKNRERELARSTEQGNQHLQNGANVPRPSLEPRAITSTEPLGSITSPTLVTADQDDPLARARNASLSETCLATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0I8</accession>
    <name>A0ABR1X0I8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PrsW family intramembrane metalloprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671817.1">
        <property type="nucleotide sequence ID" value="XM_066808199.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041259"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026898">
        <property type="entry name" value="PrsW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36844">
        <property type="entry name" value="PROTEASE PRSW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36844:SF1">
        <property type="entry name" value="PROTEASE PRSW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13367">
        <property type="entry name" value="PrsW-protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="36589" checksum="9BDDE83882A43682" modified="2025-10-08" version="1">MTNTSTAAARPPSPAPCSSPAPLGSGPWASSSSSRCAPSWTSCSGARGRDYVREFLRSAGGRAHLEATLSAAEAADRAAMARDWRYGALCAFFGVVAAGLPEEALKYAPAAAVRWWRGRKQAETGEARRMSPREFVNYTVAAGIGFAVFENVGVVYGSVSGGNSTAEILLLLAERTFSALPGHVLCAALSGIRDSSTAARRRSADTAGEKGVVAGVVDMLSAILPSVLYHGVFDSFLLGVSAWCGHPGWVRPADPWVLACGYGVVVALQGLARPECPGGVEGRRNACAGGGVRQERWSQEGDLILFVKFMRSCFVLVSQLWHSLFLMHAVMSLSFSSHLYNSHSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1C8</accession>
    <name>A0ABR1X1C8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004131</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672064.1">
        <property type="nucleotide sequence ID" value="XM_066808446.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041506"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044554">
        <property type="entry name" value="ANAPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014786">
        <property type="entry name" value="ANAPC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057975">
        <property type="entry name" value="TPR_ANAPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45957">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45957:SF1">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08672">
        <property type="entry name" value="ANAPC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25773">
        <property type="entry name" value="TPR_ANAPC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01013">
        <property type="entry name" value="APC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cullin family profile" evidence="8">
        <location>
            <begin position="491"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="44"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="827" mass="93628" checksum="C9CF110272C8E658" modified="2025-10-08" version="1">MERGQAPRIPVRLPHQLLTANAHVHSIPRILGARTVFWGPLASTPQKKHADLPSSQEPRLPFSPENPHATDQTRFDRSWHAVTSRIALPPSVAAEDSFGPLPSPQDADDDGLFMSALHDILDPAGRLPLATHTEDILSWHTQQVRLHFVNHVVPLLSICDSHADQTQVLLGSTRTLEAAHRQYAFGMSLVLRGMEHGDADTALSKFRRDLHAIVGNSVSNPLMAALRSVLGRLMATVLGIYGAPKAQPRGAHDSPEVEEARREVLQLVESLYKIGLAGERFQILFAEILNELMITYLYKLFAGVWEKRTDPYAVHPRPRCVEQLMAWIEERYARLAVEVANQLGNVQVSWTDVEKWKEIAIGRLAALRITELFDIVMNWPDSEGAVEDLRYAVTTPRRRLQLTDAFSSALQRRLLHPGRSTLDILRTYISMIRTFQKLDHSRVLLDRVAYSLQLYLCTREDTVRIIVTSLLSSPKETLSEARKVKLVELAELLHDPNQSRSERQDDEWDDLNVIGTLIGALGSPEVFIKEFQNIIGERLLSDQVGFEQEVVVLDLLKKRFGESLLQACDVMIKDIQDSKRLDGVIHRGAVNHPDKVKHEWAIHTKILSRLYWPDMGEEPFVVPEDIVDMQKMYETIFQHLKPTRTLKWLNHLGQAKVELELEDRTISEEVQTYEAAVISAFSEHAVSGRSPSWTFEDLWMHLQMDEDLLAAALRFWEKKQVLRKLPSDEYVGAKGANAAASTPRKAKKPSGISEKEKEKRQVYWQFIVGMLTNSSPAMPLGQIAMMMKMLIADGFPWSNEELQEFLGDKIADGELELAGGKYKLIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1M0</accession>
    <name>A0ABR1X1M0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004252</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672185.1">
        <property type="nucleotide sequence ID" value="XM_066808567.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041627"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="7">
        <location>
            <begin position="365"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="8">
        <location>
            <begin position="1282"/>
            <end position="1589"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1638"/>
            <end position="1715"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1763"/>
            <end position="1840"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="4">
        <location>
            <begin position="1282"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="4">
        <location>
            <begin position="1440"/>
            <end position="1589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1720"/>
            <end position="1767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1720"/>
            <end position="1734"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="4">
        <location>
            <position position="1314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="4">
        <location>
            <position position="1501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2140" mass="230851" checksum="14EBFAFD56C40E41" modified="2025-10-08" version="1">MADQMAFLLFGDQSLDTHGFLADFYRLGNPSVLSKAFLEAAGEALRVEVEQLPRVERTKIPMFRTLRQLNERYHAQSIKYPGIDSALLCVAQLAHYIDRSEKEYQDATEPENTYLSGLCTGLFAASAIASSPSPLVAPSYRSPERLSPSSEKSESWTYVVPGAKESTAKSILDDFHKSEGISQASHAYVSAISASNIAVSGPPATLKSLFSKDLFDSRPTAIPVYGPYHAAHLHATADLDAILRLNDESVSAALADSKPRSSVMSCVTGASFTETDTKSLLKAVVWEILNEPLLFHKALSGSIGHARGFKGTRALVIPYGPTQAAGTLANLLKAQTQLEVVLRSPPAISRESNSASIGNHGSTGKCKLAIVGMAGRFPDSASVEAFWELLEKGIDAHRVVPADRFPVDSHVDPTGKAVNTSHTPYGCWIKDPGHFDPRFFNMSPREAFQTDPMQRMALTTAYEALEMSGYVPNRTPSTRLDRIGTFYGQTSDDWREINAAQEVDTYYITGGVRAFGPGRINYHMGFSGPSLSIDTACSSSAAALQVACTSLWVKDCDTAIIGGLSCMTNSDIFAGLSRGQFLSKKGNCNTFDNDADGYCRADACASIVVKRLDDALLDKDNILAVILGSATNHSADAISITHPHGPTQSILSRSILDEAGVDPHDVDYVEMHGTGTQAGDGTEMVSVTNVFAPAERHRSADRPLYLGAVKSNIGHGEAASGITALTKVLLMLKKNAIPPHIGIKGEINKTFPKDLGDRGVNIAFHKTPFQRRDGKPRRVFVNNFSAAGGNTGLLIEDGPKYPAAAADPRSVHIVTVTAKSKSAMIRNAENLVRFIEENPSTPICDIAYTTTARKIQHYWRMNVAASSSSDAAQAIKERLKSNFVPVSPEQPKVAFMFTGQGSHYAGLGKELYAHYSVFQAAINEYDQLAQIHGFPSFLPLIDGSEPEVQKLSPVVVQLGLASFEMALAKLWASWGIQPGVVLGHSLGEYAALNVAGVLSASDAIYLVGARAQLLVEKCTAGTHAMLAVQGSREVVTEALGDRGATTNVACVNGPRETVLSGTSTEVAEIAEQLGAAGFKCTQLKVPFAFHSAQVEPILDDFENLARSVRFGTPKVPIISPLLGKLVDGEPINPKYLRDHAREAVNFLGGLVSAQKSGIIDEKTVWLEVGPHPVCANMVKAAFGATTIAVPTLRRNEPTYKTLSASLCTLHSAGLNLDWNEFHRDFDQSVRLADMPTYSFDYKNYWLQYTGDWCLTKNRGALPAASMKAIEPAKPALSTTTVQKITREDVKGDVAILECESEMTREDLRKVCSGHLVNGTALTPSSLYGDMAITACEYAYKLLRPEAENIGCNVSHMEVPKTLIFDTKAKSQILRMSVKADAAKGYADLTWTTGEGAQKAEHANCKVYFGNNDEWLGEFDRVSYLIKSRVDALRAAEQRGDASKIGRGLAYKLFAALVDYDQRYRGMESVILDSATCEATAKVVFQTSPEDGTFHTAPYWIDSVCHISGFILNGSDAIDSREQVYISHGWGSMRFAERLSATKTYQTYIRMQNIKGTKMMSGDAYIFDGDKLIGIAGDVRFQAIPRKVLNIVLPPQGVAAAGAAPARAAPVAAKAAAKAPTKEKKQVTSSNLPAVNKKLSKTSVVAQVMEIVAKETGVSHDELADNIAFSDLGVDSLMGLTISGRLREELELNVDSHAFNDYATVGAFKAFLAQFETAGSATAEESTDSSGSSETADLETDSDVTTPPDESDKGSVKGDAPSDSNVGELKEIVRNTISAEMGVEVEEIIAAPDLAALGMDSLMSLSILGILREKTGLSIPADLLGHNPSLKDIEKALGIEDKPKRIAAPKPAAPAAPKPAAKSQEVVKTQSTTVDNYPHRKATSVLLQGNHRTATKQLFMIPDGSGSATSYTEISEVGPDVAVWGMFSPFMKTPEEYKCGVYGMATKFITEMKRRQPKGPYAVAGWSAGGVIAYEIVNQLTKANEEVSNLIIIDAPCPITIEPLPAGLHAWFASIGLLGEGDSADAKKIPSWLLPHFAASVTALSNYTAEPIAKEKCPKVTTIWCEDGVCKLPTDPRPDPYPTGHALFLLDNRDDFGPNRWDEYLDVDKMSFHHMPGNHFSMMHGDLAKQLGSFMRDGMKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1U4</accession>
    <name>A0ABR1X1U4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional repressor tup12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004355</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672288.1">
        <property type="nucleotide sequence ID" value="XM_066808670.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041730"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013890">
        <property type="entry name" value="Tscrpt_rep_Tup1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08581">
        <property type="entry name" value="Tup_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcriptional repressor Tup1 N-terminal" evidence="9">
        <location>
            <begin position="16"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="316"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="351"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="392"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="437"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="490"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="532"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="126"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="35"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="570" mass="63031" checksum="9E111F8A4389910A" modified="2025-10-08" version="1">MSMYPHRGLPQNAAPRLNELLDQIRSEFDAQVRLNEGYEQQIQQQVQEAQLVREKVYQLEQQHMTIKQKYEEELVHLRRQLDQARGGAPQQGMPARLASRLSRLPRSNKHHQDPLIRCSLLRVFRARLPPPPPPSQQPPFAQPYQQGPAPNGFPGQPPQSTASPGPGAKRAIGRPPTGPATPQINTPMPYPGPGASPQVQNHPTPDHRGGPMPPHPGPVVNNALGDLDPDRLPAHVKKTRDDWFVIFNQQVPRMLDVDLVHTLDHQSVVCCVRFSHDGKYVATGCNRSAQIYDVTTGEKVCVLQDENADVSGDLYIRSVCFSPDGKYLATGAEDKLIRVWDIQQRTIRNTFSGHEQDIYSLDFSRDGRIIASGSGDRTVRLWDIETGGSLMTLSIEDGVTTVAISPDTKYVAAGSLDKSVRVWDIHAGYLLERLEGPDGHKDSVYSVAFSPNGRDLVSGSLDKTIKMWELSAPRNPANAPVKGGKCVKTFEGHRDFVLSVALTPDNNWVLSGSKDRGVQFWDPRTGFTQLMLQGHKNSVISVAPSPVGGYFATGSGDMRARIWSYRSLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2D1</accession>
    <name>A0ABR1X2D1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA polymerase theta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004529</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672462.1">
        <property type="nucleotide sequence ID" value="XM_066808844.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041904"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18026">
        <property type="entry name" value="DEXHc_POLQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057220">
        <property type="entry name" value="DUF7898"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046931">
        <property type="entry name" value="HTH_61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048960">
        <property type="entry name" value="POLQ-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF6">
        <property type="entry name" value="DNA-DIRECTED DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25453">
        <property type="entry name" value="DUF7898"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20470">
        <property type="entry name" value="HTH_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21099">
        <property type="entry name" value="POLQ_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="140"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="385"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="929" mass="102691" checksum="3E7321C7B2C87FCB" modified="2025-10-08" version="1">MASRQGVFHHTTVQNVAQQHNAYHTTAVTGTKRSFSTVDVHGSNPQALVDRTGFQRASSVSAATPRLRASAIDATDPGAGQEISEYSQRKAISSTPTSYVDRALQLSHPRYALPENLITNFDSLGIKDIYPWQKQCLMGPGILTGEKNLVYTAPTGGGKSLVADVLMLKRVLADPDAKALLILPYVALVQEKVRWLRNAVQEIRRKEPEGASEKADEGTIRVVGFFGGGKVRATWADFDIGVCTFEKANTLINTAIDDYSIVKLRAVVLDELHMIDDDHRGYLLELMATKLLSLEQNIQIIGMSATLSNIDILAKWLDAHTYQTFYRPVPIEEHLVYESKIYASSATGSLLKAVGQLAPNALPSQSTSTHLRLIRPSDHKEFKDPVLNAVVALANETVRSGYGVLIFCSSRPGCESDARLIARVLPDLYEIDQSISEQRSDLLGELRSLPTGLDPSLADTIPFGVAFHHVSMEPCCLHRSLTGIQAGLTIEERDLLANAYDSGVLKVIVATCSLAAGINLPARRVILHNARMGRDLVGPSMLRQMRGRAGRKGKDEIGETYLCCRKADLEEVIGLMHAELPQVCSGLMTDKHRIQRALLESVAIRLATGRDSLEDFVRRTLLNQTESSSTVQSHVESGLKDLSEMGFIEFDDSGNHQATQLGKAVVASSLEPEDGAFVHRELQRALRAFVMDGEMHILYTFTPVQDFSITINWKVFRDELERLDESGLRVLTFLGLKPTMINRMAQGGKMKVSTPEEKELARVYSRFYLALQLRDLCNEVPIHIVARKFDVPRGTVQTLAQTCQGFAAGMIKFCQLMGWGVMAAVLDHVADRLKAGAKADLLALAQITFVKSRTARVFYENGYKSVAAIANADPKELVPVLMQAQPTKLRLKEKDEQKYEEKLLAKANVISDSANRLWQIEMQQEIDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2H0</accession>
    <name>A0ABR1X2H0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004552</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672485.1">
        <property type="nucleotide sequence ID" value="XM_066808867.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041927"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047327242" evidence="2">
        <location>
            <begin position="17"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="389" mass="43901" checksum="09A5CDE9C67F64B2" modified="2025-10-08" version="1">MTVSFIITVYLDALLAWVLEPRSQREAITDQTTGSTGVTTTGADEVSAPGVLEIQEASRLPTPTPLSPEQRRTLDWVHRGSHDDSSYTFDYAQDVHRLEATVPDRPQSEGSEPRQTETEEAINQDTVITLDNNDGEVESTAQVGFPEEGTTEDVVEIGPGEIQDKGASSHTDEEEETDPVTIERPTTSLSFHPEDERSDDDDEEVVATRPTVDINKEYELPHPDTEEEKEVVVADVFKEQAAEAAPKEVVEDTPEEDTAEDNVEIIPVLERTTQKRPHRDRRDTKRDELMELRSKLEFLQALRGREKESRAVASSSTTTTATRQQQQKQQKQKQKQQKKKEARDNHVVHERPQLSEQRRAELVDLRSKLTLFCENARATAAGQRRSCHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2R4</accession>
    <name>A0ABR1X2R4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7603 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004664</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672597.1">
        <property type="nucleotide sequence ID" value="XM_066808979.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042039"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056023">
        <property type="entry name" value="DUF7603"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24554">
        <property type="entry name" value="DUF7603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7603" evidence="3">
        <location>
            <begin position="842"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="409"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="597"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="957"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="442"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="643"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="661"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="959"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="978"/>
            <end position="994"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1107" mass="123223" checksum="DA5D5E196E4859BD" modified="2025-10-08" version="1">MDPVDDEYVPQRRPSLTSTSETLGASSDVPFPPTQSLYRDQVATARNTRKLVIDSSATVPPLNTPIRRKPVSKTASPIVSRYSSGEYLAVTRNLQRPEQRYSRSFSLDSPTVYEFPLAVRKSPVPLEKSPVLIELPPKTVAHRTPGDCKKTLSILEDFPLPMQSDKAAGLSEAKQPRSPDSHDNPAAPQPAATAGLTQPNDPADFEDPLPADEDDDHLSVLDGYNSDSSGQSNYNPTPVTPERNMSLFVNRKPAPPHLTLSQINTEEHTATAPSPSNSNHEARSPNTDKPLPKSPGSSSSKLGTFFSWGSPSPSTTEFSPLPSPYAPSKSNTTYTDASPVTTIRPSSLLEAPKGSAGSRESGESYLAAPPAILPNHPAEIEEMEEELKAISAELASSIRREMDLEDLVDRLQAEKDNPASSSNNKRTSDYFSDSGYSSTKFSDYDQSKEEVERIQRRAEQEMASVRLELTNKLQDERTRRQQLDDQIKDLSKRASQLDLEQLSNADDSDRVKDLESTCETLRRKLTEERQVKENFEDLLTVLKGELQTAANERDNLRDEIVPQLRARVEGLEAQATDLEKMSYESTKMQQELQSLKSENTNLKQEKEERSIGSIAEDTSRMSRSSSVTGPPPSFRLQRPPSVSKTPSLSRSASLSRSKSVKTTESRDALSDRLKDVEEQRDALHRALKALLERQECQNRENEKKIRSLESERERLLSGSPQKAGFVKEVSNLREEINTLRRRSEEALEQRWQVEKNLAGLKMDLDRAEQEIASLRSLLDEKDILIPENLSRSSAYSDSSAEPVTSDSLRAAYRDLQEAYAQSLERIQSLDSGSTHDEKTQLAIEKLQQSLSSAVAERDLAVQEVSSYKAQLDALKAQEQTYLDSEKTLADELQESARRVEELALQVRQQLASNQNLRQRLTDTVSRGEAAQKANAEHITALQARLRTLEEQVVAAQTASEERVSRHEDELTTLKESHSQQLSRLSSNLSPRSPRMFPPKSPMSPLFAGAGAKSPRLDMTRSGSAMSVAEETQVAALREKVAALEKALAEADVEMQEVVSRMNTAQIEVLQLQEEREAAVNQARKLEKALQAEKVRAFEERFKSLQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2Z0</accession>
    <name>A0ABR1X2Z0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004665</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PurH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672598.1">
        <property type="nucleotide sequence ID" value="XM_066808980.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042040"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01421">
        <property type="entry name" value="IMPCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024050">
        <property type="entry name" value="AICAR_Tfase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005492">
        <property type="entry name" value="PRK07106.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692:SF0">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="586" mass="64608" checksum="8DEBBB7C02BE1875" modified="2025-10-08" version="1">MAQRIAIVSVYDKTGLLDLAKGLVQQNVRILASGGTARMIRESGFPVEDVSAITKAPEMLAGRVKTLHPAVHAGILARNLESDEKDLAEQSIDKVDYVICNLYPFKDTISKINVTVPEAVEEIDIGGVTLIRAAAKNHSRVTILSDPKDYPEFLKELKAGEIQETSRNRYALKAFEHTADYDDHISAFFRARYAGDGAQHSTLRYGANPPPEARRRFHALGRFALQGYINLLDALNSWPLVKELKAALGKPAAASFKHVSPAGAAIGVPLTDEERKVYFVDDIEGLETSGLAQAYARARGADRMSSFGDMIALSDVVDVPTARIISKEVSDGVIAPGYEDAALEILKKKKGGKYLVLQMDPEYQPDPTETRTVYGVTLQQHRNDIEIKPSSFSRTITPKDFSLPETATRDLTVATIALKYTQSNSVCYAKNGQVIGLGAGQQSRIHCTRLAGDKADNWWFRFHPKVLDIKWKKGTKRPDKSNAIDLLVSGELPKSGPERDLFEAVFEELPAPFTEAERDEWSSKLRDVAVSSDAFFPFVDNVYRAARSGVKYIAAPGGSQNDGAVFETAEKLDIVFVEQNIRLFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X339</accession>
    <name>A0ABR1X339_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-loop-helix dna-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672643.1">
        <property type="nucleotide sequence ID" value="XM_066809025.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042085"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46266">
        <property type="entry name" value="TRANSCRIPTION FACTOR TT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46266:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR TT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="135"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="354" mass="37526" checksum="D202258D0FCDA704" modified="2025-10-08" version="1">MPPTPNSSTEMKGKDGVQQMTSMQMSFELPPSAMGGKDAARPASSESKTSSPAASSFQPSDSKTTYPVQARAIRITAATDKVAEDHSDEASCPGRSCRAPSPAATPGAAGKVAAATAASKKKQPAATSAAGRKIARKTAHSLIERRRRSKMNEEFAVLKDLIPACTGEMHKLAILQASIDYVRYLEDCVAKLKSQNESQSSARTPTEFALPPPISRNVYQEDDLGDVEMTGSEAPSPTYTPSTSRSQRPSESPALLAEDARHRQNSYSSVSTDHRHYSYSASTQASPAFGPQQYNYNFGAASASNSTLTSPALPPLRDMDQEASAALLMLNTDRRGTSGSGAGRGMSVRDLLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3T8</accession>
    <name>A0ABR1X3T8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HpcH/HpaI aldolase/citrate lyase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672938.1">
        <property type="nucleotide sequence ID" value="XM_066809320.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042380"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="91"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8090044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="324" mass="34637" checksum="7DD671BC3DE7317D" modified="2025-10-08" version="1">MALPSQDTTSVHGYALRAPQSLFRRLLSTSLRLPSLVPKRVPFRQFQTRALSNNMLQGCKAREALANSDGASLGLWQTFPGANISRTLARSDGIDWVMVDCEHGNIDDAAMHEAVPAIASCGVSPLVRLPDMQGWMIKRALDAGAHGILIPLLRSAEEARKVVAAAKFPPVGQRGLGSPFAMERFTPVPTMTEYLQTANDSLLTMVQIETKEALEAVEEIAAVPGVDLLFVGPFDLGNNIGLPILDGVMEPGLEEAIDRILAVAHVAGKKAAFFATSGPQAKKYADKGFDMISVALDATALQQTMSVSLNSARGLDAPSAEGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9E5</accession>
    <name>A0ABR1X9E5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674094.1">
        <property type="nucleotide sequence ID" value="XM_066804321.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037381"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="490" mass="54625" checksum="BDB04E2511E1A3C9" modified="2025-10-08" version="1">MKPTVLGLNPKQDTPERILEILGWQGLKKDSIDQKLGFLSLGISTTTESSLDMSDVGSPLSLVVSGASSVHGFFGFTEPASQDLSTTGSSAASSDASTAASSCGDDSDGAEDDLGGAPSWPIHDLEVVVRLVVFSYILSKYKAFSYYNGSPNGKLEPQVADELTMQLVQPHWGNHCKRPGLRRIENEFREMQIWLSDMSCEWLQSLARGSSIRPSMLSLVREVTRVSKLGLKSVACFPGYILQRETLTRQGQTLILVDRHFCSQGTHLNVFTATLAADDETDMQCHQDSINEAHDATIQTKGIEGPSIWRIWQTSVEELMALRDPTTPHMVVMGNSINGSYKAYTDLVYSSLRDETKPQRTREHREAEEAQHCRAQHCVANEEHVEVFLLADHDKLALSFFAIHPRGEEDVDRFIHDKASDWSAQHGQQLWRLWQECHADADQVGTGEGYMGTFRWQHAFLESKGRLGALLRRAQMEDDLMPLKAPIKCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9T5</accession>
    <name>A0ABR1X9T5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674178.1">
        <property type="nucleotide sequence ID" value="XM_066804405.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037465"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="340" mass="37119" checksum="EF5D694AE7163934" modified="2025-10-08" version="1">MGDANPEPTPAPEPAPPEESPVESHDESDPESDWDPNQPFLVSNDKPTVLITGCSDGGIGSALARAFWDRGYHIYATARHVGNNMQAVDCLSDVAMLQLDVTKPEDIRKAVEVVEMQTGFRGLDILVNNAAQPHFMPLLDEDLDQVRQKFEVNYLAPLAVTQAFAPLLMRAKGTAVFVTSIAGYVNIPYLGTYSALKRAEEFMAETLRHELKPFGVDVMEIVTGAVQSKGQTHFDDFVLPEGSVYKPIEYVIKARAQGHDGVTRMDTMEYARAVVDEVLASPERRTKGRVWCGAGAEMAKGMMVPAGWDQEAMDAIAVKGQGLEELGKEATLEVRGGKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA48</accession>
    <name>A0ABR1XA48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674294.1">
        <property type="nucleotide sequence ID" value="XM_066804521.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037581"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="211" mass="24003" checksum="327636A4BAF13038" modified="2025-10-08" version="1">MEPISLTTLGAIASIASILNHGSDLVKKFRKRRKERKKAKENKALQKSIKSSHARNRQAYDDAVRLLEQRFGYNDDISKSQFRLTSSKMRRWIDLTLASSRDEVAIVFPKAILLRSMSDEIQSSVRSDLPGLSQRMMQATPIRNFAFNDSWIWDGPTIGGNRCSGMDPIEYIDPRIWNKPSNGGNRSSDMGSYYPNNEYYPQTPKIVPKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAV9</accession>
    <name>A0ABR1XAV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674506.1">
        <property type="nucleotide sequence ID" value="XM_066804733.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037793"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16963">
        <property type="entry name" value="CCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039197">
        <property type="entry name" value="Mrs1/Cce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015242">
        <property type="entry name" value="Ydc2_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28072">
        <property type="entry name" value="CRUCIFORM CUTTING ENDONUCLEASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28072:SF1">
        <property type="entry name" value="CRUCIFORM CUTTING ENDONUCLEASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09159">
        <property type="entry name" value="Ydc2-catalyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="380" mass="42265" checksum="01495C279BBDD5B1" modified="2025-10-08" version="1">MTAPAVYRVPAALAASTSPLKVVDYALKAVQLKTLCLACGLPTSGTKDVLTSRLEEAVLAARRPKGRPTARRILSIDMGLRNLAYSLIVPSGPLLSAPSPSTLKEKHFTSSQAFRQPPRVLLEAWRRSDVASEATKQVVEREQWAPAALANLALELVRDRLLPTNPTHVVIERQRFRTGGSSAVQEWTLRVNTLEAMIHATFRTLKEMGHWSGEVISVAPGRVGPFWVGAAGEVDAATEEVQSPLELETEFLERTAQKVNIKNKNKLAKTRNKKAKIDLVGNWLQLEGILNPASAHQEVTRTMKLYKDRWLGVRRKKGSNLLEEAEEESRKLDDLADCLLQGMAFIKWEENKNLLAREGPNAILETPQEAFRTVMHYDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAY9</accession>
    <name>A0ABR1XAY9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 70-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000438</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674526.1">
        <property type="nucleotide sequence ID" value="XM_066804753.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037813"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10230">
        <property type="entry name" value="ASKHA_NBD_HSP70_HYOU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF3">
        <property type="entry name" value="HYPOXIA UP-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047167959" evidence="5">
        <location>
            <begin position="27"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="594"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="805"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="923"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="594"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="613"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="805"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="930"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="940"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="961"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="991" mass="107501" checksum="F5C631F20E4ACA95" modified="2025-10-08" version="1">MVQLSSPRSLLLCVAFLFSTNVSAIAAVLGVDLGTEYIKATLVKPGIPLEIVLTKDSRRKETSAVAFKPFQNAPKSGAYPERAYGSDAMALSARFPSDVYPNLKTLLGLPADDAQVSEYLARHPALQVEKYKGRDTVSFKSKVFTTEEDSWMVEELLAMELQSIQRNAESLAGSDTLVRSAVITVPPFYTVEEKRAVQMAAELIGLKVLSLISDGMAVGLNYATSRQFPNINEGAKPEYHMVFDMGAGSAKATVMKFQSRTVKDVGKFNKTVQEVQVVGNGWDRTLGGDALNYLILDDMVQQFVESPAAKKASVTIDSVQKHGRAVAKLLKEAEKLRHILSANTESRGSFEGLYEDIDFKYKITRADFEKMAEAHAERVGAAVQKALDAAELDVSQLDSIILHGGASRTPFVQKALEKIAGNEKLRSNVNSDESAVFGAGFRAADLSPSFRVKEIKALDAAGYAAGMKWTSPQGKAQQQRLWTERSILGATPKEVSFTNHEDLTVKFYQSIPSADGVVDKETKTFTTKNLTATVAQLVEKNGCKNEDIQFKVKLQLRSEDGEVDVVKAHVECEAEDTDKEGSVMDGVKNLFGFGKKDQQPLKDGEESSEDAETASTTASTDTATTSSIESSTTTSTETGSASAESTDAAKPKKTIVVPVDFKLEKAGVPELSKDGLGSAKSRIKAFEMSDKSRRAREETLNQLEAFTYRVRDLLDSESFVATSSKKERAALEKKAGEVSEWLYDDGADATRDELKSRLKSLKDMVSPVEKRIKEKSERPELVKSPATATFIETIRKQIAEAEAWSSSASASAASATSGEASSVTAAPSKGSDDFDGLEDDAAASTTTTATPEDVGPVPVLYTMDDLKEITDLSKSTLDWLEKKLAEQAKLPETADPVITVDEISKKAKKLEQVGMQLAMKAVKNFDSKGGKKSSKKSGKKSGSTKTGTAAGSEQTIDADEIEKMVKKMAAEQAQKDKEQEKNKDKPKHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBG8</accession>
    <name>A0ABR1XBG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DUF1772 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000698</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the anthrone oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674786.1">
        <property type="nucleotide sequence ID" value="XM_066805013.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038073"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013901">
        <property type="entry name" value="Anthrone_oxy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042">
        <property type="entry name" value="ANTHRONE OXYGENASE ENCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042:SF3">
        <property type="entry name" value="ANTHRONE OXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08592">
        <property type="entry name" value="Anthrone_oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047128468" description="DUF1772 domain-containing protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8094013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="17076" checksum="EB7DFDBCF96A6A59" modified="2025-10-08" version="1">MTLAATPLNIAALGCIISGSYASGVGMSPSLLTMPALIRPDVPQDALVHQWHSMYRRGAAIMPVLSGATTLGYWVWRGFAAAGALTLAILPFTLVIMMPTIHTLEASMDGSAAVVDEKGQRRATMSRGTAEALLRKWTRMNVVRSLIPLVGAACAVWNLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBJ8</accession>
    <name>A0ABR1XBJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674843.1">
        <property type="nucleotide sequence ID" value="XM_066805070.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038130"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="81" mass="8949" checksum="A6B3E6758B3E5E10" modified="2025-10-08" version="1">MGQAMHGLWVRVARKTQKTQKNYAEQRTARKSIITSIILFRPLNPPLLLLWTKASSSSSLSPSPSPYRAQVPTGAESGELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBQ7</accession>
    <name>A0ABR1XBQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sm protein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_000749</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674837.1">
        <property type="nucleotide sequence ID" value="XM_066805064.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038124"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01722">
        <property type="entry name" value="Sm_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034100">
        <property type="entry name" value="Sm_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="7"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8094064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="85" mass="9641" checksum="E7EFF8E0ECF1AB1E" modified="2025-10-08" version="1">MSFMPINPRPMLQDLVNKDIVVRLKWGETEYKGRLVSIDSYMNIQLTGAQEFIDQKFTSDLGQILIRCNNVLWIKGAGQGRAAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCL7</accession>
    <name>A0ABR1XCL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein root UVB sensitive/RUS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001003</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675091.1">
        <property type="nucleotide sequence ID" value="XM_066805318.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038378"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006968">
        <property type="entry name" value="RUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054549">
        <property type="entry name" value="UVB_sens_RUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770:SF31">
        <property type="entry name" value="RUS FAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770">
        <property type="entry name" value="RUS1 FAMILY PROTEIN C16ORF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04884">
        <property type="entry name" value="UVB_sens_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein root UVB sensitive/RUS" evidence="6">
        <location>
            <begin position="40"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="396" mass="43346" checksum="79829258519CBBA1" modified="2025-10-08" version="1">MERSGLKVVGVVDESGHVVCAYRKDENKDDSWRAVPQKKTVSNYAKALFDIFLPAGYPHSVTLDYKPYQIYDSLQAFSSSIAGMLSNRAVLQGMGVGDAGSSATGAVLLSVLQDSTGRLATIVFAHRFGQAIEPECKFYRFAADLFNDTAFLLDVLTPVLPTYPKIMALCAAGILRSLCGVAASAAKASLSAHFAKNGNLAELNAKDGSQETVITLMGVLAGSLFVRVVEGRQAVWCWMFILIGIHLWTNYQAVRSVQMRTLNRQRASIVVDEYLHTGVILRPDQVARSELILLWKAPPICFCQTFPQEMQLKDSDMDCLNNKNYFITTCGTSPEKTIILREGATSRDALRAYMEALANGDDKVDEDQFWQALSSAGWDLDSGAAETGPAMRLVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD87</accession>
    <name>A0ABR1XD87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675393.1">
        <property type="nucleotide sequence ID" value="XM_066805620.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038680"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="73" mass="8058" checksum="CD808955409EB8E0" modified="2025-10-08" version="1">MEVWMEIPSVTVTEVTGQEPQPQGTNTTTTAALRGGSEDVYGDYYDCCEGCCSTMVICLRCWLCCGCHYDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDD1</accession>
    <name>A0ABR1XDD1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">ERCC4 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_001312</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EME1/MMS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675400.1">
        <property type="nucleotide sequence ID" value="XM_066805627.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038687"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20085">
        <property type="entry name" value="XPF_nuclease_Mms4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033310">
        <property type="entry name" value="Mms4/EME1/EME2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047521">
        <property type="entry name" value="XPF_nuclease_EME1_ascomycetes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077:SF5">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MMS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077">
        <property type="entry name" value="EME1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0469">Meiosis</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="15">
        <location>
            <begin position="389"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="89"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="516"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="332"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8094627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="703" mass="77913" checksum="17F60A8131D1CD9E" modified="2025-10-08" version="1">MPAEVIDLISSSPPPPSLQPQRVAFASSPPPLRRDSAHDKHHVNDILDSKDVVSVETLAKRAEATPVQPTEKHDNDFLFLEDEFDVTGDLDGFDSASNRERSSNDAKARSSYNRSSTWAAATGARAAGTSGPMRPTSFGRWNSIADPIENSSSPVAFDLTRDDARETSRLPEPTRVGKSSTKLTSAVATSKPTRESTENAPISSDPFADDSPIRPKPTVDVDLDIPSDLSFVSPVKSKKNAAWDPISSSMPETNTKLGSSPEKAKNHQPLKRKAEVLVIDDDDDDSEDELPDLSAVDFSKLKHTARSLSESPRKATKAQAQAPKKAVAMTSEQKEWEKRRKEQAREAEKERKRIEKERAKEQRAQEKATQKALDEVNKLRTDKKASTSEMIVDLPQSFAPAINLQVNKILEDLEVQRGSWHSHPVDHIVKWRRKVQSRYNEDLGYWEPVPLRIAPENHVLVVIEAPEFVKLALGSEGHDLDSHVLKMRTHFANETIIYLLEGVELWKKKNRNARNRQFTNAVRGNGEDAPPPSGQSRRRTAAAAHEIVDEDTIEDALVALQLHPGVLVHHTPIAVETAQWIAVFTQHISTIPYRKVKDLTAASAGFCMESGQVRTGDSPNEIFVRMLQENARITAPMAYGIVNKYKSVSELVRGFEAEGPLALEDCKKSANKDGALTDRTLGQAASRRLYKIFTGRDEGSTDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE27</accession>
    <name>A0ABR1XE27_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fungistatic metabolite</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675728.1">
        <property type="nucleotide sequence ID" value="XM_066805955.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039015"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF105">
        <property type="entry name" value="COPPER RADICAL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046381634" evidence="2">
        <location>
            <begin position="31"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="38"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="145"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="269"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="386"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="966" mass="101947" checksum="7D76A465D571D7BE" modified="2025-10-08" version="1">MASLRSLAVASVALLAQIATAGIIIPRALSIPTDLPNNWTYVACYIDNADGKRALGGDGYNNGTSMTVEDCALFCMDKGYSMAGTEYGAECYCGDKPNEASTIVNDSECSVPCAGDATQPCGAGNRLSVYSGPAKTPMPPAAIGGWKYEGCYTEGTGGRTLTFGAGVPGGSAAMTNNLCTTACRQAGYTIAGTEYSGECYCGNEYANGGAQISQGCNMACNGDSTQICGGGSRLSVWSLIGSGSNPTSTISTRPSQPTSPGSPAALPAAWAYKGCYTEGSSGRAFLNQQPDSQTLSVESCVEKCVSLGYGVAGMEYGAQCFCDNFVRNGAELVSDSDCSMSCSGNPAQKCGAGNRLSVYSNATLIVYQPPKPQTENLPANWAYNATISECIAGCSRFGYEAGGIEYGYQCFCGDVPLGSKATLLPETECNVACPGDPQILCGGGNRISYYRWTGPQLTKWSYASGPAAGRYDFIMSAPLIPLISTVGINDKVVFVEKHGTGEGNHTGSFEFDPSLAPQYGTAFRELQLKTDVFCSGSIVMPDKAGRQINLGGWSLDSLYGVRLFTPDSPLGTNGTNQWEEDYTKLKLMDGRWYPTALTLSNGSILVMGGEDGSDGPMVPSAEVVPKPAGVTASTHLDYLANVEKVNSYPFVAVMPSGNMFFAQYNEARLISQVDFHSVRSLPKMPGAVNNPDAGRNYPLQGTMMLMPQHAPYTDPMTVLVCGGTTDGANFGIDNCISTEPDNAGAQWRIERMPSTRVVSLMVALPDGRYVIMGGSYNGRAGFGLQPDPPNLSAVLYDPTKPLGARMTMWANTTIPRLYHSEAVLMSDGRILVSGSDPEDAKHPQEHRLEYFSPDYILSGDWAYGATVNFQLTSTSGGAIRVSLLAAVGSTHGNSMGQRTLFPAVTCNGNACTVTAPPNANVSPPSWYQMFVLDGPTPSQAVWVRIGGDPARLGDWPQIPGFTHPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEJ7</accession>
    <name>A0ABR1XEJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Manganese lipoxygenase</fullName>
            <ecNumber evidence="3">1.13.11.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_001713</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(9Z,12Z)-octadecadienoate + O2 = (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate</text>
            <dbReference type="Rhea" id="RHEA:18993"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30245"/>
            <dbReference type="ChEBI" id="CHEBI:57467"/>
            <dbReference type="EC" id="1.13.11.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.45" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675801.1">
        <property type="nucleotide sequence ID" value="XM_066806028.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039088"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.245.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000907">
        <property type="entry name" value="LipOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013819">
        <property type="entry name" value="LipOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11771">
        <property type="entry name" value="LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00305">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00087">
        <property type="entry name" value="LIPOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="Lipoxigenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51393">
        <property type="entry name" value="LIPOXYGENASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoxygenase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8095028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="596" mass="67270" checksum="F664A7A9AC05CF1A" modified="2025-10-08" version="1">MDTANFEPTMPSPLTPNQKKMFFVFTDPVSDNYPPHLNLGANQLEPKDSAGAKEQGSGLDKDDIFSALRLAQLTTLLPGLIPDDFIDQAKAKIGQGAGLRCYNNYESSKFWYQKDIFDLPNIGNLPDWYSDARFAQQYFTGTNPTTIRQAGSWAQTFIDAATHPRDSQMKAKISQRVQNSPGSLYVQDYSYFRGAAGTQEFRCAYGGGDVPAGFRYALASVCLFNLTDSGTLEPLAILIDSVKNNDERVFIYNKELTVEEQKYDWPWRYAKTCVQASDWIQHNITVHLCRTHLVEEAVIVAANRTLPQDHDVYQLLYPHCLKTLSLNAAARAVLVPNVIVPIMGMKKEHTRGFPTGQQLYDDPKYHNYAWARCIHSMWYKIRQYVQDMLVIKYGLDAAAADQAVRADEDIQAWSREMRAPVEEQGANLHTFPKLESFEALVDCVTMCIHIASPQHTSVNYLQNYYQAFVVNKPPALYQPPPTSIDELLNYKESDLVAALPMNHPQDWLLASHIPYLLSFKPGDKESLIIYAASKYHVYKYKAGDRAQKIKVAAARFYEALANSEGEFKGYGLATDDHQTITYDVLSPSWNAVSILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTU3</accession>
    <name>A0ABR1UTU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_014445</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660947.1">
        <property type="nucleotide sequence ID" value="XM_066818759.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051819"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF26">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G07710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="185"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8062348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="469" mass="52662" checksum="192C26EAD5EB1418" modified="2025-10-08" version="1">MTSRRGDTIITLPNNQQYAVPSRGGGGLGPVIPTDGMMPEKQPRNNAATAASAASVRALTSQAIAFYFRAPVKAFFRTRVDYLAYARSVHHAQAQLHVRPLGSDRATSRLTAALQQTWTWMRATTPGVLTSAVRHDGWAVIPHQVLPPLIANVSVGAVLYTSYLQILGRLHPESARGNKRAYPPPEPIQTFTAGFLAGSIQSLLAAPLDAIQARYDHRDLMPASGKGKPRSMWSFSAEKLREIGLRGIFAGWGLSFMKDSMGSAVFFTTFEYVKAQGYINFVRWYYGGLSQEIVDLLAMKRPTDKDKMMKRSNQSKHDDKPTVIRPHYAIEPAFLLLAGIGASFGQQILLHPLNHIQTKHWDHLEDLDAKATRLRESNAANPEKPHRKWRMMRAYYRAYQETWAQLAAEAKAEGTSLTRWFYRGFWWNTIRQVPSTSAGLIIFELVRRKYGMGTEEIRITKDGYDILLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTZ1</accession>
    <name>A0ABR1UTZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660992.1">
        <property type="nucleotide sequence ID" value="XM_066818804.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051864"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="519" mass="57887" checksum="8375179324621236" modified="2025-10-08" version="1">MTLPQSQLIRILQTRFAGARSGWIRQGNTSALVSGRASDDEAPRHLLDGASSTALGANHAPEDPPDHPGPVNHPRALHNGTAGPSAFSGRAQGLLSPGSGADESPDRSPGAMGMTRNHRSLPHITRNYVSEPQYPITQVMPQPNVGKHAPRPSMSGEEAHLFRHYIQHIAICLDTCDPLRNFELVVPQRIGTYPILLKATFAIAARHLSRTSEYDPLASNRYHNQCLTQLIPMIDDAAGGLSDENLFAATIILRMLEEMDAITGNESHGHLLGIHAFVNIGDQYMVPGSLSAAAYWAGLRQEIYSAIISQSRVKINLDHFIVDRSLQPADDYTWSNRAVVNLADVLNYCFDAPPSPEQWAALDEHCRRWEELRPSSFEPFFYQERQIPDAFPQSWHHSSCHITGIQYHLLAQLFLAQFDPTIPRVGTKRTSAMKKVTQRIDELMRRLCGIGASNQWAPPAMFEASTGIAMFGDRFEERVDQEAMLDILRRTESDHARPTKAVQQQLTRAWGWMPSYEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVC3</accession>
    <name>A0ABR1UVC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_014978</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661480.1">
        <property type="nucleotide sequence ID" value="XM_066819292.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052352"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF93">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="24"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="293"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="345"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="421"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8062881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="463" mass="49930" checksum="06E0B8D4E1593D1C" modified="2025-10-08" version="1">MNRGLELAVAMWALTAFSLTLVVARLYTRRRIVKFVGIEDHMYAWTGVFLLCFTVFIQVAVQHGLGKSFWGLSIAESSDAIFWTYVANSFAITGNAMAKLSMGLFLLRVVQARWQRVVLWLAIAVTSGTSIALVVMLWNQTTPIRTSWDPLRTPGKWNIEIQPMSVMLGVWSSACDFLFAIFPWLFIKELRMPQREKVMLAGGMSLGVIAGACGIVRTVVLSKLDVYNYTCKHLGSRNRVPTLRQVADSYFPVNFVPYFAWAGAEIAVAMICIGIPTLRPLYLKTQQNLASAYARSQRRGRHGRRPSRHSQQLPPFTMVEGPLAEGEATTSRRCCSTTTPSSRRRCATAAKACSSTPPPPPRRGPARTRRRCGPTPADDAVGLDPDADGVGGGGGGAAAGVEAAAGLYARLARHEHDVYRGGGAAAAGGRAGPGEGVLPPPEPPIPTQQGRVDCAGRMAGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UW46</accession>
    <name>A0ABR1UW46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660869.1">
        <property type="nucleotide sequence ID" value="XM_066818681.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051741"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="19762" checksum="CA5421E95F87A2F9" modified="2025-10-08" version="1">MLGLLTIPPELQLMIQRYLLTRRDRLALSGTCQALNRMFGGKSFYEQDAAEERDFDEARLRLEDINRSHVHGELVFQEKDFTEDWSKAMHARFARAEAAATVLTADSSEEEKNAIEDEVNEIITFMKDCVGRWGPLMLCLTNPVLQGGDVKIWRQYPGAHSASRLPIKDRPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1E8</accession>
    <name>A0ABR1V1E8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dockerin type 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661762.1">
        <property type="nucleotide sequence ID" value="XM_066816070.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049130"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15892">
        <property type="entry name" value="BNR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="53822" checksum="2AFEB8D38C6EE3FE" modified="2025-10-08" version="1">MLLEPTVSVLGTDPSWRKHVLNGNAFQQDAIQSFNGWQYACFYSDSHGPEKSASSSNREPLYVHLSRRKLPLGKWETLVFHDYLQTTDDGHNTVQLGICPGDGTIHLSYDHHCDQLRYRHSTPGLATDPESFSWSARHFTPTLHHLPGLESSLPHAELLSNITYPRFGQLGADLWFSFRTGKAGLGDDHLYLYSASRSTYSPLCDVVADATAVTATTPFLKGIQNNPYIHGLDARDGTLYVTWVYRDFVWYAGWDDPADTQHKQQAGPNSAANKPGPVLRAWRNGAGDVVTDLGRGESITPSSPGVTAFRIPKGSGLTNQEAQAVDRDGGVHVLNRDCLSSSQTDDNGKKEVRWKHYYRNPTSKTWTSRPLPCGYVSGKRGRLAVSRDNDLYFILPGSSDDDGSGLNIWKAAKSDAYSTYALVWKSRSSSTGAPQHFPLTEPLVDTYRLDHDNVLSVFTRRYAAEEVAAAGDERRIDVVVLDFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1T9</accession>
    <name>A0ABR1V1T9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mov34/MPN/PAD-1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011892</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661899.1">
        <property type="nucleotide sequence ID" value="XM_066816207.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049267"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="8">
        <location>
            <begin position="35"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="334" mass="37270" checksum="E4F161D8EA85EE9E" modified="2025-10-08" version="1">MDRINRMLAGAGGMGGLGAAPGADNANLIDNSETVYISSLALLKMLRHGRAGVPMEVMGLMLGEFVDDFTVRVVDVFAMPQSGTGVSVEAVDPVFQQKMMDMLTQTGRPESVVGWYHSHPGFGCWLSSVDINTQQSFEQLTPRAVAVVVDPIQSVKGKVVIDAFRLINPQSLMLGQEPRQSTSNLGHLNKPSIQALIHGLNRHYYSIGINYRKTALEENMLMNLHKHVWTEALEMEDFRHEGERNKEHFQRLVTLADGYEKRVKEETELSKDQLKTRYVGKLDPKKHLEDVGQQLIEDNIVSVSRQMIDKEATMPKKDTVANGQSNGDHMDVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2H7</accession>
    <name>A0ABR1V2H7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 25 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662149.1">
        <property type="nucleotide sequence ID" value="XM_066816457.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049517"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="351" mass="38167" checksum="0538DE4ED10351AE" modified="2025-10-08" version="1">MPCGAGLGRSFIARIALALVILTVTLCFLWYRDLVSPPSRFDAILALSKGGGQSWRVQGLQAAAKLSGLNISVPPQPTWLPEMVEAFAALSPEGVPKPEPGSAAAWLAHIDLLKYVLQSQLNSALIVEDDVDWDVHIKDQMSNIAEAVRQQTHAPHEQTNPYGSKWDILWIGHCGDTPMPNETVSLFPDPTVLEHKRYVGFAGTKSYLQEHIPEGQRAVYRSQGAVCSYAYAVHKSGVRKVLDFVSTGLGQAYDTKLFYGCRSGMLNCVAVTPEVMVHFRPDSKFGQTSEAASDDGSIGGQEGGGRPEKVATSVAEKITGTTNNIRQSARCMSLWKKACIGGRNVIRGRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2M3</accession>
    <name>A0ABR1V2M3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662196.1">
        <property type="nucleotide sequence ID" value="XM_066816504.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049564"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39401">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39401:SF1">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="145" mass="16651" checksum="8BC25D8F3F766B8F" modified="2025-10-08" version="1">MAAPSGYTPEFPSTFSPTEKLRDFIPSFFQVSDDGSRNEEWVGCFCSDATLVMGGDEAQGTERIRQLRSRMWDKVASRKHSVHHFSEATGREPHEKGERNFMLKGEVEYQLKTGETKTVPWTAHAKVKEDGDRIRFVYYKVEIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V396</accession>
    <name>A0ABR1V396_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Malate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662410.1">
        <property type="nucleotide sequence ID" value="XM_066816718.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049778"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF1">
        <property type="entry name" value="CONSERVED FUNGAL PROTEIN (AFU_ORTHOLOGUE AFUA_1G14230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045279868" description="Malate dehydrogenase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="29438" checksum="6B31E7A00381F2EF" modified="2025-10-08" version="1">MRCSILFTSALSASTVIAVPTWPAFSKSVPMPAQLETMSSWFNALAKVVQDGRASPRNPVCDLSQVKLPESALPPPSAGLYLKHVAVGRGTQNYTCDTSNPSSAPVLFGAVATLFNASCIASSYPDVLQLVPKTALQFDLPAAAGGPPRPAGGPGGPGGPGGPAEKMGPIDYVLSGHHFFTDVTTPYFNLDTTPGSQYGTIPCAKLNQTAAPADAPKGQQGEAAVAWLKLRSKDGATGDLQEVYRVGTAGGSSPATCEGMPSSFEVQYSAEYWFYAGSKPKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V449</accession>
    <name>A0ABR1V449_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Impact N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012718</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662724.1">
        <property type="nucleotide sequence ID" value="XM_066817032.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050092"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF4">
        <property type="entry name" value="IMPACT N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Impact N-terminal" evidence="3">
        <location>
            <begin position="279"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="546" mass="59205" checksum="1484FC0BC3AAA65E" modified="2025-10-08" version="1">MASQQDLQELLRLMTVAKVPIKDAMMRVKALQAQNLRSIKDIAEATLPTIESAIPDPKAARQLHNACKARLKNPAVSAGSKRAGAELLAQTIDGANKRTKADPDASYQDGPTPLSPADFEASLALPVETDEHAISATTLLTNRAPLVLAFAAELLRYTMPEQPPSSRLSLAQAVVSANSRGKAVSIGIEKGPSADQEGWGHGQPRVQIMGREVTVLKRGGYEWKGDGEAGSEVKTENPPSIASLATAVAGESQSSGPGKNITVDQISQTWSASSPIMSRDSTFIVRATKLATLSQRQASLQTLFTAIPNLRSADHNAWAYRVKKPDMFGSHVIREDSFDDGEGGSGDFMLKIMRETNTIDTLVVMTRWYGGTMLGPDRWRIIRTCLKEALAERLRATGEQASISGEAVWGLDLEAMRSKTNTATSSTRSYSASVVGMPVHRPESARAYLLKSFAQRVEGDEENPTPKKKTAKALEAEKEENVSRLLGAIRMLYDSWAGHLSASELDRRAWGWYMSVRPEVESGPSGWGAKGNLKLANILALRRKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4A9</accession>
    <name>A0ABR1V4A9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">General transcription factor TFIIB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012776</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662782.1">
        <property type="nucleotide sequence ID" value="XM_066817090.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050150"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF13">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="Zn_Ribbon_TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="7">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="219"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="365" mass="40343" checksum="FE98F83A007DA2E4" modified="2025-10-08" version="1">MDYTMDTHNPASSMPAQSSFMRENVLKCPECPPEGGYEIVDDFGTDDWICTGCGMVLDRVIDDGADWRTFANDDGTDGPDRSRVGGHAGDELATFIGGNLKTSSLARAEKRGKEANKNSMAVQRGNARIDEFCEQHGLSRDIKDQAYNIYKLTQDAHQFRGQVKQEAMLGPIIFIACRTVKQPRTFNEVQAMTQQSKKVMYATVNKLVAFLRKKEPQKAKKASSASTSAAVEEGPSPIPDTTASDPRPDTKVERIKVPMARFVANMNFRNAFVVETIATRMAEKAETISTPFDGRTPTLLAAAYICFASWLVGEPRKMKDIALGCKVGQGTLKTILKSFVQMQDQLVDKSWKAVDLSRVKDLMTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V501</accession>
    <name>A0ABR1V501_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013017</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663023.1">
        <property type="nucleotide sequence ID" value="XM_066817331.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050391"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF22">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="39647" checksum="BEE53CCDF6B6AEBF" modified="2025-10-08" version="1">MASVSKSIEAVKKLSSVSVHLPESQDYDELTSSYFSELERELRPACFLTPRSAQEVADILKAIQPFAGPSEVAICGSASRQHREWPMLATASPFICETSGDRDRQGKNSRLGGLSYFSYARGFVSDDVVNYEVVLANGDIVNANAETNRDLWIALKGGGNNFGIVTRFELNVFERGPMWGGKSLVEYHHQPEPDTSAHICLSLGYAAALGDIVCINDVFCSEPAKPKALKPFTDIQPQIDQMNTLSVNSLRESSRMKNSRVRLPTVSMMEQSMARGGNSQGLDPSQGPLVVVMFYTSWDQPEDDEVVFSVSKEALERIGIEGKSRHMSAQYRYLNYAFPYQHPIGSYGPESNARLHAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V531</accession>
    <name>A0ABR1V531_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663053.1">
        <property type="nucleotide sequence ID" value="XM_066817361.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050421"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045201060" description="SnoaL-like domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="61"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="23405" checksum="A346F94C493732AF" modified="2025-10-08" version="1">MLSLAASVLFFLALLVIPAQSLGPELFGSPPPSQPCPNMAPGPVPISELVQTLQPLRAVSDLAAESTIRNTLALYPLAIDTRTFSALDRIFSVDARANYSYPLGVMEGREAIKTSLQQALETTWKGTQHMYGTQIIQVCSPTSAISVTYYTASHFLVAGTGPEALTGPQSVVYAYGQYQDTWERQGGEDGWRITNRNLVYLGPLIADAPLGNGSNPEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5G8</accession>
    <name>A0ABR1V5G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_013179</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663185.1">
        <property type="nucleotide sequence ID" value="XM_066817493.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050553"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039745">
        <property type="entry name" value="Vps54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012501">
        <property type="entry name" value="Vps54_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019515">
        <property type="entry name" value="VPS54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07928">
        <property type="entry name" value="Vps54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10475">
        <property type="entry name" value="Vps54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 N-terminal" evidence="11">
        <location>
            <begin position="271"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 C-terminal" evidence="10">
        <location>
            <begin position="804"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="133"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="529"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="773"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1056"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="302"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1081"/>
            <end position="1091"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8066432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1102" mass="121274" checksum="908DDF907B177C29" modified="2025-10-08" version="1">MYSNQSVRLSVDSLSSPQSPQNSRGEFPFHRQGSVTSHATARRGSTASSIHSIGGHLDTSNSWAQGIQEIGQNVRTGLLPHTTAPASSAHKPPTARDIPPVTLTNIEKIDVAEFKPYLSQVGALYEQLRRVKESEDNGADQVFRRSSKPDTVPDLDDGHLRPGSSGGRPSSSRKASTSSFGSASPLESPQIRRRSSAGFNRKAAHGPPPLNTIPNVYFDEDFHLENPRTFDVVSERSEVVKPQPGSSEEKNVTNGTVAPRKSLATNAILQEKLSWYMDTIEMHLINSISTASTTFFTALGSLRELHSEAAESVDRIRTLRKELDALDQEIATTGLDIVQKRRRKENLQQLDDAVHQLREIAESLSECESQVETGDIEKALTNIEALERLVAGRKRLHGKDNGRQIRDLRDAVALQGVNSDISTLRLRIGKGYETRFVDVLLEDLRRHVDTVSTQDVLLRWTSATMRSRGGHAKDATAFPPAYLSSTGGLRAQLMPVVTGLHQAKHIMMAISSYRELVLREIRKLIQRPLPSSDDDDNATIMSASTRSGRKLTQGEKSSILARNLRALEPEDAEALFTKIYIGVTETLRRLTTQVKVLFDVASSIGESPDVTSGMRSPPLGGLKSPPLNSANQDIQEDIHLTLDMANLLGQTADLAQDKITKVLRVRSEQSTRLPLDLFLRYFTLNLYFTNECESISGRSGSSLKTVVNGHIKDFIDQHGDVEKQKLAQEMESDQWAAKDFTDENKLLLNRVIDSSTRDDVSWSEGSKIWIPYSNTQPVSNGRPRAESNGTGPRDKTRSAVIDSESFILPRSAILCLEGMSHFMQLIAGIPSMSTDIATSLISYLQVFNSRCTQLILGAGATRSAGLKNITTRHLALAAQALAFISTLIPHVREFVRRLAGTGANVNNTSLAALMGEFDKVKRLYQEHQNNIYDKLVEIMSGRAAAHTKTMKGLDWDRPAREGEASVDVFMETLVKETVTLHRVLTKHLPEGTVHLIMAPVFDSYKTQFGNALQGLEVKEEIGAKRMEDDIGYLINRLGKVEGFANTGEHLLNIVKTKMPDKPPPVPEKNGAVSKPNSPAPKEAEKPEEQKSSEAAGKNGGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5M3</accession>
    <name>A0ABR1V5M3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012333</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662339.1">
        <property type="nucleotide sequence ID" value="XM_066816647.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049707"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_uL14_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_uL14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13238" checksum="CE4A85E21C86B369" modified="2025-10-08" version="1">MLNCIDNSGAAIVECALVVGRKRHASIGDRIVAIVQKQRGASDAGMGSASAANKVKRGDIRHAIVVRTRKQVQRPDGSVVKFDDNACVLISKAGDPIGTRVNGVVGAELRRKKWSKILSMAPAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6D1</accession>
    <name>A0ABR1V6D1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663514.1">
        <property type="nucleotide sequence ID" value="XM_066817822.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050882"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="48610" checksum="0A7A6A7A90364388" modified="2025-10-08" version="1">MSTKATTPISDTPPPIQQPPRTPRYLQRRPPSLSCASNPPPPPSVNHHQPQPQPPPSSARSSRNRRHSLPFFSYPLVSQPNVSSTSLVPSTAEGKPIPLDDSTAADRTTALRELNRSQPSSRHRYTKSTGAPSTATRTTTGTYSQPVIVRTYSGPPPSSIASRPASRRIPLSSNATSLQTSSWRPGRNGMVLNMARHRGTKKGQSRNDVKLPPLEAFSFKNIMADIQQDIGADLDRIAEICARSKYSLSNQYEVHVVPHGSGTGFLSSASASSARAQAPTIMSSSRSSEEDKSKKKSAQELTDDVRGRASGKRKDGSASSSHSGEAPSSPGKSERKSVSRRKSNSFATAVIDSTRQVQGSGRRPGRRGLRLSANRPNPRHPIAISKYGRRRNQGRTVIQPRHLPNRREPCCLPPWPQRILPLLKSRGNNNMESWLASATGYPGEGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V759</accession>
    <name>A0ABR1V759_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquitin-conjugating enzyme E2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013783</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663789.1">
        <property type="nucleotide sequence ID" value="XM_066818097.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051157"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="72"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="232" mass="25974" checksum="D2E8DBF7EA7F55D5" modified="2025-10-08" version="1">MASSSSESANSSKLASDAATQPAMSNENSKREPSKKVSLGEDDWGLQLRPIRLLDAQANTQEYVRKPARLGVNWKRVRNETKFLNEKSMSMRILKAEASNPTATAIVTFEGPPQSPYRTGIFQLRVVYGPNYPRVPMEITFLTKIYHPNIDHAGKICLGMLGKDWSAMWSTREVVLCTMALLSDPYPEDAFVPEVASLYLRDRDLYEKNAATYTEKYATLGAALERLLMASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V791</accession>
    <name>A0ABR1V791_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycoside hydrolase family 78 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012676</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662682.1">
        <property type="nucleotide sequence ID" value="XM_066816990.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050050"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035398">
        <property type="entry name" value="Bac_rhamnosid_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF5">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17390">
        <property type="entry name" value="Bac_rhamnosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046694825" description="Glycoside hydrolase family 78 protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="2">
        <location>
            <begin position="256"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase C-terminal" evidence="3">
        <location>
            <begin position="592"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="700" mass="75541" checksum="BB8B625A694952BE" modified="2025-10-08" version="1">MARLSLSSVATLFPWLLVIGAQPGYAQTCWRHTQCSSILTAAFPGTWESNIFAPSSRIVAPSVLLGTDGNQISTFPSQATLDKDKKAIVFDFGFEVGGVVTIDYTVSSTPAGGTIGLAFSEAKNWIGPVSDSSTGDYDNPDIAIYADNRGTGDFSYVMPDENLRGGFRYMTVFATANMNVKIHNVSVELAFQPTWANLRAYQGYFHSSDDLLNKIWYSGAYTLQTNSIHPATGRTWPAPSNGTWLENGLLGPGNTILTDGAKRDRTVWPGDMGVAVPAAFYSTGDIESTRNALQSLYELQDSSTGELPFSGKPLRATGSTTYHLWTMLGTYNYVFFSDDTDFLLQHWDGYKAAMTWAQQHVDSSGLLYSASVDADWGRFGADGTLTSIQALFYHTLNTGAILAEWAGDANGLGDGWLKQAADIKSMTSKRNWDSSAGAFFDSADRKSIHPQDGNSLAVLFGVVNASSNEASGISNYLKGKWTPIGAGCEELPGEVSPFISSFEIQAHLLAGQTQRALDLIRTSWGWYLNNPLGTQSTMIEGYLTNGTFGYRWNAGYQNDFSYTSHSHGWATGPVTALTEHILGLSVTGRGGSAWRLAPQVGDLSYAEGGFVTKRGRYSASWSREDDGAIKVEYAVPEGTQGEVSLPLGANVDPAKVTVNGKPLRGGSKRTAAAWRAEEAPGGRRVLTMRSPGGKHSFSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V809</accession>
    <name>A0ABR1V809_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664070.1">
        <property type="nucleotide sequence ID" value="XM_066818378.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051438"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050583">
        <property type="entry name" value="Mycobacterial_A85_antigen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48098">
        <property type="entry name" value="ENTEROCHELIN ESTERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48098:SF3">
        <property type="entry name" value="IRON(III) ENTEROBACTIN ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046341741" evidence="2">
        <location>
            <begin position="24"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="708" mass="76634" checksum="E2AB211C3EA82AE5" modified="2025-10-08" version="1">MDFFLRLNRASVLLASLLATANSLRVQISLQNGTDDDDLLSGKIDGRVVLMFAPNGTDPLADIEVTSTPNYMFGKNVFGFDAADTIAFVGGSGDVNATGTGGVYGFPLVSMDELPAGAYRVQAFLNPYDRAERSDGSVVHLKFPCGDGALQVNGVGSLVTPPVDVEVVDGGRNSTNLQTISLAFDSVTPVEAFTGREVGRCEQGNYADTELLKYVKIRSAKLSEFWGRDMYVGATVLLPAGYDANDETTRYPVLYSQGHWPGGKGPFSYPTATFSKAWDAGMIPGDNKTAARPAPKLILVRFRHEAPFYDDSYGVNTANLGPYGDALNDELIPYLDSLFYTIAAPYARIQEGGSTGGWISAASVIFRPDLFGACFSSYPDSLTFAKHQDISLYRNANAYRNADDGSRIGSIRAFDSPGNNTETILATVEQENHWELVFGTASRSSLQWDAWNAVYPDAVAYWKELGMDMAEYIAGNWGFNTNSNFIKSSSKKNLGETLRDRIHVYVGTHDDYYLNEGVAAFAQRVNAPQLGGPDWANITITPGATHGGNYQRREIWNYLELVADWVRDHGPEGATPLSAEAVSPNNRGNRFEDIVRIGGRAAALARQADPTVEVVAGGSAKCGGLPRITGTVGRWDPGVKLEAQWVVDGEASGAAFGAKQGDVVRYASVGSEQAKKGFGVSLRVKGTKRNYEDETRESAVVEAMPRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V817</accession>
    <name>A0ABR1V817_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aquaporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012870</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662876.1">
        <property type="nucleotide sequence ID" value="XM_066817184.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050244"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="34855" checksum="76635C54C52DB877" modified="2025-10-08" version="1">MNVDHPGRRIRMPWEPRTEVRVRSAASGSLDDGSTVASHPRHIPILSRCPKKVKNHLVAMLSEFVGTFMFLLFAFGGTNAVNTAPTKGEPLNANPAKLLYISLCFGMSLMVNAWVFFRISGGLFNPAVTLGMMLVGALNYIRGSLIIISQILGGIAASGVIYGLLPGPLNIRTELGGGTTVVQGLFIEMFLTAELVFAIFMLAAEKHKATYIAPVGIGISLFIAELLWVFTLYFYLSIPLILVISDLKLTNVVIRGVYYTGGSVNPARSFGPCVVLGSFSHYHWIYWVGPILGSLLASAFYILVKALEYETVNPDQDAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V852</accession>
    <name>A0ABR1V852_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spherulation-specific family 4-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662997.1">
        <property type="nucleotide sequence ID" value="XM_066817305.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050365"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="186" mass="20897" checksum="0A1622B2F4018AD9" modified="2025-10-08" version="1">MKLALSSAPTQRRHDIRHMCRGGGRCPLPTGHSLLRRDQPQQRTKEHLGLQRERHKQLHAQGQQLHPAQLRQEQVDQGGPAEPGWAGWVSEAGWASLCSNILIHGIWSDETVVEKGNETAFRQPTDHVRQGFAAKGTNRGQFDIVMNPAEDHEQALSDTTDAVVTRETYWATTVGGECPWPYAYYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8J2</accession>
    <name>A0ABR1V8J2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663374.1">
        <property type="nucleotide sequence ID" value="XM_066817682.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050742"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF5">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE ABHD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="63"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="348" mass="37563" checksum="1FF08FAF2723418C" modified="2025-10-08" version="1">MAAQQYHAAEVGARKTDNDGKPDWVPGEAPLEGVMRGSCGMELFLSTNGPPRIPGHPVVIFEAGVGACSSSWGPVRRLLDPRIRSYCYDRTGYGRSPSAPVAGSPRTAGVLAEELLDVLSSAGVRPPYILVAHSFGALVAREVMAALEPDDVVGLVLVDANQERAYKAIEEPLKPLAALAGPRGLALLDQSGLLAGGDHYTSDELQRLTVDAEREAKENTSALETACLEASSDALAQKSQLETMALGVRPVTVIRGDTKRDYRRVIAATRQRSDLDAEASRVLEKLHNFVEKEFDVRDNALQREQMRLSANSRFVQALESGHAVIATEPHLVADEVSSVWESCLVSWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGU8</accession>
    <name>A0ABR1VGU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Sister chromatid cohesion protein eso1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_010668</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664273.1">
        <property type="nucleotide sequence ID" value="XM_066814983.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048043"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052230">
        <property type="entry name" value="DNA_polymerase_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041298">
        <property type="entry name" value="UBZ3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873:SF1">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21704">
        <property type="entry name" value="POLH-Rev1_HhH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18439">
        <property type="entry name" value="zf_UBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036603">
        <property type="entry name" value="DPol_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51907">
        <property type="entry name" value="ZF_UBZ3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UmuC" evidence="12">
        <location>
            <begin position="43"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="UBZ3-type" evidence="13">
        <location>
            <begin position="550"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="375"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="465"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="580"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="471"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="535"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="602"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="616"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8070465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="626" mass="68884" checksum="77E5976AD251DDA3" modified="2025-10-08" version="1">MPSSPIFQGSSPGYGTGRRKSQFTYRQLGLLTSYSTSSPLRVISHIDLDAFYAQCEMVRLGTPEDQPLAVQQWQGLIAVNYPARKFGIGRHSTVTDAKKMCPQLIAQHVATWKEGDEKWAYHEDAASHIGTHKVSLDPYRLQSRRILALIKESLPANMQKVEKASIDEVFVDLSAQIHSILLQRFPELANPPPYDDPTEKLPLPPISALDWQADALVDLDDAEAEADDPDWDDVAILIGSEIVRDIRAEVRRKIGYTCSAGIASNKMLSKLGSGHKKPNQQTVIRNRAVQHFLSDMKVTKIRNLGGKLGEQVTSVFETDSIKVLLAIPVEQMKAKLGEDTGIWLYNTIRGIDTSEMAQDLCCRYLFAIGGGRGPGEQAAAQDNQPSSPPRGQTRSRQNAIPQGKILDETTLFELAKNLMNQIALEGRIWPCANLSLSVAGFEDGVTGNMGIGGFLVKGEEAKSLMSSSREASVDPHSEARPEKRRRTDNPGIQRFLARASSSSDVNDGGTEEAREHQSHQTVANQPPPEHDASLQVEQDASTTETKTRQLPITDYTCSRCHARLGNAEAHQSHLDWHFAKDLQEEERGSSTLANRPAGPRNQKPSASTSRQATRGSGKKQSKLNFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGX4</accession>
    <name>A0ABR1VGX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sterol 24-C-methyltransferase</fullName>
            <ecNumber evidence="11">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Delta(24)-sterol C-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_010689</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the transfer of methyl groups from S-adenosyl-methionine to the C-24 of sterols.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Steroid metabolism; ergosterol biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10 11">Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664294.1">
        <property type="nucleotide sequence ID" value="XM_066815004.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048064"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030384">
        <property type="entry name" value="MeTrfase_SMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013705">
        <property type="entry name" value="Sterol_MeTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF1">
        <property type="entry name" value="HYPOTHETICAL LOC100005854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08498">
        <property type="entry name" value="Sterol_MT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51685">
        <property type="entry name" value="SAM_MT_ERG6_SMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 10 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 11" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="5 11" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase Erg6/SMT-type" evidence="12">
        <location>
            <begin position="85"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8070486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="387" mass="43326" checksum="AD3AAED1767E75D9" modified="2025-10-08" version="1">MASKSKILEKQDRERDAAFNTAMHGEASGADGGFRAMLRKGGGTAAQRAATEEYFKHWDNQAAKDETEETRAKRTAEYATLTRHYYNLATDLYEYGWGQSFHFCRYSIGESFYQAIARHEHYLAHQIGIKEGMKVLDVGCGVGGPAREIAKFTGAHITGLNNNDYQIQRATAYAKKEGLSHQLAFVKGDFMQMDFPDNSFDAVYAIEATVHAPELSGVYSEIFRVLKPGGVFGVYEWLMTDDYDNDNLHHREIRLGIEQGDGISNMVKVSEGLEAMKIAGFTMMHHEDLADRPDPMPWYWPLAGQWKYMQSIYDIPTIARMTWWGRGLAHRFAGMLEMLRVAPAGTRKTADSLAVAADCLVAGGREHLFTPMYLMVGKKPADTNGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHV1</accession>
    <name>A0ABR1VHV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664602.1">
        <property type="nucleotide sequence ID" value="XM_066815312.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048372"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="49309" checksum="4B7FB69D76033667" modified="2025-10-08" version="1">MKGWLPSAALVTALGTLVEHIVPPSLRSLLYVSNWEGDHFSLNGPSDSGVQAALDLTDAFLKIRVIDGVVRGNRQLHQIRQCAWSILTVNVERNHWVTVIIALTGQDDEDNDNKDYYTRVERISVIEGIDPGPMGDYKVNVYSCVEGLLRFAGLQFTDSEAEPLPENSWRQPIWVPTQNNAYSCGVRAYANIKTMLRRLATAWEAMAPDEGLKSLPPSATAAENRFLWDPMPGWFHYELERWEMVGSNAATIVRACDYQARIAVEVVKRARGPKDDPKKGETSEAKKAINVPNDDDDPFDDDDGMPFYEGWSDKMKQEVRRQYTGTGTPEREKKTPETDTSPEEDTPSPPPTLTERQVAIKEWAGVSVWLNPSPSVRRGGKKRPREDDVVDLTGNNDGGAIPISFNRTRADTGHYTNPFASRQAAAKSVMIRRGSRRPRGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI38</accession>
    <name>A0ABR1VI38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Biogenesis of lysosome-related organelles complex 1 subunit CNL1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">CNO-like protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_011103</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BLOC1S4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664708.1">
        <property type="nucleotide sequence ID" value="XM_066815418.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048478"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034455">
        <property type="entry name" value="CNL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39145">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT CNL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39145:SF1">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT CNL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="139"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8070900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="180" mass="20837" checksum="CA77CAD9A6CE86FE" modified="2025-10-08" version="1">MPSTEANTVPDAQLGLTEDEIQLLRYHQTQANSSSSRAASRASSQGRLLLDSSSLAALSRHLDRLMVQIQQRIEYLSEQSSMVTMQQYDHAGNLIDTADSEIARFHEIMRQLDELELDFDRIRHIRDIVRGYRQRVEELDRELEHSTSSRRDREGHSSHRHGHGHSHRHEGSSSTRRHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIT3</accession>
    <name>A0ABR1VIT3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD-dependent glucose-6-phosphate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011326</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664931.1">
        <property type="nucleotide sequence ID" value="XM_066815641.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048701"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103:SF5">
        <property type="entry name" value="4-EPIMERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="4">
        <location>
            <begin position="3"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="259" mass="28454" checksum="2F91873F22992D46" modified="2025-10-08" version="1">MKIAITGARGTVGREVVKQCAKEGHSTVQINRTPQDHDHGTPNTEMRTADAAADYDATLAAFAGCDAVIHLAAIPDPKGKPDSHVHNNNVCAAFNGLRAAAAHGIRRFCYASSVNAIGLAYSNQPLRFAYFPIDEEPYPVRPTDAYALAKTEAEAAARAFPDWFPGMKVACLRIHEVAPRRDVLQEHDEDWVDAGVKQLWGWIFNIVAPDTTQGGTPSADLAKKYYPDAEIRADMSTNRSFWSTDKAEKILGWVHHEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJR1</accession>
    <name>A0ABR1VJR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWR1-complex protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011325</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SWC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664930.1">
        <property type="nucleotide sequence ID" value="XM_066815640.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048700"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032563">
        <property type="entry name" value="DAMP1_SANT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027109">
        <property type="entry name" value="Swc4/Dmap1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855:SF10">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16282">
        <property type="entry name" value="SANT_DAMP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="DAMP1 SANT/Myb-like" evidence="9">
        <location>
            <begin position="136"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="94"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="339"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="514"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="574"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8071122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="644" mass="72109" checksum="5F4C8C50B999D149" modified="2025-10-08" version="1">MTSHDVREMLNLPNEGGGSRPAKKQKTSIARQNLKGLAREVQNLGGDNPIAIVPEISSFKKRRFGSRKPAARWEMRPFRNSAREDESLILRHWRRKTDVQPPTAPQPDQQPNGQPDEDKMDADNGESKPEEMEDSSFAKFNVKVDVPQYSEDQYNSTLANKDWTKDETDYLMEAVRDYDLRWPIIWDRYDYQSKDGDASTDSNTAVVQARKPRTLEDLKARYYEVAAKMMAVQRPVQYMNQAEYNLHEIMTSFKPEDETRRKKFAEAQMGRSKEEAREEESLLLEVRRILARTEKFNQERRELYNRLDYPTTETTQDLSTFKTSNGLHTLLQNLMTADKSKKRKSLMGTADGQSTPASAGPSAQPGSTPLAEQRRESIAASASGHGHGRHDSTASTTDARPEKPTKKGAQPPERRKLTEQEELTYGVSTHDRLPSGPTFRYDRINKILTTKSNAQHARITNTLNELDVPARLTMPTKAVVDQMEHLLINIQTLLDLKKLSDKFDAEIKLEKAKKAEKDKAAGIVPQPAAAESTKGNSNGETAKVNGAAKKDGKKAGGDVATSSTEKPAAGEGANGDKDAPKEGASKHRLKSLLATVRGWTMKRPLPKKPKIKMLRMGSSKRLAPGKKRMRDLAAVADRSALQAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJX3</accession>
    <name>A0ABR1VJX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aspartic peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010723</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664328.1">
        <property type="nucleotide sequence ID" value="XM_066815038.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048098"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="3">
        <location>
            <begin position="72"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="600"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="652"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="606"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="714"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="728" mass="77924" checksum="B90B34672A5C17EB" modified="2025-10-08" version="1">MCQTRDAKIAGRNHSFAASEARPRAQELRTLHGNEPPPSTPRLDDHNRRANAATGNTTNELRIRLAGPNLTYTAEFGIGTPQQKLELGITTTLSVVPLHDDSLLPPCEGDGCPYGTYDPTVSSSSEGKEKYTMQDPKGAHGQFFIDTWQVGNARVANVSFSANAGDTREHAFVGLGGVMKTENTSRPSLTAAFVAAGLTTTSAYSVWLGERAPTAGRAGSLVFGGIDTQKFQGTLTRLKTYPLQLDETKDGRLGVQLSSIMAVSITGTDMLACGTQPLLVEIVMGASQIRLPGDLVEAIYKEVGATPDTSRDGAATIPCHMGNSPAYFSFVFSAADGATPSTGAMVNVSMSSLVLPNNLDTNRVSKDMFNDPQSPTYLAFDQENGEIGIAQSNPTPSGSYMIPFPSKGALIPLATPASQTPGPFPSSVVTSSIAPLPTYSAADGFQNYETARPPPAVNSSTEASTSPNQELVIGLGAGLPCGAVAVFTGFMAYWRIKLRRPIPILSRFSKRRWINPYATELEVKHPQPDAAEAVGFPWTFDRPVGWTELDAPAKPVELEGDYSFYQHPIPCRHDSMSSTAVDTEEARSAVAARESLIVPGGIPVATSPNDGGTTNKRGSDSYIDTTPKSPLRMSYVPGPDVIDVGVLADHPENFKDTRPNLPEESQMRGQVATDYDNESSIRDESQVEEASVGEYVEIARRTPYYTMNPSRDSPQPPLTPPPPGSDWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VME6</accession>
    <name>A0ABR1VME6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664821.1">
        <property type="nucleotide sequence ID" value="XM_066815531.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048591"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="89" mass="9594" checksum="36AE94F24924F358" modified="2025-10-08" version="1">MALHAASGTPETDDDRGVSNSESEVFPTTAFPPPLRASSILTLVRLSNSAVPAIILYRLNPGPRASPVDWAMYGNGAGWQWERILLFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTC7</accession>
    <name>A0ABR1VTC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Insecticidal crystal toxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665423.1">
        <property type="nucleotide sequence ID" value="XM_066813461.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046521"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020915">
        <property type="entry name" value="UPF0311"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315:SF1">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11578">
        <property type="entry name" value="DUF3237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="695" mass="76441" checksum="73DAA5540BF0E3CE" modified="2025-10-08" version="1">MTSNPNYFLMGAIRRQWMQGELPPLLPTGPPNEDADWDSSVVVHGDWMRAPAERRHSGWNAVEQSWSNVDGASTAREETPVQSQTPTAAESNNPGPSADSLGRLQPTLSLPAPELELDFRMVLELSEATATMAVGDNFKKYTTFTDGVWSGRIGNGDQDAMEMTLGSSLATQVESKYRLKTGDEPPAVIDCRTRGFLTAPAPVMNDLRDGEKTRPIDPRRYCYRVFITMRTADARYAAKVNTGMWVGTCLWDVAKVVYEKAIVSKFNVVRTSLIGNKTTPLQVGNGDFAFNVDNTGMQTFLPFNTLSTWAWHNDSLPTNGETVDDYLGVPMLTHARNVSYDIPDPDLPEISQWLIGNPNRINLGRIGLKYKGQTLSASDISEPRQELSLWTGCITSKFQVDGAPVEVVTQGDLETDAVAFEIESDLVASGELEVELDFPYPPIHSAEYKYEVFVGTYDFPLNHTTELVRACNESNNDNVAHIYHEMQETEYFVNLRWDAAETSSSPPTLRRNEPPGSSSKTAHRYTLSPGVTGDNPSSKFSFTAHFAPSKETTALPAEIRARSSATWSEYWREGGFVDVLTGSTNPNASELQRRIIQSQYHVRVNGASTHHSQPPQESGLVNNGWYGKFHMEMVVWHGAHWATWGRQELFDGIFPGGVREVLGVVGGAGAGDGVEGGEVAEDDGGGDGEERAPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU87</accession>
    <name>A0ABR1VU87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rhamnogalacturonan endolyase</fullName>
            <ecNumber evidence="4">4.2.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_009483</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1-&gt;4)-alpha-D-galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non-reducing end.</text>
            <dbReference type="EC" id="4.2.2.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide lyase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.23" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665760.1">
        <property type="nucleotide sequence ID" value="XM_066813798.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046858"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10317">
        <property type="entry name" value="RGL4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10316">
        <property type="entry name" value="RGL4_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1120">
        <property type="entry name" value="Carboxypeptidase-like, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029413">
        <property type="entry name" value="RG-lyase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029411">
        <property type="entry name" value="RG-lyase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016590">
        <property type="entry name" value="Rhamnogalacturonase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015364">
        <property type="entry name" value="RhgB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36574">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36574:SF1">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14683">
        <property type="entry name" value="CBM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14686">
        <property type="entry name" value="fn3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09284">
        <property type="entry name" value="RhgB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046505207" description="rhamnogalacturonan endolyase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase B N-terminal" evidence="13">
        <location>
            <begin position="21"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase" evidence="15">
        <location>
            <begin position="282"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase" evidence="14">
        <location>
            <begin position="370"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8074820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="543" mass="59293" checksum="4754DC5C18E24498" modified="2025-10-08" version="1">MLLLALFYSLLVWPAAVLAGFGWSDDGANYVIDSGADLVIKVSKCCGDIVSMQFKGVEYQGYGGKNTQVEIGLGPSDMTIEQINPVIKVSVTHGTLKHYLVFRYKNNNVYIFTNKKDASVTVSRYIVRFPANIFPHSPDDADYYDDGSEWIEASDVMKDSRGFTESKHYAGNTYGRTIDYDYVGKSNGNAGMWMVRNNHEKASGGPFFRSLVRRGSFTGEDLYEIYHYNMGHTDPERFGLQGPTVLAFTNGEPPSANLFARRADWGWFDNLGIEGWVPQSGRGHISGIGLANMKEGHAYVVGLSNPDAQYWATAGGNGAWSITGVLPGTYTLTVYKSELEVHTSSVTVEAGKGAAVHTITCADPADVPALWRIGEWDGTPRGFLNFGDTPMKPTYMHPADSRLAPWDASNYIVGTSTASIFPGYMWVDVNNDHVVYFRLTAEQIASGHQLRIGITEAYIGGRPQVRVNGWTSRVPPATGQGGTRSLTVGTYRGNNAMLTYDVPASAWVQNPSEWQVLTISVVSGSRGSGFLSAGVSFDCLDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUJ3</accession>
    <name>A0ABR1VUJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1348-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009584</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665861.1">
        <property type="nucleotide sequence ID" value="XM_066813899.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046959"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009783">
        <property type="entry name" value="DUF1348"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31757">
        <property type="entry name" value="SLL0781 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31757:SF0">
        <property type="entry name" value="SLL0781 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07080">
        <property type="entry name" value="DUF1348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="19158" checksum="AFC7D2691B8C61D7" modified="2025-10-08" version="1">MAAEKQGGRPPYPPFTAETAQVKVKAAQDAWNTRDPQKVKLAYTEDSIWRNRDQFLVGRDAIAEFLTKKWAKENGYRLRKELFAFTDDKIAVQFWYEWFEEGEEGGKRQWWRTYGLEDWTFAEDGLMRKRQMSGNDVRIAEEERWFGDGVDVNTVPIAEKHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWP4</accession>
    <name>A0ABR1VWP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010316</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666593.1">
        <property type="nucleotide sequence ID" value="XM_066814631.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047691"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF5">
        <property type="entry name" value="OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="9"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="346" mass="37157" checksum="DFEAA433ADE6EAD5" modified="2025-10-08" version="1">MKECIILKGPTVKIVDSPIPEAKRPNDVVIKVVVSGSNPKDWKCAEWMDVEVNQGDDIAGVVHEVGSDVTEFKKGDRVAAFHEMLAPGGSYAEYAVAHQHTTFHIPASTTFEAAAATPLAAMTSAVGLYLRLQLPQPWTPATAPIPLVIYGAASSVGAYAIQLARRSNIHPLICVAGASTAHVESLIDRGRGDTIVDYREGDEAVQAGIRKAVPANTKLLHAFDAVSEHNSYQNLGQVLSVPEGGSTNEKARLTLVLPGKVYEGIPAHVEQSTTMVGDVHGDHQDFGHVYFRYLARGLLEGWFKPQPQEVIPGGLGGVQKGLENLRDGKARGVKYVFRIAETEGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX19</accession>
    <name>A0ABR1VX19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010484</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666761.1">
        <property type="nucleotide sequence ID" value="XM_066814799.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047859"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF3">
        <property type="entry name" value="CHAIN DEHYDROGENASE (ATSC), PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="29942" checksum="1E2182E64FE53E66" modified="2025-10-08" version="1">MPSYVITGVSRGLGYEFLRQLSSDPNDIVIGTVRDKAATLKKVSEDADLKDRSNIHLLEVDLTNYEALKRAAEDAAKITGGSLDYLIANAAYVSEFDAYDPIGVLGTDKPQELEEDLKQAFNTNVVSNIHLYNLFMPLILKGQTKKVVVISTGMAEMELVNKYEVDVGSLYSISKAAMNMATAKFNAQYKKDGVLFLSISPGVVDVGKYTELTPHQTASMGGMMQKFAEYAPHFTGPMTPAESARAVRSVWEKATVQENAGDFISHLGNKQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXM2</accession>
    <name>A0ABR1VXM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline-phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666036.1">
        <property type="nucleotide sequence ID" value="XM_066814074.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047134"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16018">
        <property type="entry name" value="Enpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="685"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="640"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="759" mass="85205" checksum="341412282785376A" modified="2025-10-08" version="1">MSLHSNRSDQETDSEDDEVLARARNSQELRARDRLVLMEEEEMDRLVADTRAKKEERERERLRRTSSNLVIPNPLSILRRSRSNSPLDAIGVGGSTDTLVGEDRGERRKNRRARRKDKKDRLLQDARHGEDAGLMYEMESGDMKEGSSTGDSSDREGSDELDRRHLSMHSKTDKKRRWKRWLFLYTLIAVGFAFLVLLAWKISVDKKRATQKFVSNGTALFAPTSIIISLDGFRADFLQRGLTPRLNAFVKEGVSPLYMLPSFPSVTFPNHYTLATGLYPESHGVVGNTFWDPELQAEFYYTDPSRSMQPKWWNGEPFWVTAETQGIRSAVHMWPGSEAHIMDMEPSFLDPYKGKEKLPKKVDRLLELLDMPGMENPGVDVSDMRPQLIAAYVPNVDADGHKYGPNSTEIRTTIKDVDTMLDQLFHGLEQRNLTNIVNVIIVSDHGMATTDVSRMVQLDDVVDLDKVEHVDGWPLVGIRPKNPADLQVLYEQALGKLKDNPNYEVRLKDKDMPERYHFSKNDRIAPLWIIPKAGWAIVKKEEFDIQDAKAKGLEYDPRGLHGYDHEHPLMRAIFIARGPAFPHEPNSKIEAFQNIEVYNMLCDSVGMEPKPNNGTLRLPLKPIGLHDSESGIEELEDPETTTSTPAAASTTTTISTTSSVKNTVTTTVAAAQNLTSTPLIGVDPVKASSSQGSGVDPAVASPSKPLGVDPVETGPPERPHPDEDPEETHHFKSITELWDWLKDKAGHAWNKVHGGSDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYS4</accession>
    <name>A0ABR1VYS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665943.1">
        <property type="nucleotide sequence ID" value="XM_066813981.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047041"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="796"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="882" mass="98092" checksum="CC4773ECA26AC622" modified="2025-10-08" version="1">MVICPDVTAFATPLSKYSQLFKYTQHLNSALNEHQGADAAAQAYSNLGDAPRLLCEALLKPPLEAPILGPSSDLAGLELSFDSLDLSDHARGTRDANASLTRCHNDQRKTSSYFPEKYLEAIRGWKACLRGLHDKLQAGLLSTYSMHHEGEATNYMAEQLFNDHIFRAKAIQQMKHSKVPPSRSTRADDGVATFETRFSIYESVKEDLAYIHSLLQLCESGISLGRTTQEITISQRGDAVLEFANNESDSHPVLRFRVLSHMLSETSPLFARIFESEVGDSGDVLKEGFVPGLPQNPVEYTWGDGAQTRLYRMTQLELNAHGSFELLLHAAHLHNESVPREIEFDTFVALAKVCMRYQCTSPVEMFVEYRWLPQWMHKAIDDMPDGLLLISYAFGLRRLFTRMSKTAILNVIDEDDLQAKPWPQKMKDRIWAVRTAKMGQAMECCSSALQEYLRGPAASGRTDSGSDDADHDKKLAMGGGAITSSNPRCPKGNTCCDATNLGWLMILFAQLQILPHIMHSPAVAHLPPPPRRSLNQLFDSLRSIVSPPQGHGGVCEYAPTFRSAVNDISNSVQGLTLFEVSGQHGWALSRHKVDLPQLTFTAAKGAPPTDAVSMTMMMAAKMQTMRDSATAKVALRIMEYVDTPRDLRSIALVSKAFYSAYYSNAQYLFRRLNRVIGNTYNSNNSQLHRPGSVFEGDRQGGFRIDQQKVLIYDGDDDDNSTMVDHDFTATPPPSEIHDEQQQQQRQQQQGAAKMTREESARLLWASTNGYDGERSRSRGRVDDADHRLPGPAASSYPMTNPVGSSCGSDGLTQIDKVRTRRNEEGTEKFLASEVAVHFAVASRSPRAGMAPVPMPVPEDKNLVVTEDKNLREQRDRKVGILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7P6</accession>
    <name>A0ABR1W7P6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666976.1">
        <property type="nucleotide sequence ID" value="XM_066811634.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044694"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF13">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="60550" checksum="8972F87D097004B1" modified="2025-10-08" version="1">MANPEPEKLSGEQLSTEQLAGDEDAEDVEEVDAMSISSSKSVQNYEQIGVEWETEEFDYFNPYPVWSCEPEAHEVVELLKEVVSPLVEYNVKLLHKSAYSRFFEVEWDNERYVLKLTVPVCPELKTWSENLYSVSANNPVGCEWILMRKVSGKPLFQCWHDMEWSRKMRLVEQLAEYTARVYDNEFEGIGSLYPAAPGDPDHRPEHKGVEATMPFFWNGRYYKHRRQYGPYETYKDWAFDRLDLACADAEAVLPKLENREIRKIPWRIQALVAKLKELHDVLFTAPVAEEKEGPKGTTKDDPIDLLSDSEDEDVAELAGDNNANMSVPFNCEEKCMLWHTNLSMDNIFVDDTGVITGVLDWECVSAIPRSIGCQLPALLLEGHDRTHEPRLEHYWTFSDTIPRQSPIPSIEDEDEDEVAIASDDSENYLNGQPRGRPRHRRPHPQVGPTPAYWQARREWELTVLRHHFVRTMSDRSLGWHMCHKYHALKRDFETAVQYCDEPVLLDVVEAWVGDVGEGAAQKTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8C7</accession>
    <name>A0ABR1W8C7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CorA-like transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667213.1">
        <property type="nucleotide sequence ID" value="XM_066811871.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044931"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058257">
        <property type="entry name" value="CorA-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26616">
        <property type="entry name" value="CorA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="CorA-like transporter" evidence="2">
        <location>
            <begin position="2"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="372" mass="41782" checksum="6B966372D3945CE1" modified="2025-10-08" version="1">MQQQSMQTFEGAFAATLFTHLISFEWCSENWRWYIASLGDSMRKIQTKTDVSRLDPLDLPQFKDSANFRPADLLRMVSGHGKLTKTSKPTKATSLRLLSAVQGYLPSFAAPTSAPGAPNGTNIPLKPIQGTAGHVAAKQTNSHQSDPFKPLNMFTFGEYQTLQRIGERLQEAHLVIGLNIGILDKVTSSYSALAKSDQILNVSRKAVKSHVAQFLSRCASIRQNLKTQQHRLEVQIQILEGTKSLFNNILEFRNMEINKSFALNQYWSNMTMEKIAQRTAHETASMHIITLVTLIFLPGTFFATFFNGGNFNWDSADDGGPPWQFNLEVFGLFMKVSIPMMAVVTMVWFGAYWWARGTSRKELEDIEVGKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8I4</accession>
    <name>A0ABR1W8I4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007175</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666832.1">
        <property type="nucleotide sequence ID" value="XM_066811490.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044550"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="56"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8079357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="514" mass="57001" checksum="A2BFDB1AC90872F0" modified="2025-10-08" version="1">MERTKSSPAPSASPSKPVTPPANDASLQEQHRGLARFVPYFRNPDNVLRAKLDLLLLPWMFIAGIMKEMDQSATTQAYVSGMREDLGLLGNELNWFQTYFSIAYAIFIVPSQMMQTKLRPSLWLPFAEITWGLLTMFTYKAKTAQTIYVLRFFLGIMSATSWPGITSLILTWYMPAELALRLAIFQVSDVAGAMFLGVVQAQLYVHMNGVHGLAGWQWLFIISGAITVFLGLLGLLIVPDSPANTRAIWLTATEKRISRERMERHNIQPARLIPWRVLRAKLVLLLRHPLTWMFLAVFAQNAWAGRANSYILLYLKGVTDASTGRPLYTTYQVNLIPLGGYALQIVTNVGINALGDYKGWRWQICVVSGLVHIVACAILASWPTSHGVIMFAYFLTYATSAGGPAIIAWLAELLRAEPEARSIIVGLTVTVVYVGHATIPLGVWKVTDSPQYPIGFPLAAAFSACSISIVLLMRFWFVRKFPEFPRVGYGAGEEGVSDGPYTDDAEGVIVSKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9B8</accession>
    <name>A0ABR1W9B8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667117.1">
        <property type="nucleotide sequence ID" value="XM_066811775.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044835"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="100" mass="11116" checksum="3F7FB52ACBD24A93" modified="2025-10-08" version="1">MYISSHPSRLGRCGSRGTAIAYIHLGIEKNFGSDATESMSIEDPSCPRIRAVYAAMKAWDLSFDEAIRACGCYSMSKEDSETAVDDDDIMMETHDGWKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA10</accession>
    <name>A0ABR1WA10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667787.1">
        <property type="nucleotide sequence ID" value="XM_066812445.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045505"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047403708" description="SET domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="127"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="432" mass="49043" checksum="7CC7E077FA844E4E" modified="2025-10-08" version="1">MRRAHTIFTLLCVPLTQVYGKLLDSHNGQLLHLTSSTGSFCPWHRDYLSLTPEWAETERSPLGLVAGSCAGNLSQEICVYSNPSFGNSQGIAFLTSPKRAARLAQSTTLTDPSLHSQTERLNMVTNPKWEVQPIPGKGMGVIATSHLSLGDHVMSATPAIVQDSAIFELSDDEAMELRIRAVEHLPPVLRSAFLKLTTHDHAASLSERIEKIIDVNSFELDLVGDVEDDEGEKSWLAVFPDISRLNHACRPNAQYYFDPLTLTQHVHAVRDIHPGEEITVSYINAFQTHRRRQKKIASMWHFGCTCDFCSKNRHQIKASDERILQIQKLIKEFQDRTPRSKATPQAAELLISLYRQEKLWYAFYEAYTMAALEYSFVGEERQAIMYARLAIEHGIASAGPDDENVEMMRTLARDPRNHWSWMYRIDIREGNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAF4</accession>
    <name>A0ABR1WAF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667964.1">
        <property type="nucleotide sequence ID" value="XM_066812622.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045682"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007541">
        <property type="entry name" value="Uncharacterised_BSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33321">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33321:SF12">
        <property type="entry name" value="PLANT BASIC SECRETORY PROTEIN (BSP) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04450">
        <property type="entry name" value="BSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="277" mass="30492" checksum="B7FD48A7D47111E6" modified="2025-10-08" version="1">MPGMSYQHDAPPPPPTDAEPTPSPVPHPGGVSVTDSSGSPSSTKPPADTSSSSSKPSFDLPKLRLQLHDLAHPGSAIFLTSVVPPQVFSAAVQNVLSHLYTAPGHPHQHPPPTRSVTLILRPMGGVAYTTGIDLDDDHKEIHLSLEYVAGINPPGRRTHEITGVLTHELVHCLQWNGHGATPGGLIEGIADWVRLQCGLAPPHWKKERAAKWDAGYQHTAYFLEYLESRYGEGTVRRLNEKLRVEKYEEKAFWTETLGRPVEQLWEDYGKALEIQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAJ7</accession>
    <name>A0ABR1WAJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667958.1">
        <property type="nucleotide sequence ID" value="XM_066812616.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045676"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="27"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="718" mass="80324" checksum="DF2832572DED75E3" modified="2025-10-08" version="1">MKAFLSHLRRPAASSSTTSSQSLPEYPSLVNSLPVELHLQIVSYLDQDDVIACLHTSHSLRHICESPSIWPALADRWYPGLSTQLRLTVPVSHCGPAFRRFLTRNRRRSQGWFLSSLHHGMCLEDDEYFSAPLSRALPVAQGGVHEYAAVPDLCPLTPPLATSTATVMGPEATGEHSDRGHQYTRLAHFVAYANGRIAWWPEAYSLPYFAIVDDLRTRQRRGYLFPGHGEDRTGYMTSLGDTMLLMARGRTLHAWNFAGEAGGAESLRSVVMPQRIARTLSENDTVLIVSQDGEVWLWRPCFHHESNHQQQKEEPPRKIDIASARCYVPGHLLSDRYDIRDIAYRACRVGLRIQQPLSLPPAVAPSSSSSSMSGGGDNDDDFEQQALVATTNNNNNNNVITLDFVLHPARRDIFFLATLQDRKLTVYEFSTDGTLLGTFLPDFPSPSLHSTNSIAASSTAATTMTPEEQQPNYLLPTRWAAHRGGLRWEKTSASGDFSLLPIWLGGQQTNGPFDATGTVATAGAPVICPQCCDAGFVAVCFNVYSKTFTSGSSSLEAFRLWNGCLTERLSATTAEEEWPLMVLQPCRRRRRRGRMTRETEEDQRQEGETGPGEAGHIPLYTTTQTGRHEDDHPLVARRHEASLQVNWRTWQTLPLDSQKRLRRIVKFTLDPDQIFAKDRVHRQGSNPTPSLGVQSLWGDDDFLIYMNDQVYTAWQFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAM8</accession>
    <name>A0ABR1WAM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668036.1">
        <property type="nucleotide sequence ID" value="XM_066812694.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045754"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="675" mass="75386" checksum="13B2EB1E22936297" modified="2025-10-08" version="1">MDEYSQYITPQPGAEEASSHSFPSDGITQSQIPTMPMASSGAPMASSYQNLGFYTGFPEPIMFQAPKPPSSRGRKKSTPGLEHVKHRRTRSGCYTCRNRRVKDAARAKESAHIPNRLLGKALQDNRVRGDGSGQADSPGTASDEAEDEGEGDARLDTIADEEEPTEGGLRPQQSFSSLRRRSTASTLNLQRSGTRHSSETPSLEGTKSSSPSVSTGTSVSFATPSLPPDPSIQAGPSEWSHLPPDLHFYLQYFCDNMTHYSYCVVFDTDEFFMKFLPSVAVQSGNEALLYALVGFAAYHRTIQNPSGNISEFLQYYNKSEYLGDWVNLSGHQKAALQILMQLYTPQSAMQSFISRTILTWYVRFDVFVGMLGGYETRLPREWFSATVEYHESQRHSDPEGTLWKQEASSALLRLISVDMSFLYAKAKRGEVSGEAFAAEHAGLTAQLHKWRNNLDPSMIDPAYLETEFAWRQPLKDDDVVDSYAPGYLYKGHLFPTTLLLAEWHSVVVMHKSQEPGMLQQEPTQELVDLSMAICQLFDNVEKWPPRPSGTLAMLQACLVIAAIFVPRDQKHHMWMRRKFALIERSGYLAPFTIRSRMALIFRDSACIHWWIPNDDGFTPILQETRAFADERNGVPVSKQSEDVRDMASVFAKMRLDYEGVQSPTATPGSGPSGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAU4</accession>
    <name>A0ABR1WAU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008424</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668081.1">
        <property type="nucleotide sequence ID" value="XM_066812739.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045799"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF67">
        <property type="entry name" value="MFS MULTIDRUG EFFLUX TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="539"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="614"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="155"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="646" mass="69034" checksum="4175299770AF813E" modified="2025-10-08" version="1">MTGPDSDGNRNPPPWSGHGGTDQPSGDDDDDERTTLLAANGSYGTHHTNKPTQITGEHLHQHHHHNYFIDANESDLLLARTTSASTPGSVKSGHGSAIADTESVAGIHRHTANGNAEAAGTIDEEAASTSTATTANSPPSREFLIDTDPKLFRLIFGSVLLVYFIANFDGTIMASSHPVITSYFHSSNQASWLSTAFLLTSTAVQPIVGRLSDTIGRRLPYLFAMAIFTLATVWCALAGSIKSFILARAVCGLGAGGMISLGSIVISDMVNIERRGTYQSFINITYGLAAASGAALGGVMADTLGWRWEFGIQVFPLLGCFALVAWTMPPDLGLYVERETFVEAVKAFDWPGTALLMSSTMFLILGLNLGGNVLPWSHPFTIASLVMFAILFPTCLYAESRAQRPIMPLELLRSSPRANLVFANFVASFLVNAVLFNAPLYFQAVLLMSATASGLRLIVPVAVAATIGTLTGFLITRTQRLKWPLTLGSIGYARLALVGVLADPRPSAMGQGFQFPGTFIAVLRASAQAEQAVVTSTLMLWRALGNVMGVAGSSLILQNALLRYLRDYVGSDGTPQGDEAKLKLIAKVRASVEAVAALEDPVVREQAVRSYESALRMTFLCCIGLALVNMALLLPVKLPRLGARKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB85</accession>
    <name>A0ABR1WB85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-splicing endonuclease subunit Sen34</fullName>
            <ecNumber evidence="4">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008577</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668234.1">
        <property type="nucleotide sequence ID" value="XM_066812892.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045952"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006676">
        <property type="entry name" value="tRNA_splic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016690">
        <property type="entry name" value="TSEN34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059049">
        <property type="entry name" value="TSEN34_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00324">
        <property type="entry name" value="endA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26577">
        <property type="entry name" value="TSEN34_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017250">
        <property type="entry name" value="tRNA_splic_SEN34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TSEN34 N-terminal" evidence="6">
        <location>
            <begin position="10"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="5">
        <location>
            <begin position="178"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR017250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="278" mass="30811" checksum="C36AE02E75CD2AF4" modified="2025-10-08" version="1">MTSSSPRPHVRISKAANRYLVFDIDDVMYLRRNHNICSVFVGTMPQAPQQSAFMGLPIELMAEEAQVLVEKNVAFVVDDSNYHPARIAAAGPQDRQYLDAVKTVTSDAQRSMREQTEARKAMYANKGTTPAAATTTKNSPVTREAPEAWMATLTTSGALLTPSPGQDEQLASVDVPASYPLYAHLQDKGYFMMPGLRFGCDYNVYPGDPLRFHSHFQATGFQWNEDINLLDLVTGGRLGTNVKKSFLIGGRVESEEQHKDNTDATRDVRAFSIEWAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBN7</accession>
    <name>A0ABR1WBN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667355.1">
        <property type="nucleotide sequence ID" value="XM_066812013.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045073"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="625" mass="66530" checksum="AF6EDC95D96AB0D9" modified="2025-10-08" version="1">MAPPPVRSTSTQNAGSMSSTALMPAGVDGESRPRNRRGPSANDASSNPLASRSSPRLGPAPNAPSRGMSPLPAARLSTTKLADSGRSSPVTSSFSKGLLDGQWAPSWASVQELASSILTGGESGYNSEASQPNSRSASKSRQKSVWNTLGTNGSKNAGRNLPDSWGPAPPTRSGRPKAEDIAAGSLAEREAALKARKTASVLESYEGVNGGLDVAGKFKRRNSDENLAGTQSEPVVEDQLVYLHHVLPTDTYAGLILRYRRLRGQGPTVRTPNYFNRKVDHLATTPLPESSIQSGMADSWPNEQHPFHEDSSNPQNTKSQSLPEEEQPWTHVRWVKIDGVDNAVEIVRVPRQAVGFFPPRRKKSIRTVSAFSSPRQSLDLSRGVTGGSSEPAVDSPGNWSSSRRQSSISGARRPTVGSWEASSSTGRSRGNSLVSPSDGAPAWMRKPGGVGTMGRSTRAPGPAKDSLNTWVNKRLPKGFNIDSMPSMSVMGSESAHWGFNNTKPDEATGIVESPFEDGRDTNAMASKQGMGLEQAAATVETWLRGAWAKRPATPRLSSARRPAEDLDLIELTDTNSDDGGPRTPLRMPESNLQSSGSFGTSARSDGEGTVRGRTTSSAVKGKKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC75</accession>
    <name>A0ABR1WC75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667596.1">
        <property type="nucleotide sequence ID" value="XM_066812254.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045314"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="20"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="34395" checksum="27077E653F962FB7" modified="2025-10-08" version="1">MDPDIGDQGDVYKDISLDGDVVLVVGEEKKVRLKVNSQNLSCASKVFRTMFGPNWSEGQGLSKESPKEVELVEDDADAMYAICCVIHHRNDLAPKAISPQQVLQIAIAADKYDLSVALAYARAQWLRSRDIADPTTLAYLMAAARWFDDEPAFIKCGRALVLRCVGSYARLMDDEVLSQMLPSNIPHILEERRTRVRAELGELISNEAKEGCACGWGARRSKAFQQLARDHSPLKMLWTPVSQVMRNIQTPMVKLVDGPKYCPNRHFTHPPTPYARASQALEDARRKAIICYECVNASSKGTSCTSKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCA2</accession>
    <name>A0ABR1WCA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Caspase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007908</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667565.1">
        <property type="nucleotide sequence ID" value="XM_066812223.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045283"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="3">
        <location>
            <begin position="140"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="440" mass="47639" checksum="FCCD8BB591265D60" modified="2025-10-08" version="1" fragment="single">CPINKVTVGGYGGGGYPGGGYNQPPPQQYGGGYNQPPPQQQYGGGYQQQQQYGQYPPPHQQQGGQYGGPPPQHHNRYPAPNHPPPPGLDPYGYPVNSRPEYGHQGGGPRGDVPPPPDAPQHFGTGAPEGYTFQYSHCTGKRKALLIGINYIGQEGELRGCINDANNVQAFLMERYNYKREDMAHTPAQIMLTDDTSDPRLQPTKANILRGMQWLVEGARADDALFLHYSGHGGQTEDLDGDEDDGYDEVIYPLDYKTAGHIVDDEIHHVVVKPLMPGVRLTAIFDSCHSGTVMDLPYVYSTKGVAKEPNLAAEAGQGLLSAVSAYASGDMAGVAKSVFGFARTAFKGDGAHKKTIETKTSPADVIMWSGSKDDQTSADASIAQKATGAMSWAFISAIKENPQQSYVQLLNSIRDLLETKYSQKPQLSCSHPLDTNLLFVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCC5</accession>
    <name>A0ABR1WCC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ARP5-Actin-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668122.1">
        <property type="nucleotide sequence ID" value="XM_066812780.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045840"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="537"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="778" mass="88455" checksum="0BBAF9B5F35619DC" modified="2025-10-08" version="1">MAPSAVDPTVPGFGALPVREEKTYPPARIFPMKENRFETPTPEQPDGRQKALAQPAGSAAIVIDNGSSAVRAGWSFEAQPRFNIPPIMAKYRDRKLGKTYSFAGNDCYADTTARGHIRNAFEPGTGVVTNWDVMEHVLDWTFLKLGMNNAEGSIDMPIVMTETVANLPYSRKCEQETPIMSKYTVNPNARIHSYERNHLRGIWRTFPSNGRRLVVLLPTQQGPHRSGRVIIIQRYPRDTRLRFQGDIEPGNSPELGGWHAAEYLLKLIRLKYPSFPGKLNVSQAENMLKDHGYVSKEFDDEIRSYLDWTGLEDRDIVTQYPFTEEVIVQKSEEELARIAERKKESGRRLQEQAAKMRLEKLMRKEQELEYYKKLQEKIADSNKKDTKRLLDAEDMKDEAALERAIKELEKSVKKARTKDVGGDPEEEQEAPNFDLLDVPDEELDEAALKQKRHQRLLKSNHEARARAKAEKEAEKARIAEDERLDRERRENDLEGWLEEKRAIRNETLMRMKELDRLKADQGNRKSLASQIRMKSIANLASDGPRTKRRRGGDDDNFGANDDDWGVYRQIAVGENASDDEEGEEDLLGNLKTIEEDLLRYDKGFTHEDTYEAQSDWSRSLLHAFLRGPRPFDAGAQSEINQIHLNVERIRVPEVVFQPSIAGVDQAGLVEMCGDILTQRLVGIPTINRDDFLRDIFLTGGNTLFDNFDDRLRQGLTALLPVDSPLKLRRADNAILDAWKGAAGWVGSSGYKAAAVTRAEWLEKGGDYIKIRLLSPCPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLD8</accession>
    <name>A0ABR1WLD8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005627</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668865.1">
        <property type="nucleotide sequence ID" value="XM_066809942.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043002"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="36415" checksum="0D20315246973E27" modified="2025-10-08" version="1">MSQKKNTMQRFQEFRKNGDLPLTSRYLFTMTRPDLLSEESTHHGTAWGKGFIEIDFNDIEEWTEFNEKNANSAFFKVLDHPIPQGNHLNAPLAAIDQPKIIKVEEDIDNYFLQAIGPILRHSIECTRDLLRDKSGNDMALKLQVPFKTEAAKVRLPEAEGSVQHLKRPNFPIYLPAKSMPGMKPPKDVFFVIGESARTMVWNPDCFRERSEFQDHGHVHLGKVAMYCKAAGTCLAFTMTTVGATVFRFFTIENEDGIERWGVQLATFPWCPEPVKSGEENAMSAPKAIWTIIMMSLDPEGRRIQRRDNLRPLASWPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLT9</accession>
    <name>A0ABR1WLT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lactase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005777</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669015.1">
        <property type="nucleotide sequence ID" value="XM_066810092.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043152"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023230">
        <property type="entry name" value="Glyco_hydro_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF1">
        <property type="entry name" value="LACTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="LacZ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00719">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta galactosidase small chain/" evidence="6">
        <location>
            <begin position="710"/>
            <end position="971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="975" mass="109061" checksum="5D4E5C3F6166401A" modified="2025-10-08" version="1">MASEGPKPDYANLEVLERHRLPTRAFWIPETSVLLNGEWDFHYAESPLEAPEVGSDELAKADSWSRINVPGHWQLQGHGRPHYTNVIYPFPVCSPNIPTENPTGTYRRTFNVPSSWDPESQLRLRFEGVDSSYHIWVNGALVGYSQGSRNSAEFDVSSQVKRGGDNELVVQVYQWCEGSYIEDQDQWWLSGAEDHEVSCVLRDGSEQIASVTKKANDAKDAVLTIEMPISNPNKWTAETPYLYKVELSLSSGGDSKPFQTIAQNGLFTVNGRRVLLRGTNRHDHHPRFGRAVPLDFMRADLLLMKRHNINALRSSHYPSHPRLFDMADELGLWVMDEADLECHGFYDAVARPQDIPEEMDYEARKALTFPQSAKFTSDNPDWTAAYEDRLHQLVQRDKNHASIVIWSLGNEAFYGRNHAAMYDLAKRLDDTGRPVHYEGDVEAKSADMYSYMYPNMERLTNWVETVGVNAADGSFEKPVVLCEYAHAMGNGPGWLQDYQDMFRKYPRLQGGFIWEWANHGLWNEEGGFYGHGGDFGDEPNDGTFVMDGLCNSEHKPTPGLTELKKVIQPVKFEMEDGKVFITNEYDFVGLEHLVATYRIEALGEEATLLQSGELEIPQVQSWTKTELPLSYDLTKFSTAIGELFLTIRFALRTATKWADPAHEIAWFQTKLGNGAPLSPSSLVANTSTHNNNLGTGSGPLTVRDARTTCQVAGPGFAFVFDRVRGYLARWTADPATRAALFPSFWRAPTDNDRPGDWPYWRHYGVDALASQLRSFRAHTYLAPPILGWGFDVRATYTVTEAGVLRVRMRVSPTGPAPTHIPRLGLDVRLPKRLDQVRWLGLGPGESYPDKRGAQRMGVWGPASVDGGGSENGNRMGSRWVRVGDHYGAGIKATLAKTGEEEEGGGFSWTATRYSPEMLEKAKHPCDLVAADATLLNLSYKVAGVGTAACGPGVRDDLTVKVREEEFEFVLESTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN34</accession>
    <name>A0ABR1WN34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668936.1">
        <property type="nucleotide sequence ID" value="XM_066810013.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043073"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="134" mass="14971" checksum="9DE0BB1465FF3430" modified="2025-10-08" version="1">MVHTLKVPTAPAGVAVEEYQNLVASVIMACPNFEQLVGPIVTYDHTWNRLHHALSTRWKLREMNWVVGPSPYQRQRRIRSNSTAARMMAQSHNPQQLHAPPAICSRSRAWPFSTSTPTGAASRRCPSTACRAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNQ9</accession>
    <name>A0ABR1WNQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Guanine nucleotide-binding protein subunit beta-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006436</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669674.1">
        <property type="nucleotide sequence ID" value="XM_066810751.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043811"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045223">
        <property type="entry name" value="RACK1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19868">
        <property type="entry name" value="RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="11"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="59"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="101"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="180"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="280"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="34124" checksum="B16AB3A9976AEF20" modified="2025-10-08" version="1">MAEQLILKGTLEGHNGWVTSLATSMENPNMLLSASRDKTLIIWNLTRDESQYGYPKRSLHGHSHIVSDCVISSDGAYALSASWDKTLRLWELATGTTTRRFVGHTNDVLSVSFSADNRQIVSGSRDRTIKLWNTLGDCKYTITDKGHTEWVSCNPVIVSSSWDKLVKVWELSTCKLQTDHIGHTGYINTVTISPDGSLCASGGKDGTTMLWDLNESKHLYSLNAGDEIHALVFSPNRYWLCAATASSIIIFDLEKKSKVDELKPEFPSVGKKSREPECVSLAWSADGQTLFAGYTDNIIRAWGVMSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPW7</accession>
    <name>A0ABR1WPW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase group protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670083.1">
        <property type="nucleotide sequence ID" value="XM_066811160.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044220"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="829"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="780"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="854"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="868" mass="96713" checksum="274B5E68D5290A67" modified="2025-10-08" version="1">MKKTFKRDIAIFDAILPVARKLGSLDIKIAVFEWLWTEKLEGRRYEHLSRAVLLQSIDELQAAHAAEAEDFPRDQAERLKRCVAEYDNDNLLVEFLRLNWELGWHLDVKSLEAERYILAKFVGDAEYPRWVCSKGYYAFESATAPIKYYNRVSPHRPLHHPSARFRRAPLRNAQEEPEGLGRCVKSIGGLQGQHQKGAKGAAATAPPSPALVICRNKHWRYISSFHGPWLQLPLEVLETLANANYYMPLPRPVDPAVFYDLVKIRQLVDNATDLAVRAANGITTSPKTSSLAGGAAHQMAALGLGFGQGGMKLSPERRHKLREQATQKLSKAYRIDEIASSVATMQSTSTLENVAALVLQRAPNDADANYVNFFHEKIPSRQLAECTDLHTLDSIISQRPADCEPLRTRAIVRMFKEDFEGAARDLTSALNVFRLHQQPSHKLVYENKQLERRNGRRRELPSLDERDQPSSTEVQILFQRAGCYLTLACDHVETSLPQSAGETTPRDSVSEADSPDATRNMNGAGEQATPDANASSNEPTEEESRNMKRVRLYAKRALRDYMAYLEPLHYSPDMPIELSDDFTRQVNQANNRGRRYRGQNLTQDAAVLCHAPSGPPPYPSTDLVTASSPENLPSTTEMVTYHPLLTDALHSLLLCHALIQTSSKELQRHAHMVARLARLADGYPVFQASRSPARADWIEVLRRAENWIELSTSWEFLCAPAPLPTQMSLDGGGGGRAQKVMQHKAIVEALEDERVHDEASFKAAILARQRRAEADLANANAAPATNGNGNSASSPVVPSQKRWAVDDGREYPILTERAEAVARWVREAPAGAGVTTTKRKKRPGRKPTAAAPTNSTESLDSVLPQRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQQ0</accession>
    <name>A0ABR1WQQ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isoepoxydon dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670257.1">
        <property type="nucleotide sequence ID" value="XM_066811334.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044394"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF135">
        <property type="entry name" value="BLL7886 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="255" mass="27115" checksum="967E3FCB5A699512" modified="2025-10-08" version="1">MKLNLEKKVVLVTGGTRGIGKSIVAEFLAEGATVCFCSRTAATVESVEKEFSAAHPNSKCHGAVVDVSVPSQLEAWVSSVASAQGRVDVVVANPSALSMADTPESWNTSFQTDMMAARNLIQAALPHLEKTKGSIVSIATVSARDIDFTAPSPYGALKAALIHYTAQMAHTLAPKGIRANTVSPGNVYFKDGIWEQIEHAKPEFFAKQLKANTMGRMVKPEEVADAVVYLASERASFITGQNLNVDGGLCTGVQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRB6</accession>
    <name>A0ABR1WRB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dihydrolipoyllysine-residue succinyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_005829</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669067.1">
        <property type="nucleotide sequence ID" value="XM_066810144.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043204"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050537">
        <property type="entry name" value="2-oxoacid_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416:SF5">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="40"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="115"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="124"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8084558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="423" mass="46517" checksum="29AA9639FA1D9D68" modified="2025-10-08" version="1">MFSRRLLTAARVAQLRRPMQQPLRGVPLPTMMNQVRTYADTLVKVPQMAESISEGTLKQWNKQIGDYVEADEEIATIETDKIDVAVNAPEAGVIRELMANEEDTVTVGQEIAKIEAGAAPEGGNKSESKEAPKEETASTDAKPAEPKEESKPEPSKPAPPPEPKKETPPPKQSSQPAKDSSSAGPTLGSREERRVKMNRMRLRIAERLKQSQNTAASLTTFNEVDMSSLMEFRKLYKDEILKKQGVKLGFMSAFARACVLAMRDIPVINASIEGENGGDTIVYRDYVDLSVAVATEKGLVTPVVRNVEGMDMVNIEKSIADLGKKARDNKLTIEDMAGGTFTISNGGVFGSLMGTPIINLPQTAVLGLHAIKDKPVAINGKIEIRPMMYLALTYDHRLLDGREAVQFLVKIKEYIEDPRRMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRY4</accession>
    <name>A0ABR1WRY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_006504</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AFG1 ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669742.1">
        <property type="nucleotide sequence ID" value="XM_066810819.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043879"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169:SF2">
        <property type="entry name" value="AFG1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="122"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="513"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="513"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8085233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="611" mass="68416" checksum="04680CA971AB4610" modified="2025-10-08" version="1">MKRAATSVTITDPLVKYQSLLATGYYCSDPAQHRLAIHLQKIYKRLKDYSPSVEYGARLKAISNTLDESRRSREGSSSLAAANHPIRRNPLFSRFFASTEDRDSLALTRVLTGHEAAIQIDSPRGLFLSGEVGTGKSMLLDLLADGLPTSQKKRWHFNTFMLYTLSQLETYRKSHPQMSGGGDQQYSLLWMAREMIEKSPILFLDEFQFPDRAASKILSNLFTAFFQLGGVLVASSNRMPEDLEKATGFEYASPPPGAGGFLGQVLGFGKSRSRGRGELFGTSSDFSNFLEVLKARCEFWQMEGGKDWRRREMQEPRENELRLGSAITDVATGNTIKASQGMDPSTASEPVSSEEGLAIPRNYALLNETDDKDWTASLGNRSWEPLKLTVYGRTVRVPLQHNGVTYWKFNDLVSTYGPADYITMASTFHTFIIDEIPVLTILKKNEARRLITLLDALYEARCKLHVRAAAGPDDLFFPEAKANDHNLDPTSPTVDADAILPETIAEVYQDTTSPFRPNISSYTPDQTDPESDHQDSDFGISPAASRLDFSNTGAFTGEDERFAYKRAASRLWELCGAQWHARDDEGWWQPLPREARHWGERAGRDAVVVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS00</accession>
    <name>A0ABR1WS00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_007017</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670255.1">
        <property type="nucleotide sequence ID" value="XM_066811332.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044392"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="12">
        <location>
            <begin position="161"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="11">
        <location>
            <begin position="248"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="202"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="302"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="854"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="854"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8085746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="946" mass="106030" checksum="2FD0DF49FC75EFE7" modified="2025-10-08" version="1">MAAVQLSESHTAALGMLFNLQTSHRWGLLQEGDIQGSPEMQASYKAPEYRDELSRTIVETRLKLDSGAGDQCFDEYCAIEDGYLGKYRLIIIGALFMRAGAKIRDHDLQHLRDLVSQIRCTPEHASFDFDDSFRGPGKAQFLAALDHYAPGTPRDFYEPSCFTCGKIEADTGKAPLACARCKAVWYCDTACQTAHWKKHKRSCASPDQPQDSAGPRINPNPMSGSGAVNTERQMAPSAAKRQKKSAFSCHNCRSRKVKCGAERPSCQRCIKRGEDCVYKLAPTLSYTERLEQRIKELESEVQRLKGAHGSEAEAQTPETPEDASVSESTSRQPTEQLKQRLSGSYDGLKVDEKGVITYHGATSFFQAISGNPPKGPENEEQDEAGSSRSAQDMDRRQRLVNNAWHQRALECFTNIPEPFHYLLDLHWCWIQPLFNFVYRPAFTRDIQSNGPYYSHTLLSAIMSHSTRWAKRDPVIQEQLAPYEGGALFRRQARSFLFEELNRGVCTIPMIQTLLLLSAQECSSGNATQAWVYSGIAFRLVDHLGIFIDGQRYAADVHLSEEEVEIRHRLFWSCYFWDKIISLYLGRRPTLTHASVSPPGFMYDDSAEEEMWIPHGVTFAPGKQYPPTPAHSTSCFIKMCELSVIFNQILINIYDPLQQLSPSIIEDCVRTEGQALQTWWDALPHFLRIDTDNIPLYAPPSHIVTLNSLYHTFKILLFRPTLVKRSRQSSGERTQNQDHLRICVASAVSIAAIFDLFCRTFGEDHCITSLSYSLYIATSIFLLQVQALPGDTQALRRLLFCVQYLERVQTINPGKLRKAVPSRFPIWTTIFIGSALRPIKEVIAKLGLDQQAVAPQQTTVSTPETSEGGTFSSPGATTAGYGPGHHVRPSRDFQGDQFGTAADVDFSLMPDDMFEALSALEPMSVSIQPLDHTNASVQQPAWAFAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWN9</accession>
    <name>A0ABR1WWN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670438.1">
        <property type="nucleotide sequence ID" value="XM_066806820.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039880"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="33824" checksum="51AD3EFEED2A54E7" modified="2025-10-08" version="1">MAEQHPTAIPPGSLVLITGITSYVASWVAKDLLERGYRVRGVVRNLSQAAWLTQDVFPSFATAATFDLVEIPDLAAPNAFDNVIRESQPSAIIHTATPMSFDPDPHNVIPPVVSTMTSLLGSAARVASSSVKRFIYTSSIGAVYSPQVDTPATLTRDSWNYAAVEAAWAPPPYAPERGGKVYAASKVEAERSMFQFMEENGPVFTVASVDPFFILGPVLHERHLQGSAGWVRNVYGGEAKVAGVIPFGCQINVQDVAALHVAAVLDPDVKGTDCSPWPSPSTSTWFSPFYVASTQIDSLWRTSRRKVFAWPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWT8</accession>
    <name>A0ABR1WWT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670506.1">
        <property type="nucleotide sequence ID" value="XM_066806888.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039948"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="111" mass="12392" checksum="CEF86E87B7568E96" modified="2025-10-08" version="1">MENPVIHLLARAIHTLHLLNLHQAVFFFFFFVHLIHPFSNSIRDQQTREAAPLPLPLLHPADPGPRPPPLPRPTCPRHVCDVECRSGGAVTSACKGCCGPKKKKPEQEPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX52</accession>
    <name>A0ABR1WX52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002702</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670635.1">
        <property type="nucleotide sequence ID" value="XM_066807017.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040077"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="437" mass="48599" checksum="8020640CF5FD9AC7" modified="2025-10-08" version="1">MDPTHLHQLVGRLIHHDPRDDKKPEPFNYTASNGQICAMPRPLVETETAALAGGKTFYWLNLYVTAGCAAFTTVTIFVLMFRHATHLSRPNEQLNILRICCYLPIFAIGLFLEAAFPNSYAYLSPWLDFFQAIALANFFLLMCQYISPSDEQRDAFFAVFKVPASKASLCRGRRRGNKDGKNQEPNGLEWYRSLWWCIFQYPVIQFGISVFTDITEGARVYCLVSSSPHFAHLWLDIAHNVSLTMAVLAALRMYSALKKELAHHRPLAKLLAFKLLVAVTGLIQIVYWILRSSVPTDTLSWSDEYIGIPVLILSLLCVPFSVFFHHAYSPLAADVAETGYAANGINPVGTRYQGGPLGVWAWAGIFNPSEFVAGLRFGMKMRSNTQRRRGIYEEGAPLTAMPAGRGGGGYAGYAPAAGGEHSGESSPRHLGHHGYDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXD7</accession>
    <name>A0ABR1WXD7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670704.1">
        <property type="nucleotide sequence ID" value="XM_066807086.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040146"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="296" mass="33759" checksum="74EAE56FCE6E6BA4" modified="2025-10-08" version="1">MNGERQTDRVSEKATVTHADCSSSACKHSSGSILTTQKKDSNEEILKLLQAIQRNGERQIQLLEDAITEEPDMEERQEHMNQQPIAPEKKPNLAYKPWSSYEPWMGRHDEAATDLFTSSDEDQKLSMVIILGTLRVTPTLMDKLNVGEKAWSDMDPDLAQYIIREWLKNPDLGFSPYGETHAIFPHELLRRTCKVGTGPIRMSDNLFHFQHMAFVMEFMAIQAPRGPVLSNVEAAWDFTLAFVAPWKTIVQPSCTRHNGFWTSPKDSAHRILLETLTLQHFMRVFSTIQKDSSKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXJ2</accession>
    <name>A0ABR1WXJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670749.1">
        <property type="nucleotide sequence ID" value="XM_066807131.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040191"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="31429" checksum="1CFD5FDB79AAAA85" modified="2025-10-08" version="1">MVREALESYTDMDEFFRATPMGVMYWFFQRREPFLAQKTMTKWSRDRIDDYVLLPATPGFVTRTECFFVSHFWHSAQDPDPGGKYLQLMQHDLAQQSWSFIWVDWSCVPQHPRSPAEEAYFTRPRLWILYEVAEQALTSVGDLPETPDYKPFIEHVREMEQAGVRPTLERHGYRCTYDGDRDFLVSWLELLVLLRRLSIYVDDIRRMLDYQTWSPTLITILHQTWNGQLVQIRRFEGVVEYAGERHTFTPFPEWVTFSSRRSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXM3</accession>
    <name>A0ABR1WXM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphomutase-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670803.1">
        <property type="nucleotide sequence ID" value="XM_066807185.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040245"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="292" mass="33892" checksum="0FA68CB2D7C1BEB9" modified="2025-10-08" version="1">MSDHYHPLGDWAFTRADCVTLQRPYFQRNLRLIAGNEPDYTLPWDDNMYLIYPSEATPDWKKLYQHVKELNAISNQDSQYKIVYVMRRAHKKQVPSNPNEIDPEVSELGKKQCSTLQTGFERAITQLGLPPPDVVVTSPLTRALQTTQWGLAPIFDSSETLVLEGLREKVTGDGKNKRHSKSWIKEQFPQFDCRNVDDTDRFGATYCDPTNEEPYHEVWRRVYESLAFLFENRKRDPVVLLMTHCLVIQTIQREIDGWDVPEEERKSKEFYVGEAGGYAMIIKGERSRVSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXT4</accession>
    <name>A0ABR1WXT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA topoisomerase I</fullName>
            <ecNumber evidence="7">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA topoisomerase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002895</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670828.1">
        <property type="nucleotide sequence ID" value="XM_066807210.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040270"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00659">
        <property type="entry name" value="Topo_IB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03488">
        <property type="entry name" value="Topoisomer_IB_N_htopoI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.11.10">
        <property type="entry name" value="DNA Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.15.10">
        <property type="entry name" value="Topoisomerase I, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.41">
        <property type="entry name" value="Yeast DNA topoisomerase - domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013034">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013030">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001631">
        <property type="entry name" value="TopoI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025834">
        <property type="entry name" value="TopoI_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014711">
        <property type="entry name" value="TopoI_cat_a-hlx-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014727">
        <property type="entry name" value="TopoI_cat_a/b-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008336">
        <property type="entry name" value="TopoI_DNA-bd_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013499">
        <property type="entry name" value="TopoI_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048045">
        <property type="entry name" value="Topoisomer_I_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14370">
        <property type="entry name" value="Topo_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02919">
        <property type="entry name" value="Topoisom_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00416">
        <property type="entry name" value="EUTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00435">
        <property type="entry name" value="TOPEUc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52038">
        <property type="entry name" value="TOPO_IB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="DNA topoisomerase I eukaryotic-type" evidence="9">
        <location>
            <begin position="431"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="776"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="253"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="6">
        <location>
            <position position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8087934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="913" mass="103387" checksum="398D5073D090D566" modified="2025-10-08" version="1">MSSDLSDDNMPLARPNGKLSADTISKSEDKAMDKGDSAGTPLAAPVSIRNGPVQDGDAMDVDSPAVNGHKRKTRTSIGQKPSYKDDSDSDDQPMKTAVSDDSDDDVPLKRNTKLPPKASESDMLDMDSDDDDKPLHVKLAQKKAGIEKSAAKDAKKPTPKKKVVKDESDSDAPLASAKGKKRQSNGTVKSKTNGVKKEESDSDAPIRKKAKPAPAPAKGKTAVPVRGKAATTAKGKAAAPAAKKGTKAKKEESEEPAEGDEEEFEWWNKPKKEDDSTKWETLEHNGVMFPPLYEPLPKHVKLLYDGTPVTLHPDAEEVATFFGGMLHQPHHVENPTFQSNFFADFRKVIDETGGAKDKQGNKVDIKKFDKLDFKPIFEYMQAQSEMKKNRSKEEKKAESEAKKELEKPYNFCKWDGRTQKVGNFRVEPPSLFRGRGEHPKTGRLKLRVAPEQITINIGKEAKVPAPPPGHKWKAVQHDKTATWLAMWQENINGAYKYVMLAANSDVKGQADFNKFEKARELKKYIDKIRRDYTRDLRAEVMADRQRATAIYLIDKLALRAGNEKDTENEAETVGCCSLKYEHITLREPDTVIFDFLGKDSIRYYDEVKVERQVFKNLKMFKKPPKSEGDDIFDRLTTSSLNKHLSTYMKGLTAKVFRTYNASYTMSKLLGEMEANTHLTMAEKIAVYNKANREVAILCNHKRTVGANHEAQMEKLGDRIKGLKYQKWRTKAMMLAVDPKQKKKKGADYFALDEELDEQWIQDHIKFLVEEQRTKTTKKFEKENEKRKADGEKPHPEKELKARLKEVDELEKQLKKEAKTKKVEPEGKSPSVDKYETAVKKIDERIHTQEIAAADREGNKEVALGTSKINYIDPRLTVVFCKKFDVPIEKFFSKTLREKFNWAIKSIQDDEWEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY36</accession>
    <name>A0ABR1WY36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phytanoyl- dioxygenase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003039</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PhyH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670972.1">
        <property type="nucleotide sequence ID" value="XM_066807354.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040414"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF15">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="350" mass="38502" checksum="99133D7E10D439AB" modified="2025-10-08" version="1">MTTTAEDSPHGPYGGLKPSQLEAFHRDGYLIVPNALPPTTVKALLDETHTMLEDFSLADHPMTKFSTGERSAHVGNDYFLDSGDKVRFFFEEDAFSPETGELTKPKARAINKIGHYLHALSPPFAALLDPVYNPDLLGAGTTGGSVEAGRKESHPAAAARSLGFKDPRVLQSMVICKQPEIGGAVPPHQDSTFLYTDPPSAVGFWYALEDATVENGCLSFLPGSHRWAPVKQRFVRDAEGKGTTFMDNQGPKFPNAEEYGEHLQGGAKETDEYVMGEVKAGDLVLIHGNLLHKSEKNLSQKGRIIYTFHVIEGEGTKYDERNWLQPLRMDLRSCLEINCLLKFSLPIVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY47</accession>
    <name>A0ABR1WY47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP-activated protein kinase glycogen-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670948.1">
        <property type="nucleotide sequence ID" value="XM_066807330.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040390"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-activated protein kinase glycogen-binding" evidence="3">
        <location>
            <begin position="6"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="392" mass="43173" checksum="E17528815B34BAE8" modified="2025-10-08" version="1">MASKQVPVTITYRKPGTSPPVFLSGTFSDPPWQPKEMSYVVDDDSNHVFQLKTSAPEGSKIEYKFRLGPGDWWVLDETAGTVADDLGNLNNVMTVPASPGGGNIDDDLDDLADEDTADPPMLPHESYKPDDIEEWPINLPTTDQEVFGTSRKDEAEIDTNDPRFEHFPSENRHSIIAALRKIEGSVSEDGTSIAEDSVSHGHPLSPQISPMTPDPSTSPKSQRRSFRPDLPSDHAMELPRSPRSLASLQSIEETMEEEPSDTIEGRISGNDPEVLHDRRLSNVSPGSGITQTIKGPVVAPLEPRESASSEDEGISMAPNRKENDTNALRHRGKAKTPTNSRSKTPSSVNSTHGASNNGNWLQTFLHVVFVDWVGSFFIRFWNHFLRGKKGQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY75</accession>
    <name>A0ABR1WY75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671010.1">
        <property type="nucleotide sequence ID" value="XM_066807392.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040452"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050563">
        <property type="entry name" value="4-hydroxybenzoyl-CoA_TE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793">
        <property type="entry name" value="4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793:SF27">
        <property type="entry name" value="NOVEL THIOESTERASE SUPERFAMILY DOMAIN AND SAPOSIN A-TYPE DOMAIN CONTAINING PROTEIN (0610012H03RIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="17987" checksum="64DEF96A14ED15F5" modified="2025-10-08" version="1">MSTSTSQQLRQRSREDYPYLLEYRTRWADNDMYDHMNNSVYNFLFDSVINTYLMEHCGLKPPTSAQHPLMAHTHCDYFSAISFPSVAELCLRVNKLGKSSVTYEVGLFEKSADGVKAVGEFVHVFVDRSTLRPNASGMNDELRHGLQKLLVATGGSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYD0</accession>
    <name>A0ABR1WYD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671046.1">
        <property type="nucleotide sequence ID" value="XM_066807428.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040488"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF12">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="22"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="2">
        <location>
            <begin position="219"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="491" mass="56611" checksum="3A4DDAD4A4F0ED21" modified="2025-10-08" version="1">MRLIHCATLELKEFNECDVPEYAILSHTWGNEEVSFEEMIRPTPATYNKAGYHKIQNFASEAAPYCFEYIWVDTCCIKKESSSELSEAINSMYTWYKNAARCYVYLEDVEHFTAEDFRKCRWSSRGWTLQELIAPADVHFYCKHWDFMFTKEECVFVLSETLGIRSEILLTCDPSLASAAERMSWAARRVTTRPEDMAYCLLGIFDVNMPMLYGEGGIKAFLRLQGEIMKISDDQSLFAWRKKEEEGESLYSSYTGLLAPSPMEFIDSHNIEFVENSLENCPYSSTNKGISIRLNVIPSRADRHEPEVYIALLDCRYHEDHGPEGRAVGIFLRRLEGDQFARIDPHRIFNESHSRLFDRADPTDVYVRQSIRLPRGHRTPRVYGFVLSDQISIPGIYLADMWPVNCLRLLPSEQSKIAALCYRSRADPTFGTLAVLLRWDKKSMRFSSFCTKDSSWTEGTSIIDHVETMGRRIRGNDAEIRLVIIEATDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYU6</accession>
    <name>A0ABR1WYU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DNA mismatch repair protein msh-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003278</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671211.1">
        <property type="nucleotide sequence ID" value="XM_066807593.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040653"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03285">
        <property type="entry name" value="ABC_MSH2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011184">
        <property type="entry name" value="DNA_mismatch_repair_Msh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032642">
        <property type="entry name" value="Msh2_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF35">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005813">
        <property type="entry name" value="MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="10">
        <location>
            <begin position="732"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="907" mass="101959" checksum="0955C3CB199C9789" modified="2025-10-08" version="1">MSSRPELKLDDEVGFIRYFKSLPAVGNETVRIFDRGDWYTAHGDDANFLARTVYKTTSVVRQLGRNDASGLPSVTMTITVFRQFLREALFKLGKRIEIYASPNGRMNWKVVKQASPGNLQDVEDELGGFESAPMIMAVKITAKASEARNVGICFADASVRELGVSEFLDNDLYSNFEALLIQLGVKECLVQIDKAVKDKNPELAKLRQIIDSCGVAIAERPAGEFGTKDIEQDLSRLLKDERSTTLLPQTELKLAMGSAAALIKYLSVLQDPSNFGQYQLYQHDLSHFMKLDAAALKALNLMPGARDGAKTMSVFGLLNHCRTPVGSRLLAQWLKQPLMNRDEIEKRLQLVEAFANDTELRQTMQEEHLKSIPDLYRLAKRFQRNKANLEDVVRAYQVVIRLPGFLGTLEAVMDEQYKDPLDEAYTNKLRQASDSLGKLAEMVETTVDLDALDNHEFIIKSEFDDSLRIIRKRLDKIRSDMDREFRNAADDLNQEQNKKIFLDNHKVHGWCMRLTRTEAGCIRNNSKYKECSTQKNGVYFTTNKLLALRRDFDQLSQNYNRTQSSLVNEVITVAASYCPVLEQLAGVLAHLDVIVSFAHCSVHAPTAYVRPKIHPRGKGQTVLKEARHPCMEMQDDVQFITNDVELTRDQSSFLVITGPNMGGKSTYIRQIGVVALMAQVGCFVPCSEAELTIFDSILARVGASDSQLKGVSTFMAEMLETANILKSATKESLIIIDELGRGTSTYDGFGLAWAISEHIVKEIGCFAMFATHFHELTALSEQHQLERCFRQAGSHALYKVEPGICDQSFGIHVAELVRFPDKVIRMAKRKADELEDFTGKHEQNGLGHTKEEVQEGSARLKEVLVKWKKDVEGGNMSREDMVQKLRDLVKADQALLANPFFQSVKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZJ9</accession>
    <name>A0ABR1WZJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671466.1">
        <property type="nucleotide sequence ID" value="XM_066807848.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040908"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="679"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="752"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
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        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
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        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
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        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
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        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
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        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
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        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
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        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
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        <location>
            <begin position="539"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="602"/>
        </location>
    </feature>
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        <location>
            <begin position="620"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="910" mass="98993" checksum="2D3FA97DAF5E01BA" modified="2025-10-08" version="1">MPGGKTKHVLGANGLFSSQPKATGNSSRASSAVSDEDEAIMGYAEDDPASQNSQWRPEAVSSPRSASSRSNANRTKDQLPTEQVIREEDFSDDAGASITSGKTPNASRQSRGQDQSSADASESDIHENLIESEELDFSDDINGTKSEESAKSFGDEEYIPSQRSAGTCSQKALGGPARGVKQNSVRTGSVHSSKGGDHASAERVTTDESETFQATSAGRTTRVMPSKRRVAKKPFPSDNDDGNDASPSKAHTAISATTGSKVGVKDKNVPEAQTRRITQKGSNSVNPDDPFEIEGSPEPDTKQAPPAGRSRKTTNPRANSNSKPTVKSSREIMSDDIEDDDEPPLSLNASVTKPNSKKRRSSPQGYGSRPKKPKGPESNFLFGDRDSITVQPNSKARTDPKQFSPGQNVDHIEISSDAPSSDEAVEHLQLEIANSAEPAAQQKKQQLAANDSFTVNNSLEAPTRKPKEANTSSYTLPVSPPHQLNAPSHSGNDSFIVNAANYDSIVKAPSRIRAVPTVHRTGGRNKDTKAQQNHSLVRSGKDAIRVPENEDSSTMLSAPLSRDKTSNDLDPFADPRNSEEDKGAPNRLPPSQSVRDTISYGSRPQKAAAAVVVQADPSKDNYADANRWDSRATQRAAARPTQLSSAYLQSRSNHVTHPYGYNPLGQRIQRQHENINAGNVHARSSHSESKQDFSAQLNPKTQEYSHRFAAMQSLRRDNTQTQPFMPSPRRENSPGRLNVTSTEFISPEIQDQLGRRSRQNNQGFENNADGIQPRTSTEKIRTRCDDLVDGASEGIAAMLHDVVTAIHRQLAPKQDIIQDVVREYDRGGSKLTATLLKRQRGEFEPTVNTFHGSFQTMSKTFARAAQGIEAEGNAATRKTEAFENSYKKRKQHMCKLRESIRENLTGPGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZQ2</accession>
    <name>A0ABR1WZQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671551.1">
        <property type="nucleotide sequence ID" value="XM_066807933.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040993"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="92" mass="9919" checksum="CD78DD8F7F5D6634" modified="2025-10-08" version="1">MRNDADSENNRSALTATTSYATPTPEAPQSTPETVAATTAPVTTQGSSPAATTPASSPGQSYGNGNGNDYGYGYEQRYGYEHRQQKQYNNWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X020</accession>
    <name>A0ABR1X020_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">S-formylglutathione hydrolase</fullName>
            <ecNumber evidence="2 6">3.1.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003737</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Serine hydrolase involved in the detoxification of formaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>S-formylglutathione + H2O = formate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="3.1.2.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the esterase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.12" evidence="2 6"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671670.1">
        <property type="nucleotide sequence ID" value="XM_066808052.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041112"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014186">
        <property type="entry name" value="S-formylglutathione_hydrol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02821">
        <property type="entry name" value="fghA_ester_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061:SF0">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0719">Serine esterase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="291" mass="31634" checksum="7137520BE51C4D70" modified="2025-10-08" version="1">MASAFETKATIATFGGKLLKLSHKSNATQTPMDVNLYLPPASNDSKVPVLIFLSGLTCTPNNCSEKGFFHAAASKAGLAVLYPDTSPRGADLPGEKDSWDFGEGAGFYVNATAEPWKKHYKMETYVTQELPEAVFGAYGDKLDRSRVSITGHSMGGHGALTLFLKNPGMYRSVSALAPICNPSQCPWGEKAFGGYFGQDGDAKALWAGSDATELVRAKLKSGEKLPCLIDVGTGDNFYNQKQLLLENFEKAVKETSVEGVTVRYQPDYDHSYFFISSFAEDHVQHAAKYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X199</accession>
    <name>A0ABR1X199_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxidase</fullName>
            <ecNumber evidence="14">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_004121</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Forms a one-to-one complex with cytochrome c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="14"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672054.1">
        <property type="nucleotide sequence ID" value="XM_066808436.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041496"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00691">
        <property type="entry name" value="ascorbate_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 14 16" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="15">
        <location>
            <begin position="99"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8089160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="359" mass="39944" checksum="22889C4AC0C3F5D3" modified="2025-10-08" version="1">MSAANFSRQVARSALRTSARNTFSTSTRHAFRQSGRRFYSSEPPKPSGSSSSLVYLVGAAAAGVGGYYFYSQNASSAAPKVFTPTKEDYQKVYNEIAGRLEEKDDYDDGSYGPVLVRLAWHASGTYDKETKTGGSNGATMRFAPEGDHGANAGLKHARDFLEPVKAKFPWISYSDLWTLAGACAIQEMQGPTIPWRPGRADKEAAACTPDGRLPDGAQGTKHLRDIFYRMGFNDQEIVALAGAHALGRCHTDRSGFEGPWTFSPTVLTNDYYTLLLDEKWHIRKWDGPKQYQDKTKGLMMLPADYALIEDKAMKPWVQKYAKDNDLFFKDFSQVVVKLFELGVPFKEGTERMTFKPTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1J4</accession>
    <name>A0ABR1X1J4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Small GTPase superfamily- ARF type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004262</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672195.1">
        <property type="nucleotide sequence ID" value="XM_066808577.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041637"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="189" mass="20777" checksum="9A81B6626BD165D5" modified="2025-10-08" version="1">MGQSVSWLSSLLWAKKEIRILILGLVSANKLQLEQNLAGFSHSTLKIGEVVTTIPTIGFNVESVTYKNLNFNVWDLGGQTSIRPYWRCYYANTAAVIFVVDSTDIERLQTASEELAAMLNEDELKDAALLVFANKQDQPGAKGAGEISEALRLGELRDRNWSIMACSAVDGSGVHEGMDWLVQAPVSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X260</accession>
    <name>A0ABR1X260_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Casein kinase II beta 2 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672370.1">
        <property type="nucleotide sequence ID" value="XM_066808752.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041812"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038816">
        <property type="entry name" value="Stationary_phase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42342">
        <property type="entry name" value="STATIONARY PHASE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42342:SF1">
        <property type="entry name" value="STATIONARY PHASE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="47229" checksum="D7BA198CA830053E" modified="2025-10-08" version="1">MVAPLGGMWAPTALRMARQAVYKASKVIRAKLVNTARPVNAALEPVFARSTPRQPIHPAALLRQQKSRRWHSTSTYQNINSAVRRFMSTGRLSEAPRVDRAKFNTTQVGRAVSQFTGRAPFASTLRPNLTGGALPRTAGGYGLGSGRIGGPRYFSHTPAAQAQVVNNVSAAVRAFWISGQKAQFDGLTERGERRYRAVSSLQDETARKMATASRVSAGSYVDFKLNPTVTALSPLAGAFPYAAAGTKVPVADAPTLNAEGLFDVLSVDFGRALKDLTSTLGDLKKLAALGDLPIQLEKGHTIRVRFPGVDADTVETLCDDLEITRGIVGQDVDFEAEAGVTMALKFPFAPGANDQQSLTLTSPGGSLHSLGSFPDEDELFEAFSEVEKNPWLASSSSEPEGYESMSPPISSGEHCSEDFEGLQGVYRFLEECDRAQGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3D2</accession>
    <name>A0ABR1X3D2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Replication protein A subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_004840</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the heterotrimeric canonical replication protein A complex (RPA).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672773.1">
        <property type="nucleotide sequence ID" value="XM_066809155.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042215"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04477">
        <property type="entry name" value="RPA1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047192">
        <property type="entry name" value="Euk_RPA1_DBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007199">
        <property type="entry name" value="Rep_factor-A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004591">
        <property type="entry name" value="Rfa1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00617">
        <property type="entry name" value="rpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Replication factor-A protein 1 N-terminal" evidence="11">
        <location>
            <begin position="10"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="OB" evidence="10">
        <location>
            <begin position="187"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A OB" evidence="13">
        <location>
            <begin position="296"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="12">
        <location>
            <begin position="454"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8089879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="611" mass="67464" checksum="41293CE5C622CB0A" modified="2025-10-08" version="1">MSVAEAKSAITQGALEAIFDDAANVDQRFPVPVLQCLQIKPLAAQPAGGANVERYRVVLSDVRNYVQCMLATQANHVIHENQLVRGCIVRVKSYQANSVKGKNSVSILIILDLEVADNLGAHDRIGEPVAFESKPAGDGNTTIGGSGFYGAKSESPAVNAPQKSGAANHGGAVIYPIEALSPYAHKWTIKARVSAKSDIKTWHKPSGEGKLFSVNLLDESGEIKATGFNEQCDQYYDMLQEGSVYYISNPCRVQLAKKQFSNLPNDYELTFERDTVIEKAEDTSNVPQVRYNFVNIRALQEVEKDSTIDIVGVLKEVGDVNQIVSKTTQKPYDKRELTLVDESQFSVRVTIWGKTATAFDSQPESVVAFKGVKVSDFGGRSLSLLSSGTMSVDPDIEEAHRLKGWYDSQGASANFNTHSNMSSMGAATGRPDQTKSILQVKDENLGVENPGGDYFNLKATVVYIRQENFCYPACMNSDCNKKVIDSGDGTWRCEKCQADHPRPEYRYIMSINVNDHTGQLWLSCFDEVSRIIMDGMTADQAMELKETDEPALAAKFEAANCTKLNFRVRAKMDTYGENQKIRYQVMNATPLDYKSEALKLADMIKQFDMNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4C4</accession>
    <name>A0ABR1X4C4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Subtelomeric hrmA-associated cluster protein AFUB-079030/YDR124W-like helical bundle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673154.1">
        <property type="nucleotide sequence ID" value="XM_066809536.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042596"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047092">
        <property type="entry name" value="AFUB_07903/YDR124W-like_hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021264">
        <property type="entry name" value="AFUB_079030/YDR124W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36102">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36102:SF1">
        <property type="entry name" value="YDR124W-LIKE HELICAL BUNDLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11001">
        <property type="entry name" value="AFUB_07903_YDR124W_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Subtelomeric hrmA-associated cluster protein AFUB-079030/YDR124W-like helical bundle" evidence="2">
        <location>
            <begin position="162"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="576" mass="64954" checksum="059FFE171DEF1328" modified="2025-10-08" version="1">MVQGLNSSREGLPGRIPFSAEDGYITATNQRLEGRPKTIDRALREDARLEGSHYFVVYIDTTSEVQTLGLPQEKRSSITKFFNKNKFRACMLEDSNTSNQMSAGNSGTRRGLDTSYSQDYDGFEDANQFKARKRPRGGMLRQAADFGDEGLQTASSTRAISVSDEKELWDFYEQRFKDCQQTACKLIAKAWIKAVEPKKQSTHPYTGSDEKAPDWWPQPWGTGKEDRVRHKEPDHLYKRERVHLLNHILRMIVVPNNQQHADLKKLNLNVAKLKDVTNEALSGWFTDKDNPNNALKKPKLDEIFKVAAQEERFRHGQIGPTTKVHVKSDDRPGDGYASDRDETSQYRAEEEQENTPMSSRVSPTRIPTTQSLSFNGSSQSPNHIHSSHFMADLPARDAFHQQQPQHHHHQQQQPHQQIFDSHLAAEQQQQQHYVDNSGLGSHTAQPLHSHGGFSDMSYANHDTSRRPSMIPTPTTYQSPVTSAATYEWATTTHIPNATFPSHPAPSHASLMPPNMQHYILGDMGRDQNSAHAFRPDGMHSGHMGHPSGYQDYVQHDARGLAGGGIKLETQGHNMLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4U8</accession>
    <name>A0ABR1X4U8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Oxidase ustYa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005401</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673334.1">
        <property type="nucleotide sequence ID" value="XM_066809716.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042776"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8090440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="28307" checksum="BA4AA559CAE789BA" modified="2025-10-08" version="1">MATAGVTRYSMDSSRDSQDDDDGALLGHYQKRYRKGGYAGRGKRAARCRHPAVYFLSGLFAGLILVGLVLILYMKFATKRACSASLTGEVNSMVPEFPVRQVLFGRDPLATSDHTTEESKNATYNDWLSYMPVGNGFVALGQPKGNLLPPPIKYNDKDTYSVAYTHQLHCLHSIMTMYNGLLDGSMSAPTSHKHIDHCFRYLRQSIVCCGDTALEGQDPNRDVMGTDGTGAVHLCKDYDQLLSWTESKRVVDGHVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7Q6</accession>
    <name>A0ABR1X7Q6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_001801</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673412.1">
        <property type="nucleotide sequence ID" value="XM_066806116.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039176"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057246">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00132">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046812315" description="Peptidase M14 domain-containing protein" evidence="10">
        <location>
            <begin position="21"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="11">
        <location>
            <begin position="122"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="266"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="8">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8091440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="452" mass="50346" checksum="F12AFABC86619062" modified="2025-10-08" version="1">MRLLLLASLLAAPLLTGVAALPSRQDEEATVSYSGFKVYRINTLGRTPEVQDKLSALSSYEQWHQDAGHLDVLIAPDEAAAFEGLGLDYRVMHQDLGTSISAESPVANKKKRQDDPLAWFETYHNYEDHIQYFRDLHDAFPNNSEMVSSGKSYQGRDIFGIHLWGPGGPGKPAVLYHGTVHAREWITAPVVEYITLQLINGYNAGNNQTKSFLDRYDYYIFPFVNPDGFVYTQTTDRLWRKNRQPPPSDAANATCLGRDINRNWEHGWDSNPRGSSTNPCSQTYRGAAPGDSPENAGLDAFVRQVRDRQGIKLYIDWHSYGQYLLFPFGYAETLYAPELGKWTKAASMISETIRDSSDAATTYTFGGSGATLYATSGSAPDHVYSVGRAEWSFTIELRDTGRFGFVLPPEQIRPAAEEMWAGQRVLFSLLDETFFDGVGAAQVYQQQGVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7V7</accession>
    <name>A0ABR1X7V7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycerophosphoinositol permease 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673476.1">
        <property type="nucleotide sequence ID" value="XM_066806180.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039240"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="49"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8091504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="501" mass="54147" checksum="56A14C218343AFF9" modified="2025-10-08" version="1">MMTGAEEAPKAVAVLNSSETTNSSSSEDVVTPADAAVTAPAQRPAGKIDVLIQGVALFSDGYNIQIIGYMNTVLAKLYPKQMTAEVKTRLSNSILIGDVFGMLFFGLCIDRFGRRVGIILTTLFLVFGIILATASHGTTVEGMFWMMVIGRGVAGVGAGGEYTVCTSQALECADSTPEMRKRRGMLVAVSTNAAIISGFVASSIVSLIVIAAYGGEPSDGIWRICFGIGIVLPLSIFFFRMRLSDSEQYQKHAIQRKVPYWLAVKFYWKALLGCCSAWFLYDFVVYPFNLLAPTLVAGFSKNQSMIESIGWSALINFFALPGSFIGALLMDRIGRRQTYALGWSIVCVFGFVIGGAMVPLQHVFPLFVVFYALFQTFLSVGPGDCNFLVSSESFPTPLRGHFLGFAAAVGKAGAAIGTTALSEALASFDDKVKGQQVIFLIGSAISVVGTLCVWFLIPDLTDPILQAPKNLEDEDVRFRNYLEENGYDTSDMGLQAPKVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8N4</accession>
    <name>A0ABR1X8N4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="9">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_002173</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Lipid-anchor</topology>
            <topology evidence="1 9">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673784.1">
        <property type="nucleotide sequence ID" value="XM_066806488.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039548"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012946">
        <property type="entry name" value="X8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF2">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07983">
        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00768">
        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 9" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044960223" description="1,3-beta-glucanosyltransferase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="X8" evidence="11">
        <location>
            <begin position="390"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="498"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="509"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="553"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="576"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8091812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="613" mass="62704" checksum="E54AA007201507E3" modified="2025-10-08" version="1">MVSSLMKGAGIAALAFATGAAAVEPIVAKGKYFFYNNGTQFYIRGVAYQQGVGVGGSVADGQTTFTDPLADPKSCARDVPMLQQLGTNTIRVYAVDPTKDHKECMTQLADAGIYVIADLSEPGMSIERDNPQWNTALMARYTSVIDALSPFNNTLGFFAGNEVTNNNTNTAASAFVKAAVRDTKAYIAGKKEIGRWLGVGYATNDDSKTRDELASYFNCGADPKAAVDFWGYNIYEWCGQSTFRESGYEERTQAFRDYSVPAFFSEYGCNNPGGGEARPWQETSVLYSNLMNKVWSGGIVYEYFQEQNDFGLVNVDKAGKATPRKDFAPLAKQIKDFGYPAANKTMQMAAYKPAEKARQCPPVAKGSWEAAEALPPTPDKNTCDCMVSSLSCVAADNMQAKDMGSLFGTVCGLDPKACAGITADAKTGTYGAFAMCDSKQQLAHVLDAYYKGTGKSKAAACDFKGQAKLVNGGAPPTVASSCQPALASASASPVTKAGAAVDPSTVGGSDSGSGSGSGSSSGGSGSSSGGSGSSSGGSSGSGSSGSGSSSGSSGSGSSSGSGSGSGTGTVAAGAKSGNSTTGEPSTALGSRTSSSAWGYVAAIGAFAAGVMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8T2</accession>
    <name>A0ABR1X8T2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673853.1">
        <property type="nucleotide sequence ID" value="XM_066806557.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039617"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="158" mass="17093" checksum="4F001E934AACFB40" modified="2025-10-08" version="1">MPGKQTAEAQGAKSNAAINNGIRNPKGIRKGIISLAFLGLIPVTDYLARTGPLQWLLRQTVALIPGCAAASDITRGRMIPALSALYLFATYGASGAPSRSRARPWRGPRARARTSTRRRTHGGTSTSSRASRCGSAARTTGCSRTSRRMGSRRRWRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X937</accession>
    <name>A0ABR1X937_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_002256</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673867.1">
        <property type="nucleotide sequence ID" value="XM_066806571.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039631"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050054">
        <property type="entry name" value="UPRTase/APRTase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315:SF4">
        <property type="entry name" value="URACIL PHOSPHORIBOSYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="10">
        <location>
            <begin position="9"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8091895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="224" mass="23807" checksum="909A013520D77686" modified="2025-10-08" version="1">MSLPSNVHVSRHPCLLGKLSLLRSKSTSSREVKALVNEIATIVGIEALATALTPVDGPKDETPIGFEYTTTTIEPQALSLVPILRSGLGMPSRPLLPNPVPVHHLGLYREPSTLEPVEYYNNLPQHVSATTNEPTASLAIILDPVIATGGTCAAAIQTLREWGVKRILVLSVVAASEGIKRAANEWPDAVEIWVAGVDTELTGNGMLKPGVGDVGDRLFLTIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9G4</accession>
    <name>A0ABR1X9G4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YMC020W-like alpha/beta hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674082.1">
        <property type="nucleotide sequence ID" value="XM_066806786.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039846"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058934">
        <property type="entry name" value="YMC020W-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058933">
        <property type="entry name" value="YMC020W-like_ab_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47349:SF1">
        <property type="entry name" value="AER328WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47349">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26147">
        <property type="entry name" value="AB_HYDROLASE_YMC0-YMC35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YMC020W-like alpha/beta hydrolase" evidence="2">
        <location>
            <begin position="415"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8092110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="567" mass="60450" checksum="02B637DE21AAA9E0" modified="2025-10-08" version="1">MASRKRPRPNPPESTAANTTSLPVSLVSRLTGSTRRDRSSSQPNDPTASTASSTLSSTTAASSSSQDASQPSQMQREATDDPPAPPKSNPNIYQTATEEPELSIMGGTVKGAPADFSRYDTKKSSDTSGDSDRQSIKTLTKTTDSESQPNGNDTKKSGTESTASTVREGETENAATQEPSQGAPEASLSPTVAAPSEQPATSSGWLGWLGGYVITQGNAQTNNEETNKTPAPTQVPATVTQQETTMPPQDEISQTEPATPNQIRPTNSWFGGWLGTSVITNNEPSKTNPTQSEDPNKKEVEVTVTDEAPPTSTDHVTSPAAGSTWAFWSRDTGSKANGKTVTSQEQGELAVMGDGSESSPQRSAGVDARKRARPEAIGVEETGPARPETPTNKLVPAKPETPTSVQSVAPPNLLLPAFRHTYQMQQNPSILKQITQLLLRTQQPPPRHVYLVKEPPRIKKAMAIGVHGLFPAAFLRPMIGQPTGTSLRFANHAADAIRRWTDSHGCADCEIEKVALEGDGKIGDRVDNLWTLLLNWIDHIRSADFILLACHSQGVPVGVMLAAKLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA23</accession>
    <name>A0ABR1XA23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000205</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674293.1">
        <property type="nucleotide sequence ID" value="XM_066804520.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037580"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="377"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="464"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="100"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8093520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="498" mass="52633" checksum="EED845F23E5F093A" modified="2025-10-08" version="1" fragment="single">MGLPSLNWLLGRRSSPPDQLSESDPLLTGSDHGAGGANAGGNGTNIADEAVASAAQTQLRYPAPDNGRNEELSAGTTINEAAAFAAYARLQNKDGNNALRLGAAMYCFAVLGMFVSTTGVILSSVKADYGGLSDTQVSLLFLAAPVGYLAATQLNRHIHLRYGRRGIAVFGPLMHVTMAAVVALHPPFPVVIGAWVVGSLGHGTVDGSVCAWVGDLKSASAASGMLHGAYSAGAGLGPFLAGTLISRVGQGRWYEWFYVLVGASILELAIMTFAFRSDDAKSYNKHINNNALARLLSESSTRNSRRYRVVIGICASFLLVYVGTEALITGWIVAYMERVRHMSLYASSLCSTAFGLGMAIGRLVLGLVTEKFGVRRAVPVYIICATILDVLFALSPMSEHSVTPAIVLISLVGLCLGPLFPSAIVLLVQLLPRYLHVRAVSVVALVGQVGAALLPFGLGVMAELIGIQLLPLVVFICLAAMLVLWAWFARPSVRHVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAR2</accession>
    <name>A0ABR1XAR2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674533.1">
        <property type="nucleotide sequence ID" value="XM_066804760.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037820"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42055">
        <property type="entry name" value="YALI0E03476P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42055:SF1">
        <property type="entry name" value="YALI0E03476P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="614" mass="69416" checksum="018535CCA0A76F6B" modified="2025-10-08" version="1">MPIRFAPRRVSVLLVAIGIFALFTLFITLPSAIPTGPSLSKSIAEHKPSIPKIPKLQEFKDTLSTSLLKPFKPAVHPPVQVNSTDGESSWYSNWNWLRPFSSSVTLDENRSLLPPLKKRTPIYCYYDATIPREKETKEAESALLLTWRRAWWAQGFKPIILGAGEAMANPLYDELQRKEVEPKFKTNMMRWLAWENMAGGMLSDYLTLPMGAREEPLLTYLRRGEFPDLTRWEGFGNGLYAGPKNKITDAVTKALRSPEKKDSKDVIDAAPNDAFKIDKSHDGLAYYAPSIIDEKYPKVAEDLRRNRAAGLKSLNLLVNSHLHSTWQDLHPLGISVLKPMPAHTTHMIEPALSLAEWLSQCGDTPEPTTCPPNLPKCSPCVASQPMKLSTPARYRNTSGLYHIGTVPHPLTVATLDALKSEIDIAWVRRVMERDRWLYELTKEYLGVPLGGRGRILKFKEAVADEYATAHSVWLTAEHETLPHDLDWYFGFSIPINGTDKGTSETPVPGPERRPKKAHSADDGPPPNEDEYKLEPELLKRARDMGKSKVEKDVSVRNAIEAWNLADTEAWKFARAFLARTRVERLKWEEEESKYAEGAGSDRGKKRTAWDRWTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAR4</accession>
    <name>A0ABR1XAR4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674470.1">
        <property type="nucleotide sequence ID" value="XM_066804697.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037757"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052907">
        <property type="entry name" value="Beta-lactamase/esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319:SF3">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="16"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="400" mass="42753" checksum="6F9BA7CAB4DB127B" modified="2025-10-08" version="1">MAQAQGTCDPRFAKVRTLFQSFLDSGEELGASLTVNLAGETVVDLYGGHRDAARTRAWGRDTVVPLASSTKTVSALAVLLLVDRGAIASVNDKVCTYWPEFAANGKGEVEIRHLLAHTSGVAGWEDPVGMEEVCDRDSDATARLAGQAPWWEPGTASAYHAWNYGHLLGEVVRRVTGGTRLKEFIAQEIAEPLGADFQIGLRAEDEGRVSEFVGVEVGGGLPPGFRPGPLFVKAIANPAMPPDFGRTRAWREGEVGASNGVGNARGLNTILSNITLAGFNNDNKEQEKKKYLLSKSTVDLIFEEQSYGPDLAVGQTIRFGIGYALRGDADGGREKTWVDDRLPAGRIAYWGGSGGSLGIMDVDRGLTITYAMNLRSTSMLGNPASTAYIGAIYEALGVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB99</accession>
    <name>A0ABR1XB99_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BING4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000542</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674630.1">
        <property type="nucleotide sequence ID" value="XM_066804857.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037917"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012952">
        <property type="entry name" value="BING4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040315">
        <property type="entry name" value="WDR46/Utp7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085">
        <property type="entry name" value="WD-REPEAT PROTEIN BING4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08149">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01033">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="294"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="BING4 C-terminal" evidence="8">
        <location>
            <begin position="381"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="531"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8093857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="557" mass="63786" checksum="4A0AC7B9AD5A7E56" modified="2025-10-08" version="1">MEVDDLEVTERPSAKAHDNGAVTIKRARTQLIPKHERERIKRNKQAHRDYGRGNGIDVKTIKDKKLRRNLKGLEQKYKQAAESAKDAEILLENTSGFLEAEDELERTWRVTQNEIESNVSLEVSKKRFDLKLDQLGPYQFDYDRTGRMLLLGGARGHVATMDWRQGKLGCEINLQEKVRAVKYLHNTNYFSVSQKNQVYIYDSHGVELHCLRSLQEVSHMDFLPYHYLLATLGLTGWLKYTDVSTGKLVSEIRTGLGQPVSMALNPWNAIVHAGHNNGTVTLWSPNSTEPLVKLLCHKGPVKSVAVDREGRYMVSCGNDRKMAVWDIRMFREVNSYFTRAPASSVSISDRGVTAVGWSTSVTLWKDLFVKHRKDQIKVDSPYMTWGGEGKSVEQVKYCPYEDVLGIGHDEGFSSIIVPGAGEANFDAMEVNPYETVKQRRETEVKGLLNKLQPEMIALDPNFIGNLDLRSDQQRREARDLDAKPVDIETDIKNRMRGKNSALRKYLRKQRAKNNIIDEKRLKVDELWKQQQEQNQERRQEKAAEFGPALGRFARKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC82</accession>
    <name>A0ABR1XC82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000907</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674995.1">
        <property type="nucleotide sequence ID" value="XM_066805222.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038282"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="205"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="174"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="273" mass="30070" checksum="2818D3B4B9BBD989" modified="2025-10-08" version="1">MSYLNSWWAVSDLRQPARETSTRRPTVDGASTITQEFNPFYLPALSEGRSNIPKCSNQPSPSSSHPPNPPSASSSRSSGLWTASQHNLQPWEISVFEPTDFSFYGVGDQVGNTGSTSADWLTGIDHFGLDVPDAQWSGSLQPPQETAFDFTQVFQNDIYAFPLSSVAPSYSPALAATHSPSPESQSPDSSGTQTNSRKRASPPVDSSTALKRQRNNVAAKKYRQKKIDRITELEMELKGVRDERDDLKIRLARQEAEASALRSMLRMKSGSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCK7</accession>
    <name>A0ABR1XCK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675130.1">
        <property type="nucleotide sequence ID" value="XM_066805357.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038417"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="16156" checksum="A1B5671F2505883E" modified="2025-10-08" version="1">MAAAANDQAAPTTTTTSATTPASGPSYWSPAFKTRLQKNHERMRTDLEHRHNMMLMRAKRAKRAQKAILRLLLASKRRVREIERNLRKNRHSYQRRLQQIEWCRLRRIHGVQDGAGDAVADDDTEDEDEDEDYKIGPSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCX1</accession>
    <name>A0ABR1XCX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial</fullName>
            <ecNumber evidence="9">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Succinyl-CoA synthetase beta chain</fullName>
            <shortName evidence="9">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_001129</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>succinate + ATP + CoA = succinyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 11">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675217.1">
        <property type="nucleotide sequence ID" value="XM_066805444.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038504"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_ligase-like_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001913">
        <property type="entry name" value="PRK00696.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF1">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="45"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="89"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="364"/>
            <end position="366"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8094444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="48627" checksum="0FF7C0BE3580F7B1" modified="2025-10-08" version="1">MFKLARSRAAASALRSVKPQASTARFPGIAQQQRRNLSIHEWRSADLLRQYGIGVPKGSNAETAAEAEKIAKDIGNDDMVIKAQVLAGGRGKGSFDNGLKGGVRVIYSPTEAKMFADQMIGHKLITKQTGAAGRLCNSVYICERKFARREFYLAILMDRGNQSPVIVSSSQGGMDIEGVAKENPEAINTTYIDINVGVTDEMARDIATKLGFSEQCIEDAKDTIQKLYKIFREKDATQIEINPLSETSDHQVLCMDAKFGFDDNADYRQKEIFTWRDTTQEDPEEVRAAESNLNFIKLDGDIGCLVNGAGLAMATMDIIKLNGGQPANFLDVGGGATPAAIKEAFELITSDAKVTAVFVNIFGGIVRCDAIAHGLINTAKTLDLKIPIIARLQGTNVDEAHRLIEESGMKIFSIDDLQSAAERAVQLSKVVKMARDIDVGVEFTLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD79</accession>
    <name>A0ABR1XD79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001276</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675364.1">
        <property type="nucleotide sequence ID" value="XM_066805591.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038651"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013861">
        <property type="entry name" value="TMEM115/Pdh1/Rbl19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13377">
        <property type="entry name" value="PLACENTAL PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13377:SF3">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08551">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01160">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="272"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="35973" checksum="078CE6F53A86C266" modified="2025-10-08" version="1">MVCAVGNRRRVAHSCASVVAVLPWTFVTTTLVESNIFTLSIAGLTLFHGGRYLERAWSSREFAKFLLVVSLIPNMLCFLVLVMLFTLTRNERWTLTTIAGTIPLQISFLVAFSQLVPAHTVTLFRGILSMRVPKFPLIYIGVVTILSLTPLLTSASLFLSLFAFLTSWTYLRFYKTVFPDLDSSQPTSMRGDASETFAFAEFFPGPVKPFVAAFSDQIFNALVAMRVCTPFSPGDVSTGQGGSYLPRGAPGGVRAEAERRRALALKALDQRLHAATSTRSSSQPPNQTSGPTISTQPQSSTQTAMTSQPTAMLGETNYNPDHDHEKEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDW0</accession>
    <name>A0ABR1XDW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675562.1">
        <property type="nucleotide sequence ID" value="XM_066805789.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038849"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="171" mass="17712" checksum="61266E3048A7E43A" modified="2025-10-08" version="1">MPRGNNNSREAMVSFPLRGRQATGDDIHINLPASILPASSSTSGNYMRTINMRYNIPAETLDLSSHETYSWGPNNNTSGSSSATSSRAITSSADSSESTSSGSSSSDPSLDSPPSYSESVATGPSAIWSGGSYYTAPPQPRALRPPPLPSASTTYPTGAILVNEASFASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDW2</accession>
    <name>A0ABR1XDW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675654.1">
        <property type="nucleotide sequence ID" value="XM_066805881.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038941"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8897" checksum="2DB15EFBC71FC84D" modified="2025-10-08" version="1">MPISKKARIQREHKAAEKAGTRAPVKANGLPVKPPKPTSICQNCRKEIVNTNKVQLETHAATHDANNWPKEKCWPNDFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDW3</accession>
    <name>A0ABR1XDW3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675526.1">
        <property type="nucleotide sequence ID" value="XM_066805753.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038813"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027915">
        <property type="entry name" value="DUF4452"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39615">
        <property type="entry name" value="YALI0E17897P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39615:SF1">
        <property type="entry name" value="YALI0E17897P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14618">
        <property type="entry name" value="DUF4452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="205" mass="22829" checksum="93B431D3B000FEB0" modified="2025-10-08" version="1">MSQYYQYTHHQPTAPAPAPSHNHHGRNRRAPRLSVSQNSHRQFRGVRSMKELTESAVVSSFRNQFEVSRSFDLEDDMEFCPKLLTDSDMVSISSASSDRSSLSSNSPNSSPTQHPQQVASAFSLNSSSPAFIPPTYQSQQATLKLHQPAATPGSQRHPHHQPRQWPDHVQPAALGFARPDAAASWSTVVKQSPGPLFRTVSNWYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE90</accession>
    <name>A0ABR1XE90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongin-C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001619</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675707.1">
        <property type="nucleotide sequence ID" value="XM_066805934.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038994"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039948">
        <property type="entry name" value="ELC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20648">
        <property type="entry name" value="ELONGIN-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00045385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="94" mass="10846" checksum="D228C71982143F72" modified="2025-10-08" version="1">MAEVSKYVTLISNDGFEFVVLREAVLISPMIKSMIDSKMMEKVVEYFHYWYKNREKEDVPDMDIPAELCLELLVAADFLGLDSKKPLQQPHGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XED8</accession>
    <name>A0ABR1XED8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutathione hydrolase</fullName>
            <ecNumber evidence="1">2.3.2.2</ecNumber>
            <ecNumber evidence="1">3.4.19.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyltranspeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001704</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="1"/>
    <dbReference type="EC" id="3.4.19.13" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675792.1">
        <property type="nucleotide sequence ID" value="XM_066806019.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039079"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686">
        <property type="entry name" value="GAMMA GLUTAMYL TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686:SF62">
        <property type="entry name" value="GLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364023" description="Glutathione hydrolase" evidence="3">
        <location>
            <begin position="27"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="589"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU368068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8095019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="621" mass="66308" checksum="A3F432CF1969C975" modified="2025-10-08" version="1">MAIFKSIPGSLVALLLTASSPAAALATPPSWHQPDYQTGQAVFSHHDHLVSSSPSEQKLNSTKGAVASESKLCSEIGIDLLGQGGNAVDAWVGTQLCVGVTGMHHSGIGGGGFALVRDSSSAGSNYTVIDYRESAPAAAYEDMFKDNVRASVFGGLAAAVPGELRGLEAAHRRLGSLAWREVVRPAARVARQGFQVNEDMVRYMQYGVEYAGWNFLVEDPSWAQDFAPSGALVRLGDTMTRQRYADTLDAVAEGGADVFYEGPIADATIAALRAANGTMTHADLADYRAVLREPINITYGAHRLFSTGARLERGHVPRHPQDHGGLQRRLRSPPGRPGLPPRRRPGPARAPPPLRRRRRADPVQDPRQHDPAHRGLLPDRRRRRHQLPNPVPMTPVYAQASHGTSHVVAADASGMAVSSTTTVNLLFGNLLMVPSTGVILNNEMNDFSIPGVSNEFGYAPSPANFVWPGKRPLSSINPVIIEHASTGALFAVLGAAGGSRIISSTAQVAWRLLEGAAAVSAANQGSKEKNATTMLEAIREPRLHDQLMPNTAVFEYSFDNATVAGLAARGHNVTWVREGQSSVQGIRVLSRGDDGDDEDDDNTSIAGFEAVGRRGRRTVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUB3</accession>
    <name>A0ABR1UUB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660886.1">
        <property type="nucleotide sequence ID" value="XM_066818698.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051758"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="162" mass="18430" checksum="451916CCB008B0A9" modified="2025-10-08" version="1">MRRPMHESVVAKLQKHEVVPSTNPPGPIVLEVESSYCEGCQESKMRSVHESLHALQRDLADLNPNPSKLNSSNHNNDDENLLLRQEEDELRDVFRELEEAQLTAELAPRHFRGALRLFADICVAAIAPPERLRGWVETLTTNDYMVGDVQRAIEERLMRGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUL2</accession>
    <name>A0ABR1UUL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661202.1">
        <property type="nucleotide sequence ID" value="XM_066819014.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052074"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="199" mass="21010" checksum="DCF5CDFA7139C2FF" modified="2025-10-08" version="1">MGLPQNIVNSDCIAEPAARPTITVYVTQTSTACTDAVQIPHYNGYAAVVSMLPGVATDRVQYQPIKLSLRCQQRGRGQIPDGPGGPYSGSKDSTTSNPHSDSSGASPELGSGGLVLRPRALRRLGQESRPLVTAESGAYNIVPMNATDDDTSLVSRDGVAVGDVRGQLFYYLPDALEGLRPVAVPACRNSRLAAHRAPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUU2</accession>
    <name>A0ABR1UUU2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein 6- OR allele</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661292.1">
        <property type="nucleotide sequence ID" value="XM_066819104.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052164"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="156"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="673"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="908" mass="101602" checksum="A69DE3A3DF59ABEC" modified="2025-10-08" version="1">MSQPESTDIQGTKSPDIEAIDLDWDDYDIQIALDQLAGGSTEALKLFLARKEGVDPNTVSLVSKPWHAREEASVSFIGAVDDIGPPGGKKNIWASEPPPQARPIALKNTRTPYKYSELDPELRQFRLLKLSDPGEDGVIEHLELQTFSLSDAPTFFCLSYVWGDPNQFLAVNCNGGMVPVTQNLFHALRTCFDRYPDSWLWADGICINQQDFAERGFQVQLMGSIYEKTSKVLAHPGHYLYGKAESDSESEDNEPAMEEHIRGITIEDSQCPTAKEPVDPTTSTTLSKTTKSTDSYGIADFHHIDTGDAYSSTNVQSAVSIMTFLSRTWTVGNHDKTLSDTYWDKTSLPDLETQEGRRTWVNLLNFWSQDWYFRTWVLQEIVLAAKVVVLYRDTAISLDAITEFWSLAGSHGLPRVLRIGRIADMYNRVRHLSPVSSIKALRDRREKGLGIEGKADDTSTPSLLELLCLSRSNLATDPRDKVYGLLGLTDDDISRSIVPDYSQANTAARLFTDVALKLVLSAFTGDLLHHAGVDKNIPGLPSWVPDWTKQSRSTLPAHLYRRMGETTPKCSILDMEGGKPKLRVRGVIIAQINLAGAPWKFYSHDRSDPSFGRFKNAPDVDIAPDPSFNDEDARNLIFDMSSSFEEEIDIDVRYSGEEFQDAVARTLAADVSSQGHRIGRRTREASTDVPPRDPSSPAPNVPACADSDDFFAGLDAYRHFYARGPTCIEDLEAPGIRVHQTGSFMWLLDFDEEVGADFQHRMLQFSGPFQEAHRGRRFALLGTSVEKDENGEEAEEEQENYFMASVPWDAENEDYCVLLEGFRTPFILRKTLQQGQQQNSIVDGSGEEGFELVGDCYVHGIMDGELLSWADEIDEELGPEFRSINDKGREYVVRAPQGYVPFTDFVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVE4</accession>
    <name>A0ABR1UVE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661492.1">
        <property type="nucleotide sequence ID" value="XM_066819304.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052364"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="26"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="296" mass="35002" checksum="9ECABC25744EBDC1" modified="2025-10-08" version="1">MEDFSGFKDALGLPIEPLIPDHDAEFKLFSRLPVELRLKIWRATWTPKNIGPEKTSGWDYEIRQSKPWAKLPVTAIVNQESREETLRVYRKIVCSYPHVIDSYFNPEIDRLCFELIESLCPDMDPAQFLTVQKLSLSTYIYYEDWDYPESGLHGYKTFENFLHHVKESYLPSLREIRLELHSRLNFDIYPLQIEQVREDMRDSICAKHFFRYKEEGTGGVQIIPRHEDGRLMGFEILFLNQREAVYVTGEAELAAKHRAWLEFVGIALWNVLEPEAFLKKDRIDNYLVDQQDPYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVJ1</accession>
    <name>A0ABR1UVJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arylsulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_015035</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661537.1">
        <property type="nucleotide sequence ID" value="XM_066819349.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052409"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16147">
        <property type="entry name" value="G6S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108:SF8">
        <property type="entry name" value="SD21168P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="3">
        <location>
            <begin position="130"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="722"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="724"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="745" mass="80691" checksum="641F5B2A8B0975D3" modified="2025-10-08" version="1">MNATPPRQQMGSILAVNGQHHVVAVPLVANQSRSSYVSNKQRHPTCVRNFSAGPQLSPEGVDVGGCGAFLASIKFDGLGRVLASPFLVSIPPSAPNPSLGIFLVMRVSQSICGLSLACAASAAAGDATKPSIILIMSDDQDRRLGSTDYQSVLHREIYSQGVEFVNHFATTAQCCPSRASFLRGQAAHNTNVTNVHAPGGNYDKWHQAGLDEDYLPHWLKKAGYKAEYVGKFLNGYNVVNANITPKGWDHVDALLDPYTTYYNVPVMSQNGERPVYYKGFHSTDVVRTKALERLQSLVTQDQPYYLQIAPYAPHVQNDVHHTVPLARHMDLFPDAKAPRTPNYNPDDAHHRIGGWPGTLPLMNQTTMDTADGAFRARAQALQGLDEIIEDVIAMLDANGKLDNTYVIYTSDNGYHIGQHRLPGGKALFYGEDTNLPFGVRGPGVPKNMTSQIPGVHLDLVPTFLDIAGLPKEDWPTFLDGQSLLPQWKDPAGSAAGANAGDGNSKETLNVEFWGSCTIEAPNGAELGAPFVNTTYKTLRMLGDRQSWLFSVWCTGEMELYDTAADPYEVNNLAGAPEHEAALNRLNALLLVTKSCAEGTCRDPWSVFTPSNGTDEKIATMQQAMDSKYDAYFAAFPRVHFASCMQYQDIANEAPFYPASAGGPKGLGLGARRPTDNFVTTDAGVAIADAHFYGTPEQRHATLEQVYAQARNLTDAELAMPAAPKKGKGKGVRAVRRRRGGGAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVS9</accession>
    <name>A0ABR1UVS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_015138</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661640.1">
        <property type="nucleotide sequence ID" value="XM_066819452.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052512"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8063041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="463" mass="52213" checksum="79481C57446CEA98" modified="2025-10-08" version="1">MQDTRASQDSHEAGPSRKCGPYLYFKCDQCRKDKQKCLPKEREPNTKCDRCCFKGFQCSSNSTAASAKHSRAAEGASQTPVVQSRRTNFLSAWQWYKRLHHILSGTNIGEMERTKAMMAKFCTKMTSELTQLYQNAWDTQDSAAQALLSRTWSVDQGCFGRIGGSTGEPSSTATSAILRILPQPHESRWKDNLTAADIGWSSGESADVLRYLLRRLDFHLTDYRLANNDERACVKHLTRKYFDYANQFRTTNTRLFNNDYLDLKGDIPELESFTEMRQHIKDSTSDECIKYLEYLLDLDSGYSTTVYSGGDTLLHTACMNAPDESRGKAVQHLLSQGRDIRINQQNLAGETALHYCCMSIASCLLHKYPLAPHLASLRLLLSHPDIDVDVRDFSDSEGGKVASFCCRRGLGIRLKNKTGSSHFFNASNQCTQAMIYQAGKTLIQRESLLSTRVVDHDIEIRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWM2</accession>
    <name>A0ABR1UWM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661049.1">
        <property type="nucleotide sequence ID" value="XM_066818861.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051921"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="285" mass="31646" checksum="64738E2920D02A1D" modified="2025-10-08" version="1">MEGITASHRLEDVALLARQRPETEEATWRLLGALSFMSPIHPIPYSVFQPAASSSSPPTSPTDSKKDASGVKARARRELNDRKMLQDPLPWVVISTEHDTTTTPTTQQANAGTLITNNSRARSGSVLVQNLFEEALQPLLETAIVRRSHVRGPIIHIDAATQELYRAQTIKRHGQRDFDLAVRMLLQAKPTPSSIISSSSPTVSDTIQTQLAHHVLALTCHFEKYADWPHGDGKDSSSTVAAAAENKKEKDAMDHMFVRPPRFVTTKELEQLTKRTLEWSGYHEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXB1</accession>
    <name>A0ABR1UXB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661063.1">
        <property type="nucleotide sequence ID" value="XM_066818875.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051935"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF1">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="295" mass="33332" checksum="A79724021803C881" modified="2025-10-08" version="1">MADATTPLLPGPSNTGSSDSHPIFLRACHSPWRFINQSVLTLFRFVISAYLLTVMGISLKYKLETEDDHTRWRIPFQFSSVSFILLLLYNLQVTVWTFMHLLLPKELPEEPAECHGHQFRNKIINLLLPPSRNRYGNHTHPFWFSMFYTVSHVFTFMNTIIYWAVLVPAGHGGFEPPNALIVTPMRLITQRLLDKGLFEEGHLKAFSIINVWSITSAIAVLEILVFNSIRRQTLGKLVTGHAGLFFLDPELMGDAHGAALAASVLFVSLSPGIFSYMYGLIAMRESMSAIHETPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1H9</accession>
    <name>A0ABR1V1H9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661803.1">
        <property type="nucleotide sequence ID" value="XM_066816111.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049171"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="18"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="251" mass="29078" checksum="ED77E36D2B8FEFF5" modified="2025-10-08" version="1">METQITTSAQANETAPTFHPFPRLPIELRMQIWEELIPETRTRLLWVREPGWMKLDKKKFASILLSISQESRSIFLKRFPMGLKVCQRSMTLRKTDSSFPRLTVSWADRGVVYIHPERDVFVIGQPWPEYSTCAEPGLPFTGDEFTLLAKPLRRQKPRDRVRNVIEFEHTMVDTPGAFDVNFSEEPDSETELIPEDVDGKPTDDWNFGGVTRRLKLTAPLEHEEILKFYEDSKELSGSEMLENWGGKFTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V469</accession>
    <name>A0ABR1V469_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_012710</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662716.1">
        <property type="nucleotide sequence ID" value="XM_066817024.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050084"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8065963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="596" mass="66078" checksum="612E267BFF1CB07C" modified="2025-10-08" version="1">MKDPVQRTASPYTDPSVKGPRSQQLFSHTHSLLHNHKMIAPNKVNKTALHPGGIEPHQEAEHTELEIELHDKAHIDYDRVAIIPNPSVAALYEDALVYEVGSAIASSGALTAYSGAKTGRSPSDKRIVKEPSSENEVWWGPVNKPMAPEVWKINRERAIDYLNTRTRIYVIDGYAGWDEKYRIRVRVICARAYHALFMRNMLIRPSREELEHFHPDYTIYNAGTFPANRFTEGMTSGTSVAINFADKEMVILGTEYAGEMKKGVFTVLFYEMPIKHHVLTLHSSANEGKNGDVTLFFGLSGTGKTTLSADPNRALIGDDEHCWSDRGVFNIEGGCYAKCIGLSAEKEPDIYGAIRYGSVLENVVFDQQTREVDYDDSTLTENTRCAYPIEYISNAKIPCLSNSHPKNIILLTCDARGVLPPISKLSSAQTMFHFISGYTSKMAGTEDGVTEPQATFSSCFAQPFLALHPMRYAKMLAEKIEQHSANAWLLNTGWVGAGYTHGGKRCPLKYTRAILDAIHSGELANVEYETYEVFNLPVPKTCPGVPAELLNPATAWTAGADSFQQEVKKLGGLFIENFKKYESEATPEVKAAGPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4J2</accession>
    <name>A0ABR1V4J2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012862</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662868.1">
        <property type="nucleotide sequence ID" value="XM_066817176.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050236"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="247" mass="28584" checksum="B95A2A6DD5A82FF5" modified="2025-10-08" version="1">MDQMIPGDGGRNPLEAWFWEMPICTRWWTTATVLTSALVQCQMVSPYQLFYSVRTVFTKGEYWRMLTTFLYFGPFSLDLLFHVYFLQRYSRLLEESSGRSPAYFSWLLMYSMAFLLVLSPLVAMPFLGHPLSSIMVYIWSRRNPDTRLSFLGLLVFTAPYLPWVLMGFSLVMHGTIPKDEIMGVVIGHIWYFFTDVYPPMHNGSRPLDPPSWWRRIFEGRPREEAATAIDNEFSVGGGPDLAAAEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5M9</accession>
    <name>A0ABR1V5M9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013255</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663261.1">
        <property type="nucleotide sequence ID" value="XM_066817569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050629"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343:SF10">
        <property type="entry name" value="RNA-BINDING REGION RNP-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343">
        <property type="entry name" value="SERINE/ARGININE-RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="222"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="287" mass="30902" checksum="22305B2486178E01" modified="2025-10-08" version="1">MAPNTTVNVRNISSSTSEKEIKDFFAFCGKITDLKVTTDANGTQDATVIFEKETAAKTAQLLNNTQLGGSQIEVIAEDAKNDDTAYASNADRDSDEITQEEKPRSRILAEYLAHGYVVGDAALQRGIELDQKHGVTNRFMTTLQNLDNKYHATEKAKATDQSYGITQRASSLFFGLGSYFEKATNTPTGKKLVDFYTVSSRQVQDIHAEARRLADLKKENHGGSAYKASGLERVFGKEQPAAEGSNTTGATDSTGVPQPGPKAGTTESTPLDPTGPLPTKEPGSEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5W6</accession>
    <name>A0ABR1V5W6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L37ae</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013343</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663349.1">
        <property type="nucleotide sequence ID" value="XM_066817657.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050717"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00327">
        <property type="entry name" value="Ribosomal_eL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050522">
        <property type="entry name" value="Ribosomal_protein_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00280">
        <property type="entry name" value="eL43_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003058">
        <property type="entry name" value="PRK03976.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="92" mass="10135" checksum="2326027CEDDABF06" modified="2025-10-08" version="1">MTKRTKKVGVTGKYGTRYGASLRKQVKKMEITQHAKYTCTFCGKVNVKRTAVGIWNCRACHKVVAGGAYTVATPAAAAMRSTLRRLREIAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6L3</accession>
    <name>A0ABR1V6L3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013583</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663589.1">
        <property type="nucleotide sequence ID" value="XM_066817897.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050957"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="46"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="88"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="130"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="21755" checksum="D878A16EACDC053E" modified="2025-10-08" version="1">MRFEYYINILLIKNISIATYKPSPKRIPVTQAPTVDRDWNACQQTLEGHGHFVESMAFSPDGRLLASASSDKTVKVQDAATGRVKQTLEGHGDFVGSVAFSPDGRLLASASVDKTVRVWDAQTGQEKQTLAGHRSPVRSVAFSPNGRVVASASNDSTVKLWDAATGQELQTTVIGTASSILSFSPDSSSIITAAGAIFINCQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V710</accession>
    <name>A0ABR1V710_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012586</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662592.1">
        <property type="nucleotide sequence ID" value="XM_066816900.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049960"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="790"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="864"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
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        <location>
            <begin position="200"/>
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            <begin position="292"/>
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            <begin position="334"/>
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            <begin position="365"/>
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        <location>
            <begin position="617"/>
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        <location>
            <begin position="663"/>
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    </feature>
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        <location>
            <begin position="725"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAK8065839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="888" mass="95719" checksum="B9CB12F9C90DE9A8" modified="2025-10-08" version="1">MSPPTSSSSSSSQSPRRPLHERSKSDSNKLPGIRLVPYSPPRLSHGEGEPSSSHGTSSTAGADSSSYEYHTTSDEGSSSPTIREGRKGSLPFIIGTGSALPSPTSSTASLVRAKGKGVSGPKLGSDLSGAPTPQHPVNSRASYGSNNSRLNPPSDTSEYGDPATPTQKFVRSKADRFINVHEDKTFSIVLKPTGIRQPRDQGSSSQATSFKSPPLSYASTLSSAHERISFDTTTVDHPSSPPSSVADVNLSPYTPYAPGFASYTPGSTKFNDRIEEEVDPITSSPNYRMEDNNNDNDDDEEDDEDELPQPRLPSLPEVPSSPPRLPSPLAEKPSFSSVSSGQTDSSLEELDNFEILGRSSPPLPRSNNLESTPSPDLPYSENFNATPSSNPNYQVLGESSPSQPFASSPGPGFSNTPASQNYVVHGEPSSSSLGTSSREPRPQTSDDSLVLRGKYSQESLVIPPLIPRKQPSGERLGYHKQKSSRSLRRANSFSSLSSIITEGSASIFFAQTANIIRLGATPAITAFHPPQRAKQQHHSWAGPSSIVAQRPRMEAHPHQWSSQLSTVASEDETSDRASRPLSSLSGPDYRMSQGSRHSRQMLSISSSLAFAEEPPVGSSRSNLSSASGSESRGSLPIRVVRDVDEDGDGITDLRDLVHKNSSRLLSSKSSDGDLYSSSSSGRRPKSRTGSFTSTLPVWAKVYYGSGERRWAAAPSMRSYSDDSRPGSAAMPSGSPSVDPFPPNVFSPRRRPREIQPNNGHASGKCHRYLGTSIDDLVERQGKLGRRNMQIVMFALGWIFPFAWMIAAVLPLPHKPLPQMTMADHHSTAELGGQISTPDIFSGRVDPAEDANYQSARWWRNVNRLMCVVGLLIIGAIVALIIIGTRENW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7L1</accession>
    <name>A0ABR1V7L1_9PEZI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
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        </lineage>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067148.1"/>
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    </dbReference>
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            <begin position="41"/>
            <end position="63"/>
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            <begin position="139"/>
            <end position="356"/>
        </location>
    </feature>
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        <location>
            <begin position="140"/>
            <end position="152"/>
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            <begin position="156"/>
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            <begin position="339"/>
            <end position="353"/>
        </location>
    </feature>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067148.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="417" mass="42654" checksum="20A56A7CB5932429" modified="2025-10-08" version="1">MAPMGLPVYRDEKACLTPETRSTTPASCKCKSQRMSSTRKCCLGLLIVLSVTLGLATTTIPGVNSNSAEGQGIVEGHGSGISKDMGSVSSDTLHKMLHKCFPGSFKDGVFPSDEEALEAIQSQDATVASSLAELARRQNDNATASGGSTVTSVDGAPTTTKAPETTAKPTEQPTTTEQPKTTEQPKTTEQPPPSPSDNKPTTTANPPTAQSTTDKPEDTPEPTTTANPPPTTNQPQPPTTAGTTETAKTTETAKTTETSKADKPGTSVTSAKPAPETPKTVTVVSSPPAAAPVTITTTQNAPPVTSTPESPASTTPENSPTQETTQEATTAQATTMQTSEKPFTTSRTSTYVSTMPGGAETTITTMEVVTGEAAAAPTPTNDGSGGQLQTGNPAPYLAAPIYQVMAGAVAIGGVFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V877</accession>
    <name>A0ABR1V877_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
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            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_066817244.1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
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            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
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        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
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        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="228" mass="26027" checksum="9907A7EF2838FAFA" modified="2025-10-08" version="1">MDYGRRSDRYDDYSPPRHHRGPGAVESTYVRDGGREYQQYGHRRRASDGERSTYRQEHYELPRPPPKGRHYDYEEIYEVERRRRPAHSQRRPSYSTGPVTRSRNISTSTSYSDERDRQHHPSRRHSQPNHHHERKKSSSGKDPFGLDLNWKQAAEAAAGAAAAEAWRSRGNPDKMRRVATAAAGAVAVDLALGRGAGDEKNKRHAVESAIGGLVFDRMVNGSRDKVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V926</accession>
    <name>A0ABR1V926_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Matrin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_013517</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663523.1">
        <property type="nucleotide sequence ID" value="XM_066817831.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050891"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051421">
        <property type="entry name" value="RNA_Proc_DNA_Dmg_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031774">
        <property type="entry name" value="SF3A3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024598">
        <property type="entry name" value="SF3a60/Prp9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021966">
        <property type="entry name" value="SF3a60_bindingd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786:SF2">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786">
        <property type="entry name" value="SPLICING FACTOR SF3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16837">
        <property type="entry name" value="SF3A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12108">
        <property type="entry name" value="SF3a60_bindingd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11931">
        <property type="entry name" value="SF3a60_Prp9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="9">
        <location>
            <begin position="414"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="280"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="327"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="373"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="509" mass="58715" checksum="95329C670914F3BF" modified="2025-10-08" version="1">MLLEEQRFLHEDLERLEQGIADRIGEEPKNIRDRLTRDHQVSEFLDRIASQSSKLLEIYRDADGARSKEIQQIGSGDPMEEFHKQLAEIKSFHTRYPNEPVENLERAYRPRKPTEAEAAQPSVVDSLFTGEEAFGRFFDLHTCHEAYLNLHNAKRLSYLQYLDVFDNFSPGAGGLKRGEKLTDQYFRYAGLVSQYLEDFMRRTRPLENVDKVLADFDREFDEAWEKDDVEGWKSETVAVSTSGVSRQLSSAEAVYCEDCEKEFKNENVYKGHLSGKKHVRAAADRKKRIEENTEMGGTSEGDNRGGVSATRLKERAIAEREHRVKRLASAMSTERSDTRVNVERKQGMTERERQQELENLFSATVETQPAEQGEGEEGEDDDDRFYNPLKLPLAWDGKPIPYWLYKLHGLGVEFSCEVCGNFVYMGRRAFDKHFNEARHIYGLKCLGITNTSLFRDITGIDEALRLWEKIQKDKKKDKIDDGAMVQMEDADGNVMPEKVYYDLQKQGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGW8</accession>
    <name>A0ABR1VGW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hippurate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664265.1">
        <property type="nucleotide sequence ID" value="XM_066814975.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048035"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014:SF63">
        <property type="entry name" value="METALLOPEPTIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PEPTIDASE M20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="2">
        <location>
            <begin position="210"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="467" mass="50367" checksum="F282AC53B128BE3D" modified="2025-10-08" version="1">MASISSIVAQHRPDLGPLQDLYKHFHEHPELSNQEKETAAAIAAELRNISPDFVIKTGIGGHGLAAILRNNGDGEGGPTVLLRADIDALPVLERTGLPYASTRRMRDVLDGVEKPVMHACGHDMHIASLLGAARTLVSSRALWRGTLVLVFQPAEERGTGAQAMVDDGLYSPARHAVPVPDVVLGAHVTGAARTGVIGTRRGLMATSADSLRVTLHGRGGHASMPHAAVDPVLMAASAILKLQTIVSRETDPADSAVVTVASVHAGDAENIIADEARLSVESRAVNQRTRERTLRRIREIVRAECLGAQATREPTFETTRAFPLTINDEEVTARVEETFAAHFGEGKGKEKPTTIVNQKGADEKEQGEEKGMMRHECCRYDRDIPAVRRQRGLQYPGDGGGEAVLLLHVRGRGRGGVGPGPRLRGRWRRASHRTTRRSFAPAVMPTLRVGLDGYAAAALTFLEKKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHS2</accession>
    <name>A0ABR1VHS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010951</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664556.1">
        <property type="nucleotide sequence ID" value="XM_066815266.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048326"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07090">
        <property type="entry name" value="ALDH_F9_TMBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009725">
        <property type="entry name" value="PRK13252.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8070748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="500" mass="53476" checksum="391BACC2B2A8876C" modified="2025-10-08" version="1">MVRREQDRHTFYAGKPQPSADSPGTFKTINPSTAEPVCTIHTSSPRAIDAAVQSAQSAFPSWSATPPVERARVLQRAVALLRQRNDELARVETLDTGKPFSETSAVDIVTGADVLEYFANLVAGGGLNGEAFRLRPSAMVYTTKEPLGVCAGIGAWNYPIQIALWKSAPCLAAGNCMVYKPSEYTPMHAQYLASIYREAGLPEGVFNVVYGAGEVGGQLTAHPAIAKVSFTGQVSTGKKVAGAAAGGMKYVTMELGGKSPVIVLPDADVDQAADGALLANFYSTGQVCTNGTRVFVPRHMKQNFEKAVLSKIQHVRAGDLFDAATNFGPLSSKPHYDKVVSYVRRGIEQDKATLLCGGVSQPSGLPSGLKNGYWIEPTVFTDCTDDMTIVKEEIFGPVMSILYYDAVDEAVRRANATELGLAAGVFGKDINECHRVISQLEAGITWINTWGESPAEMAVGGWKSSGVGVENGRRGLEAWVRNKSTLVEMGGEVPTVFSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI77</accession>
    <name>A0ABR1VI77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664742.1">
        <property type="nucleotide sequence ID" value="XM_066815452.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048512"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045359599" evidence="2">
        <location>
            <begin position="18"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="292" mass="31308" checksum="2CF75EFB2DA9659A" modified="2025-10-08" version="1">MKLFAIIISAFLLAVQAQGSYRYGENDTTVIVTSTTTVAGLSASTPTSSGKTTVSDHTATEPHVPFRHTSHLPMSHLHLTSSWSFNGTQTRPIPTGGSVTSYHGYSTSTHGSPMPSATSHSSHTYSTITAITLSTDGPNIPEGTVSDNGDQPTNKGGLMPVPIVHPTTSFSRCPESTKHSTAAPKHTGSSEAGKPITFSGFTITLPWQTITLEPTTWTLDLPSIPTTFVPLPSEPAADGPHHEPPPPRWRSTSLIPRPLSLSRRLRRRLRLARHPLHRAPPPGQHPPFQAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIG0</accession>
    <name>A0ABR1VIG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664812.1">
        <property type="nucleotide sequence ID" value="XM_066815522.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048582"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="456" mass="52054" checksum="53343B686617ECE1" modified="2025-10-08" version="1">MIYSQPALTVIRLELDPRLTEIQPPSVFDELWKATLSSLSNDFHGIKDKFPAAVGKPFMMFWGTSESDKNIYFVLIFWPSVAARDEFRDSALGMYMMVPCFKEVPSFKPAPKGLWEFWFGDVDADEVEEVERLAETLTAHIGIVKKRSSLNSQENPTFRAHQRPLIVERASRQTTQQVFIRVQLSRTVANSEDEPLEDPGWEIHKVALRLLFSERAPGHVGPMAILSTTPTASLFHAKWPQYGKSQSPPGYVCPKSTDFHPMKMKETKDHHFNHKLKIHSDFLLGSEDTVLYPGLLGPEKPGSQGPCKIDTFLVEYTDSSLSSLPATTLLQEKLSEIMERATGINQVQWGQTTHDSSPLKYMIMIVWSDFDNAVTQTVCDMILEGENVKAELISWKIRSNEALDYDGKLVELIRFRIPAPQPNMNSQVSQELVDRSRQSAVRNRRLFQYLLDWFRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VII1</accession>
    <name>A0ABR1VII1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664755.1">
        <property type="nucleotide sequence ID" value="XM_066815465.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048525"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="589" mass="66541" checksum="0FA0218BF83AF938" modified="2025-10-08" version="1">MARHPISYPMLQPISVTALQESNLLRSVKSNRPTELSFQRRMAMLKPSSSIGLQDSLATGELFNIDADSAVKLYRIHGAPEDPLPISRDYCDDRLSGLHISAWTTVQISNELAARIVSLYLKTDHPMLGTFDPDLFVSDLVTQQKRFCSSLLVNALLYWGSQMYSAIDKEVQKYVRLFCTEAERLWSEAKHTDTLLNMAGAQLLSLASMGHGKDHACLKYLTEAVNMGVRLKLFGRTDAIGEDTQRKMSVDDQSATSFAAWGIFNWSVLTTIFYRQPGISYPDSPPVCLIPGNIQSGSSPPADIDSSSEETSVSPKRSLPAYMGTTFTFICQLWRIVHELTLTYYNEKYKTKPPNLDFAEMKYRELLAWMQNLPTELARGEDNPHHVLVFHIWVHAVVLDLFRPFVNDPEMRHAKLKTFSARHGSPQTAFDASVEQLKHLIIDYRNNYESSACTILWHTALMYVANAVLVSKDTDWRVYFLLCIYGYESLNRPFRVSEAIGTSLLTMTLRNSDITIEEARSLLLELKERGLAHLPSEGTIRATFMGDLELAMSDPEAARVENLANNFEDMVLFREFVNDGSIEDVSMVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VII6</accession>
    <name>A0ABR1VII6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WW domain binding protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664842.1">
        <property type="nucleotide sequence ID" value="XM_066815552.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048612"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019007">
        <property type="entry name" value="Wbp11/ELF5/Saf1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09429">
        <property type="entry name" value="Wbp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wbp11/ELF5/Saf1 N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="275" mass="30370" checksum="D7A940E5A1FA4E13" modified="2025-10-08" version="1">MPKERNFNPVQAQRKADKAKEVKKGKQEATARRNEKLAKRNPERLQKQVDDLKQITASGRKLTKHEESVLESLEADLKAVKKAREALGDKAPTFGRGGPRDGQGHGGVLGKRRRDFDEASSSDSDVPDDVKSIPMPRDTPPPIPKEIMDQWYAKRRAKRTNPNETPLGGDKERRAPGQTQTQAQATPTPPVEVKAVYEAKPVIRDLRKEAVSAFMPTAVRMKIDKGKGQGGLLEPEEADRLEAEGYLKVAADPGSTNKPNPLTATVEDVEDDDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIW5</accession>
    <name>A0ABR1VIW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664984.1">
        <property type="nucleotide sequence ID" value="XM_066815694.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048754"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="554"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="600" mass="67461" checksum="8DDB8438B8B53535" modified="2025-10-08" version="1">MCVFMILYPQLRKANTGWKQASFTESRYSQEMDEVHVAVRLNLEERLTTLTRASSINLVANRDADFTPLQIDSLRRFNSFLRNNYTELFPTIARPILSVFLVLLRSTVANSSATSEARICLSGLRSQYEVTRFHQVLTQSHCRVHCDPLKLCYSTSLIRLVGADRPHTTFEIRGGSVGSTLVSKTTVDDNTQTATATIGGFIEVEGRSYAVTIVHDEKEYHQGSNTIPNTFVATENKSDAELPLVVDSWANKDPPAGNDDTLLWCPSKERFVRFGEWALIPVPWPDKRPNSYVLPQSDSRAELRTKYWGFRVLGGQGVEQYPYRFGDSDISRLCLHCPLSDFMQQARQHIWHDAMISIPLPFATFLDLGQHDLYRRESFIKQAISTKSLEASVKDAVARQLFSSVEHGKANEVERLVKKMKLDHGALKKLFEDLLKLDSSRTLGYKDDVLGLAQSIVGDGMNLDIESQNASRSVGSSILHEVTSTPEPRLSKDSEEDMTKNQPSSTASLPALMTLGNSELGVESRNSDTHQSSQSFNQYTMGAQESASGSLVYRSRPSSSRRASPRNNIDLDEDFTLQARRGRRSNEYEMGKRLCSKIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIZ5</accession>
    <name>A0ABR1VIZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665015.1">
        <property type="nucleotide sequence ID" value="XM_066815725.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048785"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF80">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="5">
        <location>
            <begin position="59"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8071207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="226" mass="25161" checksum="BF8A6B4AE97D1ED0" modified="2025-10-08" version="1">MADSEAAEMRNADYWDGRYSNEDDPATKEWHVGPDKLEGYLEENIYPRWPQGTTPKIVQLGSGASSVPFEMYSRGYTDQTCVEFSAAVIAQMAPKNPAIRWLPHDVRNMPEIESNSFDFAFDKATFYALCAWGPTHLLKSIPPVIVEDTAAYSREVFRILKPGGVFVCINIFEPRYVNHLLKVEGTNWTDLHTPMALTPAGWAVTRAYGLVKGPIEPTDSEAAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJM4</accession>
    <name>A0ABR1VJM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="10">PPIase</shortName>
            <ecNumber evidence="10">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_011618</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665223.1">
        <property type="nucleotide sequence ID" value="XM_066815933.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048993"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01921">
        <property type="entry name" value="cyclophilin_RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12235">
        <property type="entry name" value="RRM_PPIL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035542">
        <property type="entry name" value="CRIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035538">
        <property type="entry name" value="Cyclophilin_PPIL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="12">
        <location>
            <begin position="6"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="13">
        <location>
            <begin position="249"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="381"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="412"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="452"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8071415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="502" mass="55945" checksum="6E58DDAF3F56D3C3" modified="2025-10-08" version="1">MSVLLETSLGDIVIDLLVDYAPKECENFLKLAKIKYYNFSPVHSVQQDFSFQSGDPLGPTAPSSDGGSSIWGVLSGSAAKKTFPATLHPKLKHAERGTVSMATTPHPTNPEVRLAASQFIVTLGDNTDYLDGRASIFAKVVEGFDVLEKVNAAITDKEGHPLVDIRIKHTVILDDPYPDPAGLREPSASPPPTKAQLATVRIADDADLNEEVDEEAAEKKRREAEARAQALTLEMMGDLPFADVKPPENILFVCKLNPVTTDADLELIFSRFGKILSCEVIRDKKTGDSLQYAFIEYDEKTAAEAAYSKMQSVLIDDRRIHVDFSQSVSKLSEEWRSGEVAKRRRTGGGGGWGGVEGLEKWRKYRHEDRVADRNDKYGMVYSDEEMRGRHGRQGERAERDDTGAGAGGESSSRADNERPRRQDGGRGRGGGGSDARRRSRSRSPRGGGYRGNGDRGRDRRDGDRGRDRRYDGQRRRDDRYDGKDRRDRSRDRGSSYNDYRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJP4</accession>
    <name>A0ABR1VJP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RelA/SpoT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664915.1">
        <property type="nucleotide sequence ID" value="XM_066815625.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048685"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41773">
        <property type="entry name" value="GTP PYROPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41773:SF1">
        <property type="entry name" value="RELA_SPOT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RelA/SpoT" evidence="1">
        <location>
            <begin position="97"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="763" mass="86620" checksum="54BF1942D006D212" modified="2025-10-08" version="1">MPLSDKLDDSKLEEFKATYRDNVSVIEDHVNRILHILNHDKTGLRSRQIMHKPITSRMKTLDSAVGSLKRRHKIRLQHATLKTRLEGHGESWTEYWTRRHQVHRIDDVGTFTGVDQMYEALHDIGGIRICVYFPSDAEKVVAFLREHSEIEVERVVLWGQGVAPEIQQLEQLLVDLGTGRDMDHGGPEPGRPKYIVKESPNYRATHVVVKHLGSSSDRPRKRPGVVEIQIANVMMDLCAQLDHDIVYKPGAQMTEEEEEDRFVLGGVLRTFSSIAKAGESALAQLEKYRAYKTEQRSKEQRRPADNAYEFGSFLFSACKAKSLNLSAISHLRTGSWKHLHHLFDVLRATDEHHKLKLHTLLESFLNRNGKSNGAITCILPVHLLREVYEVAEKCPSIQKGSASDVQHIRALAMQAVRCLNLACYLGVEQGFMAAIDKSLPPIDQRPSLTDLLDAVHPHHPRLNTFKQEQITNFCRTVLNQAALDVGPYKHHLLISTLLELPILLSEIGYTGVEARPNTGHGEEDFSIVPRTLCQLLADTEGIHWIPELLDGAHRLIRTKSAILWAQQNSMDDLSVGISPKHLASLAQQYPADPSLYLSRTASMQDELRRIYLEIRKQVTDWNVPHYEFDAKCHPRPYPGYFKPRKPDPKDKLPGWVYVGGHHHGQLEWDVKKINPRVVEPDPEIVLHHGTTSNDGFQELIQATERMETGGQLTHVANYTTEAKDNITEFSLTLSGGRFCLLLCQDKFILKREEDGDEQGDSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VK16</accession>
    <name>A0ABR1VK16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665050.1">
        <property type="nucleotide sequence ID" value="XM_066815760.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048820"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="141" mass="14614" checksum="934C7E72AB912F5E" modified="2025-10-08" version="1">MKIFGLHSADDCSAYSSPSGTATSCPLAGETPAPARPGTGYRPAAAPRRGTPLDGRELALVQDHILVGPAVGANRRHAPAQALAELLLEHPDEAAPAPAPALRLRLPALLRVGVDPVGRGEQVHRGVAEPALRAHEARLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLG7</accession>
    <name>A0ABR1VLG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664944.1">
        <property type="nucleotide sequence ID" value="XM_066815654.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048714"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="254" mass="28362" checksum="ECB760329969C495" modified="2025-10-08" version="1">MAVRKHGLDGRTSNPVPPLPRHPIRPAPLLKPPAPWGLAVYRADYRDDAAWRRMQEALLAHAAGALAATITTDADDAHHLLQRSHTAFLSDPVPPAAARRSDVRAHFARWAAAELRRNWYVTPDSPLPDLERARGAGAGSPGYRAGARYNFYLEVDAQSLRSLDSETPAVKIVRKDWSKEGWDESSSSSPSGVEAGYDSYLLPLKDYVAACRILLDPKKWYSRPYDESRNIIRRVKLRTFGRIAYRSILLATDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLQ4</accession>
    <name>A0ABR1VLQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011429</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665034.1">
        <property type="nucleotide sequence ID" value="XM_066815744.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048804"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="146" mass="15438" checksum="E1A6C685BBAC692C" modified="2025-10-08" version="1">MFTTHSPICRRRRVFCLGAQVEVIVLFNSTSSLDPNAFLTRPEVERKLVVSIPAGLVRAFFLGGPESSSRRFSSFFTAGSGDEATTISASVAAAEFESGCAGFGLPAVFLAANLASSNFFELSSLCDWGDAPDASDGRSLWGANVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLT6</accession>
    <name>A0ABR1VLT6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664626.1">
        <property type="nucleotide sequence ID" value="XM_066815336.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048396"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="382" mass="43209" checksum="D1424FA93388DC17" modified="2025-10-08" version="1">MLADQGLRKKARKAALVEKPTPASGRSFSSLAGDGHNSDAEPPSLSAARGTFLKDARAINEENHPTLYDKASRKANAVDMAPETRAPSPTDKLLKSSRLANTGSNKSSRHALDDTLQGLVDEDEDEWLCGGGQPREKNAPHSDITTRKTRITSPSSSDEPLVAQPVSNTNSRAGKGLRKASSESSGRPHPTLAKLSRKNVRSREIIDFPSDDEFESLSTFLANPARGQGHEQQHAHDDFVPQEGSVIQDNKSQRNTKAAQKRQEELDKAKKRQAEQEAAAEEARKRDEARQREEARQQEEARQREEARQREEARQREEARQREEARQREEIKQREEARRLEEARLREEVERREREVERREREIERREREGEGEGGEATTRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTD3</accession>
    <name>A0ABR1VTD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665417.1">
        <property type="nucleotide sequence ID" value="XM_066813455.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046515"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="293" mass="32618" checksum="805D33B098408681" modified="2025-10-08" version="1">MATESTTQILAVKEVSGYGYLIRASFNGLISRLERPRRLRPLIPPGPYPADLKCIRLRRPDERDNIDPKDVTDYPIAEPLDHVLTGVGNPTNLPTYDYNRLIQLEKIRSPRYEHRISEDRLCRVRGVNGVPSMVMKIAELPDKWPVQIASTSSSTVPGAPPIPFMLDIASPHPPSVTPTLAERDMTREIAMHQQVAAALGARGDNRGLVPAFYGLVTERGRGVVGFLSEYIEGSRTMYSLFREAADRGSRTGRCPRRSGRRAVRRCGRSMWRASCTAMYMLATSCAAVMAQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUZ4</accession>
    <name>A0ABR1VUZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Signal peptide peptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009737</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666014.1">
        <property type="nucleotide sequence ID" value="XM_066814052.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047112"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF23">
        <property type="entry name" value="MINOR HISTOCOMPATIBILITY ANTIGEN H13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="519"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="519"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="574" mass="64199" checksum="600D4DBB493649DB" modified="2025-10-08" version="1">MANATSPGAAEGMSFTGNLTLAESISQWPAAVWNNRDFLLLEARIVGSAMACIYVSSQAALRRPPSARLPKKKKGKHGKKSDESSEDEYVQGLLLSDAIMFPILAGMVLVGLYYLIKWLEDPAILNKILGVYFSVMSLASMGKLFSDGLQLIFSMVFPEVWRAHDGSLFHFDNHKRSQYRISESGEHIYEAGIQSPLPGNYLSKMKQPGLSSSLWVFRLIMQEQWKVNFTFLPFVEESFHVKFLDILGVVLAVVANIIYHTTKSVMLSNIMGYAFSYAGIIMMSPTTFTTGSCVLFGLFFYDIYMVFYTPYMVTVATKLDVPIKLVFEGPQKASMLGLGDIVVPGMFVGLCLRFDHFLYYHRQKKHVPIDLKTTDENSGQVVTSTQTQPMVVRPDYVNPKSQWGNWFWTTGLGRFFWQSTNATTPALKAANFPKTYFHAAMTGYLLGMMVTLMMLLVFKHAQPALLYLVPGVVFAVWITGLFRGELHEMWIYTEDGSLDKEDVVVEVDGDGNVIKQAEDAHEKKGAETKALEKARSDKTAEKEDATAAEGEEPEPTTVFAFTIQAPASLSRRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVD4</accession>
    <name>A0ABR1VVD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Something about silencing protein 4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666148.1">
        <property type="nucleotide sequence ID" value="XM_066814186.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047246"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038988">
        <property type="entry name" value="Sas4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029184">
        <property type="entry name" value="Sas4_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38422">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38422:SF1">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15460">
        <property type="entry name" value="SAS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Something about silencing protein 4" evidence="2">
        <location>
            <begin position="311"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="579" mass="65431" checksum="03FB763E626EC6D7" modified="2025-10-08" version="1">MATINRRSTRHASEAQQRQERSSGRSAAKRGRSDITTTAPTAGSSNSIATTTSTRSSHPNLPQQTHPARMKRPLEIIDTNLDHPKSKRARIAVEILSRSIPPGISPPKSIAVRPQSTTPTAAKPATVATTQRKLHQQRQQQTPLLPPPRNLRPLLPPLPINRLQPNATDVAQQPKEQGGRKLRSQEQTRFKSELSAYFPDYDEVIGNDPKEQHVLNVDTPIVVFDSNTTPDAQAQGGRILPSRHAAHHDAGPASHTAKSDSQLAHSRSTFASPNDDFPVKSYGDELYTNLFDSEIVSNALVQDNDNDDDEDPLADEHYEPAHRRAERLEKSIRNTERGRAQHERDQIVRLLSDLQGHDWLRTMGVNGVTESRKKTFEPARDHFIHGCQAILEKFRHWTQEEKRLKLERERALAEREAGSEGSEEPSESGEEEDEAEASEQDDEMISADSDREIPDSVSDGDPPDHSDVDASIAKQLHEEALARAKYTAPTGARRSRADPPPHHSDFWAPPREFTSFFSKRHERDAAMRRSRRGRIVMAWGHPIPDFEEDEFDLSEEYRDEDYMKSRARRKRRDKRGRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVW2</accession>
    <name>A0ABR1VVW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GA4 desaturase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010049</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666326.1">
        <property type="nucleotide sequence ID" value="XM_066814364.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047424"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="36149" checksum="31D498AF4C0E35A0" modified="2025-10-08" version="1">MASSNPTCGVFTFVEPDLSVSAHDRPMFAAPDTKTSVEEKLVLHDFRTATDVARGAEGLDVQGFTFINHKSALDTELLLNGTNIEVVEETYAQEALNLALEITGAKRGIVHNVVFRRRLSPGEPDLSSLFPKGDSSAPEKAPGRKILVPSPQGPARQMHIDLSLEGLEQTLRYCRRDIAEFAAPVLAAQDRRAAGDKDVKVPRFAAYSIWRALRTVKRDPIAVCDWRSLDKKSDLVPTENRKPSEINACGYYIGGAMGGLPPKNPQNQRWYWMPNQTPEEVTIIKFADSASVNPAVAAGCLHGSPEVPGTEEEETRCSVETRVYLFWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWB4</accession>
    <name>A0ABR1VWB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isoflavone reductase like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666474.1">
        <property type="nucleotide sequence ID" value="XM_066814512.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047572"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="274" mass="30085" checksum="FCA0A6AAE8560FF3" modified="2025-10-08" version="1" fragment="single">MLVLIAGITGTCGQHLARAAMAADHRVRGLTHDSDSLEPGIEERLEGFVKMTHAYDIQALVEACQDVDAVMCAYSWEPQLIVEGQLLLLRAAERAGVKIFHACSWNYDQLGDHEAYDSYIMFCNHARISSTIRPIYGFTGLTPQYTLTHPSAGMSEHENLALNYFGNGDEQDITAADLAAYSIAAISDPHAADGGLYHVIIFHEPDANTYEEVVRGVKINWKHHGGGGSSTAHNEHHSTIRRAARAKAGRVFTLTNRFENGCMSISKSDDERGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWM4</accession>
    <name>A0ABR1VWM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Membrane-associating domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010292</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666569.1">
        <property type="nucleotide sequence ID" value="XM_066814607.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047667"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451">
        <property type="entry name" value="MARVEL DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF1">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="8"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="161" mass="17401" checksum="1295E8BEF81E86FF" modified="2025-10-08" version="1">MALGFLPIVHAVAAVFTIIELGLTGYLVSAYTGYWGWGGYWGNSPDRVNFMLFNSIWSLLVLAYVGIVPIYLTGWFHKLAALVLNALTCLFWFAGSIALAVVVGVPHCNGQGLCSSLQAAIAFGFFLWAIFTFLTVLDGLESLRSRGHNVPHSKPSAYPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX86</accession>
    <name>A0ABR1VX86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">4-dimethylallyltryptophan N-methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.261</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_010470</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine = 4-(3-methylbut-2-enyl)-L-abrine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:34435"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58209"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:67248"/>
            <dbReference type="EC" id="2.1.1.261"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis; ergot alkaloid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.261" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666747.1">
        <property type="nucleotide sequence ID" value="XM_066814785.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047845"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051128">
        <property type="entry name" value="EgtD_Methyltrsf_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017805">
        <property type="entry name" value="SAM_MeTrfase_EasF-type_put"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03439">
        <property type="entry name" value="methyl_EasF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397:SF1">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="10">
        <location>
            <begin position="64"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8075807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="383" mass="43195" checksum="A9EB1F9859610400" modified="2025-10-08" version="1">MLVELSVAPNPLILDANPGGGRPEKIPSETQINVSVQPNTDEERYDIDIIDIRDGQQSFDLAPAIRSGLQHRNEHGHRTLPSLLLWNERGLKLFEEITYTPEYYLTNTEIALLEAHSREIARQIEPGTILLELGSGNLRKIRILLQALEAQGRRVGYYALDLDRRELERTLGQLRTDLDGRGFFRHVRCHGLHGTYDDGQVWIARPENARRPRCVLLSLGSTLGSFAPAEAAARLLPPSSSRIILGLDGCTDAGRVFAAYNDRAGTNRAFILNALDGANAHLGYEAFLASDWTVRGEWDAGAKRHVQYLVPLRDAQVTFLRARQHQHHQSVTVKANEKLELTSSYKFDDADRERLWTESGLRATKQFLSKDGSYEERELLLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXZ5</accession>
    <name>A0ABR1VXZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665658.1">
        <property type="nucleotide sequence ID" value="XM_066813696.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046756"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF7">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="69"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="286" mass="31805" checksum="0D1A3FD3FDB37846" modified="2025-10-08" version="1">MFSTSKRYEAPPSRSSSKTHKVSKSSSSFNKSHAGVSKSRHEPRRRPTTATMSSAHDASMSPASTLTPSIVTLVIGRDQRIFAAHEDVLCASPWFQRHLSDMYLDPESANNKRIFLADEEPEIFSSILEYMYKGDYYPRLVHNKKRNSWEIEQLESDGRGESTVYHHATDGDLLKDTVIYCTADRYGLEELKRVALRKQGLQSGIQCSTILASARYAYANTPDTDSKLRAHYLALIIRAAARSSVAARCSLKCITAALSSSLIYSSPYATMSMTSPLPPSNPLLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZR4</accession>
    <name>A0ABR1VZR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666364.1">
        <property type="nucleotide sequence ID" value="XM_066814402.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047462"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF13">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="29"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="349" mass="37618" checksum="5375B40ACF03D376" modified="2025-10-08" version="1">MRFQGTQLAAGLLSWSSVSTPGQPRGGGIPHLHQIIGGNAFNASMDPVKLDIPGTATCTTCQFADDFSNYWTAVLFFRARNGTYHRVPQKGNVFFEQANGGMTVYYTPTLNGRGKVTAFKPGFRMIVGDPMERTAAGAAKYRQLTYTCLQNSMTRTGETKNLPPKPCPAGIMANIRFPTYVFPATEAPLPPHPLIITKPAGTASTSTAPTTRATSPTRPAAPSRAAGPCPSTHPVKIPQLFYEVIWDTSKFNNAADWPADGSQPFVWSYGDATGYGTHGDYVFGWKGDALQRAMDQNCQNDKCNGLGSQSLQQGNKCTVKTTVDESIDGWLDELPGGMKVTDASGKVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZX8</accession>
    <name>A0ABR1VZX8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666816.1">
        <property type="nucleotide sequence ID" value="XM_066814854.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047914"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="347" mass="38014" checksum="89E2A910EE7BCB7E" modified="2025-10-08" version="1">MYDHLGIRYHAKRFLFAFSDVTARLYGGRNDEEKSPSLSGADSPPYFIHSSNNHRILPVRPPGAHAAGHLLEVVFVLACYAWYSLCCFLADPRAGESYGAYLKRMRVPQRFVRRYMVPILSSVATCSHEELLAFPASDLTGYQRGIFATDHFVVSHGVQDVVTVLSESQDIRLSSEVLLVESCGSRVRLVWTQGPGEDVVEEVFDRVVLAIDPCAVAKVYAPLRSVVSRMPTRIVESAVLQGADKSTKLRVAERSFKQNDTAGVDALVADTLLLRSELTGSGCTEALHTVNCGAVVATSISGGFGELNVLHRAAFWRVLRTPESQEIVNSVMQKGQKGTRLTVPGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7G2</accession>
    <name>A0ABR1W7G2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007241</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666898.1">
        <property type="nucleotide sequence ID" value="XM_066811556.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044616"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013700">
        <property type="entry name" value="AflR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF31">
        <property type="entry name" value="MONODICTYPHENONE CLUSTER TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08493">
        <property type="entry name" value="AflR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047324971" description="Zn(2)-C6 fungal-type domain-containing protein" evidence="7">
        <location>
            <begin position="25"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="121"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8079423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="428" mass="47519" checksum="C5689E3BC0AFABBF" modified="2025-10-08" version="1">MPAHVLFSFTCFVLSRFYGGLVVADPQLVPLRSLGTATSHVVQPSLGRKMSPHSIEVPITPSSPSILGQTTPASAINGDSQRRVRLRQACDACTTAKVKCDKGRPACQRCLDIDDFCQYSPSRRHGRRPRRARTSPRETPSSQPPQPLREVGMVEYSTMPSFADLFPVSTNIPMDMAAIPDFTFDNELDLSSLHVGSNIRNSHCAHSQDSTSSLNNAHIPPVQQQPSEKGGADMGLELVSRQDHKQEDGHASECEARALGVLKSLQYSPVLHDASPTAGYWVDSMERLLSTNKTALDELPRLLECRCVDSRHVALLHLTILSKIVSWYEVAVTAEYHSKRIVLKPMKIQFSVLDLDSDDYDMLHRAVLCRELQRAGGAIRKLEVRLATSDTPECAQNSAWGRLIIQAIRDELERCVLEMEKRPARNCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7T1</accession>
    <name>A0ABR1W7T1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007358</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the actin-binding proteins ADF family. GMF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667015.1">
        <property type="nucleotide sequence ID" value="XM_066811673.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044733"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11283">
        <property type="entry name" value="ADF_GMF-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011171">
        <property type="entry name" value="GMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249:SF2">
        <property type="entry name" value="GLIA MATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249">
        <property type="entry name" value="GLIAL FACTOR NATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001788">
        <property type="entry name" value="GMF-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="3">
        <location>
            <begin position="8"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="156" mass="17935" checksum="AE97FDAD3795A7D6" modified="2025-10-08" version="1">MVSPAEARLYTFSQETKDHLRKFRLGTSRANDPQAVISVGHKQLIQFDPDMIDRKTHEIRQDEDKMVYKSLEEVGDELPDNSPRFVLLSYPLTLPSGRLSVPYVMLYYLPITCNNELRMIYAGAKELMRNTAEVGKIFDIESADDLEEIPKKLAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8N6</accession>
    <name>A0ABR1W8N6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adaptin ear-binding coat-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667335.1">
        <property type="nucleotide sequence ID" value="XM_066811993.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045053"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13228">
        <property type="entry name" value="PHear_NECAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012466">
        <property type="entry name" value="NECAP_PHear"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847">
        <property type="entry name" value="ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847:SF9">
        <property type="entry name" value="NECAP-LIKE PROTEIN CG9132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07933">
        <property type="entry name" value="DUF1681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NECAP PHear" evidence="2">
        <location>
            <begin position="17"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="283" mass="29796" checksum="08BB815A8D872D6E" modified="2025-10-08" version="1">MEGIDPITGRPLASDAIQRVLFIAPKVHVYNIPPMVPGKGHVAAGWTADGNKRQIFTARLRVLETAETVPAGGSGGNGGEEEEESEKVKTDVVLEDASNGQLFAAAPYTTAAVVEPVSDSSRFFAVRVQDEAGRKASLGIGFEERSDAFDFSVALQEARKSLGWEQPQNNATGGGPKKASEKKEEEKRDYSLKEGETITVNLPGRFGRRRPDAGESSASSSEGSAPLASFSLPPPPSSASSTRAPGILPPPPSAQSSKVHTHQRGKPSAADLGFDDGQNGEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W961</accession>
    <name>A0ABR1W961_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667422.1">
        <property type="nucleotide sequence ID" value="XM_066812080.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045140"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="187" mass="21508" checksum="4E29B3DD6E73F1EC" modified="2025-10-08" version="1">MDMLWSGFRRSPNKGDMSLFRRLSPRLLELAKCMYGEDRVGGVRFGRIKETAYILVILIKEPAGAEGPASDAIMELNARFYEVLKDGQAGEAEAIEQCYQRRRRYRRHCEALRGGQEGWKEGREGEKGEDGRENDGEEDSDEQYDRWIELQQEGKSLVDLFEVQVHHPISGRLLVGPVEKQKNFTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9A8</accession>
    <name>A0ABR1W9A8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007918</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667575.1">
        <property type="nucleotide sequence ID" value="XM_066812233.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045293"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="53667" checksum="6B3618BBFA701DB8" modified="2025-10-08" version="1">MHKRRSHHKSRNGCYSCKQKHVKCDEQGPPCTTCVLRDAECIYPTPEELEEARPRKQTKSSTVRPKTQTPKLVKKESLPSCLAPAAAPKLLSSPSQPPVSGEPIYDRRLELELMHQWTTKTWMGFYEIPEDQRYLQEELPRTALGEGYLLNGILAIAATDLAHQAAGLVSSKYVCAALGYSNRASIQFRQQLSKLAATNNHHVSYHGGIIVEKRNFSWINNGVARDDDADSGYNSQQDHHHPSSLLERLDVFFKLLLGTYNTLLTNIQWTMDNPTNIRAAVEKLMKEPLAIDLVSFETRLAMERLTRVSQQFRTNFPIYSNNGDAAAAPPQPALGHLCSEVPAYRLIISQTKLSFVVEALNLSQGLCLSLITTTGLDFLNLVKAMDPMALFVLIHLGVLFYRLFGKWDGFGWTMGNIVQELVKELSGILEATPIYQLQEGRDGIVWCQQQTGLLPIPLEAAAGTIVIPGMTLDQELNRGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9G0</accession>
    <name>A0ABR1W9G0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007978</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667635.1">
        <property type="nucleotide sequence ID" value="XM_066812293.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045353"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037548">
        <property type="entry name" value="Bqt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38044">
        <property type="entry name" value="BOUQUET FORMATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38044:SF1">
        <property type="entry name" value="BOUQUET FORMATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0183">Conidiation</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="HTH APSES-type" evidence="6">
        <location>
            <begin position="61"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="184"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="334"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="415" mass="45119" checksum="C0252F80550E934F" modified="2025-10-08" version="1">MDASRQLPKTHNPLMVENVPPFTDLVGRRRLGQTQLTPKMVQATSTADLDASNLGVFDYAHLRAPLPKGIVSGIFKSSPNSYFLMRRSQDGFVSATGMFKATFPYAEAIEEENERKYIKSLVTTSHEETAGNVWIPPEQALSLATEYRITPWIRALLDPAEIPVTTTSESSSKKIQAPPKFDPILASQNTLAPPTPSSLRSTRARRSASPAKKRAIASPRKRSTKVTAAQSTIADQFASEKINGVTAENANEDAPSSTAAEEVQIEQVETEPPVVLAPVEEEPRVQVKVDQDVKVFKGVEATHTAVEIGLPTGNEPPSAEEAARMIEEARAMVQAAAQEVEGTDASKNSKRKVEEMAVGNEEDEEGDEDSSSEPRSKKVKTEVELRKTRVRNRALVGISATLAIGAIIPYVMGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAA2</accession>
    <name>A0ABR1WAA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent DNA helicase II subunit 1</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">ATP-dependent DNA helicase II subunit Ku70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">PG997_008211</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ku70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667868.1">
        <property type="nucleotide sequence ID" value="XM_066812526.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045586"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00788">
        <property type="entry name" value="KU70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01458">
        <property type="entry name" value="vWA_ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.970.10">
        <property type="entry name" value="Ku70, bridge and pillars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="DNA_bd_Ku70/Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006165">
        <property type="entry name" value="Ku70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027388">
        <property type="entry name" value="Ku70_bridge/pillars_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047087">
        <property type="entry name" value="KU70_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005160">
        <property type="entry name" value="Ku_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005161">
        <property type="entry name" value="Ku_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00578">
        <property type="entry name" value="ku70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604">
        <property type="entry name" value="KU AUTOANTIGEN DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604:SF2">
        <property type="entry name" value="X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03730">
        <property type="entry name" value="Ku_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03731">
        <property type="entry name" value="Ku_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003033">
        <property type="entry name" value="Ku70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="SAP" evidence="21">
        <location>
            <begin position="606"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="551"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="551"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK8080393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="644" mass="72535" checksum="0B0CE94E5DDFE224" modified="2025-10-08" version="1">MSYHHSQDGQEPEEDEIDEDIYKSQKDALLFAIDVSKTMMKAPPASDDKKADTDSGLTAALKCAYQVMQQRIISNPKDMMGILLFNTEKSKSNDEEEDRGNWNYPHCYVYVPLDVPAAEDVKRLKSLVEDGEDSEEVLVPSKEPANIKDVLFCANQILATKAPNFGSRRVFIITDSDNPHMDDKKMNEAAAVRAKDLYDLGVFITLFPIGQKDSTFDLSKFWNDIIFKDPMAELTDPETVLESKSGNDGLTLLKSLIKNIDSKKTPKRAYFSSMPFEIGPGLTISVKGYNLFQRQAPARSCYVWLDGEKAQIAVGETARTEKDSTRDVEKGELKKAYKFGGEYVYFSPEEQAEVKKFGEKTIKIIGFKDRSLLKFWMAIKKSIFIYPSEEGYVGSTRVFSALWQKLLKSKKVGIAWHIARKNANPQLVAIIPSRSQLDEKSGTPYLPAGLWLYPIPFADDLRVGPELKAVRTTNELTDKMNKITGQLQMPRGLFEPHRYPNPALQWHYKILQALALEEEVPEKPDDATMPKKQGGYLQEWADVANEALAKHQQEKAIKRELDGEDDEEPQPKKRARTTAASKKNDEDGGPATTDAALKKLVNSGDIAKMKVTELKGVLAARSLDTKGRKADLIERLEQWVEENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAB0</accession>
    <name>A0ABR1WAB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">COPI associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007790</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667447.1">
        <property type="nucleotide sequence ID" value="XM_066812105.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045165"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013714">
        <property type="entry name" value="Golgi_TVP15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28128">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28128:SF1">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08507">
        <property type="entry name" value="COPI_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8079972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="130" mass="14208" checksum="44DA827DE95105CA" modified="2025-10-08" version="1">MDFSDSFRIVNLVVAAVMILGGIVQFFNFGVQTLIIGIYEIIFGAAVALLEFQIPPQVSRYASFMFSFIGRGVFYIFMGSILLSSDWFRGLAGSIVAFVGVAYCALEFIPSIEPPANMREADAGWGAEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAR3</accession>
    <name>A0ABR1WAR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_008376</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668033.1">
        <property type="nucleotide sequence ID" value="XM_066812691.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045751"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03273">
        <property type="entry name" value="ABC_SMC2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027120">
        <property type="entry name" value="Smc2_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="14">
        <location>
            <begin position="521"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="403"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="683"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8080558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1188" mass="133800" checksum="BCD4E70C2A8CC7B0" modified="2025-10-08" version="1">MRVTEVIIDGFKSYAVRTVISGWDESFNSITGLNGSGKSNILDAICFVLGITNMTTVRAQNLQDLIYKRGQAGVTKASVTIVFDNRDKNKSPIGFEEYATISVTRQIVLGGTSKYLINGHRAQQQTVQNLFQSVQLNINNPNFLIMQGRITKVLNMKAVEILAMIEEAAGTRMFEDRRDKALKTMSKKEMKLQEITELLRDEIEPKLEKLRTEKRAFLDFQQTQNDLERLTRVVVAHDYVKYQEKLEQSGADLGNKKQRQKDLEDSAARLKGEISHLEEDVKRVKSQRDKELRKGGKAQALEEEVKKHSNELVRLATVLELKNSSKTEEEERKTSVQKNVAELEATLKEKTEAFEEIKAKHDKAKEESVRQSHDAESKEELLQTLQTGVASKEGQESGYQGQLQDARNRAANAATEQEQAKLKITHLEKRIKEEEPRAKKAKEQNAGLLKDIEGLKAQSQKLEAHLAKLGFQPGQEEEMYKQESALQQSIRNLRQEADALKRKVANIDFNYTNPTPDFDRSKVKGLVAQLFTLDKEHTRAGTALEICAGGRLYNVVVDNEVTGTQLLQGGKLRKRVTIIPLNKINSFKASAQTIATAQKIAPGKVDLALELVGYDDEVSAAMGFVFGNTLICEDAETAKRVTFDPNVRMRSITLDGDSYDPSGTLSGGSAPNSSGVLITLQKLNDLSRQLSEAQKSLAQLQGHIQQEKSKLDQARKIKQDLDLKSHEIKLAEEQISGNSSSSIIQEVQNMKENIIQLKADSETAKKRQAEASADVKRIEKDMKDFENNKDSKLVELQASLDELRATLSKNSSALKTLQKEVQNAQLDAEQVSGDLAAAREQLQEVEVAIKSQQQEIEELVKKQSKLQDTHDEVQAALDDERAKLTLFDDELRSLEEAMRSKNSRVAEEGLEMQKLGHTVEKFHKEQQNAVQAVAHMEKEHDWIGDEKDNFGRTGTPYDFKGQNIAECKATLKTLTDRFQGMKKKINPKVMNMIDSVEKKEVALKHMMKTVIRDKRKIEETIISLDDYKKKALLETWEKVNGDFGNIFSELLPGGSFAKLDPARRQDDQRRSRGQGLSWKGVEAESNGIEWWPKLWLTRARRSLVALSLIMALLQFKPAPMYILDEVDAALDLSHTQNIGRLIKTRFKGSQFIVVSLKDGMFQNANRIFRTRFSEGTSMVQALTAADFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB59</accession>
    <name>A0ABR1WB59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Deoxyhypusine hydroxylase</fullName>
            <shortName evidence="10">DOHH</shortName>
            <ecNumber evidence="10">1.14.99.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Deoxyhypusine dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Deoxyhypusine monooxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LIA1</name>
        <name evidence="13" type="ORF">PG997_008535</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[eIF5A protein]-deoxyhypusine + AH2 + O2 = [eIF5A protein]-hypusine + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:14101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10144"/>
            <dbReference type="Rhea" id="RHEA-COMP:12592"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82657"/>
            <dbReference type="ChEBI" id="CHEBI:91175"/>
            <dbReference type="EC" id="1.14.99.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="10">Binds 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; eIF5A hypusination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the deoxyhypusine hydroxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.29" evidence="10"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668192.1">
        <property type="nucleotide sequence ID" value="XM_066812850.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045910"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03101">
        <property type="entry name" value="Deoxyhypusine_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027517">
        <property type="entry name" value="Deoxyhypusine_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697:SF5">
        <property type="entry name" value="DEOXYHYPUSINE HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697">
        <property type="entry name" value="PBS LYASE HEAT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0386">Hypusine biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="11">
        <location>
            <begin position="264"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8080717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="348" mass="37951" checksum="0DD811FB3D97874E" modified="2025-10-08" version="1">MSEAPKVATGADRDDSLPSTKVTAETIAALRESLCSESTPLPLRFRALFSLKHVAKHDHDEKNYLAALEAIGAAFVSPSALLKHELAYCLGQSGKTEATPPLRKALSDLQEDPMCRHEAAEALGALGFPENLDILREFLNREGENVAVKETCEIAIDRIEWENSEQRKQEKLRQRSDFASIDPAPSMPDSVQSVEELEKSLMDTKAPLFIRYRAMFALRDLASPPDLPTATPAVLALAKGFSDPSALFRHEIAFVFGQLSHPASIPALTAALSDTEEASMVRHEAAEALGSLGEEDGVEDILKGFLHDKEKVVRDSVIVALDMVDYEQSNQTEYALIPDSAPKTTVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBC6</accession>
    <name>A0ABR1WBC6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668267.1">
        <property type="nucleotide sequence ID" value="XM_066812925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045985"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="82" mass="9516" checksum="3081EDC6C4C8545C" modified="2025-10-08" version="1">MAPVAHAPGPPGLLKRLTRRFTGTFFKRTLDGKEKDFHMESIEAYQVEWKDVNDLLHRFFPKQANFSYKLVSMVRPGTCKTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBM0</accession>
    <name>A0ABR1WBM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008646</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668303.1">
        <property type="nucleotide sequence ID" value="XM_066812961.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046021"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF131">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="618"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="623"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="823" mass="89859" checksum="7A3E6A3C9E26BBFD" modified="2025-10-08" version="1">MDGSEFKKPDKRRRRPALACVACRRSKVRCDRNMPCGACVRSKHKTCVYEPGPTKANSRNSAVAAAAAAAGPTGPGPLLGADVGVESRFPISPAASSQAPSIVDTSTASFDDHVASSSHSIEAAAADEVSTSNCAVSQVAAAHDVDSLLQRVKELERQLEAARISPQANAQFNAPKIPDAAEASVTTYPTYLTDDIHTMNKSVMSKTRYFGQSHWMNIVTFLKPVMDIFDNQAMEVKSEIVMLLHQNKLLARTIKAQRMPELTFKFGLKIPPQEIADQLVDGYLRTFETVYRVLHVPSFKAEYEKYWTSPDSVSQAFVIQMQLVMAAGAGVYDDAHSMRKAAIAWVYEAQCWLMTPPLKSKLTITGLQNMLLLHFAREVAGVSGDLTWISISSVIRSAIAMGLHRDPKRLPNMSRADAEIRRRLWNTTLELALQSSMNAGGPPMISLDEFDTGPPSDCDDAELDTSGVDRNHQLTSAPANTNRFTDTTVTLVLRKSFPLRLAIVRHLNDINSMGKYDDTLKLSAQLQTAYKAASLSLRRFDSGGGRQPSAFQKQLVNFIFHHYFQSHHLPYLRWALWEPAYAFSRKMVIEMSLKLFSAVSESSSYGYSVGNTSIVSHRPSPHGAGVPGTATGTPSSITAHHHHHDDLNRLATNSCGFFRNATTKASMLIPVELQYQALENDGLGLLTPRPDLLAAVRDTSVWAMRRIRAGETNTKGYIMCRAMVTYVEGLAAGAEAAAAAGREVFGVLREMAGFVAEEGGQGGGGAQEVGRNLPGEFNVEGMEIDWDLDMSNALFDFTSIDAGFPSPGDPDFGLFNYGFNATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBY9</accession>
    <name>A0ABR1WBY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668500.1">
        <property type="nucleotide sequence ID" value="XM_066813158.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046218"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8081025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="37754" checksum="2F539782B5F5ED14" modified="2025-10-08" version="1">MTDFHSHFTQARDSVAARIKFRCALSTGPVMVALEAALMRNDYSIFSNALKSITRSKSCRQSGIRGGPWYTLQGGCKDFQICQACYCGIIAPCEMGPFFDLADSETNSDSMVRVCDLNPTAPRFLSYVEKLAQVVDVGDFSVFDRYVRQVSELAPCPRRSKSNESLWCCVDGCTVCPDCFETVASGTQFAHHFEVQRVTEPPPILCNLSSSRMRLKWAEACRDECIEDFLSMARHRQDMYKQATSAIEHIQQLHRSRFGQALADVMLGSRISAESRHSLTVGNRSAIDVSKSNSSLTVDTESGTLERLVRETLADARRRDEQRLIEEIENKWKAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDV7</accession>
    <name>A0ABR1WDV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667834.1">
        <property type="nucleotide sequence ID" value="XM_066812492.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045552"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="180" mass="19815" checksum="F173CBE0B6DD6292" modified="2025-10-08" version="1">MAATPCLPESITVMMEVEMGILAELSDAGFAWSPRLIGGDASFDNPALSLPYMVLSWAPGNPLKWTDALPRTEEHRRKILRQLVDIQLDLVSRTMKPTESNASSSSSALEFLTGIIDGKIGRVAEGKIPQLDPRSCFVHRALVQHVDSEIDISLPPMTAITHWNLTSRDIMVDDEFNITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEM3</accession>
    <name>A0ABR1WEM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668074.1">
        <property type="nucleotide sequence ID" value="XM_066812732.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045792"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="572" mass="61404" checksum="7996F4FFD1F444B2" modified="2025-10-08" version="1">MSSGQAPTQSGSSLMHPSHQTQHGDVMRLRQATGPPAPVTPAKRSDAEMDDVQFISSKPVKRQKVDHPTNSPIVNTTHVQTIQLQPPPNSQPVPQSQPVPYLVCGSSLVTPISAAPIADNDMSWPNSEIKSSHDRRITTGMVGLPSGFSDWESIFGYRGCSLPELESYSMSAAARLQSPKLSSPAISPKQIPNTITSKDSQLEPAPSEKNDMLQGNPTLRPGPNSSMTAVMNTPASQEIAKPSATDPTTVQQKETVPVAFEGCAEKVVDSTQPIAQQTPHDSSLEQIQHQQMPSEQPTTTPDNTTQAHAGKQPCKACMQMQQRAAFARAQGLPFANPNMPLHMLPPGPYHQSFGPQANPQFMSALQAGMHSFGPGFGPMMVPMNTQNYSGAAMAPPALAHQHAVQPMPPRPTAAAYQQPPTGKTSETSRENAAAAATTPTPPISHAAKLPQALAEPHRRRGRDVPGKVPLEEVAKRHDTTVEKVADVFAAIIQVPLLRCPKDRRRAGRLAHERVKEYNKTKRELQEAAEAAKGQMGNRNNNSTYGGDGQQGAIQPQIVVRPLDVANALGPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLR2</accession>
    <name>A0ABR1WLR2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668943.1">
        <property type="nucleotide sequence ID" value="XM_066810020.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043080"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="145" mass="15998" checksum="3DD65331F08B0CF9" modified="2025-10-08" version="1">MYSQPSGDPRLSAASTILPGRPTRSELSQEQVIASREPAARIIEQRRAEQAALEAQQRQAAAAQQQSRGPQQSTANPQQQYQAPVRPHQAAAARAQQAPAPALKPETKEEKEERIEAARKRFEEGRGFDDDDEFYPGHRRSGGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMS1</accession>
    <name>A0ABR1WMS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006111</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669349.1">
        <property type="nucleotide sequence ID" value="XM_066810426.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043486"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05676">
        <property type="entry name" value="M20_dipept_like_CNDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017153">
        <property type="entry name" value="CNDP/DUG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051458">
        <property type="entry name" value="Cyt/Met_Dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270">
        <property type="entry name" value="BETA-ALA-HIS DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270:SF4">
        <property type="entry name" value="CARNOSINE DIPEPTIDASE 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037242">
        <property type="entry name" value="CNDP_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="6">
        <location>
            <begin position="207"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="467" mass="51634" checksum="B08310AD911EA1B8" modified="2025-10-08" version="1">MAPQLDGYFSKVDELSSHFIDRLSKAAARRPDVVRMGQWLETELKALGAEVEMRPLGKQPDHPELDLPPVVLARYGRDKSKRTILVYGHYDVQPAEKTDGWATEPFTLTVGEDGRMFGRGSTDDKGPVLGWLNAIEAHQEAGVDFPVNLLMCFEGMEEYGSEGLEELIEKEGKGYFADADAVCISDNYWLGTEKPCLTYGLRGCNYYSVEISGPGADLHSGVFGGTAQEPMTDLVRVLGSLVDTHGKIQIPGIMEQVAPVTAEEENLYDNISFTMDNLHESLGSKTTIFEDKKPTLMARWRYPSLSVHGVEGAFSAPGAKTVIPAKVIGKFSIRTVPDMDIDQTNECVYKYVRETFAKLGSKNTLNVYAQHTGKWWVASPNHWNFRAAGKAVERVWGVQPDFTREGGSIPVTLTFEQATGKNVLLLPMGSSTDGAHSINEKLDKKNYIEGIKLLGAYLHYVAEEKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNN4</accession>
    <name>A0ABR1WNN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pathogenicity protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669586.1">
        <property type="nucleotide sequence ID" value="XM_066810663.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043723"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="147" mass="15520" checksum="20DAF70884B1494E" modified="2025-10-08" version="1">MSFIASQRERLNFVLNALDREAKALQRGEQEGHDGDRKPGSMSLDGSDNNGHNNGSGIERPPSGHSVWSALSKSRSEVDFEKIEAESASEEDENGLRRRAEASTPGSNGGRAGWSFLGWGTIGGSAGPATPVNESPARGLSSGVDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNN5</accession>
    <name>A0ABR1WNN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Covalently-linked cell wall protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_006398</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PIR protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669636.1">
        <property type="nucleotide sequence ID" value="XM_066810713.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043773"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054508">
        <property type="entry name" value="PIR1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051153">
        <property type="entry name" value="Yeast_CWMannoprotein_PIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000420">
        <property type="entry name" value="Yeast_PIR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47254">
        <property type="entry name" value="CELL WALL MANNOPROTEIN CIS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47254:SF1">
        <property type="entry name" value="CELL WALL MANNOPROTEIN CIS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00399">
        <property type="entry name" value="PIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22799">
        <property type="entry name" value="PIR1-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50256">
        <property type="entry name" value="PIR_REPEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047249888" evidence="8">
        <location>
            <begin position="18"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall mannoprotein PIR1-like C-terminal" evidence="9">
        <location>
            <begin position="79"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="225"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="259"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8085127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="364" mass="36933" checksum="8DAB29260E2DE086" modified="2025-10-08" version="1">MKSTIVASSTLLGLALAVPQGITDKLTPTGSAPAGCTGSFDGSFEITVAKITEKKRSVMPERRAECGKGGVLVMTLKDGTAKDSQDRIGYIASNNQFQFDKPAQAGALLTSGFSVCENNVLALGDTKTFYRCLSGTFYNLYNKNWAEQCEPVSIIALPCGGKDTVSQVPDGQVVGTTVVQTTIVTALSDGQPQVVTTGVPIPLCQIGDGQVQVHTTPCASVTSVPATKATPTAPVSQISDGQIQVPPPNTSAPPPPAAPTGSAPAGPQPPATTAYPTAPGAPSAPSAPSAPSAPSTPTGGNSTVPTSPSSPSSPNVPSQPSPSSPAGTPSAPLLAGQARWPLDRLVLSSSAWWLPLSLFKFSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNX3</accession>
    <name>A0ABR1WNX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006013</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669251.1">
        <property type="nucleotide sequence ID" value="XM_066810328.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043388"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668:SF53">
        <property type="entry name" value="TMEM14 PROTEIN HOMOLOG YJR085C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14, 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="11315" checksum="01195D19419B8DA2" modified="2025-10-08" version="1">MAEHPSFTLAGLLAVGGTMGYVRTRSTPSLVAGIGLGVSYAYAGYLIKQNRDYGTELALGNSALLTASAIPRIIKTGGRGPVPLALGSAGLLASYYYVRKVQEFRYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNZ7</accession>
    <name>A0ABR1WNZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006419</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669657.1">
        <property type="nucleotide sequence ID" value="XM_066810734.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043794"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="185" mass="20306" checksum="49C86F07BC88E880" modified="2025-10-08" version="1">MPDENNDFDAAMVNNIHQCLPEVYCPRIPVGKNYGNDQRLFDLHVQLRHIDLHEIYVAYKNHTTLPKYGVDLSNGLFAELMIRWNTGGIHPIGIASHVFGNPAITGMKASIQTSLGSATLAMEPDVRDSKIMRGLTLDLGPVKSQAFSGIGTIAGIFRVLNTPRSLLSQDHAVASMEQTKVHTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPJ1</accession>
    <name>A0ABR1WPJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">3-oxoacyl- reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_006599</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669837.1">
        <property type="nucleotide sequence ID" value="XM_066810914.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043974"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF111">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_1G10100)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="9"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8085328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="308" mass="32519" checksum="E95515AE2133BF55" modified="2025-10-08" version="1">MSPRPYDGKLGIVTGGSRGIGAAVAKRLAAKGCNLLLVFTSDSSKDLVQALCAELYDQHRVSCAQVQADLSQAGAACEKIVAAARGFHASLRRDGELQVDILINNAGVSSNQFLNDADKGPIAEAEFARVYNVNVLAPLLLTQALAPYFPRPTSPESGSFVKTKGRVVNVSSVSSSIGYEGQSVYAGTKAALEAMTRCWSRELAGRATAGEKFWRINQAYCDAAPLQAYTGGSAETAAEVKELMGDGTQDKDAELQRFDSLVREKMGGRRPGFTSEIAGTIDMLCSEEAGWTTGSVVCANGGMKMSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPR2</accession>
    <name>A0ABR1WPR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006795</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670033.1">
        <property type="nucleotide sequence ID" value="XM_066811110.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044170"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021102">
        <property type="entry name" value="PNGase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056948">
        <property type="entry name" value="PNGaseA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31104">
        <property type="entry name" value="PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25156">
        <property type="entry name" value="PNGase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12222">
        <property type="entry name" value="PNGaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047089479" description="Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-terminal" evidence="3">
        <location>
            <begin position="105"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="671" mass="72823" checksum="70E71F2175DEB4FC" modified="2025-10-08" version="1">MYLIQVLLLAVVAALAPTTAADARHSRQHVLSRRSVKAKPPYFGHRDLMMTMDSEPADDDKTPTANAPRAVTTPLECFQVAEPILTDQGLTLRGQSQPYADARPEAACSQTLMVHTFANSYGAPFVGNYTPPDCDFDHVVINFTTLVRGRQFDRTGVMYLGDNEVWRTSTAEPNPSGIRWVWLKDMTPFLSLWKQPQTIIFDLENIVNEQYTGLLNTTLTATFFKRPSPSPSPSANTTAAAGSYSPPADQIIPITQRLGAQGKPSQFTVPEQNASNTIADFPRHARRAVFAVDVKGQGNEEFWWSNVPQSAARTFDRTYGTYPGYSPWREVQVAIDGQLAGVVWPFPVIYTGGVVPQLHRPVVGIDTFDLREHEIDITPFLPRLCDGKSHTFNISVVGLVDNGSDQAALSTTTESSWYVTGKVFVWLDEDAQSVTTGEIEQVSRSEPTIEFAQKITQNATGFNQTLDFALTVSRKFSISASVKTQTGESTATWSQTLDYSNVGQVFDYGNGEVNMFSITGLDQAKSGDGVVEYATNYSYPLFCNQTQVTSPEGNLTLTAKLNQGLGLEVSGDAVFPTGLEAFSSASEFRGSRLQTSQNGTAIYHRAADNSFSTGHGQTSQTFAFSGIAGEAGSGAAGTLLYSRRVGAANDSVSADNEEVVGTGAASLERVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ30</accession>
    <name>A0ABR1WQ30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670154.1">
        <property type="nucleotide sequence ID" value="XM_066811231.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044291"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF177">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="204" mass="20635" checksum="B6168E693FBFC09E" modified="2025-10-08" version="1">MIPSILATALATAIGSGLAGKCQVFQPFLIASGIVSTIGCGLILTFDLNQSLGSIIGYQILYGVGTGLGVQLPNLVATVTSAAEDVSTAVSTVSFFMLLAGGWGVAVTDAMLNNLLLQKVPHYVPGLDGHAVLAVGAAGIEDAFTGQVLEGVRLAYLDGLHAGWALGTAAFGITFLWALLPRWPGRLTAPTGAPGAKGMAADVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRM7</accession>
    <name>A0ABR1WRM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669382.1">
        <property type="nucleotide sequence ID" value="XM_066810459.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043519"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="157" mass="17688" checksum="E3330343E69F5C75" modified="2025-10-08" version="1">MVAVYAKRVWLIWPFEEGTPVAVPFCRVLRELQIPYRETSSGVSEETSRSDGLALGVLRQGFVDDMDRKALAGTGYLGSPYRQSALSGGFLYLILTNLDQVRCKELEIMDRSINIPHQLLLGLIKFGSGVHPSLLRDNLAECQKVENRHEKRRTGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS98</accession>
    <name>A0ABR1WS98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006969</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670207.1">
        <property type="nucleotide sequence ID" value="XM_066811284.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044344"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="14"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="350" mass="37065" checksum="8A5D2FBE81C06497" modified="2025-10-08" version="1">MSNLQKAIVVTEIGQPAVLITNQPIPHPGPNQVQLKVAVAGLNPHDQKMRDVGMFVTDGSLPQVLANDVVGVVTQLGANVSDYKVGDRVVSHARMGSWTEPQSSEPGLQEYALANVGAMARIPPGVSDDEAATLPINVMPSVVALYRVLGIPAPWTEAAAGFDYAGTTLLIIGGGSNNGRFGVQIAKLAGVGRIVVVGGDQAELRSYGATHVLDRHGGSEAVLARIRAVVGDDLVYAYDTVNDPAGQTLGLNALSSRKKGVMARLVPTGPVDEARVVGKEAGFELRDAIGMSVYQKDEALAFWERLPGYLESGQIKPLKYVVKEFSAASVNEVLNAYRDGKPVTKTHIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX02</accession>
    <name>A0ABR1WX02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002659</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670592.1">
        <property type="nucleotide sequence ID" value="XM_066806974.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040034"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF353">
        <property type="entry name" value="METHIONINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="7">
        <location>
            <begin position="721"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="567"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="625"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="899"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="651"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="914"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8087698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="924" mass="99712" checksum="BAAB653AFC3FDA3F" modified="2025-10-08" version="1">MPFWSKRAASEPGAEAAAVDGNASHSDISVVKDGGLTYTRAQGHHSRIAGTILNNTGSIGLALIYWVIGAIMAFAGLGVYLELASYFPNRSGGEVVYLEQAYTRPRHFFPVAFAVQSVVLSFASSNAIVLSNYVWRIAARASPPTQWETKGVAVAAYTLAVVCVIAHNKYSLWAVNVFGAVKVITLVFISITGLVVLGGHVSTQRVPDPHANFRHGFEGTTDNGNDLANALVNIIFAYTGYSNAFNVVAEIKNPIKTLKRNCTISVIIVAVLYFMCNIAYFAAVPKQEFRKSKEIAAGVFFTAVFGKGHAETVLNVLVLLSAFGNLLAVLIGSSRTIREIGRQGVLPFPKFWVTTKPFGTPIGPYLLKWIVTFIMIVAPPAGDAFQFVVSLKSYPESMFFLAMAAGLYIIRRNQRRIVGEGHRPEFKAWDVAVVFFILIQVYVLVMPWFPPKGGIYAGNVSFFYATYCLVGIGVVVGCFIYYKAWISWIPRWKGYAIRPEIVDVGDNGAKTHHLVRVPNAELAEWDDAHDEAGNLRRRGVRSGVTVSDKGSDGEVVREPNPLHLYLCDRPDSNGEGCETEAGSGRSRKGLGGCRKGCTEKAEKAAAKAATKTAAQAAEQAAAEAAAEAAEQASEKAAQKTHTVAQPNSSTSPPPPPPPPKKPSPSVKPSAPRAGPRTSLPDIFVRLSRSPLQRYAFFTPSSPLICSLVQPGGIRSNFGSGVAQCERILGYTFKSKALLAEALKVDQTAIPEAQFRLKGALYYLPYNKRLAVYGDSLLRTYLARQWLELGPVEGTGGLWGAKTNLALSDQYLGGIYRKLRLDCCISVSSDGAYNSAGGVNLPSERNPKYMATTVEAIAAAAFLDGGNPALEAAMKSFGMNKLFAKSPVIYDFFRHGQPESIATTPPPPSVPSVDFGHDVKTPSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX28</accession>
    <name>A0ABR1WX28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670613.1">
        <property type="nucleotide sequence ID" value="XM_066806995.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040055"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046148749" description="Tyrosinase copper-binding domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8087719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="341" mass="37483" checksum="FB1D932F6D1B3EA2" modified="2025-10-08" version="1">MHHLSLFTLAASCLSVLAAAVPVMPGEPIPSEPAAPKVCRNPPKRLEWRQMSKSQQMSYIDAVMCLTMTESKSGIARAINRFDDHQAVHSVQTPNIHWVGHFMLWHRYLVATYEKALREECGYEGGQPYWDWSLDARPHDPDSLAAFPEAIFGPGAYSFGGNGDLVTPTPEQNPLNLTGGTGGGCVRDGAFTPDRFRRDFVPWILNSFADPARVEEVLEQPDYASFARSVEKVPTFDQPNIHGSGHFGVGGVLGTIGNAENSPGGRPLFYLHHGNLDRVLWMWQQKDPETRLNQVGGPVVPFDYGGQNVTLDFTVNLGALAGDATLKQLLDTQSGVLCYTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX31</accession>
    <name>A0ABR1WX31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Structural maintenance-chromosome 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002677</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670610.1">
        <property type="nucleotide sequence ID" value="XM_066806992.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040052"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF172">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="9">
        <location>
            <begin position="816"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1270"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="530"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="695"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="969"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1349"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1272"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1294"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1326"/>
            <end position="1344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8087716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1583" mass="175867" checksum="3817041DD65CC5A2" modified="2025-10-08" version="1">MSGRPSRRAAAARRAVIEESSEDDGVGDTTGIKKQEDDSEDEFSIAPPPPPPTRAPRKSTAAKRKTAASAGASSTTTRARRTRRSAAPSSAEPSEILDADTTSTTVRSAQTDEIAEEPEVEEPVKKLPVPRKRKTAAKTAAPRKVSRKSETPEVQQPPPDVEQTPARSTSEAPQETPAPSTSEPPQETPSAAQIPDPQSPQPTPQSTMPPTSAQPPATPLPDNKQLKNETPATVKHIKTGDETPATVKPIKALDTILERPMDIVLKSRAQMTVPIPEETGPKSRTVISYLILNNFKSYAGRQEVGPFHASFSSVVGPNGSGKSNVIDSLLFVFGFRASKMRQGKVSALIHNSAQHPNLDHCEVAVYFQEVMDLPGGGSEVVPNSQLVISRKAFKNNSSKYYIDGKESTFTIVTTLLRDRGVDLDHKRFLILQGEVESIAQMKPKAGNEHEDGLLEYLEDIIGTSKYKTPIEESATEVETLNEICMEKSGRVQHVEKEKNSLEDKKDKALAFIRDENELTLKQSALYQLYISECNDNVNVTEEAINQMQAQLDDELEKHQGSEHHIKQLQKTYSKDSKEYEAMEKEHQALAKEVAKFEQERVKFDEKRKFLTDKRKKLEKTIANAEKSTTEADETIEQCTEEITTSTEQIGALEETIQEEEAELATIRDSLKGKTQVFSDQIATKQKSLEPWKDKINQKQSAIAVAQSELTILEEKANAGAVALEEMNAKITSIAEGREAKIAQLEECENEKAQLEKEAKKVESDLAQFASKEHIIRNKVSNARQKADEARSSLASNQNRGNVLTALMRMKESGRIDGFHGRLGNLGAIDPKYDVAISTACGALDNFVTDTVEAGQQCIEYLRKTNLGRGNFMCLDKLRARGMDAIQTPENAPRLFDLVSAKDDRFRPAFYHALQDTLVANDLAQANRIAYGAKRWRVVTLAGELIDKSGTMSGGGNTVKKGLMSSKLVADTSKEQVTQLEEDRDVLEQKFQKFQDQQRELESRLRFINNQIPQLETKMQKLNLEIQSAEKNIVDAKRRIKELGKEHQPSQTDDNRAAALQKEIAKLEKEVTKLHSETEDVEAEIKELQDKIMEVGGEKLRAQRAKVDSMKEEMASHNEAISAAEVKRAKAEKSKTKLERDHAKATKEVDAAIRDLEKLEAEVENQGEKSELLQGRVDEAEAALTEKKEELATIKAELDEKTTELNETRAVEIEMRNKLEENHKALGENQKRLRYWNEKLSKLHIQNISDLEGAPAPKKADAADTSQIAEGAETAEGEPTEPMEGEEPAKKGNNEDEAENGEDDEDAEGEDEDDSGEDEAETSKVNAGDKTRGPDELPRFTDDELKDMSKERLKAEIAALEEKVQNVNVDLAVLAEYRRRVEEHASRSSDLATAVAQRDAAKKRCDDLRRLRLEGFMEGFSTISLRLKEMYQMITMGGNAELELVDSLDPFSEGILFSVMPPKKSWKNISNLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFRNVSIVANYIKERTKNAQFIVISLRNNMFELAARLVGVYKVNHMTKSVTIENKDYINRPVPASQRPAGGGMTMTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXC8</accession>
    <name>A0ABR1WXC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 94 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002777</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670710.1">
        <property type="nucleotide sequence ID" value="XM_066807092.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040152"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11748">
        <property type="entry name" value="GH94N_NdvB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="entry name" value="Glycoside hydrolase, family 65, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="GH65_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033432">
        <property type="entry name" value="GH94_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052047">
        <property type="entry name" value="GH94_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037814">
        <property type="entry name" value="GH94N_CBAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005194">
        <property type="entry name" value="Glyco_hydro_65_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010383">
        <property type="entry name" value="Glyco_hydrolase_94_b-supersand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37469:SF2">
        <property type="entry name" value="CELLOBIONIC ACID PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37469">
        <property type="entry name" value="CELLOBIONIC ACID PHOSPHORYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06165">
        <property type="entry name" value="GH94_b-supersand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03633">
        <property type="entry name" value="Glyco_hydro_65C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17167">
        <property type="entry name" value="Glyco_hydro_94"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl hydrolase 94 supersandwich" evidence="4">
        <location>
            <begin position="77"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase 94 catalytic" evidence="5">
        <location>
            <begin position="317"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 65 C-terminal" evidence="3">
        <location>
            <begin position="746"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8087816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="817" mass="91882" checksum="5D327409B39EBA0F" modified="2025-10-08" version="1">MAPPLLGPTEDGSRYELYSPTALPKAGGFLWNQRMMVQMTCRGYAVAQFMQPEPAKYAHAPNLEARTFMQPEQAYYAHHPGRFVYVKDEESGDLFSAPYEPVRAPLDDFVFSVGKADLAWKAECRGLRVEMALVIPTHDVAELWRVRVVNTSGRPRRVSVYPYFTIGYMSWMNQGAVYREDLGGIVGTSITPYQKAPDYFKNKLLKDKTYLLCETPPDAWEAMQEAFEGEGGLHNPSAIQEPLLQKSDALYETPAAAVQYQGVELAPDEQKEYRFLFGPALDDAEIRAMKAKYLSAAGFAQTAADYAAYIEAGSGCLRVVTPDAQLDNLVNHWLPRQGYYHGDVNRLTTDPQTRNYLQDNMGMSYIRPGVARQAFVTALSQQEKSGAMPDGIILVEGAELKYINQVPHTDHCVWLPVALEIYLAETGDWALLDEPIRDGHGDTYTAFERFSRAMDWLLSDAARDERGLHYIAQGDWCDPMNMAGWKGKGVSGWLTVATGYALNLWADVCAQHRPAVPALAQRYRDGAWDVNRAANAHFWDGAWFARGITDDGVTFGVRDDPEGRLWLNPQAWALLGGAAETREQRRAMMEQVEAQLGTPYGLVMFAPPYTAMREDVGRVTQKYPGQGENGSVYNHAAVFYIYSLYALGERFDTTADSNSSDTASTKEEKQEIADRAYRYLRQMIPGPDEADYRQRGQLPVYIPNYYRGGWRTQPRTAGRSSQLFNTGTVSWVYRCFIEGLCGLRGEPDGLRIRPQLPSHWDHVTVERRFRGAVFHVEIRRSPDAREVTVEYEGKVLPEARFTGIEAGKTYQLSVTVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXE2</accession>
    <name>A0ABR1WXE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670728.1">
        <property type="nucleotide sequence ID" value="XM_066807110.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040170"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF56">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="471" mass="52318" checksum="AC953330741C4555" modified="2025-10-08" version="1">MPTSQSHSSTQSNMGDSGEYATSFEERRPKILEICQDLWPGAAISITSPSGGDRSVEEYFIAVSYSSYLDGMNQHLNHDRYVLQIPRRPDEVADRAAVLGHIDVFGGEGVQLLTPEAFHVNRTPDNPLGRPYLILTEHPGCNLGKVYQNMSQEQKIKVATELGRAFCELQVDPAPFCGYPSTDPNEDDGEGRCIKPFQIKKNDNEADSTDWDAMMNFLPADVDHTEEDPAAALTRASFLKDGTPHLKARQIVRLSFLRWIHHNRHSSSSSSTAPWKRDANERLLQRSLAVLEEIMRRNPDVFDSDHICLHNPALGAAENILVEFAGDEGRERESGAPQIMGIVDWASTAFEPRFAGCRPPDWLWSFPRRRRRRNDPVRGPPGPRRVLEQLPRSNAGGGHRVVPPAGPVGTAGPARPTDARRRRRGEARLRRGGRAGVLPGRVRRRGSVCAAVLRGREGVVALVRCRPTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY18</accession>
    <name>A0ABR1WY18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box/LRR-repeat protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670952.1">
        <property type="nucleotide sequence ID" value="XM_066807334.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040394"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="159"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="677" mass="74633" checksum="2D786EB66B9D2A38" modified="2025-10-08" version="1">MAGISADTQPPPTSLVEELVNEESPGVTQPEGPIKGKRRQRLLQEIQRISSSSSLRQSKRSRSSQSPYATRGSLSCVSLSGNSPFAQYPTGAASPGYLAHTSPGTPTTEFPNFGEYETRLAVRKLAHGSSPCLAPSSIALPADLITNRSRSGTTRKPPYDFWANMPDEIRVQILSYLEPKELVRVSVLNREFHRFCFDGQLWTNFDASDFYKDIPAESLVKIITAAGPFIKDLNLRGCVQVEHERKTEVVVRACQNLINATLEGCRNLPGATLHSLIKANQRLANLNLTGLPAVSNSTCKIVSQHCPQLETFNVSWCKSMDAKGIRMVVLGCPKLRDLRAGEIRGFDNLEVAKAIFETNGLERLVLSGCTELNDEALRTMLHGVRPSVDILTDRPIVPARKLRHLDLSRCKSLTNHGVKALAHLLPDLEGLRLSGCNAITDSALEPIVASTPRLTHLELEDLTELTNGFLSKHLAKAPFASKLEHLSVGYCENISDTGMIPVMKNCTSLKNIEMDNTRIGDLVLAEASAMVRSRAARSSTYESRPYVGLRLVVYDCSMVSWTGIREVLSWNAEIRQPSGTTATYPTEIIGLKCLYSWQQTVDQHTQRVLRGDFLAAGRLERKWTDYMQAIEEAGAGGAGIRRRRRRAREAQQLHADEEGAGAGRRRARTMATSCAIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYE7</accession>
    <name>A0ABR1WYE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">M-phase inducer phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003140</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the MPI phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671073.1">
        <property type="nucleotide sequence ID" value="XM_066807455.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040515"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01530">
        <property type="entry name" value="Cdc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000751">
        <property type="entry name" value="MPI_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF17">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00716">
        <property type="entry name" value="MPIPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4 6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="8">
        <location>
            <begin position="365"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="509"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="545" mass="61277" checksum="56D40FAACDF5F19B" modified="2025-10-08" version="1">MDASSPLAAMHPAPPPTWGQSHDIYRSHSHYSNSNPFGSGTLNIRDHLQRSKPDYFSLKSVRGSSPTASLAADLSQNFRIDTEGSPRFPTPRRALFTSNMMGGIENRDYITTPPLPASSSPVPMSVGDMMEMDISPLPHKTLYSNTSIEITSPTPGELPDDDDDDDCMMMESPIALSRPPSMTTLEPPKPLITDSRKRLALRRPSLSRAKGHSASGITGRLHPENHLNAFKFGSEHRVPSGLSLGECFQDSPLNYVGLKPPTAPTLTSHAPHSRRPSNPFQRRPRQYRRSLSMFENPMDVHKPKNEDPVPASTLQSVMDIEDVQDPALPHFFPEGESDSIPRISRETFLDVMDGKYSHEYTQRMVIDCRFEYEYEGGHIDGAINYNDKELLARHLFEQPMEGKVLLIFHCEYSAHRAPLMARHIRSEDRTVNAEHYPHLTYPEVYLLDGGYSEFFIEHPSRCYPQSYVEMNDSEHVMTCEREMGKLQQKRKGLSRARTFAFGARESMVDESPTAPGRCHDSPSSMIGNSPILGADRTTSRRMASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYN1</accession>
    <name>A0ABR1WYN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671162.1">
        <property type="nucleotide sequence ID" value="XM_066807544.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040604"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045633610" evidence="1">
        <location>
            <begin position="21"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="135" mass="13913" checksum="128F7EC2F33A659C" modified="2025-10-08" version="1">MYRFIIALAMAATSFPYTTAQIATQFQAPSVAFSNNAGCSNPGTSSSMIAGECTAIPTTILGTASQSMNVTYPIDNVDLNCPLTFYNDAMCAVGGDAMPYTGANVCVEVSNYGSVKAKCSNILTGATYTAPANSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYR1</accession>
    <name>A0ABR1WYR1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003224</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671157.1">
        <property type="nucleotide sequence ID" value="XM_066807539.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040599"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="JDOMAIN"/>
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        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045044635" evidence="8">
        <location>
            <begin position="23"/>
            <end position="431"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="9">
        <location>
            <begin position="44"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="212"/>
            <end position="289"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="362"/>
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        </location>
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        <location>
            <begin position="212"/>
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        </location>
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            <begin position="241"/>
            <end position="257"/>
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            <begin position="269"/>
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        <location>
            <begin position="362"/>
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        </location>
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            <begin position="377"/>
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        <location>
            <begin position="411"/>
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            <begin position="422"/>
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        </location>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="47406" checksum="46A0683F80768890" modified="2025-10-08" version="1">MKFSTFSLGFLALLTPFTAAWSKEDQEIFRIRDEVAVHEGPDVSFYDVLGVAASASHDEISRAYRKRTQALHPDKVRRQLMADKTAKSKDKKKSAVKSPSQSEIKAAIKAAGDKQARLGVIAGILKGASRARYDHFMSNGFPTWKGTGYYYNRYRPGLGTVLVGCFLAGGGLFHYVALYMSWKRQREFVDRYIKYARNAAWGENVGIPGIDTAATGAGTATPPAVEEEQPPMMAMNRKQRRMQERDSKRENTKENRRQGRGRAGKPASGSATPVPQTQAGNGSGPTGAKKRVVAENGKVLVVDSLGDVYLEQQDEDGNMHEFLLDPNELPQPSIRDTAVFKLPIWAYTATVGRAFGAKQDSYEEQDLAEEVAEQLAEDSSSSDAPQRTPSSDSAEDYEMVDTSKSVEDLAQKATGSQSQSSKAKKRNSKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYR5</accession>
    <name>A0ABR1WYR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003237</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="1"/>
            <end position="22"/>
        </location>
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            <begin position="18"/>
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    </feature>
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        </location>
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            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
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        <location>
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            <end position="185"/>
        </location>
    </feature>
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        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="358" mass="41108" checksum="A21324A6F22E14D5" modified="2025-10-08" version="1">MLPRRTNKDCRKRWYKVRSDFIKGTWSHEEDRKLQQAVQQHGLKWALVSRDVESRNADRKVCKRWQHGLRPDLKHTPWQPEEDAKLLQAMEKHGNKWKKIATLDLPNRSSHDIRNRSVVLSRREKRLSKKGHSTAAHCQDQAASQPDLRCRTLDDMLQSQGGDEVNDEDTAPESEEDDGCDDYDDSGVSVISYHSQLQSPSSDIHMDSGFTSGAASPRPRRSHSIQEGSNMVAVDDHDWTRFTMLQEQLLKAEQLQQLHQLQQVQATPPPTPVTPTWYEMPGLSDATVTTPKNCYPSYLPMSVMPFPTLAQDNMTDESYLGIFDNYVHSNDIGPMDFRPQVSHDWRYEMGYTADPFMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYX4</accession>
    <name>A0ABR1WYX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671201.1">
        <property type="nucleotide sequence ID" value="XM_066807583.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040643"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364849" evidence="1">
        <location>
            <begin position="23"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="140" mass="15026" checksum="7EE500B3C9EFF96F" modified="2025-10-08" version="1">MQFTVFLTSIAAFAAGTAHAAAVPRQGKDNPRLAQFRIFSDVGCSNLNQGFYTVDRDQTSTCGQLNNVPVESLKLERLEPAADGCELRLYISNDCTEKAVKASVGVCNDATETGPSVGIPTWNSWQMVCPSSARNGTMSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ86</accession>
    <name>A0ABR1WZ86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003427</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671360.1">
        <property type="nucleotide sequence ID" value="XM_066807742.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040802"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF1">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ERV2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="80"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="239" mass="26072" checksum="7CB13EF9367B63F3" modified="2025-10-08" version="1">MARHISMVVMLAVAAFLGLTFMMSSRVRTDSVPQVFTPPLNGGKAAPAPAAAAVSDSKMEGIDLSSSVISGGVIAPKLENATIKAELGRASWKLLHTMMARFPDKPTEDDSLALKTYMQLFSRLYPCGDCARHFQGLLKKYPPQVSSRNAAAGWACFMHNQVNERLHKPLFDCNNIGDFYDCGCGDEDKDKDKNKDKKKEGAPTELKLEKDSLVNSLPLAVSAQWLPRTVTDISGRPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZI4</accession>
    <name>A0ABR1WZI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003501</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671434.1">
        <property type="nucleotide sequence ID" value="XM_066807816.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040876"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050072">
        <property type="entry name" value="Peptidase_M20A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808:SF30">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="4">
        <location>
            <begin position="230"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="390" mass="41917" checksum="B280C57A354BC360" modified="2025-10-08" version="1">MHVFIPDSILSSIAKPEHKSDSRAHSSLRQLAAEAIERRYRDALLSLHKELVEISSVSGDENAVGTFLVDYLTERNFQAQLEFIPPSFNSSSSTPSADADASKPRFNVLAWPGKTRSPKPKLLVSSHIDTVPPFIPYSSSDADPNSNTVISGRGSVDAKAAVAAQVIAVLELLEAEKVKGEDVMLLYVVGEEVGGDGMRYFSATLDELEPPPALRPPSSASRPRASWRAATRGFLGCDIVAHGHAGHSGYPWLGKSATEVLMRGLVKVLDTDLGSSERFGNTTVNIGHIEGGVAANVIPEKAQAKIALRVAIGPQDGEDGGGMIVKERLWKTLKSVDEEAFEMTCHKPYGAVDCDCEVPGFENITVNYGTDVPNLKEIIPGTSTDPARSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X034</accession>
    <name>A0ABR1X034_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial inner membrane protease ATP23</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003675</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Peripheral membrane protein</topology>
            <orientation evidence="1 9">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671608.1">
        <property type="nucleotide sequence ID" value="XM_066807990.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041050"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019165">
        <property type="entry name" value="Peptidase_M76_ATP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711:SF0">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09768">
        <property type="entry name" value="Peptidase_M76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="277" mass="31436" checksum="7895314344B18515" modified="2025-10-08" version="1">MAPPQSPGAGAVSEAALPSSSSAATASTSTATALPTNYLPPIVKNDPARTGFDPQTKWWVNYFKILAGQVTPEGQFHYREWRTTANEAADCKRCEDWRDFALQHSPTVRFLREKIEALNGRLDKDNVICRRCPARLTEDGEVHRQSGGFSPDHGILICANEVRDRTHLEDTMAHEMVHAWDHLRWKMDWTGDKDLKHAACTEIRASMLSGECRWARESITRGNWTLTQQFQDCVRTRAVISVMARPRCKDDVQAVKVVNQVWDSCFSDTRPFDEVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0A1</accession>
    <name>A0ABR1X0A1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium/calcium exchanger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003814</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671747.1">
        <property type="nucleotide sequence ID" value="XM_066808129.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041189"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051359">
        <property type="entry name" value="CaCA_antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266:SF0">
        <property type="entry name" value="MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266">
        <property type="entry name" value="NA+/CA2+ K+ INDEPENDENT EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="720"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="751"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="785"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="821"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="851"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="897"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="934"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="113"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="789"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="269"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="402"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8088853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="962" mass="104059" checksum="93B8E38A7902870C" modified="2025-10-08" version="1">MRRSRLGSGNGPRLARFARPTSRPFYATVLVLTLLAVYSLFVRGPVPSPPRQHPSSLVKRAGEDCRLVHHAADQCAFVLRNCIDDEAGLISYLSFYYCTLGRVQPVAFVILVAWLGLLFTTIGIAASDFFSVNLSTIATVLGLSESLAGVTFLAFGNGSPDVFSTFAAMSSNSGSMAVGELIGAAGFITTVVAGSMALVREFKVSKKTFIRDLCFFIVAVSFSVGFLRDGHLHLWECCTMIGYYIFYVIVVVSWHTVSKRKAARRSRSGSSQGLLLDGAGTGHSSRTLEPYSDDPANLDPAHKPAGVDGVVLEAGLRVDFDSPDEDEGSDDPQHIAAEMAAEMRVSRPRGRRTTTTITPIRPSLIGALEFRSALSNFEEGESARPSMYTRSHSTDWAVHCRTESRGELTPQRRRGRARIHRGAIPSSLDEDLTQAPPKPARKLDHARSPSVRTVGGKLAPPQTDSTGHLAVQEPAVETVSPRTRPQNLQLRIPAPSPSGSEQSSPATSPFPHYSESPMVLSPSGPNGPPLMLPSPAFEHNPFSPAFVKKTKQKRACWWPYEILPAPHVLMSTMFPTLQGWRSKSALDKFVSLISVPSIFLLVITLPVVESEVADGDSDQSDVEQPAVGLGNAPAPVSYEPVGAIESETEWQRYRRHTRSRSASRHPSPGPMVILATPDYGTVSGSRQAMEPRYEPLHKVDAGIGPDDSSLNSEEGGWSRWLLILQIFTGPLFAVCIIWLNTAEDLRNPFQVLVKSILGSLVFSLVLLGLLLATTSPDTRPKYNHLFCYMGFIIAVAWISTIAGEVVGVLKAVGVILDISEAILGLTVFAVGNSVGDLVADITVARLGYPVMALSACFGGPLLNILLGIGLGGAYQTIHTANHHHNKHPDRPVHYKAYNIDVTASLMISAVVLLITLLVLLVVVPMNKWIMSRKIGFGLIGLWTVGTVANLVIETTGVWGEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0J4</accession>
    <name>A0ABR1X0J4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003850</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671783.1">
        <property type="nucleotide sequence ID" value="XM_066808165.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041225"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF400">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="12"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8088889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="212" mass="24206" checksum="70A976E32F2C98F7" modified="2025-10-08" version="1">MRGLHNELTDRYKVLKILGKGSFGVVRLVKEKTSNGFTNQLLPYKKPVYAMKVIRKSAMLRTSQEGHLRAERDFLVSSEGSRWIVPLIASFQDPANLYLIMEYMPGGDFLGLLIRENILNEPVAKFFIAEMILCIEEAHSLRWIHRDIKPDNFLVSATGHLKISDFGLAFDGHWSHDTSYYHTHRYSLVHKLGLTIEGNAVDRSEGFQGTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X132</accession>
    <name>A0ABR1X132_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004097</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672030.1">
        <property type="nucleotide sequence ID" value="XM_066808412.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041472"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06564">
        <property type="entry name" value="GH20_DspB_LnbB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052764">
        <property type="entry name" value="GH20_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43678:SF1">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43678">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046105848" description="beta-N-acetylhexosaminidase" evidence="7">
        <location>
            <begin position="16"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="708"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="8">
        <location>
            <begin position="168"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="507"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="682"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="512"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="731" mass="80300" checksum="E1BFCD27860EE57C" modified="2025-10-08" version="1">MRSLVLLLALGAAALQPLPPPPESTYGGPAHGLVLNDNFPRTIYLQSDLASRRDTDGLSLIPPSGREFAETFRDDLTRLTQSEWSLKVVESFGKNGSGVFLDLSRDKSANFQLGRSRYVVGNSDTPATPYDIKLDFGACHGLRRRSRLCDPRLHARCGKKMVLPSFLKDLCTYASFFKMSEFHYHLSDNYPLNRGHNETWNEVYSQFSLRPETAELAGLIQRPNETLSRADFEHLQQHCASRGVTVIPEIEAPGHCLSITKWKPELALKKKDLLNLTHPESIPTVKKIWAEFLPWFQTKEVHVGADEYDSTLADDYITFVNEMATFMNETAGKRIRVWGTDEPSENVTISKYVTIQHWQYGQSDPVQLQQAGYDTLNSEDWWAYMSLKNDHAPILPAPYPQFYNETRTVNFADQEGWQWQPALYNPVNTTEQVSDDASGNKGAILAAWNDNGPDATTQLEAYYAMRRGIPLVAARAWSGARGAQLDVSTLDDSIDFLSAQAPGQNLDRRSDFTSWTKDQTAGGSDPVTLGRGGGGSSKGMNYTMTLSATGPFVLSSADVTLELSETNNHLVFISDGWAYPLRAVHEQDGFDAGHPGRIWANSTRSTHEPVAIAVPAEITITGDVVGGCRVWVNGSFAGRFEVYVFGGKNTLFSWSQMAFVAPLETVAGTGLQSIKLESAVKAPDGGGGTNTTAPPAQSQGGLSSHQKLAGQLLLLGIAWCCGVLAVNSYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X294</accession>
    <name>A0ABR1X294_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004503</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672436.1">
        <property type="nucleotide sequence ID" value="XM_066808818.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041878"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007255">
        <property type="entry name" value="COG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04124">
        <property type="entry name" value="Dor1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="444" mass="48180" checksum="2CAE0864CA7F2E6F" modified="2025-10-08" version="1">MADLLYDLLRPAGRDQSSAPNAEPAALDYLTSLASSPLEAIESEQPQALAQTSHSLLLSLQALSKRSHKSIIESASNHANLRTALPALATSTSDLKSGIPKLDNEAVRFSTTYHKSGENEMLNSRKRALLLSRNVERLVDVLELPTPLSSAITTGSSSAAANYTPALDLNGHIRRLHSLYPESHLVVSVSTQAEEVMQTMATNLISSLRAPGLKLASALRTISWLRRVIPELDPAGATGNGGGLGALFLVCRLATLMNMLAALEPLRDLADQEKTRQQQSSSGSAWSGGQQTERYLKRYIEIFREQSFAIVSMFRSIFPANNGSTSVGATKEAELDPLQPIPSALSTFPFHLVEMLMETLRIYLPNVKDQTSRDSLLTQVLYCAGSLGRLGGDFGVMLASLDVGQEQEEEWVEVVKRQRIMAGRLESIVGSKDNKSNPDIAIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4J3</accession>
    <name>A0ABR1X4J3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673207.1">
        <property type="nucleotide sequence ID" value="XM_066809589.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042649"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4130">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="16483" checksum="84D7B15AAFC453BE" modified="2025-10-08" version="1">MEALGAAGSIVGILGFIGQSVAGIAKLQAFFDGYKKAPQIAETLQSDMASLQATLMDVKAVVQHLENQAWDNITEAVKTNLANLTEFARQCSDDIASWVQVTAGLNPKHKSGFKSFFRKIKIAFSGPNTLRSFEADVAKHRQNISNALATLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4L0</accession>
    <name>A0ABR1X4L0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CorA-like transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673254.1">
        <property type="nucleotide sequence ID" value="XM_066809636.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042696"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058257">
        <property type="entry name" value="CorA-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26616">
        <property type="entry name" value="CorA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CorA-like transporter" evidence="2">
        <location>
            <begin position="2"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="33210" checksum="A1F3DA5B3843C6E5" modified="2025-10-08" version="1">MERSKINNKSQLDRHYTQHLVNKETDPRVRHLFLTAGHSTAPLNCTLEMFQFLCTYHQVSPGFLDLICSFGRELGGFNVFHHMHILHERFSSTRHPSTAIREIGRSGDELRVGYKLFAMEQQEPEHKNKWVMRQTATYHTLDLAKWKAFWITVKANNVVRERTDEISTNASDSLAAEALSRSLLTHQVMFNWCTEGWAWYIAEVDDTVEKILRPLTAADIPPEEGSLDPHQYIAKTLSFQREKGLDQVSEKTLPRSAGGLSPVQPRNEIARTETQHTTRSGQEREAQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X861</accession>
    <name>A0ABR1X861_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001926</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673537.1">
        <property type="nucleotide sequence ID" value="XM_066806241.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039301"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF193">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G00940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8091565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="60966" checksum="469D848482D31379" modified="2025-10-08" version="1">MVEPTSDSARVLQFGSIEDESYELQDKDKEFALRGDPILEFRFGDLSSSNLELHFGDDWGRQRSRSRAISESRSRPVSSIYQDQFPTGIKLVFILASMVLVQFVLMLDLSIIATAIPSITNEFNSLLDVGWYGSSYQLASASLQPMTGKIYSNFKSKWHGLSPVGSAGLLTGGLTIVSACLPKQRQPAMLGIMIAIGQLGQASGPLIGGAFTEFVSWRWCFYINLPIGGLIAGFLFFVHIPDRVEKPDKAKILSTFASTMDLVGFGLFAPAAVQLLLALQYGGNQYDWNSATVIGLLAGGAGTFALFFYWEYTKGKSAMVPLYLLRQRTVWSSCATMFFNIGVTNIISYYLPIYFQAVEDASPITSGVDLLPNILVQIAFAMVSGLTVQRFGHYWPWVVIGPTASAVAFGLMSTVRPGTASANRIGYQILAGFGMGAGTTMPFVVVQNLVPLAQTPTAMAILLFCQNFGGACFLTFASTVFNQSLPKAIATYAPGANVAEILATGATAFRHVVSSSDLPGVIMAYSVSISYVWYLVCGAAGGALMTGLFMGYRDIRKTGNAPAAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X891</accession>
    <name>A0ABR1X891_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dihydropyrimidinase</fullName>
            <ecNumber evidence="6">3.5.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_001956</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>5,6-dihydrouracil + H2O = 3-(carbamoylamino)propanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16121"/>
            <dbReference type="ChEBI" id="CHEBI:11892"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15901"/>
            <dbReference type="EC" id="3.5.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.2" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673567.1">
        <property type="nucleotide sequence ID" value="XM_066806271.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039331"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01314">
        <property type="entry name" value="D-HYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011778">
        <property type="entry name" value="Hydantoinase/dihydroPyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050378">
        <property type="entry name" value="Metallo-dep_Hydrolases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647:SF1">
        <property type="entry name" value="COLLAPSIN RESPONSE MEDIATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647">
        <property type="entry name" value="HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="8">
        <location>
            <begin position="61"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="341"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8091595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="556" mass="60673" checksum="CA2A90B41F8E0654" modified="2025-10-08" version="1">MDPDTESRNLDLIIRNGRIVTASEVLTLGVELGVKNGKIHCIGQSLKAGPETEVVDAQGAYITPGGVDSHVHIQQDNSPTGDTWETGSRSAIAGGNTTVIAFATQKRQEESIWTALEAYHGKATGNSYCDYGFHLILTNPSETVLEAELPRLVNEEGISSIKLYMTYEPMKLGDGDLFNIMMKARSLGITTMIHAENSDMIEQITKRLAKQGNTGTFFHSIARPQLAESEATYRAISLAEVTDAPILLVHMSAPEAVRHVREAQARLLPIHAETCPHYLYLLSDRLRSGPNDFEGAKSICAPPLRHDARDLEAIWMGLAAGTFTVVSSDHAPATFDHPCGKMKGLQMPEDTEGSGGSNGGKSQRARGDFRNVPNGLPGVETRLPLLFDRTFDPARPGGGADDDKIRIPLTRFVEVTSTNPAKLYGLGGRKGSLLPGHDADIVIWHPEEPPLVAVSEADGPPSSSSENEPRGKKKITITKSVLHHRIDYTPFEGIEVRNWPRWVFLRGRRVWDRDGGGVVGEKGDGVFLKRGKSTILTGQMRRTGIGMMKGEQAYWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8P0</accession>
    <name>A0ABR1X8P0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial protein Fmp25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002186</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673797.1">
        <property type="nucleotide sequence ID" value="XM_066806501.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039561"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053245">
        <property type="entry name" value="MitoProcess-Associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47563">
        <property type="entry name" value="PROTEIN FMP25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47563:SF1">
        <property type="entry name" value="PROTEIN FMP25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="276"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="340"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="64608" checksum="B05C006E7B00FDCD" modified="2025-10-08" version="1">MSAFKVAMRGTPLACRALRPTTTPVRLQSLRYASSQGGGKKQGGGAGKFLGGMAAALLGAGAFVAFWPATQKEVAKPAQARIEYEKARPRPESKEDNRDLISSQHLQVKKSWEDPGVYAWGSNEGRVAAPDLTDSAIKTPRRIKYFDGQLLRDIKLDREFGAAITEKGDLVQWGTAFSKEDPQPKPTLKGKDLTKLAISRDRILALGKNGTVYSIPVSGSDQASAAKTESSSWTSFWSSPSSASYRKIQIPSLGWGEGIADIASGLEHALILTTKGRVFSAASSTSDYPSKGQLGIPGLTWTTRPQGPYDAPHEISTLKGFNIIQVAAGDFHSLALEKAGRVFVFGDNTSGQLGFEAEREIPYVDGPIPLPFSKIYAGTAQVPRVTSIGAGGNNSFFTVEATKVASQSGQSDTSVALAPARDLGRVTADTWATGAGIYGSLGNGKWTHVTLGPTKIKPLSGLYEWDEHTKSIVPIRLARLSIGTTHAAAVMANETSVGATTTSSENDINWGADVLFWGGNEHYQLGTGKRNNVNTPMYIGPLDGGLGMNSRAVRVRSTGCRSHREPRHDLDPTARAERLAWNRGSSADASSLLFTLEHETDSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8V1</accession>
    <name>A0ABR1X8V1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673777.1">
        <property type="nucleotide sequence ID" value="XM_066806481.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039541"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="455" mass="49270" checksum="575D9B4A4202129B" modified="2025-10-08" version="1">MGSRKSRRSACDLCRLYKLRCDRDERHGKSCGRCQAANQACEITLGRSSQAPNNGDSKERENLLNDSSSTATASTAVAAPRTNLDLAHPSGQLGRSSLSTSGGGATAGSMASLAERVSCEDSSPAFPDHGNPMDYANMDFSMPIPGFDSGDFSFMFPNTQSGLSNPGTAKMPDINNSELQITPGAIGLEQPWSELHSSVDSAPGPPRRTMEDNEHPAIDSKSLTQLSLEIIEDYELLRTSSPLKGQPETVPHHCSSTEQHRPFNRMLNQASKLWDIIKSMSASASTTEGEVGFSASSAAHTAMPKRTDQVLIMTLITTYAHLMRNCRGIFMRLLLALQSDASAKLILPSLQFGTFQLSNSLPIQVKVLIDITSGMLLRITNALGINPVGVTAGPPTPASMQEEPETKLPFLMDPIAVSLRDTILSQEYDLPENEQHMSLHGIMVDILHLVDQKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9W7</accession>
    <name>A0ABR1X9W7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674220.1">
        <property type="nucleotide sequence ID" value="XM_066804447.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037507"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="119" mass="12953" checksum="92331A27F10D0394" modified="2025-10-08" version="1">MQRHQDRPAFAAAGRAKAVRTLLDPFDLLVNGRLFVGPPRQPRAQREVPLAQIRSYVKYDYFGGDDEDDAAAGCPGSGSGGSSGDGNEDKAGPEQWEFFRAIKDHTSRRYATTWAAAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAM8</accession>
    <name>A0ABR1XAM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000352</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674440.1">
        <property type="nucleotide sequence ID" value="XM_066804667.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037727"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="264" mass="28297" checksum="C53AD016699503E0" modified="2025-10-08" version="1">MDLRRQHTDMEPAVSSAHPGLEVEVYPGLEVQPHSAKELSQTDNTQHHQRTHPGVPKSEETNIPKVTTDKRRRILGLTTPTFWGLLVALILLIAAAIGGGIGGGLASQQHSSGSSAAAAAPTAATTLAPGQQPTGGGGGTLTVTTLLPLMQPDATPKDNCPGTNHRRFDSGILLQGKTVNRTFEQQCDTNYADGPENRGLLDLLAFYAQNFEECMKWCAQYNQQVQQQKIRASLNRGTGGADYCHLVSIALMHKSGLTLPWAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAR6</accession>
    <name>A0ABR1XAR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular serine-rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674519.1">
        <property type="nucleotide sequence ID" value="XM_066804746.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037806"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF17">
        <property type="entry name" value="CUPREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046695512" evidence="2">
        <location>
            <begin position="18"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="249" mass="24081" checksum="A726CEDA183D6192" modified="2025-10-08" version="1">MQFTTFALSALMGLAAAQKVHVVSVASTNNSLIFMPDNLKAAKGDMVQFQFRGGNHSVVQSTFDAPCMPMSMAGAAGNSSGAAAKGIFSGFQPVAASKAMGMLPTYTIMVADEKPMWFYCSQGKHCQAGMVMVLNENTSANATRSLANYKALAKKATANVSPPTPAGGAAGGSAGGNSTGGSGSGSGSGSGAGSGSGSGSGTGTGAGTGSGTGSAPGSQSSTPTTAGASTATISTALSLLAMAAASFML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB89</accession>
    <name>A0ABR1XB89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674632.1">
        <property type="nucleotide sequence ID" value="XM_066804859.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037919"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="176" mass="16211" checksum="1E55276C596ABE32" modified="2025-10-08" version="1">MHPFSMGIMGTFCFPPVKGSNTGGGEETTNEGGGSGSGVGGGGGGGRLNNDSAVGGLGGLAIGGLGGRAGLGAAHAAGLAGGGSDDNTAGDGGGSAALGGRGRVGAAVDDGGGAAGSGRASTADSAGGSGDDATDSRGGIGDDGAGELSVGTSGQGEEGHGELHLEVGLWWWYYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBE8</accession>
    <name>A0ABR1XBE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">PAP2 superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_000726</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the type 2 lipid phosphate phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674814.1">
        <property type="nucleotide sequence ID" value="XM_066805041.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038101"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03388">
        <property type="entry name" value="PAP2_SPPase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF28">
        <property type="entry name" value="DIHYDROSPHINGOSINE 1-PHOSPHATE PHOSPHATASE LCB3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="531"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="10">
        <location>
            <begin position="112"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="413"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8094041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="556" mass="61367" checksum="E280661120CCD1B2" modified="2025-10-08" version="1">MCSTHTNGAAVSADSKKLTAKASDGEKPPVIDAGLRDLDHYKRALPPWRYNLRQWALPLIRWETPYLAYLQDTLRTPALDSYFAITANLGTHTFFMVGLPIMFWCGFESFGKGLVRILALGVFFTGFIKDFFSLPRPLSPPLQRITMSGSAALEYGFPSTHSANAVSVAVYGLLCLHSPDNMMQPNIKLGLEILSYFYAASIIFGRLYCGMHGFVDVVIGSIMGAVISLGEFYYGPALDMYLYARPFTTVLCVVLFIIALVRVHPEPADDCPCFDDSVAFAGVMIGLEIGTWHFAHSPHGLIRFDLEALGWPVVILRIVTGVLAVFVWREAAKPVLLRSLPHFFRIIETWGMNLPRRFFTPASKYKNIPLRLQVDNVLPNVSDFPNFVNNIRKGGRGRSVSIGPQSAADAYETLAYRDRRRRESNTSNTSRGLRGKESVASLRGASPSPITPSDEKSGGAKSSAISSGHHNKLGDYERMMGEGTIMVTPPEQEGDDPTLVIGSQDELSEREVFAQLIKPRVRYDVEVVTKLVVYTGIALLAVDIAPLMFTVIGLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBS7</accession>
    <name>A0ABR1XBS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein serine/threonine phosphatase 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674869.1">
        <property type="nucleotide sequence ID" value="XM_066805096.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038156"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF589">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="6">
        <location>
            <begin position="169"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="463"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="612"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="620"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="638" mass="69562" checksum="C4872B6E861F3344" modified="2025-10-08" version="1">MSFRPRSSKRWSLKRLLWASCADQPLVLGFIANYVETQSRRAPSLHTSQPIKSLRRNPSRCLSVTRKLSDTSAAEPGAPEEPPQDPASTATPQAPRRGFHNYFVTHLPSSSLHPDSRISGPHHRLPRSAATRYVPTPGSSPAPAAAPPNVSANRDLTVVRIPLRSAKHHFGVAESRGQRPHNEDTNQAGTIDMPSFAKRTPISLVRSAMNKSGEATPADSAFGDPQIFYFAVFDGHGGDQCSSFLREELHGYIEEAASEFELKSSLKANKKNARESQLVPTPMMRDKDAGGAKQLSNVDLKGPQEVKQEAEIPKADKHGAIKELDNAEAMAGSKPEPAEGNESKALRLQKSLVKEYKDAIGGYFRRFNPPHFGLRREPDTPEPPVTIEAVLTYAFLRADLDFIRAQARKPDPDDPYVSDAAVNNDEILGAPHHAPPSGHRIGGGKRFKGGSTASIALISTPTPAPFWHPAATSTPGETLTTDHHPSSPSEAQRLRRYTASFITDSFGEERIQGLANSRAFGDMGSKRLGVSAEPEITRTEIGQAQYSFIVLMSDGISGTLSDQEIVDIVKEAKTPEEGATNVVNYTNEVTSNGDNSTCLVVRLGGWERRSEGGLGSLGTKEIRDYRRNEALDPRRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCE7</accession>
    <name>A0ABR1XCE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_001060</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48096"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11991"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61897"/>
            <dbReference type="EC" id="2.1.1.319"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:48097"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11990"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65280"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:48101"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675148.1">
        <property type="nucleotide sequence ID" value="XM_066805375.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038435"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049482">
        <property type="entry name" value="ANM3-like_C2H2_Zf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF116">
        <property type="entry name" value="PROTEIN METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21137">
        <property type="entry name" value="ANM3_C2H2_Zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 18" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase 3-like C2H2 zinc finger" evidence="16">
        <location>
            <begin position="69"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="15">
        <location>
            <begin position="253"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="17">
        <location>
            <begin position="357"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF21137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8094375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="559" mass="62854" checksum="46E76DFF1AA18E29" modified="2025-10-08" version="1">MSRPSRAEDPVSDSESSDSREDEEGWNDVEEDEETQEVISLLDDRVFPDVVAMLAHCKEAHSFDFLALRQKLRLDFHGCVKLVNYIRHRVHEGLPVSEQDIIKELIEDDQYLKPVLEDDAVIIGLFDLPELEPEQAPASGAESSAVDDLMKRNADLQEEISRITAQFESYRATVSETLDQRWGDAAEAEAAASKDKALTVAAGKKKPEDASKYYWESYATNDIHETMLKDTVRTESYRDFIYNNKHIFAGKTVLDIGCGTGILSMFAAKAGAARVLAVDASDIIDKARENVIHAGLSSTITLIKGRIEEVTLPVQSVDIIVSEWMGYCLLYEAMMNSVLWARDRYLAPDGLLAPGSCNMWIAPVADSEWIQDNYNFWRDVYGFDMRAMQAGIWDDVRVLHWPSSALCGKPAGFKMLDLYTLAEKDLTFTAKFRMEITEDIDALDGFLIWFDNFFAPSRKDNETVNADSVADDWAKAPTSEKERVAFTTGPFGTETHWKQGLLVCKPKKDEPTAYKKGDMLEGEVTFAPPADMPRGLTISTTWKLAGSEQKQHSQSWDMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDZ7</accession>
    <name>A0ABR1XDZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675674.1">
        <property type="nucleotide sequence ID" value="XM_066805901.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038961"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="10752" checksum="F31855079C07A2CE" modified="2025-10-08" version="1">MRSGYNLGHALSFRYWRLRWRDLELWAWLVRGPLNNNALRLFETNPDGVPGCGRRAWPGARGALQRAYEYYQEYKKQKRDECDTNRTDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ38</accession>
    <name>A0ABR1UQ38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conserved glutamic acid-rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660452.1">
        <property type="nucleotide sequence ID" value="XM_066819567.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052627"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018822">
        <property type="entry name" value="UPF0646"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10336">
        <property type="entry name" value="DUF2420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="761"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="796"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="815"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="833"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="857"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="874"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="913" mass="98746" checksum="AA52561FAF3EA470" modified="2025-10-08" version="1">MTGEEMEIVAGSSHLDQVEDIDIDLNYTSGQMDDDMMLGDYDQIADGQHSPEVGDEQMAEGDDASYGMVDADEIDYNDAADPANDPDIEIGGTDDNSWQPESVAMVQELGDAQASVDEVDFAIVADANDVEVQDATEISSEVWLEGQSSNVADLPSAAAQTSDTSEAQQDPSIAIETITSNAGHTEASRGNLSPATSNNPATIEVSSTAPQEQETQQAGAQEEHQYESHVDHQNEPHEELHEEYQEARHDEYQDVHQDEHNGEHLEEYPEEYNGGFEELTKEFGEDNPEQEAAETTASEVVGADATGEGPEPPTDLHHLESGEADRGDYVENAQATDEWAAENLGVSDEVQAGVDSHETASQAEQPLSSQNHEAEPVTQSSSPIANSASAEDDNAGESKTVGPLPHPQITATEDPSAIAARYDIVVQYGDSDYQLFAKSTEDDPNRYFLSDRSTLDLPLVDFLSSIREVIAQELSPLDELVMSIDGLGVEFAETTTRDFIERYTFGEMLVLYDNLARNDDADFKPDIHIVLQVRPNCSQRLAALVDQANSGRGLSDVALYRDSPQLNDDFDEDFEEYEEDEALAMTPEPENDEYHDEVDAEADNDNQPEEQQVLEYTEDDEQEQHSDTQEVNGQSGDTAKSPGKDETEVANVDESEVANVDEAEVGNADDDLLNGNDELDLGPTKQGNTPFFLSSPIVPCTGNFSECLCDDCFLFDLSDGGDDHQPGLSSLAVDQSCFHGTPSASGHASQSKVYQRTVSFTKTSDANSKRSQDQPTTNETQDHPINTGDEPLAQNGHGSDASSHNTSVTATLNGDDQDEIDYSDDEGGDDQDAANSIAQDEVTSQENTAPTKSQTAVDDEITWESEDEDAGEAANTTPSNLSAQVSPTTGKRTRSASSAADDEAPPSAKPRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT07</accession>
    <name>A0ABR1UT07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660664.1">
        <property type="nucleotide sequence ID" value="XM_066818476.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051536"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="76" mass="8640" checksum="F6020FE4B3353DAA" modified="2025-10-08" version="1">MSSLVNPHRAKRGFPALQAMLEDFEAEMDYGGMWYPKLFWAYFLGPRGGLDDFSIHQVWREALDPSLFVSISLATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTM6</accession>
    <name>A0ABR1UTM6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660877.1">
        <property type="nucleotide sequence ID" value="XM_066818689.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051749"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF310">
        <property type="entry name" value="FATTY ALCOHOL:CAFFEOYL-COA ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="298" mass="33388" checksum="56C1B84B25BA639D" modified="2025-10-08" version="1">MQESQVDDRHADSQHLVGLDDGGLTAACKEEAGDALIMSQNGGFHQESAMEPSLFYMPQQMYAKLRQELVSLQGGTDVSGNDIICAFIWRSILRARTAVKSALQQQQQQEAVADLAETMATLAVPFDARRNLSRVLTVPYLGNVNFEHIFTLPLRTLISPETTVAWVAKMIRTHVTRQTHEEVLLEAYGRLRSVAAYDPRRVQIRASRLSTASTSVGILSPMTLPFNGTCFGEPLFTNGGRPEAFRPMMGTCNRGYRTCFVIPRKQHGGLEFVMTLSREEREFLQEDDEYNRYAFSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTV3</accession>
    <name>A0ABR1UTV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidase signature enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660954.1">
        <property type="nucleotide sequence ID" value="XM_066818766.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051826"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="220"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="679" mass="76102" checksum="FD5A9D5A44E67E31" modified="2025-10-08" version="1">MTKKVLALARHPNNEGKPGPDFQLLHPLCPPTGWRFTAAFHRWRDRAQDDREVPRATTVITLGSRAYAIQSTCDFKVPFAAKSAQLKPLACLALPNSTDQGGDLEKEHSHFLENDEFCNSFFETVLLITDKALEKHACNILSGWGCTRFKQISTKTRIPPGPYFYSSSGLFKAWRLFPDDQNAFILSTIPSQHNPQAYEPLNAAAYGSSSLCVAVPSRLPFKTEQKKPLSGWRVAVKDLYHLNGVPTGCGNRAFRVLHSETRASSSSYVQLLIDSGCVIVGKTKTVEFGASQEVTGDWSDYFYPFNARGDGYLAATGSSTGSASSLAQYPWLDITLGTDSGGSIRDPAVANGVYGFRPSHDGKPISDIFLPCAEFHTPGFLGRSSDAMLGFGRVWLQNAPILPPSSRDTEPRAIVNCLTPWRPVRILLLEDYRSDRDAVQNIADNWVASLARWLGAERVLLSIGDLWDETKPEADNKGFYETFSNTFIDITYSEYWTYLSNFRKEYKERYNSDPYVCKVTKYLWDKGRMISDVRKQELLAEVAMHNKWFLEHVLNDNSSIIVVPRYSLAYRDEYLPYPPEDRIFEGFDSNLHASFCGLPNIIVPVGQCAYMSKISGNQEYFPVSLSIIAPRGMDIGLLSLVDDYLKENQRPTSVLTGPTAFDPLLFQKNDTDSVSRKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU81</accession>
    <name>A0ABR1UU81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661072.1">
        <property type="nucleotide sequence ID" value="XM_066818884.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051944"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="87" mass="9805" checksum="408438A2C7434032" modified="2025-10-08" version="1">MDCLSVIDPVIRRTWDGWTTGRCVLVVNGFDTPALTGSIKQGLRKDVDVRLNDFVTPIMPHHVVSEFTTAILRFLRTLPCYYQPGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUX5</accession>
    <name>A0ABR1UUX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase subgroup</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661096.1">
        <property type="nucleotide sequence ID" value="XM_066818908.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051968"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="299" mass="33512" checksum="3DD5F645137FF937" modified="2025-10-08" version="1">MSQHNAHTKKTYTLASGDKMPAIGLGTWQSGKGQVGEAVKAAIGAGYRYIDTALAYGNEAEVGEGVKASGVPREQLWITTKLDNPWHKKVQEGIDTSLKNLGMDYVDLYLMHWPCPLDADDTSKVYDDWTFIDTWREMQKLVGTGKVRNIGVSNFDITNLEKLLKDPSCKIKPAVNQIELHPNNPSKSLVRYCGEKGIHCTGYSCLGSTDSPLYKDPTLLKLAEAKGKTPQQCLLQWGIQNGWDVIPKSVTKERIEANFDLDGWWLTDEEVDQLDNLKDRFKVCGDDWLPIKIFHGDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVU5</accession>
    <name>A0ABR1UVU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-ketoacyl synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661655.1">
        <property type="nucleotide sequence ID" value="XM_066819467.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052527"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-ketoacyl synthase-like N-terminal" evidence="2">
        <location>
            <begin position="62"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8063056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="128" mass="13313" checksum="5B67EDC13974D014" modified="2025-10-08" version="1">MAASTSTSSFPFGATPAETPGETPYGQTPGESPFAGSPPSSATSVSAADSDDMTPTATDPSAIVGLAFRLPGAKSIPQLWDNVVTKKDLQKKMPEDRFNVDAFYHPQGTNKGTVSLIILHNRAGSLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UW32</accession>
    <name>A0ABR1UW32_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Glycoside hydrolase family 31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_015214</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661716.1">
        <property type="nucleotide sequence ID" value="XM_066819528.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052588"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF67">
        <property type="entry name" value="ALPHA_BETA-GLUCOSIDASE AGDC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 14 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="17">
        <location>
            <begin position="124"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="16">
        <location>
            <begin position="288"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="18">
        <location>
            <begin position="750"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="462"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="537"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8063117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="946" mass="104422" checksum="B968715E2FD36FDB" modified="2025-10-08" version="1">MSLSPIGAPQSNPTATMMLPVAFAGVAAAAAITNRQLPTSPDPLSACPGYTASDIQQSANGLTASLKLAGMACNAFGRDIEELKLTVNYDNENRLHVKIEDAKSIAYQVPESVFPRPDASASVSAEDAALEFSLTVSPFAFAVKRKDSGEVLFDSGAAPLVFEDQYLRLRTSLPRSPNLYGLGEHTDPFRLNDTDYTRTMWSRDAYGVPYGTNLYGNHPIYFDHRVASGTHGVFLLSSSGMDIKINHTSDGQQYLEYNVVGGIVDLYFLAGPTPTQVSQQYAQVAGLPAMMPYWGLGLHQCRYGYRDYYAIAEVVANYSEANIPLETMWTDIDYMYDRAIMTTDPDRFPLDRVRQYVDVLHERNQHYVVMVDPAVAYSTTRDKNQSYGTFNTAAEKGYFLYKDGAIFQGVVWPGVTAYPDWFHPGAQDWWNAEFVDFFSTDKGVDIDALWIDMNEAANFNNFGEDPLETEKSGGFPPQRPALRDQPWPIPGFPAEFQPGSSPYPPDSWSYAPPWLAAPSDPNHGKRQAASVSRKRQTTGSSAATAPTPNAPIGFPRSSDELLAPKYQIQNANTAAALGGLSNKTLDTDIVHYDGHVELDVHNLYGSMMSTASRNAMLARRPNRRPMVITRSTFAGAGKHVGKWLGDNLSQWDQYRFSIAGMLDFAALYQVPMVGSDICGFGGNTTETLCARWASLGAFYTFMRNHNGDTSIPQEFYQWPLVAESARKALDKRYRLLDYIYTALHRQSVDGTPSLNPLFFIYPGDANVAAIEHQFFYGDSVLVSPVTQENETSVSAYLPDDRFYVFDTWEKVEGAGAEVTLDNVSFTDIPLHVRGGTVLPLRVKSGYTTTDVRKEPFNLVIAPCRDGKASGSLYLDDGDSFEQKAVSEVAFVYDGQLQISGSFDYEGRVARITVLDSGGCDGCEYDAERRVAVYQVDMKLGPVTLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UX26</accession>
    <name>A0ABR1UX26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661184.1">
        <property type="nucleotide sequence ID" value="XM_066818996.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052056"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="343"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="783"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="803" mass="91983" checksum="056D1E00FCFA097D" modified="2025-10-08" version="1">MSNPVVATAEARDYEQAHHPPNHSFSQAVPSHSTVGHASEEPRFLPLTHSQPRVVIHSYDCPDVETANKHESLYISSDESDACMRDRDDIENGPQSTPASQISWTSHHLEAGPDSPTVISDAGIQQFKGQRREGVSVASTSVTSHATLEDQLFAARQLTKHPQAEPWKKDMGFIPKKQLDNITTEESVYQEIRKHFAHSFDEVKLREIATYVCHEKKVIVGDGRAKLKSFKPVFALLVMFNKTSEILDILGEDVSDLDLPLVDIADGSYGRHRIGRRSRIHKAQSDDTNIHLWCFSKWSRVESESFLRYQWMMLAPFFRESEYNDVQHYELHDSHILPWIDRAGDEYFEHQGGFGMVFPVRIHQEHHSFSDTAACKRGFAVKQLMHKDPAKFNREVGILQKFVGHNAHEHIVALLATYEHCGKYHMIFYRAQGDLFKYWKKVNPDPTFNRDTVMWVARQCKGIADGLVQLHRHRTLPKSDEDDGEYLVQNRETVQQRSAAKKEYILSKSKLGKRKRATDDIGVEQELRARQGQWQFGRHGDLKPENILWFQGPQGSNGTLKIADFGQAELHEWQCKTRKRSEVADTMAYRAPECHFEDGKFRQSSDVWSLGCLFLVFVAWTLGGAELVKEFAKVRSSYDEYWGVSSDTFFEISRLQEQPDAWSVAVKPAVVKFICQLHSHPNCSAYFHELLDLIFKKMLVVEMETQNRRIACHQVHKRLREMYEQCATKKGYATTPTPWKLHDLTMPESSSPIHVRPLMVAKGGIVEVLANNKKAQIGLTLREGKRNPGARGDHRRPPRSKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1D3</accession>
    <name>A0ABR1V1D3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8064993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661747.1">
        <property type="nucleotide sequence ID" value="XM_066816055.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049115"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8064993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="381" mass="42198" checksum="FDCE44D0E0F4848D" modified="2025-10-08" version="1">MPAKKFDPPFPPQKHTPGYICCYSWTKRKPNRCHQSTIPCFPSLSLSGALHSTWPGSPVQVPSSNFPGSWSPVLAACPGLLQGPYPNTDKGRRREEEEEEVEVEEKQQQTTVPTGRRTTNRSSDLLTAERRAHFRLTYVCNTLRLGPLNDPVKTLKLETRQWRLAHSSGPIYGTAPVSLAAFPSDNREPPHPYPVQPPASSSVSLRDDGGTDSQPASQPAAAAPVAEQPADHRGKSDWERGSRRPFTTQDRSDFWSTCFHFTPNLQYSSSIARHDHDICPLTRYQSVSRLRCSTICPTQAILLRYARFTSTPVTSAPFNPLLQPAEAIGARLSKLNRESVLVVVATTLSRQQQRVSNPAHATKRIPAATLLKTPARESPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1N8</accession>
    <name>A0ABR1V1N8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661853.1">
        <property type="nucleotide sequence ID" value="XM_066816161.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049221"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="4"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="237" mass="27509" checksum="6BF457A57327F3E9" modified="2025-10-08" version="1">MASFHLFPRLPLELRCQIWGLSIPPRYLEICDVRVWPPKDGVITRLHFYVRDIDLEEDEHSYIPTRTPPALQACHESRAYLEGAGGYVKALTGGSRPIYTWLNFDVDTFFTDYDLFPTWAEEGRRIRHLATEYPPIESCYLYMADWYLRCDPVSYYTRIVGPEYLGDTEMTTDNYDSVFRAACKDKIEGVGLSAAEKAEWQPRRWIHGEKCACEDRGILFALELWDTKIKASSTEDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1R5</accession>
    <name>A0ABR1V1R5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome p450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_011875</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661882.1">
        <property type="nucleotide sequence ID" value="XM_066816190.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049250"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="501" mass="56342" checksum="25B97C917F3B3C97" modified="2025-10-08" version="1">MGTLYDRGLGCLHALALLPLLLVPLVIVRRLYFSPASNFRGPFLARVSRLYEAYHVLLKDDWYENLKSLHEKYGPVVRIGPNEVHIADPELCLDFHRRPDLEKCSKYYGLVGTVLGGLSEPQSHLQRKTVIQPLFTGDILARYSAGELNVHMENLHEKLTEAASSQHGEEGTNLTFILWALTNDIMTSYIFGERTGYLAASDLAAAHDATRAYNAIDLATVLRTMPPVKILFNTLPVLRRHSVLGWIDKLISTRLARTSKGDSTTQHERGDESILAHLWHELGGDSHLVTHELAQGVFIGNESLLSNLTFLLHQMLENPRCIQALRAELDTLDIGAYGHQVWRDPKVLQLRTHYVASLRASAPRWHRQPRQSTEPVVCKGDTTIPAMVSISFTPRVLERDATLFEDPDSFVPERWLGNNLETQTLRRNSVTFGTGTRTCLGQYIARHVLKKALVCIVYGFDISLLDADRDSEDGFKYLSTYPKKGKAGYMKVRVASRFAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2E6</accession>
    <name>A0ABR1V2E6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662101.1">
        <property type="nucleotide sequence ID" value="XM_066816409.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049469"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018555">
        <property type="entry name" value="C630.06c-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09428">
        <property type="entry name" value="DUF2011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="314" mass="35302" checksum="EB598E2939840C07" modified="2025-10-08" version="1">MFDIPEAKRVRREDLYSSASSDADDDDLMGQDGQVDTELRERLRAQLAGLLDLDILSPSSLPAPGVADTPAQKSGTAVASDEGANGPPAGTNGELLATDESNPDEVAFTFRLFRDEEPSHTVVIKQGDETQVGGKAEFVVPRRPQSYYLAGKPDQETMAQYKFAAVSTEYLLANAKQRKWGLEKPWRVTKITVTADKNAKTLPDAGGAEDTTMGESKKTRPGKKRRVLLRTREKAKREKEEAAKKKLADKEEHLKEKKKRLNRAKKLKRREKQRKRKAPVEEVRMNQARERRVRNENGSSRIYSMCCLPNMYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V412</accession>
    <name>A0ABR1V412_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012668</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662674.1">
        <property type="nucleotide sequence ID" value="XM_066816982.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050042"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="13"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8065921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="495" mass="53952" checksum="9F506E3660C08704" modified="2025-10-08" version="1">MAKHMVFSKTFLTSIFLGIGGFLYGYDSGIITPSLALRSFNKYFGNPDPSSRGAIVSIYQAGAWFGSASVVTASEDARPSSLDASGGVIGAAIMAGATHVAMLVLGRLLVGFAVGTITGVAPVYAAEIAKTHERARLTAVNQMMVAWGFSIALWTGVGEGKWKNPNQWRLGFAIQGIPALLLAAGVLFLNESPRWLLLKGRTEEAEIAFRNYHCGRAEDDQWCRSEFAMIQVNIAEEIRTQRELSWGDLLKTPAFRRRLFVGSFVWAAAMLAGISFVQYFQTAIYATLQYDESQQLLISGLYGTVGPIACIASLFFVDRVPRKTILVSSSALLSICFLIITVIAAVFPAQPGIPTNAAAQRGLIACIFAVSANYSALLGPMTWIIPPEVFTTELRAKANAIVQVIHYSISLIITQCSPIALAAVGWKYYIMFVLTNALCALVFFLAYPETKGKPLEEIAELFGDVDTVHWRDMGEVEEKAVVKTGEYRRSRESFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4L8</accession>
    <name>A0ABR1V4L8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661768.1">
        <property type="nucleotide sequence ID" value="XM_066816076.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049136"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="92"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="608" mass="68082" checksum="B1CE3BBE4ACA30EB" modified="2025-10-08" version="1">MVFLPVSSRSRLVTEEVARSYNLSSQIEASVLAEGPVKLIQSSLDHCSKFHSHHNTETPEFTPTRLVDALSERPRVVEMNAPLSEPQPDRRYMALSYCWGGKTQFLLTHDTEQTLKEGFSKDILSATQKDTIELARALSIPYVWIDALCIRQLDHSDWESQAEVMGKIYSGAYLTACAASSSSCEEGYLQRDFVAPIEVPTDPVSDPSGTGGTYFFQPIRWSCGSEFGFYYQAPFSLANSKWNTRAWTFQEMRMSTRLLFFTTSGLHFNCGQYNHSEYYASQVPSYHSTITSVRDAFELKELHQMSNKSKVYDAWYETIVNRYGDREMTKRTDAFPSLSGLAHTFASLLKDDYVAGLWKQELALGLSWVSRKPALKSLETLLSSYNSTDPYIGPSWSWVGRGEVQYIQGGYHIFNVCQELSAECTPKGADKCGELESASLRVRTRVYSARSGTWVFSRDGTNINYIYPGGYGWIDAVLDFKNSHQSDLEDCILIHIGTFYRDKGIPYGLIAHPADDGAHIPASRAGGDAARMPAFHSKRGDLGLQRERRQAAAEYDQPLDGENARFGELKVTKSAQLAVHLDGGDAVRPGSRSSARRQREAGRGAWPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4R9</accession>
    <name>A0ABR1V4R9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_012002</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662009.1">
        <property type="nucleotide sequence ID" value="XM_066816317.1"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04084">
        <property type="entry name" value="CBM6_xylanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18618">
        <property type="entry name" value="GH43_Xsa43E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CBM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006584">
        <property type="entry name" value="Cellulose-bd_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052176">
        <property type="entry name" value="Glycosyl_Hydrlase_43_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772:SF2">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00606">
        <property type="entry name" value="CBD_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047246737" evidence="8">
        <location>
            <begin position="28"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="10">
        <location>
            <begin position="318"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="9">
        <location>
            <begin position="474"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="435"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="451"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8065255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="509" mass="54031" checksum="FB291CDF7E307619" modified="2025-10-08" version="1">MRSATPWASRALLLLGAVLSGVGVTRADNPIVQTIFSTDPAPMIYNDRVYVFTGRDQDGATGYDMREWHLYSSADMQNWQDHGVPANLATFSWANANAWAGQTVQRNGKFYFYVPIRQNSGAMSIGVGDALGKPLVSNNEIDPTVYIDTDGQAYLYWGNPNLSYVKLNADMISYSGGINKVQLTTAGFGQRNGNAQRPTTFEEGPWLYKRNSTYYMIYAANCCSEDIRYSTGPSATGPWTYKGVIMASAGASFTNHPGIIDYKGKSYFFYHNGALPGGSGYQRSVAVEEFAYNADGTIPTIKMSTGGPAQVGTLDPYVRVEAETMAWSQGVKTEAASEGGMAVSYINNGDYIKVCGVNFGSGAGATSFSIELRLGSATGTLVGTCTVAGTGSWSTWATVTCPVSGATGTKDLFLRFTGGSDNLFNFNWWQFSNGSGSSPQPTTTAGGGDAPAGTTTTQAPAPTTTANNPAPAPNCQALYAQCGGSGWNGATCCSQGTCKVSNEWYSQCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5D8</accession>
    <name>A0ABR1V5D8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663151.1">
        <property type="nucleotide sequence ID" value="XM_066817459.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050519"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
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        <location>
            <begin position="456"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="529"/>
        </location>
    </feature>
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        <location>
            <begin position="533"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="571"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="625" mass="65222" checksum="64322E1439A21566" modified="2025-10-08" version="1">MSSTSPSFGSNNPFRRKTGGPLPQHHDGRHDPIQTKPKKIVKKVRVQSPPPSSPEDAVPVTTYFPPADYGDDDDDDDRFDHVDSRNGRNAINEGDGVDPFSGAQTEEEEEEEEEARTETSDDHTLPRAPPNPFSRSPGDVEQSVPGEEANSAPGSKGALDVNSFKRLLLTGYADNTGAAGAAAGTSLPGPTGTWSGSSPLPTPNHDGASVTDASSVSRQSVADAILDTPRTSHEISEPEEAGERRSSHLTSPLANIQSASGRKKPPPPSSRHGKLIKIELGSEQRPSTPRRDSEVGVSLDTDVQPTGQQSPLSASSDVNKPLPLPPTRTPADEQSESPFDREAAGKLPEAFSDTAVAANSGPSKPSDGTRSRSESQVSTGTTSSVRKPAAPPPRRHGRSDSKPPSIMANPADEEAPRSSMESNRSRADSLRPGSSANAGLAAPIPPPPRRPSHNRSGSSITSPTSVSSPGSIDGGRLPQGTGFSLFEHPNYGSGMATVTTTKDGVPKLSPPPPPPARQSSARRPPSISSLESGSRKVSREKDGAIAAPPPPPRRSRSNKSSLGNAEAIRDGSGSRSASSGGLERVEGEPPKSLATSEATNIGTGVDILKDLEALQNEVKAAMGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5N1</accession>
    <name>A0ABR1V5N1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase-like (PK-like)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663257.1">
        <property type="nucleotide sequence ID" value="XM_066817565.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050625"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="209"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="558" mass="63727" checksum="EADB9DDA47A8AB1C" modified="2025-10-08" version="1">MQYQSFDSSPEASPAPTSEPSTAIVDTSITSSLESYDTRLDLSQEAEESIHDKLWARRLPDCSDSAKKFIPLDAQEEIINAGSVRRELARKLNLEPTELDELVTFIRPGKSDGDGSPRGTKLFAVLGLIDRLDSILKFKQEGISDCHLPFRRDGRNRLIPRNYRGSFGCFETWRSRTINEFEIYQWYTLTPFLQPRSLGLLDDGITLPWTQYRDVAEGGHSSVYKEGSTYFALKELKSKDPSIFDGECGSFRKLGQHRHLTELLTSFKHKGRYYLLFPWAYGGTLENLWERSQPKPAYAGPRWVAQQAQGLVDGLFQVHHVKSYQKDMEAWKGIGAILDNNQEEDDKIFGRHGDIKRDNVLVFLSEQRDEEGVLKLSDFGLTVFHSNMSRSTDRPGSTRPCGLTYRAPEAEANQPDNRLSPRYDIWCLGCLYLDMVTWLLLGPEGLDEFSDNRSREKGYLSSFNLDIFWKSKKGPQGSLGPPVVKTSVKYWIRYLQGLEDCTDYLPKDRKQCGEVLAKLNEMSKKQVSDGDYLTKKTRRPTLGSILRARVFPKILFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5W2</accession>
    <name>A0ABR1V5W2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663352.1">
        <property type="nucleotide sequence ID" value="XM_066817660.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050720"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="104" mass="11735" checksum="D3DE38961F52D0B6" modified="2025-10-08" version="1">MIILVMLHIEDLSKSQAMCTNAGVRFHTWRHGNGDIHARHPIEEERGSLQPFLLIVETSHLRGTRPGHVTDRAASRHPAQKKTLQSTNAPEGQQRLENNTHTMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6C2</accession>
    <name>A0ABR1V6C2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012316</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the class-II DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662322.1">
        <property type="nucleotide sequence ID" value="XM_066816630.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049690"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002480">
        <property type="entry name" value="DAHP_synth_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337:SF0">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01474">
        <property type="entry name" value="DAHP_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="475" mass="53026" checksum="E370A17E3C22645D" modified="2025-10-08" version="1">MSATNDTNHANGNGSAPAWSPSSWRSKPVKQCPEYPDLKALRKATAELEQLPPIVHPHEINKLKENLKDVAQGKAFLLQGGDCAELFDYCRQGAIESKIKLLLQMSLVLIWGANKRVVRIGRMAGQYAKPRSSPMETVDGKQVPSFRGDILNGYHLDERELDPQRLVKAYNHSAATLNYVRAALASGIADLHRPLNWGLGHVKDPELKAKYSEAVRFLTDMIRFSHTIGADKSSEISTVDLFSSHEGLLLEYEESLTRLMENPAYAIPGEETRMEYYDTSAHFIWIGDRTRQIDHAHVEFFRGIANPIGIKVGPTTPVSDLLELLRTLNPSREVGKITLITRYGADKVRELLPNHIRAVEGSEYKGCVIWQCDPMHGNTRSTGSGVKTRRFNDIFSELQETLQVHQEEGSYLGGVHLELTGDAVTECVGGSEGLDEDDLSTNYTSFCDPRLNEKQALELTFLVADHFRSARADLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6V3</accession>
    <name>A0ABR1V6V3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663681.1">
        <property type="nucleotide sequence ID" value="XM_066817989.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051049"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046459572" description="Secreted protein" evidence="2">
        <location>
            <begin position="16"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="11904" checksum="08893081999CAC37" modified="2025-10-08" version="1">MASSALITGCSLTAAATTTGSYCPRTPAFSPDEGTANDDEGLPRIGSVPIYVMFGGSLPIRYHPIQRGYDNVTREPESHAYTVACWSEYGCGSRLIEHFYHDGIAPDRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7E1</accession>
    <name>A0ABR1V7E1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013842</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663848.1">
        <property type="nucleotide sequence ID" value="XM_066818156.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051216"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="34"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8067095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="942" mass="104957" checksum="58F819EB4943DB2A" modified="2025-10-08" version="1">MASEWQPSPESLSQLAACLKDSLSGFDKAAQKQAELMLSQAKASPDINNYLIYLFSSTTPPAGLQCTVEDLHLIRSSAAIMLKNNVKMGFKQIPESNLTPIKRGITMILEDPNSQMRNYAGNIATELIRRGGLLSWPELLPKLLEMIGNETNQYSTEAQEGAMLTMAKICEDNTKMLERELNGQRPLNFILPKLIQATKSPLPKVRAQALTAINVFTPRKSQAMLNSIDDLLQHLFTLAGDSNTDVRRQVCRAFVQLVETRPDKLQPHLSGLVDYIITQQQSSDEDLACDAAEFWLAVGEHEHLWQSLTPYIAKIIPVLLQCMVYSPEDIAMLGGASDDEDEEDRAEDIKPQFAKKNAARLANGESVDAAQNGNAYEKLASMDDDLEEGELEDIDDGDDANPDERWTLRKCSAAALDVFARDFRAPVFESILPYLTKHLKHEDWPHREAAVLALGAVADGCIDVVTPHLPELVPYLISLLNDPEPVVRQITCWTLGRYSAWAAQLSDPSQKQAFFEPMMEGILMKMLDKNKKVQEAGASAFANLEEKAGKSLEPYSLPIIQQFVACFGKYKDRNIYILYDCVQTLAEAIGPALARPDLVNQLMPALIDRWQKVADDSRELFPLLECLSYVAMALNDSFTPYAQPIFGRCVNIIHQNLEASMQLANNPALDAPDKDFLVTSLDLLSAIIQALDKQKSAQLVKESQLPFFELLTFCLEDPQDEVRQSAYALLGDCAKYVFGELQSSLGNIFPILLKQLDLDSILDEEIDSGFSVVNNACWSAGEIAIQHREGMAPYVPELFQRFLETMTNPGIPKSVIENAAIALGRLGLGNSAQLAPQLGSFAEEFLTSMDEVDPSDEKATAFRGFCVIVEQNPMAMEKSLLHFFTSIARYREIKLRSDTKSGLSEDFQKVIGLYRQLIPQFDTFVNQMQPEDQQTLRTNFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V861</accession>
    <name>A0ABR1V861_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664147.1">
        <property type="nucleotide sequence ID" value="XM_066818455.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051515"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046576594" evidence="1">
        <location>
            <begin position="20"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="150" mass="16027" checksum="317D06F65D54ACA7" modified="2025-10-08" version="1">MKFSSYLVAAVGLATSATAAPVVAKSTDIKSRAPIGSFIWSWYGDDQEENEAVTEEAADAGMVMKRSTGKKARAPIGSFIWSWYGDDQEENEAPTEAAADGAVMKRAKANKARAPIGSFIWSWYGDDQEETDAPTVAPTVASTEVVVDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGW7</accession>
    <name>A0ABR1VGW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664292.1">
        <property type="nucleotide sequence ID" value="XM_066815002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048062"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="469"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="618" mass="70266" checksum="493523880F1C1A4D" modified="2025-10-08" version="1">MGVWSLRNNSLGSHQSLGGLILVDETVFSLALKTIFAPQECSPLNPSLIWVLLAATRVFGSMDILRNYSSFEYERASKSDRFTDEPCDQLYLYSAAHTDGEVFEPTYVESNEHNLAKLLKETRKARKALGRPSASLELVFLPVNKKKKKGFGLKKDEFKRLFEDLGLDESLLGFLVSSRSGWYHVDNGNRRYSFLYKDYMYSLAWSFNAETMETRALVSERSDWKKHSWLKKPKQNQPDEEKKDFDFYLPGLKPLHLYHPLTLAFFGLVDATCYLDGVIITDGYSLGDIELMTKHGAWARKKEELNLKAPKETENDKTHRPKNADKRQEDCRRQDTLIEASKAGQQEEAEESKKEVAALSRASRRIAEAVKEAVNASEHQEYGSAVVLNVEQERQEHIIRQFTLMAESMRGAVKLLRARIHTVNESALSTQKRAKAQANVVSGLIAREDTRIGHTLADRARRDGSTMKVIALMTMAFLPATFFAALWSIPVLEEPGLTKDNFWVYWAFTVPTTIVIFFVWDWLNDKNLWELKKIETYQKAYHAFLKKFQKSNDTRASDGVKNSGAEDHVMEPARNYTHSNLALGGRNSPGREADLEKGGEGDRTSAHSPYPRNASPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI84</accession>
    <name>A0ABR1VI84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664737.1">
        <property type="nucleotide sequence ID" value="XM_066815447.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048507"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="200" mass="21286" checksum="809FA64E926B4BFB" modified="2025-10-08" version="1">MPASTTTAKPVGTKRFQLPALDFHFGSLTDGTNIPPPIPSPVQEVPTPPKTPTPADVGGEKKEPNGAANGPVVKTNISPPPEAVHTTTITGGVKRPADDVPASPTLSSRGSLRRLLSKNLLHNVYDDHASIAGDQSRPPSRTASVVAEERKSKRSSGWFRRLRSNNNSVVEQHTLQPPAPPLFDEAPQKPSGPPLPRYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIB9</accession>
    <name>A0ABR1VIB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8032 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664801.1">
        <property type="nucleotide sequence ID" value="XM_066815511.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048571"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058345">
        <property type="entry name" value="DUF8032"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949:SF0">
        <property type="entry name" value="RE27538P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949">
        <property type="entry name" value="WHITE COLLAR 2 PROTEIN WC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26087">
        <property type="entry name" value="DUF8032"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="261"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="638"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="599"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="720" mass="78433" checksum="9C3C09ED16212671" modified="2025-10-08" version="1">MGVSSMQHHPHHSQGPAPPQHLQHPRPSSIVHQHHQAPPPQSQQQHPSAYSSTHSIQPAYQSTAQAPSAQQHAQDGLPYYHHPSPYSTPGATSGYTSAVKLASFCRFSVWPRSAPQHVRAAPVATAPAVNVLQHAAVAISVNAPAGSSVAIPATCTAAAPSMASQNNMMMSQAPQHPMTQHANQHAQSGMTGSPRHTKMEPQVPQLQRPPSGPLGTPQHSQNGAPPLSTPTGSTPGVNNNAAPGPIPATTPLVVRQDNNGVQWIAFEYSRDRVKMEYTIRCDVESVNTDELASDFKTENCVYPRACCPKDQYRGNRLQYETECNTVGWALAQLNPCLRGKRGLIQRAVDSWRNSNQDPRLRSRRVRRMAKMNNRKAVSTPHPQHMSGPSGPAGIPAPGSMGPGNGSSMGKPGMSGMGPGMHHHHQDGNGQGGDEVGDGEYMDEAHHHHHQAPTGPGSGSGDDVRPAQVFNGYPQPYPSNSASGSSMPPIHDGISGASHHGGAIAARNTRDEDENPEGLFPDIPEAKKRKFILVEDNKRGCRLRVRVTLESVDTKEIPDSFRKSSSVFPRSYFPREMQSPPPSATGSQFFQEDLSDDEVEVEGGRTGRSRGNNGRGRSMVKVPMSDGSDGEVAIPRTRKTTRGKEVRLNDLGYRMAWLQSRVFSGRTIFLQRALDCYRNKTRTAIETVMQDVKTVAPHYETRVGKRKWSERIRKAEKRDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIE9</accession>
    <name>A0ABR1VIE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_011226</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664831.1">
        <property type="nucleotide sequence ID" value="XM_066815541.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048601"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF11">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="54"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8071023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="556" mass="60423" checksum="A6C57D83EB227016" modified="2025-10-08" version="1">MTRPNTPENAGVLTPDENAYSSDRSQDEYNKAEIERLGRQRPEILSSAIVEFGFVTAIIMSMMMGEFFVSGFNIVLPTVGDSLNIPEPSRTWPAEVPSLTTAALLLPCARLSDRYGGRIVFLAGVSWLVVWSLVCGFSQNTNMLIVCRAMQGLSTAAFLPAGISLLGQSYRPGPRKNFIFALYGAFAVLGFYIGIAIGALTAQLADWRWYFWVGAILAFANAVIGFLTIPKDLGQDGDAALAMDWWGLGTIVPGLVLVIFAFTDGGSAPQGWRTPYVYITLIIGVVFLAAAVYVEGWVAAQPLFPAEVFRPKGMKRLVVSLFCCYGVFGLYLFYVSYYLSTVLHTTPLQTAAWFTPMALGGIFLALMGGLVLHLIPGRILMIISGLGFLLSVLLFALIPDRVDGAPSTSFLYWAYVFPAMLCGTIGVDITYNVTNVFITTSMPARLQATAGALINSLLYLGIAFWLGVAELAVSQTKEAREGDGEDELTPREQYKIAFWLAVGLAALSLILFSTLKIGQASADMTADEKAQLAAELAERERARVRALAADEERIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIF3</accession>
    <name>A0ABR1VIF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664820.1">
        <property type="nucleotide sequence ID" value="XM_066815530.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048590"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="593"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIZ7</accession>
    <name>A0ABR1VIZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011419</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665024.1">
        <property type="nucleotide sequence ID" value="XM_066815734.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048794"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="73" mass="7823" checksum="6B907F9CDDF70B5B" modified="2025-10-08" version="1">MASNIPRMKTSCITEVTGGLHGRIIGANSAELGGAVGTANPWYPHRTIQVVVAYRHKPDYTMSSLVTTKAPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJF5</accession>
    <name>A0ABR1VJF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665191.1">
        <property type="nucleotide sequence ID" value="XM_066815901.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048961"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="466" mass="52709" checksum="ADC4EC92B8A70C1E" modified="2025-10-08" version="1">MVMGHRRGYISSSSILQQINFSYSALQLLESNTEKLRHPAPPTHTIPKPYLKIKHSKWSDEQHNVPTEFDIYDMDQAVSLLVPMALLDGRVAGCVGNLIEFTIYSAEPHDIIQRFAPPSEDYFSEYILSTRAWLEGEGALESAKPSDPDISNLAQSPVRIGSQREPPFLLGHKYVRVRLLVKADRDTLGDKISPLRRDYNKDLELMEKWDCRAGTVVVYVKTYARLAQAVAALTVIGGLIIPFTVLDRIAGVDPFNITMFTWLLSGFILVVAKSLYVRDWPWYDFLAGRVECTRLSDLADVSGVGVQLVLLFFLQRDVSSRFVTQGPYNGVFKRQLNLDRKGDSEKENEEEVRSVASLVQTGGFAIDKPIDLWTMMAAGFIVLKVLNAQGEHLICIDGRKGNFDAARPDHSAAWLTCRDFNEVALERAHDSRKMESSHKREVYMLQRVEFRWTKVLGVYVKDSTFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKR6</accession>
    <name>A0ABR1VKR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664342.1">
        <property type="nucleotide sequence ID" value="XM_066815052.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048112"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="83" mass="8845" checksum="5215DE18530E43D5" modified="2025-10-08" version="1">MNPSSDEFTTKRTKEKAARVAFADWLESELANYNLKTTASQLPPAPLALAKQKAGGAKTPASKRASKKRKLKAAAADDAGDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKU8</accession>
    <name>A0ABR1VKU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664296.1">
        <property type="nucleotide sequence ID" value="XM_066815006.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048066"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="439" mass="49351" checksum="569224F5FC0F3D29" modified="2025-10-08" version="1">MPPEYADLAPQILRQRLVVEGYPAKAIGESEIRDYLSKLSEITRMTRLLEPVTHKSDLYGWAGWIHWETSGAHFYAWEKPLLFFSVDIYTCKQFDPKLVVDFTRDYFQASDIAAKDFSSSSAPDLTLSEKAPVAPADIARYTLSDADLDKLSRKLLAEQPPKVTDALIVYRLDGTDELSNLARHIEREVFEETFGNDEGQMRQIYGLYEDVSTFFLAMDQLARRPVGALRAMRPRADLGFLTLREAEKYAGVTPAQFQAHHGLVEEADWADRTVDWGTLAVPKRHRAANRHLLAAVLFRAGQVRSCLEGARHYIMLADAELHRTFDMMGFPFAALAGTGAFSYEGSAESALLYGRPGEFFAAMEGKCAETTDKRLGPILRAFVARFVHGVGVDHRFMFEFAVGPGVRRRCRFLRGWAAVAGRSCRWYAVEDGVSLSARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VL77</accession>
    <name>A0ABR1VL77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor 5A-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664793.1">
        <property type="nucleotide sequence ID" value="XM_066815503.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048563"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04469">
        <property type="entry name" value="S1_Hex1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037318">
        <property type="entry name" value="Hex1_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor 5A-like N-terminal" evidence="2">
        <location>
            <begin position="270"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="395" mass="44574" checksum="857DBDBBC51F55D7" modified="2025-10-08" version="1">MYVPCSGTPCCREGFSRAPKAANLDFEARVPVPFSVFPSSYKETAEVETTTTTHEELEIHVPPKKAGRVGQDSSTSVSARPPPRQEEEVRITREEEQYRRPGVHRHEHEYYEEHRPSRPTSTPTYSAHDDSYDVVDHQHRPQHSPIDVIEREYRSRSHPVYKEDIRVETTVDAASCPPPSRHSHSRPVYQEEIKVESTLEPHHHHHHTPTRFQDTKVVEETVQVSQTPKPAKSTTSHHHPYSSRYSKMADQYHSEDAAPRKSGSHSGPANTVSIPCHHIRMGDILILQGRPCQVIRISTSGATGQHRYLGVDLFTKQLHEESSQYRVLDMQDGNIVAMTESGDVKPGLPVSEQGNLWGRLTQAFESGRGSVRVLVLTDAGRELAVDMKVIHGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLP3</accession>
    <name>A0ABR1VLP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664657.1">
        <property type="nucleotide sequence ID" value="XM_066815367.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048427"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="3">
        <location>
            <begin position="149"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="361"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="521" mass="57977" checksum="901254E89F69B064" modified="2025-10-08" version="1">MSEPPRRSSFGMLLRRSKSGDLGKGGRKQHQKDQQQREAIPKSPPRLPDIYNGAQPPELQSFGGDMRPDSLAIQQLRHQYPPSGRTSMDPGRPSISSAAAPPVPPIPASNNYVDPYARTESMTHRGRYSYASSAISSINSPRRVRRRKDPTPFNILIVGTRGSGKTSFLEFLKTALALPPKKRSQRATEIDEEFVAKGASSGNFIPHYVESEIDGERVGLTLWDSEGLEKNVVDLQLREMSAFMESKFEETFTEEMKVIRSPGVQDTHIHAVFLILDPARLDRNISAANSTSTMNGHGGKNGDVSRIIGGLDEDLDLQVMRILQGKTTIIPVISKADTITTAHMNVLKKTVMASLKKSNMDPLEPLGLEADDDDTPDSSRIEEGDEDEGAYDDKTSNEAESDEGEYDESLPIQGSSSSSNPKRHSTASGHQSKPSVEESDEVGIIPMSIISPDIYEPGVIGRRFPWGFADPYNEEHCDFTKLKEAVFGDWRGELRELSREQWYEGWRTSRLKQHQPSVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VMC4</accession>
    <name>A0ABR1VMC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10 11">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 10 11">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_011654</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10 11">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10 11">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 10 11"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665259.1">
        <property type="nucleotide sequence ID" value="XM_066815969.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049029"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018208">
        <property type="entry name" value="GH11_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF2">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00776">
        <property type="entry name" value="GH11_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10 11" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046109920" description="Endo-1,4-beta-xylanase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="13">
        <location>
            <begin position="24"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8071451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="23380" checksum="2FC58B8CA37667A3" modified="2025-10-08" version="1">MKITSFVAAAASLVLGVLGAPATFDHISDVMARQGYAFSSWSEGGINYRCNNGPGGSYTVDWSGPGGFVCGKGWGRGGARSVQYSGTYKPQGPGYLALYGWTRNPLIEYYVVDAHGDLSPNEVWTEKGNFTSDGGTYTIYTSTRVNQPSIVGTATFQQFWSVRTSEQRVGGTITTGNHYSEWAKHGMNLGQHDYMILATEGYTSKGKQSSGSSSITVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTL2</accession>
    <name>A0ABR1VTL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665457.1">
        <property type="nucleotide sequence ID" value="XM_066813495.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046555"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="222" mass="24347" checksum="0319A6556275F3F1" modified="2025-10-08" version="1">MSTTLPPSSYEQLPPPTPPPTRPPTPDSMTSDASSPQQAPSPPPEQQEPQSVSPPPADDPLTESLFGPPPTAATTSPPHSPNDSIHHRLRPLDHYFGPHLNHDLKQRRAVHEYMLCRMTQDQTTLYIHRAILALLLLLPPSSSSSSSSAPATSFEAEVDDRLIWELASLLQHEAALHAATARTVRTMWLLGLPRPQRGARRRLRARYRAVFHAVATESGAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUI8</accession>
    <name>A0ABR1VUI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">WD repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009545</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat WDR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665822.1">
        <property type="nucleotide sequence ID" value="XM_066813860.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046920"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051973">
        <property type="entry name" value="tRNA_Anticodon_Mtase-Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="227"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="839"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="442"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8074882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1188" mass="129079" checksum="F5F553FFCD76250B" modified="2025-10-08" version="1">MSSCDLNTVSRRHNDRHALQLRREFVLNPVTALAFFTSETDGRRYLLAGEDNHLRVYDAESSRLCGQAPIFKSQSIHGIAILPCPRGRREQRQVLFWGGTSVSVVPHASIEQLVSGDAASSWKSAEVTAPDRVLCGILSPYASGALALLTAHNELVLGQAEYGSETITFGKIASPSRPMLFSGTLSWESPDCILVASGTVFGEIVVWKHRIQTEQQPELSSEIIFIFSGHEGSIFGVSISHPIPFGDGESLTLLASCSDDRTIRIWDITEVRGDRSSQRIQHFQAFSAARETGFGDSIVPAAGEGQNVGRCLAVAMGHASRIWHVEFSFQAMPGPPSDQAVLDIWSFGEDATVQKWELSLHDLQPSVKNLGSSGPTVADPKQLTRLSHQATYHNHSGKHIWSRALTWDAAHGLLIATGGSDGRISLVRASQVASTRCLYEVPAEETSPPVTGSDIQPPTPAPAITPDVTSSNPAGQAPEGQKKKKSTVRKVKETFNHFNFVSESCLLAITNSGRLFRGIFKPEISWDEVSVVPEVRESLHSYTVIASSGIAGIALIGTSSGTVYLYRDHAIPVIEPIAKVRGKVEGLFELSRKTKYAQLSTLPTDTKSSIGLLESPSFLATAFGSPVAILLVMDGSSTDNAQVTKTELALERGFAVTTAAICNKHIILGSRNGRVSILKSDDKGYRALECRYQATTKDAITSISLLPSYKSEGAMDILTTSRDGKYRVHRITIVDEHFQGQLLHETSPPFGPVIESAWFYENIDGSKDLMLCGFRSKNFVVWNETQGREVVTADCGGAHRMFAYTPLSSSSEGCRFVFTKTSQLCVFSQSQASHSTLKSGGHGREIRAVASSGRFVATGAEDTNIRLWRYGPGSDLRCITVLEKHTTGIQTLKWHEQSYLFSSGGIEEFFVWRVTPLENDQLDVAVVCEATFTDKSEIGDLRIMDFDIQLLGEDAGANSSFAISMALSDSTLQTYSYSKDNGFRLLARGSYTGACFFQLRHLSFNDSVLEVLTAATDGRVGVWKAPIPSALNGGDVAEFTALTISRIHQSTVKSLYIREISGAGRPSYLVVTGGDDNAIAFSHLQHDSESGQLVLGKKHIVRPAHGAAITGVAILKNSLDQDQATIVSISNDQRVLKWRVVDWTTARAKIQLIESRHSAIADAGDLEQLSDGKVIVAGVGLEVWDPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV91</accession>
    <name>A0ABR1VV91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD/NAD(P)-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666077.1">
        <property type="nucleotide sequence ID" value="XM_066814115.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047175"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="113"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="403" mass="45464" checksum="6FC225F447DE1913" modified="2025-10-08" version="1">MEKPFRVIIVGGGLIGLLAAHMLAKSKIDFVVLEQRDSLFPEHGAVSVYILTPHGHPFAMVHRTDLLRCLYDTLEDGMKKYIYANKKVIDVQVFHDTCKVRCADGTTECGSIIIGADGSSSRVRHQMRTYSQLEQPLLPLGANKRPFSASFILLYGVVSVLPGMLEGTSWEAHGPGMSTSLFVGKERAWFFWYERYAFSMQEAPRKRYNKEDEARFVDKWAHVHITDSLRLQDVYEAHQSSGMTVVEEGVVQHRFGRRIVLVGDSATKVTPNLAFGFNGGVQGLVTLVNGLHGLVRRQNITRPSTAELDAVFQTYQDQALPLSRLLVDVSGESLWATIWDTWGAWVMDRYVNQATGADRRRYNKRFAPMITQSLVLDFLSEHNLPRGKMAWQNHPETAIDMCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVF2</accession>
    <name>A0ABR1VVF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="15">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_009881</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="15"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666158.1">
        <property type="nucleotide sequence ID" value="XM_066814196.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047256"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02584">
        <property type="entry name" value="RNAP_II_Rpb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02733">
        <property type="entry name" value="RNAP_II_RPB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000684">
        <property type="entry name" value="RNA_pol_II_repeat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007075">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007073">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038593">
        <property type="entry name" value="RNA_pol_Rpb1_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF37">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04992">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04990">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05001">
        <property type="entry name" value="RNA_pol_Rpb1_R"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00115">
        <property type="entry name" value="RNA_POL_II_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 15" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="17">
        <location>
            <begin position="242"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1558"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1561"/>
            <end position="1598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1607"/>
            <end position="1679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1686"/>
            <end position="1711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1718"/>
            <end position="1731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8075218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1757" mass="192809" checksum="3CC5C035C2EDEE92" modified="2025-10-08" version="1">MANLHFAHSDAPLKTVEEIQFGLLSPEEIKNMSVAHILFPETMDETRTRPRTGGLNDPRLGSVDRQFKCSTCQQNMSECPGHFGHIELAKPVFHPGFIKKIKKILESVCHNCSKVLEDRSNEEFRAAVATRDKKARFQKVWNVCKAKKLCMNELPKEEDGSFDPSGKSAAPGVGHGGCGNDQPNVRQTALQLWATSETKNEDGVKTKDKRLITPEMALNILKRISDDDLRDMGLNTDYARPEWMIITVLPVPPPPVRPSISMDGTGQGLRNEDDLTYKLGDVIRANGNVRQAIQEGSPAHIAAEFEQLLQYHVATLMDNDIAGQPQALQKSGRPVKSVRARLKGKEGRLRGNLMGKRVDFSARTVITGDANISLDEVGVPRSIARVLTYPETVTPYNIHKLHELVQRGPNEHPGAKYVIRADGTRIDLRHHRRAGAITLEYGWKVERHLQDGDFIIFNRQPSLHKESMMGHRVRVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQTEETRAEIKELCMVPLNIVSPQRNGPLMGIVQDTLAGVYKMCRRDVFITKAEVMNIMLWVPNWDGVIPEPAIYKPRPRWTGKQIASMVIPKEISLFTKPPSGDKWNPLADEGVLIQSGQLLFGLLTKKNVGAASGGIIHLAYNELGPAGAMAFLNGCQRVINYWLLHNGFSIGIGDTIPDKPTIEKVQVHIDDQKSIVAQLTAEATANTLEAAPGMSIRETFESKVSAALNAARDKAGTTTQKNLKECNNAAIMSNSGSKGSSINISQMSALVGQQIVEGKRIPFGFKYRTLPHFTKDDYSPEARGFVENSYLRGLTPSEFYFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDVSARYDGTVRNSLGDIIQFIYGEDGLDAMIVEKQTMDHWVVRDKDFESRYRLDVMEEGRITALDALTQGGQIAGDAQSQALLDMEYEAILKDRELLRRLKMQADKLDSSFQLPLNVGRIIESTMKTFNVDDSKRSDLTPEDVIPAVKDFLDRMVVVRGTDPISKEADENSTLLFKALLRARLSFKRVAIDQRLNKIAFGHVMGELESRWSRAMVNPGEMVGVLAAQSIGEPATQMTLNTFHFTGISSKNVTLGVPRLKEILNVASNIKTPSMMVFLDGDNATKERAKALRNVVEHTHLRSVTDAVEVHYDPDIQSTTIPEDEDMVESYFLIPDEAHENIDRQSRWLLRFVLDRQKMLDKNLTVDDVARRLKEEYASDLAVIWSDDNAENQVIRVRPFKNDDDKDEDGSKVVEDDVMLKRLGDHLLESLTLRGVKGIEKAFMTEGQKLAITADGALSQDKGTPGCKEWFLDTQGTALREVLAVDGVDCKRTSTNDLWQTVEVFGIEAARIALLNELRRVLAFDGSYVNERHLALLVDVMTYRGSIAAVTRHGINRADTGALMRCSFEETVEILLEAAATGELDDCRGISENVMLGQLAPMGTGHFHVFLDQSMLDTVISDNSKMGLMQGMTMKGSQDGGAATPYDTGSPLNVDYGSGAFSPPDMAMGAFSPIVEQGSASPGGFATAYGSGFGSASPYGARSPGATSPFGGTSPTSPFSSYGGSYSPTSPGAGYSPTSPLMSGNRYASSPQFSPSSPSFSPTSPGFKGTSPSSPNYSPTSPNYSPTSPSSPRHYSPTSPAHSPTSPTYSPTSPNYSPTSPNLHGGATSPSYSPVSPNYSPTSPAAYSPTSPNFSRGGAQQSPTSPQYSPTSPSILLRLLDRAVLPAPNSNGLQFSYIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW77</accession>
    <name>A0ABR1VW77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Laminaripentaose-producing beta-1 3-glucanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666431.1">
        <property type="nucleotide sequence ID" value="XM_066814469.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047529"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09220">
        <property type="entry name" value="GH64-GluB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.50">
        <property type="entry name" value="Beta-1,3-glucanase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032477">
        <property type="entry name" value="Glyco_hydro_64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037398">
        <property type="entry name" value="Glyco_hydro_64_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042517">
        <property type="entry name" value="Glyco_hydro_64_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38165">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38165:SF1">
        <property type="entry name" value="GLUCANASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16483">
        <property type="entry name" value="Glyco_hydro_64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52006">
        <property type="entry name" value="GH64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045633590" evidence="1">
        <location>
            <begin position="22"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="GH64" evidence="2">
        <location>
            <begin position="56"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS52006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="429" mass="45338" checksum="68C696E79252AEBF" modified="2025-10-08" version="1">MRGFFSLAVASATAFIGLSVATPIPITVDPGSEGDIIMTSGNTLNGTMYPSTLTNTASLQLSLQNSLGDNVNAYITGKDKNNALVILQADGSYYYPNPSGSKAPKRVSADIAIPLGSKGTTKQVTLPDFLTSGRIYFAMGTINFFTVLNDAGEIGLVQPAAENPRDPSAGVEWGFVEFTYNESGVWANLSFVDFVGPSFSMSLTLANGGTQSVRGLQPGALDKICDEMVAQAAKDGQPWDKMCVKSSAGKSLRVISPLKYRALNPDALSDYYSDYVDKVWQTYSSQDLTIDTQGAAGKVKCRVSGSTLSCAGDNRGYAKPSIDDILGCNSGPFTVQPGDNGVHTAVVPRLCAAFYRSTLLMNGGALQPSVPSTKYYSADPTIHYGRIVHKYELDGVGYTFAYDDVNPDGENAAGVLAGANPKLFSITAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWE1</accession>
    <name>A0ABR1VWE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Elongation factor G, mitochondrial</fullName>
            <shortName evidence="7">EF-Gmt</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Elongation factor G 1, mitochondrial</fullName>
            <shortName evidence="7">mEF-G 1</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Elongation factor G1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MEF1</name>
        <name evidence="9" type="ORF">PG997_010243</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666520.1">
        <property type="nucleotide sequence ID" value="XM_066814558.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047618"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04091">
        <property type="entry name" value="mtEFG1_II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047872">
        <property type="entry name" value="EFG_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636:SF2">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="79"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="88"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="163"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="217"/>
            <end position="220"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="781" mass="86315" checksum="8DA6462AEFEB4288" modified="2025-10-08" version="1">MGIASQTSSTGTPQMQWRQAPLQIQGRRYFNVSRPRLAAGGNVAAAASAALKKAAEEAASLTPEAVFAKMSPDEKKRLSKVRNIGIAAHIDSGKTTVTERVLFYTGRIKAIHEVRGKDGAGAKMDSMDLEREKGITIQSAATFCDWKKTEDGKDETYHINLIDTPGHIDFTIEVERALRVLDGAVMILCAVSGCQSQTITVDRQMKRYNVPRISFVNKMDRMGANPWKAVEQINSKLKIPAAAIQVPIGAEDQFRGVVDLIDMKAIYSEGPKGVNVRVTDEIPEEVKALAEEKRQTLIEKLADVDDEIAEIFLDEKTPTPLQIKDAIRRATIARKFTPVMMGSALADKSVQPMLDAVCDYLPMPADVENLALDRSKGEAQTKLVPYNSLPFVGLAFKLEENNYGQLTYIRVYQGTLRKGTYLFNSRNDKKVRIPRIVRMHSNEMEDVNEVGAGEICAVFGVECASGDTFTDGNLPYTMSSMFVPDAVMSLSIKPKKSTDADNFSKAMNRFQREDPTFRLHVDEESEETIISGMGELHLEIYIERLRREYKVDCITGQPRVAYRETITQRADFDYLLRRQSGGPGDYAKVGGWIEPNPDSEEANAFSNQVVGGLIPDKFISACAKGFEIACDKGPLLGHKVIGAKMAINDGATHVTDSSDYAFSLAAQMAFRKVFDEAGGVVLEPLMKTTITAPNEFQGNILMLMNKRNATIIDTEIGSEDFTLICDCSLNAMFGFSSQLRAATQGKGEFSMEFSQYAAAPPHLQKELVAKYQKELEAKRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXA7</accession>
    <name>A0ABR1VXA7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666823.1">
        <property type="nucleotide sequence ID" value="XM_066814861.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047921"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="154" mass="16830" checksum="EF4D5B84DD870399" modified="2025-10-08" version="1">MIRPTQGSRQVSQEGTELNNDDLQHTSGGLMNGKLTCQVSAEHWRGQSPFKQSTTRLGRDELIRLRMPVALRHGGANLVPEVGVANAALDKEVVKGLADALAEHKLLVNPKDMLPRGDLVVQEARVVEDGGFVGFLGWRHAVSKQVYHPALHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXU6</accession>
    <name>A0ABR1VXU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Maf-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666111.1">
        <property type="nucleotide sequence ID" value="XM_066814149.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047209"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213:SF5">
        <property type="entry name" value="BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="259" mass="28709" checksum="A2CD4682C04AB087" modified="2025-10-08" version="1">MSEKKAFAPAGPLPTRKPPPPLEIPILTYMKSHKVILASGSPRRKALLHRLGLTDFQVVPSTLPEDLCKSTLVPFEYVAATARQKALDVYERAVAKGEEPDLVISADTVIVTRDGRILEKPASEAAHIRMLQHLRDTRVHRVLSAICCLAPKEEATHPGYEIETHVEETKVYFAKEADGLLDDVIKSYVRTREGVDKAGGYAIQGLAGMVLIEKIEGSVDNVVGLPVRQMLQLCEKVVFKQGQENSEEEEEDEDDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8D3</accession>
    <name>A0ABR1W8D3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667217.1">
        <property type="nucleotide sequence ID" value="XM_066811875.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044935"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024420">
        <property type="entry name" value="TRAPP_III_complex_Trs85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975">
        <property type="entry name" value="TRANSPORT PROTEIN TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12739">
        <property type="entry name" value="TRAPPC-Trs85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="776" mass="85712" checksum="2775882A82E0A894" modified="2025-10-08" version="1">MPSSNHDSPLESIPSPPMAASAFQAQKSRYSLAEGAPRARSEITLPYRMSAPSAASLYASTLSPPGSRSQSPIGRPVSRLAAGSIFGGFANNALALVDGVGDSPGDPLNLILKAFVPHVAVYSSEDTDLLLREKGFELGLWEILRPFGDRVAGKVIIRDSNGLSRTYEDYSVHFVRYGEGIEHPEPMNSNIKSPAQSEKVAGSSEKDTGSQQTRRRGGNGADVEAVVERHLSYAEESFGISPQLLDPKQGLDTETPSPYYSLYLRRLLSGLPLVPHETFAHPVACVIAISSRNPSPIETLRRLYNDTSAGEKRLPSWVDSEYLRYYVLVHDEEKDDITKSMSLFEQMKRNLGLHCHLLRIRGTQSAATDDDSIPLATSEWMSAAEELANLRKHESQEDFEDPTRYIYESDATAIRTFIREMVTQSIIPTMERHVSVWNDQVASKRKGVTGRIMGLTRRWGFGTTSKSSSGPGSSNYDTLGFYRQDAPEAIMRKLADYCFMLRDWKLAHSTYDILRSDFHGDKAWKYHAAANEMAALSMLIMPQTMSSKTRTETIDTMFDAAFYSYLTRCTAPYGAIRCLTLGLELLRLRGGSSVDEAAKWGTRLLESRIAGPIGDALIKERLAVCYASKKAVGTHAWGARRRKSAMWSALSAETWLAQAKYIQAQRCLNEARKTYGDLPNDQGIDHFAEASAFMLEIGHQLNQHLQSNDQGENSSDDEGSEPVDEESEVMNERGRRISTLGLPGATAATLEAAPLRSQTTDEDDDVDSGKPNNDFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA67</accession>
    <name>A0ABR1WA67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008213</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667870.1">
        <property type="nucleotide sequence ID" value="XM_066812528.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045588"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF40">
        <property type="entry name" value="TETRACYCLINE-EFFLUX TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="485"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="515"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="80"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="583" mass="63327" checksum="443CD39A49AB0377" modified="2025-10-08" version="1">MTSERQPPRPTVGSHKIIMIDAETSGETSPLLGAGADGDAPGDGSENNTNPENREAWAQEFDGLPWYKRPSVYWLIGPYFLFTLAFGGVLVPRINLIVDLVCRDYMADKSLLDPTFIVTPIVLGGDNPQCQIPPVQRSVATFTLMTSVLTGALSALTAPKLGSLSDRYGRTRLLCIASIGGVLNEIVTILCAKYPESLDYHWILVGAFLDGITGSFTAGGIIGTAYTSDCSSPSKRGVYIGYLQACLFTGVALGPLIAGYLVKWTDTLLSIFYVALASHIIFMGFIFLVMPESLTKKRQLLARQKHKEEEDALAERLHSRMLVPGGAGDGRLRRNMILLAFMDTIILSVAIGSGAVTILYVEYMFHWGVFEASRYVSLMSFVRVVALLGVFPLVNYIFRVRPLQRQRRESGLHIMETNSGMDELDVWLLRIALVSDVTGIIGYCLVRTPQLFIMSGALTSFGGLGGAVIQSSITKHVPAERVGSLLGALGLLHALGRVFAPMMFNGIYAATVESFPQAFFVLLASLFGLALIGSVFIRPHLYLKEDGYAPGPTSTAEAHMYSECNDEDVVAEEDIAAGSLPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFY9</accession>
    <name>A0ABR1WFY9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008897</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668554.1">
        <property type="nucleotide sequence ID" value="XM_066813212.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046272"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8081079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="127" mass="13938" checksum="2652AD278D819625" modified="2025-10-08" version="1">MEQTEPPSPNASTAIANTFLALFILSCTRFLMGMTKMIQSAAMLREILARSLLMAECPGPGIAHRPALEDEDEHVGDRVDRHGRDHDPAQDSKAQMATLLGEDAQIKQQDGHLDLTKTEVVDGLRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL35</accession>
    <name>A0ABR1WL35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Heavy metal translocatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_005536</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668774.1">
        <property type="nucleotide sequence ID" value="XM_066809851.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042911"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF32">
        <property type="entry name" value="COPPER RESISTANCE P-TYPE ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="221"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="506"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="549"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="892"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="925"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="44"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8084265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="957" mass="103032" checksum="04BD24D362B5F8C9" modified="2025-10-08" version="1">MDQNDPAAEPLLRPSSSSTTINNSYQSISRSTTCTSRSMVTPTFQATLAIGGMSCSSCSNSITQELEKKDWISRVTVNVATSIANVEFHSKDQANQVVEAIESMGFTAQLIDRVVDSSQNPLEERARSVQIRVDGFHCGHCPLRAVRALTGTDGVLSIEDEPTESLPIIKVTYIPSAPNATIRKILATLESVDPAFKASIHHPPTAEQVSRQIHARERRQLLYRVWLTLLMAIPTLVIGIVYMSLVSAEDPSRKYLMMPWVSGINRAQLALFIMATPIFFFAADVFHRKALKEVYSLWRPGSETPILQRFYHFGSMNMLMSLGTTIAYVSSCCQLIAAAVTKPKHVDDANFYFDSVVFLTLFLLVGRVIEAYSKSKTGDAVEALGKLRPTEAILIDRSDDGNVDHVVAVDLLDFGDLVRIPHGASPPCDGKVIEGTTKFDESSLTGESRLVSKKVGDQVFSGTVNKDAPIVIQITGVAGSSMLDKIVKIVRDGQTKKAPIQEIADVLTSSFVPAITLIAILTWLTWLVLGLSGAIPESWMRESSGGWAAFSLQFAISVFVVACPCGLGLAAPTALFVGGGLAAKHGILANGGGAAFEKASKIDCVVFDKTGTLTEGGEPKVVDALLYPEEPAEEGMRGTILAALRAVEENSSHPIAKAIVSYCMRQTDQRTEVTDVEEIPGRGLKAKHSAFYLAVGNEALMNELKASITPAIVNKIHDWQNQAKSVAFIATQSDSSSPWKVVAALSIEDRIRDEAAAVIKDLRARGTNVWMLSGDNVKTARAVALRIGIPENNVIAEVLPADKAAKVTYLQSTLKAGPNEEDTTRRATVAMVGDGINDAPALTIADIGIAIGSGSDVAISSADFVLVQSDLRSVVTLLDLSKKVFQRIKLNFVWALVYNVVAIPFAAGCFYAIETRGGHVQLDPVWASLAMALSSISVVLSSLALRSRIIPGLGFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLI6</accession>
    <name>A0ABR1WLI6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668884.1">
        <property type="nucleotide sequence ID" value="XM_066809961.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043021"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="130" mass="14543" checksum="28B3087144804E37" modified="2025-10-08" version="1">MYVRFPALSNHEVVDVLVTLFRMLNPSLKPTWQNRVSGIFAETVFFHVEQDVRHAPLLLAFQIPEISRIIHELAARASESEHIHGHGAAADHANGDRRDEEGDLCDLSASVHSDWTEAVSGYKNESASRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMJ1</accession>
    <name>A0ABR1WMJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3,4-dihydroxy-2-butanone-4-phosphate synthase</fullName>
            <ecNumber evidence="2">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669228.1">
        <property type="nucleotide sequence ID" value="XM_066810305.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043365"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327:SF18">
        <property type="entry name" value="3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327">
        <property type="entry name" value="GTP CYCLOHYDROLASE II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0686">Riboflavin biosynthesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="215" mass="23286" checksum="08EE8B4DE7B86705" modified="2025-10-08" version="1">MPSAEIEKSQFDSIPDAIAAFRDGEFIVVLDDPSRENEGDLIISAQSVTTEQMAFMIRYSSGYMVTNNQDLKGTAYTLTVDGADESITTGISAHDRALTCRTLADAKATPASFRRPGHVLPLRARDGGVRVRRGHTEAAVDFCRLAGVGEVAAICEMVEDGEEVPGKAIRQAPGMMRAEGCIKFARTWGLKVCTIEDLVNHIEKTEGKYEVNGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNB0</accession>
    <name>A0ABR1WNB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669538.1">
        <property type="nucleotide sequence ID" value="XM_066810615.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043675"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011666">
        <property type="entry name" value="DUF1604"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384:SF19">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07713">
        <property type="entry name" value="DUF1604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26093">
        <property type="entry name" value="HTH_TGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="168"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="682"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="607"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="703"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="790" mass="83578" checksum="38AB46563AA7014A" modified="2025-10-08" version="1">MSTKRPRATFEADLQNQQSPYVHFGTPLPPLDRDARDDGSYVPVWKQEVRDERGRKRLHGAFTGGFSAGYFNTVGSKEGWTPSAFVSSRTNRYNKDNKDGAASDGAAAAAAKPQQQRPEDFMDEEDLADQAEAQKLQTAAGFAGLGSTEQDSAMRRGGGFADLFRSSGETMGIKLLKRMGWKEGQGIGPKIRRKARLDVGANGNGAARVDDGATETYLFAPENVRMIAFVKKLDRKGLGYAGEAKLAPMATAGTRKGPSAGSSDEEDEDGPLIRPRIGKKKAKPSRGGIGIGILNDTGSDDEDPYEIGPRISYNRVIGSDKKKKKKATTAVNPKLRSAPVLITRKDALSKAGKNLRKCHDGRLPLAGFSFGTDTDTLTSMVNSDVKYPPPKIPEGWISAKKPKGSDAANNGAAYLSTADAAKASKLDPQARAALLGEAQLPGKSVFDFLSADARQRLAAASGKTNLPPALGEIPAGYAMTPEEKQRELASQVPALEKDTAIAALTRSAAGGTGGGNTPYADDDAKRGRYRAYLEHAAGYSKAAVLPAKPPGQRPEDYLRELREFHSVARIFRPMSGMMASRFTTSSSSSSSSKFTTGSSLETSGATDLLSKPAKAKAPADPAEEAASLGMFGTMTRSTADFYPTRLLCKRFNVRPPAHVQPDGGNGEPKAEQPQQSAFETAMYGSSGVGGSSAGSRMPSSMDPTAPSSYPIPTSAAAAAGTGAGTAMTLDEHSSHSNKGEPSRDVQMTTAARPEGTKVDASVNEALEGKRAQDEVLKAIFGDDSDEDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPH0</accession>
    <name>A0ABR1WPH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT family small oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_006648</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669886.1">
        <property type="nucleotide sequence ID" value="XM_066810963.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044023"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="288"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="484"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="510"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="602"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="670"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="708"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="744"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8085377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="809" mass="90729" checksum="7BFD773EEE3CF5BF" modified="2025-10-08" version="1">MRLPFSKEEGTAASPTEIHPADHESGHSSTGNAKGDPGLHVTAAAADLEKIINDHQFDPNLPSEKLDAAKKAIEHGNVDDILAADAMFTEDSPYEEVRSAVRNTDGGEVANTARAWILGFIFVTLGSALNMFLSMRSPAISFPALVILLLVYPVGCIWAKVMPTRVFNTFGLRWTLNTGPFNIKEHVVIVLMSNVCISYAYSTDALLALQGKPFYDINLGWGFSLLFTLSSQLIGIALSGIFRRFLVWPSAMMWPNQFSNTALFYALHDKSKSDGVSTNGWYISRYRYFFIVVAGMFCYYWIPAVLFQGLSVFAFVTWIRPDNVVLNQLFGGVTGLSLIPITFDWTYTPCFHPRTRISTPCLAFFFFVILTTIGITYSGAIYADYLPMVTSQTYDNTQQTYNVSRILGSGFTFDIAKYKDYSPLFLPPAFALNYGLSFAALTAALVHIGLFHGKEIWYRFKAARNQEPDIHLRLMKKYEEAPDWWYLMLFLGSIAMGLGTVLGYNSQLPWWAFFVSIIVALVFIIPTCMILGISNIYLSLNVISPFLAGFMIPGRPIGVMMFKVFSTITLGQAQGQELTFESHQTYSGDLKLAHYMKIPPKVTFWCQVMATIWAAFVQIAVMNWTLGNIPDQPKGPFHLSERTSLLLLVHCVGVIGPQRMFGPGSIYAKFNWFWLIGAGLPVLLWVLIRKLRVPHAHHFNAPIMLGAMSWLPPATPLSFSTWAIFGLIFNYWIKKRWNGWWRTYNYLTAAGLDAGLVISTAVIFFAITLPNVKIPQWWGNVDIYNTVDASYTGWLKTVSEGETFGPATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPX2</accession>
    <name>A0ABR1WPX2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FAD-dependent monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006855</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670093.1">
        <property type="nucleotide sequence ID" value="XM_066811170.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044230"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="10"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="477" mass="52801" checksum="5C16A3BF9EB6581B" modified="2025-10-08" version="1">MDGLGTGGRFKVIIVGAGVAGLTLAHAFDKAAGIDYVVLDKHPVAPAWGSSISMYPNGCRILDQLGLYDVLLAKTAETQAFHLRGSDGKTYTTSPFLKEISDRNGYVAMTFERKDFLQTLYDNLPDKSKVIEHARVARIIEEASRVKVVLADGAVHEGDIVIGCDGIHSAVRELMWERAHRLCPGLITVGEKQSITATYTCLTGVAPYQYGLGADAVSAVSHDGFSFLFLTQPDHIYFFLFIKKLPGGQKVSKYPTRLRFTEADADSEAARFLDCPISETLVFGDVWKTRTRGVLRAQGHAQRGFGGNLAMESAVVLANEIYAAVDRRRHRSDDEKEEKKPGDDEIRRAFQSYQESHMPRIKLFYYLSWAWTRMQAYDGWGCVLFVPGAKQVAVLMASAPKLRFVPFDEGAGTLSWAKQKWELPAEKKDNNEPRIGSSGRTVFSKGLVFLFVISAFMFYSAGVWSLGRGVRSPLDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ45</accession>
    <name>A0ABR1WQ45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670168.1">
        <property type="nucleotide sequence ID" value="XM_066811245.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044305"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="178" mass="19119" checksum="1272AA77BAB42978" modified="2025-10-08" version="1">MAAWQPLAPDDVEAVLRIADVIHSELPEGAHVFAERIRLFPEGCLALVKQGNGNGDRELCGYTISHPIRRRQPPALDAVLGAIPPDASQYYIHDLCVLPEFRGQGLAGQGIRRLLSVAAANPGRFPDGACLVSVYGTVSFWARYGFSPPEPAIDAALAEKVRGYGEDARYLEGPAASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ65</accession>
    <name>A0ABR1WQ65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta-Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670188.1">
        <property type="nucleotide sequence ID" value="XM_066811265.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044325"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="152"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="386" mass="42289" checksum="BDE8D216DAD3BAD8" modified="2025-10-08" version="1">MSSSTTIWSSQPFRTLYTVGFWSVNIPHLLYLALRNSIAPIRAVPQWGYQTSMGAAILRALFRYLAVIRYQQPRQMVPGKAQDRFVLIAPPDATLFRGVLGAPATATQPEPVGAVWSPAPVPVAVAAALPGNNDDKITTGNPPPPPRHRLCRGGGFVTGWDPDENSKNISALATDHFDGTAHVLYAQYRLASRAHPFPAAVQDLLAAYHHVLGLGVPPRDVVLMGDSAGANLVLAVLRYLAAQGLRQPGGAVLFSPWVEVTAEAVQRYSRSVASRHDILDVPLLEWGVDAYRPQGKPLTQEEEGYISPLHHPFRLETRLYVNAGSLDGVYESISLFARQMADVAGNRVRFHTTENMPHDYFLTYPLLGTKEEACAALRNARDFLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQQ7</accession>
    <name>A0ABR1WQQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005619</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668857.1">
        <property type="nucleotide sequence ID" value="XM_066809934.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042994"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539449" description="Extracellular membrane protein CFEM domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="28628" checksum="332DD684A9FAAC73" modified="2025-10-08" version="1">MRSSLPATVLALLPSLVSATIAQSACLHIKSVDLAQKAKCRGLDQSLLRGCFESVPQLDSATIVEQCLVDAGCTADESKRETHSLIAWCDAHFGSDLDLKRRGIDPLPRPTPLTQAPDVYIRAAATTGAPAADASPSPCSTETEVEISSCKPDDMYDCTKTMTKSMVCAQGNMCMTDNSGNNICMFRKDSMTTSGAVVGIFLAVVLALTVGSLFFLCCKDKRDQKRARAKSEAAAIAKANAVSSGPSMRDTTRSASQRTAGGHGDGPNPFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQT6</accession>
    <name>A0ABR1WQT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006057</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669295.1">
        <property type="nucleotide sequence ID" value="XM_066810372.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043432"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="52143" checksum="A0AB388A94CDB4A0" modified="2025-10-08" version="1">MDELRQTFGQVRMPKSLLLGLAVPFAVLLWAVGKAVYNVYFHPLASYPGPFLARATRLYHAYYDIKGVSIWKVKDWHEKYGPVVRIAPDELSYTDSRAWPAIYGFPTRDGTGNFEKDPQWWNKAPSGILSIVDADEAGHRLMRRLQNPAFSEKALRSQERVIRGYIDLLIQKLHGLASDPDAAADVDMVSWYSFTTFDIIGDLAFGEPFHCLRDAVWHWWLDAVFDLFQDGVFMRAARRFSWPFPRLLAWLFVPKKLVKNRMDQFMFTVERVNRRLQLNTDRPDFRRFALLPGDDQFLSYILNAEGEKAMSMEETYVCTQVLIVAGSETTATALTGATYLLLENPETLARLTAEIKSRFKTEDEITIQSTAELPYLNAVVQESLRLCPPGPAVFPRVVPPGGRGRLRPLAADRSSQNFVDPESFIPDRWLGDPRFEKDDKAACQPFSYGPRNCIGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WR21</accession>
    <name>A0ABR1WR21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peptidase S59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_006191</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin GLFG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669429.1">
        <property type="nucleotide sequence ID" value="XM_066810506.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043566"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1610.10">
        <property type="entry name" value="Peptidase S59, nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037665">
        <property type="entry name" value="Nucleoporin_S59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007230">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036903">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021967">
        <property type="entry name" value="Nup98_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198">
        <property type="entry name" value="NUCLEOPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04096">
        <property type="entry name" value="Nucleoporin2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12110">
        <property type="entry name" value="Nup96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82215">
        <property type="entry name" value="C-terminal autoproteolytic domain of nucleoporin nup98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51434">
        <property type="entry name" value="NUP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="5" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="8" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase S59" evidence="11">
        <location>
            <begin position="892"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="428"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="527"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="648"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="704"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="790"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="817"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1041"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1189"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1262"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="440"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="546"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="581"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="597"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="624"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="650"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="667"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="704"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="726"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="827"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="850"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1198"/>
            <end position="1208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8084920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1905" mass="199413" checksum="B67E0EEAFD816A57" modified="2025-10-08" version="1">MSFGSGGFGGFGSNNNTTNTSTGFGGFGSNNATSGGFGANTNTNTGGGFGSANTGGGLFGGGGNTSNTGGFGSTAGGFGSANTTSAFGGAAKPAFGASPSGGLFGSTANTTANSGGFGGGGFGSNNTAASTSTKPAFGAGATTGTTGGLFGGGSAAAPSTGFGGGSFGAPASTALGGNLGEAPGTAATAFQPLVEKENATGSAQNSFQNILFQDPYKKWSAEELRLQDYNSQRRYGSGGGGGFGSGGNTFGSTGFGSNSATTSGFGSNNTATTGGGLFGSANNNATSTGFGAQNTANTGFGSAGGSGLFGAAKPATGGLFGSTPSAAPAASTGGGLFGGGGTGFGANTTNTSGGFGAANNTAGGGLFGGGNNAAQAKPSGFSFGNTANNTNTTSTGFGANNNTTSAFGSNTGGTGAFGNTQANTGGGGLFGNAANTQQNTGGGFGSNTGGFGQQNNQQQGGGLFGNQQKPATGGGVFGSAATPSTNTGGGLFGNANTNTNTGFGASAQAPSGGGLFGGAKPATGGGLFGNAAPAQNNTQGGGLFGGLNNQNQQQTQQPQTGGGLFGGLNQSQPKPGGLFGASTQPAGGSVFGNAQNQQQSGLFGSSQGQQQPQGGLGSSLFGGASTQSQNQPQALTASVNDPTAFGATSLFGNLPTQSNDPGPLATPLSSKSQTRRPSVLPIYKLNPAAGSRFNTPQKRGFGFSYSTYGTPTSPSSASSTPGTGSQSLLTGSLTRSMGKSISTSNLRRSYNVDDSLLAPGAFSASTSSRMFGNNNVKKLVINRELRTDLFSTPTKDKSPQDTPNGSRKLAKRVSFDTSNGEAAENGDAQNGTAEQSSNNGYIRPNGVNGARSSPLSSEMEQITGKELAIVHEEEPAASSAPASTDTLSDREPGEYWMKPSKEEIDNMNRVQRQKVVDLTVGRVNCGWVKFKVPVDLNTVDYGNLFENIVVFVVRSCTVYPNQAKKPAVGKGLNVPSLINLESSYPRASMTSKGRKGPSLAKHVDRLKRIPGTKFENYNTETGEWTFSVEHFTTYGLDYDDEEGVETDPSAEMSGVEHQRAQPEPEFSAAEYDEEDSFELRRRERALPGAFDGDIAVDDEEVPEMAEADEEYAMSEDQDAGASLRHHLAAEQKDDSLSVSDSHLDFVQETPAGIMRARMRAIKESATPVKVQVAAGDDWMDMLQKTISPRKRDRVHLKSQREADNYGKESVLDVKSPSKKRVVSDSKGFATSIDLMKSIFDQAKAPAEVVQPLVRPQNAKWPYKRTPKTLDTSDMDDKERQWHSVPRPNWGPSGTLVFAGTPEDTPFGRSGRVIEKNGLMTVMKGAIVSSSQDIRIAKFTNEMSAKALQAHADLTEIYLDGGVPTVMGPRVSIREFATETGSKNAAAEHEKLVWELASVLFDSIKVPSDLQNDPDAAEKIRRENLSKFWEQMLDEETNKGISMARTSEEKALASLAGHRIAEACKHLLDGKDFRLATLVALIGSSDAMKKDMREQIKEWKDAHVLPELSQPLRALYEMLSGNVCACEGGKNASTENRMKSFVISKEFGLNWKQAFGLRLWYAISGDDFVADAVEKYQGDVSQEKEIPPMTWFAEEGIRSIWNDQEEGQRQDLIWGLLQLYSNDRADLEAILRPENSQLSPLDYRLCWQLGQALTATGKVSFGKNADEKTDAATTSFASQLTTEGSWEEAAFILLHLTDPNARTKAIQEHLCRHAGLIGNEQSESFKKLTEKLKIPTRWIWHAKALFMRSVKKDASSEVQCLLRADSYAEAHRTFIKDVAPVAIIERDFHALADLLRQFDGRQSQVPDWNLGGEIYKAFLQLVDYQSRHEQPPNALVNGLLEGLPAMHGNTPEAGIQEYAALTDMAAVVASVVGDMAKLGQVSPQLKHTINKQQLTDANYRWIINAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRB8</accession>
    <name>A0ABR1WRB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669158.1">
        <property type="nucleotide sequence ID" value="XM_066810235.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043295"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="109" mass="11884" checksum="B820108B43913924" modified="2025-10-08" version="1">MIPPSFGTCPRAVQLRLLYALSELRIALYDVRKAYTSAGIRTVGCKTCNFFLGLGLRGHGTSAAQDANDHANPDRKDGPLERGFKPNLPQQPGHPAWIYKATETASTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRD4</accession>
    <name>A0ABR1WRD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxisomal membrane protein PMP27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006282</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669520.1">
        <property type="nucleotide sequence ID" value="XM_066810597.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043657"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF50">
        <property type="entry name" value="PEROXIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="235" mass="26185" checksum="C7F7DC50E057627F" modified="2025-10-08" version="1">MVADALIYHPSVSHYLKFVATTAGRDKVLRTLQYFSRFYAWYLLRTNGTKGEIAPFDAIKKQFGLARKLMRVGKNVEHFKAAATAADAKATMDPVLRYAAVGRQLGYAGYLTFDAATVLDSLGVRKWQGAPRAQREAYRFWAMGLMCSVVAQFYTLYRLREREAKVDKKEGEGVVEAKRIAIERNTSQLQLLSDLCDLAIPTSALAWTSFDDGFVGLAGTVSSLIGAYTQWKKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWP4</accession>
    <name>A0ABR1WWP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002538</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670471.1">
        <property type="nucleotide sequence ID" value="XM_066806853.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039913"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF45">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="163"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8087577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="35654" checksum="9088F34A2EAC1A6A" modified="2025-10-08" version="1">MSSYLPSFSQPQSRRNSFAASRANSYVRSRPGSAQGSRANTVVASRRNSASRPPSAHAGAASGTEKDEETDTDLAEQNIPALYIPQNEKGEPMAGRIVGGKHDTPECEQIDADFGLIKRVDIDMPLTLTEIVNENGKEYIVLNFATGDKQNPFNWNPWYKRSISTILNLMTLFIGLATTAYSSGIGSMCKEFGVSEFMGQLGLFTFNIACAIAPMVLAPFCELTGRKVVYAGAFLCFSLLFIGLALAKNIATIIGLRLLLGLFGCVGTILVGGTFDDMYEPRHRGRPMAMFSFVAIFGTVSAPIYAGFIDQAIGWRWIEGVQGIANIPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX46</accession>
    <name>A0ABR1WX46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_002682</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Plastid</location>
            <location evidence="14">Chloroplast outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670615.1">
        <property type="nucleotide sequence ID" value="XM_066806997.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040057"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045058">
        <property type="entry name" value="GIMA/IAN/Toc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903">
        <property type="entry name" value="GTPASE, IMAP FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903:SF135">
        <property type="entry name" value="TRANSLOCASE OF CHLOROPLAST 120, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1002">Plastid outer membrane</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="G" evidence="16">
        <location>
            <begin position="2"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="203"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8087721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="283" mass="32449" checksum="315877731A9670E6" modified="2025-10-08" version="1">MTGAGKTTFISKVTGRTDLEIGHSLTSCTRDIQVIETKIDGQTVSFVDTPGFSDTHMSDTEVLQLIADYLAAAYKRDMKLSGIIYLHPISDTRVTHHATKNLQMFQKLTGEKNLKNVVLTTSMWDKVTPEEGTAREKELKDKFWRVLLAFEAKAVRYAGTTESAQRLVSQMLADNKPFYLQLQEEMGKDNKALRDTAAGREVMVELERLKKEHRREVKEMEDLLRNSAEENRNVVEALKEHYHGRLVELEKTLRDERTMNEEAVRSLRERIEDLESRGRCAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXQ6</accession>
    <name>A0ABR1WXQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002889</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670822.1">
        <property type="nucleotide sequence ID" value="XM_066807204.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040264"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="392" mass="44290" checksum="37138067976417F7" modified="2025-10-08" version="1">MSFSGMLSRLQGQPDSYDKKAKYRFGKTLGAGTYGIVREADGPTGKVAIKIILKKNVKGNEKMVYDELDMLQRLKHPSIVRFVDWFESRDKYYIVTELATGGELFDRICEQGKFTEKDASQTIKQVLGAVDYLHRNNVVHRDLKPENLLYLSKDPNSDLVLADFGIAKMLDTKDEVLTTMAGSFGYAAPEVMLKKGHGKPVDMWSMGVITYTLLCGYSPFRSENLQDLIDECSNAQVVFHERYWKDVSQDAKDFIMHLLQPEADNRWTSQQALDHIWLSGKNATDHNLLPEIKAYMAKARLKRGIEMVKLANRIEALKMQEDDPENPDLPQNPATAASAAAASGKDKLNKAVKGAIFREVVMAKVREMKEQEQTLKVKEEVEKEARRKSFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXW5</accession>
    <name>A0ABR1WXW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670826.1">
        <property type="nucleotide sequence ID" value="XM_066807208.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040268"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="510"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="544" mass="60862" checksum="3C7E08E660689E4A" modified="2025-10-08" version="1">MVDKDSSAGDGDGEGEVPYGNGDYNLPDFIGEPNAPQRLELQRLADQQEIEQERLASQQARALASSRPEERQRLVAQQQDERRRLRDRHLGEQQRLIGHQQRRSPHHPRLQIPWSSLYTDIYEPPPPSAGLRTNAGVGQRWKAPFVESPLRNTTNADAVAYSTTSAADALTPPSEEEPEGDVQEAERDKEQIVKSKAKREEEKKREREAEILHVEGELPGFGSFTTPRPEDSIVEAYFLPQDLQFAPASKEARRACPSRWNPSMPRAPFESVVRPAPTSAEWNQTPVTYFNDGTPHPRPGDILPLPPPRRNEAAGAYLRRPRLNEERQTGNPQGDDGNMNAGGFIRHQPTSHEGDYRNDSAPYYSHPAAESNYYNNGTFHHPQPMRMHNTPYGPQERPFNAANNDDRHMSDYSNHNPYPTPYSRTGYNAPPRHRNEDGLEMLSNVAAAQPPASSLPPLPQHRPQHGYYHPDPRYSSADRTTPPPSSPISAPTSGRSNIALPQLPYLGQGPAPASAPTAPSSSRSPCRRRPLAQQHDNDDTEMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY46</accession>
    <name>A0ABR1WY46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterogeneous nuclear ribonucleoprotein HRP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670979.1">
        <property type="nucleotide sequence ID" value="XM_066807361.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040421"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="117" mass="13009" checksum="68E19311941F0AD8" modified="2025-10-08" version="1">MTEPENMEDDLFADLYDDNEPSSAPAPAKQEQPVEPPPPAPAQPEAHVEDEPAYDPNQNGYNDDYQQQGEYEDDDDDVDFNLGNNPPRDVDTSTPMRDEVSTPNYHSTRGPSAKEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYD6</accession>
    <name>A0ABR1WYD6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U3 small nucleolar RNA-associated protein 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003137</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671070.1">
        <property type="nucleotide sequence ID" value="XM_066807452.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040512"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052575">
        <property type="entry name" value="SSU_processome_comp_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046523">
        <property type="entry name" value="UTP20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011430">
        <property type="entry name" value="UTP20_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695:SF11">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20416">
        <property type="entry name" value="UTP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07539">
        <property type="entry name" value="UTP20_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20 N-terminal" evidence="3">
        <location>
            <begin position="920"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20" evidence="4">
        <location>
            <begin position="1767"/>
            <end position="1984"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="1">
        <location>
            <begin position="2243"/>
            <end position="2281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="640"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1145"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2496"/>
            <end position="2530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2671"/>
            <end position="2700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1160"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2503"/>
            <end position="2527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="2671"/>
            <end position="2686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2700" mass="303444" checksum="F7302823FCDEC7BD" modified="2025-10-08" version="1">MTPTLSGRIIKTRKGKSGTLHQKNHRWESFTTKIAKLHSLDPLRKVRRHDLDAEDLDVTTSYLRNGLEKWSDLDISKGFTSFKREVRLFCESLPQILHYEDKIMDLLEKYISLQEKESLESLLDLMTAFAHDLGTRFEKHYARALVLIANIAGSRQDADVIEWTFASLAFLFKYLSRLLVADLRPTFDVIAPLLGKARNPPHIARFAAEAMSFLIKKAASPSHREKSLPIIIEHARKDLASVRGDRQYGLFYHGLMTMFAEAIKGQGNNVHTTGPTTFQALLASVPAEDLVSTDDTMPTWAGLVCGITVSIIHHTTADTFGSIADAVYEQKTKDATDNKTPLQNILYIRVLGTVAGVRRGNRISDWSALLDCLQTSLQGLCSDASSLDGIDHIAIWRFILVNTAIIWNASTMDAIIPHMAHIVKVLTREPLMKWFIPFCSYLSDLDASRFRSLFLKEFQKFVVSHWSEDSNEDMLCVLIPRMVNQRALPSPREPETFTLPQSWQSHIVRKFERLEISTFPEEGASSAYDKDPKTWRDKCLPKYSALLQLLECSTIHPSTISPIREVLLRKLKLALRPSQSPPTDEARFIVSQGFHAYLRMSKAVAAPFEKSLRPLLRAAAPRYCTLAGFLEAMHTYEDQVHDSDGQDSQSGGSATPEKEDDPLLRSLVNNLSLDSPSLRTASLRLLVKLDIAPDQLDALANMLQVQQMPLDLENIRAISVHLRKLGGIYSQLDQGSWLRQAIPSFLFGMMTVKVSPVWESVLEALQQVSQTASGEEAICDRAFKWVKGRTALQDELAGDVGKDEATPPFKKGLTDFECLNLDRLLRNAKTQDRVIVNPSDILLETFEENQQFVPMVEENQQLVPIVPKTSRSQALKVMSAVPSLIEKRSKIIVPIFLPWSSPEEDREAMEIDSDQSAGKSWSLADRKALLAVFSQFINPRVLFQQQKVYESLLHLLANGDIDIQKSALKAILAWKQEGVKPYQETLEYLLDEARFKNELTVLFQGDNKVQPEHRAEVMPVLLRLLYGRTISKKGVASGRGGLQAIRLAVLRNLTVEDTGDFLQIALGDLRGKVVLDNTGVREDILSQDPTSMHKQVNARKQVGFLNMATIIINELGVSVEKYTDTLLNAVLYCLITACRKLGHTAEKTGEDQPDNQTSEEAAEDEAEDELSDNDASLVRDVRTISLKCVISLLRNAPAFNWDPYKDILIKEVVSPRLDNFAVENTQGISGTFQFLSTLSMMPKTALFLGVDERIIPKLMDCLANKKAKDEVRVFTLSIVRNLVKLSQAPAAESEFNEIIKEDLIDRNLELILGQIGGVLRTNQATGKDLDNDAEIQIGKDLLVACIDTIVELSPIVQQSEQAPGLIEISVFLLNQPSRRVNPKVKGNILTILQTFLQLEGLRSNEELRQRIYTTISSLFGFFKDRPNRLSLSKVLAVFAEEDTTIVEVAALCSDLNSFKEGRIDEPDYNTRLAAFNSLSKPRQPPFNPRQWQPLLHNLIFYIKHDEEYGILSMNSADALCRFTDTVKASTGTDRAIYEGMLSDIVLPAIYSGARESSETVRREVTRVLGYLVSHLPSWTPVSDLVGLDPPPNEQDSDPSFFSHILSPATSRQMRALQLLSKVNFHSELSSRNLAHFFVPLLEHFIFDREDGTDDHGVGAQATTTISDLAISLEWPQFRAILKRYSGYIESKPESQKQLVRLLGKIVDSLFIAASERDSDAMDVDDGSTQGQQTKRHRLAKTMPAPEKFNEDITSNILPSLLDYIREKDETTVSSRVPVGIIIVKLLKLLPTEILEQKLPGVLSDISQILRSKAWDAREMARDTLAKMSSLLGASCFGFILDELRGALTKGYQLHVLSYTMHTIFVHVIPQFQPGDLDYCLDKIVTIIMDDIFGITGQEKDAEEYTSKTKEVKSSKSQDSMELIARTASIDHLVELIRPLQALLLEKLDLKMVRKIDELLTRIANGLLSNAAAESRETLVFCYEVVQGVYNSRKPKAEVKLDYKLRRYLVQKGAKKSGERGETSKHTYKLVRFSLDVLRSVFRKHDSLRNAGNITGFIPIIGDAVVEGEEEVKIAAYKLLQVIVKVPFKTDELTKLYKISAKDAVKSMGMSTSTTSDLAQTALKLISVILRDRRDTKINDAGIDMLLGKLKDDLTEPLYRHVTFNFLRSVLDRKIETASVPGAFFQFLRDYPQKKNRWAKQIKFIVANLEYEREGGRLSVMEIIHLLLMKSADDFVQEVATNCFIPLVLRLANDDSEKCRLAAGELIKEIFRKADKERTSKFLALPRGWLEQDGDQKKLSVFGLAIQSFCLYFDAKEPTSRDESDLMLVIKSMIEVLDDFSGGSDWELVNTVVQNVPILMQKFPSQVLSHEELWHAIAKPLTSEHPTLKLSSIKLLNLYLDDFYKQDSSDTKKDALVGSHGLQLDKSTVEALTVLAVGLLDPGTISRWKKRMAKKANSAFEDDAMSTNQQPTPIDEALASEVVLTLVRLAKFLDPKPAVSDQSSDADNEEQDASDSDSEEEWGGLDEPEQPKTKITLHTLFNFLSDILIAETPPRTAALVPKVAAMDLLHLFVSTLEPATVQPSLNMLLTPLHHLTDPNITVPSSVEDTFQPRYDALRVKAEESMDVLQKKMGTEAYTTELYAVREAARRRREGRARKRKIEAVAAPERYGKWKKGRLDKKVKRRKEKKGDQRARRQGGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYE2</accession>
    <name>A0ABR1WYE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671061.1">
        <property type="nucleotide sequence ID" value="XM_066807443.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040503"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="19220" checksum="B3BF3549858B373A" modified="2025-10-08" version="1">MLHAPINTSEEKAELHTSSPNSSGQRHIGTAFLRAASKGKPGETWAKSQLAGLGALGVLGGQIDLQFHFQPSAAAQSSASNSTDLASTVAQLPHCVCGPKRQDFLKGIGFCIAISSGCSSEDVNKLQDLAPKICQSVSDNPSPSEVAKASAAVTSAVGAAPTESDKSAAMRPEVGFGFMGAAALAALAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYI0</accession>
    <name>A0ABR1WYI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671115.1">
        <property type="nucleotide sequence ID" value="XM_066807497.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040557"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="370" mass="40030" checksum="78B83D34242E5526" modified="2025-10-08" version="1">MAHKFSVLQDMLFDNASDGMEATSELAEDSIESRLGDIISAIKRLAQHAINTNDGSPSQQSLNPLNATLAFSQSNAITESFDRAMRAIRSETYRAAGQVDDALRVSQDSHMSGPVEGSIALPGIDRGHELNKLLSLEFDEGKSFYRLADTNLNMPSIIVDQEDDLAPISISPGTILLLPTSRNVKILQHAYGRALKHKVDLIQSYSTAAGTGSAMAAPKRHKPAHENDSMTALPKKYKFGPFIDMKTAEISGIMKEKSGTSELVLAFLLPSGDCQYVEVTSGNTNEKAAVKDNDVVVPVSDDAIKLLYELYGELKELIARRMATAGAQGPAQAQPAHDPTDVALFRRMRDATLGDEDDNGPGSKRVKTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X077</accession>
    <name>A0ABR1X077_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FMN-dependent dehydrogenase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003779</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671712.1">
        <property type="nucleotide sequence ID" value="XM_066808094.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041154"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02922">
        <property type="entry name" value="FCB2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037458">
        <property type="entry name" value="L-MDH/L-LDH_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF82">
        <property type="entry name" value="CYTOCHROME B2, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G07200)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="7">
        <location>
            <begin position="33"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="8">
        <location>
            <begin position="124"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="528" mass="57124" checksum="BFFEB6244526644B" modified="2025-10-08" version="1">MKTFSAEEGKSRGFLTGAGGEDLHDGLSNRILVAKHTSPDSCWVVLYGHVYDVTDFLASHPGGSKVILQLAGRDATEEYDPIHPPGTLEENLKPEAKLGKIDPQTLVNPTKPAAKEEKKDEAEPPLESLLNLNEIEELAAKKMSKRAWAYYYSSSDDTWSKSNNNHVYRNILLRPRVFVDCTLCDSSTTLLGTKVGLPLFVAPAAMARLGHPDGEQGIARAASKFGALQIISNNASMTPEQIVSDAKPGQMFGWQLYVQNDRAKSEAMLARINKMSDKFKLICLTLDAPVPGKRELDEKSSFVNTAPVAAAAKTGGEASRPGGGGVGQQLFWGTAADLTWKITLPWLAKHTDLPIVLKGIQTHEDAYLAAQYAPQVKAIILSNHGGRALDTAPPAIHTLLEIRKYCPEVLSKIEVWVDGGIKRGTDIVKALCLGAKAVGIGRAALFGLGAGGQAGVERVFESKSRKAVSFRPRLCIFVLSTDSYATMTVLKAETETCMRLLGAKDISALGPRHVSAPLPAPNLKFYWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0L3</accession>
    <name>A0ABR1X0L3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SPX-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003935</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671868.1">
        <property type="nucleotide sequence ID" value="XM_066808250.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041310"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07751">
        <property type="entry name" value="PolyPPase_VTC4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14480">
        <property type="entry name" value="SPX_VTC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="730"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="757"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="799"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="34"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="63"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="549"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="569"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="826" mass="94664" checksum="043D16D4F9EC74AF" modified="2025-10-08" version="1">MLIIEDLQTQKKSWISTRHGLHPSWRAKPGLIVMKFGEQLRTSVISEYQWYYVDYDDLKEQLKKASGPPVGDDSASGPSQPSKNKNKQKAPEQEWTENDEARFLQRLDEELEKVYNKTQVKTSEIQRRIMWEEKEVDSLVKRMHDRGPNEQGPAEEEFVAREEFISDIIADVHDLAKFVQINYTAFYKIIKKHDKMTGWYLKPVWETRLKSKPFYREDYDRDVVKLSKMYDNVRTRGNPVKGDSSAGGSQASFVRQTTKYWVHPDNVTELKLIILKHLPVLVFNAKKEFEQADSAITSIYYDNPEKWDLYEGRLKKTEGAEAIRLRWYGGMQNDQIFVERKTHREDWTGEQSVKARFNVKEKNVNSYMRGDLLPAALFEKARKEGKKQEKQIAEEERLAQEVQYSVLKKGYKPVCRSFYNRTAFQLPADARVRISLDTELSMVREDNLDGVARAGKNWRRTDIGIDWPFSQLPAKDIVRFPYAVLEVKLQTQHGQEPPEWVRELIASHLVEAVPKFSKFIHGCASLFPDRIKLLPYWMPQMDVDIRKPASKDFGIRRPNHSSASGSTSDADDDDDYDSDDEEAGHNGARGDHTNGESSTRDQAVAAAVADLEDQTAGHATADADYPLYDSEDEESDLDDALEESRRVGGWTYYSALGKKYARAAGQGTWTVLKTIVPHPQGTTVPVSNRQQMFFGDQVVSTKKVKAPKGKRIYVPVRVEPKVYFAAERTFLGWLEFSIYIGTIAVTLLNFGTKPSLVSFIVAGVFTLLAILALCYSVAIYLYRSGAIRERKAAKFYDKWGPSVLCVSLFIAVGLNFLFEGREREMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X139</accession>
    <name>A0ABR1X139_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671997.1">
        <property type="nucleotide sequence ID" value="XM_066808379.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041439"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="618" mass="67375" checksum="929589DEEEE884D7" modified="2025-10-08" version="1">MRRSALQARNLSLSPCCPYNAARRLSRGGFRLPASERDPRTPEPSAPMEEMPPSPPRPRLRLKRRNITTQLNAPTQQFLASVAAADVPIPSVEEPSFVNTDEDMVDGLSEVDMIEQDNMGLFEQLRARAFSPPKTPAGDAAPASSASEYPDWSIESCWSGSDAESSPDFSHASDDDDCHCPNANGPECDDSDSPLPITPAARSRKPRRAPWTKAMSAHLWSTYMLYLQDPRVTPFRLGKSRIPPEGVCNRVAREAKRSWKGSNAVTPANRDSTPTAESSKPFIQWPHTCAATKAQLRELCRLKASSQPGKAMYTSRSPTPFQVAAHRRWNRRHGPARSPSAFSAQDMAMSLTLSTSETMQPHAPLAQLTCSQPEPEDMSTPIAASSAAAPEHALEDVPSASRPRLASPFFARSYGPSSSNPLVGGEDVRRQPHTVGARKLLKSPVRLTRSKSGTQKRRSVKSLEDQPRRRPSLSAALWGFPPTEPESQAGNKTLFSSTASTENDSMFIPRSTAMPDPFAPAETGSSAGLSVAAAAPQVPRLGSPFGASHTFPNRLSQPLGFNLTALRRGFATVQQPSETNPPSTPSRSSLASRLAYIDQRLKDFRSRNNVPRRSQSPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1X5</accession>
    <name>A0ABR1X1X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glycine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672223.1">
        <property type="nucleotide sequence ID" value="XM_066808605.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041665"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00858">
        <property type="entry name" value="GlyRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="198"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="660" mass="73787" checksum="3CCCD4FBCB90DD4A" modified="2025-10-08" version="1">MTTSATTLKGQPLDRPALDSMLRRRMFYTPSFEIYGGVAGLYDYGPPGCGLQANVVDAWRKHFVLEEDMLEIDCSVLKTSGHVDKFADWMCKDPKNGEILRADHFVEEILESRLKGDKEARGQKVEEKEEDPKKKKRKNKGAVEAVKLDDAVVQEYEETLAKIDNYNGAELGELINKHDLKNPATGVQPSPPVAFNLMFQTSIGPSSNLPGYLRPETAQGQFLNFSKLLEFNQAKMPFASASVGRSYRNEISPRAGLLRVREFLMAEIEHFVDPQGGKKHPRFDEVKDVELVLLNRETQLSGKTNVEKVAIGEAVAKGTVDNETLGYFLARIHLFLKKIGVDQSKIRFRQHMANEMAHYAADCWDAELFTSYGWIECVGCADRSAYDLSVHAKKTGAPLIVRERLPAPVKVEEWVVDVDKKKFGPHFKKDGKTVEAALMETSQAQREEFAKALGASGSLTLDVPGVGDGKVAVPKELVVIEKRTRTENTREFTPNVIEPSFGIGRILYALMEHCYWSRGSEGGDEARGVLSFPPTVAPTKVLIVPLSSNEQFTPFCYKLSQKLRKRGISSRIDDSSATIGKRYSRNDELGTPLGITIDFQTVKDQTVTLRDRDSTKQVRADEDRIIQAIQSMVDGSKSWQDIESELPAFEGQEVEVTIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1Z4</accession>
    <name>A0ABR1X1Z4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004372</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672305.1">
        <property type="nucleotide sequence ID" value="XM_066808687.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041747"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16620">
        <property type="entry name" value="vRING-HC-C4C4_RBBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032922">
        <property type="entry name" value="SON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46528">
        <property type="entry name" value="PROTEIN SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46528:SF1">
        <property type="entry name" value="PROTEIN SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="26"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="541"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="568"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="645"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="686"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="702"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="789"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="822"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="840"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="873"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="901"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="916" mass="101782" checksum="ADF458BF56A10003" modified="2025-10-08" version="1">MASLTPVQIELANSLTQDELPTKLRCAICSKLAVNAFRLPCCETAICESCQSTLPSSCPVCEHSPVSGTDCTIYKSLRTTIRVFLKTEEKKREASRPKTNTPTPAPPSDPAPASVNAEPFPEAPPADTTAAIPIREQSVVHQNETSRHTSGQDVADVSTLPEQESSLDHDQEVAVKEDVTDKDNDDGQAPEDGPHDQTDFEGQPTEETEEAIEASHEDAEPGDADMEAGQDDANESPEGMNNFGDMNQMQMMMAMQNGMNPAAFGSFPMMGMGMGMDPMAMQNMFMNGGFGTQGMGMNGMNMNMGMNGFNGGNNDWNGQQSWNVGQDNFNPNAAGMGNGDFGNFNSGFRNGYNSGNFGHNQYNDFGRGGYGFRGQGRGRGFYNRGFGRGYHQGFNPRHYGQEMWAQQISQENGGGMGLNTTGNNSAVETQNASNTDEFGRTVRPDSEQLGHAVELTGVDSQGDVQNGGVAPTEAGTDDNMQNGDPSSTDPYPRARSQGTGSLPPTAAPDVPLNAPTGPKAMRQGLPNTSALHLRARGFMTDQQSPISGPNGSVVQSPLEEVPPSRSSSRHEKDSDRRHPERGGRDHDHNEDKSRDYGGDRTRSRSRSRSRDRKESRRHRRHRSESATGDEREGDHRRRKHKSRRPTRDDDDHKSRSKDEKPDRSRSVSPERERERDHKRSSHRSHRDRDRDRERDSDYDRHDRHKKSSHRSRHDHDRDRSRDRDRDRDRGDKDRKERHRDRDRERDRDREYRHRSRKTSAEPPTPVEGTDKDFNPPSGPRSGMSIKGVSSKSGAVESKGSSGSKSSRSHIRESESSSRRPSKASASGSKGAAASSSSSGKDPHTLEREARDRERLLKEAQRMAGLTSLASLKRTRDAGDDRGSDRRRKSRRSEAVYDDEEERMRRLEAEREGDRWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2M4</accession>
    <name>A0ABR1X2M4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Amino-acid transporter arg-13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_004581</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672514.1">
        <property type="nucleotide sequence ID" value="XM_066808896.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041956"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF31">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="30"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="131"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="245"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8089620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="36869" checksum="4FF8ECCD2CD45D45" modified="2025-10-08" version="1">MATSTDYVTQSAASQSQATHSAGEKRKAGMEAIEDIVYGSAAGVIGKYIEYPFDTVKVRLQSQPDHLPLRYHGPLDCFRQSIRADGFLGLYRGISAPLVGAAAETSSLFFFERLGRETVYASGLYARDTVLPLPALWFTGAFSGTFTSFVLTPIELVKCKIQVPAPSTGGIRQQPPGVLSVIKDVYKHDGFRGFWHGQMGTFLREAGGCAAWFGSKETTTKLFYVLNERGIKTQAEKDVLRTESLPLWQQAIAGASAGMSYNFLFFPADTIKSRMQTTAVGGTAVKKTFMQEGRALWHQHGLRGMYRGCGITVLRSAPSSAFIFMVYDGLKKYFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2Q2</accession>
    <name>A0ABR1X2Q2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translation machinery associated TMA7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672544.1">
        <property type="nucleotide sequence ID" value="XM_066808926.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041986"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015157">
        <property type="entry name" value="TMA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28632">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09072">
        <property type="entry name" value="TMA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="7148" checksum="4ABDE3BDC417B5EC" modified="2025-10-08" version="1">MGGANREGGKVKPLKAPKKVAKDLDDEDKAFQEKQRADAKARAEMAAKAKGKGPLNAGTQGIKKSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2V6</accession>
    <name>A0ABR1X2V6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Forkhead domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004709</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672642.1">
        <property type="nucleotide sequence ID" value="XM_066809024.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042084"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045178">
        <property type="entry name" value="Fhl1/FHA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712:SF29">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="339"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Fork-head" evidence="6">
        <location>
            <begin position="731"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="3">
        <location>
            <begin position="731"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="263"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="455"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="644"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="810"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="856"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="917"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1077"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1185"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1315"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="423"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="479"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="644"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="697"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="865"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="944"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1185"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1219"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1238"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1315"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1338"/>
            <end position="1348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1411" mass="150954" checksum="B90DEB6CF8B6C532" modified="2025-10-08" version="1">MTSFSANATADRIAPPASTSEVDSPPRPFPLLDVNAMDISGLNHDDDPLYAPPTKPPTVTAVQSTNGDNAAEHDLPNLSESAQAAMPLSASAPLNPMADFSSIKANLAMGLDKLQTTGLPSGSKDRERAAVATTDDDIAYNARSTSNARMMSRHASITSADPNAFILSMPQGNNTQLSGDYPTAIAPSEISLQASFTQESDALTGSADVASASASASQKLESFARIEFADSVFQMTTYAVIIGRDQRALDQARRDEYREERYRRRVEENERQGLPPPTPLGKDRGNSVNRMPSSAASVQQGNTNDQDEIVKSNRQYVSHTEGVAAVDLGTVQPSPSHIPFVGIHSPGPNIAMKTKAISRNHLKIQFNEKKGVFEAVSLHRNGFFCDDVFYGSEHGPVTIRSGDRFQIKDVGFLFVINGVERGKTGGEDLHEEEASSKRYSVGGKEMSFDFEHSDHEKFHDTSDELSDLGDISTPPAGSDDADDADDADDVEDAEEAEDAEEVEEAEDTAMAMEPPSEPPLAPAEPEPQTIQPDRAGDVVMQSAESAFEDHEEESIERRLQTALSADLDLGLDTGLDTTFENTELDVGDAGLDTSYDMDLDSRFDNGIPPEYAGLPIPQTAWSRAAPKDGIMSKRERRLLKKQMLEDAKKVQPQEPLGEKIKRPVGRPRKNPLPENGDRPEKRKYTKRKKEDGEEGSDAEKRAKEKKDKKVRPKSPPLELNREDFTDEQLQKPSKNYGVLIDEALTAGPVEGLHLKQIYKRITAKYPWFYFHAETKGWESSVRHNLLGNDAFKKDDQTGLWSRVPGVELDAGKKRKATTPERSLGPPSMQPHQMAHQQHYYQGSNYMQQGGMHYAHGLPGQGYTGGNQHQNGYHTSSHNAPNPVVQGTTTAHQSYPGQSHNHAPITTTTAPNLAIARQPGPQQQQGAYNSPYARPTPPANPLPKTENTNYNPQTSHIPPAPANATYTTQANQNATSLGANGTSSRVPLSAEVQKVIADWKKQILTTISKSTDAAKAEQIIDTSINRALGIPAAATLPGFEAVETTLVNAVQGKIRDAQNQARTAATATATAAAAAAAAPTTPAAPGRQPSLAPAASPAAAKAPTSSAPSSLEATIQARIKVFRVPILAAFRKRTEHAETIVDTAIKRAQGLPHQDIMPGWEDADRLIVENVHKIITEVRKNHGLQTSAVSPSIQPARSTQEGSAHKIQSASPAPLPPAMTSATSTGQSSSNHNANAHPPAVPHTSPPPVVNNPSAPRPAMPQLSRPGISVARPSKARNVTIGDFPVRYSIQCPGTTSVPSHTSSCTASFSTASTCTASSGTAGPDKSGPGKSGSGTTGSGTASHGTSTSARGDSLTSTKVCNATANLDTTTSRADTKTDTGTRDNDFACAKVLHVTAGPSVDFSFAADFEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X327</accession>
    <name>A0ABR1X327_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672679.1">
        <property type="nucleotide sequence ID" value="XM_066809061.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042121"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="208" mass="23332" checksum="202376988131EA0A" modified="2025-10-08" version="1">MAENPSTATLVPELPPQPELPPQPELARDRTSDDRPPESLNEVPAPPRKLKKEESAERVLIWRDEVDASMVTCACSLMTRRQPVTAWCPECAAPFEGLAYTRFRDGDEGLTRLPSGRPSIANVWPVFSLRDRDTTYRHRLGPRGTAPLFPTNELKILGHKLAAKTKLDRLFRSKQPEPEPYAPRNTATCPAPWPSWSPNTTRLSTRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X454</accession>
    <name>A0ABR1X454_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_005142</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the pacC/RIM101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673075.1">
        <property type="nucleotide sequence ID" value="XM_066809457.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042517"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050806">
        <property type="entry name" value="pacC/RIM101"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257:SF1">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC_RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="93"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="356"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="544"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="363"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="380"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="479"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="498"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8090181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="579" mass="62678" checksum="DDCEBAB22AB6B2D8" modified="2025-10-08" version="1">MQQQRTPEHVGESSSNTPAPSTTASSATTTTTANSTSSAPAAAAAPAAASPSADDTLVCRWNSCLERFPTAENLYEHICERHVGRKSTNNLNLTCQWNSCRTTTVKRDHITSHIRVHVPLKPHKCDFCGKSFKRPQDLKKHVKTHADDSVLVRSPEGHGGMNAAYRGPTKAPSSYYDHNGQMRTNSAAFGQPHPGSHPSSYYQHHAPPSFGGGMYYQPLGGRGEHMYHAAPDSYDSRKRTFDALNEFFGDAKRRHLDPASYAQVGQRLMPLHGALPIHGGHMGEYMPAPAMVGVDGGHASQHGGPYTQHYSLPPMPHIRTKADLIQIDQVLEQMQSTVYESSNTAAAAGVHQPGSHYVPLYRPSHSPPHSGGHSHAPAYSQGSMASPLTAVSSTHSNGTPAVTPPSSSMSYTSGHSPSASSSGLSPTTRHSSTASGLYPTLPAVSAGFPGQSATSTLGPSFDSDPRRRYSGGMLQRSNRAIDEREREREREKSTTPRASESAVSSVSSPSAESESENREDQEYEAWLENVRVIEYLREYVIDRLKRKEYETGSPKSASDDMDVDSPPKESLYPPLPPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4E4</accession>
    <name>A0ABR1X4E4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673123.1">
        <property type="nucleotide sequence ID" value="XM_066809505.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042565"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="171" mass="20038" checksum="14E3ADBE8AE3CC8B" modified="2025-10-08" version="1">MKRQQSRWTAVNSANLGDDDDEDVPQQQPEKTQEEKEEEEEQLQHDIAQRSLDYSATATIKRGRRRSSNNNGKKSGTVWAGMVEPLLREDKEHNRQLEEGLKRRQRERENQQAGAPRKEKTPEEKRRIYNEKQRERRARIKKEKEEEEKRRQSGEDTLDTTLVVAAATVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4K5</accession>
    <name>A0ABR1X4K5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nonsense-mediated mRNA decay factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005248</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in nonsense-mediated mRNA decay.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673181.1">
        <property type="nucleotide sequence ID" value="XM_066809563.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042623"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019458">
        <property type="entry name" value="Est1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF36">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10374">
        <property type="entry name" value="EST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomerase activating protein Est1-like N-terminal" evidence="4">
        <location>
            <begin position="74"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="DNA/RNA-binding" evidence="3">
        <location>
            <begin position="201"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="632"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="716"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="882"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="951"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="721"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU369098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8090287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1120" mass="122106" checksum="8A6F9E59B9F26E5E" modified="2025-10-08" version="1">MAHDMRKVAAARWMEASSFREKIQQKIEELQSIEPKVSVNYTARLEQIETLMQQYRLACVTAIFADFAFSQKQDIETVLWSTHTMFNNTYRRVLSRIGDRSQVVQKRKVDKLYRDFLKYSQLFYKGYVQRLAGSYDIPELRQAAHGLEVEPQGVQIPGALPAAMRAALVNACYMTLVRLGDLARYRCQHAEKATKGSFDTALTYYGLASMLDPDDGTCHHQMAVLHQIQGQQLEIIYRFHRSISIDKPYELGPGNLQKAFDRHQNQSNSRRGPAKDPAEAIVSWFVKLHAHYAKGKKFSVQKELEDEVLHQLEMSVKGEGNEDVVLKMILINIAAYDIAKENLKNPDKWSMEGSQTCQYILNFNLHTILVLVRQLLTALQTDSGITLASNQEDGSAECTVEFSSSLSKLISLCRVSITWLYVTRSDLKEYQDHLDQKAREDIHRLLAEVLTRLLPHALVNNNAAQSTYLLPEDTEIIGLRPLTDEQLPLFIHDKITGVAGSTHCRKALKPRKEVTRPHFKPRTETLWRIRDILLCGIYLAASHESPLIMTGGPDGSRTWVYPDGPAKDLGSAQDQRAQSMRPLGETDLSNLFEDLTMTSGQQTDSVPVATAQGSLEDLLSPAVLAANSPMRKGVLSSKPNGTPARATPKRTQAKAAARHSEAEELDMDQMVNDMVDDLTGNGDENDDSLLQPSSALADTSYGMNSSTANEIFGQLGLGPSHSLSPENGPNSRAAQSVSPTGALTNSIPSHPWGYSLSASTTAPDSSLHSMGNGRDIPRTITSPNPALGGSVGAFEHMISPTYGSYRGAESLGPAHPTTSGFASGLGSISGNSRISPTAYGQMEVGSVGASTGTASPDFANAQRNLARDRLASDLFAQYGASAAQKSPAMNPSVPGIFRSGHSPLPGVRRTDSMSPSMADNRSLLEALKSGHARDKASSNDQLLAQLGGLQAGVGRPQQPRRSGPIDMNNHNGQRQPGYASPLAGGYSNQFPLSPNAVGSPHQRSQGSLGSFEGQLSSLNYGENSVARTGSPWTFSHPSQIWTGTPATAAQPAQVGMVECNGNYYNSSTAFGRSGEGNNREDPTHFRNKIKQFGGAEKASAYDRAILESALTDTHNKPPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4T6</accession>
    <name>A0ABR1X4T6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005376</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673309.1">
        <property type="nucleotide sequence ID" value="XM_066809691.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042751"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF52">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G11820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="92"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="9"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8090415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="539" mass="58915" checksum="8B51DDCA6B49129C" modified="2025-10-08" version="1">MSAFFASMGGVAGAPSGHAHVSDNKNAGPVHPRDFTATTDPTVTRQDVANDNSEKGSLPSPTSSVDDAGNEQQHVIDPVAERRLLRKIDLSVYPILFVVYMMSFLDRINISNAKIQGMAVDLDLLEGNRFNIALFIYFIPYILLEVPSNMVIRKVRPSWYLAGLMACWGIINMCMGFVQTYQGLVVLRFFLGAFEAGVMPGIIYLTSMYYKRHEFQTRMSFFFCSTLIGGAFGGLLAYAIAHLGGSHGLAAWRWIYIIEGAITAGIALLASFLIVDWPEQCRFLTSAEKDLLRRRLAEDGAEQASMDTLNRQAIRLILRDYKIWLGSLVYMGVGVTGYATTFFMPTILLEFGWLAADAQARTIPVYLVSAAGMLLAAWASDRLKHRSGFILAGCAIATVGYAMLLGQAALSRDAKFAAVFLVSLGGYLATPIGLAWLANNLSGHWKRAFGSGTQVMLGNVAGIIASNIFLAGEAPRYPTGYGVALGMTWLGALATAALALGLWLENRKRDRGGRDDRLLLPEEEVRNLGDDHPSFRFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4T8</accession>
    <name>A0ABR1X4T8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005325</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673258.1">
        <property type="nucleotide sequence ID" value="XM_066809640.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042700"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="397"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8090364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="479" mass="53854" checksum="DBE1E85A27DF9BE3" modified="2025-10-08" version="1">MNWIQDDTQISTIDLENVFKYEEKETTVITWSTNDTSPVVHQLEDSAWEGWLQNKIRAPSPKCSSCKQAKDWMNFLYCVDKTWILDLPAPAGNLSPSTSGRKPGSLTALGGQRYLRTVPFSRATFRQITDGFRIHGSISTVISRADVPVFSSTQVQMDGDTAYVYNCRSSNDWGKDLALTVTHLPDSQTTFCIMFGCDKSIEEAVISRLSAIGSEISHPLIMPAILVELERLRHKRITAQAIASLETNIAELDFDTDKLDEESGPGTVGDRNSVRRSTWLDTAYLQNGLVNWCLQLGKLRNCVVMFDGDNQPITVASAEITSNNLPSYVELYQANRSKGTGRKIVARIEAIEEEYAQIVRDCKMRLEGMSMATQWAQGETNMAIAKATSRDSKHMRAIAFITMIFLPGTFLAGVFSMSFFNWQTSDASLVSTYFWVYVVIAVFLTLLTVGSWWVSTTHRRKKIRTGFNDKIRKLQELPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8X5</accession>
    <name>A0ABR1X8X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismatase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673851.1">
        <property type="nucleotide sequence ID" value="XM_066806555.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039615"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8378" checksum="FD203C8B1A908334" modified="2025-10-08" version="1">MRITEPRVIPMVKTASHPAVVIEPRRTVLALVDYQNLFLHPSLTPAAEAGRAAASGPAVDMIRAFRKGGMKVAWVNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X965</accession>
    <name>A0ABR1X965_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 6">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002357</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673968.1">
        <property type="nucleotide sequence ID" value="XM_066806672.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039732"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00883">
        <property type="entry name" value="beta_CA_cladeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002:SF51">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8091996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="297" mass="33408" checksum="970451776C2CD0DD" modified="2025-10-08" version="1">MSSLRLSNSLLSTTRHHLTTSRIIRPTILTKSSRLTSAAAVTFTPRYCSSSASSSGSNKDSSPSPSSHKDSAWRKMSDEKQIPHYLKQDHDRVFDHNRAWATAQETRDPGYFAKLSEGQTPDYLWIGCSDSRIPAEQIAGLAPGEAFVHRNIANLVPNNDLNVMAVLEYAVRHLHVKHIVVCGHYGCGGVKAAMTAKDLGILNPWLRNIRDVYRLHEAELDTIEDETERYNRLVELNVVEQCRNVVKMAAVQQSYAENTYPIVHGWVFGFHDGLLKDLNVDFESMLAKIQKIYNLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X999</accession>
    <name>A0ABR1X999_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase III transcription factor tfiiic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673927.1">
        <property type="nucleotide sequence ID" value="XM_066806631.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039691"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039340">
        <property type="entry name" value="Tfc4/TFIIIC-102/Sfc4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23082:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23082">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="456"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="877"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="531"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="573"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1054" mass="120573" checksum="DDE24E8A9BC7CD58" modified="2025-10-08" version="1">MATRRSRRFCPISSAGAVPRGPSVPPEGLRVEEPAEENDALLEAQKQALGTFEDSVRNFVNARDIKKAVKFGLDDDPQAAADKAPRIVKKRGPRKAAEPTGDVKMRLNYATTAYMEGRLDDALNYVEDAIRINGEIHRAWTLLASILQDRGEVKQGLLALVCAAHLEPKIVTGWVHCAQLALQLLDSCPEDFEDVSKIGLMALSQAIRIEPDNIATRLGRADLYFARESYKHAIGEYQLILEQTPYDLAVLRGLVEAAVQLSMTRKKGTEKPQYAAKEAYQRGIEHYRSEFELGSHDPNLPLTWDDFIMYIELLHHLKQWEDVISQTKLYARWLLGRRDESFWDSIQDDREWDNYDHRRNEMIPDYAPGKHPMESYGLGLPLRLRAKLAICRLHLKQDDEAMHHLEWFEPIELVPDDEQYSDIFAEIAGALYEHQHFPRALRFYDPLRHQEGYLDAAQLYQVGKCYLEAGNKRDAEDYFAAALDAEESTIDTRISARYELAKMYEEARQGEEAYILVNEAMELERDRDENLLYGDGDGAYRPRRPLKAKRKPAGPRKPRVKGEKASRPSGPRRPREPKEPRTGPKGPYKRRVRIFALNEDREREENARSAHLATKWEIVRAGNHQTEELSGGPGEEWMAAAKELIEDFCSFKAFFPWERYLVNIGLKQDKAGLSSTNPTLLKMAQRLKDSQSLPEPSFAYYIDSSQAAEQGNRVQSNLEKRVHENPVEYRDVTFPEWLDLFVGYALALAQVGQTKEAYKICESAKDANVFFEDTANLFLIHIAMAACALRARDEEKCVEVARYIMSKNQFSTDGYRVYAAICRLCSSTAGWYADSRVQKFTLRQIKMMDAALLPPEQKDKSLEGQDVKVYPGKELDATLLMMYGHILFVSNSFTYALNYFIRAHAREPNNPMVNISIGLAYVHYSLKRQAENRQYLIVQGLTFLHKYYDQRLASAENCSMQRQEAHYNLARSYHQLGLTHLAIQYYRLVLREIEANPPAEKEEEMGEEGERGVIMRRRKMENLAQEAAYNIQNCCLIGGDMIAARSVAGQHLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9A2</accession>
    <name>A0ABR1X9A2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002371</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673982.1">
        <property type="nucleotide sequence ID" value="XM_066806686.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039746"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF119">
        <property type="entry name" value="NUCLEAR RNA-BINDING PROTEIN SART-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="73"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="224"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="154"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8092010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="323" mass="35274" checksum="364D332BAB7E8494" modified="2025-10-08" version="1">MSDPAGNWRDASSWRSPSAGGNPPSSTWRQRDRNNPSNPTQGGSRNNSSRSNDRPARGGQDDSATAQAIAEGRRIYLGNLVYSAKPEDVEAMLEEHGCKGPEYKNTHISVDPFSGRNPGYCFVEFATKEAADAAMTGLEGMPLFDRPVKCRPCLPKGAPRRTDSDGNSPAADGERYERRSDRPREGGANPSRWGNWGGSGEREGGRSSIPTKTYERSKAQEEGRQVYVGGLPRMLDQTENDVEMRELFNGFEVELVSKRISPKTPSAPGTDERRNFCFLDFASADQAQAAVNALNGSEHRGASIKVSIAVPRTERAPTQSYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9S7</accession>
    <name>A0ABR1X9S7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FMN-linked oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674131.1">
        <property type="nucleotide sequence ID" value="XM_066804358.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037418"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="339" mass="37605" checksum="6A87E7CCADDA47C8" modified="2025-10-08" version="1">MVKEYYEQRASVPGTLLITEATFISPQAGGYPNVPGIYTPEQIRAWKDVTDAVHAKGSFIWVQLWALGRVANPDALKKENPAFKVKGASPLPEAEGKTVPEEMTEQEIQDFVRDYAQAARNAVELAGFDGVEIHGANGYLIDQFTQDVSNQRTDAYGGSIENRSRFALEVAKAVVEAPGVGPERVGIRLSPWSPFQGMKMADPVPQFTHLIQGLKELKLAYLHVVESRVGGNLDVADTKSAEKVEFAVQAWDRTSPVFIAGGFTPESAREVVDAEYQDHEVVVVFGRYFISTPDLPFRVQKGIELTPYDRDTFYNAMEEKGYTTYPFSQEFLQSQKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA57</accession>
    <name>A0ABR1XA57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674363.1">
        <property type="nucleotide sequence ID" value="XM_066804590.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037650"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053018">
        <property type="entry name" value="Elsinochrome_Biosynth-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="504" mass="56288" checksum="C67606AB815E7B61" modified="2025-10-08" version="1">MDSHTSDTPFPTVTSMYTSVGLCTPDSTTDRIGILFKSTYQSQSLRIAPGWQNATRESIPIRTYQGWGVVVAFLLSTYLVLALILGAYCFGALPEGLVRRPDRQLFFARRPGPNERWQRIFEEVVLIFSDQQLLTGIGVLVAGYVQVVNADLSAYHWNSVVYLAWLSSTVHLMSLSVLRGRLKRNKLALTVRICAIMLVFILLVAALWPTTMIVEHPATPVRCQWIARKIPTVGSSMNTFVSYLTLVGTFFWKLGQFPDRSRGWLHFWGRAWLECAMETAARHSLQTRLRTPWSMAKYRAITTFYVIFVAHMELLESFMFTITLLAYTLVWGTVNLTQRTEVTYPYGLESFGGELDEAEKEMGFGQILALLLLAQPVLAALDTLNSTVAPFELDVPSTVANMTSGQRRIPALGYTAAPTSAFQEPPAAKSRTLSEMIMRMVSTSAAMPMVDSSQHPAAVPMTFRARPGGRRWESPAAVPAQYEKGATTRRIAYGNRYRGDSTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAP5</accession>
    <name>A0ABR1XAP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674493.1">
        <property type="nucleotide sequence ID" value="XM_066804720.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037780"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="269" mass="29307" checksum="D24F2BADF19F88E6" modified="2025-10-08" version="1">MGQWKQHTTLSHADLIPWKSAQCPICLEDMPKGALLASSHLAHHLEHIAFIGFPTPPDSADGVDRVSNNPLLVASSTNDTKQTDSTTMQAPSKRRFWEYPWLKHTSAPKLGTSRSNSADFGNRKAGSNETDNNPTTASKGVTKDKQPAQEGEEFKDLIDRLKNLFLDHPETPEQPPGSNRGDQERTAPTSKDPTQGSSPHSTDPTLKSSPPVTLPSEASPTIPRNAPVASRQQKSVRIDAVERRGASSYGDDSRFSMATWFCVSIEIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAV6</accession>
    <name>A0ABR1XAV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000476</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674564.1">
        <property type="nucleotide sequence ID" value="XM_066804791.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037851"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="196"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="505"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="69"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="742" mass="82265" checksum="2D08A94D520BA8B5" modified="2025-10-08" version="1">MAPRLTQRLDRDVYQILRKLEDDHERNSSKPAKFTIDGVYNMIKKSNSSVGREKKRPLEESIERVMRFRKEERAEVDEDETMEDSPAEPPTPKQTNPSLMNKQIAKSWNVARRERASSPEATVESSISMNERLPNGEPKLKRRRAEKAEKDRTPPNGLSLFNLGGMDDAIEQLVRHVARPIVRAKKWMEKAKGAEPTRGVLLHGPPGCGKTVLANTFAAELGIPFIPVSAPSLVAGMSGESEKQIRNLYEEAKSLAPCLVFIDEIDAIMGKRDNAQREMEKRIVAQMLTCMDELSLEKTGGKAVVTIAATNRPDSIDPALRRAGRFNLEINIGVPNELSRIQILKALTKNYNLAESVDLTALAKLTPGFVGADLQDVVSQAVSDMLERADESRIQKAMEDNPAPENGFVEATPKMKFMMHQLSALKSLFDDTDFEDDESYLVSQQHLLDAITRVQPSAKREGFSTIPDTTWDQVGALKAVQKELSLAIIRPIDTPELFSKVGWRSPSGVLLWGPPGCGKTLLAKAVANEAKANFISIKGPELLNKFVGESERAVRQVFTRARSSAPCILFFDELDALVPKRGDAIAESSARVVNMLLTELDGMNSRAGVYIIGATNRPDMIDPAILRPGRLGNNIFVDLPDEDGLVEILKTRIRTVLPESTQEQLEALEPVARDPRCKGFSGADIENLHIAAAKAAVERWDEDKGSIEITRADWDVALSKIKPSVSEKSADHFRRLQNKGWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB47</accession>
    <name>A0ABR1XB47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000539</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674627.1">
        <property type="nucleotide sequence ID" value="XM_066804854.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037914"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF162">
        <property type="entry name" value="SATRATOXIN BIOSYNTHESIS SC1 CLUSTER PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="47"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="331" mass="35800" checksum="E8F3CFC1E82FE182" modified="2025-10-08" version="1">MSNPKTPDETHPSTARVDRDTLLGAIWSLTSIAILLVAAHLSIRLCYSHRRLFADDYLAVLALLLLISNSVVMTLMAPTMYEVIVVSAGPVVPPPPTFLDDAAYYLELQFASTVLFWSCLWAVKGCFLVFFGRLARPLKWPRAWIAIVIFTVAAYCASIVTSLVLKVECQGPLNIYRSAVSLRFSTAVDVISDVLITCLPVYLTVGLQMSAGQKVGLVAVLSLGGIITVFALVRVVVTGDDATRLAEISWLALWSAVESSVASMAGQTTKIYTSKSLTSRSGSGGPQVVMAEEAELDEFTGRIFSRKAIVARAFVVEVGSRTASQERILDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBL9</accession>
    <name>A0ABR1XBL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674832.1">
        <property type="nucleotide sequence ID" value="XM_066805059.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038119"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="170" mass="19763" checksum="CB1A1BB69A9AEA89" modified="2025-10-08" version="1">MYEQGSLDRLGWEALCGQIVKEVWLMPLHVPELPPLIPPGTSVWCIALQLLGERMIVLYPEPSENETEPMALVMCRVYITPEELQRRDTELRLTMRGSGYQFGNSLFGNIRVGDLLQALVRSGIGYYRLKQRHGTRFWLCLVWFQWFNFMENGRDGLPEIIEHMHDTPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC77</accession>
    <name>A0ABR1XC77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(m1A58)-methyltransferase subunit TRM6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000930</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRM6/GCD10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675018.1">
        <property type="nucleotide sequence ID" value="XM_066805245.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038305"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017423">
        <property type="entry name" value="TRM6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945:SF0">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04189">
        <property type="entry name" value="Gcd10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="284"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="611" mass="68058" checksum="3C715F03D1B5D789" modified="2025-10-08" version="1">MHSLVEPNAWVAIKLPSENLRVLQLTPNTTISLGKYGSFPSNLIIHRPYHITYELEDKKDNESFNRLRIVPASELYSDILSSSSFLSPDSASPGPEGDDTEDAIPTGVEYALVDADSGAVVAKTDRAELDAEARQSLTMEQIEELKKDVTDAGRDIITKLMLSHSAISQKTEYSLAKYKLLKTKKYIRRFCVLPLDVSMLDYWLLEEKDPAKIMDLREEMIGLLGCWANVHFGGESRCLNEEEQEAAANGTNTVTKPEDSTGRWLVVDDTGGLLVAAMAERMGVLYPPEKDEEEVNPPQKRRRDSESQPEPAGGEGESEPQAQPAEQTQPPSGGEASGQEHIVTKRVKYPTGDPRHKDDLAVPYANCNTMTLLHHNSQPNLSFLRYYDFDNTNPTQSLTHPLARHLMTLSWLQLLDPLADSTYANEPPSVSSDELKTWKANRRGNYHRKRRRWARIRHVVDRTRGGGFSGLVVASTMDPTSIMRHAVPLLAGGAPIAIYSQTPEPLTALMDCYSVARRAAWISDPPEEAIGKTTEELEQWAGTDEFPLNPSLVLGAAMQTSRVRKWQVLPGRTHPLMTSKGRRRGLYIYGLAGEACRGQGRGERKRQDEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCD0</accession>
    <name>A0ABR1XCD0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675105.1">
        <property type="nucleotide sequence ID" value="XM_066805332.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038392"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="63" mass="7026" checksum="01EF9AF6922222AC" modified="2025-10-08" version="1">MLSYYIRYPSAMVSSKTGPFIPNTCALHIAVAVSHKLVSRTPTLQSGMQQPQGSSAYLQRWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD91</accession>
    <name>A0ABR1XD91_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Replication factor C subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_001248</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the activator 1 large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675336.1">
        <property type="nucleotide sequence ID" value="XM_066805563.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038623"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17752">
        <property type="entry name" value="BRCT_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013725">
        <property type="entry name" value="DNA_replication_fac_RFC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012178">
        <property type="entry name" value="RFC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF6">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25361">
        <property type="entry name" value="AAA_lid_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08519">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036578">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="9">
        <location>
            <begin position="305"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="389"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="944"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="944"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="974"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1011"/>
            <end position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR036578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8094563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1021" mass="112815" checksum="0CBD0FADF69D5697" modified="2025-10-08" version="1">MSDIRSFFGPKGGAAPKPAAKPAPKKAEEDTSKRRGKARKVVDEDSDDEVAPEPKKPVTRSTPKKKTAEKVVKGTETTASEYFASSKSKPKPAAKAEAKPVPEVKTEVRASPRNKKPAVKEEPAPAKKTRGATFKRYDMNDEEDAFMDDGEGGDDIFAADAKSRNKRKNDDYVEEESEEEFLPKSKRLASRTKREADDEDDKPIVTKSTKAAITSKKRKTPEAESDEEDEEPASKKKPAPKKPRAPRAKKEAEPEDSSIQAILDDIPTVRAPTPPPQDLNVKYDWRKGQAASGPPPNPTDDVPEGEEDCLTGLNFVFTGQLTGIAREEAQELVKRYGGKVTGQPSSKTSYVVLGVDAGPSKLAKIKANNIKTIDENGLFELIRRLPAGGGTGKGAEKVREKRQKEEEKVKQQAAEMEREEKARKLEAEKARKLAAARGVTGPAPAAAPPAAQLWTSKYAPTQPQHICGNKAAVEKIQKWLRDWAKSRKYDFQKRGIGKTTAAHLAAKLEGFDVLEQNASDTRSKKLVESGVSEVMNNTSLSGYFAGDGKKVDKQKKNIVLVMDEVDGMSAGDRGGVGALAKFCKKTEVPMILICNERRLPKMKPFDFVALDIPFRRPTIEQIRSRMMTVSHREGLKLTPQVLDALIEGSNRDIRQIINMMSTIKLDQTSMDFDQSKDMSKAWEKSVILKPWDICQKMLGGGLFSPASKATLNDKIQLYFNDHEFSYLMIQENYLRAKPAALGGGHKREQDLKALELMDKAAESISDGDLVDRMIHGPQQHWSLMPTHAVFSTVRPASFIAGSLMGSTFTSWLGNNSKYGKLGRYTREIHSHMRLRSSGDANEVRQQYLPVLWTQLVNRLQVEGKEAADEVIDLMDSYFLTREDFDSIKELGVGPQDEKDVNIDTQAKSAFTRLYNSRSHPVPFMKASSVAEPKKVAKEVPDLEEAIEEEDEGDAAEPAEANDDDGDITKDKYIKQPKAKPKRAPKKAAKAAKDDEDDDEDVKPAKGKGRAKAGVSKSKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDP7</accession>
    <name>A0ABR1XDP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_001481</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675569.1">
        <property type="nucleotide sequence ID" value="XM_066805796.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038856"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050660">
        <property type="entry name" value="NEK_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671:SF98">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="40"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8094796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="349" mass="39870" checksum="0CF2CB966F3038A4" modified="2025-10-08" version="1">MSTADLRKYRQAGVFLPHYRGNRASADRENARGIVADKGFLFVKELGGDKLFLVQSLANNRLYVNKILVRTDDDQNGDFKTQLPPELRFSIIGAPGPGNVQFDYLIDETYFTKLDYWKRLNAKAYYLYFQFANGGTLEQLIEKYRELGDEVPEHFIWHVAVELGEALKYLQRGDQSLGRPPRRWPRIYHRDLVPNNVFVNYAPVGQSRGNRGTVKNAFPEIVLGDFGLAADLLPSVHFDDPGLAGHPASNRPNDWEDVHYYGGILRRLFMASIDEDDYLNPDVITPEQFTVRAANTQGLPAGRRRYSATLEAWLQVFEWPNMDSSDIEQSQGQWCLGAKLGKLYHLLHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE35</accession>
    <name>A0ABR1XE35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F-box domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675655.1">
        <property type="nucleotide sequence ID" value="XM_066805882.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038942"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="224" mass="24668" checksum="18265BEAB47D2698" modified="2025-10-08" version="1">MPPLVTCRPRTAFLYFLQLREIVLPLDVFQCHLVDRASRVDKSIEDVVEEDPETLGLRLGNFLPGSVAQLTLSSQGQVPHDRVLAVLFHDFGALKDMRLPDMEQIIIECQLDYDPDPAFQAICEGLESEVGLSGVALHLETEPLGPELEWPGSEKFESFIGFDDPPQDEEDGAATHAIKNAFEDIGLGLGSSLPPSQGPSTSRSPYSLPTVEVAPLRFRRQVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE62</accession>
    <name>A0ABR1XE62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001564</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675652.1">
        <property type="nucleotide sequence ID" value="XM_066805879.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038939"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="355" mass="40813" checksum="E4F8FDF5FCA723BF" modified="2025-10-08" version="1">MEGQRLPIGFRVGFNDEDIDFGSQPVSSASSARSFSTASSCDPYTPISGRSTPSRHQPPRSAMEDFEPVICSSSMGYEMTPPSSDLSGYYPVDVKSEYAPSSMSSENMISTPMRKLHLQDQMIDFDFNHVLGNPMQPPWHLDRPPMALSPPMGPTPSYTFNQEYDEYPPWPPQMTESHPLDCNFYSIPEPSAMHIHLDTRANAPSSVLRSNVKRKVYMDNAQRRGTSLQKVHGRNEAKKDTSEEQIPVSKIPKAMHVCDFPGCEKQTAFKRREHLRRHQNTKHGLGVEVSCEFCPKKFNRRDNWRQHLRLHTEPNRPMTRTNYNKEAVHKYEEERNNTKRRRPRMKKQDTPVGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE66</accession>
    <name>A0ABR1XE66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Smg-4/UPF3 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001658</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RENT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675746.1">
        <property type="nucleotide sequence ID" value="XM_066805973.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039033"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039722">
        <property type="entry name" value="Upf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005120">
        <property type="entry name" value="UPF3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112:SF0">
        <property type="entry name" value="FI21285P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112">
        <property type="entry name" value="UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03467">
        <property type="entry name" value="Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="507"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="211"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="322"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="584"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="231"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="437"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="475"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="584"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="664" mass="69913" checksum="FD1E875CD7BBF09A" modified="2025-10-08" version="1">MASVASSRKANGTNATENAGKSDAPKKTKAPSTSKKVKIRRLPPGITADECWSILGDEWKVDSGKVDWIRFDPGKVANGPFKESKPATAYLRLIDATQEFANLQQLVRTPEIWRDAKETFNDPCLRAPPELVVAEFQKVAMGKTRIDPRQGTIDTDPTYMAFLQQLTEPITSIRDAEIGADDDATAKDKPKVTSTPLVTFIKEKKEAKAKEAAAAKSAKQHARQESSGVGKNKEADDGKKKGKGKESSKPSEKTEKASDKGKEKDKQPVKIMTKKAAQQEAVEAANAVADQIATSKAVDEGGAPKSRRAGIAAAAKLLQRDLGLSPGSAHRRARQDAAKADTTTKPEPAKAPEKEEEKPKEKEKGKEKERERKGKNADKEKEKEKEEPAVPTGPKGQSTEGSRRTRGKGKAAAATESTKGKAAAETSKPTTGPIILLKKENTKKEEAAPAKPASPTAPAQSSTASNTTPAPPTGPKAASGGKGAASSNKANQSQKKGAAQQPAAGATRAFVKHANPSQGVTEALLKQAMEGFGTVTFVEIDKRKGFAYVDFGDAAALAKAIAASPVTIAQGTVQVLERKDKKPAAATPAAAATPAAAPSTSAEKAAPEAPAAAATPTASEKPKRGREAAVDAAVVVAKMGQMLPRGRDLLLLLRLPEELRTDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEI5</accession>
    <name>A0ABR1XEI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitochondrial export translocase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001717</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675805.1">
        <property type="nucleotide sequence ID" value="XM_066806032.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039092"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF65">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8095032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="390" mass="42310" checksum="D8CB5D7CF07AB108" modified="2025-10-08" version="1">MSLHLHRHFAQATTSSALLKRSFIIHPHSNSSFKRLQPHLQQKQQHGSQRRTLFTESVQAAVQGSQALILGAHAATGLPWAAVIPLIAVSVNAVFRLPFSAYSQKLLQRRKRVEPLLQAWRERVIKDVVVRERTDPAKAKAKVEDRLKTIQRRVYSALGLRQWRFYLSLTSFPVWLLALDGIRRVCGGQKGVLLGLLTGEKSLEAGSAAGQAGADASSAAAVATPTTGGPVAQSISAAVDTTIPEITSAASTAVGPTTSAVDPSLATEGMLWFTDLTVADPYHILPVALVGMLMLNLIPKNQAARSAILGSGLYRGVIYVMPLGTFVLMDMPAALHLYWLSSAAAHFVFGQILNRMMPLDQKPIEKCKGISSMVISPKSKPGQKDWEKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEJ8</accession>
    <name>A0ABR1XEJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_001739</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675827.1">
        <property type="nucleotide sequence ID" value="XM_066806054.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039114"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF9">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="75"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8095054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="378" mass="41429" checksum="9DF7C38279C70272" modified="2025-10-08" version="1">MSDFEDEMDVDAPPSKEIMFSSDNTTKGKRSAANLPVEAEDSLPWVEKYRPETLDDVSGHQDILATINKFVDSNRLPHLLLYGPPGTGKTSTILALARRIYGEQNVRQMVLELNASDDRGIDVVREQIKTFASTKQIFTMGGGALGRAADAMTNTAQMALRRIMEKYTANTRFCIIANYTHKLSPALLSRCTRFRFSPLKENDIRVLVDKVIVEENVKISADATDALVRLSKGDMRRALNVLQACQASSTPLRLKDEPKPQEKDIVRENITTESIYNCIAAPPPEAIEKIVQTLLNTSDVTSCLSTINTLKVANGLALADIITALAETLSTLEVKPEAMIRWLDGLAEIEYRVSGGGSEAIQTGAVVGVIREGCELTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ16</accession>
    <name>A0ABR1UQ16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660434.1">
        <property type="nucleotide sequence ID" value="XM_066819549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052609"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41390">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41390:SF1">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 213 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="228" mass="23862" checksum="8DAE869C5F0865E9" modified="2025-10-08" version="1">MPTRAELFEIGTKSLQTGALTGVLGAAFGAGSGIMRAAPPGLFALVAGIQWFALGSSFMASRSLLWHAWGGEEYLTAADKVKAGAAAGGVSGMIGGMARGPRNILPGILFFSTLAGGTTYVSQKLQSQEPKEKKSIMASKWSPMRQISDQEYEKILEDKVLRIDAELAILNDNIASLKGESSPSGSIRPEAGGSKPAAEAGKAVPPAPATQNTEKARPRWFSWGGRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ99</accession>
    <name>A0ABR1UQ99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_015314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660513.1">
        <property type="nucleotide sequence ID" value="XM_066819628.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052688"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8061093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="214" mass="23344" checksum="DBEDFA69AE8FAF9C" modified="2025-10-08" version="1">MFSVYIIPAVTVPSAPSYGTTPFEASGQPGQDACESPSLYCPFIVGEDPKPYSALVCTKGFTTTSGGYSEIRSQMEQCRPPSFFKVFETDANKDIITLAYPGTACLQDWTTACTYDITVAASDDADRQVTTSRQAWCCAPGYQCTTASVSSGTSATFERQCYSFLNTQTAVWASWDPPATGSKDGSEYYTYPTSITWDPPRDKYTVYHKPLPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQB5</accession>
    <name>A0ABR1UQB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660529.1">
        <property type="nucleotide sequence ID" value="XM_066819644.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052704"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF24">
        <property type="entry name" value="NUCLEOTIDE-DISULPHIDE OXIDOREDUCTASE AMID-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="16"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="437" mass="47355" checksum="8C7226B6A2A59677" modified="2025-10-08" version="1">MMDSHNQGARSTANPFKVLIAGGCYSGLAAAINLLDKCDSALDARIPVHITIVDERSGFCTPRHRLPLALSDKGYADKCWVDFADVKILQRPDVRFVHGRVQKVDPATRTATIRESASEADSTETYDYFIAATGLRRAWPIVPQSLTRKTYLLEAGRHIDAVRGSKHPVLVVGGGAVGIEMAAELKMMAPDVRVTLAHSRAKLLSAEPLPDDVKDRALELVREAGVEALMEHRLLSALPLKPEGELGHADSGYEVEFTNGHKMTASVVIEAISRSVPSTDYLPPAALDAESGLVNIRPTMQIKAAGGGGEEGVIPNADRHFAIGDLINWSGIKRCGAAMHEGRFAGLNIHQLMLQELSLASSSSSSPERDEKHVPEFQELAEIPPMIGLAVGKKGLSYGPDVGMKSGEDVLKLFFEDDLGFRIVWDYLRLGQDPVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTF9</accession>
    <name>A0ABR1UTF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660815.1">
        <property type="nucleotide sequence ID" value="XM_066818627.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051687"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046459710" evidence="2">
        <location>
            <begin position="24"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="753" mass="81013" checksum="D70DE762AE31ABE2" modified="2025-10-08" version="1">MRYSKRSASALAAMAALATPTSAASNNRPCSTITKGIDFVNECGIGYGGCHSVCSPTPIYTPPPCPGSTTSSSTPGSTTTSTASTTSTSKTVAPPPPTSSVSRPTSSSDVSSTQPSSPAPTSPAPTSTQTEGPTPTNAPGDPARPTSGGETPAKPTPDPQPTPPPSPGTPAPVPPPSQPGYGQVDGQRVPFGDAAWMQDGVNARRPPMDLADKAFQLPDAWAEKYGELPPLEFDTDLQVFHVELNIPKNPRPGFFPDQWALYIDEPFNPDRVIDILNQGPARLAPSIDTPWSGSPSIEQDMLWSAYQDLDVEIPQRSLQELRQLSDPITRDAWNALRRGELPGLPPTAFPFWPPTVAEYATLGGPALTAASLPWAHIGALLGIVGLIAGLAKGIPAAMNKKKKGARAPSLRVLRQLPGARDQHRQLQHRRAHPHHRPASGLGLPQRHPAAPRHLSPSEPEPADQRPRHHRHGHGHSYSPRPPRGRRPTLGDVLHHQVIPELQRFVTRPGTVSDSGLDPELEQNITQAVYLHASGIAHGIEEGGPNGKWFPDDLDMLNQLPRALYGQPLLLTVATSEEAVAQAAAQFRDGVGLEVWGAIGRMADHLVQKISAPLYPGKDQDDDGKDDPDAKKKQAPLTYTYMLGHHVVDKLTARVGDSLGETARVLGINQTRLLEARNQTLWDHVAPTYLAAAVSSHNHLVMYLRDVEVQKEMFNIEQLFRHGRSGPMLHYGLGIGKDLPTLQVPDKNAIKPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU24</accession>
    <name>A0ABR1UU24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycosyltransferase family 25 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014294</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660796.1">
        <property type="nucleotide sequence ID" value="XM_066818608.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051668"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050757">
        <property type="entry name" value="Collagen_mod_GT25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730:SF53">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730">
        <property type="entry name" value="PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="31531" checksum="EEB0D18CB499573C" modified="2025-10-08" version="1">MIEAFAKLGPTTEGIQKPGVGSAAAWLAHIDLLKYVIQSDLSSALIMEDDVDWDVNIKDQLSKAAETVRNHTGAPFEEQNPYSSNWDVLWLGHCGDIPRDNETFTFFQDPTVVRHSAYEGFAAGYLRDHFPEGQRAVYKSQGAICTYAYAVNRKGVRKVLEYVSGGQEQAFDTKLFHGCRSGALECISVNPELFRHFTPDEKFGQTSEVDKQNWGGEEKISKTAEGEKKGGAAAESSKYSVAKKITGTTKNIKESARCKALWDTTCTGRRESITDMIKNIAFGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV63</accession>
    <name>A0ABR1UV63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014882</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661384.1">
        <property type="nucleotide sequence ID" value="XM_066819196.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052256"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="37297" checksum="1173606C0775DB20" modified="2025-10-08" version="1">MKMDGREGSGGDESPPPLLKRGWVYQERLLSPRVLHFCRRELLFECRAGNQCQCGEREPEVGPKEIFAQLLTGDAALDSRQSHRGWWAMTRQYSQLRLTFEKDVLLALSGIAWRIGDTRPAEDDYLCGIWKSTLPYGLLWYVPDPNLESPAGSYPQRASDPRVPSWSWASIVGPIRWWLPSPHWNRNLVEVDHAQCTTDTGDGYGQVVGASLKLTGPILASELAWQPLVSRPPGDRKEPNNASTWHLPALSELANRPVDSEYSFHPDFALFTEQASPISVRCLWFKPDMALVLRPTDEGKFERIGLVHDWGGGELLTSQQLRQLLGTIKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWG8</accession>
    <name>A0ABR1UWG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LisH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014503</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661005.1">
        <property type="nucleotide sequence ID" value="XM_066818817.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051877"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610:SF12">
        <property type="entry name" value="SEQUENCE-SPECIFIC SINGLE-STRANDED DNA-BINDING PROTEIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610">
        <property type="entry name" value="SINGLE STRANDED DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="219"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="425"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="435"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="499" mass="53970" checksum="7140D733207AFB93" modified="2025-10-08" version="1">MNNVNMANMGAMGGPVGGAPIPMAMNNGNGALPAQPMQGNDRNHRCMLNTYIYDYFLKEGMVDCARSLLRTDQPLNVSKDSPGSRRDENGNALNGVSDDSMEIDHKHDVDSKDLPTPLIASSDTCFLYEWFGLFWDMHLAQRNRMGNNNAQVSQYINHTQTQNRLKQSQQQELLRSMRPDQAGGMPFNPMMRNMANGMQMPNNNLARKAMANNQNPQMMLQQQKQNQMQRDPSDMDGNRRPASPGSAENAPSPNKRPRLEGNTPFNPQQAAMMPNGRPQQGMPGQQQVSNTSAAQSHAQTAQLLIANNINPTSLTPQQFQNFQNQPPANQQKSIATYAQNMAGHHGNQMPNKGMGNPGVPQGQGSPMMTQPNGAELNTFYNAEGLAGGPMRPGAPGNAQGGGSNHALQDYQMQLMLLEQQNKKRLMMARQEQDSLGGGMPRGDGSAGPGGPGGPPGPNGQPFPDASPQGGRAGASPNPSEQMKRGTPPDEPCWYSVASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYN0</accession>
    <name>A0ABR1UYN0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014980</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661482.1">
        <property type="nucleotide sequence ID" value="XM_066819294.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052354"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13971">
        <property type="entry name" value="ADCK2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044095">
        <property type="entry name" value="ADCK2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052402">
        <property type="entry name" value="ADCK_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890:SF1">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2 (PREDICTED)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="213"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="305"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="696" mass="78827" checksum="2B9A6DB13EC224B7" modified="2025-10-08" version="1">MRTVHLLGRLCARRTTAQIAPKLPRCFSPRSQQSTLSAFKQFSSSSGARARSSHSTVLLAAVQGTLLGTAAFVKLSEKDNEPGDDDDQTSEGRMLEVSRDEIEKKKDDTSRGFTKFRHNLVYYVDVYLWEPICTGVRFLQLVAIFVPVIIAVPAIWVGARQPDHDNERSGTLWWYGFLVQAMEWSGPAFIKLGQWAASRTDIFPDEMCVIMSKLHSNAPAHPMRNTRRIIEAAFNGRPFEEIFEEFDEKPLGVGAIAQVYKAKLKPNLTAPADADVVENEAKIRQKVRKNVDTVLKSTPQRVPSTYVAIKVLHPRVERTVRRDLRIMSFFASALNMIPTIEWLSLPDEVVQFGEMMKLQLDLRIEAANLAKFRKNFKERSTAWFPYPYLDFTTRNVLIEEFAQGIPLADFLENGGGTFQKDIAQEGLDAFLRMLLLDNFVHADLHPGNIMVRFYKAQQPDLPKLQRHDEGHSKDQHDVTEEVLARLRPYRKRKDNTAWNAELKKIDTEGFRPQLIFIDTGLVTELNATNRRNFLDLFKAVAEFDGYKAGHLMCERCRQPDAVIDKEIFALKMQHLVLNVKSNTLALGNVKIGDILQEVLGMVRGHHVRLEGDFVNVVISILLLEGIGRNLDPDTDILSSSLPILRQLGARGGADMMKGGDFSMLMVWAGLEARRFMQASIEDVEKCVKYDLLSPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYS4</accession>
    <name>A0ABR1UYS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Homeobox domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_015071</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661573.1">
        <property type="nucleotide sequence ID" value="XM_066819385.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052445"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057939">
        <property type="entry name" value="TRF2_HOY1_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF5">
        <property type="entry name" value="HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24818">
        <property type="entry name" value="PH_TRF2_HOY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="70"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="72"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8062974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="617" mass="67902" checksum="14F270D1B8D61A03" modified="2025-10-08" version="1">MNTIKEEQHGIMAPTAMDQMQSDVTLTPASSTSPSDEHIKNSESPSPSASGKTPSSASRRPPRKSTLTQQQKNQKRQRATQDQLTTLEMEFSKNPTPTATVRERIADEINMTERSVQIWFQNRRAKIKLLAKKSLETGEDIDSIPESMRAYLAMQAMESGKGLGGAFLGRTGLIPYGSSMMLGGDQSGQGKVLIHHLTCRSLSIGKWTRVGQNTMDLIIFYSPEKCTMTYYINNDQAGYKIEYHFSHIKSITLDSNEGDANKLGGIVIELNRPPNFFMDSSPNSNGFFQCGDFTEDQQATQCYTHHLGGNPKVLSSQLAKLVSLESFMNRHNPNAFFDQGHSMGVASAPVSPTGNRPSSQPNFAQGHVGMFQESQWGISPPHPAMRGPGHKRQRSRSVPMPVDFSLFQNPMPSFYIQHPGETQGHPHNPNIFAPVPQQPQQQLSPVGPNLRIDTQAGFGMDLRPYPLSAATTAPSEYSSPNYFSQGPENTPLPTSNFNTPYSSTFLSPMVNPAMVPQSVSPLPFNHGDPAIVEQSPPMGMMRSASADLYPMGDSTVSDDGHSLNEMYSKHTINLPMHPHSPGFMDGSQGDLDMNQLVQFDSMDPSSMSPEHMPHQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3T7</accession>
    <name>A0ABR1V3T7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8064986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661740.1">
        <property type="nucleotide sequence ID" value="XM_066816048.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049108"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF2">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8064986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="367" mass="40721" checksum="11738706A5FDC507" modified="2025-10-08" version="1">MAQLPEYLLRGLGPLISTVRLPAVRECAERIAISDVEVLSSYNWVNPARPATIMVPGGPRVLRSPIRAVQLEKMETPGEAVEVLRPECRFDNVDLLTSRVVLMRLLKFCALGTGSFRLSASVIRNSLVLHISTRAQAELENDGIGTTGGASAGYGFSFEEAVTSYPKGLEDSHSHWRILRYNLGPLKCVLHYEADATTEPYDGGSRQAPVVIPAPDDLSATILLRGHLTPQEETLEIKSTGSTHVWAVSQLASKIWAGCTGHLLLGRHFDGQLEHVTMKKMQQESVKWCDMRRSQMALDRLPRLISELKQAVRAAPSRQATLILHEWPRLQVEVYDARHREPLVSPRMAKKFWGRRPKGAKPGTNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3V6</accession>
    <name>A0ABR1V3V6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GPI-anchored wall transfer protein</fullName>
            <ecNumber evidence="9">2.3.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_012622</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">A acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Endoplasmic reticulum membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the PIGW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662628.1">
        <property type="nucleotide sequence ID" value="XM_066816936.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049996"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009447">
        <property type="entry name" value="PIGW/GWT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06423">
        <property type="entry name" value="GWT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017321">
        <property type="entry name" value="GWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 9" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU280819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8065875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="479" mass="52023" checksum="C84DFAB97FAA95BC" modified="2025-10-08" version="1">MASNPSNSTSYKQLKEDFVSNLSGGEASEVNYVTAVSFVAILLWSVLQTRQSFFKSYGPLALLVDFLLSVCAFLLAITIYADKPFLLSGLLIAPAILIYALPTNIAAPKRKPKLPPNAQSKNKNAKDAGVASGRGELSVLSVKPFLTHYRGSLMIMTCLAILAVDFRLFPRRFAKVETWGTSLMDGGVGSFVFSAGVVGARPLLKERATGRTTPLARRLLDSMRHSLPLLVLGVIRLLSVKGLDYAEHVSDYAALSVLLGVIYQMVLESTDLKAYILLAPRTDLLSKNREGICSFIGYLAIFLAGQDAGMYMLPRKISASRASTPGAQRNSLLLRMTVWTGVWAALYYFVTNPVRGAGLDVSRRLANLPYILWVAATNNVTILAYYAIDAFCFPAFYNANDARTEREAYLTATSRVLRAYNRNGLAVFLVANLLTGLVNLTVPTLHVGPVATMGILLGYAATVTGIALGLDWLDVSIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3Z9</accession>
    <name>A0ABR1V3Z9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012635</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662641.1">
        <property type="nucleotide sequence ID" value="XM_066816949.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050009"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="59"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="474"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="477"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="495" mass="55616" checksum="5E8681C6408928B2" modified="2025-10-08" version="1">MDSTGIIQKVDSNEGHSEAEVTVSPAKVPLRKRLWSVVWDSLDKTPEERKFIAKIDWWILSYCCVSYFFKYLDQTNISNAYVSGMKEDLVLTGNDLNFLTTFWNIGYIIGQLPSQLILTKVRPSIWLPSLELMWSLIVMGMAGAKNVETLYALRFLTGLLEASAYPGIMTLLGNFYTPSELGKRSCIFQASSSAAQMFSGYLQAALFSGMNGKHGVAAWRWLFIFDGIIGVPVALYGYFAVPDSPTTSRAFWLKPKERDMAIARMECVGRKPMKKLTWKVIREIVTSWPVYLFCAIFIVHVLGIRIYSYMNLWLKATKLYTTEEINIIPTAGYGLQIFFTLSYAWTSDALGLRWPVIISACVVALIGTIILSVYPEHNLAAMMTGWLLTFCETGAGALIITWINEICSHSAEHRAIIIGVVETAAFTFQAWVPLLIYNTGEAPRFRIGYQMASAFFVLEIVFTLVILYCSKKWPQGGKEEPPREQVADGDTAHVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4H2</accession>
    <name>A0ABR1V4H2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662565.1">
        <property type="nucleotide sequence ID" value="XM_066816873.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049933"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="64" mass="6591" checksum="6B646A2D4C350B05" modified="2025-10-08" version="1">MACMKFAQEQLFVRCIDGAEPPGSNLQQGSGDPVVNLVVAGMFAGGSEAAKDSAISMTKALICQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5E4</accession>
    <name>A0ABR1V5E4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dimethylaniline monooxygenase (N-oxide forming)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663174.1">
        <property type="nucleotide sequence ID" value="XM_066817482.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050542"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="23695" checksum="0B08547CAA35E918" modified="2025-10-08" version="1">MADVQVNGTLKIPQSNRFEPDSFNVVPAEFPRGDFPASVDADRIANEFIEHFNKYLESQDYQALADLFVEDGHWRDHLGLSWDLRGLQGKDKIRKYLAANGKNLRQVTIDKSAPHFCPAIAPIDAYGKSRCIAFALKIVTRAGTGQGYVRLIPQDGSWKAYAVYTALRELNGFEPPWGQNRPKGDENRAAAAPTTGKKPAKRNPASRTRNPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5K9</accession>
    <name>A0ABR1V5K9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662037.1">
        <property type="nucleotide sequence ID" value="XM_066816345.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049405"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="586"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="613" mass="65207" checksum="7AED53AAF8A48739" modified="2025-10-08" version="1">MPLHLLGRLQRRLLEGQALLQQLPVLLAALLHHLVVRLLVLDGEPRLLDVVGARVGRGGDPPALVHLPDLLAPLGRQRGEHLGAVRVGLEDAAVGIAVEGLRPRARLLLHVDGGCAGKGVAEIRLDATIDRGRHAVELPGGLHVPVGAKRLRHRLVHLFLGVVGGVLVIVLVVKRRGVWHLDLPVEEAAVVVAGVVAGAVERAGLTVAFLAVALGPLLHVLLGEVAVVAQLVAAGAVAEGPRIGAAVEPRPQVRVREGAVGCSGGLLVLALEAGSHSRGAEREKRMGTRAGEAGAEGVAVVNVVEAEAPQEVGKVLLALAAGSGEVLPDTLVDVLGTLLLLGTIIITTYRPLPPFPLFGDDRQTAIRGPSTVLIRHFNPKPNVSLRTLRNLAPLPLRTHVGAVIERARDLLNPRRLIGCRLAVVLVTADAAAVATDAAEVVGSLAQHLDAVALDLDLIALAAAVVPDRLKEERDGVVNAHPAAAAPLLLLVLRLRRRLLLAPGVQLLGCQLLLGGLAELRFRGRELALLADLLAETLAPLFPFFGLVDLSLSRQLFVCLGLFGLKLFDLLYFAWPRLLLLNLLWLVLLWLVLLWLVLLWLNLLYFDLLCFILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V653</accession>
    <name>A0ABR1V653_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662277.1">
        <property type="nucleotide sequence ID" value="XM_066816585.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049645"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF82">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="51"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="597" mass="66780" checksum="7A64CF1A04C904A8" modified="2025-10-08" version="1">MQALYLSDVYEPLDSSKDEIRLLRILPSASHTAPLELQLDVVSLKSGGSNFQALSYTWETPSESGFRGITLCGRPHSVTANLHAALRRLRQKTTSRVMWIDAICINQDDLEERAIQVTLMKEVYSKAREALIWLGDSISPAQRSEHQASEDSSTAEQLSHRFLVEDAEPLSSLVERADALARSSSEDDALSAFAMLYLLSIDEHWCHKPMFHVGADLRYRLAPGYETSWRSLLKLFQMPWWTRVWVQQEFALARGAQFVVGNVMVPASLANNFYKSYAKHLLPGSCCHESVTWRMTSELWDDIAQKRLALWGSSAVRMMHLSGTQGNAKKNPGTALRELLWLLRTKDSTDPRDKVYGVLGLLSEVSLTEQTLLKPDYSLTASQTFARCTQYLIETEGDLMALVGPRTRRSDLPSWVPDLVPQDRRGALVSFQNISKRISTPLRPGPRSGSAEPCGASRSRDTIVGASNRRASARDWICWNILSVWLGEQDPSKRSVMAASHPDFATISKSFLVAMQFQSFFVTDDVHMGLGYETQPGDEVWILAGGKVPFILRPVADGHDQEARYTLVGDCFVEGIMDGERADEASWDTSAERIVIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V727</accession>
    <name>A0ABR1V727_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013722</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663728.1">
        <property type="nucleotide sequence ID" value="XM_066818036.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051096"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018515">
        <property type="entry name" value="Tuberin-type_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027107">
        <property type="entry name" value="Tuberin/Ral-act_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024584">
        <property type="entry name" value="Tuberin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063:SF0">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11864">
        <property type="entry name" value="DUF3384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03542">
        <property type="entry name" value="Tuberin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="3">
        <location>
            <begin position="1270"/>
            <end position="1505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="653"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="767"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1557"/>
            <end position="1587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1598" mass="176643" checksum="D00E856D28D1BB31" modified="2025-10-08" version="1">MLRRLVSLGQEAGEGQAKDDNMPQPAPGDDTSSSQESKINTGTIASVFKGLAGAAKLTKSPPAPLTTTGSIARAHITEQLHDSASHGLPQHHLEAFELLKNGNTAERVAAANQLRYAVEDYPLNPVLNIWYAAKDLIDPNNASTTRSAVWALLTACVKHPASTDLERKEYFQTITAPANPDDFHLQLAALVDLTKRGRSLSGFEYDIFPIVTNWLGAKFASVRAARKQASRFKGKAAAVGEDKDFADIFALTTDLIKFNSGVLDKNATQCLLETLVNICMTTGNTDDLRACIGVMDAIVTFGAIPDVKLKDFVQVLCSIHSMVPMLQKGAWHTLSMLCRSHNGHAVVRLLLGALSDLPMDQEKGGSDKQKIVIREVRGSLSVLNKLVSKSSEKGYPAVPFTTLLDGLSAVLKVTTAWKVQLDIIRLANTLLGTPQTKVNPMIVDEDWVSLLDIVATCLEGVTRTVPGLKEPIKPPATDSMVPSDTAIVSDEVGRLISRIEQLLTEQSGSLLQRQDCILFLARIHVVLPDSAAILVLNYFKEFRCCFPSDMQWETNLRLVLEALFANRHRSSQLRVMAVQAITEVYEMIELIHDQLDQDFVPNLMKSLLAGVTEEIDIEVLQEIVTFTTAIASNADYPLFDHIIEKLQTVLQTPSHPSSTAPGVLQTPAPPSSPDLSRTGQSLSDVVTLQKTQRLFDILISVAKSNSAEVDARISAMKLLFRLRADWANRIFVTEHTDTAHVAAILYRTEASLNRKMAEEAAHLTRISRSDAGGLGRTPRGRSFTQGQDKPLSSLASIRSGNSAQAAAARYQQSWSASETDVLPEQTSRIASSVVYSYAPECEPDGDSISISNATLPMGDWLATVVALLQQFCDWEIYSFILVYLPSQLSNHSIFKSAVPQIQELRRLLCEQIKTTGFLEPHTSTGLRRSDVATCLFHTLTMILSYHKHFQKTEEDEIVGTFTRGIGHWDRSTKVCLHALSICCYELPMSTSKALVTILQKMSQIVTQSSNAIHILEFLACLARLPSLYSNFRQDEYRIVFGICFRYLQYVREKKASQRMSTASDPSAQGLSSASGDSLIHPNASDDLPQYVYALAYHVITFWFLALKLPDRAKEVSFISKNLFTDHDGNQVSEEQAQITIDFMQRAAYADVDESMPDPYFTVERFGEILKRRWLIGNSIVTIEQATGAGYAQITKRQPSGTSSYMIHESFKAPPSHQERIANDIKGDGTQAQGNTVLPSHLLVHLFSTLPLADQARPIPLPQDDAVDRAMRTFDRSPTVDGHKVGVIYIGEGQTKETDILANVSGSSEYLEFLNGLGTLTRLKDATTNMQGLDRQYDTDGEYTFCWRDRVSEIVFHVTTQMPTNLEHDPQCISKKRHIGNDFVNIVFNDSGLPFRFDTFPSQFNYVNIVITPESRASFVATRQRTPIDVKESFYQVQVMSKPGFPEVSPAADMKIVSLRALPDFIRLLALNASVFSMVWSSRDVGEYISPWRNRLREIARLRERFGPKYGMAPSPPGTSLGVPNSGAGQLDANKAASTVRDSFSSLRRSSVATFFSTNSEQNSHSHRSSMLSTTPTENTEINQGTDSLVDTVDFSKWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7G6</accession>
    <name>A0ABR1V7G6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662681.1">
        <property type="nucleotide sequence ID" value="XM_066816989.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050049"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18436">
        <property type="entry name" value="BRCT_BRC1_like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18437">
        <property type="entry name" value="BRCT_BRC1_like_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18438">
        <property type="entry name" value="BRCT_BRC1_like_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17743">
        <property type="entry name" value="BRCT_BRC1_like_rpt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18439">
        <property type="entry name" value="BRCT_BRC1_like_rpt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053036">
        <property type="entry name" value="CellCycle_DNARepair_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47667">
        <property type="entry name" value="REGULATOR OF TY1 TRANSPOSITION PROTEIN 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47667:SF1">
        <property type="entry name" value="REGULATOR OF TY1 TRANSPOSITION PROTEIN 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16770">
        <property type="entry name" value="RTT107_BRCT_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="94"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="331"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="630"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="736"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="855" mass="94862" checksum="B3F664183F3630AA" modified="2025-10-08" version="1">MADQDGEKAPKLFDLCVFTFVESKELSATLIQELAQNVTKYGAEVSEPKRDGSLPLAAATHIISNTINFPQYTEATSMMIPVIKSTPTKASLPDPRMVFSDVVLSCADIPESDKESIIGASMAMGGTESSNLTKLVTHICALSMDHPKCQMAREKGLKCKIVLPHWFDDCFKLGKRIDDAPYLLPDPDILRAHPGGNIPIPSSQHLQGATSARPDFIPIPANSEAEARPKLTIFHEKNIMLSSDLSISTRLKDIVKELISDGGGELTDHVDDCDWFICHYRDGDDYVQAAHAGKHIGNLSWLYHLITHNAWTTPTHRLLHYPIPRNGIPGFKDLRIAVSNYGGEARIYLENLITACGATYTKTMKADNTHLITARSNSEKCDAARDWNISMANHLWIEESYARCDMQSLTVSKYTHFPQRTNLGEVIGQTMFDVDKLQALYYPGGRPKKPSSASKRKRKTLDVAEDDADADGSADAARRHTRKDFDVMQDDEMIADQSVQESGGPRPAKRRATSFATPAREQRHVRAGKENETPSTVSSSSRSAKDKARSRLSGLVDDIALYEKEKKRIPKDGQPWGGKRAADLIEKNHLNRRSASSPASASDQEEEVAAATKRASKKSKPALKQIEARVILTGFKRWVNDKHKEDADRRKLREMGISVVSDGNVCDYLVAPQLVRTVKFLRNLSRGATVVSSSWIETCLDTGEVPPPTDYLLKDKENEQKMGLKLQTSVARAAANKGRLLRGLPIYCTASIKNGTESYKVIAEANGAQFLVYGPRSGTTIKPTSPDEDPEGPDPVYLLSTANPEEKKLWKKFEDMARQGNMEPRVVASDWLLDVVMKQELSFDKKYLVTNFFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7U1</accession>
    <name>A0ABR1V7U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663088.1">
        <property type="nucleotide sequence ID" value="XM_066817396.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050456"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="214" mass="25405" checksum="E5C080646CDA6F39" modified="2025-10-08" version="1">MCIKHYVGYHCGHRDPEGTVMKPEYCRRPYRYDHEPTCDNSTFKVHVHVDLNRPRDSDFCPACREVRGEVWKEWAETYARWNQEHIVPVREQNDTHKRIENIFKYVELKSKQAAFRQGPDHTAQEQYRVFQNEILAPMEAQARRIRFANYAWNTRIAMAKQEGQVSEGFLDDLETLRQRNFGVTRMAPPSVSLFLEIQAQLFDRLKVEEDKANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7X3</accession>
    <name>A0ABR1V7X3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663164.1">
        <property type="nucleotide sequence ID" value="XM_066817472.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050532"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="74"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="318"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="544" mass="60378" checksum="441BF9F5EE9E12CF" modified="2025-10-08" version="1">MVRRSSLGAATTPSKRRRCSTPTRARSHEDDVDELANTPASNEIRFVSLRQVLDDRVKRRIRRHGLSEEMNVIQSEKRQRVSQDKAELERLRSELAEKDDEIERLRDVTFLQDTSRIHQLEQQVQELPGELGNRSSTLADQTQYDWTIAAQDPFSDSYMGDDGDGFGDTTMGELFVQACLPDPEKEALEAELGSLRLELTKLTDALESHETLKSRISGKLAVAQTAPDSELQPDLEAHLDGVLQSLADRTVALQDLNASLGALGFRGGDAGEIVASLASAFRSARLELEYLTPGEITLPLSSRGAEVLDLVLTKLRGLARKTREHEDAIDEYHELELSLHQQLGARRRPAPRKDARIEELDVSVDRLRGAIDDYRRDVGELEALVQRMETDADEARTAALDDMEQQFQQQKAETAGRHGAAVRELEIRLAAVASQTGALRTQLADVQARRATETAELNRAHGRGLALRDARVAELRGEIDGINEALRGAHETIRQLRVENATLASGLESEKRAAREAVERVLAETTPKAPPAELEGEGCLDPWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8R7</accession>
    <name>A0ABR1V8R7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663449.1">
        <property type="nucleotide sequence ID" value="XM_066817757.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050817"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="215" mass="23704" checksum="2368BA06EE9E6899" modified="2025-10-08" version="1">MAQRTGPTQFQLHVEGVANHQAHIYGTLFLSIALLVPDESLSWDERCELGIKTVQDVTRPATYAEKKAEFMKTGAGLLALFSGGGADAVRVHEPLAPTAESQMEGQLHNWVMTAPDPEVRGGTLVLCQAVFAADEEPDFYVSAHGSMNNDAAEALIPAFEDFARKTFQPKGPVRGAMMLLQASGDWKCIYWDGKRWLNLIFLEWQTAESMGFIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9G3</accession>
    <name>A0ABR1V9G3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663447.1">
        <property type="nucleotide sequence ID" value="XM_066817755.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050815"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="185" mass="20550" checksum="7AFD4B43C06E8A1B" modified="2025-10-08" version="1">MTQLGAAPNPIWGRLETWYAENGNLAMLQHYQVRFAEAEWSARMGSGGRMPRGSPAYTMAQDSSPLNHACQNGYEDVADYLLGRRATAAATAVRPVPGRGARRQPAHHGHADRLRDLVKGVRGRRLLAEAMLGEHWAMVELLVREGFVFTDSHRRFAIDKASKSGLDSMVDYLQSWETTVLSDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9I0</accession>
    <name>A0ABR1V9I0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663371.1">
        <property type="nucleotide sequence ID" value="XM_066817679.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050739"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11395">
        <property type="entry name" value="bHLHzip_SREBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF4">
        <property type="entry name" value="BHLH TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="145"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="275" mass="28986" checksum="3BACDE2C7E4B5FCC" modified="2025-10-08" version="1">MHGGRASYDFPQSSVPHLDFEADSNTLGTPLTPEDPCGSVSPDDYDFSSSLQFLDFEPNSRDITMDYYTTNTPKQVSPSPLLADSITVAPPPPPPLPQPTSPPLSPQPQSSASDKPSKKRPRVNSASSPHPAASRSPSPQGEAQKPQRPHAAVEKRYRVSLNDKIEALRVCLESRKRPKRQCQSAGDSPAAGSGGGGGGTTDGVAAPGGSGGATPASSAPAMRMSKAEVLTEAVEYVQQLEEENGVMLGQIQALIERMQATQRALQLPSFTAGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHN6</accession>
    <name>A0ABR1VHN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664558.1">
        <property type="nucleotide sequence ID" value="XM_066815268.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048328"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="393" mass="41743" checksum="031FE2C3D963E540" modified="2025-10-08" version="1">MASSQHVSELLRSLKKLFDSGVYTDLKIVCGNDQHQVHKAIVCLRSGRLAQLCSEIGLNQEATITIPDDDPQTIDLMLQYLYTLEYSPRIVAPTAAVSKPLANGINGVNGYHYKDDATPSPKTPTTNGGLATGVANGTQQQQQHPQPPTQTTLEYNIEREAFEAVPATAESASKPSKKAAKKKKRSGTVTADALEAVSPTPTAAPTAAPTVAPAAIPKEPLTPPPPPQHSLLQHAKLYTLARKYGIPGLRALSAARFAAEAEEYWSSDDFLAAAVEAYNATNPTAPTSATTTPNPLTAKQTAGIVAAVAASEEDDGHETEDDKPKTIRDVVLGSMKAHPELLDRAAVREAIRVNAELSFDLMMFFRDNQQQLGGGGGGSASSVVSMQSGGRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI35</accession>
    <name>A0ABR1VI35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal RNA-processing protein 43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_011106</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664711.1">
        <property type="nucleotide sequence ID" value="XM_066815421.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048481"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF9">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="12">
        <location>
            <begin position="47"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="13">
        <location>
            <begin position="261"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8070903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="358" mass="39012" checksum="71C2ABD6674D9EDF" modified="2025-10-08" version="1">MATPKSLTLSSTTFAKLSPHPYLLANLQPADPSTTPTRTNGRQPAQTRTPYINTSSLSHAHGSAVVRNGDTTVICGVRGETILTSAIPNYRAPSPADDSGSPLDEARDYDLLVPNIELATGCAPNFLPGVPPTTLAQTLSTRVYSLLHSSKLVDVSRLRIYPEEVGGEKNKEDNDEKMDEAEEEVDEYDVAEDKAVKAYWVLYIDVLFISFDGNPFDTAWTAILAALRDTKLPLAYWDADREMVLCKRSQQNATPLNLRGLPVACTASVFTAKEKQKKGSGSYWVLVDPDRLEEGLCDETVTVVVDKLGGSTKILGISKHGGTVVGPEFMKKMVATAESRWDQIHAARVEADADEIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI56</accession>
    <name>A0ABR1VI56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal protein S35- mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664635.1">
        <property type="nucleotide sequence ID" value="XM_066815345.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048405"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021036">
        <property type="entry name" value="Ribosomal_mS45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S35, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12298">
        <property type="entry name" value="Bot1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="247"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="329" mass="37054" checksum="19D86B398766FA1D" modified="2025-10-08" version="1">MPPRIPTKSSASSASALVRSSFVSPCTSQCLPSCRAGFSTTPSRERSTNLRRAFLQWTRTIGANYRQPKPEGGPNYLQSFGVGPNKPFPLNPQFRSERVLDEQARELIWEKVMRRGETLKAVSAELGVDLTRVAAVVRLKEVEKDWISKGKKLATPYSKAVLGMLPTKSFRPGVQNQPLEPINELHIHTATQKQLFWPTAESRQFTREDAAKAFHAKMLSADKRVPHPELIQMEKDLLKGMSPDEARARFINAAEQSERKAAEKQQKKAMAEEQATKKVNTPRFEFRFKEVDSELIGKDGRAPNVVGWKYGMPHYDRKKGLVKIPTSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VID3</accession>
    <name>A0ABR1VID3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA recognition domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011168</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664773.1">
        <property type="nucleotide sequence ID" value="XM_066815483.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048543"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12245">
        <property type="entry name" value="RRM_scw1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="302"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="478"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="478"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8070965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="501" mass="53743" checksum="42157E013B692988" modified="2025-10-08" version="1">MNAFDNDASIKPVGTPYATTPAPVSQVLIRRLPLDTTEEKLRLMVVFSQELVDVDMLSPEQSEDAGFRSAVLKFKTLAGAQQAKDMLHGKSISNDAEMIQQQPCFCHFKYRIFDNFIWPDFAPTIALCQWVPTGHGEDVAPMNGMNGMYASNELPNPESGTHYQSLFSPQSPIGNHLTERARISGKTLISHDNAEDDETQELLKNPVAYAENGATQGRRATAPHLPISRMANLSLNTSTSSANSLPPYGPSTMTPISGHSNAMSPTVMNSASHSLNYQVGSQHFHRHNFPPVNPADQNPPCNTLYVGNLPIDTSEEELKAMFSKQRGYKRLCFRTKQNGPMCFVEFEDVSFATKALHELYGHPLHNSVKGGIRLSFSKNPLGVRSGQTPGPSGAAAMAGINNMMAGSGAGFATTNGPPPGLSAPPGLNRMAYNGASSSSLSNGASAPYSSPNYPNNNSSSSNNYSGWNSAPYNNGPLSAGGSSTMLNASTSFPPPPHMMGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIR9</accession>
    <name>A0ABR1VIR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">U3 small nucleolar RNA-associated protein 25</fullName>
            <shortName evidence="10">U3 snoRNA-associated protein 25</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_011335</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
            <location evidence="2 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the UTP25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664940.1">
        <property type="nucleotide sequence ID" value="XM_066815650.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048710"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010678">
        <property type="entry name" value="UTP25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053939">
        <property type="entry name" value="UTP25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053940">
        <property type="entry name" value="UTP25_NTPase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933">
        <property type="entry name" value="ORF PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06862">
        <property type="entry name" value="Utp25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22916">
        <property type="entry name" value="UTP25_NTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7 10" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP25 NTP hydrolase-like" evidence="13">
        <location>
            <begin position="252"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="UTP25 C-terminal" evidence="12">
        <location>
            <begin position="521"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="116"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8071132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="701" mass="80318" checksum="18475CE5D8A98B28" modified="2025-10-08" version="1">MPPKGRQGAMRGGSRPRGRGGKANVQKRVHGPRFNKARLAEVQDPEDEESGEDSPSDEDVEEEDDSEDEEEQAAHNKSYMALMSSFAKQSAPNNKRRKPSQQNSDERPSKRQATEPESEEETEDKDVDVVEEEPEEGPEAEMTLDDEDDDEDEVPDASDPFETHFSIPDEAQVSKRIKAVKANEYSVTQAELNGWRLTRSVPGKAPGDSEKPLSLMPDTSSLKLKQKLRETAAKKPTLDKLEQVLYPITFGYNDLLFCNRTPKNGGKLRRMACLHAVNHIFKTRDRVIKNNYKLSKEGNATDFEPKDQGFTRPKVLMLLPTRQSAVNMVKEICAICEPDQQENRKRFDDTYVDKDSKFSSDRPEDFRDLFEGNDDDMFRLGVKFTRKTIKYFSQFYSSDILITSPLGLRLAIGSEEGKDKKVDYDYLSSIEMVIVDQADALLNQNWEHVEFIFEHLNLQPREAHDCDFSRVREWYLEKQAQNYRQSLIFSAFNTPELQELHRQCQNWAGRVRVQPEYPGTIQELGVKVKQTFSRFDASSVAAEPDARFEYFISAIVPTLAKRAKDVDGTLIYVPSYLDFVRVRNYFATSPAAASLTFGTISEYADMPEASRARSHFLNGRHKVLLYTERAHHFRRYMLTGVRREIVGGYLAKSEQEFKLEPGQGTVRVMFSKYDVLKLERIVGSKRVGKMIRERGDTFDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ28</accession>
    <name>A0ABR1VJ28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011449</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665054.1">
        <property type="nucleotide sequence ID" value="XM_066815764.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048824"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF37">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="75"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="483"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8071246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="510" mass="57221" checksum="32668CE086A8D937" modified="2025-10-08" version="1">MDSHETGKPGTRPDASKGYSQDPIAVKPTEDGSVRSEDSPPLKRGFWNTVRRHIWDDPDKPEHEKKFLLKLDAYLLSYTCLGYFCKNLDQANINNAYVSGMKEALHMEGSELTYASNVFTAGYVISQLPTVILVSKLRPSYVIPTLEVLWAIFTFTSAAVKTVPQLYAMRFLVGLCEGAFFPCIIYLIASWYKKDERAKRVTLFYSTASLSHMFSGYLQAGVYQNLDGALGHAGWQWLFIVCGVISLPVGVIGYFFNPDFPETTRAFYLTKDEAAYASRRLVEDGYKPLGAAAWDRKKLFKIVLSWQFWVLSLGYFFVQTSHPNGQPFMALWLKSEGESIERVNVLPTGQSAIGFVTQALIALQAGSVLACIILAVWDFPSKALKYFAMYIAYTSSGVPGIYYSWFPDLMPDDHEMRGFLTAFSNVFSYANNIWWTNWLWKTAYAPRFHAAFVATAVMGVVLVLTAFLMHFLQGRDAKIRADREAKEGEGANTRVPNGAESLDPNTHAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ32</accession>
    <name>A0ABR1VJ32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aconitate hydratase, mitochondrial</fullName>
            <shortName evidence="8">Aconitase</shortName>
            <ecNumber evidence="8">4.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_011431</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="8">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665036.1">
        <property type="nucleotide sequence ID" value="XM_066815746.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048806"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="entry name" value="Aconitase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006248">
        <property type="entry name" value="Aconitase_mito-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01340">
        <property type="entry name" value="aconitase_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005558">
        <property type="entry name" value="PRK07229.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF2">
        <property type="entry name" value="HOMOCITRATE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="10">
        <location>
            <begin position="71"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="11">
        <location>
            <begin position="576"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8071228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="776" mass="83609" checksum="A92A2F67B527D6B4" modified="2025-10-08" version="1">MRAVELACRRGTAFNHEPPHTPYFKLLKNYEKVREVLGRGTALTLAEKILYSHLDNVEESLTTNTNGGRNIRGTANLKLKPDRVAMQDASAQMALLQFMTCNLPSTAIPASIHCDHLIVGERGAKADLESGIKVNQEVFDFLESAAKKYGIEFWPPGAGIIHQSVLENYGAPGLMMLGTDSHTPNCGGLSTIAIGVGGADAVEALVGAPWELKAPRVLGVELKGQLSGWASPKDIILNLAGQLTVRGGTGFIVEYFGPGVESLSCTGMATVCNMGAEVGATTSIFPFSPAHVRYLEATHRHDVAAEAKKFSDIVKLRADDGAKYDEVITIDLSSLEPHINGPFTPDLSTPLSQFKETVQEQKWPEKLSAGLIGSCTNSSYEDMTRVESMVREALEAGLKPSSDFYITPGSDQIRETLARDGPLETFKEAGGTVLSNACGPCIGQWKRQDGVEKGTPNAILTSYNRNFRGRNDGNPDTMNFLASPEIVTAMSFAGSTTFNPVTDSIPTPSGKEFRFSPPSGSEIPTKPFESARPEFQAVVQPPNASVNIAISPSSERLALLEPFEPFPNSDLSGLRVLVKITGKCTTDTISAAGPWLKYKGHLPNISTNTLNTAINAETGEVNAAYDLDGSKHTIPELGQRWKEAQQPWLVVAEHNYGEGSAREHAALQPRYLGARIVLCKSFARIHETNLKKQGVVPLTFANEADYDKIGASDEVATEGLYDMLQNGGKGEVSLRVKKHKSGEEVVIKTKHAISEDQAQFILAGSALNLLSKSASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ56</accession>
    <name>A0ABR1VJ56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665075.1">
        <property type="nucleotide sequence ID" value="XM_066815785.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048845"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF16">
        <property type="entry name" value="ANKYRIN-1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="149"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="188"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="221"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="254"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="286"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="321"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8071267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="41401" checksum="25015B06E459C07C" modified="2025-10-08" version="1">MPCRADTRSTKKLHDAIAKCDYPAVYKYLADGADPNATLKGSTITPLHRALDLMDEMDGSGSDSEKPSKGAAFTILAQMDAMKGYHDRRDAKGVLSILTALIVSGSNLRVRDDFGRTPLMRAVKGDMGDSIVSLMLEYGGNLVNVQDNEQNTALHFAAMQRSSTKAKNLDLIRILVAHGAEPSVRNAKSRTPLYKAVMRGNLERATELLNYGADLEGTDHHGWSALHTAVLGGDAAMTTLLCHHGAGYDNRDRAGQTSLHYAVSKGHIDVIVALIEAGADVNLATKGETPLCRATAQGCLRVAKLLISRGANVSLPSARYFGAFPIHLAAMGDNRAVLELLLASGSPVDALDDRRRTPLQWAADAHKDATVEYLVTKGARRVYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJQ9</accession>
    <name>A0ABR1VJQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011689</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665294.1">
        <property type="nucleotide sequence ID" value="XM_066816004.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049064"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8071486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="72" mass="8353" checksum="4A8CAC7DBF77C025" modified="2025-10-08" version="1">MLLGPKDDSRLIPVDDVRLYEEVCGDVTRFIIRVFGEINVLKLCPLQMDRTYAIDWPIANWSTVRSQSKARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTF3</accession>
    <name>A0ABR1VTF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665484.1">
        <property type="nucleotide sequence ID" value="XM_066813522.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046582"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="543"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="641" mass="71683" checksum="0AE3D4B61B64B05D" modified="2025-10-08" version="1">MTIRVSAAVLDMPRSMMIPANPKSAPKPTDKHSWRMEVSTMVLCLSAVVTSTVLLIHADGRPLTDYNFFISFNTLISILAAVARATLAFAVGSCLGQWKWNWFSKRSDTLIVFGSFEDASRGPLGSFWLLCRLRARYVDERKPKSLTPLLMLVVPLSEAGRAFVTLLMLGFEPFMQALIYYQGRLVTTQPRTAPSIGVSNRLDIGSYKLVREQEAASFTFQNQSFLYIKGQFRSEASAGLASAVYRGFYANDPRDAVSFTCSTGNCTWPIFTSLSVCSSCNDVSDQVQVKEQDGKDLGTIHVNATHLEGHFITKALPYVELANPATVTYVDMVARRDIVSDEPISNAYMSAKLLNNQGNTLTFGKLNTMIMACALYFCTNAYKSEVSDGQLKEDIVASWSDRVVNSYSPQEPIRDNWNAYEDYTNHSLDNGHAAYRLSDLQLQIPRAEADRYKLPENVTLLFNITQSTIGSTLSFLQDFLREPLVYGESVSDSIVSKTLYDSANLSETFAGAARAMSIWIRDNSNLTTEGDQQEWVLHIRVRWPFVTLPVLVVFMGCGFVFLSMWETRRLQLPPWKTDMLATLAHYLDASTREQLRAAALQGRAREEAKGMVLNFEDTGKGLELKADAERSNRELDELQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUG3</accession>
    <name>A0ABR1VUG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_009558</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665835.1">
        <property type="nucleotide sequence ID" value="XM_066813873.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046933"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058545">
        <property type="entry name" value="Beta-prop_EMC1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026895">
        <property type="entry name" value="EMC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011678">
        <property type="entry name" value="EMC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25293">
        <property type="entry name" value="Beta-prop_EMC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07774">
        <property type="entry name" value="EMC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045240728" description="ER membrane protein complex subunit 1" evidence="12">
        <location>
            <begin position="21"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="919"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="domain" description="EMC1 first beta-propeller" evidence="14">
        <location>
            <begin position="20"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 1 C-terminal" evidence="13">
        <location>
            <begin position="715"/>
            <end position="948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8074895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="951" mass="103017" checksum="10E545FDE92FDE34" modified="2025-10-08" version="1">MHLPLSALSVLLALPAAVRAVFQDEVGHIDYHYELLGVPQRETTFFHRPRRQDKASLLYTLSDLGVLGAVNPSTSSVVWRQLLQGNITNGAGYLRAGEDATWVASAMGSSTQAWDAPTGRNLWSLDFDGRAKDLEIMELTESDHKDVLVLYEEEGATVARRIHGLQGHVVWEFRAVNGDIPLQVSTNVEKVFVISLHGSLLSYSLKVTVLDTLTGKRLDEINIGTKGEVQKAEDVMFVGANSAAPIVAWTDNALTKLKVNVLGNKNKQEFPLLADTRSIEIHAPHHIQSQPHFLVQSRTKTANKADVFHVDLKTNAVTKAYDLPLLDGESAFSTSTAGTNVYFTRVNPDEVIVTSSLSHGILGRWPLKGNDVKAGALHGVSEVIKKSETNYAVRSAIVTDTDDWAMIRNGEVAWTRPEGLTGAVAATWAEIPESEDLAKTLEAEAHSNPLEAYIHRVKRHVDDLQGGAKDSATLTRDSFGLNKLIVLATKRGKLYGLDAGNHGRIVWSKSASETPSTLPWDVKSIHADDVKGLITVRGADGEFIIVKSDTGKTVETMGPGLWPPVQSVAVVDSAAGPWLLPIGIDGKIGEVPLAYAPKQTVVVRAGNELKGITFQPQGEQAVEVPAWVFSPSGKQKIVHIATRSPHDPIASVGRVLGDRSVLYKYLNPNTLVVAGIDEASSTMTLYLLDSVSGEVLTSSTHQGVDPNKDISCAITENWFACSFFGQYAVRHSETQSVKGYQLAITDLYESEVSNDRGPLGEALGEDAKFSPLDPIEQPTGPVIPSAVSKTFMLSGPITSLAVTQTRQGITSRQLLAFASGSHSITGIPRMVIDPRRVVGRDPTPAELEEGLSKYTPLVELDPRFMITHERDVIGVKEIITAPANLESTSLVFAYGVDIFGTRMTPSLPFDILGKGFNKVTLIGTVLALTAGVMALGPMVRKKQINMRWYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUK9</accession>
    <name>A0ABR1VUK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665878.1">
        <property type="nucleotide sequence ID" value="XM_066813916.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046976"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="560" mass="59008" checksum="2E2BEFC1B7A7881D" modified="2025-10-08" version="1">MPFTSPTTEPFPQYDEYDYQNVSPQTFGFSSRAYEGASATSDTHMKKPHLLNPEAVEFVSPSRTSGTLTEANTPLNAGKGIAAPLKLAPVVQLPMAPAKSSGTSPAAIMPTSPAKPAATPTRQQHDTSKPNSLAPGMSDHKDNNKGREDGDEKDEQSDIKDFASFNKSRKSTAESVIPADETGQAEERKSPAKKQPLTKHKQNKKSKSQTSQGTHAAENGSGGQAQKESGKKTQSSSDDRPASHSSDKADKQKLGNNQNQKQGQSEQKGLVSKGSNAKGKSAAKEVPDNQPVVPGAIWVEGGEPKKATKKKNLKRHASKGKPVAKAAGSSVDAAPTLSKEPDCKGEQGSGSQATSRGSNSEHKAKVNRRGEAENQSGLEKAVVPAPKANSDAVATASTETAAEAKERETPANQSNECEQKTSKGSATEPHKEAEPSSSTQAKKGKGKKQKASAASQNVTTQDKDLTVPSVVAPAPDDTKVERRDTMASLSKADLPSILDDNDVAALSSSGTKTPDLRDAPAPDRSPWRKDGKNTASEKRNEEGASVVPETLREGEERKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV48</accession>
    <name>A0ABR1VV48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein EFR3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EFR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665997.1">
        <property type="nucleotide sequence ID" value="XM_066814035.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047095"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039786">
        <property type="entry name" value="EFR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049150">
        <property type="entry name" value="EFR3_HEAT-like_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766:SF1">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21072">
        <property type="entry name" value="EFR3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="589"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="833"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="922"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="594"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="833"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="888"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="999"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1012"/>
            <end position="1025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1080" mass="117848" checksum="C6A7344472325208" modified="2025-10-08" version="1">MNALHDKCRPKHQVLVLKCYPRTTKGAVDVKPNSSELSYLLFYATSRRSKIQKVGAFLEKKTASDVWRLRIGNVQVTLQIFAALIEKAPKDLPLFAQNVMKVLGNVLRSNDITMVEASLPTFQTFCEHQDASSLFADQTYVQQYEEIVQAYAAFASTKNTPGKATLSKPVVMRWRNAGLEAIKSVAEAEALVTVAGRQLDVIVPMILENLRTDNEEFLDVLIHRAHADEKVDPQPATRHRTSISTVQTNETSGEPNPIALSGSAADADKLAEEETGLAAMHCLKQICVVPNRAQLHSATMALLKFVRELVQADVSVVRANPTTGRHSGWAIEIFGLVARWAPVQDRYVILLATMDTLAHTPSTEENIPELTVLVAIMSSLLRSDVNLIGLSVMDVLLGLLGQVRKALKSSGRTTPGGTPKTPDKEADPEQDQHMTPQRKEYLARIQQCIGDLATHVYYADQITDMISAILVRLKPHPSTVTGSPPTEKPPDDQQSPDAFVYLERAKITALKAIKSILLVANPKTKVSGNVNLTRNKVPVQVWEGTHWLLRDPDGLVRKAYADALTTWLDRETTRADLIARDEAQKATRMGSKDSQSAAFARRAVSSASNRERPTKAPRSHFLQLLHLSIYDNALQFAAYETDMVLCHVLLVKLVTKLGVNAARFGVPMICRLQEEIQETEAPISKVHLGSLCHGYFWALTEMFDCETTEVGRAIQNEISRRRSKHFWIDGINVPAPLMDSLGTPGKVQPESKIPVEQIATEALLPFDDRLAMPYLAANQPGRFPGRTFNTPIFSSTLSAIPPAETDRVLPTKFREDMLAEWTKESAMMALQEGSKTTSLNGSKAATTATRGNRLQVNGQGSPVDSYNNLRPASHTGAGGSMAALRKTSVQSRGSGVSSSSRGIVASVDQLKSVLSGEVARPGTLHTVRDDDSSDSMVSYDYTPSELSFNPAASEGEGRSRSKSRERKTSDPNGTVSAHPTPENGREQSGYVPPVPPLPSSFTGAQTSPVTGHRPESAVSSKDHAVKAPRRRSVKSRGGESILTSALGDDGSGAMDLQSLLKGIDSKSREHTLGNLSKPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVW6</accession>
    <name>A0ABR1VVW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666330.1">
        <property type="nucleotide sequence ID" value="XM_066814368.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047428"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="52947" checksum="28653ED4D0C02098" modified="2025-10-08" version="1">MGSSDDDLNIENGCKPDLKRCQANFVTSDHARGEIEKGVFSGEKTQPITINRLFCLPEPILSNDESDSDDTQSWNDDFVEVSEAHISTWDAFNDENVDIMFWDFLDEKLQPIHNSNLMVAYGGSHHKSGIDDTREVFAIEEECHLNIMMESASIARVLEMAFAFTAKEFQERVNASSASGTLDTGYEANRIRITRSSFVRKSSETIPDWLFCLVSESASRERWHDLRWALRWAYEQNAVTGPDDDEPDGPDPDGGPTLANILSQFAGDGIDVPVVGEVKRKAVFNPANLADPDKFPQVRSTLGQMLMYCRWAKTRYAFVLTSEEVTCLRFFRLEDSKEEEQFGVHYAVLPWKREPGKVSVWKGIWALVMLSLHNKHRPIVPEDQIHDLNSWSRVTDNDQDQGRWENHLSKIVVDDGYWAERARAMDASSHESAAQPDRHEEGKATGQRPKRSTSGSVERPCKVIKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW22</accession>
    <name>A0ABR1VW22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Stress-response A/B barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665977.1">
        <property type="nucleotide sequence ID" value="XM_066814015.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047075"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="1">
        <location>
            <begin position="4"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="111" mass="12215" checksum="1935BACC7C97F511" modified="2025-10-08" version="1">MAPVHRVTMFKLPDTSAQQKLIEAYATLLKEQKKDGKPYILHMTAGEAMADPRSQGWTVVSKAEFASLEDMRYYDEQCEAHAALRNYAKGLGIQGGPAGVMTVYYEAGASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW54</accession>
    <name>A0ABR1VW54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_010127</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666404.1">
        <property type="nucleotide sequence ID" value="XM_066814442.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047502"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="15"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="966"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="7">
        <location>
            <begin position="966"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="7">
        <location>
            <begin position="1123"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="7">
        <location>
            <position position="998"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="7">
        <location>
            <position position="1188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2277" mass="247074" checksum="78DB76F2BD824A7E" modified="2025-10-08" version="1">MRTTSNRECHIGLGSEPVAIIGMSSKFAGDATNTDKLWRMLIEGRSGWTPFPSSRFNLDGVYHPNNERLNSTHVKGAHFLEEDVGLFDAAFFSYSSETSSSLDPQYRLQLESVYEALENAGLPLASIAGSNTSVFTGVFVHDYRDALLRSPDALPRLMATGTGVPMMSNRISHFFDLRGASMTIETACSSGMVAMHQAIQSLRTGEADMAIVGCANLTLNPDMFKALGSAGFLSGDGKSYAFDSRASGYGRGEGVSTVVVKLLKDALAAGDPIQAVIRESLLNQDGKTETITTPSLQAQEALIRGCYAKAGLDPRDTQYFEAHGTGTQAGDTIEAQAIASVFGSRTEPLLIGSIKTNIGHTEAASGLASIIKTALALKKGVIPPTINFEKPNPKLSLEDWNLSLVSETTRWPETPVRRASINNFGYGGTNAHIIMEDAASWTTGRMNTIQLNGYINGDAHTLVTNGSCSTVNGVESPDGDSSRVLVLSGKDEQACQTLVSRLGDFLEQELTMQEHQRQFLDSLVFTLGQRRTRFPWVAAHPVTGGIDAVVQGLRSPKFKPTRSSSAKPRIGMVFTGQGAQWYTMGRELVDTYPVYGESLREAEGYLKEFGATWSLVEELSRGAEVSRISEVALSTPICVAVQISLVRLLRAWGVVPTAVTSHSSGEIAAAYAAGALSYRKAMSIAYHRAALAANPAVRGPAKGGMIAVGLGQSDTEVYLKRLVSGKAIVACINSPSSTTVAGDMAAVVELEDLAKADGVFARRLKVDTAWHSHHMAPVASAYAEELEADNQPAEANTVFDEPVAFSSPVTGGRMASSQDIANPQHWIDSLLQPVQFVAAFTDMVLGDGGGSVTNVDVIVEVGPHTALGGPIQEILGLPEFEGLRLPYYGSLVRKSDARETMRALAANLLRHGCAVDLGAVNFPFGRGSHVEVLTSGLPTYPWNHKIRHWVEPRQNRALRQQSLPPHDLLGSLVEGCNPETPLWRHFLRISETPWTRDHMIQSNVVYPAAGYICLAIEAIRQARTLKTAAIAGEVTGYCLRDVEFMQALLIPDSSDGIEVQTTMRPVDDKAARAQGWTHFEVWTVTSDNEWTQHAKGSIMVEYDNSSFDRVDGSDVPRDIEGYARRFLPGDLFANLRTLGISHGPLFQNMTSIIQSGSERRSVVAMTVPDTLVPNDLPRDHLLHPVYLDSVITAPYSAMPEVAGRETAAKVPRAVESFWVSAKISNKEGHAFKASSSIIHDDDQDMKANVMVFDHEDGRPVLEMRTFSYQSLGRALSLQKREPWQDQWCNSVQWSLDVSIASPATFDFIKSQLSSNEVDLSEVSLTESIRRVCVGFMQKALRNLDPQDVQRLEPHHAKYYLWMKDVVEKAASGKLCDGSTEWLADDEVQNRRLINQVAHTRGDGEMVCHLGPHLAAILRGETTPLEVMTRQEGLLARYQTGTPKLQCAGSQLAGLLRHLTHKNPRSHILEVGAGYGTMTRYALDALGTTATGGPLASSYHFTDVSDRTFEVSREIFADWSDLLSFDLLDIERDPSAQGFSDGSYDLIIASHVLFGAKNADTLGNIRRLLKPGGAVLVVEDVHSRVDNDFVNGLLPGWQFGEEHMNYGQLCRPRWDESLRNAGFTGIDLELHDHDGTGDYTTVLLMSTAVPTEPAVPSPRLTDPENTVIVVSERAGAPPSAWLEKLRHSLSSRTQDGEERLPALQDLESDSATSAWYAGKTCIFVGEMDEPILYDLDATYLEGIRAMSTGCQGLLWVTRGGAVGCERPEMSLATGFVRTLRTEYVGRKFLTLDLNPQKPLWSEEGLSTIVQVMLQSELGKSSNSGAALGKGPVELEYAERDGVILIPRLYHDIRNDQMMSRSAHGSGDDGEVATQNENTVLACGDHEKAPVLPRRTAAELSANASYLIVGGSGGLGQSVAHWLVSHGARNLILMSRNAAKSQHTAALAEELRRAGCYRVLPVSCDVASQDDLARAIHMCAREGMPPIRGVIHAAFVLRDSFVESMTLDDYKFTTESKVAGAWNLHNQFNLPGDLDFFILFSSINGILGYPSQAAYSAAGAYEDALAHWRVKQCGLPAVSIDLSVVNGVGYVAEASAAEMLRKTLVRAGRRVIGEDHVLAALESAVLSPHDPQFVVGGINSGPGPHWDVDGDLGRDMRLLPLQYRKPSATDEQQQQQDGGNSLAARMAACGTREEAIGVVGSAMADMLADMFLVPVEEIDLAQSPAQQGVDSLVAVEVRNMLFSQAAAELSIFNVMQVTSLAILAAEVVDRSAHVNFDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWV8</accession>
    <name>A0ABR1VWV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Patatin-like phospholipase domain-containing protein</fullName>
            <ecNumber evidence="6">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010350</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Lipid hydrolase.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable lipid hydrolase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PLPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666627.1">
        <property type="nucleotide sequence ID" value="XM_066814665.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047725"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07230">
        <property type="entry name" value="Pat_TGL4-5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF10">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="8">
        <location>
            <begin position="220"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="673"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="5">
        <location>
            <begin position="224"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="5">
        <location>
            <begin position="251"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="673"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="734"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="797"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="841" mass="93341" checksum="9DDF6DBCB5CA92BE" modified="2025-10-08" version="1">MTDLLLPSLRLSSPSSRKNQSKGDAASNTICPQTTAVSATESLYKALRSLSSLALPYRDDISEAEREAQRKLDERKQILMVRLQNADTYSQWEAAAQELDILEGNEEWKADTSSGDYQPDLIESRLRDLDTARINCDLRGMLHLIRTALSRDLGGMGNIDLYRHSYYGTKKLIERYVDSTLQTIAAVVERSAHPLPGDLETKDLLDAVLFARQSFGRSALLLSGGGTFGMSHIGVLKSLFEVKLIPRIISGASAGSIVCAVVCTRTDDEIPQLLEEFPYGDLAVFEEEGNEDGLMDHVRRLLTQGNWSDIKHLTRVMQNLLGDMTFQEAYNRTRRICNICVSPASIYELPRLLNYVTAPNVMIWSAVAASCSVPLVFSAAPLLVKNPLTGEHSPWNPTPQMWIDGSVDNDLPMTRLAEMFNVNHFIVSQVNPHVVPFLAKEDAPYPISGSQDYVHYDDEGDWLSTMTQLAKGEALHRMHILAEIGIFPTLVSKLRSILSQKYSGDINILPAMGLLDLPRILKNPTISFMHRSCLLGERATWPKLARIRDRCAVELALDRAVHALRARVVFSKSQVDLRRMATGSLVNPFRGSETFHINLPAIETVTAKDKLRQRHRRSSGSCAQQPIVLPRRLEDPYKVTDDDTDVEEQLEMALRKPHGKSKLKLKRFSKNQAFQTGPLTTPHLSSTNEPNAFDFAQPPSPVKVNPQVPRDGTALGPGDTLSALKAFEVEDSPDPTTTTLDESSTVFSSRGPSHSTEMETSDPYTSDADIDSRSDDSALGPDIVRSPSETATDSDDPFLRRAESSHEESTPKENIFSRSRRESSSWNGIFDPVDPGAGLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX24</accession>
    <name>A0ABR1VX24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADH-ubiquinone oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_009112</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the complex I NDUFA8 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665389.1">
        <property type="nucleotide sequence ID" value="XM_066813427.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046487"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016680">
        <property type="entry name" value="NDUFA8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13344:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13344">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017016">
        <property type="entry name" value="NDUA8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CHCH" evidence="10">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR017016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8074449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="177" mass="19945" checksum="07F5E03AF8DAF3D1" modified="2025-10-08" version="1">MAARKPIFNQQVLVDTTPLPDSVPKVKEVGATSAPLLSASFFIGARCRPYNDDYMQCKTENPGKGELECLKEGRRVTRCAASVVDDINKHCLDEFRKHWQCLDNNNHQLWQCRKDEWKLNKCVFDNLKLEKTIPEAQGIPVHLRSKQIYAHYPALRDPGQAPFKKAVDAPGAEAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX37</accession>
    <name>A0ABR1VX37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_010425</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666702.1">
        <property type="nucleotide sequence ID" value="XM_066814740.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047800"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07199">
        <property type="entry name" value="Pat17_PNPLA8_PNPLA9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PNPLA" evidence="9">
        <location>
            <begin position="812"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1293"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1343"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="7">
        <location>
            <begin position="816"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="7">
        <location>
            <begin position="849"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="7">
        <location>
            <begin position="1011"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1293"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1371"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="851"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="1011"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1539" mass="172023" checksum="30C57769C6AFDF16" modified="2025-10-08" version="1">MNWTQSVPLQQRQGSGSAAAPQNSTPQRQASELTEADETPDIFEDAQERWVFEASRASSPLPEAPTMGMSPPEANYVQTKRRSRGSSSVEARPPPVPPKTAPQPIAAVPFQATVEEAFAPNAPSLSTAASETIYQKKCEQCEEHGKDNVLSPPTDNWVREQLYKADEITSWFGVERPEDNAPPVFQDYGRFADLMASTDPIRSQPSFMERWAEVDRDRRTPSLVSFVGQTGAGKSTLVKLLIDFGLNGPAFFPTPVVGPRGAHLPTSEDVHLYLDPRTCDSPGPLLYADCEGLEGGEREPLGAKFRRMRRAHKDNPNETEANAEAQARKASKIISERELEWASESRTRSREFAVTNLYPRLLYTFSDTIVFVLRNPRTIEHVFEKLVKWAAAAIETSSNQPVLPHAIIALNASEHDIDVKLWDVKFNTETILEDLAHTVNRNETFKKWAQFWRERGKAIDNLLDLVLCYYSTIQIIRLPADGRPKLMAEQVEKLYKATLSGCIAARGARNEVRMLLDVEDMHAYLQEAFNHYSKTLESPFDFVQASFRNSPIPPDFGGNILKLALGMTHLWKDHPQIQAPQIFSELSYMVASCIMLDSSRHKNKGFADQIFPKYMDHLEDALENFCDQHWPCEFVNPKTGVRCVNVRFGHTAKGHQSADGKVFATGEYQSKFSFENNAQEFRQKVYSCLTQLLQQLTTDYRFGTSEESAALAIHQNMVMRSFFRRATYNSSSNKSHAALTSHTACFCCLFGQAEHCLPCGHVLCTLCLQGYGEQHNVHGYRVFGCPMEEIEGGREEACTIYLKPASAGVRILTLDGGGIRGIVELEVLEQIEIALGGIPIQCFFDLVVGTSTGGLVALGLGSMQWRVSECIEKFVKLCDEVFTRRSGSTLPLIGSFIENYHHSKYQTTTLESAMQFAFTEDLLLYGGQRLPGTTLPLKVAVTATNLAGNKTYVLANYNQPRGAPKSSHYHFQRPEVNDTELKIWEAARATTAAPRYFKSFHHELSHKTYIDGAVLHNNPIRIADAERKVLWPEVQIPDMILSLGTGGSTHLGRVGSEHMSEARKGVFTHGRQLYSILRNNMQQTLDCERSWNEFFDNMVTALSTTSFTTSRFRRLNPDVGTIPALDEKDKIDDLRRRAQESLRRDRSRIQDVARQLVASSFYFELLPIDTEPENDGKIMVHARIQCRLPQPSADVSNLGRHLLKRASQQHEEPKFVIFEDGDLTPLKVVHVSERAMNHMIRTGEFDLGRLRFHIKNKMRPTQIVMHFGELAMHPISGFPQLLFTETTQLTSAKPTVFPSSMPSTRYTHGSRRLKRTAGSWQPPDLKRVQKLSNLNMFAKRQAGLGDDGAGEAATTAEPRHPPPRPATGSPSVSLGDGVNSSSSSLPRKRIGGVRDAFKALLWSPSRENVQMEPTELSDDLRQWLDRYRDVQARIENANSQSFSQNQNITAMPSVPDEQLAYSLQYYNVRPEEYAMYRQWVGLLQPSVVVDGAGGGAAAGAARPWLPPVGMSLGGYASSSPAGVVHEMAADHELPAELPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX62</accession>
    <name>A0ABR1VX62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666743.1">
        <property type="nucleotide sequence ID" value="XM_066814781.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047841"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="383"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="533" mass="60021" checksum="46A4C594A69A0E08" modified="2025-10-08" version="1">MLDLRIRELQTLLELERTLPKIIREAFPRNWSSWVGGMCMTLVNQLGPVADFTGDEASKKLLEAEKWNEEALEEHLRVNDRVSYARFVRTGAQICLMKIFRLQQLMESQDTPTDSSTATAMEEETKALQATGIKRAEEADAILSKHEINASWSDGLESVYHRQDLTRFYGSAFTSITAITLYLAQKDELFPDAASSVWSWVQKYKARSLARTIGVRSYDPPELINRIMETPETRTLYEQMLELKKRTEEADLMARFELRRQMDAHLELMKESHPLLRQLVDLHEATPFAISDIATLETQVGSPVVLVDWFYLPPYIADQAGQMLLFTARADKAPTMDVLPVTEADVLGWQEHHLFPFTWRRFREENLDTLEARRRFDAMLGGLIAPLAHRTKRGEVLVLCPSSTLHRVPLHALSLTYAKDSSGSSTATRTEALIHRNPVIYTHSHSLLRSCAAAAEYARHAPRDLHALFLSGIPAAEAAGYAAGRQSIRDLAGGFDVSPMIDSGAGKAKFLESAAGSRLIHLHTHCNWRAGDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX64</accession>
    <name>A0ABR1VX64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009398</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665675.1">
        <property type="nucleotide sequence ID" value="XM_066813713.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046773"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF16">
        <property type="entry name" value="ANKYRIN-1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="81"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="236" mass="25869" checksum="B1CD4448C37CE6A8" modified="2025-10-08" version="1">MAAPVGLATSLGFEKVVRHLFSRGANANKPLILSEELEDPDLTPASQNNVLHMACAYGAWAVAKMLWREGFCTNLSGRDAAGRTPLHYALHRGNWTWLLGPVEWLTELGDDPDQQARSLKPASLKPAEVLDAACEQMDFELALRLLDLGANARKTCSALVACCRCPPPGPRTHRAKYRAQIQLVRRLLRGGADVNLRWCDTTALRCAQVWSNTLVAGILQKAGARDTMIRISSRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZA8</accession>
    <name>A0ABR1VZA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666440.1">
        <property type="nucleotide sequence ID" value="XM_066814478.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047538"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="38892" checksum="8E7E59F3F8397DAB" modified="2025-10-08" version="1">MSQINHLQAVLQLLKFDRVAKRHPNYQLVTENDIKIARDIARRNGLVFPSNQLVDIRELVDGRASEQKVHELPEAIRSTASDDFLTPKRELRDEQSAVLEVRTPLVRRETVTRPSTTKTVPKDIAARPLTEYKWFPTAVAIAVIVLVFSALQYATSKSEFGVSSLTPATIFKSPHTVITYESSSSSSSSSSSSSPLFPTPPRKARVRKLSDADVGRVVASLKQATLASAPDLSRFRKEYRFFVTGTSVSDVVACLRGRGGGGGGGGGGGGPDVSPYFRFCVPDFEEMMEGAPGWLGSSWSGRGRSSVWPGRPAPRWKNGRSLPLREISGNGKLGIGDCVHRIFTIEPRVPGFLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7G8</accession>
    <name>A0ABR1W7G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666902.1">
        <property type="nucleotide sequence ID" value="XM_066811560.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044620"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051604">
        <property type="entry name" value="Ergot_Alk_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162:SF1">
        <property type="entry name" value="PRESTALK A DIFFERENTIATION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="293" mass="31108" checksum="0349335BD3A69271" modified="2025-10-08" version="1" fragment="single">MASKVIVFGPTGQVGSAVARTAAECGAEVWLAMRTTSKSIPGLSKEQEAKGPFHRVQADLQDPATVTEAVKKSGAKRAFIYLVHGAQDHLQGAITAMKAAGVEFVVFLSSFTILIEANLDDAFGPGGYVAVRPGCFMTNLLSEKAGIAAGHVELYGGSFEQDNIHPSDVGRVIGNILVSGPRHGHKNIVYLYGPEVRSLHESVARIGEALGKADLTITPVGPTEGYDNYIKLGMPPPYAQFMVDCLSTAGPDKGDGSRFPNYEEGVRNVQLYAGKPATTLEDWVTENKAIFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7P1</accession>
    <name>A0ABR1W7P1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666974.1">
        <property type="nucleotide sequence ID" value="XM_066811632.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044692"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="entry name" value="CofD-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240:SF0">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="CofD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="439" mass="46940" checksum="40CCA7B4B93BE86B" modified="2025-10-08" version="1">METPAVKGNGVVIFGGGTATNSLVDIFNDLRGSRACTLSYVIPISDNGGSSSELIRVFGGPGIGDIRSRLVRLIPAGPEGNADLAATKALFNYRLSSDPHAARSGVARCRGRPPRDLDGHLEREEGAHSARPHLPGIHGVRHLPPEPDLRHPPQTLVLPAINTSFTHHISAGLADKAVITGQNAISHPSAPTSLPDIAAAATQDVANQQAEDTDEHDLIEDANLPGSLPMLRKQYIEFSKSGEEDLSSRIERVWYINPYGHEIRPRANPKVLDAVAGAGAVIYSIGSLYTSLVPSLILRGVGAAIAAAPRGVVKVLILNSSLDRETGPSTDPFSAVDFVRAIVRALQESQAADVRQVAGSTSADEVRKYVTHLIHLDGDGTPKVDRDELARLGVEPIRVYGRRVDGMLRYDEGGLMRAIEAVIGTGREIMGRSRRNTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W885</accession>
    <name>A0ABR1W885_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667166.1">
        <property type="nucleotide sequence ID" value="XM_066811824.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044884"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="101" mass="11097" checksum="276DC90A3D5FCB06" modified="2025-10-08" version="1">MYPDPLEDFFMHSLRSVWAFVGRVGAVLRAAAADELLLQRRRRVLAASSSTTAPMPGGWVEEEEEVDGDSEDDDNHDSFGSDADDEAEDGSDSDSDNYVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8J4</accession>
    <name>A0ABR1W8J4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667290.1">
        <property type="nucleotide sequence ID" value="XM_066811948.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045008"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42858">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42858:SF1">
        <property type="entry name" value="LD15494P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="1">
        <location>
            <begin position="31"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="444" mass="47970" checksum="0AAA785F24E02263" modified="2025-10-08" version="1">MSSNTSKPINLQTGWPSARLCASAAILDGAQQVLTSETEAGPAMLYGPRIGHTPLRESLATWLSTFYAQSMAGNPTTKDRIAISNGASGNLANILQKFADPFYTRAIFLAEPTYFLACPIMEDNGFRGKLRGVPEGGPEHGGLDLGFLRQRLRETEAEAGRTAAESGRADAPVLKAGPLYPKVFKYIIYVVPTFANPSGKTMAEQTRRELVCIAREFDALVISDDVYDYLRWPADLTGGGDDALPPPPSRLVDIDRGMDGYDEKWGNTLSNGSFSKIIGPGVRVGWADCAPGLAFELGEVFNPDVQEAVPHHDGMHRANAGPHGVSVESSMDEKEGSTALAGGFFLYLRLPDDVPHARTVASVALREHGLRIAFGHLFVVAGDEGSIARAEGPGGISRCFRLCCAWHEEEELREGVQRLADTLASIRERMARGEAIREEALGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8L4</accession>
    <name>A0ABR1W8L4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase family M20/M25/M40 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667299.1">
        <property type="nucleotide sequence ID" value="XM_066811957.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045017"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="736"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="661"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="742"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="863" mass="95162" checksum="B5E92FADBDF6B38C" modified="2025-10-08" version="1">MEQEHTRPSQRSLSDLKAQSTSLRRARPPDIITMGDENRAPLRQNTVPDKMNKRESLVGLRSIFGRSKVGKDGREVEGPSTLRETSRSSGIRASLAEISNWPYALHSQKSDVSLSALSPLSLTHQSAVSSPLRPQPSAPRLKQSSSGKIKGPAASFTGTPRTGRGGAVTSWESPPLFQVYPQAIKHATLPAPSVSADALLRLHGARNSVMLREDMSSSTMNLEPEEGGDKKGDKAWKKHHRNMGSKNFLEWTTKIYVLVTSGYLLQYTNEGSFDRLPERVLQLTRDSAVFASDMIPGKHWVLQVASLMDPSGIPANDSRSLLAKLRGSERRHASNFLMVFEAAEDMDKTGKPKEDEIPAGLRSQSSQRTLVVRDPERFTNVMRQDFAWAPEKRRKSQQRESSERPSSESRDEVTLDAVLDDISTTESHYSSDGQVLDNLRDSNNRLSFISSGQRTYLTSEGSSPACSPTRASFTSHVDEHHPQQSEHHPETRLRPNAQAISNRRQSMQPYIASFDCRVEPVNRPHSTMLNVPNHKETSPQVSVRQSVPNFSVPNSAHKRFSSASGSDIADPVQWTESETPSKSGRKPPPTALALSRPLSVVVDQPSPHSPVSPQDVLARKLDAISSRKAADESPQSPAVSVFSTWVLSQSDKPSEPERLPSRGSSLTNESSSSTITLSDNKHSKRYRSMISMCPNKELAAEPSPEVERYILPTVQSLTRGSSHSSTLSHDVTSRAFSSMGNHDADRRRTMMARTRDSSYKRASLTAEERTPRRSLISLNEHVPVDSMAPSLPPKSAARTSPTLPSREDSPKPLSSAEQSNKLLLSRRSMPHLTNVPPPAPPPTCALPPIPKKYQEPTPRSLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9B3</accession>
    <name>A0ABR1W9B3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FYVE zinc finger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007874</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667531.1">
        <property type="nucleotide sequence ID" value="XM_066812189.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045249"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15761">
        <property type="entry name" value="FYVE1_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15737">
        <property type="entry name" value="FYVE2_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="211"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="356"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="550"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="630"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="640"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="672" mass="74721" checksum="3D81F8BFF3683EED" modified="2025-10-08" version="1">MASRKLGGGRVLGSGKGLHPPPTAASASPSVQRATSYYAPSDSTASLGSIGDSLASPASGSPGSSSPLPDFPQDLTSRVSLAGPSAGASNGSKLVCPICEEEMLTLLQLNRHIDDNHQELPDFQQDEVKTWFDKQVDKAKRFQPLSIINQKLRGLEVFESNESVPPPVYAAPSGPKAPAVLPEIPFDPDDIITKSHWQRPTMNDPCTEPSCDKRLGAVNGSINCRNCGRLFCEDHTMYQMKLSRSATHEPIRGYWYRVCETCYKSREGYNDHSGLTRDHTEAFAAIRKKRVERQTLEISRLEKRLTKLTQLLANPPADITAASNSGSSLLSPVASLSGQKTQRKAIEQSVVTWEDDAKVTKCPFCQQEFGSWTFRRHHCRICGRVVCADPQTACSSDVGLNVANPSVLASEKPDEASISLDVRMCRECKFTIFAKRDFVESIVHKPPDQRAYETLRQFERGIQLLMPSFQRALVPLQDGQGAPSRAQIKEASKLRKRLIDSFTKYDMAARRIRDLKTESPTQQRLQKAIYQGASSFLHMHMLPLKNLPRMLKQSSSSSSGSRKFLQPNGHTASPLRNHHTDGYLETASQTSETSTIISTLETEEKDLRERLIVLEEQKYMVQKMIASSQGGATVRRSQRPHQECGRTRAGDRSDQIESQRCGREMARAVYQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA75</accession>
    <name>A0ABR1WA75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667871.1">
        <property type="nucleotide sequence ID" value="XM_066812529.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045589"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="57875" checksum="4D0BDF4996570961" modified="2025-10-08" version="1">MQRTPPFTPPKGIWGNNTNNRPKTLLDRNLTRNPPDYEVGGLPGQVLSTGMRLDHTSPEFARSLNLGTNQGLRKSINSLESLQVRRTAWLTPECVDVPISHAYQCQPKAVRRRINILSTMESAGLFLDPEVGSGNGSGDGGGKLSQTRDELRTDLKFQKKLDEVYRTKSKLWKRIRAREFTIWPIHTTEHFVTIILRMRRSDPNAGPSTPYDEVAQFSILEPVGNLLMVKRIHRRLRRILCHDKIRIAEDAFCGLWYPKQHDGYSCGLRAYRMAKEFMERLSWILEPGPALAADPPDAVAGPVRALARPDGHDRGPDADGGRGRGRLRAHAVGAALQRQLQRGPGAAGDDDERRPPRRRARRLAGPRRRRPRPRRLRPRPDGRPAVAPEAGGPQRGARADPAVLRAPGPAAARGGEPDIQRFEGQAAFNPVQNPGSGPGRNRDQIFLDALANVTLDNQLKRRGESETGEEPAKKLTAKQWRRKRTKVTKLRKGRHDRYGPAFISAPAFRKVLGGRIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAZ1</accession>
    <name>A0ABR1WAZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668143.1">
        <property type="nucleotide sequence ID" value="XM_066812801.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045861"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="140" mass="14764" checksum="35409421FCCB70D3" modified="2025-10-08" version="1">MPKSDFSGCPRFPDAVGTVAPGDDPEFMAAAAFVALDDMQLDAVVEVELGRDIGSSVFGSGNVAPSSMTDRIGGRAGDGVRVGVGAANGARLFACENASVEAVMVTVANLERTRDSEEWQLDRSLGTSYLYTWLMKQSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB02</accession>
    <name>A0ABR1WB02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667176.1">
        <property type="nucleotide sequence ID" value="XM_066811834.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044894"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="33646" checksum="48A540F70855C4A2" modified="2025-10-08" version="1">MVASNAPEVVEGYVLLRLWGSIQGSDQGCPFSREPNWKKPMCLQFISLTQAAHGTDRYKKAETSIENGLLAISSGDQEPLKDLIAHVEKLTPHMDDSLDFTEGYDPDTPFFLRRERRIIAWKDWVDQEPLKTPTDLENAERVAEAIDWAQRECKADLISISFGYMEDQPPIAAANSGANTTQLFPARHKSVISIRATTSKGYIADFNPPLDPDESTALATLGVEVPSAPPSHFITQRTSVKSGTSIANAIGVGIAGMLLAYVNQQSNRRSYNDVRKEIYTRKGLLGLDALMSTGWRTGEWVSAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBV9</accession>
    <name>A0ABR1WBV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Citrate transporter-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008805</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668462.1">
        <property type="nucleotide sequence ID" value="XM_066813120.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046180"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43302">
        <property type="entry name" value="TRANSPORTER ARSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43302:SF5">
        <property type="entry name" value="TRANSPORTER ARSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="499"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="545"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="594"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Citrate transporter-like" evidence="9">
        <location>
            <begin position="80"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="355"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="629" mass="68117" checksum="56C195FD018B671F" modified="2025-10-08" version="1">MDMSERPPPPDISQISDVIVSFPFHIPIPVPRILWEGFLGVLSKLRLIPPRDHAKRSKDEARGHWTTLRLSISTITAPVYACLFLLAILAIGRTEVYDGLLKFLAFKVLQKGGAKGHRLFLYLYCFFFALGTAIGNDPIVLSGTAFLAYMIRASSNIASARAWVFSQFAIANISSAILVSSNPTNLVLAGAFQIKFIDYTANIIVPVLFTAVLLFPCLLYLVFRDEKLVPHVIDMHTLPDPEKEMAPVNPNIPHAGAGEDRSPGIGEILNPYLDRRHAAISVGIMAATLISVLVINAVTASGGGKPTPVMYVTAPAAVLCFSADLFFGWRHRHATRAVAEKGRLAEERAAIEQEIRGPTASSSADPAATDTAAVTTNSSSDTEGSPSGIHGDGAMPEKPPRGISDEALAAAVTRELEARKRQEAEKPATLVSLTRRAYTWWRETFPAASIVMSRLPFELVPFAFAMFVLVQGLVTRGWVPVFAYGWDAWIKRTGVVGAVGGMGFLGVVLSNFTGTNIGTTILLCRIMQAWQQILASGGRDTTDRTFWGAVYGMALGVNYGAFSSALCASLAGLLWRDILLSKGVIVRRLEFLRVNAPIIAIATAVGCAILVGEVYIMRKDTPFIMLSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC58</accession>
    <name>A0ABR1WC58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667520.1">
        <property type="nucleotide sequence ID" value="XM_066812178.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045238"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="37404" checksum="EDB27BD1A29303CE" modified="2025-10-08" version="1">MAVSMPSTKHKGANSPASGKDATTPGGSETKVSPQRKQWNRCDEKPEGLAYNPFYGKRRGTSWREKQNDTVKGIRLNWVCRYPQKKKDAATAAAAASKKTDDDHCAGNSVEALLSMFAAHLGFAYVWIIRGPRIPTPFIDNNSNGAGAREPTPEWSVGVCFGNEEKKCMVYGNIYVTVGAENKQMVTGLMKEGCETIIPGGGRSLDLWVADADMPRPFAPRKKKPRKPRYKKNKNKKTKVADELKKVPATTTPAERNKEKKKAGEDGKPKPKVLQASAKPENRVTKPKHKKKKKKEAEKKEEEGAGTKKKETEQPGNPDSPARNCQELRHRCPQAHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEP1</accession>
    <name>A0ABR1WEP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Inosine-uridine nucleoside n-ribohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008748</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668405.1">
        <property type="nucleotide sequence ID" value="XM_066813063.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046123"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43264">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43264:SF1">
        <property type="entry name" value="INOSINE_URIDINE-PREFERRING NUCLEOSIDE HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047246770" evidence="2">
        <location>
            <begin position="23"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="3">
        <location>
            <begin position="27"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="319" mass="34345" checksum="855D573A1D8496BF" modified="2025-10-08" version="1">MIAGFLLTAYAALSLIVTTSLSSPKPIIIDTDIYSDVDDVGSLAVANVLHNCGLADLRGVVINERSKYGALAANTINTYFLNGDIPIGAIRPLSDDTFFDKYRYLDSLGSAQDNSITIISIGFLTNIAELLESPPDQHSSSNGRELISSKVKELVVMGGTYPAGWEFNFGGLDPASTKAVVENWPANVAITYSGAELGGGIYSGYLLPTHSPPNSPILAAYQWYVGRGSTVRESWDPVTTLYGILGLDGFQKLGFKAPLVFANSIGYNSVLDNGTNSWVYDSKVTNQHWLELADGVTNSTVSFLLDQFLVHNPLDSRCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WG33</accession>
    <name>A0ABR1WG33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668523.1">
        <property type="nucleotide sequence ID" value="XM_066813181.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046241"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046931991" evidence="2">
        <location>
            <begin position="21"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8081048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="169" mass="17502" checksum="AAD8237FD4D2CAF7" modified="2025-10-08" version="1">MHAQQFFVLLAAVGTTITEAHPPSNVNQTQTPHRPPAPRHINGGSFECNTARVRIVAGLQETRTNVEDIADAATKDAANEGINQSANAIKSIAVAIFSGQTPPGDARLITEAGLNVTQAALQGATSKFLSACSIDGKKKKDTSDPAVVAASATFAEAVAAAFDVVEFCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WGF0</accession>
    <name>A0ABR1WGF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Purple acid phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008986</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668643.1">
        <property type="nucleotide sequence ID" value="XM_066813301.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046361"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PAPs-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="ACID PHOSPHATASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953:SF153">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044989238" description="Purple acid phosphatase" evidence="4">
        <location>
            <begin position="23"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="5">
        <location>
            <begin position="198"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="6">
        <location>
            <begin position="418"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8081168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="492" mass="54789" checksum="F0C0FDDF225CED8F" modified="2025-10-08" version="1">MASLLSLAKGLPLLASCASALATLPAMLDDRTTPVQQRIAIKGPNVMSIGWNTGLTPATTYYYKILSTNSTVEHFFSPRMPGDKAPFAVNAVIDMGLYGVNEFTIGMDMSKRHLIPTIEPAPNHTTIQRLAANIDDYELVLHPGDLAYADDWICPYFKEWLPGCSAKAFLRNLLRHPSSIWDAISNVKVLYWDVKRGHTHDAFQAILENFYNQLAPIAARKPYMVGPGNHEATCSEVFARANLNKKVCPLGQRNFTDFMTRFGQTMPTAFASTSADPRAKANADKARMLANPPFWYSFEYGMVHFVMIDTETDFASAPDETWLESGPFGVPHQQLEFLEADLASVDRTVTPWVVVSGHRPWYTAGTEVCTACQVAFEPLFYKYGVDLAILGHVHNSQRFHPVYDHTADPKGLDDPKASMYIVAGGAGNIEGLEEVVQQKLAAFTYADDFSYGKVKFLDENRLQVDFIRSSTGETLDRSVLYKSHKEQFVVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLQ5</accession>
    <name>A0ABR1WLQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonuclease H-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668877.1">
        <property type="nucleotide sequence ID" value="XM_066809954.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043014"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040:SF1">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="96"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="381" mass="42646" checksum="5ED3D402B7A681D4" modified="2025-10-08" version="1">MNAARRHVGRAFSSTPRTLRSVAQKRTVFNLKGGSKAGAAAATEAVAPAAAAAPIAAPQSLKKLGRDKKPELPAVNAPPPGFVPVELPGRAKKIQTFFIDNPAGVSELADRLWTQALAGRANDDNCLYVDLEGADLCRDGSLSLLIFYSTRLREAFVVDVFLLQAAAFTTRGSKHDVSLQDILESADCRKAFFDVRNDSDALFWHYGVGLRGCEDIQLMENASRDDGNRNLVSGLMKCMTKILTVAEKEEWDNAKAAGKDLFNRGSFEVFDVRPLSPEIISYCVGDVYYLPRLRKAHWKKLSEEWREKVMEETKARIVESQQELYQPLKAAMARGPWEADWVWVPLEEYKPQEYKPRASRPAPRPTWAKKKRREVQLKGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLR4</accession>
    <name>A0ABR1WLR4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ankyrin repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668892.1">
        <property type="nucleotide sequence ID" value="XM_066809969.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043029"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="558" mass="62563" checksum="68792FFC8291B77D" modified="2025-10-08" version="1">MQNCVTFNRDKGIDPQTASPLVRLPPEIHLTIAMESDSDEAIFALLRTCKTLYGVYRDLLYERNIRHDDGSAVFKIARNGQVAAFENLERVAKTMEEGMPALNRVQFISPEGQTVIGSSLSDSASCPFIPENSFTPLHWAAAGGIRTPSNGSSPRERLARLSANHWKTTVCAGHVEASRRLLLAEPSAFDYPQKEFNPTMFDVAVIYGHVYMIRFLIQSGHPCLTINTLEYAALSKSIRTSLRCLAALGQDIFMALDKFIRVQFPDIEAMQLIQDPAMRIDLGRPAPNDPSTNQATALLAVALSRGWVVAEKRDELRQLVIFLIQSGADVNYHSTTLLGGWHGTCVLEAALYINYEDGSVAEELVNRGARVHRGDGEESLAILYLSRMRRDPDRVRDFDIIRADGSCAAVHKLELLLKHGAVLDQNCGFQPLEDAYLIATTGQWSYNAAGELSFLKVLVKNGVTRDPAGGNYQPHSYSYLFNIIFQRHTNRDYMVPPYNMDHSFLYRALTSGHYDIARVFIERGGTCFGVHDRMEDIDGHHDQMPKDIREWIDSIYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WME8</accession>
    <name>A0ABR1WME8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arrestin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005928</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts with hulA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669166.1">
        <property type="nucleotide sequence ID" value="XM_066810243.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043303"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="4">
        <location>
            <begin position="186"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="432"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="568"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="432"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="469"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="588"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="620" mass="68139" checksum="84AABCC0066F84EC" modified="2025-10-08" version="1">MPSFNPFTSVASRNACALFEIRLESDFIVFRGSTDEASGQLLKGVVVLCLREPLRVEDVHLRLTGSARVAWMEGKQTPTGIHNQKIDRTTTVLRHSWPPFVFGNDHHSHILAAGNYEWPFELLLEGNTLESVEGLYQTGISYFLKATVSRGKLAKNLHAFKRVRIIRTLDPAALEFNHAMSVENIWPNKVEYSIVIPQKAVVFGSHIPLEMRFTPLLKGLEMGEITVRLLESQEFSVPGYSALPRVHKAEREVTNWHFEVKRDDHWQDNIEETGQEGWKVTRDLPLPQKLSKCLQDCTAAGIKIRHKIKLTVALKNPDGHVSELRATLPVTIFISPNISLDDDGNVVSGEAQEAAEGTVADSDQSNMAPPGYGLHVLDQLYENVDPSITPNGMQSGINTPFYAQSRAGSHENLSQLASGAVTPAALSSRLQNVSLDPNNRNNSYTSMGSHSGINTPSHNYSHDGDHTAESSLPQSAELSRQTSAEEHHSPETSGHSTPPEHLDLPDVDMAQLSKVPSYNTATRTPLARNSSFSDTVTLPDYFSVMSAPSSPTRAPVNDPLATITEDMGDSAETLQPRPSRRPSARRSNSLGFASFLSSHSIGDHHGERLSRLIPSRGAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMQ9</accession>
    <name>A0ABR1WMQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="1">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669305.1">
        <property type="nucleotide sequence ID" value="XM_066810382.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043442"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138:SF5">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="2">
        <location>
            <begin position="64"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="470" mass="52267" checksum="A7B7141B25319260" modified="2025-10-08" version="1">MTMMRRPVVAMSGVLSCTAAKARQSPWIATTSRQLWWHCCYSQRGFSTTSRTLQQQKKQSDALRILFCGSDEFSSASLRALHEEKERNPGLIESIDVVVRPGKRVGRGLKLMQHPPIRSVAETLGLPIHERDTFTNWEMPPAINLIIAVSFGKLVPNRLLQAAKYGGLNVHPSLLPNLRGPAPLHHALLRRMDATGVSLQTLSPHEFDKGLVLVQSWDDDLIRIPPRCTVPQLLELVTPVGAQMLVQGLRDGVHVPPLEEQSGVAKSQDQDQDQAATIFHAPKIEPKDRALHENFTFFDQEQADKYPLESAGDLLPFPERLRQVGPVDSIALAQRVIGPLWFLVMDQKSGAIKRIIIDKADDDIVLRKLPAHLPSDVPSSSGISFEGSIIFASETQPDNGHWSSASLLWYILEEGDDSIYLFDGPGSKPVRKRQFRCLRVPSLKVDGQAAKPARQVLEHFERFSGLPKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNW3</accession>
    <name>A0ABR1WNW3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669710.1">
        <property type="nucleotide sequence ID" value="XM_066810787.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043847"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="638" mass="61125" checksum="1D6049564FF4EDAA" modified="2025-10-08" version="1">MGTTANLATSTTADATANVTSSTTADAATDVASSASANTAVSTTADVTTSTATDTAASTCTAPDGTGTTSACTTANTSVSAAVRATTDTATSTSTASSGGTGTHSISRRDTGRNSSSHSDARSVLALAVDESAQAGVEAGADTAKQLGEGIDVDISRVRSDPNVQIARNATNGVEEAIGLRLESREDIDHEVAATEALDDLLLSQQARDEAAAGQLEGRHVDLQADDSANADREACRSALAPALRPPMAPAQPLGFAVEAADETGDDADGAGEVAADTKATTEAATEVATEVAAKAASNGSLTTSTGITLNVTSSTGTDAATNSASNVAASTSTTSDATTEAAANLTTGATSKMGTDVAAGTGTCTALDITASTSAAADVTTEAATDLTTGTNSEMATDVATNTTAKCAAGTAADLSTDTAAKVSADITTGTSTSSALDVAACTSAAANGTTGTTSKMGTGFAASTALDITSSTGTGTTLNGTTCTSSSTSTSAAAISTGTTANRSAEAASNVAANITASTSTSTSTALNTTTEVAAGASATLHITAIAGTTANGATGTGTTSDLTASAAADLAAGTSTTSYLSASAATNATAGAAADLAAGTDFAAGGVCALLVESVGVAAESEGEECELRSGLHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPK5</accession>
    <name>A0ABR1WPK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alcohol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005681</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668919.1">
        <property type="nucleotide sequence ID" value="XM_066809996.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043056"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF138">
        <property type="entry name" value="DEHYDROGENASE PKFF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045873092" evidence="3">
        <location>
            <begin position="21"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="340"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="644" mass="68884" checksum="7F7A9593B5D8F71E" modified="2025-10-08" version="1">MYASTRLLILNALSLGCVSASPLLGSLLNPLTGSLETATSGLIEATIGELKGTLGDQESFDYVVVGGGTGGNTIAYRLAEAGFSVAVIERGLSYEVGKPIVGAAPLGDIIGVGSNPLDSIPTVDYGLVTEPQAGGDGRKIHYTQGKCLGGSSALNFLIYHRPDKGSMKTWADAVGDQSYEFDALLPYFEKSITFTPPNNNMRPANATPVYYESDFTAKQENAPLQVSYANWSPSWSSWAAKGFEALGIKLTGAFNQGTLSGYHYSQLTTKPKDQVRSTSADFLYHAKDKGTKGKLTVYLATRGKKIIFDANKKATGVEVGMDLLPSYVIKAKKEVIVSAGAIHSPQLLMLSGIGPAEHLTQHGIKVIADRPGVGQNFTDHVLFGPSYQVKIDTLNKVIGDPVVLAAAIAEYALSQTGPLTSNVAEFLAWERLPEFVSANMSQATQDALNSIAPGWPHIEYFSAAGFIGPFNIPWMDQPKDGKMYSSVLGALVAPFSRGNVSLASSSPNDAPKVNPNWMTHKADQELAVAIYRRIRGLYETEAIKSVRANAAEYWPGLGEVQTDEQILAHVHKTLMAVYHASCTNRMGRRDDPTAVVDSRARVIGVSGVRVVDASAFALLPPGHPQSVVYALAEKISDAIIRGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPS6</accession>
    <name>A0ABR1WPS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphotransferase</fullName>
            <ecNumber evidence="6">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006313</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669551.1">
        <property type="nucleotide sequence ID" value="XM_066810628.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043688"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF24">
        <property type="entry name" value="PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="7">
        <location>
            <begin position="85"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="8">
        <location>
            <begin position="248"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="510" mass="54949" checksum="966DA7954086856D" modified="2025-10-08" version="1">MQSFTPAIVILRKAMLAALKTLVRGRSFLQALFAFWISPAVLKEHHVNGATLQPRPRTIEDFLKEAEDLLMGPLDGGRLSDFSSQLKLQQETGQFLALDVGGSTLRVALVELNSREMPGRECSIVRIDTFKITPELKLLKGMAFFDWMAARIKEVFSDGDTQGRDPESPIPMGLAWSFPVEQTSLGSGLLLGMGKGFLATDGLLGQDLGAILEKACKNAGLNVQLGAIVNDGSATLLSQAYVHSSTRFGLILGTGTNIAVHLPVSAFGRGKFGNRPETWFDSASHVIVNTELGMFGKDILPMTRWDKLLSAAHPRPEFQPLEHFVAGFYLGEICRFALIEAIEETGLLGGVVPPSLEKPYSLDTATLSRIEVDQSSTFDTALPYFAATHPSPVKPTVSDLAAIRALASFISRRSAALLAASVFSLILRAPHPLVAEAAAEHALERTKVAFNGSVIEHYPAYQTNCQRYIDQLVGGQSKHKGAIELVPALESSILGAAVALACTDGEQGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ64</accession>
    <name>A0ABR1WQ64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670189.1">
        <property type="nucleotide sequence ID" value="XM_066811266.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044326"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF11">
        <property type="entry name" value="ESTERASE_LIPASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="6"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="159" mass="16972" checksum="FF89D7B1881BBF01" modified="2025-10-08" version="1">MSQPTILLLQGSFQLPEVYGRLTAALEKRGFPVVHPTLPSLSGQDETDFASKSLATDADQAQSILRRLVEDEHCNVLVLMHSYGGLVGTEGVPEDLSWSNRKSRGLAGGVFHLFFFAAFILAEGRAAAVSGGVRPKRRVYGAPPGFRPLGHAKQDGGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRD2</accession>
    <name>A0ABR1WRD2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669564.1">
        <property type="nucleotide sequence ID" value="XM_066810641.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043701"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="168" mass="18849" checksum="20FF9EE4D79D6293" modified="2025-10-08" version="1">MEWDSRSQTAAIVFMPCKTDCTGTLDIWDIWDIWMHGPRRNDDFNFPATKPALPPDLQPDGSKTSPTTYVENRALPRADLLPLHRFPRLSGSTVASVLRHVSTALVTRPPGPPILGIANRRATQDFEGKEQTSTTLAHPASPENTTNRKMLDNSRRHASHAFQSMTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRL8</accession>
    <name>A0ABR1WRL8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669443.1">
        <property type="nucleotide sequence ID" value="XM_066810520.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043580"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="803"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="930"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="805"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="856"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="979"/>
            <end position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1003" mass="109211" checksum="E42F27CCC957F37A" modified="2025-10-08" version="1">MQTVPSLIASGTAIAAAATGLVFGQPAENHTFQPRGKPQESGKHPTEIRYRPYHPPSLCVQARLVPPWVNRQPTDSNIPPSWVLMQPYGQGARSGGRFKHKQRLPRLATWRRSSLRQSDAGSGTAATEESRDSLSSSNGSWIRRLSIRPMSQHESVKSSLGPDSPSLFSPMDRVNQSSGKQLTAEAATPPASKFSHDSRARPRAQTLGLPAHEPALDISANDNSTWRSFFHARIARIAARASPISRDSQPGPKRICLERASSVQGAYLVSPRSVLQGPPLPPMQELSWDADTLSQCYAVQNSQALHVNAFQLPTNWISRSGSLRRRKRGAIGTGATDETLRQVSDPTPTVAHSGCPQGSPHVGRANSTGGAGTPSRAETDLAAIFQPPHQSSNSPLPSLSRLSSFHMDLSRMGSPTNMMAQSNLDSKPASSANPPTLRVNSNVSHSRTLERASTVASSDYHRGFTSGDDDDTDFKTDTPYDSLRTAGSGRQRTLDSPVESMFDESPPSTAGNNKPKRLSIQEILGPTYDGGNRIMEEDESLPTPVGATFDEAETHFRLASLQGDESFKYTSITPDLPRVSTGTDFSRLSFDEDDALDWAREDEHPVYNHLSPPSSMNSRGGSPSLRMALASITGNAGSNPDLMRNNERPRSNIFDWTETAQHDKLEGEDIIDNSKPKFGTWGLGSKNVSEDWDEDFEFEEDADAGFSEGVKAGNRLSMVVPASIAATQPTVKAHSGQIRELREMDMLTGSSATLWREAEGIIALASPDEDDADTSATNVQLENLEPQLADDRFIDEGFDGSALEEQSHRGKISDQMKTAVVKERPAARRRSVFSPEDDIFGNFQQSQDGACETPKTPDTQQAKLPFSPSSVARSLMESMQLRRREPTDGSDDESANGRLNFDTNSLKELVKRAGDLRDSLSDIVRKADHITQTPVRTTPRRDRSEKNEDGSPAFTRVFNDPSSSSPAKRIPHSHSSSSVLSGGTMNTPSPNGLSQRLQMMTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWI1</accession>
    <name>A0ABR1WWI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Pisatin demethylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002485</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670418.1">
        <property type="nucleotide sequence ID" value="XM_066806800.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039860"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8087524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="532" mass="60160" checksum="2889084010491FA1" modified="2025-10-08" version="1" fragment="single">FHKTNPTPDMSSSVASSSTLLWALVLFIATHAGWTVLSHCRSPLRQFPGPFLARWTNLWRFYHTLRGDMHLVNLRAHQKYGPVVRTGPNNLDLDLPGLIKTVYSSDGRWRKTEFYPPASNVMDGRVVFNLFSLQDPAEHARQKRPVAKHYSPAGVLTLEPHVDETIRLLCRRLEERYMSANDGEGTSELFSSGFVIGQWIKMCKLKALQPLCPYTWDVIGQITFSKHFGYLQAGHDFDGHIWLSNKGADYLASVSQIPWLDRLIDKNPLIPVAGATALLGSTLKYLEERYAGRDGHSTHQRDFLDKFLEAQNEHPDVVDRCQVVSYLAINMLAGADTTAIAIKAVLYYALRTPGLGLYCRGVLSYAEVRAQVPYLEAVVREALRMHPGVAMVLPRYVPTGGLELPGGLGVVPPGTSVGMNPYVLGRNQEVWGLDADEFRPERWLRRDEQEIETEEAYAVRLRAMNSADLTFGAGSRVCLGKHLGLLQVYKVAATLIMLYDMELVDPTKEWWVRCPFFLRQKGPEIRIRRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWY8</accession>
    <name>A0ABR1WWY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Trichodiene oxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002604</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670537.1">
        <property type="nucleotide sequence ID" value="XM_066806919.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039979"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8087643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="60154" checksum="844CF46CFBE2230C" modified="2025-10-08" version="1">MTRRIKVSACLNSTDSQIDVALSLSSSLLSICSTGAMSIMNPAVEWYMLVVAVLAYYATLAVYRLFLSPLARFPGPKLAAISRWYEAYYDVLQNGKYTLKIAQLHKQYGPIIRISPYELHVIDPAFFETLYRMDGRWDKYAWTYDAFGASDSTLFGSGHDAHKLRRRAIAPFFSKPNVLARQDTLQRNLDKLCRRISNLNGTTFNLGAALSAFTRDNANEFIVGKTYNELDLDDFGVGLSNASQGAGVFWRTTKHIRWFGPLLRAIPISLAMKSADDGTKSFLRYLQQSEQDTRDTLAAATSSSPDSTVRNTMIYEIVHSNLPPQEKTLDRILQEVASATGAGFETTAAALRLILFHVYTSTEILQHLRQELAPITSDPSGFLPLKELEQLPYLTAVIMEGMRLSPAIATRAARITDKDLHYQQWLIPAGTPVGMTTYLMHIDETLYPEPMRFVLDRWIGPKRASEATYAPFSRGTRMCLGMHLAWAEMYLILAKLIPQFDFAIVGATASDLEMERDNFGVGSKAGCNLNARVTTLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX92</accession>
    <name>A0ABR1WX92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670659.1">
        <property type="nucleotide sequence ID" value="XM_066807041.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040101"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF34">
        <property type="entry name" value="OS04G0183300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="491" mass="53501" checksum="F84E63678C45E279" modified="2025-10-08" version="1">MDFDPLTTTATELQQLLKEHEITSVQTIERYLLQIEQHNYALNAFISLAPREKLLGQAAALDEERRANCCRGPLHGIPIDCFITSHEFGMPTTAGSWAFLGAKVTKSSGLVQKLMDAGMIILGKTNMTELCGMKMMNSPGRSAVKGQTLSPYVGAIEDGDSILGHSSPGGSSTGSAVAVAAGFSPLAIGTETIGSIMTPSSRAALYAIRPTTGRQDTSGMYRMTEFFDSYGPMAKSPGDLASLMEIIHGRSFQAHTPAGKWKGLAVGFVNPNVWKLSPEMCKQKEGTSEQMVDDYAAMIFTLQKDGCVVKYPIELQECSVLAVGGQDAIMPIAYWEFKHIGLPKFIEEFDECPVTSLEGLVKFNKDHAEQAMPSPYTDQTDLIKAQAMNKPEQEIKLLGEKLRAKARKILDEIYEKENIDLIAAPVDSAFCIYAAAAGYPLGVVPLGQLRYNGRPFGLCLMARADGEETLLRFMSSYEATVPPRPMPKLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXE7</accession>
    <name>A0ABR1WXE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002796</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase C56 family. HSP31-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670729.1">
        <property type="nucleotide sequence ID" value="XM_066807111.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040171"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03141">
        <property type="entry name" value="GATase1_Hsp31_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF11">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="6">
        <location>
            <begin position="69"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="208" mass="22058" checksum="4BBBD48F5EE7D71C" modified="2025-10-08" version="1">MAPKVLVVLTSFGHIEAANSPTGWYLPELAHPYNVLASKTELDAESVEFLKSKTDVWKNTQKLSAFRGKAAEFDALFYPGGHGPMFDLATDADSIALIQEFVAAGKPVAAVCHGPAVFTNVTLPDGTPLLKGKEATGFSNVEEDQAQMTKLMPFLLEDKIKEVGATYKKADEAWGPLVLSVDGGKLITGQNPASAKGVGEAILKAIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXZ4</accession>
    <name>A0ABR1WXZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Palmitoyltransferase</fullName>
            <ecNumber evidence="13">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_002967</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Palmitoyltransferase specific for casein kinase 1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 13">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Early endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="13"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670900.1">
        <property type="nucleotide sequence ID" value="XM_066807282.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040342"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0564">Palmitate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="488"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="63"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="130"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="183"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="15">
        <location>
            <begin position="390"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="538"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="553"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="599"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8088006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="687" mass="75704" checksum="661E21E0BD57D230" modified="2025-10-08" version="1">MSQSNGNSAAGMPKQPASKAAAATPKVNAEAPEIMQVARVGDIPTMEKLFEQKDYDATFTDEEGITPLHWAAINNQYGMVKFLIDKGADINKKGGESVATPLQWAAQRSNYYTVNLLLQHGADPLITDSQGYNTLHISTFGGNILLITLLLHQGIPVDVVDSYGHTALMWAAWGASVHAKDEQGFTALHWALVKGSPPCILKIIEYGADRFAKTDTGKTPAITAQDLNTVNAWHRALKECGYTEDGHAAIPWWPGASYFLQDKRSFMNRFLFVLPVAMLWSELIVLSYLPIILSVIEFGPPDMRHLHKTPWLTGIFAASLFLVGTSWLWSVLPGTFSDSFFLNVVFAAFFGMTVHFYISCMVYDPGYVPKLNGIAEQKAVIDELLSLWKFDEANFCVSCMIRTPLRSKHCKKCQRCVAKHDHHCPWVNNCVGVNNHRHFFLYLISLTIGILSFDWLLYSYFSTLTSSASDKCTFFSESVCKVLNADPYLVLLGIWATLQLTWVGMLLFVQFVQVARAMTTYENMYGISDGASANHTQGFTSTGAPLDPNHPDAGAPPARRTTRSATVPTARPATATARASSSSGAASWALTPSSRRRQAGALRPAPARTGARTRRTPYSKGYMQNCKDFWCDPAPMFGRRETGEAMFGGRKINWTDVYESPALMDAGLASSGRRRGGYESVAGDDQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYP6</accession>
    <name>A0ABR1WYP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671142.1">
        <property type="nucleotide sequence ID" value="XM_066807524.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040584"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391:SF3">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04300)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="834"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="899"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="717"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1081"/>
            <end position="1120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1120" mass="122752" checksum="E50882F5F3D50873" modified="2025-10-08" version="1">MSSSIYTVSPASLHDHRGSPRDRMNVPHHSPPQNTFYHQSLNPVDSQQLLSPHSSHLQSNSASPTGASNTPAESTTTSTTYQPSDFSEPDDPFFGADFNDIEGSAPAFLGPQIAHLGGTGNPELATYTSSLPFATQVADFGTKPAEHQSQPNIASSWAENQYSQTTFGQFNSEEPPPRDSTSFDHSSSAPQLTPDSNSGGWSSDDNHDSLAPRHANMAGQSPRVTVSLWGKDGQPPVHAIERTFEPEVPGSDPAHQLGSMDDNLSNVTLHGSSSNVSHEAQGCWIPDHSTRRLGLAPEARSQDRTTSINQLAATRNIEERNVDVAAWVSDATEKTTGFPISDPETSSTPVQSNVMDDNIPSTEVPLGDTTENRHQPGRTYYQTDGSGGQITQADLDIMRQGRNWSDAPVVHPISHNASAKLQPESSQAAIQRFEEMCHDNGSIVSRAATWGREEEAYQALGNSTSRRPSILQRIVSKSSASNLLKRRNSSTTDDATSDEANQGERRESKDSLAPPSRATSWTKQRAIPSINTTLVGMAQSAASIGTAHAGSGSINAATPVTSPKSPFGFPATVRNTIRRPRSKTEMPQRGNLDSTPNIVGLLKKQGGPPVARLAGSQSTLDVDDEDEDEDDALDDSDIKVEPGEVEDIVPTFEGFQQHILRLNPGLDKTNDYLVERIAHQMIVRYKNLQNLKIKHLKAANTGSCMCGSLCMAQGGSAAPLDSRGDARGVDPLSARSDSPDGEATPLENGINAESFPSGIPIPPTSSLPAELECQLCYTHRKFQKPSDWTKHVHEDVQPFTCTWAPCRDPKMFKRKADWVRHENEGHRHLEWWTCDVEDCHHVCYRRDNFLQHLVREHKFTEPKVKTKTAIKRSGGNDPTWQKVERCHQETRSRPQDEPCRFCGKTFPTWKKLTVHLAKHMEHISLPVLRLVENGDLKEDTIISPVQDLPPRNFNLLPVSKQGPQQFSPSRPHAVSNPSPVEFQQMNNNMYTYSDMSRATLDTSYYNQPTVSAQYSAPITQSHGLAMPQTAGGFVQQEQYHPMPVSTAPPYGQPVTTFMGGQNQLEAFPAFNALGMPDPMGNQVSYDTSTDPTMQDHYSNPGSVSPYTHSPHQGHSSFYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYZ1</accession>
    <name>A0ABR1WYZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003283</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671216.1">
        <property type="nucleotide sequence ID" value="XM_066807598.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040658"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF361">
        <property type="entry name" value="TRANSCRIPTION FACTOR SKN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="371"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="326"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="476"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="592"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="479"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="598"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="620" mass="67516" checksum="D25ABDC568058180" modified="2025-10-08" version="1">MPEGDMAVAQGSSNNSSDFVRKLYKMLEDPNYSEVVRWGDGGDSFVVLENEKFTKTILPKHFKHSNFASFVRQLNKYDFHKVRQSEENGQSPYGKEAWEFKHPAFRADAKNNLDNIRRKAPAPRKNQATEDQFSSNTQIAALSETLAATQQQVQALQDSYFEMAHANKVFVDEIMHLQKMIKAQNSVNNELVNHLGKIDHERRHARATSNHSNQFNGNNIMSDGTEEPPAELRRARDILNSVSGDHIPEKDLRQMSIQFQQIGASPDSASSSSMMGPPGSAGMQNNYIHDPMNDLRHMVYPVGQTIGIDPFAAEHMGNIPYNRPLSQNNMGPGQGPGAVPEPGPAAMPTASPPVGAPGAQSTSPWGQKKPRVLLVEDDKICSRIGSKFLAQYDCGVEVARDGLEAVNKINTNPSWFDLIFMDIVMPHLDGVSATAMIREVSPRVPIIAMTSNINQQDLEMYARCTGEAIHQGGYDWQTEEASSQLSSQPPQESVMDPMYSNGGTGQPPTPGPYANPNMSLPMSAASSGPIAKFETTPHFLAFSGAASACFAQHGTRSGGYLTAGSGGPMAMTPGGTQRPQQYAGGMIPAMSGQQMGHMPDDGPPEKRQRLYGPGPQGPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ56</accession>
    <name>A0ABR1WZ56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671343.1">
        <property type="nucleotide sequence ID" value="XM_066807725.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040785"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="193" mass="20217" checksum="CCB92CB9D6C9541C" modified="2025-10-08" version="1">MILKSPPGTVVDAGFDSETEGITAVAEEEAAREDAATVEEAAVEDAGTLEEPAALEELAATDEAAPVEEAILLALEKAFEDAIELMKLLEGIRAVPLVLPVADVRNSDKLVLAAEVAGADEVTATEEEAVCTRDPDADPEATSVGMLEEAVLSGLDPTRLELLDWLDELLDSPFAELDVGAADWDAVATSEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X071</accession>
    <name>A0ABR1X071_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671697.1">
        <property type="nucleotide sequence ID" value="XM_066808079.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041139"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059009">
        <property type="entry name" value="Znf_C2H2_17_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059095">
        <property type="entry name" value="Znf_C2H2_17_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26177">
        <property type="entry name" value="zf_C2H2_17_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26176">
        <property type="entry name" value="zf_C2H2_17_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="371"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="530" mass="58199" checksum="15A53970762B9C20" modified="2025-10-08" version="1">MEQPAPTWNILEDSWFVQHGPHSDYSTFSHGNFASGPFLYSQTVPSDLNGSVWDTTTAEGTQNFHGDAEDFPFSFGHITPRGNGQDHIDVVDDISSKWIAAEEAPAVVSEPMRRISSRSSAGSHSHKHRTLKAASQQKNRPTILSGVSHGSHMSSYDISGNGHMETYLLDSDAHSVSSQMYYPSLPMGVGMTSDGLPYSPEVIATGMPQQHMDPTHMQLDFEASLGNSPSASWASSFSPGEESRMSSPAIPEDSWTNAPLGTSPHAGTSSPVMDGQSPSGDGESSARDHPLYKNAMPKADGLFHCPWEGNSSCNHKAEKLKCNYDKFVDSHLKPYRCKVDSCENARFSSTACLLRHEREAHAMHGHGDKPYLCTYEGCDRAVPGCGFPRNWNLRDHMRRVHNDNGQSLSSGAPSSVSGRGSTSHSTKSRKRKSKDSTELSSHGRKPVSKTSAADDAAAAARAAEQPLIEQWYEHRSALQEYLQRYDNPVAFELLDQTGEAGEHFSSMEKISRKLKKSRESHRRAYHHHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X089</accession>
    <name>A0ABR1X089_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C6 transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671691.1">
        <property type="nucleotide sequence ID" value="XM_066808073.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041133"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919">
        <property type="entry name" value="PROTEIN CBG05606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="239" mass="26037" checksum="503C2323FE64C642" modified="2025-10-08" version="1">MVTTRSGAAAATPQRSTSSSSTTMAPTSKAAANNPAAAGVRWLHAPDRTTLFWFAVSLPLVIWDSIYVLGRPHTMEGGWLHWPLWAPYKLYGEVDHVYGWKSYNARNGFTAAQGALNVVETAMYLGYLWLWLTRAREVNVAARGGATKVLSGRPAAMAVLLAFTAAVMTVSKTVLYWLNEYYSGFDNIGHNSIQDLIPLWIIPNGAWLIFPSYMIYVMGNEIIEGLTAASSGGAGIKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0F0</accession>
    <name>A0ABR1X0F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003875</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[ribosomal protein uS12]-L-proline + 2-oxoglutarate + O2 = [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:54156"/>
            <dbReference type="Rhea" id="RHEA-COMP:13816"/>
            <dbReference type="Rhea" id="RHEA-COMP:13818"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:85428"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TPA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671808.1">
        <property type="nucleotide sequence ID" value="XM_066808190.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041250"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.20">
        <property type="entry name" value="Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019601">
        <property type="entry name" value="Oxoglutarate/Fe-dep_Oase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043044">
        <property type="entry name" value="TPA1/Ofd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039558">
        <property type="entry name" value="TPA1/OFD1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051842">
        <property type="entry name" value="uS12_prolyl_hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117:SF0">
        <property type="entry name" value="PROLYL 3-HYDROXYLASE OGFOD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13661">
        <property type="entry name" value="2OG-FeII_Oxy_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10637">
        <property type="entry name" value="Ofd1_CTDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="10">
        <location>
            <begin position="145"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="480"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="597"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="495"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="521"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="606"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="644"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="654" mass="73406" checksum="D2B7B9AE2F391F78" modified="2025-10-08" version="1">MKRKAEAQGAVQKPSKKKSKTSKPLSPEVVDARFRKGLLDDKVLQKYTDEYAKSSPYKHAVIHDLVDDKLLRAVRNEIKENVSFTPKETDIYKIHQSGDLANLDGLEDEALSKLPSLLALRDAMYSQQFRDYVSHITGCGPLSGKKTDLAINVYTPGSFLLCHDDVIGSRKVSFILYLVDPDIPWKPEWGGALRLFPVIDREGKDGQTAKTPAADVSKVIPPAWNQLSFFAVQPGESFHDVEEVYHTENAKQLKKQGGRVRMAISGWFHIPQPGEDGYIKGAEEKAAANSSLMQLQGNPDQYDTPQAQPVAIKQTDSSEEFNEDDLEFLLKYMAPTYLTPDTLEQIQEQFDEESSITLGDILGKKFGARLQEYVTAAEKEALPEDSSEIEKGQWKVAKPPHKHRFLYQGPSKSSAKSNKKAPKEKSPLQELLDDFLPSPQFRRWLQMATSSTIENHDFIARRFRRGKDYTLATGHEGKPRLEINLGITPTKGWGDEADEEEEETEAPAKSKGKAKGKDKKKGKEEEEPKEPEEVGGHEVYMAGDDDSAEDAAVYKSSGDDDNILFFQAAAWNKMTIVLRDSGTLKFVKYVSRNAPGDRWDISGTLDIEEQEDEEEEEDDDEEEKKKSEDPNAQIGEETEEEWNGFSSSAESESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0S3</accession>
    <name>A0ABR1X0S3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671900.1">
        <property type="nucleotide sequence ID" value="XM_066808282.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041342"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="92" mass="9855" checksum="FE1B9D4531B2A7BB" modified="2025-10-08" version="1">MRHEPGQRGLLTSFAPSVSPVTAHRTKRTISPGVYISKGEGHSVRHSWIIDGRLVEFPFAAATHIRDTYGHKTAGLGARPVPVGSLDGGRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0W7</accession>
    <name>A0ABR1X0W7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_003987</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671920.1">
        <property type="nucleotide sequence ID" value="XM_066808302.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041362"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06609">
        <property type="entry name" value="STKc_MST3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="289"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="331"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="487"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="352"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="373"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="447"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="527"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8089026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="666" mass="74219" checksum="1CA3B4A5E5A41D29" modified="2025-10-08" version="1">MADRDYDDNSNEALDPELLYTKEYCIGGGSFGKVYKGVEKRTGQAVAIKVIDIESAEDEVEDIIQEIAILSELQSPYVTKYYGSYAKGAELWIVMEFCSGGSCADLMKPGMIGEDYIAIIIRELLLGLEYLHADKKLHRDVKAANVLLGHNGQVKLADFGVSGQLSATMTKKNTFVGTPFWMAPEVIKQSGYDHKADIWSLGITALELANGEPPYADIHPMKVLFLIPKNHPPRLEGNFTKAFKDFVELCLQRDPKERPSARDLLKHTFIRRAKKTTYLTELIERHSRWSATHKSEDEEAMEGGDEVREREPVNEDMWDFGTVRLVGDRGGFVTRPSLNPMDDSARNARASRPLEGDYGERPRGQSPVKMQEFNGSSVSSTLKAANSPSTGTSRQVSPQRKPVPGSIPSSPTKVPLPSSPQKYYGDPDTPRPPNKHTSTVPTMNSTDYDHALQEQLRWDMGHMNITSPPSQPQLNYQQPDLALRQSHTQLYPPGPPSQRVPSKVGPLSLPEIPPFRGPASQSSLHKPAMQQPAFPSPQAFPSKAQPKQLPAAPESFPTPAPPNPNGELDALNDVIFPALEEALKRRQIRLQQIYRNERVTPQRQRAEAAHDKIRKHVYKLANVCKEIDRLDKSEPVGMGKEVGTFLEGLLEEILVRVEPLDEEELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X221</accession>
    <name>A0ABR1X221_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-mannosidase</fullName>
            <ecNumber evidence="3">3.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004429</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.24" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672362.1">
        <property type="nucleotide sequence ID" value="XM_066808744.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041804"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="entry name" value="Glycoside hydrolase 38, N terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.50">
        <property type="entry name" value="Glycoside hydrolase family 38, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054723">
        <property type="entry name" value="Ams1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041147">
        <property type="entry name" value="GH38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011682">
        <property type="entry name" value="Glyco_hydro_38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015341">
        <property type="entry name" value="Glyco_hydro_38_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037094">
        <property type="entry name" value="Glyco_hydro_38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000602">
        <property type="entry name" value="Glyco_hydro_38_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46017">
        <property type="entry name" value="ALPHA-MANNOSIDASE 2C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46017:SF1">
        <property type="entry name" value="ALPHA-MANNOSIDASE 2C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09261">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22907">
        <property type="entry name" value="Ams1-like_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17677">
        <property type="entry name" value="Glyco_hydro38C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07748">
        <property type="entry name" value="Glyco_hydro_38C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01074">
        <property type="entry name" value="Glyco_hydro_38N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00872">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="Families 57/38 glycoside transferase middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 38 central" evidence="7">
        <location>
            <begin position="536"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1061" mass="120381" checksum="2065860327640C5B" modified="2025-10-08" version="1">MCDHADNPYDILPSILNLRATIMGGERTQPTKATASVANYPMQAAGPVGKRISNIYKERITQFYSIGQWEKQNLLAMMYEGIASGHPHVKLSTWAAPGLSRPTFEEAMKGDFKSTNVGESFGPSWATHWFKIVIKVPSELCDKAHLEFQWDAGNEGMRVEWILPKSFRNGQEHTFYIEMACNHMFGNAPGGDSIQPPDPNKQFRLVKADICAVNMDARQLWIDTWIIGDAAREFPEDSWEQHKALNVATAILENYKLGDKESIKKCRKIAQDYIGANVDSAKVYDSGKEAQVFGIGHCHIDTCWLWPWAETKRKVARSWSNQCDLMERYPELNFACSQAQQYQWLEEYYPYVFDRVKHKVKEGKFHPIGGSWVEHDTNMPSGESLVRQFLYGQRYFESHFGERCKTFWLPDTFGYSSQLPQLCRLAGMHRFLTQKLSWNNINNFPTLPSTGWRWTAASQHKSMDQDHTSLLVFGKGDGGGGPTWQHIEKLRRCRGISDEVGLLPRVHLGNTVDQFFDKLQDKGTSLVTWYGELYFELHRGTYTTQANNKLNNRRSEVLMKDLELLATIASLQDKSYQYPKKDFDKMWEAILLCQFHDCLPGSSIEMCYDDSDELYAEVAKIGERIFKDICNLFKVSEMKPASVGDAVALSTLPWHRKEVVDISETQCGVACGSGPMLSIKNFKTDGEKAVTVEEVEKGVFVMQNEQLRVTVEKGCITSLFDRQAGREVVAKDGKANQFVIFDDKPLYWQAWDVEVYHLDSRQELACGPTKIYEDKEHRVGVITETKISENSSMKTVISLSAAFKGQQSFVDVTCDVDWHETMKFLKVEFPVDITNTEASYETQYGLVRRPTHYNTTWDMAKFEVCCHKFADLSENGYGVSILNDSKYGFATCGNLMRLSLLRAPKAPDAHADMGRHTIKWAILPHQGSLGATTVRAGHNFNNPLKVLSAPTSDSMKTMLSSHPVQLTGDSSLVLDCVKRGEDDEGVSRGELQKRKGQSVICRVYDSLGGQSRGTIKSTWDVKKVWKTNVLEDDEEELDLDKNGSFSIKLRPFEVATYRLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X236</accession>
    <name>A0ABR1X236_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_004363</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672296.1">
        <property type="nucleotide sequence ID" value="XM_066808678.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041738"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF10">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045870013" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="16">
        <location>
            <begin position="17"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="17">
        <location>
            <begin position="51"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8089402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="198" mass="21072" checksum="2246843F6761A212" modified="2025-10-08" version="1">MKVITALGLLVAAANAHYTFPGLIYNGKTEADWSFVRETTNKYSHGPVQDAVKAGDTVGFRVDSDLGHPGPLQFYMAKAPLGRHGRIYQDGPSFAGGQVTWPSAGKKEVSVQIPKCLPDGYYLLRVEHIALHSAGSVGGAQFYIGCAQLHVTGGTGTVTPSGVSFPGAYKATDPGILFQLYWPVPTSYTNPGPRPMTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2C8</accession>
    <name>A0ABR1X2C8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672467.1">
        <property type="nucleotide sequence ID" value="XM_066808849.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041909"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="495" mass="55242" checksum="B7696E30CD984494" modified="2025-10-08" version="1">MNQQGLTQTLIDSFSALANEVQNLTDRQTILEHKLRYAHEQYQQLADRYAPASTEISETLVKLQLPPELENSALANTNPVPLPKRKPSDSKHQIALLIREGRRVASSLTELSRSSHSSRDDSLPPTTMTSMSTILEQDFTIEGKKKGLLDCPFSRPISEEADVQHDAQDGSQQANVDSTPHQSSDPICAAMYEETGSQHATSAQGGASKCPIRYMDQHSPEEIAHYLETHKHELPRSHEVCVRRYQKNEEHIRKLDAKYGSLVHMVEGLSRIHQPMLPEQDTRPQSDVERTSDDRVQTWAETVSAITDDPDRTALEDHSSVEEDRQSHFDRPLKEVRVGESPSRPWGISVPIYDTLSQRGDGPERPESPPPAPVHMPSPVPNPETPGKKTGKCPFDHTKMKMNGLTPPPPMRTPEDKCSDRLDGPPSNLPFSPATQTHAPPPMTTPGQPTFLDAKQFARPAPANTPQMIFTGPVFIGYPMEQAVQFMQHFQGQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2R8</accession>
    <name>A0ABR1X2R8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672603.1">
        <property type="nucleotide sequence ID" value="XM_066808985.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042045"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846:SF1">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="134" mass="15524" checksum="689B43CAA728AE5C" modified="2025-10-08" version="1">MAKKHKKPSQPVYNGGVNISLGAGEATRSKSLQIVKRWDDYFQGDALGNWQRLMKDLGFQEEFRSKTQCRNALKKVWINIYDFLDAVKAGKPVYQFKTEVELSHYTKKTGRVYPKKHIQKGSPLARLMAHIFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3X3</accession>
    <name>A0ABR1X3X3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_005071</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673004.1">
        <property type="nucleotide sequence ID" value="XM_066809386.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042446"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 12" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8090110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="183" mass="20943" checksum="CA88EC68294B7B46" modified="2025-10-08" version="1">MGLNISKLFDKLWGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRIVEAREELQRMLNEDELRDAILLVFANKQDLPNAMNAAEITDKLGLHSLRQRAWYIQSTCATSGDGLYEGLEWLATTLRKAGHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4A9</accession>
    <name>A0ABR1X4A9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673129.1">
        <property type="nucleotide sequence ID" value="XM_066809511.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042571"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="95" mass="10581" checksum="7CF12532E44A0979" modified="2025-10-08" version="1">MIPRSHNIQAGTSRRRRARERTSAEHLVQIAAPSHGTIVVQGPAQGEDWAGDFSAYCQTGSPTEPAPRHDDGFLSCVYNIRIRAWTKQDDKKQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4Y9</accession>
    <name>A0ABR1X4Y9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromatin target of PRMT1 protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673351.1">
        <property type="nucleotide sequence ID" value="XM_066809733.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042793"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="8763" checksum="B3ACE4B6F44C8FE5" modified="2025-10-08" version="1">MTNNVSGKAKTRYGAGNNAAKPTAASGGRNALSTLDGNTAGRQKTQKGKENKVLRQLDQDMDDYWAHGPVKEDKDIKVEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
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    <name>A0ABR1X824_9PEZI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673579.1">
        <property type="nucleotide sequence ID" value="XM_066806283.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039343"/>
    <dbReference type="Proteomes" id="UP001433268">
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    </dbReference>
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        </location>
    </feature>
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            <begin position="226"/>
            <end position="250"/>
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    </feature>
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        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="278" mass="31548" checksum="15E69AEF67127BC7" modified="2025-10-08" version="1">MCEKHYYYSQRGNQLHEERETRGGAPTSSPPSPPLSDTGYVYSGSEGSHKRRSGSYYPTGSNVVEVGRKPSQRRRSVVVEDAYRPVTPPTYYSTSPSRAEYSSPPRRPGVHIEISSNTRDTRRSSSHHRGSSSTSKTSSRAGTVGSNASSEGERLAKLEREMAKTKEALRRQQVKSKIERQNEAIASRPAVPPAPKPYRRGSVSVRPPVDQLSDAMKHVRIGNQTAAELERERRRTERRVQEDLAQREEAAQRERLLARMERRNSTAVYDDTRYRRQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X993</accession>
    <name>A0ABR1X993_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673999.1">
        <property type="nucleotide sequence ID" value="XM_066806703.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039763"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
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        <location>
            <begin position="19"/>
            <end position="370"/>
        </location>
    </feature>
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        <location>
            <begin position="339"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8092027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="370" mass="42285" checksum="8C2BDA6530B88D92" modified="2025-10-08" version="1">MIASRLFLWGLGVQTLLASPSRDPDMDLTEEIMQLLLGPKNEGIRGQIREDALARGNTPTSRPRLVATEETIEFGDTLWIVDRVLEPQTIIHFFEFTWNGRLPNGKYTELPLLGDDMELVTEPYSEWAPAPFDKHPEPAAVEIMARIGSGHDSGRLQIISKDLHAMKSRLWEGIMPLSQRRLDERGANDLRNFTYTSQLVTQIINVFHYLNEPDVRYALRDTYNLIYDHLETFEKALNAKRAQESLPSISVTALWAEYMRSQYEVIENRAHTWVLQVLRPLKKKVLAALRGHQQDQLMVAEYDEIQWKLTNMWQDLSENTAHADWGIFIPMDGYKGCTSPSATPVTSPPRRTLPLMARSQSPSRQTQTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9J0</accession>
    <name>A0ABR1X9J0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">PG997_000010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
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            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674098.1">
        <property type="nucleotide sequence ID" value="XM_066804325.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037385"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="103" mass="10975" checksum="00B3FA7E8EE43B5B" modified="2025-10-08" version="1">MKAVRLLDPGSLVPRKGQGVGVEGQEKGGEEELVHLGRRSTDMNGILEETRLELVSGRWLSPKKPLARVVRGICHGVMRAFACDPPRGPAHAAVESSSSPPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9X0</accession>
    <name>A0ABR1X9X0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT-NTPase and P-loop NTPases N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674231.1">
        <property type="nucleotide sequence ID" value="XM_066804458.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037518"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031352">
        <property type="entry name" value="SesA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17107">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="12"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="24323" checksum="1BC48775B17D5248" modified="2025-10-08" version="1">MEPATALGVAAAATQFFDIARNLVKQYQDSRQPPVSQAAFKKAAVDLQKLSSTFKERPEPPRDNTNSVHEHQKALDKLIVDCDKTTEELIDLLNRVQPEEKGSAWASIGQAIASVWNADKIKSLEERVGTYQNELTLRLLAYMEAKQGSTSFDDDDSLPELMRSDSRIMDMIHTSNTDTLDEAKERHSSVLSRLPFVGNQRSSSMPEVNQRAAGEEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBX9</accession>
    <name>A0ABR1XBX9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000890</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674978.1">
        <property type="nucleotide sequence ID" value="XM_066805205.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038265"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="348" mass="39549" checksum="3B963A159FA57795" modified="2025-10-08" version="1">MGWVEHVAGPTLVLSLLSSLATGLVLMIWLSSAAKPMVKGSSREERAARGARPQFDDIRAALQSEWLDRPGYSPGIRFLYIRHSPGDSLYLQLPHLADASLQARKVWTEGANYHGVSGTIALALNEMEPASGNWCWIAGDPPYLRYVLGHCWRFAIFVIIIGIYLYIFIKVMLRVRTRKRTNSRSAQLGRPKIREISWPSATIQSAKDLEFQLSSFESSVETPSREEFAIRPSNTRTNSQRSAAGTDNNRHHHFDTELRHWLVLSIYPLTYMLVWIPGLANRLVELQGDRSQLLSVLQATTQLTGFINALCYGFKELHGRVQKKQNVNRSLDEHNNQRWGFTVYRELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC22</accession>
    <name>A0ABR1XC22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alkyl transferase</fullName>
            <ecNumber evidence="3">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000871</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674959.1">
        <property type="nucleotide sequence ID" value="XM_066805186.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038246"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="189"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="352" mass="39855" checksum="6CBC884858CEFFBD" modified="2025-10-08" version="1">MSIKADANVQRWIATLPPIAWALRQARETLIGTLRQGPIPQHVAFEMDGNRRFAKNNHIETIEGHNMGFEALAKVLEVCYKCGVKVVTVYAFSIENFNRPKSEVGGLMKMAKLKLEQLCQHGELLDRYGAGIRVLGERDLIPDDVLPFVDRAIEMTKHNTDAVLNICFPYTSRAEMTAAIKATVDEFSIPSEPPATPFSQARITETIRSKQPKRTDSSTSLREASPDPAAKSDVDDSVSSTTTLNPGSPRTEAKGKEKAIPFKDAESITVDSINSHMYTADCPPLDIFIRTSNVMRLSDFMLWQCHEDTHIFFLKCFWPEMDLWHFIPVLLEWQWRQKKEREGTSGRRLKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCI0</accession>
    <name>A0ABR1XCI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000994</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675082.1">
        <property type="nucleotide sequence ID" value="XM_066805309.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038369"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016278">
        <property type="entry name" value="DUSP12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848:SF4">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000941">
        <property type="entry name" value="DUSP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="358" mass="39815" checksum="1466B00F7D76EF01" modified="2025-10-08" version="1">MALDRIPGKDNLYVGGIFALRKPDGLHGKNINHVLSVIKYSFEGWGEEAKQFQHMSIDVDDMDDQDLLVHFSSAVRFIDRGLYPPESTSGDQHQDTETSPGSVFVHCAMGKSRSVSCAIAYLLYKYPHRYGGKQFDASAISTAQRRETATDAVALALKGIKEARPVAEPNSGFMQQLELWWEMGCPADSDGAVESHPIYQKWLYERRLEESRAAHMAPEPEWIRFEDEAPAAAVPAASNDEHKELKCKMCRRVLANSKFIIDHNGTGNETKKSVPCGHIFVETLSWMRPALEDGALEGRLNCPNPKCTAQVGRFAWQGLRCSCREWVCPAFSLKPSAVDESNRSAGSAIRMPPRSGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDV3</accession>
    <name>A0ABR1XDV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450 monooxygenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675603.1">
        <property type="nucleotide sequence ID" value="XM_066805830.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038890"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="199" mass="21645" checksum="2DBCEB455D2E0DE8" modified="2025-10-08" version="1">MRHKRIIGPCFNERISVLVWEETTRQVQELLDKKIFARADRTHTTLCDDSRTIALHAFMGVGLGAPQDFSTGARQKAGGRRFSFRDALTSVLHELILTTVASQLPPAVLGLLPRYISEKKVAFDEAGLYINDLIRAQEEVDSDGLGAKAPAASSLSSEKKKPSTFLSTLVSNARDDANTAIEDTTATAGAAKRGSRSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE05</accession>
    <name>A0ABR1XE05_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ww domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675619.1">
        <property type="nucleotide sequence ID" value="XM_066805846.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038906"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="417" mass="42971" checksum="3C0E62D86A95819B" modified="2025-10-08" version="1">MAGPASPGTEGPTYEPPSLPPGWIAQWDGSSKKYYFVSISTGVSQWETPSQAAPGGTPAPRGDHPYGAPGAHPELITHPDGTQTIKHPDGRMEPVLPPEGARALESGPTGERGFGSFATNALMNQLSASQFLGGGHGNNNNSGHGNTSGGQGSGGGPAGKLVGALASSLFSSGGSGKPEQPQNYHGGQSHQPAQSGGFAGSVMGGVANMFGGNNQGHSSQNFGYSNTGSQGGYSGQAPPASYQPSSASTPAYSSSTTGQHTSQHGGAPSYGAQQHQQPQPHHTPSFPPPQHTSSYSSPPPNTQSHVPAYGSHPQAQAPGYGHSPVSQGPHYSHQPPYNTSPSGQHHQYNGGGHQQYPLPSQLTTPNTDRYLRHLAPILDPRHTPVETSMHPRYRAVPIPTMASNQVKGVTLVTGSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE32</accession>
    <name>A0ABR1XE32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675716.1">
        <property type="nucleotide sequence ID" value="XM_066805943.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039003"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="39294" checksum="03F39DAED0DFA1A9" modified="2025-10-08" version="1">MMAVYANGYINISADSAGDGNGGLFRQRDPAMFQSFLVPSDRTGSNGSYNCHLSNWDKYVESAPLKARSWVTQERFMSPRVVHFSNDQVHWECVELMTSESVNSSFHIGPEFIWTPEKSFHAFIQEPNSDTKIESLYTIWYRLVESYTTGQLTFISDRPVAIAGLARTFAHLLQLEQKDYICGLWRPYLVLEMMWYTFTSTDRPNPDIPSWSWLSVNGDVWFKTPQVATKYQPVAEVMDVRITASLGDPYGSIVSGPLKIRAPICRAKIRRVPDPHARLDDGPKWEYTFVLGQEEIGEGHSFMLNLDECSSEFMEKVLSQDVYLLLGQGSILPYPETPDLPGSKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEG3</accession>
    <name>A0ABR1XEG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675782.1">
        <property type="nucleotide sequence ID" value="XM_066806009.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039069"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047324997" description="Cell wall protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8095009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="22371" checksum="CEEF5DC8105AAEC1" modified="2025-10-08" version="1">MKCSILPLALLASLRAVSARTSIDKRTTSTTLPAAMSDVLAAARTLDHVVGAYAGGEAEDVECAINTAVVVLRHATQLANDLPAGPMGAEDAAAFKASSESLAHAGEGLVSCFAAKIPAFNEARICNSVTTHVTDLDDGVTALYKAVGSKLPAGSEAMVADTHKPFGDLKDSMGDCSACGLLDDAPRLRPFPGPVGTNGASAATVSCGAMFVAAGVVAFFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT90</accession>
    <name>A0ABR1UT90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660473.1">
        <property type="nucleotide sequence ID" value="XM_066819588.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052648"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="16"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="345" mass="36055" checksum="B9652261B82489C0" modified="2025-10-08" version="1">MRAWTVTQTGLALDPHRPAPSLATAAAAAVTGNDLLLRVRYAGLNPADLALMATIPSWLPWRRNPIAGLDFVGEVLAAGPSTPASVAKPGTLVCGALGVRQVFFGAGTLAEVLVVPADLVAAVPQSLLGEPRAAVGLGVTGQTAALVLREAEAEGVGRVRRWKGVRVLVNGASGGVGSVLVQVLKARGAYVVGVCSGGECGDVTQVIDYTSHRDLYGYIAESAQDHSLDLVVDCVGDSDLYTRSPGYLRPDGRFLSIVGGPSQGIYPFLMHQIRPVILGGTPRSYKILGMGPSGTGAREVAGWIEKGDLKEVIVDSEFTMDEVTTAYERVASKRAKGKVVVRMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU53</accession>
    <name>A0ABR1UU53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014524</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661026.1">
        <property type="nucleotide sequence ID" value="XM_066818838.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051898"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF21">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="29"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="292" mass="31940" checksum="9848D10534D224AB" modified="2025-10-08" version="1">MVNVAGDGVPLLYLTIVFLVLSWFIFVTRVGVRRWIHGFGTDDWLMGGGLALYTVTASLVIVCCFYGAGQYSSALAAGDVQTGTKLFFIAEFFYAACTVLVKCSISVTLLRIADARRRFVWTLCAVMGLTAVAAVIFIIVIANICHPITMLWGETTEGSCNPSLNSTVSFLFSAASIVTDLVLGILPGILLWNIRMKKTVKLSVIVILGMAALLRYLTLYDDQNEFMFSTGAIGLWSILEEGIGIIAGSLPALRPLLSLRAFWRQWSRNRSLIDKRPKPPAWRSHSSATATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU54</accession>
    <name>A0ABR1UU54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cofactor FMO1 FAD enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014553</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661055.1">
        <property type="nucleotide sequence ID" value="XM_066818867.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051927"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="13"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="585"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="630" mass="70054" checksum="F69F0E45C5B2667E" modified="2025-10-08" version="1">MEYTSDSDVERVDVVVVGAGWNGLISAKTYLDFKPSASLVIIDDNATFGGVWSAEKIYPSLYAQIKHGLFEYSFYPMRNEGITEDGYISGQTIHQYLNDFAWDFDLVRRSRLQTIVTHVSRTVWGGWRLDLGGKAPIECTKLIYASGATSHPVIPGWPNKGFRSPIIHSTEIGTHLKALENIESATIVGGAKSSYDTVFLLLKAGKKVDWIIREDGSGPLAIMPPTLLGMANTMDVVTTRFVALMGCSIMNTDGAAQDFIQRTYLGQCIAWLFWAAVNWIAERHAGYSQSENAEKLRPEPHGNGIFWANAGLGAASVPLFWKTFHEGNCRVHRTDIHSLDDRDTVTLKNGTSYQTDYMVLCTGFDKSFHVFSEQMQEDCGFIANPAEGTKWSKLERDAEKVVDELLPAIKTSPFGLSNTFTREETADGRKLLHGPSRHYRRLVVPSLAAQGDRSVFFPGFIHTIYTPIVSEVQALWGVAFLLGLHDTPPLEEMEREVAGWTVWSRKRYVSQGKKHAYAIYDFLPYIDTLLRDLGVNPQRKKSYLASLFSPAYPREYKGIADEFRRAVAKERSLILAARGTPGTATAELMGKGEASGAPDGRLHEPASAKKVGVPGAICCLRNPRRRPHMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUM1</accession>
    <name>A0ABR1UUM1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661225.1">
        <property type="nucleotide sequence ID" value="XM_066819037.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052097"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="74"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="362" mass="40035" checksum="899B6B0131249091" modified="2025-10-08" version="1">MSVDIAKEMPANPRDWTGGIESYLEEHQIVCEKVTPLTSGLSSWVWRLDGLSDGRYREGEPAILKCAEGMAKLAPVPLAADRLQLEIKALKSRAVAEACRQEPSVRVPRVLQETQRGYLMTWGGEMDLRVAYKEGKLMDPAAVGARLGKWLACLHLAGTDRDEWNTRNSDVDTFIAPGGLEEQAIRTALGTEGSSVQEIDHVIDVLRQPAPVQTLTPWDFRPMNTLLKFKEPGAVPELTIVDWEFSHYGDPAYDLRLWAAEAMVLEAKFGKGKENSGSLLSSCLAAYRLGTGDAIVDDKFVCKTAIALGAFLLLFMPAPFWDCVEEDREPWVKLALQYIKAGAETDMGWLLQSSLGPLLMKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVY7</accession>
    <name>A0ABR1UVY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">TFIID subunit TAF5 NTD2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_014307</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat TAF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660809.1">
        <property type="nucleotide sequence ID" value="XM_066818621.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051681"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08044">
        <property type="entry name" value="TAF5_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007582">
        <property type="entry name" value="TFIID_NTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04494">
        <property type="entry name" value="TFIID_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TFIID subunit TAF5 NTD2" evidence="10">
        <location>
            <begin position="69"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="360"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="476"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="518"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="562"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="612"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="655"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="656"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8062210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="736" mass="81424" checksum="3624BC02C47906A7" modified="2025-10-08" version="1">MNALIPPYPEPLPAGRGRSEHVYYEIGKLSPQEVTDYLLKRGYTHTEAVFRKEVQNVDPSGRPLKNNDEMGPKKYMRAYTHLEKWVENSLDLYKFELGKILWPIFVYSYLELVEGNDLGEAKEFMEKLHERFENVHRDEVKSLQLITLPAHVKENAMAKLYRENKYNIPLNKFVVGTLMTFLEKDEEQGGACLRFLLNNYCKIDAVSRGPIEPFSFEAIYRRARNMELDDVDAQEGIPGAGTKTGVSNRDILNNKAALKLGPLPMDAELRTDVLSELEEEDKINPPRDGTSTLVDEFNLLHPIKKESADSPQRTDIPYPPSRARDVVMEVQKVRENRDRFRIEGRTGGVGPSVSVCMYTLHNTLGNVSSMDFSKDQELVAVGTTDSYIRVWSMDGKPLTSTLPTEKDLKVNNRKLIGHSGPVYSVAFSDAIANLDRNIYEGDGPKPETNSKLLISCSADGQIRLWSLEVWSCLCIYRGHDGPVMSLSWGPHGHYFASGGWDKTVRVWSQDHASAQRLLVGHDTSISTLTWHPNGAYVFSASDESDKSIRMWSVNDGKCVRVLTGHAEYISCLECSPNGKILASADIGGNIFLWDIEKAVRIKRCRGHGRGGIWSMSFSVESNVLVSGGHDNTVRVWDVEMPPEGVKAAAQTDGVDGAANAANGGAESSNKTSGSNAQGSGSGAGASGGTGKKKGKEVTITPDQISAFPTKRTPVKKVVFTRMNLVIAGGCYEPELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UW70</accession>
    <name>A0ABR1UW70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660688.1">
        <property type="nucleotide sequence ID" value="XM_066818500.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051560"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF20">
        <property type="entry name" value="AMIDOHYDROLASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase 3" evidence="1">
        <location>
            <begin position="63"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="558" mass="60584" checksum="90A571CD86D24739" modified="2025-10-08" version="1">MGLSPVSAVLHNGRFFTSQGTNGRAHAFTECLVIDATGTIAHVGSLTDPEVARAEAAGAVRHDMQGRVVLPGFVEGHMHLLRLGQSLQNVALDDCKNLQEIRDTIKRYARENPEVPRICCKGWMYAMLTEGEEASTGLLDDLDPRPIYIDEKSLHSTWCNTAAVKEMGLQDMPDPQGGKIHRDASGNPTGVLAESAVMLVVWPHLAKVASMEEKLSALQGAIASYTSEGYTGAVDMAFDENMLEAVRVLRKLQKGKLPIRLAAHWLITPRATEAENLAQVDRAVKLWREFKGESDFRIAGIKIICDGIVDACTAALTEPYSSTGTNSELLWTIEDIVPVVRKADQAGLQCALHAIGDLAVRTAIDALKQAATPNADKRHRIEHLEMTSPEDAARLGKLGITASVQPVHADPAILKAWPRLLGEERCGRAFAYKEFAEGGAVLALGCDAPTAPHAALKNIYTAATRRSARDPAVTEEDGDKDAVRMMNPQFALELAAAVTAATAGSAYSCFMDRWAGRLEKGLSADLAVVEMEWEAEKLLEARVRETWFRGVKVYEAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1Z4</accession>
    <name>A0ABR1V1Z4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661958.1">
        <property type="nucleotide sequence ID" value="XM_066816266.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049326"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046813461" evidence="1">
        <location>
            <begin position="19"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="9803" checksum="A622EC7D4BAED630" modified="2025-10-08" version="1">MHFTALFLALVAAALTAALPTSKDYGDEYPDPPRKMRLSLSFFPHGPPKDEQEEWLDGCEEVCVDDLGISSKTCSMLCQSALLKAILDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V278</accession>
    <name>A0ABR1V278_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662051.1">
        <property type="nucleotide sequence ID" value="XM_066816359.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049419"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="351" mass="39598" checksum="D4F0C7F5E5EC8468" modified="2025-10-08" version="1">MSNETVGSLLAVIANSLNDALRIMMFADKRAWGPDEFEQLRLLEDTLDEAKRDFQELPLLVKGRVYYEHDRKPESLDDLRELCSQFELHTKLFKDWAKMGGPINPVWATETISLRRELHRAQCRAARRIFNSEQETSVRCLGAFQVYRVQRTPDNPQQRQLEELMTCNEVGKFERYGDLDLAFICDFCDGYLVWEDLREMPTRRTTKQDTTNGGGGNGNENDNNNNDDSGSGSVSGSIGATEATSSTAMAPGAQDTWHAQGFKRSDGEEKAVVFAPVAIANHLPTEPGDFQARILCPYCEDYVGYEQGDGEMEAVKWNQDERGFDDVISFQEHLEWSHADKAPAQSTCAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3M0</accession>
    <name>A0ABR1V3M0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1688-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662538.1">
        <property type="nucleotide sequence ID" value="XM_066816846.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049906"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012469">
        <property type="entry name" value="DUF1688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687:SF3">
        <property type="entry name" value="PROTEIN URG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07958">
        <property type="entry name" value="DUF1688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="47601" checksum="ABD14A458B99D927" modified="2025-10-08" version="1">MNTSEDKDISYLLSLQAVRDRSRLVLKAAGEGALNNFDYHPEHMPKTADFVLSVISRDFGPDRYTEIPPHGRWQHFDVGGVDRITPLLKKWESEGCDPTERTRRLIDLFFVSVLLDAGAGDVWNFKEPTSGKTYGRSEGIAVASLYMFTAGVFSTAEGPKECVDGAGLTGLQEDVFNSYFQISSENPMVGVSSRVNLLNNVGSSLLSLPKIFGPTGRPGNLVDFLTQSSKEPQVLDYEVLWSALQNVLIPSWPKNRTHVRGTPIGDAWPLQVLADRNQGDKELGAIQPFHKLTQWLGYSLTVPFVRVLGFRVVNAELGTGLPEYRNGGLFVDLGVLQLKPAILEQGRNASGQDLPSYSATGDVIVEWRAMTVALLDELYKHVSAHFAEKGVQFSMAQMLEAGTWKGGREMAALHRPQTRSSPILMDGDGTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3S4</accession>
    <name>A0ABR1V3S4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011718</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8064971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661725.1">
        <property type="nucleotide sequence ID" value="XM_066816033.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049093"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051143">
        <property type="entry name" value="TrkH_K-transport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064">
        <property type="entry name" value="POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064:SF37">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="9">
        <location>
            <begin position="869"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="196"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8064971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1226" mass="137206" checksum="17A97C77E4DB686E" modified="2025-10-08" version="1">MSQDPESTGSVDHPQPSRYAVLRDDWAEKWRVVRPYLPPVNFITVHHAYFIFVSLIAAAVFYAIASAESTFTVSFVDSWFLITSAFTASGLNTVNLSALATGQQVVLFIMLILGSPVLVSLFTIWFRYHIFEKRFDHIVEMEREKRRRKRATGTMVGMAGAMFGLPVMSSFGASANKTHAQRAAEDAFELSKPRIPSWPRWKRRPDPPATAGRRGPMSGPADSRASAIRTTPTKAPPPPPASSDQFNFHTFLHENRKSIGRNGQFFDLDDEQREYLGGVEYRALKLLFVIVAVYFVLFQALGALTLGAWLAVHSRDVTAVNAQGPWWSGIFLAISSFNNAGLTLLDAGIAAFADDAFVLTIVTILSLAGAAAFPACIRGIIFLCRLVMKRWIPQAANRAAQQDYEDWLEAFDFILKYPRRLFMLMFPSKANFVFVAFFSSLVTVDWILLLVLSIGNPVLEAFPVASRVGIALFQACTVPSGGFAVFSISGLWFDLQVLLLIIMYLAAYPEIIVMRNSNVYEERSLGLYSSEEAEKQEEEEDAASLNEMVESARSPLLSPTSHRFDTMSHATGASTKSIKMLSAVGRRGTAFVGRQIQKRMNDFQGVGVDTGRVRRPSHPTLKRAQHIPFENLNGPTAPTATPEGGISLVSQHLRGQLSHDMWSIAAALFLVTLIETSHSIADPRTFSVFNFLFEIVSGYTNIGISVGLPDQSYSFSGGWYQGSKVVLILMMIRGRHRGLPVALDHSVKLPGWDNQKHEDEDAEIRRSLSRGRLRGRGCRGDRYSSRPVAVQLAYQVGDQGWNWQKLDLICFDSAFFSGRFNTDLPLRWLHHCESHHDCGTVHGAPLADGVTLIDCQERCTVPKDGPETYVALSYVWGKTDRRTQLPSRLPRTVEDAMQVTRMLGFRYLWVDAYCIDESTRQEQVDQMDAIYGRAHLTLIAAAGEDAESGLPGVCSPYGEPCLVQEKLGLVQSRAMKPWASINTSRWATRGWTYQEAVLSRRRLVFTQNHVYFECRNMSCWRAKHLHTPGLRPDIDDLENECRLNQEGFAIWQSEDRSGEVDPKYYGIDVGRRAGFPSWSWAGWSGEAVGLFWRGPACEEDMRVVEVKEGALGPNSMLQVSTLFIKTTTFPKGRVVFCSGTSAIRPVLRRQEIFEDEESGYRLALALTNCGKEDQDAALVLVLQWMPEKHSYARVALGLLVHDADQQHTTFIRRLVEGQERQAIFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4F3</accession>
    <name>A0ABR1V4F3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-dependent monooxygenase terC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011943</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661950.1">
        <property type="nucleotide sequence ID" value="XM_066816258.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049318"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050631">
        <property type="entry name" value="PheA/TfdB_FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43476">
        <property type="entry name" value="3-(3-HYDROXY-PHENYL)PROPIONATE/3-HYDROXYCINNAMIC ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43476:SF4">
        <property type="entry name" value="BLR0106 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="12"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="409" mass="45350" checksum="DE47F7440C5E1DF0" modified="2025-10-08" version="1">MRVSPARPPGLVIVVGAGPSGLLLSLLLAQHGIPVHILEGASELDGRPRAAIYGPAAIPDLARAGVLDEIRRRGFTVNTMSWRRFADHSFITGMDGRCVADVDGQDLRMACLVLDELDRLLLEEFLTKHGGSISWNHRVVAGAWAEVETPEGRKKVQADYIVGCDGATSMVRKSLFPDFPGFTWDRQIVATNVYYDFEGTHGFTNTNFILHPEHFCMVAKITRNGLYRVTYGEAGGLTLDQIKERQPMKFETILPGHPKPGDYKLVSLAPYKMHQRCAPSFRVGRVLLAADAAHLCNPWGGMGITGGFVDAGGLADCLIGLWDGLADESILDLYSEKRRDKWQNLIDPASQANFLRVSDPDPDTLLERDDVMRACKAAENDEGMQREAFMGMMELRYDFTQHYNKKPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5E6</accession>
    <name>A0ABR1V5E6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentatricopeptide repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662023.1">
        <property type="nucleotide sequence ID" value="XM_066816331.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049391"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="870" mass="99816" checksum="3F4CBDCB5A94A613" modified="2025-10-08" version="1">MRSANRTLRDVKLRRPVPSLQPTRHRTLPSRLAQPVCRHHDALSTPWKRCVATAPATLDMTLLEPFPMPSDRLSSRNPAANDTNGLLQQSASFGKWQWLSLKPGRLAIESDFSRTGPARKYHLPLQVDNLENQNDFGLWYCLLDYLQRHHGDEGVHRLWKGMWGRKALYSTDKTSSLVFWQTILETALRYDNEQFLENILVYAEWMKEIHNNEWPNLYMGILSHYLRSHQHSKALQWHLRLTPNFQPSSSEFTGLIKQFCTDKVLNESGTLPRLYTISHERHVYDAVVPYLYALGSSQLARLWHKTCLNAGDGPTLYAPAKPFLRYFAGYYPESRQHWSEQEQAAMDTLDQHSSSQQNADENENGDFEQLEVSREFMNRVHGSTFGFTSKSYNDKLGARWFASSWVSLDTAISVVSALGIQQIGPLSLQSIALRDPSPEGVLRRIGHLRDLGIVLPETNYVKSIQYLAKIHDEELLLDLLQCDLHPDVFDDIELHSKLMDSSRASGDLRTYNLLLATRLATYASSNHASANTMLAVSLTMEDHGNIIRVLGDMFHWKISVEPEHVEKLFELMQANAPMHPSEGIKQDDPRRSFKILPSPDDVRFCQALLWTLRRMDVPIPARINKQLIISLGRQGKMQLLLPVMRDLINYYTKRQSARPGFIPVAVCDLPKAMTRPLGGVPKLLGVYIPIDTPAERPHHPLSQIFTPRVVASLIRWSFRKIPDGNTKAPLLQLQKKRLSPGFEFVRVIAVLRTLKDVGMNMDASTIRKAIILRLAELYGGVEPMKKSTKSVRRRNRLSLIQAKRMCDDAWGMTKDNRSFPASKSCNGKSKKLDVYNENWNDELWMRIEERVRRKQMLQRKRSGHHDNVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6H0</accession>
    <name>A0ABR1V6H0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662382.1">
        <property type="nucleotide sequence ID" value="XM_066816690.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049750"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052220">
        <property type="entry name" value="METTL25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12496">
        <property type="entry name" value="CGI-41 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12496:SF0">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="126"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="576" mass="65513" checksum="D541E4E6D5D294EE" modified="2025-10-08" version="1">MKPATPLPYPDCWASPEEYVESLLEFATTSAIFGTLCGGVHILDFFTNEPGLFQAIVPEDWQAYLVRIEPMRLLDVLMREDLDLLGEDERPPESLVQYIKDVRRFSLARDFVHQEKLPKLTRQVAIHEVSNFASYISGLADEFTDISGEDITHFVDFGSGQNYLGRALASAPYNKHIVAVEGREHNISGAKALDTLAGLAEKQKVMRNKKLWQQRLYGKLDEQEMAKTPETPKEFAVDFRPRRDLEAVYTPEEGKGFIRYISGRLESGDLSDVVGQLETAPSVSEEEAKDMRLMAISIHSCGNLSHHGIRSLVMNPRVRAVAIVGCCYNLMTEKLGPPTYKLPFMRPSIQPLNGRVVRESAKCDPHGFPMSERLCTYKETGVRLNITARMMACQAPQNWGEEDSDSFFSRHFYRAVLQKVFLDKGVIQKVYHDPETKPDENTTPFNTSTNPIIIGSLRKSCYKTLNTYIRGAINKLTTHSDYHEQCEVVSQKMGDMTDDEIASYEKQYRHRKRELSAIWSLMAFSAGVVESLIVTDRWLFLKQHTDLVEQCWVESVFDFKESPRNLVVVGIKKRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6Z7</accession>
    <name>A0ABR1V6Z7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663698.1">
        <property type="nucleotide sequence ID" value="XM_066818006.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051066"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046026949" evidence="2">
        <location>
            <begin position="20"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="387" mass="39999" checksum="A6DA1A517C254292" modified="2025-10-08" version="1">MYKALSLVPFLLLGSSVLAAPQAGTTSRCTRDSCQAVVARSGSADCATVIQTTVTPSTRVATVTTTQTQTTQVTQTLTGTQTNTATLSTSTEIDTVTVTVTTTGAMKKRAAITQAVDRRQAPMTVPGYATSACGNYNRFSSACRCNGASTTTITAPTPLSTTTVTSSVNFIRTIRTRSTLTITGGTATATQTSTITSVVTSTSTTTVTTTVDATSTLTSLTTTTTGTATTTSTTTSTTTTATPSPTPFYLMAQGGPNNGQYAFLNGDDPATVQFVPDTGDANVFTIDNMQHLGSFGLFADTLDADAQPGYTLYFDTADTIAQEGYVYLTCSAAPTGTGTPSLLNCTFRNGVAVFQNCPDDDDVIVDTAQDAGCTQFQFVIVPTGSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VBB3</accession>
    <name>A0ABR1VBB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014071</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664077.1">
        <property type="nucleotide sequence ID" value="XM_066818385.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051445"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DUF676" evidence="6">
        <location>
            <begin position="49"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="7">
        <location>
            <begin position="354"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="939"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1209"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1242"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1309"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1342"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="772"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1431"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1493"/>
            <end position="1764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="772"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1432"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1452"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1501"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1542"/>
            <end position="1552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1595"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1612"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1699"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1731"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1750"/>
            <end position="1764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8067324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1764" mass="193438" checksum="C458232139A61D40" modified="2025-10-08" version="1">MSDLKRKVTVRKPNAGGPRPKKHISIVEQGIKQLYPENDATFVPEVDIVFVPGLGAHPKECWEEEHFKWPTDSLAKDFPRSRILLYMYESCWQGAFKVRQFMDNLSMGLLMGLAAHRDKESEARPIVFIGHSMGGLVIAKAVVLADFHRKRFPIMFEAIAATIFFGTPFRGADAASAAYMYATVAEKLDQAIPSKLLKYMETGNPQLRELVDEFLDRVRQVSPNIAITCFWEERDTSLSSLAKLPSVFGNIPLPAKYAMFVTRESATLEGYFNMGLAADHRDLVKFKSAQDPHFQYVRHEVKDRINAAESTVKNRMNSVRGVDQEMTNAIDDALDGGSVPARRKAAAGTFSPSDWVTKDPEYIAWLAEDKTGNGGGSVTIKPVDCLWVRAHEGRGKTSASMSVISDYEKRDTTDRKQNPVRIAYFFCTQSQYSCTAEDILKSLIRQLNKQQGALAFYAKSFIKKAKGDKSAAQVTIENLWQTLQEMLTDTLIGSKVIFVLNNLHVLPENSASTIKLMNFLHTELSDMNEMGSRQTLTRWFITSRESHIVAKALNVDGVRLVDLEDPKYENQVQIALKRTAKSKVESLVKKKKYNKALAYYVSSLLGKRAQNTQWIEISCVQLFELEPAESDLKVRRVLETLPQDLQTLLSNAWRQVFLENGDDCDRIKEMLRAMVLTYEDPTEDELGVLAGLFSSDEKKMELHRLIELCKPLLSTTRNGPVSFLNGVVKSHLLESAEELLGMSAHDIKVQHGILALRCLDHVKQAFDVDIDLENESDGEDDDEEEEEAEDGDGGSGENAEEDSDSDESDGDGESYDVGAEWDDGAESSNGDNDPEVYKVWGLAMAYTVKHWLRHASKATIDIAEDLSAEQGFWEPDSRIRRRWLLEFHRLTNILENDFDASDVKNWTALHIVSAVGFRDLVTALINNGHEGEIAQRDELDNTPLHLAACYGRTMIAQALLDRNSPIDDGIDINSAKTNAISDSYGPVVSAAISSGNREAVKLLVAEGVSLTVDDDRGLDPPLALAALLSDMSMFEYLVEQYADKLSAEEYSKALVKSAEAGRADVLNTLLKFEHEHQYFQQALEAAVGEENWEVSTVLLDKQPGLDCNNLFRKAATAVEDQDDLLGVAWAYSNGAISQETVDSALYHATDCEKKTTVELLLGEPYRGSPNATGPDYGNALTAAAYDGSEDIIAMLFEAGADVNDPAGWALQTAAAQGHMDIVKDFLERGAHVNAFTKNPNFAPGTALQGACEAGRLDIAELLFEHGADPDLGGGDEGPPVIAATKHNEEEILRLLVRKGAALNLRGGHDGSTPLTNAAEFMYRDAVALLLDAGADLDLADAKGDTALTVACAADDDAIARLLLRRGADLLHVNDDGRNALQVALKEGADDCLAILVERTSALFAALRSAMQGGNMAVAGVVRSVEASKQGLEYDDDDGEDENGESGGLSYDDEPKMRDDDRTGEHTQQHGMIEQVSEELKSALGTQISLYQQYSPGHSDADNSTPAAASSTSSSQAPRFSSQAGPGWQQWPQQQSHPLPSISRISQDQTQRPTDVPAGLSISPPPHIRRKPAPAPLSRPSYEGLIHASSNHSNTPSPPPSLTPGRPPKQYMQQQTPPSSSSSSQQYATYNPAASPRPQQSASPSYFPSQSAAGSGTPPPIAPKPTEYTAQGGSGYYGSNPVTGGGSTSYSSGITNGHRSSPPLQSRPQQQYQQQQPAYYPVGQNPYGGWDAQQQQQQQQRPQGAPQRSSMLDRARMMSNEFLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGT8</accession>
    <name>A0ABR1VGT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664235.1">
        <property type="nucleotide sequence ID" value="XM_066814945.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048005"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="5">
        <location>
            <begin position="143"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="374" mass="40395" checksum="8956BB1E1DFFBD8E" modified="2025-10-08" version="1">MAKQTNLATAAEPRLSLPWLARQPVSSVYNVCYLATLVLVRVPYWILNLRQSLMVTLIKASIHGASVLEKPTPLSLEPGKEKEQFLVAQPGSEADYVGPLRSDAVAPAPVGITCFTRKPETTDKQKSPASSVSSSESQPSMVMLHVHGGAFVIGDGRIDQMGYGASMLLRHAGVRRVYSVQYRLACRPDSVPFPGALQDVLTSYLYLVRELGIPAENVVVSGDSAGGNLVIGLLRYLADAVLFSPWVAPAQCLGPDDLVVTSNPHYGTDILAPAFLRWGAAAYSRLVPASDSYISPLGHPFVTAVLEVEGMRWVREMREVTAAGGKRNDVELNYEEGAPHDTLLVGNNLGWDESVREVTGKVGEFIRRKTPGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHE1</accession>
    <name>A0ABR1VHE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_010816</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664421.1">
        <property type="nucleotide sequence ID" value="XM_066815131.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048191"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04813">
        <property type="entry name" value="PA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF406">
        <property type="entry name" value="PA AND RING FINGER DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G02470)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045207448" description="RING-type domain-containing protein" evidence="11">
        <location>
            <begin position="24"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="689"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="394"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="610"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="739"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="413"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="621"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="777"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8070613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="831" mass="89961" checksum="89B2816E17793F46" modified="2025-10-08" version="1">MRPPRIVILALFFAACLFLLCRAITSTLAPAAPTIVTTPANPEKSRFKSLFSLSAPFALFLPNAVITIAADNTTSFAARPAGFGPQLPNKGLNGQLWIGSGFTEETLQDDVGEGELGCSDVPGWNDGNTNVVLKTTSIKESQDKSSSIKTPSGKSNRRAKRDDISKEAATALKQGTKSSKVPVNDGTDDYLHVGLDRSPKLQTDASGLVSSGHADIQSIQEGAEIAGKIVLLSRGGCGFLEKVKWAQRRGAVALVVGDNVRGGPLIQMYAHGDTSNITIPSVFTSRTTAYLLSLMMQPGSYIEDFIDENGKPTQKVQQTEKKKARQQQAAAKVQKPREAVAGKAKAAATKDAEASLAFISNYQWYEPPPSSGQHDWVLVEDFSDEKDKIIRDSMEKAAKGSSTSGSKTTADQKQGDGFRIGVHDWRDPDLVPDLREQDAKTNEKTNEIDAASKQNAKKPKGHNGPQGGSITPSSGEYATKEEPSTKSKSGEPKENTNKGGFFWRLFGGHPDAHRVELPPASTNTPIVKAAPPTHTAIHPPPGDHEGLWIVITPTNGASPFLDTLLVLVISPLITLTVVYALLILRARIRRRRWRAPKSVVERLPVRTYHTVASTPSHSPRIPSPSPPSPTTPLLQSQHGPSRSRPRSRTTTGVAGDLLQANSALQLPGPSPSHEKPSEWKKYMGRQVECVVCLEEYVDGVSQVMSLPCGHEFHVECITPWLTTRRRTCPICKGDVVRSLARGSPSSPRYEPYRDDSDDEFSLQASSSSSNSSSHMPIRNDDADVERGILSPAPRGSLEPARPDGWLGMISHSFRSMSSRPRSAGPSEDRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHF6</accession>
    <name>A0ABR1VHF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010831</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664436.1">
        <property type="nucleotide sequence ID" value="XM_066815146.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048206"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="93"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="721"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="119"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="722"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="783" mass="84563" checksum="C545767B7C90E740" modified="2025-10-08" version="1">MDAEAETMGGGGASPPGVRRACDQCRLRKIRCDKETPCSNCRSAKRSCSSTGLGQKPKEPRQRVLISSQYEKKIDFMGDRLATIEALLRDLSTSPRSANSNSLASSSNTPSDQDRRTRQQNNESPTTTPGGASDNLSPSKTPYDDTSTVFEPDDSETFEGSTSLAAHAAFASDFVATASIAVAPFSGSNPRMEAALSSLKQMVELQNSRTGPGSTTSYFDGTAARTTAAGGRHRSGKGYVRLKDLPMPPMELVISELRELQSAPGSMMLLVVTCFTDQEVFVERCRRLYFHTDHSDIPEALFLNVNAGLIYLFFEKSIRAPAGTAEKATLEKCTAMCQFNMETAIAQLPLLMPATLENCEALLMGASFAVDVSRPSLAWLLTERAANMCRTLGLHQEHTQRGDTPELRRNKALIFWSAYMLDKGLSLRLGRASVLQDYDIGVPSVLERTALDDTDYGGVAGSGHSTAILSLWIKHAEVQGRIYQRLYSPGALRQAGATRAQQVRAVVADLQVLLRETNKLLEEAAARARGGDRDAQMFALILKSDEVGYWSSAALAYRALPPSGTNNGGGGDSAKSNSSSNKSRTFAEECTDAARAAMRSHQECMDMMNDTSLKVIYLHWTILYAPFIPFIVIFCQVIENAGSDASTSDLRHLERFIQSLEAGCGISPAVEKLHRLSTVLYNVALLYAEAKAQQAWDQDMVPVGNEFDLYLSQLGIMPMDESGGGGDPSGGAGNDVNGAGAGGGGGGADDIMRNVQLGDWFSGNNHILGLVEEDLSSFNTSMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIM7</accession>
    <name>A0ABR1VIM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein P1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">60S acidic ribosomal protein P1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011266</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the elongation step of protein synthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">P1 and P2 exist as dimers at the large ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664871.1">
        <property type="nucleotide sequence ID" value="XM_066815581.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048641"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05831">
        <property type="entry name" value="Ribosomal_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8071063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="110" mass="11140" checksum="7DE2AEA5FBD49E5F" modified="2025-10-08" version="1">MSTAELASSYAALILADEDVPVTADKLQTLIKAANVADIEPIWTSLFAKALEGKDIKELLSNIGSGGGAAAGPAAGGAPAAGGAAEEAKAEEKEEEKEESDEDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIQ8</accession>
    <name>A0ABR1VIQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011328</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664933.1">
        <property type="nucleotide sequence ID" value="XM_066815643.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048703"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03357">
        <property type="entry name" value="LbH_MAT_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051159">
        <property type="entry name" value="Hexapeptide_acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416">
        <property type="entry name" value="SIALIC ACID SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416:SF76">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="233"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="9"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="272"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="402"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="112"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="367"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8071125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="691" mass="75837" checksum="AD5105C41BBB4F50" modified="2025-10-08" version="1" fragment="single">RILAQCAMASFTALNGGDSKPTDRASDSPTNKRPDSEERPEIVVPGPTPRPPSRDISSNQRDQWPASGPERSSYAYPDVEGSHKRKRSNSLELRREAPSAPEDRTPAPPSHPEPRDVYGTSQHHERDYRPYGDENRGERSDPWHSQYSREERSAYETQNSAGSLASPSEGQGEDSLRRSQMDSQQGYSPTSPDADESSYYGGSYTPEHRRDGTVIQSDPKKRKRNFSNRTKTGCLTCRKRKKKCDESKPECNNCLRGGFICQGYANQRGYQKMENKPPAVPLESKDPSYVPPGAYGMPQQAPYPSQPAALTVPPKREPPPPYRGPSLRIDTPQGRPVLTDDERTASTIPTASVGSPENKLSILPSAYPSQQNNPFPTPISAISSAANFESRVLSKEYHQRIPPLHDASRTEPETPQSSIPNTTLPQINILNAPTRTSSPGSHHQQPPPPPPPPASTTSTTSAQVAAQLALSHSNFPPPPRQSTQKELMLRSDWYQPFNKELVLERERCSAACWRFNNSTNPNNGVSGNERSRLFREILMPKEPVDLSLSQRSHAFNVGRVGNDVVIEAPFTCDYGYNITIGQNVFIGRNCTIIDPCSVKIGNNTYIGPNVSLFAATLDTNPAKRMGSKSLQKGEPITIEEDVWIGGNVVVLPGLKIGKGSTIGAGSVVTRDVPNFTIVTGNPAHVLRGIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJM9</accession>
    <name>A0ABR1VJM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011647</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665252.1">
        <property type="nucleotide sequence ID" value="XM_066815962.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049022"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF314">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="11"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="384"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8071444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="400" mass="43626" checksum="82F6773D833E6708" modified="2025-10-08" version="1">MASDNDSKGLKVLIVGSGLAGLTAARVLREHHAVTVYERGGAAVATGGQGIIIGSNGTKILNPLGYEGEGPAVGGVPIRRFRIFDAQNNMIEVADMDLRSRFGTETLGQKRSDFRDELVRLATAPSRELGIEGEPARVEYGNAVVGVEPEEGVIVLSDGTKVRGDVIIIADGIHSRLRPTIVGAGCPTAQKTGLSAYRVAVSVEAADRALADLPPPRWWTPEMYRNASYFLNGPEGSRRFITIYPLRRHTCFNFSCIMETQVSSKSTTESWHAEGDRDKMLEYFGWDEGLKRILSAATEIKSWELQDLEPLPTWTRGRAILIGDAAHAMTPMQGQGANLSIEDAEALRLLNNETGTGTVRREDVPAILRRIESVRRPRAAGALDRVRDTQGRLTGHEKFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKZ0</accession>
    <name>A0ABR1VKZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010812</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664417.1">
        <property type="nucleotide sequence ID" value="XM_066815127.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048187"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8070609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="56937" checksum="6DE7745168AA02C1" modified="2025-10-08" version="1">MASDIPLRPISETLNSHFLTIASGVAILYATLRFVYNAYFHPASRFPGPRIAAASNIWYAYHWGSGKYPSAVLKALKKYGDVVRVAPNELVFITPEAFNDIYNTYTNGREHFPKNDFMALGLGDDGITWEQNPEKHHADAKKLTPAFSPKALRAKEPILQKYTDAFVERMKQLRSREEGIELKATMDWFAMDAAADLAYSREMHHLRDVKSSRFLDQLWQASVFITANQVFKKFPLLSPLKFLFVPPSFVAGFSERRGKVEHLDHFEQFVPADGPLPTKKEQKHIEVVTGHLVVAGYEPIASQIYGTIMFSALEPGCLDLLVREIRGAFQSYDDIRPNKLASLQFLHASLMETLRFTVLQSSGQARVSPGAMVDGHYIPKGVNVSYGFLAFTRSPRYFRDARSYRPQRWLPRDHPQWDPAFQNDATDQFHPFSQGPRSCVGMPLAWQQTRLFLAKVLWTFDVEVLPGQSIEFERDFSMYAMWNKPKFWVRFHPVQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VM52</accession>
    <name>A0ABR1VM52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011503</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665108.1">
        <property type="nucleotide sequence ID" value="XM_066815818.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048878"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="18"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="226" mass="26652" checksum="443D1670443E851D" modified="2025-10-08" version="1">MAYVRSELRATHAKPNCGPYEILEQSRNGPYSKRRFHELVMVYHPDRWVHGTYHDIPKATRIERYRLILAANAILSDPLKRRAYDEQGVGWSLGHENFLHNKHTQATRSRYSSNMNASWEDWERWRDEEFMSQQADANGRYPMRSKQQAIFMCNRRFLLTLLLLATTGSCLMLAAVLSKAKIMSEHDLNLHKRILEELCEMGNGTYHFDRRDRIDLFLKRRVATIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT55</accession>
    <name>A0ABR1VT55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase M12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665383.1">
        <property type="nucleotide sequence ID" value="XM_066813421.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046481"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="1">
        <location>
            <begin position="61"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="176" mass="20390" checksum="288EB1B840B9EA96" modified="2025-10-08" version="1">MLIRFKFLEHGNRGPSTIRISFTSTGPPNSRLGLWRKDDDPNEPTMRLRVVFSEPLWSQFMILHEFRHALGLEHQHQHPNSGIRWNKSELKRQYRYTDDVFRRNYATLSSLAATCYDPRSIMHYRILPGETYNRAPWSAPNSVLSVGDKMLLMSLYPSDKPLILAPGLVLDPKAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTD1</accession>
    <name>A0ABR1VTD1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Arsenical-resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_009182</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cell membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665459.1">
        <property type="nucleotide sequence ID" value="XM_066813497.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046557"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057:SF1">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="ARSENITE EFFLUX TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8074519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="384" mass="41893" checksum="2E1E9F92AE8A8600" modified="2025-10-08" version="1">MASSEPHHLDTTRYEKHQASPGAVENQTDSTTTPEHHDVRKVSAFKALGLLDRFLAVWIFLAMVVGVLLGNFVPQTGPALERGKFVGVSVPIAVGLLVMMYPILCKVRYESLHEIMSHRGIWKQIAFSVFMNWIVAPFLMPGLFSPDKSELRAGLILVGLGRCIAMVLIWTGLAGGDSEYCAILVAVNSILQMVLFAPLAVLFIRVISHDASNKINVSYSVVATSVAVFLGIPLGAAIVSRFTLRAIAGPDWYERVFLRYAAPWSLIGLLYTILVLFASQGHQVVHQVVSVVRVAAPLVMYFVVIFTFTLWVSRRLGFGYALAATQSFTAASNNFELAIAVAVATFGADSDQALAATVGPLIEVPVLLGLVYIVKLVGERYKWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU18</accession>
    <name>A0ABR1VU18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009401</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665678.1">
        <property type="nucleotide sequence ID" value="XM_066813716.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046776"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039328">
        <property type="entry name" value="WDR89"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="56"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="334" mass="36309" checksum="C0C19177765CE2ED" modified="2025-10-08" version="1">MFNLSCVDGFRYPGSDEVYVLDLIPLAQGPATISSDQKLCAFNPLSLRPGPVTTLQTKHGNLTCAKAFDLVGSVVCTAGEDGSVSLWDLRKDPREAEVARLTDNQAPVLSLACSSTGFSVVAGTELKSSQASILIWDVRSTPTPRHQYKEVHSDDITELNFHPTNHNILLSGSTDGLVNIYDTQITDEDEVVIQTLNHDASIHHAGFLNDTEVYAVSHDERFALYNIAEDQEKGSATNDFGDMRPVLNCQYIANVTAKANGAGAVIGAGTHENQMFEMVHLTKGTEWAFDKENSVGLPGAHSSEIVRSFCFYDEAQMVFSVGEDGYIKSWKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW76</accession>
    <name>A0ABR1VW76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 79 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010156</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666433.1">
        <property type="nucleotide sequence ID" value="XM_066814471.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047531"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539430" evidence="2">
        <location>
            <begin position="20"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="3">
        <location>
            <begin position="473"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="596" mass="63784" checksum="8E622FFA0917B1F3" modified="2025-10-08" version="1">MHPTSTLLSLALLGGSVGARPSAGLGSNHHHHLHQKRSGSSSGGSGAAAAKTLPIASTSPTGAATVPADFLGLNVESSFMNNYNNAFSNNLVSALAKRMSVPPVVRIGGTSGDEFVFDPNQDDHVKTCIAGECPTGSAASYKIGPGFFEGYKAYPDARMTIQAPLGPNVNETLVREFVRRAWEARVGPVGSEWKSKIDAIALGNEPEFYTSDPAKYVRDTLEIEQIVLDELKLEGDDRKIFEAGNNAKQPVSQYDVSDILKQGMNKNGLIKATAEHLYQIDTTQPWDDATMQKLMLSHKAITHRLDTQYMPSLRASVGEGIPYMISETAAVLASPINTFVSGFGFALWLVDFSLANAARGVARVNHMGGRPVANHVLWTPDHTAGLRNPGPQARALRGRHDGRRLPPADERGRRRGDRGVTGGSDGGSDGGNSSPFSVFNEKRKQDAHVVDAEENVTIQELDLDTDSNPHMSAYAVYSSGLLERVALINMHLYNGTAAAENGARRGSETFKIPVGDDVESVRVQRLHADLGAAAMGFDYGGEQHNVTWAGEQWSKKIDGGEGHYTQGNGQVVETVTVSGGVASVEVPDSEAVMVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWH0</accession>
    <name>A0ABR1VWH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666519.1">
        <property type="nucleotide sequence ID" value="XM_066814557.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047617"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="89" mass="9803" checksum="AA4F1D303DAA1144" modified="2025-10-08" version="1">MDKPDDRNSGKPKPNVTSANVDLGSTESGQATKASNTSRKDQLKRLYLRRKKAREVLDATLPKTAYSLLGQDAKKIIRGAIDECLDDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWW7</accession>
    <name>A0ABR1VWW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666669.1">
        <property type="nucleotide sequence ID" value="XM_066814707.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047767"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="29649" checksum="D30C84B0BF54CD23" modified="2025-10-08" version="1">MSDATETPLNPCPIEPDDDEIDRQLKSALQDLVNGGVEVTTAAKIVDDLIVSDCQRAYEAHTASLRNINKPKENGEYTETFSKPPGMDWISLENHRFLQELLRLPPRTVQYISGSGDVVDYTFWEDDRRNDQFCQNMRLLDTEYVNFSAFLARVFARGVIDTTRFCALVTKDGLTHVGAAMWEMCEKKAYAAKGFNTKWWGRWQARFEQVAEGDSGFSDQAREAAAEALKQMVVLKEDGSTGLSVIEAFGLNVKDWEDEELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWY9</accession>
    <name>A0ABR1VWY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">EF hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_010380</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666657.1">
        <property type="nucleotide sequence ID" value="XM_066814695.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047755"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02340">
        <property type="entry name" value="ZZ_NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF187">
        <property type="entry name" value="EF HAND DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="8">
        <location>
            <begin position="137"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="309"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="45"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="494"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="619"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="726"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="764"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="835"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="445"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="622"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="767"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="788"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="835"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="872"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="957" mass="108278" checksum="107DFF67DA0C4168" modified="2025-10-08" version="1">MSSTSTAAASTLTRPRIAITFVSAVAAVSISYYCISQYFQASDTGADGPTGLHRSNAVRRSRRRSLRPDDSSESDAQAQGDENADTNNATLPLLGPLNDDDWYNDPSQAPRQRTGENIVTLLFRVSEDNARRNAYVHRGCQCNGCGMVPIRGIRYRCANCTDFDLCEVCESQGLHIKTHVFYKVRVPAPPFGPRQIQPAWYPGDPDNALRNLPRHLLAKWANETGFERVELDAFWEQWTFIANTEWRDDPTGLCLAMDRKTFERCLVPSGGYQHTTPNLIHDRMFAFYDTNKDDLIGFEEFLHGVSYRKRKDKLKRTFEGYDIDGDGFVSRKDFLRMFRAYYVLYKQMHRDILEGLDDHMMAATEVQQLVNSRAPLSSLFGREGRVPPADHSRPMEGKVFRSNGDVDIHDGKVGVINQDKPDTSTREDILSGLFARNTNQSFFTESFSSSSRHPRSSNADSRYWSGLTSPPQNIVDLESLVNGDYSQLNDIIASISRDEPSQRRVEDDDSASSDDQDRSSPDGDADRAEPEIRFGDSRGSIRYINGTNRRAATITRVPHPTGLASSQRLGNERRRRVQARRQLLERWKRRQFYLDVEEGALPPQGWDENDDVLESLNGVAESSKSAQPAPSPRSRSSSKVRFAEDTDDFDIRSNPSTSSRSVPERWGGMEIPDAERDAGKEILYQVTQQAFNELLDDIFKKAEDLAIRCAETRAERNKYRHLFEHLEVDTNTTPPDDETVSGSGAHPVQQQSLEELLEVSGYTVEPAPDHTEPSHPKPEEENAPNDADDAHTTTEHHSDPTPALPTTVLYRDPTMPQFRPNDEAELLLSQGLSYVETSTPSPSSVEPAHISRKKATDASTSDDKNTNGQGWSEEEENENENENNNTEEDKHQQAHIMHATLETWKRLDVAEEEAKTRGGWGKLSFREFEDIYREHEFQDSTRNRLDYLGSWIDFCIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXK5</accession>
    <name>A0ABR1VXK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009548</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665825.1">
        <property type="nucleotide sequence ID" value="XM_066813863.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046923"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="40"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="314"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8074885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="343" mass="37755" checksum="CA8F3F3298FD03F6" modified="2025-10-08" version="1">MASIPGLPPITPEQMNESKQPVIIHVTVWLHVVSTLCLALRLSSRRVKRMKLGVDDWLIVAAQAVGYGHAATILTMAAYGAGQHIVTVLMKPNAAHAIDVQLKAGYAISPLNTTQLTLTKASVLMLYLRIFPQRYIRLGVYVIGTILAGWWVTFVALNLFGCNPVSKGWADTESTCLSRSHAVNTIGTIFDTIINVFILSLPVRAIIQLHVKRWQRIAIIGLFLLGGLSTVSAWLRWWVVEEHRNDPVADTMYYSYKTLVFLTVEMATGVMGVSLSTVTPILSYFTLRMGFKRASMALNKADVDGLVTIGGSDGSVDGPTSHRDSRPRFFNRRTGEQDTAIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXP6</accession>
    <name>A0ABR1VXP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylinositol N-acetylglucosaminyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009322</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665599.1">
        <property type="nucleotide sequence ID" value="XM_066813637.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046697"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009450">
        <property type="entry name" value="Plno_GlcNAc_GPI2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12982">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN, CLASS C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12982:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06432">
        <property type="entry name" value="GPI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="367"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="28"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="186"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8074659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="52320" checksum="5B1038EFDBC18522" modified="2025-10-08" version="1">MAGTGMRQSVVGPYSTLTPAAVLPLDHLTTSPRSSRSHLAPEDAFNAASPPRRSGGFDHSSNNNNNNMKSKFGSRSRSRRRKRNWKKILWVKQSYPDNYTDQTTFLDSLQRNPRLQPYEFWPLVADTTVIVQQVCSVTIFVVCFVGIFTERVSPVAVVGWGSFATFVGWAVWDWWVGQEGEDEVLQRQNSHRSRGAWQPRQDGGSANSTTAPTTPSAASSVTNLGSTERTTSQGNLIAMRSQHGGSVTSLHSNVSHTSRLLDPQDGLRHRPSSPLRRGRATLRLSTIKSASLIYFTILGLSPILKSLTRSTSPDSIWAMSFLLLAINIFFFDYSGGVGVKFPASLSTNAALMASTVLASRLPSTGQVFSLTLFSIEVFGLFPVFRRYARHRSWRYHVTLTVLLTVGAGGGMGLILGEGEMDGLLGVLVRAFIVIVAMGASSWWLIGLQKYKNAMNGPWDQARPIIISRRQWEYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W122</accession>
    <name>A0ABR1W122_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666753.1">
        <property type="nucleotide sequence ID" value="XM_066814791.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047851"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047247741" evidence="1">
        <location>
            <begin position="20"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="169" mass="18217" checksum="FEB6862DEC3B93EA" modified="2025-10-08" version="1">MKLTIFSTILAACSVLVAAQANCDRRNQPSTNDVKGAIRDWLADVNAVNAFVDKAPNVSSNQASQALQFAKREPGDLMVLSRICGVSGRYTAAVADLNKVFGGVLTNLQSIVNNSKNAPTAVANINKIRCCNVLPDLDVLWREAAQRYRIQGQVQTTVPRPRACASVKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W913</accession>
    <name>A0ABR1W913_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA mismatch repair protein PMS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667377.1">
        <property type="nucleotide sequence ID" value="XM_066812035.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045095"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03484">
        <property type="entry name" value="MutL_Trans_hPMS_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="entry name" value="MutL, C-terminal domain, regulatory subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF52">
        <property type="entry name" value="MISMATCH REPAIR ENDONUCLEASE PMS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="5">
        <location>
            <begin position="217"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="4">
        <location>
            <begin position="846"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="359"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="470"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="489"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="535"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="666"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8079902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1084" mass="118809" checksum="BB5F9EF8B9BBEAB2" modified="2025-10-08" version="1">MATIKPIEARTIHQIQSGQVIVDLCSVVKELVENSVDAGATTIEVRFKNQGLDAIEVQDNGSGISKENYGTLALKHYTSKLLTYEDLTTLETFGFRGEALSSLCALSQFSVTTCSAADAPKGSKLEFETSGKLKNTSVVAAQKGTTVTVQSLFNNLPVRRRELERNIKREWNRVIGVLNQYACILKGVKFTVSQQPNKGKKIVLFSTKGNTTTRDNIVNVFGAKTLTVLIPLDLKLEMQPTYTVKQQRTSTQEHQNTQEIKILGHVSRPAHGEGRQTPDRQMFFVNGRPCGLPQFAKVFNEVYKSYNSSQSPFIFADIQLDTHIPECSTILESHLSSFSKHKITRFLCRNLLAPKNSVQETYNQPSRHYRPRAKKTEAPEIRNDAQDEEDGSVSRDSAEPGDPSGQGTHGVPDSVHTSSNKQTRSPAVVPGEGRGMGLLSRWVRRSSPDRRDTASAATSPELQVKVGPSRSKEKFFPRPDESESRTVVAETTNDGPSSSIEMESDSADRAVNSTDYQKSSGNAKEGLEVDDHIQSSEPPISSIPTPSRLPQSRPIPYSPSRFHRGSPEVATITIGNETVTSIIGSPAKRPRLDQQKTQESKPKRATKGKDNPLPSFQGRLTQMFSAASAAKPRDATRLDASLSQDDSSESEEQSRSPSRASSEGLFVEDQDSNDSTDDAVTQQASPEPKEEEEEEINMSDIGADPSATYDHSDGGDPDEVPASPSPSDGSNYEDEDDKKAREDDKVQSMIDAAEVAAQANSEETEKRQQNFVKGATKRKGATYPLLQTMRLAEGQLQAGLRSLAQTSVDSSSGDDTSLPTDNLHATDAEEKLSLAISKLDFGKMKVVGQFNLGFILAVRPGMADPGQGDPEAAPAATDDELFIIDQHATDEKYNFERLQASTVVQSQRLVQPKTLELTAIEEEVIKENLAALEANGFLVSVDESGYHPVGSRCQLLSLPLSRETTFDLADLEELVSLLTDHPAASENTVPRPSKVRKMFAMRACRSSVMIGKSLPHRQMEKLVRHMGELDKPWNCPHGRPTMRHLCTLGAAWMHSSGWKEGDGFDGTKAEPTDWAAYVKSSRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9D4</accession>
    <name>A0ABR1W9D4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007948</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667605.1">
        <property type="nucleotide sequence ID" value="XM_066812263.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045323"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="295"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="39777" checksum="5554D87CA75CCA9D" modified="2025-10-08" version="1">MPFAQLLVGSPGAGKSTYCDGMHQFMSAIGRECSVVNLDPANDKTNYPCALDIRDLVTLEEIMADDQLGPNGGVLYAFEELEHNMEWLENGLKELGDSYVLFDCPGQVELYTHHNSLRNIFFKLQKLGYRLVVVHLSDSFCLTQPSLYISNLLLTLRAMLQMDLPHINVLTKIDKLSSYDPLPFNLDYYTEVQDLNYLLPSLEDEAPGLRSEKFARLNSAVADLIENFALVHFEVLAVENKKSMMHLLRVIDRAGGYVFGGAEGANDTVWQVAMRNESSMMEALDIQERWVDSKEAYDAAEKEEDEEQAKRMGHADPSGTGATTPELIPDDDDDPYDGLPPPTGDSGIKIVRSNRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9H0</accession>
    <name>A0ABR1W9H0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Polyketide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_007934</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667591.1">
        <property type="nucleotide sequence ID" value="XM_066812249.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045309"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23297">
        <property type="entry name" value="ACP_SdgA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="12">
        <location>
            <begin position="915"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="2377"/>
            <end position="2454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="915"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1075"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="945"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8080116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2461" mass="268649" checksum="7CC6D9B9ABF4F6DD" modified="2025-10-08" version="1">MPLIHEKVEATPQAEPIAVIGIALRAPGDGSDPEKFWNMLLEGRSARNFKVFDAPFFSVTPKEAKAMDPTHRMLLETTYEGFESAGLRLQDVAGTKTSCYIGTFTADFPSLQARDNEGPSIYHATGTSASLASNRLSWFYDLKGPSMTIDTACSSSLTAFHLGCQSIRTGEAEMSVIAGANLMFGPDMSILLGAAKILSPEGKSKMWDANADGFARGEGIGVLILKPLKAALRDGDTIRSVVLATAANEDGWTPGISLPNSEAQQELIRTAYAQAGVDPATCAYVECHGTGTQAGDPLESKAIFNTIGSNRTTDLYAGSVKTNIGHLEGAAGVAGVIKASLVVERGLIPRNLWFEKLNDQISLPDNVKIPLDTMEWPHQGPRRASINSFGFGGANAHVILEDAASYLARTGQTGRHFTAPRLITNGINGHSNGTNGTSKEDTKSKVFVLSSNDADGVARQVESLQSYLSTKSDSKSIDLMDNLAYTLSSKRTVLPWKSFAIASSSETLQKSLENVPAVVRSSNSAVPKIAFVFTGQGAQWWAMGQGLSVYRAFRESMTYSQEVLTALGCPWNLEEELSRSETDCKLRMTEYSQPACTALQVALVQLLRSWGVQPVAVVGHSSGEIAAAYTAGFISHEAAVKIAWLRGQVSATVSKNGGMIAINASAETVEERLSSLTQGRAVIACMNSPRSCTVSGDKSAIDELYNSLKKDEVLCTKLPMDVAYHSFHMEAARQQYEKALAGIPHEVPETALPMFSSVTGKLVTPEDMKPSYWIDNLVSPVNFTAATRALLHHIQGKTRNHDRTAFASVFVELGPHSALRGYLLDIFKAEDRFVDLSYASVLRRKFNGVDTALQAAGELWSKGCQIDLNLVNEAPEDVKMLVDLPPYAWDHSPSRSFWEESYLSREYRQRPKPRTDLLGYRVPGVPDPTWRNFLRCNENPWIREHKVQGDILYPGVGIVIMAIEAAKEIADINEEIYGYELRDVAITTALRVPDTEKGVEVQVQLHPRRTGTKAGPSSFLNEFTVSSWSEETREWTVHARGLISLTYKSSLSPSMQKELELESAAKKQALLDARATCQRPARSFLYDQVETIGMMYGPTFRNMTELFAGPDSSYGIISIPDTKSVMPCHFEYPFVVHPATLDSILHLLFPCITGEEESLSEAVGHCTAKKTSYTTWTSAINVCENDDEPLIIMEGVGLASIGGSGSDSTAVTQESRASCFGQNWHEDVDLLQPKQIKEIVYSRTLKSKDDETVLDMLEYVCLYHIYRCLDWFKGEGKDFIPESGFWKSYVEWMHDTIKDFPPLAEDPAEVQAELDRCRDAIVHSPSGDITVQMVDRIGDNLPKIFMREVEPLQVMTEGDLLYTFYRGAFGTSFNTNVAEYVGLIADKSPGLSILEIGAGTGGTTYHVLERLRNPDGSSKAAKYFFSDISPGFLAKAAERFNTDASIMQFGTCNIEELPEEQGFAPESFDLIVCANVLHATKSIQETLDHCKSLLKPGGRLVLSEVTIKRIFSGFIMGPLPGWWLGEADGRFGGPLLDVPEWHTALIKAGFSGVDMDVRGDREESKEPVSLIISTKPVSKISKTASEFLVISAATPESDKLSAVIAGTIKNAGKIVDTINWGQITKDTVSGKYCICLAEWESPMLAELTDDNWDKLREVVLGSAGTLWITGGAAMDTHEPLKSLMVGLARAIRNEDAGVLLATLDLEPASSIDMEQASDAVLRVALEHSRGETSDGEFAARGRCVYIPRVERIPNVDSSLRKYEAKGDPEPTSFTGCGRPLKLTIKTPGLLDTFRWIEDELYYEPMPEDWIEVKVKAVGLNFKDVLVALGNLAEYKLGVDVSGVVTRVGSAVKDLKPGDKVMTASCDTFATFVRFPAKGAIAIPEGMDFEEAASMPLIFLTAYYALITAGQLVKGEKVLIHAAAGGVGQAAIQIAQSIGAEIFATVGPEEKKQLLIDQYGIPEDHIFSSRDTSFYKGIMRATTGEGVDAVLNSLAGEALRLSWHCLAKFGRFLEIGKADLFANTGLDMKPFLDNKSYMGINLLDFENNPVQPIQRFTMCDVEQAFRYMQTGKHMGKVVISVDDADIVPAVPRTPKVGITADATYVVAGLGGICREIGRWLAEKGAKHLVLLSRSAASSEENKAYAAGLEKTYDTKTYAFDCSVADKSALQSVLDRIQHLPPIRGCVTGAMVLHDTLFDKMTAAHVRTTVGPKVHGTWNLHELLPRDLDFFVMLSSLAGVMGHRGQSNYGAGNIFQDYFASYRRSLGLRAMTIDIGYLLSVGFVAEHDEYVDHVKAMGLKVMRNSDLHGLLSTAVEGSDAHPAQIMCGLPFNDHDDAWYWIQDGRFAALRNLAAGASAGGSATISLREELSRCGRVDEDSIDLITAAMVQRLAKLMMMPEADIDAARPLSAYGVDSLVAVEVRNWVAREVAVEVSVFDLMANIPMRQLAGDLARKSSLLNQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9W9</accession>
    <name>A0ABR1W9W9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ketosynthase family 3 (KS3) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667692.1">
        <property type="nucleotide sequence ID" value="XM_066812350.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045410"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF21">
        <property type="entry name" value="NON-REDUCING POLYKETIDE SYNTHASE AUSA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="5">
        <location>
            <begin position="422"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="794" mass="85881" checksum="563115EF2FCB993D" modified="2025-10-08" version="1">MATFKQPVSSLLVFGPQTRPSPDDLAELRHELINNPTLSKVLAAALDLPRFWQELNLFIPDLAQVPAESHLHEFVEWLKGERKAPYCAQQCPITITFILNFLIQIKQYIRLLRSLDIEGADDAQSLVLERLRDGGVHGFCVGFLCAVTVSLSKTEEDLADNASRALRLALAIGVHVDKDASKEATTCISARWRHKQLNALDKALAVLQDYPEAYIAGITDGTSMTITVPDAHLAGLVPGLEGHGFSVREIPVDGRFHSSVYTSAVEVLVDFFDKMHSHRFPGPENLQMPIRSSTDGKAIFQGDLVRHALENTLLKPVDWYRTLTLAMADVPQKQKHIALAGLSNHFPLSLMQNTDIQLQFLKEVGGTDTEICDNFSNTTGQEPTPDSINGGDATDRSWIFASDEESSADDSATGDQPFDFPRHSVAVVGMAGRFPGANSVEELWSLLSAGRSCAQRAPDRIGLDCLSDDYAQKKWWGNFIDDPDTFDHKLFKKSPREALACDPQQRKLLEVVYDALESSGYFGAQTCRTSGSTDYGCYIGATQNNYVNNVSTQPPSAYATIGTGRSFISGAVCHYFGWTGPAITVDTACSSSLVAIHTACQAILAGDCSGAVAGGTNIITSPHDYRDLQAAGFLSPTGQCKPFAADADGYCRGEAVAVVVLKSLAAAIEDHDRILGVVMGSAVNQNYNEAHITVPHSGSQTSLYRKVMNMSQVAPGDVTFVEAHGTGTTVGDPIEIRSLRDAFGGASQRDSTLYFSSIKGNMGHAESAAGVAGLIKVLLMLEHGQIPRKPATSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAQ4</accession>
    <name>A0ABR1WAQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668051.1">
        <property type="nucleotide sequence ID" value="XM_066812709.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045769"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="9"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="545"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="698"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="924" mass="100354" checksum="A9AC9711BF76CB97" modified="2025-10-08" version="1">MPKLDPTRNYYADLEVSPTASVDEIKKQFRKLALKYHPDRNPGREAEVNSKFQIIQSAHEILTDETQRRKYDDTLRSSRSRYPGASGVRGNPWQDAAKAYPPPPRRAPATNNAQSRPASGAQSRPTSGAHRYSNFTGGSVPRGGKTASGKDGADARSNYQAWESMRGRPVPPPPTPGRAPTSATRESKASEPEPSIPRAASQKQKAQASFGNSARRAGYTPRSPGLARNSSAQVPPDPLAQFRENYMDGHRSTPYHTPGGEKTSLHEEGSGLGRAKSTRESSRKAGGEDLGTDTFPFPTQRPRSSSTPKTSSNDGGSEDSGRASNAANIGSRRTANNGNTFPSRASDRYKPRPSTTDSTTEPFTAPPGQPTTEPSTASTGAGPSVYALPTTPYFIRSRHPYISPFCSLGGQTTKTGNSGQVQAQARDIQAASGMRTSSGVVNPEMLQRRPFKKVLAKENLNPTTLEGHAAALFGDTLFGTYDEFKTGADYLNSSFTFSNDPSTSAQSPGQAQFSANGSSENIDTRFVDDQNEDGWEFKAGGPSVGSPTPSRKGSRSGSRIGRSPARPVPRPRQATNPMPATQESEEEVSKAGFSAGEWSEKIGPQHFVPQPTKSVPGSPTRRAPSRKNSKPVKMTMGTAGLVEDEESTNGVRNIHVEPSRPEWRAGHVEGAAPPVPPRPTSTIEAANATGAGRGDMQSNSAPASANPFAAPVGGSEDSEEFLTTFADFKKCEPFAEPAPTGLKSFADLKSTLPFDSKPSETIPLEREQPVGVSLDFPTPPVAPRLPPTMAVPSIRPSVTQFRKYAQDFGNYMDKWEVFNQKVLDHFVARQEQYKLRRQQLGLAWLDAAHGGDIARVYQNEVEQDHEVRKKWSQWCDEHQSRMRELAGKVLWVVTTQYRKLRSDAELLDPEDLVHTSSHWPIESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB35</accession>
    <name>A0ABR1WB35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cation diffusion facilitator family metal ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_007186</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666843.1">
        <property type="nucleotide sequence ID" value="XM_066811501.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044561"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF5">
        <property type="entry name" value="DIFFUSION FACILITATOR FAMILY METAL ION TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="16"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="11">
        <location>
            <begin position="270"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="339"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8079368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="393" mass="41717" checksum="29A259DEC4732313" modified="2025-10-08" version="1">MAGLGLTSKQKLIGTIAISFSFFVAEIVVAFMTGSLALLADAFHYLNDLIGFVVALVAFIISEDAKSPQEFSFGWVRASLLGAFFNGVFLLALGVSIFLQSIERFISLEKVENPKLMLIMGCVGLTLNILSAALLHEHHGHHHHSHGESNTVSPDAETELPSTDGSGTLTPIDTHTNHRHALPKFQSSSTSTGRDLGMLGVLTHVLSDALNNVGVIIAALVVWLTHYDARFYADPGVSMGIAVMILLSSLPLVKNSGRILLESAPVGVDLGDIPGIESVHELHIWRLDQTKAMASAHVVVSEPDTTVADFVERARTVNECLHAYGIHSTTLQPEIVPAAASPSTSTSTTTTLVSSPSSPAPTIKSGHGDKAACQIVCGKLCEDLKCCAVSTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBF8</accession>
    <name>A0ABR1WBF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668306.1">
        <property type="nucleotide sequence ID" value="XM_066812964.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046024"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="335" mass="37474" checksum="58E3864F4A1DF8F4" modified="2025-10-08" version="1">MSPYDVPKATGADEKYLKDTQRRERPSKNERREQGLPSSSETSGKGPAAAASASSSAAAGPAASAPTASGNAEDDAVKVPRRQRSEALEVFRARQIAFYNKPPPPLEKRRADETIADFLARKERYYSIYKKDDKQKKPERSGKNKTKSERSGGSKASNDKGTGPDVMPTATNLAQTNRDRDPTSCIEFPAELFDALTQFNRSVYEEHDETLLQQGYAPSPVYVLVLEQNRPGKPYFSVPRVLPELRDAAGMAHEDWKESLAQLQKDHPDTKWTKKFWYKATGDVRGSARLAWYVDRDGDNKGLVTLSATLPVHDEKEPKYQMTVKVLRHKKIMLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBN1</accession>
    <name>A0ABR1WBN1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008737</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668394.1">
        <property type="nucleotide sequence ID" value="XM_066813052.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046112"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF158">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="56"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="450" mass="49411" checksum="0C6AF4E374FE2363" modified="2025-10-08" version="1">MATPVAQTSTAFETRIPAMPPPPGATSNFDHPDTLVLANYIAMGIALPFITIPFLLRCYVRLWRKRTWIFEDWLALIAWIGTVSFCGSGASTMAHYGGRHTWDVTEPQAQQAAYQHHIRDPMLTLCGGGSQWFNVVSIHYGVTICFVKLTILWLYRRVFSPARHGPFDVGIVSLIVFLVGFYVATNVAKIWQCVPREKIWVTSLSGSCISISTLLNVSGIVNTVSDFVILLLPIKAVWNLNLVARKKITVVLVFTFGLSGPAFSLAGLMVRWSGTGNPDKTWVHPEIIMWGVSFHLNVLAELTTGVLCFSVPELGLLLRKKPKPGPSDSILQGRYLKEDSAYLNKRSDRSGSSSNSGGGEPYFTGLSTIISSHIVAVKSRSRSRDLGYTASQGTVTGGDNSYYELDERKGSQTTISFAQHGDGVGRCPTARSEQNGVIVTRDFRVETSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC26</accession>
    <name>A0ABR1WC26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Aromatic-L-amino-acid decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007833</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667490.1">
        <property type="nucleotide sequence ID" value="XM_066812148.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045208"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1340.10">
        <property type="entry name" value="dopa decarboxylase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF70">
        <property type="entry name" value="MIP05841P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="55429" checksum="8E51C25F325943F4" modified="2025-10-08" version="1">MDSKEFREAAISSIDQIVKYYDTIEERKVVSEVEPGYLRKLLPDHAPEDGEAWSDIQKDVEDKIVPGLTHWQSPNFLAWFPSSSSFPAMLGEMYSTAFTGAAFNWICSPAVTELETIVMDWLAKAFALPDCYMSTGPTHGGGVIHGTASEAIATVLVAARDKYLREATKGLAGEEQEDAMAERRGKLVALGSAATHSATKKAAMIAGVRFRTIPVHAKDGYRLTGESLRSTIQALRAKGLEPFFLTATLGTTDTCSIDDFDSITEVLSEPAPAGHGEIWVHVDAAYAGVALVCPEYQHLTKQLSKFHSFNTNLHKWLLTNFDCSCLWVRDRAWLIEALSVNLAILQNSYTSSGLVTDYRDWQIPFGRRFRSLKVWFVIRSYGIKGLQAHIRKHVGLGEMFAELIKTRSDLFEIVTGPRFALTVFKLKGHDSAAITIDEQNALTKKYYDNVIAEGKIFLSSTVVGDAFALRHCPATPFVEEVHVKKHFEILVANAETTLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC55</accession>
    <name>A0ABR1WC55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_007562</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667219.1">
        <property type="nucleotide sequence ID" value="XM_066811877.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044937"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF19">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539438" description="Heme haloperoxidase family profile domain-containing protein" evidence="8">
        <location>
            <begin position="18"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="21"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8079744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="241" mass="25282" checksum="5B7A2D8E91C8AE2B" modified="2025-10-08" version="1">MRSTTAIIVSVAACVAAVPVNDHVWQAPSASDKRSPCPMLNSLANSGYIARNGLNISVSDFSTALLEVTNLDPAATKLVTAVGIKASTTGYADTLNLDDLDKHGVIEHDASLSRADWQNGAGDNHAFSKDLWADTLTHFPDDTISIKQIAAARAGAIARSKASHPDTFTYGAAQVQGSLLEMALGLAVFGSATEGNANKAHLRVLFEEERLPFEEGWVKPKNVITSADAQGLAAKVLAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCE6</accession>
    <name>A0ABR1WCE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007652</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667309.1">
        <property type="nucleotide sequence ID" value="XM_066811967.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045027"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053088">
        <property type="entry name" value="Beta-glucosidase/SUN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005556">
        <property type="entry name" value="SUN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31654">
        <property type="entry name" value="SECRETED BETA-GLUCOSIDASE ADG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31654:SF0">
        <property type="entry name" value="SECRETED BETA-GLUCOSIDASE ADG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03856">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046655383" evidence="3">
        <location>
            <begin position="24"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="432"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="343"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="487" mass="49868" checksum="F69B5C2D60B2FE4C" modified="2025-10-08" version="1">MKLSTLQATLGSVTLLLAEPTLAHKHKHLGRRNDHSQIHSRSAVAHLEDRGLACKFPTGEGLVPVSPNAMNGGWALSPDQVCFPGKYCPYACPPGEMMAQWKPFSTYATTDRMSGGLLCGLDGKASKPFDDKPLCTKGTGNVKVVNKCGKVTSFCQTVLPGMEDMIIPNDIQDEQVIAVPGTDYWDTTAAHYYINEPGVSSSEGCIWGDDSKPVGNWAFYVAGTNTDHTGSTFVKLGMNPIYEASSLASKKPTFGMEIKCTSGDCTGLPCRVDGNGVTSSEKADGAGGSAFCVATVPKGGSASIVVFNLDGSSGSDDKPETTSSATPTPTPTPTPTPTPTPTPSSTKETPTTTSTTPTSTSTSETLTTSTTSSTPTSSPTTSTPSTTPSPSSSTPESSTETSSSAQSSFTLLALGGIFKENGTATATASYTWTPSSATKPTAVATNGESAAGSAAPTESAKSESAGPQGSSAVVGLIIAVFAAACIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WE26</accession>
    <name>A0ABR1WE26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_008523</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668180.1">
        <property type="nucleotide sequence ID" value="XM_066812838.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045898"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05144">
        <property type="entry name" value="RIO2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030484">
        <property type="entry name" value="Rio2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015285">
        <property type="entry name" value="RIO2_wHTH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852">
        <property type="entry name" value="SER/THR-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09202">
        <property type="entry name" value="Rio2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="14">
        <location>
            <begin position="67"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="350"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8080705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="424" mass="47241" checksum="F7D6EA0790905AD3" modified="2025-10-08" version="1">MKLDTKAMRHLAAEDWRVLAAVEQGTKNHDLVPTAVIEKLSRLRGGPSSVSKSISALAKTSLIGKVKEAKYDGYRLTYGGIDYLALHAYAQQNVVYSVGTRVGVGKESDIIMVADHAGTQKVLKIHRLGRISFRTVKANRDYLRKSRGQGQGGSWMYLSKLAAMKEYAFMKALREEGFDVPEPIAQSRHTIVMAFVDSFPLRQVSEVGDPAGLYADLIGLILRLAKHGLIHGDFNEFNILIREERSTTKNETTGTEEETIKVTPVLIDFPQMVSMEHANAEMYFDRDVNCIKRFFDRRFHFVSTQPGPYFKDAKKTVGKDGARRLDAAVEASGFTKKMLKDLEAAIAEQLAGRGEEGEAPGTDGEEDEDDDDEGDEENDSDVSDEEDEPSREQDKAVQEYRQGSKTKEEPERIPIAKLSLGNET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEC1</accession>
    <name>A0ABR1WEC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008628</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668285.1">
        <property type="nucleotide sequence ID" value="XM_066812943.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046003"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045358440" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="30099" checksum="BA6089D78E293B65" modified="2025-10-08" version="1">MIRWLLPLCSSLLLLITLPLLVSAADDSKICYNRDGNFGPDGNNWKPCDPGADSSPCCGAKDYCMDNGLCLNADGNQFLTVQGCTSAKWDKCADICKDQRGKAGEPYEGDGVLLTFCPQGPEGYAKVWMCDMQVNAGMVKYCCGDYGCCNQTKNVGSIRIAKAVYRPPQAASASVSTSSTSASASASASSNGADQHAHDSNNDSRNLAIGLGVGIPMGLALLGGIIFLGLQVRKWTAVRQAQGATGNHGGGGVDNAQEVKRYDEPPSFFQRQELHDDQRGAELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFA3</accession>
    <name>A0ABR1WFA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7888 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008596</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668253.1">
        <property type="nucleotide sequence ID" value="XM_066812911.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045971"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057210">
        <property type="entry name" value="DUF7888"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40845">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40845:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25411">
        <property type="entry name" value="DUF7888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046931988" description="DUF7888 domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7888" evidence="3">
        <location>
            <begin position="60"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="20889" checksum="20267BBBC025BAB0" modified="2025-10-08" version="1">MRFTATNALALLSATASIAAATPTGHYSPNAGVAASAPEKRGEAQTLERPQQHVQKREILTAILTTVGTTAATAITTKAIEAASGLIKDLANFDNAREAFTKKTAEDMWAKNPDPAKFAAAVCYNEAYDLEDPQGMDGLTSAKMTLGPLNTDYDCFYMTAKNALYTRGDGGFINLAFVSDKRCTFDRDTADLTCTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL43</accession>
    <name>A0ABR1WL43_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668749.1">
        <property type="nucleotide sequence ID" value="XM_066809826.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042886"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046620345" evidence="2">
        <location>
            <begin position="34"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="322" mass="32801" checksum="E38C827CA9C891EC" modified="2025-10-08" version="1">MVGKAAADMTAPPSRRAASLFFWGAALLHLAAAAAAAAAQNDVCPYDGGWSLRVKSRYCPSSAPVDCGMGTQRRCCPSGYVCAGVGLQGGSWCCKEGEDCLSQARETPRCPNQQWTLWGGDTGTISDGAWCCEPGFNGFYRGKVEAVGCTDAGVNTLPGNTFFAKTVSTSQCATATPTTSSSSSSPSATGPTTATPTADGQNAGTSDDGDGNGGWDPAPSRASCQAAAAAQDMHNGSGSGPGGYAPNAYGQQQTTEMGYAPDSSVGGYSGSTAGGGGGGGYYDPSPSEPQMKENTVYSPPVELHNEHRHLMGDQRAESHEMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLM6</accession>
    <name>A0ABR1WLM6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005677</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668915.1">
        <property type="nucleotide sequence ID" value="XM_066809992.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043052"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="13"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="349" mass="37574" checksum="C37E09D29E4FD98E" modified="2025-10-08" version="1">MTNMKALVTAESGKVAVQEIPVPTPGEGEILVKVHYAAQNPTDWKSAGAAKEPGRVVGCDFAGTVAASNGSAWRDGQRVAGWVHGCSPKPPRGAFAEYLVTEASLVYPIPESVSFQDAAVVPLAFATAVQALFQRLQLPEPSKPAKSAFPILINGGTSSVGKYAVQLAKMAGLFVVATASKRNHELLKQYGADATVDYRDGDWVDQVRQVTHDNLEYAFDCISEKETTPAVAQCLSPTKGGHVMCILPRKTAELPEALQSKVRVESTIAYTVFGRPLKYGDFDNHGGETPADKAFWEKYLALLPEYLESGRVKPNKVKELGGLEDIPKGFEIHAEGKVSAEKLVYKIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM35</accession>
    <name>A0ABR1WM35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669094.1">
        <property type="nucleotide sequence ID" value="XM_066810171.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043231"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="108" mass="11138" checksum="9DEF42AB3AA06E17" modified="2025-10-08" version="1">MSSARRRPAGSPAVVDQQVAASGASGAVCAVDDGAVWVLLRGHGVLSGRHQVPRVVVVATAATQADHAFGLEGVALERHLLHDPPLRGTTERPAPTSSLLLFMGKGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMV0</accession>
    <name>A0ABR1WMV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006136</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669374.1">
        <property type="nucleotide sequence ID" value="XM_066810451.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043511"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="139"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="172"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="252" mass="26335" checksum="77BC2B7EC7976E15" modified="2025-10-08" version="1">MGVGLSLVAIASRCGHASATRKLVNGGAAVNSPDTKGESPIIYASEGGHEAIVRILLDAKASTESIDDSGDSPLLLAARGGHEAVVRLLLDKGANVKRRNKGGRTALIYAAQRGHGDVVRLLLRKLQKGADIVEVKDGRGESAMSAAARKGHEAIVRVLLEKGAQTESKDRAGSTPLILAASNGHGAVVRLLLEKGAKIDSVNRLGHSAQYYASKGGHKETAELLQRSRQARQGKQQAGLSGVQGILRLINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMW8</accession>
    <name>A0ABR1WMW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Chromatin remodeling factor mit1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_006125</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669363.1">
        <property type="nucleotide sequence ID" value="XM_066810440.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043500"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056616">
        <property type="entry name" value="Chromo_MIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041684">
        <property type="entry name" value="Znf-PHD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF17">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23615">
        <property type="entry name" value="Chromo_MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15446">
        <property type="entry name" value="zf-PHD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="885"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="1190"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="17"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="251"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1512"/>
            <end position="1715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="320"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="415"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="431"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1539"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1556"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1582"/>
            <end position="1600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1633"/>
            <end position="1662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1687"/>
            <end position="1708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8084854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1715" mass="190191" checksum="6B579C2EC3DA3AC5" modified="2025-10-08" version="1">MTANSFGDSEMDDLLFDLSEVGAAEPDAMEIDGTATEDQDILGDVNTGLQSPADDSIVYLGSSPKDHENTVPDPENDEPVADVQPNREETEKKRDVDGAQDSEGIEDLEELQDLVGQAQEVTPSRLFPIEVVLPPLEDPDSYEILPPSWTVEKVTRQVEQDGEVWYEVEFDDGRVDMVIISIDDQASLYTSPHIHSTSHLVSSLPVPHTSSRFLFYTVNVPGLRFWVLGTPLIATADYLLTTVPIPIHRTANQLQEQDDQRLASEQRAMAPRSAMERSFFEDDYSDSEGSGSDQPRKKRLQTRAPVRRSQRQTTSSRQASVDHRVHSGRDGHSDENSDGAAFDEDGDEHSTFRTRGSRAAATTSRRVTRASNSTKSKISTAYAQAKSSEDELANDSDGDTTFRPVVSDLAPTKRSSARKKKSVARYSQSRRRNDRDSSIEFETTRRSGRSAAKNYAVPDVDDDYVIYEDKPDTAAPKHVSVKEIFKPLVSDSDFAKMHSQECNVCQGKANSGKGALVYCQGCSYSFHKICLGIRSQRDHRVTKVGHDDFVLQCRICIGFYRKKDGNAPNHAKCQTCKLDNPSCSEFSTKKTPKQEEKLREENEGVDPITPLSSNLLNNTESLLFRCSSCKRGIHFDHLPPLTKDGEITSDIRADRLEEYAMVDWKCKDCVDAGNKIHALVAWRPVDESTYIKGQTCFDLTEDAKEYLVKWDGRSHSHDAWMPGAWVFGVAASAMRSAFAKRDTSLLPKMTTKDAVEEEWLLADVLLRVNYHKKTNNSHKAKDLARLSDIKDVYVKFQGLSYTEAVWDAPPPKDSGASWEAFCAAYEEFIEGAYFRTIPEHKMRERIQQYRSLDFAKECELKGIQPPGLKRGKLMEYQMEGVNWLLFNFHQKHNVILADEMGLGKTVQVVAFISSLVEDKPNCWPFLIVVPNSTCPNWRRELKQWAPGLRVVTYHGGKDAQQLAYTYELFPDGVKEGMKAHVVILSYEAAVEARTTFRSVNWAGLIVDEGQRLKNDESQLYLALQSMKIPFRLLLTGTPLQNNKRELFNLLQFIDPAHNAEELDAKYAELTKENIPELHQMIRPYFLRRTKLQVLKFLPSMAQVILPVTMSVLQEKLSRSIMSRNPQLIKAIISRSKVKAGERKGLNNILMELRRCLCHPFIFSDDVEDRTVTDPARIQANMVEASGKLLLLNVMLPKLKERGHRVLIFSQFLMSLTIIEDFMTGLGLAHARIDGSLSALEKQKRIDAFNAPDSPLFAMLLSTRAGGVGINLATADTVIIYDPDFNPHQDIQALSRAHRIGQKNKVLCFQLMTKNTVEEKIMQIGRKKMALDHALIESMDAGEDAGDDLESILKHGAQALFADEAQDKIVYDEASVEKLLDRTQVETTNAGSDESAESQFSFARVWANDKGDLDANTEEDAADDDTPAAGSVWENILKQREAEHQAELAATQQTYGRGARRRVNKVYNTNIVSDFIEGVNDDLLMEQQPQANDSGSEMEVDDELYIDGKMEESDDEYERIDGTDFTATQTKGPKGTKRSAAAPTTIPAIPSKKAKTDVNTPQSTNNTSAGAIVTGSSSSTAPKRGKPGRKGAPPNRHRQPAQKKGPAEETPTTGGQGEPEHLHPEPTVATPEQAATIGPTTTTEEPTNDATATGDDAAAVAAGGHDKPPSPGPDVEPTVNIQPEGGSSVAQFSGATTGECSTSHASTGSGEHADTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNU5</accession>
    <name>A0ABR1WNU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamine amidotransferase type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006481</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669719.1">
        <property type="nucleotide sequence ID" value="XM_066810796.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043856"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03766">
        <property type="entry name" value="Gn_AT_II_novel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051857">
        <property type="entry name" value="Asn_synthetase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937:SF1">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="4">
        <location>
            <begin position="2"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="580" mass="63774" checksum="D4F8252CF70C3985" modified="2025-10-08" version="1">MCGIHATISVARHTELSENLRQLLINRGPDHFGLVEREIFLPSVAPDLRIALNFTSTVLALRGDHVAKQPFQHSESDSVLCWNGEVWKFDDKVVSGNDGEAIFARLAQCDLGAATEDRQAHILNTLRKIQGPFAFVFYDSVGQCLYFGRDRLGRRSLLMREESDGQSLSFSSVADSPAAGWEEVQANGIYSVRLHPESSGEKPISLGHHISRHEWVETGGADLVLGVGSFNKDLPQGAEDQLDSASPCVSSLHHHLREALELRVLGIPEPPRPADHQSDVDTRVAVLFSGGLDCTILARMADELLPATQGIDLINVAFQNPRVAAQKQAAPKPGGVVTDDYERCPDRQTGRKSFAELKRACPSRDWRFIAVNVPYEEAMAHKARVVSLIYPHDTEMDLSIALALYFAGRGVGVGYTESAEFNPDAPMVSTPARVLFSGLGADELFGGYSRHVRAFEREGYPALVDELELDIARIGQRNLGRDDRVLANWSKEVRFPYLDEGFVRFAMSSPVWEKCDFGNKSHAADIEPAKRALRLLADQLSLPVIAREKKRAIQFGTRTAKLGSTTGRLKGTASISLQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP88</accession>
    <name>A0ABR1WP88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669845.1">
        <property type="nucleotide sequence ID" value="XM_066810922.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043982"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF57">
        <property type="entry name" value="PAAI THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="58"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="163" mass="17241" checksum="2882A0D483C84EF6" modified="2025-10-08" version="1">MAPKLPPLPFVRTVLKSFMSESGLEPRLFGPHLRITNAVPGKVDFELDITKDHTNRLKIIHGGTIASMVDLGGSLAVASMGLFATGVSTDLNVTYLSGGGKVGDKIQATASCDKMGKTLAYTSVIFKNAKGELAARGSHTKYVTQAWKSQTGEPFTTPDGSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPB7</accession>
    <name>A0ABR1WPB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669873.1">
        <property type="nucleotide sequence ID" value="XM_066810950.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044010"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="94" mass="10255" checksum="ADE88A0B9DFD4ACE" modified="2025-10-08" version="1">MSYYNPNWPNPPPQPFQFNPAASTFYPQSFLPANPPFNTYQPTLSNGVASPWVVQPGSSSGWGGYSVTGLNPAGQHYPPASWPAAYPNPNTHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ37</accession>
    <name>A0ABR1WQ37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_006858</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chitin synthase family. Class III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670096.1">
        <property type="nucleotide sequence ID" value="XM_066811173.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044233"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF11">
        <property type="entry name" value="CHITIN SYNTHASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="560"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="619"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="652"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="698"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="729"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="830"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="864"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="14">
        <location>
            <begin position="917"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="12">
        <location>
            <position position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8085587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1074" mass="120724" checksum="3BC49207C1108B6F" modified="2025-10-08" version="1">MAYNGHPNDFEGHNLQDMPANSSMMMRPSGICLAAMPLMHMTKIDLVPALPSPPGLRLQSYRVLRPWSHNHTATSGLQHRVRWPGGFATGQQLEDTGYGYGRPTSTVNGEDAWVRRQQPGGGGGGGGGLGRSKTRRVKLVQGSVLSIDYPVPSAIRNAVQPKYRDVEGGTGEFVNMRYTAATCDPNDFTLKNGYDLRPRMYNRHTELLIAVTYYNEDKVLFARTMHGVMQNIRDIVNLKKSTFWNKGGPAWQKIVVCIVFDGIDKADKDTLDVLATIGVYQDGVVKKDVNGKETVAHVFEYTTQLSVTPNQQLIRPVDDSPQTLPPVQMIFCLKQKNTKKINSHRWLFNAFGRILNPEVCILLDAGTKPGNKSLLALWEGFYNDKDLGGACGEIHAMLGKGGKKLMNPLVAVQNFEYKISNILDKPLESSFGYVSVLPGAFSAYRFRAIMGRPLEQYFHGDHTLSKILGKKGIDGMNIFKKNMFLAEDRILCFELVAKAGSKWHLTYIKAAKGETDVPEGAPEFISQRRRWLNGSFAASLYSLMHFGRMYKSGHNIVRMFFFHVQLLYNIAQVAFTWFSLASYYLTTTVIMDLVGTPTAGGPSSQLHHGWPFGDRATPIINMILQYLYLAFVIMQFVLALGNRPKGSKWQYISSFALFGFIQLYILILSGYLVVNAFSNSQVNFEDDLKQLLTGQSQVAIILLALFATFGLYFVASFMYLDPWHMFHSFPAYMVLMSTYINILMVYAFNNWHDVSWGTKGSDKADALPSAQVVKTDKNEAAIEEVDRPQEDIDSQFEATVKRALAPFIEVEEEEAGDIDDSYKAFRTSLVLAWLFSNAFLIVVLTSNSFNTFGIGGTTTKRTAAFFQFLLISTAILAVVRFIGCVWFLGKTGLMCCFSRRKRSSKRRITMKLLPGARRRRLPLRNYESKKLSLGSTMTTEFPDPDNILEFILTITPDEGQYTGGKFTFSFNMSPSYPHEPPKVRCQQKIYHPNIDLEGKVCLNILREDWKPVLNLNAVIVGLQFLFLEPNASDPLNKEAADDLRQSRDNFRRNVKNSMAGGSIRGVQYDRVLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQZ6</accession>
    <name>A0ABR1WQZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670411.1">
        <property type="nucleotide sequence ID" value="XM_066811488.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044548"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="238"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="285"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="410" mass="44988" checksum="F739AA251B142610" modified="2025-10-08" version="1">MSQATTASPASSPEQDETADLHVTSAAPAIIEWKHDGDDAVTVLSDPDPRSHHITFQMRHLHDPEQPAASFALHIPAKLKARPATPRSSSSSLPRAFSRSIKSRPPVDIVVPAEVPVAPLRAHKAATGQVLDLLPSLGRVTRLVLYVPANAFPKHKLDPICATIAEGRLDPTDRSDDLASLYSGSGGQILRFDDPDEAPPLYDDVPPSAPMAPILPEASSQGMLLMAHLVPIIMTNRPSTASLHKNSRKRSRRDRDSGGSVEEGRSRCCSSDEVMMALVAMRKQMAMQEDRMSQQSRRIDELEHQATKYQAELDGAQKQTAQLRQELDDAQEQIALLQGRVEVVEQEDLGRLDQEICGLREDLDALQEIEERGFDSDAENRITDAVTERVTSEMMDSGVAYNATVTFSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WSA3</accession>
    <name>A0ABR1WSA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">sterol 3beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.173</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Autophagy-related protein 26</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_007060</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a sterol + UDP-alpha-D-glucose = a sterol 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22724"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15889"/>
            <dbReference type="ChEBI" id="CHEBI:37424"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.173"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:22725"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ergosterol + UDP-alpha-D-glucose = ergosteryl 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61836"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16933"/>
            <dbReference type="ChEBI" id="CHEBI:52973"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:61837"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.173" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670298.1">
        <property type="nucleotide sequence ID" value="XM_066811375.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044435"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13215">
        <property type="entry name" value="PH-GRAM1_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13216">
        <property type="entry name" value="PH-GRAM2_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048066">
        <property type="entry name" value="ATG26_PH_GRAM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048065">
        <property type="entry name" value="ATG26_PH_GRAM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF25">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="12">
        <location>
            <begin position="327"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="90"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="497"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="663"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1235"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1388"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1444"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="525"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="570"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="602"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="630"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="685"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1247"/>
            <end position="1261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8085789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1470" mass="164415" checksum="4E684ECED479100C" modified="2025-10-08" version="1">MAPSPPDITSSPHTEADAARPRSSKKLQKKHKEESNRRRTMELPNHLRDADDAGEEDIIAANGRPNGMFMHMNQSIFDVFSAARSTANIHGRFEDQSSDEEDEDEGGADIRDLSRNDSQPEAKGKGKETETPVDSMSRSRIFKKSASDKSSSSDKDSDKKHRRRISSNLLRSLPQLTRLGSLSKSKSSKSSKSKQQTMDESSPDESSSPTRRHSEPESSDSDAGTPKLAPVMSRILEARDEMSARPSFDMERLSSDLRRTALSDDSGDGGPTKLQLALKDIFELDQAEEVIGEYPCWLLLSVLVDGYMYITSKHICFWAYLSKKADKVTKDGYMAKSGKRTSKYTRYWFRLKGDTLSYYHDASNLYYPHGQVDLRYGISAEITDKGKEGVNFSVTTNHRTYYFRADSASSAKEWVKSLQRVIFRSHNDGDTVKISLPIANIMDVEETNMDNLGFADTVKIRVIDNDETFAIDEYFFSFFNSGEAAIRLLKLLVGDSTDSDNESAAAGPLRVPKKRRDDTARPSSKRSSLSLNTSRMESSQVLSPKFREPVKATLSPMSPTMPRENTIRASGDHVRSSSDAMKKFDRRSLDVDTIARDHSPRRSFSGQRTVSSSRGKHAKAQSDNHEESDSFAQSTDDPSLSNMIASSIEDPSASQILQGSEVFHKPTLHRRSTSMSRRSQQENARSGKDRTKHAEGYPHPQHAATTGHVVDPGSGEGQAGQAPTLQNIAKMGAYPLQRAGHFAGYLNRTSRQMGNLLATESMGYVEKVSGMWKGGRKHYEQSTALNPEDSFQDDEDETDVKAANERFHSHFLLPESDKLQATYFCHMLNVLPLYGKIYLSQRHFCFRSLLPGTRKKLILPLAHIETVDKEKGFRFGYQGLVVIIRGHEELFFEFAQPVIRDDCAVSVLQNLDRSRFIRESQYFDSDDMKKANDALAEREALNAARLKEFPDQDQLPHQLTMLNDGDGPTILFDDAKDSLVHFQPTKSMKITCLTIEFRGWIEGHDIEFAPVAGDPGELMKLVIEYGTFSYGFFKEATSSFRPWLDGLLESAWEACKGTDILIESPSAMAGIHIAEALYIPYFRAFTMPWTRTRAYPHAFMTADRNMGGFFNYLSYGLFENTMWQLSSRQINKWRAKFLNLPATSLDKMQPNKVPFLYNFSPGYWFLDEGKNWTPPDDLRQFIEKAREDGKKLVYIGFGSIIVPDVAKMTQEVIDAVQGADVRAVLSKGWSDRVTKEKGVEAATDAPDQPKDQPEDQPKEPELPPEIFQISSAPHDWLFSQMDAAAHHGGSGTTGASLRAGIPTIIRPFFGDQFFYGLRSRAPRCWDLHEEVGAISFAKALWKATHDDRMISKAKVLGQSIQQEHGVDNAIQFIYSKLEYARSISTEKSKMRKPVASSATGPTEHSDGPELYDDDDVEESWTFVAGDDFDPDIVKKQVISQAEAGAVADGQKAALGSRQGSNRGKAGSVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WSB0</accession>
    <name>A0ABR1WSB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670297.1">
        <property type="nucleotide sequence ID" value="XM_066811374.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044434"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="66" mass="7416" checksum="A6883BFC139CB871" modified="2025-10-08" version="1">MTNAVYPIRFKSTVRCNQPPGIVGSLVKVEFLNGQVSDAEDHFVIRLQNLFNAFQQRVHIAGRSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXS4</accession>
    <name>A0ABR1WXS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Membrane bound o-acyl transferase family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002932</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the wax synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670865.1">
        <property type="nucleotide sequence ID" value="XM_066807247.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040307"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF67">
        <property type="entry name" value="WAX SYNTHASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="9">
        <location>
            <begin position="319"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8087971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="53627" checksum="5BAB570AC49670F8" modified="2025-10-08" version="1">MVAYSTSGNPAMGYGCGLIAAWSTIHIFTLLVWTRPQWDAKRVERYTRRTTPETNGVLQGNGHAKQASEANGNGVKHLNGHANGHASPTTTETITANDAVASCNGHATNGHVPNGLRERHPADAEKLRQRSLEPVPGSYDGKVGLHQQEYFYKWQEYPEDAPFRTRFNWAFDIATQMRMTGADGKTQEPLDAIPNSTPEGYVRYRTRSEFILQCIVTRLIPCYLVVDLCATLMTQDPYFILGPEHNEPLPANLASLPAAAPRTPAHCYLLPGVLFAIDLAFSAGQLALACFGPLVLGFRAHPWHMPTANGSFVAGVLDRGLEGFWGQWWHQTFRFGFAAPTNWLVREGYLKKGSPLHAFVGAIVAFGLSGFIHAMGSYSTVRYSWPWDPPVFFMLAGAGAQIQRTLARHILRESIQTYAPRWLRRTGNLVFTFAWMHMISSYLLDDFSRCGLWLWEPIPFSFARMLGLGTPGGKWWRWGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY52</accession>
    <name>A0ABR1WY52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Homoserine acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670983.1">
        <property type="nucleotide sequence ID" value="XM_066807365.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040425"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF15">
        <property type="entry name" value="HOMOSERINE ACETYLTRANSFERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="39"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="341" mass="38127" checksum="F20D2C708303AD80" modified="2025-10-08" version="1">MPETKYFHKGLTLSARSEPAGKEFPAKLAYWTFGSPSNPAVLMPTCFGGDLEGTMPFLYSNEDGNSDPPFPPEKFFVIVVGLMGGGESSSPSNQPPPFDGTRFPKLSYEDNIRLQYAFCTEELGISKIFTYIGFSMGGQQAYHIATLYPDFVENIVGLATSARTSWHNWSFLEGPKHALITAHDFHGGSYEKPAVDGVKAFKRVYATWALSQGWFRQQCWKEAGFDTLQDYLKARWTIGPDANDLLAMLWTWQKGDISLLHPEDGGDLAKTLSNIKARCLIMPSRTDQYFPPEDNEEEVKHLKNGELAVIETVWGHFAGGGIGSKQDTEFIKKVVRRFLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYC0</accession>
    <name>A0ABR1WYC0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase family 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003122</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671055.1">
        <property type="nucleotide sequence ID" value="XM_066807437.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040497"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF123">
        <property type="entry name" value="TREHALOSE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1010" mass="113242" checksum="633B502301EF33B4" modified="2025-10-08" version="1">MIGTNFESSCFPSGPASLNRSSWRNRTRPPLKKGRLDEILQTEEVNSPRPALLNRAESELPAHERASNTNVPVTPGIHLETYHEDDEDKKARSTSPNYFTTNPANPQTPGDNVLPGFTEGATEGTMSDQAVLRRMSLASKGRRQSISQIKDAVPELALTGNIISAAFNLPYALKYRQSGDWELGSRRGQSALYDAFSYLSSDESPWNHTVVAWTGEIETPYNPYSPPGTPPEVTANIPGKNVLSAPIPVDTSTPPTPAVQDGTFIPKEHQLDLEQQLAHDKRIKTVPVWLADDDEMSDEGITLTDQNRWRRYADHELYTLFHYKQHEPTDGRSERIQWADYYRMNLKFANKIIEIYKPGDVVVIHDFYLMLLPSMLRQRAPNMYISFYLHSPFPSSEFLRCLPRRKEVLEGVLGANLVGFQSYSYSRHFSSCCTRVLDFPSDSIGVDAYGTRVEVGVFPIGIDFAKVEQLAWSPSVTKAYESLKTMYQGKKIIVGRDRLDSVRGVAQKLMAFERFLELYPDWAEKVVLIQVTSPTNIEEDSENKIASRVNELVMRINGAFGGLTFSPVQHYPQYLSQDEYFALLRAADIGLITSVRDGMNTTSLEYVVCQRDNHGPLILSEFSGTAGFLRDAIHINPWDLSGVAKQIDNALTMDGKERESMQKPLYNHVAQQNVQSWITKFLRKLVSNLANNRNASATPLLDRTELLARYRAASKRLFMFDYDGTLTPIVREPSAAIPSERVIQTLQTLAADHRNDVWIISGRDQEFLQQHLGHISELGFSAEHGSFIRHPGETVWENLAEKFDMSWQEEVVAIFQKYTDRVHGSIIERKRCALTWHYRQADPEQGVHAARECQKELEASVAKKWDVDVMEGKANLEVRPTFINKGEIAKRLVNDYNKDISHVQGSPSSDPSKLEFVLCMGDDFTDEDMFRALSGLSGTALEPENVFTVTVGASTKVTLARWHILEPADVVEATGLLAGAGSSGRNDDSTVLSSVNLAAVAGLEGRVPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYL7</accession>
    <name>A0ABR1WYL7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003217</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671150.1">
        <property type="nucleotide sequence ID" value="XM_066807532.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040592"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="52"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="258" mass="28580" checksum="BC93D4574977B4C5" modified="2025-10-08" version="1">MASHTTLPSAAAEGFKDAASYDAHRPSYPPEVVESFLEALKITGQPDMNIVEVASGTGKFTELLAGRPERFLIKAIEPHEGMRGRLAEKDLSAVEVVDGTADKMPVSNDWGDACIAAQAFHWFATPESLQEIHRVLRPGAVLGMIWNVEDYTKKWKDVFQQQLPGNPLQALADTLTNQLPRFSLPIGEKTSKWTVWLTEDALWSRLSTLSQIAVLKGEEKEAAVKVFKEAMQSDDVERNGDGEIALHGVTYFAWTDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYT6</accession>
    <name>A0ABR1WYT6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylethanolamine-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671219.1">
        <property type="nucleotide sequence ID" value="XM_066807601.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040661"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF85">
        <property type="entry name" value="INHIBITOR (TFS1), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="216" mass="23193" checksum="D5916947ABF61287" modified="2025-10-08" version="1">MPTPSAPPLQSAGLVPGPATALLPASTDWRPTTQLHVAFGGEDVELGTFFRAGECKSTKPVVRFGAPASATPLPSAAAAEETTEQQEKKKRNKRRYTFLMIDPDAPTPDDPKFAFWRHWVVTGLSSGGETGGDCADTGNEVTEYLGPGPKDDSKPHRYLFLLYQEPDGMQALTKADVGGDEFVQRRSFDAATFAARQGLVLVGMNWMTCAGDGWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZV2</accession>
    <name>A0ABR1WZV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003644</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671577.1">
        <property type="nucleotide sequence ID" value="XM_066807959.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041019"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057246">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00132">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046812835" description="Peptidase M14 domain-containing protein" evidence="9">
        <location>
            <begin position="17"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="10">
        <location>
            <begin position="123"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="8">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="451" mass="48858" checksum="016B75038D22C79C" modified="2025-10-08" version="1">MRLLEVVLAAASLASAAVTPSPDEQVVYDGFKVVRVNVTDGLPSLKSKIASLAQTLELHSYADHMDVALAPSDVAAFEALNLPSDILDEDLGASIAAEGPLVSFNSIAEVGANALPSDSWFNNYHPYSDHLQFLKDLQSALPQNSEILEIGASYEGRQITGLHLWGSGGSGSKPAIYIHGTVHAREWIATMVVEYFAYQLVSGYGNNATIKGFLDSYDFYFFPVVNPDGFSYTQSNDRLWRKNRMPRSSTSAKGTDINRNWPYKWEVSGGASTNPSDEDYRGQAAGDTPEVKVLKAFTDKLAAGKGIRLYIDFHSYGQYILLPYGYTCSKRSSNDAKQESLAGTLQAAIAKPYGKRFTYGPICSTLYAATGGSTDVSDIASFPVCTLIGKRKEPLTRLLQYMTDVAGTTYAWAVELRGGGSGSSGFVLPPSQIRPSSIEIWQGMQALIPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZY3</accession>
    <name>A0ABR1WZY3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671590.1">
        <property type="nucleotide sequence ID" value="XM_066807972.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041032"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="249" mass="25529" checksum="DC9C0D7FCBBCF2B3" modified="2025-10-08" version="1">MAPIPVYTNSPVATKPDGATPQTAAPDASGSKKETIPAATTTSQASYPQAQPGAAPSLPIQTMTPQAQAPPLQATPTQPLGTQGPPAPQPGAAPTLAGTTRHLPPPPKAGEKYVPPPPPTTSQAASAPYPQQMAIPPPTMAYPAQQLGTATASAPSSAYAQAPTGIVGQGGAQSSLDHPPGYHQNVNAVGLDQYQYQRQAIARNESADRRQQDGTEEEGVWGAAKKWAAGAGEKLAAAESEVWKRINKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZZ4</accession>
    <name>A0ABR1WZZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS drug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003708</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671641.1">
        <property type="nucleotide sequence ID" value="XM_066808023.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041083"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF81">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="554"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="88"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="585" mass="62513" checksum="A893266BAB080E48" modified="2025-10-08" version="1">MAGLTEPGTAASRLSSHGDGNVELRMRDSLDLESQHRHSQDSTDDDEAAQNLLGPSSEPCPGDDGGGDGNDAQAHHHRWTPPRNFVWIQVAIMSNVFLYGFDGTITAATYAVISSAFGATNTASWLTTSYLVTSTAFQPLYGRVSDLFGRRVCFFFATVAFALGCLGCGLAGDIVALNCMRALAGLGGGGLMTMATIINSDMIPFQKRGMYQALQNGVTGFGYICGASLGGAIADTIGWRWCFILQVPISVFAFVVGWLAVEDPKVNLIIGSKTLKETWHVVDFSGALLLVAAVSVQLVGLSLGGNELPWSSPWVIGALLGSLVLFALFIRVEKRTKAIPMIPLRMLNARLPILIQISNVCAGASAFAFLFILPLFFQIVLLDSATQTGARLIIPSLAVPIGGLIAGIVMSRWGKLLTLVRVGAILMALGNGLMASLRFEDSYWKYFVYIFPANLGQGVIFPAILFTSLATFEHSDHAVSASTVYLIRSLGTVWGVSITSAIIQTTLSVRLPEALSDVPNKWTVIDDVRHSVDALLRLPPDVQLKARHVYYAGLHYSFAASSACAVVALCAALAARAKGLRKTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0H1</accession>
    <name>A0ABR1X0H1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671802.1">
        <property type="nucleotide sequence ID" value="XM_066808184.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041244"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132">
        <property type="entry name" value="ALPHA- 1,6 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132:SF29">
        <property type="entry name" value="ALPHA-(1,6)-FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="594" mass="66494" checksum="933686FFB7B3360F" modified="2025-10-08" version="1">MPPPALDLTHSTHAKMMVIPPRLNLRRAASYTGTSTNEKLQSFTLLASAISWPSGLGAEAQEIPGSPRPSRVFRVFGWFLSIVAFMYIAKAVVKHFGEVPVVVDWALGAQEEYEMVGQDELPEFPTPIAVTDRRGRSKWTVFPLTTKEYADICAKCHEVATHVRELHGKSYPSQKAGLNYYYQDPYFLDVNEAEQRGLLPGTQDRTWRISPRAQEGHLVGESKSTLVDQPVCGSSLTFVLETPDAGLGTSLMMLWMAYGLAQKEKRAFFIDDSRWAYGEYTGIFKAPPVPRCQSPPRHEMLPCPRHARHLVVSAATVKETFGNSFANEYEDRERPMFDLARTGYEALFHLNHDDHSYVTSRIIELRKKAKAPQGHKHDGTVVGIHVRHGDQHPFEYQYRGAYIPLNLYADKAREIIEDLHNTSAPSGGENVVAKQHSFTVIASDDPEVYDSEEFKRSPRAQEMIKLAAKAQTPQPEQDRHVMHKFVEETFGWEGGFFASMFWNLGRSGINSDSAAASMPVTPSAETTRLRSFIGRAYLMDLAILAHGSDALICTISATGCRLMAVMMGWEKAINHGDWVNIDGNYQWAGLTPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0Q0</accession>
    <name>A0ABR1X0Q0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003938</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671871.1">
        <property type="nucleotide sequence ID" value="XM_066808253.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041313"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="101"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="167"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="201"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="234"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="35492" checksum="3A1FD1A2D22F67DE" modified="2025-10-08" version="1">MAHYFADDYASDEEKARLFQHGSNGEVVDMITLVKELAEREGVTTVDVIVRTQDAQGQHLGHHCARGGTAHCRAALVRCLMEFTSSQKTLQWVFLDGGDRAGNSPSMIAARHGHALMLTTLATRGAFIHLRNNAREGILHQAVQAHSTETLETAFALGAEPDSLDAQDQTPLHYAAYYNDLEACKILLGNLACPSAQDKLQGYAALHVAAKAGYADIVEVLLANDAYPDAESKEGTTALHLAATGGYSAVVTLLLGKGANVNAQDSLCRTPLHAAARSRQEGALGCVELLLASSHVKLELKDSTWKTAEELAHGQEHVLAAFKRMSNLNCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1S2</accession>
    <name>A0ABR1X1S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vps72/YL1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004344</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS72/YL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672277.1">
        <property type="nucleotide sequence ID" value="XM_066808659.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041719"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046757">
        <property type="entry name" value="YL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05764">
        <property type="entry name" value="YL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="3">
        <location>
            <begin position="592"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="255"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="656"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="792"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="353"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="395"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="492"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="514"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="538"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="675"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="686"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="721"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="763"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="798"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="822"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="835" mass="89106" checksum="42EF30E57B1AA7AA" modified="2025-10-08" version="1">MATEEGNQRMSLDQNEDADSLDSSSEDGDAPEATETEEQPVEWLATSRAKRSTAGNRMQSMLAVEEPDDELELLFAEDGEDGGFTDVDEDASDVQMDSSSDDDDAHENADEDEGEKELARQARESKQAARKRKAQEAIPLKFRKKQGTAASADVGARGETSQAGRRNGAQGQEDGGPQKPPMTQAERLAEAALVEKRNAKSLNRWEEAEKQREAERRAKLAALNNRQLSGPVVTFWSGVGEWVDGKLKYVGKIVTIEEKPAKKKRTSTAGVDLPAEPPSKDEEGKEAGQKAEPEVPVQTTETDQVPVAETGPESAEPKEKPAPAEKEIFDLPIARLPSQPKDEQPFRPKDLPQHPQEPQPLQNPDSPDPKVTADEIEHRDQARPSSEKPMQSKPAELKAPDIKPPDMKSQEPGVYTTSMFAPPSQLPVMKPPEMKPPTNSFLAPPQGPHKVGYLCQCWAIPPRQSPLAAPQPDTRPSLAPPAASAPTPPQPQAAQKPSALKAPTPHAPPPPTKTPSSSKPVPSHTGRSKGHAQKEKASPPPRPPTPPPNGKATRNCILLQNFNENAISQKAVQTRILFGKEMQKLAKPGPAPRCVITNHLARYRDPETGLPYYNSYAYKQIQKLKHGDYKWSQLVGAWVGSGSLAATGVPARFLDPTAPAPPKVEAEQPAVSGGKKPEEASRGKPGETAPVTPVTPVTPTGATPSNPFWGGSGQYSYTSSPATQPATKTQAQAESSNHPAPPAPVTEKIIPVAEHSATKDANSEVVSVSSSANAPVGPGLVHSVASPVGAATSDAFKTSPTSTPVPVSTSARETTQEGEALSSKSTAQTTTAVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X204</accession>
    <name>A0ABR1X204_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004377</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672310.1">
        <property type="nucleotide sequence ID" value="XM_066808692.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041752"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790:SF4">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01111">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045832473" description="Cyanovirin-N domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanovirin-N" evidence="3">
        <location>
            <begin position="25"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="687" mass="76760" checksum="A9B7C810403AF0BC" modified="2025-10-08" version="1">MQTFQILLALCLGIMSVVADSSSGNFTSNCPYWYLSDSGNVLTAKCNNDNWMPTCSQLDLNKCLENKDGALSWAASGKAFSNGCSSCKSTGYASIQCTCLSSDGKSSVNSVKDLNENIHNHDGYLGCFNFQGANCTRRASSTLSQSGGMSQETSHKSEIGNQALSVASLTIPTIAALDAPHPNQAVTQRNAGSSPLLKLPLEIRIMIYELATHVDDPIQPWQMAAGSNKFFWVGKAIQARNGLANVPGQSPIENLTVNELARSCRKVYHDLEAKPVFYRTNSFQFGGVEVLHAFLAAITPARRGSIRRITIEDKDPNYSGRETWLARDGSYGRVMPLLLQCNDLRQLTLRLVPVYTHPWRYHNTEPVEIVRYELNAFSQWLSESPYTTDTHSLMDLPSLQIVYDRHFWRGHLPRDRWSNDITIGPYWDVSAIRGSLAEDVRRALGAKITNIKKALALRKTLISQNEHKLKVTDEQLMESIAAAGIHFPGEDRLHLNRLDSDIGAVSSRTRNRCDTTNFNAFRGRIERPIGKYDSEGLLMELFSILDIRSVDLDIECRITVSYEDPLFGKVEATLEPIHAVLTEDGIRQLQALNGIKLRDAVKDRQVMQSLPAPQDVKCIADAYVEGPVHRPATLRRAYQNKWAALQKKFEARVKKWAPKANKNEAREQEQEEKEKTKQAAKPATHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X251</accession>
    <name>A0ABR1X251_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004459</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672392.1">
        <property type="nucleotide sequence ID" value="XM_066808774.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041834"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24142">
        <property type="entry name" value="ACL4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="256"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="319" mass="35238" checksum="DD0E155718EF4633" modified="2025-10-08" version="1">MLWSWRKKALSQSQTGSDSALAALNLLGQINIEIGEFEAARASFLKAVAIDQDGSRSDETGGGPEKFLCLAQLSEEGGQDSVKWFEKGAAALKAQIQKYDDLKKLTDEQEIMVDELRQKHAMTLCAVSEIYMTDLSWEADAEARCEALVTEATMVAPDFAETWQTLASVRISQERFDDAKAALIRSIDLWKDLPTGDPSVPDFPSRVALARLLMEVGMEQEAIEVLERLVGEDDHSVEVWYLGGWGLYVMGEKQKQQDSTEGQQEYEDERLGDHANELLTAVSKDLGDVPSDDEDDGADGADGDEVWEDEDGSDEEMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2M0</accession>
    <name>A0ABR1X2M0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672557.1">
        <property type="nucleotide sequence ID" value="XM_066808939.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041999"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="195" mass="21113" checksum="6142FDA518A96336" modified="2025-10-08" version="1">MGSDRASGLAAQRSHAEELPDGPGLRALDLGLAFKLLNPPPLLGRNTPHPPKTAIARRPADHRSSQTGEFLQRVRNAFISPALVPSYQVPRLPLVPSILPHPHPHPLSTTHYPPASQPTPHLTCPPVPSQLLIPSQTFLVTPTAPFDKASSKLLYRNLQSVQLQDSETWAQHPMRNLHDTWAQAVVVAVAAAAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2T9</accession>
    <name>A0ABR1X2T9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Elmo ced-12 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004697</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672630.1">
        <property type="nucleotide sequence ID" value="XM_066809012.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042072"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024574">
        <property type="entry name" value="ELMO_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11841">
        <property type="entry name" value="ELMO_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16457">
        <property type="entry name" value="PH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="2" id="KW-0581">Phagocytosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0729">SH3-binding</keyword>
    <feature type="domain" description="ELMO" evidence="6">
        <location>
            <begin position="223"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="230"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="557"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="694" mass="77387" checksum="35B1728A8C02E940" modified="2025-10-08" version="1">MDQADIPALLSRLASDEDAARKMAVFKLQSSINDPSFADVFISSGGLVILRRLIMGTGGNTLAYSLQSLTRLLEVDMGWDIFEGPTAGELVERIVELIVMNPLVNILRGAMSILVALFFDLVIQQLDSADHALCANALMLINSLIRDAVSTEPSGNGSNKNASEEWPKFIKRLQDLGLIKAVYNLMQGSALQDLAHPLLEFQSLTKMLLRKWKELRVDLERPEHRRALKGLHLASAPSRDHLNGTVNGDDAPEPSSKKGSRKHNPEKWRRLGFESENPAVEFEGAGFLGMMDLTDYVRKNEDGFQKLLLEQSTRPLTERCPVARASLSVTQTLYDQFDCNKTDIEDLRGYQLSDTRHQDKLFRPLLLQWSRLHTAGLQAFFRLWKATGAGQGDFEKIVELVRILMDQVVGSSGRSKDVVDVEEDLLEYDLARLRELQMDLLEMSFEENWGQHLYQVREDLRNESLSFVKEQRVRCLLQGSWFSKPAPRKESLGANLQAARAAHSTPWRYAKLSHNRRYLHYADFALRTELDPTLEALTEKIDLSKISSVVSNVSVINDDEKSNTQTSDTSGPNTSTGSMGAASASKTSTKITMFGFTSAEEALRPTGDGKEQPLLTLYPLNNSLASEWLDGMLMLLEQAPLTADTTKLVTLVGEYSLKIRLLNVGMEAAYGGPPPGAGVVPSRQGLDDDYYYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X391</accession>
    <name>A0ABR1X391_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clock-controlled protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672771.1">
        <property type="nucleotide sequence ID" value="XM_066809153.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042213"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038843">
        <property type="entry name" value="Sed1/Spi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523:SF1">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="21318" checksum="621C423BF0B2B363" modified="2025-10-08" version="1">MATFFNLVSRCSTLSPSPPAAGASAAVYQVAPRLPLPAPALLLLSATYPVAAASTSSAPAATYPVAGTSSAPAVETKSTAAVETTSSAPAATYPVVSSGNGTTISSQAVKYTTEVVNQYTTYCPGPTQITHGTKTYTVTAPTTLTITDCPCTVSKPVYTTSPPTYNNGTVPVVPGKPTQEAPAPTGGYPTKPTQATTPVAAFGGLLGLVAFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3A7</accession>
    <name>A0ABR1X3A7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672718.1">
        <property type="nucleotide sequence ID" value="XM_066809100.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042160"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1408"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="591"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="769"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="831"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="857"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="873"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="903"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="976"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1113"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1206"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1261"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1299"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1323"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1360"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1385"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1421"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1496"/>
            <end position="1507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1566" mass="168599" checksum="F5B932BACD376C96" modified="2025-10-08" version="1">MAVAENDAPAGDITDPSTHDGPKTPIDISDVKEDSGGSKKGKKNKKKKRQSATESLDPPPEAPSRAIEPVEEPLSQTFPSVEQPIEPEPIAVAPEPSSYIEDQPVERQDTVDADGAASMAKKAKKSQKGSQILNDLGETAPSVEEPMTESAKDDAVTTQEDVAFESTPAPMTNADEAQPEEEWAPVKRSKKDKKKNKASSDETSSKEVVADDEWSAIPSKKSKKKKAQASLSDEVEEKSADVAVEPTPEEASEQASVSVPEPALEPTPEPEVPPPPEEVVEPGDGVDAAPATPEKSKKDKKRRKSVTFADSAEEQPMVSLENVQDDVANSGPTDETVPADLEAKPEPVAFSDVPIGESSSSRSLENKGEQAQSVPSSEPLEVLNPEPGESTSQATTNKDISAVSPDDEFPTVTKKSKKDKKKAKRKSQEQELDITAPEMSAALDETVSTTGQPAEIPQDVGNSSAITQDESTPAQAIAETTVVDEPEQVKAEESIVEVPSERPQSPSAAPEAIDKPSAEIRDLPNQDNPNIDQPLGHSTDTPAEQSAEQPIEQPEEQPVQTHDDEFTVVPTKKSKKDKKKKKSSQAQLPDSSSVETSTEQQSFLAPGQPSEKEPSATEPWVTEDIAGPSEEQPVEEHTNQDGTIVADKSTLKAGLETSEVAHEASSTLAEPASVGSNITTVPVLQSTPEDQAKQETLQQDRALPEQTNTQDTVAEDEWGISSPAKSKKDEKKKEKGAELTSEEPLIAPTEEASAPSSLVEAPIEVPLSEGTSLDQSTAPSFEDKSGAGPSEELLVSDRPEPEVVSPKKSKKDKKRKGRRALDEVVVAEAPPGEHKEADVLSADEKKDESLPEQAVDAPRDKPKEAMEDFAPVKKSKKEKKKKRQASPWEDEVLQEAAPEPSEMASTTVEASPSQPIETSSESANKFLSEAVEEEILPIAETPKDEEVSLEGPSQHPPVSGESFDTKAVEATPAPDDVQREATADKETESQQAPGTTLPAESDTKEVTEDAFPEYTSSKKSKKDKKKKRSAKLHDDPESVPVTTVEESVPIQDPRDAPLATDETVAEAVVSEEGLKELDVKKSTEDVTAEESLSATDRFNPETERSESAASKKSKTDKEAPREQDEQEPLPSSLPTVAEPSTAQAQGQGPVDIPIHSEKFPNEPMPAEPSKEPLAEEQSVPEEQPALQEHPLPQDASVSKKLLTYPTLENTATKGSTVPSDDLIDKEGSDTANATPQALVDQPRGLVHSLGDQTAGLPEGGQPTQEQTSANDLATELRVDAPTQPQVEDMMASKLPIRVSSRTVQTPASAATPDGPASASRRPQRPEDAIEATERELQSEVPNEKPVGADASIAEQDTVPRDSSITQQIETIPTEDEWADSFNATKSKEDKKKGKGKFQLELERILSRQVTSRQVPVNPKGARTEVTERKQIDPSEELPTTPAAAEWADNGATEKDTAILEPEPASWEQMPDTQHSLATQDIVVHDDTPKALLPEPATDDLLPDEPAESEGAATTSKREEGIRSANQVFFRRRSRNLLPKCMHHQKSLALSALRRTTPFPLASRQNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3B3</accession>
    <name>A0ABR1X3B3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672809.1">
        <property type="nucleotide sequence ID" value="XM_066809191.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042251"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="49287" checksum="25896A3D06219DE2" modified="2025-10-08" version="1">MTKKPARSLPESGLSKTEEDSGARISEASSSTKRAGTDGSNAKDSSASHSDGGAKVEVPDGEPSTGNGLSREHSGSSDGARDSEAASDNASLTSDDATPVASGSVAGLDWAQPDHEDHFDDADSALGDDSASSTQSLSSSILQYRIIHGRRYHSLRGDGDTEYWQPNDEQQNLYAEYSTVSSELQAQCSYGPADITQTCCYLTAGYTSPRYPKTSRTSLMLVRGLDNDFGDAHPHAQVRGVDLSPIQPAWIPPNVLFEIDDIAQEWTYQPNHFDFIYLRSLHGCIKDWDLFFREAYKCCKPGGWVETFHMDLRPQSDDGSVRPGMAILSMYDHLVAAGRRMGRPMDLLVHHTMVRSMEAAGFVDVRETNLKKPMTDSFGDRKMREIGGFQHAALTEGLEGLVLYPLGQVLGWPLIQIQLMLARVRTELSSQKVHPWLRVQIVYARKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3B7</accession>
    <name>A0ABR1X3B7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="9">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004877</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Lipid-anchor</topology>
            <topology evidence="1 9">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672810.1">
        <property type="nucleotide sequence ID" value="XM_066809192.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042252"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF5">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 9" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044968802" description="1,3-beta-glucanosyltransferase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="328"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="389"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="48012" checksum="34DED11B006F5729" modified="2025-10-08" version="1">MRSYELLSTLAAAGLVVAGPTPTEPELPKRADSLPAVSASGNAFWAGKERFYIRGIDYQPGGSSGEADPLANTETCKRDIANFKDLGVNTIRVYMVDNSKDHDECMKMLADAGIYLVLDVNNPKYSINRNEPNPSYNAAYLQSVFATIDAFHKYDNTLAFFSGNEVINDKVESTKSAPFVKATTRDMKQYIGSRGYRKIPVGYSAADVSKNRMQTANYFNCGSDDARSDFFAFNDYSWCSPSTFQTSGWDSKVKAFKDYGLPIFLSEWGCITNGRNFEEMSALMDKEMTGVYSGGLLYEYTKEGNGYGIVDPKSKNVDSPDFKSFKDALKKYPTPTGDGGAASSTHSSKCPPKDDDWLVENDSLPAIPDDAKKYMKDGAGSGPGLKGEGSQNAGSTSTGTAAPGSGSVEATSSGKSEGGRPAPPMDMTMLAVSGVAGLFVLAGTLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3K9</accession>
    <name>A0ABR1X3K9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004905</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672838.1">
        <property type="nucleotide sequence ID" value="XM_066809220.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042280"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046262572" description="GH16 domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="19"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="497"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="814" mass="83358" checksum="E0EF404922F4FB1F" modified="2025-10-08" version="1">MAPSLINTVGVVAAAFVASSSATKSYKIADKYSSSNFYNKWNFVTIDPNNGYAEYQTQQGANDHNLVQLSDDGFYLGVDYNQAMPDTWDKYPGRRSVRVESQQTYNHGLFIGDFSHLPKPTCGTWPAFWMFGSKGEFDFLENWNDLTFNRITAHANNGLCTIKQSDMSASVVTNNCADIAPPQYDYQACSANSYDGVFGSDTGGVYATEWTSEYIRLWSWKVAPADVQAGKPDPSTWGKPMFQVSDCNIDQNFADLKFVLNINFCSVANQPDKWGATDGCATKTGKGTCMEYVASNGAAFQDSFFKVKGISVYELTEDPQTSTTSSTTTPSSTPSSTTSSTPVSSDLPSATATTSASASAAASASDASASVSDSAPASASVSTSDAASASVSATVSASTPDSASASSSGSAVSSDSASASSSGSTSASVSDPASVTGVTASDSSATTVPTASVTTPADNDQQSLSTSAFPTLSVSAPYKNGTISSSQLSLTPTVDPSSATQSSGAQSSGAQSSDAQFTTSTEFATRVYTVTSCAPTVTNCPVGSVTTETVALYTTVCPVSDKNNSPKPTPPTFLTQTAYVTNIYTITSCPPTVTNCPVGSVTTEVDTTTKLIPVATPTAQADSPVYSTVTRKVTNVYTITSCAPTVTNCPVGSLTTQVGTHTTVVPVVNSPGANGSPNGSPNTKTDVYPVVGPSGPNVNGGSDNGKTTTIVSTAHRTKTITIKPASSVAVYVTATVVPVGPSAPAIALVNALVNSTTNGTANASLSKPVMVPAGTPAAGCTGSDCKVPASSGNVRNSVASAAFVVVAGLFALAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3N8</accession>
    <name>A0ABR1X3N8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">beta-ketoacyl-[acyl-carrier-protein] synthase I</fullName>
            <ecNumber evidence="2">2.3.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004977</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.41" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672910.1">
        <property type="nucleotide sequence ID" value="XM_066809292.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042352"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF336">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="9">
        <location>
            <begin position="17"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8090016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="424" mass="45144" checksum="D821DABCF1C8FD09" modified="2025-10-08" version="1" fragment="single">NTKSFRLFKYGKNGNAMRRVVVTGLGAVTPLGVGVKRTWKRLLESHCGIVSVADYEPQKQWQELSSTVAGIVPKGSIDDGKWQSSDWLTQSEERRTSLFTQYAMTAASEALKDAEWSPSRREQLEMTGVCLGSGIGNLDEIYKTALAYEKGGYKKVSPIFVPKILINMAAGHIAMKYGFQGPNHTATTACTTGAHSIGDASRFIACGDADVMVAGGAEACIHPLTFAGFGRSRRVRGVRRRGRRRSRRAGARKARGARVYAELRGYGSSGDAHHMTAPREDGSGALLAMKKALKSAGLRPNQVDYVNAHATGTTIGDAAEAMAIQTLMAGPEGYTNDSEVTVSGTKGSLGHLLGAAGAIEALVSVLSVQNNVVPPTLNLHEPDVAPKFNLVPNHAQQKDVEVAITNSFGFGGTNASLVLAKYHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X410</accession>
    <name>A0ABR1X410_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylthioribulose-1-phosphate dehydratase</fullName>
            <shortName evidence="7">MTRu-1-P dehydratase</shortName>
            <ecNumber evidence="7">4.2.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MDE1</name>
        <name evidence="9" type="ORF">PG997_005053</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15549"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="4.2.1.109"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aldolase class II family. MtnB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.109" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672986.1">
        <property type="nucleotide sequence ID" value="XM_066809368.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042428"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03116">
        <property type="entry name" value="Salvage_MtnB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017714">
        <property type="entry name" value="MethylthioRu-1-P_deHdtase_MtnB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027514">
        <property type="entry name" value="Salvage_MtnB_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03328">
        <property type="entry name" value="salvage_mtnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640:SF7">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="8">
        <location>
            <begin position="47"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8090092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="276" mass="30946" checksum="9BFB71A7BA194F17" modified="2025-10-08" version="1">MSKRPEGALDSQMPDADQKRRRLEISENGDNAHLVHPEPHDHDHPANLIPSLCAKFWTLGWVTGTGGGCSIRDDDLVWVAPSGVQKELMKSSDLFVLSVAQQTDPKNRVYLHKPPAGRPSQCTPPFMAAFTKRGAGCCIHTHSHWAVLVTLILESQGPEKDKVFEINNIEQVKGFGRGHTKQGNLDYHDTLRIPVIENTSHEEDLTEFLEEAMEKYPDTYAVLVRRHGVYVWGDNVHKAKTMCESLDYLFQLAVEMKQLGLPWISNVSKVVTSSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4K0</accession>
    <name>A0ABR1X4K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005287</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673220.1">
        <property type="nucleotide sequence ID" value="XM_066809602.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042662"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF1">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="2">
        <location>
            <begin position="126"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="281" mass="31404" checksum="BA268C78AA08B5A8" modified="2025-10-08" version="1">MLLSRRLPRLVASTLHLLPLFRQQQYAAVAFTALNAAATNPLTCPATATPTSTISGPAKSHQRQQACAMSSSSAAAANGATEQSPTLAGTAPEETCAATTTKTEEKEEQKLPPLSAAEFRVYNRMAEHMDMFHAHFRQSWNLLWSAATSGKRPAGMSMRSFIMEGLQFLQYLTVHHDIEETHIFPVLAKKMPEFKMGTGKGKGAAELLRQHKEIHKGMELLEAYLMQCRSGEADLEMRVLKTKMEGWADVLWTHLDQEVKTLGAENMRKYWSPEEMRRLPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4T9</accession>
    <name>A0ABR1X4T9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005364</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673297.1">
        <property type="nucleotide sequence ID" value="XM_066809679.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042739"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="9"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8090403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="331" mass="35884" checksum="493FC4DD5DA84583" modified="2025-10-08" version="1">MPSFTVFKGAKDGKPVKSTTTRPDQLKGDQVYMRITASGLCGTDLHYKTVDMGLGHEGVGVVEDVGPDVKDLKKGDRVGWGYEHDCCSRCQECLKGNECYCPERQMYGYADLDQGSFGSHAVWREAFLFKIPDGLTDEAAAPLMCGGATVWNALRAYNAQPTETVGVMGVGGLGHLAIQFAAKMGCRVVVLSGSDSKKDEALRLGAHEFHATKGQTELKTSAKLNRLLVTTSAMPNWDLVLPNLAPGAVIHPLAVDEGNIEFPYMPLLLGGHAIQGSVIAPRHLHNQMLAFAALHRIAPVVETFPMSEEGIREAIERLEKGNVHFRAVLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7X3</accession>
    <name>A0ABR1X7X3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673480.1">
        <property type="nucleotide sequence ID" value="XM_066806184.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039244"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="88" mass="10099" checksum="46DD442A26B99BCE" modified="2025-10-08" version="1">MHRVVRHFGPRLRGLWFMERLVWREVERALLRIPWRNRDKHGGGGGRDGGEASALEGIDPWDILVGEDREVSRDLVASGQVRMSDLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7X4</accession>
    <name>A0ABR1X7X4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673527.1">
        <property type="nucleotide sequence ID" value="XM_066806231.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039291"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045715467" evidence="1">
        <location>
            <begin position="16"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="71" mass="7337" checksum="AD817C790DD92383" modified="2025-10-08" version="1">MMLIALIVFAAVAMGAVLPQAGQDARVANGQKSGSLIPRNILNTTCYGADLAGTREHGARDDAVLDAIQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X837</accession>
    <name>A0ABR1X837_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001976</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673587.1">
        <property type="nucleotide sequence ID" value="XM_066806291.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039351"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="315"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="59518" checksum="4FCE4B00C07746A2" modified="2025-10-08" version="1">MTQSLSGDIFWHATKSFIHHPVDVFNFARTCRSLWGLLEPEIYKTDVLFEPKKAETVGDDSHPFLYYLDTMLEEWEEPLLPATGHFPDEHEAYLSKLDGQNSGIDKATKNVVEGEEQFPRWKSLNILQWACSAGKVATAAKMIDMAERIWPEYCEYAHYESLHSPIHFASWYGHTEILRLFDRGDDQAMRERSGFICSPQRGLDEVLRHINPALGGDVPYGYGIQHTGRPFGLNALGIAILRGHEDAAEYLTQFHDEETIDKIQIDWLYDWKLTIPYIDPVIHPLHLACYMGMEREVKALFEQGADVLAPCVPVQNSNALQWAVAGRDNDAIIQLLLNKGALVNQRDVQNRRALEWALQFQAMANALRIANEEAYINIWLWSGRTCCALSLSMQDDANWDCTQLIFKETRDDLPDSFLRKCVHDTFANGKHSLKTLKWCIDQNIGLGPLREEDVGVDDWDVKDPVRGQNVGMAAIHYAAEASQVFTADILASILEKRPQDINLPNRYDETPLSLALGPGRYASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8Y9</accession>
    <name>A0ABR1X8Y9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673916.1">
        <property type="nucleotide sequence ID" value="XM_066806620.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039680"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045201103" description="Carboxylesterase type B domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="2">
        <location>
            <begin position="30"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="540" mass="57731" checksum="85E67258E5CA8D7F" modified="2025-10-08" version="1">MLFKLLPLAASLSFAAASPCAKPPSASGTPRVLLPQGTVDGFRDSHNNSVFLGVPFAQSTGGQNRWKRPQDLPLPQGNKSVAVFNATSYGLTCPQAITGTSYSRQDEDCLNLNVWAPSEGRGPAQVFVYMYGGAMVTGSSSNPQFQGNNFARNGVIFVSFNTRESIWASPNSAELGGDGESQNFGILDVEKALDWIHQNIAAFGGDPDHIVFGGHSSGSVHVDHYLWNHPDTWLKGAVQMSANAISGPAYAPSNAALDVVAAEAGCGTGPGQLECLRTVDALAMQTAFFNATANTWFTPVIDEITRFSDYPARFAAGAYPSHVPLLTGNSNGEGTIFSLVYSAENANFSEWITTFDADSAHIPASVLRSAYDYDHDVADDSATESRMSGTQYGDARFNCPVDFFVDLRSETQATWEYRFFGAYDNVVGVPGTAPTHGTEIPFFLGGNECFASLQGVTAAQQALADAIHAWFVAWIKNPAAGPGWEQVKPGNGSLAKLGVPGDELSRILGSTSEHSSRCQAVYKPFFPDYPVIQNPVRKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X987</accession>
    <name>A0ABR1X987_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002334</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the misato family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673945.1">
        <property type="nucleotide sequence ID" value="XM_066806649.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039709"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06060">
        <property type="entry name" value="misato"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049942">
        <property type="entry name" value="DML1/Misato"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029209">
        <property type="entry name" value="DML1/Misato_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019605">
        <property type="entry name" value="Misato_II_tubulin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391:SF0">
        <property type="entry name" value="PROTEIN MISATO HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10644">
        <property type="entry name" value="Misat_Tub_SegII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14881">
        <property type="entry name" value="Tubulin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Misato Segment II tubulin-like" evidence="6">
        <location>
            <begin position="2"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="DML1/Misato tubulin" evidence="7">
        <location>
            <begin position="119"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="425"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="544" mass="60779" checksum="99E45FC31BC5A299" modified="2025-10-08" version="1">MHEIITLQLGQQSNYLATHFWNTQESYFTFGDDAGESPVNHDVHFRPGLGADGTETFMPRTVIYDLKGGFGSMRKINALYEDQEAETPAVLWNGKTVVQKQQPIDMSAYQESLDTGAAAPELTTQNVRYWSDFSRVFYHPRSIVQLNEYELGSTLMPFEKWSMGEELFASLDKDHDLMDRDLRPFIEEADQMQGVQIMSGIDDAWGGFAAKYVERMRDEYGKTPIWVWGLQEPNAGIPREKRLLRLTNKARSIAELSSQVSLLIPLSVPSRSLASSVSLDKSSAWNVTALFNAALESTSLYTRLKSNDRANSLTMGSVTDMLNVFGKQTIANLQMSPVEQQAPAGGEGTGMQILSGRGELISRLNEMSYEDEEDTAGGQNRVESLDVDLSSLDENLGSAAIAAARGVGRRKAHLFSQFETARGDDAIKAASREEDDDPNDDRYGRVQRRQKSHRYQSSLAYPMLDSYPRIFRDKEGAVRRDPISMRTTLSTDSSVMTRLRGLRTTVVRSIGLEDREDIGNELAEVAEAYKEGWSSGSDDDDDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAQ0</accession>
    <name>A0ABR1XAQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000367</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674455.1">
        <property type="nucleotide sequence ID" value="XM_066804682.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037742"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20513">
        <property type="entry name" value="CYCLIN_CCNC_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028758">
        <property type="entry name" value="Cyclin, C/H/G types"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0195">Cyclin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="55"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="327" mass="36615" checksum="F9BF241414C649D7" modified="2025-10-08" version="1">MAASFWESTQRRYWMFSKEELAQMREKLCDEDPKLVQSYPFPTGNICTSTSINYLEIARLGKRLSVRQQVIATAQLYIKRFYCKVEIRRTNPYLVITTALYLACKMEESPQHIRLVATEARSSGQISSVLIRPGWGECEFFLISEMNSQLIIHQPYRTLATLQSDFYLTQDEINLSWSIINDHYVTDLPLLYPPHIVALTAILLSLVLRPNSMTGASAANNIAAAGAALAQAQVGRGGMGGSGTGVSSGQTTPGAPSTTDKDKQQEVRFGKVQRFAAFVAESQVDIEAMVDCTQEMISFYEVHEQYNDKATRDQINRFIKARGLDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB69</accession>
    <name>A0ABR1XB69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000593</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTH2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674681.1">
        <property type="nucleotide sequence ID" value="XM_066804908.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037968"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02430">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003314">
        <property type="entry name" value="PRK04322.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649:SF11">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="250" mass="26413" checksum="335281881F409E58" modified="2025-10-08" version="1">MSTHNTGTQSGPVGIILTTSIVAFISGFALGVFTIRGYLVSPSLSAERRANYEDPIESEESDIDDDTLLDHAPNWGNSLDADRRQGLRVTSAGTKKKAKKAAAKEEEKLVDVSEGSGPAAAADMHKTNEECKLVLVVRTDLGMTKGKIAAQASHATLACFKSLSRFPAGSPQAQLLKKWERAGQAKIAVQVKSQQELMDLKARARSLGLTAEVIADAGRTQIEAGSFTVLGVGPGPKSVIDQVTGGLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBF6</accession>
    <name>A0ABR1XBF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674748.1">
        <property type="nucleotide sequence ID" value="XM_066804975.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038035"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01111">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045083200" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanovirin-N" evidence="2">
        <location>
            <begin position="25"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="169" mass="17922" checksum="CFBA5FC3A40FEE9B" modified="2025-10-08" version="1">MARSTLSLLAFALLACLFASADPTPFNISCQQWSFNGNELTALCDMAIGSIATSLDLNDCYANYQGTLTPASMGQFTDSCTNRQLANYLDGSQPKPQPILSADCSEGAGKPTQHNEVNLADLIQNNNGLLQCLGNQGCYTCWADCIQCKDTGGLQPPGYQSGCDCGSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBY7</accession>
    <name>A0ABR1XBY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674983.1">
        <property type="nucleotide sequence ID" value="XM_066805210.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038270"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="119" mass="13064" checksum="B14629C8CF4675FF" modified="2025-10-08" version="1">MKDRCTIFYPIKEPTGLALETPRGLVSNLRVLLTVAPVLILQLVLGLPAMQGQDMMAIHVARDRATAPLTATMTAPRSIATEGRGGLQRKPVSTMHPSRPTEMDSATRFRGTRREGLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC27</accession>
    <name>A0ABR1XC27_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674950.1">
        <property type="nucleotide sequence ID" value="XM_066805177.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038237"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021487">
        <property type="entry name" value="DUF3140"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40630:SF1">
        <property type="entry name" value="DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40630">
        <property type="entry name" value="POSSIBLE DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11338">
        <property type="entry name" value="DUF3140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="135" mass="14756" checksum="67B6D2A3EF655426" modified="2025-10-08" version="1">MTASDLEGWLKGESSESAGWAKDDGSGETVGHESGRKIIEILKKNPEKDAAKYDEDDLPHTRKVVAYCKRHLAQEGKAKQDTDSKSARSLKNWGARSAEGGLICSFILPGGYWLGRMDSQCPDRQSVPASGHSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCD6</accession>
    <name>A0ABR1XCD6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675055.1">
        <property type="nucleotide sequence ID" value="XM_066805282.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038342"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="115" mass="12651" checksum="04110DE725B2757D" modified="2025-10-08" version="1">MPLSSGAAGAGGPDATRLLLEYGAHPNETDKSPRSCLQHAAIAGDADSVKMLLDAGASIEASRYINKRTVPRLNETWRKKYRDALTEAKRRNYVAVVRVIEEKQREIAETKAVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD30</accession>
    <name>A0ABR1XD30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S5 DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675333.1">
        <property type="nucleotide sequence ID" value="XM_066805560.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038620"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="6">
        <location>
            <begin position="269"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="433" mass="48101" checksum="76326F72A09938F1" modified="2025-10-08" version="1">MSVARPARCLLSKRFAAALKPATPTCNAAFHSSAHLEARKKQRFKSIRAGEMGLTSPEKVQKYTEENFQPYTPEEIEVLKKHYSSEQMEALQAGEAAIDPKDLTIQGRLRRDPYQIPYLDDFSRLAPIRWLTEDEFVNDIAKFAKEVDAPQAKIWMEQKLNDPTLSEEQKDWVKGQLAKVTAQADRAKSLDGKGGDAEGLDLMFERSMLNDDNAPSDTSVAPSLGKDIPGISGIYQNPIDPEDQGLDDEGIYQDLKRRTGLSVREMMDLTVKILVVRLVHNQTRLGKIRSVWVLAIAGNGNGRLGIGEAKSVENGAAVQKAKLLAIRNMKPVPRYEERTIYGSVSAKFGGTIVKLDARPPGFGLRASARFFEMFRACGIHDIAAKMPRSRRPMNAVKACFEALTNQKDPNEIAIGRGKKLVDVRKVYFGGNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD36</accession>
    <name>A0ABR1XD36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675384.1">
        <property type="nucleotide sequence ID" value="XM_066805611.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038671"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263:SF0">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045482380" evidence="1">
        <location>
            <begin position="20"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="477" mass="54180" checksum="33F42F26F1CA2A47" modified="2025-10-08" version="1">MAPLALWSIVPLFAALAQSSWVPPMPMLPRNTEPRWQKEIAPRLTNTTDQWPYGPFRTQGRDIVNNRGAVLSWAGINWPMSGETMVPEGLEWKSVDEILDDVQSVGWNVLRMGYATQMIDEIYERDGNDVSLEVAMIIGLGYENGTKVTNQIVSKNPGWTAQTTRFEIWSDIADKALEKGIFIHPDVHVHQAKWCCSHTDGNAWFDDVHFNTSNWRRGLAYVADWAKRHPNVVSMSLRNELRSSWNRTDLYYNWQTLVGNMSAGSDAIHEANPDLLISWSGMQYDEDLSALTARKNILTAPCYKCDAIRDAHRRDPVYFDLDSYPWADKVFWELHIYPMSEDVDTGTCEAVEAALYRAGFHALGMEPPPGCGQNLTGGDCPPPQRLTPVMLTEFGHAQDATLYDDTLQNCLVEYTKKHRVGWMVWSLAGSYRTREGVQGLGDTWGLTNFEWDGWNDAETVENYWKPWVKAMNATTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDW5</accession>
    <name>A0ABR1XDW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase family 90 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675627.1">
        <property type="nucleotide sequence ID" value="XM_066805854.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038914"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="59253" checksum="140F0795A0004A90" modified="2025-10-08" version="1">MVLIAGLPRLGRFCGLGVPRRSSSRVYIFFALVACALLLSLSWDASPFPSVTWGLLEPCAGREHADCFHALYPRRLPAISRHQSSEDVDEDDDDDTVKPVFSPRLKQVIAPDGAASNHFNKRLFHSLWRRFWIQVSRCLDRTGLTWRWRYSRDAHDRTLSRHQCRKAFPGLFDELLRSKQQYEKYHTNLDDLEDIEIQDGRVRVAVLDGRVGQPICSWVKGIQVLTSSIDLKLRVTKSNLLAEKSRVAAVATLQSIQQSIIDAPKQDIPNIEFVFDVRGQVADVTKPVWVLDRREQDDKVWLTPFIGSLEASNTSSSGRQMKRDGSQAKYTFKSLAQIASEIDSQGSQGSSGRNGKRDETKDAGDSDDWGAFLLTSSPPRPDMTAPDVCRHKIFLHPDSQSTFNRLDSLLCASVNVVKRPQWIHLYHGLMYSKPMTGSRSSLPDFQNVMLVDKSGPDLEKGTPGFLRNTEVARAMASNAVETFRHRYLTEASTACYWRELIHTYSEVTFSPEVYDETGSRRESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE16</accession>
    <name>A0ABR1XE16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001544</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675632.1">
        <property type="nucleotide sequence ID" value="XM_066805859.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038919"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="220" mass="24784" checksum="2165EBAC13DB8D67" modified="2025-10-08" version="1">MRLPVAASASRALALFGTQKQFSRVKTLTTTTSIPGGTPFKFCPESRSTDLFRISSVTIEQQPIYMSALMRHVTNSDDVFKIHIEGEFQNTFSPNATMDVTENCGSYCETYGTDPADRQGETYRDDFCGLNPLEQPLGGRTDNTACPSEKGYAMISPVGLAMSMFLWWPAVYNFTFDAKTEDGRRIYCLTAEVCMRWEDEEKNERYSTGPWSNCTWPSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE28</accession>
    <name>A0ABR1XE28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675729.1">
        <property type="nucleotide sequence ID" value="XM_066805956.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039016"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="74"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1029" mass="116539" checksum="5DF2FE9B942F1980" modified="2025-10-08" version="1">MAFKDACFTDEFLPITSSNRHMITSLGHDNRDVSAPWSSAHAERFMEKQWEFLVRGISKSDLDWDLDPEHILPFRVVRDFSHGDSQGGSRLSGSPATVLKEYYPDAISPLRFQIGEEEEEKRDEDENAEESDVQEEEAQEKETQPVVAVKEYRRDVPRGKEVQALKKAKEMGARHCIELLAVITRGDMCYLVFPWADGGNLSEFWSSHPKPRMTAGLMRRVVRQLKGLTDALNTLHTSTDGSSCFHHGDLRAETILRFRTRPKTDREIDVGVMKIANFDLAQVENDSPEVRLTAVTGDPLLDIWSFGCVVIEFMIWILYGRTELDQFRYLRLNTLWENRSSARGGSSKTLVQPVLNRAMETILADQECQSQSAMRDLLRLVKNSLLAARLEEPHDVLHSIRSSSEIRPRKSDDEVPYGDNEVLSSRGHANTFRKALGTIQKRGRVAHYYWYTNLQRYDIQKRMFPLEGMTSNVKDMQSTENTVEIKGTKVNDQWFFPVDNDFVVESGLLYSEEAQFGSRTPPGETKRIPKDFQIGMPALADAGSSSHFAIIQSWLDSCTKSHADCATPIVRQRSGICVPSRLLDIGSDGDPTIKLLDISSTTWLRYIALSHPWGPGPHFCTLPSNLNGHKQGIADAVIVTRRLGISYLWIDSICIVQGPEGDFDTEADRMEYYFGNAWCVIVASSATSQTDGFLRPRTQQRDFVTVESHYKGRPRFHVCEFIDDFQKDVRGWVFQERALARRSIFFSEGQTYWECGHGVRCETMTKTSNLLASYMGDPNFPSRLADGVTRLETIRGYESLYSRYSRLALSRATDRPVAIRGLQRRLIRSLGVPGPFGVFDDRRSYLQHTLLWRRGRDVASLARVPGLVGRVPSWSWMAYGGGIDYLDLPRGGGVLWKAGQVEAPWRSDELDSRIALDVGTAPRDMELKAVARPFGLGFLGDSEPRRRPEIIYDDPGAGIRDPSRLRCVAMGREDVRGKAEADITHYVLVVQLTEGRLNMNDVYERVGAGYVDGCLIDWRESEMSWVTIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE51</accession>
    <name>A0ABR1XE51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001549</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675637.1">
        <property type="nucleotide sequence ID" value="XM_066805864.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038924"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47783:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47783">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="138"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="290"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="474"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="716"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="886"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="951"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="951"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="999"/>
            <end position="1011"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1100" mass="121531" checksum="61FE2059F3775F4A" modified="2025-10-08" version="1">MTPRLPRTRTGVLEECATHPASVLEDVEAHPSRPHPSDAQEKGPAYFRGTNTPLTTIRGGGHQQLTTATYLKPLILLHYTKSSELLELYADDRPVSYQSCLTCRKRKTRCDGEHPTCHTCSKNGHVCLGYTDAAEKKKDPLNDQDLDVASDNDDDLDERREDKRQQWRPKKPAVRQHSSTASLDSSRRFSESSRSTALAPSTVRPKQESIDWEERQNSSKNGSTPMTRRPPNVRNSSFSTEDGRSPSIRSPVLQHHSSEGYRVPYFRYFGPTAIVPGFKQMVVKVRNRRRSSITATSPSSGATYTGFLNSGQSDHSAAHPDDMPVYDPNDADPVDPLILNLVDTFFDHQGCNYPFLRRDDFTRSVKLKQVEPILVDAVCALAARFSVSPVFGNGPKAENGQVFAQRAKAATVDTFPCPSVAAVQACLLMAYEGFGADQDSALWMYLGLAIRMAIDLGLHKKDGVRFQGEKDPWYARSANRKPSDEDDTKMSDSEDTLSPQEQKKLEQERIDTLWSVFILDRVISSGTGRPVTLRDDDFELEFPKPAKNKNNDWPDPFPSLIQIIHLYGRVSDVLNKLRGTKDLTPERMNSLLQMEKELTRLHLKQDPRLRFDATNFQSHVRNGQGTPFILLHFWFHALIIVLHQPTLLTPLESLNQDHPLLPHSRELSMSSAKTIVDILAFAKLLSEKSFIGNPFTSQPIYIAACAFLKESVAHPSSQPASRDASPLRDQQGMMGRATGGKNGNGPEHKSSDRHFLLASVANQNYQSCYEALQQMQIYWGGVRYILTALDQKFAGTWDCETYTREEYESTKQPRRNDLHRFLIKDENYPASPTNNPAAQHMDMAPMPAAQPAPPASAPTPPGNMIYDPIRQSLPETTVQMYPPAYPQPNTSAIRHSINPHRGRRVSTSSGPTKSLLRYDNLSEDSVKTPTTPDGKFSLALASQGSSVTLTSASFTPTSQHSSGFDQTIYPPGASPSSTLTELHPSSAHGGQQPYIRGASGTNSTGTPTNSSVVFNPADNGSTGGANGPSGFAQSGSGLASSGYSYLGPNGQEMHLVTIDNESDFTQHLSSFESSDMMSWFGEYLPNDVGLFTDMTGNGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUA9</accession>
    <name>A0ABR1UUA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014612</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661114.1">
        <property type="nucleotide sequence ID" value="XM_066818926.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051986"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF12">
        <property type="entry name" value="STERIGMATOCYSTIN 8-O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="280"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="458" mass="51230" checksum="EC8DA09F37FE38D8" modified="2025-10-08" version="1">MTDSRSLTELGRIIQSRSTTIAAWLGAAEIPQPSLSATYPWQEIDYPRDIEQDRAEILEALDELRTLLLGPTSYLFHTSITSVSYRALGRRLRMTHGHHELTDRVQPVWVAVFTTLYRFQIAQNVPRQGSISYTDLAAQCDLGELDLRRVIRAAVSIRIFEEGDGHVRHNAISAALASPLSHDAVGFFAEEFHPAAMKFSEALRQFPGSKMAGESALALVNGLSGDMDIFSHVSKDPVRFERFANAMSWMAMMPGTASSHFVNNVPWGRGEGQAVPACPRTIVDIGGSHGDLCKALLRGYPGIERAIVQDLPRVTQISLEETFEAEYSNRIEYQAYDFFTEQPVKEADVYIFRTVLHDWPDSYAIKILRNQVPAMKPGARILINDICLESGQHTDPLTQQAQCTHDMMVKMGVNAQERTTQEWANLLSEANRGYKINSIVSPQSSVHSIIEVVWEENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUF1</accession>
    <name>A0ABR1UUF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660916.1">
        <property type="nucleotide sequence ID" value="XM_066818728.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051788"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045702">
        <property type="entry name" value="DUF6060"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19535">
        <property type="entry name" value="DUF6060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046855071" evidence="1">
        <location>
            <begin position="20"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="300" mass="30994" checksum="9248E1ABCDE9B58F" modified="2025-10-08" version="1">MHRYSLTALLLAHAGLGLGQDVTWCKDDKCSDCPSGLASSGPGWPECVVYDSNVVFGGQGFDEDVAGKLRYRVYGDFKEPCGGASGNFMIRSPASISAVGCGNLVYSTQKAQCSGSITLEDTFMVQFCCGAGDCDAAHVPAGKRGDDLMLSGGGSSGGGVYLQFPNGTMIEPLAVGTPPPPTSFATRRAAAAAAIEARACEGYKEGSASTSTTFEASVGDALGIISVSVGFTFENSTSDAQSIAIAVPAGQSGYIGWTPIYRCTKGSLETCDDVRTGSKESCTPYVSDGVIRGDYLFVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUT1</accession>
    <name>A0ABR1UUT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_014783</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661285.1">
        <property type="nucleotide sequence ID" value="XM_066819097.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052157"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF54">
        <property type="entry name" value="FAMILY OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="3">
        <location>
            <begin position="85"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="373"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="47525" checksum="C79111648E7076F5" modified="2025-10-08" version="1">MAAQTSLPSIVDYNQGHLEDNAHNSSHPPSIPSNFPSQIQGPTAWSGLDDDEPTHIFELTEQDVADVEIALERFKGLGMHGDQISRELFPLPSLESRLDRCALEVHNGTGICVIRGLESKYSIEDYMTIYLGISCYIGNRRGLQDAKGSMLSHVTDSKTWTVPLERRHGIHTNYGLPHHCDMGSDILSLHVRKMAAVGGRLCVASSHTIYNELANSDPSALRTLIEPNWPIQASLRRKPPYTLSPLFEYYRGNLLFSADPARLGPLASAPRTAAAAKAARRHEICLESEPGDMIYLNSWSTLHARQPYQDGETFSRHLVRMWLRNDALGWPVPDSMRMPWDSSFGDAAAKILNRRYPLVPMPIYMEPRYHNNTAAFVPDDDDDDSSDDEDDGSKTTGGESSSAGPSTTTTTAATAMDEDSSTEPAVADDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUV9</accession>
    <name>A0ABR1UUV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661297.1">
        <property type="nucleotide sequence ID" value="XM_066819109.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052169"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="194" mass="20963" checksum="F4337E541C6F94F0" modified="2025-10-08" version="1">MPPTSTHPQPATPVPVFLRRIALVQYAFCWILLLAHGIAARTALPALGLLPLTSSALLSGLLLHRDALAAAGSPVQTSLSAQNVMYCDLVVAGVQLTLLIFSWIDMSNHWGHNSLTILGTYGTVFMMVDCGIHFYFALKEVFHILLSPKCDCPHCRSVHGRGRAGISLPEDDEYTPLQSDVGDDSAPQDASEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUY0</accession>
    <name>A0ABR1UUY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ysc84 actin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014836</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661338.1">
        <property type="nucleotide sequence ID" value="XM_066819150.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052210"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11524">
        <property type="entry name" value="SYLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF8">
        <property type="entry name" value="DUF500 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="2">
        <location>
            <begin position="96"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="227" mass="24035" checksum="55666FCFA70496E2" modified="2025-10-08" version="1">MDKEIAKAQKILKSFTKDGVDLGSTTPSPNSDASKKSKSRAKIPAEVIQQAKGIAIFTTVRAGMWVSGSAGSGVVMARLPDGSNSWSPPSAFSAYTVGAGVILGADHTESVCVLNTDEAVRAFAQERFGFGAGLSVTAGPVGAGTASLHGARDPVWIYSKSRGIFLGAQVDGTRFNARDDINEGFYGEEGITPERILRGRSRRSWRGRHKGFLGALDKTRLCIGRLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVH1</accession>
    <name>A0ABR1UVH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclin H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_015009</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661511.1">
        <property type="nucleotide sequence ID" value="XM_066819323.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052383"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20524">
        <property type="entry name" value="CYCLIN_CCNH_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20525">
        <property type="entry name" value="CYCLIN_CCNH_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031658">
        <property type="entry name" value="Cyclin_C_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16899">
        <property type="entry name" value="Cyclin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin C-terminal" evidence="3">
        <location>
            <begin position="150"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8062912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="314" mass="35552" checksum="C8AF57E0559F3BE7" modified="2025-10-08" version="1">MATEDARYRQSSQYRLWSFTTGHLASLRNECNSLAQKAISARLQSASPNDALPEFLTPAEELSLVTHYTVELLRAAAFIELPTEIRATAAIFLRRFYLLKTCLFFGCKAEGHYMRLSKFADKFPNTTGEEVLAAEYVLSQGIRFAFDVRHPFRALEGAIMELRRLGDFENKRIDRAHGKAREILKFSPLVTDAYFHYTPSQIMLAALAMADEGLVERMLREAFAAQGVPGHAREGAPEKMNDNEERKAIIKPLNRKLKKCRDPDRVDLVALQKARREQAMVKKPKIPVKEDGAVFGGSIADGRESKRRKTETEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWN6</accession>
    <name>A0ABR1UWN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660822.1">
        <property type="nucleotide sequence ID" value="XM_066818634.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051694"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="28529" checksum="4DE7E5909A232736" modified="2025-10-08" version="1">MQLITKLTTDDVKVSANDQGVAVLQMDRPAKRNAFSQAMIDTIVAALRELDRMPEVRAVVIAGLPEGPFCAGMDIKELVAITTAAAHRRAFLKDLTDAFAGFSKPTIAAVVGAALGGGCEISLACDMIYAAEDAMFGLPEMKIGTIPGAGGTQRLARALGKHKAMEFILTGEPASGAEFERLGMVTRVFPKEKVLEEAMKLATKIASLSGPVAQIAKQAVLTAESTTLEMGMTHEKALYYATFDVADCHEGQRAFLEKRKPNFEHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXM6</accession>
    <name>A0ABR1UXM6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661152.1">
        <property type="nucleotide sequence ID" value="XM_066818964.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052024"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038966">
        <property type="entry name" value="TMA17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422:SF1">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="226" mass="23735" checksum="E59C25282CBA2356" modified="2025-10-08" version="1">MSAQARPPTAAEFASALTELPASSLALKVLEMRNQIAHLDYSNSEMKPFAEGADGAEPDQICIDGIRENEEIIVKVQQRIELVRHEVERRGLSWPEFDGKDVATGAVAVAPSLEGQHDDDRANASLLSSLVAGPIPAAGASSSTTDDPAAIRVTTTTTDTNGATAATNGTNGHSSQNAGADRALLQEAMDAGIIQRMSAQEFVESVMASHENNPNGDTEDDGGMHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1Q0</accession>
    <name>A0ABR1V1Q0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661870.1">
        <property type="nucleotide sequence ID" value="XM_066816178.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049238"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="117" mass="12905" checksum="0CF2DB45148B04DB" modified="2025-10-08" version="1">MTGVYGSQARMTAHIIAAATARGSHIGVGTDKTVVEVSKEAEQAWLDKLLRYATWFAPLLTTCPPTYFTGYRSGEARDEKELAMVKRKLLYPLGPVGYDHAGQDYIQKGDLEGFIVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1Y3</accession>
    <name>A0ABR1V1Y3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein G</fullName>
            <shortName evidence="9">snRNP-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_011935</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661942.1">
        <property type="nucleotide sequence ID" value="XM_066816250.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049310"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01719">
        <property type="entry name" value="Sm_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034098">
        <property type="entry name" value="Sm_G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF2">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="23"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8065188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="102" mass="11317" checksum="F3F267AD665DA21E" modified="2025-10-08" version="1">MAPAQPELKKVSARENLAGELPQELTHLIQYLDKRLFVQLNGSRKVIGILRGYDVFLNIVLDNAVEEKDNGTKETLGMVVIRGNSVVMLEALERIGGGDRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2E5</accession>
    <name>A0ABR1V2E5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661861.1">
        <property type="nucleotide sequence ID" value="XM_066816169.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049229"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="109"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="715" mass="80823" checksum="8DCE46F5F05F9E53" modified="2025-10-08" version="1">MASGREDWETAKLGLKRDLKKFVNRKWSNFRTPPSSDPSTPAQEAEKQLEQDRKDQELLEWTQQLPAFQYRAIPDKGYIRLLEIVPAPDKEWIQVRVSNVSLEDSAQTYDALSYVWGDPNQPRRGISVNGCHFEVYESLYDILFSLRPGPDSAAAASKVVLWVDAICINQEDVAERNAQVPIMDSIYRNARRTVIWLGPETKKTQRIFEMLENLANDSKTAAPDPSFREQETLPLTLMQYHKAPRVKSSIVEQYGGEENIWRVLKATWWFRSWTLQEILLSTNITFFMGRYKVDWEDFCAAVDHGFRLRIWSTLEQGTFVNKDILPYFTIKDLQRRLGLYSSTDRSSEAEHGPEILLTLLEGCRQRESKDPRDKIYAVSGILKNIQRLSSPTDAVNQVKIDADYASPVVYVYRMMSQQLILTTKTLDVLGIFPAPPGGACPPGPPRRASPADAVTLVLRGHEVATVTEISRSIPRYDYTAVPFDADYDAREAKVRAEAAARGDEDPTEFAVSMMTMRDLKGEFKKIFTDEAQHWHVLIQWERFAARREPTNPLGTNNDGGSDGGNGPSSVYWKTLCAGTYADDDAGATEKLFAAWSRSLEVLRRNEKRFGSLGYGVHPLAYVLSSAWADAGFPEFALYCECAIERRLGWCGNGWLALLPEGRAGDRIVLAEGGRVPLVVRPDGDGYYTFVGEAYVHGIMDGEAFEQDRCRDIKIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2G6</accession>
    <name>A0ABR1V2G6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tyrosine protein phosphatase PTP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662136.1">
        <property type="nucleotide sequence ID" value="XM_066816444.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049504"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18533">
        <property type="entry name" value="PTP_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF449">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="188"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="355"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="480" mass="53836" checksum="05FCC4705A676055" modified="2025-10-08" version="1">MPDFSQRFRRSKKGAMGRATSPVSAPSSARNSADGRATTPAREAPPALTITTSTTPPRSSHGTQSATSFHPPKSPFRNFKFRSSSKRARSPAPASLAQPSNPAIVSHGPGGEHESKERTAGQSDVAKVSKQGNALHKIPAFLNLSVVDIMNKYSDINWTEGERTMLGTQDPLAHPQYAPLSPMYRNLDRYGNVQPWNSNRIKLQVPEGATDYINASPIVLESPLNPEERPPHRYIAMQGPKGNTTEHTWRMVAEQLQSPAVIVMLTETHEKNMEKCYPYYPREVDETKELGESDEFGDGFRASLKCVSMEEKAEGAIVMRQLVLHVEGRDEDMVVWHLLYKKWPDYGVPALEDIESFFELMRLSRAKNASPDNPRIVHCSAGVGRSGTFIALEHLMREVDSGDLENYDEKNGGADAPDLVFDTVNTLREQRRMMVQAEPQFLFIYQVLRKQWMEKYNVVVEDDEPASKRLEVAHDPFVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V397</accession>
    <name>A0ABR1V397_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012413</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662419.1">
        <property type="nucleotide sequence ID" value="XM_066816727.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049787"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024729">
        <property type="entry name" value="USP7_ICP0-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029346">
        <property type="entry name" value="USP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF644">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14533">
        <property type="entry name" value="USP7_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12436">
        <property type="entry name" value="USP7_ICP0_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00061">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="MATH" evidence="8">
        <location>
            <begin position="76"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="233"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8065666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1139" mass="131494" checksum="CC6CB268C27E09FF" modified="2025-10-08" version="1">MSYDPEIHSPNEMVVDSSDDYIVPAENEKEPVAIINPDSLDTDVDQPENVTLATDFETMKELVLPPLLEEPKILDDAVDTWTIESWRNLSKREHGPVFQAGGFPWRILLFPFGNNVDQASVYLEHGFEDPSKIPDDWSCCVQFGLVMWNINDPSLFTYHTAHHRFTKDESDWGFTRFLELRRMFQQPWENSGKPLCENEAANITAYVRVVEDETGVLWHNFNNYDSKKETGFVGLKNQGATCYLNSPSPAVYQIPTAEDESIMNSAYALQRLFYQLQTSNSAVGTNELTKSFGWDTRHIFEQQDVQELSRKLMERMEERMKGTAAEDALPKMLSGKVKTYVSCIDVDYESSRIEDFWDIQLNVRGISTLQDSFKDYIQQETLDGENKYWAGDDFKYQDAHKGVIFTSFPDVLHLHLKRFEYDIQRDAMMKVNDRFEFPDLFDAAPYLEKGADVSEPWVYKLHGVLVHSGDLNAGHYYAFLKPNKDGWFYKFDDDKVTKATMRETLEENYGGEYRASHNQLRSAVQKKTPIMRQMSAYMLVYIRESRLDQVLTPVSEDDSPLHLQKRLEEEAAAREAKRKEREEQHLYQMVKVVNEDTFKHHGSTDLTYFDGDAKVDAAAPRSYKINKKASMEEVLSIIGEDIKQDPRRIRLWLMVNRQNKTTRPDQPIMDLKPSVGETYQRTASSSRDNALRVWAEVAEETDDQGEAIWPTYQSNANGVVVKTTDLILLFIKCFDAEKQSLLGVGHVYASKEKKVEDLVPAICKKMGWGDKLPAGEQMAMWEEIKPSMIEPLKAKQTLKAAELQDGDILCFQRMPERRVPGDILGKTLRMNEKQSDDGVKKWDHFETAPEYYDFLNWKKEVKFWPHPTRCDKEYENFCLTLSSRITYDQLAERVAYELKVEPTHLRFFTINGSTGNPKTPVRRVLSQTLHQILNPQSNFAANSQTKPDALFFEVLEMSLAELDTKKNVKVTWLSEGVSKDDTFDVLVNKQGHVEDLIQAFSKKAQIKDEQDGGRIRVYEIHNHQFHRELSPSYPVLSINDYTEVIAERIPDEELEADERNFVKVIHFQNDPTRVHGIPFKLFEKIKFAAVKKYEKKATYLQDDDVLFNEGGALEDDLVLGLDHVDRARNRGNGQEMFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3R8</accession>
    <name>A0ABR1V3R8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase regulator Ste50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012564</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662570.1">
        <property type="nucleotide sequence ID" value="XM_066816878.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049938"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01786">
        <property type="entry name" value="RA_STE50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09533">
        <property type="entry name" value="SAM_Ste50-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051569">
        <property type="entry name" value="SHANK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24135:SF28">
        <property type="entry name" value="LD13733P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24135">
        <property type="entry name" value="SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="2">
        <location>
            <begin position="56"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="3">
        <location>
            <begin position="375"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="478" mass="52230" checksum="CF2FE4CB6074079C" modified="2025-10-08" version="1">MNFDSGTAYAESDADDEYERNLPTDSEGRSSTEHTPTTYGHRSSADRLPETIITEWTAEECADFVATIGLEQYSDRFLENEIVGEALVALLHDDLKSMGVASVGHRLTILKSVYDVKKAQDIPIESDHYVPQSAEAEAQYATATLKDIKHLVEQLRLRDERMSLVEQDLRRLTDDYRRLREDMLPALRLAKNAQQPLPNVSARENQGYSYESSTISPPAPTPSSIQSSGGNLKRQYSTKKIVLGTTPKNASPSYLQTTHERPSVEQTLDPASAAERAVLSSSHLAAMNGSGQATSPGYSPNIPSPTSPPTMGSATLGSRSYRSDQPTPSSRSTFAENDHIYNPGSASSKQPVAPRRMQTPAPDTPGSGSSSVEIFKSFRVSMDDPCYKVLPAALRKYQINAPWDQYALYIVYGDQERCLGLDEKPLILFKQLDKEGKKPMFMLRKTNTATVDADAPGSAGLGSTNARGVAYDPPGGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V471</accession>
    <name>A0ABR1V471_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012714</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662720.1">
        <property type="nucleotide sequence ID" value="XM_066817028.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050088"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF40">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="560"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="584"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="595" mass="65963" checksum="A3FE3BF7B61A23B8" modified="2025-10-08" version="1">MPLQPSASLPAAVSASSTRRPSNTTGVELPDRTSVSTGHTRFNAQLSRRRHNNQAVIVNPLSHLTDEELVADVHQFQAHYLGSVESDDLLRAARVAKDVRTYDEVARSEDPAAGSGLPVTLDPKEKEALKAEKDVLFSERGMFIVILTGSQHVPSGQEPPAPVWRLGAANASPFLFAAVVGCFVSLPINDLVGRRGAMAVAAVLIFGSSLGSAWCRTWGTLFGVRAINGIGMGIKAVSTPILASETAVGFWRGSSILAWQLCHEDKILSLILGSPCVPALFLLAGLWFCPESPRYYMRRKSSRFSPMKAYEMLKRIRTTECIRFKGEAAAYFVLQALRDIYLIHKSVQLEEYSLETDVESQEGPVRKGLLSYLRGYLSEYADLATRRRLRNALVSSSTVNLAQQLCGRANTDARSQYAGIQLWRKWLILTLPLMCLAMLGAALSAALIKEHDDLRVGIVTFFLYLFSAAYSPDWDGGALGLFSGLNLLAFALVFLLVEETKRRSLEDLDLVFAVRKGHFIKHQLTQYLPRWFQYYIRRDKTAEQPSLYLDLIWGPKAEQSPGIFDPSNSPPHHHDVGEQSIEPEDVRNSTDTDHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5J4</accession>
    <name>A0ABR1V5J4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662022.1">
        <property type="nucleotide sequence ID" value="XM_066816330.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049390"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046578339" evidence="2">
        <location>
            <begin position="29"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="99" mass="10656" checksum="B8BED64D2C3126FA" modified="2025-10-08" version="1">MPTQALPPYIQADCFLLLYLFPAAATSSSQPTTARKSKKKSKSHCLRAYLQQPESRLITKSNAGTTAVAAAASHAISQASSEAKMSRDIKKIMGPFERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5K0</accession>
    <name>A0ABR1V5K0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Heavy metal translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_012287</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662293.1">
        <property type="nucleotide sequence ID" value="XM_066816601.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049661"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00003">
        <property type="entry name" value="copper ion binding protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF8">
        <property type="entry name" value="P-TYPE CU(+) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00942">
        <property type="entry name" value="CUATPASEI"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0187">Copper transport</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="403"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="450"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="662"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1026"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1055"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="16">
        <location>
            <begin position="12"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="16">
        <location>
            <begin position="110"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="16">
        <location>
            <begin position="201"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="16">
        <location>
            <begin position="282"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8065540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1139" mass="121169" checksum="5BD3E6CC7ED06295" modified="2025-10-08" version="1">MAPANIKTASWATTTLRVGGMTCGACTSAVEAGFKGVDGVGNVSVSLVMERAVVMHDPERISAEAISEIIEDRGFEAEVLSSDLPSPAFKPFDKLFDADDDNDDDEPTTTVTTIAVEGMTCGACTSAVEGGFADVTGVKHFSISLLSERAVIEHDASLLPAEKIVEIIEDRGFGATLIDSEQQKQSRSLDSDGEVKRATSATTTIAIEGMTCGACTSAVEGGFSGIDGVLRFNISLLAERAVITHDPAKLPAEKIAEIIEDRGFGAAILSTVFDTGDHSGSSSTAQFKVYGSPDAAAAKGIEEALLALPGVNTARLSLATSRLTVTHKAAVTGLRQIVDAVEQLGFNALVADSDDNNAQLESLAKTREIQEWRRAFKVSLTFAIPVFFIGMIFPMMIPALDFGALQILPGLFLGDIICLVLTIPIQFGIGKRFYVSAWKSVKHGSPTMDVLVVLGTSSAFFFSVMAMCVSFMFPPHSRPSTIFDTSTMLITFITFGRFLENNAKGQTSKALSRLMSLAPSMATIYADPIAAEKAAEGWDDVQASGVPKTPVVDGNAAEEKVIPTELIQVGDVVVIRPGDKIPADGMIVRGETYVDESMVTGEAIPVNKKKGSHLIGGTVNSHGRVDFRVTRAGRDTQLSQIVKLVQDAQTTRAPIQRLADTLAGYFVPTILFLGLMTFIVWMVLSHVLKNPPRSSYKSRAEADFMVGTGVGAENGILVKGGAALETTTKITQVVLDKTGTITYGKMSVATAKLTSLWEGNDWRRRLWWTIVGLAEMGSEHPVGKAVLAAARTEIGVDMESAIDGSIGDFEAAVGRGISATVEPSTSGQRTRYKVLVGNVRFLRENKVEVSEDDIEASEEINSKANKSKASTSAGTTNIFIAIDGKYAGHLCLADTIKEGASAAIEVLHRMGIRTAIVTGDQRSTALAVASLVGIAEDDVYAGVSPDQKQEIVRQLQAQGQCVAMVGDGINDSPALATADVGIAMSSGTDVAMEAADVVLMRPNDLMDIPAALHLARTIFMRIKMNLLWACMYNIVGLPFAMGIFLPLGFHLHPMAAGAAMACSSVSVVVSSLLLRFWRRPAWMDEALLAEKGGIKRRGRGWGLDSILTRVQGVAGSVLGRGPKKDEGYVPLATLDRHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5L5</accession>
    <name>A0ABR1V5L5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Meiotic chromosome segregation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663242.1">
        <property type="nucleotide sequence ID" value="XM_066817550.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050610"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018959">
        <property type="entry name" value="DUF1989"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31527">
        <property type="entry name" value="RE64534P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31527:SF0">
        <property type="entry name" value="RE64534P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09347">
        <property type="entry name" value="DUF1989"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1989" evidence="2">
        <location>
            <begin position="61"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="321" mass="35767" checksum="FEF91EEE9AE435F3" modified="2025-10-08" version="1" fragment="single">MADQQTKSMSPADRARLEARKPVPKMPPAYLPTSGSPLAVDEELYRKIQQAPRVLDQEFLLPIRSGRAWKVKAGNVVRISTPEGAQVGDLNIWNAHNPRERFWASRTRQLHASHVSTHDRLWSCLPYMRPLATIIHDSLAWYGVDEHGGRVHDLLGTRCDPYINAVLSGSGSESGGTGYDYHCHSNLTRAVLEFGLGESDVHDVINIFQVTGLDEQGRYFMNPCPADKVDSLEFLAEQDLLMALSTCPGGDLSLWGFGADSEKEMVKCCRPLKVEVFRLEDEALLARSGWKPPTVAPYRGAHGMRIPRESPKVKSHSLLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5R8</accession>
    <name>A0ABR1V5R8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663307.1">
        <property type="nucleotide sequence ID" value="XM_066817615.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050675"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028322">
        <property type="entry name" value="PNRC-like_rgn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15365">
        <property type="entry name" value="PNRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="37454" checksum="3610BF5973F4783D" modified="2025-10-08" version="1">MHSSPHPKNTPGRRRPGRNGNSQKNYASENDAANYRQGYSDSPSTPQRLASGDALAAPNSQSTTQKQRKHSHKGRNKNGAASPGLAHANSVKQERHSPSFPPSQIPAFAGATFHHSPAPSALPIPSFLARTTSAPDSPSQVKKPITTGPSQEPSPPTTDSEEDGLGSPLPPVPRNEESPLEIFFKAQRAEKSGTARRASSSNITVIPPGPFSPPHDSPKECQTLPRVAALPPQKRPAAARMPSSGISSTELDGNPGKSLGPAFSTPYSERIKAARPANSSVHQAAPTGARNLDADRSDALKRYLFSGGNGASVLNGGSAKAQQMQSPPPSNAQSSEQMRFMEDSLRRVLKLDSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V638</accession>
    <name>A0ABR1V638_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663423.1">
        <property type="nucleotide sequence ID" value="XM_066817731.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050791"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="62"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="231" mass="25556" checksum="5E38F4BD75C00C5D" modified="2025-10-08" version="1">MPVKREASSGSGPPIPSKAAKLDELAAIDNIIARMTSYICDGNLGAVSSYIRAALALRGNRISQLTEEVDKLQRSLEEEGNVVQQLQEQNAALQQELNNAKRSRDECIKDTQSLIRSESALRNDVARAQDENRRKTEHVEKALTVAQGLCAGIRAWKDAQKNLQSTLSDDDTTAIDVGRANASETPPSYLLDPVIAQKIVEHYEHQVNRSVEKMCRHLADVEPDREVQDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V639</accession>
    <name>A0ABR1V639_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663424.1">
        <property type="nucleotide sequence ID" value="XM_066817732.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050792"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="99" mass="10892" checksum="1846D39567E7C786" modified="2025-10-08" version="1">MAITHPQGMRPQMPAAARIAATRSPVLSTRVLPALAVVGATYAVVSYVRNELGREQSTFDKMFDQQNTPEVMAARKKALEIEVNGDPRNNLLNILGWTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6F8</accession>
    <name>A0ABR1V6F8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662578.1">
        <property type="nucleotide sequence ID" value="XM_066816886.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049946"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="51"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="649" mass="75244" checksum="EBB69A2A3177EE2B" modified="2025-10-08" version="1">MGTRPGSSGAKKAEPSAFINKFLKTAMATVIKKKPSAEAEDVKEVNTATPESKLLVLPDEIIMMVLQSIQDNVSMLVLHQTCRRLRSLCEDATLEYQALSQLDAKPWWDDPYLKQICSLQDDELTEYGRLLWRDRMCGECKHLRSDANSYKQAVGRIYRTMRCSGCKTRHPLYLFSYGERQKASNVRVCIGRQGYFRFCKHVTLDFQRLEVAGTELEFVDCAQCASHRLGKRSYSHDNCKAHRRVILGAELQYHSVGVRSTFATCRMEWYQPVCLFWPVNMAETDMQSSLHDQLVKNIPKYMTEFIDINPPMTTCHHAGSSEFNVKRVSLMENQAPSNSHRTRATQSTCTSPDCEFRTSLLVESTRFEIRAVYKFSFTSATDPSWLRTLDPQSYLSDSDELTRGLMWCPNPGCATMRSGRTRDNLFRQQSAPSSWEQLLYKLPHTNRQMDQQLSTKAKEAAPDSMFLKIPDEIIINIIYDIDDRISFLMLRQTCSRLKRLCEDATFKYRLPAHWETDAQRPNPLQAKEGYVISPEEDPEYCRTLGRDSMCGDCTKLRGDPVLYKKKVDRMYEAVWCSGCLAYHPAYLFSLAERQKEDPDQRVCIGRQGYWRLCKHKTIEWRDIENYEKRAPSDSWWERVKPCLYMRHES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6V7</accession>
    <name>A0ABR1V6V7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663677.1">
        <property type="nucleotide sequence ID" value="XM_066817985.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051045"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="201" mass="22721" checksum="4F2D4010B37E8D2D" modified="2025-10-08" version="1">MIRQLKTLWVKKNSSIGGVLDTPVAVFKSFWAWFKSYGGQNSEEVVPACFPNEHTTINLEFCRCLAGCHARSNRAEHAETLSAIFHSAIRSLVNIQHNLVMDSASPPLRFLGGKHQYRKALGSVNQERLDSYCSKMGACKPLPISILYKTGDVCIKYRLAGRPDLRAALVLKSIYYQQKQLGGTRTIWNTLWTTIIKRFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V828</accession>
    <name>A0ABR1V828_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664105.1">
        <property type="nucleotide sequence ID" value="XM_066818413.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051473"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="73"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="215" mass="23734" checksum="AC4969C0392EB701" modified="2025-10-08" version="1">MAALKFREGTEADADAVSNVFSDSFSEDGITKRVFPATSEGARASIKDWLGGGLKDPHSRYLLAVDDSKSGVENVVALAKWVAPSAGPKAPEAEDWAAKMAWPEDVDAALGKEFFTMLEKKHKEHMGTRPHWYLELLAVRKSHHGKGLGKHLLNWGLERADKDGIEAYLQASPAGVPLYRKYGFEDIETVHVKRADNYSEVFMKRQPRPSPGASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAA8</accession>
    <name>A0ABR1VAA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_013983</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663989.1">
        <property type="nucleotide sequence ID" value="XM_066818297.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051357"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="6"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="265"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="333"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="366"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8067236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="522" mass="57110" checksum="46BA279EAACA9E0C" modified="2025-10-08" version="1">MSQSQNSRLSSLPNELTLQILGELDWRDVRSITLLNGDFRWRFVDYWFDVCYESEVNSKSKSEWCVLLFCHAVKTNSSEIVQYLATRKNDLDLTGFQARQRVDYPWVCANESYLHMAITGDAPYAASFLVKLGSDVDGDIGHCPDLPALCLALARVNMSSQRERDTALRIACSNTLPRIAAHLLAKGADPNSVSPFGLGALHVTLMRRPLPSIVHGSQRFIAEFDVYSLLRLLLDYGAAVDLPTQTTRAHICGPQCWKSMQCDHSGQTGLHLAAASGFPMCALLLLDNGANHRHQNAGGYTALYTALCQANRGVANILLKCSSEANPVVKFPQGVTTLHIACRFAYTDMANAILLRGADVNATDPYGNTPLHEALCQMGPGRTADVVETLRLLAEHGADPDISSRAPTPRQKAEAHPSYAVREMFILGKAKPSRILPLAASSEVREPSNSSSSKNAGGGPKPVDKTEHVIRGFGESPRKGHSPERFHVSILRYPKVFPLFTGVGPGRQSTAEVGVRFYIILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHU4</accession>
    <name>A0ABR1VHU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664578.1">
        <property type="nucleotide sequence ID" value="XM_066815288.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048348"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="955" mass="107739" checksum="7D1DDBC9714BC7A4" modified="2025-10-08" version="1">MSVSHLVEQYPAPDQSQKGIDIILVDGLLGGEPGLSNWAEPLHSRLLSQSMNSAIQYLDLGIKLEKLEDFPRKMKEAEEILLRELYQFIKVLCIAHDIAEQEHRAKLLMTNVSQVVLLGTPPATGDAVKVMKTINIIICQRSLAKDRLGELADVQRTIDDIGISYKERGLPSRSVVCVETQKTKYGHRDLKHVGRHKQRVLVDAAMWVSRFPDLAIVETSGKLSSAFETNMVGEIIELLRQASPQGLSQLSDGPSTRSRSNWAKSRWKRAAHWAGRHDSGLVSEELVVEVPRYYNLPPPQRNLVRGRETELESIHQYLQRKVDPMDTLIPLRAVMVYGKPGMGITALATEYHTIATSLLYILEIVDRNSNNSEANWSILEAWLQNPLSVKSTNREKRFDAKWLLIMEDVTVDTNILDFWPRQGDGSILVLGKHPAPLRDETIDITPVELPSLPENDAASLFLSVAEVTHPVDQTVLDIVNDWECIPAAVIRVAMKYRNRKQRESLPEFKAYQTSNRKDLLLRGVSHMSSIAALWTLDGRSSSEWSILSVLPFLHHAQIPEVLFSNYLEPTETSELPGGYLTSRRRLEVDRLIDVMEPGHGVNETTISTDKVLQDSIRVEYLESGDDLAIAFNRASSMVNRMWPKSITAEISFSELDERGRWKTCQKLLTHVKRIAGSYVDLDPDVQRDCAQEDFIKLMIEAAWYLNQKGRYNDATKLLDVASLALRRAPREMLDLLSALYNTGTAIASTANDTATALERCQQFKEVQKRIFRSSGVETVKLAAAYSELGMAYLQTGQASAAVWRLLQKSRQIREGLPNFEKVNLFSVLRGEAFYHLLHREYDEAETKLLEACEDRRLKYGTDDRRGGRAGALLFELGIVIYQQSLQVSDKKELERLLKSSTDYLERAKAIFSHVDIQYIAEVADADVAIARNVLASNADKVQLHKAQQVSPSIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIF0</accession>
    <name>A0ABR1VIF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664819.1">
        <property type="nucleotide sequence ID" value="XM_066815529.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048589"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="424" mass="45045" checksum="3DE97E372C057D0F" modified="2025-10-08" version="1">MAEELLKRAAASFPNWTNTPIPRFSVSAGGVIALADLSTIAQRTAIAGGSSWLDALLLAPGLHYQQAADALANSGSSGMDNSTGGGSSPSYSAIEQLREGKTSTYNITNPATVRYLQRMAAAAQRDGYPVMVDVGTLPERRYWSGGRGRRSVGQRANIWKDQPADLGWVSHLLYLASPILTIAAFVFMILLQEWWGVGLLLALMLSRVLNIWVIKQRAKLPPVLPKDGAAKKPLPPPSAPRRRSDAAASSSTTTSDEEDKDEDAASPGPHHHPPENLGDVLTSYLVDLGAGRTVCLRGLADDLQAITTTTWLAAKTHVDGYLEAAAKLVVYVVAAFSGNMSQVGGLIFMALLLITAGLLGLSNAHAKTLRMHGRVAAPTQERLVLVPMAAPAGGLYHAEHGVLVVGAMALHSEDAAERWRDVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIQ7</accession>
    <name>A0ABR1VIQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">R3H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011331</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664936.1">
        <property type="nucleotide sequence ID" value="XM_066815646.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048706"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02642">
        <property type="entry name" value="R3H_encore_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051937">
        <property type="entry name" value="R3H_domain_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024771">
        <property type="entry name" value="SUZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15672">
        <property type="entry name" value="CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15672:SF8">
        <property type="entry name" value="PROTEIN ENCORE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12752">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51673">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="3">
        <location>
            <begin position="291"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="SUZ" evidence="4">
        <location>
            <begin position="355"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="541"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="710"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="420"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="604"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="734"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="758"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="787" mass="85209" checksum="0ED5B9EAA8F2A27A" modified="2025-10-08" version="1">MLPYRTSAVYVAGPPRLTRYQVAASGAKENMPPSTAQRVAVPAGAAKNPAATAPKAVSPTVVAKSAMHHGTPEAAQKDSRDERKSTDATVKVTQNMNDLNVSSKAVNPASTPSLVVNGSSNLAPGDSHSKVDSTTAVSDEVSNRADSNSEIGTKAPSLDGKSITSGTTFALDEKESLRPDDSASVKAAEDDEAFSVRGSQMTASRMGSEIARVHRLRLGDMPEKRIIQLLPEVVVEQGVATPQSNSSGIPPPAEKQQILANVSQNPDAFNSMYAQNPDEKLLEAMASPKDRLFLLRLEQDVINFVQSSKEPYMDLPPNNSFCRMLTHKLADYYHMTHSFEAVQGAVRIYRTPFCRVPPSLASIVGTAAETNNSSTPPVLLPKKIMRRGEDSGNASNSPSKGTSEVGSDGEKKNQGINYKLTREQREEAYNKARERIFGNSEKTGESTPETEDANGMSRASSVSGKEKSNLGRRGKTGKQRRDDSESFDSRSQYTPYYGTNPHQPSWAQTGQYVAVGNMPYNGQMQQLYQAPMPQGYPQAGPAYPQMMPQGPMSGYPPLLTCQQYPPQPPQPSQQRYPPSNGSMPGYGSPMQPTPAQPAWQQQPAYPPASSPVPSPYQQPATRGPQSQSNVGPVGIPYAFGQLPVNVNPHDPKSQHPIPGSYNRHAFNPKTQSFVPSNGMNHVQPPMAPYTPQPPSPIWVAHRYCMSRQSSSNSLPAYHPHATPPQHMQQHPAAHMPHMPQQMGHPMQHKNMGLPQPMSGHNHQAGYSTLPNYGNPATLPQKPPTGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIU4</accession>
    <name>A0ABR1VIU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011333</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664938.1">
        <property type="nucleotide sequence ID" value="XM_066815648.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048708"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="676"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="712"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="39"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8071130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="860" mass="96507" checksum="F891C1FAB3F387FD" modified="2025-10-08" version="1">MRTPFICRQCLSRFQHTPARSQHILRSAYHDLARTDQAEATAWPPPNPNNNRFDPGAVDGGSSGSGEVSSDSQQNYFRRYIPDSKNHIGLASGSNPRIRLKRQILGTRGDLVYLQSTLADTYGLSRPAARDAIAQLKRLLFGCNPLHISDRVDEFDTWKAAYASVLYTSLQDPLLRPTTSENPEWAALSHDQDASVETMRTTWLEIDQAQREMNWGRMIISALQVNPKLLAPLLQATYDASWSPSYIVEDVARLLFRRAKVSGTSEQQSFVDLMFFLLDSSPNGHLMLGEDVLASIISWANLEQVVAIFQYLRSSMPRLTPSTLLHLAARFASSSDHKVLAAEILCYMTELKGFDINSPAAASVCTSLLNVKRGLPAPQGDAAPDRLFKTLLEHGLRPNLLNFTALMRNFAVSGHLETAWTVFELLGQYGIEADDQVYSILLNASKKENDVSSIRRVIESVDVRDRGRPWNVNIANHLLDILYRDNEGQNEVRRAQRKRNNAFRLMLQLYAKIFRLRPLQKFLPFDIEELLLWQGPPAKYATATTQMARDVPPQTIPLLADPDSTTLALMITAHYRSLEGPKQIFQAYKHYNELLARRDSHATAVAQQHGTLVHDMFLKAIMQFRPYLGYAVRTVQGMLVRAEEEESRQCERKRDHGRTTTAAIADAVVKKHPYPSVYTWTTLINGFRNHRLPDPAFSVLRMMVQEGRVQPNTVTWNALIGAYARVGDAESAVRTMRYLEAAGFQSDRYTVRAMESLPRKARERAVELLEASKAESLDEARADLVKLGIDTALPPSSMSAASSASGLEPPLDEAKWLPATAMGDQSRTAASMVTHTVFTACLNMNTREPGEKDQVIYDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ63</accession>
    <name>A0ABR1VJ63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665066.1">
        <property type="nucleotide sequence ID" value="XM_066815776.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048836"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="133" mass="14791" checksum="E7FD48456FC8D8AA" modified="2025-10-08" version="1">MSGAATYHARRYRTLFTPDALNFNASPARAAYTPVYRPAPTGIHCGLPKAAARNSRGLLMISLPIILATAAVTYMERNLDQKREGLQADLKPQTSVAQETARRKALLDAYGDRSSLERLEEVMMVYEMTKDQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKJ0</accession>
    <name>A0ABR1VKJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010601</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664206.1">
        <property type="nucleotide sequence ID" value="XM_066814916.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047976"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006838">
        <property type="entry name" value="ADTRP_AIG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10989">
        <property type="entry name" value="ANDROGEN-INDUCED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10989:SF16">
        <property type="entry name" value="AT02829P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04750">
        <property type="entry name" value="Far-17a_AIG1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="209" mass="22583" checksum="5D435052886FB1F2" modified="2025-10-08" version="1">MSHRTRLSLPIYLAGLFSFAATFLWLPHTTNPLHRGVGGPFQFLTVIALSLSTVVFTLGLAADINRTWSTTLSSLKAKLSALCATPLALLVGGAVLEQSRGRRGAVDTARARGAVRAGLGAPCGAGRGVDFGLDASEPSPVDHERQVGAGMMLTYWGWLEYCFSYNGWYPYPGLEKMSRSDMLITCFASACLMAGNTAMLKYLYRHVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VL91</accession>
    <name>A0ABR1VL91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664808.1">
        <property type="nucleotide sequence ID" value="XM_066815518.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048578"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045201648" evidence="1">
        <location>
            <begin position="20"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="153" mass="16236" checksum="1B2B245A517A0231" modified="2025-10-08" version="1">MFSSVATTALCLFVAGAAAGGDGSGGEFVDEVRRDFKMGLFPRQQVLQDDIQPFSGKLGGFSAAAITQSQDKKRPFTVKGDTFTDFKTAAQRACDNQKNDCADAANKNKNAGFKVSDCDKQNNECKDAIASATLTSFAVLTSSTAEFDIFCEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VN48</accession>
    <name>A0ABR1VN48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665091.1">
        <property type="nucleotide sequence ID" value="XM_066815801.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048861"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="464"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="541" mass="59459" checksum="C3F2E4800A15C756" modified="2025-10-08" version="1">MDAQARRRLKISNTWMQGCAVFCITALFVCIIFFVQSVFDAQARSDQEKPLNPIHKIDASRTLSLARTAQAILSLSTTFALQNTFQYLQWAMLSRPQGLSYTSMLSLSTTTGALSMMNLIRSLGTNGSSKAWAIMRYYHDHTNGISVDTVYETALSYNVTAGVGPFNGSLVRPFLGFLDSLAPDYPYTTVPYNYYAMAGGLVAYPTFGVVAEPIYCNGAGCFSYLLTGGLEMAIPAVPQGYPEYPLVRIANAPAVQMEFTHRKEYEDFNKRDCSVFGAPGTPIGIQLCLAQGPKWGGLQAAIFSCTHGTDGGECLGDRPLPNITYGIKLFSRQASIIASQSNHSIMEGEDLTEAEVLPPIDLLAYKVSLDWLLNFTAANIPAATSIAANFVITNNQVPDPSADGVLSRNFQSILAFPLWLFNANNWGNIELKANTISPTLLPQFYTTATIVAPYSKIGFNRSMFYLFIVFQGLALSLIWAVLIGIWVRSTPLPYISSFPLFDAAFKLEKQELAQDQTVVFKAEDTHVLELVGQYRVFVRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUJ7</accession>
    <name>A0ABR1VUJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">A to I editase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665864.1">
        <property type="nucleotide sequence ID" value="XM_066813902.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046962"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002466">
        <property type="entry name" value="A_deamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042935">
        <property type="entry name" value="Tad1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47803">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47803:SF1">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02137">
        <property type="entry name" value="A_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00552">
        <property type="entry name" value="ADEAMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50141">
        <property type="entry name" value="A_DEAMIN_EDITASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A to I editase" evidence="1">
        <location>
            <begin position="82"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="459" mass="49668" checksum="A08D1477E53DC385" modified="2025-10-08" version="1" fragment="single">ATRSRRNSEDERICFHECHPGYYSIARAAGIREAPCKAKAPVRDNGIHEWVPLSGIVAELRGNDLRCLSLALFAEITFLSASRRTGMKCLPQAKLPLARGNVLHDWHAEVLAIRAFNRFVLDECKVLAEGGPDAESLFLRRRRVDELQEVVTTTTTTPWCGQPFAWRDDVKLHMYCSEAPCGDASMELTMAAQADATPWEVPPSPIAAEPTPTAAPLLPGRAYFQHLGVPARGDAPATLSKSCSDKLALRQCTSLLSSTASLLVSPTNAYLSTLVLPASQHSVTGCERAFSARGRMAAMKEKTEDLLAGGYRFAPFRVDTTDLEFAYSRRGVISRLAREGGVVAAGVGADKMAASNLAVAWTASGLEEASLGGTLQGRKLFDPRGASFASRRKMWALAAEIASMLGAELVGLQKTLAAQNYAELKQSGMLQPRMDVKRKATSIALKGWAKNQGDDDFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV27</accession>
    <name>A0ABR1VV27_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cyclin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009767</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666044.1">
        <property type="nucleotide sequence ID" value="XM_066814082.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047142"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20537">
        <property type="entry name" value="CYCLIN_CCNO-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20559">
        <property type="entry name" value="CYCLIN_ScCLN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="92"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="7">
        <location>
            <begin position="187"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="190"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="302"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8075104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="332" mass="37635" checksum="1E4B86A39E28AD01" modified="2025-10-08" version="1">MAYVNNNSTDSGYFAGPDELQNLRLPSRETAKLLARNRQDMIGNELSRLTGEEYLEDIMQHMRHMEDETLPDANLIDMQREIQWFMRPYLVDFLIEAHAAFALLPETLFLTINLLDRYCSKRVVYKQHYQLVGCAALLIAAKYGDKKDRVPQINELNNMCCGLYDSGMFTQMEMHVLNTLEWAIGHPTVDFFSQLIVAEEADDREVEHMAAYLCEIALYHREFVSTKPSIMARSSLALARAILGRPEINDGEWDQVENATLLALSQQLHQPSITLSRKYSSPHLSRVSGRLSDFLAQQAAISRRAEPPSPPAEPVVAAKASSIYSTPQKVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVH8</accession>
    <name>A0ABR1VVH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666195.1">
        <property type="nucleotide sequence ID" value="XM_066814233.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047293"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04336">
        <property type="entry name" value="AmmeMemoSam_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060:SF0">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="328" mass="36260" checksum="30E6C9E0F7FFF1BB" modified="2025-10-08" version="1">MSGQQVGTRKDSHAHSWYEGEPDELSSTLDEFLAEVPSDIEGKILPIKGARTIIAPHAGYSYSGPCAAWAYKSLDLSNAKRVFILGPSHTYYLAGCALTTYAKYATPFGDLTVDTAVLQQLRATGRFRDIDRRSDVEEHSLEMHLPFLYKRLTQTFASEAEYPTIVPILVGDNKGPEEKVFGALLAPYLADPDNVFIVSSDFCHWGSRFSYTKYAPENKLENLQSVTRSMGAVTNPPIHESIKMLDQLAMDAVESGRHDDFVDNLARTKNTVCGRHPIGVTMAALEVLAKDHAEPGKHKFKFVQYQRSGLVETANDSSVSYASAYAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWU1</accession>
    <name>A0ABR1VWU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DMT family organic anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_010335</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666612.1">
        <property type="nucleotide sequence ID" value="XM_066814650.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047710"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="10">
        <location>
            <begin position="94"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8075672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="420" mass="46036" checksum="DA3CC4AFAE4F3943" modified="2025-10-08" version="1">MAVNRDSNDADRKLESGTATLPAEQKKDGGLHPALYIILWIAMSSSVILFNKWVLASAKFGKCPRAHTKDLRTPQNTLMPDADRRASFQTSVTMFLTTWHMVFSTAMTQLMARFTSLLDSRHKVPMTAETYRRAIVPIGVLFSLSLICGNLAYLYLSVSFIQMLKATNSVATLLTTWLFRIAPPNLKVLANVSVIVLGVVIASFGEIKFHLLGFIYQIGGIVFEALRLVLVQRLLSSPDFKMDPMVSLYYYAPACAVINGVLTAFVELPRMGWADISAVGVPVLVANAFVAFLLNVAVVLLIGKTSAVVLTMSGVLKDILLVMASMALFRDPVTAQQFFGYAIALGGLVYYRLGAEKMQAMAADARLQVAQYRQRYPGRLRALLLAALGGCGVAFWLWGPSPLGEYSEYMTTRPPAIKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX02</accession>
    <name>A0ABR1VX02_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666672.1">
        <property type="nucleotide sequence ID" value="XM_066814710.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047770"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848:SF1">
        <property type="entry name" value="SUN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="414" mass="46375" checksum="23233C5FD4044BB4" modified="2025-10-08" version="1">MGKPSDTAGAASDAVSLHTNPGQSLGNDYDHQDAPELDIDGIDDLPPLYSDAVSSGDLNEPLLPASDSTSQEPSSLCQPFQKDCNSGAAYYVDQRLESPKVLEQHLRHWAAAPPRPYIKIVGTHRQTEKRSNNKSETKTITDFDVAIEMTPYLYSNAQYRKSWSQLRTVDNGERARRGTILKKCAPGAVQHIEVGGAQKPTLEEWCHRFCANHGGLKCFSLRREMTGFDFASVQQKLIKLVRDTNYRGQLSIYMQTRDGLVEVYNDAHTNRWRLTSWIQWVFYLTLLFLFSWPYLWLRTKRFEVAVAEWPFSRMAAGSGAEAGASSLGSSNSSGREYVSISEEQWYNLWARAVLRAVMEKRQTVLDQADLRRAHEPQPSFESGNATVDSAVGFVQAGIGAMNEVNRHLGWGADC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXD7</accession>
    <name>A0ABR1VXD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665494.1">
        <property type="nucleotide sequence ID" value="XM_066813532.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046592"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="22975" checksum="7A4F9FAC6D90814F" modified="2025-10-08" version="1">MSYLANFRASKANRMLQKIARVLQFISAIVSLGLFSRRLKAILTRSHDYNRSDGAVEGILAAASLYSLIATLMQFALRHGAPKVLRWLLVLMDILFVGAFIAVAVLTRPHGGSSGEFKGACARPRGVNGLVPQSVRNQFHCRLPLGTFVLAIISTLLHAFTAIFHEIRDKINHHRASDNENLHNEGPGAHGYMTKEEKKQAKRNGLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY67</accession>
    <name>A0ABR1VY67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009954</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666231.1">
        <property type="nucleotide sequence ID" value="XM_066814269.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047329"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF25">
        <property type="entry name" value="MAP KINASE KINASE PBS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="250"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="600"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="630" mass="65496" checksum="3A5487E1EA851447" modified="2025-10-08" version="1">MADTPSPPGSPLDTPDTPGPDEFISNDDIIPKRMPSLRSISDPQNPGQSMSASSTPLGVLSNARRPPVSTGMSSGRLPEDINAKMRAFHLSRQGSNPMAPTTPSSAPPQSPTAAGAGAAGVPVMGGLPGGLRPPGGLQRPGAPSFPKSAPSLPPSAGGGLAGKRRFGLKLGDMGGGGGPANPAAPNSGAAGNNAAPANNLSTGAPSQMSQFANYIDTEKGYLTFKGKAIISNKGVDFSDGTVFRISLDEVEKLDELGKGNYGTVYKVRHSKPRMPRFGQGLSGFKSASNSALPAATSEQDDAPPVGGGSVSGKVMAMKEMRLELDEAKFGTILKELLILHECVSPYIIDFYGAFFQEGAVYMCLEYMDGGSIDKLYTGGIPESILQKITYSTVMGLKELKEKHNIIHRDVKPTNILANSRGQIKICDFGVSGNLVASMARTNIGCQSYMAPERISGGAFMSSGASDGTYSVQSDIWSLGLTVIECAMVSSTIFSQLSAIVEGDPPDLPDVGYSDTARKFVHACLHKVPKMRPTYGALLASDWLQGLAKPETITEEDEEAAENDASDQAITDAADKLKLGKSGTTEDAEIAAWVQGVLGGKESGAGSKSSKPALHTAPLDAVSPMASPQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7F5</accession>
    <name>A0ABR1W7F5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007221</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666878.1">
        <property type="nucleotide sequence ID" value="XM_066811536.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044596"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF2">
        <property type="entry name" value="ACID PERMEASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8079403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="48438" checksum="E61D88A84808F22C" modified="2025-10-08" version="1">MILMQSWEAIFGVGVLGLTNGGTAGYIWMYLVSWVGFLFVNVSMAEMASMAPTTGGQYHWVSEFAPRKHQKFLSYIMGWMCVLAWQTFVASTCYIAGTQIQGLLVLNYATYEPHPWHGTLLAIALAAFGVFFNIVLARKLPLVEAGLLSIHVLGFIAILVTLWVLAPRSPASEVFTTFNDGGGWGSLGLSTMIGINAGIIPLLGADAAVHMSEELQDASRSLPRSMIATTLLNGTLGWVMLITYCSTLGNLADILDSPTGIPFIAMFYNTTGTAGGTTAMSVLIIFMTVAGLLTQGATASRQLWAFSRDKGMPFSSWFAYVYPRLNLPVNSIITTLIFTILLSLIAIGSPIGCVLWRRVTNQPLLPSKFSLGRWGLFVNVVSMMFLVLAFVFSFFPPSPRPTPDLMNWNILIWGVSVVGSLVYYAVRARKQYVGPVEYVRKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7G5</accession>
    <name>A0ABR1W7G5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycan 1-3-beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007239</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666896.1">
        <property type="nucleotide sequence ID" value="XM_066811554.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044614"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00306">
        <property type="entry name" value="Peptidases_S8_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039279">
        <property type="entry name" value="QRT3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928:SF2">
        <property type="entry name" value="PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928">
        <property type="entry name" value="POLYGALACTURONASE QRT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="6">
        <location>
            <begin position="293"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="6">
        <location>
            <begin position="606"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="5">
        <location>
            <begin position="2094"/>
            <end position="2239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1097"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1766"/>
            <end position="1804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1890"/>
            <end position="1924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2333"/>
            <end position="2388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2420"/>
            <end position="2444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1770"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="2358"/>
            <end position="2369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8079421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2693" mass="287769" checksum="8036F9424634F2B9" modified="2025-10-08" version="1">MSNSSAISVARHPLTTCGPSVQAERQPVSARVPFAFHHKQKRGRNVGKRELTEKHYRRALGPPSLPHHVFHYKRDWKGQRIWLQEETAYELKDLKGDYNTKAATYSVSKPPKHPGRHVTVLQRPIEPLSRLLGLAVRMAFATILAALLLFLAHPHNLVVASWDGLQDSAQNWPSVPGYGPQWPSPFAQPNAPYMVDNRHNYFNASPDKGTQNGAVWQYSGSFENFMTNLRAGNVIRGSDGSGVKPGDNVTSAWTNSTLVNSAHALRSDSSSYWLTKLGPLGSQPLAGSDYKFFRNVVDDYHADSSGATDTTESINAAIQDGSRCGNDCGNTFTKGAIIYFPPGTYKICYPIIQLYYTQFIGDPNDPPTIKGCDTFKGIALIDTDPYIPGTSGEQWYINENQFFRHIRNFIFDLTDMPLSTTDNGQPYVPTGIHWQAAQATTLQNLVFNMPNATDVNTASHVGIFMENGSGGFVSDLVRQTPATCIVEINGGAIGFNISGRGGDKGQGTGSVSIIDCTINNVPTAILTNGLEGSPNIVLDNLWVTNVSDIVAQDDHQTLLSEGPGPYNVELWAAGKRYTADEGWYKAGPAYAPPKGELDSSSFLVATNEGISNDGSGDQAGAINAFLAKAASSNQIAYFPAGIYQIGSTVLIPTGSRVQGSSWSQIQGAGFYFADMHDPKVMVQVGNKGDVGNIEIVEMLFSVAGPTAGAILMEWNVAAAHQGSAAMWDSHFRVGGATGTDLDVEHCPKSGGLNAQCIAASLMFHVTQQASGYFENVWAWVADHDNDFSTASLTDKTAGQVSVYGARGMLVESEGPSWFYGSGSEHSVLYNYQFYNARNIYIGHLQTETPYFQPEPVAPAPFSQGKSFAGDPTFDHCTTDTCRMSWGLRIINSNNVTVHGAGLYSFFNNYDQDCVDTHNCQERILEVQGCVSTVVFNLFTVATTDIAFGVDNAAIHQNDTQSGYTTEVSIWLPQNGQDTPQIVYVGTEIWETPSVSCSPPCILVLPTSSLLTSSTIDPGNYTTSLEYGSPGTTTIGSGQVITTFIITTTVVTIDIPLLTIGGMPYYNLNVTSTATGGGFVPEPSVSIPPVGVPLPDGKGGTTTRNLTLPPWPKVSQGPPDGPGWTMSSDPFDFPPPQPAGSPASTSSRTFTFFTPYTTSLSIAGPTVITINFPPTLIAPKIITAPPETELTFATPKMTFTFDSDLQTTFTVGYECPPILIKTFLNGYEGILTADCSITTAWRWPLSPPPAATAYPLTIPPDPLALPPGIFTFPGGVGGATTTAFTLGGYGGGDKPITLSVGDTKGSLSPVIFTLPPYGIGTQSTTTVSPTSTTLTFSGSASGAQPTILTIGEVGGGTSPATINVEGAPGGVAQTSSLTFGGPWPPGTTPAKPPGIGSPPRTMTFGGFGGVQPTWVIAEGTGGGAQPTTVTLQGVMGGPLPTTITLGGVEAEAQTTTITMGGGFVIVPATTTITLSQPSDIIDGPNPPTFTVVGGGGWVQTSTVTLDGVWRGWGIGHPMTDPPIEEPAAGPKPTMINLPGGYTPTAITLGGGADGAGFQPTTISLERGGGAFPTTITLGGDDNGQTNPTSVTLPGGWGFWGIPDDATTTTSSSATPGPPLPVWKHWPAAELVAIRKDDPDPHEDGTTDTDCFYILWIQICIVINIDLSGFKWRFPPGIYPPGPPPWGILKFPDIGTFKFKDDPPPWPKITIGWDQKLTYSDERSTSCQTQTAEFCSIMTSVMIESSTTRRSTITGDCATLTGCSEPARTEEATTTSIAPTASTTASSTSSISSTSSTSSTSSSSACQPTASGNVLVCYNDAIVYPVDPANVGEIPDLLVNYTGKYQTVEAAGLTGFYWVPALDLETYGKLMASPDVDGVDYYEERNAAYRGVTDTHDPEDDYPSVPHVATGATSSQPPQPTSNGDKKLVSREILGSVGDFWEMGVGSLPKKEPFCGQNSFTCQLYNGYPAYTYWWDTYGGWDATNNQGWAVYVVGEAGIYDTHSEFESSSIQHIRDNVLYGHPPVDPTIPNPQAAHGSGVISHINGKNLGTCKQCRVVWTLELDWRDFPDFDPAGAQELAEFYMVLNDVNRNDGALKRKAVVNCSWKSDQGYVSPHLIRAYHKILKELDKAGVVVVFAAGNNALTHGKEINQWPTLLASPRKSVNPYGQLKNLIVVGASTSNGTDTEWGQTASYMTTFAPGQDVELPWDPAEAGANNLYFQFNGTSWAAPQVAGVIAYLRSLPGPFRKPLREPKNVKKMIQFLARRYDVLNFDGTPVPVDYRDKRPVLWNGHVQVWDYANERVTTYNCLKDWDTRQGWDFHGACEGLDPDMKNMGSGESVQACNAPEGPSKKKKLRRDDSDDYDYDDEFDADSCPLDPDNPYDPGAPSITFSSASVAQPTCIAAGGCGGTVCSGYYCAPSPSGTPPDHQDPQDPGNGQPVSSSTLEHRPVAHEDFVVLVVDGNSQPHGALPPPNSVSPTVNCDPGDDQCKVDMGYRCNCDKNGCDEWSPACCATKSCPNCVCFDGRCTSDSPKCCPDTCVWSWTGGYGGDKMVAISHMLNDRLASFANSSAGSYSLWSHTNDTGSWNLAGYNGRLTPASVCTETPAWSPSLGHDCAADAKPDQVGLQTWYANMTVFNDACSYLSGVSNYSSVAAGVKVGALTCSRWATTDCYRANHTDVHDCGTDKVAEELVCQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8S3</accession>
    <name>A0ABR1W8S3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007265</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666922.1">
        <property type="nucleotide sequence ID" value="XM_066811580.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044640"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF103">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE MULTIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8079447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="429" mass="47089" checksum="1C08FDAF1B9E890B" modified="2025-10-08" version="1">MNMSAGSPKKLATSATFPPVKRGKSRERDMPKQSDLVDYNYAVAGHAGTLCDADGELFIKPCTAPEINFYESAHALHPDFAEWMPLYLGSLALTENTTDEMIHAAIPGIVEQADIPTPIKEEIQSHLHLDERPIPPALLQRSATMGAAPLVIPSSSEKPSWVPNKSRKITTDRAVVLENASFGYKKPNIMDAKLGLRLWADDAPAEKQARFDEIANETTHKHNGFRVAGMRVYKGSEDPKDLDKEGYRIYDKWWGRKTVNDDNLLSSLKQFIFNKAAGIDEELGKIVAGAFATDLRRVQEVLEAHESRMYSASLLFVFEGDGAALRAAIEETSASAQASINAGIRVDSGIGMDEVGSNSKMYVSLDEADGGDLGGEESEDSEDYSSMPHIYSLKLIDFAHAKWVPGQGPDENILLGVRSLVKLFEDMSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W986</accession>
    <name>A0ABR1W986_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667517.1">
        <property type="nucleotide sequence ID" value="XM_066812175.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045235"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045715047" evidence="1">
        <location>
            <begin position="19"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="163" mass="16827" checksum="4350671FF4288EA2" modified="2025-10-08" version="1">MHASLVALVSTVAAAAAAAPGYSHGSSSSSLTAAARDTPYAEWLATHFAESCSPGGCFASFNISAPAGYVAGAPAFDVICHLVYARQDWRDCDNSGVQGAAGGSRVQSMKTDASRRGLVRISVAHIWTSLEDGRQRDNASGFAEVDAGWSVFSVPVTMLSAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W989</accession>
    <name>A0ABR1W989_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cyclin-dependent kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_007869</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667526.1">
        <property type="nucleotide sequence ID" value="XM_066812184.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045244"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039198">
        <property type="entry name" value="Srl3/Whi5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28246">
        <property type="entry name" value="G1-SPECIFIC TRANSCRIPTIONAL REPRESSOR WHI5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28246:SF1">
        <property type="entry name" value="G1-SPECIFIC TRANSCRIPTIONAL REPRESSOR WHI5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="192"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="344"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="260"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="284"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="487" mass="51530" checksum="F151461B42B5CCDB" modified="2025-10-08" version="1">MATSEAVQGGPPLVHPATAASSQSQPLQDSSNDESQDTTASHDTDRVFTPPESDSGSSIAAGNGNTSSQESQLLQLSQLAAAQEKMVETGISKKRMADGVVKHTRNGSLTSPVRMPGHSRNTSTVSVASTATSRMSEVKSPNLCRGALGIHQVTDHQTALQLSAELKTKLSYAMLKVNNGWQSHSIDEVESLASQAASPTSSSSTLHGRHGASASPRPHKPGAPGRAHESFWRESNTRPRLSTSPPKSQLPALAPPASIQPRQPNHLNPRRNSNAKYTPAFLSPTHQGSPHTPAQPSPLQSTPGTYMNRTPNMDPIIFSPHQNVREQEALETLVFMSSPGNSANLKHGFPSSHSRNGAANSHRTALPGSRLGPGADGHQVRKSLPTGRQGKRVGFEKSPGTVDDMDMDEAYGSPQIRGTPRRKTIGSKPSLSVPAGLSGPSRSRPALQDDDIERMLDRVAADDSSDSDGEITLPRSRRPGSAGVVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9U4</accession>
    <name>A0ABR1W9U4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008092</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667749.1">
        <property type="nucleotide sequence ID" value="XM_066812407.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045467"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368:SF1">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046387508" evidence="2">
        <location>
            <begin position="22"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="31333" checksum="A9F3056799A69E56" modified="2025-10-08" version="1">MPSVSQALVGALVLMVDFATATLREGVLPAYHYGAPIPVSCMNRSTETGEHIQDVHDEIQWIPFPVCNETSKPLEFHYGTESEVNCTVAMIDDPFFHLLEFYIHSDAPLACRLPARPQPHIEAQEYIPLVFALAGTLQKSHLHISTHLNVLLHSTPKHHVHPHDSGVLDSGIAYSTSPLSHMDGSQTKRLVIGDPLPLSLSVRWFPTPALPKTEGKVEWAGMGGHVYASTIFYGLVSFTAGVLGSAVYFFGVVLPKRLRGRGLGGATPLGYGLNGKGVGNGWGIAKRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB67</accession>
    <name>A0ABR1WB67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_008564</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668221.1">
        <property type="nucleotide sequence ID" value="XM_066812879.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045939"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="66"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="393"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="406"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8080746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="547" mass="61126" checksum="CBAB925590AC76FE" modified="2025-10-08" version="1">MSASNSTPKSPRASTGASDLSLELPGPPPKYCIPEIEREGLEDVERYDTGGLHPVQIWDLVRDERFEVTHKLGQGGFGTVWLCRDNREDRWCALKIMASAQSSEEGGDVKVMNHFREKGIDPQEAAAHHVVVPEEHFWINGPNGRHLALVTPLLGPSLAYWLEEQRTTFDAMTGFCRQMAKGLQFLHDHGVCHNDFRPANILLKIRNIDSMTADEIFELFEAPDTVDISLTSGEESSPHAPEYLVKPVRWATAMEKGIVLEEIAIVDFGEAFLEGQPPAFSGIPMVYTAPEIMFNKTPSTASDVWALGASIMEVYGGRFFADATLLATQVLEKSLGPLPLEYREEFESQHRAYLTNLRAYEDLCERNLLKQGLTELINKNPPKTEPSEWALTAEQRTDPSHPVSYSPVTQPEANSQEADSEEGYSHPFTKKLSTPKFGFFKGPDPRHNEDGIWYLSRDEILALTDLASKIFLYDTQERLTAAQVLGHTWLKEETEEEGVLGLGFLQRAVESLSPILVVLPLLFGLMQFLILLFSWPCSTASIGTGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBJ4</accession>
    <name>A0ABR1WBJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667024.1">
        <property type="nucleotide sequence ID" value="XM_066811682.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044742"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="502"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="706" mass="79930" checksum="E0F5E4BC261462D7" modified="2025-10-08" version="1">MPREARRRPKKSEETWSDPHTSDESDSDSGSDSDSEVDTKAKEEKTQKEHAQVLEGVEVMALTKNSSGASEASKLGYASKLVSNWYHHRCQYDSCQVRWSEFAVVDEEEADLQKRALQVPIVHRHEFKNKRWITSDITVQDEAMRKVLDKVLNKYQDLDLEVINYTFEPPFMPLVHRWDDLKTYHATAEAGSLKNAATALLAFLTPVIASSVLSHALTKKTGKVNFENIWQIFPRTSWSLPNFSASTPSAGYRPEIGSCPAAWTIDIEYVDWNGEASGFTTTSVNMCEFEGVRRVQALPVFPISFLGDVEKTKATFIARGRKFESLRGYKFMLCNGTKITLETEKPEQRPVSGKVCVDAYAYYRGCNIVKPKLRSLSVEETSEDEVEVPDPDLSDTPYEMDFSAAPVETSTAAKGPAERTEDLRALTDEQCLLSTPWMKGFDLKSKEWCELRVDDLKDMTWNDEAFEKLVLPEGEKDLAWAFVENKSLSKTDFDDFIPDKGRGLIILMFGPPGVGKTFTAEAVAERSRVPLYLMSAGDLGTQPSDVEKALERALELCRMWNAMLLLDEADVFLGTRTNESLARNELVSIFLTKLEYYQGILFLTTNRISSIDHAFQSRVDLFLPYHDLTNAARRQVWENFIDRAGRDKFDINEESLEKLSHLNLNGREIKNLIKSAQLLSLKSGGKVPMDRLYMLADKRVQALNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBK0</accession>
    <name>A0ABR1WBK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666993.1">
        <property type="nucleotide sequence ID" value="XM_066811651.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044711"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046184490" description="Secreted protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="22858" checksum="E3D09FDA953A49E0" modified="2025-10-08" version="1">MWHSVHLQNHPVHLRKLLCILGVLISPVAPSTVVIHVRGEPQNGLGLKLGFPCPEDGFEVLELHSACIQLDDGRRRNCRDPVDDGAAHLRVARADVRRLDAAPTSQWLRHLSREMLAVAGAHVAMHEPLLCDDELPHASLPRRATGQSGLELFAVGDEDDRLQGALGLVSPGPADETAAEEVLGALLHAVLVPGVVSGRPVHVGEDDLPELGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBU5</accession>
    <name>A0ABR1WBU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carnitine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007804</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667461.1">
        <property type="nucleotide sequence ID" value="XM_066812119.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045179"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF103">
        <property type="entry name" value="CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="6">
        <location>
            <begin position="35"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8079986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="610" mass="68548" checksum="5B3DA3A9072405DA" modified="2025-10-08" version="1">MAPAAKRSNSSLPAGYAEDKSKGPMLRFQDSLPRLPVPTLEETSARYLKSLNPLLSSDELASSKTAVEEFVKPGGVGRKLQEKLVAKREDPNVRNWIYEWWNEAAYLAYRDPVVPYVSYFYSHRDDRRRRNPAKRAAAITTAALEFKKQVDSGTLEPEYMKKLPICMDSYKWMFNASRVAAKPADYPIKYDANTHKHIIAIRKNQIFKISQEVDGQQLNTSELEAQFARVYELATRQPAVGALTSENRDIWTDAREILLNASTKNKAALEAVESASFVVCLDDAAPVTLEERAHAYWHGDGKNRWYDKPLQFIVNDNGTSGFMGEHSMMDGTPTHRLNDYVNDVIFNNKLDFSNPSVRSNLPEPTAVNFEVTKEVQAEIERAEKDFATVIGSHELAVQAYQGYGKGLIKKFKCSPDAYVQMVIQLAYHKMYGKNRPTYESAATRRFQLGRTETCRSVSEDSVAFCASMADASAEDKTRIDLFRKAVNSHIEYISAASDGKGVDRHLFGLKKLLEPGEEVPAIYKDPAYGYSSSWYLSTSQLSSEFFNGYGWSQVIDGGFGIAYMINENSINFNIVSKGLGSQKMSYYLNEAAGDIRDLMTQTLEAPKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBU7</accession>
    <name>A0ABR1WBU7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668458.1">
        <property type="nucleotide sequence ID" value="XM_066813116.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046176"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="245" mass="28072" checksum="65344F2F5BD1685D" modified="2025-10-08" version="1">MDPQAYRRLLEEIHALREEKKELQLGQLALQRRLERQGSSAQQLRGQLADERQINEQLRDQLAKQGTAQKELQEKLNDQEAVNTALQMQLDDQQSSNFDLQMQLIDQDVFNKDLKTRLETAKGRMSEAVERAEDITLRYHAALAYTREAVTRANVAVRRANAEMARTDEAEVQNEVLAEENHSLYNDLMDAEDEISIVGATAEAAYLEADRLFAENIRLRATQAGVFRRVRNDTHEMASSDEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBW6</accession>
    <name>A0ABR1WBW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-alkyl-2-acetylglycerophosphocholine esterase</fullName>
            <ecNumber evidence="1">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008817</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.47" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668474.1">
        <property type="nucleotide sequence ID" value="XM_066813132.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046192"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF14">
        <property type="entry name" value="PAF ACETYLHYDROLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045790634" description="1-alkyl-2-acetylglycerophosphocholine esterase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="399" mass="43663" checksum="A9BD6CA805863683" modified="2025-10-08" version="1">MRTIQLSTAVVALVCYQAVSSSVVPPPTGPYHVGFQKHVVPVLNEADPFWLNNISTSFLVTVYYPTNQEPEPHDWTRPYLDPATAALYEVRYNLSAGSLSALPSPGLVPEAKPLGRHHHSTLFFSPGGGGPPTEVYTLLLSDLASHGYAVLALDHAHEQPFVRYPNGTGIYGLPILYGFDEPTVLAIQSTRVNDSLALLDYLPALEAKTGLGLSQTHIGIFGHSLGGSSAAATLLAEQQRRRSDESKRTVPSSFRAGMNIDGTFFGPLADVRQPFLMLGAEAHGTSPDPADSDATWPAFASLQKTAPYWRWINIRGALHHDFSDIGYWKQVVPAIRDGDSQLGSIGGDRLVEVWRAYVRSWFDVALLGRGTDEERALFEEGVDAEWPEKIWVGGKEPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBZ4</accession>
    <name>A0ABR1WBZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668521.1">
        <property type="nucleotide sequence ID" value="XM_066813179.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046239"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="37100" checksum="5AC6520FB3E94CB4" modified="2025-10-08" version="1">MVQHPKADTSVGTTQAQLYKAGSRGYVGPAQERLRSAASFAVVLEAMNQGVGPYAGQSGNPPVPYTQYGTLPIWQQQYQGSDDAQAGPSGWEHAESDPDNEDQGETDPEAAGEGDASDDGEEGEAIPEEDEPGNREGPAAGPGPAAAAAAGGSKKEEDPEAAQYLDRYRAKGARGKLRKLCDACRDAGNESCHFTILTRRCHECGKANVRHCTFKAYEKAVALQAKRSKARQRAREIAHTQKRNMEAAKARAERERDKPDTEHERKLKARRDRRHEKEAALQAVGQETPTQKSNRERQEKFSGLSPAAQKEVRAKNVDGVRKHLHRVKERNEASGSGQGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCF1</accession>
    <name>A0ABR1WCF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668651.1">
        <property type="nucleotide sequence ID" value="XM_066813309.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046369"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8081176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="205" mass="23450" checksum="DA814AF37859D9DA" modified="2025-10-08" version="1">MQAIQGAVEILELKQPYLRPRALIRLASFLRTDLDEEDLAPATPPPIVGDNMPNVIGNEHLFWGARGLHLLEERPNLPESVIQETIARLKHPTVWDYVAGILSAYPVMSDERFDRLLREIDDESFKRLYRTWATDDREEIEWQAAANAEGVSVIRFPGGSRKVHLDSRMKRVIREWWEERGLPPHGLPHGTRLLGGRSFAMSVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCJ1</accession>
    <name>A0ABR1WCJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ZEB2-regulated ABC transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_008965</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668622.1">
        <property type="nucleotide sequence ID" value="XM_066813280.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046340"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="509"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="544"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="621"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="654"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="765"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1263"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1309"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1344"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1460"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="144"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="856"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="809"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="830"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8081147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1493" mass="166983" checksum="AC313C35B207E71B" modified="2025-10-08" version="1">MASEQPPDGKQENFGVQSPKDLNEQPSAATLCGPDIVNDEGSEHFRQEAERRHSLVQDLARQYTRNSQFINLVSDFKQATTDPNSEFNPNGAHFNARAWSQSVAEHANAHGTRFRKTGLCFQNLNVFGYGNETDFQKDVGNVVLELPSLARGLLSKAHRQRRIDILNSFDGILNPSEMLVVLGPPGAGCSTFLKTLAGEMSGLYADPDAYFNYQGLTAEELHAQHRGDAIYTAEIDVHFPMLSVGDTLTFAARARAPQSLPGEIRGEYADHYRDVVMAMYGISHTVNTRVGDQYVRGVSGGERKRVTIAEATLANAPLQCWDNSTRGLDSANAIEFCRTLKLQSELFGRSCAVSIYQAPQTAYDLFDKALVIYDGHQIFYGPADKAKEYFINLGFECPSRQTTPDFLTSMTAPSERIVRPGWESRVPRTPEDFAAAWKRSREHAELQQQIQAYKEAHPFGGDDARDFRALKKTDQNRRQRLESPYLMSYPQQVRLCLWRGWRRLVGDPWLTVFQLVANSAMSLIISSLFYNLQETTASFYSRSAVLFVAILMNAFSSALEILTQYAQRPIVEKHVRYAFTHASAEAFSSILVDMPYKITNSITYNLILYFMTNLNREPGNYFFFWLTVFLMVLAMSGTFRAIASMSRTLSQAMVPAAILILALVIFTGFVIPVDYMLGWCRWINYLDPVAYGFEALMINEYHGREFACASLVPNPAVPGYENVTIAGGFSACNAVGAVPGRATVNGDAYINIAYKYFNSHKWRNIGILIGFALFNHLVHLVATEYISEKKSKGEVLVFRRGHNAARHAFTGKKDSEASLSGPVPVVEKNPQATNSPNDGSSSDGTAGVIQASTSVFQWKDVCYDIKIKGEPRRILDHVDGWVKPGTLTALMGVSGAGKTTLLDCLADRISMGVITGEMLVDGMQRDKSFQRKTGYVQQQDLHLETSTVREALEFSALLRQPAATPRSEKLAYVNEVIKMLDMEEYADAVIDHRRRTRRQAPLLLFVDEPTSGLDSQTSWAILDLLEKLSKAGQSVLCTIHQPSAMLFQRFDRLLFLAKGGRTVYFGEIGDNSETLTGYFQRQGADPCPAEANPAEWMLEVIGAAPGSSTEIDWHQAWRESPEYKEVHDELQRLKADGVGEGGREKRRNSMATQDGRATFQEFATPLWDQLLVVTRRVFEQYWRTPSYIYSKFALCISVALFVGKPSLPKRPLSIQGLQNQMFAIFNIYTIFGQLVQQQMPHFVTQRKLYEVRERPSKTYSWKVFMLSQVLTEIPWNSLASVFMWALTYYPVGLYRNAEAAGQTHERGVLMWLLFWQFLVFTCTFAHACIALADTAESGGNLAQMLFMMCILFCGILAGPNTLPGFWIFMYRVSPFTYFASAMLSTGLANTNVTCSAAELVKFDPPAGSTCGAYLDGYVEAVGGYVVDKGAASACQYCPMATTNAFLAQLNSSYDTRWRDFGIGMVYIVVNIVASLFLYWLVRMPKGKKEKKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDS3</accession>
    <name>A0ABR1WDS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008147</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667804.1">
        <property type="nucleotide sequence ID" value="XM_066812462.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045522"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053007">
        <property type="entry name" value="CYP450_monoxygenase_sec-met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="452" mass="50375" checksum="AC0E0F15E02CE58C" modified="2025-10-08" version="1">MPFQRIYVVNSPSLIPELEKQWRAVSFAAIAADADHVVGMSKEAQEIMHRDLMSEHSFSVSWPIFTAPAIAPGKDLDMTSRRFVETLSAQLDPMRAQGCPVKVGLYGMLRKLMEISGTEAIWGRQNPYRDSAIADAWRTFENGFLFFSMFPFATTLFPKFIQARELVAAAMMEYVRNRGFETASGLVRKRFEHHSKLFGLGTEDIARGEIGNTFAVLGNTAPCAWWVIFHLVSDARVLSEVREELLAAVHEDESGCHLDIASLRERCPVLLSTFQETLRYRAVNPGPRVILEDVALNNGILLKKGSMLMIPATVHHTDTTAWGEDAGRFDHLRFSRTPTAMGQNKFNRVAFRAFGGGHVLCPGRHLASNEIMALAALIILQFDVVPDGESGPSLRLRTHPQLDSPIPDKDIQVELRPRGPNKKWTFTFSGADKAIDFVSEDAMADGETARQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDX1</accession>
    <name>A0ABR1WDX1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008192</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667849.1">
        <property type="nucleotide sequence ID" value="XM_066812507.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045567"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="112"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="327"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="HTH CENPB-type" evidence="9">
        <location>
            <begin position="701"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="114"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="70"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="172"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="270"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="775"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="901"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="70"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="270"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="302"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="775"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="905"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1087" mass="122251" checksum="F9D75458DA7227F7" modified="2025-10-08" version="1">MPTIDELQEMDFINWDAAGAATGLNLDEQPPQGAFDPNQGTNMDLVLGDVDGDDWSFWALEHFDSTHLAQQTTASPPRSLRCSCQSLPRPNMPENNMSVASEEQHPAAPLPSLPSKPGARFSRESVKILKNWISTHSRHPYPTEEEKETLQRITGLNKTQITNWLANARRRGKIQPTRSTSPHVGRGYATAMDIPRRSGTPGLFENMNPLQRWANSPPENEPASVTDIARAITTSSTDMSSSSSLNSPYVSGYSDDGSGRSIANLSSASSLSKSQSSGGSFASSFSHHSRGSVGSLPSFARTRGRRRRRRIPQRRSQENLGEKPKTFQCTFCTETFRTKHDWQRHEKSLHLSLERWVCSPEGARAINSGSGVMSCVFCGEANPTDSHLESHNFSGCMERSLEERTFYRKDHLRQHLKLVHGVTFTSWSMDNWRVTTPEIRSRCGFCGVVMDSWTARTDHLAEHFKTGYTMADWKGDWGFEDPVMNLVENSIPPYMIDHERNSPFPYQASQSPSSTPTNAYDLLKFELKDWIASFPDDQSHPLTDEKIQMEACRIVFAGDSVSKGTGPAHSWLRDLVMAKPETSKAAMFRPRGPAEGCLSKVMITGKRDIFENCDLEAELQKFVIARRLLGLTAMDKELQEEACMIIGRMEEKSIDPSEAVANWFIRLIHNDAQWLTDFRRRAHLPRSEDVNDNPQRSHDPKSIDSTILNYSRLDNELGEFLRSQRSLGLEPSDADLQSEARIIIYEQDDDWNQTAADDSKWLEDFRARHAGGINTSTAMDTSIPSNSQLQKPPSPLSGFPATLTSTPDRQSPRPGNRSRPGVYMYYLNEANCFRRLSKELGRFVASAMSENNPNQHIPTDEELQYQARWIEYDDDDKWNQTPADNPEWLRQFKQDVGILPRDSQPEQLDTTSWAPSVGTTDPSAHRPSIEFDAMLQTPNMSTPFAVDDFAAASQAEQLDPMRHETPTRTFGNPQLASGLTAYVRRELQKNRIFPSDADLQARARDIMSMQKTPADNPVLLGKFKASLQGHCPWQQRPSPDEEFQFTMDDMDTSFTDQVFDSIVQDLNASSASSRSPSCITPNTAMHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEN8</accession>
    <name>A0ABR1WEN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphotransferase</fullName>
            <ecNumber evidence="6">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008432</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668089.1">
        <property type="nucleotide sequence ID" value="XM_066812747.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045807"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF29">
        <property type="entry name" value="PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="7">
        <location>
            <begin position="85"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="8">
        <location>
            <begin position="255"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="544" mass="59294" checksum="D7360C66DBDE2101" modified="2025-10-08" version="1">MEPDFEDYLRPLDFNAETAHQLARELCCTFKQLAAESSVQFLATPVSESILRPPKGSEMGSSIFVFPYFLFRCKNSHADPRYISGGTNLRVGFVELLGKEDSTSQPKPGLQNGNGHPVRLRRQLEKSWPILDHLKNEHPDELFSWIGKCIAEVIADGCQSFGLPRDVTLPLGVTFSFPMVQHTLSQAELMSMGKGFAITSKADLGSHLLKGYENWRGSERELPLIRIVAIANDAVSTLVSFVYQSQESQSRKAAMGLICGTGSNATIPLGQSMLHPSKLPKVEILNGHNPDEQRIAVNTEWSINGTAPALRSLGLISKWDEQLDAAGEVPGFQPLEYMTAGRYLGELGRLILLDYLNNQGFAGEALPTKLQQRFGLTTTFLSHFKPPNPSALLEKLEVEFPVTDTNSGFAWTEDMAIKIYKIAKAIEVRAAGIVAAATVGLLACAGDIPLRESLEHESTEQNHPGANGSAATLKDLVVGYTGGCIEHFQDYLMDCQGSLDDILRKEFGSEPPFRVTLSPCHDGGITGAGVLCGAAQAQYQLTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFG1</accession>
    <name>A0ABR1WFG1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="10">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_009033</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="10"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668690.1">
        <property type="nucleotide sequence ID" value="XM_066813348.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046408"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17949">
        <property type="entry name" value="DEADc_DDX31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="181"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="408"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="19"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="672"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8081215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="722" mass="78678" checksum="42C6C0753CA0099F" modified="2025-10-08" version="1">MADDGMLLNFDLGDSSLKSEVKFTGGRWRDRVRAQRTAKGKPSKSWNGVNGAPLERARQFGKDTGGGGDDDDDADADDADRPAKRQRTAADRTHTGHRTPYVKAGLPPGQVTSRLFTSNPTATTVFENAQPEAEPAQPSNAPLTAEAETFHALGLSKRIAHHLSTKLEMKAPTSIQKNTIPQLVSSDSDAFLQAETGSGKTLSYLLPIVQRIMALSHDEDGTSTGTKIHRNSGLFAMILAPTRELCKQIATVLEKLLRCAPWIVSTTVIGGESKKSEKARLRKGVNILIATPGRLTDHLDHTKVLDVGTVRWLVLDEGDRLMEMGFEDELKMIVSKIREEGLKTKNEDGVLLDRLPQRRVTVLCSATMKMTAQRLGEISLQDAVHVTASKSDPESAETNDAVFSAPAQLKQTYIITAAKPRLITLLALLKSTFARKGSVMKAIIFISCADSTAGTVAEAAYITSPANHKIALFKLHGSLPQPIRTATLKAFHEESDPCVLITTDIASRGLDVPTVDLVIEYDPAFAVDDHVHRIGRTARAGRPGKAVLFLQPGSEEGYLAHLQAAMTGQSSESIIQKSFITPIMLPKKSGTDSEAPVLQSDKSAMKRAEALQLHIEQRLLDEKNGAKLLDAARQGFRSYIRAYATHVKDERKYFDITQLHLGHTAKSFGLREAPGGIGGGPTRRVVKGPCSSGREEEEEWRWRQERGCTQGARGAGRQRCGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM89</accession>
    <name>A0ABR1WM89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005927</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression. CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with creB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat creC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669165.1">
        <property type="nucleotide sequence ID" value="XM_066810242.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043302"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051362">
        <property type="entry name" value="WD_repeat_creC_regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14107:SF16">
        <property type="entry name" value="AT02583P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14107">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="417"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="115"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="512"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="595"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="614" mass="67487" checksum="1A835A6A0EC458A1" modified="2025-10-08" version="1">MFVLPPPPRYPTQAAYNAAVAAGQATPMIETNNILTTPEEQFLVGEGTYVLKEDLHLATPPPHPSEAPVINPNPLATTPQPATAGTKVSLLSFAVRPPPPAFYRLTSATALSASIAEHPNESRESQNAKLSSDGEGQSASFSDGGPSTSVTAVSAPAFGEGNASLAPEKTKDANKRRKPKNNMTKSNSSFISRVIINESFTKKLADRPGDGLFAFANINRAFQWLDLSSPNKADYLTKILFTKAHCLCHAVNKVTKGPGHLDLIMGFSTGEIIWWEPISQRYTRLNKNGIINKTPVSEIQWIPGSENHFMAAHMDGSLIVYDKEKEDAAFNPQEEEETVDGEGETSARVVDHLSRIQILKSVHSKNQKTNPVAIWKLSNQRINAFAFSPDNRHLAVVSEDGTMRIIDYLKELLLNIFNAYFGGLSCVCWSPDGKYVVTGGQDDLISIWCPSERSLIARCRGHQSWVTSVAFDPWRCDERNYRFGSVGEDCRLCLWDFNVGMLHRPKAASVRHRGSISSRTTNLQRAETQGTTASRIRSNSGYSGFEGAEDDIQSISVPVEPRSMTATIPPVLTKKADKDPLCWLEFTDESIMTSSKTGHLRTWKRPSDNPGPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMD8</accession>
    <name>A0ABR1WMD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005976</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669214.1">
        <property type="nucleotide sequence ID" value="XM_066810291.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043351"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF2">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="789"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="647"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="1128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1160" mass="130786" checksum="F883568FE51EB8C1" modified="2025-10-08" version="1">MFSNFTGQSKRPRNVNLSGQRNNPWATPGSAWGSSTGASKTVAQAQAEREKRQRERDELAASRKLQRVWRGHHARRSTKNEHRRQWDQLYHNTESVDVPMSDGDAVADPERAREALPLLLSLFEPSLSHDQRRLDQFLLDASSEAWKPQSHQYKRLASLLVTALEKRPLNFSQRPFALLVRLVVEEPRSIAAIEDRYYKLLASYCESAANDIDHSGQELLAEAVTAPLDHRKTKYPEAYTTFAYSFLTCSNITFLQKKPEAIARRLDLETLSRTIISGSRAEVSGQRSKEQLLWLLAHFIALNRALSTAQGSVYLEALYQQLCPLIDDIRIRSAPQPVEDEADSSDDEDESAIRKANPLPAYVLHQLEFLVNENGISELLNRFTSTASSSVRLSEDASILAGYTLLLLRCFPAQRDDMRMRLFQGDIRTQGPEGSVYLPSVKFLWLAVSKTEVFTTISQPKIKILSSTIVSLLRSDPARDQEWRIVLLFLELYNFLLRVTDDDDFLVDERNVIVNQSPAVKRIRASGLSISELELLVTFLKNLSFTLYHNLKDVMPRDRSRPALGALLGVSPATSTRNIPEQADAPSFAGILGLDPLSLRGCATTTMQSLYERDSRRSFLPSGFWLMTSKFDMEGFISAVVLEEQQSQNAEDDEDMSDSDINPVDNHTSAGQRLSRAAQIERQRQLQRVHKEQLLSQLGPKLEILRNMPFAIPFDVRVKIFRQFVDIDKIKRRNGLVDPDQWRLGLLNGSFGGPHQTGRDVLGRHTARIKRGQLFSDAYDQFYALGDGLKEPIQITFVDQFDQPEAGIDGGGVTKEFLTSVSSEAFTPGDEGPRLFVTNSQNLLHPNPAAFDELFEDLTSAGVPKSDWGPRITELTQQYEFLGRIVGKCMYEGILVDIAFAPFFLLRWPTAGQSTSDFRSSLNDLRDLDPDLYKGLMSLKNYSGDVSDLSLDFTITDQVTNPRTGQSRNIVRLLRKDGDKTIVTNTDRVLYISYVAHHRLVAQSLRQTKAFLRGLSTIINPSWLSMFNQSELQRLVGGDSTEIDIVDLRNNTQYSGVYSIGDDGEEHETVKMFWDVMKELADTERRALLKYVTSTPRAPLLGFSQLSPRFSIRDGGDDETRLPSTSTCVNLLKLPRYKDAKTLKKKLLYAIQSGAGFDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WND4</accession>
    <name>A0ABR1WND4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lecithin: cholesterol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005803</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669041.1">
        <property type="nucleotide sequence ID" value="XM_066810118.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043178"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="639" mass="71043" checksum="22E8A417F10BE492" modified="2025-10-08" version="1">MASELRRRVLNPDTASDESAPASPREDSPVRPGDKVKVIHHIQKAKTQKRKSTMIFLIGSLCGLIAAGFLAQSNDLIAFPELGELSMDSFLDVLPAGFSKEMKDLMNGERKYIESYDAFSVGLKAKAAGLHAHHPIIMVPGVISSGLESWGTANSSRPYFRKRLWGSWTMMRALVMDKESWKKHIMLDKVTGLDPPGIKLRAAQGFDATDFFITGYWIWNKIFENLASLGYDPTNSFTAAYDWRLSYTNLETRDQYFSRLKLHIEMAHKFTGKKAVLASHSMGGQVVYYFFNWVASAKGGNGGDSWVDDHVEAWINISGCMLGAAKDVPVLLSGEMRDTAQLSALAVSALDKFLSKDERAELFRAMPGISSMLPMGGDRVWGNLTWAPDDRPGQVHSYGAAMNFRMGMNWSTPTANFTMEAARAYLMNSTEEWYRNHLKGSYSDGIADTAAEVEANMDDPVKWINPLETRLPLAPNLKVYCFYGVGIPTERAYYYRTSDASMFTNLSMTIDTAMTVDEIDHGVIMGEGDGTVNLLSSAYMCNRGWKMKRYNPAGVKLTVYEMPHEPERFSPRGGPNTAEHVDILGRTSLNDFVLRVAAGKGDTIQSNVVSNILEYAPKVKIYEEDSEVADEHPVTSTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNH8</accession>
    <name>A0ABR1WNH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669101.1">
        <property type="nucleotide sequence ID" value="XM_066810178.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043238"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.390">
        <property type="entry name" value="Hemimethylated DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011722">
        <property type="entry name" value="Hemimethylated_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036623">
        <property type="entry name" value="Hemimethylated_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31350:SF27">
        <property type="entry name" value="HEMIMETHYLATED DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31350">
        <property type="entry name" value="SI:DKEY-261L7.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08755">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00992">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141255">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="630" mass="72759" checksum="F738E61AF8E48B0D" modified="2025-10-08" version="1">MASFDALPDELITQILHYTSPEETLLQISPVSKRFACVAQTPLLWRYYCDTTFKYWQADHAFHAKRRNKRLQIDWRGLCTLRLIRNRKISRLLDGIVATRLERLQRIEEICQYGYDAKDYLLSQCNIDDDAPDVLARRYYACTVLDSIHRGLAIAEWAKYQKHAARHAGRDARPSDKINCGMRLERALGAFDMFVLHDNDGDLDEISVILDQLASRFRRETPDVDDMTIREKSMALSRWLHASNLTAAQGDEGVAKYLRTCLIGRALQDNRHPSMPIISAAIFSSIAERLNVEAYCCLLPTQVYIVVLSPQGVSLDGRPIPEEEEQQQKMFIDAYGSDGEVSVDALRVFLNRLGAHSGHDNLLRPTSTDLIVMRTAQNIRSSFTSFRTLERPVADLVPLIELRHGDWARNLQPALYSMIWASIMMVPVLPDNEDMRRDWQQDVRDLLQYFYEYFPEDSWLVEKYVCPMYDTFAAPGRRQNNWELPSRRVRDQIREIRRVDSTEKAPWKRSTLDNPGKVKYRIGQVFKHKRYDYHGIIIGWTVNGAGFDDSSSRVESRVAQPFYRCMVCTDGSDHHVIAEDNMEVLDLKGGVQGLPREIRDLVPMAGKFFKRWDSESGIFVSNLREMFPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPD6</accession>
    <name>A0ABR1WPD6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005592</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668830.1">
        <property type="nucleotide sequence ID" value="XM_066809907.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042967"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01830">
        <property type="entry name" value="XynE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053140">
        <property type="entry name" value="GDSL_Rv0518-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784">
        <property type="entry name" value="GDSL-LIKE LIPASE/ACYLHYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784:SF2">
        <property type="entry name" value="GDSL-LIKE LIPASE_ACYLHYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047167948" description="SGNH hydrolase-type esterase domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="3">
        <location>
            <begin position="295"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="501" mass="52469" checksum="601B260CFBAFD66E" modified="2025-10-08" version="1">MSPPGNAFILAELLLSSSLANPAQEPSSLSLRLGYSISPDPFCRAPLVWLAVHANCHISCPVSVYLPNGFLVLALAFLKGSALVSFKMLHSIFHIPRSLGVCVVALLALPSLVTTLALDPNYLQARQDDDAHWVASWTSMPQLVEQNNLPPASFRGGGAVFKDATLRQTLHLSIGAERFRFQISNTFGGSALPVTAASVALSAGNKVGVSGIETSTLLGLTFNGSESVSVPRGQVIYSDPVDIKAAAQSMVTLSLYTQAGQSGSSITGHPGSRTTSWMQQAVDAWVPTASSALVILGDSITDGRGSTDDANNRWPDLLLAKMQASNLTTIGVNNQAAGGNAVLAGGLGPPLLQRYKRDLLAAAGVRYCLLFEGVNDIGGASPDAGTQQRVGDQLIAAFRQVAADAHVAGLRGVFAATITPFGGNGQSYSNPAREATRQRVNKWILGGGDGSFNATVDFAKFVANSGNPANLATQYDSGDHLHLNPAGYQAIADEFPLDIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRX1</accession>
    <name>A0ABR1WRX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670135.1">
        <property type="nucleotide sequence ID" value="XM_066811212.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044272"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="25614" checksum="51378D377AAFE9CD" modified="2025-10-08" version="1">MNDTTPTTTAAQPNEQPKAINMDLVALRLGDKAFCVSRKGLRWSRYIREILNRADEQVLGAPGDLPWGDRVAPETMEWFLKLLSDLYDNSHDIRSVTIYGPEENRLECLAALPRLQELAELLGCADIPVLVRRTGVKIIRQIHVPQDTDADLKQSVRLFDAAYRAWSDTLVKQWIFMKFCKVVNDIPHAISLEPAISDEFREKALAYHQKSSVEHNVDVTDAIFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX57</accession>
    <name>A0ABR1WX57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670634.1">
        <property type="nucleotide sequence ID" value="XM_066807016.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040076"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="77"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="301" mass="34525" checksum="DF27800FC3674EE1" modified="2025-10-08" version="1">MLLKKSPVVLCSSSNLPTFIWPNLSTTSSCNPLRPVQSSSKPPSLRRQSCQLSRAPSRRRYATVSDTFPKRSETSVSHHDWPSVAHPTPYQIFDQKRDAPYSKARFYTLVKIYHPDRHIQTGKADSLSHAVRLERYRLVVAANQILSDPTKKRAYDLYGAGWGSKLSMDNSAYRHAEKSWRNEPGNPSMNATWEDWERWYGERDGEKAKQQTVFMSNEMFVVVLCAFVLVGSMGQARRANKGSMSLVEMHDQKHEAISHDIQMRKTEQTGLSRHERVESFLRQREGWNIPVHQPPPATQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXA5</accession>
    <name>A0ABR1WXA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670688.1">
        <property type="nucleotide sequence ID" value="XM_066807070.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040130"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03386">
        <property type="entry name" value="PAP2_Aur1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052185">
        <property type="entry name" value="IPC_Synthase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310:SF11">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE CATALYTIC SUBUNIT AUR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="192"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="374"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8087794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="47807" checksum="E027905DCF43C446" modified="2025-10-08" version="1">MQSPSKLHFKWPVPLDLAALNPISSIRQGRKRSNSKGKARTPGTESVAALQTSFSVSQSLRALRRHRWSWFDLQHVFLACLCSFSLFIIGVHAPLIKLAAALGYCLLLLMPATRQFFLPSWPIWTYLLYFFSSRVLPALENVLYGANLSNILSAHTHPVLDLFAWIPYGIGHFANPLICSILIFLFAAPKTLPVFAKSFGWLSIFGVTMALVFPCTPPWYENKYGLAPAHYGMPGSPAGLARVDALFGVDMYTTSFTTAPVPFGAFPSLHAADATLEALFMSHCFPKFRPFFIFYVTWLWWATMYLSHHYAVDLVGGSLAAAAIFFTARTRWLPHQQLEKAHRWEYDFVEVGEMKKAADEEYGYGLGLLERRGTGDSDEWSLSSGSAYSSTVIGSDSGPASPTEDRRSGESSFSRTTPGSPVSQLNGVSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXD1</accession>
    <name>A0ABR1WXD1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670646.1">
        <property type="nucleotide sequence ID" value="XM_066807028.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040088"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="240"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="276" mass="29736" checksum="ECD98A858A4FE02D" modified="2025-10-08" version="1">MPPAKVPTSEAYPLKAWRRQAKSKLAPPTPAAYEGKTVLLVGATGVILSDAARILSNLKIDTLIFGVRNVKKGEALADTLRPKHADVDFKTWEIDLFSFESVKKFAAMINDYGRIDAIVMGSAIMNEETKMTKDGWEETLQLVHLSAALLFALILPKLLAHAEDPTGLPPVVLSNVSSLSIRSTSPFLKLPATPAESYLGHLNRADATATERRNQYGYAKILQTCWLRDLCARLPPAPATGPSRSTRSTRASAPRPSASSASSPRSSCCGPAGPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXH8</accession>
    <name>A0ABR1WXH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670746.1">
        <property type="nucleotide sequence ID" value="XM_066807128.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040188"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047128457" evidence="1">
        <location>
            <begin position="18"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="203" mass="21223" checksum="4E7184464EB96EE4" modified="2025-10-08" version="1">MIYSTILLPALAGLASASPIGARQSKGPHMPKTVYGVDPTKPFYLTADTVGGEGAGAGKEYYLLPTFLDMQTSLMGLSATEPEYAPTPRANYTLTGNHYGTQLYAYASLPCTSPTGCPGSTRLQWSNVSPQSAEPATAAPAAMTFQQGVQQPSFGGLAFYGEYTGGDFAAGETNYLVGAGDSDFTKAWALCDYPQGNPRATTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXQ7</accession>
    <name>A0ABR1WXQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase II transcription factor SIII subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670833.1">
        <property type="nucleotide sequence ID" value="XM_066807215.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040275"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051870">
        <property type="entry name" value="Elongin-A_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010684">
        <property type="entry name" value="RNA_pol_II_trans_fac_SIII_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15141">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15141:SF76">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06881">
        <property type="entry name" value="Elongin_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="399" mass="44484" checksum="35734F060EF4D10B" modified="2025-10-08" version="1">MPQDNPDLQNDSPVDYTKITANQLKDIRDVGSAHYDLIRPILLRIDSAAQLRAIEEASPHLEEHDEEVWLRLIKREFPTLHEKENLKPSRPQLWHRVYAKYSRMDAKNKAEAAEKLRNAFAGIKAKKQANTSEIVTFDRRKLPQPPKDSRFKGDKKGSTGRRGGSNDTGELRFTSGTRTKVTTAQSLMRKVKREAKEIHSRNKIATPTNALRVNSGQIKHAPQGLVNEHRIKSQPSLKIQPPTLKRTFQDRDFGGKSLEEAEARLRNIKSGKQPTIVSDSDLDDDDDDVFGDGGGGGGLLDEDDLEAMFDDEPAKPEPSRQASRPLLPGKQRSGASSSVRRVETQIRQVPANNNVGSSPPSSPPRAQAASPPLKPSMPPRKRKVVDVFMKPKAKAHRPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXX2</accession>
    <name>A0ABR1WXX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the velvet family. VelB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670873.1">
        <property type="nucleotide sequence ID" value="XM_066807255.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040315"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF3">
        <property type="entry name" value="VELVET COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="8">
        <location>
            <begin position="113"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="423"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8087979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="442" mass="48607" checksum="811AD524F80977C8" modified="2025-10-08" version="1">MAGQAPPPGPGQYSHHPPPSHEPLQHSLPGPHHTYPQYYSGPPRPHPHLPPTRTEYVQGPMPSVLDRPQNGNGPIPEGPRISLRALSENTKSVNEDIQNLADHARPMSTEKEDSKWKYKLVCVQQPQRARMCGFGDKDRRPITPPPCIRLQVIDKTTGREVSSNDVEHQMFILSVDLWSWNGLKEVNVVKHSQNSPSISSTTQQSFRELQEGGPSYDTYPGMVRQGFAAPSQPPSSYGGEQYGHGYGQAPNLYANDGLSDGYAYQGHVGQYSVPSNVQSVPSQNGYAGRYPQDLTPQRANSLATPPNGMYTRNLIGSLVTSANRLLDPEDKFGIWFILQDLSVRTEGYFRLRFSFTSVGIPGTVGDASTSDPQRVNQGKAPVLAQCFSDPFQVYSAKKFPGVCESTYLSKCFATQGIKIPIRKEGADGKAKRGKGSDEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZW9</accession>
    <name>A0ABR1WZW9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003659</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671592.1">
        <property type="nucleotide sequence ID" value="XM_066807974.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041034"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF30">
        <property type="entry name" value="FAMILY DECARBOXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="217"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="355"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="421"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="441"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="460"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="486" mass="53130" checksum="2B3EB730EA074A37" modified="2025-10-08" version="1" fragment="single">GTGTGTGTRTSTQTPAPAPAPSRTAANMLTALAAESWAWYAITWLIVLVRIVSRRDLHGSFRKLQVDDGLMLLAMVTDTVLIAAMNIVANTSSNLIDPNDTAPLTSASIAEREYGSKMYDCPFRPLGSRRGTDADRDHMANESMSLNHVQPPHVSSLLPLTPLVAPSNEVCKQDEFKAEHCRKNRRCICFFGLRLDGDPLFRSLVSPIPPVLGRTPDNVQCSAATNHLITNAILNISSDLLIIMIPMPILLQAQLPIKKKAILCGVFALGTFTVSDQASIPSDSHRGAQSAYTNIREQQILAAVLNKFYSFHQPFGSEWTFWYIRESSTAIIVTNLPSTWTLCRRVFNLRSFHGKSSGARTSEAAKSRFTRSGYGNGRSHISSTERRIITRSESQEQIFHDDGLDVPIPLKIYQQHEVSIKTERVGDSEGGKPLEGHGNVSFASASTPTSAGFSSIDMSRSGEKKNSSESDSVRSTPGVTTVCTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X264</accession>
    <name>A0ABR1X264_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672408.1">
        <property type="nucleotide sequence ID" value="XM_066808790.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041850"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="67" mass="7600" checksum="9DCED69681B0BFFD" modified="2025-10-08" version="1">MPPSRPLPSQPDGAGGSRDKKQKDWKTIPPIHPIHRRKANKKQRQGRLVHLSGTREDMHIVVAYVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X271</accession>
    <name>A0ABR1X271_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672364.1">
        <property type="nucleotide sequence ID" value="XM_066808746.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041806"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="136" mass="14998" checksum="4B64AD470FA3D18C" modified="2025-10-08" version="1">MHSFFNSYKNLMAIAIETEYSWAAIEELKDRIANPDAYAAAAPAASSGDAGASAAAAETKKDDSEAEESDEDGGGFGDLLYVSPYLRKHIQKLTFFAAVKCFSMRTKSTIDMNLGIGRFYEILDKRKPAFHRIATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2F9</accession>
    <name>A0ABR1X2F9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transmembrane protein 16k</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004569</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672502.1">
        <property type="nucleotide sequence ID" value="XM_066808884.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041944"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF77">
        <property type="entry name" value="MEMBRANE STRESS RESPONSE PROTEIN (IST2), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="7">
        <location>
            <begin position="24"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="6">
        <location>
            <begin position="181"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="715" mass="82681" checksum="EF6F416E849E1F53" modified="2025-10-08" version="1">MFLFKRQGTFGDRDQTVLNRTFHDKYVVHYDFSDTDDETAKEEFKTLISDLEETGLQTEVRAGADHSLLVFVRVPQELLNDTMHKSRVKDWLWGITSERPEIGQRHQRDALPGTFEAEGVLSVYHLVNWQKEQGGAAITPGLGKWQNVKAIFPIHNGPANKELLKHLSQKMFLTKEDFDQIRNLFGAKVAFYFAYMQTYLLFLTFPAVTGVLAWAFLPKYSLVYAIVTLLRYWKIQQDDLSIRWHVRGVGSLKQNRPTYHYEKVVVDTAGRKKHLYPRWKSILRQMAQIPFFVLAVLVLGLTITAVYAMEILLSEAYQGPYQSYLEYVPTLVLAACLPYTRSFLEDFATTLADFENHRTQDYYEMSVTQKTFVLSFIVQYFPILLTAFVYVPLGGSLVPWMQNHLPAHVGEKLNVAPFEEDSNRLRNEVIALTVTGQVSDMFEEMVMPYMMHKLRGWYHQYKFWNSNHGAFQALAPDDPAEEAFLRSVRQQASLEPYNVQDDISEMVIQFGYLALFSPVWPLVSVGFFINNLIELRSDFLKICLEHQRPHPIRMDGIGPWINSLDSLTWMGSICTAAIVHMFGTQNHEGTTMFERWGGASWWSLPITIFISEHTFLLLRWIVRSVLQKVGSEQIRRERDERYALRKKYVEELEQTSKQRDALDVGLLERRKSVRMADPDLFWTKQAREGVSDVVGIKLIEALGRTRNGGLSTKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2Q4</accession>
    <name>A0ABR1X2Q4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b-c1 complex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004653</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the UQCRB/QCR7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672586.1">
        <property type="nucleotide sequence ID" value="XM_066808968.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042028"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1090.10">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003197">
        <property type="entry name" value="QCR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036544">
        <property type="entry name" value="QCR7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02271">
        <property type="entry name" value="UCR_14kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000022">
        <property type="entry name" value="Bc1_14K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81524">
        <property type="entry name" value="14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="125" mass="14652" checksum="7F58369AC7E2C4A6" modified="2025-10-08" version="1">MSAYPSLAPFVMKRPWLRNMLKPVANWYSNAAGYRQLGLRADDLILEEDEQVLKALKRLPPQEAYDRVYRLRRAVQCSVTAKILPKEQWTKPEEDTPYLKPLIEQLKAEEKEKEDLDSLTIIKNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X353</accession>
    <name>A0ABR1X353_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672709.1">
        <property type="nucleotide sequence ID" value="XM_066809091.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042151"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="98"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="380"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="541" mass="60930" checksum="DF4CADEB292815BA" modified="2025-10-08" version="1">MNGYAASKWTLSHEEKLLLIEERSMSDVESESGRMDLDQRFPAQQWLSTAKSYGKAFRISALTSVVIRSAIFLLPSFLHPSRNSRERLRGGDKLGPTAYLDGMRGLAALFVFFCHYFYTSFVIAEGWGHNDANYHFWKLPFVRLLFSGPSMVCIFFIISGYALSLKPLKQIRGRSFEGLLNTIASFIFRRGFRLFLPTAASTFMVVCLLQLGAYEGTRDFAYDSNYVRNVAEHHPILQDTFSEQFLHWAGEMFNFLHFWGWEKFGGSTGYDVHLWTIPVEYRCSMVLFLALIGLARLRTGARFACIAILMWFMLHNDRWEPLLFLVGTVLAELDIIRGAHSNAGPASSSAGSAPASLLPFEEKESSSSSRPCKCRKAQGLAYVLLSVPALYLMSEPDAGPDGVPGWETLGALIPEYFSDRYRFWQMVGGALFVFCVARAPLWQRVFTTGPVQYLGRLSFAIYLMHGPVTHTLGYRVQRWAWTSVTGADTEAAFRSGAILAAAINIPTVFWAADIFARAVDAPIVRFTRWLETRVSITAEQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3B6</accession>
    <name>A0ABR1X3B6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PXA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004825</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672758.1">
        <property type="nucleotide sequence ID" value="XM_066809140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042200"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF47">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 122 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="PXA" evidence="4">
        <location>
            <begin position="105"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="379"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="629"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="403"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="726"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="770"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="792"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="977" mass="107549" checksum="224B50BD6F4ACA4D" modified="2025-10-08" version="1">MTRIFTFLSTATPTTLGGVATGLAAATYLVLGQVGLVVIGAFSGIVVFAAWEAKHPEVSRAVRGEKGYDILDRLFETRSQLAKAQSDQNDDTDFQSLVRSFDDFEPETREALEELVNAVVRDYIDYWYNPIVPSDNSFPLSVRRVLTSFVLSVSNQLSRKRPADAFVDFLTHTCSIIIVFFSEMTSAYASVSAEHKSSASDTMYSYLASHTESPLANLLNTHQQAGKLKMVAEDLLSFLDRPTYDCDPARIFLREILASVVLEGTLQTCSKAEWINGWIVYLLESGDTDLSHAIDEAMQDQKAFSDIDGNFGNEEMERAMEEMKRLNEMIAQADKARDSTSSERERESETAGRLNDAIKENAKELDLDVDQEVIDSARRAVQQPLPIQGKTPTEPATEKSLSRESLPQSPTTPGTADLSSRNSSPSQKRAVEAHRRFTSFDQIVPPSQDDPEEESTNGSPPPLTLVNAIITIHDEPGTTKLRNKPTWEYLVQIEPAAVQHPGWMTMKTYAQFEVLHESIRRLATISGANAFLEAHATFPSWKVHTRSSLRGDIERYMRAACAEKALAESESMKKFLEKDQEIKQGLNRGFSFESMGKGMLGVIQNAPKGAFDGGKGLVGGVTGVLGNIGIGQRKSPNPAQAAREPPPVKTNGANPATRPLSLSALPKMEAVSPMRSRDSLDSQRSAVIATQPGKMPPMDRRPSAVADTEQEGLQPARAERWERKSLSAASSAMHSRSSSTAALRSPSEMSLSNMKLPPPPDQIADDYDSPNETRQSSDTQSRLNDAPLSPFTALSSPTRSFNSQHPEKSSQPSISVKRPRKEFSPLSEQETRVAVELLFAVINELYTLSSAWNIRRTLLTAAKSFLVRPGNPSLVSIQALIQDNVLDTNTSDSGIAAHLKKIRENSLPTEEERKAWPAELTTEEKEELRVKARKLFIQSSVPAALMGIMGQSATSEALGRLFDCLQIEEVSRGLFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3J6</accession>
    <name>A0ABR1X3J6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hyaluronan/mRNA-binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004944</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672877.1">
        <property type="nucleotide sequence ID" value="XM_066809259.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042319"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039764">
        <property type="entry name" value="HABP4/SERBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006861">
        <property type="entry name" value="HABP4_PAIRBP1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019084">
        <property type="entry name" value="STM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299:SF17">
        <property type="entry name" value="AT19571P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299">
        <property type="entry name" value="HYALURONIC ACID-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09598">
        <property type="entry name" value="Stm1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01233">
        <property type="entry name" value="HABP4_PAI-RBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hyaluronan/mRNA-binding protein" evidence="4">
        <location>
            <begin position="108"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="191"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="269"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="323" mass="34164" checksum="EDC1CD4A0EBC72BE" modified="2025-10-08" version="1">MSVASKNLFDLLGNDADGDSDTPSGPVKTVDKNTTRTTKRTVEPVAPAKPVTANTGARRGPGGNEGAFRDKNAGSSSNQRRGTDEATRGGPRGGRGARERGGRGGRYPRERDDRHTKSAVTGSEKQAAQSWGAQEGEAEAKDEQAGEAMAQSELKEATAEDAQNADVIPEEEDKSVSYTDYLAQLAEKKLALGGGPDIRKPNEGSKADKKWASAKALVKEETDFVSPTATKTKRERERKEKQVLDIDQRYVEPERTHGGRGGRGGARVEGGRGRGEGRGGRGRGEGRGGRGRGAGEFRGGRGGRDNTSSINTKDESAFPSLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3K6</accession>
    <name>A0ABR1X3K6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_004967</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>GTP + AH2 + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + L-methionine + A + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the MoaC family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672900.1">
        <property type="nucleotide sequence ID" value="XM_066809282.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042342"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21117">
        <property type="entry name" value="Twitch_MoaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="entry name" value="Molybdopterin cofactor biosynthesis C (MoaC) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040064">
        <property type="entry name" value="MoaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="MoaA_twitch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047594">
        <property type="entry name" value="MoaC_bact/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050105">
        <property type="entry name" value="MoCo_biosynth_MoaA/MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006870">
        <property type="entry name" value="PRK09364.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960:SF0">
        <property type="entry name" value="MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01383">
        <property type="entry name" value="cyclic_pyranopterin_phosphate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01386">
        <property type="entry name" value="main_SPASM_domain-containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01067">
        <property type="entry name" value="SPASM/twitch_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="Molybdenum cofactor biosynthesis protein C, MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="90"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="477"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8090006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="667" mass="73902" checksum="5641119CA546E4D2" modified="2025-10-08" version="1">MLKPAGRAACYYLPRLAARSASRRHIFQTRGIASTAVARAPSTVATTTDDVRHHAAPAAGAEVTPFPEGGSSRRDAIKAAKPFSDFLTDNYHRQHDYLRISLTERCNLRCVYCMPEEGVPLSPQRELLTTPEVVMLSSVFVSQGVNKIRLTGGEPTIRKDILPLMQQLGALRPYGLRELCLTTNGIALHRKLDGMVEAGLTGVNLSLDTLDPFQFQIMTRRKGFDAVMKSMDKVLELNRHGAGIKLKINCVVMRGVNDREILPFIEMTREKDIEIRFIEYMPFDGNKWNKNKMVSYSEMLDRIREKYPTVEKVKDHKNDTSKTWRIPGFAGRMGFITSMTHNFCGTCNRLRITSDGNLKVCLFGNAEVSLRDILRESNNGDPIEAEAYEAMKQIEMTRRQTILTEPAKPLGLAPNEQHLLDIIGMAVKRKKEKHAGIGELEHIKNRPMILIVPPSYLPMSQSTTSGLQQRLFSHSATRLNDRSSKPPKLTHVSGSGSAHMVSISDKSPTKRMAKAVCTVRFTNEVAVKLIQENQMKKGDVLGVARIAGIMASKRTPDLIPLCHPIAISKVSVDVFTQEEKTGKTQDRPGSTVEIEATVSCEGKTGVEMEALTAASTAALTVYDMCKAVDKGMVIEGLRVVYKEGGKSGTWVEGVSMQDHESVSDEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3P2</accession>
    <name>A0ABR1X3P2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672866.1">
        <property type="nucleotide sequence ID" value="XM_066809248.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042308"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="279" mass="29323" checksum="0E13E921FB020617" modified="2025-10-08" version="1">MAQTGTSDIPSPEGSKHHSATLPEVCPESGLLVIPPDSTLEVYRPQIQHASGLEVTSSCYEPATPPEKKLPWSRTHRIWIIAGAIVVAGGIIAGVVGGTVGSKSRYEGSTEALSSSLSLPVQTPSTTSVSSATSTPITSTSSSTSSARTTKTETVSTRIAAPSATPSNQVYVGELDDGTSIDFVANASANAACAWAVNPVREGHNPCDSVFRLPHGIDYIWNDCGGEVWITWRNPSNDNEINYQDLGNPKGCGDVPKTYKCGTETIHAKYICPDHPIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3Q1</accession>
    <name>A0ABR1X3Q1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672916.1">
        <property type="nucleotide sequence ID" value="XM_066809298.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042358"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="353"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="353"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="316"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="410"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="449"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8090022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="556" mass="60080" checksum="E4C7426142DCC51B" modified="2025-10-08" version="1">MTSTHLQQHQHRSVLHAAAGGSPRMHRPPPYHPAASSPFPATSSSALRPPNTRPRAPSPRRAPWCPLIAVDQLPAWIDIAGVPRELTVEQTMGLQNLGTVSVHPGETTEYYEVRLHQDVRFVKSSSSSQSALKRRESSKNNASSLIMDPDTASLNVHETDLLGSGSSSKHAHKKQNDLVTLVNGSSGRHSGNMNNLDDSTSSALNSSSEISYSSFSTEPATNHTRSKKTPTKKGKEKAPKTETAAANSSKGPNGNTTTTTTTIKPPIIPLNPRLPTPPPPPIPTNPYPLLRHVRGGSEPLPPNHHPASRLLSAIAPPLYSPTHPQQQQQTAPNPHSPYDPHNPNSKSSSQRHQRAIVHCRHWCHHGSCKYGPDCRYEHEMPRTHERLREVGLGDWPNWYKAAIQMAFDMRKKKKTSSSAHRSSKGGSMRPQESTASSLSYVDVMTAIMMGGEGGSGSTRRKGGSSHHHKARDSSNSMNEVASSSPSTVAHTNSSEKTVVVEERLGRLASIESGGSDGGSSDAEHGDPELGVQPTPVTRKQNVAENITAPVENLVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X488</accession>
    <name>A0ABR1X488_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HET-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005174</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673107.1">
        <property type="nucleotide sequence ID" value="XM_066809489.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042549"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF12">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="82"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="3">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="715"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8090213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="772" mass="87309" checksum="CF61EEF0F93F5A0C" modified="2025-10-08" version="1">MRNLESSMPKAQADGQAGSVPFPAACVIRLGCVAGYVFWEAALIQFFNFHCSLSEGAWGIMWLIDTRTLKLVFKTDPSEIDYAILSHTWEEEEVSFQEFQDMRRARRKKGFNKIEMTCRLARMKYSLKYAWVDTCCIDKSSSAELSEAINSMFRYYKLSFICFVYLCDLSSDTSPGPGPIPGPPPSFSQCRWLTRGWTLQELIAPCYLSFFDESWSLRGSKDDWADSLSSITSIPSGALSGWRQLDDYSVAARFSWAAKRQTTRKEDLAYCLLGIFGVYIPLLYGESENAFLRLQEEISRSTNDMSIFAWQAVPEDERRFSGMYAKYPAEFVHCASVTRMPSASRHDKEYSLTNKGLRFDHVLTTFAENADYIKPSKLSASGGLERVYNERIESLGVAFLDLECFNDDPDGSSTGENSPTLGVYLTKLQGEYVRTFPNLLSAKYIRVHVAVQMDEEQLIIYAIKALTEQQSNKLEKEFHKEIIARLDISGGVYQPAMIKQVEPQSAWDHQDKSFHLWEGKDTSEISCFWLLTIDQIPLGGTIYTMECLVVCIFSREPVFGTRKALWHVFVGREGEWKIGNRIFCKPIHQVFREQTALEQFQECLRQEHDSHHRARYWVAVALSDDKLLHPTGWRDLLVTTPDSEDLEEVLLLIHQARHRNDTCPCYAHNPAKDLDTQPTGSRVLQYSSAKGHHGQSGNDDGGEEGTQLLVYVGQGVEGDGKGAGKTDEYPRRKAKHDGDGRLLIGDPSGKLGGSRHSAVNAEHNSTFWVSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4M8</accession>
    <name>A0ABR1X4M8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysine methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
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            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_066809616.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042676"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
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        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046773339" evidence="1">
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            <begin position="17"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="135"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="459" mass="51651" checksum="7D59C594113FA9AE" modified="2025-10-08" version="1">MGPLHLALLFPALGLAKDPLSHLPDFGSCKSSSLLGSLWGNDAAACSPDGAVGLVVEDSNQTVAKLTPATWRFSKPCMENGKREFCIYSSPDFANGRGIMMLTTPQRAGEVERSRIFTQPEIYASMPNLNAETSDRWRIEAVPGKGMGLIATRDLQVGDHIMSTTPSVMIDYDVFYELESAQIHQMQGEGISYLPERHRNIFLNLSTHDGAEDYNSRVNKIILTNAFDIDNTGVVEKKEEGERESWYTVFPEISRMNHDCRPNADYYFDVETFTHNIHAVRPIMAGEEITVSYIENMCADQIDHHSPVQPRHERLQRLNTSWHFPCSCSLCTQNAHQTAASDARIAQIEELRAQFRDYEPGSQATPAMGELMVSLFQQERLWSSMYEAYTYAALEYNGAGEPWLASKYARLAIEHGLAAGGPKDSDVLAMQALVKDPWAHWSWMLRTKRRMNWVSNVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4T3</accession>
    <name>A0ABR1X4T3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673268.1">
        <property type="nucleotide sequence ID" value="XM_066809650.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042710"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="39999" checksum="A740ED3A99332A7E" modified="2025-10-08" version="1">MLSYEDYTVAIVCAIDFEMSAVRYMLDKEHESLPTKESDSNLYILGELSGHRVALAWLPGTQGKGAAAVVATNLTRTFPSIKWRFLVGIGGGVPHGEKHDIRLGDVVVGMPEGPYGGVVQYDLGKDLEDGGFTRKGYLAMPPSLLRNAVEKMRSDHYALGNQAEENIAAMLQRWPRLKRVYARPATETDVLFDAGYPHPWDRSTCLDCDESKMVARSPRDSEGPEIHYGLIASGDRVMRSAAKRGEEVRRVGSDILCFEMEAAGLMTEFSGLVIRGISDYADSHKNDYWQHYAAASAAACVKELLSRVHPEQQQEKQSDVSGFGRPSLGSVATPQPFVTTLSGQGVVNSGSGNFAVGRDFHYSNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4Y6</accession>
    <name>A0ABR1X4Y6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673303.1">
        <property type="nucleotide sequence ID" value="XM_066809685.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042745"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="95" mass="10485" checksum="F8C2EE46B09C8261" modified="2025-10-08" version="1">MDQGNTGGGSGGSSSSSSSAAPRMYSVFPNLIITHSGKYRIYVEATAMDYENNQTERTAFAYSHEIEVKRRSVAEVKVSEKKRALLDTLHNEGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7R8</accession>
    <name>A0ABR1X7R8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673427.1">
        <property type="nucleotide sequence ID" value="XM_066806131.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039191"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045516230" description="WSC domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="2">
        <location>
            <begin position="21"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="116" mass="11756" checksum="92D8E2CEAC65DC1F" modified="2025-10-08" version="1">MFKNQAILALAVLGSAALAQAEKPVGCFPSVKGFVDLGPSTFQSVGLCNDQCQAAGFPVFGLTNGTDCACGQVADIPAADTKVDDGLCDTPCPGYEENTNHIVLGGGNGVVSVYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7W9</accession>
    <name>A0ABR1X7W9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673491.1">
        <property type="nucleotide sequence ID" value="XM_066806195.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039255"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="73" mass="7825" checksum="1DB9F47BCF2E5405" modified="2025-10-08" version="1">MELPAHGPPAIQEMPATTCIAELADTSIAPYRREDEISIATSNDIEGSSARRKSLRDGGGGSSLHARKFSWDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8R8</accession>
    <name>A0ABR1X8R8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">White collar 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002175</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673786.1">
        <property type="nucleotide sequence ID" value="XM_066806490.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039550"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF7">
        <property type="entry name" value="GATA-FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="542"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="679"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="7">
        <location>
            <begin position="900"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="934"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="936"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="981"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="992"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1033"/>
            <end position="1042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1042" mass="114442" checksum="974324AA2080E60A" modified="2025-10-08" version="1">MDSFFGTQLSQEELQRRHAQQRNQRRARISPSLQHHMNMPNMSRDTMSIHQDTAMVGAESLDDIIQSNNQELQRRRSLPQSPYDRNNFPQPPDPRRVSMMDFANHDYRDYQLGGMPTTSTDGMGGGFPNMNHNMTMPGTTGSFSPPNLMVDDFSAISPDMMTSMIAFSNMNMEHMGGDPTAMNMFQSGMPTGFSQSSLGTVTPSYSMDMTSPNGQMETPHSAVGNSMIMNNGDTNMMDTSQQQFVAATQAPQPPPNLTLDTAMSNYQPNVSPQPPTQMHSQPPGQIQPIESASQSPSGNSILDMPQEETQPSMPPVPLIAPKEQKAIYSKSGFDMLKALWMVATRKNPQVNLGAVDMSCAFVVCDVTMNDCPIVYVSDNFQNLTGYSRHDIIGQNCRFLQSPDGKVQAGTKREFVDNRAVFNLKQKIAEGKEVQQSLINYRKGGKPFLNLLTMIPIPWDTSEIRYIIGFQIDLVECPDAIASSQGQGAMKVNYKHNDIGQYIWTPPASSQWEPEAGQTLGVDDVSTLLQQFNPKGAVSDWHRQSWDKMLLENADDVVHVLSLKGLFLYVSPSCKRVLEYDGPELVGSSISTICHPSDIVPVTRELKDTATGSTVNIVFRIRRKESGYTWFESHGALFVEAGKGRKCIILVGRKRPVFALQRRDLEANGGIGDSELWTKISTSGMFLFVSSNVRSLLDLQPENLVGTSIQDLMRKESRPEFGRAIEKARRGRIVTCKHEVQNRRGQVLQALTTMYPGDASEGQKPTFLLAQTKLLKASSRSIAPAASQINKANHIPPTDPRYISTLTSAHSPKAGNSGVKEAEDHGLVSAAGGGIPLGSQDKALASDDNIFDELKTTRCTSWQYELRQMEKVNRILAEELHGLLSNKKKRKRRKGVGNVIRDCANCHTRNTPEWRRGPSGQRDLCNSCGLRWAKQTGRVSPRNSSRGGNNDGASKKSTSPVHSSPLQREVSTGEISEHPSETDSMTTAQRSHSSSAGPGTSAGTTPTASKGPSKPPLSQPLLEGGAESGPMASIREEREASSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X998</accession>
    <name>A0ABR1X998_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease for cytosine/purines- uracil-thiamine-allantoin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002314</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673925.1">
        <property type="nucleotide sequence ID" value="XM_066806629.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039689"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF0">
        <property type="entry name" value="PURINE-URACIL PERMEASE NCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8091953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="586" mass="63053" checksum="5E6C5C5F9A523748" modified="2025-10-08" version="1">MATAVRRVKTAFSSKEEFKKALLAPDAPAEGAAYFNEDLLPTPPERRTWTALHFFSYYLTQTFSSGSYNLGATLVSIGLQWHHGMIAAAIGSLILSAIVVLNSRGATRYHVGFPVFARASAGVGGAKLFVVVRASVAIIYFATQTFYGGMITAVCLRAIFGAAWDRIPNTLPASAGISSKNLLAFFVYWIVQFPVMFLHPTLLRHLFVVKAVYTTVALFGVLGWAVHANGGSIGSFSYDKQIVLSGSALVWPMIQAINSVMGALCPILINQPDVARYAISFSQATWSQSTGILVSKLIVMFVSCATTSATTGILGKSYWNVWDLYDAILSEFWSPGARAGIFFAAFGMVLATIATNAGSNSLPVGADGSGLLPRYLTIVRGQVLCAVLAPLCVPWKIISSASTFLTFLGSYTVFLMPICGVMVVDYWTLHRGNLHVPSLYTKAAGSPYAYTNGWNLRAVAAWVAGVAFTVHGIAGSLDPGAVNQASKDMYKLGFLLSFFIGAGVFWVLSLIWPVPMYPADHTTADYDGDSKSFEYMAQSEGFFAGENVDRIRGVLVGDYGIVDYGDALPARGYEASSKEKDQSIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9A4</accession>
    <name>A0ABR1X9A4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674033.1">
        <property type="nucleotide sequence ID" value="XM_066806737.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039797"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8092061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="653" mass="71911" checksum="520DA488C568FF50" modified="2025-10-08" version="1">MQRFHVFRAWKVEILSVLLAFGLITSIAALLTLNNEKPVPDWGNHINFNALLAVVSTVLRATLVIIVSSIISQRKWECRGIFGALLLLPTIIRRDAVALSAIIVLLASFLIGPFVQQASHTEECWFALPGPNASLPSAHYVPRLWGYSSTRSSPIQELLGLIMSAAMAPDGPGNQISATCITGNCTFSGENQRGTQNTTHSTVGMCNKCVDVSSLDYVHESKTLRLKNVPKKYNISDHDYLAIIRPIPDLAWLGDLLTPELRAISRWAYINSTSLAKDKSGEKAVAAVCSLYPCLRTYNASITHNQLSEREVRSDPMRVILPEGFPSDLIVQGELWADPRSQYAAVKSPCVEMDGGAVNLSPNISSHSAVTELALYDFTDYGLAPYHITRQNITAPEECIYRHDAHFSGFISDTFGEIVFNGYCDYSSADGGVLCFTNPDKATDSGDFLDSPGIWGVILALYNNGDAEFSIIARWFDAFANTMTNNFRSRPVWKDSILPFIFSRHIIEPTTVHEVKPQEMGTLSSSRRQLPFANDGEDAEDGAVDHDYEAEGTLADDHDDDPPTDSDNTLETHGGGVLLEESEMKAMGDRILVTFRWPSADTKEKTGLGEGGSEVEVGLPTPPLRRRIGSGWRRRRQQSRPDVDVDSLLGTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9V3</accession>
    <name>A0ABR1X9V3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7779 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674193.1">
        <property type="nucleotide sequence ID" value="XM_066804420.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037480"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056681">
        <property type="entry name" value="DUF7779"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25000">
        <property type="entry name" value="DUF7779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7779" evidence="2">
        <location>
            <begin position="190"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="428" mass="49129" checksum="6F105346E3C4D873" modified="2025-10-08" version="1">MRYSRYTYRARRPRRRWRLILDNINNASFLLKTLSHIKDGQTGHINEPNPLRLVDYLPTCENGSILLTTRSKGAALKLIKPSDIILVEPINQKEAKALIETKLGLRQDKVCIAALAIALECMPLAIVQATAYISRRAPQWSVQQYLEHFKQSDPRKAGLLRYEGGHLRRDVDAKNSIIITWQISFDHIRQSRPSAADLLALMSFFDRQGIPKSILRDRREGRRVGRGESIGRTSTFDDDVLLLQDYSFVQASENADNFQMHRLVQLATRRWLQDSGSHERWKEEFISRLSAHLPTGEYENWATWQMLLPHARLAHTLRPEIEASIIDWASVLYLMGWYLWRMGNGHEAESVSTLAMELRIEILGKGYGDSLNSMAIVGSAYRLNGRWEAAEKLEVEVIETRKQKLGPDYLNTLTSMANLASTYRNQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBC3</accession>
    <name>A0ABR1XBC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674768.1">
        <property type="nucleotide sequence ID" value="XM_066804995.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038055"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF12">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="24"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="2">
        <location>
            <begin position="226"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="61524" checksum="544A29D7CA6A4147" modified="2025-10-08" version="1">MRLIDCRSDPLQIKEFIGSPPEPFAILSHTWDAQEVTFQDFADVDTRTSARGWDKIQRTCRKALECGHAYVWIDSCCIDKTNNAELTESINSMFQWYSDAALCLVYLSDVDASDRDTLPRARWFSRGWTLQETIAPRKAYFYDGSWRFFGTRESLCRELSSITGIDASILSPPPGAEIRDLLADTPVARRMSWAANRQTTKLEDTAYCLIGLFGVNMPMLYGEGAQAFVRLQEEIIRDNNDLTLFAWTAKMENQSAGQQDSSTYRGILAQSPAEFAGLGNLVLDHDLKFNSDYSMSNKGLRIRTYLHPTQDAEDVVMPLHCHTLGLNGQRMPQLGLFLKPEGASVYIRTKPQMLATLSENILSSGENDIFVTKRYKPKRAPAAGTNILSAVYFNIQGLQDSSAVQLIETAPRELWDAQNRVFVTRGLRSFTAFHKFQLTGNYIGHLIVACGFSEDNKTPWVHMEDVLGTLYPAANVRDYGAVARIGAAKGGLKKRKQDLMMFVPTSNTMKARFGVAKVQCEQQTRNGEPVLVVNLELKKNNAVAFHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBI3</accession>
    <name>A0ABR1XBI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short chain dehydrogenase/reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674779.1">
        <property type="nucleotide sequence ID" value="XM_066805006.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038066"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="295" mass="32732" checksum="B9B00CA45FA94AF2" modified="2025-10-08" version="1">MTNIPARQKTVLVTGCTPGGIGHALCIEFQKRGLRVIATARNVDVLSDLTQQGMEALPLDVTSKESIASCHEAVGKLTGGQLDILVNNAGRTHTHPALDLDMDDVRQTFETNVFGVMAMVAAFGDQLIAAKGLRLLRQQGAVVSYSRTLRQELAPFGVRVMVCMAGTVKSNIASRGHRSLPERSVYQPIRDVFERRLVFSQTQDSMSTEEFASAMVDKALAPEVWWFLRAWVGRPDWFWRGGMASLQWWAMLLTGEWLVDYSSWRMFGLDKLQRIVQQDAAAQSSNAEDSKAKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBX5</accession>
    <name>A0ABR1XBX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674937.1">
        <property type="nucleotide sequence ID" value="XM_066805164.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038224"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="214" mass="24047" checksum="6AC54AD154B98A38" modified="2025-10-08" version="1">MSTYAPSYYLSPPQSPPQSPPQEPSLYQQQQQQQNQYLHPYQQQHQEQPQQNYQQPQQHHERPKPPPLLSVKVLFESSGNAGAGANGGSGRRVSIGFRNTQQAEHYAQFVRSKTIHHTERLSCKVQGRYVSVRLPTRVTEVVACLAGPGAGASRVGGFYFVFSDPILAQEWVDCLLLWRHVPGSKRKLYVERDVRDDVLHARLGITTSTGGRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBY3</accession>
    <name>A0ABR1XBY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000906</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674994.1">
        <property type="nucleotide sequence ID" value="XM_066805221.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038281"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="183" mass="19845" checksum="91DD4746DD4A39B4" modified="2025-10-08" version="1">MINAVLVFNGQGQPRLTKFYTQLHTAAPDIRDIHLVSNRPDGACNFLPLPPILAASGTSHSASEPHNDVPSLVTYRHYATLYFIIISTSTESPLALLDLIQVYVESLDKLFENVCELDLIFNFETLHSALSEMIVGGVVIETNMDRIVSGVKAQGTVAKRPVNEARPSGLGAGLGGTFVWPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCG7</accession>
    <name>A0ABR1XCG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675085.1">
        <property type="nucleotide sequence ID" value="XM_066805312.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038372"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="50504" checksum="F7E8D71C0EF9BA93" modified="2025-10-08" version="1">MDELEAICLEPYIERGGYFEKPGPEYRYKAVTITSFPAAAAGPEHLETELAEDALAGFMASPSPVDENAQPVPRLQLISIETNLRGPRYMIDSQVFKGLFKAASISTGDLWLLVHDRKGFLSMRRSEYQETHFAGHTNYTMAWSFDRHTLCIRAIWINLFRDDERRDFTSLLKRFKRYISSPLLLGFIYCLDSSSLTIANAKIYYDIERSVGYYGFGNDRAATRPSRVDLSELTRHISMIHNHIHLTSYFHYTANTSLQILSELEAHAGAVSLEEVASDPIRQRMHSTTLRLSQAFPVVRSRLLVRKEEIQRHMQRGRELSNLLFVLLTHEDALKGADLAKLGAEIAEASKRDSASMKTVAVLTMAFLPATFFAALFAIPSLDWKAGAAAATTADGSGSVIQSNFWVYWAFTLPATVLIFVIWLILNNRKWLVGAYKERVLCKRMNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCN5</accession>
    <name>A0ABR1XCN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675233.1">
        <property type="nucleotide sequence ID" value="XM_066805460.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038520"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="605" mass="65803" checksum="F09897D5F3BEFD81" modified="2025-10-08" version="1">MSCLCRKWRPPRLALPGGLHERQSQRRAPVQFLGEDQLARFERQFYPAGASNSSSNSSSNSAGQRRDRPLSAQAQLPSQVLQRLRTTPQEPTNQLHGADDDVPHRQLRHKKSMGFLNRVRDAFGLGRNKDREGASVSKVQQETEKRISLQHAPTHQPTHNQRPVHHMTKAYSHSNIPQFPPAFTALTTPVPGGAGTDRPSREEIMASYNELMATGFFQSHAIQSTRQPPPGSRIQRETAGHSMQAQPLPRIDSPADELLQEASPDRPKYSVMPDSPGSTKSPPRQSFHMHRLAPPPLSHQKLEAKAKASRESLRYNLRGRKRSRAEADINVLATDIPLPQQNKAGGIPLSPTGSSFGSIFSSANGSSNSGQGIIRRVSKKLRKMPSGAASADSSKTTSPAKGGDSGRKASQNTEMSIRLRSPSPDSPGVRSSMAGTRSERMPTIPPRSGSVAGAGGANRLRKKAHQYSPQARRQAHSNNPSYPPITLDKYRGLPIQMPSSNRPPGPSPNWSVEVDVDIGPNGESSSTRSSLDSNKGRGITLKDALSVAEPLCVVPDANRGIPMVPQIPDTFLKNGLYGAKGLQMEAAARNENHRMDVDCQFGQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDH4</accession>
    <name>A0ABR1XDH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UBP9-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001404</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675492.1">
        <property type="nucleotide sequence ID" value="XM_066805719.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038779"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17041">
        <property type="entry name" value="Ubl_WDR48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051246">
        <property type="entry name" value="WDR48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021772">
        <property type="entry name" value="WDR48/Bun107"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862:SF14">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11816">
        <property type="entry name" value="DUF3337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="306"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="659"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="371"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="398"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="416"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="663"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="714" mass="78035" checksum="33012EA3989B26BC" modified="2025-10-08" version="1">MTASSDQTIKVWSVTAGRCMDTLTMHNDSVWSLSSDHPKLSVFYSSDRSGLVVKTDIRGTSETDQGLSVALAQEHGGVSKIVTTDDYVWTASASSSINRWANVDTGPGALMPDEYRAARASMLSSMSEQAREVPATGESKIPANSILRISHTATFPPQTLNSSESNLAAQPIELVDPIVANAIEPIYRLPKETIEGQNGLCKVIRRFGKRHLEDVEPEVNTTEAVAPWCSIDTSSGNLAVVLEPFNCFDAEMYADELVTSEPIEFRDDQRINLGKWVLRYLFANLIDEEIKRDEVHRSKLNEGVAKRQAAARANPPSSIQIPTSPGWEENESAVITPKGNDNYPMTPSMAISVTTPGLGAHLPGVPENAAAPTSPQEKKSSQIARASNDDYFSSNGITSAEAPSKAPATPATPATAEKESETPKSPTEAKDNGKEEKKDEENKSESSSNHEKEVDDSFLGVLQRLHNAYDKDLQDTPDKFVETKITPSLPSDTPVLKLPAGTRVIIQEETSGGSADLYRGTVETVGHDADMIEQKAPMWLGDVLLTNTIPSKEPVKVSFILHPWQDTLPSIATTDGNNRLNANRMLRVKKILSYVAERIDPSFHEADENALKPEEYLELYCNEQLLPINMSLATLRAHIWKGGSDVVLHYKANGRKELPRELSQPMEQPPQSQSQPQPMEQPQSQPEAQPQPQPQPGEQSSSSNTVVETEPASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDJ5</accession>
    <name>A0ABR1XDJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675406.1">
        <property type="nucleotide sequence ID" value="XM_066805633.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038693"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="129" mass="14816" checksum="D076827566855E66" modified="2025-10-08" version="1">MDNGSERKPSATPNGQERSTSESVVGDRIDIFETKLFFLHPAIPPPAPYTWRVEEVRVGCRQFWRIPIFQAPYSLRHQSPSTPSSCYATTFSCLLSILACFTTRLALFFYNHATSPFLSLSMGRYRFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQA9</accession>
    <name>A0ABR1UQA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HET domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660525.1">
        <property type="nucleotide sequence ID" value="XM_066819640.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052700"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="45"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="715" mass="80402" checksum="3246D7A5E8D156E5" modified="2025-10-08" version="1">MNPYYERLDPSRSEIRLLTLLPNDDSDAEIQCSLQVVSLDDTTEFEALSYVWGKTVCSKPIFVRGEPLHVTTNLDRALRHLRLPQSRRVLWVDAICIDQCYPEEKNTQIPLMARLYRSAKSVLAWLEVPNEAMEAAIRWAHEYISETTTAGSASSSSPLSGSATQVDAVEKGHSEELEYIARLGQVLDGFGQLKDSEYWKRMWTLQEYRLPEVEPVCICGQYSFSATQLLDRAEVPLIRAFLNLVKRDPEGWPRSSSLSRNIARLRQLTRASLSNKELETFKGSAAYRPLLFSLKVGNEIIERLLAHLEVDVIVESLHRSEEVTANLLSEVRALGSNLELPTAGSKPYIQREGLAMDSAMRLTAKAAAMASLESIYPSFTFSNFRHCMGDTSIATVMLLSDSLDRQCSAMQDKVYALYGMAPEKIQQLYPPDYSKHPGQVYQETAAYIFEHEHEGVYRMLLSYNFRNLEAPSMFSSYPSWVPDFTDVSTRIGPLLNADRVTQRLIGWARNNPPLLLDDGQTLASFAVSLGAAEIILEFEDTFSKVIPPVVAMLNGDHLPKYNCGPMPHMLPGRENRCYVEAFTRLYAGQAVGGQGITVHRLKASLMELKHNPSSAPSNEALSCMVQLMGQKLVVTDHGYLGLCPPHTKNGDLVAIWPSLRGPVVLRQYSEPETSIHIHWKLVGSAHFQELVDGEWLNDKYVDEILEQKPLLLFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1USZ7</accession>
    <name>A0ABR1USZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660565.1">
        <property type="nucleotide sequence ID" value="XM_066819680.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052740"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="78"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="304" mass="34636" checksum="1E1801F041130956" modified="2025-10-08" version="1">MPPSCEFLLPGAIEGFNLGSKKWVALNVNNFLPEVDWNKNAFKQLVLDEKTKEMIHALVVVQKSRDKAMDDIIKGKGNGLILLLHGSPGTGKTLTAESVAEIAEKPLYRVTCGDIGTEAQEVERYLQTVLFLGKIWDCVLLLDEADVFLEERTMADLARNSLVSVFLRILEYYDGILILTSNRVGTFDEAFKSRIQVAIHYDNLTKKSRKAIWRNFFDMIQESDEDANMPELEGRLDDLALEEMNGRQIRNALLTARQLAQHRGERLDWEHLNQVIKTAAAFNKYLKTVKGHTDDRWAREEGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUI6</accession>
    <name>A0ABR1UUI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="2">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_014671</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661173.1">
        <property type="nucleotide sequence ID" value="XM_066818985.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052045"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07106">
        <property type="entry name" value="ALDH_AldA-AAD23400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044086">
        <property type="entry name" value="LUC3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="29"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8062574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="467" mass="50544" checksum="FEDBA5742D1AB269" modified="2025-10-08" version="1">MSATSSYTLDDCETTFRNVIDNELTTTAETRRAVDPSTGKPLFEVPISTQQDVDRAVAAGQAAFPAWRDLSTDDRAGYLLKFADAIDANRDGLGALLGKETGKPPQGVGMELFHLGNLIRMIVPLRIEEELVEETEERNVVRRYVPLGVGVGITAWNFPMGLGVVKLAAALLVGNVFVWKPSPYSPYTALKLGELAARLFPRGVLQVLSGGEDLGPMLTAHPGVAKISFTGSVATGKKVMAACAATLKRVTLELGGTMRLSFAAMWIWRRWFPSGQICLAIKRVYVHESIYDAFLAAFIEVVKTFKVGASTEADATLGPVQNSMQYAKVQDLYSDVSKQGLKVAYKADLSTPSGGFFLPPTEPFGPIVPLLKWSDEADVLHRANDSLLGLGGSVWSADTARAERMARQLEAGTVWVNSHFEITPNVAFGGFKESGVGVEQGTDGLKGWCNHQSVWVRKSRVAAEPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUL1</accession>
    <name>A0ABR1UUL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661210.1">
        <property type="nucleotide sequence ID" value="XM_066819022.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052082"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="310" mass="34850" checksum="E4D4F5EAFF731519" modified="2025-10-08" version="1">MESSFTDPIGCFYKSLDDFEASVLEYLTQTDDGVNLIYAHDKSYKTSPASPSHTTEFASTINESSFDSNRWSKALLDTDCWPQAPLGLGFWPEAPLDSNGWPVGTTDFSGWLLEPEKIPSSSIDLPLNSYDLPFCPGNVHKDYSDITNWSLDLFGSGSARTFSVEVSCEDVAQEAVLYPPSGGDSDLGHLEQGTIDNKCPQELRKRGALALETPSQPRRHKRRKTNSRSGPSKRKAGSIFKFSVEAVEWHHDNYTPLSHRCGILGRWRRVLSYNIKERDYFFTSPLNVSFKIRPNGYELPFNVTLDTQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUZ4</accession>
    <name>A0ABR1UUZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661345.1">
        <property type="nucleotide sequence ID" value="XM_066819157.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052217"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="332" mass="38217" checksum="2B1A9078B6AC3CAA" modified="2025-10-08" version="1">MKDLPGYQDGRNKQQLAPLQEWVSQSKELACPHYRINDPSLRTNLLHTIRQSYPVATILGQVTRVERTLVDNWGKPWGCPICKAAFSIVYVKSKNTALGGGLLSIRLESSRSLLKSIAKPCDSRWLAQLEPSTETRSEDARGVTWCDDASCGTSRQRRKEALLIWLLDHGVKAQVPGIDSPPVAAGARGQWLWFAFWWFWTQAQVPGDSENSLRWWLTNYPDRELVSGSFFGKQHLCREIGTDDRHWNRAAARHAATLHADADVVRELLRVSILGDLNKYRTYLEGKPRSHLAVLRDWYWERKMLRANNETQDCHRDWLTDAMWYNYAISRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVG7</accession>
    <name>A0ABR1UVG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_015023</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661525.1">
        <property type="nucleotide sequence ID" value="XM_066819337.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052397"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050829">
        <property type="entry name" value="CorA_MIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47685">
        <property type="entry name" value="MAGNESIUM TRANSPORT PROTEIN CORA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47685:SF1">
        <property type="entry name" value="MAGNESIUM TRANSPORT PROTEIN CORA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="158"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="835"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1061"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="870"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="419"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1063"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1095"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1111"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1165"/>
            <end position="1174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1174" mass="134265" checksum="E309270F3BCB6861" modified="2025-10-08" version="1">MATLRGLNSTEVEDDLADFLGTTEFNDRGSYFQESNPRWGTHGKSSQQATADDRLRVLNKIIKELERVERIRGAISKEPSERHLVECLEKSRQSWVDSEEYKEGIGRGLVNDWSGRKRHDTSPDLKFLKEVRSDLQRATHSEPTSEVGFTHVFPPRSLELPRRIQRRPSATRVPRSQKSPTRLPTTNERSEKAETAKPVEIEYDADEDFNAYLIQYEKPSDNPNFEPSQMKSLEPKTRIAGSFPDQRIPIRHLLGEIEIKQPGENHQRATVEHRNKPSLPAGNLLKDPTPAANKIRYFHFPANNMAWAERAIALYYEDDEIPTSPGNQTKSKAARQSKIHTMLRPEYWRGQQQGDRGAPVHARHMRPLCETISLSRSRAKAISDREGLKKPIRFSQNVTDQEAPSQSSLMDLLSPLKKNLSQDQRPASESQQGETKPPVKGLDSFVDALNLKGHRLDIDEHRRVIARVPVKKDDQKKNQTRFGQYLSNAARFKFREPKGTSDQKDNQNRLGQYLIDAARLYEGITNYRDKKLLHKYLHVDPPIHPRRTLDQAYYWSLNTTQSRDRDQVVYRGTRAAVENLHQFDIAKQVWPKHEEQKESWMSKHDDDGPCQECQANIRKISRLIMVDQLWLWVLDEHTILTFFPRRYGTNKNDVTGVHKSIRMRLEKVSKSRHPEQQMGSVWDLALIIFDECTNTFFDRTKTPDRQPQIIDDFSEAIGNVVSIDRIQYKTTSVTDNVKTNKQTIAFDRLWAWTEQWKANSSKKRKSRMSELHVSLLDINPEGKLQREIKDIIEELEIMIHINRTHRTILRGFIHQVIHIMDPNGQLKPRISLHTVNEEQTEGTGPNPRANNKGSRKPSDFVNEADYDRFETKAEELLGKVTSRIEELEELRRSAKSTSDSVRLIKDLLALKQQQASVVQAWQATQQTEETVAQGRSIMMFTVVTIVFAPLSFMTSVFGMNASEFSSENSLTVFEELKYIHANGRPSSVPVSAATILLVLFLAFNPYVRALVKAAYYRISANLMTMQAWGGYSVYKIWYANNSWRGEEQIDKAHTYARKKKRAAREEVLKERRDKSSQENGGIQNEEGQHDNSNGGSDGQGGDDNNQGGGATTSTPQGNNHQRQGSDSVAENNGAVVPADAGKEPQITESEGSTRRLPFWHTLRRPKGEEPPSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWL2</accession>
    <name>A0ABR1UWL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660823.1">
        <property type="nucleotide sequence ID" value="XM_066818635.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051695"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053209">
        <property type="entry name" value="Gramillin-biosynth_MTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643:SF2">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="187"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="266"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="680" mass="76695" checksum="5EDFAC9D6DA60007" modified="2025-10-08" version="1">MVVVRTFTDPNFDKYLCAAVEDIRGVVDCIILQNRDITLTPEENLPKGAVFAVKEPFYVTFPGGQHGILVEHPSNLIELDISDDIYPARWRRELLAQYPNGARQIQAEGSRACREKKFAEAIRLWEMAVSLCTPAEKSMERGMIRNLALANLSLGRFQQAIADARAALPDTNATDEEFDERQKVLDSKAMFRAGMAWYGLRRFAAAIRWLDEALLLDPEAANISRGRDLALQRLRERDEGAYDFEGISASITLDKPHADVADFLDNAICVKIDSNRGYGLVATKDIPMGDIVLCEKAFVASFEGKESAAPFCDLAWPNANNEPTWGTLAQLPAMFMHKCLHNSASQGTREILDLGDGKPSIWSGELVDGRPAIDCFAVHRAVHTSAYTMDALHSRDAHFDIENWGTQRLKHSGLWRYISIINHACDANSVRSYMGDFMIVRAAKDIKEGDEITLAYNNSRVVHGDAMKLQAELEAKYAFRCQCTVCKADEQCPRQLLNTRRDIYAEFYYEFKLYLTSSGMSSPLSGVFTPPGASSLNHHPELGKFEQYHHLMKETYPKDVYGDIRPDLCPVDFACAKVCNDEIKTRPNVLLKWALRCLRDSGLRLVIDEAQERLSWDIAAGAVPMEFNVEAVLYACMAYNRLGQRKLAKQFRKLAKLLWRIYTGTPIGFKDKFQDPEIWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWV8</accession>
    <name>A0ABR1UWV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661139.1">
        <property type="nucleotide sequence ID" value="XM_066818951.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052011"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF7">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="901"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="932" mass="103730" checksum="B5A512707FC68A71" modified="2025-10-08" version="1">MSSYSRDSDVTESEVAESDEDNQSSGYSVWTSWKSQFNWNLHAIETFGDIAWSAQYQQLVLPGLEAGGTPIPLPLSTPRDAEVIRKACHQAPFGRGDETVVDESVRKTWEVGREGFQLLNPQWPNFVNALVKDASVALGMPQNVRADPYKLLLYDPGSFFKPHKDSEKAPGMIATLVICLPSIHQGGDVHTSHSGQKYVLTTSQPSAFDVTALAWFSDVTHEVKEITSGHRLVLTYNIVLEDGPSSRPSADGFALRQTVPVNMLKDAHAHLPDATRLFYPLSHKYSETGLSLHSMKGVDRARVYALQKACASSEYILLLANITRTYTGLAEGHYDEGYIEDHYHLTYAATGEGAPVCKTTMDFQPNFIGPDPYERDADSLDGDEHLGNETSPPESRYHDSAAVIVRKDDLSKFLYLRALSDDTLAANVAELVTGRFYSSRDQAPNTTVDILKHLVELPKRGMGKTLPKILSFAIKTGDRDLWDEVITSAVTDFHRLVPGSRRYGDDYHRSRGLRSHLGEMAINLYTLENVNEALDGLLKGLNAEGARQSLQSWRLSIPENRFNRSKFCLEWNEASTIMAILQKGKGQDWVNESPSAFSLLPALKSRAEKSLHLALIPDLLDHKEIPDVEAIIKTIFWGTIDQLKVDESDLERHFKYPYEVSLFMALAKKLGLHGLSDEADRLIDNCCGSIAEAHRPKPVQLQTNTGMWGGLHVYESPRLLAEYILADFVDVVQQSGRPAPASLKPFFESLCGSSGNFIGREPERCRESGPCKELHDFLVSETEEMHRFELPWEERSHLQRGLPGNLFRCKEVDKSKDGASPAALVVTKLGKEYTLDLDIHKKDIANLEKRLLAFRTPFVRAALGDELYEELVLLGGIRKPPPGEDKDKIVPLSCKEPAAWPSAPLQVSEKKKRPASGSFEQPAASKAGRRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXG8</accession>
    <name>A0ABR1UXG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661092.1">
        <property type="nucleotide sequence ID" value="XM_066818904.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051964"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051019">
        <property type="entry name" value="VLCFA-Steroid_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899:SF13">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="35372" checksum="D0B505C9D546CD30" modified="2025-10-08" version="1">MASINVNKVVKPLAILGALYGLHITYDLLHAVIPYLRPSKLDRYLETKDGKTPWALVTGSNSGIGKSFADELAARGFNIVLLGRSKEKLRAAKAELKAKHPSRKFRTIVTLPGQCTDPHKVSFPDIAKQVEDITLNVLVNNLGGAMPRAEFGTIDYYTPAELTEHINVMATFPTLLTGALFPALLRNGPGLVINIGSFADEGVPYLPTYGPTKAFMMTSSKELAREVQCEGRDVEILGLRVGLVSGTNLNKKKPSLFEPHADDFVKSALARVGCGRMVIGAYVPHALQMGLMGLLPEFVKEKAIAWQISGRYKEERERMAKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3W5</accession>
    <name>A0ABR1V3W5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662634.1">
        <property type="nucleotide sequence ID" value="XM_066816942.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050002"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047442764" evidence="1">
        <location>
            <begin position="19"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="133" mass="13733" checksum="F35783B3BD4F21AE" modified="2025-10-08" version="1">MQLSLAPLVLGLAGLSSALIADSAERVRNDDPVLVDRANGGANGNRPTPSGQCCMANTSLNEDTCKAASGQQGRCVPGGNTCGGTLSCVAQSNLGCTNSIQERGKNLCRAKVGNNRYQDGNRVISNLNQARVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4F7</accession>
    <name>A0ABR1V4F7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Potassium uptake protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_012804</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662810.1">
        <property type="nucleotide sequence ID" value="XM_066817118.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050178"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003855">
        <property type="entry name" value="K+_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053952">
        <property type="entry name" value="K_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053951">
        <property type="entry name" value="K_trans_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00794">
        <property type="entry name" value="kup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540:SF83">
        <property type="entry name" value="K+ POTASSIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540">
        <property type="entry name" value="OSMOTIC STRESS POTASSIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02705">
        <property type="entry name" value="K_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22776">
        <property type="entry name" value="K_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="395"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="443"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="473"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="506"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="532"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="K+ potassium transporter integral membrane" evidence="11">
        <location>
            <begin position="89"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="K+ potassium transporter C-terminal" evidence="12">
        <location>
            <begin position="594"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8066057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="772" mass="85549" checksum="537870F517AF73F6" modified="2025-10-08" version="1">MRKTAPEHSTPRITNGRVIEHRPRQRPPEEASLARVCSTTKTPIQQCVSNTSEKGQTVDDVERARRLDQEDFGNNHAQTYHGSLLFWLSFQSLGVIYGDIGTSPLYVFSSTFDRHPSWDDLVGALSIIIWSLILIVTIKYCFIVLSANDDGHGGTFALYSLLARSMKIMQQDPHNMRRATGSSHQTNKSASQRLRNFLEGSSTAKSTLQTIGVLGVSLVIADGILTPAQSVLGAVQGLQVANPNLGRPAIIGITCCILVILFLIQPFGTSKLGTSFAPIVTIWLLFNLGSGIYNLITYDYTVLKAFSPHYIFAYLIRNGYEGWKSLSGLLLAFTGVEAMFANLGAFSKKTVQISWLGLVFPCLLFAYIGQAAYISEDTTRTAYSNPFFYTVPPGTLYFSLVMAALAAVVASQALITSTFQILSQVMRLSYFPYVKSIHTSKRFHYHIYIPAANWLLMICTVSVTAIFDNTASLGNAYGVCTILVTLVSTFMVGLVAILIWQIRIYYVLPVFLILFAIDATYTSAVLTKIPEGAWFTLALASILSAVLVLWRWGKEAQWAAESTKRLRPESLLNLERRTPYLARQYGGARIGTLPGLGIFFSKSGDPNVVSTCFAQFLTKFAARPRVVVFFHVRSLPQAFVSPDDRYIVARADAQGFGPHSYRVVLRHGYADHVLRPGLDQEIIHQIERILSGGDAASLRELQVLRAAQNAQTVYVVGKETMRLPRQQVGIRVLLRRLLLQAFLCILNNSRAKMADMDLDADRIVEVGFVTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4P5</accession>
    <name>A0ABR1V4P5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012912</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662918.1">
        <property type="nucleotide sequence ID" value="XM_066817226.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050286"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="9">
        <location>
            <begin position="163"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="236" mass="26353" checksum="B96E45BA847276F9" modified="2025-10-08" version="1">MADKDAVGPNVRGLARAPARDDGVATYEDTDVQWEASIRSSLSHWDPEPGFAHVDGEVGGSGYNETKTDIIAIPCPGASPVDTWMREPLPDGYFGHPTNRELEAHPALKEFQGHTILSPAINRPLPKAKHLWIRQGIRREVNTARVMLYRHRELTEGLTLDDLAEDLLDQLRKTRDMSQNRPLFFICHSIGGLVAKLALAKASEREDMRWLIFHTHGMTFFGTSSLPNCAFLLLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V533</accession>
    <name>A0ABR1V533_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-ketoglutarate dependent xanthine dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012168</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662174.1">
        <property type="nucleotide sequence ID" value="XM_066816482.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049542"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051178">
        <property type="entry name" value="TfdA_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779:SF2">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT XANTHINE DIOXYGENASE XAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779">
        <property type="entry name" value="DIOXYGENASE RV0097-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="22"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="369" mass="41312" checksum="FCB8F59E2B6D8E6D" modified="2025-10-08" version="1">MSSNIRVEPVVFPGVVGNRLRASVSNVDIEHLTDVDFAAIREALFTHQVLVFKNQSHVTPKAQYELTHRFDPAAASKYGHGDTTTGNKRSILHPDLRTIPHQPQVQVIGHGRVDEYEGLRDLRLKHPHHRTFHATAVPDHEDHYFTRFYRWHIDAALYGADLAPPVVTTLLAVKVPGGGRRQTCRYEDGSGDELDVPLGTTAFVNGEAMYNSLSEADKEFARTTKVEYAPHPYVWMSSARSRSDGLGLVSEGLQTLPMCWRNPVTGRLALQVHPSAVRALHLGDGTVIDDLERVRETVHRLQRPGIAPRRVYAHDWREGDLVLFHNRGVLHSVVGAFAEDEVRLLRQCNIAARPREQLEEQKVAAATAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5G1</accession>
    <name>A0ABR1V5G1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear pore complex component-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663189.1">
        <property type="nucleotide sequence ID" value="XM_066817497.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050557"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012578">
        <property type="entry name" value="Nucl_pore_cmplx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28003">
        <property type="entry name" value="NUCLEOPORIN POM34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28003:SF1">
        <property type="entry name" value="NUCLEOPORIN POM34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08058">
        <property type="entry name" value="NPCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="288" mass="30315" checksum="60BE4982735B7CD5" modified="2025-10-08" version="1">MSSTTLQRPLTPTKASPAPPQDSPGTWRHPRLEEISKRQNAAIFGEKNVKKVVYNVAALIAMFAIQGFVSQWFSPVPPTIGRFATYIYRIAQLVPLYNIAVACMPLIRSPDEMADIALTPGQRKLLGLPPSSNPPTPGSVYSTPPRYSRTPSMSGSTGGKRNFSDSTVNVQTSPSLFRSPLDFGGNISTSSFGASSNFGASASAFGGSGSALAGSPLIQKAIHGARRSSFGSPSPMVGSINGGSIFGSGPESPSPSPANGKRSSVSLNNKWLYEKGRRSSGNMFLQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6B7</accession>
    <name>A0ABR1V6B7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GANP/Nin1/mts3/eIF-3 p25 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663498.1">
        <property type="nucleotide sequence ID" value="XM_066817806.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050866"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="2">
        <location>
            <begin position="227"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="613"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="946"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1162"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="643"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="673"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="772"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="801"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="834"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="866"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="946"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="966"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1099"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1170"/>
            <end position="1179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1271" mass="138822" checksum="53595FFC7CA669B9" modified="2025-10-08" version="1">MAAPNPFASLVAPASAPFGAPSQSPFNPFSGVDTAPKAPSPAPNPFAAAAKPNPFGAPATGAAATPAPAFGQANTLKANNTLAQKPAGLAHGHPNGQVNGKRKGGNEEQGRPKQQRTAPPKSANHLQPKENRQVDSNGRNTPKGAGREDFANTIKAQLARDGVKAPKWPSDPGARTSRAAMDTFRQEHKAYREKARKSLVKADLVDEEGKQRRLDEALIFKGICEEMCPEWEKIIRITENDVKLAEKVDRNGDMIPCPTKMVTRLARSAAGQELPLPMDVRSPAALRRSLDYMIDQLIPTDDLLATRHHFLWDRTRAIRKDFIPQGPAMNSEEVMDHIYCLETIARFHVTSLHLLSQPGFAAEDFSEQQEREQLSKTLMSLDQAYDSCATAGIKCENEAEFRGYYALFFANETGLKEKVQRWPEWLWESDGVRTAMCLVEAIENTSRLHGPLSPWAPADMAMNVASIFFSIVGSPQISYTMACFAEIHFSMVRQSMLQVIKKSYSRPRDGPKDLTPDFLRRKLYFDTEDEAIAFAELHGLQFEEDNNRRYLVLNPRQRMDEPRVPHSFSNGLVERKRSDRPLAEIIHETVYEITGEEMAEADHDEESLFVEGTPATGEAMSEVEEIVESETENEVPAPPTQPAPVSTPSLFSNTAGQAPQSSIGVPPGQSIFSQPSSAASTTPSLSTATAQSAPSAANPFAHLFGASKPATPTHEETAKPKADKKVTFGDSTFLGPAATPSETQKSTPSIFASLNKDTTTPGANDTPSIFGTAKPAPTATNPPEVSSSIAEKSPHFGTSPTSLGDTSTTNSTSTSIFSTMANPKPTSPAAPLGAPQSPLPSTSSPFPSGPTAASISPAPSTLGSLASTASPSIAPAPTTMPPAPAHKDPMGNFTEWYVLGDRGLMKDHLEEWAIAETLTEVWETFRAEEDERIRQEEDEKSWAEARAFHGKEKARAWNSPQSVAARRAEEEAAKQKRHEEALQLVRDRKALNKSKREKEFRESIQSQDEDIEQALLASGVFKGMRDEQAAAREAAADDDEPLTMLPSEMLRRGENRRREKHGMRPVSRSSVASTAKLGSKTAKLMALANGRDSQSVPPSSFRNSTFSSSFRSSLGVNKHRVEKTKKSRVKDPYWQYKVHGLVLMPDNKYAYQPEALEKFRKSTALESEPSDSLVSTPNGEAQRHSLFAVTDGLDGSHNSSLSPAISRVSSKRKRPVVLPDEVEDEDLAAYRSEASAPSRKRAKSDDESEADFLAQMNGLLQEVEDERKKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6P9</accession>
    <name>A0ABR1V6P9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">von Willebrand and RING finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013339</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663345.1">
        <property type="nucleotide sequence ID" value="XM_066817653.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050713"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF43">
        <property type="entry name" value="ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="137"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="634"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="228"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="570"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1009"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1053"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1174" mass="129114" checksum="CD8C893DF4DD973F" modified="2025-10-08" version="1">MFSRSSSKTQGLAKEQRARDAQVSSLLELGVSNKTSDSRSFRSLSSFKKKNRQPKQPQHPVPARDDWDNYPNTSFPEKNHSIAAGNIHGSPRRTPSLRSSGASVSSRDTVRAVSNMSGMMADRTRTRRERTFVGSECSVCEEPLEHTLRGERILQFQCSHVSHEACFYEFIREFESQYCPSCDAPLHLDTSRGGNVLDIGKVQSAAYNASHNSDGPAHSAEKITNMVRSASTSDSRSQHTPTPSGGPWDDPPVPSSRGPQSSGGQSVTRGSLRENRDRDSRDAPPSERYTTNSRHARSDSEATGAASSTGYAETAQSGPSRRHDYDLQAMETTPGSPRTMTRNPIPRLPSRYVEVPDNKWRPDPEDLGSVAPMPQQRIEDAFPQRPPSPARSNKPRFYPYEPPEVLEEMTENLRNRVDNWHGLDFNRFGKLRLYGTLRVGKDKVSWQELECFLFAEMLICVKEKKNLAAAHQWDENGNPRKATRCTLKGSILIKKHLNEVTETGNGRFGPSDNSERRTKLTQPPVDENVLTLSLSVSELPSFHLRFGNRNQLKLWQQALLDLNATEVSPVRSPDFDRADMSETDEDDWGRSQRPQRVSSQASSWGGPKSSTTAPTEYTNFVKSPLFSTVHVPIDVVVVVPISSSMQGVKINLVRDALKFMVGNLGERDRMGLVTFGSGGGGVPIVGMTTKAWHGWNNVLASIRPVGQKSHRADVVEGANVAMDLLMQRKYNNPIASIMLISDASTSDADSVDFVVSRAEAAKISIHSFGLGMTHKPDTMIELSTRTKASYTYVKDWMMLRECLAGCLGSMQTLSHQNVKLRLKLPEGSPAKFHKISGALQITKRATGRDAEASLGDLRFGDKRDILVQLVILPDTASQDQLPQDPWETIVSGLEALGGPMDQEDQRTLSVEELPLLQADLVWGDILREGSIIHLPRPSLLAITMLPPSAADQKKSSWQNAPPIPPHPNIVQRRMELLTSDMLTRALTLVSRGQHDRAHTLLNETRTILRGLGKGGLPPVPPPPLPGQKSAPSTPHPGADGSPTSATPDRKHSPSPTASAASSAVNGYPPPLSRSRSNDALTLRNTVGIDNSTVSALDAELEASLEWMNHPAVFSRDSRKAVLQAIGVISSQRAYTFRTPIESLWAARIGGVKKLTDKSREWRDDAGGEGIVEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6Q0</accession>
    <name>A0ABR1V6Q0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein CASP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_012405</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CASP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662411.1">
        <property type="nucleotide sequence ID" value="XM_066816719.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049779"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012955">
        <property type="entry name" value="CASP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057476">
        <property type="entry name" value="Cux_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043">
        <property type="entry name" value="CCAAT DISPLACEMENT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043:SF2">
        <property type="entry name" value="HOMEOBOX PROTEIN CUT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08172">
        <property type="entry name" value="CASP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25398">
        <property type="entry name" value="CUX1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="659"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="Cux N-terminal" evidence="14">
        <location>
            <begin position="31"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="CASP C-terminal" evidence="13">
        <location>
            <begin position="422"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="477"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="706"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="150"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="265"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="414"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="518"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8065658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="730" mass="79763" checksum="AFF63AFFE355FA08" modified="2025-10-08" version="1">MADVAEFTALEAAAGKPPAAETPAATLHPENTNKFQHAISAWRNVDLTSLVSTLDNTASDIVTYQRDSTIQRKDLAQKTKDFRKHDDATKLTEIKGLLKAYQTFIDLLTNHSKSTNSAFLQVYSALSDAPDPYPLLEASVDSMLVSEDTLPKLTEENQHLQKNITSLTSQLEETESRLQSESTARKQLEGNLESKVKEVESSWAAVLEEKKDNWEAKEKALEEKVENQERLLTEIKASYEVNQRLKGSEDAESEGNRGHVTSAELEMVNSDLERTSARLAEVEARNEQLRLDLAQSKSHVQTQGPAPEDDPAYIRVRSENSSLIRKLDSARVEKEAYKRDIDTRLRSLEREAGLLKDERDALKAKVQKWSDYDDVKQELEVLKSIEFATGDDEDMIASAADSNGAATKEKGGHLGAAATRLENLQEEMSRTNADLERSQNLNTQLENDLANLQAEGQNAFPSGASVAGTYTRYAPSVAPPRTMRGGRTSPTSSIISGFNPRDGGFGGGEPMGGGSGMLPMITAQRDRFKKRITQLENELSESHRAISQLRQETAALQKDNLQLYEKTRYVSTYNRGGASASSSSAFSSNPNPSTIAIGGSANPGIALDRYRKAYESNISPFAAFRGRESARAYKRMSWPERVVYSVTRMVLASRTSRNLFAAYCVALHLLVFCSLYWLGTADTAQHASNLGGGVAAAMAAGGGGSAGSGSGSSGSRAKHGDWQEEGFNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6Y2</accession>
    <name>A0ABR1V6Y2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mRNA 3'-end-processing protein RNA14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013704</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Nucleus and/or cytoplasm.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663710.1">
        <property type="nucleotide sequence ID" value="XM_066818018.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051078"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045243">
        <property type="entry name" value="Rna14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980:SF0">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980">
        <property type="entry name" value="RNA CLEAVAGE STIMULATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Suppressor of forked" evidence="6">
        <location>
            <begin position="207"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="568"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="820"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="576"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="877"/>
            <end position="888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU369035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="953" mass="106567" checksum="4D293649B18FAF0A" modified="2025-10-08" version="1">MASENPEDGYAQHGEETDSTWGTGDGVGASEDQQHTEHDSHEQAQEPISADPSFNASGDPTSDADEDGGEYDPESISITTTVPVLPPASHTPVAAAERDEATASPRPSKKPKKAGGFIVGSSDDEDDSATPPPAVATTAANSLKPASSDSQPRAFTHSPLQQSTTTAETINDPAAAGPTAQVSNGLGIVTTTPSINEAKSRLPTDIIGILEDRIKDDPRGDMDAWLALIEEYRRRNAEMWVQYLQQELSLDNFAEAEQIFQRTLMTIPSVQLWTAYLDYIRRRNDLHDGTGQARQIVNQSYEFVLDNIGHDRDSGKMWHDYIQFIKSGPGQIDGKGWQDMQKMDVLRKAYQRAICIPMSNLNILWKEYDQFELGINKVAEKSPSYMSARSANTHLENFTRGLQRTTIPRLPPATGFEGDQEYLEQVDLWKRWIAWEKDDPLALKTDEPETYKSRVIHVYKQALMALRFWPELWVDAAEWCFDNGVLGKDGSDLGLQFLVDGITANPESALLALKHADRIESTHPSGEGEAGKLALSHAVRAPFDTVLGALYDMVKKLKDREATAVGYIENDPSLAESDEPQMETDDGELAEKPAKTSLREERIKAVREGFAVQIQMLSQQISYLWIALTRAFRRIQGQGKGTPTSGVRAIFTEARAKGRLTSDVYVAVAHIEWDIYQDPVATKIFERGAKLFPEDEHFMVAYLKHLHSRHDTTNARVVFSQSVKRFKEKPELTPKLKPLYAYFHSYEAKFGELAQIKELEKQMAESFPEDPSLAHFAARFSSERFNPISARVIISPSAQMRPKNIMPSVEQINTSARVSPHPSVMADRSPRQQFLPVVNSPKRPYQPDEDDFPPRKVQRGASPLKGAAGRRMDQQRRAQGQGITYSSTPAPISRDITFLLSLIPPPHQCDAQRFRSDAMVRVIRDTIVPDYNEWRASQNSGMRSDQASRMHHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V790</accession>
    <name>A0ABR1V790_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663555.1">
        <property type="nucleotide sequence ID" value="XM_066817863.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050923"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="647" mass="73039" checksum="9402B38C902D3A83" modified="2025-10-08" version="1">MASFADLPPELLRPIIEYAVLVREGEIPRSYTHVGLCAILRLREVNKVFDAEVLAAVARLEIFRRLARNTRAIPWYETPWDPPRTGEEPAVTSETRFLARYLLGRPHAPEDRWDANLSAYLNTLLDLVLAAEGSPAADDDEGRLAYMLCLCRHYMGVRLAQARERMWGWAFEWPAAMYSVPDLFNRTISTFASGPLERHLLACQSVIDASAGGLTSAFHADPDFAPWLRDKDKRGSQPLGDSLRAFILGSTMDRFVAVLDPIRGVGFNDDERDCLVWAVQSGQLAKVKYMMSWPGHRSHQPFGDKFERAVVEAVRLRRRDMVAYLFGLHRWTGRLCAWIPVHARSVDVTTMALLLACRHGDLETVRLYFRYMPEAEFARQHPHLRRNALMYACRSGNPELVSFLLSRESTTTVTEGVVEGSENDSRCRTCNNGTQSLSEDGYQTCCGEEGGFGPIFVAATNGNTRIAQLVLDAGRPVSAIQYQKAAAVAVELGHDRFLQWILEHAGPELTEPTAEFDLLGLTCVRGSVRTLEVLAANGLLQDRLLWAEDCCLPYRLEGNARVYPQRRYEKPALVAMVWKRDDILQYLLARGFEGVADPLETSVKDGWREGWIPRRPTPKVKPFGWRGIESVTLEQKDEMLFKGVYIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7D4</accession>
    <name>A0ABR1V7D4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663845.1">
        <property type="nucleotide sequence ID" value="XM_066818153.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051213"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8067092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="77" mass="8154" checksum="3E86F68960FD0BEA" modified="2025-10-08" version="1">MDSGIRAICVSDPLVAKEDPEGIPCSPATNQVVRHPQAADAGPCLEQFGGVVVPPRPLLLHSQAQPFQSRTHADNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7J1</accession>
    <name>A0ABR1V7J1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663906.1">
        <property type="nucleotide sequence ID" value="XM_066818214.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051274"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="245" mass="26749" checksum="8BEE4D288BA1F9D0" modified="2025-10-08" version="1">MGETRESAEDPFKGDGTDWTWLYVIIFLIPVIFLAIAVYSTWRDRRAAAAKAKNDLETGRAAKLDRYYHPWKYDAAESSSAAGRNGANRSKLTIVTAATTTATTTTAESAAAAASAAAAGKTTSRHPNNPWEPATPRSGGGGGGSNNNINNRRNHNSLTPVTPRSRYSTNPYRPQEYQQQQHQQESSSDQDVDAAPYLPRPTAPLTYLVPRRPCMARPLRWGIIRTERRSRGPGVTAAGFVHVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V871</accession>
    <name>A0ABR1V871_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664130.1">
        <property type="nucleotide sequence ID" value="XM_066818438.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051498"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="365" mass="39219" checksum="2F1FF8544A2B4E6F" modified="2025-10-08" version="1">MSSQLPNFSRTNRPPATSVAGRRRGRYNDATTSIHPSSPPPTYASGAGSPLSRHQHDTEDDGVGVKAATTNAAQQAASRLGGLGSHDRRPPPPRARLRTPSVSNASSFCRRLRNESAIRFSPVDLDLALVELASVDELSLIESYEKEISASRHTSLDVAASAAPLSHVYRSSSTQTEMGRRTRQLPASPTAVATSGSSPGHPVRMHLYPHSERGEEVNSRGGPRPAHPGSAGLEAPRPYYPGALAYKRHHPHPRRRPKQISSGPTTSSWPRATSKTGPSTSPSVRRRAPPRPLPLDLKSPTSPLIHEMKSDVGGGQGSPSTPEAKAEEPIGPDDEMSELPTGFRFYMIVVSLLLCVFLMSLDLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V920</accession>
    <name>A0ABR1V920_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cardiolipin synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_013306</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663312.1">
        <property type="nucleotide sequence ID" value="XM_066817620.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050680"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF60">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE (CMP-FORMING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8066559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="24913" checksum="952A530ABAE8A260" modified="2025-10-08" version="1">MVSMTDPKPAPPSGLRKVLPIPSLTPHEDIYTIPNLLTASRLVLAPFIGYAILHDAHAWTLGLFVYAGVSDLLDGWIARRWKLQSVVGSVIDPMADKILMTILTVCLATKGALPVWVAGIILGRDVGLGIAAIYYRWISLPPPKTFMRYWDFSLPSAEVRPTTISKYNTFLQLALMGATVVSPLLTVDVAVALTGLQYTVAATTVWSGLSYVFSKDAVKILSDSKAKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAM5</accession>
    <name>A0ABR1VAM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664124.1">
        <property type="nucleotide sequence ID" value="XM_066818432.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051492"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046072794" evidence="1">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="80" mass="8504" checksum="41DEFD0136F158A7" modified="2025-10-08" version="1">MYSSIKIVSLLYLAALALANPAPEAFRLDNGQETVEVALGARDRGATLEARGNLDCKGSAYCERLGGSCDDAFRQIIPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGQ8</accession>
    <name>A0ABR1VGQ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010583</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664188.1">
        <property type="nucleotide sequence ID" value="XM_066814898.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047958"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF4">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_7G04540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="363" mass="38907" checksum="9CD06EB4AA5D5C78" modified="2025-10-08" version="1">MISSASRSAAIALRSNPPHKSSRLLATFCRTYSQSTSPTSSRQLTSSAAITRNPHTKPNNTSNFTQSVRMASNTANVHFSRDKLFDLTGRVALVTGGGSGIGLMATQALVTNGAKVYITGRTSEKLDKVVEQYSQGPDSIIPLTCDIGKKEDIANLVKEIEKRESCLCILVNNAGISTSTVSVESKSAEEMKQNLFDTENATFEEWRESYNTNVASIYFMTAAFLPLLQKSSEKHAGWSGTVINISSISGLIKTAQHHFAYNASKGAAVHLNRMLASEVASQGLKIRINSIAPGVFPSEMTAGESGGDQKSHIPKDKYAEKVPAARPGKDEDMAQAVLFFAANQYLNGQTVAVDGGYTLVAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH26</accession>
    <name>A0ABR1VH26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010746</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664351.1">
        <property type="nucleotide sequence ID" value="XM_066815061.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048121"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="10"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="260" mass="28078" checksum="D5F7ED093890F0FB" modified="2025-10-08" version="1">MEAIHKDDLCTLCEQLLYDPIVTTCQHLFCKSCMEEHALGSLPDPAILFDVDTIPANNLQIANLLNVLVARCPVCHTKSGPGVTPSPEKCTELRTKYPIAYAEREAKAAHAEPGSGGDGGVQTITVCIGNSHQAVPIPQGSSETKREHKWAIFAKSSSDDVIAYVRFSIPGMGFYPAHAPPFRVAGSGSNTFSAKVTVVLKAGYIWDSEHAEDTTGGGYKRAVIAQWDMDFGSYGGKGSMGLWRLKFKPGTRESEEASQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH49</accession>
    <name>A0ABR1VH49_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010762</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664367.1">
        <property type="nucleotide sequence ID" value="XM_066815077.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048137"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF33">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="241"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="608" mass="66999" checksum="6450C99D59283740" modified="2025-10-08" version="1">MGGGGYLPYSQPGRSKSRRLSSALSKYSTDTDHLTPVSATAADANAGTESIDPPAEDASGRYGGLLPLLPRLRGSNTLDMFTGWLDLAFYRLGIPRQLGANSDAESGKEKAAPIALSLAPPSLPRPDVCHTALRSYFSTINQIFPILEFQRIQGLIESTIKSGPPVLSHLGDVVSVLQIQLVMVLGSIGGDAGLDPDLATQYVNYCQTMLGHVLSVRSLEAVQCALMLAIALRQRDQISSSWHVTTLCISMAQSMGIHRRRTPSRKDPSPVDEESEEKKRRTWWSIFSFEKLFAFEFGRPSFIRDADCNQMEPTFPPNPQSAWSFRILTSFARLLSQINEAGIRCRIREERSSQRNIEGIIRDKIRLTGETVHLLMQWADSVPERLRPSFLISNEAIRIAVERYAAGQPWSSVIQNGQTAAANSARTVIKLLIDGHELGTTPALSTLATPLHAVYVLAVHLLTHPGSRLAHSDLNLYERHHSDRKLQRVLKSLTDQISAAVQAGQSKSDFRRSSTAYSNEMTTVNSKFPSREMPVFSSPQVTRMPPLESVPAVNSVAMETTEMPTGSMGDASFRDVVWPGGTVDDITWDWDDFSQVFDLSFGEAPNCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI55</accession>
    <name>A0ABR1VI55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011102</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664707.1">
        <property type="nucleotide sequence ID" value="XM_066815417.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048477"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF57">
        <property type="entry name" value="ZINC FINGER PROTEIN 154-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="262"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="47"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8070899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="297" mass="32119" checksum="EF95C46FDDB46243" modified="2025-10-08" version="1">MATTIYTAQPGAHYGYPQPPPSPPMDETSRCSLPSISNLLVMADAGSPTTESSPASQQAQSIKPETRPSSSHYTSNGPCRSALPPTPPMSSESFEGYHSPSTRSVSQVSVVSAPNYYYESTPPLESDIQRHQQMAAASVPRVPIHASSYAQQTFAAPQYMAQPTMASYYASPMPPAAAQSQISGLYYQRPLPQGFPPLPVAVPMAPASGSNPWQHHHYISPSSAASFPQSQDRYICQTCNKAFSRPSSLRIHSHSHTGEKPFKCPHSGCGKAFSVRSNMKRHERGCHNFESGTPSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI75</accession>
    <name>A0ABR1VI75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-(apurinic or apyrimidinic site) endonuclease 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_011045</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664650.1">
        <property type="nucleotide sequence ID" value="XM_066815360.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048420"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09088">
        <property type="entry name" value="Ape2-like_AP-endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020848">
        <property type="entry name" value="AP_endonuclease_F1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF4">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00728">
        <property type="entry name" value="AP_NUCLEASE_F1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GRF-type" evidence="13">
        <location>
            <begin position="568"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="381"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="513"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8070842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="627" mass="68834" checksum="CEE3590DD1BADDDB" modified="2025-10-08" version="1">MGVRITSWNVNGIRNPFGYQPWRENRTFEVYEQHMFGILEADIVVIQEAKIQRKDLQDDMVLVPGWDVYFSLPKHKKGYSGVAIYTRNSVCAPIRAEEGITGVLCPPNSTTKFCELPEDQQIGGYPRPGQLTGVVDEATLDCEGRCVILEFPAFVLIGTYSPATRDESRDDFRLGYLEALDVRIRNLVAMGKRVILTGDLNVVRSGADTAGLAERLRKEDMTMQDFFSAPSHRLFNQLVFEGDVHGQRDEGREEPVLWDLGRLFHPTREGMYTCWEVKKNARPGNFGSRIDYVLCSDNMKSWAEDSNIQEGLMGSDHCPVFATFSDVVQVDGKDVHLRDLLNPKGMFQDGQRLREWTAKDLLPLSAKLIPEFDRRRSIKDMFFKKPTSTPKPSATPTSVEPSSQDTTVPEPAPSPIRERDTLQSSQPNASTSAASPAKRSASGLKRTPSAASTGSKPQKKAKTASGKEAAISKGQSSLMGFFKPKATSTTADQPAGAGSDSNANPNGMDGSTDAPSASATKAQTTTDGISQIDTDTVQSPASPAKFIDPIESKESWSKLLGKRVVPKCEHGEDCISLVTKKPGVNCGRSFYICPRPIGPSGQKEKNTEWRCGTFIWSSDWNGNSAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ48</accession>
    <name>A0ABR1VJ48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase- family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011464</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665069.1">
        <property type="nucleotide sequence ID" value="XM_066815779.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048839"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF17">
        <property type="entry name" value="O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="253"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="418" mass="46293" checksum="B39069E239C59451" modified="2025-10-08" version="1">MAKGIEEPVTVTVATTTTPSNLSAVPHLVKELVEEAKCLESGCNEARQALAIKARTLVQALETPRETMIKHCWAQPAVFAAILCGNECGLWKLMAKNGVRPQRVKELAATLDVDPVLLSRLLRHLGAMGYLLEVGEDEYKPTSFSLSLSLPIMNGGYPSLITMGGPAFLNLHEYERSRDWKNPTDAKDSPLMHAHKTDLNYFGLAASRGYLEDFNNHMGGYRQGRLPWMAPGFVPVQEVLVKGAGPSPEAVFMVDVGGGLGHDLLEFHRYHPAVPGKLIVQDLTQVVGSIVPSEENRALTPMAHNFFDEQPIKGARAYYLHSVLHDWPDDRASEILGRLKAAMRPGYSKLLINENVIPRTNAYWETSALDLVMLSLLSAQERTERDWYDLVEGRCGLRIVKIWSGGRGVESLIECELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKX4</accession>
    <name>A0ABR1VKX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664326.1">
        <property type="nucleotide sequence ID" value="XM_066815036.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048096"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="192" mass="21693" checksum="76A5498EAB275907" modified="2025-10-08" version="1">MAQIIAMPEGFIGEALRVNQSSIEQTILSTNRPTVSHLNMSRTQVNVVVLFQALHRTQQHRLLTHRVAEDVAAALGHDSPAGANAVARIIDHYTAARLEFNRQNKAADKYHYRKHLHVLVDEEIRWRLTCGQNVQQVTPSISQHEAKRRYVGEMKQLISNSIKFLLEVGLPDLTNPHHSPRNDSFGKLKDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VM32</accession>
    <name>A0ABR1VM32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Cysteine proteinase 1, mitochondrial</fullName>
            <ecNumber evidence="2 9">3.4.22.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011187</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.</text>
    </comment>
    <comment type="function">
        <text evidence="7">The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.</text>
            <dbReference type="EC" id="3.4.22.40"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. Binds to nucleic acids. Binds single-stranded DNA and RNA with higher affinity than double-stranded DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.40" evidence="2 9"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664792.1">
        <property type="nucleotide sequence ID" value="XM_066815502.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048562"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00585">
        <property type="entry name" value="Peptidase_C1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004134">
        <property type="entry name" value="Peptidase_C1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10363">
        <property type="entry name" value="BLEOMYCIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10363:SF2">
        <property type="entry name" value="BLEOMYCIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03051">
        <property type="entry name" value="Peptidase_C1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005700">
        <property type="entry name" value="PepC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0788">Thiol protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8070984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="520" mass="57026" checksum="4B4D0D33AF34550A" modified="2025-10-08" version="1">MGSYPSKVSPETAAHEKAVLERLRTFQINEADDGVGGDNDDGFVYVLDTNEKTSGSSRHGSGGTRKELRVGAWQSKVLEDPKNRLALSALSGANPKDVLTQRSAQIADVHVFNVSLGPDSEGAPITNQRSSGRCWLFASTNVFRVALMKKYGLAEFELSQAYLFFWDKLEKANYFLENVVETAGEDLDGRLVQRLLADPVSDGGQWDMVYNLVTKYGLVPQALYPDSWNAMSSSTLNYIVVSKLREYALKLRKLANASTTTSATLSATKQKMMREIHLILTLTLGPPPSSTEKFDWTFKDKNGKARTVSLTPLEFTRDISSPEFRITSSAIAGMISLVHDPRHPPLSLLTVDRLGNIVGGRGVSYVNVSMGALKQACVATLRAGVPVFFGCDVGQSSSSVSGVMDLDLVDWTLGFNVDLLANTVSKADRLRVGASAMTHAMVLTAVHIDESSGKSVRWRVQNSWGESSGDHGWFVMSDAWMDEFVYQAVIDPRFLVKEVRDVLKKEPIVLPLWDPMGSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTA3</accession>
    <name>A0ABR1VTA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665387.1">
        <property type="nucleotide sequence ID" value="XM_066813425.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046485"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="91" mass="9031" checksum="FE35F194DF60ACF3" modified="2025-10-08" version="1">MCPKNKPGDSSGRLAECLQGTGVVGCASVAKGPLALAKSAFFPGPSSHSPFGEVLGQTKNHLVFTVVVVVSVAKARIAPSGIGGTIVAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTQ5</accession>
    <name>A0ABR1VTQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665576.1">
        <property type="nucleotide sequence ID" value="XM_066813614.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046674"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="entry name" value="Peptidase G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045909305" evidence="2">
        <location>
            <begin position="20"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="287" mass="30238" checksum="940CFC37EB82EBE7" modified="2025-10-08" version="1">MLWQKVAFMMSLIPSVALAAGIAIANSSTYAGGLVALPQSDSDTGPAVTTLEATFTVPNLTYASGQSGNGDPYRLAVQCGISAVTDANPNAACNHRGPHMGIFANLSSAGQSQQSWYNWPNLSVEGLSSAQDSLLNFTAGDEMFVTISLLSATNATYTFMNLKNENVTVTVAQDGGSSQPMCSGQGTTAYAGCYIGVTDASTMPGFVEIDFESVMVYDRSNTTHDFGLDQTVQFYQLVDSNGKLKAMPKLDDAYDFSVKWSENPDYGSGTGGAGTPPSPDTTTALRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTX5</accession>
    <name>A0ABR1VTX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Abc1 containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665650.1">
        <property type="nucleotide sequence ID" value="XM_066813688.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046748"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014144">
        <property type="entry name" value="LigD_PE_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39465:SF1">
        <property type="entry name" value="DNA LIGASE D 3'-PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39465">
        <property type="entry name" value="DNA LIGASE D, 3'-PHOSPHOESTERASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13298">
        <property type="entry name" value="LigD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA ligase D 3'-phosphoesterase" evidence="2">
        <location>
            <begin position="106"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="334" mass="37594" checksum="BB217B3F59D8336B" modified="2025-10-08" version="1">MEAHEKQDPSNPKPEASCSIIKQRNLEWSIELTGSPRDAATDSSEDEWDWPGGAKIQDHVGYFSGILSKATLSPFPDCLSHLSVAGYRKLYEDNFGNPRGAHFIVHQHDHPVAGVHYDLRLQINETSSASWAIMYGLPGDPNSQRLMRNATETRVHCLWNHLIETASVHTGSLLIWDTGNYTVLDRKSKHAPAEDPDSQQSDSSQDSGALELTEQEKLHRAFQNRKIRIQLHGTRLPQNYALNLRLTTQEDAAGRAKAERKPTTQRRRRRRPALQKNEEPVPPPLTSSSDNDGDPPSPSEGNSIKTGPSKRKRRPPKPNGGWRASKKYTEKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW16</accession>
    <name>A0ABR1VW16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010108</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666385.1">
        <property type="nucleotide sequence ID" value="XM_066814423.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047483"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF1">
        <property type="entry name" value="HYPOTHETICAL O-METHYLTRANSFERASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005739">
        <property type="entry name" value="O-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="166"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="339" mass="38240" checksum="ECA76D0410544CC4" modified="2025-10-08" version="1">MNALVEHRAFDHVPLDGTIGLEDLASKIGWEPAVLIRFVNVVLIQGIFEEPEPKVYKHSASSTVFREDAMRAYYQLGSWSVPSWWKVSDYLKTHAPEDVYDPLKSPFSYSRGAEGQTYYQLLEADLAFSDVWHKGMAQAAPFNPVLGMFPFRDMKEAVEAEPDRAFVVDVGGGRGNALVDVMRECGGGFGAPMVLQDLEEVLQGEDPVQIDGVQVMPHDFYNEQPVKISLPDAHIYYMRKVMHNYYDDKCRTILRPIVEAMGPTSRLLFGDMILPETAQPGDDALPFYMDLRMLMIGGTERSETQWKQLLESVGLVIVKIWRLPGAPHQATIETRLRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWQ8</accession>
    <name>A0ABR1VWQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Polyketide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_010331</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666608.1">
        <property type="nucleotide sequence ID" value="XM_066814646.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047706"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19532">
        <property type="entry name" value="C_PKS-NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF20">
        <property type="entry name" value="HYBRID PKS-NRPS SYNTHETASE APDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="12">
        <location>
            <begin position="926"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="2326"/>
            <end position="2400"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="926"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1075"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2403"/>
            <end position="2479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="2411"/>
            <end position="2437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="2450"/>
            <end position="2462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="2463"/>
            <end position="2479"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="957"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8075668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3214" mass="351747" checksum="2312149321ED0AA1" modified="2025-10-08" version="1">MGSPPSTERCSDGVPPERLRAKNFYHENGEMHGRTNVRQKSYLLDEDVRHFDTSFFHINPKEAADMDPQQRILLETVYEAFEAAGWPLSAVDGSQTSVYVGEMTDDYTNIQARDPDYLGSHAATGASRAILSNPAQGLQRGEATQAVVAGTNLLLDTFFYIMESSMHMLSPESRCRMWDKDADGYARGEGCAVLVIKTLERAIRDGDHIECVIRGTGVNSDGHTKGITMPSPLSQTSLIRQTYQAAGLDPLTDRCQYFECHGTGTQAGDVVECQAIRDAFFPEDQRTTAADDDILYCGSIKTVLGHLEGCAGLAGVIKASLAIQNKMIPPNMHFNQLNPKLEPFYQNLEVPTALLPWPETNGGPCRASVNSFGFGGTNAHAILESYDSSGSGTTSPLSSYVDAGGSSVCPSPARGVRSGPFVFSAKTQTSLVAWLKRFLTYLRENPTVDLDSLSHTLHARRTVHSHRVAIPMALHRKDLAQKLEDQINALGTSGADLELDQHHHPQRTSIRDCWAYSPAKYVFLPNCLFFVSIILGAQSARMGYALLQHCGLFKEFIVECERHLKSIPHPPTWSLVEELSANNTNSRVSEAEFSQPLCTAIQIGLVDLLHASGVMFSDVVGHSSGEIGAAYAAGLLTRKDAMGIAYYRGHVAHLARGKAGEAGRMMAAAMSFDTAAAICAEKRFAGRINVAASNSPLSVTLSGSEDAIDEMKSHLDDIDVQARMLKVDVAYHSHHMLACTERYSALLKQLDIQVQTPAPTQACRWFSSVRTGTNILDNAPGAGLEGRYWLDNMVQPVLFSQAVTLAVQANAATKVTAVIEVGPHPALKGPVNQTLKQATDYSAQYAGCLGRDKDAIETFSEVLTTMWHLAPRSLDLAGWRKALGGMLADAPLALKDLPSYAWDHTQIHWRESRVGRNYRLGEHLPHDILGRLWSDSQYEQTWRNILQLHEMPWVTGHVFQGQVLFPATGYLCLAVDAAKAFLKARPIKLVEVRNLEIPTALVIGEGDEVEIQFSIRSSVLPEKAEPGSVLEAEFVCYSFPDQQNASKTCHGKLLIHVGDSDPADLPPSFISSVELTPLNVDRFYHAASEIGFGYQGPFRALKSINRCWGHAKAVASWHREDLDVDCTLQPAVLDIALQTGLSTFISTAEGSMPSAFLPVGIRRVLINPNEAFSAAVDGSLETEMESYMTSPGMGKMMETDINVNFRAGARNHPCAVQMEGVRFQAIAEPQPSEDRNIIAKITWDVDPAYGLTDRHVVPQDQRRQSPPPMYSAEEYERVALFHLQSFSQKLKRDSPSGDLDSRHQALICYVDATVALIREDKHAIPLKEWLHDDADTIANLVRRYPNDAGMTELTKSNGVNGHSSTCCAQQTARLMLQISHKFPRTRILEISSGINSNTTATVLGAIGDAYEYYTCTGASEAIVNALKEKNNFASTKDFAFKVLDLESDVASQGFETAAYDVIIAPNGLRASPDFAETAVKLRHLLRPGGFLVATELTGDSLRPTASMMGSDTWWLGPGPGAATCKARPGLGLGEWDKLLVRSGFSGIDCALYDRPDTKLHGFSVFVTQAMDERLEILRDPLTSLDLIAPAPLVLIGGETSQVSQLVRSSFDHVDRSRLPPDACVISFQDLDRPFFSSPPAAHELKNFNEVVESARNILWVTARRLVDDPYANIMIGIGRALRIEVPHVNFHFLDFDEGEPWDIQAVVAKFLRLVYSSSHGVTDGILWADDPEVVIRNAQPMVARVVQDQVANQIYNAKRRKVTKLVGPAEPIEISQDAGFSQPTLICSRPVVPLQDQWPVHVELSVAIHSRRDGPRCFLCYGFLKDQDDAAVLTLSKVESSVVIVAKDIEFTSKATGGCDAEALVNIASLLIAASVVAKMPSSGTTLVCGASEGLADRITFVALAAGRKVTFIAITTTIMPKERDGWVYVHPKSTAYSVNQIISLDSIANVLDLSQKDADVISPWLPPGCTIQTFDVNALSQHSVQEALDANRKSQGDRTWKNLEPVLVNVDEISQARSSNPGHLSTVTNWKRDKPVAAIVSGLEPTALLSSNKTYFLVGMASELGQSLTYFMIRGGARHIVLSSRNPKEDQQWIHALRRAGVNIRLVKMDVTIRSQVRDTVAELRRTMPAIGGVTNAALVLDPGVFANLSAESIARQLRPKVTGTANLDDEFRTDALDFFMTFGSLLTVCGNAGQPIYHAGNAYMASLVQNRRRRGLAASVLNFGMLVDVGYVARSDRAADSHVEEWLRSETRTPLSEADFHHVILQGIVEGKPGSGSGEVIMGLETFFDQGQSSRPAWADSALCSHMQWKQKLEAATTAEQATQPITELLSKKIEAMIHVSLHSIHLDEPMLHLGIDSINAIGIRKWFRETLGVDVSMLKILGRDSVASILKTVAEQYVAKKPAQSGVSKPKATTAAAPKPAKAAASAAHTASPKMPGRSTDPVRPNGHRETNDVTDRTVRSGQSTEQASQQVSNQSFEQASEQLSYAQAGFYYLSTISESPTSFNITVKFSISGHLNAEKFCRAFQKSMLHHDAFRSAFVVDPESSDVRQCVTTSSNFQITQVQSSKDTAEEDSSKAFSQTQTHEYALAKGDALQATLVCHDAQWHTLVVGFHNIAIDAISVNYLLVDVDRAYQFRPLTPNPTSYLDFTRQQTEDVRAGRMDQSIAFWKGLLDPLPEALPLLPMAKVKTREIPCAYAHHRVEKEVSSDLVQRVKQICQANGATLVHFYLAAMQVVLGRLLSVDDMCIGIMHTGRNPDSEFAQTVGHLANILPVRFRGFMQKSLPDILANTSRTLLDCLDNANVPFAVISDRVRGGAGDSGQPLIRVAYNYRAGEIDSMPMGKCTVTRGEVDFTTLYDLTIDVLQSESNGTVLTVRCSDDFYNLSTAEFITDTFVNLLESMVGAPSALVKDLGLFNKAQLHQGTIVARGPDTQHEWPQDLSARFEQVAAEFPDSAAVKDSHETVTYRQLRQRVGTYAGILLEAKVKPGARVAVLCEPSVDLYATMLAVFHIGAVFVPLDVSVPPQRRKAMMDACKPDVLAFHAPTATRASEEQVDVRLLLNMTSLAQEWSHDPERTVMDPRADSYIVFTSGSTGVPKGIRLHQQGMMNYAAYTSQAYGFGQVNVLQQTSIGFDLAFGQIYNAFTNGGTLIAASVEARGDPDALSRLIHDEKVEYTLATPSEYSLLLNYASDVLKRCDAWRCAHTAGEVLPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXA0</accession>
    <name>A0ABR1VXA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutathione hydrolase</fullName>
            <ecNumber evidence="1">2.3.2.2</ecNumber>
            <ecNumber evidence="1">3.4.19.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyltranspeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="1"/>
    <dbReference type="EC" id="3.4.19.13" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666812.1">
        <property type="nucleotide sequence ID" value="XM_066814850.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047910"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686">
        <property type="entry name" value="GAMMA GLUTAMYL TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686:SF62">
        <property type="entry name" value="GLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045085645" description="Glutathione hydrolase" evidence="3">
        <location>
            <begin position="22"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="542"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="556"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU368068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="567" mass="60353" checksum="DBB2EC306F626EF0" modified="2025-10-08" version="1">MRRGTPSQLLTAAHLLGSVLGAVCAPSPPSYSNRGSIPKLGAVASESSVCSRIGVDLLEAGGNAADALVGTVFCVGVVGMMHSGIGGGGFMLVRASDGTYEFIDFREVAPAAAFEDMYKNNTDASLYGGLASGVPGELRGLEYLHTNYGVLPWAQVMAPAIKVARDGFRVTEDLVRYMNTVSGDGKFFTEDPSWAIDFAPHGYRVKLNETMTRKRYADTLEVIAKEGPDAFYSGAIAKATIAALQAANGTMTTDDLTNYTVALRKPSNITYRGYKLTACGAPAGGSVALSALKIVESYDGFGDDSQLNLTTHRLDEAIRFAYGERTNLGDPSFLEGILEYQDSMLSDATTAEIHAKISDTTSHNVSYYDPKGIESLETPGTSYVGTADKSGLAISLTTTINTLFGSQVMVPETGVIMNNEMNDFSIPASSNAFGYIPSPANYIRPGKRPLSSISPTIVESADGKLYLVVGSAGGSRIITATIQNVHNVLDRNMTTPWPWRSRACTTSSCPTRSRSSTRLGHNVTWVAPGQSTAQALRMLPNGTFSRRPASRDRPTRAGSRSSAGRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYH5</accession>
    <name>A0ABR1VYH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pectate lyase</fullName>
            <ecNumber evidence="10">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_009637</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="10"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665914.1">
        <property type="nucleotide sequence ID" value="XM_066813952.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047012"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8074974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="244" mass="25077" checksum="2F67CAC41031B937" modified="2025-10-08" version="1">MKYSAVLAAFGASAAIAGPAFEKRAAFPVPASKGSVTLKAPQAVSGTFDGGMKTYGRGVKCTGQAEGGDSDAVFLLEEGATLKNAIIGADQIEGVHCKGSCTIENVWWTKVCEDALSLKGDGNANVIGGGAQGAEDKVIQHNGLGTVTIDGFTAMDFGKLYRSCGNCKTMGLRNVNVKNVKAYNGKVLVGINSNKGDVATITSTCATSVKQTCVEFEGTTPGHEPKEIGSGPSDHCKFTALKAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8I7</accession>
    <name>A0ABR1W8I7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667273.1">
        <property type="nucleotide sequence ID" value="XM_066811931.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044991"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="439" mass="44396" checksum="E547A1C13D45375F" modified="2025-10-08" version="1">MMPPKPPPDVEEGVGTADETAGVASVALAVGTTEVTSGAAEDAAGVASVALAEEEGRRALVRPPIIPPKPPDPVDVGAAEETAVVASVAFAVGTTEVASEAGEETAEVTSGAAEDTAGVASVALAEEEGRRALVRPPIIPPKPPDPVDVGAAEETAVVASVAFAVGTTEVASEAGEETAEVTSEAGEEAAEVKSVAAEEAAEVASVALAVGAGRTALVTSETISPKSLVNPGSRPPLSDEEVAAGALEVGVTKPVGAMTTPLEDAATVGLAALEEPAAADEPLLAVETADSASFVDVVDPRPIFNKPLDGRSMRGELPEDPAAEDPAAEDPAALDSVFPDGLGVATTPVIVVEGETNTGVVRVIVWLSLSPEFDPELEASSFDDPRPFDRLAMRSPRLSDESRFVVSDFSEVVLSGVEAAEGALVMVMLVNCRFTCRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8S9</accession>
    <name>A0ABR1W8S9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pathogen-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667361.1">
        <property type="nucleotide sequence ID" value="XM_066812019.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045079"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053218">
        <property type="entry name" value="Pathogen-related_defense"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31723:SF10">
        <property type="entry name" value="PATHOGEN-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31723">
        <property type="entry name" value="PATHOGENESIS-RELATED FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="30314" checksum="B3529D923BA7D1C6" modified="2025-10-08" version="1">MAGLPDYMTDPNAVLGDVDAEWRHGQPPDYSKTRKVFEQNTVANITPGMATMTSTPVLTPARARAIGKQTSHQPGSLPDLVQNLVKNWEIEASFKTNLRDWRTVDPDAYTFAVNGGPPQPAEHMLKVGTYNAIIGAPNAWYSPRRSDLASSHKTFKRMMPTFAWEVLEVYGGPPVVAFKWRHWGEMKEDYVSLDDNGEKITAKAHGGPIDIQGVTVAHLNEKFQVTKLETWFDPVEMFRQIAPEGSALSQQSSAALAGGGRGVSCYGGQPRCIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9B9</accession>
    <name>A0ABR1W9B9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fad fmn-dependent oxygenase oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007933</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667590.1">
        <property type="nucleotide sequence ID" value="XM_066812248.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045308"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF9">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="27"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="480" mass="54544" checksum="BF857EFC0B46322A" modified="2025-10-08" version="1">MDAHHELASRLSPSASLCYPGSEGFDASNLRFTKYELQPGCIEDVVETVKYATGKNIPFSPRAGHHAVTSTMRHLQNGILIDMRTLNGLAFDEEGQTVTVGGGVITDNFVKFIHKVGMEVSVMGVALGAGLGRLQGKYGFLHDNMVSCKLVLADGFIVVASEKENANLFWALRGAGHNFGIAVEATFRVHKQSNRGTHYTWDLEYELEQCDEVFSTLNEVTETMPKDLAIFVLWMRKSTEGKQVRALHTLSSQPTDDSRMKHMILVNLVWSGPEAEADPWIARFETIKPVLHSGKVTVEWPELPWTTYKGYNKFLSMPEVWTVAPYKMMSAACVKKFDLKTTREFFESVKAKNIEFAGKGTFGAMFECLPHHRVREIPDDATAFPWRTSSDHFLMLMATPMKLEDREEFEKHLDGWKSRFIETSGYGELHQYVNYGNTTSTMKDPPEALYGEPWRLEKLRSLKKRYDPNNVFRWYQPLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9J3</accession>
    <name>A0ABR1W9J3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Clathrin/coatomer adaptor adaptin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007992</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667649.1">
        <property type="nucleotide sequence ID" value="XM_066812307.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045367"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026740">
        <property type="entry name" value="AP3_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037096">
        <property type="entry name" value="AP3_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="7">
        <location>
            <begin position="39"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="553"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="681"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="682"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="731"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="748"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="796"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="807" mass="88762" checksum="1FF96864E80ABF40" modified="2025-10-08" version="1">MESISRISSLLESARELTLDAAQAARSSTRTATKSLPTAHLKKLLDSRNEREIQDGLRRVTAMMYRGQRTLPFFSSVVKNVASPNLEIKKLVYIYLIHHAEQEPDLALLSINTIQKSLSDGNPQVRALALRTMSGIRVPVISQIVSLAIKKGAGDMSPLVRRAAALAIPKCYRLEPACLPQLLEYLSGLLGDKQYFVAGAAVSAFLEICPERLDLIHKHYRSLVKKVVDMDEWSQLAMLRLMTVYARKCFPRRTRNAKTQDTSGDLQDFYGDGRTAAPGGSEETVVLDPDLALLLNTIKPLLQSRNSGVVLAVARCYANIGTPEYTKMAVGPLVALMRSAQDIEQVALYNIVSVCLVHPASFVKYASHFLVRATDSAPVWELKLEILTLIFPHSPLHTKSLILNELEHFSRGTNKALVREAVRAIGRCAQTDPATAPRCMRLLLGQITSLDGTLAAESLTVIRHLIQQDPEAHMGTVVRLAKNLDSATDPQARATIIWLVGEFAGLNGEDNIAADVLRILLREFTDESEIAKRQIVLLAAKVYLHHINREAEKLQQEQQQKQQEKLASEENGDDEDRPQSPAPAVQMPSEDHPIAKLWSYVLLLVRYDTSYDLRDRTRLYKALLEVPQLATLMLLAPKPAPQALSPSETRKGLLLGSSALVLAGGGGVHGLRGYEPLPAWVEEGREPDPKLRGAQEGGRPEYGEGLSRGSIPASQRLDETSPSSSFRGMEAAGAGKSNGSGAKTLDDWLAEDEGDSEEEEEEESGEEEEEESGEEYETDDGGEEEGGDDDEDDSEGEKGELQRFLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9V3</accession>
    <name>A0ABR1W9V3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667741.1">
        <property type="nucleotide sequence ID" value="XM_066812399.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045459"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025363">
        <property type="entry name" value="DUF4267"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14087">
        <property type="entry name" value="DUF4267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="159" mass="17454" checksum="72113D61EAFE6E5A" modified="2025-10-08" version="1">MDFKQILSESLNKPSIIPPGYVLGSCFLGLGIMGIISPAQAELAFPVRRDEEKDEEEPSNVHPAARGLTITRVLRAHLYSKAGRDLVFGLSFFALQYQGSMRAVVALEGLVTIVGFVDGFAVWKYGAEDAKPLAWSYWTWSLSILAIAGARLYFLPSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAL9</accession>
    <name>A0ABR1WAL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GEgh 16 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666980.1">
        <property type="nucleotide sequence ID" value="XM_066811638.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044698"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF3">
        <property type="entry name" value="GEGH 16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045044619" description="GEgh 16 protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="39217" checksum="E5A0A7DF123D3B06" modified="2025-10-08" version="1">MRSTTAVLSAFLAVAHGQNIISAKGNLGTSKGLQVDPNDPFDMNIIKTSEISANVVNQCGRTVVGNMDVGANTEVALTKGEVTKVTKGSKVQVQISQDNAQMSGGPYTCDLDDQSNAKGATGQIKLQQVNGNGGGNGGGNNGGNGGNGGNGGGNKFGGGGGGNPFGGQGGGGGNPFGGQGNKFGGGGGGGRFRMRQLEVRHETHSRIGARANTMTLTVSMPNDLQCKGSSAGNVCTVRCINKQEVGGCFAVQQTDVKALPGSNAPGNIQTAQTKDGIETQVLQNKQDFSAAASAIANAQGSSDDDQQDQTQGAAVAKAVLAQQQKTGIVKSNAGNQANNGNNNNNNGGNNNNGGNGGGNGGNGGGNKFGGNGGGNGGNKFGGAGGAGGFGGFGGGRGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBR0</accession>
    <name>A0ABR1WBR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008758</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668415.1">
        <property type="nucleotide sequence ID" value="XM_066813073.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046133"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF157">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="31"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="330" mass="36632" checksum="2B3BDDC069839492" modified="2025-10-08" version="1">MAFEQGYWSTPEHVITAAIGLSILDITFLTLRFIARHKQRQPLKVDDWILIPAALLTLGISIAMVYGVSRKAIGYPYEIPPEAQGNALFVTTEQISLAGQIQWTFYLLLPLALGCTKMSFLFFYKRVFAIDRTGATNVLLVGMIVLVSMWMTGFFLTSLFQCKLEFGAAWESPIAQIQHCISQPKQALALTVTDFITDIVIISIPIPLIWRLHLKPAKKVAVTAVFLLGAVTVAVSLFRLVFTARLVQFGFDPNSDATLLITSVQYWGIVESGVAVFAACLPTLAVLVKGRSWDPVANIARSLVNFSNSSLRRLRTKTSRRNIPDTYSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC19</accession>
    <name>A0ABR1WC19_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668530.1">
        <property type="nucleotide sequence ID" value="XM_066813188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046248"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="95" mass="10520" checksum="8CEB912457C5359B" modified="2025-10-08" version="1">MSPPPPPRPGITMRRELFRPGPQVPNTHPVRTLESDDPLEISECFGELLGRLQLGTTKRVGITTTKPQTQTQTTRRKRTPTPPPKEGRGTPTLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCW0</accession>
    <name>A0ABR1WCW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667775.1">
        <property type="nucleotide sequence ID" value="XM_066812433.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045493"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="210" mass="22645" checksum="1FDA215AE02017DD" modified="2025-10-08" version="1">MGKLANTTDRPSHETTCTDNAGYTDDRTVPNSANSSTGTAASSSANMTTKAHPEMIIRYASEGFAEQGPPVPKGVPSEADASQAAVVAARSRAKRAGKTLKILLEKKRAMGEAIAHMQLPGDGERELESFVSAFDRLIWQHTVIEAGKHHRQQVPNGPSTLSTLRTTYGVLDKLVDNGKIRRGKDMEIDENGWPKLCDDGGFSPNQQENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WD84</accession>
    <name>A0ABR1WD84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Regulatory P domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667895.1">
        <property type="nucleotide sequence ID" value="XM_066812553.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045613"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF3">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045201086" description="Regulatory P domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="52093" checksum="1BE017737589DD72" modified="2025-10-08" version="1">MKSQTFLAAVVAAWQSTAMGKEIPNPARSERYDSGEVHEGIMALKHAQWAAREQMGIFEVTQYKSYAGEAPVPCVDGFAEVVPGDKNNTFACSNVDFYDFKSHADLGSAKGQGSSSWGWTSPEGREYVAVAQADGAAFAEITKAGKLVYLGRLPQYTTAQPSLWRELRGYKNYIVIGSEAVDHGVQIFDMSKLVDVDPASPVTFTNGKDLTGYWNGLPIGRTHNIVINEEKEYAVAVGAQPRTSACASGLIFIDLTDPSNPVSPGCAPGDGYVHDAQCIVYRGLDEKYNGKDICFGYNEDTLTIYDVTDKNTTNIISRTGYEGSAFTHQGWVFQDNWLVMDDEYDEYDKTDGGVGKPITYFWDIKSLEAPKLTGFYRHSRKGIDHNQFVVGNFAYQSNYGQGLSILDISSIPTDPTGGSVTEAGFFDIYPEDDEAEGGGQIEFVGSWSHYPFFKSGYILINTMERGAFVVKRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL65</accession>
    <name>A0ABR1WL65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668748.1">
        <property type="nucleotide sequence ID" value="XM_066809825.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042885"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF11">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04355)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="56"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="144" mass="15174" checksum="4DF1A937659F939E" modified="2025-10-08" version="1">MGSSQGDEIKTHIEALVARQLERSPIYALTLSAVRIVSATRGRVVARTVLGKNHMNSVSATIVDWAGGMAIATWDLRDKTGVSVDIHVRYLASAKEGEEIEIAATADKVGGSVGFTSVVISKVVDGEAGPVVASGTHTKYVKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLQ6</accession>
    <name>A0ABR1WLQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668984.1">
        <property type="nucleotide sequence ID" value="XM_066810061.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043121"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050977">
        <property type="entry name" value="Fungal_Meroterpenoid_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39598:SF1">
        <property type="entry name" value="AUSTINOID BIOSYNTHESIS CLUSTERS PROTEIN F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39598">
        <property type="entry name" value="AUSTINOL SYNTHESIS PROTEIN F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="16803" checksum="04636A52EF27DA71" modified="2025-10-08" version="1">MSSPAQVQADTLNRFLDAWKTQDVGTTIELWSEDFKQRLLPYSLGAAAKSRAEAAIIYPILTSNLSNWKLEIKQIVHDTTRGTAAVYATSSADTPLPDEKWATDFAVFVSFTEDGTKINKLDEMVDSAFYRSFFPKFQQYLAETRGAPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM10</accession>
    <name>A0ABR1WM10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Succinyl-CoA:3-ketoacid-coenzyme A transferase</fullName>
            <ecNumber evidence="3">2.8.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005793</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate</text>
            <dbReference type="Rhea" id="RHEA:24564"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:35973"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.8.3.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Ketone metabolism; succinyl-CoA degradation; acetoacetyl-CoA from succinyl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 3-oxoacid CoA-transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.5" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669031.1">
        <property type="nucleotide sequence ID" value="XM_066810108.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043168"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.10">
        <property type="entry name" value="Glutaconate Coenzyme A-transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012792">
        <property type="entry name" value="3-oxoacid_CoA-transf_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014388">
        <property type="entry name" value="3-oxoacid_CoA-transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004164">
        <property type="entry name" value="CoA_transf_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02429">
        <property type="entry name" value="pcaI_scoA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="KETOACID-COENZYME A TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707:SF23">
        <property type="entry name" value="SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000858">
        <property type="entry name" value="SCOT-t"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01274">
        <property type="entry name" value="COA_TRANSF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="519" mass="55433" checksum="E12975546A0296E8" modified="2025-10-08" version="1">MPSAALCMRTLRAYSKYGSNHALVLAKAFSASARRAEINKVYPSATEALKDMRSNTTLLCGGFGLCGVPDTLINEVLAKPEITGLTAVSNNAGTDTSGLGQLLKSKQIKKMVASYIGENKTFESMYLTGQVELELTPQGTLAERCAAGGKGIPAFYTPAAFGTVVQTGDLPLKNKADGTPDQYSYPKDVKVFNGKSYLLEESIAGDYAFVKAYKADKLGNVQFRLAANNFNGAMGRNAKMTIVEAEHIVEPGEIPPEAVHLPGIYVKRVIQSTTDKNIEKYTWAKDENDPDAKKALGSGDTAAKRERIVRRAAKEFKNGMYANLGIGMPMLAPSFVGPEVEVQLQSENGILGLGPYPQKGKEDADLINAGKETVTLKPGAAVFGSEESFGMIRSGRINLTILGAMQVSGTGDLANWMLPGKVKGFGGAMDLVSNPSATKVVVTMEHTDKKGTPKIVKQCAFPLTGRACVSRIITELGVFDVDFAHGLTLIEIADGVTVEEIKAKTEAPFTVADDLKPML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM29</accession>
    <name>A0ABR1WM29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_005839</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669077.1">
        <property type="nucleotide sequence ID" value="XM_066810154.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043214"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758:SF4">
        <property type="entry name" value="MITOFERRIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758">
        <property type="entry name" value="MITOFERRIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="21"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="118"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="211"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8084568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="311" mass="33758" checksum="7CBF7A33CB989179" modified="2025-10-08" version="1">MAQPTAEPVDDYDYESLPPNFSLAQNMAAGAFAGIAEHTVMYPIDAIKTRMQIINPSPNAVYKGMVEGTMRIATGEGVLKLWRGMSSVVVGAGPAHAVYFATYEAVKHAMGGNRAGVHHPLAAATSGACATIASDAFMNPFDVIKQRMQIQNSSKMYRSMADCARYVYRNEGLSAFYVSYPTTLSMTVPFTALQFLAYESISTTMNPEKKYDPFTHCTAGAVAGGFAAALTTPMDVIKTMLQTRGSATDPELRAVNSFMAGCRLLYQREGIRGFFKGVKPRVVTTMPSTAICWSAYEASKAYFIRRNTPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMD0</accession>
    <name>A0ABR1WMD0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_005971</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669209.1">
        <property type="nucleotide sequence ID" value="XM_066810286.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043346"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047010920" evidence="9">
        <location>
            <begin position="22"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="10">
        <location>
            <begin position="35"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8084700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="192" mass="19345" checksum="45F2874345F4D198" modified="2025-10-08" version="1">MARLTAALVLFGIACTTLVTATPEPFNQEESNRNSDCDNGCFFGSFPGGSCTNDAACMCTQQKYREKYFCCMAQKCAPSVLPDSIDRQNSECGARNMPFTFDAEAACGIKLAASSSAVMSLSAATSTTASGSQSTSAAPKVTAATSSSGAAPAGSHASAGASPTPALNSAPMGLAVWNGAAALVVGSGLLLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNV8</accession>
    <name>A0ABR1WNV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="14">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_005998</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="14"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669236.1">
        <property type="nucleotide sequence ID" value="XM_066810313.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043373"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="18">
        <location>
            <begin position="351"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="28"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8084727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="679" mass="77415" checksum="74035AE6B325817A" modified="2025-10-08" version="1">MAVVEREETEATAILGSLDAMSLGYPRCRSIRGTQGPQQEEEEAKAKTTPRGGLHRSGGRCPSVRKERRRRHESGDEDREARRARRRREAQTDDERGESSRRKERRRYEAVTDHETDHEAPRKPRKRREAYTDDEADHYRYDPPRKSRRPQRAMDSEVDERSSYEQRHVSKDRRKKGRIVSGAIVEEGRAMPGIVAAVALVVLIIIIVVAVVVSKKNSGLDDHKKSNLNDIPKDSIPPASRGTYLDPFTWADTSDFNLTFTKETVGDLPIMGLFTEWDDSASANDKVPALDKPWGDYTKKPARGVNLGGWLSLEPFITPSLFNYDSRLNIVDEGSLCSHLGPKTCAATLEKHYANFVTEQTIKDIVDAGLDHVRIPYSYWAVITYDDDPYVFRTSWRYLLRAIEWCRKYGLRVKLDLHALPGSQNGWNHSGRLGDIRWLNGTDGTMNRQRSLDVHDRLSKFFAQDRYKNVIAFYGLANEPRMVNLPADAVVSWTSDAYRVVRGNGFPNQIVFGDGFMGLANWQGKLQGLDGLVLDVHQYVIFNRDQIVYTHQKKVQYACDGWTEQTQLSMNRATGFGPTMFGEWSQADTDCAKHVTNANADPSRYSDTYKKFLKMFAEAQMVSFEKGLGWWYWTWDTEDAPLWSYKKGLAAGILPAKAYDKEFKCDTDVPDFAGLPETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPF3</accession>
    <name>A0ABR1WPF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006677</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669915.1">
        <property type="nucleotide sequence ID" value="XM_066810992.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044052"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="35"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="471" mass="50091" checksum="F7FDD44E44F8ECE9" modified="2025-10-08" version="1">MIPEFTELRERITRGKVLTPGDEGYEASLERWSTTCIKQAAVVIKPADAQEASLAVKFATAHAIPLVVRGGGHSPSGSSAIEGGMVIDLGLLRSVSVNTTDRTTSTAPSGRRGFATVGGTVSHTGVGGLILGGGFGQLTGRHGLSIDVLVGCEVVLANGDTVTASADQNSDLFWALRGAGHSFGVVTSFTSRIFPQGMAWGGVLVLPIGALPDLVSFINAFCEKNDGDQAMMPMLACHPATLEPCVATTMFFNGPKEAAEAFYAPLLRLEGAIMNTTAVIPYPVANTFPNPKAPPGKRYLFSGANFVYPLDLKMVQEVSDMFHAALAPEGNREMRAGSMVAFELIPHDKVSAVDTAATAFAGRDGQAMNMIINVAWQSPDKDDEAKRICSELTHYLKDRGWRGDEAGDRGGTYLNYLIPATEADKAYTRADRVFGPNIERLRELKVKWDPSNVFNKAVNLLPASGKANGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPF5</accession>
    <name>A0ABR1WPF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668874.1">
        <property type="nucleotide sequence ID" value="XM_066809951.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043011"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34706">
        <property type="entry name" value="SLR1338 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34706:SF1">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="44"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="285" mass="31338" checksum="E953AE2299E089D4" modified="2025-10-08" version="1">MEQDAAAGSPEPPYPLGEGIPVPELTRHHVTNDKDPFAFLEVFDTVFLIDDSESMQQHWHEVIALICAVVPICCERDPNGIDLYFVNHRPRSYSSLFSSVEKSGYRGIGLAVGSPLQSDNVAGILHQVKPRGRARLGARLGDILAKYVADYSYLTRLHKDRHCKRPMNLIVVTDGHIEDSLYGHLAAAARELDRVHAPAYQAGVQLFQIGHDPRISAGLKVDDDEMHKREGTRDMVDTTTWSGRPGVLSAEGVLKVVLGAVSRSLDRSTVTKSGLLAAEVRQQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPT1</accession>
    <name>A0ABR1WPT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ataxin-10 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006328</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a role in the regulation of cytokinesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ataxin-10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669566.1">
        <property type="nucleotide sequence ID" value="XM_066810643.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043703"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051374">
        <property type="entry name" value="Ataxin-10/CTR86_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019156">
        <property type="entry name" value="Ataxin-10_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255:SF0">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09759">
        <property type="entry name" value="Atx10homo_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ataxin-10" evidence="7">
        <location>
            <begin position="635"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="247"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="561"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="569"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="588"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8085057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="784" mass="87399" checksum="CD39F84761C1640C" modified="2025-10-08" version="1">MYPLKEALQMLIKLMHIARNLLVTTEPEIPQDLSAAINFDHEVYEAICLCVNVTSKGIDGEMPEDDASRVKLNEITELYKKVLVTSLQQAHNWIAKNDRNKMTFWYRVLIESPDVDNNPGPKIDTNLCWTAICREYFEAQDEQQKNHWLPPDWNLAWNYTPQEMWAWKPDIYDEAIKVISQWNPEEPDKYEQDRAYGHVSHELDSWWESTRMPNARDSSLSMYPLDLVPERIKQCEANLMQRYAGPEHVEQEEAAKSPQIDEDPSEKYPEYNPEIRTQPTTNYAPEYDEYEEDPDDDDSYGEGPMTGLLTEVPNILDPKQIEALHMIVKSCILESAGTGPTRFGESLQHARCRLLLATDCGKNLLREMLVFIAVWEKDEQSLIFQISAQIVQSIHFNSLIPYAWNALRSPKDIISPAQTVLLRLITFLSRTTFHPSKEYNPVAPPADAPDWQPGEDLKFAKMLNFLYGIFRSRIVPECVALMQIQGDVRKGDLDPADFPVDNWDLERAKDGLVQYLDFLYTIADIHPLRQHLVDYVTVYELLKLLEGLDIGVEKIPFAGGRPAPPVPATAPASAASGEGQAGSSGHPANPPPPPPPPPPLSEPAYEFPWSGIKGQVLSILAALLQPPPGHTSPGNPTVQLQIVQHNGIVALLNCCLYDDNNRFCRERVQLCLKWLMDGSPDASAFLQNLVSANPGPMVRPPAAGGEAGAGTANGTTQTVRIDGVPGEVRVQVRSSSAPAGEAAGGSGATAGGCLRHTGASWRLKSYGARRAFLKGDAHQIICFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ38</accession>
    <name>A0ABR1WQ38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_006403</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669641.1">
        <property type="nucleotide sequence ID" value="XM_066810718.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043778"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022099">
        <property type="entry name" value="DUF3638"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022105">
        <property type="entry name" value="DUF3645"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046541">
        <property type="entry name" value="DUF6606"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051346">
        <property type="entry name" value="OTU_Deubiquitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367:SF34">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367">
        <property type="entry name" value="UBIQUITIN THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12340">
        <property type="entry name" value="DUF3638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12359">
        <property type="entry name" value="DUF3645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20255">
        <property type="entry name" value="DUF6606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUF6606" evidence="10">
        <location>
            <begin position="14"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3638" evidence="8">
        <location>
            <begin position="2063"/>
            <end position="2292"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3645" evidence="9">
        <location>
            <begin position="2419"/>
            <end position="2447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8085132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="3156" mass="356646" checksum="225071D42CC6D2C9" modified="2025-10-08" version="1">MDIDVDNRSALLYLIDHVFLPPKLPQEDDFTFPKNRALLKNILDALHQFGRHVAHDHVSDIQRAVGLVSTMIDCRPRLNLDERKVGDALAGLTPEGVLCFQLTGQNFGILITRQDQTVFFEQFELLASNNAVMSCQGRLGRTFPSTCISMQYSQYNASGFTSALAHCLAKLDSSTHSSCRPKSQKQGERDEERDTIDPRLSGLLSGFLRGLGAEANVVQIKKCSREEVLWDDARLPWHRSATWFSVRVTLQLIWSRKHKAPSSTPLFKSFIAFFLSTCVAQAQTLSIPDHLLYCMLAKLNRRCLKLSQLPYFENNKPNWLSCCSSVYTGAKDYLEKHWTKTQDSDKRPLPLEKLKTLSFTADSVLGIPSFKKYTSEVKLEAATSSGPGGSHSSYPFSRTEGVMPPDIGSIQNHRCLTLADFETWIATNLSSWLENNIDKQNTCQNLSQMIVSYHSIASDIYRQNPFNLSVMWLSILELWVACDKTATQQVPLLTDYDTEIPTKLLEPLLLPSLPLMKRLHDVESYLQHRQARAQPGYPSIFGKFGHPHSFAVRFYDGSSFHQAVHQEILNAAESDRIDKFAELAHEKTVYERLQSAHTRASHEKHLIPRYNHTLREEVLEEVCTNNCSKCDLETRMGNMYISVHEWPLPTNKYEANAVIFELQVPDFITAWRSVTLKLLTDMLVLKDCPSRGFENVPYGTSHYPELHKHQQDLTSRLRILSAVKPFKVAHYRQQTVPEATQQSICTPHGCQYEYYDWDDSSSFARSCSNLKAMKPTIPPSCSFANLSMFPLTHWIGGYTHSSNEIISQQSSCPANMALESFKAFGHMRSGHRLQWRNVLAQLAMPSIDFNQVETALVTFQSINEAGPCADEHSNVLRDAHSLLNDRAFALSLLQALRAAFHRVHKNWECEVSFLIYSTICTRLLVTSRDQDIREECGDFLSTIRSTTRDWALFLLARRDKTDNEHEAEDFNRRAIGMSLACCSTFFVGIDEIGVIFGPRDSVTTYLEISAIIHDHGQAYDQQNQINLRGLEAPWTTHSKEAESLSPFMVISLQSWHRVCYLFQPFLADRICQDHWCIDNAISSFWAAYAPGMEWTSGEKGYRHVMTSGCCPSPGIPNIPISYDLFEGSLLVNGRPLSRLPSEYCRSPTYQRLFGNQSLKVSPSTEFGMQFTATRLKEGAIIHFTMKNEHLIVRSCKDGSKWDFIPPEVLTGDFPESLIAPYSHWLNIGSGVLEFRHHKHPWCSSGAIWRANTSSATITLKKDDKVLIDCRSNTAVLIGGILETLENPSYITIVLDKISSEVEVDLPRYDLTFTLKPGSIDLRCNKYPGMCIDRTQSVGSLIGLKNKLVLRSVTEAHGRKALVIPFGTPQVRGDQDCHPVTAILPTETKGTEESYSGIARRTHHYYEIDTILGRVVDNGSLRSKLLLCHLHATTSHCLIDPLTSRTGTEESLRILRSAAVASFSRLDIADAEMLFSIAQLSPTRSFYPEHLMEMQNVKWNGSLHPLAQNDEIRRIAISLLQQGESCEAYFLPARSFRLPEDSNKKLVDRAMIRNSVFRVDEFGAEFFTHSHDCVYQSRDTIKSPSTRKRERRLCHVTKLLLFQDEYLTEALPDADALVNRIYSILGSEVEDASGSSDVPYGELDIHWLGHPAQAIGKNWRGIHRYLTKVKSLQPKFKLMTFFGALIFAPQADFGFIQLLVKLVNCPDVRYHQHPQHAVFTLGDGRGYEGFQILQCLERHKRHFHGTPESSRSRRHNESVHDFDRRRVRAWESKVDSLKRTFESAIREQYPSTRPVAPISSEMGIYFNVDRVMSDVHGLFQSWIRNHSLHDYLKSIAGIVVKLPQSPIPPTFCAFSFQPLPMSSQTAHVTSSRLFTSNAPELACKSLDTLEDVCFQSTRAEGRDQLSHQTSRPLIESLRGIVKEPHDARYLDELRMSFDNYRVIERGVPYSQLTLDSDTLSKRLQTNLRLCLVQVQSFEAIILASFDSHRTSVMPNSRLFFPRLSPVFILQQLNKNHWPNLPGPWRSCITNYALALTHLQRAQRMLGLVENKPDLIKEANNIGHSWNLEEFPESLLMEVESKIIIRDVQEEVAASMRESKGNRALQLNMGEGKSSVIVQIVAAYLADGERLVRVIVAKPQSKQMQHMLVTKLGGLLDRRVFFLPFSRSIAMNPAKVAHIQAQFETCRKAGGVLLVQPEELLSFKLMGLEHVGAPRTPLATFSNSMTDTGHRLIESQKYLDTLSRDIIDESDENFSVKFELVYTIGSQRPTEMSPDRWLVIQNVLTYIARYAPDVSKSHPESIQLHTVQRGQFAVLRFLKEEAGRLLLRKVARHICDYGCQGLPMSHQGSANRELIFSYITQLDVDQDTIRCVGDEKTGFSDTARNVLLLLRGLFAHGVLAFAFGQKRWRVNYGLTIRSPPTMLAVPYRAKDSPAPRSEFSHPDVVIVLTCLSYYYGGLSDDEMDTAFEHLERSDQSTTVYGEWVAGSPSLEPAFRQLEGINRKDRSQCLDKVFPALGRTKAVVDYYLAKVVFPKECMEFPSKLSASGWDLAKPRPQAVTGFSGTCDSKYVLPTDISHVDLPSQLHTNATVLSNLLRPENTVKLLGPDLSSEALLAAVVGNDTPIQVILDVGALIVDLENHEVARKWLEMTPHSGKKAAIFLSKEDEILVMDRNGFVEPFLTSSFVANTDACLVFLDEAHTRGIDLKLPDHYRAATMMGPKLTKDRLVQACMRMRKLGKGQSIILFVPMEIQQKINALIPRQNTSIQVSDVLCWSISETWADTRRSVPPWALQGLRHQRQEAIWGSKIEHGDVNTVSQDDLQDYFEDEAMSLEHRYCPAVANAREGLQGYLLDLHASERRPQIELIQAKCEQFGVTNLASATLQEEQERELAPEVEQERQVEKPSTAKPLEHLLHPDVLRMINTGELLRKSGTAFEGAFDSLRTISVNSLPDLGGFGQGLLVTTDFSRTVELDERSSPDAFQRGVQWILTFRNTPALHVMVILSPFEANALLPLIEKSPHVLLHVYLPRSNLTLPTLQHLRLQITPVPPPHWEAPADLTMRLNLFAGQLYFNSFEEYKSMCAYLGLSYIPNEGNAAASIDGFVGRAQYPDCLFTHSPTTFLQFVMANVRRDRQDVSRTHVGCMLAGEILTEADFQNASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQM4</accession>
    <name>A0ABR1WQM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670337.1">
        <property type="nucleotide sequence ID" value="XM_066811414.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044474"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="496" mass="55698" checksum="A7173C25DC7062D6" modified="2025-10-08" version="1">MGPHQARSKGQQYATNFSTGNCDNRQLTSSSYPAEYAFEYDPDGIISQQTQTMNGRPMADDAMFGPQPSDTPFDFVTSNQSQWQSHPGPESYYPSPPQIFPVGDDYSNLAYPVDPLTNQDRNSAATGTQQPGLLPLGSGASNSTYRPIAPAPPVPQIPHHHQQHAANVAAAAPIGSNWQHVQQQQQQQQRTNSSGRPQQHQIPIRLDISSFPNEVVFDEHGRTFQAYRQDGYYLPNDPQEQDRLDFQHEVYKTLTEGRLYLAPLQKPPRSVLDLGTGTGIWANEPQVLGTDLTMIQPTHRPLPPNVSYIKEDAEEDEWSVPLGFDFIHARELLHVDQGPYEVYKHLAPGGWIEIQDVRVSFHSYDGTSQGSALERHCQLFGEGLTRLGRDITALDRYRTMIADVGFVESSIREHIIPVPCSDWPEGAANRHYRWAGLFQAVNILQVVNCVTNKVIQVAGVSEGENRRLAADVERELVSKRVHGYWPYHVIYAQKPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRP7</accession>
    <name>A0ABR1WRP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669879.1">
        <property type="nucleotide sequence ID" value="XM_066810956.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044016"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="116" mass="12611" checksum="8627A056DA02527F" modified="2025-10-08" version="1">MVKERRQTDDNEIDKLFSIIMKPTPGVSETCHQYDDPITNLNQSGDKSVTTGFQDAVIAPTMESPSFKRTASELATAIIGCIVGAPTVAADLVSIVLGWDVTKTKLGVWFSHRRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WSC2</accession>
    <name>A0ABR1WSC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007149</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670387.1">
        <property type="nucleotide sequence ID" value="XM_066811464.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044524"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF12">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_6G13830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="264" mass="27855" checksum="AE3E7867F6E54565" modified="2025-10-08" version="1">MVLPQHSKASAPVLSHFDLTGKTAIVTGGCRGIGLEAARGLAEAGAKVAITYTSTDPAEADRIAALLSKDAGVPVKAYKCDVKSPDEVRAAVEQVTRDLGGGRLDICVANAGIAAHIPALEYGEGAWREMLDVNFHGAFWTAQAAARIFAEQAKRGGDGRASIIFTSSVSGILVNVPQQQAAYNASKAAVTHLAKSLAVEWVDFARVNCISPGFIATDMISAHPEERIKQWFDMIPGKRMCDAAELKGAYVFLASEASSYMTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWQ4</accession>
    <name>A0ABR1WWQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670485.1">
        <property type="nucleotide sequence ID" value="XM_066806867.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039927"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="153" mass="16962" checksum="7F91F5EF80DFA390" modified="2025-10-08" version="1">MPSYLETIARASIDEDVAEAGKCCNVSCRTTQHLFESGTRHRAVAYTRPESKVRDSSEKSGDSEVSALLTEKGADYPTSFRCNVGWELNGRDSFIESVDDKNNYKHGHGLAKYLRAFVESGDLPSRFVVDLCRGEHWTIIPTTLSSGGVQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWU0</accession>
    <name>A0ABR1WWU0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670530.1">
        <property type="nucleotide sequence ID" value="XM_066806912.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039972"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="87" mass="9581" checksum="581BF905DF52589F" modified="2025-10-08" version="1">MGTDGTGSGSATWMRKVESAGLEFAKPPRDKHEKPPSDCAIAGCQATRVPRPLQKQSGKMEANRRYDVSSTERDDFPAAYREYDALC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXS9</accession>
    <name>A0ABR1WXS9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670853.1">
        <property type="nucleotide sequence ID" value="XM_066807235.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040295"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="225" mass="24850" checksum="F810224CF5D183B7" modified="2025-10-08" version="1">MSVYNTCYKKRPSTRSSRHTVQEDQFTRQRPPHFIQENIPSGQTAGSLNEPTDELAQELESMAMSGRRETGAHPIGSARTSTSTSNRTPSGRRPGIAQCALMQAQDPAKYSLTPETLEVFNHEQGGHEHYPNFSNWCSGTYNPGAQPYAIADAATTGPGYSTYATRTARSQATDTSWVVVSTPDERQDRIAENISGAGALFYDIPAEPAWNDYDTMYDVYGRTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXX7</accession>
    <name>A0ABR1WXX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glycosyltransferase family 71</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_002965</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MNN1/MNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670898.1">
        <property type="nucleotide sequence ID" value="XM_066807280.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040340"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646:SF1">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="192" mass="21628" checksum="E82094BA9DED000A" modified="2025-10-08" version="1">MRLRWQVFVKENILPYRVTNHAPFVGRGIVVVGDHPKSLKHVRVLVRSLRNLGSVLPVELHHWAGELNAKTKLDLIRELGVNFTINDLFRPHNLYFSKTQYNDISHINFQLKTAAILNTRLAEPLLLDSDNVPANLDPAVLWDSATYQEYGPGNGPRWSAPCCHDHVPRWTRNPSNGSTGTASLSTTPIPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY03</accession>
    <name>A0ABR1WY03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1295 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670926.1">
        <property type="nucleotide sequence ID" value="XM_066807308.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040368"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF23">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="40465" checksum="405651C9C14A80E9" modified="2025-10-08" version="1">MGVPLLQTLEECADYSKTVEPYLLQLYELPARLAQSASSSDALLGIYKSTNPLVSGFAFSIFLGSIFLVASEFNRNYSQVDRLWSLLPTIYNAHFAAWAHLNKLPTQRVDIILLWSAIWSARLTFNYWRKGGYTIGSEDYRWEIIRKQVHPALFFIFNVTFISFIQSVLLFMLAAPTYIILLTTQHEPDLTTADVVFTSVQLLLVLSEWFSDQEQWDYQSAKQEYRESAVVPQGYTQQELERGFITTGLWAYSRHPNFAAEQTIWFMLYQWSCYASKTLYNWTGLGALFLVMLFQGSTWLTELISARKYPEYKHYQRQVGAHIPGFTAYKAPAPKVIRTSELAKKHAAKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY12</accession>
    <name>A0ABR1WY12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670938.1">
        <property type="nucleotide sequence ID" value="XM_066807320.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040380"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038753">
        <property type="entry name" value="NFKBIL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263">
        <property type="entry name" value="I-KAPPA-B-LIKE PROTEIN IKBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="56"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="23927" checksum="7228759D539F77D1" modified="2025-10-08" version="1">MADDEGAAYWEGVYGQPIHVYANARPSAEGGGELEQMTDDEYAAYVRQKMWEKTHQGLLEERARREEAKRAKDDKEAEARRLTRQMEESLRRGEERRRRRSWREKYEDWPVARSSSSSSSSSDGSRAEISPETVRDFFVNGLDPIEIGESVFLAKLKEERFRWHPDKIQQRLGAGFDENVRRDVTAVFQIIDKLWSDIRAKAKAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYA2</accession>
    <name>A0ABR1WYA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <ecNumber evidence="3 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003085</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="3 7"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671018.1">
        <property type="nucleotide sequence ID" value="XM_066807400.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040460"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="entry name" value="Lumazine/riboflavin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058:SF0">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE DMRL SYNTHASE LUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="Lumazine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="199" mass="20663" checksum="4A0DD1B9E24FFA71" modified="2025-10-08" version="1">MASSLKGPTPQQHDGSALRIGIVHARWNSTIIEPLLKGTKDKLLACGVKEKNIVVESVPGSWELPIAVKSMYSASQVQASSAGGGSAGDLLASSTTDLTALSSSTASAPFDAIIAIGVLIKGETMHFEYISDAVSHGLMRTQLDLGIPVIFGVLTVLSDEQAKARAGLLSGSHNHGEDWGSAAVELGVKRGAWAQGKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYH1</accession>
    <name>A0ABR1WYH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GLCD beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003172</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671105.1">
        <property type="nucleotide sequence ID" value="XM_066807487.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040547"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11387">
        <property type="entry name" value="bHLHzip_USF_MITF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051732">
        <property type="entry name" value="USF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117:SF3">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="6">
        <location>
            <begin position="274"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="122"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="192"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="473"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="492"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="510" mass="54886" checksum="35BD2D33DB883668" modified="2025-10-08" version="1">MAHFGFNQFGGGQGSSNGSIDPRAMSGIHDLNGGSNGYSTGSAMIADSDLLDMSPQEPNQSLGDHGQDFSNGMSDINMGFSQNMYPSHINGYSNTPDGDPVHSPWASSFNAAQHFRQMQQPFGHSLQSPNSFAGSPLANDGSNDGEGSFLNAKPRPRLSQAQAQAMQRNSSSNARSPLGANAVMAGLNAGSLESPNFGAQPIRTPGGHHEKSPSGQWMNTPKSLQSSYPGSGLSSPLQHGYSNPQFMAQAGTSMPARVNGAPTNLQSQEAKRKRRRESHNAVERRRRDNINERIQDLSRLVPTHRLEDDKVKKLIQNGTPLSPTLTGMSQPNQATSGLAGPGAKRATAIGAGNITTGLPLEDKDKGPNKGDILNGSVSWMRDLMWMLQLKLQQQEELINTITEMGGSAPFELTDDEKRMQTELMEALSKFENEPAPFSYSRFNGSGLRVPHHTDYRGDSLNGAPGIDTLSISPGDTADLTGDLNNTDQFWNDPDDDVKDEDEYGGMDLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYN2</accession>
    <name>A0ABR1WYN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003194</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671127.1">
        <property type="nucleotide sequence ID" value="XM_066807509.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040569"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF11">
        <property type="entry name" value="RNA-BINDING PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="257"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="9"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="334"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="212"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="406" mass="41390" checksum="1434D8A95DA74CAD" modified="2025-10-08" version="1">MSCLELVVAPSTPTPSKLSGFKPAFSSATPTVQQPHHTPSPGVKAGPYAPPPTAYSSAPSYPGASAPNYGAAPSYSSYAAPPGAGAMSGRGAGGYGAPHASSYQRYPQAGGYGAQPTYYGAAADTTSSYGAAPQIRNPFPVPQAQPAAAAGAGGASAGAGGAGDYDPDMAAQIAQWQSAYVPEAKDAAASGAPGAGLGRSGAVSAAATYAAEPSRPAAEPTAAATTQADGKKKTVVRAGGGQKWTDDSLLEWDPSHLRLFVGNLAGETTDESLFKAFSRWKSLQKARVIRDKVTSKSKGFGFVSFSDPDEFFAAAKEMNGKYIQSHPVVIRKSTTEIKPQTVKDKHGGKWNKNKNRNNRNQNQNRGGNGGGAGGARENSFEPSLGPAPSGVTKPGQKTKGGLKLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYT5</accession>
    <name>A0ABR1WYT5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD-dependent monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003288</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671221.1">
        <property type="nucleotide sequence ID" value="XM_066807603.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040663"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF10">
        <property type="entry name" value="2-MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="10"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="7">
        <location>
            <begin position="434"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="603" mass="66442" checksum="DFDEA85A6145B678" modified="2025-10-08" version="1">MPHAEPSTDHDVLIVGGGSAGLCAGIWLARCGIDFKILERRDGPMRQGQADGVQCRTVEIFESFGIEGLLLREAYHVLELAFWAQSDNVGLDEPEAAAARNGGGDGVGVAERVGEQVETGGIARTHYAPDTEPGISHMPHVILNQARMNGIMTEEMTRAAGRDMVEYGVEVIDVSVDQEQAKDPGAYCVSVTAKADGATRHMRAKYVIGCDGAHSTVRKSLGFKMIGDSHDALWGVMDVYPRTNFPDIRKKVLINSEAGNMVVIPREGDYLVRFYMELPNYAGAAADITLADLHEKARLIYRPYKMEIANTKWWSAYSIGQRQADHFTAAHRVFLTGDACHTHSPKAGQGMNVSLQDGYNLGWKLSAVLRGRAQPELLETYVSERQKVAADLIEFDRYFTQLFSTAYRKEHGITPEHFHEQFVRSGRYTAGQAIKYDESAIVCLGGAKESATRLEVGMRFPSAQVVRLCDAKAMQLVRALPSDSSWHIVVFAGDIRDGEVSARLDEVSRELSDIMHEFVPEGVGPDSILHFVLVLSGRRTEIELQQIPEVFTPITGKLQLKCLLNVFVDDQSYSSGHGHAYESYGVKPQVGALVVIRPDQCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZB5</accession>
    <name>A0ABR1WZB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">homocitrate synthase</fullName>
            <ecNumber evidence="5">2.3.3.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_003457</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>acetyl-CoA + 2-oxoglutarate + H2O = (2R)-homocitrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12929"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58884"/>
            <dbReference type="EC" id="2.3.3.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:12930"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-alpha-aminoadipate from 2-oxoglutarate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.14" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671390.1">
        <property type="nucleotide sequence ID" value="XM_066807772.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040832"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07948">
        <property type="entry name" value="DRE_TIM_HCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02222">
        <property type="entry name" value="Homocitr_synth_fung_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048253">
        <property type="entry name" value="DRE_TIM_HCS_fun_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011872">
        <property type="entry name" value="Homocitrate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054691">
        <property type="entry name" value="LeuA/HCS_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02146">
        <property type="entry name" value="LysS_fung_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF48">
        <property type="entry name" value="HOMOCITRATE SYNTHASE, CYTOSOLIC ISOZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22617">
        <property type="entry name" value="HCS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="15">
        <location>
            <begin position="55"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="436"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8088496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="476" mass="52089" checksum="8BC5030ABEF1BAFD" modified="2025-10-08" version="1">MCPTPDAAPATNGRANGNDTSDPSHPGFTGIATQRTQRSSPYQPVGDFLSNVSRFKIIESTLREGEQFANAFFDTETKIQIARALDDFGVDYIELTSPAASEQSRKDCEAICKLGLKAKILTHVRCHMDDARMAVETGVDGLDVVIGTSSYLREHSHGKDMTYIINTAIEVIEFVKSKGLEIRFSSEDSFRSNLVDLLSVYSAVDKVGVTRVGIADTVGCASPRQVYDLVRTLRGVVNCDIETHFHDDTSCAVANAYCALEAGATHVDTSVLGIGERNGITTLGGLMARMMVADRDYVMSKYKLHKLKDLENLVADAVQINIPFNNPITGFCAFTHKAGIHAKAILNNPTTYEILKPEDYGLSRYVHFASRLTGWNAIKSRVEQLGLTMTDAQVKLCTQKVKAMADVRPLAIDDADSVIRTFHLNLTADQEKPLLPNMTSEEQAKFEKAEKELAGEPEQKSLDNTVAQETNGGIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZD0</accession>
    <name>A0ABR1WZD0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671368.1">
        <property type="nucleotide sequence ID" value="XM_066807750.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040810"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF156">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EFM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="267" mass="29471" checksum="6D940B15B967C02D" modified="2025-10-08" version="1">MGSIAVEQVPFSSELVEHRSTYEISQSASTKIPLVIVETACRAENLTLTTWSSSVVISNTLHKLDIPLDQLRADAPQETKTATHHGYKILELGAGTGLTGLSAACIWGSRALLTDLPTIVPGLQANIDANSSLFQAQGAGAGCGTLDWNAPSDLFIYDPASSSEVKVGITEDNKFPIVMAADTMYTEDHPELLTRTIATCLSRSKDARAITCWPQRVCYLEPLREFWRLMEERGLEVAQEGQEYADFEGLDDEPLHEWSVWRWKDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X050</accession>
    <name>A0ABR1X050_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-1-3-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671682.1">
        <property type="nucleotide sequence ID" value="XM_066808064.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041124"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021047">
        <property type="entry name" value="Mannosyltransferase_CMT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144:SF5">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE CMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11735">
        <property type="entry name" value="CAP59_mtransfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045987437" evidence="1">
        <location>
            <begin position="30"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="429" mass="48130" checksum="05E7B0E8D9706DD0" modified="2025-10-08" version="1">MSVMSRRSLNLASCLIFLALVLCVLYAQQRKPSPLSIHDLYIEHEEATEFEPGETRILSQAETTAYVKSILDPKETHTSRLQCPLPDPRRYGHLKSRYARKSPVHYHFALNIRQCLNLLPQLLGSVVEAIRFLGPEQCALSIIEGNSKNGTPEVLAALRRELGKLMGDRVRIVLGDNIDPVSLGSPGGARFSRLAELRNMALQPLVQHAERYAEEATVIFVNDVAICTEDILELVHQRRALRADMTCAMDWVVGDDGRSLFYDSYIARAANGDLFFDIPPETGSFGHGVDGLFWNEPVARARLEAHLPFQVFSCWNGAVSFAARPILERKLAFRTAREDLGECYGGEPQLFCKDMAFQGYGKIAVVPSVNLEYSIEKGETLKRLKGFVSSLVEDDGTKDAITWQPPPDQVKCMPTFNNQYWRPWNDTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0B0</accession>
    <name>A0ABR1X0B0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Glycoside hydrolase family 132 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_003792</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SUN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671725.1">
        <property type="nucleotide sequence ID" value="XM_066808107.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041167"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051526">
        <property type="entry name" value="Beta-Glucosidase_SUN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005556">
        <property type="entry name" value="SUN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31316">
        <property type="entry name" value="BETA-GLUCOSIDASE-LIKE PROTEIN NCA3, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31316:SF0">
        <property type="entry name" value="SECRETED BETA-GLUCOSIDASE SIM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03856">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0134">Cell wall</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045319043" evidence="12">
        <location>
            <begin position="18"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="113"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8088831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="429" mass="45480" checksum="020EDB21FA0A5D8E" modified="2025-10-08" version="1">MKTTILNLALAATLASAQPHNHGHGRFHQKRVGASPVENVAKRGDVVTTVVAATETAYVMGDKVVTPEEAKAGIDKGLFIVVGESTPTFVPPPPPSPTPTTEKKIMAQFFQKPEPTTTSTPTPEPTPTSSTPPPPAKSSSSGSSGSGGSGLHADFPDGELPCEWESLEKYGAVSVPWAGIKGFTAVQKVPTFKAGMKIANIITAIKGEGCEDDSFCSYACPAGYVKTQWPVEQGLTGQSVGGLHCLNGKLYMTQPEKKTLCEENAGFVTIKNSLSKGVATCRTDYPGTENMIVPTWADGGATAMLANIKSADYYTWEGKDTTLQYYINPSGVAVEDACVWTSPTNPDSAGNWAPTNLGVGQSRDGNTYLSIFPNAPTSFAKLDFNIRITGDVTEKCVLENGVYYTNGKETKDGCTTAYKEGANVVVEYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0S2</accession>
    <name>A0ABR1X0S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM7</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MCM7</name>
        <name evidence="13" type="ORF">PG997_003926</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671859.1">
        <property type="nucleotide sequence ID" value="XM_066808241.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041301"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008050">
        <property type="entry name" value="MCM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24901">
        <property type="entry name" value="WHD_MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01663">
        <property type="entry name" value="MCMPROTEIN7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="12">
        <location>
            <begin position="395"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8088965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="808" mass="90024" checksum="3486F2F54306D984" modified="2025-10-08" version="1">MALLQYRKVVDYDAQQAAFEDFLDKYKTSPQDTIAHAIGQISIDEDDLSDEYDFMDEDDDAAQHDRRRKKAAQRQQPKHKYVEMMQQLADRTIDEVLIDLDDVASYEEANDENLKLVESIEANTKHYVEILSRAIDKKMPAPTSGTTFKDDVLDVLMERRQGRNQELAQMAEASTDPELLARTFPAQLTRRYTLIFKPRTSTSDKPVKALAVRQVRGEHLGHLITVRGISTRVSDVKPIVQVGAYSCDRCGCEIFQPINDKSYAPLTSCPSEECTKNQAKGQLFQSTRASKFLPFQEVKIQEMAEQVPIGQIPRTLTVMCYGSTVRKINPGDVVDITGIFLPTPYTGFQAMKAGLLTDTYVEAHHIVQHKKAYDEMIIDDRLLRRITKFSQSGAVYDMLAKSIAPEIFGHLDVKKALLLLLVGGVTKEVGDGMRIRGDINICLMGDPGVAKSQLLKYISKVAPRGVYTSGRGSSGVGLTAAVMRDPVTDEMVLEGGALVLADNGICCIDEFDKMDDNDRTAIHEVMEQQTISISKAGISTTLNARTSILAAANPIYGRYNPRISPVENINLPAALLSRFDVLFLLLDTPYPKHPDLYASNGDADGNGEAANVVFTPHEVRAYVAQARTYRPTVPESVTEYLTKTYVRLRKAQKAAEAKGQNWAHTTPRTLLGVVRLAQALARLRFASVVSQDDVDEALRLVEASKESLAAHEGPRRRGRDANTRIMEEVKKLLDTGACRPDDEEYDEEDGSIELSLRKVRERVLAKGFTEDQWLTALDEYTSLDVWQTAGNGTRLLFINTGNGDEEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0W9</accession>
    <name>A0ABR1X0W9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003981</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671914.1">
        <property type="nucleotide sequence ID" value="XM_066808296.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041356"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="52"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="509" mass="54527" checksum="89D5DC4ABFB0F84E" modified="2025-10-08" version="1">MAPIEVKQYINGEFVSSDDNKTFDIFSPYSGDCVARGMLIDANMVREVADLFAVSEATTVDVDKAVAAAQAALPAWKALSPQQRGKPLAKLAQMITDADAELAQLDALSLGRPVSTYFDGYYAATHFRYFSEAAYPVGTSSLNTPGFMNISVRQPYGVCAAIIPWNAPLVFLSKKLAPALAAGNTMVLKTSEKAPLSSDRVAAMLGEAGFPPGVVNIVHGHGPVSGQAISSHMQIRALSFTGSVRTGRAIQTAAAASNFKHLTFELGGKSPALVFADADLDHAARDTQHSIFFHSGQTCMANSRIYVQKSAAAAFVDKFNALAAARKLGDPSQQETTSGPQADKAQYETVMRYVEEGKKTGQMVETGASLPAKNGDLFVQPVVFLQQPEDSKIMKEEVFGPVVCINTFETEEEALKIANDTEYGLYAAVYTKDLDRAMRVAKGLESGMVGVNCTSPTGAWDMPFGGYKQSGVGRESFLLSMDDWLEQKAVFIRVEGLDEAGTGNTTLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X128</accession>
    <name>A0ABR1X128_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="domain">
        <text evidence="4">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672033.1">
        <property type="nucleotide sequence ID" value="XM_066808415.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041475"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009117">
        <property type="entry name" value="ANX14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01813">
        <property type="entry name" value="ANNEXINFUNGI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0041">Annexin</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="87"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="453" mass="50116" checksum="35EF6A2DB607DE6A" modified="2025-10-08" version="1">MSYNQYPGYGAPPPGGPPQPYPPQGYPPQQQGGYYPPPTGQPPYGAPPPPQSPYGAPPPGQGQYGAPPPQPYSPRLPPPQQQQGGYYPPPAVQPPPPYGVPPPSHSPYGPPPGQYGAPPPQPPPPQHYGPPTPPSLGYGPPQIIQWNADFDAQALHRAMKGFGTNEQLLIDVLHNKDPLQIEALKPAYFRVDGRKTLEGAIRDETSSYFQKGLIAIVQGPLLHDCHLLYDAMKGLGTNEKVLNDVLLGRSNADIQAIKGKFQQVFNVSLESMIKGDLSLKTERHFLIVLRATRAEDSAPLIPQEIDRDVDAIYDATEGMVGTDEMKVCSILSTRNDNHIRAIAHTYEQKYRRRLDDVIRKEFSGHMEDALLFQLRHAADKYMHAAALLEDSMAGLGTKDHLLVSRVIRYHWSPEMMANVKGAYKQRYKESLYKRIKGETSGDYRRLMLACVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1G1</accession>
    <name>A0ABR1X1G1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glycosylphosphatidylinositol anchor biosynthesis protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004192</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672125.1">
        <property type="nucleotide sequence ID" value="XM_066808507.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041567"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009580">
        <property type="entry name" value="GPI_biosynthesis_protein_Pig-F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06699">
        <property type="entry name" value="PIG-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="26223" checksum="34B95364D80EE7EF" modified="2025-10-08" version="1">MSAPSGKTVAAGSGQKTASADDEALCRAIPTLPSPLAQALRHVHPALLLSLFYLRFGALVRDPVSALISALPAVAVLQVAYAVICLPAAGSSAAVQPAKKLRPGEKRKPVADANAPNITSTVVVALGLSMFATFGLQIFFVLFGAPLLTHIPQTALCSLHLSLLGLFPLFYTHGISTSDWLEILGARAPFDEAFGGLVGGCVGAWAGAVPIPLDWDREWQKWPITILCGVYGGYVAGKFIGGTLAFGKKFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1I6</accession>
    <name>A0ABR1X1I6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">60S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672144.1">
        <property type="nucleotide sequence ID" value="XM_066808526.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041586"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_eL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_eL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF31">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL22A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="14127" checksum="60206E3DE7C77380" modified="2025-10-08" version="1">MAPQTSKKAGKGKTTTKKFIINAQQPASDKIFDTAAFEKFLQDKIKVDGRVGNLGDNVVIKQAGEGKIEIIAHNELSGRYLKYLTKKFLKKMQLRDWLRVVSTSKGVYELKFFNVVNDEADEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1X3</accession>
    <name>A0ABR1X1X3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672315.1">
        <property type="nucleotide sequence ID" value="XM_066808697.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041757"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="418" mass="46043" checksum="A9705288C988991B" modified="2025-10-08" version="1">MGLPLFIAPVESDITSKPSTKSSADPAHARSPIRRSERRRQLHETREHRLRLLAALQANDDSLTQPESTGRASGTASPSTDALRSSRHSPSAYDDILGLVRDHRDRRDRREALRSRPPHPDTNIQHEESFLRADGPEPRYVTWSNESTPDLASTNWGQVVNLSNGGSLLYRSRLREANASSANSPALYTVQPHDYPPSASRLTQRLRESNSSGAGTRASRSQVPDPGEYLDEYRRRRRDAQSDAPRVSSRPRAWRSVRYVDGLGDRDRSLSPEDSNVWDTLQSTLTPDPQPPSVGSSFASTTASVGTSQTTASSANTSVTHPDETAELPCEPVADHSESDGEDEEHRTGPSRRTIALSSRSYADVVALPPARGGPERLEWLSDMQRIVQGLASRQDIPDQWWAAAGLSRSFVMGDDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X395</accession>
    <name>A0ABR1X395_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004783</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672716.1">
        <property type="nucleotide sequence ID" value="XM_066809098.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042158"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF40">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="183"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="675"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="679"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="699"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="755"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="890" mass="97384" checksum="98541140ACCAA527" modified="2025-10-08" version="1">MEQAGLGSEAEAGPNPKAPAGLKPIRRRNRMINSCLECRKRKLKCSKTSPSCVNCLKAGRDCLYIGPRLDEASQLRLAEIKEKQGSLERQLERDVAKSAAATTQRHALGQRILADEIGDEDADEERYLESTPLAALDLTYEDDADGADDMIDLGIQIGRMRITERIGGLSRPRISEEISAGLSGQYRSHGGTPRSPFGVPLPSGPSPALGPPTGLDSMSDGGASDISMPDFLRPGAQYIAPTSGLFFSQVIEQPSLSTFLPCREYADRFLRQYFLSVHPIATCAQRASLEETYAAFWNVVNEGYFEPRASTQAIVFAALFSGAVAMDENDAVRELGGFAKENWVHSLKMGTETALSKANFLRTTKMETMQAFIIYMLPLCRAEVSRAHSVLVGAAVRMAECMGLHRDGEAYGLTPLETHVRRLVWHQLCFLDIRTCEAQGPKPVIRREDYDTKLPVNCNEDQLTHAVVPPEPADHWTTNTLALIRFEINEMMRIIWLDRRRLEVRKISLTDIENFRRRMSEKYDHLLDVAQPAQRYAKCVMSLLTYRLHAMVLHPYHSNAAHPMPAQLSSLLVSSGIVIVEHAIQLETNPLFRPWAWYLGAYFQYQIALLLATEVYYRPGSRDADRIWTCLDYAKGVHLLSEIQGKTAVYMRLRKMRGPTNTARAALAQNVVAGTAKQPSTSTPFAAAATTAGYHQTRQQQQIQQAQPPQQQQQHAASVSSLFLHGSNGPKAEVADRHTPPVPQPQHAGAVPMHHQPPPPPQPQPPMEFAGVSDGQVLYSLPPNHESPGSSDTSSVGHAQTLNAMGGVEGSNAAAAAAAAAGAPLAGTALPTTTVGGSIMDTIDWDTMTMLFPQDPHTGAFSIQGYNDPNSLLWMGLIDGGGGAEAPVMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3J2</accession>
    <name>A0ABR1X3J2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Structural maintenance of chromosomes protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004938</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMC family. SMC5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672871.1">
        <property type="nucleotide sequence ID" value="XM_066809253.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042313"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="6">
        <location>
            <begin position="89"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="445"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="650"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="247"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="370"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="682"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="811"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="907"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="656"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1118" mass="128247" checksum="B46C869D08072FE2" modified="2025-10-08" version="1">MPSTTSHRRSRSVYEDEEGIQSPAPESSKRRRQGRRRLSVENDFDEDDSDRDESNESHTQTNGSSSFRVNGAPNPNGQHATEEYHPGAIVRVMVEDFVTYEHAEFFPGPNLNMVIGPNGTGKSSLVCAICLGLGFHPRNLGRAGHVGEFVKHGKDYAVIEVELQANPNQRSNPVVRVQISREDNGRKWWLNGRESTQKAVHGLTKEMRIQIDNLCQFLPQDKVAEFAGLTPIDLLHETLRAAAPEKMIEEQSQLKTLHQEHKKLKANVDTSSETLKQLESRQQAQQADVDRLKERDAITARIEEWKKTRICAQYEVAKHAHSAAKAAKNEAIKRLNNLERACGPALEAVNSKQDYKTKIELVVSDREKRLKNAEARSAQSILEIEKQSNDIVQKKREITAEKSSFAKRREEIRELRLKITGLEAKRKQEPPAFVAGEWNQKIREKEHRQREIAEEKRQANTHKADTQRQGTAVHAEIKQLRKEIEDLNSQEGQLVSYLRRIDPHVAKGWEWLQDHRDEFEEEVFGPPMLNCSLKDGRYSDLVQSMLAKNDFLCFITQTRKDHQKLSDQFYKEMRLRVTIKTCVNKIEEFRPPMSADEARQLGIDGFAIDYIDGPSPVLATLCSDKRLHASGVALREASAEQFKQLLKGRKYRNGQRDQPASSTKQVRPGQFWTDQPVDNAEKADLQNKLEAKDEEKQELIKEFEAAKARVAKLEDKDKEVMEEIAQLRSDKSKLQTAYTHWSALPEKIDTEKASLKERQDSFAECRSRIAQLTSQLDDLCCEKAQAVIRHKALVENIRNAHLALLDARIRLVEATSDIQGLKDRNRNITQDLDNTKAEINNHKAATIAAKEEAVRVSNLFKDFESDEHDIEHYRKQATGKTPEDIDQEIEAEKANFDLIQPVDQQVLRQYEKRNREIQDYTNRKEDQARKLEKVGDQIQKLMRSWEPSVDQLVSRINDAFSYNFQQISCAGEVGVHKEEDFDQWAIEIKVKFRENETLQQLNQHRQSGGERAVSTIFYLMALQSMAQAPFRVVDEINQGMDPRNERMVHERMVEIACREHTSQYFLITPKLLTGLRYDPRMRVLCIASGEHVPPEARQLDFKKLVSLQRAATALKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3L4</accession>
    <name>A0ABR1X3L4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672906.1">
        <property type="nucleotide sequence ID" value="XM_066809288.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042348"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="342" mass="37669" checksum="16F78C99532ECDBE" modified="2025-10-08" version="1">MPPQLLPASAAAFAPRASSVNVVLGSKVEPWLTQTLKRINRVKRPLNSVPQHQRCLTETLSSPNAIWTLTSMMLPKGPDADLRQDSNPLVEALFNYQLLHIEAYIVHVDMVLRNEVAFKLTPDSIEALIEYHKDIHIVNAKAGTYDWSEKEQQAKKLHEDFIQAINKFVFRTHVSALEGLEEEGAGELLCGKSEEVKNNINGLMKSLLPPPPRIVDVVRQPPLLPSSPAGANMWAQNTPSPAAPVDAWRVLPSSPSCTSTSADSSNTPIWANMSMNEIQIPSPPTPNYSQPFTTAGFFYSSPMVTAPIPALPLPSMLAPQCGVNIGYGGFNWDRYQEYTTTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3T6</accession>
    <name>A0ABR1X3T6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fatty acid synthase CEM1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004978</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672911.1">
        <property type="nucleotide sequence ID" value="XM_066809293.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042353"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021150">
        <property type="entry name" value="Ubiq_cyt_c_chap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007129">
        <property type="entry name" value="Ubiqinol_cyt_c_chaperone_CPB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184:SF1">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03981">
        <property type="entry name" value="Ubiq_cyt_C_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome c chaperone" evidence="3">
        <location>
            <begin position="142"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8090017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="344" mass="38045" checksum="884CFB24FCDFD7FE" modified="2025-10-08" version="1">MACRSCRSHIGQLARQARITSNSAEASAASSIVAASRLAANPSQRSQRQPAQQQQQQQRRGFSSAPRSQASMLPDFIKNAAGHLLQSSTQPYQVHRATEIIYKTCASQATYTISEEDKRNGTVQKAEDGVEIGVGKTMWHTEFGLPATFSTWSQVTMLHMYLVCARLRNLDKDAARSWQQQLVDHYFFDAEERMDLTHGITSRGVRQRYLKDLFVTWRGLLAAYDEGVVRGDAVLASAVWRNIFSASADVDVRSVAAVVSWMRLCLKMLDQMPDEALFAQASAAFKWPAKNELNVVDRPVRELEGLLPNAPAAVAATATNVKAEEPTATEKESIANMQRKLGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7G1</accession>
    <name>A0ABR1X7G1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673391.1">
        <property type="nucleotide sequence ID" value="XM_066806095.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039155"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="347" mass="38700" checksum="5CD0A4C6790DD96F" modified="2025-10-08" version="1">MGSSSNASTSTDPLFTKELPPPPESESSGSLATTPLADHQGHPAHVASSAHAGADADAADGAVITGAESFWPSVDTDDSDTPPDVAPGSPRSSKESFTLHPFEIQQWSWTWVRRLGYGLWSVLGVDLEPIPPQSEVPNCQFQVMNITDAWKFQLQFDFVHLRMLGELPPLSAIDSLYEHLAPGGWAEFTEWVQVLQCPNHSVEGSAFERWDRAYRRGKLQIRETGHVSVPLQRHVEEGRVPTSSRRKYAVPLNAWPNSKSLQRIGSMTATNYLSVIEILSRDLFVHVLGWTAQESDALISQVRTDLQEPNIHSFYTLYIRFSIPFPYQETLADRYKSLTVYAQKPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8B9</accession>
    <name>A0ABR1X8B9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673641.1">
        <property type="nucleotide sequence ID" value="XM_066806345.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039405"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="224" mass="24733" checksum="2E8C0BBDB7B60F3A" modified="2025-10-08" version="1">MAAKNVNSNPKNGYLILSNEVVLDIISYLPEDVNQLRLVNRATNALVGPPRCMVLDKPCQSALLGAVRNAMNASPDSVSNLRYVMSHSKCYPCRYGRSTASETALRGEDDLDSPLHYACESWDSEGVINLLVAAGHDLNLECGWPRQRTPLFRACEVGNYATARNLLRAGADPRRGAYANWGSTEPLPLIHRAVLPPPQPPIVNIPTAPRLERDKEQMLLYGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9W2</accession>
    <name>A0ABR1X9W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000145</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674233.1">
        <property type="nucleotide sequence ID" value="XM_066804460.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037520"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF124">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="73"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="251"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8093460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="359" mass="39532" checksum="082020C752BB2CDA" modified="2025-10-08" version="1">MPTTYGVETFLPPPPGYDINFIHHQRRGDAEIYWVTGVGNVLMALFVGQRLYTKVAFSKGLHLDDGLLILAWTVYIANLFHLFCGAAAKLSLCVYYLRLAMSPLHRRFVSATMTILVSYTFVVLCCMVFSCSPISKAWQVNSTGTCLDRSSLHIVAAVMDTATGVMLLALLVPMVYGLQMPLRRRLTAVGIVAVGLLSVEVNLFVIVPTMLTLYEFCHEAKRRWNGKRRRLSLESLPMTTSSASTMTLKSTYMTDCSGSPPKEDRRDRNQGKKAHFFGTAGNHHHHHGTENELSSAIQGIKGKNGSQISIGLCDETELREQQRSASALSMRNGGGSGEVDSEKGILMTTTVTVLHEKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA42</accession>
    <name>A0ABR1XA42_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674283.1">
        <property type="nucleotide sequence ID" value="XM_066804510.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037570"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="170" mass="19221" checksum="3C691D37841E5D58" modified="2025-10-08" version="1">MALSDTDKCDKEFEAFRKEVIIGGLVPTTFLLYQEGANPRTSTPATQHSDYVRLAFPKSTQEGRGLSPLWVGQEMLLSARGLLRDLGGVVRVPGEWREQRVQAARHLSGLRARETPARTDLCQFRDSKDPDRENPRLADWVEWGIAVKDPKKFRFEVVVELTTGKGDIHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAQ2</accession>
    <name>A0ABR1XAQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674477.1">
        <property type="nucleotide sequence ID" value="XM_066804704.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037764"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="527"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="582" mass="63980" checksum="EF4996B06A25F5CD" modified="2025-10-08" version="1">MHVNVPPSDPNGRSPMDSPAAPFSPYGTPQAKGMGHNYVELGDMKGDGSAGRDREPEETDALPPRPAKSAEESGWWMFEIIACCVSTIALAAILVTLGLMDQRPLHTWPMKITLNSFIAFMSTIAKAALVIPVAEGISQLKWIWFRSKGSLEDIQKFDEASRGSWGSLKLLLYNKQVHLAKLGAFVMIAALCMDPFVQQVVTYPTQMVASPDLNATIPIAREYSNYAPGAMMALRSPTLDMKSAINNGIYNTSPHPSKDFSMKPHCATGNCTWPGTYHSLAICSKCANTTALMEKTNCFQDMCVYKLPNGLSFDSIYRGQLYMNSTSDATAINFNGTQPTITTVSTMRGMHDMSSQDLYGIIANECIFVLLRERVHRRGEERRLQRDAREIPYIGPQSRDDGEHHHHHPPSGNRKTPTNFTMTGIAAGALNYHFWNFWTGNVTGSTGEERGSSDTVRALYDLGDDGRGGGVPKPGGENETMAAVAAAMTKVMRSNLDVDPAKDQEAAAANKVLGVTWYEETYVAVRWPWMILPIGLEVLAFSFLIMTMIQCKRSGVAIWKSSTLPMLQGKVSDLKDSLGTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAZ6</accession>
    <name>A0ABR1XAZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">receptor protein-tyrosine kinase</fullName>
            <ecNumber evidence="2">2.7.10.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_000519</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.1" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674607.1">
        <property type="nucleotide sequence ID" value="XM_066804834.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037894"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044912">
        <property type="entry name" value="Egfr_JX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045319712" description="receptor protein-tyrosine kinase" evidence="11">
        <location>
            <begin position="17"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="195"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="262"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="331"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="371"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="404"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8093834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="442" mass="45923" checksum="8A1E67878D4DAEC6" modified="2025-10-08" version="1">MARLLLYIALGAVVEAIAVERMVAAPTDVSLPSVTFDFAQITAPPSLHELVKRQEAQTVLVGPDNTCGYVSGYLASAYTCNNVQAQCAFLTYSNIGAVACCNSATCGFRLGCVDYAKLATSSCGISCQNDPYTVKCSKSATPYCGTATFFNGIEDYYCMTSRYSTAKQMLTTWIGEDDGRTFSPLVLTVTTSADPSVSHEDGLFGGGDSPTTVTATPSPGGSSTPVGAIVGGVVGGVAILVIVALALFFIIRHNNKKKQRNAAAAANGGYPPQMVQQQPGGPNNGPGGAPPAAGGAMAGHQSVYNPAYDQQQQPPPQQQYPSPTQSPPPQHQQAPPYAYAAPGGDMKPQAYANVMTPPSPTTSPGIEHNNRQSMQPSSPTMTDVSSIHPHHTGGSTMGGAYQYAGNNGSGPNVPTTVHEAGGDAVGNYGPHSNHRGQFHEMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB78</accession>
    <name>A0ABR1XB78_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674674.1">
        <property type="nucleotide sequence ID" value="XM_066804901.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037961"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
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        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="330" mass="36194" checksum="C0B37A18375A3D9C" modified="2025-10-08" version="1">MDFSFQGLVQTHTGQMESAFDKIIKCILHYSRLDVSLVRISNVTEEKGGERFYEGLQIDEYDDVDFFASYSTFHISVDARATNTGPVPASISPMTLDLHNGKGDCFGKIFMPPLNTSMNGARVQVENQLVKITNKPALLEFVGSVMGDTAAVLDLRNGRCDVKALGVGPRSIVYSKMMQMKGMDGPHVTVDQVTSTTKNGGGDVQITLRIANPSPIEISFGTCSFEIQTSGGDDGERKVFAELKGRLDTRKGLFEVKLNGTIDKTVTLEPGKVRLVGKRCVGAGWCDDALKGIDVELHGTLKLLRAIGVETVHAEEILEEKPKGRWFWMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBF1</accession>
    <name>A0ABR1XBF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD/NADP-dependent indole-3-acetaldehyde reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000687</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674775.1">
        <property type="nucleotide sequence ID" value="XM_066805002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038062"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19120">
        <property type="entry name" value="AKR_AKR3C2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044494">
        <property type="entry name" value="AKR3C2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="49"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="321" mass="35388" checksum="6DF0D7B74ADFD1D1" modified="2025-10-08" version="1" fragment="single">ISSFAYSSKMNSMTSAFKPDATGNAPKQMDYMPNLKLNDGNEIPLLGYGLGTARANMDGNSDTDEIVKLTVMAIKNGFYHLDGAEVYGNEEELGAAIKAAGVPREKLYVTTKLNGTKKQDIPTAFATSLRKLGLDYVDLYLVHAPYLAESPAELQEIWRQMEAIKESGKARSIGVSNFLQPDLEAILQTAKIPPAINQIEYHPYLQHGSLLDFHREHHIAVAAYGPLTAVTKAKPGPLDDVYEGLAKKYGVHPADAALRWCIDQGIVAVTTSSSEQRLQSYLNKIPSFKLTPKEVERIAEAGKEKHFRGFWNNKFAADDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBP3</accession>
    <name>A0ABR1XBP3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674888.1">
        <property type="nucleotide sequence ID" value="XM_066805115.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038175"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046694872" evidence="2">
        <location>
            <begin position="25"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="460" mass="51959" checksum="9B6436AD7C55E2CB" modified="2025-10-08" version="1">MKAVRPPNAWRLCLTLLLFPLFSSQEPKANPSACRHSYNWVNWISDGHFDASKDCGDLHFILQAANKKKKKVDFCSAKREHVFGYIRESIDSGIKAGEMPEDCAIEWWWYEGHYPKSPRPFAREQRDRKNKTALSLTQPYHYLIHGPRSQCSRKLREELATIGNPDVAGPGVMASYLVQLLLLAFFSFSTFYRDRIRQRADQSFLFFYGTSMILALSIAIASAVTFAEKRTATGSFRSDLHFPEVYEYRLLTLAPAFALLPVLAAHTLHEARQRGIVFSRRHILLPRALAALVCLLCVVVTWVVWVVGEQGRQSPVQFVFGGGFDIHINDFLYQRAGNYTLAIAILTTILPILGIASMAFSHRLHLSWPALGFRVVCILLALAEVTMLFCIRTMAIKDGKGHTSEIEVGFGQILACFTWFPVLFTLLSGMEFPGVDGATARAPQWIMLHQYNHKLQTNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD07</accession>
    <name>A0ABR1XD07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675353.1">
        <property type="nucleotide sequence ID" value="XM_066805580.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038640"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="29622" checksum="D978931CA8DD7D1A" modified="2025-10-08" version="1">MSEKVEVAPQQPRKRGRPKGWKPGTPYSSHNVGGATPANKPIRKAKSSAAAPGQEPRRRGRPPKPPELTIREWYLRSDPKYLPFGCEWHQENPKGQLTQCPAELQNMDTLRKHVFLIHCNADEPLVCRWGKCGSKLAQTAVGEEATTGKTVHQQPEEFEDEDAFCAHIEKDHLEPYVWHMGDGPQNKGIWTLRQEPKELPRYLFDQDGNQVTPSIKDQQFEDAQGTLERKRRLRAIRRQALENAPDESEFFLQPEDTDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDF0</accession>
    <name>A0ABR1XDF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_001373</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675461.1">
        <property type="nucleotide sequence ID" value="XM_066805688.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038748"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF26">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="23"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="229"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="538"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8094688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="585" mass="63327" checksum="7CBF34E34053FBB6" modified="2025-10-08" version="1">MAVAVPPPRKRARLSGGALIGVITLVDAVSSCWFGYCQGVFAGVLVSEDFQRLFPQTNDAAISGIVTSCFLLGAFFGAIAAFILGDKLGRKRTIALGHSLNLVGAVLQFTSWHLPQLLVGRVVNGVGMGMTSTISPVYLAECARSHLRGRLLVVGASSNVSCFCLANWISYGMYFHDHGAGGAMQWRFPLAFQLVFAAVLALLAWVPESPRWLLLVDRDEEALRVIAQISGGSGGSGGSSSDESSGSDETEEGRNQPQQEDPLVVAEYRSIKTAIRLERESRVPLIDVLCHRDKTQNFRRLLLACGTQFMQQFSGINALDQVRADPCADRIYHSKGFYFPTLLHENVGFDEQMSRLLTAVSGTIYLVAAFCSLFVIDRIGRRKLMLNGAVGMAVCHLIAAICLKVGEDDPSKTKTMGNVTVAMFVLYHVFFSPTWGGVPWVYSAEINSLGWRSRGAAAATGTNWLMAFVVVQFTKAGVDNLRWAFYLIFAAFCICFAPIVFCFYPETSNRTLEDMDQIFIRNPSVLVCGNDEMTQRARPQALVDAETERISSSAAGDDTSGGGGEDSNSGPGPTTVVAVKAGPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDU8</accession>
    <name>A0ABR1XDU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001492</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675580.1">
        <property type="nucleotide sequence ID" value="XM_066805807.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038867"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="149" mass="16495" checksum="AFF4E61D80745555" modified="2025-10-08" version="1">MSIATRTILETLGHDRDSFDPPTGPVYSANDKPAISPSQVPTNRPAHAAAHGAIHGWLNALPSSFVDVPAETDTANQYEYSNQLLALIRHSRKIVPLGNLFTLDSKLQDVPWDNMKMQMLSNLDHLPPLIMALQAISMPLLDTMTFYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE58</accession>
    <name>A0ABR1XE58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675679.1">
        <property type="nucleotide sequence ID" value="XM_066805906.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038966"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="373" mass="39689" checksum="4A819E87D840CDB9" modified="2025-10-08" version="1">MARGTVGFRRADAEALDCERVGMGGVSAPWLGAGNRLKVAPLVWIVDEVRRNEFTEAERRGYGILGGGPSSLPAGSPPMTPSVPEEGRLSCLLGLLGLRASGGGSMVPSAIIATFSWLASMIFDDPLEDVDALCWCRGGSFKSTAMWPSVSGSGSAGPQDPHDTASPEGFRTNGALGGLRFSGEVDTCLDGGSDGGISPPRPRADSWDRSVTGVSLSSRLPSRMSRGLLPLLMVRLWAVRTSTCPDSGRDCGGDDLVPKMEFRTFDQLNGAKPNPAVSPPRGAARQKRYYAATIRMDWLDASFFAPPDAPRWAARLFSLLRRSPDDRPYQGRGQLAYCQVHQVWALLGSEMSPFDVVGGSGDANRSGLVVLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEE8</accession>
    <name>A0ABR1XEE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675767.1">
        <property type="nucleotide sequence ID" value="XM_066805994.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039054"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="109"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="349" mass="38336" checksum="2F10A541F58237C8" modified="2025-10-08" version="1">MLKPAATAAKTPTVPSSSCPSFVHPDYWQLLGSKPPAPPPVVTDLHVLRETTNATTKTVFDAIPLPDGMDITTSTATSADGTEFEITRFAPLSTQDEQTKDPDTPQRAIVFAFGGGLVAGTVPIWRHAIADLAERAGTQVFAPAYRLAPEDPYPAAIDDARRRRARAPEFRVDPARLVTFGVSAGGNLVAAAALRARDEGRLDPPIAAMVLRYPMLDDRTRVEEGDPRLAYLTWRPEANELAWEAYLAKSRFRKGLLTYRVFEADDSIPYTAAPARAQDLRGLPTTFIGVGDLDLFCDESMAFAERLEQQGVRAKAVVYRGVPHGFDMVPSFSSRQELWNDEISFIQQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT50</accession>
    <name>A0ABR1UT50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660707.1">
        <property type="nucleotide sequence ID" value="XM_066818519.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051579"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045634881" evidence="2">
        <location>
            <begin position="21"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="187" mass="19655" checksum="4EC14AF62130D83E" modified="2025-10-08" version="1">MQLATVILGGVAALSHAVIAKPVQNNNNNPIPIPQVSLRDDPSRKTTSANSAQPVQQCERDSLYDLFHEDAHTAKASRYCSKLIQASATTVTATVPFEPTTVYAQTTTVTPATTYVTATDSAQATAIVTSVVYTTVIVPTTAVVATSTVLFTDTDTFTTTAATTFTSVESVITTTTTDATSTDVQTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT62</accession>
    <name>A0ABR1UT62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SPRY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660722.1">
        <property type="nucleotide sequence ID" value="XM_066818534.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051594"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12885">
        <property type="entry name" value="SPRY_RanBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044736">
        <property type="entry name" value="Gid1/RanBPM/SPLA_SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPRY" evidence="2">
        <location>
            <begin position="128"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="255" mass="27966" checksum="8FE07CD44503A104" modified="2025-10-08" version="1">MLIKNQPEAAKADTELQGICAMNGSIRLLEQLYNLGADLYRQDRYGWTPLELAQIENQIEVEFLDLDHPSSTIDVDDISNASSSYRTNYNSNYRNIDNKAQKQYLIVAIGLWARGIIMCPSISWPSAPSARSWAYFGDDGGFFSASETPTATWLRRGPPYGLAGDTVGCGVDFGVGKQRGTATIWFTHNGQRVKQHEFTDVQGRLWPVLGLKHAVKLETRFRGPFLYKGAGAGGTGEEENGKHDGQGLSVGAGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTK7</accession>
    <name>A0ABR1UTK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660849.1">
        <property type="nucleotide sequence ID" value="XM_066818661.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051721"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="667"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="925"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1104"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="935"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="950"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="963"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1080"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1121"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1170" mass="131091" checksum="6A2E49892F27265A" modified="2025-10-08" version="1">MAIRKRNKEEDERERVNLAKTGKPSAENDSGEGGADINDPPKRTGPILELNYAPWHKFRRLSGTEENESYVIDVLEGEPIIDHDVSSSKYAHRIRRLQTPRPSDLGSAVAPGQGPLPERVRIHSNVLRAVLAGMLSTKPSSIGISKSFVVVRPFKSLFHCYDDMKSLITKLEEKLSRKQEPVALTNEAAELEDNTHVEKHEEQATQVEGQSGGDSHPDEQDDYSLYEESSDGDISDGGSSSGSSSDSEDETEKAYDPNDPSKAKRALQHLKTLREFMDSQITAKMEYLQTAECRKVFFADLWYLFRPGQEVIGRDGKQAYRVVHVSSLRHRKAQPWDAWRWYNPQETEKKRKSPFSITCVHIDFDGSSIGPVSKTFDFKQFDGQMEITSLPVYPIRLHPLKKAEVSDKDWSELESLAPEKRYRQHLVNRGARFLTVLGIKPMYYAGPTLGVRDDIESQVVIDFETAFAVEDGKEKQWKPSLEMLLGSPVSEDDEKEDVDPICRGECCRLDAVYDDSYIDDKQRSRYVNSLLPSSRGPSTQPSIAVFPQPLRELVDSESRTGYSISDDELVIMSYRVFGFILRHRQWAELDISYLTELHAHRQPVGVDEPRTKDDTSEGRKFKTAFDNLVLEEEQKPMIQALVAQHFRDKVYKAGQTSQTDIVKGKGKGLILLLHGAPGVGKTSTAEGVAELFNRPLFQITCGDLGTTAREVEKALDINFTLANRWDCILLLDEADVFLAQRNKEDFQRNGLVAVFLRVLEYYAGVLFLTTNRVGDFDEAFTSRIHISLYYPELNCDKTIKVFDINIKMIQERFRDKGRIIVVDNIKTFAAAHYYENRKARWNGRQIRNACRTALALAEFEAQGNSHTAILKPDAVVRLKLSHFETVQKAYLDFAHYMDTIYGSSTDTRAQEGKVRAILELIGENPGNKAKGVSTSKKEEFRNAARARTEPLQQPSTPVTQPVAPQPQPPAAGQPIPQPMYAPGNQQYLNAAALPQGYYQNPMYSQYAQHPMGLPQMQHQFAALPQQMQLIQPPVNPSQPQPQSMMSPNASQVWNSPVATPENNNAQQPRAAPEVHPHTPPSQRQQATNPQQLNVTAAGSPWFGRNIQDMYSAGSPEASGAGYPQQQQQQQQQSGDIGGPPPPGQFSGPSGTVHPTGPHSHQGQWPVSQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTS3</accession>
    <name>A0ABR1UTS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660932.1">
        <property type="nucleotide sequence ID" value="XM_066818744.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051804"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="479"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="582" mass="62832" checksum="291C24D9310C559E" modified="2025-10-08" version="1">MATVTVKEKDGVTPLGSQSSGLGANDLQRLDASLEEFSQQSKKAGKGRKKRPFFMLVAVLLLFLVSGGGVAIAVLSFVKPVEAEGFRLARDLVLVASGMSLLYTIIHVRGGFSNYVNDAPHIPPHFRGEYVHASALIVARLGIPVWIAASVATAILISKSKQPLGISGNQIPYPLLDLIICVVALISFITLAATINKNPTPFALAGISSSWILTYQDNVFVEHDDDEAFVSISRRASMQRAADEKGEKRTTPSIAPSPPPALARPKTTADSSKRTTLTEEALTKATDNGRRVARPNNLDVAKVQAAEEDAKTELMANSPVRPNYYTTMPPVQRNSVPPVPPLPPKVLKAKAKSQKQQQQQQQRHTLAPPSRGGGGWRNDRDDMAHQAGMRPRTRSTYSSSAERTYTMSTYTPSSTMTSHSSAAPMLSTRQLQQQHQQNQQQRPGTSSSHYSTASRSQYGPVQYPIVRASGVPWRPPTRPGSSYQQQQSQGAPQQRTLRHSPSSSLDSNASGSSSRSSSSLGSMTLRTPKPIAGLRTGAQQPRQPAPGGGLPSGPAPPAKSPRRKLQRKTSNFSRPMTANEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTX2</accession>
    <name>A0ABR1UTX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660977.1">
        <property type="nucleotide sequence ID" value="XM_066818789.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051849"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303:SF4">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="6">
        <location>
            <begin position="40"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="414" mass="44350" checksum="A26321B9652C36BC" modified="2025-10-08" version="1">MSNEAIDNVAAEGISYFTPAQVPPSGTGVASKIEGQPLPKLFTPLKLRGVTFPNRVFLSPLCQYSAKNGYANDWHLTHLGGIIQRGPGLAIVEATAVQANGRITPQDVGLWEDGQIEPLKRIVEFAHGQSQKIAIQLAHAGRKATCVAPWLDLNGVATKEVGGWPEDVVAPSAVPWLEGVNPNPRALSVDEIEQFKKDFVAAAKRAVQAGFDVIEIHSAHGYLLHEFLSPVSNKRTDNYGGSFENRTRLLLELTEQVRAAIPEDMPLLVRISASDCSTPTPEASWTVAQSEKLAPLLAARGVDLLDVSSGGAHPKAAAPIKPGPGYQSHFSQAIKKALGDDTRMAVSAVGGINNGPLAEQLLQSGLDVVMAGRWFQKNPGLVYTLADELETEVKMANQIGWGFGGRGKARQKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTZ3</accession>
    <name>A0ABR1UTZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal cellulose binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014264</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase 74 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660766.1">
        <property type="nucleotide sequence ID" value="XM_066818578.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051638"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052025">
        <property type="entry name" value="Xyloglucanase_GH74"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43739:SF2">
        <property type="entry name" value="OLIGOXYLOGLUCAN-REDUCING END-SPECIFIC XYLOGLUCANASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43739">
        <property type="entry name" value="XYLOGLUCANASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045438225" evidence="7">
        <location>
            <begin position="21"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="757" mass="79472" checksum="1A421A861955B443" modified="2025-10-08" version="1">MKNLFASLPALLLLAGGAQAAAEKAAPQQKWESVKLGGGGGFVPGIVFHPKTAGVAYARTDIGGLYRLNPADDSWTAVTDAIADNSGWHNWGVDALAVDPTDDEKVFAAFGLYTNDWDPTNGQIGRSADRGETWEFADLPFKVGGNMPGRGMGERLAVDPANPKILYFGARSGNGLWKSTDGGATFAKVDSFKAVGTYAPVPGDTTGLNSDIQGLTFVTFDTTSAKAEGGATSRIFVGTADNKTASLYVTEDAGATWAAIKDQPKKFFPHKGKLSAAEKALYISYADGSGPYDGTDGAVYRYDIEKGAFTDITPSIGEKIAFGFGGLALDAQKPGTVVVSSLNSWWPDQHIFRSTDSGKTWSRLWEWANYPEMNLRYKQNVDKAPWIGPGFLDNDTKHLGWMIECLEIDPHDSDHWLYGTGLTLYGGHDLTKWDADSWDEKLTISALADGIEETSVQDVASIPGGTELLAATGDVSGFTFKSAETLGEAPKKNWYDPHWTTNAGVDFAGAAGKNVVRIGNSAGTKQLALSSDGGDTWAEHPGADTKAAAGVVAMSADGETIVWSASPGGVLRSQGGKEAFKAVSSLPEGAVVASDKQNATVFYGASGGNFYVSTDAGLTFKVAAGELKGAKNIVDVAAHPVKAGDVWVSTDAGVFHSTNYGATFAATSTALKNTQQVALGVGNVKDSWNVYAFGEGRGGRATTWVDIQGDKQGFGTISSGKLAGSGNVAGLVYVGTNGRGVFRATVSLGVRSRVRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUC9</accession>
    <name>A0ABR1UUC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CIA30 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CIA30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661101.1">
        <property type="nucleotide sequence ID" value="XM_066818913.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051973"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194:SF19">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30" evidence="2">
        <location>
            <begin position="18"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="190" mass="20380" checksum="48F92E11D6010C10" modified="2025-10-08" version="1">MALQQLPLLGGTLPWNASLWEAVDDSVRGGNSSSHLSIAATKNEATFSGYLDDITLGGAGFASQQTVGSLDWNLTGYDGLLVSIALSDGKLYTLNLKDVLPASDRESSLLYETNFTVPAGSDLASAQEVFLPWVNFTATYRGRAQPDAKPLNTSSIKTISFMMRSYFGKQEGAFSLTIKSISAFCKSCLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUV5</accession>
    <name>A0ABR1UUV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661307.1">
        <property type="nucleotide sequence ID" value="XM_066819119.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052179"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="349" mass="38875" checksum="B5FC2E6F58709780" modified="2025-10-08" version="1">MDADQELKRRRERGRQAQAAFRKRQAKAAQSVQEENKSLREAIESIIHAANRSDRPGLLQVIREAAAAAGIEAKHLEASTSTSDDITLSADAREVGFPSNGCTTDTNITAIGSTLVNAQPSKSRAASPVTWSTTNRPPVTIGNFWFDPLRSTNITTTHQDVVPYVGQGRYTLGGLLFWGVLDHVTNACTHRHHPRSCEELKSLVRRTTAHSKSLSRVRPEFINSLAAKARQQYLQNGYVDDRYAPATEWSSLAAMRSMVDEDYASKGRDTSAWLLPKDVEGRVRRGLGREMFDRLEQAARAPESSQAHRALKETIHKMVDAFMCFGNGPSWQDSFVDTVFTEWALLKPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUY5</accession>
    <name>A0ABR1UUY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661337.1">
        <property type="nucleotide sequence ID" value="XM_066819149.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052209"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21625" checksum="61AD0A649B3A0FCF" modified="2025-10-08" version="1">MLTALRADLRKRILAIASTGFVFIILAIVTGCDAFSGEDYGPASFFACIGQLIWTTFVLGYLYPGVINDCTRYWYSVVAGSVSLLADTIVFMIVSFRVWSTVPFVFFLSFWISFAAEHYIGIISRPVEWYVNRTVPIQRQGAPAGGQAQPDGANPEVVPITEVMWEGRDEQEYELPPEYDHECDSRPETPQCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVS8</accession>
    <name>A0ABR1UVS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660749.1">
        <property type="nucleotide sequence ID" value="XM_066818561.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051621"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="471" mass="52539" checksum="CA692A50ECFFBAC9" modified="2025-10-08" version="1">MSRVHARDDDSDSETEPHRARDPRHGHGHAGPHPARWARRRFVYPLPAQRPREQTAAPPYSTAFPWNDHAAASQFCCSPDPNFLTLLLAKSLHRNLKNGEWQQGLRQSWAGEVKTELIRMAREASDYATQRCIISGSCGRPLGFTTARPIACSATCQEEFDKWPLSVRLSPLLRDPSVLDLLLSCLSSQLTALIAEPLLNPDKMPTPSLGCQDHVQLLLVLDTFPSMKPGITLKDIVDSGERGSERNDVLSWLCSKFQGMIVSAPASDQVMFRMPEGSQDLKRKGDAYFNPKIYLLLNTNAQRQKLLEEQLAREGQKGGGSAAFHGTPAQNALSILCNGLKQNVHADGDVWYSSDPFYSTYYMWRCLPRKGHQLLYRSWGNSNFKNQQLLFGLEAAGPTGLESKAAESCPQERLMVRHLFVIPAEMAESCREVQGGDGAWAKNTIRPKMEETFARIHDGSVVRDVQLEATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVX5</accession>
    <name>A0ABR1UVX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661685.1">
        <property type="nucleotide sequence ID" value="XM_066819497.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052557"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8063086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="166" mass="18798" checksum="BFFF438D4F1A6DC9" modified="2025-10-08" version="1">MPRASRRWVQRSRPPTDRLGSSSRSDQKTPSAHKMCHGHPHYHTCHHTSVKWLYCPEAMFDLETGYETPCSNPIYSTPQLASGECPLQNCLFKQLKGDRWTCCRCGHNANKEGWCVGKINHPFGSWTPRGLEPQNWQTCGHGYCGKCSRDCETHICSRTGMIMTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UX27</accession>
    <name>A0ABR1UX27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660988.1">
        <property type="nucleotide sequence ID" value="XM_066818800.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051860"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="3"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="339" mass="38642" checksum="0A431A64E62F138E" modified="2025-10-08" version="1">MTFAKFPELPTELQLYVWQCALLAESQDRLVLVHRTNHIIPQSHLCSPYLSTSRLSRIEALRFYTVPLKVGVLPLVPPMVRERVRQYSVSQDVLGHRPRGSGRHYLHSLCRAQRRGTVYLNPTHDTFIIGLCFIMHFAAAFSSGAMLGERYPEFVAVGTNRNRPLGRLFAGALPLAACREVRNLVLAQRGIRNRKDRGLIAAVPSSRPGEPVLTLVRSIYLRPRAEVTWKRSFFSGCTDFRHLWVQVPREERCYGRVFGKDAEYKLSGPEACAWALFQDLQEHGGSRHRLDIRTWPVKERNGLQHVSDPEDVVNGGPFTVMYVMMAKFQGPYAMWINNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V203</accession>
    <name>A0ABR1V203_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661985.1">
        <property type="nucleotide sequence ID" value="XM_066816293.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049353"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="120" mass="14019" checksum="9BAE9B9328071418" modified="2025-10-08" version="1">MDHFTIFQVIGTAVSLTDVVIKSITKLKSIRTRYLLDRLASRNSQERNQYPRYQQLGLQIGNSLDNFSLLILALQQQLDRFEGVSPARMGAKKKLKFMWSEKDMSKFSILLDRQLNRQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2L7</accession>
    <name>A0ABR1V2L7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CS-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012177</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662183.1">
        <property type="nucleotide sequence ID" value="XM_066816491.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049551"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF3">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="20"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="179" mass="19914" checksum="3C85C7036AD0BA2C" modified="2025-10-08" version="1">MADKDPQADAAAIAKEQEEQDALPYKWTQTIAELDVVISGIPGNYKGRDIVVDIKKNKLVAGVKGQTPSSITSESTWTLSSNADGTKSVEIHLDKQNKMEWWAHVVTSAPKIDVSRIQPENSKLSDLDGATRGMVEKMMFDQRQKEQGLPTSDEQKKADILKKFQDQHPEMDFSNAKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V383</accession>
    <name>A0ABR1V383_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Peptide hydrolase</fullName>
            <ecNumber evidence="15">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">PG997_012154</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in vacuolar sorting and osmoregulation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="15"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662160.1">
        <property type="nucleotide sequence ID" value="XM_066816468.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049528"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03875">
        <property type="entry name" value="M28_Fxna_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048024">
        <property type="entry name" value="Fxna-like_M28_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053975">
        <property type="entry name" value="PFF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053976">
        <property type="entry name" value="PFF1_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF58">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22250">
        <property type="entry name" value="PFF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22251">
        <property type="entry name" value="PFF1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <keyword evidence="10 15" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="464"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="528"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="656"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="695"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="725"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="18">
        <location>
            <begin position="171"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease transmembrane" evidence="20">
        <location>
            <begin position="431"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease C-terminal" evidence="19">
        <location>
            <begin position="750"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="560"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="564"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="578"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF22250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF22251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK8065407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="969" mass="107072" checksum="CA8F310006EE2667" modified="2025-10-08" version="1">MVANPLAFRPSQVTVITTVVYIAVIVALLFVQHTVPAPPSETPYAGVNITEAWLDLKELSNGYHPYNSRKNDKVRDWLLTRIHELLKANGVSYGVESAAMRVSTADNNAPVVVFNDMTSNLTFSAASGVASTAPSVSTYFEGTNIIVYVRGSQDDEGDWWRRRGQPSSGGSMVNAHYDSVSTGHGATDDGVGVITLLQLIKHFTTEGNQPTKGFVALFNNGEEDYLNGARVFGRHPVSAFPRVFLNLEGAGAGGRATLFRATDLQAAAAYKKSPHPFGTIVSGDAFKSGFIRSQTDYVVFNGNMGMRGLDVAFMEPRARYHTEDDDARHTSPNSIWHMLSAAVTTMQALTSDTGETFEGDAAGKHKVPSGQASFPLRRLGVTPGCRPLALLLIGAILSHFDKFYLFSHCLPPHPESDHDQSISLHSLRGILRFPTIFIASTAILVGLAFMLNKLNPFIVYSSPYAVWAMMASAWIYCMWFLARATNFIRPTALNRHYALLWLFVVGWVLLVVETVYEERYQLALGYPVVWYFLAVSAATLLGFLELFSLPTKFQYAEDQSFEADAQRPRTVDSDPQDRPQSSGTQPNAVTNGENQDDTEEATESTSLLRGSKTTFARYNRSDHLSTGSNVGLQERSIGSQSVFGDEQIWSQYLSDWVWVFQFLILAPITTIILGQIGLLLMTATNQTLVDGSSALLVYILVGLMSVLVFTPLSPFVHRHTYHMPTVLLFVFIGTLIYNLTAFPFSPTSRMKFFFVQRLNLDTGINQVCLAGVESSFMDDIVGSLPSTAGKEIVKQTSSARSGLTEYSWKGIAPRVVPTNGTLPPEKTYSQWLSLNVTRAKGLNSASIRVSGRNTRSCRIFFDRPVDDIVVKGSDQDPRFPRIGEAGSKELRLWSREWARPWDVTFSWKSSKGKNVGEEGMDGRVVCLWNDQDERTAIPALKEVRRFAPDWSTVTKMGDGLVEGSKSFMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4U2</accession>
    <name>A0ABR1V4U2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012967</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662973.1">
        <property type="nucleotide sequence ID" value="XM_066817281.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050341"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="518" mass="59154" checksum="65B7B4C1C6200F5A" modified="2025-10-08" version="1">MELAPDLREYVRALSLQQWILTGILLIALDLVCIAVYRLCLSPLARFPGPKLAALTYWVETYYELFVGEGGQFPFEYQKWHKKYGPIIRINPTEIHIEDSYYYETFYAANKPVRKVEALSRRFGNPTAIFNTSPHDLHRKRRAPLAPLFSKRKISSRCHLIQRKVDEVCEIIKSEYKGAGKVLNCKNMFACLACDVMVDYCFGSKGDCIYHPDFAAPLIVATSSLVEPIHWFTQFPVLQTMASVLPDWLTDKLDPNIKHIRKLNSEVMEQCTKTIKAVDAGMTKDESDTIVVSLLRADLPKEEKTLLRLFDETVSLVGAGLEAPARGMNVALFHILNNPPALRTLQKELQEAIPDPDIMPPWEELQQLPWLNCCIEESLRLTYGTSQRMPRILDKEPTIYKEWVIPAGTIVSMDNWPVSHDETIFPDSFSFKPERWLGSPKAPDGKSLQRYQVAFARGTRGCLGTQLGYAELFITIATLFRRFDFAPHEFDIKDVEFHRDRLAVRPPLSSKGVRVLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V521</accession>
    <name>A0ABR1V521_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component Sec8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013045</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663051.1">
        <property type="nucleotide sequence ID" value="XM_066817359.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050419"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039682">
        <property type="entry name" value="Sec8/EXOC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007191">
        <property type="entry name" value="Sec8_exocyst_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048630">
        <property type="entry name" value="Sec8_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20652">
        <property type="entry name" value="Sec8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04048">
        <property type="entry name" value="Sec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec8 N-terminal" evidence="6">
        <location>
            <begin position="82"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec8 middle helical bundle" evidence="7">
        <location>
            <begin position="333"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1072" mass="120307" checksum="1E8B6EC523B5937F" modified="2025-10-08" version="1">MANRYGGGASYRNGGANGYGSYGRKDLPQNGGGGDDYDQFGEGYGSERYATPPQQMNPRRPPPSTRLGMALLATQSSAERQISQVLEQVKAEWPALCEANCIPASLALQLLDTSSVGRAHEYRNFQQTHQYLQDSLKGIVHEHHQGFNSSIGTFHKIQGSIQSSQKRVRTLKESLNTSRANLCSTDPELKKMYKASHMYDEVLQTLNELEDLRTVPDQLEARISEKRFLTAVEVLHNALRKLRKPELDDIGALSDLRSYLANQETALMDILVEELHEHLYLKSPYCQERWQNLAKKQDGYNESYGDQSNITPFHVVLDNLDLRHAVVEDPAKNPEADTFWYVSLLVEALNKLGRLEGAVDNLKQRLPVELFSIVNETINEVDQRHPSSLRGGSLSQEGLHMYGSRETQMRADVIYDLLWTLYGKFEAIAEGHRVFHESIKALIRREGSGNNNALLGSFKELWNLYQNEIRSLLHNYVTTDADVYQYNNSPNLGGSLNGNKDAGRDHLFKFSEADSKSVEMTTEYEALDSIIRAAVPGLTSGERKNKEDKKGGKELQRNAMLGAYENRQAPGSYKSLVEPSVFNMSLLLPPTLVFLQRLKVIVPPGSDLAASTLTSFLDNFLVNVFQPQLDETLAKLSDNVFAEIDSFQQDADWSLVARRPVFKGTTSFFTIVTAFCRMLGTIPHDQALSSLLISQMMRYQERCQAWFRSLVSKAQEPATSSVALRYSAELATTTGDLQETIKKLWTSENLDLELLEKEVNLLILQTNERKLEPNDVIQDRDVISSLCLLYTSMKWLAVKAVALRHITSHETDSSRPTMPKTQNRRWTLLNDPNKATSDQSGPVYLPMTQDTVQSFDRLVASYEELAGSVLLTLHTEIRARIIHSLSISVSPTTAPYVLPPDQEIKEPDQEIITLNSELVAYDETIVRFLRDTEIDFVRTGLGRLVNAYLVSNALVAQPMNTRGCERIQLNILVLQQNLKNIEAGVDLARAANYFSLFTAGPDGVVEKAKKDAQAGAHGGVPEREKFSYDELKAMLELCYSEQLSHAERGIAAAAKRQMGEKVLALSEYMWQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V750</accession>
    <name>A0ABR1V750_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012827</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662833.1">
        <property type="nucleotide sequence ID" value="XM_066817141.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050201"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046707">
        <property type="entry name" value="DUF6780"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20571">
        <property type="entry name" value="DUF6780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="639"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="Septin-type G" evidence="4">
        <location>
            <begin position="201"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="682" mass="74324" checksum="4F0965C0AF157324" modified="2025-10-08" version="1">MRPLPGDDAFGRHRATDYPPRAITTASNQMSFFLADEATLDACLERPTIPRPRDARKAHDSAATAGRKDDREPDISRHQDIARQSAARDAGLALAPSPVPRASVATHSPASIRSHDFQSLSRPMTPMTLGTSCGGSIISTPSSRRNSLSGSISEIAVSSDEDDEPLRREISSIMDSGSAPQLVMPSIQMPSRRPFTDVGKSIGRLKVLVAGDSGVGKTSLIKAIVQTCEHIVHVDPIVSPANSRRSSRINDKTTGPRRKPSDSTTQITEIFASTKPYPEWWAELEGSRFDSRRKSLGDNVLDRNICFVDTPGYGRGSSAMEGIVPCVDYVESHLTRASSDSLNDQEMLHLFGGGGGFQVDAVLYMIDGGLKPADVEYIRRLAALTNVIPLLARADSHSTDDVKSLKQKISRQLDESGIQPFSFSSINIDTISSGALSGLYAVSSATGSDHDVMDASLLMSSEYVQPLVPTELGALVEQLLSPNGSSWLRHSAVKKYLRWREVANPSRPKSLYQPLSLPPTQAASPMAPTSLALARINSPTRNSDPPQLRLVDWAAELQRSMVNERVQYEALAKGERAMWLTERLDECVKEGTLVPVNVPKAGRTGKKRSMNRKSSRCTLRHQDPLGLLQVVADMKAKGWVALEFLGGLGIIGGLAYLLARQRWQSEPALLADEWARLWGMDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7B0</accession>
    <name>A0ABR1V7B0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013828</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663834.1">
        <property type="nucleotide sequence ID" value="XM_066818142.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051202"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="260" mass="28986" checksum="ADBF52FE872F217D" modified="2025-10-08" version="1">MVPPREEPPVAQHLTFVRPPSATSSYSHLSGQPLGDDPSIAIGSPLPTSGGSPRTRSGNGLLHAQIRSLQRQLQSKNEEVLQLRRQLETRENVDVGTLSEKLREAKRDCAMWRDRAEAAEKRIAVFEKFAAKARALRGGTSPGTKEKREAMTQEESGTGSMKLTRQSTPLATLRGESDETAHTEDQETFNDRLRRSMRRTTRPAGDGAMSSPSGDESIMDLSLENMLNGTDYMPLTWRGRALWMAVEELLNMQDEMEHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7W6</accession>
    <name>A0ABR1V7W6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664039.1">
        <property type="nucleotide sequence ID" value="XM_066818347.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051407"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37048">
        <property type="entry name" value="QUESTIONABLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37048:SF2">
        <property type="entry name" value="QUESTIONABLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="259" mass="28698" checksum="C24F943923A4D607" modified="2025-10-08" version="1">MTSAHLPGLILWLPKQDPSQETIPGMDEGAYNHPVVVLSAFARDGKVIMLPLTSFDETDLLERHRKSPHKRKSYLPIDPANAHPDNGISKHEISLDILRPYQRNAEFVLSKASYQDLIEYCGFQQPLPSPAPECVPGTFERIPTPYTPAHPPSGARFQVTRSPILDTGLRRWTDTNPTFLNQGRSHYTTHYGTVSANHHPGHSLAITPRSAQTYSVPDYHASRVGRSSWQSDAHARSNIPFQGDPDTNDPGCPVNIGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V818</accession>
    <name>A0ABR1V818_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014083</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664089.1">
        <property type="nucleotide sequence ID" value="XM_066818397.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051457"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF30">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04702)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="435"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8067336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="551" mass="61463" checksum="07CB347D04D8DFE7" modified="2025-10-08" version="1">MASNAASMPPVEVDVSSIPGTVHLVDLEHILATRHAADQKDIILVPTPSLDYDDPLELVQAAQAPGPGMRPIVSPSREPPIYRDHLRLIVFTWFNGMALSVVYSVLVPLSKALDVTENDLNAGTGYMFLLLGWSLLFWQPFALQYGKRLTYLLSLAGLIGVTVWSPFAHGNGQWIAKSILTGFFGSPIEALPETTIADLFFAHDRATYMGWYAFMLAGSNYFAPLICGFINDGMGYKWVFYFPAIFCGVAWVFMFFFMEETNYDRRSIGVLANPPVEPKSRISTPMVAARIGEYPKKGYVDKLSLIDKPRPFMMHYRAWQSIKLLSWPVVFYSGFSYGTYVVYFNILNATTSIILGGPPYSFSPSMVGLSYVSPIIGTIVASVFTGLVSDRFIIRLARKNNGISEPEHRLWLFTISAIVVPFSFILWGVGAAHNVHWFGLVFAMGTLAYASTTGVTLSVSYLIDTYRDISGDALTTCILIRNTMSFAIGYGITPWLKNLGLQNCFISISFIGLAICCAFLVMINWGMKFREKKRVQYWNEVKSRVNMGLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGS0</accession>
    <name>A0ABR1VGS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664246.1">
        <property type="nucleotide sequence ID" value="XM_066814956.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048016"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="254" mass="27832" checksum="FF903450297CAF7C" modified="2025-10-08" version="1">MFISSNNMIMMPWFILQQYYYPAPEYTTDSVSGPGPLRLGHIIPKWNLLENVINADGPQDLPPETPIHASTVCGSVSKMDGEAKQEQTADGRIHVRAAAAAAMNVDPRKIRLPSNSLSMRVKALETQVIQPNLAYVKKSVAAKEIASFLPRTSTFLSPPQTVYMITGLMIARGATNPIPSCLLNHFGRPAEANRNGIIVYATDSVWAIRLATISRGGLGVGRKRNIPRRPTSGAKTWGFAEMSYMITGTAVWFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH80</accession>
    <name>A0ABR1VH80_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010804</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664409.1">
        <property type="nucleotide sequence ID" value="XM_066815119.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048179"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF116">
        <property type="entry name" value="TYROSINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046270625" description="Tyrosinase copper-binding domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="3">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8070601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="394" mass="42974" checksum="8BA56427464C6052" modified="2025-10-08" version="1">MHLLRLALSATTLLSLAAGKHCYVPEPTDGTDLLAEQSLSKLRESVADEHDVAQACTLENAAVRREYSTLTSNEKLAYTAAIKCLMAKPPRTPPDLAPGVRSRYDDFVATHINATNTIHFTGNFLSWHRYYIWAFEAALRDECGYADYLPYWNWGKSAQDPERSPYMDGSATSQGGNGAYAPHACTPALISGQGCVPAGNGGGCVETGPYAGMVANLSATGPTFPGIRTGLPPLGYQPRCVRRDISAWVSRQWSTDAQSVDLLTNPAYQTDIRAFQDRLQGGNVSDIFTSTFFGVHSAGHFTWGGDPGGDVAGSPMDPMFWLHHSQIDRTWWIWQNQKPLERIFQIAGTRTILNSPASSEASIEDLLDLHYTAPASAVKNHLSSMGGPYCYIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHA3</accession>
    <name>A0ABR1VHA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664423.1">
        <property type="nucleotide sequence ID" value="XM_066815133.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048193"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="376" mass="42368" checksum="2C21CF8A9D4276BA" modified="2025-10-08" version="1">METREERLATWAVPLVGHHHYLRFLEGSLNSDPNNTNDVSKVSEAKLQFDEVGDHLLQKTAAVEDAETPKQWHFKVLSLPRIRPGGLVLSVPRGIFQLIQGYWYLLPRTVDVFLSNNAIFTSADCPASGRRSAVWKVANSRSTGFDCVSMSSDRADRTTYILYHHLADEDAVFGALLATSERCVDHYFFVSVLYWSPHQQIEAHRNFIDDAVLGIERRTRFGHPGRLMDGLGGRPDLDDHYSTTMEDPKTTIRQLGYCQTDLAVIGHVPRACLDAGEQLVRAIEEDQRNLALLTDDDDDDDPLELNARPGYHRLGAALTMTRGDVEYARRRTAMLLSQVQQMKDRSQNQTSFVSIYLIPRGAILDSVLLQLGAPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI18</accession>
    <name>A0ABR1VI18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycoside hydrolase family 43 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664638.1">
        <property type="nucleotide sequence ID" value="XM_066815348.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048408"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043750">
        <property type="entry name" value="DUF5695"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18951">
        <property type="entry name" value="DUF5695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047521892" description="Glycoside hydrolase family 43 protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="907" mass="98563" checksum="E43BDC6AB68A0415" modified="2025-10-08" version="1">MFGFVIILLSLCASLAVAQSDDNLGLRNGYLSLTTKNFELKLVKDAGVLVSLKPAGDSFDFLPFDYLRYRARNGQYHWGDITYRYREASTGGNGGGGRWIDGDSAAARKPVQGKTNEPGDLASSVLTPTLPGGSPINVTRRWTEVSGGDLGLRFTVRNHGRVAIELGSLGFPTEFNSIFTGRPAAEMARVCSLSDPYIGMHAGHIRVAPTKGNGPALVVTPLMLSGENSSSYTGTPMEAYRNLREDHYDEQTAYGSQTFEGLYEWQVLTKAWAENEWSGVEPWNKPSSRVLQPGDSLEFGLRFSVAKGACESSTLLFVGIPGYIVSQGSTAMLYLQSTSGVESVTVNPSGALIATRQSEGKYSVTPGGSAWGRARLGIQYGDGKLQTVHYFITKPGASAVSDLGCFSTTEQWFNDTTDPFGRAPSVMTYDYEAKAIVTQDPRAWVAGLSDEGGAGSFLAAAMKQAVQPSTEEVAKLESFVDGVLWKTIQTADFSVRKSIFYYEPSKIPGYQYNPSFDWSVWWSWNKQASYAIDRAYDYVHVAATYWALYRVARAYSALTRSHTWDFYLNQAYQTIVRSMKSDVGYNRVGLMGETVFGEILADLKREGQASKVSSLEQSMRTRATQWDSKEVPFGSEMAWDSTGQEGVYYWTSYFGFKNTALKTVNSVLGFMPAVPHWGWNGNARRYWDNIYGGKLQRIERQIHHYGSGLNSLVLLSAFRRDPSDAYLLRVGYGGVSGPLSSINADGFAAASFHSWPDTLKWDGYSGDYGPNFVGLALGSGTYVADMGDGGDGLGLVAFGGSLKVESGGRVTVITGDPVRKRVFIGPLGVLLNVDAGIISEFSYDAGGSISVTLSQLNGVPNADAAVLWVETPSSSVNYTVTTSGLQKTRGGWKVPLSTDAIVELSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIX6</accession>
    <name>A0ABR1VIX6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PLC-like phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664968.1">
        <property type="nucleotide sequence ID" value="XM_066815678.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048738"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF146">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045554002" evidence="1">
        <location>
            <begin position="18"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="31749" checksum="89DC18D2B56C9EFE" modified="2025-10-08" version="1">MRAFAALALAFAPVALALDCNGHTELCDRKYSNVTFMGAHDSSFVGILPSDNQLESVTKQLSGGIRYLTAQTHPKDDAIELCHTSCILLDAGPLQDYLGDIKAWMDGNPNEVVTLLLTNGDAIDINKFGDAFKAVGLDTYAYTPGAELTMDDWPTLGTMVSNKQRLVVFMDYHADTSKVPWILDEFKYYFETPFDTTDKNFAQCTLDRPQGATADGRMYIVNHFLDIEIFPGVLIPNLADAGTTNSMTSILAQTDLCYGQYKRTPNVVLLDFVSIGDAMKAQNDLNNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTA5</accession>
    <name>A0ABR1VTA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665429.1">
        <property type="nucleotide sequence ID" value="XM_066813467.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046527"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF92">
        <property type="entry name" value="OXYSTEROL BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="416"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="475" mass="51272" checksum="4B6F04E15827E71E" modified="2025-10-08" version="1">MTKPQSNFAQLRDFLSYLATVKGDLSNITAPPFVLSPRSVTEIPAAWAEHQPLFLAPATEPDPARRALLVLENFLCSLKGQVYTASASADSGSNSGSDGGVKKPLNAFLGNCFWGPTQLISEQVSHHPPVTACCLYNKAHGISSSGYVAQQTTFSVSRGVVVRQVGHAIIRDEGHGESHLMTLPTMVVKNLMLGCPYPELTGTCYLVSSSGYLSTVVFEGRRTSLYGMGKSNRARNSVRATLVNLREENRPLFEVAGQWNGVLQVKDLRQEGSSPVIDEFHVDHVARSKLQTKPLSEQSPWESRRAWAGVHAGIRAGDLPKVSAAKTDIEEGQRAIRRAEREAGGGLEWPRLFFRRAEGDQEFAVLARAIPDPEARGLQMERTGGVWRFVGVRAAERLLEAGGGIGGFHRGLAPTGQLVEDCDGDSKRSSSSSSSSLEEVATPSPTSSFEDPIEKQSSPATVSIYSSSSGDDRSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTG9</accession>
    <name>A0ABR1VTG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665506.1">
        <property type="nucleotide sequence ID" value="XM_066813544.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046604"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="223" mass="24359" checksum="FEC696F4A1681C9C" modified="2025-10-08" version="1">MDVATADGHPSRVQEGDTRFLFTTALYTCVGIAVSGTYPPPADGQTPTTSATNERYDRFMIHTSEFNMKNTCPVLRKEVEAAKAQGLQDLQVHVTTTDPASMVGKEEPLYIVHRHTNAARLMRFLRQLVGSNVNSDDQPRIHWYPYPHCQNLDCASMAMFSDGSVVVEHQNQARFSEPITRWRLQEKPWVSTAPAVATGSGGSSSNPPPATGTGPSGGNNNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUV0</accession>
    <name>A0ABR1VUV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ATP-dependent helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_009615</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665892.1">
        <property type="nucleotide sequence ID" value="XM_066813930.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046990"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF16">
        <property type="entry name" value="ATP-DEPENDENT HELICASE ULS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="395"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="749"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="947"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="68"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="224"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="291"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="823"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="835"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="880"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8074952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1118" mass="126030" checksum="2197BF62165919B8" modified="2025-10-08" version="1">MAQPGRPPVPIWDEAEPAAPSEEDLRDELQLQEILLESLAGTPEDTPQRRAEIQAEIVRIETQLKRLQVARPGSVQPSHRTSTNNTAMAGSSGDEPGARRTFPVPLPNAQSISGLSFECENLWDDASNTEYARKRTYSNHLDNGLPSMPESKSQRVGDEGNTWDDELFGDFGDDHGVARRSEYEQREIAFRQKQIQEEQDEALARMIAAEDGAEAQEYFAHQPEPIDSSSSLPQTTPNDFSPQANRMPGSWETNDSNFVDLTDDQPRHASSAANNSGDLAHHAAIQRQRLESNSPFPSSQSQRRPGYIANGTASPLASRTNNSVYRPSLAEIVQRTNNYDYASGTNERGDPLDDRIVIPPGYAAEMESESDQHTPALKEPLYKHQQIALKWMKGMEADEYKRGGILADDMGLGKTISTLALLVDGRVPASQTSPGRLGTSVVVAPVSLLRQWETEIKDKVKHTHLLKVHDYHKKKLSYDELRKFDVVLTSYGKLGTELKAMDAFTKDKISRGESVDKNILAEKFPFICAKESFLRLIVDESQMIKNKSTQMHQAVCRVPAKYRWCLSGTPMMNNVDEMGSLIHFLQIKPYNDPQEFKRKFAALYPKGRSFEDPQKVMKSLQVLLRAIMLRRTKTSTIDGAPIITLPSKTEMTDYVVFTEDEQQYYNDLLHQSRVEFSKFLRAGTVGKHYQAMLVKLLRLRQACCHPYLHITDLEFTNIEMSEQEMATLAKEIHSARVDALKEEETPLECPICMEISWNPSILVPCGHYACHECLQLHTNSSEQQRNELENGKAKPRCVICRAEFDMKGTVTYEAFKSVFMPETRGDSQAQSADGDVADVESDSDSDSDSDSTDSAEDGDDIDDRGNLKDFIVDDDDDEEYQPKSKSKDKGKGKVKSEKKRGKKKKEADIQPHMLGKLRKEATRNAHAHKKYLKYLGNIWLPSAKITKCIEVIRGIQESGEKTIVFSQWTLLLDLLEVPLKQDLGLRFRRYDGGMSAKQRDEAVQQFREDPNVKVLVTSLKAGNAGLNLVCASRVIILDPFWNPFIEKQAVDRTYRIGQRKPVEVHRILIKDTVEDRIMVLQEEKRDIVEGAMDEKAARDLGRLSNSDLAYIFGMGGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWH3</accession>
    <name>A0ABR1VWH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666541.1">
        <property type="nucleotide sequence ID" value="XM_066814579.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047639"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="487" mass="53317" checksum="E427BCDDBD48F611" modified="2025-10-08" version="1">MTVTHRFQDCVSFEPSQTVNMAWLLEDEAYLHSVLLVASAMWEEGPTKSKRGCHQSTRTGHYMNKTLASLREGLSPTSTDPTNGHPGVSSPTADVINDDQEATSTSSSLRDSRISVVATLVILSTLAGDTRALQAHVAGLTQMVRLRGGMKRIRQNPALYAKLRRVDVLWSLYCGEQPLFLPSYHDIASYEPYDDSCLGQQQSVDYRFGYPLVSPPLITKPISRLPLQPCKTLQTLIGADEGRLLAIFRAQQKISRRLNAALATGQPLAEAEFRDLVSESQCGLVALRGRCATIPAECLRLALLVILTTTMNLPSPAAQGSSPLTTGDEAAAAAKEDGARKFEACVRSLEIPSPSPSPSSAASSEDESDDDDLEPDFLLWLLLVGAVSLYGVDRAWLRELWRYHVVPRNLTCWDEVAARLRRRWVWVDAVHDGLGRHAFEVLTFGRRQTTAAAQEEGKDGDGGMGTVDGPRGCCGRVGGRYVLFGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXA3</accession>
    <name>A0ABR1VXA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665403.1">
        <property type="nucleotide sequence ID" value="XM_066813441.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046501"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="41685" checksum="919BBC053B9ADB05" modified="2025-10-08" version="1">MARLDDLPNELYLEILQQCHPRDMLALIRASPPIFRVFHWYRPNIINPLIRRLFVVPRPSLILTVARLRLLGSRYKSTEDYEQRVRSDFDRFMPEEYEHGLAKEWPSDLPTLAVLADVCFELDFLTETIRKEHWDGMLYRANAAQRDSGSEAVPIPTQLGAEETWLVQSGLLFYELYCRLFHHGAHTLHFDTPRFRERVCGQTNNFLPAIEFVHHEHWKIFLGVLNDGNARRICSSSSEPTQQPPLRHTWHQVTKRAKFVRYLCSFGTQLITKVSQCPPLEREALILSKLSDFETLGTTHPRYYFPSLMIYQRRSVTVLRSGPNSSRYTETMAGAINGTWDLGSSIGAKNINHKRSGGIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXS1</accession>
    <name>A0ABR1VXS1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Purine nucleoside permease-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666577.1">
        <property type="nucleotide sequence ID" value="XM_066814615.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047675"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009486">
        <property type="entry name" value="Pur_nuclsid_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38643">
        <property type="entry name" value="PURINE NUCLEOSIDE PERMEASE C285.05-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38643:SF1">
        <property type="entry name" value="PURINE NUCLEOSIDE PERMEASE C285.05-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06516">
        <property type="entry name" value="NUP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF013171">
        <property type="entry name" value="Pur_nuclsid_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="417" mass="42930" checksum="B45923ACDA809452" modified="2025-10-08" version="1">MSRSLLDTNFTIDGLSPLNPQVHCTNSGEVCQATLGESEINAAASMSALVLGADAANLFDFGRTYFLISGIAGVNPKLGTLGSVALAKFAVQAALQYELDARDMPTNWTTGYLAYGTDAPGRLPTIFYGTEVMELNEALRDAAFALARDTHGDGGNDDDDDNSTPVLDDDAAAAAYRSKYRVNDLTTTTTTGDTTTDDGGGTHHPAANNIYAAATGPPSVLRCDTVTSDVYYSGALLSEAFENTTRAWTNQSQVTYCMTAQEDSAVLAVLLRAQLARRADLGRAIVMRAGSNFDRPPPSMTALDHLLLLGQNGFQLAINNTWKAGSRIVAGILSDWDAVYGPGIPAANYLGDVFGSLGGTPNFGPGSVFGGKGAAPDGSTYAGREGGGGDGSAERGGGGGVGKRRGLLGDGGGAAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXU2</accession>
    <name>A0ABR1VXU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009653</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665930.1">
        <property type="nucleotide sequence ID" value="XM_066813968.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047028"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22679">
        <property type="entry name" value="FHA_SLMAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051176">
        <property type="entry name" value="Cent_Immune-Sig_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 170 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715:SF46">
        <property type="entry name" value="TO VACUOLE TARGETING VPS64, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="766"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="4">
        <location>
            <begin position="221"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="574"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="688"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="522"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="635"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="438"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="475"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="708"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="744"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="797" mass="86208" checksum="54D0F877F5DF544B" modified="2025-10-08" version="1" fragment="single">LDPTTLTTPHDRGRKPPTLVQHNRPAWGMNGHGGQTLNQMNPEELNRMFLPRKNIQRTNSSSSLSSNASNSSTSTVLGPNTQQPSQSNAVNGGASMSAAGDLSSWPNATGARKRPQGKAPWPSSKPEGQSDFSAARLSARPQMMPGSANGGPVGGGLNGSSSMHSPSPILQSQGQMANQSGMPRPMTEGAPSGGQPVLYLLSLNGTFERKTISVPFSPDTLRIGRQTNAKTVPTPINGFFDSKVLSRQHAEIWADRQGKIWIRDVKSSNGTFVNGTRLSQENRESEPHELQTGDHLELGIDIVSEDQKTVVHHKVAAKVEHSGFLNASNNLLDMNFGDLDPANGSMMMQPVGGMPYRGRNGSQASMANNGRMMPAGGMMAAPPNGMAHQRGGFFFSPISTEQIVKRLQSEMRTARLQTQDLGRTNQFISTLLSHDDIKDMDRLEPAEPPKPQMSNGAINAMPFLRNDNKARFSDPPAPPPQQPLPEKPDVPSLKRGTTEKPKVPTPNSGASPIRQDGNVSQILQLTEALNGARKEIESQTSRMRDLEEMLQHERQARELAEELARRLEDAAAAKVNGASVKPEENQSTLEQAFEPPVENSSSPDVEMTTGESDVKSLPPQVDAMEASATHLHTQLETMVSEIKDLKQQLETYKQRAEVAEMERDADRQSLAEMALQIRKDAEAREALVREKSRSRSNSQELHKFETGSVASDESTLIRTPSTSSSGGQATPGGPSDPPTLSRASTITPSTSSTGGLSRDQVLAHGLPYTSMIGVVLLGMGLMAYINGWQPQPSRLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8K5</accession>
    <name>A0ABR1W8K5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_007632</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667289.1">
        <property type="nucleotide sequence ID" value="XM_066811947.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045007"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16630">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058758">
        <property type="entry name" value="UBA_RNF216"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF42">
        <property type="entry name" value="FINGER PROTEIN (ZIN), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26191">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26112">
        <property type="entry name" value="UBA_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="419"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="277"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8079814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="653" mass="72759" checksum="D89BD8760AF566AC" modified="2025-10-08" version="1">MFLPTFLNPSGSRSSSHKSKSSKSSPETTPVRSRSPDPSLADYLYDESQLEPPPPLPKDLLDLNTCLEILATIFPDVQVEVFREMLASFSEESRLEVIADAMLKNPAAWVKGRRRLRGGQKEGEAAIYEPPVPPAEAFRGSDYRNAVRSLAWQEFKGLSKSAIDAVLSESNYSYLDARPTLVNLSSKSWKFTISSMLFRRKPVTTGEAENHPLVVWKSSGQGYIVPTIKPTGNAELDKELFNELIVPLKKREASTREESDRTLAMTLHTEEAEAAEATYECACCFTEATFEEFTTCNTSEGHMICFRCVQHSITEAIFGQGWHRSINKDAGTLHCPAVASQECKGCISAQHIHRAMLQERNGAEVLRKFDQRLADHDLLSSNLPLIRCPFCNYAEVDDLYVPESAQKRMRLRVNNLPNLIFLVVITLCVFPVSVPLIMITTVAVFFLSSIGVARNYAIGAVTDSNSYAVTRSVGQASCMSCSKGWVDIHVCHESELVALRTAVEQAMSLAVKRVCPRCYTSFVKSAGCNKLTCPCGYKMCYVCRADIGASNQGYSHFCQHFRPEGDGRKCLECRKCNLWEAEDQEAILRQAREDTERKWRDENRDISAAERAYLDTGVASGGAGKTMHKVLTTGRLPSVNDVFDFFVETFLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAE7</accession>
    <name>A0ABR1WAE7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleic acid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008279</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EIF1AD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667936.1">
        <property type="nucleotide sequence ID" value="XM_066812594.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045654"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039294">
        <property type="entry name" value="EIF1AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641:SF0">
        <property type="entry name" value="RNA-BINDING PROTEIN EIF1AD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="25"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="135" mass="15368" checksum="A46727D6744BE770" modified="2025-10-08" version="1">MGRPKRDIRAAAEEAMTPPDTLSENQSLARVIKAEGNNMYSCLLPSRKNVVVELADRFRNTIWIKRGGYVLVDLYPTPEAKSRAEGGISNIVRDEKAWRKQSYWPKEFAKNTYDDEDEDESNVGKMPPSDSEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAG4</accession>
    <name>A0ABR1WAG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">acetyl-CoA C-acetyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_008295</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667952.1">
        <property type="nucleotide sequence ID" value="XM_066812610.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045670"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF156">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0630">Potassium</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="13">
        <location>
            <begin position="40"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="14">
        <location>
            <begin position="308"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8080477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="403" mass="42474" checksum="7096339A869B053B" modified="2025-10-08" version="1">MVLLARPATRACLHSAARYPSAIRHFTAQAALRQEIRDAYILSAARTPTAKFNGAFLTVPAPKLGAVAIKSALEKSKVPAEKITDVYMGNVLQGNIGQAPARQASVFAGLPSNVEAITINKVCASGLKAVVFAAQNIQLGLAEAQVAGGMENMSQVPYYVPRSSSLPAFGHVKMEDGLIKDGLTDVYDQFHMGICAETTAKKHEITREMQDAYAIQSYERAQAAWKDKAFADEIAPVTVKGRKGDTVIDTDEGYLDVKLDKVPTLKPAFIRDGTGTVTAANSSTLNDGASALVLGSKAIAQEYGAGSRVLARICGSADAAMDPVDFPIAPAKAVPIALERAGISKDQVAVWEFNEAFAAVIKANEKLLGLENARLKPGEYGVAAICNGGGAATAIVVQRIESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAI3</accession>
    <name>A0ABR1WAI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667990.1">
        <property type="nucleotide sequence ID" value="XM_066812648.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045708"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="621"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="155"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="344"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="484"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="654"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="688" mass="80210" checksum="3243719D489DB4E9" modified="2025-10-08" version="1">METPTHYSSNHHTDMLPEKTGHSVVQSVEVTPEMELNGSTLDRSRSPELGNGFSSSTSMAIHPFKRSTIRSSSPTGSVRSSSLSTSRRHLVSRRFSGGSLMRSHRSEVSKELTLQGESEFFALMELMSNISRRSNSLKDVWMKLISERESCLSEMDRMQEQFEEYTEIIESKEKEQTQHQHDHEEKKKEVSRLRLELSTVLASVNEYKKKLTDRDTDLDNTRRELHEYKEMSTRFRTEHEEMKRSLEATQLKLVSSEEERSHARKDAEKHHGDLRSLNQKHAELHTGFTQLTSKHESTHKELVSLKQAKASLTKEKHEWLHMKSELDESLRKANHRGNEFSTKIEELTKSHEKKVQEVHKLKQTVSKIEYEKDELHQSLEDLKRKADERHSKWEDAEDRCGKWKVKWEHSERESASIREEVRHFEAEKTELREALSKKVEELRLVITEKDRVNGDFHAERKKSEEHHRKITLLQETIRRHEASIKERTESIRSLHERVERLEIERDGARSKCGDLTIEIEQLRASIASLKVEITAAHEEHDVACEKLRESEARYEEACVTMSEYTEGHGNFEYEVTTLRTMLREAREQKEKAIEARNSADHERDASIARYEEKCRELERFEEQMSEQMRAQASSSSSGGSRTVRRFFSRSSTSNEMLRSSASHDMLRSSVSNDMLNGSSRHISGNIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAQ7</accession>
    <name>A0ABR1WAQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668054.1">
        <property type="nucleotide sequence ID" value="XM_066812712.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045772"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="114" mass="12309" checksum="D255000BE4D04B13" modified="2025-10-08" version="1">MAESSRMRYRPVGKRLDSDCEGSAAWPSVTRHVKRGIISDPGQPWPDHGDAVLPVCSMENLEMRNRQRVGLANGKACIANDVAQISNQALEKNPKRLDAPPDVGATMPAADCGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAX0</accession>
    <name>A0ABR1WAX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668111.1">
        <property type="nucleotide sequence ID" value="XM_066812769.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045829"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="918"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="927"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="951"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1059" mass="115525" checksum="5AC99A44DB1BDF90" modified="2025-10-08" version="1">MLSSPSCCVVLYCDIARYNGLEKGFRSGTISRRRHPLLDRDSLPDTGTSTVESNPWPSRRRSSSSLSTASRSRASESCMYARGLYYSLLASIICRVLTASSTRQTSGEDCARQRFIVWAAVKRNKSVRMAHSERLRCPLLRCGEQFNNHEDMLGHLTDCRHFATGEYVCYDCMKVERYSEEGKCKGCLAGHPTTKRRRMIQKAKTFFSTLGHRSRKEEMVEVVADDAMPSPPSYDSLDIPQEPIEPEPQQPTIEIEMGGTEILEMDSSSQPLQLDSVNYEAQPAVSNESFPSNNIDSMIAPAIGLTGLNSSPGCCRPSLALDTQNVGRRPVKRSGAYLTPSSSLRSANSSISPMSAGSLAWTLDSSINTNLTSPITPFSPDEIESSALSRENSCKFPKDHPTIVCWDGAVGDGVSDKTVLLQTSLEAEVDDGEYALGNISELPGDDPLSLSMPRAWNNEPLFDFDQEQNFSWSSSIDTEINVLFTNNNQSGEVPPPQMAQEQHINAGSETQALVNAVWDTLREHVTSSVAKTGPSLGGNLLAQELRSLSAKQVALKGLASLRGILGGLDPEKPIDYICFVHLAYALSLVLHEDDLSNRCKQLFQQAMAYQGFLSADQRGVFCQLVRAIWQPREATHSVQQANSTFLTPDPKGKSPEFRCNTGTPTGADPLVGVAQNFLDDLEAIIISSALDNAGSIGSIEILTSDLWTMHISDNSRPQGPKPTDAFVITVDYITRILSQNFGSQNDALASRLRALYNKVESGYITSIRRLELEILQAGKIGLARLTFRQSVLPTSQFSDAYTRDVRSLCDPIYTQQGLNSRSRYHTLGVDLVESLIRGVPDEPPREDIGSFSVPDVFDEFLHSLDEDFVGDNPDFLIPTEVSSVLEGSAIAQAPQASTGAPAFDSTVNPTILGRRNSSIAANNNMPSGQESGSMSSVTSSMQSAAEAVVSGNGGPGGEEGAGSTAAQQQHKVEANSCCEICGYRPKGDPQWFKGSMAKHKKLQHSTDPPRIYKCSYPGCTSAYKNRPDNLRQHQIEKGHFVEGVDSTGRPAKRKKTSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBF2</accession>
    <name>A0ABR1WBF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CoA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667837.1">
        <property type="nucleotide sequence ID" value="XM_066812495.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045555"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33303:SF2">
        <property type="entry name" value="COA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33303">
        <property type="entry name" value="CYTOPLASMIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA-binding" evidence="1">
        <location>
            <begin position="10"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="156" mass="16261" checksum="F2A957B668047924" modified="2025-10-08" version="1">MTTEATAKAFFSSPYFSVVGASSNPAKFGHKIFAWYIAHSIPATPINPGSSSIAISGKDYATVPTLSALPHPKETSVSIITPPAATLKVLKEAKELGIPAVWLQPGTFDDEVLKFAYSKGEDGYGGEVVAGDGGRGSEGWCVLVDGEKAMRAAGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBJ6</accession>
    <name>A0ABR1WBJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008696</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668353.1">
        <property type="nucleotide sequence ID" value="XM_066813011.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046071"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="591" mass="66752" checksum="1747869606520BAA" modified="2025-10-08" version="1">MDLLACAAFSLAEVQLAKSLSMTRTETPQLASIAAILFLGQYLLLKFYRVFLYHRYFSPLRHLPGPTDNHFLFGQSINFMRSESPTGLYVKWMKQWPDAPVIRYLGVFNREVLVVNSPTAYKHLLQNNCYSFVKPGWWRKAVREIEGDGLIMMEHDEHRAHRKMLNGTLSAPSVKKLEPVVWEKAREVGLLFDSAIAADPSGNTGIISSSDTFSKFTLDIMGRITLGFEMNHLGSTAETYRQGKLEKSPSSRSKQPVLSGDPTFHEAYMAMFGQSTFGNLLTFVNAFFPIRWLPLEANRLYLRGTSWINRTLSSIIRKRQEEVTRATEVGSYEKENSRDIITFIAEETLPGGPAAGLKDNHFLGHILQLMAGGVDTTANMIAWSSYVLAGHHDIQARLQGEILDFLSRVPEPTYPDIDTLPYLNGFVKELLRVHCPGKNFAPFISSIAHTLLIIPPTYHLLLTATTIHRQALHDVILDGVHVPKGTEVDAAFAMPMTNPLIWGADADQIKPERWSHLTTEQKSPYAFPAFSSGPRMCIGMNLAYLEMKVVLVEIMRRYRFVEVVQEPRLQSPSFLLHANGLEVRVERIDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBK3</accession>
    <name>A0ABR1WBK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668371.1">
        <property type="nucleotide sequence ID" value="XM_066813029.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046089"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="5"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="35472" checksum="E100DD8419E58719" modified="2025-10-08" version="1">MTPPFDVILRSRPITFVIGPNQTEFVVHADALTRLSAPLRVLLDGDMKEAQEGRVVWDDVDDQTFVRFIQWAYTKDYVPAKPDILLDASDIELDGEALVSTHQPERALYSLRDKAVGAPAEHRTCPKGSNYTTHLRPQTCPGCSENFNGRKCTSCKFQVDEYCPECRITRKGTAMAKGFLARTDWSMPETPFKPRGNSDPCDDYSVVFCSHASLYIIADKYDITALRDLSGHRLYQTLKTFTLYPSRMSDILALVALVFENTRDEDEMRSMIVHYCACIVEDLSKCKDYRPTLVNYKEFSSALMVKMSERLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBZ6</accession>
    <name>A0ABR1WBZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008345</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668002.1">
        <property type="nucleotide sequence ID" value="XM_066812660.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045720"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16630">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057414">
        <property type="entry name" value="Zf-C3HC4_IRF-2BP1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF47">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25454">
        <property type="entry name" value="zf-C3HC4_IRF-2BP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="249"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="471"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="534"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="560" mass="62513" checksum="5885F58C5D9855B8" modified="2025-10-08" version="1">MSNPVNGSLGLMAEVIDLVDSESDDGPGNSDQVSMQQKQTCLAHVLSVFEDICPTHLAGLAEVHNHNAEYIVALIVDQQENGTPYPKRENTKKRKRAETNSPAVEESAAIRAKLHDPEYNRIMTTSRYKDMAVILISQDYPKVPKNTIKNLLAQHGSSVFHTYTTMDEAARNWNPAAPLWIEKKTATKLEVKYSRQNIEQLLREDASDGELAALKEFVAARRVREEHEAKAAAEAEENANMDRAITSGQVAECGCCLDDVPLNRMVQCDGEEAHSFCRPCMKKQAESQIGYQKYQLTCMSMEGCQAGFSASQRKTFLDEKLQVALDRIEQQAMLEMAGIESLETCPFCPFAMEYPPVEENKEFRCANADSATEEGHEARHTIEEAMSEAIIRRCNSCKNPFIKQDGCNKITCTRCRTIQCYVCRQTVKGYDHFNDATRGGKEGQCPLFDATEERHEAEVQRAQEEMRKKVAEENPDLDNTALDIKVSNKVQEDDKKRKERDPVNAAPLRPGQANAPGPGVQMGQADGPRPEAQVDQNNGNPRGNSDKGTCMQRNERISTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WD86</accession>
    <name>A0ABR1WD86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667609.1">
        <property type="nucleotide sequence ID" value="XM_066812267.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045327"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="339" mass="37853" checksum="38355EA73422B181" modified="2025-10-08" version="1">MSASGSAESLISEAESNATTLYASSSTSSSTRTSVSSRSSLASLDYSRQQLHHQQQQLQQLQQLQQLQQYYPPPPQYQHYPQQQQYGAPLAPVLEEQHLKLMQQAARKQIARDERLPAGGESHESRWSPSGVKWRYARQGQHLTAIASEELDDASFERRSYIDGVAYYLRACPDNLNELETDILLRSAPFLAERPRPTRRIAIRRPTDRGKTFLHRGVQQAVALAMVALHAIWCAVLIMGRVGVQYERQYKLSSQIVAHGYWFANSVGKHSVHLSARLQKAGDGKVGQIFSGLVAWTMESFTGGIQDGYGDGMVMIQGQTGAGAKKAALEQEYLHEHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WF59</accession>
    <name>A0ABR1WF59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Mitochondrial fission 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_008551</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the FIS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668208.1">
        <property type="nucleotide sequence ID" value="XM_066812866.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045926"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12212">
        <property type="entry name" value="Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016543">
        <property type="entry name" value="Fis1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033745">
        <property type="entry name" value="Fis1_cytosol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028058">
        <property type="entry name" value="Fis1_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247:SF0">
        <property type="entry name" value="MITOCHONDRIAL FISSION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14852">
        <property type="entry name" value="Fis1_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008835">
        <property type="entry name" value="TPR_repeat_11_Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8080733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="151" mass="16990" checksum="CE63229FBE1C7543" modified="2025-10-08" version="1">MTALPHAVDAETPLKPDELQVLRSQYEKEGDMVGVQTKFNYAWGLVKSNSRNDQQTGVQLLSEIFRVSPERRRECLYYLALGNYKLGNYGEARRYNDLLLEKEPMNMQSADLRRLIDDKVAKEGLMGVAIISGVAIAAGVVGGILFRGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLJ7</accession>
    <name>A0ABR1WLJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668885.1">
        <property type="nucleotide sequence ID" value="XM_066809962.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043022"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="100" mass="11351" checksum="C986725E1CCF4031" modified="2025-10-08" version="1">MCPPNGRLNLMDRRWCTPRPGQTMPIPHQSSTDTLIVAEIEAERQREFRQLICNTTAARDGAGDETTRKQWQITIDELKSLEAPTCRSPGDHGHREQAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLK3</accession>
    <name>A0ABR1WLK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668883.1">
        <property type="nucleotide sequence ID" value="XM_066809960.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043020"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="23629" checksum="93B41E16062F1F4E" modified="2025-10-08" version="1">MAPRKGDKKEEEKKKAKPKPKTTTPKATLRAKGYVAYTAKGFRGELVDRGRYVKCQLPVRRVDLNQPNHRICGATIQNEKRPIQSHYRQAHEVDSARDRDTKKDASRPWTCPCGADHENWTSHLQHIRKVHGVRGVTKAIREAGGLLKSGARLDPKTGLVKAKEEEEEEEDDDEGLFVPPHQDGPRDPKFDDDDHDGGFGPSGAAGGLIEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLS8</accession>
    <name>A0ABR1WLS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_005738</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668976.1">
        <property type="nucleotide sequence ID" value="XM_066810053.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043113"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19473">
        <property type="entry name" value="SET_SUV39H_DIM5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050973">
        <property type="entry name" value="H3K9_Histone-Lys_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223:SF3">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SET-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
        <property type="entry name" value="Pre-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50867">
        <property type="entry name" value="PRE_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Pre-SET" evidence="9">
        <location>
            <begin position="76"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="8">
        <location>
            <begin position="164"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="10">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8084467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="37814" checksum="A134746E0F3B5C5A" modified="2025-10-08" version="1">MEAATQQHFFVHGRPGRVAEKEKCHLCQIRSFTTHTDYPVTITNDADEQVLEPGFRFVQNSQLGRGVQSAKGEFRSGCDCQDGEDCQYTSCHCLQELEESEEEPDDEDGIIYRRKSYAYHSHGAKAGHLRTRILESREPIYECHEGCACGPECPNRVVERGRKLPLQVFRTVDRGWGVKSPVDIKKGQFIDKYLGEIITPKEADRRRAKSDIAQRKDVYLFALDKFSDPDSPDERLRGPPLEVDGEFMSGPTRFINHSCDPNLRIFARVGDHADKHIHDLALFAIEDIPKGTELTFDYVDGVDDTEVDALDPAKKKDMTLCLCGSRNCRGFLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMI9</accession>
    <name>A0ABR1WMI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669246.1">
        <property type="nucleotide sequence ID" value="XM_066810323.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043383"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39401">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39401:SF1">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="29"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="168" mass="17687" checksum="C6F56D8F1A74E911" modified="2025-10-08" version="1">MELSHVIASWPLVGAAAASDVEPAFSSYLKELYASAEDTSATETFTDFFTPTGQLLVLGHVATGADAIVALKQQLLPAAGAKHWNHLPNATTVDSETAGQKTYQVLGVIETRFDGGNCSQAYYSSRFTVTRDAAGAAQLAPHTGSLVAYDDFVVDPPESPTHIPCGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN10</accession>
    <name>A0ABR1WN10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonuclease H-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669408.1">
        <property type="nucleotide sequence ID" value="XM_066810485.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043545"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Piwi" evidence="2">
        <location>
            <begin position="694"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1034" mass="114363" checksum="9DADA106E1D52562" modified="2025-10-08" version="1">MSDRGRGQFRGGRGDGGFRGRGDGGGYRSGGRGDGGGFRGDRGGRGDGGAFRGGRGDGGGYRGGRGDGGGYRGGGRGDGGGFRGDRGGRGGSASFSGFRGGRGGGRGGRRDKFEGEGEVFGGGKFPQPDANVTKLEDKLLNDLKLEAVTHKMGSMDLSSGEAGSSLPLKHIPVRPAFGNKGKAVVVATNYYEMSVQPQTLLQYKLTPTRIWPPGVTPRKTEPKGRKLHRIIQLAMEKLQGVWVSEFKDYVYTLNPLSFPDGNTTVRIEYADEGRPMEFDVKFDKTKSIDVDPLVKYLTTLKDYSGDFPVYADVVAAIGAVLGHTPRSSNNVASLGSSRHFPLNVPGQSSSLGFPDMNIIIRGYFQSVRPATGRLLLNLNVSHGVFRFAGPVKQLLEQYNDSQLRYVHRLLNRLRAEVVFFFDQGQPKNVKKAKASGPSQDKIGRRTAEKTLNGLATRFDGPKKSNKITVQRDFARPSEVSFVLDGDVPSGFKQGEKYTVAQYYQIRYNCTVEPNLPVVNAGTREKPIYIPAEFVTIKAGQAVRRKTTPEETREMIEFACRSPFANATSIATLGRQSLGLDNSEVLKAFNVAVGKNLLTVQARSWNLQNVKVFKSGLSIERCTWVNIQQDWTGRHYDPNELKDTMEEWRKFMQDKMGIPCKPFKHPTGLQIRLGRGQHPEGIIREAFKTIEQAQMVFVVLPGKGADIYNAVKLVADSEIGFHTVCVVRDNLLKRQPQYYANVGLKVNLKMGGANHKLREDVPIFKEGKTMGLGYDVTHPTNIAGSDKLPSIVGMVSSTDRDLAQWLPTTWTQKGGQEMLDDRLCEEFIGRLRLWQKANNQQLPDNILIFRDGVSEGQFAQVLTNEVPQMRKACSKVYPANRKPLFTLVVSVKRHQTRFYPTETKNMTKSRNVKNGTVVDRGVTLARTWDFFLVAHTALQGTARPAHYTAEAANMMEKVVHEMCYLFGRATKAVSICPPAYYADILCTRRRVYMSDVFDASIDDATSVSSGSQEQHIEKASGRKIHDRLKDTMYYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN40</accession>
    <name>A0ABR1WN40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669463.1">
        <property type="nucleotide sequence ID" value="XM_066810540.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043600"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00048">
        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="14314" checksum="5BA6AD22FDC56B2B" modified="2025-10-08" version="1">MGGFYMQYLESLCRRRGWQDPSYECYRDASGYTCLVLVNGREYQTDLAYESDGLAQENAAMRAFMVCRNFSVNGGMLARNGIVQGLPANDTGRRHKKSHGSASTGRRESRHHHRSGHHSSSSSTASFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPA2</accession>
    <name>A0ABR1WPA2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T1</fullName>
            <ecNumber evidence="2">4.6.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_006588</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[RNA] containing guanosine + H2O = an [RNA fragment]-3'-guanosine-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment].</text>
            <dbReference type="EC" id="4.6.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease N1/T1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.24" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669826.1">
        <property type="nucleotide sequence ID" value="XM_066810903.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043963"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00606">
        <property type="entry name" value="fungal_RNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.30">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="N1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048269">
        <property type="entry name" value="RNase_U2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42104">
        <property type="entry name" value="EXTRACELLULAR GUANYL-SPECIFIC RIBONUCLEASE RNTA (AFU_ORTHOLOGUE AFUA_4G03230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42104:SF1">
        <property type="entry name" value="EXTRACELLULAR GUANYL-SPECIFIC RIBONUCLEASE RNTA (AFU_ORTHOLOGUE AFUA_4G03230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037430">
        <property type="entry name" value="RNase_U2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045363315" description="ribonuclease T1" evidence="10">
        <location>
            <begin position="18"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8085317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="130" mass="13585" checksum="81C135A8F43CB32D" modified="2025-10-08" version="1">MQFILALVPLLAAFATAAPAAAVLEDRAATTCGKTSYSAAQVNAASQQACTYYKNNQQANSYPHTYNNYEGFNFRVAGPYQEFPIKSSGVYTGGSPGADRVIINTNCEQAGAITHTGAKGNNFVGCSGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQW4</accession>
    <name>A0ABR1WQW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 2 beta subunit protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_006131</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669369.1">
        <property type="nucleotide sequence ID" value="XM_066810446.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043506"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor IF2/IF5" evidence="5">
        <location>
            <begin position="202"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="37"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="328" mass="35939" checksum="308B34D3A39D69D1" modified="2025-10-08" version="1">MATEERPISPDRKSRKSVVFDTEAVVVEGDGTVTKMASAEAAQDTAQSHAPSTPPLSDALGAFTNPNEAPVEEQTPAEDGLDLSMMKKKKKKSKKTEDADGEAAAEGAADEGGLDLTMKKKKKKSKKTEEDELAAKIAALEMGEEGAEDQAEEPKEEQTGDMDKGTGIWTHDETKPISYELLLSRFFNLLAQKNPDHASSGSKNYKIPPPQCMREGNKKTIFGNLPDICKRMKRSEEHVTSYLFAELGTSGSTAGAGQLQKQIENVLRKYIIEYVTCKTCRSADTELNKGENRLYFINCHHCGSRRSVTAIKTGFSAQVGKRRKMRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRQ0</accession>
    <name>A0ABR1WRQ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-rRNA-processing protein TSR2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TSR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669533.1">
        <property type="nucleotide sequence ID" value="XM_066810610.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043670"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019398">
        <property type="entry name" value="Pre-rRNA_process_TSR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21250">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10273">
        <property type="entry name" value="WGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="146"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="209" mass="23444" checksum="63184FE54313267D" modified="2025-10-08" version="1">MISFSPETRQENFEQAVALSLNLWPALTLAVQNKWSENAGDDPEDVRAWFAGAMIELFPDFVKLAAFETANGDKKKKPADLEEPDLEDVEGRLLQVMEDEFTVVVDDDSSYEVAQQIVGLRAACIKSQHATIDEVEQLRQRWVSKKGQKVAMQQGPEQDQETDSEEDDSEDDGEDTNMDEAPALVPTAPKEKPQPEIDEDGFTKVSKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRZ8</accession>
    <name>A0ABR1WRZ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670224.1">
        <property type="nucleotide sequence ID" value="XM_066811301.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044361"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="36873" checksum="EC57FD65733370B4" modified="2025-10-08" version="1">MSITKLEAQVDDMPKDANGMFKYILKQVASENRVSAAFYLRVFMVVGSGRPVALYEAAARLVEEQDYVNSGLPMASEGYGQRIARLTGGLLLPVEDSSDDRFREVMKPILVNVFEFLKRPSVLKNLEQKGLDEMTKEVLSLASAWEQVQPPVEYQLLDELDRFNTVRYGTDPHWLNLTLPFAIFGPVGGHEETFLAIAIEYDLVSYVGEVVRNRPDELFAKKGRPYLDYALRRDRANFRMVRLLLAAGLKPNEPFHVLELAIRAPPLGGDTVWSVFLQHRLVGKTYNTADGDALTDLLLEYGADENIKAKYDQEVANRAAREAFVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWQ5</accession>
    <name>A0ABR1WWQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002556</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670489.1">
        <property type="nucleotide sequence ID" value="XM_066806871.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039931"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF91">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="195" mass="21650" checksum="768E4F930ADB8A93" modified="2025-10-08" version="1">MASPTASESKIEAQRDGPDVANSAVLPAYGDAPYSAVDEKKLVAKLDRRIVPLVMLSYTLSFLDSCFMVAMGLYIVFSPCRDSSTNEELRSCPTTAPRYGKRTTACGMNLTIGNMSGIMAPFIYLTGEGPRYIRGNAVSLSMVGMAVGLYGFLWFWFRRENKRRDAGQVSAEHAHLSEEELMELGDESPHYRYTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY76</accession>
    <name>A0ABR1WY76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U1 small nuclear ribonucleoprotein C</fullName>
            <shortName evidence="8">U1 snRNP C</shortName>
            <shortName evidence="8">U1-C</shortName>
            <shortName evidence="8">U1C</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003056</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the U1 small nuclear ribonucleoprotein C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670989.1">
        <property type="nucleotide sequence ID" value="XM_066807371.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040431"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03153">
        <property type="entry name" value="U1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013085">
        <property type="entry name" value="U1-CZ_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017340">
        <property type="entry name" value="U1_snRNP-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148:SF1">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06220">
        <property type="entry name" value="zf-U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037969">
        <property type="entry name" value="U1_snRNP-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="10">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="65"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="14872" checksum="48F41D035AFB2969" modified="2025-10-08" version="1">MPKFFCDYCDVYLTHDSMSVRKAHNSGRNHLRNVVDYYQQIGHEKAQSVIDSITSSYAAEGQAHANPMLPQNQPHAAHHHMPHHGAPGSGPPPLPMPPGAGAPGFPPMPPRESVVCPSLCPPACRLCPVCLAAPRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYW6</accession>
    <name>A0ABR1WYW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PLL-like beta propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671253.1">
        <property type="nucleotide sequence ID" value="XM_066807635.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040695"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.70">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058502">
        <property type="entry name" value="PLL-like_beta-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26607">
        <property type="entry name" value="DUF8189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89372">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLL-like beta propeller" evidence="1">
        <location>
            <begin position="168"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="393" mass="42480" checksum="A2EE5E99452634F3" modified="2025-10-08" version="1">MAGGPGSPTSVAPGFAPTAVSRGYPHLEVFAVTNSMENSVYRKYRNSNATSAADFLPQGLEMELVGGGVDRDKTPSISVSWRHHVEKGVPTNRTELHIAGVFDTKVFRKYRDQDGAGGWSPGGTGQWDVFGANQWASSPVQVRYGPETSLMGAFYLCRAQPGLGVCFWQWTPENNWSLAGNPIAGKSDLQPWAAPAVVAWAGDDRRLDVFVVSRVNNHLMHTWRDADNPGEWALYEDLKGFVTTPPVAVSRAPGLLDVFVRGGDGGLWHLGFQEGKWSEWELLSGPDVKIQGQPEAISTSADTIDVFAWGTKGELLHKKFDNSSNSETKWTPASGFDTVLDQGLSGPPRAVTDGTGDIHLLAYNEVDNIILSTLSSKPGVKAEKTVIAAVPMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYX2</accession>
    <name>A0ABR1WYX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">protoporphyrinogen oxidase</fullName>
            <ecNumber evidence="5">1.3.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_003322</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:25576"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.4" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671255.1">
        <property type="nucleotide sequence ID" value="XM_066807637.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040697"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF3">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="13">
        <location>
            <begin position="107"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8088361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="727" mass="80816" checksum="BB44088662263496" modified="2025-10-08" version="1">MTSKRPEELFIALLRSAYSNGCRHAVSGARPARALPQLTFLRAQASYSRGFATGRARLPYVPKSLLSRSSRSYATAATPPQPQANTDVQSPPSADPPRRIAVLGGGITGLTAAHYLARHAKNAHITLYEGGDHLGGWIKGEVAKTAEGEEILLQRGPRMLRSGASGNKYDDLVLYDVLANLELGDKIVYPKGTANSRYLYYPDHLVKLPSEEFSLNNILESVQSFLTEPIWEGTFGAGLHMWKHSIETKNKRDHRELEIRTALMRNEPMPIIDTSVLDKDESVADYLLRTMGEDRLIKNVVSGMLHGIYGGDAYKLSAKHTIFDRFWYKDQSLTRDGEIWMAVKDVFLPYDILDSPNAYHVIDLAERGIQHKLIAFEDGLLTLVRGLVDDLKEWANVEIKRNTPVTALAHKDGKVLVSAEGKTEQFDQVLSTIYAGQLAKIAQPANSLPSLSEVPAVTIMVVNMWYPNEDLLAANPGFGYLIPQGVSEEQNPERALGVLFDSDIQTRKEQAGTKLTVMMGGHQWDKWAFLPDEQMAVEMAKNVVQRHLGISPDEEGLVASARLCRDCLPQHTVGHRDRLRKAHYELSSAFQGQLMVAGPSYTTVGVIPAMRAAYDAAMRMARGQGAPHFRNKEQGVGVWNWYFEMLDKLKVTPSIPDHVGTTGLEWATESDAKNMVPVPRASMRFKSWTPESNRFIDEDGNLKPGSVEALTQKDGIKNSQLFQKRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYZ6</accession>
    <name>A0ABR1WYZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671254.1">
        <property type="nucleotide sequence ID" value="XM_066807636.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040696"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="173" mass="18714" checksum="5989E6E26D5C0F42" modified="2025-10-08" version="1">MANDAHDQSRGPEPGLEVVQSEHSNASSPQVVHRRSGESAPEVALPDHAWIYPVHDANEQQKVLPSGLLQQQIHQRSARGQQYSHDYNAKYPSLRGNHFLTTPEVVPNSAAGSFSAGSEEDGGYQSPLKEASLHSPPRKRPRRQIIILVVVVAVILVGSTVGGVVGALRSHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ23</accession>
    <name>A0ABR1WZ23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003377</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671310.1">
        <property type="nucleotide sequence ID" value="XM_066807692.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040752"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33428:SF14">
        <property type="entry name" value="CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33428">
        <property type="entry name" value="CHLOROPHYLLASE-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047326165" description="CBM1 domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="3">
        <location>
            <begin position="21"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="308" mass="31897" checksum="601072224C0078AD" modified="2025-10-08" version="1">MGGKFVCTLIAAVSLAQGTVAAQPVWGQCGGQGWAGDTTCESGSACVSQNPWYCSGGGGSQTTSVAATYSVDPTLPDHTIYRPVDMNAFDKMPVMVWGNGACSANSLSHQNFLLEIASWGVIAIVSGTPNNGGGTTAQQMTNGITWAVDNAGKGTYAHMDTSRIAAAGMSCGGIEAYAQAFDSRVTTIGIFNSGQYDAGGTNNVLPRLTKPIFFFLGGPSDIAYNNGMRDYAAVPAGLPTWVGNYPVGHGGTYGDPKGGKFGTAGQHWARWVLRGDTSAASYFTGSGAQQDGWTVESKSLNNLQTTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ73</accession>
    <name>A0ABR1WZ73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6536 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671318.1">
        <property type="nucleotide sequence ID" value="XM_066807700.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040760"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046623">
        <property type="entry name" value="DUF6536"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35395">
        <property type="entry name" value="DUF6536 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35395:SF1">
        <property type="entry name" value="DUF6536 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20163">
        <property type="entry name" value="DUF6536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="531"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="575"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="641"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6536" evidence="3">
        <location>
            <begin position="83"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="820" mass="88795" checksum="3FFD0619B5C4FB32" modified="2025-10-08" version="1">MATWEPVPQTEQRPVSRWSEDNDPPATTSHNFTSYIPPYRLLDRFRESPVFGSRGSGHQHQHDDKRGTTREALDDFMHRVRGWRTGIVLCILVCALVFALNAATTVLAVLRIVQGGGGGGGDGDGDGENNNDDNVQQPAADINNEVVTFYQGDCATARTFSIILRLVVNILATILLACANYCMQILVSPTRGEIDLVHRKKRWLWIGVPNLTNLPYVGLNRAAIGLLLIISTLPLHLLWNAALAETISANGFADGSPSLCSLGALPILQYSVLGANALMLFCFVATWFAVRREAKYESEERIVTNGDLIASYLREPDLRFAGRCLASARLVMKAKRQRNHHQQPRRRRGRRASAMTQGAQVGMSDGRIGEEKEEDEEDTAVGFWNSTQPMPLPWNGRSRRRTTVLGSHERAGFTLEPGVNVPGSRRSRLGCFGQEPEDEQAAAMEEQGRKSAPRWHKGVPNFTIRLLPPILLIPAIIGLFFGFGLESNLSLTSFGQPSPQTIAGVPAQLTENSWGAAATALVAHTPQLAAVYVYATCNAALTAMLAHAEVSRFAVRRGGLRVSAPRPDTAQRSTLHLHLPLHVSLPLVMGCAALHWLVGESLFLLRVGVYGVDGGSLSSSPSSSVPPRTVMMAVGYSTVPILAVAGLLTLLVSVMLAVGWFRRYMGAERMPLFATCSASLAAATCPTSSFFFPQTIAAASAGGVGETKPEAGEIRRSETVVVQRRSRVGSWVEAVGLHTGSGAPGTVGLAQGHPSRDELGVISTPDPIAGSYAYYRVRRFEEKLSEHGLAWGIVDDSEPVHHATFSPGPVLPLEKGQFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZM0</accession>
    <name>A0ABR1WZM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA ligase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671507.1">
        <property type="nucleotide sequence ID" value="XM_066807889.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040949"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010506">
        <property type="entry name" value="DMAP1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056881">
        <property type="entry name" value="Mug62_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22754:SF32">
        <property type="entry name" value="DISCO-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22754">
        <property type="entry name" value="DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23024">
        <property type="entry name" value="AMP-dom_DIP2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06464">
        <property type="entry name" value="DMAP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24919">
        <property type="entry name" value="Mug62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01137">
        <property type="entry name" value="DMAP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51912">
        <property type="entry name" value="DMAP1_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DMAP1-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1604"/>
            <end position="1684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1696" mass="186382" checksum="9F5A3DEA7AB2E40D" modified="2025-10-08" version="1">MAQFDPNLQEKLDELERELEEGDITEKGFQKRRTQLLSQFMVPGEEIAKPTGGLRIHSPDDDVYVSSDGHRGAALAALSSNTPEHGAPFAPPSHMSHADWRPQSSGPPASSHSYGYDHPAGLMRPGGPLAEHRPDLSARDSLFLNAGPSYTMGSDPPTRSGTMVSGDYAFRPETGTMLDSQGYFSDFTGQQASDQTPGAEYGGGAQRYSSSDAFSPTAAMAPPMLTANDLPPPEALQYQLPLEPREVPFAIHDPHDESTAMSAFDNIAAVLRHRGRTTAKLPAYWVLDAKGKEIASITWDKLASRAEKVAQVIRDKSSLYRGDRVALIYRDSEVIDFAIALLGCFIAGVVAVPINDLQDYQKLNLILTSTQAHLALTTDNNLKAFQRDITTQKLNWPKGVEWWKTNEFGSYHPKKKDDVPPLSVPDLAYIEFSRAPTGDLRGVVLSHRTIMHQMACMSAITSAVPNNGPGDTFNRALRDKNGRLIGGGASSEILLSYLDPRQGIGMIIGVLLNVYSGHTTVWLENKAVSVPGLYAHLITKYKATLMVADYPGLRLAAFNYQQDPMTTRNFKKGMEPNFQSVKLCLIDTLTVDSEFHEVLADRWLRPLRNGRAREVVAPMLCLPEHGGMVISTRDWLGGEERMGCPLKLELSDGSESDTDRDEEKEKEEEKSAPSNGFGSLLGGGTTTTKEQVAKNELGEALLDREALKTNEVVVVAIGDEARKKASTEPGTVRVGAFGYPIPDATLCVVDPETGLLASPHSVGEIWVDSPSLSGKIFVLGLYEDRIRQKVEWVEHGHEVAEHRYFFVQHLVVSILRNLSKQVYDCSAFDVYVNDEHLPIVVLESTSASTAPTTSGGPPRQLDTALLDSISEKCMDVLMQEHHLRVYCVMITAPNSLPRVVKNGRREIGNMLCRKEFDLGNLPCVHVKFGVEHAVLNLPVGVDPMGGIWREVVIDDRTSTPLNNFSCITDLIQWRVARQPEELALCTIDGRGKEGKGITWRKFDTRVAAVAMYLRNKDFVFAVHACLNIGAVVIPAAPMDERRLNEDVPAFLHLIADYGVKAVLVNQEVDHLLKTKPIAQHIKQSAQVLKIAVPSVYNTSKPPKQNNGLRDLGITMDPAWIQHGYPAIIWTYWTPDQRRIAVQLGHDTILGMCKVQKETCQMTSSRPVLGCVRSTTGLGFIHSCLMGIYIGTPTYLISPVEFAQNPISLFLTLSRYKIKDTYATPQMLDHAMNVMPGKGFTMHELKNMMISAEGRPRVDVFQKVRLHFAATGLDRTAINTVYSHVLNPMIASRSYMCIEPIELWLDQRALRRGLVMPVDPESDPKALLVQDSGMVPVSTQIAIVNPESRLLCHDGEYGEIWVDSEACVKSFYGSRDAFDAERFDGRTIDGDPNISYVRTGDLGFLHNVSRPIGPGGAQVDMQVLFVLGNIGETFEINGLSHFPMDIEASVERCHRNIVPSGCAVFQAGGLVVVLVEVSRKAYLASIVPVIVNAILGEHQIIIDIVAFVNKGDFPRSRLAEKQRGKILAGWVTRKMRTVAQFNIRDGDASGLENDVQVEAHRASVGSLRSSGIPGASSLRNMEHAPQILEQEEFDHQINKMAELPPAEMSAKSSRPVSTLPPIDTRAAAPSGQGYDLGGFDPRGGDAPLSGRQPSASTPQIRLPSVDGREPMNPVEGQGVEDDWSRDAIMHFNLTGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZN6</accession>
    <name>A0ABR1WZN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">separase</fullName>
            <ecNumber evidence="2">3.4.22.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003590</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>All bonds known to be hydrolyzed by this endopeptidase have arginine in P1 and an acidic residue in P4. P6 is often occupied by an acidic residue or by a hydroxy-amino-acid residue, the phosphorylation of which enhances cleavage.</text>
            <dbReference type="EC" id="3.4.22.49"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.49" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671523.1">
        <property type="nucleotide sequence ID" value="XM_066807905.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040965"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005314">
        <property type="entry name" value="Peptidase_C50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030397">
        <property type="entry name" value="SEPARIN_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792">
        <property type="entry name" value="EXTRA SPINDLE POLES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792:SF0">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03568">
        <property type="entry name" value="Separin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51700">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C50" evidence="6">
        <location>
            <begin position="1867"/>
            <end position="1964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="36"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1278"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1406"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1840"/>
            <end position="1869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2016"/>
            <end position="2050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1841"/>
            <end position="1851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2087" mass="228967" checksum="A175967E52E65EE7" modified="2025-10-08" version="1">MASLTTQADAIRSAITSVQTCTPTISATLKELLQGADSEVAEPKPAKGRAKAAPPTRGKPATAAKKSGRATKQEDERNNDALPPKEKALLATQVINATLKALGEAAKSSPTSVANARTAAPAQPTKAEPRKGLRRSSSMPMTPLQPRTLNRVSTSPTAAKPCRPQTATPASSGCLAMVECTRAAFATLRTLSTSGNITLPELQIETGMSSFVNRLIALSLFEYAVKELRLLKRRLEAVISRGNVKKTKGTVATEATTAARTLSDLFDYPVFDASAPVAQLVVTSQLQALRILYGLKKSSYLDTALPFLRPTHQTSPLVLLIPGPSETPLNRLKSARQLESLAQSLLSLTPSVSANDDGVALEPRLSPSPETSLEIQSIALKARRSTGEASSKCAAANSAFEQVWQMFEAMGLRTSDSSRLLMAAIYQSLGTLSREAGDVKDAIKWITKLRGLTSSKDDSAARCHAVTAQLLALSLKQSPNVDESLINQVLDGLQGPLSGSTTELDDLLTSICQVRKATVGIVLGAGRSNAKPNPTRSLLETLLLQLPRFALRWLGKPPASGGPTKDFLRFEQRRQLLSKYIHHVLDSVLMLVKALLEEENMAWDLMDSVFQDCLVLLENMGDLSVLSSSPSASYHVKISHFYYQQHILLRKKASNPKDFLRALRRSIDAVKQQPESEQTKAQLLAKQERLADLCRTSGRKDDAADALRSIRDSIVREDTVSQITAALASTPALTAWQLSGKTQSLSRTVCTLAKLDPMPCDWTWLLTGSDKTTALEHDFYFIYSTDAKLRKSLEAGEPLVEKLLQSYSSDDFPIRRLRTLAQLLTVNIESRDSIRSWVEEARALSKSLQIGNLGEDAGLARYIPHLKSLTVCLAALFELEVDWKPVQEAVSFWSSALTNTRSLEDLYGQIDNPAQLLTNLQSLSDYARMRGMDSLLESILELTSTVSKLLSQDDPACLVAQNTALCLQYLNVGRSTKAETVLTTSQLLLSRPEVPHEIAANFHLCSAEYQMAIGNYEKAERHLADAHVSGVASMSEKSPRSSRATRKLSIAYASFLQALLVLERGNPDEALRYAKNAVRILYHDWAKLETMKISAGSQGDEPSQVEASEDDCSFNSSVSSASDAVRARTGPEFWAMVYPLFRFVLRLSSVYAHIGMFQETMYYGEQALKIASSTNSANYIMQSQAWLAAIHMKAGSAEKALELASEIKESLAKLEPNFAAVRLACQLSQIYRDTADYAAESELLNQAESMIARLDKQEASGGMDLDKRMSKLTIKDKAPPKTTRLPRSRVTKTVSKATPKRKTTTAAAKSSTEKKPLSAIEDKQLMFMRASILQQRSAALLREKEWSAAVEALQTAGELPRLSADMTQDSLFMAVALIGQSLELMGKDSVYSAVLDSTLSFPTVAGSARDKTLAEKNQSTKASPPRKGRATSHEGPPFLETLRQARDHLLDAHAIAVMNGDGVLVQRVATLLQNTFILLSTTNHSKVSGTSHPAYATCSVEMARNLVWRRERKTLKLDSNKGAKLEWPMPVDASDSRRSSLSLAVDMNKFQKEYIDIIPSSWNVVSVSLSDNKHDLCITKLQAGHSPFAIRLPLERAMSRDADNEVFNFQQGRAELLDIIDVANRTCHDARDMSAKGAKSAWWSERESLDERMKNMLENIEHTWLGGFKGIFSQHHRRSDLLARFQKSFQNILDNNLPSRRQVRGRRTKAPTAPKVSLDPRILDLFIGLGDATMPDCDFDEPLTDLLYFVVDILQFHGERNAYDEIDLDRMVVEITDALHSYHAEAKSSRKSQEQTHTILVLDKSLHIVPWESLPCMQGIAVSRVPSLACLRRSILEQKASPESGASTSESTEQEAEQPREGHHISRKSGTYILNPGADLKNTQSVFGQPLSSLPLSWSAIEARIPTESEFESALTKSDLLLYFGHGSGAQYIRGRTIRKMEKCRAVALLMGCSSASLTAPGDFEPHGPVWNYMLAGSPAVVGTLWDVTDRDIDRYAGRLFEEWGLFARGTFAEEDNNKKSRSTGSQKGKKKTKAAASSSDRGDDEGNASTPASLVEAVARARDACKFRYLTAAAVCVYGIPVYVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZQ3</accession>
    <name>A0ABR1WZQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tyrosinase</fullName>
            <ecNumber evidence="2">1.14.18.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_003620</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 L-dopa + O2 = 2 L-dopaquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:34287"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57504"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-tyrosine + O2 = L-dopaquinone + H2O</text>
            <dbReference type="Rhea" id="RHEA:18117"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tyrosinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.18.1" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671553.1">
        <property type="nucleotide sequence ID" value="XM_066807935.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040995"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF76">
        <property type="entry name" value="SHKT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0470">Melanin biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045596502" description="tyrosinase" evidence="9">
        <location>
            <begin position="25"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="10">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="11">
        <location>
            <begin position="305"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="415"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="417"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="506"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8088659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="780" mass="82392" checksum="BEE5586DAA276C87" modified="2025-10-08" version="1">MPPLSKCLRLVAVVLSLSASTVWGQTNRLVVTGRTSGINTATGQRPVRQNVNTLSASAGPQWDLFILGLQAFQAASESDQLSYFGIAGIHGRPYIPFNGVNAVPGGSGGGYCPHGEIMFPAWHRPYVSAYEQVLGTFVTKIAAQYTGSNATTYQAAAEQWRMPYWDWAADAQLPPSASTTTITVNGPTGQVTINNPLYSYKWQKFPLNHANNYFPTNTDYNCWGWPQTTRQPNRQGVDQLAIVNQQLSTDPSPLKDQVYLVMSSVKDFNTMASSGTAGTSFEDPHNDVHNSMYAIMSSLDYSAFDPIFWLHHTQVDRLVALWQAINYNNTVMTGSYQTNGLFATAAGARITADTDLKPFYRDANNFHTGRTAATTKNFGYSYPEISNDWSMSQDQLRTSVIRAVNILYGDGSLAGNPVSSPPSASTATSSPAATSIQPTPTPVQQQAATSQAATTPAQQPTTAATIPAAQPTTSAVSTGSGSGGGNGGGWPWGWPWGWGGWQMFQPGPPSAPPPAKAAAPPPAAKGGPPGKRGKRSTSGSAAAAGQHAKLHRRKGCGKKDVIESPPRPYGEAAAYPTESPALNTTVQSTADANTTTQATANATTTLYALAVQVERSDLPLPCSIIFALGSQTAGQMTVLSMPATGLTHSQIPLKRAIDKLGLTDEIAHDNGPTAITKLTSILQATIRMANGTIVSNPKVPSLKIQVQVQDVVQAESIDHFPIYKEPLKGPTLTTDNSTSPHGADTIALQAPAGLNLTTTTRVSASSAGAATALNGTAAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X000</accession>
    <name>A0ABR1X000_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar complex-associated protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_003672</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671605.1">
        <property type="nucleotide sequence ID" value="XM_066807987.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041047"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011501">
        <property type="entry name" value="Noc3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07540">
        <property type="entry name" value="NOC3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028977">
        <property type="entry name" value="Nucleolar_complex_p3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nucleolar complex-associated protein 3 N-terminal" evidence="8">
        <location>
            <begin position="117"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="CCAAT-binding factor" evidence="7">
        <location>
            <begin position="486"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="332"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="360"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="445"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR028977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8088711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="664" mass="73627" checksum="3FECDE03EDA84D35" modified="2025-10-08" version="1">MASRPAKKRKLTPPPSDDDGRSSAKVQKAFFKNAASWDLEQDYETKARKAQAKVKESTRLPIKLADGRLQHMQATQDDAGSVVSDEDWLDASDASGVEEEEEKPEAPKIPVAQQIREAKEELAKIATLVQEDPEDNAGAFKALAKIGQSRIPAIQKLAMATQLSVYKDVIPGYRIRPQTEDGPKELVSKGVRTLRGYEQALVSGYQGFIKELTKQAKLGRGEAPGKGQTVANVAITCACTLLNSVPHFNFRTDLVKILVGKLSTRRVDSDFEKCANSLIKLFEDDEEGRPAFEAVGLLSKMMRARDYMVDESVLNLFLHLRLLSEFSGKASKDHVEHADGPRPKKLKNKKDIRSKKQKKLDKEQKALQKDMDQADAIVSHEERERMQSETLKLVFASYFRILKAGVPHLMGATLEGLAKYAHLINQDFFGDLLEALKDLIREADAAENGDGEEEEEEQFETKPRNTAREALLCTAKTHTTPGGDLHLDLSFFTAHLYKALLQLSTHPDLELGAKSLHLPDPDAPATAAPKSRNKINLQTTTVLLIRSLTAILLPPWNIRSVPPLRLAAFTKQLMSASLHMPEKSAQAVLALLADVGGTHGRKVAALWDTEERKGDGVFNALSESVESSNPFATTVWEGEILRRHYCPKVREGVKIVEKAMLKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X076</accession>
    <name>A0ABR1X076_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Small glutamine-rich tetratricopeptide repeat-containing protein a protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003741</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671674.1">
        <property type="nucleotide sequence ID" value="XM_066808056.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041116"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052758">
        <property type="entry name" value="SRC_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44200">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44200:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="168"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="202"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="353"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="399"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="437"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="525"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="660" mass="72320" checksum="5D0280DC689DAB9A" modified="2025-10-08" version="1">MKGLFSPKKPSASPSPTKKHATGENDENRSPHANRSRSGSTSPIKTCPSSKADREKARSVRIAHAEHAEPQHTSSQPAPRRVQALVSLIRHERPQFLRQNGRRPGGLGRPSIFPPAKPQPPAKKKVTVPISIPPNTNGTKEPTNDEGPAPPPHRSNPSSPVPTSEDEAESYKAAGNKFFKERDYRNAIIQYSRAVELIPNSATFLSNRAAAYMSHGQYEAALGDCTRAVDLDPTNAKFLLRLARIYTSLGRPEEALTTFSRIQPPASAKDMAQAKEMSSHVRAAQDALHNGTSGSMVLHALDQAEKLLGLGAMKPRKWQLMRGAAHLKIGGINSLGEAQNVAMSLLRFNSQDPEALVLRGRALYCQGDNEKAIQHFRKALSCDPDFRDAVKWLRTVQKLDRMKEEGNSDYKAGRWQAAFDKYSSALEVDPTNRGTNAKLLQNRALCRLKLRQYNEAVADCDRAVSLDPQYIKARKTKANALGQADRWEDAVREWKSIQEMDPEDRTIPKEVRKAELELKKSQRKDYYKILNVEKNADDTQIKKAYRKLAIVHHPDKNPGDDAAAERFKDIGEAYETLSDPQKRARYDSGEDLVDPSDMFSGGGGMGGMGGGMGGIDPEILFSMMNGGGGFGSGEGFGGARFSAGGGGRRPGGFPGGFQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0L2</accession>
    <name>A0ABR1X0L2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome p450 51b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003866</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671799.1">
        <property type="nucleotide sequence ID" value="XM_066808181.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041241"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11042">
        <property type="entry name" value="CYP51-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF24">
        <property type="entry name" value="LANOSTEROL 14-ALPHA DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8088905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="503" mass="56437" checksum="18C161F032F97D8D" modified="2025-10-08" version="1">MGALEELAGPLVQQFTQLHVAAQVGALAAAFIALSVFVHVASQFLFKNPNEPPLVFSWFPVNRAKYGDIFTFILLGKKTTVYVGCQGNDFILNGKAKDVCAEDIYTVLTTPVFGKDVVYDCPNSKLMEQKKFMKIALTTQAFQSYVPIIADEVSSYFKKSADFKGKSGIVNMPPKMAQITIFTASHSLQGKEIRHKFDETLADLYHDLDMGFNPVNFMLHWAPLPWNNRRDHAQRTIAKIYMDTIKERRAAGKSDAQDMMWHLMGSTYKNGTPVPDHEIAHMMIALLMAGQHSSSSTSSWIMLWLAARPDIMEDLYREQMENLGADLPPLQYEDLAKLPLNQAIIKETLRLHAPIHSIMRAVKQPMPVPGTNHVLLSAGGVTATDPTYFPDPDTWEPHRWDKDSPIAPRMVAKNEDEEEKIDYGYGLVSKGAASPYLPFGAGRHRCIGEQFANVQLQTITAMVVREFKFRNVDGSNKVIGTDYASLFSRPLEPANIHWEKRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0Q1</accession>
    <name>A0ABR1X0Q1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671844.1">
        <property type="nucleotide sequence ID" value="XM_066808226.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041286"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051913">
        <property type="entry name" value="GH2_Domain-Containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42732">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42732:SF4">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="4">
        <location>
            <begin position="278"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 catalytic" evidence="5">
        <location>
            <begin position="387"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="668" mass="74469" checksum="D7F4D58286ADE9BC" modified="2025-10-08" version="1">MASSAPPTNYPRPDFVRPNLNWKLLDDQEWQMLYDDQDLGLSAGWHLQGVPDQVEVADASSAGQSEAELQKLAAFPELKEVGFARPNATHNKKKPIKLPYVFQTPASGWGDNEAHEVLWYETVLQEPRAWNDVEKGLRVLVRFGAVDYETSIWIAGRYVGGHRGGHVPFDVDVTDALTAASNEGKESKLVMRVRDSPATWSSPASVWMEVVPAARVASSSEGTVLQSNDIEQGVLKAKVNVVGRRAGAKYDVEIESSIGGVSVGKTRQALLKDKDYVKLDVNMKASAEQLKQLSAELTGAAPTDNTDCWKDGVALWSVDHPTLYDLKIRLYDSTGALLDEVDTYTGMRSINWTTGDGTFRLNGKPIFQTLTLDQGYWPETGITPPSSESLKLDIELTKKMGFNGCRKHQKVEDPRFYYWADKLGFLVWGEIANAYEFSEEYMKRFDQEWTEAVRRDINHPSIIVWTPVNESWAYPSLKDNVEQRNHIRSLYYMTKSLDPTRPINDNCGWEHVNSDLSTFHDYNDAPALEKSYATLESTMGTKLAGRGMFVGPAGADAGSQHKPGAPVICSEFGGVNIKPKSEADKATDRDWGYTTASDPQDLLKRIEAIVMAVIKPGHISGVVWTQITDIEQEVNGLYSYDRKEKIDPAEVKKIMDRAAKLYLDGVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1F0</accession>
    <name>A0ABR1X1F0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672157.1">
        <property type="nucleotide sequence ID" value="XM_066808539.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041599"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF414">
        <property type="entry name" value="CONTAINING AMINE OXIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="67"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="538" mass="60430" checksum="57D06184D53CC21C" modified="2025-10-08" version="1">MDAYSISYTSPSRRNSSRIWQDLKTCRLHSIVELDSRMEENLASKLGKQRLRDLSRRPHVGIIGAGLTGLRCADMLLKYGFQVTIIEGRDRIGGRVHQEQLPSGHSIDLGPNWIHGTNDNPILNIANQTDTKVGTWDTESYLFDEAGQLLALADGEVYSTMMWEIIQGAFRHSNKNTATISPDESLWDFFQVEVTRRIPESKPDYATKRQFVFQMAEMWGSFIGSPITSQSLKFFWLEECIDGENLFCAGTYRKILQSIAKPAQEGADIRLTTTVAQINARDDADKVTLATDKGDMEFDEVVVTSPLGWLQQHPEAFVPSLPPRLTKAINSIGYGCLEKVYISFPKAFWLIPDSEGRIVKGFCQWLAPNYALESNPQKWTQEVVELASLDPATSQPTLLFYTYGDQSRFLTNKVRTLQTQEKKEEFLFDFFRPYYSRLPHYDAESSDCKPVGSFATDWLHDDLAGNGSYSNFQVGMTEGDQDIAVMREGLPERGLWLAGEHTAPFVALGTATGAYWSGESVGRRIADAYGRGKNAPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1U3</accession>
    <name>A0ABR1X1U3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672286.1">
        <property type="nucleotide sequence ID" value="XM_066808668.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041728"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="297" mass="32256" checksum="D6D133D797CDFC2D" modified="2025-10-08" version="1">MYTLSLVQIAVSGLLAASAVNSFELPGHRDLVARGAGALVAFAIPAMAAPVANIDAREPHHKGAKGGKKNNKRHHKGAKGKKNNKRDVEEEDHEDDEHAAELETREPHHKGAKGGKKNNKRDDAADDDAEAEDAHTTQAEEDAMAQSVDKREPHHKGAKGGKKNNKRDDEAEAEDAHTTQEEEDAAAQSVDKREPHHKGAKGKKNGKRDDDEAEAEDAHTTQEEEDAAAQSVDKREPHHKGAKGGKKNNKRDADDEAEAGDAHTTQEEEDAAAQSVDKREPHHKGARYRPRGGKKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1W4</accession>
    <name>A0ABR1X1W4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672294.1">
        <property type="nucleotide sequence ID" value="XM_066808676.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041736"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="441" mass="46946" checksum="A633BB91DC1C36FA" modified="2025-10-08" version="1">MGAGSQPSEKKAMKATVEDEIPVRQPAPKPRESQQAGQWPAQSAQQQPGESSSSGLQSAGPGFNHRVTNTPEGLRVNGINPSFGQQASIHQIPGRHNCIHPHYGPTLAFPFSYNKLPGLPNIGDPSFSNATFLQNHNLHHHNNNFGVSGLPFFTNTRYLSPFVRNPSSFIIANMAADYGTGSMPNTGQHFQPPVPDTTYGPIPHVYHPRSDNSHRVVTVGTAMPGFNHSATCACHVQMGAMPQVVHQVAGYPHNHFVPVAPGVSTAPFAVGAGMGYPSQPTIVQAGHAVQPIGGAGGPPFFAHGAAGPSGQPVLAQPAMMPGGMPAGGPGMAVPVSGQGPVFIGNGAPWRSWFYPPGALPDIMGVGKTVAETQAETLQSGHDQGALEPQDFKPADDDPSRMYFCRELDGNWILRNRYTLDNIPIRWYVTTNGVFYAVRLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X290</accession>
    <name>A0ABR1X290_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004478</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672411.1">
        <property type="nucleotide sequence ID" value="XM_066808793.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041853"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF142">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046778461" evidence="3">
        <location>
            <begin position="19"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="431"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="50119" checksum="7DCE71FFA7F8D9AE" modified="2025-10-08" version="1">MALKLTLMSLASLPLAQSESVLGVYIFHRHGDRTPKSHAPANLTSLGAEEVFLSGSYYRSRYVASDASSPIRDLSHDIAVQSQLSVTAPDDAVLHNSAQVFVQGLYPPVGRLSAQALANGTEVEAPLGGYQYVPVKAVASSASSTRADAENNEWLQGGSGCGNAMVSSNNYFASSEYQKTYSDSKAFYQGLLPVISGTFDADEANFKNGYTIFDLINAARIHNKTIPSSDLLTPETVAKVQDLANIHEWNLAFNESEPIRAIAGSVLAGQILQQLQSALDGKSKSTSPLGIQFGAYASFSSFFGLAQLQKLSADFTGIVDYASSMAFELVTNSTSSPVSEDDVSVRFLFSNGAAGAAGNVPVAYPLFGRSEVLLPWSAFAGEMNKFAIGDTKSWCTACGNSTGQCAQYASGSSSGGDATAASKSGNGISTAVAGVIGALVTLVVILGIEGLVYALAGLRLVKKSSLAAQATKVEVSGASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2Q3</accession>
    <name>A0ABR1X2Q3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 16</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 16</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED16</name>
        <name evidence="13" type="ORF">PG997_004655</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672588.1">
        <property type="nucleotide sequence ID" value="XM_066808970.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042030"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048338">
        <property type="entry name" value="Mediator_Med16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048339">
        <property type="entry name" value="Mediator_Med16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021665">
        <property type="entry name" value="Mediator_Med16_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13224:SF6">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13224">
        <property type="entry name" value="THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20719">
        <property type="entry name" value="Med16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11635">
        <property type="entry name" value="Med16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit Med16 N-terminal" evidence="11">
        <location>
            <begin position="246"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Mediator complex subunit 16 C-terminal" evidence="12">
        <location>
            <begin position="860"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="796"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="796"/>
            <end position="815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8089694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="974" mass="107140" checksum="C8B4BB907539A2A0" modified="2025-10-08" version="1">MPLILDNPMEGAAMQVDLGDVDDLFGDSVPLNLQARPPTKRLLLRLDELRNRGSCQGLAWSKSGTIASIAPDGQALDLRYIRAHPKDATWGLSEPTRCAVSPNISGGPIVHISWAPTQSSELAVIDAAGRVLILNFNTNLNKMYPSRKWDGDPVDDLHAVVGTYWMNPMPSHRGVGNPLHAPIVKDGQNYQIETTLVHQHGPFHPNPTRSAFFCVTTNGLLKMFWAQPNGRIDETPSRTREWKCMFVALATSSKQLQLVQMQLDWGATGNKGAPPGNLQLNPTLKAKHVIASSWLPGGSNETPLDSSMTQLSHIKLLPSAYDQGTKNVFPLIVLTVRSFVPPSDSPYSQEVQSIIDRWEVAFDQPQTLHPSFEQLGSRRNSVGAAPPMGPGMKRLDPIVINKIVTGIHMIRMGTIIAFTYHDGTTEYRDRGTLAETWNSHNNLDRISSVHEAGFTQGGEPTCLQTAISPTHFSVVQLCEDGKVKWHPIHYTLADPSAMSDAQQQAVVAALTMSTAQAATTQSNIDDILAVARYFVGREKFAEQWITEMCRLMRISVDYSEEAHHDSLVRNNLLQLCLSTLNNLGWNGEYQPRTFRGKLSMFALHLRNIVILITIASNGSIQLKNNTSPLDEPEVVDALAGCCKWSIDLLCWLANSLFNLLDDAKFLGFLESRQSFNEITAYLLSKNEVALHMVLSSAIRGLLSAVCRRMAVLQGISQRALTYYETRNASGSKDANGPPGTKSNGPPAALHLAYQKMYRYTNASLINVAEFDKLLTTLGADIRKQYSDSFAELAKRAASAAQQPNNSNNPQAPNAPKLNPGEEAVKRAQTHCELTLLLAGSLPPPFLNVANKFFKTDLKEFRTHTDPAKLFFADYGILEVDDDARALAERRQKGTRVDLFKRVEIYRTKEGSSAASAGGSGSGSEQVQWRRCVRCASVMEDVPTNKPGITFVLSQQRNCSCGARFALLGKGEVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3K3</accession>
    <name>A0ABR1X3K3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisomal membrane protein PEX17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672884.1">
        <property type="nucleotide sequence ID" value="XM_066809266.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042326"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055334">
        <property type="entry name" value="PEX8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214:SF1">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26001">
        <property type="entry name" value="Pex8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="59659" checksum="7F4412B0C4FD370E" modified="2025-10-08" version="1">MSSADRLLTTTLRAYQEPHRPADLDRLHASTATLLSNLNNHLNISLLTSHLLTARAIWGSPSPVYNTAALHVQRNEAENAKLKWGQQPVGSGVRCDAWARAVAKGADDRSERWKHLLVLTGTLMGMESEDRRALSRGLRATLEQAVVTAANLALETINRRVVPTGELGSNAAMLALAYVFPVLSDHHKQMLNCDSVLPAAVRAMIGPEGFQNGDFLRSISAGNVAGHETFYRASPSSFAQVQQLEARPLPQNMGPLSRLTAFAVYVFTYLTSLDIITRYPDACVRFLREAQPAVVPGQPNSQPLTPLDQARRDSRADPGDRAPLRRVIALASRAPDVAHPPLYEAAHAAILSVLCCPQHATLTIALIPFYIETLLASFPARISPRQFRLAFKTVVQIASPPFPIAASHPHLAETLLEMLHFRSATAMTYPLPAEPGTGPGGSGDNVMTGDQQQPLPPVSEQTTLDWLTRTAEAMNAVVDPALREVVRKRFWDVLVSGEMDVERAAIGVAWWGIGGGREMVLLNQPALPKGDGEAMMSGALGGNRLEASRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3X8</accession>
    <name>A0ABR1X3X8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADH-ubiquinone oxidoreductase 24 kDa subunit-mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005081</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673014.1">
        <property type="nucleotide sequence ID" value="XM_066809396.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042456"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371:SF3">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01257">
        <property type="entry name" value="2Fe-2S_thioredx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="256"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8090120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="298" mass="32156" checksum="CBFCDEF23FF718E7" modified="2025-10-08" version="1">MASKLCPMLLRTAIRAAPRAPRTQFRAFTAAAVRRSDALSVTLEANDGLGIREAKSPVSPVLNTGDISMPKSYEGYHGKLIVSFSTNQTAPQHPDNNPELPFKFTAQNEAILTEILKRYPPQYKKAAVMPLLDLGQRQHGFCSISVMNEVARVASFYTMYNRTPVGKYHVQVCTTTPCQLGGCGSDIIVKTIKEELGVSHGGETTPDGLFTFVEVECLGACVNAPMVQINDDYYEDLTPETTKQLLQALKASASGGGNTTLKVPAPGPLSGRQTCENSAGPTNLTSEPWGTETTRSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4I4</accession>
    <name>A0ABR1X4I4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6536 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005270</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673203.1">
        <property type="nucleotide sequence ID" value="XM_066809585.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042645"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046623">
        <property type="entry name" value="DUF6536"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35395">
        <property type="entry name" value="DUF6536 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35395:SF1">
        <property type="entry name" value="DUF6536 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20163">
        <property type="entry name" value="DUF6536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="513"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="564"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="635"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="669"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6536" evidence="3">
        <location>
            <begin position="159"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8090309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="780" mass="84505" checksum="0376822676E04BAE" modified="2025-10-08" version="1">MEPHFRGVRLDSSGPGAQKQPRKMPSKQSMQWPFHRRMASDSPSSVLTSHFRRPSSGWNNLKSFFKVEEDTVSLSSKPLVPDYVVHYIRGETPETLAKKREQRRWGERMATVTPQRERFMSQQVELEDPWASRTKLNIDGNGYANEDRQRGVGRYFTGWKGGATCNIILAFILLVIAVVCLILAITRQVVSGETIIFSGSCDTASSINTGLHAAINVFAITILVGSNYAFQILSSPTRLELASAHNKKQWLDIGIPSLRNLFHVSGLRTALIAVALLCAVSTQIIYNAVIFTSPTGFKSDIVVVTNDFLTGAPFSNGTNFNRGDMSQSDILSLQNAASAGNLETLATVPCLQQVGGTFDTTYDALVLVTKLNSARSSVIQTGKSGEMFQLNSMSSVAISVPVDEKVVDRCLARQGLPQTCKVSVSSPMLGIVGLLHLITLFTMAAVLSWRNFEPLVSLGDAIRSFMRNPDPTTTSACFLDKQDVNEGRWGFNEAKYLTSTDHFWFFTPSIKRWVLTIVSWILITAPTAAAVALIIEHEPTGTLTPLATATPYTTFLLGDANAPLLTHAQAAVLAAAPQLLIAILYLTTNSLLTTFWLSHEMSFFSIEPQPLRVSADPVGYQTTSLYLTLPRPISWALYVLFIAMSFVLSQAVFPAIVSTGTARANNPEIVGIGFSTLALLILLALLVVLILGVLALGLRRAPAATYANGEQKGNPLALRGGSCSAVLSAKCHPAPGEPERSWRCPLVYGVVVDAVGAQQVGHCAFSGVSVGSIDTGKIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4X9</accession>
    <name>A0ABR1X4X9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673364.1">
        <property type="nucleotide sequence ID" value="XM_066809746.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042806"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="75" mass="8274" checksum="65DE227F22AA85BD" modified="2025-10-08" version="1">MTTIVPGADGICVAAQMFLDRVAERIGDFSDTLGIDVFPVKQSEGDFLQYTVYICRNYNGPTNWLRFGDGPPTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7P6</accession>
    <name>A0ABR1X7P6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001867</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673478.1">
        <property type="nucleotide sequence ID" value="XM_066806182.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039242"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056026">
        <property type="entry name" value="DUF7607"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF17">
        <property type="entry name" value="HELICASE-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24580">
        <property type="entry name" value="DUF7607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="978"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="100"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="316"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="354"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8091506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1139" mass="129063" checksum="FA9BD378C1C04D8A" modified="2025-10-08" version="1">MNDPALWGPDHVVAAFREVWPEMPDDVENAICRHEITGLSLLPLATRPKRNQDFPLTPGTKRRRIQPTTVSSQLADPLLPQSTPSGLWFKKDGLQAIDILGPDSDPAADGGDRRINIRTYGPSYRGHQRQASRLLTRSFLSTAGEPRRSKLKPDQLAPPNHPLHDPVLPPPGESDDEYDSETWAELQEDMVNDGAQSQHDGVRQYLTTDQARDELSQAVERFGNDWARRKARQLAYDAPRIWEELHTRTSAETTRNLKQRLAELNQRIDRLRHQLLSPPNEWRTAVELVEAAAAIKPSAEDRAFLLWKMRLAVQVSPPERPSLSRRRKPKASRPAQRNVDSEDLDSDSGFSFEDVQEDIDSEEDLNSESDKASAGPSSKKGSALCVIDLTENSEPEHHDGETGESPPPLAGSGSGSASCVIDLTGDDAVQPGEEQQHEREEIEDEDVHTMHAAIDQVDQSSWGRCCRLFRHEIGNTGIAEGHRYHFRGTRLSLHPYQLYAVYWILTQPLRQVAGAVLADEMGLGKSFVAIGLIVTRSRLLDAMEDFKTHPKQRGETRQLALDYVSVGPQAIFTPKSIVQDWVDKLEQTLGDLTGEGEFRLHVTLPQSKSSAKLETYRLTKTESSILQADMEGHQPENQKQRAVQGQRKWTAPDLRISPCKGQARQIVVVNSSYPAGLFNFFEFEIRRPRSQEFIASVFQICLGFVVADEVHEYKGQKSAPPKLIEVIRSIWKHGHAPFWLGMSGTPNERGPMDLAAQVHYLEDVALKTWPGMNQYQATVRQLEGLHKLHKAAYVLMAPGADTEARQEYLAKRKHYHNQQAPIYSTFLMRRRLDSTFLDKPVCKLQRVVPITKDCPVDPSFLTLFRPLEAEFEQYVEETLGARIRVWRDQGSRPQDKPTREGVLRSSLTRLRDQRIYAVFPSLLRLYDEGRLPDLPPVRPEAVDEHMLVVRSSNPEAAKRSPFYKHILDIAGNSTKIKELDAILDHVLEDRREHPQKARAVPKNILIFAEVPANTFLVYLYLLRRRSHQFDLNLVHRQVTHADRLEMIDAFRAWDNERPVIHICTPRLGGSGIDMTRGSYVIFVDLTLMQRDEDQAIGRVNRPAQTMPIEAYVLKATGARVEEVIGDRKRTRKTLSCSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X896</accession>
    <name>A0ABR1X896_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Inositolphosphotransferase Aur1/Ipt1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002057</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673668.1">
        <property type="nucleotide sequence ID" value="XM_066806372.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039432"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03386">
        <property type="entry name" value="PAP2_Aur1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052185">
        <property type="entry name" value="IPC_Synthase-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310:SF10">
        <property type="entry name" value="INOSITOLPHOSPHOTRANSFERASE AUR1_IPT1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="395"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Inositolphosphotransferase Aur1/Ipt1" evidence="6">
        <location>
            <begin position="197"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Inositolphosphotransferase Aur1/Ipt1" evidence="6">
        <location>
            <begin position="373"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8091696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="445" mass="50638" checksum="42664BAAC1C436E3" modified="2025-10-08" version="1">MEPNTGVPSLPKLKVWKMPEWVEPVIIVGILFGAMFVTRRKSYSILDSSNSPSYKPIKPVRDDFDYGRDSFDSDGYLPPSPSPSSSQRILGIWTVHTPNSFRFARHVHSRILQKFPFLIEMFYWILTYFFYRMTAYLSAVWYGGSVGLWNVAQDHGISILELEVWITGSSGTGTDRWIEWRVQQWFLAGVAEGDIRELFLTILNRVYALIHIPGTVGFIAWYYTMAPSHQRFCTVRRTMSLLNLFAFFTFTVFPCMPPRLLPREYGFLDTVNAEDAASVWMSGNYVNKLAAMPSMHFGYAFCIGCVFVYESGFMRTWCRPFGAPKKLTLDNASILSPTPTSNGDDLEVPRFLKQMEDAGEQETRRSAFVRAAYLISGVCYPALILLAIVSTANHYILDAVAGAFVVLISYLGNRFLLSFLVLEDWLLWALRLEKPEPTTGMKNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8F4</accession>
    <name>A0ABR1X8F4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673707.1">
        <property type="nucleotide sequence ID" value="XM_066806411.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039471"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="3"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="331" mass="38021" checksum="1937771E2AE1F14F" modified="2025-10-08" version="1">MEFVKFPEFPPEIRDQIWKEAVCEEAEDRLVFVHKDTLRVFPTKNNTSPLLSVNVEARQVALKHYNVRLPIFHLPPVKYEPPLSFVDWIVKTADIHWGRGLSSGGGCCSNRERYWHYYAMSEFADEAKHLIEDTSEDEELPSGFIFLNESTDRFMLSPDISFPHKVENVLAWDGDEAAYEHVQENPTPDLVAYQPILDHQTNFLSSKSYERCEIQRQHMSPRLPLEVRLNIRNVVFCDVTDDPPKGDSSDDSRAAYSTVLARAWARNPTETDVVRLWQSMDFPPVEDALNHSEPKMMYLEVNASDSAALIDEVEENTARSLVIYELDDGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8N7</accession>
    <name>A0ABR1X8N7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UbiA prenyltransferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002197</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673808.1">
        <property type="nucleotide sequence ID" value="XM_066806512.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039572"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8091836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="295" mass="32707" checksum="E755FDF72C5C3F92" modified="2025-10-08" version="1">MSTSGPVDAGMLSVLGEKAAENSTSQAPPPGSNSHRRPNLFTTIINVILHELDVTERLLRSNAGGSCFVFLGGLLARFLRAPPPSLADAVEATLNTLAEDALNKPYRPIPAGLITVDQAKARWFLSWTFGPLATYHLYGPWAAVHLLEFEAVITFCYVWPRWFSWFNRNLFVFLLYTIQDRILNQALLEAAVPGWDLSVLIDLTVSAWFMGTVHVQEFHDLEGDRKSDRKTLPHAVVASRTAAAAGRHVGIHCGVRRRAGVLRVPESYYEARRLQPRLDRAVVCVATYILCCPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X975</accession>
    <name>A0ABR1X975_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane ATPase</fullName>
            <ecNumber evidence="10">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_002341</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="10"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673952.1">
        <property type="nucleotide sequence ID" value="XM_066806656.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039716"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02076">
        <property type="entry name" value="P-type_ATPase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="409"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="771"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="798"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="834"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="864"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="900"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="940"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="110"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8091980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1023" mass="112271" checksum="4BA437F78C4A0315" modified="2025-10-08" version="1">MAPNLKKLKGLGGHKSNPEYTAAAMEEGADLESGSFLTESQRNNDVEPQPVKQNPQGDNPYMDEYKALVRFVDTYRDPNAENEEEEDFSGEGKKAPWWAFWKSGKSGANTASKSDFVTPTEWVKTDLHKGLDNLEVERRRKQSGWNELAAEKENMLLKFIGFFRGPVLYVMEVAFILALGLQDWLDAGIIIGILLLNAIVGWYQEKQAADVVASLKGDIAMKALVVRNGKEEEIRARELVPGDIVIIEEGNVVPADARLICDYENPNGQAQYQAELSAQSGGTEKKGDPEDDEGTPHIGHAIVAIDQSAITGESLAVEKYMTDTVYYTTGCKRGKAYGVVTSGAQASFVGRTASLVQGAKDSGHFKAIMNSIGASLLVLVVFWILVAWIGGFYRNLNIALPSDSSINLLHYALILLIIGVPVGLPVVTTTTLAVGAAYLAEEKAIVQKLTAIESLAGVDILCSDKTGTLTANQLSVREPFVMEGVDINWMMAVAALASSHNIKALDPIDKITILTLKRYPKAKEMISEGWKTEKFTPFDPVSKRITAVCTHQGVRYTCAKGAPKAVLALTNCTEEQATLFREKATELARRGFRSLAVAVQEEDGPWEMLGMISLFDPPRSDTAQTIAEAQALGISVKMLTGDAIAIAKETCHMLNLGSKVYNSDKLIHSGMPGTSVHDLCERADGFAEVFPEHKYQVVEMLQQRGHLTAMTGDGVNDAPSLKKSDCGIAVEGSTEAAQAAADIVFLAPGLSTIVSAIKISRQIFQRMKAYIQYRIALCLHLEIYLVTSMVIINETIRADLIVFIALFADLATIAVAYDNAHFEKRPVEWQLPKIWIISIVLGVLLAIGTWILRGTLWLPSGGLIQNYGGIQEMLFLQVALTENWLIFVTRGFETYPSWQLVAAIFGVDILASLFAGFGWFSGTGEETAWSMNPKLSQNGAVDIVTIVVIWLYSIAVVIVIGILYYAMTNWSTLDNLGRKKRSKQDTMMENILTHLSKVAIEHEKDERGERYYVAQKTIIEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9H6</accession>
    <name>A0ABR1X9H6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_002420</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674031.1">
        <property type="nucleotide sequence ID" value="XM_066806735.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039795"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF17">
        <property type="entry name" value="NADH DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="6">
        <location>
            <begin position="19"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="7">
        <location>
            <begin position="429"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8092059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="55498" checksum="73F8A020F838A2CA" modified="2025-10-08" version="1">MLGYTRAPSKHSDRGAKDKVVVLGSGWAGYGFTRTLDPNKFERVMISPRSYFVFTPLLASTAVGTLEFRATLESVRRLGLDHFHQGWADDIDFNRKVIRVEANVSDDMRSRMNQMVAKHKSPELPIKQGPIFEVPYDKLVIACGSYSQTFGIEGVREHAYFLRDVGDARRIRLKVLQLFEKAALPTTFDEERKKLLHFAIVGGGPTGIEFAAELHDLIRDDLAKLYPTLQKFVAITVYDVAPKVLPMFDQTLANYAMNHFKREGIQVKTQHHMTRIRPDEETEGCMKLNIKEYGDEEVHAGIVVWSTGLMQNPLIEKLTSKALDCPPAVGNEELSNQQIRLQKNPKTGSILTDHYLRVNVVPKDAPPENGNTYPNPGAMSDVFAIGDCAAFTDQALPATAQVANQKAAYLAKGFNKGTVDETEFKFRNLGTMAYLGNWKAIHQSSADEMKGWTAWVLWRTAYLTKSMSVRNKIMVPIYWCITWLFGRHTSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAZ0</accession>
    <name>A0ABR1XAZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674583.1">
        <property type="nucleotide sequence ID" value="XM_066804810.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037870"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="458" mass="46749" checksum="F1BC9B8CFBD3F2FB" modified="2025-10-08" version="1">MSASNATSTDTQGVDLTTQSDPVTTDATSKPSPSTDTPTSAAPTQASSPDTSPAAAPTTPTKEPAPSPSSDPSPTTQQQPTTPTQQPTTKQPDPTTPTAAPTTAPTTAPTTAPTTAPTTAPTTAPTTEPSKTDQPSPTKPSTLQTSPTQQTTKKPPPEPSTTLIPTTIITSENGSTVVKTITSTAVSTPTVSPDDPSGTSPNGGNILQSNEASSGGLNQQGKIAVAVVVPIAAVALLVVAGIFLWRKRKQRKDAEEERRKEVEDYIYNPNADPTMPDVGGAGGAYEMKEDASSGYRGWGSTTLGGSTGRKASTTMSGGAAGAPYSEINGPTWGNASDTRSGEPLMSDGSRSPEGEILGAMGPSTAETRGNGNVHRGPSNASSSYSATGRSEGSAENNVGVAYGGTNAYYDQYGNPYNESQPGAGGAQPVIRDNPARRNTRIENPSHYPQQSAGISQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB34</accession>
    <name>A0ABR1XB34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bms1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000541</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674629.1">
        <property type="nucleotide sequence ID" value="XM_066804856.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037916"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF1">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22298">
        <property type="entry name" value="Tsr1_G-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="6">
        <location>
            <begin position="88"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="821" mass="92371" checksum="99ECE7A8C87C5041" modified="2025-10-08" version="1">MSASVAHSHRPTTRVSHKGFKSKKATKGALREQAKGTEQAFQRARSAQDATPASHVEARPTKPREATPTTKEQGTPRPDIHIQGSRWRPRIVAVVPLCGDADAAAAIKSLNASLDIETEVSEASFRVPVDRFKQKLQYIPLKRDLTACMDAARVADFVIFVLSSEVEVDPLGELIIRSVENQGMSSCFTVVQNLDKIQPAKARPDVVKSLVSFITHFHPDQDKVYSLDSRQECSNLMRSLCNSSPKGVHWRDQRSWMLADEIQWPSSPSESTIFTGVVRGKGLKANRLIQVGDWGTFQIEKITAAPSEKKQKDGDVTVEGAEEVLEEPTVLEHDKPDDLDELAPEEARMDDADDAMSVATTSKKGVLLDDHHYFSEDELEKPTKPLKLPKGTSNYQAAWYLDDVSDSESEMDDDEMQDVDADADAMQAAPEDGVEGLAPAEPTEAGMSEYAKSEKFEELDDADDAAQLAAYRESKKSEVEDDMEFPDEIELHPHVLARERLQRFRGLKSLRTSPWNTEEDRPYEPEDWSRLLPVTNYASSRNHYLKRALVGGVKPGTRVHVHLKAVPMELEKTYKPTQPISLFSLLEHENKRTVLNFDITHKEDYEKSIKAKEELIMQCGPRRFVINPLFSVGGNTENDVHKYCRFLHPGQSAVATFMGPITWGAVPALFFKRTIPGEAKDEDDDDEESNLPLQLVATGTVRAPSTNRVIAKRAILTGHPYHINKKIVTIRYMFFNREDVEWFKAMPLWTRRGRSGYIREPLGTHGYFKATFDGKINPQDSVGISLYKRVFPRTAKTFSGPLLEEEEFEGFQDEVMDEDIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBP2</accession>
    <name>A0ABR1XBP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000816</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674904.1">
        <property type="nucleotide sequence ID" value="XM_066805131.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038191"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="391"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="595"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="957"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="995"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1181"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1236"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="409"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="444"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="459"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="481"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="608"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="704"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="758"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="813"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="888"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1046"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1086"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1138"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1185"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1270"/>
            <end position="1283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1283" mass="139826" checksum="5E36390445B06ACF" modified="2025-10-08" version="1">MDGRAPVRATCAKPDCPNNQRITVECQWCQLVRYCSDDCWEQDQARHGSLCSSHQSRKGKSYKVGQDTRELVVEDDGELPYPHLKSGTLQEAPRHGEEPRLFSSNKVKSLITPEVSEAADEININIEGFGDLGLVIESFLSIPKGTKKEISFHMVEADDEAIARLFVILTMASRCNHYLQTAEAILHYWYSAFLPIGCDEAFVQAKLNHGNESPTNLFVYWFSNKFARDDLVSFTQACHLPKRRAMLQRAHNISRRRKGISAELLGQAHPEWRSSQMEYLKTGVLGPIGASKEDFRHPNPSFFRNWERCRDYGFDPMEAWVGIYEPDSRSDLPEDDGHGNFFYYMRKKLMNFLKVLDHTEDYKIIIGPQSCPAPDIDWTAKWQAEPKLAMVATPKLKSHPTTAPAKVAEGTKEQGDNPEKPQSGEQSRRKRMTKSERRKAALANKRKLAAAKSAKKPKVHESLKSKYEPTVDTSDPESDTASESSRVVFTPSTSSGGSEPVAREYSHQQLPMTSSPEDDDEDEKDGRETDQESAVSSSPTAVEEQPASSPADILQEQPAASLAEETEDQSFGRMPVFTPATDSRYITPCLSSFGSLPSEATVSLPPNIATSPLSDQQSETMRRQGENPWEVYAEDLVSTSEGKGPGHTAAESDVSADSQPHPMQLPPLYTPAQLSGPMIGLWPEAPEQQAPEEPIHEAPGNGDGTNAQLPSYSQFMATTQAPPASQSRDPAAELHLAPMAHRHHAMPDVVARPGPVESQASYNQTAPYPSASQAPLYAPQDPEIEPVTYHPEPVGQPDPQTEDKQPESAMYNPDDRNPVVSDSHTENHTVKGGSDDVKVQETAGKDDGCVDEEAQDTGLQIEADNGGDAIVDENTGAEAQDTEPKLTKAQKKRQNRKARSKAEKDTAEAEAQVLAQAQSEARVLARAEAEARAEAEVEAVLGAIERANGLTAGAQVVAQGEEDSETPAAKPLTADQGDGEIGGLTGLDILAAAAAAQETQKSRRAFRAIQTISHDSPANAPGPAPLENLTQSEPDADTDAQAYDVPNNTPEICPSNESPTNAPVPSSFENLDQSESDVGVDVQAYVNPSNTSETGPPNHSPVSAPVPSSFEYLDQFETDANVQGHDDTGNNTLETGPSDDSSVDAPVPSSFEYMDQHVSDADVQSHENSASTPTAVLHASIPRSAPAPCPDPPSGPTILENGTRIREGYTEEAKDPTKRRPVPWTAEDWAAFGVTPSLRGPTFIKPSERGSFFPEMFPEDYTDRCSPKDEEIDDDKADLGEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBU9</accession>
    <name>A0ABR1XBU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674894.1">
        <property type="nucleotide sequence ID" value="XM_066805121.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038181"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="89" mass="10295" checksum="DE5A8FF6F5BD82C2" modified="2025-10-08" version="1">MAFSQQDNRFIDFIRMLHARGPNLTASQILERCRTNFGRHPSMKVQNWLYKSLVDFRMARENNECHPGVLPIVERGISPSSGSTYPDQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBW8</accession>
    <name>A0ABR1XBW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dimethylaniline monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000763</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674851.1">
        <property type="nucleotide sequence ID" value="XM_066805078.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038138"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="598"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="633" mass="71188" checksum="C0D382C5116816F2" modified="2025-10-08" version="1">MLRVAVIGGGPAGLATLKFLKTAHQYFGGEPVDVVLFESADVIGGTFVNKVYEDAEMVSSKYLTAFSDYRLGPDDPDFVTPAQYVAYLHRYCEEFDLVPHIHLGAKVVRVSRPPPSHQNGYTLTVEYRNGGHKDHHFDAVAICNGLHNQPAGHRIPGLDKVLHSSVLHSSEVKGRQDFFKQGPILAPESGPHVAILGAGETAMDIAHLAVTTPGVETVMLCHKNGFWVAPKKIPEPTVLRIWHGSKNPKPIDTAVASLFDTAYCHPKLQRGSMLWLYYTWAVSWLMYTATGTKFGMDQWVGEYDEDRFHTDGIFLVKSVRAMPYISWPWRKNSIGHRIRAFVCQMPIQDVRGRRIQLAPWPTHVRDDGTWAFPDRGRPEDEEVKAMEDYKPTVVVCCTGYDRSFPFLDHDFQPTLDQANVRGVYCSDDVTVGYIGFVRPNLGAIPPLAELQAQLWVLRLMQWAHRRDQEHHGHGYGGGTKQSGYNCEQGLQHYNALFSHDPNAVEAYEISYRLRPRGEHDLAHDKGGVDHESYAYQLALDLGAAPTFSFMVHQGPRALWTWAMGSNFNTKFRLVGPYANRRLALEIMRSELFQVTSRLGGFVFFVLYSLVPFVGFGAMSLGLYAWDFIKGLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCE2</accession>
    <name>A0ABR1XCE2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc/iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001056</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675144.1">
        <property type="nucleotide sequence ID" value="XM_066805371.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038431"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF44">
        <property type="entry name" value="PROTEIN ZNTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045870919" evidence="7">
        <location>
            <begin position="28"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="490"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="109"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="366"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="513" mass="53683" checksum="435F606976CD9855" modified="2025-10-08" version="1">MVSSMRNSGGWTRALLASLLLLGEASAHHMAPNARRQQQATTTPPPAPTTTASPKVTAISDCHNHGATVFCMFGTSEYQILGQATATTPPPPAYTDCHNHGSDMFCVGPDGSDVEVAPEGSAHESEGKPEGDHGHGHGHGEGDASSQGGVNCHFHAGVEHCVGAGQSEASAATASCGRRDRDYNVSIRIGLLFAILVTSFLGAALPIVLTPVLPEKLGIINVFFKQFGTGIIISTAFIHLFTHAFLMFNNECLKDQIKFEGTTAAMVMAGLVISFFVDYGCHRLANKRKELNQTAASATSNNGLINVLILEAGIIFHSILVGLTLVVAGDSFFITLFVVILFHQMFEGFALGVRIAAVQQHEPSSATNASHLPSVEPPSAEAKTIAGGSDDGGSHGSSSAPITSSSSRRVSLWMWKKLSMAAVFGITTPIGMAIGIAVLQSFNGQDPHTLKVIGSLDALSAGILLWVGIVGMWAHDWMMEGGELFNAGALRTACGLVGLVTGMAAMGVLGIWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCH9</accession>
    <name>A0ABR1XCH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675165.1">
        <property type="nucleotide sequence ID" value="XM_066805392.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038452"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="14861" checksum="056E3B8496CC69A1" modified="2025-10-08" version="1">MASGGIKRSQSVRTGNGPLRKSSWGGGLGKKYGDLEGDKENEVIDSVREIDEPSDEAEPEAEPEAEPEAAPEPEPESAVDDAASEETAEPNEDPEASGAERTTPVMLTEGGYTEDGYTDEDYDSRTERGRDGEYRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCW1</accession>
    <name>A0ABR1XCW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apc15p protein-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675244.1">
        <property type="nucleotide sequence ID" value="XM_066805471.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038531"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008402">
        <property type="entry name" value="APC_su15/mnd2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05841">
        <property type="entry name" value="Apc15p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="103"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="216"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="40841" checksum="F77EA8F89C5CE23D" modified="2025-10-08" version="1">MLSLLPDLAPGDQPNICRAPLLTTNAVSFSLVQFIEKSQCCIIIRSFPPGEHAIEPHNQNQRRNVQVIERSPLARLRADEQLLDRRLHNISNFGSTWLKPPGIAKTLHQMREERREQEEHQEALRREQLAQELAEAEAAGAGPIDGVLDDQAQDGMDDVQLDGARDLDEDIPEAEDNDFGLSGEDEDEDDDEDEDDEDDDEDDPDDTIEHPEQRAARAQQALMAQRMQQAPDPFRGHAANTSQGNSFYGGEDEVDDEDQAHMIEEEDLDGEGGDMDMEANLDDDIPDAESAMGYEHTDTDASVTSSDNDEPAAEVSFVAARAPQRLRFRGSLARSDATRNSIAISDLLSMDGSSMLLESSPQLARHMGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDA7</accession>
    <name>A0ABR1XDA7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675394.1">
        <property type="nucleotide sequence ID" value="XM_066805621.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038681"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="444" mass="48347" checksum="5E00346538778E18" modified="2025-10-08" version="1">MGMGMAQPPHSGKRIRSNTSEFISATPQTTAPALRHSPSINNASVSNLSLYNPTVYNNASYAALAVASGRQTPTAGVPDYTAYSTLDAASNGYPGEPFTGAPSPVYQQSYDPRALSAYNVAYGQAHAHNGGLRSPYGQPRSNSMQNGSYAQMKVSHSGSGVPGAYSPPQEQHPSTPILQHTLPHHFGGESYSSQPAAHAAMFQGHAVSYPEPTVNPQYSPPPSQTPEHGTRQLPQTPLQEDIGIEDAQGELEQEISEHCSCGTACGNPFQDLTAFFGPAARFPKPCDANACFATWLSNQPNVEELDVDLMVDMLLYDDKSWANIKANTKAFKDWEDRWIKAKNSKAKKLKEDREKLEYELLRGALGNCNANDFHGYNYSFCRGQWVPMDAWEHCRECRMCSPAASGTASSTVVAPRIAPVRDAWAMSCRIPAWPTIPSRPEEMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDC0</accession>
    <name>A0ABR1XDC0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675423.1">
        <property type="nucleotide sequence ID" value="XM_066805650.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038710"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045083199" evidence="1">
        <location>
            <begin position="17"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="100" mass="11165" checksum="08593BD0B3284A9F" modified="2025-10-08" version="1">MVVLKNLLFLISPADSEDLEASNLLLRAPMPIVPYFKTESEVPSLCFARDQGIPDPEVIWYDSSGEHALGLNWMVLGPNHQLLRLHNASDQAVWPGKALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDD4</accession>
    <name>A0ABR1XDD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675449.1">
        <property type="nucleotide sequence ID" value="XM_066805676.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038736"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932017" evidence="2">
        <location>
            <begin position="23"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="166" mass="15314" checksum="EE28087ED494BEF8" modified="2025-10-08" version="1">MHYSALVQVLATGLVTSTAVTGFQLGAFPNRRTAGALVALSGPAAAVPFVNVGRQATPAAPAGKGAGKSTAAGAGKNAAAAGAVGAASVPAAKAATPVKAKAAASGSAAAPPPPAASGAPRHLPPAASGAAPPPPPPAGSGAPPPPPPKGSGKSILKLRGTIEILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDT3</accession>
    <name>A0ABR1XDT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metalloendopeptidase</fullName>
            <ecNumber evidence="1">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675565.1">
        <property type="nucleotide sequence ID" value="XM_066805792.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038852"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase metallopeptidase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="33765" checksum="576D295E1A4DD7FF" modified="2025-10-08" version="1">MARDNKSTDKAFPWKQDQRWPSSQRHLAVRFLNGTTEQKQLVKTVVKEDYNTIPMHIRFTFLRSHSTSGSDIRVKFTNSGRSWSLTGTTNREEEPHVATMALNLNGEKEEGKVGTILHEFGHALGLRHEHQHPDSGLVFNRRFLRQEWTDEYIQSQWLPYGIDKRRTEPYDRYSVMHYQIDKEETKNLRKSIKRNNCLSAGDKARLMAMYLEKEAKPKVPAPPQTTRATTIKKTRPPLGERSIPKKSIPTATVKYGGREYEYATEYTDRKGRKKKVTPFQQKLMQWILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEA9</accession>
    <name>A0ABR1XEA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675697.1">
        <property type="nucleotide sequence ID" value="XM_066805924.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038984"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="188" mass="21096" checksum="7E1277646C7F7143" modified="2025-10-08" version="1">MGSKPVSLKSSLQKAFRLCEEWDGVLLLDVLLATLEYYSGIIFMTTNILEGLDPAIVSRLDIHLEYSCLDFPTRLRLWRNLLPPPSIPPQPSPAETDDSDVTMTPADAAPVPDHHSLTEADLLDLAYWNVNGRDIKHAVKNARKWCYIKGKPVTLDALQTGLITTAPRSKREENVESDFNGGKRRRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEC3</accession>
    <name>A0ABR1XEC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675712.1">
        <property type="nucleotide sequence ID" value="XM_066805939.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038999"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="154" mass="16561" checksum="968414B62B568628" modified="2025-10-08" version="1">MSLALNTIQSTLSLLAHALDRIDDIMGYTFQDAVNDPSEGKIIILSLVTIPLCVVATTLRLFAPKRPGTHGFRWDDLFAVLALVGFLGYAISPLLVCSCVFFFYGNRAAAEVAFNSGIAVSGDMSDDDLAILSAKVRFSAQKTSTKILSPSLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEC4</accession>
    <name>A0ABR1XEC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_001718</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675806.1">
        <property type="nucleotide sequence ID" value="XM_066806033.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039093"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15840">
        <property type="entry name" value="SNARE_Qa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF38">
        <property type="entry name" value="LD27581P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14523">
        <property type="entry name" value="Syntaxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="5">
        <location>
            <begin position="194"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8095033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="288" mass="31858" checksum="18AB1DF1BB23DDF9" modified="2025-10-08" version="1">MSFDQLSNMESGGGSRRSGNNSRNGGGSGGAYSDSPEFSRLNQTLTNALFHLQGNNDKLRTEIDRLGTRQDKPRLRERVQALLEESRDQFKEVGEGVKKLQTWDDPAGITPTQKYQQQKLARDFGVSLREFQGLQRTALEKLNASVTAAKAAAHDEAAQSPSGGDYFHGGEQLQQLQQQEQAHLAAQDEVDFQDALIQEREDEIRQIEEGVTDLNTLFKQVAQIVGEQGEQLETIETNAINVRDDTRGADVELRSAARYQKNARSKACCLLLILAVILTIVLLAVFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEI9</accession>
    <name>A0ABR1XEI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675812.1">
        <property type="nucleotide sequence ID" value="XM_066806039.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039099"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8095039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="76" mass="8209" checksum="95A4092EFC3CDBF2" modified="2025-10-08" version="1">MTPPKTHNVITASIESPSKTETSRDNTQSYMATKNGGGDPVTALALRSESASQSTAERQARVKREVTASLKQYRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ25</accession>
    <name>A0ABR1UQ25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_015234</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660433.1">
        <property type="nucleotide sequence ID" value="XM_066819548.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052608"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="10"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8061013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="442" mass="49327" checksum="69EFFAA6A3E77712" modified="2025-10-08" version="1">MAEQKTEDFRVILVGGGPVALTAAHALSKAGIDYVILERRDQLDVDSGASVAVWPHNVRLLDQLGMLDEADRTYMPVLYKRNLRRDGSMISKSNMFEAMQINHGHPWMCFHRAKLMNMLTNNLPDPSKVLLNKEVVSIETTSTGVTVSCADKSTYTASMVIGADGVRSTVRRMMNEEASKQPDEPFVSTYKGLYGYSTKSPELDAATCYETHSGRMTIQLIVAEQQQHFLVYERLEKPTADRGPRFSDEDKDALAAKYADVKFPGREPGQWVTFADVWANRQWSMLSNIEEGVVKQWHQGRCVLVGDAAHKMTPNTGFGMNSGLQGVAHLVNRLHSLLQTNPNPDGAALTKVFTEYQAALIKNSKTTVDMAGLYTRLVAWDNPVWKFLDQYFLPYVNGDVTSLNMLMSPIVQKGVPLDFLQENAYKTGKYSYHTGQATIKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1USY2</accession>
    <name>A0ABR1USY2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peroxisomal membrane protein PMP22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_015351</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660550.1">
        <property type="nucleotide sequence ID" value="XM_066819665.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052725"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF93">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN 25D9-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="35"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="251"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8061130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="34824" checksum="4B882A498F95A64C" modified="2025-10-08" version="1">MTIKIERDTVRDTVIKGTDSVFDAAHAAREAAHQAREAAREVVKGPRDGPLPGTTGKHPISESIGTAITGGKAMAGTKGYMMAYINQLEKNPLRTKMLTAGTLASMQELIASFLAKDRNKHGNYFTSRVPKMAAYGALTFKGRTSLRAKILQIIVSNLVIAPIQNSIYLVAMALIAGARTYHQVRATVRVGFMKVMKVTWVTSPLCLAFAQQFLPEATWVPFFNVVAFIIGTYINTMTKKKRLAALRKKHFGDDRGDRGDRRGEGRGSTMGGRPEDYPGHQGPMGPNPLTKNKLRQTANDVNAPWTKISSFGDIGMSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT22</accession>
    <name>A0ABR1UT22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660683.1">
        <property type="nucleotide sequence ID" value="XM_066818495.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051555"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="398"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="44037" checksum="C8BDCA776B68FA91" modified="2025-10-08" version="1">MSTETNTIPQPPKEAEALPLPESPEATDNTPVVTKDTVIVFHDAADVTLNVKGSFGAVEYKVSGMNLATASDVLRAIIFGKDGKNSVTDGIVDLDIGEVELSALETLLRIAHFDFAKVPAEVNLEGLCAVTNLTSKFQSTGLIMPWASHWLRPFAQLHKDDSSAAVNHKAAFIAWELGDAKLLRNMVKSLTMTAKVDDDGDLVNAAGTKLEDLVLPAGILDEITAIRTETIEKILAAIEAALETVSAHTGDVKFCKTGVDADKCETMMFGSAVSQLLSAGLFPVPKAAQYKESIASLVSRIEGVVLQHWEGKNYAPHASHSGCNLKFKENTKAAVKGMADPLKEAHIEHLKKQSAASGVNSHIDDHADDDAEEDAPARRTRVTDTISGTGELLERSRSTSPKSAASSNKNSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT69</accession>
    <name>A0ABR1UT69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660731.1">
        <property type="nucleotide sequence ID" value="XM_066818543.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051603"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="192" mass="21069" checksum="4554C366E10EC364" modified="2025-10-08" version="1">MPAPAPRCGLDLDFSEVVGSNCHEPICWLPFISSRFVLEMILIGFGAQDRLDRLGQFGRNKVGPSLLRSVSQVRNLSKDCPCACDNPFRSITPQHPTEQGLASLLGNPVVEKVRFSQCDLIRDAIHDHGGSLSTAFRWWDRRDAIGFLLANASSCSLAVSIRHATSAYSTFHYPRSRSSDTGRGARGVPPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTM5</accession>
    <name>A0ABR1UTM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Monooxygenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014344</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660846.1">
        <property type="nucleotide sequence ID" value="XM_066818658.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051718"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="11"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="615" mass="69269" checksum="9012F87ABD47740B" modified="2025-10-08" version="1">MKAAVGSLLSTLSNGSPSNTQHPRAQPRPITLKDVPIENQRPMKVRVIGAGYSGIYLGIRIPQRLRNIDLKIYDKNEGVGGTWFVNRYPGCACDVPSHSYQYSFDPNPDWSNLYAPQREICAYLQRMATKYGVMRFVKLSHEVESCRWDEGTKKWHLKVREVATDNVIDDEADVVIAAKGNLSDPAWPKIPGLEDFEGEVMHSARWKEDYEFTNKRIGVIGNGSSAIQIVPKLQKIEGTQLSCFVRSKTWITNPFGDAAMVKLGLDPKELGFSKEQREEFANNPEKFYAFRKVIEDDGNTIHEVSFRDSTMQREALELFRTAMRERLAPKPEIADFLIPSFAIGCRRTTPGPGYLEALVEPNVDFITEGIASINAKGVKVKPRPGTNETEERQVDVDCLVCATGFHASSAPPFPIQGRGGQTLRERFDPHPEAYLSVAVDGFPNLFFMLGPNSAIGSGSLTRILESEGDYIVKCLRKLQREDYASMSVRADRVADWAAYCTAYFRDTVYTDPCNSWYRSGDRITGLWPGSTLHALEAMRAPRWEDYEFEHIEGGEVNSMKWLGNGWSVTQLKKEEPGSEELQGDPSWYLEPRFLDVPVEGAPEEDAEFKLRPFYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU13</accession>
    <name>A0ABR1UU13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_014511</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661013.1">
        <property type="nucleotide sequence ID" value="XM_066818825.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051885"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF268">
        <property type="entry name" value="5-METHYLPHENAZINE-1-CARBOXYLATE 1-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="10"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8062414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="415" mass="44945" checksum="DEB344A7F1F646D9" modified="2025-10-08" version="1">MPYLTTPQPRVIIAGAGIGGLTAALSLHAEGFTDIHVFEASAQLTTLGVGINVQPSAVLILRNLGLLPKLQDIGVETAELNFYSRHGHPILSEPRGAHAGYRVPQFSVHRGEFQMLLLDAARERLGEDRIHLDHTLTSYEQQDAEGTGGDSITARFTRRSDGSDAAIPSMTGAVLIAADGINSLARRLLPYLTGASMVWAGHANQKFIAYPISGRSLRAGKSLVNWIAELRVRAEGDPDVTPPVTDWTKRVPMERFAGPFAEWASPMCDRDPVDRWSFGRLTLLGDAAHAMYPIGSNGATQAIIDAETLAKCLLDQTKSDKPNDIAAALKVYQETRLPPTAQIVMANRANGPDHVLQLAHERAPDGFANIYDVIPKEELESIGATYKAIAGFEKDAVNVKAEQTEKLAERFATKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUZ5</accession>
    <name>A0ABR1UUZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ysc84 actin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661353.1">
        <property type="nucleotide sequence ID" value="XM_066819165.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052225"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11524">
        <property type="entry name" value="SYLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF8">
        <property type="entry name" value="DUF500 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="2">
        <location>
            <begin position="344"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="536" mass="55950" checksum="2E885A5B4CE2E2B4" modified="2025-10-08" version="1">MVSTQDSQPPHAGGNPPYYAETANVAGAPPSELAGDSSSSRPRPPSLPYQINLNDQPLGEDGEPYHVPPPPPGPRRQRRNNIAPLHIHAAPPSYQETAPPGSSVTFNDEKRPVLPPRPSSQPGQQGQGQVPYFAPPPTEANNAGPSQAQAPYFPPPPGQATSDAPPAAAHNEPSSSYVPSAAAIGVASSNNEKPDQKQQQAQPQGAKKKTFGERLYQWGVATGVPVNKITNKLGSEAFWPTTMDKECDKAARILKSFCKDGFYANPSCQQAPSPSPGHPTSPGPKGDSKALVKIPAEAIKQARGLAIFTTLRTGLHFSGAGGSGIVVSRLPDGSWSPPSGFLVHTLGAGFMIGLDIYDSVCVLNTEDAVRAFTRPRLSLGGEIAVVAGPVGAGKSLEGALGAGKPVWSYMKSRGFYAGVQADGTVIIQRPAANADFYGEEKITPERILKGDVKPNATAAAAPPKEGEIVMWPAGARQLMEVLKSAEGKKADEKLMSDLGSGPTPGDLATADGVHPEGQQQQQHQQAGAGLGDVKYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVH6</accession>
    <name>A0ABR1UVH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_015037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661539.1">
        <property type="nucleotide sequence ID" value="XM_066819351.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052411"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="236" mass="26028" checksum="FECAAB8FD908AEB8" modified="2025-10-08" version="1">MSQTRSRRREQWVSLCWDALRVELEQRQQAVFRVAHCLLRVQLRVAEQDVVVANLFGRSTTFVEDAPFVIIPAADILARLAARRIGSIIGTQQVLDGDAEGWTPRSRRALNKRTTLRQVDGDLCGPAKDRRRLCGGRQICTYCHAVREGKIANNTLPGRGLEHNPAVGLDGRGGGADAPFLVTRDAEVHCRDEMGGGISSAMTPATEAVLTWPKGPLLVVSSTTLYRKNITATWCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVI4</accession>
    <name>A0ABR1UVI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661532.1">
        <property type="nucleotide sequence ID" value="XM_066819344.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052404"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578:SF1">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046655346" evidence="2">
        <location>
            <begin position="21"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="489" mass="51691" checksum="D8E9FEB7B6A1E622" modified="2025-10-08" version="1">MASITLLTSFVVVAAAGADAVSLTRDRHDGVVLVLPEPRVGEDGPAATALQVNGNYADNDAVYLQKHEDENADETVLGSGPSDTDVMDTSTDKSDDGEEEGYPDLHKVTAQHSQHLRYDDNSALLYPRDTTAMVTTTTSVPCSSTSRSFEAQQKLRGSSSSSMTSMTMTATMNTSDITAAAEAKTTRCTPISWTNTFAFTTDAACPTPYEYGTYCGFVNPEDPCAKQPGGHGPRMSPDTPEVFLSYAPFHNASLRAAVPGGYRPTFVDLYAATNAPPLAHDDAKSSSGSSSNITSSASTAPCYMGYHLLPAYDPAACAALCDADPSGACAAFNLYVERDPEWNPWRCSCGRPRAVTNFKCALFAGAEAVEDAGRATNFGQGIQGSEFVRKIAGSNGGRGQKGRGLSGEGDGDDGGGGGDWDYDDGWKRSGFYSWCVDGDHADSVASCCAERRHGVVVHHDGCWGRTGFIGSTWSDLHAGRFHGGIIVCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVJ3</accession>
    <name>A0ABR1UVJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein Sm D3</fullName>
            <shortName evidence="9">Sm-D3</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">snRNP core protein D3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_015052</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661554.1">
        <property type="nucleotide sequence ID" value="XM_066819366.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052426"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01721">
        <property type="entry name" value="Sm_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034099">
        <property type="entry name" value="SmD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="7"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8062955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="117" mass="12814" checksum="789075F50D0E9A71" modified="2025-10-08" version="1">MTSTIGIPIKLLNEAQGHIVTLEITSGQTYRGKLLEAEDNMNVQLKDITVTARDGRVSHLDQVYIRGSHVRFFIVPDMLKNAPMFRSRNARGRGVGLARGRATVSRARASGRGGPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UWF4</accession>
    <name>A0ABR1UWF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660747.1">
        <property type="nucleotide sequence ID" value="XM_066818559.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051619"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF33">
        <property type="entry name" value="MEMBRANE PROTEIN WSC4, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09020)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="158"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="228"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="228"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="302"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="332" mass="35227" checksum="332832BD05E5D029" modified="2025-10-08" version="1">MANLGTLPSPFFLSADCSQQIARTYYPGSIYLLQGPPITFSGCMPQSYNPTTSFYYSASQCPSGYTPACTEYVTVETLTDTRVTCCPTQQQFTCQTRPLYDFESTLGCSTNLPVNTYTLSTVTIVNNGATTVTPITASGGGINAYGVQLRYNAAATSSQTQSSTSSSSANPSSTSSPSSTPTATDAAASSSGLSSGAAAGIGIGCAVGGIAILAAVVFLFLRGRRRQQQQPQQPYQGGPPTAPGPMQQQQHHYQDQPPMSPNSMQQQHYQDQPPTAHSSMMQQQQPIGDSHAMKSAGVYRNSHASVSTYPQYSEQPVQEIGTTERHVQEMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYW7</accession>
    <name>A0ABR1UYW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cupin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661618.1">
        <property type="nucleotide sequence ID" value="XM_066819430.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052490"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02208">
        <property type="entry name" value="cupin_RmlC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8063019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="29392" checksum="0E918AC53BE8B253" modified="2025-10-08" version="1" fragment="single">LDGALTLRALRHPHRAFAFEVTCQLDHPALVAILADPGKKPPRHFHPRQAEYIQVLQGRAVVEVEGHDDASAAARHRVLLLAGTDGGKSEEEGGDDFCIPAGAHHTWYPSAARVEDNDEDDGGREVGDGGGSSRRRNMRMTRVVVSGEATPELFRLDWAFFENWYGYQDLCFQKGCAPDLIQVMCMFDAGGSYLSLPSWVPFGRTVAKAVGVALGRWLGGLLGYQPYYREWTTDWQVACDKMETCWFYRRLADRRGKSDSKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1B9</accession>
    <name>A0ABR1V1B9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8064989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661743.1">
        <property type="nucleotide sequence ID" value="XM_066816051.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049111"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="1">
        <location>
            <begin position="9"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8064989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="300" mass="33566" checksum="CBC886F5448C5A1F" modified="2025-10-08" version="1">MAVLDEIPGIGVVVRVGGLIVEEYHVPAGSQELVRTICPFTYTYIVSSDDTEFSVGIAVDELYDFSRSEDHRLHFSVTVDGDRLAASCGITRENVRAGYGRARDSVVRATSFDARRGYSRRQPAKPLCEGRNREWRKGLGNHRVRVYRVVRRKPVGIRSGPSLFDCFNVAEMARTGNDTTELERAEPPINVQNAGNGIWFERTWDPLESTDFCTAREDTFIIPPSPPLPPLPAIRGGQNVIVPPGRERHQRQQQQATVARNVGQEHEAPRTIVKRELSEMGVWFMTAPGPVDLERGRGVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1G8</accession>
    <name>A0ABR1V1G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EKC/KEOPS complex subunit CGI121</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">EKC/KEOPS complex subunit cgi121</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011769</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the CGI121/TPRKB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661776.1">
        <property type="nucleotide sequence ID" value="XM_066816084.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049144"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2380.10">
        <property type="entry name" value="CGI121/TPRKB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013926">
        <property type="entry name" value="CGI121/TPRKB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036504">
        <property type="entry name" value="CGI121/TPRKB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840">
        <property type="entry name" value="CGI-121 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840:SF10">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08617">
        <property type="entry name" value="CGI-121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143870">
        <property type="entry name" value="PF0523-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="126"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8065022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="222" mass="25165" checksum="264EE460316F5157" modified="2025-10-08" version="1">MATAAVEKVELEHLPATHTVLLALYRNVVNAGFLQEQLLGRNADFEYAFVDASTVVSRFQLLTAVHKAVTAEMAGTMRTPNVHSEVVVSLSSNNNVGEPMQSCRYEMHDQLTRYTTTDLRSLQEIRRPARHQRRGRRQSAHIPRRRPSSLSPDDVEKHLQTHVQGESVPCSDEELARVTDWPKLRKYHKLSGLPWIDAIKDEQAKKNELEMLIVSAMAMRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1J3</accession>
    <name>A0ABR1V1J3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cation efflux protein transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011801</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661808.1">
        <property type="nucleotide sequence ID" value="XM_066816116.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049176"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF13">
        <property type="entry name" value="CATION EFFLUX PROTEIN CYTOPLASMIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="8">
        <location>
            <begin position="142"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="427" mass="47124" checksum="79BA43412ACC5648" modified="2025-10-08" version="1">MSDAPGGVQPVGPAAAANASDAKVHGSTANHDVGAATATTTAANGDAQEKAQDSAASPVSPSALEFGNGLADPLDIGRHRRDDVTLKQLQIEYPKANKRELRKFYRNQNKLINHYLGVDDEERLQVEEDARLGPKIKFAINASFTVNFCLFVIQLYAAVSTGSLSLFATAADAFMDLVSSCVMLITSRMAARASIYDYPVGRTRIETMGIIIFCALMTCVAIELLIESGRTLGNGHTDSSEQLHVVPMVCVCVAIVAKATLMLYCFAYRKHASVHVFFVDHRNDIAVNTFGLIMAVVGERFVWYLDPIGAILIALLILFSWVSNAFEQVWLLVGKTAPPDYISRLIYLTITFDDRILKVDTCRAYHAGQNYYVEVDIIMDRYTPLEISHDVSQALQRKLEGLSDVERAFVHVDYEDDHDVNEEHKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1L2</accession>
    <name>A0ABR1V1L2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011817</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661824.1">
        <property type="nucleotide sequence ID" value="XM_066816132.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049192"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="167"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="201"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="365" mass="40215" checksum="BC84A25F37D33867" modified="2025-10-08" version="1">MHVAALFGRFQALNWLIRYKFRGLVSVALEQRNNPLLETPLHLALSQVLATEDNEELNALEELIGQVESSGVLSLQNYLNETPMHRLAASGLNERARRKGLGTILTHEKKCHYPGKYIDHLGRTLLWHATCSGRVEEVRQLFETLPQDDHTGFVDNNTVIVNQSDNYGISPLHVACRFGYTEVVRTLLKAGAWPNCVTSDPGFSPAHYAALFNHAGCLELLIEYGADVCQSTESMDFVCKPIHLANVNNFSRVQEILVAAGSSQYDLACTHHIINNDHASGCADGTTELYPAATDASLRLALYKIPTKPDSPQHPAGEEVLGEGTLFDGLQSPVTARARFQEGVKSLVQSDSDSGREASAWKYFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3E6</accession>
    <name>A0ABR1V3E6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase family AAA domain-containing protein 3A-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662470.1">
        <property type="nucleotide sequence ID" value="XM_066816778.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049838"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="635"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="883"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="917"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="928" mass="105239" checksum="485DB50ED868AC6E" modified="2025-10-08" version="1">MEGIQTESQHPPLIPEVAVAHKELEPGSGQETRNEAEAEAERKPSQRGSAEGSPCSSPISSAHPSVPSGPGDDRSPSPPPPIWSHWISREPEIRKRTGVDWISAYEQEMYEPDLDQFVVLYAFYDKDVTTPRLDEKLDEDDGEGSVGDAWEDDEPMKIIIRSLYVLNELKEVTGVAFPYRECILPDSRNQEATSISGKPESKSEVVRGREDFVVIHPGGARASAPMGDRQRPPPQHQRRLILSEEEQLRRRIAHLEMLVGFGEKALKRHLDLRAQIQEATLQRIAFNDLWHLYNPGDLLLTDERGYPQLYMVYNVTGGQPRLRNPTENEIRNRGVRVIPARRRIGRRGPRRGWYDAAEGSGSYSGSSSDAYDTTMHDAMVGTCTPFIIDCYAINVDSTGVGALCSRKQIRKYLGLKSVSDLPLYPLKFHKDAQSILAKLQDRGRKFISCTGHRRYDGVTYDTRGIVSRERLQGEIYVDADEYARSRSRFVRTELCLVKRTNPVPAEVEEAHPNIPGADFYRHHDHAVDQRKSDVFIEKDPGIQELMTRDEALLMPEKLQLMQHSLQAFSFKSRSWDKSQAARESGFQDLSIPSKHRRLLLSLVDNHSIRDDKPEDHGRMNPKPSTQLDLVRGKGLGLIILLHGPPGSGKTSTAETIAAHTGRPLYAITCGDLASERTSGGAVLLLDEAEVFLMKRDWKDTHRNAMVSMGVHENTVFLRTLEYYQGILFLTTNRVGVIDEAFKSRIHVSLRYPKFKLKSTLEIWKSTLNRIERDNELQDIKVEFDRDELLEFAEEHFETHATTDGSTWNGRQIRNAFQTAIALGQYDRMAKIQKRGLTPEEAFLSGKKKWRVVKLTRKNLEILAETARDFDKYLKSVHRRSDGELARAEDLRDDDFSEFEEEAVSTKSARAKPISESASDEESDEESDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3K1</accession>
    <name>A0ABR1V3K1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7702 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012508</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662514.1">
        <property type="nucleotide sequence ID" value="XM_066816822.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049882"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056119">
        <property type="entry name" value="DUF7702"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109">
        <property type="entry name" value="UNPLACED GENOMIC SCAFFOLD UM_SCAF_CONTIG_1.265, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24800">
        <property type="entry name" value="DUF7702"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7702" evidence="3">
        <location>
            <begin position="10"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7702" evidence="3">
        <location>
            <begin position="209"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="363" mass="40038" checksum="A4D0A7C205B1D8ED" modified="2025-10-08" version="1">MGADHSIFGFRHGIAVAQVALFAASLAIGVYFYGLERLGIPRRNGWFCVGVFSVFRLVGAGCMLGTLANDDDSVWAGVFVCESFGMVLIVFLLLELMQRANNAVPTIDPRAFYIPQLLTWADLGLAIAGFASAARRENEHPLAPTSLTRASFGLFTALYLWIAGMAYLLSFGRRAQRRRDNGQLSSSGEGEGEVYQSQSQNQGQGEGYNKFPRDERRALGCAVVCLPLLAVRTAYSLVFQITGDMAWNAVKGRPAPYLLMTFLPELAIIYACVLTIMRIAPPPPPKEEKNKEKEGAAEKQDKEQTTAKGIILSWLWPSRWQQRRVGGGGYSEYFSPQVDGGEVRGSRPRRLDEESISLVPSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3W2</accession>
    <name>A0ABR1V3W2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662643.1">
        <property type="nucleotide sequence ID" value="XM_066816951.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050011"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="103" mass="11658" checksum="0CEF755856F65DE0" modified="2025-10-08" version="1">MEGTEAADQQQPTMQNINKKGGSGPRNFSGPARLKSVRKPFAMHFAQICELSWKTNRTQAVQKRKTEDNEGDKPKKELISQDSSHLHYDPCGAEIRHKKHMPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V470</accession>
    <name>A0ABR1V470_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">60S ribosomal protein L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012454</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662460.1">
        <property type="nucleotide sequence ID" value="XM_066816768.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049828"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="5">
        <location>
            <begin position="74"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="17607" checksum="AF687AD6E1D5C132" modified="2025-10-08" version="1">MPPKFDPNEVKVITLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVQLTIQNRQAAVSVVPSASALVIKALKEPPRDRKKEKNIKHTKSIPLDEIIEIARVMKFKSFSKSLEGNVKEILGTAYSVGCQVDGRSPKAIQDDIASGAIDIPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V529</accession>
    <name>A0ABR1V529_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013057</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663063.1">
        <property type="nucleotide sequence ID" value="XM_066817371.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050431"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051299">
        <property type="entry name" value="AB_hydrolase_lip/est"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46640:SF1">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46640">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047048918" description="Fungal lipase-type domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="4">
        <location>
            <begin position="108"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="355" mass="37739" checksum="22ECF2FC2ECAC2E2" modified="2025-10-08" version="1">MKSISWSLVSSLALAAVASPVPDSLRPYLAHRQNAVTAEEVSRLDFYAEYAGASYCNSEAPVGSTVTCAENVCPDVTAAGAVVTATFAGLVTDIQGFLSTDPKNKVIVLSFRGSHSIRNWITNFVFLQEPCGLVGGCLLHAGFAGAYKEVAEPLRTALAAATKANPDYKIVFTGHSLGAAIATVAAAYERAAGHAIDLYTYGSPRVGNRAFVDFVTKQAGLEYRVTHLADPVPRLPPIFANYRHTSPEYWLSDGEATTIDYTAADIKVCEGYANIKCNAGQLGLDIDAHGHYFTNIAQCGPDGTPFKRDAAVALSVDATVPVGLPTLSDPELEVKVNDYAKQDIEAAQSLNDIWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5R1</accession>
    <name>A0ABR1V5R1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Ubiquitin-like protein ATG12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013269</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a conjugate with ATG5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Preautophagosomal structure membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ATG12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663275.1">
        <property type="nucleotide sequence ID" value="XM_066817583.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050643"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01612">
        <property type="entry name" value="Ubl_ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007242">
        <property type="entry name" value="Atg12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385">
        <property type="entry name" value="AUTOPHAGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04110">
        <property type="entry name" value="APG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="4 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="149" mass="15986" checksum="1BA225632BFF04FE" modified="2025-10-08" version="1">MEYPDVPERNNSPSPPPSPILDRPASPELPLTMTASAVLTALPRDASSALASAGDQLEQPEKVVVRFKAVGSAPELSREVRKITASQKFEAVVAHLRKALRVAPTEGLFLYVNSAFAPALDEVVGNLHRCFKDSSDQLVVAYSMTPAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V636</accession>
    <name>A0ABR1V636_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NAD-dependent protein deacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013404</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663410.1">
        <property type="nucleotide sequence ID" value="XM_066817718.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050778"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01412">
        <property type="entry name" value="SIRT5_Af1_CobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027546">
        <property type="entry name" value="Sirtuin_class_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF10">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="306" mass="33516" checksum="169162FF4F52F050" modified="2025-10-08" version="1">MPRAYHRPCTDIAEFQRLLKHSDRVLALCGAGLSAASGLPTFRGAGGLWRNHQATSLATPEAFKKDPALVWLFYAWRRHMALQAKPNAGHYALAELAKHNKDFMCLTQNVDGLSQRAGHSPDMLRMLHGNIFDVKCFDKECDYIEPNNLSDPLCPALAPASERYPADQTMPLLDPTKPTPKIKREDLPHCPTCKAAGKTSLLRPGIVWFGEALDSDMLKEVDAWVAKPRGIDIMLVIGTAAAVYPAAGYTDAARKKGARIAVINPDRSAQKGLTSRDFYFEADAAEILPKLFEGIIGKPEIPGQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V700</accession>
    <name>A0ABR1V700_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Anaphase-promoting complex subunit 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013718</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663724.1">
        <property type="nucleotide sequence ID" value="XM_066818032.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051092"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF9">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="469"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="503"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="620" mass="69472" checksum="4E995EAE9C3DE403" modified="2025-10-08" version="1">MEKSNMEKFLRDWRQDALNKAQYESAIFIGDKLLALTNHDNDAFWLAQVHFATGNYTRAQAFLSKQDLISRSPACRYLAGHCFIRQSRYDEALAVLGERNPTHLITNPAHKRKVQHNGGHAKGATKALKGSDSSDEDVANRRFEAAMCFLRGICYAKQNAFDRAKECYKDAVRIDVQCFEAFQQLMKNSLMSPDEEWQFLESLDFDAITVSGDPSSSQEAAEFTKMLYTTRLSKYRHPGAFTTAAETLSTHYNLASNPDLLLARADLLYTQCRYKDALAITESVLHGDKYNFSIYPLHLACLYELKMKNVLFLVAHDLADSHPEEPCTWLAVGVYYFSIDKIAEARRYFSKASMMDAHFGPAWIGFAHTFAAEGEHDQAISAYSTAARLFMGTHLPQVFLGMQNHALNNMTLADEFLKTAYGLCKTDPLLLNEMGVVYYHQDRPQDAATLFLKALEIAEDIDSEPSAWLAARTNLAQAYRRARRFEDALEQFDEVLRLGGKDVAVFSAKGLIFLEQGQPEEAVVVLHRALAISPQDPIATELLNKALEESAGIDLPSDDAQTEALDGLERAVRKMKGPPTVRIPGQPGILSRGKGRVARGNRRIMGLRDDDGAMEMADDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7P0</accession>
    <name>A0ABR1V7P0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663089.1">
        <property type="nucleotide sequence ID" value="XM_066817397.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050457"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="19889" checksum="88C379B7ED6D5D7A" modified="2025-10-08" version="1">MASDKETTADRSSVLRSCAHAFCQALISPPSPKELLSEFFIPDPPGGEVSRPTIHEHGPSWATKQLPFLGKSFTGGQACEEYFAVLSDTLKMHLGPDSFPGLEGFVVDEAQNQVCVVGKGRFESFRTGRSWDEQFAYVLSGWDEQGKKLGRWDIWADPLSAWAAVAEDDMDGWKRGSTGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7R4</accession>
    <name>A0ABR1V7R4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663984.1">
        <property type="nucleotide sequence ID" value="XM_066818292.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051352"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="267" mass="30331" checksum="F7B45F7CD686F993" modified="2025-10-08" version="1">MAAASGGRPRPPPRPSRRQYHFPPNIISSIYKAYLDRYPGDTRCSSRFARVSRAWAHEVEQRTFRRLVVDMSTITTTTAYPMNSVHHRNSLYMGTSYSGPWGDDDLTKFEFYVRGPRRAFLRELIFILPDPMKDVDACNAAMRRLFDVLGAWGLPAPMQRAYIDLEIFITDEYADLHHNRPLSSDFLFKAGRQTPTTVQHGEHEPYPEPTARPAPLLHGIRGEALRLRPGPAPRPGRRVAGAAVSLSGRQPAGRQQQHVRRRGQYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7U2</accession>
    <name>A0ABR1V7U2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664011.1">
        <property type="nucleotide sequence ID" value="XM_066818319.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051379"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="247" mass="27808" checksum="342BB1623D35B5B0" modified="2025-10-08" version="1">MSSYHTARTRSTNSQPTNHGVPNHSPSTSGEHPSPLVDRDGRRLPQHRLVDQDGRRLPRRSTIPERRPPPVQRLYVPYRPPPRVVEPQPQRPAEPPNWVNNYNRYSVGGEQDSYYATFERHESDPAYDARPHYDHPHGRQSPRPSRASTPQSGRPQTAPEPARFQGPAPQAARRPSFWTRLLCGSQDGGSTSRSTAFDETRAARPVGPSASTRRRARHAGDEDDPYRVVVGYDAETGRTYYGSRYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7V2</accession>
    <name>A0ABR1V7V2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Fatty acid transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014022</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664028.1">
        <property type="nucleotide sequence ID" value="XM_066818336.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051396"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="67"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="6">
        <location>
            <begin position="466"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="601" mass="67297" checksum="06AA815CF9441A0D" modified="2025-10-08" version="1">MNLTGASAAIGTAAVAAYLDGKYHIREDLSAPSPYWRILKLQLLMKRKQWADKLTVYDMLHDYANSSMGDRLFLIFEGRTWTYAQFFAALQPVGNWLINELGVQRGEVVAIDSGNCPEYLMLLFALNGIGAAVALLNCNLTGKALVHCAKIASTRYILTENHVQHLVDPVEEELAQSGCQVVRFDRHKLENLPDTGPIPRSRRAKLDFTDLAVLLYTSGTTGLPKGVATTRFQQVVLSHGAFTNHLRMGPGDRMYTCLPLYHAAGYGLCILSCIGTGAAVALSRKFSHRTFWPEVHASGATHLQYVGELCRYLVRMAWGNGMRPDVWEPFRERFGIECINELAIAVRGPLWHLKNYGLETRARIDPETQDLVRGADGFAVRARRGEAGEMLYWASPANPASASPYYKNPEATQKRYVRDVFRKGDCWFRSGDLMRLDAEGRLYFVDRLGDTFRWHSENVSTNEVSDMVGEFSQIAETNVYGVLVPRADGRAGCAAVVVREDVGGADGVDWKALAVHCRARLPKYAVPLFIRVVKELEYTGNMKLRKEGLRSEGVDLEVMEKNAKEKGKEPDSMFWLPPGSEEYVPFRHTDLHELRGGRVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8H0</accession>
    <name>A0ABR1V8H0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fructosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663026.1">
        <property type="nucleotide sequence ID" value="XM_066817334.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050394"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="307" mass="35357" checksum="707D1F7899281A9D" modified="2025-10-08" version="1">MPASPDWDGAPNWDKEPEVSEQYIRYIDINVQAGDDGKGMMHGEYESMKVLHKTMPELVPNPIAWGTYFTAKDIHFLLCEFHDMDEGPCSLDTLPELLAELHKKGVSPTGQFGFPIATYQGRLPQDPTWCDTWEECFSRNLDIMFEHELQAQGPGDAELAELRRTVMTRVVPRLLRPMESGGRRVVPRLIHGDLWEGNAGTDRATAIPKIFDACSWYAHNEFEMAPWRPARQEMGKPYVDAYIQHFPPAEPTEDFDGRNTLYALRFNLCSSALYPGNLNYRNVVKSDLRELVKRYPETFEEWQERQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9W6</accession>
    <name>A0ABR1V9W6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663597.1">
        <property type="nucleotide sequence ID" value="XM_066817905.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050965"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="637"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="751" mass="83257" checksum="3E762E5C42385813" modified="2025-10-08" version="1">MCSNEEGGGEDADTLRDNVSVSSLGQSITEQSETTLRDSTRQDASPSHHSERDNTETEDGQQTELLFLDSFRQLKRSKSIASSLKVRDGYGTGTWYRFSYWATEAWLYEFLAWLISCYCFGGIVITLLTHNGQPIPEWPFDITINALVSAMSTIMSSALLVPVSNAIGQAKWSWIVKRRRKLEDIAVYDEASRGSWGSLVLLMKKGFRDPVAFGAMITILALPIATLLQQTTVVVLEKRPLENSTATLFALNWWAEGLSTESGHPRVKDDMVMSINRGLFFDGNVSDPFLTNALRPRPQCQTGNCSFGTFESLAICSECQDITQSLKMENSTTGLECEGDKAGDYQQDCARWSLPNGHNSGWVNFGSGMLLSTNASAEPIHPRPGLSILTLTALAPCWNYTYTQRNNSYHYKACIGKDEPGSQQQKKTQAQECTLQWCVNRYESEMVNGVLQESIKSTIRSGEPTPGLMYDFSPQNSSVSYWVDLHPIKVSAGTVLGYGNIRSGLIRGKLSVHRQASELVTTYLKSELEGTTSVNDTYVKGGKPYIRRLYMAHLGKYEGTNVPRGFDMDPLFGTMALSMTSSLRTTPAGSQAQPAGDDGNATSDDYEPDEDSWDFPTHWQNISTAPDRLVPVLSVRWGWVALPAALELLTFFLLCYMVGWKSQRSLPVWKSSTLPLLLLGSEMHDGSGDNIPRHLVDMEQLAKEATIEPEIAMGRGHGPANKNLEDGWNSEATRSWNRKYSVGHSTTEVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGL2</accession>
    <name>A0ABR1VGL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664184.1">
        <property type="nucleotide sequence ID" value="XM_066814894.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047954"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="279" mass="32223" checksum="FEC293C06E3FF0CB" modified="2025-10-08" version="1">MAPTPPPTEAEVQKRKLGEADAIIKSWKKLRKFLANPKARDTIVKNWRNSSKPKRRQRLRRGWEDSADAEDAEDEEDGAYSKRMLERHRSDFDGILSWKPNRNYEKVPATLDEMREPSKQTYGEWLANMNSYKVECANYNAKDFSESHGPLLELLYTRAAAAPSAFYESDKNAEFLPFRSLTSPLSREPDQVDEWVDLGRDPRSGRSDAYGDVQKADTAEERNRCAEQGMQELEIAEWMMSYQSRIYDFMLAMCQKVGGDNLFQQTMGEGEGVRRREAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHG9</accession>
    <name>A0ABR1VHG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nonselective cation channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010896</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664501.1">
        <property type="nucleotide sequence ID" value="XM_066815211.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048271"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF1">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="454"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="483"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="540"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="3">
        <location>
            <begin position="73"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="299"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8070693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="917" mass="104293" checksum="B94622A5F732F4D6" modified="2025-10-08" version="1">MSDFHLFSPKSFELGRSNSGSPTTQQGPNPRFEDYESSSIDLETASNLRPDSRHNVSRAGSSRSSSIADSPSVYKTIHRVRRLVIATLDDPYTLDQLREPRMNVVVVRPLVNRLYDPDDPWMVYCLLANRIQFLREQSSTAHQTVSIARAALCELVATRILRRFNEEHSGPIGLLLLSHILVNGFDPFQGAPIDIEIEHRRRQWPIQKRHGEPERRLTTLELAIISESKVFVSSFACQKVIDAVYEGRVVYTPISFVDILPDHYESCPISLYDPRQAPFLDQTRLTVPRVRNFIELSQFLVLVCLYILTMMHRSSSQATVFEYLFCIYASGWCVDEFASMIDHGWAVYSQTLWSFLDIAFISIFGIYAMCRLHDGSMGTMADGYGMQALCVAAPILLTRLAFATIPDNIVFISIYAMLKDFTLVTFLAIWCFTGFLLSLLWLNSSASAPDENPAWATVCKWLLWIWFGLDGTGIDHSAEFHPILGPALMTAFAFLGNTLFLTIMVAVLTNIFSKIIADAPAEIQFRRAVLTFAGVKSDAIFAYPPPFNLLALLFLLPLKAVLTSRKFHEVNVFLIRTLHTPTLLLIGYFERRSTWAGSPPHGDIQAVFQAPPPEDVQNEIEELDALSDVGYAESELISPRSLSRRRTPRTARRRGSKLPSPPAIFPLSSALGGNLLVSRVPAPRVPRQFRPLNKKEMAELGKHANDRLWPYLNRSKDYWWPWPWQDTGDITMMMSSAVGWLAGTGAIDDYELATTYKWNTKFPFQDPVKVVLDVAYRGDAIMRGLGSPSENVKEGEMQQWYTRHYLVSSNWDMGAVVEIQNSKPRPGTIDVAEVQALLILLDRQTVYVLEKQKLRAWVVSMKRGFFRVLEAYLDQSVDRFAFHFSIRSERHFRKRKALDGNDEEWKWLLSWMLAQPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHK4</accession>
    <name>A0ABR1VHK4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664165.1">
        <property type="nucleotide sequence ID" value="XM_066814875.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047935"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="135" mass="14665" checksum="6BF6E3873EA56AD6" modified="2025-10-08" version="1">MTLASRAPFTVEPCMQSEDRRHLPRNQRDSRVDDSRRCDLTPTALHHGGMHICASMNVLSKWAQSPSSMSEVITTDLGDVLYSYSTLLYAVSRLCLWSLAPIGGDSPTQAGGAGLALRVQQLECGDQQSCAALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VII4</accession>
    <name>A0ABR1VII4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial</fullName>
            <shortName evidence="7">Glu-AdT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011254</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664859.1">
        <property type="nucleotide sequence ID" value="XM_066815569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048629"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF7">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="9">
        <location>
            <begin position="45"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8071051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="517" mass="55803" checksum="C4CF9A7CD2C5866A" modified="2025-10-08" version="1">MLPEAEKDTPTTISIIESTDEDQCLHRRSGRSSPPPPPDASRIRLAVKDNIAAQGLPTTCASRILTGHEVPFTATIVAQIESRLGAELWGKTNMDEFGMGTHSTNTPYGSVHLLEGRSAGGSSGGSAVAVGLGQATVALGTDTGGSIRMPAAYTNTVGFKPSYGMLSRWGVVPYANSLDTVGLIAKEVAPIQEIIQAVCMEHDPKDPTSLPATVRERCVAERQYYPSSRSTAPDLQAQGLRGLTFGLPIEYNIEELSPRIKEGWMQVTDKIKEQGGRVVPVSLPSTKSALSAYYVIAPAEAASNLSKYDGIRYGKRASASDSAEDSDTASSDALNGILYAKTRGEGFGPEVKRRILLGSYTLSSEAVDNYFKQAQRVRCLVRRDFDRVFRLSNPLLENEHDDGSNEQQQFDLSDMDESVPLESKFGPTQIDFLLCPTAPTTPPKLSDIAKQTPFDSYMNDVFTVPASLAGLPAISIPMALPKSEEDLVDFGGVQLIGQFWDDARLLAVAGHIRSKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VK83</accession>
    <name>A0ABR1VK83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664448.1">
        <property type="nucleotide sequence ID" value="XM_066815158.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048218"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="452" mass="51873" checksum="75CFB7DB9F0FC9B5" modified="2025-10-08" version="1">MFTGTVCRLPTFAQPAICKEESLYEHSLDVGSLFVASSRSANAVGKFYNHACVSSGDTKGDTKLLHTLSSFGQHDTWILPDEDDKGSKDFYYRQSQTDELLRAEARRSASYRKTSADLNDMCMTILEGHKEGMQTNRDLAPTLYETTGLSARLRHLMRISTIDEKRVDALARAFLARRDMTFETWAAMRRHIRTTLESLASLERRNAQISKTAARARGKVASDLYHLSMFRMDNLTEPVATFDLWSLLRNPMRVVRDFAAVTKAEIAGFEKSLEHVQNTARQGQYSMDDIRSLLNGFDEDLRRLERAFDFMKPVTRQALLEDWEQNENRIALKGSAWRQTLIKHYGFKTWASIFFMDDEWQVRDLFVLLEMVFEPILIVVLVLLWNPIPDGGLWYYPQLCLGWFGCFALFVFCLDVLGALAEDSIWDALYPLKLLWAFLPDLLAYLNGDLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLJ6</accession>
    <name>A0ABR1VLJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetyl-6-hydroxytryptophan oxidase ivoB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664913.1">
        <property type="nucleotide sequence ID" value="XM_066815623.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048683"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="3">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8071105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="341" mass="38749" checksum="EA18C0B979BC7725" modified="2025-10-08" version="1" fragment="single">RTLTTDERQGFIGAVRCLQSKPGQTSDTFEGVKSRYDDFVALHITQTDYVHWVGQLLPWHRYYLWSFEQNLREMCGYKGAVPYWGELGFEYFRNTERRTDSPYVRTDWTQDAVSEKAVVESPIFDPVHGFGGNGPYIANTTGFPQDWQTMTPVPNRTGGGCIEDGPFAHVNISMGPGNHTGYTPHCLRRDFSPWLVTQALNASKLAFVLEAEDFWRLDHRIEGFSLEIQDMSLHGGAHLGVGGNIGEMANTYSSPGDPIFWLHHSALDRVWNIWQKQDWETRKGDIGGPDTQWAYPYNYFGGIPYKNVTLETPLHFEQIGGTLKIGDTMDIHGGPFCYDYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLV4</accession>
    <name>A0ABR1VLV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal protein L37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_011036</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic ribosomal protein eL37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664641.1">
        <property type="nucleotide sequence ID" value="XM_066815351.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048411"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00547">
        <property type="entry name" value="Ribosomal_eL37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001569">
        <property type="entry name" value="Ribosomal_eL37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018267">
        <property type="entry name" value="Ribosomal_eL37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003214">
        <property type="entry name" value="PRK04179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01907">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01077">
        <property type="entry name" value="RIBOSOMAL_L37E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8070833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="99" mass="11311" checksum="19BFDDBF69C52495" modified="2025-10-08" version="1">MTKGTSSFGKRHNKTHTLCRRCGRRSLHIQKHTCASCGYPAAKTRKYNWGEKAKRRKTVGTGRMQYLSGVSRRFKNGFQSGMQKERPGPCPEGIDGRHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTC0</accession>
    <name>A0ABR1VTC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665460.1">
        <property type="nucleotide sequence ID" value="XM_066813498.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046558"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13398" checksum="0A6BDECCABAFFA9E" modified="2025-10-08" version="1">MATDRQTVRDQGDRIGTKRQLANEAYIVGWICAISTEYVAARVFLDDEYESPEHSAQHDNNSYTLGRIGKHNVVIAVLPDGEYGTASAAIVAREKDVLCFEMEAAGLINHFPCLVIRGSAIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTK8</accession>
    <name>A0ABR1VTK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009258</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665535.1">
        <property type="nucleotide sequence ID" value="XM_066813573.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046633"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.350.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032382">
        <property type="entry name" value="AltA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16541">
        <property type="entry name" value="AltA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51895">
        <property type="entry name" value="AA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046066404" description="AA1-like domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="AA1-like" evidence="7">
        <location>
            <begin position="28"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8074595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="264" mass="28415" checksum="DF27E1B7310E0391" modified="2025-10-08" version="1">MQIAVAAAIAALFGFATGAPAPAPQADDVRETLTLSSFSAHKVLVSPRNSTAATVDSLSYKLTGTREEGGFGVACTAEAAEGSGEIIYAPQVYNCNGDDDHDYYFSVVSVSDKDVFTLNVFREVTFGWGYQAQIEAPTYCHAGGNNSMSCVQAGTPGYGYIARAQLRSADFPAYNPGSWLNQCHVDWHTSGGPVVSSIEHMWKKEVLVSPRTRGKYTLRVEAFAQFTSQSPNAGPGVRPQIRRVGYPMNENDRTVAYAGNMVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUT2</accession>
    <name>A0ABR1VUT2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009673</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665950.1">
        <property type="nucleotide sequence ID" value="XM_066813988.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047048"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00842">
        <property type="entry name" value="MPP_ASMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041805">
        <property type="entry name" value="ASMase/PPN1_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF27">
        <property type="entry name" value="ACL091CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046973784" description="Calcineurin-like phosphoesterase domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="239"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="714" mass="76813" checksum="030D6AE324D20785" modified="2025-10-08" version="1">MVTSSLRTTTVLMMMAQVVLAAAATTSMPGLASFTVPAAFPTSVFSSYYVKPGPTQEPQPALYDPILNKTFGLGVTDPLNIPTHDTDPVHYPKAFAELSDASAEAVIAAAKAEILDILKAGHPGLTSNCSKCVAALSVGQIAAKLAPTYLPDAMVSLCKETAFASNSTCQAQYEAGSFGATWTQILSHAEVTGLDGQFICAALGSYCPLPNKTDTFTAVFPKPKPAQAKKPQRSNKMVKVLHLSDLHLDARYEVGSEGNCTSSMCCRHPAPRPGSDGDGGGAAAVPIQVPAPLYGYYKCDSPYYLALAALQSIGPLTGTSPENPAAFALYTGDLVAHDPQNQRSRDYVEDIELSVWHMLKSYIGGPVYSALGNHDTNPDNLDVPHGIDDNGSLGQQLSWNYDHVSSLWNYYGWLDNATAAEAATHYAAYSVVPPMSDGGLRIITLNTDLYYKNNHFAWLHAADPDFSGMFTFLIQELQKAEDAGQRAWIVGHVLSGWDGSNPMPNGSDLLYQIIERYSPHVVANVFFGHTHEDQAFVYYAHNGTGGRTAETAIASAWVGPSLTPLTNLNSGYRLYEVDTGTWDIHEAYTFYADVDSFQDLDPAAQAGPVFQLEYSTREAYGAQAGSGPEEGWPADAPLNGTFWHRVTEAMERNRTLVEVINGFQGKSSVRSPNCTSDACAEAKICYMRSGSAPMGRLCPQGFGSVQSPYTGKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUZ5</accession>
    <name>A0ABR1VUZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009734</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_066814049.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047109"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="32293" checksum="91360903E45A608E" modified="2025-10-08" version="1">MAGSPTGPSRKEQSTAATARNSSSCRRPTGGATPPSVAIPGAKPTHHPNIAISPILPSHIPSLRRITARLLPVRYSDSFYAALSDPDSSGAFSRVLLWTDENDASNNKPTVIGGLVCRPEKLYQPRPDEPFVDAIPNALYIQSLVLNEPYRRLGLAGALLNEVCGLAARDARWACRTVCAHVWTQNSEGMACNINGQSTAAMTNGGSEAASRATPAVMSFTNSSPLPSPNGPPPMGGPPRPGPSPNPASGQSFQNARPETEWNDLPAEMSRTLAVPGSGVSSGASSRSSSTLRKKRDRAYPAAAFGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW33</accession>
    <name>A0ABR1VW33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MUC1 Extracellular alpha-1,4-glucan glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_066814030.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047090"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="927"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1473"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
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        <location>
            <begin position="199"/>
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        </location>
    </feature>
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        <location>
            <begin position="216"/>
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        </location>
    </feature>
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            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="629"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="652"/>
            <end position="667"/>
        </location>
    </feature>
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        <location>
            <begin position="691"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="726"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="774"/>
            <end position="785"/>
        </location>
    </feature>
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        <location>
            <begin position="793"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="938"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="993"/>
            <end position="1005"/>
        </location>
    </feature>
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        <location>
            <begin position="1030"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1088"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1238"/>
            <end position="1249"/>
        </location>
    </feature>
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        <location>
            <begin position="1283"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1392"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1544"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1555"/>
            <end position="1572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1572" mass="169665" checksum="CC8EB0896BB02AA9" modified="2025-10-08" version="1">MFGARRNRRGRGPPNPHSTPAPVNPNASTAAAAAFMSSQNPNRSLSSAAAAAALRARPHTPTNVGAVQTKRTMRRSPSISSVSSAPAGGRRTPKLERRGSSGSMTERTFRSPSPHGREPQSQSQHPPVPAIPDGHRNSAIGRSPSAAGVGMQNFRTASQKMSTELPSWYTKPSGDTSNVRTSDAPMNNTGRSSRRPESLASTARPDSQNSVNFSYPSRVRATSPSPSPSTDRTQQWGISPSNSNRTSLPASFSGNSDQALVYDPNSRRMVPRTDRLDLMEVSYHTKEVSEKRPKKKKQGVQRSGSHLSKGTVARVKGTTVEPSEQERGFPNRESPVVATPPNGRDLPTNEQPYAEANATNATASHLDWAQLSQDQQLQQEESNIQARASAVQVAEVPSDRLVGRKPSVVREVPEEDATSNGVRQALDSVPTQQTLYSMAEDASESSSSAWNEPQAPSEFPREVPAEQKVAFVPNKPVAELSRNGSTSRSASNSPARTARFAATPSENLAVRHAPLPRSASPIKSALKHHDPSTRDASPSETGSDMRVTSEREVSVARKKSVRVSFDDHNTRIVGESAPAEDEDPPAAPSPQQVKRPWYSNIGKNKKKDFSLDDDEIMKPRPALPSFGSIREKKLREPEEERPLIRPSGPGYSPARPSSPSMRPSGAGFTFSADRRDNATIALSNDHAVGSILTQEQSSRNAANISRFREPLPPVVTSAEAHRYDSDSASSYSEDGQSNDELSGGSDGEMIPSTQTTMADSHDNLESVPTIPNKSPDRTRHTEPQKAIELPDNQVPSISITNPSPAIMDKSHPSESKSNHQQYFEVPGKFPDEESEEARSLGYTTAKSVGPDDVPRPTQAVRESDAKAHPAQTPALPQKTLARGAAAADATDSSDDESNASIYSDAYEDLSDIEGDGYQSLNAVVESPLSKESKTAPVEPAPIEAPRPVEPMASEPMGDHLLSKVIKDAEGSTEPTQGVVNDWETAKSYWRSLTTEKRRQLEREAMIEAGDDADAETPTRRPSNRKKTAEQIKSTSVAQMAHAQSPTSGSRPSQPTNPERIYLVQPGTKATEDSYSPTAPSGRMRASLRTEQPAKQPQSSRPVSSEVHMRKSMRGATTGEDADGRASRHISAPTERPNSMSKTTLRPQTAAPGKKTTNSALASASAGNAITKSSKPALQRRGSDASDSSFKRSRATSSGGFGFRSTMRQGPTSEAAAPAERSSGRFSLRSMSPPESPFRRGSSSAAGGPPVSLGMRRTLRSNSESSQDSKRSSIPFPSFGRSSKAGKKLKQPSRLRDDSSDDDSPRAPAFRSRFADSSDEEDIEPLPPTRPMSKGTLRDSATAPSRIQRSSTVVEETEETPNLPDSGDDHSMQMPSPLRSPKSAALFRPMPQHRSSSGIGTSTLNRSGLGRARLNEPVYTATETPKNRRSFMGNILRRNKKADPAGKIQRGGLTESAARRDTLLERDADELRGLRGDGVLENPKLQKRRPGSSDDSWPLPAMGENGRPSTADGRVNGGPMARPNISERRSTSMGLPGVAQPTGYDSKDVLEPDNHNKKKKKFGALRRMFRLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX71</accession>
    <name>A0ABR1VX71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010518</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666795.1">
        <property type="nucleotide sequence ID" value="XM_066814833.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047893"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF9">
        <property type="entry name" value="NACHT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G01760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="340"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2024"/>
            <end position="2046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2133" mass="242810" checksum="6A960E91F388A22B" modified="2025-10-08" version="1">MEESKSKISATSMLGLRKLPLGLGKRRSRSRTSSISSKQSTEELSSDPAMAAVRQSNDSSPVRSERQPQQQHYHVETRTTSDEQRTVTIKHTLTVRVYEEALKVRKRIIREVYDVDDGHFDYVNLESYLTFISDERLFHMPKKGSRWDRVLQEAEFFGLLIDEFSSTVGDLVSESSFVRDTALGGCQMLLELGCDQAEALEPTFNVLYEFGHLLGHLIHLRDLFTGNETITQSMSNLYASLVQLIGDIAVTYRQRISRLSSRNNTVSIDFDKEFSHQIRDVWTLRSRLFEHMWSRALRNEQDVTSELTALQRKLAPSTSSEERSQLLYGRITEKAERAEGTCEWVEDDLVDFLESGENLLAITGSPGCGKSVLSAWLRERLQRPIHVGRDRTKFETFGFAFASDNPEESTTLAFLKSMASQLLAINVGDARLLQRLMRSLDEWDSKRDAGKLETDLWAAIEMGLAAISGRDVPTVIIVDALDEVTDGDAKASILSEKLRVIASKLSLVRAITLSRSATQPAKPGVRHFSITPDHLREDIRAYLHACLSTSIIVSKQTRDKQQAFMSLMESRANGSFLYVYLISKLLAAGADFDTLNKSLSSNTFNPLKELFAKVNFKDSGISRLFTFVIAAQRPLTVGEMEDILSVDLTERKKVTSVELAKLVSQTAGLIVIRDGILRFKHASIRSHVLKQQCGQALPSLNDCHRQLTMTLLLFARIHLSRPHDPCLDGADSTLVHQVFRTHHIMEYLVYRWMSHFRRSSLVGKADELSLPSGFKEIFPESTLLCLLEWSTWQEDSTDTIQRHDWALRIRSTCLGEKHPSVLQGLIVLGHLYRSRSDAHKASECFYKACTVGQVILFKFSPIVVSCTTLFLACSDHITFTSRTTICTYREEMVRFMIEVCKGQHGAHSDAVIRWYKVLAQLYVDIKEEYMAAIIYKELQEIIVIRCGRDSKEAWAVRKSLAGLNIVLKKDDGPRSIGQVEETFFESVEDLESTDEMRITILLRLAITYEAECKLLLAERLYLSLWQSISHACRHKATLELRLCHIDIAVKYVRFLERQQRVDEARNILLCLWTEYEHQHFESQTIIARLKELALVFKAFGLLTISVSILKRVWWWFKENKKADDEEAVSTTVILTEVVEEITETITETTVHTTVTETISREIFETVYTRCKSGHVDRHFYKACLSLASIYIKLGKWAEAETIIQRSLELVWKAVLTMHTRIPIEEEFVTERITMAIRLATCYQHQRYLEKADQIYVHIYRACLISLKADHTSVTEAVAVLIAFYQEYHQHEKVIGIYKELLLHYRQHLGASHKLTVRLLYKLAAECMKLGRKEAYEYYIEIVTLYIGKDGSCHPDGFEAAIIVVEYYYRESRWKELQQLCGVLWETVTRHQHSFTEVFIETVYTRYRYVLEVHAKCDFAALYRLTVQYRDVVRKCFDATAVILVTAMLALAELCERHEEHYHESITIYEEIITKTKTVTTVTETKVRTIKKRLSTLYVTVVTSGKKTDGAIIERGCVVCRETYEQLQVELGWWHETTLLALRELVLIYSKRSNSREIITELLQASIVKIISTVQTSKILYDAAILLASIYVAVGMQQQGQELLRQLRLLLLFPDFAAEEPAMCGQRALSLKFEAKSTKVTLIFLLAFDEGLAVHHNKDSVCGFSHLMAELLMESLLYEQYTSVVCNFSESTNIEVVLEHAARLRYVWLARGRTSLVNLLDKKVFTLFMARYGQHLGDTKENAAFTLYVALLSEIGTATTSDRTTIDFALLTCRAVTAAVRAKLVEENDYADAHAVAGCGFRFAETQRFYHRRRECLVYGYRLAELLAGHGVPNWKSADAGLNKKTQGASKIVLQVVMAAMKESGVEPVNLRFDDLSSLIHLLYEQENYEELERVLLSLWHSREVQRTWSTDIVLRIGSLLVEAHARVPGHLDRALELCGTMYYNVRQSRGGSSAKALDLGRRLTSLLQYAGRAREAGRVHERVLHDLDEMSGGYDDAGCGQRALEVRRERMRAAAETHLEGMRMCGWGGSGNGSSSPTTPTSRRRSTAELYQRLAERYGKLGVPPVDKWEGKSVVENGSKGHVEFGSVSWVLHVTDDEKRDDGESAGLKRDSIGLAKQRWGCWGKSPEVQLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX72</accession>
    <name>A0ABR1VX72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosome biogenesis protein Sqt1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009096</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665373.1">
        <property type="nucleotide sequence ID" value="XM_066813411.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046471"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="131"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="363"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="52062" checksum="2D93B64E5BDA0FFA" modified="2025-10-08" version="1">MSAPPPRDDEMDDSPELLDADEALEEIDDVEGDVAMDSDDGEEPEEIQMVNDSVAYFDAHKDSVFTIAQHPTLPSLIATGGSDGDGDDAPGMGYVFDTSGVSGRPVLPSQLCDRPQLRYAKEHRTHPLFALEGHTDSINAVAFTLPRGEFLVSAGLDGRLRAYQLAIDGHNKAKLNFVGEAQEVPEINWVAPCPYAATPNTIALGGSDGSVWVYTIDASDKSNPLQIVQTYFMHTAACTAGAWSPDGLLLATVSEDSSLCVWDVWGEAAAKGLTNDNGQTVVSLNGEDQRFEVEGGLYSVAIDPKSTLVAVGGAGGAIKIVGLPRLNNETAPQAQPQSSRQSKAKAKGGDAGSAQSGMILASLHTQGDGIETLSFSPTQSLLAAGSVDGSIAVYDTAKSFAVRRHLREAHEEFSVVKVDFVKGDGWILTSCGMDGVVRRWDLRITGQNTSGLVKEWRGHRGDGEGGGVLGFVQGTGDRIVTAGDDGIVLVFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY09</accession>
    <name>A0ABR1VY09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665673.1">
        <property type="nucleotide sequence ID" value="XM_066813711.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046771"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="255" mass="28458" checksum="9AB1CE779341EE5B" modified="2025-10-08" version="1">MLFTTALRNVQLRPMGLRLCRASIAPRFVSPRSPSQILCRRLASTTPTKPVANGLKAAPERKYMYPERLCIYHAGTGRVTFLACLKLSTIFVFAFFGFVVTPTYIEKTGWGDTTLRTGSTAMAAAVGPLLIVGYLTSPFVSFMHLRLPPFARVSEEALRSFVKRLPAQAQTTELDITTMSAIAKPRVSKVKLSELRPANQRLGIVNYVRDTTAENATRKWYNFRAVGKFNVQHNMSPRVRGIWEEIAAMITKQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7S4</accession>
    <name>A0ABR1W7S4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667007.1">
        <property type="nucleotide sequence ID" value="XM_066811665.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044725"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="178" mass="18250" checksum="A13F7E01753AAE28" modified="2025-10-08" version="1">MSSLPVFATPTAVPYGFTVQVATCTKCGAQPLTVAITFPSGGSPFVPAATTMANGGPLPTPTSTPGAIITPAVTNASSYSSYSTRPTGAPQNSTLLAFNTTITANITLNVVPTPGHSYSLSTLFTSYGSAQEPPATLIPSIYSDQASSGYIPMTFIRILMALKATVVVDTTFGVFVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9J4</accession>
    <name>A0ABR1W9J4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667622.1">
        <property type="nucleotide sequence ID" value="XM_066812280.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045340"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="31"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="901"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="472"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="940"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="986" mass="108370" checksum="6952FE34A86C569C" modified="2025-10-08" version="1">MDVEAAPGASDKAPAAGEAALASSTQQPAQVSRLASLPEELQKEIFSNCSQCDLICLSLVCKSFRELAAAQLYRNFHIVFPDEDDPSFDSPIDGLAGGLDTFVTSEYNYAQHLRDISLDTLSAGDKAENAYKPYLFGVSCGKFMNSLLLLTLRKATSLDSFRWNIRVELSRPVYKALHNISSLKHVHLRMQSGGSLYEPPPPLPYYSSLSTTMPMPTAAHIPPLPVVPSIEIAGGATLTSIFGGPGTVTWGPPPPAPVPAASHAPAAKHSLKTKPPKKQTSTEKDPSTIGGFRNLESLAVLDIDCLDIATEIRNCIGNSSSTLKKLKLSFSDALATQARKPCLVDPNESDEDDDFQVVPVSSGYDDGSGPAKAFRAQEERKIQESVLGRIFDIEPFVPRKSPTSKEKKTEAKLTTQDASHRFISSMANVAKRLMLGVDGSRTLTPQRQETLELMVEAAKKYVAFKEDLTSEGAAADGAGPSSSGPNGYMADSENDDAETVAEGALSSVMPKVQNDEDETRPEDIDVAAPEEQLVEQQEDVNSDVVSKAEATHMDISTVEPAAFHPSDSTPALEDLRPAVTGTPLVCLGQSPGAAQNSQLLQVHNAPDSDEKLSNASLQAAAEKLKGLEISDKEHDMNILEAELEDAGDSHDAHTVDDKEELRRQISAYIRGTRGIALQSLSLHLIPTKASVLGRAIDLHTLRKLTLLNVGNQAPIWALLAKENKLAPLPLVKIFTDHVSLPFLHFVSQLEQVQELFMLERSVKYKPESFAPKTKITLEQIRRFALKRHMHTIKRLMIRNDADDTWDADERTTQLICRKGKDLEELAAIMGIKSVHTFLQHLAGLTNLRALHVISFRSDDTCLSVMRETRRFIVDTISHFPELKLEWLSIGDDDRAERIMRRTDLPNAKKKKKKGKGKDVSPNVPANADVEDDYPAFPDDRWDEESDSDEDDGNPQRWQKLDIIENIAFYDVWGVKIFKKEIMAARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9V1</accession>
    <name>A0ABR1W9V1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_008061</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions as a zinc transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667718.1">
        <property type="nucleotide sequence ID" value="XM_066812376.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045436"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045316">
        <property type="entry name" value="Msc2-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755:SF4">
        <property type="entry name" value="ZINC TRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="434"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="277"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="82"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="171"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="404"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU369017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8080243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="609" mass="67161" checksum="4D0954871BAFCCB6" modified="2025-10-08" version="1">MKCQLIQARGRTDLKSTTFLCCAVLHRQVATTDTRPQPSIKLLRRSGTIDRLRLRDSQLPITPWHRHMPFPRLLCPLNHAHHGHEHVQSHSHSRSPPTFGHSRRSDRGSSASMHSYSQSLESLNAYANGHGHGHGHGHSRSQSHDQYHSEGDDHAHAAAHTQNTTQYKANSFLPMQRRENRPSPLSRKTSGNAMGGNTLSPVQDASPATPGLNGSAYFDRTPAGHHHDHDHDHGHDHGHDHDHGHDHGHNHGHNHVHAHAHDHGHVHAAHHSKFTGFVNFSFMAVQAFYGYVTDSLGLLSDSIHMFFDCVALAVGLFAAVMSKWAPSERFPYGFGKIETLSGFANGIFLILISVEIMFEGVERLMEGRETKRLLDLFVVSTLGLIVNLLGIFAFGSHAHHGHDHGHDHGHGHDHGHSHGHSHGHSHDNENMHGIYLHILADTLGSASVIFSTILTYFIPWSGWDPVASFLIAYLIGMTAVPLVKSSAHKLLLTNPDDTEYNLRNTLSGITGVRGVASYAVPKIWEDDRTGSVGESRTKLIGVIHVAAVRGADMEDVRERVGNYLLENGIDSTVQMEREGDTACWCGMGRLELAGAHEPGVQKIEETRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAF3</accession>
    <name>A0ABR1WAF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitochondrial protein import protein MAS5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007263</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666920.1">
        <property type="nucleotide sequence ID" value="XM_066811578.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044638"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF10">
        <property type="entry name" value="MRJ, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="13"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="459" mass="48496" checksum="614C5D02A4CE8C3A" modified="2025-10-08" version="1">MTETFGQKPSLAECYRTLGLSPGADEAEVKAAFRKLSLKHHPDRAGGTPANNAKFAEIRNAFEDISDYLAEPKQERWAEPPGGFPPGAGRGGFPGGAGSSYGGYGGYGGGGYPGAPPPGYGGGRGRPEGRSYFPMDDPDFGEFFDAASEFMFGEKGRFPGMGSSSSRGPPPSRGFPSGGFPPGMGGFPPGYGRSSSSGMPPRGYGDFPSSGGGYPRGGGGGGGGRYGDFDPFSGRGGSSSSRGPGRDQYSSGYGKGGSDEGEPAPPREDKLAVIQWSLRRAHRRLAPLPGKLFNMRRWWDKVDECGDLSPKQRVLGRERFDRAELHLAKMLSQATEQMESVRNHQDKKEKKKKSSSSNRYSKMSGKSEGKGKGKKKQLDKWAMPAMQLGRDSEAVLNEVIALEQCAKHDDLNEFLAALSDIKSGGGSGKKQGQEDGSSEEDESSSGEESSDAGSGSESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBC2</accession>
    <name>A0ABR1WBC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nonribosomal peptide synthase SidD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008619</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668276.1">
        <property type="nucleotide sequence ID" value="XM_066812934.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045994"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19542">
        <property type="entry name" value="CT_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="171"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="709" mass="79328" checksum="E727FBCE2462A568" modified="2025-10-08" version="1">MLVCSLDPKGFLIMASFDSQTVQSEQMQRMLAQLGRLVQQFCETPGKRIAEIHVNDDGELDELRRLSQAGVESLRQLSPFSDIQASEVWLADPMSPDRLVPLGATGELILSSAEATLPFDAIELPSWISTKADQTYYRTQKLAKFKPDGLLQLVERTAATANQMQASSAVSASSAKQRKLIKAWSRILGVQEEEISLEDSFFLLGGDSIGAMKLVAEARTEGFELTVANVFKYRTLYDMAGAMRENKKANANNSNQEQQIKPLSLLKKDDPSKFIAESIQPLLANPEWVVKDVYPTRPLQHVAVNGTVKLPRYSARYELLHMEGGIDKNRLMESCQELIKRNEILRTVFVEAEGQCHGVVLESMTSEIEHYDVDSATDMASFTKELCDRDIQNEMPHGSAFVKFMIVQQQSSTCLIVRISHSQYDEICLVSLLRQLNAIYDRRATNDTVPFSAFVYHAVEKAIPESIPYWKDLLRGSKGLSVLRPDIPLTGAGIPDAVTRTVSIAARQRDITVATLPTAAWALCLARRLGVRDVVFGEVVSGRHVDLPGAGGADAVMGPTWQYVPMRVQFDPASSWTGLDLLRYVQHQHIAGASHEGMGLREIVPLCTDWPTDPTSDKVDEYWFDSVVHQDVYHVETMSMGGVPCRLETVYPHYEPLREWKIQAFVQGDELMFEVVTFKEWIGVAEELLDELEGIMEVLVKRPQEAIFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBJ0</accession>
    <name>A0ABR1WBJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein ARV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_007699</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Regulates also the sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Golgi apparatus membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ARV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667356.1">
        <property type="nucleotide sequence ID" value="XM_066812014.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045074"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007290">
        <property type="entry name" value="Arv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467">
        <property type="entry name" value="ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467:SF0">
        <property type="entry name" value="PROTEIN ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04161">
        <property type="entry name" value="Arv1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8079881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="292" mass="32035" checksum="85A7532C63BD2DC7" modified="2025-10-08" version="1">MPICIECRHPVKTLWTQYSGAGDPSSGHNIRLTVCKNCGRFCDKYVEHDFVVLFIDLVLIKPQVYRHLLHNTLMREGDQFDPSIVRLGTLLLLFDVYLTWARIEKQTVPGAEGSTGEERATSCSTRLLGVTLVRSRSSPLSSIILCTCSTLAFQLSIRFLTSSPLSPLNQLGMLRTYTRPNSVSTALLVSSSTKLFPILMVIWDYDVPAAARSLGWAVVLNNVEALKILLDCGYPVALVLAAAGAVARWIVGRAILWVVGLEGVDSVSESAVAADGRAIMEVVKEWAGRLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCV9</accession>
    <name>A0ABR1WCV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668317.1">
        <property type="nucleotide sequence ID" value="XM_066812975.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046035"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046931987" evidence="2">
        <location>
            <begin position="24"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="128" mass="12864" checksum="0FA1C4586D3F2FB4" modified="2025-10-08" version="1">MHLTHHLSWALAVLAVCPSAVVCVPDAMGPTATTAPASSITQKESGDAPVTSEGSSSSASPHSSSPTDSAESNNSTMATTTTSEAPRPITTEVVVTPTTSVPNLLSGASGKDVELITSLLGFIVAFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WG55</accession>
    <name>A0ABR1WG55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008972</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668629.1">
        <property type="nucleotide sequence ID" value="XM_066813287.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046347"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF238">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="13"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8081154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="447" mass="47919" checksum="1AADEAA106640461" modified="2025-10-08" version="1">MASFDGNSDSPLHVLVVGGGLSGLATAISVSLAGHRATVFEAAPQPHPFGSGVVTCPNGTRLLSRWGIDEDVPDTGNHTSIAGWQLCDPLGTPLRQVLIAGDGGDDAKAHQGSLPPWTFHRVNLQLALLRRAQELGATVRFGARVTGLDDEDDDAGVTIQLESGETHQGDLVVIAEGTNSRLRNVILDQPVDPVATGYVAYRITVDRSMVHDPALVTFMNAAGIRTWVGKGSYVSAFPMRRGAQLSMMVLIPHGQLPHGATAAPEQELKDYFKKWDTLLPSMIDAAQRVNKWAAMHLLPEHCSPQGTCILVGDAANTMSPFLNQGLSLDLEDAATIGCLLGHVHSTSQLPAATALYARLRNAQAKRVREETAIFEKQLRDMAGGCINDEESSAPGARSCSKLEYAQATSVHTTSTDFGDRTGRLAPEWMWSYDAYAEAEAAFKSDPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMA3</accession>
    <name>A0ABR1WMA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytoskeletal signaling protein slm1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005929</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669167.1">
        <property type="nucleotide sequence ID" value="XM_066810244.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043304"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046868">
        <property type="entry name" value="BAR_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046869">
        <property type="entry name" value="SLM1/RGC1-like_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941">
        <property type="entry name" value="CYTOSKELETAL SIGNALING PROTEIN SLM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941:SF1">
        <property type="entry name" value="CYTOSKELETAL SIGNALING PROTEIN SLM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20400">
        <property type="entry name" value="BAR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20399">
        <property type="entry name" value="PH_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="301"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="481" mass="52329" checksum="0D0759E3AD344E90" modified="2025-10-08" version="1">MSADSQPMPLRQGTTMSSSFGDEAVPEFDPASTAGLLSERLRAWKHAIAYLEEYVSATEKVHKSHAKEYEKVLKTISQPLREGRHFDQGLGGVAGFFENMRVNTQAMINSNAETEKTLKGTVLPILERLHKEVKVKTKEIMSGAEKSSKEVEKARNTTQKHIELLGQHSASFESAGGKMNPADDPYVLQRGVLHRLNKQVMEENNHRNDLITVQNHFQAFEAHVIQVVQQAMEAFNSVAGGQAEKTRALYADMLSTAQRIPPDFEWKGFQHREAHQLVDPNEPPRSVDALTFPNQGHNSTKALIEGSLERKSRNKLSWGTQTSYYVVTPSKFLHEFKDDDNFRADPKPELSIYLPDAVIGTPNGDKFNVKGKDKSSSFSSKLAGASELSFKAHTPADAQKWYEAIRAAAGTSGAGAMESTPASPVVGGTASSTGAFPAEKAHAPEKGQEAGITGNDTVSSPTAMSPVEPATAATGDKKSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMK0</accession>
    <name>A0ABR1WMK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AHC1-like C2H2 zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669269.1">
        <property type="nucleotide sequence ID" value="XM_066810346.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043406"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058706">
        <property type="entry name" value="zf-C2H2_AHC1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25909">
        <property type="entry name" value="zf-C2H2_AHC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AHC1-like C2H2 zinc-finger" evidence="2">
        <location>
            <begin position="291"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="686" mass="74238" checksum="5B10A6B5F50E6616" modified="2025-10-08" version="1">MLMFRFWGSDSRGSDKPEQVLHQPMLDFAKPVQSLVSEPCKVTSPSRPPKRRRQSNAAIASHPAAAALAVKRLRVDEDDQDESRPKKKVALAAQGAEDEAVRSQAPPTPQSQTLSQSRRGSAELEHAKEIIQHQFSHDILLKHNELRLIQQELAKCQVALEQLRRCHLIPYPVNTPTPDQMLQISSGMGPALKAKAGDKVPQWAPPFGVTDGPYARHYAKWLIPDPKFDGIVPESSVHAESTRFRNGVESRSMRNSFGEVGVMPTKGRPPRGSAGQKLHALSNGYPQPKDKAGPCVLKRSDGKTVKLVCLDCNRENFSSTQGFINHCRIAHKRDFKSHEEAAVACGHPIEVEEARGDAQEEKPAAVSVSNTNSAAAVSATPAVATGLVHPFARQNGLAESEPYFSVLARIKESMDMFKKGQLPNVKSIPGVPSTPVSAKPSNHAPAKFAASADSPHLSRLLQSRGKSMDLSELVRDAKTKINLDEVMSPEDEDSEEVEPPSLLPNDGDQGAVMRMPRIPARTTKSPIPMPSTTRPVSSKGRPPVGVPVGAYATPVPTPAARAAPEQEPDLPRIDDEMELELSPNTAISNNAPSLVSDDGEYDDSVDGSSDESVANDSLDAESMSDVAEIGFDDDHVGPRGIRHHRGSTAGHTAVRLRKEDNKHVTIVSPVKNDGGPKKRGRPVKGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMK4</accession>
    <name>A0ABR1WMK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006036</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669274.1">
        <property type="nucleotide sequence ID" value="XM_066810351.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043411"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005012">
        <property type="entry name" value="PRK06411.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56770">
        <property type="entry name" value="HydA/Nqo6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase-like 20kDa subunit" evidence="3">
        <location>
            <begin position="104"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="229" mass="25446" checksum="5C141F357F30B54B" modified="2025-10-08" version="1">MLASSRRAASLALRAKPATHLLPLRSVAAFSTSNNQNAAAVTAHGSTGLVNKERREVPLPSQGGHQGRHSICAVRINPFKTTLDQVANWARQSSLWPMTFGLACCAVEMMHLSTPRYDQDRLGIIFRASPRQSDVMIVAGTLTNKMAPALRQVYDQMPEPRWVVSMGSCANGGGYYHYSYSVVRGCDRVVPVDVYVPGCPPTSEALMYGIFQLQRKMRQTKITRMWYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN20</accession>
    <name>A0ABR1WN20_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668921.1">
        <property type="nucleotide sequence ID" value="XM_066809998.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043058"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="249" mass="27603" checksum="343FF6B27714E92E" modified="2025-10-08" version="1">MEHHDTTAHTVDELRDTALSTRMQPTIESPDRTVSVFICHWDSDAENYAEIDSGIHALRKTFEHQYGFSTEVHELEQAKSGSKNQLTLMSRFLPLLYDTSPDPMMPCRCLDGMHRYLHKPEEVNLFIFIYLGFAETASDGSCLLRPVGQPDQDPASLPSVKYSSISRATIDMGESQVLALLDCPYDGPSTSAMSANKGTHRRRLRPVDARVRVHHAPGPPHPTRRAGPAGTEHAAPLLPTGQHALLASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNH0</accession>
    <name>A0ABR1WNH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dihydroorotase</fullName>
            <ecNumber evidence="3">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006254</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669492.1">
        <property type="nucleotide sequence ID" value="XM_066810569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043629"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01294">
        <property type="entry name" value="DHOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00856">
        <property type="entry name" value="pyrC_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137:SF1">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="8">
        <location>
            <begin position="85"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="351" mass="38423" checksum="58626E4D03F83581" modified="2025-10-08" version="1">MKDSYILPAAADMHVHLRDGDMLKAVVPTIRNGGVDTVYVMPNLVPPVTTIAAALEYKKRLQDVDSSINYLMTLYLHETITPDVVREAKKAGIAGIKSYPAGVTTNSSSGVVSYEPFYPVFEAMQEVGLVLNLHGEVPSDKKDVTILNAESKFLPTLKDLHRRFPKLKIVLEHTTTADAVEAVRSCGETVVATITAHHLSLLVDDWAGNVYCFCKPVAKTPEDRKKLLDALVNSNGKFFLGTDSAPHDISAKKGKGNAAAGVFTQPFACQYVLSSLEEAIERGDVKDEQVTEGLLRGFLSDWGREFYGVEKATKNILVKKGNATIPESIKDAGVEVVPFRKGETTWSVEWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNU6</accession>
    <name>A0ABR1WNU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006359</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669597.1">
        <property type="nucleotide sequence ID" value="XM_066810674.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043734"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="309" mass="33560" checksum="EAA5E6254559603F" modified="2025-10-08" version="1">MKFDFDKDVPDLTGKIILVTGGNVGLGKETIYQLAKHRPAHIYLAARSAAKAQEAIKDIQQRAPDAAPITFLECDLSSFDSIKSAAANFLSQSSELHILINNAGIMACPPGKTKEGYEIQFGTNHMGHAQLTKLLLPTLLKTAEKAPEGAVRIVSLSSMGEAFAAKDPYADADTRLKSDLASLSTWTRYGIAKLANVHHSRALAQRYPSLRCVAVHPGAVRTELTRGPLATYSAFSLIMTPLHWLATFAMTPVSEGAKNQVWAAVSPDAQSGHFYYPVAVDGKASAQAKDDKLCEQLWAWMEKELEAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ69</accession>
    <name>A0ABR1WQ69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_006839</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670077.1">
        <property type="nucleotide sequence ID" value="XM_066811154.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044214"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF8">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="536"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="536"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="653"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8085568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="664" mass="74163" checksum="A759A0A6AF534E7E" modified="2025-10-08" version="1">MDASDVFRHIEGLGTYQPRFPQGYHPPGRPAIAIRDEHRKTRCDPTLPRCLPCERSGSVCEYFDTTKGKKISRYYVVKLQARVRALEAELGQYTDEDSFPQNNDDIVAMTRILMEEAKRYTDSQHISQLIPGVRGRRQAAVGGPGHTGLRSQSFSIPPPMMSRKKSYPMISSFPADTLPSRAIADKLVEVYCQRGQILTPTLHENRLASDLDDVYNGSQDAYQHFVIRMVMAISMQKLDTTYAGLADSYYLAAMQRFEEVLGLADEKTIAMGTEDPLTLDMRRRLSWTITAFEFGLASSMGRPNGFAKSDDLVDVKFFESAKDENITEHGILQGPADEKKLIAIHFCKMRLCQSEIKRVLYEKKQPEPRDERHPWFAAMETKLDQWLDASPASPAWCKPWFTGKYHTMVISLHRPSPQVPKPSSRSAVKCFDSAAFIIDLSSKQMMAAAVDITWVFVFTLYMALNTILWSVAAYPDVRGAHSRDEVEELVNVALDILDQCAERWPGISAASELYSTFSKACLRSYEARHTPVLSASSTFGTPSSQQDMNSPSASDNSSATTVSRQGPTNGVPAFNPPQFGYVFDTAPEQVSFDNPFAGQPTFRSNSIFHNPAPSDPSGRRFSYFPPEFTQSNENLLLEESTPPESDTNASPPLLSPPNHLPTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQR6</accession>
    <name>A0ABR1WQR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670370.1">
        <property type="nucleotide sequence ID" value="XM_066811447.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044507"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="73" mass="8139" checksum="0656B366BA3E029C" modified="2025-10-08" version="1">MASCPAIDFIPSPTATMANTYYCCNCDADQEFFYGQCNACRKLCQQLLLDWMRSSLNILQAGTYKRADPADGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQZ3</accession>
    <name>A0ABR1WQZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669399.1">
        <property type="nucleotide sequence ID" value="XM_066810476.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043536"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="330" mass="37178" checksum="2C8A1CE726E95835" modified="2025-10-08" version="1">MAERLPPVEKLPLALRKNVRDEWDNKKPEIEKELSDILTVPWTVEVNPNQVFAYAGDGYAKESLGSCIAAAVLLTLMCVTLPKSYFKGAIWQFKNYESSYGEEGLKELNDICHAHVLTMDVDLNKRFTYGGVDVDERGALRMLFAPDNLGCNIDYCVERDTLLKALNNAPAAPGASGSAISFATRTGIRQDYDPKIEAIRAKIAELLAWPEIQLNPNWEEVFAALKAESQVKKTELREDWQAYMGSMAISYFEGLLSQIQWQKFEDDDLLQEGFRDAVSKGEVKFRIVEKLKDSSYSECQVEDGILYLQSTAKTWGTNTSYTAEKLVDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRZ4</accession>
    <name>A0ABR1WRZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-thioesterase ii</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006971</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670209.1">
        <property type="nucleotide sequence ID" value="XM_066811286.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044346"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03444">
        <property type="entry name" value="Thioesterase_II_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03445">
        <property type="entry name" value="Thioesterase_II_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049450">
        <property type="entry name" value="ACOT8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066:SF35">
        <property type="entry name" value="ACYL-COA THIOESTERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20789">
        <property type="entry name" value="4HBT_3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="3">
        <location>
            <begin position="34"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase-like C-terminal" evidence="4">
        <location>
            <begin position="148"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="281" mass="30232" checksum="5E2A512A334D43E9" modified="2025-10-08" version="1">MASAATIERRVGVQHPPYVGPNTYANEEPLTSQPTGRAVFGGLLLSQAISAASATVPSDFHVYSSHSHFLRPVAATFKDRVLYHVDRIADGRSYATRVVRATQGDRSACVYIATIAFQNSNSAGAGNVWTTPTDVPADLNRKILADGSSPDSPLQPLSSEVEAFARAAEPLTSTSSAMHMAALAYMSDEMFLAMAIVANPNRVGVRARNVAMGATLSHRIAFHEPAVARVDAWMVSERETSWGGGGRVLLHQRTWDLGTGRLVMTCEQEALIRLKGDEPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS26</accession>
    <name>A0ABR1WS26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipocalin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670329.1">
        <property type="nucleotide sequence ID" value="XM_066811406.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044466"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20684" checksum="A3411C65543BEB2D" modified="2025-10-08" version="1">MVNLVAAKKAASCFVGAWGFINSTLNTTSGDIITEDWAYPVPSGASLFTPNGYAALLVTANDTTKPDLRPRFLTQNDYASGNDTEWAKIGKYSIAGVGPYHLSNVTWPGYDCGDKGKKAEVKMDEEFEGPEGIQTGSFFSSTLPSREGPYEFAFKFYESCHVWNLHQPVGGGLERVAWYEKLPDQQVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS29</accession>
    <name>A0ABR1WS29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669968.1">
        <property type="nucleotide sequence ID" value="XM_066811045.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044105"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="291" mass="32127" checksum="7AFF78AC54E7B904" modified="2025-10-08" version="1">METGTVNLWSGNLKNVMALASGNSIYILSHFVTDPAVETPSSAIVRIVGNVGKAGISLLIPPASEPLIRPLSNSLRAVEYASFDGRRENNFTSTSLHLSFTPHEFPLDYGTSDIIDHQVFFVESVVSVHDSGKWIADLNILGVFRNGARQILRLPSENQSKQTHGHPDEKQKAALEAFVSIDTWEEVLDDPSTHALVRASGSWAARLAAATNAARGPKFAEEDDDNDMDNERTGEKEEDQNQQSDNLNHHRRDRVHVAIVEKGESVCWVCVHTRLSKMGWLAFQAPCYIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWY7</accession>
    <name>A0ABR1WWY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670576.1">
        <property type="nucleotide sequence ID" value="XM_066806958.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040018"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="54"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="558" mass="62413" checksum="1C0300843E4679DF" modified="2025-10-08" version="1">MTLAASRNSPTTSSSTATTTPQDNSKQQQQPHPQQEHKQLSDDGAQRPEPADMAPSLLSLPLELLLHVSSYLDTPECGSLRLSCKQVENALYLTFARDNFTKRQHMLTESSLQALLDISKSRLAPFVKTLFIGTDLYSSDGLKHITHLHAHPNLHRGSAGAVRRSKFVAQSSSQEALLNSGYDMELLTAALGNLTLDLIGVCDSYYSVRFPGNPVLSPSYGATAIYCDTCIPSRHKSGIEHAHFSSKCANKLLFAAARAKIAPKRLQFRFSQDGLIDFAFNIPKFLEKDVARLLSGLEELKLDLYGNIAVDTTRRAILHEDDPSEEIYTYHLRRFLALTPNIRHLRLNSPVSDDHHDHFLEWLATAPPTSPPQYTCTLTVTDDELLAIVTKFKRTLKNLSLQKVLLVDDTDEVYNRQNPPPNKWASFLEKLCRSGVRLDSIYIKGAEQQNTGVIVATVSFTSNKLNVAKHQGPDTMKAVRKFADDAELHFVLPLAEEGEEHPAFFDEEDDDEDFLDYDGDEGMEFYGLDPFDEFDDEMDDLFLAGHLTMGGPYDHLMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXC6</accession>
    <name>A0ABR1WXC6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular glycosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670713.1">
        <property type="nucleotide sequence ID" value="XM_066807095.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040155"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02183">
        <property type="entry name" value="GH16_fungal_CRH1_transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF68">
        <property type="entry name" value="GLYCOSIDASE CRH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="1">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="305" mass="32228" checksum="832AE8B236A9A328" modified="2025-10-08" version="1">MPLCPSGGAPTYDSEGAKFTVAKSGDAPQLSSIFYIMFGRVEFYMKAAPGAGIVSSMVLQSDDLDEIDMEWLGSDDYEVQTNYFGKGITGSYNRGQFNPAKNNQAEFIKYVVDWDPNRIVWTVGSTVVREMKYDEAEAGQYPQSPMQIKFGAWAGGDPSNPEGTIGWARGPTDYTKGPFSMYIRSISVTDYSTGKSYKYGDTSGKWETIQAEGGKVYGNQGGAGALTTNAVAASPTGGSPTVPAGGIGKGTSTPAYTGSYDVPEGWRMTPSGKVVPSSSATVSPNFALVIAGAFSVATLAFSSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXG9</accession>
    <name>A0ABR1WXG9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">P450 monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002801</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670734.1">
        <property type="nucleotide sequence ID" value="XM_066807116.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040176"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8087840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="540" mass="60326" checksum="406FC376668D4F36" modified="2025-10-08" version="1">MLGHIEDLPRIAVLSLEILAVAIPLIIFANLVRRLFSRASLPPSLPWVGTGPHSGPLSRAQANLKSFFGLKTLLDEGYYKYSRNNQAYVLPYFLNGYQVVLPLSQIDWLLAQPDSALSQEDVNRQFLESDYTFPHPSFVKDPVHPEIIRHELTKKLNSFADDVVDEMEQALADSWGTNTDEWVEVNVYQTLLRIVARLSTRVFVGLPLCREPEFLEVCESFNRNVALSGAFLNLLPSFLKPFLAPLVSSADYLRYKKCSRYILPTIKERLGILKNREKLPMFDPSPPSDYIQWAIDHAVQKGGLESRELESRVIATRFAILCFAAIQSSVITLTNAVFDIASSPDCVSFLDTMRREVLNETASATTAAPSWSRAMMARLTHVDSALRESLRLNGFIERGIMKMVVAPGGVTLPGGSHIPRGTKVGISGWSVHHDNDIYSKATTYDAFRFAKGSASGKSDGNVNNKPQALINTSDHFMGFSHGSHACPGRFFAANQMKIALGHIALRYEIEPIPERPKNQWFFGHIAPPLGNTLRVRRRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXN7</accession>
    <name>A0ABR1WXN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_002862</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670795.1">
        <property type="nucleotide sequence ID" value="XM_066807177.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040237"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045398027" description="CFEM domain-containing protein" evidence="11">
        <location>
            <begin position="20"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="12">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="108"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="144"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="236"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="299"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8087901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="345" mass="40693" checksum="BE99DEDD70A3D341" modified="2025-10-08" version="1">MHFNAAFIALLAAAAGVSASTLEDRNLGPPQCAELCFKQAIASSQCRNQKNYIRTLWLKKANWECLCQDQQFHGSVVPCIEQQCKKPKDLQLVNVFLGKTCGYSVQSSGGYQQPAQQSQPYEQPSSKSQYKARNYDNPQPYQAPKDEYKQPKEYRPKQPEHYEQPAKSEYKPVEQPKQEYKPVKKPETYQAPKAEYKPEAPKEQYQPKKQESYQAPKNEYKPEAPKKQEGYQPKQGEYKPKEKEQYQAPKNEYKPEAPKKQEEYQPKKQEQYQPKKQENNVHNQEYKPKKQEQYQAPKNEYKPEAPKKQEEYQPKKQETYQPKKQEEYQPKKQDQYQQQAPKKNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYI3</accession>
    <name>A0ABR1WYI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671104.1">
        <property type="nucleotide sequence ID" value="XM_066807486.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040546"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="306" mass="33572" checksum="9BF9D23F97B64A67" modified="2025-10-08" version="1">MEPFSPSENAHHAWHKHRWETTGRWPPETAPQIFVRAFLHGPEDLPVLDHSHIFSATRATRSGLAGNEALLTAVESQPSLHRPQGEEQEEQETLQPAVVASIQTHPLWLHGTKQLRAIVLTQAASVRWKLFGLFLPPSAGGLVRRGSAFPSSQSSQTPSNNHLSGVKSSRDSKGPSRLHYSSRLPYGSLGLHQNPARPNTKGRSPSPPPSLQWSPAPELQLPNLSLVWSESKPKKPSPYYTTKAWGIFPSCRHDTANHVAASRLRLPYSSSRIAAKGRTEACKVYLAPTATGLSHQSAPWSIPPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYL2</accession>
    <name>A0ABR1WYL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671152.1">
        <property type="nucleotide sequence ID" value="XM_066807534.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040594"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="397"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="469" mass="52500" checksum="9EE5563ABB7E97A4" modified="2025-10-08" version="1">MPGPDAPPAAPRERKLPFKRTVKRKSVETPTNNYKSEPDGIDLFRRSGALFDKFQQQESATKAQRRKAKNVDEDAAADSEIQAQLLRDSQSASGKARIDSVDRDLKRQCISLSDDEDEPGSRPSTQRSPRKSSDAPLDRSPSKFRRSTRTATSSTPTSARPTQSSGIRADVIALDSSEDEEDYKPPQSRSKAREAVRDTMDAEETPASQPRSLRAGHSDTESDLDPIEPDGTQSDPLAARFIEEARERMRKERLAREANSAATESPAPMEVVEIYIESHLEGTSNMRVKVHLLQKLGVVKNSWVGYNQKKKMPVTESVLNEMFFTWRGNKLYDFTTLASLDIKRRGDGHLYSSRETKRDGFEGWDKETERLRQLGDLPDDEQETEPVPEPAAKVATIKVILKSKDHGTQNLTVPIDVEVAKLSLAFRTMKKIPEGQEIVLHFDGEILGEESTIDEAGIEDMDSIEVHIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYX1</accession>
    <name>A0ABR1WYX1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L33-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671241.1">
        <property type="nucleotide sequence ID" value="XM_066807623.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040683"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.190">
        <property type="entry name" value="translation elongation factor selb, chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00573">
        <property type="entry name" value="Ribosomal_eL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001780">
        <property type="entry name" value="Ribosomal_eL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018266">
        <property type="entry name" value="Ribosomal_eL33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038661">
        <property type="entry name" value="Ribosomal_eL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10902">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01247">
        <property type="entry name" value="Ribosomal_L35Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01105">
        <property type="entry name" value="RIBOSOMAL_L35AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="109" mass="12217" checksum="196F7538D1F81E66" modified="2025-10-08" version="1">MPTEAGHRLYVKGRHLSYQRNRHTTHPNTSLIKIEGVDDTSAANFYLGKKVAFVYKGQKEIRGTKIRVIWGKVTRPHGNSGVVRAKFAHPLPSKSFGASVRIMLYPSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ92</accession>
    <name>A0ABR1WZ92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MFS multidrug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671323.1">
        <property type="nucleotide sequence ID" value="XM_066807705.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040765"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="103" mass="11787" checksum="905497CD4418F676" modified="2025-10-08" version="1">MSTVRVLLPTGVPPFAIQLVRQVNYGSLESKRYFAPTSASPSEFVEVAEDDLIQANFQKLNSYKNYKCGTHDRFFEVNIYQKDPINKHHWRANLARPASSIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0D1</accession>
    <name>A0ABR1X0D1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WIBG Mago-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671777.1">
        <property type="nucleotide sequence ID" value="XM_066808159.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041219"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039333">
        <property type="entry name" value="PYM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015362">
        <property type="entry name" value="WIBG_mago-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036348">
        <property type="entry name" value="WIBG_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959:SF0">
        <property type="entry name" value="PARTNER OF Y14 AND MAGO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959">
        <property type="entry name" value="PYM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09282">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01273">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101931">
        <property type="entry name" value="Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WIBG Mago-binding" evidence="2">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="203" mass="22189" checksum="8C10141EC0991D4B" modified="2025-10-08" version="1">MPSEPAKASTSGIVTDEVSGVRQIPESIRADGSTRKAIKIKPGYRPPEDVELYKNRTAESFRNRGKGGIPGTEGLKEQKVELPSAASNKNAKRREARKKAKATDDTNDATGDKAKDAAESKPEEVDPEVEKEKKARNLKKKLKQAKELQNKKEGGESLLPEQIAKVIKINELIRELEALGFDADGEAKVKGEDGAEKQQEEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0F4</accession>
    <name>A0ABR1X0F4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">THOC5 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003854</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671787.1">
        <property type="nucleotide sequence ID" value="XM_066808169.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041229"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019163">
        <property type="entry name" value="THO_Thoc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375">
        <property type="entry name" value="FMS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375:SF3">
        <property type="entry name" value="THO COMPLEX SUBUNIT 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09766">
        <property type="entry name" value="FmiP_Thoc5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="185"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="29211" checksum="E64FD7C9E4612F67" modified="2025-10-08" version="1">MSTAEMVTDHNLVSVLDASRDARQQALALVDQIAAIGPLENASAADQAEVSRQQKLLITNLARLRGLHRSAQFRGRHVKQETAGARQEVDRLHLQLQNLYYEQRHLQGEIAACESYESVVTKASTLIHHSSSATSSDNPPPGKVAYALDAPQLAHELIQLQISHTYQQLPLVPIEEFLAAKPEHANDDENALMIARIEHERIERETLEQKRMELLKRKQKLIADNKKRKDDLANLDKELEKFIDAAKPIQKLFEKNISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0S0</accession>
    <name>A0ABR1X0S0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003979</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671912.1">
        <property type="nucleotide sequence ID" value="XM_066808294.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041354"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF15">
        <property type="entry name" value="NICOTINAMIDE RIBOSIDE TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="265" mass="28632" checksum="E64EE55F568AFE3C" modified="2025-10-08" version="1">MLNVFQSFVFYGTQMYFGGMAFVLILNAVFPGFLHMANTLPESAGITTPQLIGFVLFIFLYIPVVYFVPPHQIQRFLVANLLISSATLFGIMGWAVHANGGAGNLASPPVVISKSQVGFMMVHGITSVAGTYTGGSERVSDWTRYAKHRNSPTLAQLTALPVTVTLVALIGIVTTSACAEMLGQVEWNPMMMLQTIQVRYYTASCRAGTFFAGVGLLSVTVFINYTQNCVSSGMDVAMLVPRYVSRRRGSVIFALLGSWPTPGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X267</accession>
    <name>A0ABR1X267_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004474</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672407.1">
        <property type="nucleotide sequence ID" value="XM_066808789.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041849"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF6">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="719" mass="80509" checksum="2F465E0CEC16DB0A" modified="2025-10-08" version="1">MNVESVSRDSSSNGPATPINSRKERGAIAAQARKQRCSEDRPRCTSCQRMNLDCRYREPQPTKKDKTLVEILDRLKSLENKVDNISLGSTYPQASGYETRSPNPPGPTTATIAPDARDQSRATPWHSSGVHSPAPMGHAATRQTHYSYSSATYKMLSWPFVQQFLGSSKKIAAMVEPLAKKNGAAVMLDLHARATPLPQDTFEMAESRRGSAAPNLEVPLRNPSGGLHMDPMSFSWENMHRLSKAYFDTFNLLYPFMDRAQFQTEILSSVAANGFDESLNSTLVCLVLALGGRQSADNPYGKTQRDKGGSLERPPGLAFFNEARKRMGYNLTQCSLENVQVFSLASKSILRNLLSPRGILAHDYLCLAGVPGAPDKVIHDGTQTQEKGITILTTCEIHSNPDELKSHRADLVRRMFWHCIMTETYLNLEFNLPLTGLEKFDDMVGLPDFSAGSFSEEDYIGNQASHFQEHFASQIVLRRLLVEFHTTLTSALGVAETGQPSIQAADTLASSNPGPTIKQFAAQLDRWRGMLPSHLCWQDDYTNRGHAYPPPVPSMHDSFVFTADLDAPPVIYPFAADIQAAILRTRYYYVRFLLHRPFLFKALHYPESITHEDAEGVAIALKSTLSWPITTSPVRNQKRLIPCLYCWSQKFLAMLLVLHLSQQVPILVRIRATHLGDRFDAAAKQTTALYIDWIRDLKDVDPTARWCWSILREVYSLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X368</accession>
    <name>A0ABR1X368_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672673.1">
        <property type="nucleotide sequence ID" value="XM_066809055.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042115"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="8"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="237"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="283" mass="32184" checksum="26E35FB81F460BAF" modified="2025-10-08" version="1">MASNTTENCGICQENAIDAPATLVTLPCAGHHAFHPDCIKQWLGCGHTLAAEHIQPGSVIDSTVIAGPCKPNCGGPVLSRTDQDFMTNYAPSTTRLLISIARREAREAAERRRDLERQAFEERRHQAALERFQHMFQDFVQRQEQVLQRELREMQELRGQLDDDENEQRELSNTFDTNEHQGQQGQADEPVPRQRANHPVRDDIPELMNALSREVRDLLLSSIRRPGHSRPRGQRTQPQQQEPPQEQQEESLLLKAFGPNVMELPTIFADSNESANDDEQSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3I6</accession>
    <name>A0ABR1X3I6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_004939</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672872.1">
        <property type="nucleotide sequence ID" value="XM_066809254.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042314"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.220">
        <property type="entry name" value="Fungal kinase associated-1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031850">
        <property type="entry name" value="Fungal_KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043024">
        <property type="entry name" value="KA1_sf_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16797">
        <property type="entry name" value="Fungal_KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="110"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="65"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="564"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="956"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="566"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="599"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="649"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="956"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="980"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="990"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1003"/>
            <end position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8089978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1240" mass="140330" checksum="84CC91729369D21C" modified="2025-10-08" version="1">MDKRGVRKSQHTRPPLSDATHRVVNAPTQYTAKTTSQVHREVANPLRIGRAPESVAPHCEATLQSRVSASAVSRTVPGPMTDPNADKRASQISTSSGASSSKRKTHVGPWHLGKTLGKGSAGRVRLARHSETGEDAAVKILPKHGVRLTQAGSLQDIDAWDQSKDDFKRQNHMPLSIEREVALLKLIDHPNIMKIYDIWENRSEIYLVLEYVNHGDLFEYINEYQCLREDETVFFFRQIISALDYCHSFNICHRDLKPENILISNTGQIKIADFGMAAIHQGPTHWLQTACGSPHYAAPELVNQNRGYQGHKVDVWSAGVILYACLCGRLPFDDRDGDLRKLLKKAQIGRYSEPEHLSWASRDLIRRMLQPNPDRRIDIRDIWEHDLITAYDTYDDLKQLSKDDFQLDAIRQSGRQTQVALEDVDLDIVRQLKSMWHTYSEEKIIEELIRREPSDKKLFYHLLLRYTENQLENYRCNLPHSPSDFHHLQPATWKRKLTTLEFPGRPGRVPSRFTVISNVATDENGVETATDAGGTIRSYDPFKSSRIMGENEASHAKITVHRNGSVAKSSTRATNSGRVRNGSIRSNSTYSRRGRYNRRLATTTGLGSTRRSLTSLRSGDGTPYKRNASRHKRGVDFSHVRRQPVKSRATGSIGRTSTSMAGDDITHNQFHKPSVNPMKQGKRPKENSRGNHGSQTMAEFSRPNDTCLPWNDELRHFSHSIAKDCDQAFNSSLLLPERVDEASVGSLPIPASNTGTHYDTRSSSIAMGTPTHLQHSGRMALRNLQQWDMRPLPPTPAPTESKLHEITMTKKRIEKHQLKSNEFKGHVDRVVSNLNKLVPSSKKADEETRAVSAPIYSRYSTQWGKDTVPLPSIHEAQYSNVRNSSAPVAVKNTLGTSTEDKSLEYLARQENTIRVVQSPSVKRSPVKAPAPLNVRKCSANSGRQVRAETNLHQQFAHDEVTKTIPEEPSTISQRSSSGGMRKKSSWFKRTSKDKEDIFKSHHGSASGQTEELSYSESNVSSAPAMPPTKKKSFSFAFWRNSKDGEEMKLSLGALTNYDHVLTDYQVRSLTTPRALSLFVCSTTPSRPPRADKWNESVATRNIEPQQTWLARLFRVKPATDHLCFNIPRRRVRQEIVILLKEWRRYGIRDIQVDKNRNIVFGRVSKHNYLSMKEVSFAAEIMTVIEHGKRNPLSIVRFTQERGAASSFHKVVETMHAIFDARNLLVTDKRKVKMMIKTLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3P3</accession>
    <name>A0ABR1X3P3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pyridoxal kinase</fullName>
            <ecNumber evidence="2">2.7.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004997</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyridoxine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.35" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672930.1">
        <property type="nucleotide sequence ID" value="XM_066809312.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042372"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01173">
        <property type="entry name" value="pyridoxal_pyridoxamine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004625">
        <property type="entry name" value="PyrdxlKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00687">
        <property type="entry name" value="pyridox_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534:SF2">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyridoxamine kinase/Phosphomethylpyrimidine kinase" evidence="7">
        <location>
            <begin position="101"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8090036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="294" mass="32199" checksum="279FD72465B5F069" modified="2025-10-08" version="1">MNSEPPVPETSVLAVASHVGEHNVGNKIAVFVLQSLGCDVAALNTVQFSNHTGYRQWKGTRVTAEEITELWDGLKQSYLDRFDMMLSGYVPGAAAVEAVGNIAKELKKKSQAKPGSFFWVLDPVMGDNGKLYVADDVVPAYRGLVHHADLILPNQFEAERHARLLSEVKITDFASLRTAVETLHSRYNLPHIVITSVSLPLDSHKASPDGSSPSRTMSVVGSTRTSTGKSRLFSITFPVFDAYFSGTGDMFAALMVVRMREAVASSCLKDKASWLSEDDVDALELPSLRPRRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3Q2</accession>
    <name>A0ABR1X3Q2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672893.1">
        <property type="nucleotide sequence ID" value="XM_066809275.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042335"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="282" mass="30425" checksum="082720C2DA285A00" modified="2025-10-08" version="1">MAAPTPPKAMSSRLLTMKFMQRAAASAPTTPTASPKSEEQSSKRRKVSHESTANAPVDFMVNQQAVQAAIDEGEKKREEAIVKHAAELGDARWVLDVPDSPFNSLYQVKKPLNVVQVGYAQIDSPDATEHDTDSVGDSLEKGHLFRRYNMDKKKVPAESNNSNESSDDDDDDNEDSASDSDASEDDGPGRKSYGGQKSPATPRIPSKRSAEREKARELAEKRRKKEVKLNSAKPAGLSSISSGGGISSGSRQGQPGAASPSFKCHNCGKPGHSFKSCPNKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4I0</accession>
    <name>A0ABR1X4I0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673163.1">
        <property type="nucleotide sequence ID" value="XM_066809545.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042605"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="51"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="323" mass="36815" checksum="0726341A141A3F58" modified="2025-10-08" version="1">MGKKRVLISYGVDVDAVAGWLGSYGGEESTSDISRGMYIHQSIIFKLVLAVTNELRAGLFAGTIGVQRLLKMFAKYDMKTTWFIPGHSLETFPEDMAAVRDAGHEIGLHGYSHENPSDMSIEQQRDVLDKTYKMLTEFTGKPPRGSVAPWGQLLLDYGIEYDHSMSHHDCQAYYLRTGDTWTNIDYKQKAETWMKPLVKGQETGLVEIPASWYIDDLPPMMFIKGAANSHGFVNPRDIEDLWRDQFDYFYREYDEFIFPITIHPDVSGRPQVLLMHERLIEHFKKHEGVEFVTMEQICDNFKSKNTPAEGAVMPAKPGAMLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4X4</accession>
    <name>A0ABR1X4X4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_005441</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673374.1">
        <property type="nucleotide sequence ID" value="XM_066809756.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042816"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="16">
        <location>
            <begin position="289"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="508"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="517"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8090480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="627" mass="70082" checksum="D1EDDF4AD50BC5E3" modified="2025-10-08" version="1">MDMGMGGMDMGSGMFSQDNMALARAYWYIIAGVLALLLLIRLVNSGQHWLSSIRYPTKPTTWYWQTWATLTAVAREISYPQLYVPYKYLSWMTPPPMGRVLVLLAYWAVIIYMMTAGAIKKDVYYWERIGFRNAWVTVTQVPLLYLLSSKTSLVALLAGTSYERLNWLHRWVARTIFVTATVHGFHFWTEWVLADFVQDYLQWMPMVKFGLGAWGILLWMVLTSLRPFRSMAYEVFVVQHVVAAIFFLWIIYLHVPANARYNVWFAIAALCFDRAFRMGMLLWQNVKFTKPNPSRCRGGQRFGHQTQIAAVGDAITVLTIKDVHFKWRAGQHLYLWLPSVGAFETHPFTIASAHQMPETCICNSIQLVIRSHSGFSKRLHAYAKKMEAGSTSGKKKQTLTAWVAGPYGRPPRWDIFETLVLISASTGASFTLPILESVLDSKATICTKRIDFLLAARQGDEVGFYLGRLHEALAKAAERGIELSVSIAVTGSGQLEAISESLLSRSNAPSMGTLEGTDEKNIREKTTDIDPGPSGGCCSTTNRHRRVPSRTNSTDSHIHHSAARPNVPGFIRNAVEATGGETGVVVCGGASLVSKVRTSVARLSDERAVHKGTGAQGICLHVEEYCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X531</accession>
    <name>A0ABR1X531_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005413</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673346.1">
        <property type="nucleotide sequence ID" value="XM_066809728.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042788"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8090452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="501" mass="52908" checksum="0B4A771567F01D49" modified="2025-10-08" version="1">MGARTVASGANHERPNHSAHSIMAGDVPGDDDKPSSTQRHMKNSNSAAYRITNILCAIIFVAAGAGGLVTIPQIQLLETAVCREFREGAEVAGLLDESGSSLEPPSCKGKEVQSTVAYIIAVGAALESVIGFLGAIPWSTVADRIGRKPVFVLALIGITADNLIWLAMIWLQLNFHIPSWTVWFASAGLVLGGGNAMLTSVVLSTITDAAPEEIRASLFMRVHAAALSASLLAPSLASALMGAFGPLDPDALGRHDTASTRTSSDGPFQISSAIHALTQASKSLRAFLPFVSRPSLVCLLITVLLSYSLIPATMQLLVQYVSIRYSIGINDTGYVQTVYGLAQLLQLFLGLPLLARLVRSRAGVGSDAQRDLYLARFSFLVAIPGALLMGAAANLGFFVAGLLVLALGAGSSSYQRSLLSSFFDAEYHSRLFSLVAMVDMVGSVYSGPMLAGLFTSGMELGGDGFLGLPYYALASLMGVCLALMFFVRLPHVYEYKPVGNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7Q0</accession>
    <name>A0ABR1X7Q0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mitogen-activated protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_001794</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673405.1">
        <property type="nucleotide sequence ID" value="XM_066806109.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039169"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF48">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE BCK1_SLK1_SSP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="1481"/>
            <end position="1750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="189"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="331"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="487"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="831"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="910"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="948"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="975"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1048"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1331"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="511"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="539"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="587"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="694"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="863"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="915"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="988"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1004"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1015"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1257"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1331"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1372"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="1510"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8091433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1772" mass="192091" checksum="ECBEA9F440BC307E" modified="2025-10-08" version="1">MISSRTALTRSESTSEATASARYPNLRQRLQDNVNTLDSLINDPLPILLIQLPVLLLLLPPKSQPPPPPPPPPPRPTLPLRWLRGLNTLDQARRPPRTTLPLPVRQLCRRWWCGNPTPAGVHGQSRCLRLGRGLDSQQHQSARDTGRRAACTSSAAALHLCHHVFQHPAARPQPTLQCPASAPHVAALHGPHERHRHEHEHPPAAASLPQRADHDHDRRPAAAASPVRATPNSAMGGSATWQGSWGTMYNTRHGMTSIPPPPSGGPHVAYNPRLHQQASMGNLQIPPPPTQFPMPQQTSDQPSGMSATYIPTATPTAKGVGIPAFGPDESTTFSATSHGSWPTQGSNTIDTANTTPADGESRDRLYTNALNSQNQNQRMMSTASNATNTPSNIPPEMAAKWPLDHVLLWLASNQFSKDWQETFKALNLCGAKFLELGSGQHGRGNFGMMHQQVYPRLATECINSFTGWDPTREREEGKRMRRLVRNIVHGGGVATSTSGSRPDGHSRKDSLNASQGAGTDIESPNTPIKAPGPGFGSRRFSQTRSTTMPTLSNTMSSDSNHRTLLKNLDVERSQRHSPGVAEAGNASSRGSAPRSDSPGGSPRPPNSGMLSATSPSGRFLGHRSRNSTDSVSSNAAIYGSGVPPEASAYLRSGLNGSRSPHEPPGDRSAGSEHPASAKGDSSLFGFLKRNKHKQKEDGTYHSPKESDSPTSPEMLKSSGTGGSHDAANFDALSFRARKENAPRAYLLATVNGWDYRMCVVTDCETAQEIRENICANLGIHDARSVLLYLTELGKVEHEEPLEDQSLLIHKRNKGDSNGSLKLFVRVGAPPPVTPDVPGSLTPGYVPPGASMDEDTYARLSGQRSRSSSSPPTSRVNTVGDNGPDPNELAQKATAYKAEVEKQQQAYLAKRKQALGKSSPQESAATSPYGVGIVGRNVDFDQPRVSPYEEKKTQDMLFPQRKAPAPPGVETATLIKANSLSRRTGHNLRASQGSIDGFTSQRRPTTSTSASGSSGENNQQQEMSQRRPSSASREPATSAFGALVGMGSALSHFGRPTKQPHNSNNNNNNGRPVSPPPQPNRNNSGPAAGSAHEEQRDLAFVIPDYSPGGTPLNKGKPRDKVAGDGDGDDEEEEPLAKKRDGIVQRAPSPGNPSPTTAHPTGTAPPPQSPPNRRKSHGPDIDFTDTDVTFDQPMAPKVQKDDDSDDDSDDGLFAIPVRGRTPSVKVSSSEEFDRNGKRPSLTLRTRRSKKQLSVSFDALESDDGLIPADEESSGRRRRTPATPSDSDDGKLGRRRSFIERDVWANRPPPEALLSNLDAFFPELDLDQPVLDESQLQEPTSPADPDNTNSSNNTGATENERNDNNQAATKTTRLAPDESTLKAERPSSINSVAQRSIRRSGGGLGRMKSIREVARGAHEANKRFTAASAASGAGGPTSMIQRRKSTKMFGANLVQIRPERGSMIDIMPQIPQDTLPKRQTTFRWFKGELIGKGTYGRVYLGMNATTGEFLAVKEVEVNPKAAAGDKNKMKELVAALDQEIDTMQYLDHVNIVQYLGCERKETSISIFLEYISGGSIGSCLRKHGKFEEPVVSSLTRQALSGLAYLHREGILHRDLKADNILLDLDGTCKISDFGISKKTDDIYGNDKTNSMQGSVFWMAPEVIRSQGEGYSAKVDIWSLGCVVLEMFAGRRPWSKEEAVGAIYKIANGETPPIADEVREAISPYALGFMLDCFTVDPGERPTAERLLMQHEFCDLNEDYNFFDTDLYAKIRGTFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7S9</accession>
    <name>A0ABR1X7S9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Indole-diterpene biosynthesis protein PaxU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001791</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endomembrane system</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673402.1">
        <property type="nucleotide sequence ID" value="XM_066806106.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039166"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008547">
        <property type="entry name" value="DUF829_TMEM53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265:SF30">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05705">
        <property type="entry name" value="DUF829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="30909" checksum="3587EBF7925AC52D" modified="2025-10-08" version="1">MALQGFVELSPNILLYTPSEHLVGHLIVLCTWMGAADKHIAKYADIYRQKAPGAKILLLKSAVGSMVSSYASQRRAMRPAQQVVCQLLQEHYSLQRGGASSNEQPRILLHMMSNGGANSATNLLVDLEGRLQAPIPVVGLICDSTPNASSWKNTCHAFMYSFPCGFPVNILTTAFVYATITLLYVWIAMGNEPPEDYWRRSVLDGKLVRCRQVCYVASKIDKMTDWRDVVSHAAVARKMGWMTKEIIVDDTPHCNHISKHEEVYVNAVSNVWEGRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8Y2</accession>
    <name>A0ABR1X8Y2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450 3A19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002264</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673875.1">
        <property type="nucleotide sequence ID" value="XM_066806579.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039639"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF162">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8091903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="444" mass="49293" checksum="B7847AD954A2D704" modified="2025-10-08" version="1">MRALYRMRFNSELQALHQKYGPAVRIGPNEVSFASLEAETTIYAKQEDGRFSKDGTFLTLFSDLVLNAPTLITIPDPALHRRLHKVIEQAFTPQARAKQEPIQKIHIDMAISEIDEIVDRGSTMDLADTLETMFWEIIGDLAFGEPLMSGKRPTYESLKKRGKASMPMIEALSFCLTMPGIAQALQLARGLVTAMTPSSQLSKLVPSTKLRDCIERQDGREDFLTAIMGSEKQGLTLDADAFFSNAMGLTLAGASRLAGYQTTATTLAATFYHVLRYPDAYRRLCAEIRSSLASEDDITGERLARLPSLTPASAKPCTAQRTAPEGIIAGLYIPAGTIVSADLYTIQRSLEYFADPATFRPERVSAEFHADNPVAYRPFLIGSRACIGRQMAQQSIRLIVASLLWRYDFELLDPEGFVWERDAGSSLIYTDYQVNVHVKRTSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X918</accession>
    <name>A0ABR1X918_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mandelate racemase/muconate lactonizing enzyme domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002378</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673989.1">
        <property type="nucleotide sequence ID" value="XM_066806693.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039753"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03327">
        <property type="entry name" value="MR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023444">
        <property type="entry name" value="L-Rhamnon_dehydrat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046945">
        <property type="entry name" value="RHMD-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011968">
        <property type="entry name" value="PRK15440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794">
        <property type="entry name" value="ENOLASE SUPERFAMILY, MANDELATE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794:SF58">
        <property type="entry name" value="MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00179">
        <property type="entry name" value="mandelate_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00006">
        <property type="entry name" value="rhamnonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="4">
        <location>
            <begin position="185"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8092017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="442" mass="48871" checksum="210DBB551144FCE5" modified="2025-10-08" version="1">MSSSVRNFPTIKAIRTFIIGGVGSGGDYHNVKGGHWLIDTDISTPCSIWDQYKKSRTSWGINVLGSFLVEIEATDGTVGFATGFGARVGTVDIHLVMTLGPPGCWLVHQHFERFLIGADPRNTNLLFEQMYRASMFYGRKGLPVAVISVIDLAIWDLLGKLRNEPVYRLIGGAAREKIDFYCTGPEPTAAKDMGFWGAKVPLPYCPADGHEGLRKNIAFLRKHRESVGPDFPIMVDCYMSLNVSYTIEIVEACKDLRISWWEECLTPDDTDGFEQIKRAHPTVKFTTGEHEYSRYGFRKLIENRNLDIIQPDVMWLGGMTELLKVASHAAAYDIPVVPHASGPYSYHFVISQPNTPFQEYLANSPDGKSVLPVFGDLFMDEPIPTKGFLTSADLDKPGFGLTINPAARSKLISSAYLLNPPPMRALEPAEATETEAAPSAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA43</accession>
    <name>A0ABR1XA43_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674241.1">
        <property type="nucleotide sequence ID" value="XM_066804468.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037528"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="193" mass="19562" checksum="81A46B9C39586DC7" modified="2025-10-08" version="1">MSSITAEPLQDAQDGAVGAPAGGPGGPAGADTVVLLGELAGDVLGRAGGGADGVADAGGGAGLAGVEGVDGAVDPGLEVLHMLRRRAAVEVQVVPQPVGLDGVAHVLRRHVPVVTEYTRWVGRRVAAAAWEDLGSLVCGRRRESLGGEECGQGGERGEGAEHFEGSWGSCALWKYCNDLGSWMSVGSLMFEMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB48</accession>
    <name>A0ABR1XB48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674643.1">
        <property type="nucleotide sequence ID" value="XM_066804870.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037930"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="110" mass="12537" checksum="BBF064AC9B3F2D99" modified="2025-10-08" version="1">MLAWGKQPAARTMAVEHTFPPELWVIICTELADQQDPRFYWRHSIPEIQPARNALRQLCQSSKTLRSIALPLLLRFRSTREERGGFLGFGKNILSKPELAVLVRGIEVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB50</accession>
    <name>A0ABR1XB50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674586.1">
        <property type="nucleotide sequence ID" value="XM_066804813.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037873"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14372">
        <property type="entry name" value="CUE_Cue5p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041807">
        <property type="entry name" value="Cue5/Don1_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461:SF5">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="80"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="446" mass="48768" checksum="D6C85E692BEC974D" modified="2025-10-08" version="1">MAAPTDTTKQHTSDPGSESPTTVKPFEMSDDDDDVQETGVLSDSGAHQQPATTASATPAAATTAAPGSASASAPKPATAQKNEAMLKEAFPSIELSVIKAVLIASGGRIDPAFNALLAMSDPDAVQNDPVAAEEREVPPPQPPRPTGPQATMSQVEADELYARQLAEHYDNVGAYENRTSNRGHPQQQQPRRQQGLMPDEEYEREPNFIDDELPVIRENLRKGFVETQTKVNSWFTNLKKRIDGEYDSEEDESQPSRRQQQPYRRSGEGSRRSNDYDRYDADPQVLSDDFAGMRLNQDGSQSRSGNPNVYQPPPRSTQSKSPRPDRPKVSFQEGHESIDNVYDASPKLPPKDNAPSPGPGGNNSKPSKWQPMSTVEPDPITEHDPFSLGDSEDERDTKTPSKHGKTESKDIKMDDAERLKQATADAMADSLMDESAKKGGEEAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBN2</accession>
    <name>A0ABR1XBN2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinetochore protein fta7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674824.1">
        <property type="nucleotide sequence ID" value="XM_066805051.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038111"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025212">
        <property type="entry name" value="CAD_CENP-Q"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13094">
        <property type="entry name" value="CENP-Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="500"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="642" mass="70213" checksum="538BA7DA4D93A131" modified="2025-10-08" version="1">MAPETANQKRKRGRGATAPRDNETASQTPSGPAEQGAAALPNGEPEAVEPEEDARPRKRGRPAKTAQPEPEPEPEVPLAPEPVVADAAPAGKRKRGRPSLAGGNKGAENPESEAPRTNGDLGAKRGGRKGQSRQQAPDDTPNEPDVEPEKSQPKRRGRPPRTAKADGPEGEAEEADDENEGNSSLLRRSARERRKAGDKGSPGGKATNQEPEAEGSGSSRDLPQGGRERRSPRGGKKKPEKTAEKQDDASGRPPLRRGPKGKGRPVLEDVPDDLPDHASTPRPRPSKSAVDLQAIEVTRVKQRKRGRPSLTSREAETNAKPRRQRKSKEQQQAQEEDAEAEDEQAAQPERRSEEGQNDAAAPRKRKSKHAAAAQAEDRSQSPDPAEAPFRQLTTRTRRVPRDIIDKKWTPLDATSISSITDLLNSASRPVLLRLNNQQRHAQATAALNIVRQKLRSKLSRGMPFPPPSTSGRREDELQFERTVDGIQSLEAQLDPLLHGVALLKQEKERAERELDRDYRTLNSLSANARSENRERRERLRKMHVLVPEPSRREKERDSKAAALGDLVPRGPGEEGGKAFVGLEDNDELKGLAHQIGNHMESMRSNLQQVEGVAPAIAESRAALKTVLMPNLDPAAYEKVLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC31</accession>
    <name>A0ABR1XC31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000823</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674911.1">
        <property type="nucleotide sequence ID" value="XM_066805138.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038198"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF80">
        <property type="entry name" value="GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047048951" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="577" mass="62414" checksum="16F9AF815801DFF8" modified="2025-10-08" version="1">MLSRLFGALVLAATTAVAQNSSASYDYIVVGSGAAGAPLAANLARGGHSVLLLEAGDDQANNPNISTLANFNLATNDETTRWDFWTKHSEDPERELKYLRMVWRKTDGSFYTGLDPPEGAKQLGIWYPRAGTLGGCAMHNAGVCALPADADWDIIVNKTGDESWSSANMRKYWVKMEKNDDIRTMAGQLAEATGGNKSDLVDLAKRDMNAPNPGRDRDTGVFSLSAHQNKEGMRTGTNTYLKATLADTAKYPLTIQLETLVTKVLFDEKAKEPTAIGVEFLEGKSLYSADPRYDPKVQGKPGRAYAKKEVILSGGAFNTPQILKLSGIGPAAELKKFDIPVVKDLPGVGERVADNYENNLLALAAKPLNGSAGPISVMLQTPTALENKYGRNIYAWCNSFAFEGYWPGYPDDYGAAEYECAFVHMNPKSQAGYVRLRSADPRDTPEINLRFYETGTDQDLTEQLDAIKTFRKAFASAPSPITPFNELHPCPGALHDNEAGTGEYLKLQAHSHHVTSGCAIGGDDDAMAVLDSKFRVRGVRNLRVVDGSAFPVVPGAFPVCPTMMLGEKAAEDILAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCP1</accession>
    <name>A0ABR1XCP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Golgi to ER traffic protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_001106</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675194.1">
        <property type="nucleotide sequence ID" value="XM_066805421.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038481"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028143">
        <property type="entry name" value="Get2/sif1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28263">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28263:SF1">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08690">
        <property type="entry name" value="GET2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="37624" checksum="0DCFDED652D7FBFA" modified="2025-10-08" version="1">MTETVQAPEDAAAARAAEQARLRKERREAKIRAGGTARLNKITGLGGGLQRDPEPQAAATQPASTTAAPTTTTQATSTPTAAAPNHDDPEEVDISQHYYAPRKSGGAASLGDEPAMSESQLRQMMLGFERAAPPGIGTPPSRNPYVDPSRAGTPSGMPPPMPPGMEGMENDPMMQMLQSMMAGGGAAGGGANPFAGTGMESLLGGLGGMGGMGAGAGDPNMQQAAQAVADKTANIWRIIHAVFALGLGVYVALSTTFTGLKSERDMLALHDADEDLRKSASVFFYLFSSVEAILLTSRYFLDKHRSPPSGIAWTLVGFLPSPLSSTIRHALRYGQMFSTVRNDALVCVFVLGVCCWLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCW8</accession>
    <name>A0ABR1XCW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Eukaryotic cytochrome b561-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_001194</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675282.1">
        <property type="nucleotide sequence ID" value="XM_066805509.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038569"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08761">
        <property type="entry name" value="Cyt_b561_CYB561D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045150">
        <property type="entry name" value="CYB561D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422:SF45">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="12">
        <location>
            <begin position="4"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8094509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="207" mass="22546" checksum="5D31ECFD1A672C2A" modified="2025-10-08" version="1">MAKLIQSSGTGILAEGAAILLVASVWAAVFLHQPIILFSGHPLAQSFGFLVLVQSILVLQPTQSAQQKQVGQKIHAGLNLLAFATFVAGVVIIEVNKVKSGGPHFHSVHAYLGIIASIWIVVQYVVGFTMFGLPALYGDEANAKKIWKYHRMSGYFLLPFLMATIISATETDYNKNVLGLKLWAMILIMALMVVGIYPRVKKQKLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCZ0</accession>
    <name>A0ABR1XCZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">glutamate synthase (NADH)</fullName>
            <ecNumber evidence="19">1.4.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">PG997_001158</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Nitrogen metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.14" evidence="19"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675246.1">
        <property type="nucleotide sequence ID" value="XM_066805473.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038533"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="entry name" value="Glutamate synthase, alpha subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012220">
        <property type="entry name" value="Glu_synth_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008730">
        <property type="entry name" value="PRK11750.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000187">
        <property type="entry name" value="GOGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="Alpha subunit of glutamate synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0288">FMN</keyword>
    <keyword evidence="17" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="13" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="15" id="KW-0408">Iron</keyword>
    <keyword evidence="16" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="21">
        <location>
            <begin position="54"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00024383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK8094473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2118" mass="233237" checksum="08A4D0ABBD9E2BBD" modified="2025-10-08" version="1">MGLPSDFDDRQTHIDSEGDAYHPYEYQTENNGSWAGALPVKQGLYDPSLEKDACGVGFACHIKGKASHKIVSDARNLLCNMTHRGAVGSDARDGDGAGVMTSIPHRFFIKNFQNEQGIRLPPPGQYAVGNLFFKPDEETLHESKRHLEDIAESLGLKVLGWREPPVDSTLLGPAARSREPIILQPFVVLTSAYGAENAPEVTDAEKFDERLFERQLYVLRKRATHTIGLHNWFYLCSLSNKNIVYKGQLAPVQVYQYYHDLVNADYQAHFALVHSRFSTNTFPSWDRAQPLRWAAHNGEINTLRGNKNWMRAREGVMQSDVFGDELEHLYPIVEDGGSDSAAFDNVLELLTINGVLSLPEAVMLMVPEAWQGNTAMDPKKAAFYEWAACQMEPWDGPALFTFADGRFCGANLDRNGLRPCRYYVMDDDRIICASEVGTIPVEPESVIQKGRLQPGRMLLVDTQAGRIIDDSELKAAVSSRHDFRTWLDNELISMPKVLSKVSETMDLSPKPDASKLQEDPLLLAFGYTHEQVSLLLAPMASDEKEALGSMGNDAPLACLSNAPRLLSEYFRQLFAQVTNPPIDPIRESIVMSLDCYVGPQGNLLEMDSSQCGRLHLPSPILSIPEFNSLMNLPKLYPQWTVKTIDLTFPKSEGVAGYLKHLDHICDEATAAIEGRDKIIVLSDRKTSADRVAVSSLLASGMVHHHLVSNKWRSLAAIIIETAEAREVHHMCVLLGYGADAINPYLSMECILKLNREGLIRKKLSDDTLITNYKHSCDGGILKVMSKMGISTLASYKGAQIFEALGIDDEVIERCFRGTASRIKGVTFELIAEDAFRFHERGFSSRYTVGPTGLPESGEYHWRDGGEAHINDPTSIANIQDAVRTKNDKSYEAYSRSEYEQIKACTLRGMLDFKFDECTPIPIDQVEPWTEIVRRFCTGAMSYGSISMESHSTLAVAMNRLGGKSNTGEGGEDAERSQVMPNGDTMRSAIKQVASGRFGVTSAYLADSDELQIKMAQGAKPGEGGELPGHKVSKSIARTRHSTAGVGLISPPPHHDIYSIEDLKQLIYDLKCSSPRSRVSVKLVSETGVGIVASGVAKAKADHILISGHDGGTGASRWTGIKYAGLPWELGLAETHQTLVLNDLRGRVVVQTDGQLRTGRDVAIACLLGAEEWGFATTPLIAMGCIMMRKCHLNSCPVGIATQDPELRKKFTGTPEHVINFFYYVANELRAIMAQLGFRTINEMVGHVEVLKTRDELRTNKTANIDLSLILTPAHKLRPGVATFNVRKQDHRLYVRLDNKLISEAELTLDKGLPSRIECDIVNTDRAMGTSLSYQISKRYGEAGLPLDTVHVNIKGSAGQSFGAFLAPGVTLELEGDANDYVGKGLSGGRLIVYPPRSAVFKAEENVLIGNVCLYGATLGTCFFRGIAAERFAVRNSGAVAVVEGVGDHGCEYMTGGRVVILGSTGRNFAAGMSGGIAYVLDIHGDFHSKLNMEMVEASDVSEPNEIAFLRGLIEDHHHYTGSELAARILVDFNRALPRFVRVLPVDYKRVLEEEAAKAAEAKRAEYNLPIVSGVQAKKEDKSNKLQDMEEAVGDNAAEKKRSLVLDKTKGFMKYQRRSEKYRSAKTRTKDWQELSTRLDEDELKYQSARCMDCGVPFCQSETGCPISNIIPKWNELLFAGQWQDALNRLIMTNNFPEFTGRVCPAPCEGACVLGINEDPVGIKSIECAIIDRGFEMGWMVPQPPEVRTGKKVAVVGSGPAGLACADQLNKAGHNVTVYERADRPGGLLMYGIPNMKLDKRIVKRRTDFMAAEGIVFKTGVAIGEDVTLLDLKAQNDAVVIATGATVARDLPIKGRNLEGIHFAMEFLHKNTKSLLDSELQDGSYLSAKDKNVVVIGGGDTGNDCIGTSVRHGAKSVINFELLPQPPPQRGRDNPWPQWPRIYRVDYGHSEVAQHMGKDPREFCIMSEEFVDDGSGRVKGINTIRVEWTKSASGGWDMKKLEDSKQFFPADMVLLSMGFLGPEARVLGDDIEKDGRKNVKTPAGSYATNVEGVFAAGDCRRGQSLIVWGINEGRQAAREIDLYLEKCTSLPVTGGIVKRTAQEIFQAVHGDKHTHTVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDL2</accession>
    <name>A0ABR1XDL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675553.1">
        <property type="nucleotide sequence ID" value="XM_066805780.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038840"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047403732" evidence="2">
        <location>
            <begin position="21"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="432"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="531" mass="54084" checksum="A3C2C9148C7D3434" modified="2025-10-08" version="1">MRVSHIVTLAVALAAETVLGHMNMADPPPLRYKGNPNAVKAGKVDSDITSPNTATTFPCKGAIPDFDDPIAGAPVATWYPGEQHNVKIEGGASHNGGSCQLSLSYDKGQTFTVVFSKIGACPTDPNIPFTLPADTPSADKVLFSWSWINHTGNREFYNNCAVLTIGAAKKNKKRTAPAVAFKDRPAMLVADLYHVAGAACVKEGVDALYPEPGPDFVNVSSSAALPDDCVTGQPMSSNPIVGGSGGSAGSGSGGAPASGSASAPAGPGATASKSAYVSSSSSSSFSSSPALLASPSMFSSLLMPLPTSSLHSSSPSASETSCTSPASTPSISSSPSGGSTLGYVDKVGICVFFCGCCCVAVAHCDPDHYFPPNPHSVADADQQHLLIRLLVCLSIYAPNSAPNATPSSGVPTTPSTTPSATSSEVVGLPSQTSTATSSAAPPAGTGSPGGNGGGSLSGPCTPEGEWNCLSDGTSWQRCASGLWSAVMPMAPGTTCTPGQSSTLSKRREQYVRRRNAVRRNAVRRDPVRRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDV6</accession>
    <name>A0ABR1XDV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001542</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675630.1">
        <property type="nucleotide sequence ID" value="XM_066805857.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038917"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF2">
        <property type="entry name" value="CELLULOSE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047324995" description="SGNH hydrolase-type esterase domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="29"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="249" mass="27130" checksum="09EAAF15E88D07BD" modified="2025-10-08" version="1">MVSVKLLSLAALVGAAVAQNTTALRYMPFGDSITEITCWRSKLWDKLQGTDYANTNFVGSGKNENNCRNTKYDRDNEGHSGFLAINIANNKQLVGWLQRNPADVITMHLGTNDIVQQNKPVNQIIAAFTTLVQVMRDSNPKMKIVVAQIIPMGMGNFNAKIQALNQAITPWAQAQNTTESPVWVVDQYTGYSGSADNRDGIHPNAGGDDKMVNIWYPALLGAFQAARADQVAAAAEAAAAERRVMPFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE49</accession>
    <name>A0ABR1XE49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675723.1">
        <property type="nucleotide sequence ID" value="XM_066805950.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039010"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="203" mass="24316" checksum="01BDFF874D00E8BD" modified="2025-10-08" version="1">MTWLINRGAMVDSRIVYHAEDSVIQVHYRRGYAGDFFSYDYDLSDIDSYIFDVDMDYKAFDKFQLLLSKGGQIKYDEKDEELEEYSAVQSFQDEALIYEFENTPTSDLYEYSPEAWSIVKRRTFRMVFRAKSCDGTYVESPAEAYKDFERWRHVIRWLLKERQSEWPPEVPFPSGTALELFERWWERRHRGGWGPRGLRQVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE96</accession>
    <name>A0ABR1XE96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001627</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675715.1">
        <property type="nucleotide sequence ID" value="XM_066805942.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039002"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="604" mass="68177" checksum="4FF229774F5AE8EA" modified="2025-10-08" version="1">MTDYSDEYRPRDLIPLQRTFLRLMVDRPELATHVKSFIWTLMWRGFGEQDLSEIDMRTCEVLGQNVACLDPASLRQIGDQPYLFRVLSAEASPHPARVDLRGFSIFENGAAGLPPPPRFEATRDRFRTCPFLADWGSMNAANVDCRARGHNRAGQLPDIWMEDGSPVRITPDLLLFHKACQLRDIYWDAACNTKGSIYQHEAIGPQSLFTTTGADDHRKLRKAVGGSFWSVGTLKKTWEAKIDDLILNWVRNRKRPSENGKTIILSNKTSEFAADVMTMVLFTKPWGFVQNDRDERGMLHAWRVGTSLFGLAVRWRFMREVILSSKLKDYILPKMSDEWGNGWLMAQGAREISDRHTKLQKKGKGESVPSFNDVLQTAIDARIDDEPLNDTQRLAHMTLLIQAGADTTGTGLGATLRLILTHPKVLAKVREEIATADAKGLLSNPVVQYDETKRHLPYLSACIRESLRLHPPIPNLFSRLVPPSGDGKTIDGFPIPPGTQMLSHAVVVQRDADAFGPEPTDEFRPERWLESEERSARMEGYMYTFGMGPRVCLGKELALMEMHKLVPEVLRRFGVEVLEEGRYCACGGIAYLQPGLMVRLTARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ57</accession>
    <name>A0ABR1UQ57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YEATS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_015264</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660463.1">
        <property type="nucleotide sequence ID" value="XM_066819578.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052638"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16905">
        <property type="entry name" value="YEATS_Taf14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016665">
        <property type="entry name" value="Sas5/TAF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23195">
        <property type="entry name" value="YEATS DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016551">
        <property type="entry name" value="SAS5/TFIID_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YEATS" evidence="4">
        <location>
            <begin position="41"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8061043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="272" mass="31482" checksum="851767A1300A3D52" modified="2025-10-08" version="1">MTSSKAAQPRPTRTRSQKRSEDDRSEPENHSAGLKRKRASSPSKMQLERKVKLVTEQRNIDKESPMPEFPMKEWSVKIFLTDAEGGEHPANCFTKVTYNLHPSFANPNQTFTEPPFTCKNEGWGEFEMSIDMFTTEKGGKTTVYHDLNFQSPRYEVLQNVTFKNPSQALLNILRETGPVSTEEDPKVNKVRKANDGKKRKNQWDFEKMADAMTKLDEDDLLHVIQMIHDHKNDDTYTKNDMEMGEFSVDLFTLPDNLARMIWEFLVDQKKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTI9</accession>
    <name>A0ABR1UTI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_015350</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660549.1">
        <property type="nucleotide sequence ID" value="XM_066819664.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052724"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="333"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="69"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="203"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8061129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="400" mass="43305" checksum="1EB63330B3BC80CB" modified="2025-10-08" version="1">MYRACKTGTIFSSRDKGPPTPQLSPQQQPRGAQVHQILSIQSPATVQSGSLWRNPCIGDTLAGNYRVGPDYNVGYSPQETHAGEQQQQQQSQSQHAYDTHHHHRGNPLQHSGPSSLHEQTPPHTHHTMSQHHATTPHQHQILMDPSHLGGLPGTRHMGHPGPSHYGAPGPSHGLPLYPSMTPTQPQSAGSKRSRPDDLDLTVSGLTDLDQSDLDSMQQTPMGSAYTHAPPPPGAPPTHHHHRLPDQGPPTKMMRRDGGDGALSSGGGGAPSVVGQVGMPAPAPRPRGPKLKFTPEDDQLLIDLKENKNLTWKQIADFFPGRSSGTLQVRYCTKLKAKTTQWTDETDQKLRTALADYESEKWRIIANKVGTGFTPVACRERVEQLMGGGGGSPDEGVGEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTR7</accession>
    <name>A0ABR1UTR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660919.1">
        <property type="nucleotide sequence ID" value="XM_066818731.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051791"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF40">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="281" mass="28940" checksum="3341CD54A6CD0933" modified="2025-10-08" version="1">MDIRGVVVVTGAGSGIGRTVAQRVASLGADVLVCADLNLDAAKETVVLCQNARDKDSGGFKATAHAVDVRNEDEVDGLIAQVASTHGRIDVLINTAGFGAANQTPIRDMTLADWRSLDEVHNIGCFLLTRAVLRVMYNQDAVAPTTAADRPPARGAIVMLTSLASEGAFLGVGNYIAAKHAVKGMVQTAAIENGGRGIRVNAVAPSYVSGPMMDQFLEASPEVKKAILGDLCMGRLARPGEVADAVAFLASPASSYVNGHTLVVDGGASLQLANTPFGGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUP1</accession>
    <name>A0ABR1UUP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rhamnogalacturonan endolyase</fullName>
            <ecNumber evidence="4">4.2.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_014717</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1-&gt;4)-alpha-D-galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non-reducing end.</text>
            <dbReference type="EC" id="4.2.2.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide lyase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.23" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661219.1">
        <property type="nucleotide sequence ID" value="XM_066819031.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052091"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10317">
        <property type="entry name" value="RGL4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10316">
        <property type="entry name" value="RGL4_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10320">
        <property type="entry name" value="RGL4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1120">
        <property type="entry name" value="Carboxypeptidase-like, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029413">
        <property type="entry name" value="RG-lyase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029411">
        <property type="entry name" value="RG-lyase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016590">
        <property type="entry name" value="Rhamnogalacturonase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015364">
        <property type="entry name" value="RhgB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36574">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36574:SF1">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14683">
        <property type="entry name" value="CBM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14686">
        <property type="entry name" value="fn3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09284">
        <property type="entry name" value="RhgB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046264803" description="rhamnogalacturonan endolyase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="14">
        <location>
            <begin position="570"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="536"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="536"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8062620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="605" mass="63671" checksum="E7B2E19011CC5DB1" modified="2025-10-08" version="1">MLLQTPLLAAFAFASTAFAAFGFTKSGDNYVVDAGSDNPLIFTVNGKSCDITSIRFRGVELQDKQGSHISSGLGSATVSATTVNNQYVKITCQTSTLTHYLVVRSGDSTIHMATYISAEPSIGELRFIARLNSGELPNEHPYGAVSTTSGSSSTVEGSDVFVVNGQTRSKFYSSTRFIDKDAQCVFGGSDLKHVCMMTPQQESSSGGPFFRDIESNNAGPATNLYNYMNSGHVQTEAWRTNVLHGPYMMTFSRSGVPTGKGFDDSFWGQLSVQGYVPKSGRGYVSGTASGVASNFETVIHWYNGAAQYWTKAGSNGAFTSPAMKPGTYTMVLYQTEFKVASASVTVAAGQTKKQDIASTLPKRNTLWSIGDLDGQPTGFLNADKQQRMHPSDSRMTAWKPVTYTVGSSTVGQFPMALFKSVNDPATIKFNLDAAPAGTATLRIATTLSFAGARPGVKINNFSPATPASPPKIDSRGVTRGAYHGNNEVYDFSIPAGTLVAGANTVVINAVSGSSGATFLSPNFIFDSVELFTAGSGNGGGNGGGGDNSPPPTTTTAQAPPATTTTTAPDSQQTQYGQCGGVGYTGPTCASPFQCTVSNDWYSQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUW0</accession>
    <name>A0ABR1UUW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661310.1">
        <property type="nucleotide sequence ID" value="XM_066819122.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052182"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="21767" checksum="CB3D3B96B93C4CBA" modified="2025-10-08" version="1">MHDLHSPLLAACGASRDAFLQASSEVCLPDIPGQPIDESRWKDVVWRPGLRLAVLGPGHNVAELSTVEGGAEIRHLVISYALAHDTLVDLCYPRQFNREREWMLRRLPNLMSWQIYALPIEPPPSGGGDDTDLKERLRALPIPGSINPTNWVEVSLSADCSLSSWKILSLLRECTETTRNTGYQGISCCPRVRSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXC9</accession>
    <name>A0ABR1UXC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661290.1">
        <property type="nucleotide sequence ID" value="XM_066819102.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052162"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047326458" evidence="1">
        <location>
            <begin position="26"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="169" mass="17581" checksum="E24B441030EF37C2" modified="2025-10-08" version="1">MQYSTSSLAVAAAAVVASLVAPAAAMFDEKACKGIGACTAPSECNYMPNGEPQQPEWDCGSAGTINGQVAAGAELNFELGLSTGTVVDAADFPSSCNLMQPGENATLLVGLPSLKSHDLLDRIDLLTTATNQQKATYQDVTVYGWIEYSCTETTKITNGCYSSTPNPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1F3</accession>
    <name>A0ABR1V1F3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS quinate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_011754</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661761.1">
        <property type="nucleotide sequence ID" value="XM_066816069.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049129"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF21">
        <property type="entry name" value="QUINATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="29"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8065007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="535" mass="58693" checksum="DE91D5C7CF784BDD" modified="2025-10-08" version="1">MAALLKKIVRNDAMKTDPNEIYGWRVYVLTGSACFGAMSFGWDSGVIGGVIELDTFSKAYGLGDPGSVASANLKGNIVSVLQAGCFAGALAAFYLADKIGRRWSLVGAAAMTLSGVIMQAAASGHLESMYIGRFISGLGVGCASVVNPIYVSENAPRAIRGLLTSCYQLFIYITPLAIQGLPALLLFSLMLISNESPRYLARMDRWEEAKAVLRRVRNLPETHPYLQDEYREIQEQLEHERRVMGDATMWILIKEMAQSASNRKRAILSVTLMICQQMTGTNAINTYAPQIFKNLGVDGRSNSLLSTGVYGIVKVLSCLAFLLFMADSLGRRRSLLVSSVGQAFCMFYIGLYVRISPPVDKAPVPPAGYFALVCIFVFAAFFQFGWGPACWIYVAEIPTARLRPLNVALAAATQWLFNFVVARAVPNMLVTVGAHGYGTYLIFGSFCVCMFIFVWFFIPETKGKRAPSLQLVNTCQLTLYASTGVSLEHMDELFGGSKRTLTGAPTADLDNKSYEANVEVTEDKARRQSSQERYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1Z6</accession>
    <name>A0ABR1V1Z6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">D-lactate dehydrogenase (Cytochrome)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011950</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661957.1">
        <property type="nucleotide sequence ID" value="XM_066816265.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049325"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF116">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE (CYTOCHROME) (AFU_ORTHOLOGUE AFUA_7G02560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="138"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="570" mass="62156" checksum="78F65DE5E85C4177" modified="2025-10-08" version="1">MLRSFGAATSTSSPARAAAAAARSRCPNSLLARSSLRCYATEKEGSNGPSFKGQMLEMFVAGVAGAYWMGTLSPQDPDPHSTAPLSQARPLRHNLGKANLEAAWTDFADIVGKENISTIDHDLHTHSISDWSSYRAHDSERPFAVVYPATTDEVSRIMKVCHSRKIPVVGYSGGTSLEGHFTPTRGGISVDFSRMDKVISLHKDDLDVVVQPAVGWELLNEQLAQDNLFFPPDPGPGAMIGGMIGTGCSGTNAYRYGTMREWVLSLTVVLADGTVIKTRQRPRKSSAGYDLTKLFIGSEGTLGLVTEATLKITVKPQSTSVAVCSFGTIRQAADCVARVVGDGVPVAAVEILDDEQMKCINHAGMTKKVWKESPTLFFKFSGTERGVKEQIELVQKMARSTGSQSFEFAKTEEEKAELWSARKEALWSTQAMAKEGDRVWTGDVAVPMSRLPELIELTKDDIKRSGMYGTIVGHVGDGNFHIILLSNDQQRLDAEDLVHRMVKKAVEMEGTVTGEHGVGLVKRDYLPHELGDTTVDTMRKLKLALDPLCLLNCDKVIRIQKPKAGEVAEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V226</accession>
    <name>A0ABR1V226_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011975</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661982.1">
        <property type="nucleotide sequence ID" value="XM_066816290.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049350"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="326"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="865"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="961"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1013" mass="113900" checksum="721C6680402C7CDF" modified="2025-10-08" version="1">MSPPRKRAREDSSDSDDEQLEVIHPEDVTIAIFCALAYESVAVKYTLDEELECPSKTPGRGSYIYSLGRIKEHNIVIARPVDMGPVNAAQCAATVRSDISFEKQVAQQFTNVRLALLVGIGAGIPSDKVDIRLGDVAISVPRDNHPGVVQHDFGKILISAIGALEEDEMMHKRPIKKILRRLAKEDMFARPTNGDILGLILSGGGVIKNPEDRERLRRGYQDAICFEMEAAGIMNEIPCLDGWHYYAAATAASYCKAVLLKVPGSEISETTPMKDIMNKVTESLHNIDTKVEELKQDIGLKNIRSWLSAPDPAANFNKAREQHQEGTGEWLIQDERYSTWKQEQNSFLWLSGIPGCGKTVLSSYVVADLTQNSAISRSLLYFYFDFNDEEKQSHDRALRSLITQLYEKRQDLREAVDTLHSTCYQGGQQPSVDSLRMLFQRLLWKASEIWIALDALDECPIRNGLLLWIDGLREAGMSIHILVTSRPEQDIKAAFENFCSENQIIYMQTDMVKDDINAYIRTRTRKMDRWKNLPEVQREIENALVSRADGMFRWAACQFEILNDCLDRPSIRRELSNLPGTLHETYTRILLSIDKKYQHHTRRLLQFLLYSKRPLQLEEAVDALAVDIAAPRGSRFDPSNRMPLPEEILRCCSGLVVLVKGRVREARMNIPWNTGTDMHTPWDTETGMHIRLAHFSVREYLMSNQFHSLHPAIAECLNDTIARTEIVKVCLSYLLSTTRESNQRLSVQDRGTNPHYAVPRDYHLAYYAARYWAEHAKAIELSQSTALQAVVEFLSLQETPSLSYMFYAPDHSIQSPDGTAQRVVSYPSADPRRISALYYASCTGLVHSATQLLQKGAALETKCGEFGTALHSAALYGETLFVEKLLKNGAPIDARSQMFGTALQAVAGFGEESMVKLLLENGAAIDDWSEICGTALEFASGEGRVSNVKLLLEMGAQIGYALHAAALSGHKDIIRLLLNKGAKLDMRDDYGFMPLRWAEIKCQSIEVMELLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V292</accession>
    <name>A0ABR1V292_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enhancer of polycomb-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012058</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the enhancer of polycomb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662065.1">
        <property type="nucleotide sequence ID" value="XM_066816373.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049433"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024943">
        <property type="entry name" value="Enhancer_polycomb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14898">
        <property type="entry name" value="ENHANCER OF POLYCOMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Enhancer of polycomb-like N-terminal" evidence="9">
        <location>
            <begin position="10"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="382"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="540"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="559"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8065311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="588" mass="66735" checksum="711997227E5C00CC" modified="2025-10-08" version="1">MSSSRAMRIKKLSPKTILTVLLEGQIDASEYDSLTTEAKIATGVDAGEEDEIHLQAALKGAGQSTDNEIPVPPPQVSEEVKYEDLYSRPFVEPRGYIKSSDTVEETLSCLYDMTTEDDEFLKNYNQKRSSKLSEDDFERIMELFERTTSEQAPFAAVDNTTVSYEVMASQMAHSPISKLKTHAQAVYDHWKARRQSDGNRSLHPSLKFETPGQQDHDDMDPYVCFRRREVRQTRKTRQRDAMVADKLKKLRRELEDGRQLILMAHQRELMKREMLSTERLLFEHRAKLKEKKVRLGIKEGDEDLYNTKPVKRKAPVESQPAKTAPTQLRLAVRPEGRPAEQELVQLEDKQKERLEEFLRDIATKAETHRVWNARYVDLTEKPLSPPQEVEESSFRPAKAQFLPTPPASASESMELDDEPTEAAALAAKAPSTPFLFRGLSPEAEQPMPGYRRRIGRNGRLWIDRRNVGRLASPPSDSEDIFRNDRFAYDEDDSDDEQPVYHMDAFDTRPMKFRAGIPLNIMRSYRPGQDGSLAAQTTPNARAALPAPQPGSTPVAGHGQLQVQQSPSQQASKQQAQLPPIPQQSQHTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V451</accession>
    <name>A0ABR1V451_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ccr4-not transcription complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_012713</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662719.1">
        <property type="nucleotide sequence ID" value="XM_066817027.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050087"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20710">
        <property type="entry name" value="NOT1_connector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055454">
        <property type="entry name" value="CNOT1-like_NOT1_connector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25097">
        <property type="entry name" value="ARM_Cnot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="11">
        <location>
            <begin position="526"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="10">
        <location>
            <begin position="710"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="9">
        <location>
            <begin position="923"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="8">
        <location>
            <begin position="1204"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1-like NOT1 connector" evidence="12">
        <location>
            <begin position="1507"/>
            <end position="1639"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="7">
        <location>
            <begin position="1850"/>
            <end position="2194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8065966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2202" mass="246093" checksum="7CACCDCF767031A4" modified="2025-10-08" version="1">MVPPPPSSQSQPRSGTFTPAPSNHPIQTGGFGHSPHPSQGGNLSAGASPSTSSPTTGNNSLTKIVIAQVFLLLTTLKDDKDRAKWDLQRDQLKKLINDNGMEVFSKTFTRLVTQNAGTIFSGASNRPSSANYQILADEMTKIATDINQAPKIAESIETGTEDTFRDFDLSTFMEHFKLDALEKTILALAFKLGSRSDLKTKADAILSTNFPTFVNIISRPDVHPDLATDFIAHIVDRYIQGHPPNFNAAAKSELSHKVKSRWSGPDRAPPMEVLASLDLIRVLGEKPPNALALYIQRTGADFTRDEEACLGYLQNRPANIQLSEEQVSSALTYTTTSLTPRHDPSVLVAALRSVLPTTFSWQDVVSYFDQRDVRVSKQQFLRLYNALLPVAQSPAANAPKFDVQFLWGGAHWENPETQLSFICAFASLRPEELDASTIPGLVPTFKLEDYDNSPADVQERAAEAVRHPLVSVSALSAIFSVALHSIHASQSIEAKRLFQEVVVPNLDIFIVSAFGVPKPWPAMAVDTLVSLFEQFLHSRSPHGTFVMDSIWRKDRDWVKQKLVDTHALKPMDLPVIFEHVIKHNWLDELVNLPNGFGFDLAALAHAEGYLDLSQWARNNADRGPEISLSLLQFLMIKGTMELAYQRPPEGQQPQKNSTTLQVKTVAALLQIVEDFMPKVPMQNLITVQRHCIIVYPRLINFGEGYDDIIELNSRAGNALPQQANARMEEHYKTMYGNEVQVKEIVETLKRYKHSRDPLDQDVFACMIHGLFDEYSHYVDYPLEALATTAVLFGGIISHKLISDLPLKIGLGMILEAVKDHMPDESMYKFGLQALMQLFSRFREWPGFCKQLLQIPGLQGTEAWKKAGEVVREHEEEIANGQNGTSDVSGEPIANGVIDDGSAVGSNASPFASVNVDPAMNGLFEDPSEEIQDKIQFGLNNLTPAKLQTIFKEIQERLEERHHQWFASHLVEERAKMQPNYHEVYLDFVRLFQDKGLSAEVLRQTYISTARMLNSEGTMQNSTERTHLKHLGAWLGLLTIARDQPIKHRNIAFKQLLIEAHDTKRLIVAIPFVCKVLIQGARSTVYRPPNPWLMDILHLLIELYHHAELKLNLKFEIEVLCKDLNLDHKSIEPSQELLNRAPVEDVGDMALPDVLDAVDTMSFNGIGNTVSTGLSPHPMPPPTIPDLGAQVQVPPVSEMVVTTQKLHEIVRTALSRALHDIIQPVVDRSVTIAAISTQQMIHKDFQTEPDENRLRTSAITMVKATAGSLALVTSKEPLRANITNYLRQLSSDVPQGLPEGTIIMCVNLNLDLACTVIEKAAEERAVPEIEELLESELEVRRHHRRTRPNEPYVDPALNRWAMTIPNPYKLSPNMSGLNPEQMAIYEEFARQPRTAAPSGSQAHAASASDATRTIANEVLQEQFAAVPNLPTPAETPSLPQLQTQLPYPQVHQAMTNGRPSAHPAQMDTRVYADRVSKFLGELQRAATESREEHFLDLPRPHQVLDVVDALTQLIIRNSQSSEDFAFYAAEKICQLLFERIEQANTLFLESLVHVLELLLKISIAGSGAALMERVHSIFNQQLPENYFNLPLITALLRTDLLNLHLIDMALSKAIAKKEEGSLEFFERLLDLTLFNDRPVALFADYVRSLEGAWGWISEEPDLEVGQQLKAKLQGSGLPQPAALDDSSTSRQDQYEYLFDEWIHLSSNHSASEKLLSSFIKQLRNKGFLVSKEDFVSFVRTAFDTSIALYEQILHNGASQVDGYAAIDALVKLVATLAQDNILSVDDSFAGAKTIFETAFAVSALVLNHHHVSRGEHFSQRVFFRFHSMMLHQAAEIFGLTAPEAVVGQDGLEVHHRELILSFANILFQLNPARYPGFAYSWLDLVLHRRFLPILMGIGDKRGWLPFMKITTALIRYLGDHMKALGVPDIVKDFIRASVKFLVIIQHDYPEFLAANHVALCGCIPPHATQLRNIILFASPRQEPGDPQDVAALINDYDVAASYLRDNGLLELVEQLLQNGPSEDAIAHLTHAINKNERGSSVFGNVPVNTDIALVNAVVLYIGTFAVKRAQQGGDIFVSGAADMATLSLLVHEVNAEARYFLLSSIVDELRFPNPFTTYFTSALLELWGHDVNDPEETDIRQQLVRIILERFSGYWPQPWGLVLMTVELTKNDKYLFFDQPFIKGDREVRDKFQTIYRTLTDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4E1</accession>
    <name>A0ABR1V4E1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012809</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662815.1">
        <property type="nucleotide sequence ID" value="XM_066817123.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050183"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF3">
        <property type="entry name" value="CLC CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0868">Chloride</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="502"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="558"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="586"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="875" mass="96631" checksum="CE932D2D3C991182" modified="2025-10-08" version="1">MSEDIGPYDSVPPSQQSSQHLSIPVSPTYQRRHGVRSRRQSLSEQPDERTALLRRPSRSRIRIQSPAASPRAPFLSRNHSYAGSVKSRHHSRHGSWGQRLAHALGDSRHDSMAESKGSIFSDERVWYDQFTSTDWVHDSIADAYRVKALRARKDLWGRLIVLFDGAQGWILSAIVGFLVAVLAYCVDVAETTIFDYKDGYCTKGWYIREKANWRSWSEVLGGHPFGDRWTEFGVYLIGVVLFSVLACLLTLTTKTVVPSAYRMTTLDENLAAVNPSQQNDSDNDEDSDENVSPRHVTEEEVVPPMVYYSAAGSGVAEVRVILSGFVLHGFLGFKTLVIKSAGLVLSVASGLSLGKEGPYVHIATCIGNIACRMFSKYDRNDGKRREVLSAAAAAGVVVAFGAPLGGVLFGLEEVAYFFPAKTLFRTFFCCIIAALSLKFLNPYGTHKIVMFEVRYTAEWEYFEIVSFVLCGILGGALGALFIKASRAWAVTFRKIPIIKRYPMVEVVLVALVTALIGYWNVLTKLPVAKLLLNLAAPCDDETRDELDLCPTSIDEIPAILRTLIAALFIKSFLTTITFGIKVPAGIYVPSMVVGGLLGRIIGHVVQWIVLRFPHWALWGTCPIYADGSCIQPGVYGLIAAGSTMCGVTRLSVTLAVILFELTGSLDYVLPFSLAILVAKWTADAIEPLSIYDLLTEMNSYPFLDNKHKPIFTSDLADIVPRVRSQRVVDITNSPLVPAASLRAKLETLHRTGELDGGLPILRDGVLVGLIPAPDLEYALDQLEDESTNLCLMADVPNIDDDDDEGGRDPTDFTPYIDPAPVALDIKSPMDLVYECFVKLGLRYICVLKDGRYAGMTHKKQFVKYMRGLEEEQRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4R4</accession>
    <name>A0ABR1V4R4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012936</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662942.1">
        <property type="nucleotide sequence ID" value="XM_066817250.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050310"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF108">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="47"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="370" mass="40824" checksum="1C484AE185358C88" modified="2025-10-08" version="1">MPPGPVGAIPPPPGVTPNFENPEDILNTINLASQILSIVIMTIFLALRVYVKAKVAPPFLLDDWACCIAWVRVLSRLCFSCAPYLSLTWNGLTTVVQLLGPRRGIQHDSRNDGTLRGGYHAWDLTVQDYEGFLKARPITSASFALLLVIARVFGSFRATRISAWVIIILMLCYYIPVFIIKVQVCRPINAYWDLSIKGVDLVSQRALFVADTVMSTVSDTAVLILPIPATVSLRMQIGQKLKIWSMLGLGGLATMASIVRMVIVVKLQSSNDQSVEFVRFNLLGTAEVTIGVVCACLPALNILVARHRISSRESSEQSQSKFVEVMRSIKFLAGSKLQTAPPITPLRVTNMTRNNNNNNPNVNDNDMELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V514</accession>
    <name>A0ABR1V514_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663039.1">
        <property type="nucleotide sequence ID" value="XM_066817347.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050407"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="160" mass="18142" checksum="6A96E5BB2BDF7DAE" modified="2025-10-08" version="1">MGSKARPFQNDPGEAGGLHKFPTRPAHGENTFSSSTYGLLSNYFAIYFLEKSDESNESKESHELKGSQKVWKRYYIEVRHQIEQNDVPKGFKLQQIIKQAVGRLGIGDDHYASDFKSQLIVLEPIASKKREFIEAFTNEQGRAKPYSVKFVVKPTLSSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V520</accession>
    <name>A0ABR1V520_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662113.1">
        <property type="nucleotide sequence ID" value="XM_066816421.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049481"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="9394" checksum="72CAABC9509797FD" modified="2025-10-08" version="1">MSSSRPMQDGNGVSASATAGSTTSSTTNTAAAAAAPHSHAMRAYVTEPGSAGNRNAALHGSQPRPEAEVVKEFEMRMQMQLDDCMRKLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V553</accession>
    <name>A0ABR1V553_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013075</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663081.1">
        <property type="nucleotide sequence ID" value="XM_066817389.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050449"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF28">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="35"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="98"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="420"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="842" mass="93042" checksum="F29C7AB4A6515F6D" modified="2025-10-08" version="1" fragment="single">HDRLASPQPNSTAAKDAQAARKRRRRAPAGGAADDCFACMKRNAKCDRRRPYCSQCLEIGNECSGYKTQLTWGVGVASRGKLRGLSLPIAKAPPVAPVGKRVTPARPRANSSIVTSQWGDHEDGSSRDDVEYHHDHPGSIPPTPYAVYQEFARYSQGETAPSATSQSWGGMSFASNEHPRIQKLNTSLGHYSSIADGLASSVDSLSDVEYAISPMSHSFPREDMHFLNSPSLLYDNYNSHNSPIPRSPASAILIDQRGPTSCPGLIYAPSEPSSSLSSHQDTFESQVGASKFLAADSDTLSVHDVDNFSTSPSSTGHYWAHTSSRDEDLNIFCSEQGPLAAPFEGHSMQVTPDLIAKMPFFMDYYENTMCPSMVLIDGPNNPFRDHVLRLASSSRSLQHAICALAACNLRMKRRLSLGQHTRDSPERLSSDNHESPSDDLPLSEEYQHRNLAVHLLNQQLNDSSKSCHDSVLATILLLCHYRMVESGIAKFHTQFAGVKKILSMRNSAPYQASSDSAWMEALFTYFDAISASINDREAQLNHTFYGVPTDSHLLPPGVELFVGCDRELFKTVMKLGRLNMLSQHRPVSSPLTTATGRIGTPSASSPLTSPSHVFKNSHLGDFFTVASVAHRFDGNGFATQLDDEELISSGLCSSPSYEDHRSTFWREWKEARNALQSWDFEPHRLMASLPGSPTPSLIRDLGSLSEAFRYAALLYIERLASPNIPSSHESFRNLVSQVVYYATSLETGSSAEKFLLWPLFVAGSECVNELQQNIVRNKCREIMSRSGYMNNLSAIDVLERLWAGEYRDTESSSNNRLGQRRGPFNWTKCIGGAGVEVEWMMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5H6</accession>
    <name>A0ABR1V5H6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013196</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663202.1">
        <property type="nucleotide sequence ID" value="XM_066817510.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050570"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF130">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="330"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="428" mass="45907" checksum="F525108385DEB2F8" modified="2025-10-08" version="1">MSSPKDLEKKNEFTVSVVPLSQSQVSLSSVESGTPPAPGNAEDEAPDGGWMAWRQVIAGHFINAISCGYSATFGIYQLYYTEALNLPAAQIAWIGSFQIFLNSLVCLAGGSLSDAGYARHCVWAGSLCVLIGTFMTSIATEYYQIFLAQGVLQGLGLGLMFMPSTSVVSSYFKRKRSIALTIASAGTGTGSIVFPATVQFLIPKIGFAWAVRCSGFVAVVICVIGCILLKPRLAPRKGVAIVELKAFKEVPYVLFAVGTWFFYWALYFGFFYINSFALTLPGNVFTPYLHVFIGWIADNHLGPFNTYILSVASLAVTLFAWTGVTNLPGMYVWAVAFGITNGAAQAAYVGAIAGLTKDPKRIGVRIGMIFGIISFAVLAGPPTAGSIIDSTGGTYRWAQVWGGSVELLAVVVLCVGRWFVARDLWVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5N3</accession>
    <name>A0ABR1V5N3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitronate monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013242</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663248.1">
        <property type="nucleotide sequence ID" value="XM_066817556.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050616"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF28">
        <property type="entry name" value="DIOXYGENASE FAMILY OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="331" mass="35573" checksum="CEF014ABB577C537" modified="2025-10-08" version="1">MPFDTELTRRLGIKIPVVQGGMQHVGVAELASAVSNAGGLGILTALTQPTPEDLRKEIRRCRAMTKKDHPFGVNITLLPALNPPDYGAYAQVVIDEGINIVETAGNSPGPVIKKLKAAGVIILHKCTTIRHAQSAIKLGVDFLSIDGFECAGHVGESDITNFILLSRARQSLKVPFIASGGFADGQGLAAALCLGAEGINMGTRFMCTAEAPIHQNIKETICKAQETDTSLVMRKWTNTTRLYRNKVTEEAIKVEAAADGTTFEPMAPLMSGKRGREVFVNGDPDYGVWTAGQVIGLIHDIPTCDVLVKRIEKEAEETLKSKLSLSSRAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5S7</accession>
    <name>A0ABR1V5S7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663015.1">
        <property type="nucleotide sequence ID" value="XM_066817323.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050383"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="12"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="281" mass="31987" checksum="60602FACB8CB31BD" modified="2025-10-08" version="1">MPLDLQQSIAASIELDNFQLSYRPGDVITGNVVRIQLDQPDEVVVTLQFWARVKTRIAESQSNGPNGTNSTRYYEGESTLFNIAETLYQGRAFEGKNVWPFTVTIPDTHLPPRPAAGNTLPPSHYLRDEHLAHMRQRRKYLYVKYVMEADVRSLTKKGKSAMAVLPLNIRTPSSPTPIRDFATRAMATEETVRTLHLLPEYANESLSIRQHMRSVFKRSKIPHYSFAIVVEFPTVIQLEHPTQYRSRSGASCEPERTKRRAPWPKSRRTSTSSRAKCTCGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5T6</accession>
    <name>A0ABR1V5T6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013311</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663317.1">
        <property type="nucleotide sequence ID" value="XM_066817625.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050685"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF40">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="699"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="769" mass="86332" checksum="0F28B3C75F089489" modified="2025-10-08" version="1">MLISILPITSCIGMDKIALLFSGSSMRFKNGALESEFRMPTMDHEPGGQVIQLQQTSQTLIGKYRRNRKLQSCEPCRKSKLACDHSVPCGRCIRRRCVDKCFYHPNPLTRNRHTVSQAASATADSPSYSAGSSLGLVRSIEPPQSTKLGGPVRFVCKEAPVVHRASSAPPLHHAYDHEVVRSEKQSFLGSTSLTSMLTEDLEKLGVPSVDLQTFSAQSVAISYDRMTKGCEVLAFLRNDSMVNQFINCFYGNWEGDVAFCVQPIMKMWLMELWRFHGGVLKSQNPDKIRQLCELIWMQLSTGVNLRWDVIGLIACYVATAAAAGDTSKKLLEEYQTTREAVMCSMLDIAATCLTFCRECEILDDTFLWLTAEYYALIGFVKGEVSSAVYRAGAELASTVLAMGLHQYIRANTSVPPFLAQLRKQARMVTYSTEISVSAFLGRPPRLSYRYINLDTGYDFTSDEVLAEESEFAANVSKLLEGGYNSDGRIRPITFWKVWIPFAILREQILELALGDLPAHEVRVRADEIQQKTKEQWTKVPAIYARCRDEELLGTRANEFLLQRVLFQKAGASVEGLIKVAQQMFKDLIRMSEDPELIKISSINTNHMVAIHGLRCAAVLAIELLRQEQLPVYPKEPLLPRSQTIQDLSVFVSRLDLILKVELLQGILPMCEQGRKVLTRILDKILSPPNAADRPCQSCCHTGGHQQAHPQSELDGFQQGMVPNDESDDLGHTSFMVMDDFNFAIDAPYLGPDHDFRQWLENMDWTQTVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6M8</accession>
    <name>A0ABR1V6M8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ricin B-type lectin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663578.1">
        <property type="nucleotide sequence ID" value="XM_066817886.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050946"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046223478" evidence="3">
        <location>
            <begin position="23"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="25"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="152" mass="15778" checksum="C2F2FC70FFB3C576" modified="2025-10-08" version="1">MRIQTASLALLGAVRAPFGCDAQTVSVTIANGTLVGLEDGASGVQRFLGIPYAQSPVGDLRLRQAKPLASSFGTLPADAFGSSCYGSRAQPNASEDCLTLNIWRPDGKKAQGNGSLPVLVWLYGGGLTAGYTVCKTSGRLPHLSNLMTDPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6N7</accession>
    <name>A0ABR1V6N7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663620.1">
        <property type="nucleotide sequence ID" value="XM_066817928.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050988"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="121" mass="14300" checksum="E6EA5D90313159FA" modified="2025-10-08" version="1">MAEEIRDTIYDDSFTVDQAFDLGGQASNYKNYQDVRLHINKFGLNRQIWHEVWEHLIENNLWIRVNIGRHSPFTDFFEKTFHGDGPFEHAQSVTFAYYPLTYGYFLDELSEYSHGNQAVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7A6</accession>
    <name>A0ABR1V7A6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013821</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAP domain-containing ribonucleoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663827.1">
        <property type="nucleotide sequence ID" value="XM_066818135.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051195"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052240">
        <property type="entry name" value="SAP_domain_ribonucleoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040746">
        <property type="entry name" value="THO1_MOS11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551:SF1">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18592">
        <property type="entry name" value="Tho1_MOS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="4">
        <location>
            <begin position="4"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="258"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00046328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8067074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="277" mass="30465" checksum="06C8BB7D39A77947" modified="2025-10-08" version="1">MADYNTYKVPELKKLLQEKSLPVAGNKADLVARLQKYDEENAPAKPAAAAPVAPAATTTSTAEDEIDWDDDEPAAPAPAAQRRLRPPRRRRRRKQQQQRRLRGNATAEAAPEAEEEKKEEEPKPDFSAHLAASAAEEEIKKRAERAKRFGIIEETSEEEKKRLERAKRFGAPDTTAVVKGLDEALPERRPKRGRDEGAEAGGRGPKRSNNDSRRGGGGGGRGGGDRGRGGRRGDRRGGNDRDRKPNGGGVSKPSRVLDNPEEKRKAEERAKRFASNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7F6</accession>
    <name>A0ABR1V7F6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA/RNA-binding protein Kin17 WH-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663877.1">
        <property type="nucleotide sequence ID" value="XM_066818185.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051245"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2030">
        <property type="entry name" value="DNA/RNA-binding protein Kin17, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056767">
        <property type="entry name" value="C2H2-Znf_KIN17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019447">
        <property type="entry name" value="DNA/RNA-bd_Kin17_WH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037321">
        <property type="entry name" value="KIN17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038254">
        <property type="entry name" value="KIN17_WH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805:SF0">
        <property type="entry name" value="DNA_RNA-BINDING PROTEIN KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805">
        <property type="entry name" value="KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25095">
        <property type="entry name" value="C2H2-zf_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10357">
        <property type="entry name" value="WH_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01253">
        <property type="entry name" value="Kin17_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA-binding protein Kin17 WH-like" evidence="2">
        <location>
            <begin position="52"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="352" mass="39235" checksum="33A09976AEB941AB" modified="2025-10-08" version="1">MGKAEVGSAKHLSNQMRRKGLQRLRWYCQVCEKQCFDDNGFKMHTQSESHVRQMLVVGEDSKKFINDYSRQFQRDFLQLLRTSHGEKAVQINQFYQSYIANKEHVHMNATKWPSLTEFAKHLGREGICRVEEKEDGKGIFVAWIDDSPEAMRRREAIKKKEMQDKGDEEREQRMIKEQIKRANKEAAARGGVDPEAAAADEPAEGRVLKRDEGEKIKLSFGAKPAAPAEPAKEPSPEKGLSGSPDEVSKPTDAGPAEPNAEKKSTPEAPAPATAAAAPVSLKMAAKPQPKNVFAAAKKNALSGGSKKPSPFQQPKKMSEAERIMKEEMEKNNKKRPGSGFGGFAFNKKQRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7V0</accession>
    <name>A0ABR1V7V0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664024.1">
        <property type="nucleotide sequence ID" value="XM_066818332.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051392"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="700" mass="69654" checksum="600617145F6709AF" modified="2025-10-08" version="1">MSSRQTRHPQPTEGERGTRRKLVTAICLLSLSLSTLLLLRTKWQLADYETEGGHPSPKSWIPSTLMKQSTADAIASDELIRRNFLAFVEFGADTSDEWASRSGSESLREASQVLRTMRDELSMNARSQSSSSFGEIVQLGKRSEPKKNAKRGLLEDIADKGIQAVINAAGGSLTGIGAAAGIGVGQGTVQGLKLKTADQAKAIAAQVMKESGDETSSLSPVVVSVGSNAAAVITRSIDLGNFTNNPMLAPAARGLAVGLGNGAVNGLGLAMRPPPPNSSNLADVAGNLGYGLSDTVSSAINIQQLLNSSGAGAIKQQLPAGVLGLAQGVGTGAVSGLNISQVPPPSEANSDVPSLLRVFGYGLTNSVTSSIPLQNLVALVPGGAGGITQQLPSAVLNLAQGIGNGAVTGLKIANVPPPPENTSVPAIAGTFGYGISNSVTSNINVKSLLASAAGSGIGSGITAQAPQIALGLGQGLGNGAVTGLKLNMVAPPNGSSPADIAGSLGYGLTQSVTSNLNLASLGSAINPQLLLQNLPEAASGLGRGLGAGVPIGLGLMPDPGPVMGPNGTRSDVGAITEDFGTGLTAGFLSNGTLSKVLAMTAGSGLLPKVDPAAAANGLGRGLAQGVTDAVTAMGGFNSLLNGNATVPTGPVPSTPVQFNDSLGGAAIGLGQGLGTGGALALQKGPDGRRPRGPIPGPQPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7V4</accession>
    <name>A0ABR1V7V4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pinin/SDK/MemA protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_012901</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pinin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662907.1">
        <property type="nucleotide sequence ID" value="XM_066817215.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050275"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039853">
        <property type="entry name" value="Pinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006786">
        <property type="entry name" value="Pinin_SDK_MemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707:SF0">
        <property type="entry name" value="PININ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707">
        <property type="entry name" value="PINN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04696">
        <property type="entry name" value="Pinin_SDK_memA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Pinin/SDK/MemA protein" evidence="9">
        <location>
            <begin position="90"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="213"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="270"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="324" mass="36614" checksum="DA4AC00552460006" modified="2025-10-08" version="1">MSTDDDSLRNADGATTITDAKMEDSSNTQKRKAQSPSPSEATTYQSPKRTRREDPNAADRGSRRGSTATRSPTVPRQISPTDRRLSTSMEEKKRGKRLFGGLMNTLSQTTTNSQQKRRQEIERRQQEKATQQRAEDSKHREAKLAKVKEVRQREQINFEEQVMKTRHSHLVSMARYLRTKTEPHIYYLPWDLTQRQEDLIKAQVQDAEDLVNQETREFKQRREKRHGDSGIAEQKHPTPPGDEMITEETSQPPPSSDQPQEDQQQQQSTAGSKSNDSDPNSPAQPDSTNDRASAQASKAGGAHVKEADEAGDVMVVEGEDTVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V857</accession>
    <name>A0ABR1V857_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NadR/Ttd14 AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664115.1">
        <property type="nucleotide sequence ID" value="XM_066818423.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051483"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NadR/Ttd14 AAA" evidence="1">
        <location>
            <begin position="8"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="214" mass="23744" checksum="ABA8A71F1CCAC68B" modified="2025-10-08" version="1">MPTTPRNIYIIGAQSTGKSTLVDALEAHFRQNTSSSLPAPTVIREVARAVLRDHNFTAQDIRDSPTRALELQRLILAAQAKAEGEVKNKASLTPSTPSSWLISDRSAIDPVVYAWMYVGPEAAKALMESTEWRGMHDRMAGSLVVVCEAGVEWLTDDGVRLMPTGKSEWARTHEVFCQVLEEASMRYIVLPCNLGQTEERLDFVLRNYKSPGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V898</accession>
    <name>A0ABR1V898_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cullin-associated nedd8-dissociated protein 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014135</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAND family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664141.1">
        <property type="nucleotide sequence ID" value="XM_066818449.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051509"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039852">
        <property type="entry name" value="CAND1/CAND2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013932">
        <property type="entry name" value="TATA-bd_TIP120"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12696">
        <property type="entry name" value="TIP120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08623">
        <property type="entry name" value="TIP120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25782">
        <property type="entry name" value="TPR_CAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="TATA-binding protein interacting (TIP20)" evidence="5">
        <location>
            <begin position="1136"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="350"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="351"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8067388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1335" mass="145659" checksum="F88A6647EBC7B2C3" modified="2025-10-08" version="1">MATSINNPNPSTINTLLGKLTDPDPDFRFMSLDDLNQILTKHKTDFLNHDYGLASRTVDAVVKALDDQNGEVQNLAIKCLGPLVSRVPIAAVGPTLEKLTSIKMQNAVDNSLPSLALRNVISALPKPVRGVAPSRDVMETYNIISRVLIPRILGVSVNAASTRQSAAETYGLLDEKSEPTSEAVDVLIEVVRCFGPLLQVLEVEKLQEVVVQVLERKTTSSPVKKRAVVALAILAPYLSDDVLTSLITKMDASLKQPKLSPVMRRLYITIMGSLARSIPPPVLSQTELQAQLDAVSEGDDRAMVEFNEVREAALIALEAFLSSCGTKMRPYTEEVISSCLRYLKYDPNYATDDDEDMDEEEEGDDEGGLSDDDDFEDDGGFDDDDDDASWKVRRCAAKALYTLISTRSSDLLGKGTLYSEVAAPLIKRFDEREESVRLEVISTMSLLIRKTGEGIIRTVNADEELLQSLPESRKRRRQDSGGFAYMNKAPYGATGLTSPMREEVPPTGPRADLSNLTPQLVKVATKLLKGKQIPTKQAIVNLLDDLISVQHGGLSTYFDQVMQPIIDATKVTTGSSVSTSVALSGGAASATMTTLRVAVLVFISDIAKTHSSNLFQAYLSKIVAGVVAAVQDRFYKVSSEAIRTAEELVKAITPPRARMTSQKYKPDLETLYDIIIDRTAANDADVEVRQKAIQALGTLLSRTSSNDGQSLLDAEKRQAALDLLLDRLRNETTRLYAVRAIDKVAAHTTGGTLQPSWIQPVALELCGQFRKANRALRGASIQALQHLVTSPTSKGNLEPSTVDGIVAAILPVITANDSHLLGPALLVLAQLQQEDSNLISTPGLIPAICELLKHTITGTALEALISLVISVGQVGMAKPLMSGVLQVGVGGDPAVVGKVAGALFVASEGNAGVEIGSFVRELESANQASDNARQSLALAILGEIGLRMGPKSEMKPDLFLKQFHEEPDKVSMSAAVALGRAGAGNVPEFLPVILQAVQAKGAHQYLLLQAIREILQQVVHSSIDVGKYHTTIWDLLLSVSKAEDNKAICAECIGRLAIIEPKTYIPKLQGLLQTKDAAVAIQALRYTLPDSDETFDAMLKPVLVDMLLTVLKSEDMEIRRIGMTTLNSATHNKPDLILPHLGELVPFVMVESIIKPELIREVQMGPFKHQVDDGLEVRKSAYETLYALMENAFSRISSLEFYDRVIAGLRDENDIRSLCNLMLSKLIVIDPEETTRRLDTIAECYRKTLSTKLKEGSVKQEVEKQEEANKSVLRVTLLLADRTKTTLPTANAAGGAPSQQTQQVSNPVWQQYWEWVNKDFERQIKVLRDESKELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8T0</accession>
    <name>A0ABR1V8T0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664050.1">
        <property type="nucleotide sequence ID" value="XM_066818358.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051418"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045869963" evidence="1">
        <location>
            <begin position="22"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="21162" checksum="9D06BA63045837F8" modified="2025-10-08" version="1">MPNLVNAAVCCLVAALEAGVALDLLDIEVLAVLSLPGALAAITEGNIHIGAADEGDDLVLGVDQLAASLLSARTDIERDLVVGALGPDGRLGVLLADPGLGSELRGPAQGNAERTVGARLDLHIPLGGRGYELGAALHLADFRGALERPLALAGVAEGGVDVGAAGDGDGPAAGVEEAAAQVLALVVLEVVRRELDRGEVGPGPDGPLLLVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH01</accession>
    <name>A0ABR1VH01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664321.1">
        <property type="nucleotide sequence ID" value="XM_066815031.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048091"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="157" mass="16714" checksum="FC522DE4B270345B" modified="2025-10-08" version="1">MAGQNKMTGTGEFTPRETQLAILAWGYMETEPKIDLEKFHKAAGFLNVNSCRVNWGAVKKKLMAQAAANDGAGSDDAGPATPTAPNPKGKRASAKTATASTGSKRKARTMKSAARAQDDVSDGDDLDIIETPSKKAKTTGIKKEDQVKDEEDSLDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH08</accession>
    <name>A0ABR1VH08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664334.1">
        <property type="nucleotide sequence ID" value="XM_066815044.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048104"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="126" mass="13668" checksum="46702359F0854C9C" modified="2025-10-08" version="1">MTFRVVLSEPTVKPEPEPGLNASQFYAINGHIFKDFRIGDDMTLSRKAVKESSAIFKKKDVPLAYKCSNIRDRGSPEHAFGNLIALHCRGCNWGICQSKGNEGLALRVGSFPPTVVKCGATLAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHS8</accession>
    <name>A0ABR1VHS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011001</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664606.1">
        <property type="nucleotide sequence ID" value="XM_066815316.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048376"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="612"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="647"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="722"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="730"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8070798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="768" mass="86518" checksum="CDA412A2D95BF865" modified="2025-10-08" version="1">MPSVILCEKAAMRYHCAKKSIGPDLCANWKHMDRGTEGKPSGTQDIQPEATSAKTDPDKPPNGLQGPSSKPAPISPDSSLNDAQRQLANSLAASVQNTVEKEMNELLKQLLRNSERQITLLKASLSDAWRDSGQTAHLRAALDLEEPWSLSDEALVDIEVGAKEQELHKTDSNYPLQSLCYDFGSVRTDRIAMLIILSVWGFPEFIHENLASTGVDPEVIRASLRASNSEETDYFFFMKLGKLSNELPAKRNMDIWLKRGDTVVKMKQRYAGVKSDRLIANGLLAKLMIQEWRRSISDDWIDEPLKYYWGLEPSVTADKHEYGSWSFVRAPSIGMDDTFMSLANMANAVSQSAVIAPIGLRSEVAELAIVFLLSFTGPWKTIRPRVGLNAAETNRDLATGKPVWSYFMSNASLWTETMHLTIRVFSPIEEEGTWGGNDEGGIKLSRVVGTFERKPLKGLLEDVFDSKKRSSLMFETSSDSKFQSSDRYFFVTELLRISTEWIKETGHDLELPQSRINAIMTRLMEDGTDYYGGEPPNAASWKACSDVMSHNWTIVFREYNKYEKDLLDRIERKTQEVKTLRDGVSDFSPGRRERLHATSVREATKGTNINEYILVFTVMTITYLPLGFVSTLYGMDMFDFEIPGQTTSFAITTVVVSLATYLAAFGLLYGVRQRRKKGSFGELLSGPRGWIRPAVDRTRRVLKVGDSQPEIEVRIDEELPPELPEVYGSKGKDLDDYDRDQPSHLNVISDWVTRQRRRQEADGSVETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ01</accession>
    <name>A0ABR1VJ01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_011418</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665023.1">
        <property type="nucleotide sequence ID" value="XM_066815733.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048793"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046144776" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="18"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="57"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8071215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="524" mass="57647" checksum="C372B287F9FAC0C7" modified="2025-10-08" version="1">MRSLIFVLGGLLSIAQGATNTTWANVTECLRKNEVPIDEHGSIDWIRDSAAYNVRLPIFTPAAIVVPTTITQIQKAVICGNQTNVKVSAKAGGHSYTGGGFGSENGHLIVQLDRMYNVTLDKTTNITTVQPGARLGHMATELYNLGKRAISHGTCPRQVECVLVGASGHLTSGGYGMSSHTHGLALDWVEGAAVILANGSIVETNATYNEDLFWAIRGAGPNFGIVASWRLQTFEAPVNLTWFRIALDWNRDTAARYLGDVETYINTEMPAELNFHIADYEKGHPIAEGLYYGNDEQMKSAIGPLLKASNGNLTNHKQVDWIDAMKHYSVDNTFNTTGVVIDYIEPGPPDNFFAKSLTFNSLKGDAAKAFVDYWYGTALQVDRRWFFQIDAAGGANSAYSQPPFDSRATSSYAHRDQTFIIQFYDAVPASHNNESYPANGLSFLSGWVDGVTAALDKGNNTNWGAYANYPDPTLSRGEAQKRYYGASLEQLRKYKQKYDPGELFKFPQSIEPLLQQPSDALRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ97</accession>
    <name>A0ABR1VJ97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MFS maltose permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664765.1">
        <property type="nucleotide sequence ID" value="XM_066815475.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048535"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="571" mass="63467" checksum="4B32C3626AD41E9D" modified="2025-10-08" version="1">MQSRLAARRLLLARPLPAKAPSVARLFMRQSHLTSLSRPQLPFLSNPLARNKQWRYLTTERKRWLVYEVFLGAKYIVYTWAIVACLLVGYWSVQQEWLERRYPSPHEWSFITRLRFRLLKWGPDRTDTPQPNWVQIGNLAKNVLERLEDPATDGADLQELLDGGIWIDGIGNAGKDITAKSEPWRRGYYEVLMLCAKAAEKLDNHLVDTTRHIVFPAEQVFGPSNPNPKPIPPGSPSAPHEKDCEVAYEAPETFYMKILTTKGFTNKQKLDAALDYGAWLDFKGLPDASAKMYEWALQLASENTLPTALPYNPHTFVLQDTRQPSANILTTLTAIAAHKARNDDVSSALPILISILRARRSLPAAGTSSSVPLKGDGQTASPWTVSNVLGVAKRLAAPPAYPPPPPDGETHPLRDAKELCEEAGLNLYIGEIIYTSKDGSSGRVDGLAWTREAVDLAEEQLHKLGAESRDEAAKKTCKECLHTGLENWATMVGRLAKEERGRQQKVGAGATATKSGGGWFGSLWGEGQARPDEVGRWTAEEKVVKERTRRAQEILDVLEAPKVGLGSLFWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VL89</accession>
    <name>A0ABR1VL89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664431.1">
        <property type="nucleotide sequence ID" value="XM_066815141.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048201"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="362" mass="40750" checksum="99BFDDB9867AD601" modified="2025-10-08" version="1">MAHQAHALPWNTLAKHYKYKMSYTHEPQRKDIFPADKGSDSKEIDYFCRALAARVQEFAATERAKYRPQPELRARAGTWTKSAMTDAVGPSARPAAAGGRQTTAEETRMVYPNEMQFRYFEEGHDEGADLPTRVTAMHNKDLRPLSQWTDCAHGSRIGHADAIKIMLMEAAGVAPAICASAPDTDKDTSALQTEIMESLLLIANKPEAKLLTFITARHGHRHGVCRAAEEAVRVYLYLNLLVVMQEQGSDAVDFARTDAGEEIKERRNYMDLKSYSRLLSSVAGEYDGDAQNLVHWDYFFTRGEDDWNRSEVKDVLADMEGLKEYLKGVWRILVVYDLFVREAGGDPELAEMCKTTLDISFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLR1</accession>
    <name>A0ABR1VLR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mitochondrial inner-membrane-bound regulator-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011067</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664672.1">
        <property type="nucleotide sequence ID" value="XM_066815382.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048442"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048401">
        <property type="entry name" value="SLS1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032741">
        <property type="entry name" value="Sls1_KH-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048748">
        <property type="entry name" value="SLS1_KH2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14611">
        <property type="entry name" value="KH_SLS1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20777">
        <property type="entry name" value="KH_SLS1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20778">
        <property type="entry name" value="SLS1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLS1 first KH" evidence="2">
        <location>
            <begin position="325"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 second KH" evidence="3">
        <location>
            <begin position="409"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 C-terminal" evidence="4">
        <location>
            <begin position="501"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="884"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8070864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="931" mass="104285" checksum="EF4EF45279EE45AD" modified="2025-10-08" version="1">MISRKISSGAICLGCRLRLLSQTTRPRYPHALTRYTAAVASRRQTLRWFTSDQPADRPTEHGQNHDEENQSPDETELATRTQNKSFYKPDFFATDEPGNDYENRRSRRKPEGGAFIFKRLNTSKIHLSRNRLLTEASENLGSDMLGKPAYAIVMKDQGLYRQKKRSAVPVDTDAATTEEQSSQLEIQALLEHQDEPVTPEELVDYIDSFKAALKEATEAGAGTEEVSENEHDEIEPESQAADSDEASPQGEVDSSAPVTTYPWIREISPWVRLNSEEVAAGGLPEDTDRHLHGYVSETAAAKEKLAVRIMRECWGLHIEELMGGLGQVDVVVRKLEFTMLMRGTRRFLKLLNDRFLDRGESMDIFMKKATIRFVSTRPKAETLIHELNVILQNITTRHFPVSLVAGPHDLIDEVLLEEVGRISNTYIKQSHSTKRIAVTWLEGRGRKTNQSEYDVEDLRHVVFRLLMSALNPESALLKLYAPEEATPYLEGSLLVDEYNREKWSWKDKLGRWARYIIPPGTEDAAQHFLDEQDPLPNPPVQLLLAETPVSLPMEEDAALQITRDVLDGAKVYNKSTIADLEKAKIEVQTPSERHPHQPVRWSPEVHTATSAVFGHVLLDAMGLPAKALIPEHEQTRADLSSYSRIFSPIVPHPMQLAAIHGGNQPDDQGNKPSFSVEHTILIRFLPAPSPNPAEPNYPGPPLELRLALTDSDDPVITGVHSLRAIVETHLHDVMLPSSPVDVRVQQQRVATLQGHPEDLATWQPLQAFLDRARLDISDGKLEMPAQQRFQIPARLFYNAHYPPISTTLSAKAAAKEHAKREKMGKKLQARMPAKKNEPISIPYAFMGLELHRAISVPYEGHTLTYTSIEAGQGGGRRAELALSPKPLPSDVSSAEAGEALEKQEEQPPMSDFLKLVYKTAQTAKFWSGFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VT59</accession>
    <name>A0ABR1VT59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665400.1">
        <property type="nucleotide sequence ID" value="XM_066813438.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046498"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="30991" checksum="10F6483A1305B01E" modified="2025-10-08" version="1">MEHNNQQYQYQQVLPQHAGNDATTEKMPADEMQQHGAYGHGQPGVLQHHQQQYHQHQQYAGAADPHAAGHNQYPPAAGGYATTQQVPSHPAKGSPKGTILGMKRGLFVALMLLLLLLIGLVIGLAAGLGVSQSNLHAKESELAAAKSSASPTVFVTVSPAATASGAKPTTTSSHPTGAADKYSCLSNGATANNTQYTSTAAKSNNKFTVYCGIDFGDQEGAKNLEAVNATSMPDCMDACARARDCQGAGWGTLGEANDDPHMCYMKTNLSKSHGADKGWTFAVLTSVPITVSSPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU41</accession>
    <name>A0ABR1VU41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Endoplasmic reticulum transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_009438</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the BCAP29/BCAP31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665715.1">
        <property type="nucleotide sequence ID" value="XM_066813753.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046813"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008417">
        <property type="entry name" value="BAP29/BAP31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040463">
        <property type="entry name" value="BAP29/BAP31_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041672">
        <property type="entry name" value="Bap31/Bap29_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701">
        <property type="entry name" value="BCR-ASSOCIATED PROTEIN, BAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701:SF20">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05529">
        <property type="entry name" value="Bap31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18035">
        <property type="entry name" value="Bap31_Bap29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="BAP29/BAP31 transmembrane" evidence="13">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Bap31/Bap29 cytoplasmic coiled-coil" evidence="14">
        <location>
            <begin position="161"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="163"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8074775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="230" mass="26376" checksum="899BC54B140F6AC1" modified="2025-10-08" version="1">MTLYYSLVFMLLVAEMALFMGLIVPMPFSVRRKIFTFISESKLVAKLQYGLKITFIFILILFIDSVNRVYRVQIELAAATDSNKGSAAIMGHERLEVQARKFYSQRNMYLCGFTLFLSLILNRTYMMILDVLRLEEKLKQYEGTDSNTKQSSKLAQAGEAGEIGTLKRQLEAKDRDIATLKKQSEGLQKEYHELTEKYGATQPRLVRVYDYTLAWDRVDVTYVTEGGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUZ9</accession>
    <name>A0ABR1VUZ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666015.1">
        <property type="nucleotide sequence ID" value="XM_066814053.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047113"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="152" mass="17166" checksum="ED96C7592EDFBEEC" modified="2025-10-08" version="1">MNTSPSQPECQANRKRPRQEDDVNARRVKRRKGSTSSDHSEAKSRRTDRKQGKAEAQVDESSSSSSQCQLPISPPPSPKIRPLLDFQYPVHDITPASLRDYMMSGSYRDCFLGEEVNNIILNEYRAAESQQSKTTQPSRENLLAMRVLSGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVE0</accession>
    <name>A0ABR1VVE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666144.1">
        <property type="nucleotide sequence ID" value="XM_066814182.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047242"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF4">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="247"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="422" mass="46018" checksum="D533705F4BE963A5" modified="2025-10-08" version="1">MDKHGYPSPPSTPSTTSSSSRLSLSEFQLPFPELTPFDSISQRGGEQDDTTQSHELPTPGNSDHGHTNLIRKTTSLFSSQSSRSRSSDSLILNRMTATLSFDGLPFIKRCERIGHLPHFKLTLNADRKLEEQQMKVSFVPLPDDRNKAQGLAREVPGGKRGATSSGANADGASDSGIGESTGGPDGQSPPASGDSGVSTGEIEVALHVVEIFRPHGAPRPHPGRPVERDDDEYPPGPPSSPEHYRNKFFEIRKSPLAGYGAFARKDLRWGQQILVEPELFHADHVTLYDEFDKLTVGSQQAFKRMAAHCPYAGFDAVTSIFRTNSFNVGGGQAGIFLVAARFNHSCSPRNTVSYKFDEDGDHGKRRIIFTMTQDVAAGTELTITYASCREELYSQWGFVCGCGCVPLSDEEVARLAPGTNWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVS7</accession>
    <name>A0ABR1VVS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010018</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666295.1">
        <property type="nucleotide sequence ID" value="XM_066814333.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047393"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="288"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="589" mass="65517" checksum="8B2FDA375E9183C7" modified="2025-10-08" version="1">MRHLLHPATRRPISTATATCVDSDEGSDSDNEDDDDDHEWGFYLPRIPAPRPHLQNARPDGSTPFSLIELIGAVQAGEQVERIRNYLTFHSRGDGSELKRLINGTILGFPAFFYVVETRCPDLIRLWATYGGDAHATYGPLRVPLLGYAIAIGGSFQHDTRQAVVALLALGASADVIPRAFYDPLERDLPDGGPPEKELSDLEDTNKRWCTPHALTKLTRSLNFSFTTRYHLHLSSLLKGHTGAQRQVVQMRNSEDILGIPYFLIGQTTASAILVKTMLRYLAMPTKRPIAMMFAGPSGHGKTELAKRFGDLLNLPFHSVDCTSMKHTSDLFGARAPYHGHQEGSPLNNFLARNNGTRGIVFLDEFEKAGKDIRQALLIPLQDGTYQDRRDLSPVDCGKTVWIFATNAFDPTIHEFCRRNKDVIYDPRKMRESEKLMGDLSKDIRKESEGHFGAPITGRVTVWLPFLTFSPIEQAVVADKYISDFGREAVRPVQISNDETRDRLFGNVNLHIRQGWSLCSALATKGYVPELGARSLITEVDEQVRGPLVDAYLQNMDEIAEGGRTTQCLATVDADGAVKVLCAFPDKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWG4</accession>
    <name>A0ABR1VWG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_010200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3 6"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666477.1">
        <property type="nucleotide sequence ID" value="XM_066814515.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047575"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779:SF7">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045324991" description="peptidylprolyl isomerase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="9">
        <location>
            <begin position="40"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="20294" checksum="058DF1D1130D2E3B" modified="2025-10-08" version="1">MKNLIFPLSLVASAAVGAMAAELKIEVTQAVDCDRKTKKGDAVEMHYKGTLAANGNKFDASYDRNVPFKFNLGTGQVIAGWDEGLLDMCIGEKRQKGYGQRNMGPIPAGSTLVFETELLGIKGVPKPESIKYKSASSTASSAASDASSTASEAAETASEKATGGVKEAVASAASAAADAAGTMLVDTDDVQEHNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWP3</accession>
    <name>A0ABR1VWP3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666625.1">
        <property type="nucleotide sequence ID" value="XM_066814663.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047723"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="530" mass="58540" checksum="92B8366A9606EFD7" modified="2025-10-08" version="1">MRAIYSSCTRALLWMGELEEETQFADAGAGVAVLEYIAAFDPGTDSDSETGSDSDTDSHSDTASEAETSAGSETNNDSEPETSPKEAVAVPVPECAKSEEAFRAAMTALGLIGPRKGPWWHRVWMVQEAMLPPDAVFLWGPFSISWDTMDAATRAWVQTSDYEEHLTPSQCEMLHDPGHLGSLMATVIWMNCYNHETGEPPLPTAIKWRTRSATMPVDTVYALTGLNSGGVLPRSEKCDYSLDMRQVYINYTLDLIHRDGDGGDLQPLVIDPRREKPDDEADDEGLPRWAVDMRSFPKYDTVPWRQHHFYSRFEANKGLPRDHPPQYDGAALRLSGVAIDTVAEVGEGHYVKVDGTNEYPPIRPILRAWWTLYCKSLVANLDVPDDVLYCGLEPGNCDAYDRFCRLVSLLDRQDVARHLRTGEPIEHLRVSVGRAIKNRRFFVTVGGLLGLGHLETEPGDEVWVFSHGRVPFTLRPRRGGGGGSNTDGGGGGGGDDDYDFVGACHVQGIMFGDEGIREAAELGQRIARLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWU2</accession>
    <name>A0ABR1VWU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF1909-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009444</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665721.1">
        <property type="nucleotide sequence ID" value="XM_066813759.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046819"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039713">
        <property type="entry name" value="At2g23090-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039438">
        <property type="entry name" value="At2g23090-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788">
        <property type="entry name" value="OS07G0114300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788:SF1">
        <property type="entry name" value="ZINC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12907">
        <property type="entry name" value="zf-met2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="At2g23090-like zinc-binding" evidence="3">
        <location>
            <begin position="36"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="75" mass="8276" checksum="654A37B80BBE58F7" modified="2025-10-08" version="1">MGNGAKAQQKRERNAKDGKGVAKSQLKVNQQAMDIQCVICKSTFLKTTRAPQLTEHAANKHSKTLPDCFPSYEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX74</accession>
    <name>A0ABR1VX74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010529</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cell membrane</location>
            <topology evidence="1 5">Lipid-anchor</topology>
            <topology evidence="1 5">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666806.1">
        <property type="nucleotide sequence ID" value="XM_066814844.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047904"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF4">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044970492" description="1,3-beta-glucanosyltransferase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="425"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="456" mass="49890" checksum="C62CFEB36BA04600" modified="2025-10-08" version="1">MRLSTALVALGATAAAALPQIEIKGNQFYFTGNGSEFKIRGLAYQPGGQSAFKSDGADKFDPSRARTSSLGANVIRVYNLHADLNHDECVTVFNNAGIYLMLDVNSPVVNTHINKENAKSTYHHGYLENIFKVVEAFKGYSNVIAFFAGNEVIDDKKQARDNPPYIRAVTRDLKQYIKNHSDRFIAVGYAATDTRSASGAGKDSVVDLWNYLGCSIEGEEDDMSRADFFAVNIYSWCGDATFEESGYPELVKDFEKTSLPIFWSEHGCNEPVGSPRPFNEIAAMYGRDDMVKTFAGGIVFEYTQEANKFGLVKMADTKDTESSDVELMKDFDNLSKQYDDVDWNKIKNIKTDNMQVVAPPKCSSDLILGKSNGFASDFSAIPSLPSEAQGFMDDGLMDTVDYKFQQNIMDSNGKQVNAQFALVEMPDAKVNDAPSNKGPGGSSGNGDESAASSDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY18</accession>
    <name>A0ABR1VY18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009743</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666020.1">
        <property type="nucleotide sequence ID" value="XM_066814058.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047118"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF10">
        <property type="entry name" value="CHAIN DEHYDROGENASE_OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G15740)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="357" mass="38735" checksum="42E4C3D6DBCDF772" modified="2025-10-08" version="1">MYSCSRIARGVVSRHTPIAQCALKTTSTASTTRTAVIGASVPLWTQHRATIHTSHNRPANPVAPKPMNPDPRENPMVGIAPDKDVNVAQRRMADFNLSGRVFVVTGGGRGLGLSLAEGLAEAGGYVYCLDRDNKVDKRWEEAARRATEWGGQIRYRQQDVQDAAGMDRTIAAIADAHQRLDGLVAAAGVQQITPALEYRQEDAARMLDINYTGVLMAATAAARQMNKYKCRGSMCFIASMSGSVANKGLLSPVYNSSKAAVIQLARNLAMEWSPINKKDGTGGIRVNCISPGHIITPMVEKNFEEVPGLRDLWESENMMGRLAEPHEFKGACLYLLSNASSFMTGNNMVIDGGHTSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZJ7</accession>
    <name>A0ABR1VZJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010253</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666530.1">
        <property type="nucleotide sequence ID" value="XM_066814568.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047628"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF3">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="87"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="196"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="538" mass="58403" checksum="9B4BD08306842F0F" modified="2025-10-08" version="1" fragment="single">QNSEIFTTSSTMKDYKAIAAEKVAQRNSKIPKDWLISLETFKDATCLLDIPTTCGALSDAECEITSKYDATDLLAKLQVGDFSAALVTKAFCKRAAIAQQLLKQQVNCLTEIFFDEAIERARQLDSKRHENPSDPLPPLWGLPISLKDSFAYKDQDTSTGLACYVNDPAKEHSSLAALLLDLGARQQRLRAHAESRNTHLTAGGSTGGEGALIALRGSLLGVGTDIGGSNRVPSVCNGLYGLRPSVGVVPHGGVRDLTVPGTVGVMSSAGPLATSMRDIALFIRTVMQAGTWKYDSTVISLPWSNLNPAKEQRLRIGLVENDGLYTPTPPIRRGLKKAADLLGSRDDIELVPITLPGVGQIYQDLLSYYTLSGSDYYFEQFGRTGEPLVPSLQALESLLLQPGTTLKGFFDLNVRRGEAAKTYLSLFRDNGLDAILMAPAPHTAVPLDKWSTITYTGLWNYLDYPAIVIPVDHVRKEDAADAVSNAKFGTEDARVYSLYTGAKDYEHAPVCVQLVGYRHQDEALMSTAAVLDGTINKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7J6</accession>
    <name>A0ABR1W7J6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007272</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666929.1">
        <property type="nucleotide sequence ID" value="XM_066811587.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044647"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="881"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="969" mass="108981" checksum="23CE94EB12FB9101" modified="2025-10-08" version="1">MESEHGFPNDFTVSTYETTLRDHLGFRKNLKHSDWETIATHLEKPKGKESDVNFFGNRITHEKVVKETSRYRPRTRNAGIPTRVKPPPLPAGITISTPPSTPHGTIPDLLASHDISATTPKSGHTAASTNLVATALYGTPPGFSQVIPPPFGAADAERLLDGPFKKAWERLPFNQFATQLKTLREWTSYQYISALIDVFYPASLQNHRITEDMLRSLSYLHQMTGSPTVFGLNSSVGVLMHASYMLSNGHGRWKDSDSFFKWFGVVADMQLLRASFSQRTPTVTAAWFALPRAALSRYADKATQAWLEIGLTAIGGRMIAENLELFCDVLDYTGERCIWEMNVLVRQGSSVPSWMKRSYFDGISYEDPSDKLECVKIILEAAIAVDPRTDDQLHWIGPGEPDLITDWLWVRSQVSYRCDCISSHYGCISSNYGRFLKACSPYSEHMQTSVIVVGICGAASQGLKSLHDYVKEKPYPTYHTKQELLQVALSEASAHGLEGIVQVLLEYGVDVEVGLLTAWEWGLNGSGQEFGSFEWLPTFRSVMARDVGMITLLAQHGAILNRQEVMDATISDGWTLQGPHRASDKEIVVELLSSLGVDIQQYGPNTMLKAVGLLHIRDILWGPMGFRKPDTVLIETLQKYNVTWDHQYFNKEGQLLRWWERGFEKVGEMDLLQAAVRNGCKIPTIKYLLDEGMQVHSRPCEVDGKSMLHAALECGLYTEDEAFDVIHALLERLSSVEEDPVWPRVLGLSFSKIFPSMRLFHYLEGLGATLIPPTDHLQAKLRFNIIPRLLEAGADRVTINRVWDGGVGLDKLDQDDRLDIVQAFLRRRNINWAFTLIEGINLDKEGWQKILMEACNNGVCPLWFIRYLLQHGADGGRVGGNFWSPLHDAAEHGNLSVAHLLMEYDADINTIWNIENYQMPNDGNSVDYYYVHWYAGHQPQWTPLDAASRMGRLDMVKFLLHAGGRSGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W812</accession>
    <name>A0ABR1W812_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15">E3 ubiquitin-protein ligase listerin</fullName>
            <ecNumber evidence="5 15">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">RING-type E3 ubiquitin transferase listerin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_007440</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the ribosome quality control complex (RQC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the LTN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5 15"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667097.1">
        <property type="nucleotide sequence ID" value="XM_066811755.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044815"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16491">
        <property type="entry name" value="RING-CH-C4HC3_LTN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039795">
        <property type="entry name" value="LTN1/Rkr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054477">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054476">
        <property type="entry name" value="Ltn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054478">
        <property type="entry name" value="LTN1_UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039804">
        <property type="entry name" value="RING-CH-C4HC3_LTN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057030">
        <property type="entry name" value="TPR_Rkr-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE LISTERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389">
        <property type="entry name" value="ZINC FINGER PROTEIN 294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22958">
        <property type="entry name" value="Ltn1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22999">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23280">
        <property type="entry name" value="TPR_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23009">
        <property type="entry name" value="UBC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01197">
        <property type="entry name" value="FANCL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 14 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="16">
        <location>
            <begin position="1530"/>
            <end position="1576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8079622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1583" mass="173804" checksum="49E7E10CAE49660E" modified="2025-10-08" version="1">MSRRSGKAQAASGKAAFAAAGAGGFGAFSPPNFATISDANAAVSFKNLLKKDATTKTKALEELVSFVEAHPHERDGGAEEAILDAWVQLYPRISIDNSRRVRELSHTLQLELVRSARKRMERRIPKIVGSWLAGTFDRDRGVARVATDGLASFLTTPEKVTQFWRKCQTQILEYASDAILETVVSLSDERSTNADDAEAKYYRVLGGSLALVLNLLEKLDVADIEKSQESYDTFFQSEKVWTSAVVNENFVRRQSHQMVRTCLDKMPSMIEGRLPQLSKIYIAEGLKSDQTGSGADFVGTLLALTAKHPTIWTTDYKAKKSPLSRLQLFLEKGSQGGSALHWESVDKLLNTLPEGILPTDLEGATKCIESLRAGVVRREEPRSNAVAAWSCYLSLVRQFILKLDAEGSATKLVQDCLFPLTEQYLLPRPELSAWASGCQIPVVIKAYTSSAVSPKKEVVQATEQLWETLRDQFRERIKGSLPEASKDHEKSQKAIADEGSRWFALTGKILEGHTKTVATDRPIPDIPAKPSAELLVDALKLLETRQWKPFGAAATVQSSFKSSPLLFETSCADEILRQLEETVSTGGLALLRSASAPYLFSSIVDLGEVQGRQAEFIRVWKAIIASVLSAEDSKLAVQAVTMLISSNASASLAHQDEVLQEHLVRFCLDCAAGARDVDWKLYDGVLGYSALTDDSTKKLIKELVHRMANLNGQPSSGVCKGLLLIAQNDPQLLSADDEIHMSLMTSILSLSEQSNDPDLISLKALLDKPSTKPNKIEIIQHNLNDASVSSLTIETLVQQAMHLGDAAGDAQVLESIMPNVECWKKELATLCESTPNPALSLTSSLAGSYFLVAPDSPEPTGEMKRDRSGCSIAGRMAIYLSKMLSSDLVLSPLASDKQTDLLICLGVTAEVASDQLTVMGKKSVWTSLESETTQAYAEDIVSSSRKLLISMTDDASGWRDGSGSKNSELIHAIFNKLLETTKPPTTLGLYHARVLGELVQALTERHGFPSSAEDWLNQLQVLKSSPSSILPAAAILIGAGETLAASKAVSNFCNRLVSDVAGAKLDSDKTLGLLVVLNACMQVYEAGELPVANNRLVFAVRQITSWLETPEELDYRLATESCRALRYLLPCIKDVYGSYWERAIDFSLYLFTKTAGEPLDRRLPGINAALRLLTTIQALEEPNDDLVDVLQSTAETRSAALLELLNLSHEQGTQPLEIVETIVCRLVEKIPLDHVKDLSDLYGLVAADSRTIQTAAFSVLHKALPAAQEQLSLDVLLDKKTAKLPDELLSLLLEAPTLEAYSDEASYLLSWHLVFDAFQAASFKLRSDYADILKSENYIGPLMEFTFDVLGHSAASGLNLDKENLTVEHITSYDIKLAETEMEEKNMQWLLVHLFYLVLKYVPGLFKAWYIDCRSKQTKIAVESWVAKYFSPIIVSETLEDVTNRAAKEISVGYEVDEHEASIAIRVPPAFPLDGVSVVTVNRLAVSEKKWQAWILATQGVITFSGGSIVDGLLAFKRNVNGAMKGQTECAICYSIISSDKRIPDKACGTCKNLFHRSCLYKWFRSSNQNTCPLCRNPIDYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W976</accession>
    <name>A0ABR1W976_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667072.1">
        <property type="nucleotide sequence ID" value="XM_066811730.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044790"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="357" mass="39322" checksum="8DF41EB9B00CD660" modified="2025-10-08" version="1">MVNVTGQGQDEAARLARSRARMPRINLEYQLPVTKATLAPALKVGNHPSASSVTKKRRTRKAVKKPINPPKCWWYELPLESTKKPASKAPTSPSTATPRGTGKPPSPSHTRTAPAPSPACCGPARASTTTCGATRSSTSTSTSSSTSRSCCTASSRAPLPRWALEHVTHVDLEPRRVTVRCPGRAYSTTSAFQVLVGADDVPATAPDPDLVVAALPQVLPRLQQLRVIFSWHTDAELGVVPVAKHVIRELIAISDLRDRVPGKHHHHNDPSMVPKRDDFTFGFVVAVKFESWRGPSDPQNKGKEVYHKWCVHCFINEYRSKDGPIKKYGGKLRNMLKGVEWCVSTENHRAFRREKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9F4</accession>
    <name>A0ABR1W9F4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_007926</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667583.1">
        <property type="nucleotide sequence ID" value="XM_066812241.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045301"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04591">
        <property type="entry name" value="CBS_pair_voltage-gated_CLC_euk_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF9">
        <property type="entry name" value="ANION_PROTON EXCHANGE TRANSPORTER GEF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7 9" id="KW-0868">Chloride</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="505"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="589"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="698"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="805"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="815"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8080108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="831" mass="91148" checksum="D0D3A797B69079FB" modified="2025-10-08" version="1">MSSRTTSFSAAPLTRRPSSLTSRLSFAVSTAERGEGNDAPAAQQIDEEIAEIKRYEDAAREQLRRKAKRHRNAGLFDNGQVSWRHRVAESYDAAQGWIVVTLIGAAIGLNAAFLNIATEWLSDIKQGYCTTGFYLNENFCCWGEDNGCADWHTWTGFEPANYVIYILFATLFACLSATLVKSFAPYAAGSGISEIKCIIAGFVMKGFLGLWTLIIKSVALPLAIGSGLSVGKEGPSVHYAVCTGNVISRLFEKYARNASKTREILSACAAAGVAVAFGSPIGGVLFSLEEMSNYFPLKTLWRSYFCALVATAVLAAMNPFRTGQLVMFQIHYDRSWHFFEVFFYIILGVFGGLYGAFVMKWNLRVQAFRKKYLTKYAVLEATLLAAGTAIICYPNVFLRIDMTESMEILFLECEGAEDYQGLCETDKRWQNILSLLLATVIRIFLVIISYGCKVPAGIFVPSMAIGASFGRTIGIIVQALHDSYPQSVFFASCLPDLPCITPGTYAFLGAAAALSGIMHITVSVVVIMFELTGALDYILPTMIVVGVTKAVSELFGKGGIADRMIWFSGFPFLDNKEDHNFGVPVQAVMTNDIVTIPIQGMTLQSVEDLLAQPKYQGFPIVEDVNTRILVGYIGRTELRYAIDRLRRERQITISPQAKCSFSPSNVAGAIPVTPTVTVSNTDYNISSSASTIDFSRYVDPTPVMVHPRLPLETVMDMFRKIGPRVILIEYHGRLAGLVTVKDCLKYQFKVEAAENPQHSHDVQKGNELLWSWIQTAGLWVSGKLSSASGGRIRLGSTEIPRSVGRPLGGRGGIMDGDEDLGDEGGVELENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA69</accession>
    <name>A0ABR1WA69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667861.1">
        <property type="nucleotide sequence ID" value="XM_066812519.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045579"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="27010" checksum="138689D85E0CA980" modified="2025-10-08" version="1">MAPRILQLTSNGDFSNSETAGGSRFKHNRHVNRILAELRTIFPKNNELTISTVQYSPNKKDIGDTMFNSHRGKLLVQYQPAPKKCDDNANIDEAEQSKAMWRVWFEGHDIGDRHAEWVPADHQHLKRDERSCPIKAPTGTATPTTQGPAPTPTETQTDLPPPRRPRLLQRHATCIFTSTLRDPKLYLLRWTTTFTTGATSRNTQATLPEAGTKSTFADGRDGTRTPDFRDCDQPAAARCMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB51</accession>
    <name>A0ABR1WB51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008548</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668205.1">
        <property type="nucleotide sequence ID" value="XM_066812863.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045923"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF81">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="109"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="70"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="153"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="9"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="673" mass="74660" checksum="F6AD4D9B20D52803" modified="2025-10-08" version="1" fragment="single">RRMASPHFVQVLPPTSSSTSQLPQLPPQYGHYQQQQQQQQLPPPQHPASVTSPNGSVILTPTSANTIYSSPSSSFHVKNEVDDRDGSVGVADASEPSRKKQKRNKPTLSCHECVERKTKCDRGRPHCLACIKRQTECQYAHVANLLEETTRSATNGRRMTKPPKKKMSSVDLGDVRPPVPNIADRGLPTGRITAARGSVALSTGLLSNVPWSLPTASNVFGIGSEHPFANYWTCEGGLPEVIGVMPEKMQADMLLGQYFECVDPIYPMIHRQTFYADYEHFWSLPQAEKERSDAALVALIFVMLAMGTQFVTSTNPRDHKQTAEFYASASNQALRMSSYLSTASIRSVQAMVLICYFLINDNHASDGWAFAGILMRQAYAMGLHRDPKIVTPDATPFEKTQRRKLWQAVLLQDTFMTVLLSLPPSATHNDVNVEDLTDDSSSIASEDPTDTAYIRGSWTLANLVQETICSPRSLDLPICATQRQKSKLIGDFRAVYRSFPDVFRSWDTESLAHLAANNKRIVRQTLFLTSNYYHNLMLVHASESPDVPVNVRAALEAAHEAITAFFMLYTLFDHDARVWWVFNHRAFLEALCIGNLLRDYALKESNAAAAGVPMASYGVDGGGGGTDIERAERDPVFARARADITRMLNIMKVMGDEGSDVARTRVAVLSDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB72</accession>
    <name>A0ABR1WB72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">KRR1 small subunit processome component</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">KRR-R motif-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_008485</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the KRR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668142.1">
        <property type="nucleotide sequence ID" value="XM_066812800.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045860"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22393">
        <property type="entry name" value="KH-I_KRR1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22394">
        <property type="entry name" value="KH-I_KRR1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048550">
        <property type="entry name" value="KRR1-like_KH1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048548">
        <property type="entry name" value="KRR1-like_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048549">
        <property type="entry name" value="KRR1-like_KH2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024166">
        <property type="entry name" value="rRNA_assembly_KRR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581">
        <property type="entry name" value="HIV-1 REV BINDING PROTEIN 2, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581:SF0">
        <property type="entry name" value="KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21800">
        <property type="entry name" value="KH_KRR1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006515">
        <property type="entry name" value="KRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 11" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="6 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="K Homology" evidence="13">
        <location>
            <begin position="116"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="225"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="251"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8080667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="37376" checksum="EA33CFA573D7CEA2" modified="2025-10-08" version="1">MPSTYNVEKPWDTDDIDKWKIEEFKPEHNVAGHFVEESNFSVLFPKYREVYLRESWPMITRALEKRGIACELNLVDGSMKVATTRKTYDPAAILSARDLIRYGYICFWQDPFPLRKQSRIRNLVRSKEKFAKRRQRILGPNGQTLKALELLTQTYILCQGSTVSVMGPYKGLKEIRRIVEDTMNNVHPIYAIKTLMVKQELMKDPELAKESWDRFLPNYKARSLSSRRTPYKVTDKTKKNYTPFPPAQEQSKVDKQLEAGEYHIGREAQKRIAQEGRMEKQKAKQEEKKRERERDFVPPEEGGEKKKKKRKVRAEDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCZ1</accession>
    <name>A0ABR1WCZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667805.1">
        <property type="nucleotide sequence ID" value="XM_066812463.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045523"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="166" mass="18569" checksum="A830562F13C2CBA0" modified="2025-10-08" version="1">MLVALVLYTAEAILIQLFVENAYDLEKAENGDLSVIGPDFLSNSGKAFVALGTSINITMVGVLVIKLSFLLFFRRLGTNIRFFNPVWWGIMLFTVAASAAQIGMQDFQCFFANVNDILSDRCTSEPVLHRIFINAVFSAIVDALSDFLSEFAFLHHIWYEVERGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDI0</accession>
    <name>A0ABR1WDI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the secreted LysM effector family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668542.1">
        <property type="nucleotide sequence ID" value="XM_066813200.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046260"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045047643" description="LysM domain-containing protein" evidence="5">
        <location>
            <begin position="20"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="23"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="87"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="236"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="348"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="140"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="524"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="140"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8081067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="621" mass="64407" checksum="5C50F4ACA507F839" modified="2025-10-08" version="1">MKIMELLLLLACSLSLAAASCSQPYTVVSGDSCWSIYTSHGLSSDQFYAMNPPLSASNCPLSIGQVVCVGNSQGQSQSQGQGTACSQYGAVKSGDNCNSFIARYNPSMTLQQLYVLNPQINSGCSNLAVGQQLCYQGAPPTTSSFSSTSRPTTSSQTSRTSKPTPSTSVPPTVASSKSSASSSSASIPSSSSSSKIGGPMSSSTSGGIPTSSSAGPMPTAIQGMNLTNSLPFSCNTTYISTVNDTCGSIAANFSLSLNQLQVMNPNLACNNLQNATALCTRDGRAGCLAFTEIANGDTCASIAARAQIGLQALTAYNPDLDCTHLPSSIGVPLCTSLMVPPCASLSSSTYYVQPNDTCASIALSQNTTLDNIITLNPVADCSAVGVGAQKLCLQRDISVKLPDQVNYQLLGLLVNAFHSNDSTLVPKYETYLSAPSNVSAAAVMNELYPMFLTSGGQQTLSGLEATNHFIAGLETAYTGKTRADYCNITSAGAPTDVSRCFCGTSYPFLTCVAKMYQILNSKNATTSQPMHKRSPAGASLLSSRPKRSKRAKAAKREEPDCSLDQAFSFETAISANGASTSANTEKCFGCEVCAPIPGTILCFKVGAHCVPTSVPVSTTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDI2</accession>
    <name>A0ABR1WDI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667653.1">
        <property type="nucleotide sequence ID" value="XM_066812311.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045371"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="21783" checksum="776CEF778EF7B85D" modified="2025-10-08" version="1">MHYQLSFQHMCIQSPVSYKIHFTYLKRARHFSRFLASSSSETKWTGGVKNATEVASIACLWSFSALSCLTIYFHQTLQRPSQALVPSGLYRVAGRVITPLAYLMATEPHLCLLRFCRDEDMGLEPEQRVGGGRDLHADSTSTSQDHGGAGLHIADGFDNLLGIDGDGPKTFFLFVLIGSVVVANGDFALQPQTSLDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDL2</accession>
    <name>A0ABR1WDL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008373</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668030.1">
        <property type="nucleotide sequence ID" value="XM_066812688.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045748"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="163"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="421" mass="47212" checksum="56374400F73A6FE8" modified="2025-10-08" version="1">MAEVDSAPQSAPQPRRKFAVPPVKVACLAWCNGERPSCASVSHKRVPRKPAGRKYQRQCIYKPSRRGGPRFRKKTQPPENSQEPDTLNPRDLKRDGISLSIENYIDPGAGLKNLGDALNDSDALFDSLFMNSHSDGSHANASPNERETNDPMVRVYDSDAEVLNAYYIWIHPFFPILPAPHGSPRPDEPTPFFQNRPNDIDESSSPLGLAISALLALIPCPQDRNSLAEDSVVFRRKYAQFVAQAAIESIELDSERPESSVEPRKALEDPDDVPRRPAFCPDVPIDLESIIALDILSVYEYAQRGNLKKTKNRASTAMMFAMDLSLHLKGDVEDAYAECRRRVWWMTYICYCQSCIVSNTHPSFAIFTPSFTAHPPTIKSDPQAWYWFMKSQQAILAATEFVIDLNKAMATEADMTLHINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEI7</accession>
    <name>A0ABR1WEI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo-keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_008734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668391.1">
        <property type="nucleotide sequence ID" value="XM_066813049.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046109"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8080916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="356" mass="39585" checksum="8469AB93D078C67C" modified="2025-10-08" version="1">MVPAPIIRTLGKNGPKIPALGYGLMLIGAPAYGAVPQDKDRFAILDKALELGATFWDTSDLYGDNEHLLKQWFQQTGKRDQIFLATKFGYVNGKEGKSMQFQYDTSYKYTKKACQASLDAMGTDYIDLYYVHQVDNVTPIEETMRALAELQAFRNYSEGKIKHIGLSMISSATLRRAVTIAPVAAVQPEYSLFGREIEGPEGTDLLATCRELGVAVVCATPLGRGLLASDFGSKVEDATDPSDLRAKVMPRFLAEKRAHNASVVAKIREFAAEREGCSVLQLALAWLLKQGDDIFVIPGTRRVKYLEENWAANWIELSDEEEKELRQLAETSELAGEALPEQFMDHKFKDTKELSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLJ2</accession>
    <name>A0ABR1WLJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinetochore sim4 complex subunit FTA2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668866.1">
        <property type="nucleotide sequence ID" value="XM_066809943.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043003"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025213">
        <property type="entry name" value="Sim4_Fta2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13095">
        <property type="entry name" value="FTA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="301"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="344" mass="40211" checksum="B8B81D45D8FCE82C" modified="2025-10-08" version="1">MGSLPPAPGPKLAEFKGKRTGETLHIDFIQYLGSGVHAHVWKVRIDGEIYALKMFRFVNNFTPASFFHVKLNQEEEVLHMHPFNCEARAYARLKEVNQEHVAVPCHGYILLDQEQQRILREKDTTCDWVKDWYYCGSYAGQPIQALVKDFIEFDNVGYYENGPGDNLRRITRAIDSSRTARTLLDNMAILHRVGILHKDINNSNVAQGRFLDFSTSWIKPHPCLDTRQIESARDPYNQLGITDAYAVDQIIKHWNMLQPPKLRLWFRAAQDRDYIKRLRSYGKRDKGQKDVMSEYIRKYPGRPDLYKWDPENPNAGQRNAPSRRHDRSRNKQARKIKRQDRSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM36</accession>
    <name>A0ABR1WM36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AAA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005854</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669092.1">
        <property type="nucleotide sequence ID" value="XM_066810169.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043229"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19509">
        <property type="entry name" value="RecA-like_VPS4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF17">
        <property type="entry name" value="FIDGETIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="514"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="95"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="317"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="772" mass="83698" checksum="B710C0B14C9788A7" modified="2025-10-08" version="1">MWPNKAASNLQKTYDESYLTCSTAVYYESQGNEKEAMRYWKTALDQINHNSPSKPSYTPKSETERALLESLKTLETQCKERVDLLEALRISREEDVATKRNSSSSGTNGAFQTVAPPRPSMAVRNSSERAVVGRKDGTGVEQSSPQSSAKQRPPLPPYASSTTPMKKSSRSPSPDKRTMRTTLRSGRSSEKAAKASPRMTPKSAERPGASKAATLAWSNISSRENLGKVSSSDLHSPAAALGEPRRSVEQTRKASASAYSQWDSHTRRLVTPDDGALDPMSPGSPSTRHTEDYTFPGPSSLALGAASSALSSLAIGERTESAFSRSSRGPKPHNGSMAAQDAARASANAGADAALASGRSSAEPPFRRKPVAHRHSPSQPNSAKKRTPRPRRDKKLGHASTSEDDEEYVGDARLKEPESPVPADLTVDSPDGSGEEREDKAKLEWEKKKKATLKRLPPGVDSAAAKAIFNEIVVEGDEVHWSDVAGLEIAKSALREAVVYPFLRPDLFMGLREPARGMLLFGPPGTGKTMLARAVATESKSTFFSISASSLTSKYLGESEKLVRALFALAKAMSPSIIFVDEIDSLLSQRSGSGEHEATQRIKTEFLIQWSDLQRAAAGRESSPGGKGESRGDANRVLVLAATNLPWAIDDAARRRFVRRQYIPLPEPETRATQLRTLLGQQKHSLTEADILELVELTGGFSGSDITALAKDAAMGPLRSLGEALLHMTMDEIRPIELADFKASLRMIRPSVSLEGLKEYEDWAKQFGERGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WND6</accession>
    <name>A0ABR1WND6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_006293</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669531.1">
        <property type="nucleotide sequence ID" value="XM_066810608.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043668"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013910">
        <property type="entry name" value="TF_PAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023167">
        <property type="entry name" value="Yap1_redox_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08601">
        <property type="entry name" value="PAP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111430">
        <property type="entry name" value="YAP1 redox domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="157"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="272"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8085022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="581" mass="62446" checksum="7C7183C64E0D0BDA" modified="2025-10-08" version="1">MASTTSTQGLPHNFILTPQQQSLLYRALTSNQPANGSPPTDALSVSPSALKQNGPSKVDSVQESPYQDYDYDFGSGPDSGFDFDFANGAAGQMIGDLPNMSPGDSNDSSKATSPENDNAEKRSYPDEDEGDREENGNKRRESEGKVPKKPGRKPLTNEPSSKRKAQNRAAQRAFRERKEQHLKDLETKVKELEEASATTNNENSQLRAQVEKMTMELNEYKKRLAAAPTPRLSSGPSPKSYQQGVFGAGLVNTMNDVNFQFEFPKFGLLPGPSEVTSPTTGSKAPKRTTSASSPTTANGYAGQSSPSRQDQATPSSTKSRENSTSQPKDATSKYTGMPNQSPYEVGGNASRSSLDSGNFSIGGTTSTSPSSSHSNGGPSSSCGTSPEPFTQSPLGFKPVDTLTTIGEEQSGLTVDNGNHMGGFGSFDFSNFDWLANQNGGQFDPQLFGDYREPQDNILANTTFDDSFFNDAFDADFITPYNMAPSPNVPKKNICAEIDARKEEEDTIVTTENGKLLTCTNIWEQLQNCPKVQSGDIDLDGLCSDLQKKAKCGGTGAVVDETDFKAVMKKHLGGDESQCPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP22</accession>
    <name>A0ABR1WP22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006449</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669687.1">
        <property type="nucleotide sequence ID" value="XM_066810764.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043824"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051913">
        <property type="entry name" value="GH2_Domain-Containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42732">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42732:SF2">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046892450" evidence="4">
        <location>
            <begin position="21"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolases family 2 sugar binding" evidence="7">
        <location>
            <begin position="56"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="5">
        <location>
            <begin position="254"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 catalytic" evidence="6">
        <location>
            <begin position="391"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8085178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="639" mass="72436" checksum="8989B4071B53E8C4" modified="2025-10-08" version="1">MHVRGQVLFGVLAVVSQVLGYQVQTPPLDTEWTYKVGTNPWPEYPRPLLQRPQWQNLNGIWKYRRANAFEARMAPINEVSTRHFELYQLEEKDPLKVPPADQISYKSFANAADVLVPSCLESGLSGVQDINVTYAWLTREFTVPRDWAQKGRRIMLNFEAVDYEATVFVNGRRAGFHRGGYWHFNFDVTDFVRPNGTNTLHVHIFDPTDGMGYNIPMGKQRVDPSHIFYRACSGIWQTVWMESVPQNYIQKLDISADADGKVKMQVATSGGNDKLSISVVGNEGVSIMSHEASSNTPIEFVVDSPKLWSPDSPNLYNLSIKLGDDEVTSYTGFRTVSVGEVNGILRPLINGKFFFHFGTLDQGYWPDGLHTPPSREAMVYDLEIKVEPALFYQACDQMGLLVIQDMPALTDDGNRKPNAAQQAEFERQFEIMIDQHKSYPSIYTWVIYNEGWGQITQGYYPEFDLAARTKELDPTRLVDATSGWYDHGAGDFHDNHHYANPQCGTPFYSLNSSPHDPKRIAIQGEFGGIGHNVSAENLWKVTDAVNSINQTYELDADLEAYNYRGHILMSELREQIERYACSGAVWTQTTDVEGEVNGFLTYDRRILRLKVDQWKADIQALYDAAQGRTGESKAQKTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQD9</accession>
    <name>A0ABR1WQD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670201.1">
        <property type="nucleotide sequence ID" value="XM_066811278.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044338"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="249" mass="27550" checksum="66175249954FAE4E" modified="2025-10-08" version="1">MDLMIAETLSPVNGFRYCIGAKQPGSLDLCQKLLEYDTTESPEAYMASYGERIVEGEWDPDVFFRVKTQYKDLFDMENELAEKIHQLGAIDLRQIMLRLCLDPKHREAVVEAIGLLPKDGAKELAEPQPSEPSSSWTPPTPDAQSEGLEPPKEPASRASSVNTTSNTRQKWTVVLNPKSLIWTTLEASSVPSDYDSENGRKLIPHGFNWSCCNGLGPDCPPCVGLYHEPRPKDTHATGLSDIESGDGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRS1</accession>
    <name>A0ABR1WRS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycoside hydrolase 131 catalytic N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006279</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669517.1">
        <property type="nucleotide sequence ID" value="XM_066810594.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043654"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041524">
        <property type="entry name" value="GH131_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612">
        <property type="entry name" value="GH131_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612:SF6">
        <property type="entry name" value="GLYCOSIDE HYDROLASE 131 CATALYTIC N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18271">
        <property type="entry name" value="GH131_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045044036" description="Glycoside hydrolase 131 catalytic N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase 131 catalytic N-terminal" evidence="3">
        <location>
            <begin position="23"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="348" mass="36473" checksum="ABDBEBF8E7734A63" modified="2025-10-08" version="1">MMFASQISSTVLLAASAVSAGNVLWDGRFNDYASAADLDKWSFSNPVGEYQYYIHGKGETAEYVGLSADFKNPADGASKQGVKISLTDSAFWNGQNMRRTELIPQTKAAINKGKVYYHFSMKRSETNAPVANREHQIAFFESHFTEMKAGSNGDADPALRWFADSKSQWDTAWDADVWHNVAYEIDFDASTVGLWHSTGADALKQVVKPVKASTSSNGADWHLGMLELPGSGSTDENEDIFFSGVYIESGDLTTAIGSGSAAGSADAPAAAKPVASSTATAKPVASSTAIVKPVASSTAVVSSAAPTTLATSTKAPATSVAAQPTQSATSTAAQATATATTQPKPKCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRT1</accession>
    <name>A0ABR1WRT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669970.1">
        <property type="nucleotide sequence ID" value="XM_066811047.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044107"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="299" mass="33563" checksum="04497DD5F8F04FDE" modified="2025-10-08" version="1">MPPAAAARGRKRRRAEQDDGEDSSGDLTLEGVHGGLPTPPRTRGRPRKQSQVTGDDDDDTPGVIAFQVTREALDMLRETLAKLESMIKDTCQGCSDGNLRTLQLDAMSIHNDIMGLHLDMISAQASDANIEREAHSFQRRSFKLHQAVNKMPPQKTKPKAAPTKIKLKQTTRRQTRDSSAATEAIEKAEMATQTEQEKKKLVETAELAVQTKDLEPSFPAVPASLRAEHKISKIPRFFLETLSHHRYEEFSAEEVAKAFKLGSRLGEFMQTDVFFNKDYSNIHGDLVGDLYNRYTQRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRY1</accession>
    <name>A0ABR1WRY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669727.1">
        <property type="nucleotide sequence ID" value="XM_066810804.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043864"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="160" mass="17742" checksum="46F8B2323559E2CA" modified="2025-10-08" version="1">MSYLNIAFRDWVTNWELDTIHKISCYDGLGNYSLELDNAGRRTVGVIGNLLLDRYTSRETAIHLVDIRWTGLGGQGIAMRGIWKVLCLAIEIFCCHRSSRVKLAATVAQMAPFDLVRSAKAGLEGPLAGWSSAFIAHFASRSKTLPPPPCFRHCITHSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY54</accession>
    <name>A0ABR1WY54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PHD finger protein ING2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_066807298.1"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
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    </dbReference>
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        <property type="entry name" value="ING_fam"/>
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        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
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        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
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        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF94">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inhibitor of growth protein N-terminal histone-binding" evidence="2">
        <location>
            <begin position="74"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="826"/>
            <end position="869"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="204"/>
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    </feature>
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        <location>
            <begin position="286"/>
            <end position="295"/>
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    </feature>
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        <location>
            <begin position="422"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="558"/>
        </location>
    </feature>
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        <location>
            <begin position="559"/>
            <end position="583"/>
        </location>
    </feature>
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        <location>
            <begin position="612"/>
            <end position="634"/>
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        <location>
            <begin position="635"/>
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        <location>
            <begin position="660"/>
            <end position="672"/>
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        <location>
            <begin position="677"/>
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        <location>
            <begin position="694"/>
            <end position="706"/>
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        <location>
            <begin position="786"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="828"/>
            <end position="849"/>
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    </feature>
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        <location>
            <begin position="850"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="919" mass="99018" checksum="82575B655907E884" modified="2025-10-08" version="1">MASAVEANSPSMADPAPATVAERNSDDMDIVDEGPMSPTSKQEPAIPAQPIEAPTVNNTLDSFNMRADPDAQATVSDYIDFVDHLPSDIRRSLTLIGKLDQTYADSSIKVNKLTSTWSKLPTLPADQRPLPAQLRAEISENLNRAVSSRTSSYAEACRMSDYVNRHVNRAKTILAKLQTMRENYPTEEQRSPVQTRSPQMSRTPKVTLRVDKDGQKVRGPPRITVPGEVLAPYDIDFNAYSSFSEESSDEDEISVSPARMSPAPRIKLVKTPKVPKDKVPKAPRQPRQQAASGMPMLSTSTALAKLQPPPENAVPGSHDAPWLQLTAYELARLRKRMKKNAVWSPSDTMIARELKNLGRGIEAYRAAERKAKDEGRPFEPSLPAPVVDADSGVQHPPEGAISAEALGAEEVQLSNRGMKLNEAKKLKREAMSKLAGDDAEESTRKMMETARQLLNHEASPSVAGSVQGKGSEAGPSQSSSQSQSKAPKKPREKKRKRDSESEVPATVKAETIETGNGVQQSIKPQVKRTKTETPVPPPQIPRPTSLPPPVETPVPPPQVVQSTPVVSTTPVPLPVQPSVQPSPNSTASAVKPAISPTTGTSPAPVAMPMRSATPVPAPANNNNNNAANTTTTVPTKPPAETPIPPPAKTSTTPILPPTRDLGKRETRKDHKSLQPIATNATSATNATNTTNATPKQPSSRGNTPVTTPVPEPQSATSRRPVSRGKAGSQEPPTTLAVERPRRASTARNTPVPPGTSPADAVGSRKVPPKKRPRGPNKSTSSKQVEPEAEVELDEDGNVIDPDEPRYCMCNRVSFGTMIQCDNVDVSRTDSTSIEPSTPSPTATPASHSTRSNERRKVIPDDSHKLTGPRTQNCKQEWFHLECVGLNAIPARTTKWYCPDCRVALNIGGRGEVTSRGVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYY8</accession>
    <name>A0ABR1WYY8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxysterol-binding protein-like protein OBPalpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003347</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671280.1">
        <property type="nucleotide sequence ID" value="XM_066807662.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040722"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="417"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="431"/>
            <end position="456"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="500"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="510" mass="57023" checksum="A600D2AF4F9DEF90" modified="2025-10-08" version="1">MHAKTLSFSGRHRTASNASSRSSLDGDADDDTLVVEPDQGNVLMHIISQLRPGADLSRVVLPTFILEPRSMLERITNFMCHPEMLLGIPDLENPVDRFVGVVKFYLSGWHIRPPGVKKPLNPILGEIFTCYWDLPDDTRAYYISEQTSHHPPKSSYFYLVPDHHIRVDGTLKPRSKFLGNSAASMMEGTAILSLLNRGKDPKKGERYILTQPNMYARGILFGKMKYELGDHSFVRCPELGLVADIDFKTKGWVGGTYNAIGGTIKNEQTGEILYELSGLWSDEMFIRDVRTGLKEMFFNGAKARPAKYQVRPLEEQDERESQKLWYNTAQAVLDKNHELATDEKTRVEDMQREEAAKRAAENVEWHPRLFRRVKGGPGGEEEGEEELEWIINAKIDGSTPAKQAEQAMAIYPVVAGQKPSQRNVIPPRASSDLSRTVSTQNKDLIDVSQSHESPASPTALKDPVSETIAEKRGSKQSADIRGMLEGTGRKSDGPLIDFAGDMKKDLPKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZC4</accession>
    <name>A0ABR1WZC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003481</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671414.1">
        <property type="nucleotide sequence ID" value="XM_066807796.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040856"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DUF7708" evidence="4">
        <location>
            <begin position="139"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="5">
        <location>
            <begin position="357"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="1044"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="1077"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="756"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1145"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1150"/>
            <end position="1166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1172" mass="131766" checksum="C2771B8785BA737E" modified="2025-10-08" version="1">MLEIFGGLHACDGNSGWVNKVISNSLPFLPMRIEKSEDPLVLTWIRDAISDSKWAQAVQSLSDDDREQFGIAQPSSGQDPLGILEDILAATEAKKEESLNKRWKVTVKGRTIIIRDVLEKMTLWVNNRNLKAIGSLALQYDPTGAALPWAAIKLFMQAAVNDVEIFAYTLTALEKITNIIGRSQIFEQLYLNQQNATNSESVFHQLSASVIRLYATVLQYLAGVLRYYRTGTAIRFLKSTAKTKADLEGEFRRLEEAQVETLRLAQLAEAQRSEDVALAITNIKEQQSKLDEKNASRFDELRETLQDFERPISRINAQLAQVQDKLDHESRVKILRAISTIPYTTHHKVASQGRLPGSGQWLLNKEVYTSWRASSSSSVLWLHGIPGSGKTKLATLVVDDLKASEHIAFFYCMRNPSEPFRALCQPILASLVRQLASVDPSKPLLPPVVSQYQDALDDYIGFEDQSWAIDDCRRVLTELSNEYPAVTIVIDALDEVDGEDRQELMDALGELLQESTSLVKIFISSRDNTDIALSLEGSANVYIEADDNAIDIEAFMFRWVELQIQSLRKLKVAADIKARLGHLPETLEGAYWEVYQQILASGENAAKLAIFTFQWLLYAQQTIPLESFSRFASIALSDDPGIVYNSHEIVDVCSNLIVSRSDSFQFAHLSVREFLEHLQKRQVTTMMAEDGHAALARACLLQLQAIASVTTRLDLDRTQRYRDLVNPKKPIDRAPLTSEEVAKDDAERWFLNHLFAGDNSDEEPSSDEDPRDKDTSDEVLITTSAEDQAMVKRDEAIDDDVFESPMVLATRYAVTFWPHHMTASNKLRSEPHLRQLSNLFLVDSAERTVAPGFTIWCRLWREMENNPDDPDAWDSTEDPQTHCGRSAFTIGQSSSTIFTKRIIQTWKVTGSYGMRREKGTDIQAVGYEGLYSACHCGSSSCVVFILDHGGPIEPGWKLLSCAVSNCHVEVSRILMERGIGMERLTDLFHLVVASGYEEMPPIFYKYNPRKEPVAVVKQIVHDAENSALNLVKAGWEIHGRYLERRRTALHYAAEKGQAKLMAALLERGVVVDLFDRSRNTPLHLAALRGRDKCVELLLYHGADVLAEDRDGNIALDLAERYHHPSAARIIRGHMERLLEELRSKMDERTGQSQRVPGSAEGETSVQGEIIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZL0</accession>
    <name>A0ABR1WZL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003571</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the flavoredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671504.1">
        <property type="nucleotide sequence ID" value="XM_066807886.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040946"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33798:SF5">
        <property type="entry name" value="FLAVIN REDUCTASE LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33798">
        <property type="entry name" value="FLAVOPROTEIN OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="6">
        <location>
            <begin position="71"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="281" mass="30758" checksum="7C72EDCA4A00A68E" modified="2025-10-08" version="1">MSSSISTESEKLIQRNPHPDFKKVEESRPDWDTSAAFRYTKTADPSWQLGGGANKLHAAEDAAKKHVTIDPSIVPRPIGFVSTRSPDGSATNLAPFSYFNMVNHDPPLFVLGFAGNLERPKDTLKNLVESKECVVNIISEQFVEAANATSVDAPYGASEWDVSGLTPVSDCREVKAARVGEAVFSVECKLESAREFESRATPGKKTGVLVVLEGVRFWVREDAINEERNLVAPEVLRPMSRLGGITYGRLTEGLEIPRPVFEKDVGGMEGYEKLKSNNSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0M3</accession>
    <name>A0ABR1X0M3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671864.1">
        <property type="nucleotide sequence ID" value="XM_066808246.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041306"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="225" mass="23804" checksum="FED56962454DBB5D" modified="2025-10-08" version="1">MGLRTALKKKLAHSSERRDSDTAVDEDTISKESNGTPERSPERLSAASSSGSLSPPAEVPAISLSDESLAEPVITGKRKPSGTPRSSNETTKRPRQNSDVTGKRKPQDTAALVDSRPRANSYQPPTGKGEVEPSPADYLYFGPKEEGASLPNRYGSVAAGDATNRNRARHTSSSSGGGHAAQPSRTDDSGFLNTGVAGARQQMGYQNLTYGGSLQYDYSGTQAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0M9</accession>
    <name>A0ABR1X0M9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003950</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671883.1">
        <property type="nucleotide sequence ID" value="XM_066808265.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041325"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF74">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="256"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="634" mass="71411" checksum="F485D56FBDD03C1F" modified="2025-10-08" version="1">MSDESPQNGIGDNASRSSTPQSRPRPPLNRRRDKPQLSCNLCRRRKRYSCLTPRDTLAALVSADHIPGTATDWSVLLDGISEGREQRSDSSRSPAESDHSSHPSSPGPKLFYSCPPATRADILASLPPRRTSDRLISAFFNFLDSAAAAIVHSGEFLNAYKRFWDDPSSVSIIWISMLYSVLCIASRVQHTVGFQRDRSTQEQAKPTSETTSGYQEKAVQALMLGQYTKGGPYVVEALLAYFTAEHFTSMDAQIESWLILSVTVNIAMRQGYHRDPRHFPQLSPYEGEMRRRVWATLYQVDLSISVQMGMPKLIRDSVSDTRLPGNYSDTDFDSSTAQLPAPRAETDVTPLLYTITKTRLVRVIGMVMEHVTEVQIPSYEEVLRIDAILDDVYANVPDVFRWEGMSESILSSTAVVSQKFFLHTIYQKSKLLLHRQYIPSQGQQQGLEKYEYSRKRALEAGLAILRLHHIIVEESKPHGQLYSSQFMFNSLVSYDLFAGALAVCFYLQHHRANLEFEKLQETKRLLRKSQGLWIEASSTSVEAAKAAEALRIFLNRLDEETLAQQEPGDASSSPAFFTTDLMPSEVFQDSFWDIRLPFTYFPVDMPGPRTEEPVMLMIDGGQEVGTSESWVATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X135</accession>
    <name>A0ABR1X135_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell cycle inhibitor Nif1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671979.1">
        <property type="nucleotide sequence ID" value="XM_066808361.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041421"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF11">
        <property type="entry name" value="PROTEIN DSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="705" mass="76563" checksum="5B0B30C0596FA238" modified="2025-10-08" version="1">MANRPDFIDLRSTSSASGASAASVASSQRPLRSPRLHVAGEVPPALSPLDAFAAQSRLLAKQLEESNKQGRRMSRLPPLTVESPLVVQGRSEYFRSLSYDSSEDHDETPMQKTGLGLLSENEPHTANPGRNDTGAPNPYVERGFLERGRQLDRLDEADDGMFGARREQSPGDLDSLPERMDETGPTEPDPSSRDAGQVVLNDDTPISVPPSPEKLTRQISHESGLAPPRSMFPKRSSSIMSAPLESHNDDTLSASFHSQPPRKLSADQEPPASTHRLGSRHHPRQASQDSQPSFVLGDDAAQTPISMHSEAFGDNVGEDGRGAPSYIYTKYSLPRGKALQRNSGMFNPDEVSQFKWEEPMVHPSNVQPFNKGHAPPSPPSRPSSSSSRYLDTAPAADSYLARPSLERSKLSNEVSLNGEPSPAPSRTSTSDAGRPSEDAPRGRPLTSPLHEQTRGRTPMSTTTSDSASTVKPARSIAPTAAEMSAEEHLEKGIKCHEEGSVKESTYHLRLAARGGSPTGMLLYALACRHGWGMRPNQREGVEWLRKAAEGASVEIAEDEGNVKDGKTVDFTERKTRKAQFALSIYELGVSHMNGWGIEQDKALALRCFEIAGSWGDVDALTEAGFCYAQGVGCKKDLKKSAKFYRMAEAKGMSMPGNSWIHKSKYADDDDAVSVKSKKAVRSKSRGRHIFGGKKPKEAEAGKGKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1C0</accession>
    <name>A0ABR1X1C0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF952 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672120.1">
        <property type="nucleotide sequence ID" value="XM_066808502.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041562"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.20">
        <property type="entry name" value="Protein of unknown function DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009297">
        <property type="entry name" value="DUF952"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129">
        <property type="entry name" value="BLR1139 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129:SF1">
        <property type="entry name" value="DUF952 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06108">
        <property type="entry name" value="DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="14885" checksum="9F0940FF643F3469" modified="2025-10-08" version="1">MAWTPPSPLPKYVYKIIPAAPPSPIPETYPPSDLDKQDGFIHLSNAEQVPKIADMFFAQASSLWVLKLRFSPPFAEKTRWEGPMDGCAHLYGEFGAADVEDARQFTRSDDGGGGGGGGDESWAATMTQGDGEHAWLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1I0</accession>
    <name>A0ABR1X1I0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672167.1">
        <property type="nucleotide sequence ID" value="XM_066808549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041609"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="557" mass="61870" checksum="8F7DBC727C20D3FB" modified="2025-10-08" version="1">MNNLTQDSTNVLAEKLALTRELAVLKPELDHLRSQLAHQQETLAEKLALERQVNTLEVELANEKKATKRAMQKRESNDRVEDDLRKKLREAEKSLATEKAQRERLEDQLAQEKHTHNLAIQDQDSTREVESDLRKKLQDAQREAREAKEDKERLEEELEAEKRRSKKAHSKASDNTVEADLRAQLEDFEKKLAVEQKQKEKLRHQSQESLTEAEARNDALEKKLEKMRTKTRDIQEQLKQCQSDLRKAQKAKPTLSEEIAAKTTGRHAFKKRKGHDIGSDEISQISIATPNADEKPRKGPKKRFVPEPSLVGEKSTFSITPFLNRGKTGMDSTGGLDDDDELGDTSIIPQQFANNPGARTASVLVPDEDEDAHSLPEPAEAAPAEAEEPQPAVKSRGRPKKALADAPSARKNSQPRAKTALKKGSKVAKLAQVAEESEAPGGQEDVVDTAAEQTQPGKVNFTMPEDAGASSTKVSKGEEPKEEPKKKKRKVLGSTKTLFDEEEGEEGEEVPAKAPKAQLKGVLKGKRQPPGVRNAFAGKSFSPLKRERRGVGASFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1Y8</accession>
    <name>A0ABR1X1Y8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_004404</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 21">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 21">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. BUD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672337.1">
        <property type="nucleotide sequence ID" value="XM_066808719.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041779"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022495">
        <property type="entry name" value="Bud32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03724">
        <property type="entry name" value="arch_bud32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209:SF0">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TP53RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209">
        <property type="entry name" value="NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="37"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8089443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="32061" checksum="B7DF6CC62B7F8C84" modified="2025-10-08" version="1">MATPEPAAAIQPPPPPADSTSTHEFPLPPILQHPSAAGPAKLITQGAEGRLYRTSWLTPTRLCALKHRPSKPYRHPTLDARLTRHRILSEARILQKCRREGVAVPALYGIDESQGVLSMEWVPGRPVRVEINEFLRRRAENYPHGEGGRGREEVTRDEEGAAPLVGLMRRIGEAVGKLHKAGIVHGDLTTSNMMVRPWEKDKGLTKGHHGNGQEYEVERSLEGEIVVIDFGLASQGSADEDRAVDLYVLEQALFTVVLEAYKETFKAAPVVLKKLEDVRMRGRKRSMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X216</accession>
    <name>A0ABR1X216_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Autophagy-related protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_004421</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 19">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672354.1">
        <property type="nucleotide sequence ID" value="XM_066808736.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041796"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14009">
        <property type="entry name" value="STKc_ATG1_ULK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048941">
        <property type="entry name" value="ATG1-like_MIT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022708">
        <property type="entry name" value="Atg1-like_tMIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF22">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12063">
        <property type="entry name" value="ATG1-like_MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21127">
        <property type="entry name" value="ATG1-like_MIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="25"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="335"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="535"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="809"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="349"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="549"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="578"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8089460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="973" mass="106463" checksum="6A281E0FE6658A9D" modified="2025-10-08" version="1">MADRNSAGSSASRRSRASDHSIGQFLIGAEIGKGSFAQVYSGKHQTSGALVAIKSVELGRLNKKLKDNLYSEIQILKKLRHPHIVALHDCIESSTHINLIMEYCELGDLSLFIKKREKLATHPVTCEMARKYPSVPNAGLHEVVNRHFLKQLASALQFLRQGNFVHRDVKPQNLLLLPSVQYRATNKEAPKILSASHDSLIPAAGLESLPMLKLADFGFARVLPSTSLAETLCGSPLYMAPEILRYERYDAKADLWSVGTVLYEMVSGKPPFRASNHVELLRKIENAEDQIRFPKDCQVSSDLKSLIRALLKRNPVERLSFENFFNHPVVTGSIPGLVEDDIPNVPRPASRDARAASKTDEPQPSPSRTSFLRRHRLSEADAGREEGNPPSPREKPLRSSPLASPSEFPGNDEPARGAPQVSSLPRDDIAPGLGIRRPQAIPSTSAPNRPALLEDRRRRGLSNASLSRYQRDDEPSPPSALREYPYKSKGKSAAADERERAAQEIAFERDYVVVEKRYVEVNALADQLAAQGAQAGTSSPKAGQIVRRATQQGVPTSTTGAIPAERSKALQIAQGSQRPDHYRRGSYDKNLSGSPSSTTSVISKAIQDASLRLFGFKYPAHLLGKGTSPPLYNPFPTYPTPAAPAGLLTDGRQSGVLDEDVRIAQGIEDYATRSDCVWGFAEVKLKQLMPLTPSSNRTLGGIPADEVHTDDDDGLTVEAEVALSEEALVLYVKALTLLARCMDIAGIWWTRKGKGDGNTPAYVTRDSPTVQTSAVRINSAVQWVRKRFNETLEKADLVREKLIQAQRKLPEDHPSHPNNHHLGSASMGTSGADGVMLTAGLSAEKLMYDRALEMSRTAAINEISNEDLQGCEISYLTAIRMLEAVLDNDEGLTPRKLAGGATTSNADVVAREGASEIDTDDQEAVQKMIRMISVRLSSLQKKLQIIANASKAEQQGLGRKRSGEIMPRSVPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X295</accession>
    <name>A0ABR1X295_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672434.1">
        <property type="nucleotide sequence ID" value="XM_066808816.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041876"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="131" mass="11335" checksum="50480D8A00F3BAEA" modified="2025-10-08" version="1">MAEANYPSQGWRAGWLDGRRRKRRALGSLLGGLMGGGAKAGGGALAGGAGAGAGGALGAVPAGAPDGAGGIGSKMGDLTGGLTGGAGGSGGFGGLLDGLKGGLGGGAGSLAGGAGGKGGVGAGAGAAVAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X309</accession>
    <name>A0ABR1X309_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672699.1">
        <property type="nucleotide sequence ID" value="XM_066809081.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042141"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991:SF12">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="565" mass="63324" checksum="A9FB22A9D66E70E0" modified="2025-10-08" version="1">MTTHYANTYWPPYHSSSASSSVASGDAGDHHEMEHMHHGGVALVESQPGPSSSSSSSSYHPPPPTTHITLFSMAHATEAMDTQLDTDQDDFDDSLSLGDDDNMEAVSAAHHMAHTQQYTLPPILPSQLHELPEYLQGPLPPGFFIDDVTEDELAEQLHPMPISNANPLSLAPENLNFVDFMRIWAENGRGKLPDIRRLRAQLGDVGLGSTRVEYNQLHGNKCDLQGIDWEDLGVPRRVARERRMMTYRNYTNKSGSEEWNPNLPDRMLRPSDNYYRFRNMSLRRDICLLHFQLRNILGCASRTRAFFPSHGYVKEIDPTSGRSRKAMDFDTEGDMQVSTLTATNDILMVGCFNGDYRFRSLHSENLSYTEGRLTDHLSGITNHVQVYPCRRPDKRLRVMVGDCVDVTIADAETGETLQDLEGHRDFGFACDWAPDGWTVATGFQDKSPLAVLRMEMSGARSLCFSPLGSGKRVLVAAEEADVVNIIDALTFETKQKIDARGGLMSLDRCDAGAEDSYSYLADEENRQDWSRRVPKRHEVSGPLGAFETVTHRRRRALVSGNLDPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3A4</accession>
    <name>A0ABR1X3A4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672781.1">
        <property type="nucleotide sequence ID" value="XM_066809163.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042223"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF63">
        <property type="entry name" value="GLYCOSYL TRANSFERASE CAP10 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="191"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8089887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="558" mass="62219" checksum="89FC1F3AE0104523" modified="2025-10-08" version="1">MGRQRMMISKTQSIRLRNVTIASLALLVFYVFLLHPADQNLDSSRATKAKFNDFPGASYGSGSGSGRGSSAKQKPPSWQKLSPELLNDRFMNSQQCASTFPGLTKEVDDVVAKGSFTLTKTSELGPLIARIKDGKVGYQGFKNVLSEQKRPWLYILQAGRRNDFSDDMLQHRAASLHQIAAALLTAPHPSEIPDDTVFALNYRDEPTESTFSYSRPADPALHGKPGRSYFPIPHFSFWSWPLPFIGSFSRAAAAIQKLEEGADGKDTSTVTPLSWRDKDSRAVWRGTAHFNNVRAGRMRQELLRTAAGKPWSDIAALQWTTGATNASNALAIEDFCRYRYVVHTEGITYSGRFQFHQLCASVVLTPPLAWMQHLTHLVRPVFSYDLPSLAAADDGDDKSSSGNTKTATATIERKLRPPKEYGNGVHEKLSLAPYPAPWVQQAWPRSYTTYHNRHSTAKDADVADDEEGPNIVFVAPDWSDLESVVAWLEAHPRAAEGIARRQRALFHGRGYFSPAAEMCYWRAALRGWTRTVRYEDGLVAALGDGVPWEEFSLKEIHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3G0</accession>
    <name>A0ABR1X3G0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672854.1">
        <property type="nucleotide sequence ID" value="XM_066809236.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042296"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF12">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="192" mass="21320" checksum="01BCA825F32B9265" modified="2025-10-08" version="1">MHLGFALPGVLTPERSPRQVESGAALETFKVNTLGPLMLMKWFADRFLPRKGTELLLPSPSSSSASSSSPPAQLSLPPHATWTTLSARLSSIADNTLGGWYSYRASKAGVNQLTKTLDLHLAKRQRHAMALAYHPGTVRTDFTREFWTHVPEEQLFGVDYAVERLVDVVVAQARLESHRGKCWDWKGEEVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3N5</accession>
    <name>A0ABR1X3N5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_004962</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672895.1">
        <property type="nucleotide sequence ID" value="XM_066809277.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042337"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047_YjbQ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YJBQ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615:SF8">
        <property type="entry name" value="UPF0047 PROTEIN C4A8.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01314">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045319046" evidence="2">
        <location>
            <begin position="24"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="187" mass="20919" checksum="DAACB9C06D42C375" modified="2025-10-08" version="1">MPSSTEHLLTISLLLLFLRPAINDLHQHRHRCPTTTRHYHYHVVVAKAVHPPPRSRGSYLVTDHVVENLPELRGYKVGLLNLFVQHTSCALSLNENWDDDVRADMSDALDRIAPEAGPKGQDLYRHSAEGPDDMPAHIKSALIGASVTIPIKDGKLATGTWQGIWYLEFRASKHSRRVVATIQGEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3Q5</accession>
    <name>A0ABR1X3Q5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672883.1">
        <property type="nucleotide sequence ID" value="XM_066809265.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042325"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF210">
        <property type="entry name" value="ZINC-REGULATED TRANSPORTER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="113"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="284"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="113"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="510" mass="55377" checksum="C679A18F92EC2660" modified="2025-10-08" version="1">MCLVAGIACVFGASIIFVDKLVRLFPGKRDFSIQENSTFLACSLSLSFGVMIFMSLYSMLPEAKSYLKKGGISEQASGFLLMGCFIGGFVGIQVLSRVFHQFLPSHVVDCDHSHEDPAHEGHAHAHDTTRRQSRARSSDKHREVPDGYLANPRVSSIGANGHATESSPLLSTETRVNGQPAGLARPGTGASDTMVQPFPNRAMRSKTTTLERRPSMLQVQKRVMSFVKDTKANCDESGPCYGYSDPCGLECFKHLSSRTVSRASTLLRTATGSFHPGAHDMTRLDEHDGHEDAHSVALASPSCRTSRTHSRDSHSHPGHCEVLEHCSERGDGASVHSEDLEAQHHHHVAENAFLAIGLQTSVAIALHKFPEGFITYATNHANPGLGFNVFLALFVHNISEGFAMALPLYMALNSRVKAMLWSSMLGGLSQPLGAGIAVLWFQLAKRTNMTPTPVFYGCLFAMTAGIMASVALQLFVESLSLNHNRNMSIFFAFLGMSLLGLSNAFTSDAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X456</accession>
    <name>A0ABR1X456_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfd2/YDR514C-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673080.1">
        <property type="nucleotide sequence ID" value="XM_066809462.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042522"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040151">
        <property type="entry name" value="Gfd2/YDR514C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048519">
        <property type="entry name" value="Gfd2/YDR514C-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083:SF1">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21762">
        <property type="entry name" value="DEDDh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfd2/YDR514C-like C-terminal" evidence="1">
        <location>
            <begin position="43"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="213" mass="24367" checksum="8D774122403A44B1" modified="2025-10-08" version="1">MRTDDVISTDAVFVSLDLEFDEWRKKLWALNREPKVGQIGFATSRHALRNIVLVGHSPGYDLSFIRKLGIDITSIAPVLTVLDTHSMSRCLFYPYDRLLPFAHGDDFSLAGLLARFEYRPARDRFHNAANDAEYTLHALRLMAIKSGEERRQEMSPVELGRLWKLEKIVPWWKNGEEYPVRLSEGLKEAVTRVLTCQADGDGSLSDYELPPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7Y4</accession>
    <name>A0ABR1X7Y4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673568.1">
        <property type="nucleotide sequence ID" value="XM_066806272.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039332"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050345">
        <property type="entry name" value="Aliph_Amidase/BUP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674">
        <property type="entry name" value="NITRILASE C965.09-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674:SF12">
        <property type="entry name" value="NITRILASE C965.09-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="364" mass="40017" checksum="CBDC3EAB5E6AA9D6" modified="2025-10-08" version="1">MDAPRLITIAAAQMAGNQLTDTRTQILDRMLALMDQAAEAGVRLLAFPELALTTFFPTQHMTDPEQIAQYFEPASPADPYAVLSTPHAKPLVDKANELGIDFYLGFAERWTTGEDGEMATTTDYNTTIYYSVAAKKGIAKYRKVHLPGTIEPLEDPKAFQQLEKRYFTPGDLGFQAFRAPGLVEGALKADDVGPDTDPKSTVGKGDPILGMLICNDRRWPEAWRPYGLQGAELVIEGYNTTAWAPQYPGTPAEQQSLAEFHHRLSCQAGSYQNGLWGLHVAKCGDENGQGLIGGSMIVDPLGRVVAEARTADADELVMATIDLALCRRPRDRVFNFEKHRRLEHYGLAGRQVGLEEIPLLGRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8F1</accession>
    <name>A0ABR1X8F1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673721.1">
        <property type="nucleotide sequence ID" value="XM_066806425.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039485"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046262575" evidence="1">
        <location>
            <begin position="22"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="156" mass="15000" checksum="5A19502405CC07C1" modified="2025-10-08" version="1">MQSFILSSIVLLCGAASGVMAAPSAPASSNVTVNTIGTNGTASNGAGSLSASGSLAPFGDIGVGCGINWAEGSSFGGGLQAGSPAFGLGGGYTISTSNMTIGLGTGNVKTNTKADLAFTLGYDGAAEFKITYSGKLSCQESTDGTGASVFTCTGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8T5</accession>
    <name>A0ABR1X8T5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucose-methanol-choline oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673801.1">
        <property type="nucleotide sequence ID" value="XM_066806505.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039565"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF210">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="520" mass="55865" checksum="7159A9FB8A4358B7" modified="2025-10-08" version="1">MTKSPPSFDYIVVGGGTAGLAVASRLSEDEAVRVLVIEAGGDHGSDPLVSTPGALVGQFGNPKYDWNFRSVPQEALNGRSVNQARGRGLGGCSSLNFMMWLHPSRASLDAWAKLGNPGWAYDDLAPYFKKVCTIHPPSEAATVMAALGAPTTSAAILRVAPAPRLRTSATELTADPRTGKAIGAFQNPASIDPKDHTRSSAAKAYFGPQVLQRPNLTVMTDAVVKRIIFEKDAADCSLLAKGVVVLQSSGGDKEDEEEEVTISVESEVILAAGALQSPQILELSGIGDKDLLEKHGIEVLVDNPGLRGRRWRPVGRRAAGPRGPGRARGPLPHDQRGRALGQSNISTAYMPLVSEQGGLMSAAEKKALLDAHLASEKEEEEGEGEEYQVLRSFIEPQDEPTAQYLLFPGQITTDQHPDSAASLLIPRAPQDFATVVTCLNHPASRGSVHIASPDVRVRPRFDPKYMSHPLDLEVLARHVQFVEKIVATEPLRSSFKGEGAGGPGCRRDWWAIRSSRPRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8U8</accession>
    <name>A0ABR1X8U8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">15-hydroxyprostaglandin dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673816.1">
        <property type="nucleotide sequence ID" value="XM_066806520.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039580"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669">
        <property type="entry name" value="5-KETO-D-GLUCONATE 5-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G03445)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="33622" checksum="C8E91AFC954B55E9" modified="2025-10-08" version="1">MGSYVADQRKVVIITGATSGIGRDLAHRLHARGYNVALTGRRVPEGESLAKTLDPTGQTALFAECHVESYDSQKAVFAAVWRKWARVDALVANAGIVDKESRYGLARRAGASVDDVPPCPDLGCDDADFKGVVYGTQLFTHYMRHNPPGVKGKIVVTGSIVAIYPCPTFPEYCAVKAAALQWVRVMAPMLLLKENITINTVLPNAYDTGIMPDFQEAYLDEHLTQKECLMSAYDVFLEDESHTKNGQAVETAFDSHYYHDVPAYKSGIVIERTDKVYEPWFQWMHGEKSGLPGAYKEPLRRMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X905</accession>
    <name>A0ABR1X905_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Wings apart-like protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673931.1">
        <property type="nucleotide sequence ID" value="XM_066806635.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039695"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="697"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="846"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="727"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="758"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="785"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="846"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="893" mass="98359" checksum="B737F6FE2A0890CB" modified="2025-10-08" version="1">MDVHKTPQPSRHRISRATATKPDRPQPWTASRCHRLLRPLLSRLALLRKELTSLPEPGAAAVAVATDLPTTKDGRRKSGGKRQSSDCQWMLPRKKMRHTYAQQQQKSAERQASSSVSGGSFSETTQQPLSIKLRAARELQVADEGLPAPGEVVAFTPLVRRARGQEVPSPAKVSQFRGSQGSSSSHARRKKTGASKRGELEDRLASLKGLVSASRYSDYESIFRSLEALLKGTAQEQEKTKGASSLLDMCLKKMPWYIAGVQAWELDEAEQNGAKSAFNSSDTSLRLYNELETLGASGHGWSHLRTVARADGITAVREAMLEGLLNDDFCMLVIDLCTEYEATAEAEVQIEVLIQRQYPSPSGPDASFAENDTLRPLSFLWNFSLGFSRHSFLLRQYTTLLANGFLPVEWLVTGVSSEFGGWLIGSSGHRFLVTAIISLCRHHRASQKTEAHAQLDLHIIPTISRSLAILSAMNVVGEMATRVGELQPIISQQNIAFISQNITYTFFGCLMEVEGRKRRSSNMTKDLLYLAAFLASSSSLRTERVHSRLTSAFELSLGASPPNGGKAVSTHDSVQHYSGMISLISQIAQICGRGSSDAPYQHLERLCRDLQLLGLEQDIINSITRAGALFLAQQTSNLRDLVYAESLVSAHHQQLEETANEGHRPKQQAATTTDLLLGYRWEETIGEWVAASPVAERRKQVQHRRSGRFQQSSSTARKAASRDISPLPSTTARPASPSVQTEPVPDLFTNSDGEEENDSHHGKAGNERRGQSPDEESQRGRRHQTLQPKQCNLLKPTSSNRRCSMRPTAKTTMAAGAGYDDELAWVGGEEKENFEAQTAAATTVRSKSKSKAATVRHHYTTSSSGSHRRPLGEKRRVRLSGDLIIHSDDELGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9J8</accession>
    <name>A0ABR1X9J8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674061.1">
        <property type="nucleotide sequence ID" value="XM_066806765.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039825"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="236"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8092089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="385" mass="42158" checksum="3A57D20A371E19F3" modified="2025-10-08" version="1">MFANHARSQHAFVEPHAPLPRTSAVGSVSPEAPSNTLPLSSTNSSMERSAEYSQTGLPSPYPSNFGDTQSEVSSADHASAAAYPSAQEARSANYSTSATPTSSEYGGGVFPQSARSSSFPEHIQRTYHPASNHSGSSGGMAQTPTSPSMPLPDGRNHQSQQVKSDNELPIDPNITAPSPTYPHQQYSPYGAPLRGTCRTAMLRVYGTHQVYSFVPIPGAQQHKRPRRRYEEIERMYKCGWNGCEKAYGTLNHLNAHVTMQSHGQKRTPEEFKEIRKEWKQRKKDEEQQRKAAEEAERQRQSHSSAQVQNGAAEGADGAQPPQPYSAGRSVHLPPIGYTPQYPAPPSAGVTNVPEYSPTNIAYPNYQQQPASPYAPPNPQMYSQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA70</accession>
    <name>A0ABR1XA70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dual specificity protein phosphatase PPS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_000290</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674378.1">
        <property type="nucleotide sequence ID" value="XM_066804605.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037665"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14516">
        <property type="entry name" value="DSP_fungal_PPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053239">
        <property type="entry name" value="Dual_spec_PTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047949">
        <property type="entry name" value="PPS1_DSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47550">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47550:SF1">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="518"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="586"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8093605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="702" mass="78142" checksum="EC6763E17D411490" modified="2025-10-08" version="1">MATIALPRPIAPHRSSSGIVTLQSPITIDTINTQQQQQQQQQNAATPVPNKHIPVCPTGPAPVQEPNTPPPSPAREDECRQLSLLHPPDKYTHIESGSLSIYKINAAEVAAALDYISRQPLPDPSLVFPWLHGLHPNNHIQQAFFIARKRALRRTPCCLRGLTIVKADGDLSASRLKGAIAPSELLQPGVEGEFLDVDPKDGFSVRNFQIQSAKAAMTADIVVYGEDAAVVRKVGWELASAQAKWRKKHLDQGHDLPVYNTFICPASFKTFELKHSEIVSIDSEGHLTGNVVDFFHQERAEMYAMTKASEISHNVWLGPTPEPASDEEQQFDILIECSDLGRLNPGALKAIAEGPDEDVKHPYLDFPSSGSILPPTWSHAEADGILETCKWIWHLSHGTLPPKSDYDGDMDMDGGPETRTILPRKVLLHCADGYTESSLLGIAYFSYSTGRAVPHAWLNLHTTMKRNFFAYPTDVALLTSIAPRLLRESPLCQDKSLSEITTLIQDEPKWMASLDGSFPSRVLDYMYLGNLGHANNPDLLRAIGIGQILSVGETAMWRDGELEEWGPENVMVVQGVQDNGIDPLTDEFESCLEFIERGRSKGTATLVHCRVGVSRSATICIAEIMRELDMSLPRAYCFVRARRLNVIIQPHLRFAYELLKWEELMHTRRVAEKGEGDFGVKRELEWADIAREIALMNRPYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAF6</accession>
    <name>A0ABR1XAF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674404.1">
        <property type="nucleotide sequence ID" value="XM_066804631.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037691"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="204" mass="23117" checksum="6AADB77B3138AFCB" modified="2025-10-08" version="1" fragment="single">RRTRLSSTVAKPVVMNSESIKIVLLGDEKVGKSSFLARMSKGSNALEGEVEIAPLRDIDQPFVFEARRKNAQFRFEFYDTASPENWRLLRPDVAIICYDISQRLSMINMQRVWINEVRATYAEIEAHLPIIVLGLKRDLRSETDPNGIIYPQEAYRVSQEMRADKYVECSSVTGELFKLAFEEICSTAMKTKTADGGQSEGGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB43</accession>
    <name>A0ABR1XB43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674652.1">
        <property type="nucleotide sequence ID" value="XM_066804879.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037939"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="837" mass="94585" checksum="2DF7AD9050560C51" modified="2025-10-08" version="1">MATQKPTSIKQLLPDIIWLILDYIDEDNFSVAPCATISSVWQHSVESCAFSSIHLKSTSEVSEFRDAFATTHRRAYLRELILKLHLLSNCRRKQGRIKNQLVFRQAVKLLLDVLSEWENIDGRGNGKLSVIIEPVYDRYHVYDKEYNKRSLREVTFGPSKALLDRKFLALWTEGEPVMLPEIPCVTGFVTINSADFVRNYCDPAPNYRNLRQEHRTAFARGLDSLCGHLPRLKELTIRCFPEKNHPIRDHSFRCQDFTDSQGVDLLCEAIRKLAQPTVTHLTLDGGMVSSDLFHSQRTGSPDAQGDAWHSLQQLDVIAEWVSPNGSWYITGLKESSEANQSATAQIESVPYIKGAPIDEWDSGGQMNASLNGQLGNYWRDKLDSATVEPLLSAWADTLVHRMPCLQVGTLRMPGFPDPASFFAGCAEAGQQFPTDQWGGDVPARSPRRHWCIKWSNVKELLVGTELQRKWKAWVGFLALTTVLNSQRSYGSLPRSYGSRSDFIPSGLANSSASVAIPDGKSNGVRRYRRFVPDWARKQWRRLRPLKPQPKPLWWLRMQHNLVLSPLHRLPEEIMLEVCRDLDGFDIYIMQFEEPFRSSAVQPSATCLLPEVIKLPVHLEGTATQDALCVQWTIPLRVKAKAAVAAGMTTLYYSICQRESHGAEKIEEALSQAAEAGYNNLLCPHISFDDLLVFHDFVRAAYGAARDFEDGYTWKSELDPTEGFVQRYNDPHALTDWFHGMCRVLRVSLERRRTGPFTSTAAEIVRAGPDRPVVHHARRLATDAKPSVVRADDRCGPAAHNLLSRQALRQWQVVGHAPKTLGHYYGAFQGEKVDTITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC41</accession>
    <name>A0ABR1XC41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000886</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674974.1">
        <property type="nucleotide sequence ID" value="XM_066805201.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038261"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF152">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE TOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="180"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="109"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="371"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="705"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="930"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1123"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1181"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="726"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="774"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="815"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="831"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1034"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1058"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1185"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1207"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1236"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8094201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1245" mass="137874" checksum="AC5A15169339C287" modified="2025-10-08" version="1">MEEEKQGLASWVAQRNSTPGWMARMPTHQRQDPSSLLDFKNETATNAFPQALTSSPTRFSSASERFDDDAAEYLPHRNGAAINFPTGATAPSKHKDRIPFAIPSPLPDCEQHPVSSPGLFSPNNPRPALNFPTHSASDASTPVAMNSPYLHPLQNHRVRETHKALVDLDSMTGRKIINQYEVIEEIGRGVHGKVKLARNLENGENVAIKIVARFSKKRRLGKVMALSPQDKTKKEIAILKKIRHPNVVALLEIIDDPELKKIYMVLEHVELGEVVWRKKGIPSICNWERRRIEKEMSGEMSTEEEEAYVQILERKHAVTELKRARMQQKQQQRGPEDFWSIEYGAASEGGDPSSLPRVLSRDAVQGSSAGEWNFFSASPHGSRSTSRAVTPIPSETDLSSVGADYSSDMETPGATHSRPCSVTALEGTMYGPYAAEEAMFRGRSPSMADSIISHMSSVDFNTQPHDPFADDYSYVPCFTIEAARATFRDTVLGLEYLHYEGIVHRDIKPANLLWTKDHRVKISDFGVSYFGRPIRDGEMDEFVSESEARDFDDDLELAKTVGTPAFFAPELCYTDVESTDDVYIPRRRLKPVDPLTSPTTTSLYHRVNNAPYRDDCEFAYEEIDDLLYDLLSRMLIKNPEKRIRLREVKRHPWVVQGIDNLLGWLDDTDPSRRTAGRKIQVDEREVSRAVVPLTFLERARSVMKKAVGKVMPSHRPDATVTRRRATSSAASSAGDSPPTAAASPHFRDSRRKSLRGDDYFVSSKEPAGHHEHPLSQSVTASPQASPPVDDQEDRNALKHSQAHSSSVGGDLKGQATGSHSNFNASPDAANRSPSRKTTSPGKTFSPSHIRARSVNSQFLVLTAAGRESQTTPATPAVSTSCHDDPLAALRKSRDMESLDDSSRSRSVDRGLFAREDKRAEAKVSLSTAIAPGNVESPKRPTHLRMTDPSTHNGDPQRRHPCSIRRKPSEPTITSHPVLQMDAKTPPQRIYKASTPESFARAQEQMQRRQHREHEEQVRRQQLQASQQDVNPAWVPCPPSCPPSPDDETRMGKPLPPSRSDTAGTVVTTSSSYGNMATPLTSPSEAASPVRKSDSPIYRSDPSLPALLSGASSVSADAEGDFLLRPGSVNRPSLIDTTDSLTPPAMPKEPMAGFPLETLEDEHAFHLRMANSTHMRSSSVFSSQCVDDDDSDSDEGVLMIKPRRRGTSQDPTSQPLSRSNTHIKRRDTQTSVGSTETAKKVVMHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCR8</accession>
    <name>A0ABR1XCR8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7704 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675236.1">
        <property type="nucleotide sequence ID" value="XM_066805463.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038523"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056121">
        <property type="entry name" value="DUF7704"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019:SF1">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24803">
        <property type="entry name" value="DUF7704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7704" evidence="2">
        <location>
            <begin position="3"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="153" mass="17049" checksum="7D1F144745AC93BA" modified="2025-10-08" version="1">MSPIPLTYRIIFNYVEPLLATLGAIQVVIAPRDLLRLSLPSVPYSPALYPLFPQMCGAWLMFAFHDVVTLRIYQDVHIWKHILGAAIFSDLGYTTGLVQSMGPAWFFNPLRWDGANAFTVVSTLLPLLAKILFVLGVGLPRPAPRVKVSDKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCZ4</accession>
    <name>A0ABR1XCZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rgp1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675339.1">
        <property type="nucleotide sequence ID" value="XM_066805566.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038626"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014848">
        <property type="entry name" value="Rgp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12507">
        <property type="entry name" value="REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08737">
        <property type="entry name" value="Rgp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="792" mass="85303" checksum="F8784894ED2EDA45" modified="2025-10-08" version="1">MSPDSSSNIRVFIHWNDQTVFAGEDIKCNITFKNVARPIQTSHNTPLDRSRQPSPLLGTPRKPSSNSIGLAPPAATRGRGHRSTLSLNVPASSVRSRNATTQWIPPQPPPTTRPGHAHKRSLSIVSIGSNATVEEQSQTNGVKLSPQRPARGHGRSAIGYVALSAIYWLAGFSHVQYPIIAALKTRPGERGPGQMPEFKFPMISSPLSGPGETSPGTQEEEYNLTPVSTAGTSVTLPVRSRDSIPIITENSVAPAARILSTTSMAGGTPRSSGEFYSMSNNSSETLASEYVTQPLRNGARPPHFRRSSNMSMLGQAKLPEALMMGYAQVQGSFTLDGSLIELAPFEQVKRKAVLGGQGGGVIGIDTPKRDSGLLKSFGWGSWSSSIGELLGAGELSSMKDMRGAASSKSIPLLSTPQTILFVDLNLAPGESRTYEYTFRLPKGLPPTHRGKAIKISYSVVIGTQRPGGTREQQVKSVEIPFRVLGSVNSHGEILGHDLMSPYILLRDAGKSRLLDKMANGFDFPKAEKAPRPNSTMNGFLDYVNELLDQPRNGMGLLSPTAGGPSSRRPSIFEEASSAKEAIDMAIMRSNLASESGQSNNRFEIARNGQRVAVVMLARPAYRLGESVTMAIDFTGAETPCYAIHAALETSERIDPSLAIRSEASVHRVTRKTFGSASEATLFARRIVFNPTIPINATPEFVTSGLSLEWKIRIEFVVPSSSVEDAEGDRRAQGPHPLLEEIARDDRGGLVLVAAENLECESFEVAVPLKVYGAICDGLERLERDEAEEGLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD78</accession>
    <name>A0ABR1XD78_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675429.1">
        <property type="nucleotide sequence ID" value="XM_066805656.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038716"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="292" mass="33250" checksum="2908FDB374FD5281" modified="2025-10-08" version="1">MSDVRARVAEFAPFPVVPFASDYAPFTSTLPFDTGSIATLEPIHEAIPYHLAFYHLHHARHRYPLDSSSKTCFIGDLSCHGTSTIYQNVPCTWSSEIYYSCGTFLQKQELLYTVDARRTIWPQIKIRVCHHKNVRLQYFRVGAEDTHGLITVSLFLTFPPEGRWRGDTGADWSSAWGGNLRDLHVCDKCHSDLEYHVEVVGHKAHVRFTCSRDLGAATDRFLPKWHILQTGAGSYCSRNMQYHYNTIEGRCDNPSTYDVYKRVLRTATKLRRPNLHPATFGTSKGDFSALSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDP5</accession>
    <name>A0ABR1XDP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic type KH-domain (KH-domain type I)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001399</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675487.1">
        <property type="nucleotide sequence ID" value="XM_066805714.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038774"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="167"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="272"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="387"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="86"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="340"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="460"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="371"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="465"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="502"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="564" mass="59148" checksum="BB7A88AA353E50F8" modified="2025-10-08" version="1">MADPSKNIESILAALGADTQCLPPSMPPGVQAPPYAGGAYPLPQPSASGSFDLSAIKPVNSGTVSIADAIAQAKAFATEKGISYDHSRAPSASYQSHDPRAHYRSRSRSPPARRDAYRDNLNPYRDERRDEHRGASREYGRDRSMSPGPRGHFSPRGNNSRDRGGGDDDTETIQIESSLVGLIIGRQGENLRRVESETGCRVQFITGPDNQGPYRQCRISGPQPRRAEAKAAIDRIIEDSGMGAIARAGLDKGRGGGAAAAHAPVPGTLREGEDCMQIMVPDRTVGLIIGRGGETIRDLQERSGCHINIVGENKSVNGLRPVNLIGSREAAAQAKEHIMEIVDSDSRNVNGGGKQDRPPRNDHGRDSGPPSMGGGMGGGMGGGGGGDKINDSIYVPSEAVGMIIGKGGETIREMQSQTGCKINVSQSSGPGEVEREIGLVGSRDAISRAKLAIEDKVEAVRQKNSGGGGRGGGRGPRRDYDNPNYSQSGSNSAPGPSGGASAGQPPAAANGADPYAACKSPTSYIAPWNLTNSLKDGGYQAYLALWYQALAQQQQNGQGEAPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEE9</accession>
    <name>A0ABR1XEE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675849.1">
        <property type="nucleotide sequence ID" value="XM_066806076.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039136"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8095076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="940" mass="105931" checksum="77046B07B35007D0" modified="2025-10-08" version="1">MESPVKVASDFARQFFAQDSGVTLEGIEGSGWRTLRLRLKVNTSRLSFRKYMMHMAFEDPPPSSLERDTLLLQDLQYVIHVVKLVALSNEPTPTPEPKNFKPVFNPFKPDGLKYEHYLIEHEPNGSLEQLITRMEEDEKTYKSSLDTGKDADDRERIPNRLLIRIFLCAARACAAMAWLPGPGRDRFGYLLPEEARNDVDPTNYVHGAIRPNHWLFGQVDGHTEEHSLVPIMKLAGFDEAYVHNGEEADIENTPEFDQKSEIVCRTRPVGKSNAATRVNILNVGVLMGNIILEDNQLLTADEVRKELGPKGQWSRTTHPGYDPELVELVARCLAVEPNSRPTIQELLDTLRTWLFQKTGTYYAMKPGDKWETDVALRQLIQRYRARTEQQVGISECPLSIAYERSHLEGDLPGGRATLQLGDYIALSYEWGDPARTGRMVVNGIEITVTRNLQDALRDTCTKWWDNDDYSEEIHFWADAVCINQLDVSERNHQIKLMGEIYTQALRVWAWTGPGLEYDEAALKLLNEFRVAAVEGPCHCKMCDCIILLGFSNPTDRACAVRRGSPIYCSSCTAGALAQQKDERDKVYGLLSLMDPDIHNAVKVDYNKPYPIVYQEFARCVVEKTGRLDLIYQLAADCPSQGEHRAIGDGASESEYFHLPSWVPDWSSLASRHGSGDYRDPFMNRWKKNAGSHTEHMAQKEAHKSHLTCKGTLLDTVDGLGCSRDARLRHNGHDIITPTHLSNASPVTKDPRMMKNAVWGTITMGTVMDGDTVNPKSIGEVLDFSNLHDDNCIGDDGMVDEIMSPAESRIIQWHRCNQLFEVFGLPLHSFFEELPPKAYRKRAISSATETMYLHGVLANVLAFRRIVTTAKGYVGMAPKTSRQGDSIFLLKGCDAPLVLRLNGDGTYYLVGEIYVHGIMDVEAMDQFLQDGSVEEMDVVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQD6</accession>
    <name>A0ABR1UQD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA binding regulatory protein AmdX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_015342</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660541.1">
        <property type="nucleotide sequence ID" value="XM_066819656.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052716"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF13">
        <property type="entry name" value="RESPIRATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="50"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8061121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="276" mass="30326" checksum="D3941A2A2758EEFA" modified="2025-10-08" version="1">MGPLSADAIPLLDLAYVRLFVNLSRSKEKFWQRDWDGLAEELSRGNEIVQHAEHSPESNNDSLNETSDASATSSVFIDSPPTQSSSPDFSTAKFPPPMPAPQRRQSQISSRAISKREKHLRKAAFYAADSLAMADKLGVTLADFTSRELPMQSAMCAFDCAQVLAEWVATLQDRVGRYLGIIGQDEVDLSQVPAIMLLEDEDMKLLSKVQEVLASAEMKVNLDLVSGNVSSGMVQMDDHNGYAAKVLRLTAYMLDKSAVWPSKLFPLLVAGSAFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT57</accession>
    <name>A0ABR1UT57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Oxidase ustYa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660716.1">
        <property type="nucleotide sequence ID" value="XM_066818528.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051588"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="30798" checksum="00E9D7FC91A80760" modified="2025-10-08" version="1">MEYSKQPGGYQNVALGDDKDEGRSSTEVDESVMGDEKHWRGNYHHECQHHSHEKESTTRKYMTRFRRYRWIVDTLLLCVNISLSLLLVRDFWREKSVSRIQVGGDVTGLGPDFPTKIVKFNADEAFVPNDTSKFFSNETIAQWNTMLPIGSGWGEVTDETFFTTSMTHQLHCVFMMARIYASLEGNTKERLPSDYHSHYLHCVDYLRQGIMCSGDLAMEPHDQSDSDDNGPLDGSWNGHHVCKDYNHVIPYLEEQIADGIRKVLPIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU42</accession>
    <name>A0ABR1UU42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">ATP-dependent rRNA helicase RRP3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_014544</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661046.1">
        <property type="nucleotide sequence ID" value="XM_066818858.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051918"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17954">
        <property type="entry name" value="DEADc_DDX47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044765">
        <property type="entry name" value="DDX47/Rrp3_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF20">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="124"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="307"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="10">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8062447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="60959" checksum="8A888D729D425433" modified="2025-10-08" version="1">MSSMTGKRRKLSHDAKAPRAKVDVKSEKKKPIAKQVKDEESESSEEESPLESGTLQDEDEDEDKAEAKEAGSSSDKSEAGDDDAEEDEEVLNKSFKDLGIVDSLCDACEALGYTNPTPIQQKSIPIALQNRDVIGLAETGSGKTAAFALPILQSLLDKPQPLFGLVIAPTRELAAQIGQSFEALGSLISLRCAVIVGGLDMVPQSIALSRKPHIIVATPGRLLDHLEKTKGFSLRALKYLVMDEADRLLDMDFGPIIEKILKFVPRDRRTFLFSATMSSKVESLQRASLRDPVRVSVTTNKYQTVSTLKTHYMFIPHRHKDTYLIFLVHEFSGKSGIIFTRTVNECQRLSILLRHLGFGAIPLHGQLGQTARLGALNKFKAKSRDILVATDVAARGLDIPSVDVVINYDLPSDSKSYVHRVGRTARAGRSGHAISLVTQYDLEIWLRIEAALGQKYNEYDSNKEEVMLFKSRVDEAAREARTEMKDIHESRDKKGRGLKGGRFKKGALPVAKEDVMIWILRRVDSWLFGAMWLPVMFLALHYEPGNGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUH3</accession>
    <name>A0ABR1UUH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014444</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660946.1">
        <property type="nucleotide sequence ID" value="XM_066818758.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051818"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="98"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="236" mass="27312" checksum="9B42B404F542DD1B" modified="2025-10-08" version="1">MPAKVSKSHPQSPSKKQKKQHDHDLREPHELTSESTETTGEDKQDPYPNGTNHESTGLHDTTTTHEDEEAEKSKEGCEWRDQPPYRTEGKNEHATKHHEAQCNCGRIKYWLSREKPLVSKYCHCAPFQWAAIFKKEDLHFENGAKGLAFYHAQKKHTYHDLPCKVSCAYCHAPIMDEGRNMVLMFPAIIKFKSEKAKKDFQPTMHIFYSRRCLDITDGKTKWAELDEKSEEIPETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV17</accession>
    <name>A0ABR1UV17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661367.1">
        <property type="nucleotide sequence ID" value="XM_066819179.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052239"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="516" mass="57765" checksum="781E5AB40E195098" modified="2025-10-08" version="1">MFLASMENPLRTVLSTISFLVLAALAVRVVHMRFLHPLRRFPGPWLRSISQIPTALDLLRANQPMVMRKLHEKYGPIVRLAPNELSFIDADAWEAIFGFQKNGPNFEKSELFIGAVNPLNGSVGISLAPNEIHTRQRKALAAPFTNKALLQQESILQRHVDKFIAAMKTMANGGQAVNLADWYTFVTFDMIGDICFAEPFGCLDTGASTEWAASICNIFKSAVYDQAIRRLTKTGSFLHKILLKLIVPADAARWRQVHFQNSKEKTMRRLADPDRDHPDLIKHILDNEDSRKALTETEIVLNMVLFISAGSETTANLITGWTYFMLRNPAKLARATAEVRSAFATAQAIRWEGVKNLKYLDATIHEALRLFSPAAANQMRVVPAGGATVCGHFLPGGTTAGIAPYAAVHSPRNFSHHEAFAPERWLDGGDARYAGDRLHASQAFSVGPRGCIGRNLSWMEMRLILSNLLWHFDLALDEERPAARAALRKWDEFDIESYATWMKPDLQGFGHIKRCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1N1</accession>
    <name>A0ABR1V1N1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011858</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661865.1">
        <property type="nucleotide sequence ID" value="XM_066816173.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049233"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001931">
        <property type="entry name" value="Ribosomal_eS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018279">
        <property type="entry name" value="Ribosomal_eS21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038579">
        <property type="entry name" value="Ribosomal_eS21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10442">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01249">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002148">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00996">
        <property type="entry name" value="RIBOSOMAL_S21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="87" mass="9595" checksum="346EC09803444FC6" modified="2025-10-08" version="1">MENDKGQVVDLYVPRKCSASNRLIKAKDHASVQISIAKVDENGRAVAGENHVYALCGFVRAMGESDDSMNRLCQRDGLVKSVWSAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1X4</accession>
    <name>A0ABR1V1X4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GPI anchored dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661922.1">
        <property type="nucleotide sequence ID" value="XM_066816230.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049290"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03457">
        <property type="entry name" value="intradiol_dioxygenase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF2">
        <property type="entry name" value="ANCHORED DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045832859" evidence="1">
        <location>
            <begin position="22"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="367" mass="40339" checksum="259BCB102E65D09C" modified="2025-10-08" version="1">MPFKLLTTLAVGLSLSSIVASHPGEKFDKRAHMEELANGHAVADVNSRALEACQNRPEVKARKERAIARRAATFDRLRQERDLSDATFLHRRDAASFRKWAGQSHDFTGKLSYDKNTPIEEIFGANTSCTLAPDNANGPYFVYQEHLRQDVAEDLQGVPMHLELQFIDVNTCAPADLLIDIWSCNGTGKYSGVSAATQGGLGTTFLRGVQPTDGDGVVNFDTLFPGHYEGRSTHQHIIAHVNSTVLDNGTYTGGHVAHLSQLFFDQALRDAVEATAPYNTNKIPTTTNLRDMFTGYSASPKYDPFANYVALGEGLDKGLFVWAELGINTKANWDYYATYASVWKEGGGYNNPKFNMFIVGTPPPTHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2C9</accession>
    <name>A0ABR1V2C9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661846.1">
        <property type="nucleotide sequence ID" value="XM_066816154.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049214"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="112" mass="12162" checksum="8C0F5562AFE1DB1C" modified="2025-10-08" version="1">MPPFTPHGSANGDEYNEEYFMNCDFDNNGIDTDYQNADALSRSFSSSDAGPDGSDDSGDENENENADGLDAEDEEEDPDESNGEGSLGSRFSRHSSLAFSCFILIDSARVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3S8</accession>
    <name>A0ABR1V3S8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662605.1">
        <property type="nucleotide sequence ID" value="XM_066816913.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049973"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37015">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37015:SF2">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="967" mass="109437" checksum="5595244FE6D78D29" modified="2025-10-08" version="1">MASSSGSVFSETLKEITDTKLQELSKRRAAFEEKKSAILSSLNDHDRIKRLVTLSAGVKSCYAIKLDSSGRIADTFAKHTSLEVELKNLDSFIAQARYDPSVSTKTLEKWETSLLGHLDTMSLKYAYASLYAQLVTEWLAPESPSDPSSGPSGAGDDEEMTEPFETVESAKRLEAKQQWEQDVFVPAQVDEAKLTRFLKELFVNEPADSSKKAKALDKLAESIKDFEYKLSVPNQFNAYTLKWVIEGLLASDRLSNEKREALRDFVKNDIILGEIADVLNMRLSALDAWSWGDNVPLEQRRKISGVYSVHMDEELLQSIFLQYIGVKWSVFFKRAFKRFRRIGGPWADVRQPIPELDKLRREYYLEDGVSKWQNDSVQHVRRSMHRKDYFMARLLDKESQQVEIVEGEVEVEHYSAASPVAMVASVAPKRKRLASKAARKSAPSTGMRSVPENSETDSDREPEYAKKNPMQTKQRLLHILSTEATVCSSIHNDFTALHSSFDRWDSLLPHTTIHTILSFFGVSDTWLRFFAKFLEVPLRFMDEPANTAVRTRRRGTPTSHTLSDVFGEVVFFCLDFATNQSTNGSLLYRLYDDVWFWSASHETVVQAWATLQKFAAVTGTQLNTTKTGCIRISGDPDITPAIHSSLPRGDIQWGFLKLSTQTGRFEINQALVDSHIAELRRQLQTKKTSVFSFIQTWNSFANTFFASNFGEAANCFGRSHVDAMLETHSRIQREVFRAGAAGEVEANSVVEYLKALLCQRYGVEEIPDAFLFFPVELGGLDLQSPFVSILQVRDSILADPSSLMEAFKKAEVEAYRTAKENFEELDPTDRHHSWVPQGSGEADTFFSLEEYARWCEELWYSYDMELVDVYRELLKRPGHGGGIEMDEAGVVASGLAALGADGSYTNATLRSGIKSDWHSMQPYWRWIVALYGPEVVARFGGLRLVDPGLLPMGMVSLFREKRLSWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3U8</accession>
    <name>A0ABR1V3U8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662617.1">
        <property type="nucleotide sequence ID" value="XM_066816925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049985"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="53"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="311" mass="34213" checksum="1438B96BC05C49CF" modified="2025-10-08" version="1">MAAKGVIELPHIGIRAGYELSNGSYDSSKPTCVLINSMCTTVSLYRDQLSHDKRLTSAVNLLAIEPLGHGATTCIAEHFTYWDTAIMALQVLDALGIQKCFALGTSQGGWIVARMALLEPGRIQGILILGSSMDAETAQTREIGCWDPAPFVRPFIEERWAAAAGGAPTPDFVVDDEWIASIAHLGFGKAATPENTEFWTKTLREVYKGDEGRRRLRMATIALVERDGLLFRLPYVRCPVHWLHGTDDPVYSPEIPKKQIKLFTGSKEAKLDLLEGGAHFLNATHPKEMVEAILQMASKYGQYVNGNTHDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3Z4</accession>
    <name>A0ABR1V3Z4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012656</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662662.1">
        <property type="nucleotide sequence ID" value="XM_066816970.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050030"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22448">
        <property type="entry name" value="KH-I_ScSCP160_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22450">
        <property type="entry name" value="KH-I_ScSCP160_rpt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02394">
        <property type="entry name" value="KH-I_Vigilin_rpt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054548">
        <property type="entry name" value="SCP160-like_KH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627:SF31">
        <property type="entry name" value="DODECA-SATELLITE-BINDING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627">
        <property type="entry name" value="SCP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22952">
        <property type="entry name" value="KH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="189"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="269"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="364"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="679"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="746"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="843"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="919"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1000"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1069"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1183"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="784"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1103"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="344"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1262" mass="137764" checksum="359CA668C1E224F9" modified="2025-10-08" version="1">MATSDMNGEASTSAAERLLQQHAENPLHHVTVEDAPDEDLPSVPSKTASSIDTQSIEAFPELGAPKGKAPVNIAPIWSAKGGRSNGSTPANGTPRASTPASGVATPVGNVPNMSIPGRHVETVTIEPQFILPRNQLKRPIPDVVKDINRKSRAVLTTSNVGNGRLRIDATGPQDKAQQAIRDLVQQIGTRQTIKVPIPRSTRAHVIGKQGSTIKSIQERTGARIQMPKADDAADDDDDDAMVDVLVEGNTITAAAARDAINRITGERSSNVSTKLKSIPAEFYPFIAGANNNSREALESDHNVQIRIPSHQPWAHPIPAIPSAGDRPLFAPANNDNHIQLAGDRAAVAAARAAIERRAQELQNQLQMDQVDIARTRHQFIIGDRGIPMDDFFAETNCVILLPTDDSAEAVTVIGLDQDAITCGLEKAMDLAMSISSSPMDVSRSHKHAAGGASTYSRDVSRYLRQRKEIERIEKLHKIHVTTPFIDGVTSPWELFARDAKNIIKAQKEVSSIVSGLPPSRLATVPVDPFFHAYLRSDVKPKVQSDYGVHLVVPEPGESTFPVLLVYEGETGPEPYQVPQKAPTAQDLKTFQQGLQEARKHILDLIGKQEQLKAETLEVPTKFHEKLRKYIKKEQDATVRSAGDIPVRVSVRGTTVTMRGPTSAVDSLASKSRAFVEQEKEDEKELRLPQKFANHLIGKGGSHINELREKFDVDIQVQNGEVELKGPKAKAERAKSHINSLARTWADETTHTLKVEPKFHRELIGAQGSQIGRLQTRYNVHINFPRTARAGKDGDDDEAAEAASDSGKPKRQQGADEVVIRGPKKGADSARDEVWELYQFLKNNSFIDTVTVQQKQLPSLIGSGGSAMDELRSATGAKIDIPNERNEDENTLVDVQIKGTKSQVAAAKKLLEEKRAIFDDTVTKTIDVDRQWHKILIGPGGSTLRDIIVKAGGPDDRRLQARTIQFPKQDADGNSIKVEGRTDIVDKIVASIEAMVSERASQVSEVVDVPVEKHRTLIGRGGEAKRKIESEFKVSIDIPRQGSGQTGVKIVGKPDDVEKAKEHILSSIKEQEGETVQVPRKYHNAISDNGAFFRKLRNDHKVTVDHAGQPTPPKAKASSARANNGPTPLITDDPEQAAEAHSWNIVDTASTEEGEIPWVLRGNPENVERVKKLIATALEQAQKNTATGYLVLPDPSTYRYVIGQGGSKVNAIRKQSGCKITVPRDQARDEAIEINGSRDGCEIAKDLILEAVREGAASRQQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4I6</accession>
    <name>A0ABR1V4I6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012852</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662858.1">
        <property type="nucleotide sequence ID" value="XM_066817166.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050226"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="3">
        <location>
            <begin position="35"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="361" mass="39622" checksum="0B8E85C3449C2C5E" modified="2025-10-08" version="1">MAPSFNAERDGDVALVGNFVVWAMAVVSGIFLGFRVYIRQARNQLSWDDHALVGGWVFTIAQSAVFAEMLRRGFAKATIAEPTILLLMLIGDNLQKFALSLTKLSFSLTLLHIFPSGWQRWTIVALLLVINSYYIAHLFLVWLNICDLLSASSDFILAFLPLTRMLEVTLKSHDKWVAAVITTSVGVIAGLAGVVKGFEGIRLLDYESSRCAPKTRLPFHLGLPHRRYRRAQRHHRSVFHPDPANLLPDPAGLPRDSPPPGMGPYVASDNAGKFPGGGGGGSKIQDKHQSSDTFSESESKKNAQKQREQERQQQEEAAAEADAPGIMRTRTVAVTYDDNMIVGSPPPGTADIEMLSRSAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4P8</accession>
    <name>A0ABR1V4P8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011791</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661798.1">
        <property type="nucleotide sequence ID" value="XM_066816106.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049166"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049207">
        <property type="entry name" value="DUF4246_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21666">
        <property type="entry name" value="DUF4246_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="3">
        <location>
            <begin position="23"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="138"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="747" mass="84561" checksum="9C3D1E786613BA2B" modified="2025-10-08" version="1">MQDPTTQSQTTQGQQAHQQQHQYPGINLPLRHYATGWSRETMQACYPIGVCENAPGATSELFQLREVFMLAVMDRLTDKPDWHRKVFDDAVVAKWRAEAMQQPEEGLYRLAVEHVNLWREPLEESKLSPLKRSRYMSEKAFDYCIQELRIKAEHFEKTGLVPTLDAVGSCVAKSDVLVKEDLKQEIVAAFDQLRADQAAAGEVDWHPRSNDMVQDLVHPSMYCLVWGQTPFLQDEVVGTTDAVTKWAGKGEPTPDHQKENPSPPPVPNPYSMPGVPDHYWSANFQWLPANLAFRDDGTVRFTSYINNLHPTRYEGVYRTIEKLVDRALPAWEQCLADIQPHRGETSRAGRRYHRISPVAYADDNETDGLWEELNPAVLAQLNVQLDKDAMYELIDELDAELSDKEAVELRAATDDLDLEGDVEGLPRALLDKLPQGRLESEQWKQVREPIFIEPEAFTDVDYAACEKLRDKFGQSGLQVIAKMASIELTPEKPEFPTGSWHIEGQMNEHICATALYYLDSDNVTDSSLAFRMGTSWDQEELMMSAGQDAYNWLERSYGTSFGPTGSGGPCLQFYGSVGTPEGRLLAFPNVFQHRVSSFRLQDPTKPGHRRFIALWLVDPHQRILSTANVPPQQLDWWADAVFSPNNTNSSNSNSNPNSGTMPPEVLALLREKQGLADKLPTPDQQAEASRLPPEIVDMVRQHGIVAAGLMSRAEAEAHRLKLMDERSHFDQRAKDDWFQGDYNFCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5S8</accession>
    <name>A0ABR1V5S8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metal ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013298</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663304.1">
        <property type="nucleotide sequence ID" value="XM_066817612.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050672"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12829">
        <property type="entry name" value="Alr1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044089">
        <property type="entry name" value="Alr1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535">
        <property type="entry name" value="MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535:SF55">
        <property type="entry name" value="MAGNESIUM TRANSPORTER ALR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="583"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="244"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="610" mass="68864" checksum="56DC6DD6D80F7359" modified="2025-10-08" version="1">MSDHEEISERGSGYDTPVPELDDHRHQSASVQRPDRPRRGTVDTLYGTRHLETPPDIRVRDFEEAIADDEADDVSPVRPRSRRPTVDTVNDARSLSPPNSVKAFAEARRRGRAYSTNNKEAEETKEDGEKLHLARTFSGGSRQSLRSYRSVRSKHTVADDAASLGTNRTVEDDVCFPMNDEHRQDRLYIDFDYLENFIAAENAARKEELDAANATKVFPSLQTEQFRSPSPMVTADGDIYQLPPGTGMTDEKQVEETAEKSDGEATKQDPIDPNRFSFFSTAWESTIHAAEFGDLVLPGENVRGLFQFPADVNDGVWWLNMNSPTEEEVRTICKAFGVHPLTIEDITTQEAREKIELFPSYYFACFRSFSVTQEEDGPDYEPFNLYVIVFREGTLSFSFEPNSHASLVRKRITMLKEYVSLSSDWICYALIIELITEGIEDSVFVARADDMHSFLRRIGAVRKNTLGLMRILGGKADVLKGFTKRCNENYKVTPRMDIGMYLGDIQDHVVTMMTNLTHFEKILSRAHSNYLAQLTIDSIAQGTKTNEVLSKITFLASVIVPLNVVTGLFGMNVHVPWQDVENLHAFIAILCSLVGFVLISLLIARKARYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5V8</accession>
    <name>A0ABR1V5V8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663316.1">
        <property type="nucleotide sequence ID" value="XM_066817624.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050684"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="402" mass="46403" checksum="2E74C02B5889DF44" modified="2025-10-08" version="1">MSVSRAFYQEGNFCLNKHESWEPVKASIRSLSAVAAHLFKLKHPFIMVGEAAAFAMNVKWEDPTTVDLLVRASTLEKLKTVLAITNSWTEISSKTRIQSGYRNTQCRRRDACLLFKRNVSRGGPWCKYLRLWTEEAYGLKIDADSFIQIKPTFQLFEKAEQEDPIDERSTIRYIPETYVPTLPALLQATIRSINRGRQDQPYAYVDSLARLRALVKVNWLEEWPAREVVLEQCREGWQYTYLNGFFDSYTRPLPDQDGSRRERSLRLQCRRAARWASLDLYRRTGYDAEEEEPLPPLVPELMDLDADVDVDDRPMVPGSCHYYNSNSDDSDFDSDVDDQVQQAYPMEHFMARAESDKSSDYEAAIRAWHELEKEKSQVDLSPQARTGWEKPGNATRGPWGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V658</accession>
    <name>A0ABR1V658_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663150.1">
        <property type="nucleotide sequence ID" value="XM_066817458.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050518"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="37505" checksum="5CF79D3B1A072414" modified="2025-10-08" version="1">MKVPDRLPANDPNRQRVDREVLEIASPLSKNQKFQHDDSTWLGTWNLGWTVKMSRGEIMKGKNRKVLYQRDRSKYWFKKEEPNVARVDPYRDLIILRVASKDFEITNLDPAKNRKKFRDIKIVGFDFFNPEGKTARGTPWNMDAFFCTCYLRPHRDLAICPKALCEFLRLFGKLRTVFIIYPINKGRIDQKIQQGIGNRGQKRTRDATVIEQTPKFVNKNAETLMEDTMNKFKGIAHERNLAVFEDRKRVYYQVRKKDCKEFKDHHNLWGIVSQFQRSWTKRRPVGDPISDAQWDAWTGVNAILNNEIKPEDERAESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V697</accession>
    <name>A0ABR1V697_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_013464</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663470.1">
        <property type="nucleotide sequence ID" value="XM_066817778.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050838"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF34">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE SETD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="27"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="485" mass="54735" checksum="3C8272AB37E57980" modified="2025-10-08" version="1">MAQPSFDERTQSFLNWFTGLPGATFHPNIQIQDLRQSGQGRGIVATSDIPEDTELFKIPRAAIINTLTSDLTKRIPQVFEDSTEGLEDVNNEADEEGDTSGAPDSWVSLILVMIYEFLQGDQSKWKPYFDIMPESFDTLMFWPRTELGGLQASAISAKIGKDEADNMFRAKVLPVVEEHAHIFYPKGSKRMNEEEMLNLAHRMGSTVMAYAFDLETDDEEPEEEGDEWVEDKEGKLLMGMVPMADILNADAVFNAHVNHEDDFLTVTSLKPISAGEQVLNYYGPLSNSELLRRYGYVTSNHARYDVVELSWNMVLSVLQNHLRLDQTKWGQAINQLDEEETEDTFVIDRDLDEPDSRGDVHGEVKLKQLPADLEEQVATFLKAVRKVSPESIPDKRKRDEISVAVIHQALQLRLSEYPTSEAEDQALLQDPNFTDRQKMAIVVRLGEKKLLGEAIQVAAEKINTMTRNGDDASSEPSAKRHKSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V698</accession>
    <name>A0ABR1V698_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013477</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663483.1">
        <property type="nucleotide sequence ID" value="XM_066817791.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050851"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="16"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="492" mass="54913" checksum="EE932E75E1B7758A" modified="2025-10-08" version="1">MKPYFGLRGKQLNYAIGIIAGCDFLLFGYDQGVMGGILTMRNFLDDFPDIDPDGTPDKALQATRSETQGIAVAAYNLGCFLGAVITIWIGNPLGRRRMIILGTAIMVIGAILQASATTLPHFIVGRVITGIGNGGNTSTVPTWQSGDLAIAQARQARHDRGRAHHLWYYDQLLDRSWLQFRPGQRGLAFPAGVPDRLLNLPESPRWLVLREKEDEALDVLAALADTSIDDKEVRNEFIAIKDTVLEMKKGRFSDLFTQGKDRNFHRTLLGYTNQMFRPNTDASTIEQISGINLITYYAPVIYASLGMSSFMARLLAAINGTEYFIASWPAVYLVERVGRRKLMLFGAAGQAASMAILAGANSQEDSAPLPDRRCRLPLRFQHLLRHRMARHDLAVPPPRSSLCESEPLPTPCPLQVTNWIFNFMVVMITPVAFNTIGYQTYIIFAVINAFMVPSVYFFYPETAYRSLEEMDAIFPQGGRRRGLLPGRQRRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7J3</accession>
    <name>A0ABR1V7J3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013911</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663917.1">
        <property type="nucleotide sequence ID" value="XM_066818225.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051285"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="169" mass="19398" checksum="4550A4DF9DC75579" modified="2025-10-08" version="1">MSAQDRVQQYVSQLDRELSKYPALNNLEKQTSVPKVYAVIGFATLYFFFIIFNLGGQLLTNLAGFIIPGYYSMQALFTVSKTDDTQWLTYWVVFSFFTVLESLLSVVYWFPFYYTFKFIFLLWLALPTFGGANLIFRSFLQPMFGRYFSESGSTAANLRAKADSLGKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8X7</accession>
    <name>A0ABR1V8X7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-3' exoribonuclease 1</fullName>
            <ecNumber evidence="5">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_013503</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the 5'-3' exonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663509.1">
        <property type="nucleotide sequence ID" value="XM_066817817.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050877"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016494">
        <property type="entry name" value="5_3_exoribonuclease_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041385">
        <property type="entry name" value="SH3_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040992">
        <property type="entry name" value="XRN1_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047007">
        <property type="entry name" value="XRN1_D1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041106">
        <property type="entry name" value="XRN1_D2_D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047008">
        <property type="entry name" value="XRN1_SH3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18129">
        <property type="entry name" value="SH3_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18332">
        <property type="entry name" value="XRN1_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18334">
        <property type="entry name" value="XRN1_D2_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006743">
        <property type="entry name" value="Exonuclease_Xnr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="1 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="8">
        <location>
            <begin position="553"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 D1" evidence="10">
        <location>
            <begin position="700"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease Xrn1 D2/D3" evidence="11">
        <location>
            <begin position="967"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 SH3-like" evidence="9">
        <location>
            <begin position="1166"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1256"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1266"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1329"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1369"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1416"/>
            <end position="1425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8066756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1435" mass="160559" checksum="FF61843C888A1E2E" modified="2025-10-08" version="1">MGVPKFFRWLSERYPAISQLIAENRIPEFDNLYLDMNGIIHNCTHKDSDDATFRLTEEEMFIRIFNYIEHLFGKIKPKKLFFMAIDGVAPRAKMNQQRARRFRTALDAEKARDKAIKEGVEMPKEAPFDSNCITPGTEFMAKLTRHLKYFINKKVTQDSDWQGCDIVLSGHEVPGEGEHKIMEYIRNAKAQPDYDHNVRHCLYGLDADLIMLGLLTHDPHFCLLREEVTFGRASKSASKELEHQNFYLMHLCIVREYLELEFQELKAEGATKFPFDMERVIDDFILMAFFVGNDFLPNLPHLHINEGALATMFRIYKEVLPQCDAYINEGGVINLQSLGLLLDQLSKEENRHFEHENSDQKWLRSKQLAEAKGEEMPKTKGKVIMTSAQKELWKKVKKYIQKPREDPLDLGTELAAADRQFIKDLAGDMRLEWRTAHDDEGRRHLVVSLPGKANGNADEEDDEEVEAGFALNRVMKKYDSAQVIDVSATESQDSMAIKYKEKFGEWKNEYYSSKFKEWTPESKETELRLLCENYVQGLQWVLYYYYRGGFNADVDFQLGQPFRPYEQLMGVLPDRSKSIVPAVYHPLMTDPKSPIIDFYPRDFELDMNGKKMEWEAIVKIPFIDEKRLLEAMATKNDLLSADEKARNDFGVSLKFTYDPTAQPIVYPSSMVGVFPDIPGCQCVENIYDLPTADGAKLYRGLLDGAKLNIEALAGFPSLATLPYTASLDYHGVNVFQQDSRNQSMIVTLSDVEMRSSIETAKLKLGQTCHVGYPFLQEAKIVSVTDRDYEYTHDAKGKIVQRHLDGSEMQTWQKKAAQLGNFYSKRLGIVIGPIEVTVQVDMLKGLIKTKEGALVKEYGYIPGTEKDHAAQVIVDEVVSEDQRFIEREALPIEEEFPLGSNVFFLGQTVQDFLYYGRPARVLGHKDGLVETVMVFHHPKDRQPQPKAKGQDFVPHESKYAARFSTVAKPVVAAGDSLGNYETAVNVAKNIGVSPLVLSKIASSLFVYTVGNMKVNLGLNLKFEGRKLKVLGYTRKGPRGWEYSSAAQALIAQYASKFPDLFAGMMQNPQGNELRETDLFRRMTPEEATLKVKEIGAWLKTVETSKFEKVPLDAEQLDSNVVKAIEKAVDGLIEEFNGGMGEDLFIKRKAPRDVLLRIEDAEQRLGDQKFSLGDRVIYAAGSGKVKTGSQGTVVGISTVGNHHMLDVVFDQPFMSGTALGERCTPFRGATVAAKTVLNTTSKHFLAIPKQANAGGHRIADSVQRTRGNSGGLRGRNGGTYRDAPAPPPLSGSFRGAMYGANHHASGRGRGAGNAVPHLQHSSLVYRPAPNGAHPQQLHQPAHQGGYQASNGYDWQSVGHGGQAHHAGQSHNYAQGQPSGQSNGAIYGAVPPPPNLNAKDNSRGRGRSRGRGRGEGRGQRGGRGGASRGRGAPQQNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9B5</accession>
    <name>A0ABR1V9B5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663644.1">
        <property type="nucleotide sequence ID" value="XM_066817952.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051012"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="135" mass="14218" checksum="6AC0E6BFB6F0D234" modified="2025-10-08" version="1">MVAQVKRSLIVTLPVSGKRLRQLGNDNDDDPPNPPPKRRRESTKRRVADSSDEDGDSGGSDKVGGRSASQSGHAVHNNNIGSDGDVHANADGERDVSLAAGIAVRDFATCDEATAQNDDGHQGSTRDDSARTSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VA69</accession>
    <name>A0ABR1VA69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Rho-GTPase-activating protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013877</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663883.1">
        <property type="nucleotide sequence ID" value="XM_066818191.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051251"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04436">
        <property type="entry name" value="DEP_fRgd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04399">
        <property type="entry name" value="RhoGAP_fRGD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF17">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN RGD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-BAR" evidence="6">
        <location>
            <begin position="2"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="DEP" evidence="4">
        <location>
            <begin position="212"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="5">
        <location>
            <begin position="465"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="670"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="775"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="343"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="670"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="692"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="798"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="851" mass="95310" checksum="95FD7351390A970F" modified="2025-10-08" version="1">MPSFADSFWTPDYAAGLGVLFSKLQQGVEEDRQVLTIARMRAEAEEAYGQRLGDIAPAADKIAGGFSKDDGASVRKAYDGVRTEMEDAAKNHKKIAQSIRDLVVNPFSRWCDAHESRLQDSQDELQARLKAHDRQVEVVKKLRSNYFNKCRLVEDLEEENKMAFQDAENSPKQNIPEIKVQKDEEKEDEDEIFEIGDETYQKEQVKKIIEHMLNTIKMGETKVPILGTYQNTSAGSDIVEYLQRHMDCSSVSYAERIGQDLISNGFLRLVGNVGSTFANSSRLFYQWRPKSFQISGVPEKKVAVSRTFSLPTSQDSTDSPIGAVSEYLQGWNVLGNSHPNETPADKLRREARETDDKYKAGVQKLDEMRCDLEESIFVHLKFLERCELDRLKAIKTVVLDFSGTIGNVIPSLQSTVDRMVLYQETVQPMGDLRYLLENYRTGSFAPKVVTYENYYNRVDEQTFGVDLEARARADKKRVPIIVTTLLTYLDHHYPDLEGDEARRGVWLIEVPLSQTHKLRNKINNGKPFTPEDIAEFDVPTVANVLKLYLLELPDSLISSHVYEIIRTIYTTPAADTADDARVGVLQQTLSQLRLTNIATLDACMNHFTRLIDLTSADDQYVQALAASLATCIIRPRTQSSLTMEEKHSHRLVRDLFAHKTAIFSELKRMSSLSHSGSVTAPNNRPRAISTDESNRRAHMEERQRALLEKVGTAGDRGRSRATSPAPSPRHRRDRSTGGPETRFPIQTSPTSSSDRHGRSSMASMASLNGTLKRDSLEVPDSAGSAPSTEPLGDAPSEEGSQGSPVDTKRSSLSSLGRNSVRFERGRRVTPVEPTVGEEKQGVTLVDAPMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAZ5</accession>
    <name>A0ABR1VAZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013951</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663957.1">
        <property type="nucleotide sequence ID" value="XM_066818265.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051325"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044970774" description="Peptidyl-prolyl cis-trans isomerase" evidence="4">
        <location>
            <begin position="29"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="39"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="269" mass="29272" checksum="8BDB49F8F8CDB2A2" modified="2025-10-08" version="1">MFNLRRLAVSALLLVGVSMVFFASTAEAAKGPKITHKVYFDITHGDEPVGRIVMGLYGKTVPKTADNFRALATGEKGFGYEGSTFHRVIKQFMIQGGDFTKGDGTGGKSIYGEKFPDENFKLKHTKPGMLSMANAGKDTNGSQFFITTVITSWLDGRHVVFGEVLEGMDIVTKIENVQTGAGDKPAKTVKIAKSGELEVPPEEETYGNSEWAGGYSNEVEANPLAEDTPSYGLSTFQKGAFFAVFVAVFVIYMRVTRPKTDLGYEKTMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VB66</accession>
    <name>A0ABR1VB66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein eS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS1</name>
        <name evidence="6" type="ORF">PG997_013920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eukaryotic ribosomal protein eS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663926.1">
        <property type="nucleotide sequence ID" value="XM_066818234.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051294"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03122">
        <property type="entry name" value="Ribosomal_eS1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001593">
        <property type="entry name" value="Ribosomal_eS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027500">
        <property type="entry name" value="Ribosomal_eS1_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11830">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01015">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01397">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0007">Acetylation</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="initiator methionine" description="Removed" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="modified residue" description="N-acetylalanine; partial" evidence="4">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8067173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="236" mass="26873" checksum="15D0214FED1D6AB0" modified="2025-10-08" version="1">MAVGKNKRLSKGKKGLKKKTVDPFSRKDWFGLKAPAPFNIRDVGKTLVNRTTGLKNANDALKGRILRVDEVQGKNCLTNFHGLDFTSDKLRSLVRKWQSLIEANVTVKTTDDYLLRLFAIAFTKRRPNQIKKTTYAASSQIRAIRKKMIEIIQREAASCTLQQLVSKLIPEVIGREIEKSTQGIYPLQNVHIRKVKLLKQPKFDLGALMTLHGESTTNEDGQKVEREFKERVLEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHA0</accession>
    <name>A0ABR1VHA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7907 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664412.1">
        <property type="nucleotide sequence ID" value="XM_066815122.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048182"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057229">
        <property type="entry name" value="DUF7907"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25484">
        <property type="entry name" value="DUF7907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045830496" description="DUF7907 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7907" evidence="2">
        <location>
            <begin position="28"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="211" mass="22883" checksum="B20A1A5C6383B411" modified="2025-10-08" version="1">MKFSLSASLLALAASAVQAQQPQNQTGPFFLHITGKEDKTIDGYAGACHAGAAIEGLCFANGPKPSGDNVNYASFYFNYTGNQDVDGAEVGFVSWNLQLAPGSDPAVVPSPMSFTYSITSNVAQPMFGPGNSQQSVGFDKDGKMFVFGSMDDATFEPDNRPHNPYQPKAYYNWFVCWQYVGSYYYHAVGWATTLPPHNPTCQAVDITQVMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHB0</accession>
    <name>A0ABR1VHB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664415.1">
        <property type="nucleotide sequence ID" value="XM_066815125.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048185"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="102" mass="11806" checksum="58B18AC279D215E3" modified="2025-10-08" version="1">MSSSQHALSMIRKTRLKFREYWSLVKAQPDGPPETYHCTYLVKWLNRSLSGFDGIVEGWKALFNLARPALLISFFGYESWNEHGKPGLNTESTRARNLKEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIR0</accession>
    <name>A0ABR1VIR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavine sensitivity control protein acr-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664830.1">
        <property type="nucleotide sequence ID" value="XM_066815540.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048600"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF51">
        <property type="entry name" value="ACRIFLAVINE SENSITIVITY CONTROL PROTEIN ACR-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8071022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="541" mass="59155" checksum="0393C9E7FA22C5A8" modified="2025-10-08" version="1">MAALPPCHNCRRNRKRCDRSVPSCNKCSSTGQDCLGYGKLLRWTGGAASRGRLAGSKPYALSGEAKQNTIVPFQPQRNSKPQSDNIITFGIAPTLRDPFSKIWMIQQGSICATLAWNPFRELIPISSSYSFLRHIIVAASALHYYNAGCHSSPTKAQPLVAKGALVDALRARQKAIKGLQEVLERHRLAPNDESLAHERDAVLATVLFFVNFALIDSGKGEWRAHMRAAGSLIAAHVTDSVTQPPLATSIPHLLGAESSTTSDDQNSFSLVALNAALKPGRVHGIPGSASIRDYIASDSVAYYIWGCTLDSLITPFPGRDTGSAQLEIDPVSILPILQRTEANSYHSCPTDLLVNILSTARLARSIGIENGGNPTSSQLKEGLLLLKDAQAFDIEAWAVRMCAASVELGFVNEDEIDYRTHAAATYRAAACLYVLLATPGLHSHIQEASSDPDLVDDLPFLPTTEDLVSTIFCQLSFIQVDSPLYKFTTWPVFMTGVETTSSERRAWVLSRLQGMWDLCPWGMIKSAMETLTNIWQLRIWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJG2</accession>
    <name>A0ABR1VJG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011589</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665194.1">
        <property type="nucleotide sequence ID" value="XM_066815904.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048964"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8071386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="349" mass="39502" checksum="28DD16532AAF8528" modified="2025-10-08" version="1">MLLQIPTNFAQEIVRLSQQHGAIYSLRMVRQRYIVIADAGIAQQLLVTQAAKTSCREGSYIASKALWSGMGVITSSYGDLWRKHRQILEQGLRSQTAESAAEAMRQPLARLHARLAAHAWDEPELQAVFAEYTLEVFLSMLLGPHHDRIPRSLFNQAIDAMNEMLSYRRARRWRSNLEDLIGSILEYIEPEQGSTPVVPFGHLLLQMEEAGKINTFEKCTLSMVWLTAANASFPGFYASFMKAISSVPRVQQKVRQELDSGRDAHFLPPARGERLPYCRAVLLEAMRCNHATIDSPHVVTEEITLGQWTIPAGTALLLDTWTINHDETRFPRPLEFEVSEKPPSMYITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJJ5</accession>
    <name>A0ABR1VJJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidine-specific methyltransferase SAM-dependent domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011588</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665193.1">
        <property type="nucleotide sequence ID" value="XM_066815903.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048963"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051128">
        <property type="entry name" value="EgtD_Methyltrsf_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397:SF2">
        <property type="entry name" value="HISTIDINE-SPECIFIC METHYLTRANSFERASE SAM-DEPENDENT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="5">
        <location>
            <begin position="19"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8071385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="342" mass="37633" checksum="E7D4BA184875B817" modified="2025-10-08" version="1">MTPYLSIHTIAPNQERLLRSLVVDGLNAEPKILPSVLLWDDAGHELFRKITKSQFYCGPQADSEIMKGRLREIREYLGDDGVLVELGAGSIPHTTAILEELYRHGAKTRYLAHDFCQNRLRQSLGRVGKELGTKYPESLHRMRGVAGTYEQVFEWLAKTNHLEGHRVLVIWLGNSLSHISDAEFPDMIEMLMRSIWQSRAASSMLIISVGGGGGQEASALLRSSYDAPDGSSAAFVANALRHANRLLGGANDLTLDPGIWKAVFRANAQGTAGVWAFRSQAPTQLVVDGRVVACAAGEEIDLITITPRDAANVTGLLALSATQVVVTWKHRSFDWSKYTLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJL1</accession>
    <name>A0ABR1VJL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665208.1">
        <property type="nucleotide sequence ID" value="XM_066815918.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048978"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="208" mass="23255" checksum="09C82718F9D777AB" modified="2025-10-08" version="1">MEPSEDIPRITACSSHRFLKIFSPRELSDEDRVFFDEKGTLSNSFLERLGETIANLDISQLSTDTEHMSGSWPGKTTMDLTDPGEPSKDKVELQLPDTPDPAQAPDDPRQTGHDEKKSGTPGPLEQTVESDRSSAFKIDVDEARKSLLQRMRRLQPDDDSLVRGEGFVLETAWSLVQAIVYGDEARCPSLVELVREYGESEEDRVQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VM11</accession>
    <name>A0ABR1VM11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665063.1">
        <property type="nucleotide sequence ID" value="XM_066815773.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048833"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="221" mass="23851" checksum="D3B23D428A2B1A75" modified="2025-10-08" version="1">MTPPFSSRSSLQDAFQWQTRSCEYSGAIVSRKSDPGKSAAGSEQGPGQMERLGTGTSETGGPDAWVGFLSNFVVTLEGEKEITREANVREENRGTTPNPKMQFQTLALTTLLAALAAAAPQAQEDAAAGGASQQQQQLLSKLPSCALPLPAGGLDQGQLRRRRLRLHLHQDGRLHPGRPAVRLQGLQARGPSVYVLSSSFSLFLVLVPVHVSLRISRRQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU92</accession>
    <name>A0ABR1VU92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665761.1">
        <property type="nucleotide sequence ID" value="XM_066813799.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046859"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="71" mass="8039" checksum="03AB529F554697B7" modified="2025-10-08" version="1">MAQYKASSRGQRDVDLLEEEADFFNGDVDSEDNTDNVDSLQESSEEEEEAVESTDEAEAAPHSKKRERMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVT1</accession>
    <name>A0ABR1VVT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase/reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010017</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666294.1">
        <property type="nucleotide sequence ID" value="XM_066814332.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047392"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF252">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="339" mass="36519" checksum="03146EFF9B6F7088" modified="2025-10-08" version="1">MTTPTVTFDLTPEQEASKLQFVRRQFSGAPPAVTRADVDLEGQTALVTGANGGIGLECCRQLLGLGVGNLVLAVRDEHKGEIARETLMADKCRASQNVEVWRLDYASYESVVAFARRAETVQPPLGIAVLNAAVNRASFALNPETGHEEDMQTNYLSTALLTLLLLRTFKTTSDASPSQGTGHIVLVSSDTAAWANFAEKTQDPLLPAFDEASRFRTFDRYATTKLLGQLFVAELARRVPASAAAVISCANPGLCHGSGLNRELGLPAAIFMRLLGRSAAVGARSLVRAATMQGERGHGQYIEDCVIRPMAPFVYSEEAKVVSQRLWKETMAELSFAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW31</accession>
    <name>A0ABR1VW31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010111</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666388.1">
        <property type="nucleotide sequence ID" value="XM_066814426.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047486"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF20">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE 1 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="10378" checksum="14DB33C4809E831F" modified="2025-10-08" version="1">MSTTTLYWLVGDDITYADLAWATWNDWLDGVLSCDADKKLEGYPHVRAWHERMTSRPAWKAAIETRVRLMNEQRLDSKWHAEGDGVVLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW58</accession>
    <name>A0ABR1VW58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666421.1">
        <property type="nucleotide sequence ID" value="XM_066814459.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047519"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="89" mass="9872" checksum="9FE54F3E0919146E" modified="2025-10-08" version="1">MSAAFPRVARQVASKRLFSTQMPLRQGHSSLGQELQGIFRPSMGVKSQKADWGKMVAKRAQTLGIYATGMTCILGWPWACQWALDGHIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWP9</accession>
    <name>A0ABR1VWP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Clavaminate synthase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665676.1">
        <property type="nucleotide sequence ID" value="XM_066813714.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046774"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420:SF1">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="40034" checksum="2DE34C774BA6F2B4" modified="2025-10-08" version="1">MATAQPVVVSLKDLKNGDISFETLQEAFGPESLGILVVKDVPQEFAGLRHQLLSYASYMGNLSESDFEKFTNEAAKYLVGWSLGREQLKNGGADDLKGSFYANCAFYVDPNREAATPTERFTLKDFPEYLAPNSWPPNETLPGFRPTMEQMCRLIIDTAVLVARACDRFAEKEIPEYPKSYLENVVQSSSTTKARLLHYYPMTEEIMKRGDEEDNWCSVHKDHGCLTGLTSAMFIDELKVNAKVPDLGGDVPDRLPTLDELAQSPDPQAGLWIKNRKGEPVQVKIPRDCIAFQTGEALERITRGKFKAVEHSVRGAYSKGVARNTLAVFTQPNLEDEVDLDQHISFGDFARGIIAKNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX52</accession>
    <name>A0ABR1VX52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010514</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666791.1">
        <property type="nucleotide sequence ID" value="XM_066814829.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047889"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="84" mass="9495" checksum="CB9825449103AA94" modified="2025-10-08" version="1">MCYHPEVLWACGCRETANNNLERCGGAMAYGINCIGTMPAPAHRTLHMAIPCPDCRSRLKRAALEQQGRDERNPRMLRRMTACF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXE4</accession>
    <name>A0ABR1VXE4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666457.1">
        <property type="nucleotide sequence ID" value="XM_066814495.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047555"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="27278" checksum="F170678B1DA5B5B7" modified="2025-10-08" version="1">MPTATEYFGYTALNYGPLTTTFTADPSCATATEGRVIYRSDDLRYQIAYAGDCATTTASPYYLGCFPSASKDMSLFASDVPVGVGLASYFSPGVACPSGWTTAGTMARATGAAGKPDAWNGTGSLAGDIWETVYDDTLGREVPLLEVYRQIMAPDETLAFCCPSSTVTTRFVSIVTEPEPSKTVESLRSTPLASVYEASEIAEMVVMTVVAAVPLIHKASDVPKNAAAGSLAPAAGGALAMAVPLATVVLGLFAGARMIVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYU6</accession>
    <name>A0ABR1VYU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009757</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the gemin-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666034.1">
        <property type="nucleotide sequence ID" value="XM_066814072.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047132"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035426">
        <property type="entry name" value="Gemin2/Brr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794:SF0">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794">
        <property type="entry name" value="GEMIN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04938">
        <property type="entry name" value="SIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="454"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="416"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="430"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="550" mass="60813" checksum="F4EA7875D978D717" modified="2025-10-08" version="1">MSSKRQAEDDSSRSTSKRQRQSTNKHSSQVDQTYGQRTAFGDLRDPTIPNDDELEWEDETDALAYLMSVRTEAHGIPNLLVASKPIGPSNDSVDRSIYADGKGDFRGFYQDGAYTALPEDYYDEEEYDENEELGETAADSPGGEDADYDEEYSDDASLGRPRNSNIAEIHEAYYGSLIQQYLNLRKILHSTPPASLVASLPFDNPTEVDNFGASPDTFRQWAGRVMNTDPLPAQIASMHKDGVIRLLRIILTGKFFRKGQELHERTSRWLWALLARLPDKGELYYQEIGWVRELGKRAVLFMVSLAEAEILHQDYDVRGTKDSDEGDGLDLEVDENLDDVSSEPASIDDIAPDQEDNPPNDQVKQDGAGTGNQDSQNQANDETVKPPVSPVPFKEESTPQPPEGAVDDATSPSDVEMPDDSDMDEGEVSAVSQPKIESTTADVEMAKSKLLAQLGGLDGAADDGEAAEPEPQEELLEPGEHEAQEETSEPAESLDDPDEAEDEEVARTKANVRATLNMILTVAGEFYGQRDLLEFRDPFGRISEEGNIHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VYW5</accession>
    <name>A0ABR1VYW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">methylcrotonoyl-CoA carboxylase</fullName>
            <ecNumber evidence="3">6.4.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-methylcrotonyl-CoA carboxylase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009711</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13589"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57344"/>
            <dbReference type="ChEBI" id="CHEBI:57346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AccD/PCCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665988.1">
        <property type="nucleotide sequence ID" value="XM_066814026.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047086"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045190">
        <property type="entry name" value="MCCB/AccD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855">
        <property type="entry name" value="ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855:SF13">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="7">
        <location>
            <begin position="76"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="8">
        <location>
            <begin position="336"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00026116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00052347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="578" mass="62387" checksum="4A9A44DB3955741C" modified="2025-10-08" version="1">MPLSRSPRDILSAGRQLTRSYRHVVPRHSLPLSRRTPPSCRAVSSYTAPYQANAISVIQSNVDSTSDEFRENKRAMGEAMARLERLTRAAQQGGSAKAKEKHLARKKLLPRDRVTALIDPGSTFMELSPLAGHQLYPEAEVPAGGIITGVGVVEGVTCMIVANDSTVKGGTYYPITVKKHLRAQAVAQENNLPCIYLVDSGGANLPHQSDVFPDRDHFGRIFYNQARMSAQGIPQISVVMGLCTAGGAYVPAMSDENIIVEKQGHIFLAGPPLVKAATGEEVSAEELGGGEMHTTVSGVSDYLAVDDAHAIILARRSISNLNWPSKAAPPAASFSEPLYPEAELLGIASTNLRKPLPIHEVIARLVDGSHFSEFKREYGSTLVTGFASIYGHRVGIVANNGILFATSAQKGAHFIELCAQRGIPLVFLQNISGFMVGKEAERDGIAKHGAKLVTAVSCADVPKFTVVVGGSYGAGNYGMCGRAYSPRFLWMWPSARIGVMGGEQLSKVMETVGQKPDPELRDRIESESDSVYSSARLWDDGVIPPQHTRRYLGLGLRAALSGKNEVKHGQTRFGVFRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7F8</accession>
    <name>A0ABR1W7F8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_007238</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="11">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666895.1">
        <property type="nucleotide sequence ID" value="XM_066811553.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044613"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF15">
        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 11" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0720">Serine protease</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045832879" description="tripeptidyl-peptidase II" evidence="12">
        <location>
            <begin position="19"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="13">
        <location>
            <begin position="210"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="11">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="547"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="548"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="571"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="573"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8079420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="591" mass="64510" checksum="79451DD22899DB65" modified="2025-10-08" version="1">MLAPTLVSLFLATGLVAGLPQPAAELVEHERAALVPNSWHLVRSATADDILTLRIAVKEHRKVDENHILARSDPNSPLYGKYLGADELNALLADSTSTDARQASWDKVERWIHQQNIPITRESSRGFEIQVPASQAESLFGAKFSYYTRDGDNKPVARTEAYSLPLGLRDDIDFVYPTIHFFDSARSRVAESKVERRQHFPTGPFDCSKYVCPVNLTEKYHIDYVPETASASKLSVAGFLEQYADHEDWKSFLAQFGLPKFGLGNEATQATYNVVNVNGAENKDSADQAQIEAQLDMEFSTAFTGPLNVTYHLPGNKPRPIEQNNQEPYLEYLDYLLALPEADMPQVVSISYTDDEQSVPLSYANQVCDRFSYLALRGVSVLVASGDAGTQGTTFSDCKGPDGENRFIPTFPASCPWVTTVGAATNWDGAAGYTAGGFSNYFTQPAWQKDAVAKYLASGETGIPENPYFAYNASGRGYPDVTLLGSDYLVLNQGRLTPSKGTSASTPVVAAMITLLNDIRLKKGMPVLGFLNPLLYAADVAEAGFQDITQSNINGCSTRDHQQAGFKATTGWDAASGLGAPDFAKLRKLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7J8</accession>
    <name>A0ABR1W7J8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666932.1">
        <property type="nucleotide sequence ID" value="XM_066811590.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044650"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045482856" evidence="1">
        <location>
            <begin position="18"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="9047" checksum="F0C15A8050C2B3F3" modified="2025-10-08" version="1">MQFTLVAALALPLLVAASPAPEPEQNAAQATSSTYYLDCGSNSVTNMCSAENSGASCNPTTGALTINLAGSCGACKCIKDPVCTRGCAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8G7</accession>
    <name>A0ABR1W8G7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667247.1">
        <property type="nucleotide sequence ID" value="XM_066811905.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044965"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046302035" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="18674" checksum="E71EA402577F9719" modified="2025-10-08" version="1">MYTSMLLLLLPVAVSGAAVVYSGDGCPSSAPAVDKSGDGFDDVSFRLNAFAVSSADVYSSTANCEVHVQASGASAGWQVGVSDVYVRGRLVLDPGAQMDFYVTVRGSLKNTGSSRTDQIATAHGSIPGDRVAWGPCTGSAGDIGILNVNFRTALQGGGYGSFGGKGADSAVESWDYVWRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W951</accession>
    <name>A0ABR1W951_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667471.1">
        <property type="nucleotide sequence ID" value="XM_066812129.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045189"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="207" mass="23537" checksum="72AAD7567CE97B0F" modified="2025-10-08" version="1">MATFEATRDFRAAAQDPKRAKERYSKWSRGSRPLPGSKDNILDPFRTDAKVRPQRSFPEAPRNRIRNHNIVKAKIPWDMPHNHSRAKVNPMEELNDPSSLTRSLIDTLPSSDRVEKKTSMADQALYSFDRVDSPGKPLSLDVFVKSDAKGTEKLVEREYEVLDINGDALKGRKARRILRHPSPKQHATSTDFDAEDVDGFQLIKAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9I4</accession>
    <name>A0ABR1W9I4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667629.1">
        <property type="nucleotide sequence ID" value="XM_066812287.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045347"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046933526" evidence="1">
        <location>
            <begin position="21"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="99" mass="10575" checksum="917F40009D773796" modified="2025-10-08" version="1">MVRLATLTLALAAAITGTSAKCTKACVPGQVYCGWALLQEYGCSETDLRNTKGGQYWDSTYTCAADAHSADEIEWCVGGSGHCQPPNNDHCDGINYCCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9K1</accession>
    <name>A0ABR1W9K1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007989</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667646.1">
        <property type="nucleotide sequence ID" value="XM_066812304.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045364"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF8">
        <property type="entry name" value="MFS GENERAL SUBSTRATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="513" mass="55573" checksum="DA0C963BC046525A" modified="2025-10-08" version="1">MEDDTDSFLGPERAVSQERDDNQKARRGPVPRRAVISALLILLFLVNFAQSLSSLPLNRVIERRLCREYYTEYDKSRIGHDGTVPEELCKVNEVQRGLAGIQGAVDTAWIVGDFVMTIPLGFMAEKYGQRAILWLNLIPRIWMLVWAVVVGYFEHALPTHAIIAAPVLSVLGGDCVFNSITYTIASGITDDYVLRATYFGWMGSISYVVSLGGPALAAASMTVLIWLPFWIGIALLLLAVPAVSLLPDHLGKAEANRSNTATALEQAEPLIPSPAPAVPMSQDSIVRAILRRLGTLRSISASHPRNLTLMFICFFLSSLASSDTKLLPQYISKRYHWSFASAGYLLSGKAVVNFVLLTVIIPWLLRSRHSPAGASAGNSDTDKANARYALICWVVSVIGASAIAVSTEIWLLFPSLLIYALGSALPIFTLSLLKSPAIAPKHEGDLAGSVDPETHIFSMVVMVKTLGSLLGAPLMAILWVYGINTGGAALGTPFFISAACYVLAIVVFRSVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9U9</accession>
    <name>A0ABR1W9U9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alternative oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008081</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667738.1">
        <property type="nucleotide sequence ID" value="XM_066812396.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045456"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="462" mass="52494" checksum="0752DB67E5854509" modified="2025-10-08" version="1">MHVAHRLLPQQLVASMSRRNLLLPACAILLLIAVWSWRLQPSPFEWSATSGYGHAPAAGVLHPPAPNTVDLSDPEAPFVGWPLRRICDEATYVEGLVFICDNNSGGIGNIRNYIQTCLRYAVEAGATSLVMPKIRQRSAEDLENLFTDYLPLSYMFDEDHFKNAWKTYCPQIMLYGNVTDIPHYMKGPDGQPAIQEISPKDFGNRGGCDWKDQNRHTDRFGQTFRGWLKNETFGIPPTKETPRLIRFKWGVLWDWQVYKDGPEFAATFGHILKFNKQLLRLGKVVLKNMHGFARSQGARSGEFLGAHLRTESDAMSFWPVYDTQAPAYLNKAIERGFKAAYLATGNSTEAKKFAGEAAEKAGVRVVTKRELLTDRDLEELDSLTWDQQGLVDFIALLGSTYFVGPMPSSFSVYMTLKRHLKTGGIYYRPYRPGTDGDGYSYMVGRFDQYWEDWLFMFDGMWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAH2</accession>
    <name>A0ABR1WAH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667507.1">
        <property type="nucleotide sequence ID" value="XM_066812165.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045225"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="95" mass="8936" checksum="4A1E0AA2593A0C04" modified="2025-10-08" version="1">MTKTQAQLPLSLENHTAVEGSPAAEDSPAADHSTAVEGSPAAEDSPAADHSTAVEGSPAAEGSPAAAAAVAAAGVGSTVVVVVAAAVEVGPAVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAZ0</accession>
    <name>A0ABR1WAZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Kinesin light chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667687.1">
        <property type="nucleotide sequence ID" value="XM_066812345.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045405"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="74" mass="8078" checksum="A0A8B8ABDC5B82CE" modified="2025-10-08" version="1">MAPRVIAVVAPPTERQLGLYRLVPRTVVEGLGGIGKTQVAIKAAYRVREVYPECSVFLIAGGGYNHVRECLPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB66</accession>
    <name>A0ABR1WB66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Het-c heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666873.1">
        <property type="nucleotide sequence ID" value="XM_066811531.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044591"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010816">
        <property type="entry name" value="Het-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052577">
        <property type="entry name" value="VWA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905">
        <property type="entry name" value="NG37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905:SF11">
        <property type="entry name" value="TINC (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07217">
        <property type="entry name" value="Het-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046773212" evidence="2">
        <location>
            <begin position="29"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="761"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="815" mass="88930" checksum="C31999B630A8AECF" modified="2025-10-08" version="1">MADSRAHFWLASLFLAVVFLATPAAAFGAGNISSSSPIEGINWRHGDIEDALLGIMMARALNKKGKEFSKVMVARVYFGNWLRDYSQAVDLGTIKTVSYEAIRLVVAILGFMNFGFGSKEFEVTEERLGCYRPEEHIDNPKGYGGGDDPKRYWHGLRGPVDEERELAIDPETGMINYIANENEEGIATSAGLLRHLLGRCIELGREHAATGNDDALYEAMRLMGTGLHCLEDFFAHSNYIELALIEMGNRDIFPHVGRDVRVVLEDVDFLHSVAGEVSDKLAANEMQELQEHLENGKNEDTSLLRKLLAMIPSSLFGGESQSDKIDQIQQDTATAQMDGLEVKPHREPEEITIWVSNIFKQIVPIIEWHDRIMKIISDALPRIPILPKIVEQLEDQLNAFVTAQIAPFVVPVIQQIQNEMGAGSEGIIQSSKDQQHRVFNDDNASDPTHSMLSKDHFTNLLNEPAGKTAQEMVKWVVPQLMAAMDDESMSRDQGRHGAAEGRQIFFDCVEHWWNDIPYEGQEDYRQRLSREGVLNGENHKEGEWDSGHGHGCLGKLEQHQQHGGKKKKEEWDDKIATAAADAIVGSVSGAFNDFVPGNNNSGNGGGNSPGGLLGGVASFLGDFLGNNKNSSSEQQSSGGGGEWRSSSPGREEYGRQDSFERRETFERADGDDYHSRPQEPSYGGGHAASFFSDDRGGDDRGGDSYSGGGGYGSSEYSREISGGGYGGGGGGHAASFFSDDRPSYDQGGYGQQPPPPPQQYYGGGGDYGGGYLPQGGYGGYPPQGGGYGGYPPQGGGYGGGGDGYNQRGGYYERRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB69</accession>
    <name>A0ABR1WB69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008563</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668220.1">
        <property type="nucleotide sequence ID" value="XM_066812878.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045938"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="53"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="503" mass="56567" checksum="C57F523AB5CAFDC6" modified="2025-10-08" version="1">MSTTTPSAVDIGGGPLEQSPATTTGEDSQIQSPKYEIRGMHENEVEDVEMYRPGGFILLGQGRWATVWLCRDHERNRWCALKIVAASHSSEDSGELLINRLLGDNGVHSAAAHHIMLPDDHFWVSGPNGRHLVLVLPLLGPSLPKWLEFNEHRFELKKKLCRQMIKAVEFLQTQGVCHGDFMPDNVLMKIRNLDHLNKDEILKALGGEIFGSGRRIADRIRTLSGEDPGPNAPSYAVVPTRWPIEDEDKIILEDIAIVDFGEAFVPGHFKGSQLIPGAFAAPEVAFMSEPGLPSDTWSLATTIMDVLGSSPFRNDVVPFTSSLEEYLGPLPVKYRAEFEKLRNEELAARYEYEKMRWQDWVLMEMVKPDDNPKLKVFRLTDSQRSDPAHPAAYKSVAALGEARNKAMQGGGYSHAISAALGKEKQIFFEETDPRYDPKSMDRYKMPREEAELLADLALKIFRYEPSERITAAEIMEHDCLREQEGAEEGSAPVFPKDWVPWPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB92</accession>
    <name>A0ABR1WB92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SMODS and SLOG-associating 2TM effector domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008526</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668183.1">
        <property type="nucleotide sequence ID" value="XM_066812841.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045901"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041622">
        <property type="entry name" value="SLATT_fungi"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033635">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793">
        <property type="entry name" value="SLATT_FUNGAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793:SF1">
        <property type="entry name" value="SMODS AND SLOG-ASSOCIATING 2TM EFFECTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18142">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="SMODS and SLOG-associating 2TM effector" evidence="3">
        <location>
            <begin position="78"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="212" mass="23674" checksum="EE16EA7CFFF91C99" modified="2025-10-08" version="1">MDDNQKPDAPPPQDPNQPRPPSPAVTAHDELRLLSHDEWVLFCRGVGCFKDEESESLVRPKCWYWPAKGLPDGLYRDVIWILMVLQLGLSACLTALGSFSQQDGKPITVIAAICTCIAGILALMHNSGLPDRYRSDRNEFYQVEVYIKEIMDTRLAAADQNIMEVMAGCYDQFRAARQTVQNNIPASYTPTSLTTPPRLPGTMQKPKPGLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBU9</accession>
    <name>A0ABR1WBU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008790</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668447.1">
        <property type="nucleotide sequence ID" value="XM_066813105.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046165"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="619"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="685"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="811" mass="91357" checksum="187CC6100768253F" modified="2025-10-08" version="1">MRPSSIVASQPVTGPRIFGINASIEVLEAACVHISNNNYPLGRRYIRPIENWVAQVADPMLLQQFFSLKHPTVAAVWERIYEYSVWRNKNASKVLMEVALRIRRGNWLRTHSAVHLRGAIIRADEDTTDRIMELWRTFIGHTEPPKLSGSFEIGDTAILALSNDNLLASMKLMMRQAARHGTNHQDLDDALGRLIFESRGWDVDILQWILHVGVTTNPVVSSWIPPSAQLLPSNWVLFCGPSSFPWTDLQAFFQKLGHGRRPFCSILVKTFVPIWGCVVAAKSGQKSLQQFMRSLHDTTPQEKCVDPEVKLLPRIEWDMHVATKWKNEKGMCYLDLLSQAARKGNLDMLAFLLSYGIWELRHIVGALVAASHAWRPNYMNDYQPALEHEKRISTVALLLDVDLKGIWDEASARRVIPCQECILEHCQERIDHQISSSAEPCAVLYRLFPYDALRKAIRYGFSFDTIEYLVAMGEKVHSERDESGNTMLIDALLSNSRDRYQVVQFLLRRGADPRINGVDMTVLEATLKNIVKFVDPNYFAIRSIEPASGRLDKDEERKVSLGLVNELYDLGSPIDQDPLHQKPRSKPLLVLLIECGAELSLIRQVVTAGANINEKCEDNVTTPLASAIYEDQLEVAEWLLAQGADANLFSCRSIFDRACHMGASFVQLLIEKGADVELPCERHSYALAPLHSAISRGYMDVVVMLLAHGVQINFPRPLFINSPEQYYAVDYAAFYGKLDVLKLLVESGGTSIHPGVSGFDKAFYCGYICGHIGVLTFLEQHTGWSTSTVVSSLKVKGVSRTLGWEWNDRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WC53</accession>
    <name>A0ABR1WC53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008907</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668564.1">
        <property type="nucleotide sequence ID" value="XM_066813222.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046282"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF9">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="9"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8081089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="601" mass="66800" checksum="F461531AFAB1A691" modified="2025-10-08" version="1">MVGIPKSNRCSFCKARKTKCDEAWPTCGTCQRAKRPCSGPPRMKFVINGCHSTSGGYDSASSTSERSDASTPRDDHNQTSPPRILKQHQPKFRCRGRNINEDRGSLHRLRLPNMPPKPRDITPTPADQLAAELIWCLNAAPGTGHDLYLWGASLGLLPPLLGQSAALQHATKLLTTTWSNIQRGYPRRAWLDAQLYDACLISLQQTLEQVFEDPTSKLTTTATLAAQTLLQKVEVNEPHCFCNDASVTHQSNHAAGLSAVISMGGCDQGFSELGLHLVFESFFTVLMGDVRCVRDSVFAEPAWSSAMHKALDAATSLKPKLLSRFYRFWLEVAVWPTLVRQLRQLHEKPTESMLAAEVILRASALLEYLEDLDKAIFAKAIELGSIVEVENNTNRTGRDDEKFTPTSYEFANYNLANFFRAHAFFTIIALRILQCANTFLTPLSPYGGYTECGEEDQSCHSHSPKQQQQQQLQSKILDFSRRLWQVYPYMRRRRPLELGGTLHLVVAYEAGDARQKALTCAALREVESGHDGSFPPPDEDATIVAEAMALTGRSLATNQDNELIDWDAELQDLGSMDLSSELFLWDLQGLGTDLGVEPALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLK5</accession>
    <name>A0ABR1WLK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_005648</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668886.1">
        <property type="nucleotide sequence ID" value="XM_066809963.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043023"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052478">
        <property type="entry name" value="Metabolite_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31779">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31779:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="573" mass="63120" checksum="20B85F14795C18D9" modified="2025-10-08" version="1">MESPKRKRARLACQPCRERKRKCDGRDPPCSTCSQWGYECSYQVRQSSSSSLSHTPALGSSPRAPNVIAGPQPLHFDVVTPATIRSTDTATSAHDGLRRRVEANSGATTVRRLGLKMDPNRAPRLNLFGWNIGARQLSSSIPVTAPLLVTEITSLDHMKALAQVYFDKLDPCYGFIDKHQFFNRLHSRWTSEPEPSVYDSVLAGVAALGCLFSQRNCTVTELHLVQSARSTLDQHIFSASASLDLLTGWLLRTIHLRLTDSPHATWIASSTLMHLIESLGLHSDSDVNPVYASSFPPSAQCDPDLKRRIVGVSHHLNAWTSFDLGLSRVLFQKHDLPLPPAPKPGDYTAELIRLLPTSVSLDPSVAAEDTGLLSTLSNILNGSHTQSPSVMAQTNLVLCLVRRILSQNLDMSTLAEQVLDLLKKALGCARSMAQDCSPWHQVANVPFHIICVLLIMDTRSSLAILPDAIQTVGFVASIYDTETMREAKRTAYLLVLLHQQRRKDDLAVFSKALAENQPEPRMDLPSQISTNFNNSEDHAWLEALVADLPSLRDADLDEFLNTDMTGGPLFLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMH4</accession>
    <name>A0ABR1WMH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669231.1">
        <property type="nucleotide sequence ID" value="XM_066810308.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043368"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="120" mass="13472" checksum="8ACEB37D019A9DF5" modified="2025-10-08" version="1">MIISPDRHIGEQNPPGLSATFEFRYQVGQFLRKRADNEAPHQASFRDIITPIFVLFVFVILTSYGIYRLVHLARTSMSVTSSSSSDSSSVFEQELRKDPHVHPDEDEELAAAAYTPTDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMT6</accession>
    <name>A0ABR1WMT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669335.1">
        <property type="nucleotide sequence ID" value="XM_066810412.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043472"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="53309" checksum="67D627F0520126B0" modified="2025-10-08" version="1">MAIFVDLDEEDEPTSPENHLNHNGFHELPPAATTGPKQRVRAQDGDNANVNDNPIESSLPTTTSTSTSSQQPPPTMPTPTIPFRNGMTEALGCYPIAMAVASLLDLNALDNLSRTCRGVRQGLLQYRSSLVTHTLHCVNEDVVVDPEDTFRYRARAGNWFYMQEMGGDRYNGKSGSCARDMVAECRRCAKVVCRNCAIKPPAPIVLRDRHRRLCIPCTKAPLGTLAKPPLLPETPLDADLMKNAICTCQTEGVWLCHPCGRSIRGTDHDYQSIWRWRNQYGEVLGGLGTGIGDGDRGVICGRDWECVASKEREQETDCDAEDARERSHCNTPLPWIATVTASSTTVSSLPSSSSTAAAHRPPSSASTSSGSGGGSGGSGEGAGQQQQQQQAQYSSSPLGPGYVRHEIEGIGGVVKTKRLTMVKVGACVPEWEDEKNRGEILGREVKGIARSWCGWCWRVIPGKQDMERAAAAAARHGSSSSGAAAAPISGELPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNF7</accession>
    <name>A0ABR1WNF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669558.1">
        <property type="nucleotide sequence ID" value="XM_066810635.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043695"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF17">
        <property type="entry name" value="STEROID 5-ALPHA REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="34911" checksum="9D6E9DD293112250" modified="2025-10-08" version="1">MGLLQTFLHITNFRSPFLRTLAPSAAAAFAIQTAFAIPSIAAQSERFYDASGALTFLSVTLLSLYLPSLRAKSAGAAVKLPSLLSPFLKSAGAGAGSLNWRQFALSGAVAFWSIRLGSFLFDRVMKEGKDSRFDEIKKSPSKFAVAWMGQATWVTLCLMPVIAINAIPPAVFASMPAAKLTDAIGMALYIGGLAFEVIADRQKSQWMHEKRTKQHDEQFMTRGLWSKSQYPNYFGECTLWTGIATAAAGVLVTSPVQVGLGLPGGVGGEDPRTPSFVTGVPLSEKKYDKRYGDRKDYQDWKKNTPSSSLDCDHKAYGVVCIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WP07</accession>
    <name>A0ABR1WP07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">4-coumarate-CoA ligase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_006483</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669721.1">
        <property type="nucleotide sequence ID" value="XM_066810798.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043858"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="53"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="5">
        <location>
            <begin position="454"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="164"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8085212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="547" mass="59662" checksum="16CFBA4E0AAE4EDC" modified="2025-10-08" version="1">MASVVEKTAQGTIYKAHRTLTVPSVDILTLLFESEECYSPDTKVLHADADEPSNCLTKGQVLVQFKRVARVLRDQYGVGTQGPSRDVVFNVSGGHFMLPLIFYATSAAEGIFSSTSPSATPEELAYQLKETTPKVIICNDDSKANAIAAAKLVGFPRAISSATAGRSTSNCTKPPTTPRSPSRTRSLTGGASPIGTTGLPKAMKLSHQNLVAESSLVLEPIKEYNAKYRGPEYEYIGIAHLPVAHIAGVMGYLINCVYMRGTIFWMKKFDFAKFCEYSKKYKMTTGFSVPPIYLLITKLPNVTDQFDTWVDAITGAAPMGEELQVAVGKKLGKGTTRLRQTWGLSETTGSITVVPLETEHWRPGTVGSLVANHSARLVDDDGHDVELGKEGEILVKGPVVIKGYWNNPKADAEAFKDDWFYTGDIGVFRDGWLYILTLVQELIKYKGTQVAPAELEALLLTHPKIQDVAVIGVEGNGTELPRAYVVADPNKVSEEEIKAFVAKQVAPYKQLRGGVIYLPAIPKSPSGKILRKELRAMAKKESQTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPF4</accession>
    <name>A0ABR1WPF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669918.1">
        <property type="nucleotide sequence ID" value="XM_066810995.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044055"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="141" mass="15306" checksum="C84BC646F842A851" modified="2025-10-08" version="1">MQNHGRDAEYRPPLPPRSPRPPLAAAYPGDHRFTSFPPPPGPPPPRSQSSSPVFPEGPPPTLPPRRPAGFGGAAVYGQRPPDGRSASGSSLSPHWNSERPTLLSFPPPPPRLAGHIHLMEDHIRPMGANLLRYLPVLQPNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPK8</accession>
    <name>A0ABR1WPK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669852.1">
        <property type="nucleotide sequence ID" value="XM_066810929.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043989"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="384" mass="42027" checksum="30360748E072175C" modified="2025-10-08" version="1">MFFNAYNNGALAPGASHENLAEMKRHVQSLEKCANAYFRDIQRDMKCGPDYDLKCRFTDWNYVKLAMERITDDFSKRLEARARQPAPAPTNMWETVQPKYSKHDSDWQRSAPRTSRRSRNFFEEVEEVRPEALWYEPSNDFDSPAELFTERVPEISPLSRLTTTAPKNKPSIMEKTPKTSSTMKTSATSVKPKTVANPESKPGDWVPPHLRGPQKKTPTAPEKPAMPESVDKTVKPKQQIAWVPPHLRGAPATKKPVATSNVAAATGPVKPKEDKVPPHLLGSAKPSAAKVTPNQRRALVTPPPAAAASTASSGAASSANSPVSSSSESSSNVLIDISDSPATVFETSAGNRATHGTKDVWEALMQLTNEGLLMNTSTIGIQAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPP6</accession>
    <name>A0ABR1WPP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chromatin structure-remodeling complex subunit rsc7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006782</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670020.1">
        <property type="nucleotide sequence ID" value="XM_066811097.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044157"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013933">
        <property type="entry name" value="CRC_Rsc7/Swp82"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF3">
        <property type="entry name" value="CHROMATIN STRUCTURE-REMODELING COMPLEX SUBUNIT RSC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08624">
        <property type="entry name" value="CRC_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="57281" checksum="82F96EE572F1CF7C" modified="2025-10-08" version="1">MPGRRSGRAAARRAAEKMESTPKTFDEIEDEPMRDVEGDASDAEVQPEAEDHGDDSAAEPDEDNQDPESEAEASAKSPTPPPQPVIRRRRLGRPPKNRPPDWDTLPIEPPNRDPNDTPRRRGRGGWRGRGGRKGQSYQPTQQSIDKEGTMANIVDDEVVLPEDPEGETKVDKNGHLLGGREYRCRTFTVHGRGDRLYMLSTEPARCVGFRDSYLFFTKHRRLYKIIVDEEEKRDMIERDIIPHSYKGRAIGIVTARSVFREFGALIVVGGRRINDDYEVAARRAEGAVEGEIADPNDRFVPGEEYNKNQYVAWHGASAVYHSGVPSVPAQSGKPEFKKKRVTVTDSNWQLEHARAAAQFNAEIGAIRRHNNKGVYDIHTNTVQFPASMQPTRARILQVADSSAPTDSALFAPLDPKIPRNFKVVDTIMEIPPAGVSSAVYEQRETPPFLKDFQGLGSISDDIKDLLPPECRKAFDEAVGQEAEWKSHWGPENETTHRRPPIIDAAIVPFSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPY3</accession>
    <name>A0ABR1WPY3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670114.1">
        <property type="nucleotide sequence ID" value="XM_066811191.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044251"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="608" mass="67165" checksum="B30695DD041B727D" modified="2025-10-08" version="1">MDHFNSTVFNGTVVSTRRGFTVTKQKHKGLSFVNASIQDAETRTKPQTTTKTGNVLPPAATITFVTNQGEGKKGTAGQLKTTAANKGVRSSPKSDISKRRPKTRTRGRSCSSSTSASTHGSVASDLALSDTPDGRETGKGSNPLSKPLPPWASYKRPLSPPDFVRRLTFMAYALTPCKAYALDEFRLSGDGSLSVPEEIWLEKDPTSIHCATTLGVLYDTLASGKREAERLSSLSSQLVSVINRKLNAAEQTKTANNVTIHGVSALAIIAGYQGKYDHWQVHMKGLMRLLGIVGDQDRLDVRTINTIRKYVHTLPDPEADFTGAISSATKPCIPFARLHHELLVPPMVYDTAMIRAIQQHLQACALDPATVKTISDLALFNRYMEYLTMPGSSSKHDTQIVIEEYYFLKHQLLCKPRPLRESEEAISVDFSSSMPLDPNTDPYTNSIEAAVRILSLLLIRDPTLDLPCETVLTDILHQHTRTILECRRQQHQIVNTMVDPKMLLQEPWPVHPQTPTLVWICITGHYFSSLKAGATATSSSKQACFIYRELWIDLLGPGKAAHPELVSDGELELCRCLSMRHLRGETYSERGDVGNLARATKAEQYLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ46</accession>
    <name>A0ABR1WQ46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Seipin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_005876</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669114.1">
        <property type="nucleotide sequence ID" value="XM_066810191.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043251"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23995">
        <property type="entry name" value="Seipin_BSCL2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009617">
        <property type="entry name" value="Seipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212">
        <property type="entry name" value="BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212:SF0">
        <property type="entry name" value="SEIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06775">
        <property type="entry name" value="Seipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="289"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="349"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="349"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="461"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8084605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="52866" checksum="BE6F7C5BA17B6508" modified="2025-10-08" version="1">MSLVAKKAIELVKRPIRLATAPTAQRAYINTFLFISTSVALLCIASLAYPIFYYSYVPKKVVSLPIHLQYNVGPNPYGLASLSHDLMLDTAYDVSVHLTLPRSPPNLGHGNFMVALVATRSVLEDPAQSWGPAALTTPVDPYVDILAAPGENVVFSSRRAALLPYEDPFVSRASRALFLLWHVLVGSSSSSAGRITLDLPMGELVEFRDQLPLSLLLDVQAGQTLQVYAARVELVARLTGVRWLMYNHRIFSFVVCTALFWSAEMISMAAAWAVLMFFFSGNGGGDNSGVVGPRKPKGGNDGDDGDFRDPPPPGQPTPSKGFGGSGAVAIASGKLKVEHANGRERQLAIKQEEEHEDRNWAGRDADGATDVVRARREKRPESNDNSGDRRIKEESVERGRQRPLSSITTAVASSSSLGSPRQSKRQRGGAGGAAQETAAAANGNAYEDEGYDDEEYQDIGGSVGAGTGSSYGQGVDGLVRRRSSSSGKNPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ67</accession>
    <name>A0ABR1WQ67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670184.1">
        <property type="nucleotide sequence ID" value="XM_066811261.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044321"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470:SF1">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="225"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="455" mass="50861" checksum="BDB11D8F919BA744" modified="2025-10-08" version="1">MDHTYGDEFRTPSGKRPLATLQDTEDLEPTKKRPSYGERLALQVREWLDLIPDSSETCLDGRRETSNGGGGFQGPATPPFSQWTPSTSHISEARTCYSCRTGVTEKLLVEKVDYRYRHLAWNNIIYAPAGLGPTVPATVSAACDLLQRPRDETEPSREQVLKEDGVLRLLEFQEDGTMEYELETWFGDYVFPSGGALYRAGLTLQNRGPFEPDCVPGGAASDRVAVPQPDMLYGYDTMYHRISPFTRLKGHDCEGLHPSIANVAGPYVGYPFFLIEIAPDGQDGGGCLWIAINQCLGGAATCAKAINKLDRLLQERGGTGAPQVDDAIFSIAANQYTAELLVSYVESDKSGDDCYCTRRAASFLLSDPDHFLKFRRYVRNIVDWGKGHRLRQILAALDYLVELERKEDEAMASKEDGATTKEEDEAMTENEEATTRKEKETIADRYNLRPRRRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQN0</accession>
    <name>A0ABR1WQN0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007004</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670242.1">
        <property type="nucleotide sequence ID" value="XM_066811319.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044379"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045438126" description="Tyrosinase copper-binding domain-containing protein" evidence="4">
        <location>
            <begin position="16"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="6">
        <location>
            <begin position="245"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8085733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="319" mass="35402" checksum="0BCA9D6B57C91277" modified="2025-10-08" version="1">MQFFSFVLSAGLCAAATIPRQAAAADGNACANPAKRVEWRTMTAEVQKQYIDAVKCLKTKPSGMGLNTTRYDDFPYVHTHLDNTIHTVAMFLPWHRLFVQVYEDSLRDCGYKGPMAYWDWTLDTADVTKAPVWDVETGFGGNGDPAIDPMKESSSKKCLVDGPLKGFEVAYTMNGYAPHCLARNWNSGIAFPGDMLADSYTKEVVDEVSAQKTYVDFRYKLEGGPHGAIHSAVGGDMSPATSPNDPIFFLHHAQIDRLWTQWQMEKPETRTTEFGGPKTQDKEPGEASAEDVMPYLGLVPDVKVKEILATGTERLCYTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQN4</accession>
    <name>A0ABR1WQN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Formylmethionine deformylase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670371.1">
        <property type="nucleotide sequence ID" value="XM_066811448.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044508"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF3">
        <property type="entry name" value="FORMYLMETHIONINE DEFORMYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="748"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="891" mass="97318" checksum="5F108442C21B85BD" modified="2025-10-08" version="1">MAHVEDGNERHRQRMAGAPAASAGGSTVHATAGTQASPPHGYLYASDTNTYNNAYSNTRNQQYSYASPVSPALQWAPGGDIGAQFAGYNGQQQQHHHVSPELSSAGFGGVMGQQQQQASSTFNNGQIPRSGTRPKPSPLQFEDSNHDNMYASPGLSTGTTYAPLGTPFQYSRADSEARLLRSQQHKQTPSTGTAPPPYAAFLAPPKKWYQLRQAWIMYFFFSFGLLCAAGHHLFYKSLDGKPAVDQLTMLRYGTALAFAAKAGFLACIITAFRQRIWATVRNKILSVAAIDSLFAATEDVVALFNIEVYKKARIAMLLAVVAWLTPIVIILTSNTLVVKMANEVQNTTCPGIRTLNFSQEETEDWRNPTKIDRLIGTSLSTWNTTKNPNIPDDAEHWFDYYTKGSRQFSQVATLATFSQQVMSPNDAAVEICGNGWNCTYTINFTAPGYKCTELASDAGSKPRLGENTAPFGMEVLLPAGNNSYQVHATLGEYSSVQYARVAPGGIPIDANDTVIPTKDLPPHLGAFRTEPIIWLGYSMFACEHYVVDYEVDFKFDGKEQSTNVTKRNFLHPVLDTVYQPGAEANDGTGDNITALPVDRYIVPTNTGPYRLMAAYHSLGAHLRSFLNGTVTSNPVSNPIANSDVLQTKLLDPRSDLFPYPNLPDLVQSFYEDIILSLFSNQQFLAVVWAKKPDTKSGATTTGPKKGLDGIALDKEDKNKSANVDPATLYNCTKSRYENRFKYVDSQLWIVYACAILCALVAMALGTAAVLENEGVLRNTKFSSIVAATRGPALEKVPWREDNHGDITPDVKKMRVGYGVVHQSSPLSGGGVTGFGGSDGLGLSSNDYNPRRSAMVSPELVQQGFGEEVRYGFGLEGDVRQTRREGSLFRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRK7</accession>
    <name>A0ABR1WRK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669322.1">
        <property type="nucleotide sequence ID" value="XM_066810399.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043459"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055449">
        <property type="entry name" value="Iec3-like_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032742">
        <property type="entry name" value="Iec3_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24244">
        <property type="entry name" value="Iec3-like_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14612">
        <property type="entry name" value="Ino80_Iec3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INO80 complex subunit 3 N-terminal" evidence="2">
        <location>
            <begin position="32"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="INO80 complex subunit 3-like middle region" evidence="3">
        <location>
            <begin position="114"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="302" mass="34567" checksum="3B06840520EFDB17" modified="2025-10-08" version="1">MDDTSIKAEPGFRDRDRSLDDDDRADAKPSYKSWKKKYRKMRLQFDQRMQQSEELHQCEQKALQTAKRLAIENDRLMDMLISINESPQIPSRAPHRLEQTHQVPEAVDRRGPHNSFATTVEHYPEVLEDIEPKDPELYPTSFLKADDIDNYVAELDARIGLKAKPTIPPPASSIPSHSGAAANFALRNPTSVYNWLRRHAPKTFLQDLEKEKDKDKAKERERDHDHSEKVDGGSRLVRDPAESMDWEEEAGYDAPSMGSVRGKRKREDDAGYRPKGGASRPTKKRKSRDLGSSTPRVRKSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS02</accession>
    <name>A0ABR1WS02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670239.1">
        <property type="nucleotide sequence ID" value="XM_066811316.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044376"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007011">
        <property type="entry name" value="LEA_SMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04927">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP" evidence="2">
        <location>
            <begin position="17"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="76" mass="7345" checksum="5C7FB3C0E87BBDCC" modified="2025-10-08" version="1">MPSGKSGHGGCGGGKGSPMTPSDASRIQSGQARSGGDMSSGGFAARAQGAGARNENTGYQSYGHSRGQGGDGQGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX07</accession>
    <name>A0ABR1WX07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002636</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670569.1">
        <property type="nucleotide sequence ID" value="XM_066806951.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040011"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013586">
        <property type="entry name" value="PSMD3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057985">
        <property type="entry name" value="TPR_PSMD3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08375">
        <property type="entry name" value="Rpn3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25573">
        <property type="entry name" value="TPR_PSMD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="335"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="166"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="559"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="180"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="559"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="574"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8087675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="589" mass="65693" checksum="06815F974A54BE1A" modified="2025-10-08" version="1">MPGKTPNSNGRKPVENGLQKNSKDADKSAAKGKPAAKKGAKEGEDMTVVVPPSKSTKQSSQPPPADAEGDVAMEDSEKTEEELEVKVDPVTQTISDIKSNFALLDRAVALFDARFSLRALRSISSLRKRLNPDILAQVIAESYPPTSPSASVAKQLLSAIGRENVPLGRQPTGSEMEVDSEPKTQAKNGAKKDKETNKELIPEVDVFLAILVQVYMFDTKQFQQGANFSKYLSERIHSLNRRTLDSLSAKVYFYFSLFCEQLTPQAPSPQSPVVTLRPTLLAALRTAILRKDVDTQASVIVLLLRSYLLTSHISQADLLVSHTQFPENAANNQVARFLYYLGRIRAIQLRYTEAHEHLTAATRKAPASQCALGFSQTATKLLLVVELLMGDIPERATFRANNMEQALHPYFLLVQAVRVGNLEDFESTLAEHADTFRRDSTYSLILRLRQNVIKTGIRMMSLSYSRISLRDICIRLHLGSEETAEYIVAKAIRDGVIEATLDRERGFMKSKEVGDVYATREPGEAFHDRIRACLALHDESVKAMRFPMNQHRLELKNAQEAREREREMAKEIQEGDLDEDDLGGDFDGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX54</accession>
    <name>A0ABR1WX54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_002705</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670638.1">
        <property type="nucleotide sequence ID" value="XM_066807020.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040080"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="81"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8087744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="539" mass="57661" checksum="8CB3039535720AA5" modified="2025-10-08" version="1">MSKQYTFFTESIQSPNSTSSLGPEQGEISSVTLQTTDNTPKPDSMAPLDMTPSKGPGETAAVDEHLPLIPAIRRFSKVTGYCLAMSVAIIGWGYDLVVVGSIVSVDSFLRDYGDLYEGALIIPSTWLSLWLGLPPVGSITGSALGGWLQDRVGRRINLMLGSVVSAAAVAIIFFSHLPPRQIDCRAMLTVGLTVQGLSVGMIKTTAITYVSENAPTCLRGPAMALFPSVTLLGQLIGSIVVYVVSGVEGQTGYLGAFGSQWALSIAPFVLACGFEKRALKSAKALYVPKVDPQGTLESIRVVIEEERAMAAQASYRACFRGTNLRRTLIVILAHVMPTLFGLDLLSSASYFLKLLGLSSSTALLIMIGGVVAGIISNGLGIWVVSRFRWRRISLLSLSAALVLWTAFAISGFWPSETTAWLAVALMLSVILVCGVGVWPASYAIAGETSALLLRSPTQGLGGVMEHLLSAVMAIVLPYIYNSDAGNLGAKTAFVYTGLCAFALAATWLCVPELKGRSMMHIDHMFEMKLPTRQFGRWVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXD3</accession>
    <name>A0ABR1WXD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aromatic aminotransferase Aro8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_002778</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670711.1">
        <property type="nucleotide sequence ID" value="XM_066807093.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040153"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF21">
        <property type="entry name" value="AROMATIC_AMINOADIPATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8087817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="160" mass="18032" checksum="B51AB3598297D485" modified="2025-10-08" version="1">MRTLIPSLLSMDTDGRVLRHDSFSKVVVPGSRVGWVTGSEQVIERYIRHAECCSQGPSGFSQAIARADKNNYHHQQLWLKVDHTRHPHASDKSLLELEEEIFDSCIERGVLACRGSWFRAEHDRPLSGLFFRTTYAAASEEQMAVAIERFGDAVRGSFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXF6</accession>
    <name>A0ABR1WXF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670743.1">
        <property type="nucleotide sequence ID" value="XM_066807125.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040185"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF3">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="60"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="291" mass="31574" checksum="13820C53F5663D6C" modified="2025-10-08" version="1">MKNPFCLGAVYKTIDDGQELKADIRVPYPKEGKPFVIDIPSEAGLGVSYSIINKKHSEALIHERRYVVVSPEYRALDPAIAGSIKAPIQDCRDLLAWIYDGGLQRALDAEHPGNYPVDYDHVYASGISYGGLLALSLGWNVPRPVAGILDIAGPCHLSDDQWKASQEATSRLPSQQKHSDPNSLCLEAAPYSSIFDAATLPANDDHLRDVDPALNVRGLSFPPVFIVHGTGDEMVPIGLSRHLLAQLREQGVRCELAEVEGAGHLFASALRDSPEALEQVSRGVDFLTSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYU3</accession>
    <name>A0ABR1WYU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Exo-1,4-beta-D-glucosaminidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003238</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671171.1">
        <property type="nucleotide sequence ID" value="XM_066807553.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040613"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043534">
        <property type="entry name" value="EBDG/EBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041351">
        <property type="entry name" value="Ig_GlcNase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43536">
        <property type="entry name" value="MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43536:SF1">
        <property type="entry name" value="MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18368">
        <property type="entry name" value="Ig_GlcNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="6">
        <location>
            <begin position="23"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="4">
        <location>
            <begin position="194"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Exo-beta-D-glucosaminidase Ig-fold" evidence="5">
        <location>
            <begin position="738"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="851" mass="94882" checksum="681AF67A5C608656" modified="2025-10-08" version="1">MGHPHFAARWEAIAQLSLPGANVTDWHHINTSRCTLMGCLLHAGVYDDSKLFFSDNLKSFNRSQFAVPWLYRNEFKLNPKPGQHYFLQTNGITSKADILLNGHSVTTKDFQVGSYAGYEYEVTEMVNRGPNGLLIQVYPTDYNYDFALGFVDWNPYPPDNGTGVWRDVVVRQTGPVALEPLRVATDFELPVGKGVANVTLKATARNLENRNLTFAVQSTILAKSGGAPTVKTQSVTLGPYQSVDISLTTTLTRPSIWWPKAWGGQPLYSGKISVLMENSSVSDTVGQDFGIRKVTSSINAHNDTIFSINGHPFQVIGGGYSSDMFLRWDTAKFETQAQYMLDLGHNTRAKWNTQRLYEVADRLGLMVLPGWECCDKWEAWQYNNDLAVKSDWAAHDYGIANASMRHEAAMLQSHPSLLGFLVGSDYWPDDNATAIYMDAFKSTDWQNPIVASASKRSYPAALGPGGMKMDGPYDWVPPNYWYDAEPSEDRLGAAFGFGSELGAGVGTPELGSLKKFLTKEDLDDLWKKPEKGLYHMSTNVSSFYDRKIYNEALWKRMGAPTSLDDYLMKAQMMDYEATRAQFESVSAFWSKKRPATGLIYWMLNNAWPSLHWNLFDYYMRPAGSYFGAKVGARPEHVAFDYASRELYLINHSIDRRGPRTISVDIVGLRGEKLASTTVRARTEPNKSKSVHKLSPLKGATDVDFLRVVLTDEKRQTLSRNVYWIAKTIDRLDWDNSDWFYTPVTKYANYSALNQLEAAEVTTTVTPSKGGLNSSAGHDVLLENHSSVPAVFVSLNLVDGAGGDVVPVFWSDNYVTLLPHEKLTLRVTSRAKGAAAVQVRGKNVAPVTVALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X002</accession>
    <name>A0ABR1X002_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Catalase</fullName>
            <ecNumber evidence="10">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_003643</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="10"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671576.1">
        <property type="nucleotide sequence ID" value="XM_066807958.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041018"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08157">
        <property type="entry name" value="catalase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF9">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="12">
        <location>
            <begin position="20"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8088682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="509" mass="57536" checksum="7B661ECFDF663955" modified="2025-10-08" version="1">MATNSAPASTFKYNEQPVYTTSNGCPVENPSKWQRVGTQGPLLLQDFHLIDLLAHFDRERIPERVVHAKGAGAYGEFEVTDDISDICSIGMLTGIGKKTPCVARFSTVGGEKGSADSARDPRGASKKLIGHGAGFAIKFYTEDGNWDWVYNNTPVFFLRDPTNFPLFIHTQKRNPQTNLKDATMFWDYLSTHPESIHQVMHLFSDRGTPYSYRFMNGYSGHTHKFVKPDGSFVYVQIHLKTDQGSKTMTNEEAGKMASENPDFSTQDLFEAIQRGEHPSWTVYVQVLTPEQAEKFKWNIFDLTKVWPQGEVPLRRFGKMTLNRNVENYFAEIEQVAFSPSHLVPGVEPSADPVLQSRLFSYPDTHRHRLGVNYQQIPVNAPLKAFNPYQRDGAMSVNGNYGANPNYPSSYRPLTYKPISPTNPHEKWAGEAVTALFDDMQPHDYEQANGLWKVLGRTPDQQENYINNVAGHLCNAHVDTRRRTYQMFSRVNPELGSAIESATEKSVPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X085</accession>
    <name>A0ABR1X085_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003799</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671732.1">
        <property type="nucleotide sequence ID" value="XM_066808114.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041174"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF115">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="187" mass="21050" checksum="450A733357C079C1" modified="2025-10-08" version="1" fragment="single">TRLEPFKDTYTNMDHSHMDHGGMDHGDMGHGGGGGMSDMCNMNMLFTWDTTNLCIVFRQWHVRGPVSLIFSLLAVVLICAGYEFLRDLIRRYEASAARRAEELPTQEQVTESTPFLWSTGLRQVTVEKRSHVVKAALYAVQTFYAFMIMLLFMTYNGWIMVAVAVGAFLGYLVFGKSTSATKETACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0D0</accession>
    <name>A0ABR1X0D0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671775.1">
        <property type="nucleotide sequence ID" value="XM_066808157.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041217"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="27442" checksum="520EC4B87AD0458E" modified="2025-10-08" version="1">MGSTSGIPGLLYASSKISRPDILDEKTFFEWYDEEHIPELIQTSGFDSAFRLVDNNPGSERPYLAVYPTKDFSFFHSDEFAGMKSLQSDKLPGTGATAEVMDSVSRFDKLVQIYDPTKKGPGHTKCIISAQMKSASGPAAEEDIDAWYRAEHLQLIAKSEGYLRTTRYKLAFSAHLPPPAEEEAKPPVWLALHEFETETVDPGKLRELTKTDWTDKIHETTEGILTIYKLAKGFGTQDLFHGVEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1P1</accession>
    <name>A0ABR1X1P1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004308</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672241.1">
        <property type="nucleotide sequence ID" value="XM_066808623.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041683"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032862">
        <property type="entry name" value="ALKBH6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="203"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="343" mass="38072" checksum="A0892414CD1C6C7C" modified="2025-10-08" version="1">MRTKLVCLSNLTTPALPFCPPSLLLLFLTFPSALLRTHRFPPHVWRELDSIRSRLPSVGTRTPVTEAPPSTQSSTEPCLVLSLRAPSLAVMAADSAPNISLPASLDDARIRGMPLAAYYIPDFLSADEERAILDRIASVPKPRWTQLTHRRLQTWPSELIQNRLVDAPLPDWLNDPVVSRLQSIPISLDPDTGHIFSSSPHCQPNHVLINEYPPGIGIMPHKDGAAYHPTVCTVSLGSSLVLDIYKSKNDGALDTTPVCRVLQEPRSLLITTEDLYTDYLHGIADVDEDLDLSETTVANWGLLRSKQPFVDGRNPRGLRTSLTYRDVLKVTKLGNKFSILQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X276</accession>
    <name>A0ABR1X276_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="10">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_004462</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672395.1">
        <property type="nucleotide sequence ID" value="XM_066808777.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041837"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF55">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8089501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="665" mass="75989" checksum="828B83AB9AD5259D" modified="2025-10-08" version="1">MIRDPFNIHRNPASGLAIIRTAATRAATDLGEKAVEASINAIEKGKQAVDDMAFSIPKNVPSFSNPQRQLEDRVWGNGGRSSNFLNPDRNALPMYKDKPYAYPPSQRSRPLWRRKRVIGLFFLLVVFLYHFGGFSKHHDTFTSRPSWSWLKKTESGANVDWMERREHVVDAFKVSWDSYHRYAWGHDEFHPITKKGRQMVPHGMGWIIVDALDTMILMNLTSRVSQAREWIAKDLSYDQDHDVNTFETTIRMLGGLLSAHYLSNEFPQLAAQKDDDPGAPGEDLYLEKAKDLADRLISAFDSPSGIPYASVNLAKYEGLISHADGGASSTAETTTLQLEFKYLAKLTGEKYFWDKAEKVMKVVDDNGVEGGLVPIYIYAEDGKFRGENIRLGSRGDSYYEYLIKQYLQTSKQEPIYLEMWDEALQGVRKHLVTYTEPSGYTIIGERPEGLGKPLSPKMDHLVCFMPGTIALGATGGLTEAEAKKLPTWTKKNEDDMRLARELMQTCWVSASQPPLHFDPDPKAEWRKDFTVHSNDVHNLQRPETVESLFYMWRITGERKYREWGWEIFKSFMNYTALDDEGGFTSLSNANTIPPVTKDNMESFWLAETLKYFYLLFSPNDLLPLDSVVINTEAHAFPRFQMSPLFSTGWERKPRDKDGKIIEHVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3D8</accession>
    <name>A0ABR1X3D8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004857</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672790.1">
        <property type="nucleotide sequence ID" value="XM_066809172.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042232"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF186">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="683"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="713"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="738"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="777"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="824"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="857"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="942"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="969"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1022"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1048"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1110"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1147"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="62"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="262"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="382"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="509"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="611"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1299"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1354"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="341"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="411"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="430"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="462"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="627"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1413"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1434" mass="157566" checksum="CFC1284681FE43DC" modified="2025-10-08" version="1" fragment="single">AATLSGFRRSLVRGSESAIDFPNHHEFPNTSSASSAVIRLVRYCDLDQQNDHAKAREQGFITNAADPFTQKRPDHKPLSEVDVSPRTSLQLSPSDMSRMANDMRPASIRSSGSKNGSSRHALLKSEVSQQHSSEKDLPAPPILTQTPSPTEEETKNNSSDKIDWEVVALNSKEHKPPGIVCIDPTLHAPGAHSKVHHPGLVSGADFCDQGTEVERESPIRTPETQRSLSPPQIITGRVFRTLTGGDICEAEVDVSEHFHQHHSAMTKVRPATQPVLQEDSHSGHGGISKVRPADGVDTRAFTRQSESLYDPHSSSPYSNESYNHQGHHPVSKEITAHAPEDPQPMPYPPASSPQPGHSVFKEEESSKAASYWGDIPLGIENKETQDATKEPSVKSGKAPLEGSPLVDVDNSKQPWLTTNTISEMPHSTHESQPGSNTRSFSVHASQKRPETQHIVTKRRRSTSYASRGLETTNQENKPSQQAQPFLPEGLDPRRATQWLRELLKYKKSNQPQLTQLPEKLHPRHEKHSHQSSLDASSKEVLTSVTTFSDKNAADADAINNAMKNLEQLLSEALHIANNVTEPQADACSLDGGASDDKVDFGMPLPQRNAVKRSGTDVSPPDHLHHNSAANPTRASLRQSAAKRAHELRNISLRGRSHVSIRDAHFSLTKSHKRQPIARDWSPIRILIGIYAGLVPSIQYFIVDTNHSAILGNVGLYIGMALPTFLCWPLPLLHGRKPYILTSLAVAMPLLFPQALAISSVRITFTNLWTMTLLLSRALMGVALGFAGMNFHSILTDLYGVSLMSRNPHGELVDSSDVRRHGGGLGVWLGIWTWCFIGSLGLGFLIGALVINTLQPSWGIYISIILIASVLILNVLTPEVRRSAWRRSVAEVKVGDQVSRRVARGEIMMHRVKDGPKWWGQEVYHGIALSLEMLRQPGFATMAVYLAWIYAQIVLIIVLLGSLTSRYYRLHSPLVGAAVSSVAIGALIAVPFQKANVFSRARYNPVATNSMTITSNFAWTSHLVRRAVFILVLPIAGAMYAVFSYGPPIPVAVPCLFAAMVGFLSCLAISECNGLLMETWDCSDLEPGMTGRSKSLKSAEKRTNYSSFPRVTAGYAVIHTFAFIFAAGATGIGGLARRNLGQRATTGVVAAILFVLTLLLISVLIRFRHVQIIPDSRTAEMEKWTEARRDSLLRRESAIAAAKASGRKDLSAIPEEDVGWRPLVIGNPLDKNRRMNILELGSLTRWSEIRKKNRLIDEGTHLNRQALEAARTELGHRGMEVYGDLQRSGAMVGELVRKVSKRSLRSKRSDTSSDEEGEQKYRAGNTGPVGAGFGHSHAAYPTELFTERECVMGQAVAEEGEESSSIDEPPMVRSRSQDHRSHQTPKVQPHAGFEQQEVQGGPYHSPADGEPETEGGRREHGAHMESKIRPTGDRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3Q4</accession>
    <name>A0ABR1X3Q4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004986</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672919.1">
        <property type="nucleotide sequence ID" value="XM_066809301.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042361"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052982">
        <property type="entry name" value="SRP1/TIP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633:SF1">
        <property type="entry name" value="GPI ANCHORED SERINE-THREONINE RICH PROTEIN (AFU_ORTHOLOGUE AFUA_1G03630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046576638" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="3">
        <location>
            <begin position="26"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8090025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="220" mass="21194" checksum="BF807BC48AA9FE74" modified="2025-10-08" version="1">MQFFTVPMLFAAMVAAKASFTNTDFDVEAGKPFKLTWDGASGPVTILLKSGPSGNLKTVSTLTSGATGKEFIFTPDGSLPKDMYAFEINDGTEPNYSAQFPLGNGAAPSSAASAATSATSTAAKSSYAVSSTFASSTITATASSSAAASSASASAPASATVSGSSSAAASASMSASASASASKSASSSAASTPTTLPNTNGAASAHAPLALLAGAAALVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X419</accession>
    <name>A0ABR1X419_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Serine/threonine-protein kinase Tel1</fullName>
            <ecNumber evidence="4 16">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">PG997_005114</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Chromosome</location>
            <location evidence="16">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 16"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673047.1">
        <property type="nucleotide sequence ID" value="XM_066809429.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042489"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05171">
        <property type="entry name" value="PIKKc_ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038980">
        <property type="entry name" value="ATM_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044107">
        <property type="entry name" value="PIKKc_ATM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021668">
        <property type="entry name" value="TAN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11640">
        <property type="entry name" value="TAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01342">
        <property type="entry name" value="TAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="16" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 16 21" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="16" id="KW-0779">Telomere</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="19">
        <location>
            <begin position="1691"/>
            <end position="2243"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="18">
        <location>
            <begin position="2300"/>
            <end position="2647"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="20">
        <location>
            <begin position="2658"/>
            <end position="2690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="854"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="2614"/>
            <end position="2642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="864"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="874"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="2620"/>
            <end position="2629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK8090153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2690" mass="301195" checksum="73A1FB2786E6604B" modified="2025-10-08" version="1">MAPSTRVRGESIEDVRQTIDNGNLKDRQAALDDLIFFFSKKTKAADLSALNDKHYHQILDTLFRCALSEKQSFLGAKKTARASAPAKLAKCAEALRVVIESGASRLKRKTLVAIIDHITQTLPGPDADLVEPLLQGYIKALMALLSHPANVELLATYDAEGWYDCVDFSLQTITRYIDAGDTDSDPYRSSPAPTAQTFSMTFSTPRSSAISSQQRNTSHMEKSRLHDLLNCLLSLISAANAPLQKRVKDISSIGIQVLKLPSSGVAASLQVAFSVINVALSYAQTDDVEYAGSIAAELVPLIGRWWQAKIASKDDALLNNLQVEMLKALYSMHMQLESLVQKNDSTILASVEDLCDLLWSAYTRRDSRSQLQQDDLSYSTVPRHQHSLATHVFGLRLHNIEAERRWAVVHTLSLMEATLWRASHLTHTRDEDEQDQPRKKRRMASGYTRLRQRLLSPDLNVQLAALQVVPFFIANVRVAEAFTVETLSSLVNLTAHKNANISVWAMIATASIAQTEHAKGEALAASWKQLWFIASRNLSIQGTCRAACLLLHMIVSRDLVQFHDISDDVHNIVTAADVNGPAIMVDSSVILMTKLLQLTNHHLPSTSFATCSHVVRWLFLRWDPADSIFTSFYSTLIEPIEIINLLRVACGVSHMILTCLPQSVVGPLGEAWGLLQERKDIIRYLLLLPDDDKATSEAQKLQYFEAAPTSRAAQTSDTYAVRKLIAELLYPRFQELVALCATWNARGDGSSHISPEKLESVMGFVTASFFCLPLLTEAHVQQTQNLEASLFDLLKNTLIAASLSADSRFLHERVLRIIRPYIPSCRECDISSFAKESPQALNFFSKLSDEYQQLEKQTSGHDEDGMDLDDEFGSQESRSTTMTKGLEISRRETVMLDANSFHTDTKQRLHLLKILRDDTGQVGLVPQLFLESFLALSDEELLLSKQLGRELLTGDAVISPDDQKLLIERFGTIMASSTYSSCETALALVLDVIEGLMPSWTDKRSGICDEVGDFYRFFVKNALPNNLLSDRIQTVLARLMLSLTMIDEKYPEALGIPNTIESVLGILELGSVPVKFYIANRLPVVFGRFVLKAHDDVFAESILHNLPTEPDFPEGISFRLYVLAELAQNWPTLLRRCVYHLFETAGQIHDSAKHASYCLRKIATSLQLESSRNLFKLFAPQLLYTWLSEDSIENIPFEIFGYASLEELLKHAQSEAAAIMMMRGHDQELASLARHLGLDPVQLVQRSFSKVLAFGISYDLSTRQPENAQKAESRIRKLMGRESYLENVYINFVDTIGQFFLLIDQEGPVEHSWSKDESLVYAAEAMAEIKGFGHSEVELAPNQQPTFKAKHLSRELALLCSRTESSGNAERDTHESNLLLEILRDEGNKNQLLSETSRKIALGILCKDFHVPDSFRSDAVNSDDDATAISTAVWKSSSQAQYTGDDYLVWAARVIGRSFSASGNIDLTLLRESHLTDYLQRSSGGSSSEQGLLDLMQSLTGDIHCFTAGIVESSLRTIVSEAAAQEDNDLLEACGRVLSQELLAASDWLPYRTPPSDNSPAEARLDSVVFSPEALEDPAWAQHVTIHLIQSVPGCIILDAMPQVLEHVQNFAEAAFPFIVHLVLLAEHGQRQSAKKSFSAALREWLKLTSSKAKDNLSLIINMLLFLRTQKFPGESSIADRSQWLDIDLTDVASAAARCGMHKTALLFVESSANEGARQSRRSSAVRAQDSTDVLLDIFENIDDPDAYYGLPTSASLENVLARLDYEKNGSKSLAFRGAHLDSHIRKKDPTATSDGRHLVNTLSNLGLAGLSHSLLQSQQNLHPDSTSVDNMFDNARRLEIWNIPAPPLTNNPSAILYKAYQGCYQAVDMNIARQSIYSGLKSIMENAISRDIRKANVRHNVAVLAALTEMDDILHVADATELDDLLASFEARSHWMKSGRYEDVMQILSCRETTLSMLGHTLPIRTRPRRDAAARLEGANALWDHQEMVSSIRMLQSIEATSDLKKQTVLVQRSDLLAKIGHQVSVAKLEKPDNIQKNYLQPALKELRGRIDGQEAGKVYHQFAMFCDEQLQNTDSLKDLSRLRHLREGKNDEVVQLKGLVASAKESQMRNRYQIHLAKAKQWLDLDDQELRRVEQSRSEFVRLSLENYLLSLTASDEHNNDALRFTALWLERSGEDMTNEAVKRYIDKVPTRKFAALMNQLSSRLVDQSHQFQRLLIELVYRISIDHPYHGMYQIWSGMRSRTNNKDDVAVLRQRATEKVGKKLGQTPTVSTIWTSIDKTSKSYHMLATERDTSRYKAGQKIAIKESSAGLRLLQDLTKYQIPPPTMQIELSADKDYSRIPYVTKLEDSMSIASGVSAPKIITLVGSNGKRFKQLVFAAASSVLKLHRSTQQRNLGIRTYKVLPLTASSGLIEFVPNTIPFHEYLMPAHERYHPKDYKGSQCRKEISQVQNKSVETRVATYKKVTDRFQPVMRYFFMENFSDPDEWYAKRTAYTRTTAAISILGHVLGLGDRHGHNILLDSVSGEVVHIDLGVAFEMGRILPVPELVPFRLTRDIVDGMGITKTEGAFRRCCEFTLDALREETYTIMTILDVLRYDPLYSWSISPVRMAKLQTPRTDEGEEGPTDAEIDSRKKRGVVNEPSEADRALEVVRKKLSKTLSVSATVNDLINQATDERNLAVLYSGWAAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X420</accession>
    <name>A0ABR1X420_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673056.1">
        <property type="nucleotide sequence ID" value="XM_066809438.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042498"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050667">
        <property type="entry name" value="PPR-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939">
        <property type="entry name" value="MEMBRANE-ASSOCIATED SALT-INDUCIBLE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939:SF14">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="646"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="798"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="421"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="911" mass="101012" checksum="45FD4EACBBF58470" modified="2025-10-08" version="1">MKATPNSICMLCRHALATKAARRAAVAAPAPWSPQASSYSTATATGAPVPPPAAADGKEASTTAPPPNPGQNEDVGPHGNGGRGYRNVLVNGERKSKPSATIVQESRTRRHSQPKSDSDMNALFQQIVGQSKNHNAASAEGHHARSRDLGLVADIARLESMVDSDLSVSRAYSVLKTKLYPAIRQEGVTIPQIFFPVVSKLMLKMINVKNKNMTANDLPPVAEIFRVCLDVGEIDPRLWSKLVEKLVEGLCEMSVSPADYPSIEAFEKHLATRDEMLTDLVESWKVLSLPKHAVVNPMDKENDIIDGFWFPRLEKSSAYRLPGSGNFVSAFSSLFSQYDQTKLGPRVSTLAIATYALLLDRQRSNANVRQGAARFMAKIAYMISTVRLRSEKLGEYLSQSSAASPATARYIMEQWPNISESLDGGKENTHPRSPASRNAAAGHAKPYSPHRVSIEKRLSRAYGTRHLAEVDRIWHDFIGKPADFTPERAAALREEQDIFNSFINTYMALNDPDKAIVVWNTLPRLGMKPTLKTWNVMLDGCRKARNLNGLNTVWSRLQASGLALDIPIWTTRVAGLIDCGDPKGAIEALEELVKRWHLGQKGQQSDALKLAIEPINAAMAGLVRLDKLKAAQSLLSWSSRQGIRPDIVTFNTLLRPLIRDGREKEVKGLLETMKTLGINADAATFTVVLDGTLANVPLNDYQSQAEVVRSVFETMEGAGLRSNLHTYGKMIYLLLRSGDRAQESVKIVLSHLWSQGYELSPHIYTMLVEHYFARQPPDLDAVNGLLLRRRLLDYDDMDRVFYDRVIKGYAHVGELGTALDIYRKLHAAGFMVELETQFDLLRALVRTGTAQGEHEARQLVEGTMARFKELHAEDWQSPQHARFWGHAFWHLAVRSGVLQELPVTTDKMAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X463</accession>
    <name>A0ABR1X463_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Actin cytoskeleton-regulatory complex protein PAN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PG997_005125</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673058.1">
        <property type="nucleotide sequence ID" value="XM_066809440.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042500"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013182">
        <property type="entry name" value="DUF1720"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF173">
        <property type="entry name" value="ACTIN CYTOSKELETON-REGULATORY COMPLEX PROTEIN PAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08226">
        <property type="entry name" value="DUF1720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="10" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EH" evidence="18">
        <location>
            <begin position="209"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="18">
        <location>
            <begin position="479"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="19">
        <location>
            <begin position="512"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="610"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="799"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="885"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="709"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="65"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="800"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="885"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="919"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="978"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1039"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1085"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1124"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1156"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1170"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="1192"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1227"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1280"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1331"/>
            <end position="1341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK8090164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="22">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1372" mass="148487" checksum="4D64C5CC28E632C6" modified="2025-10-08" version="1">MYSNSNSFMGGANSLRPGQQQQYGNNQFGMGQQQQQQQQPGQQPSPFAPQPTGFGQAPMTQQYTGFPGQQGMMQPQATGMPQQQQQPQQGLQPQYTGFPGQPQPQQSFQTGAPPMPQMPQQFQQQYQQQQQQQPQPPQNLGSFSTPTATGAPSIPAPPPKPMTAQPTGFQAMANSFKTGGNQNQGPPVPEKRQANKIPNIRLSFITASDQAKFETLFKSAVTEGTTMSGDKARDLLLRSRLDGDSLSQIWTLSDTTRSGELFFPEFALAMYLCNLKLVGKTLPPALPENIKNEVSSMVDIISFSIPEDTSSNNTSDFTRQNTATPPVIHHPQPQPSNAQILQAQMTGFPGPQMQPQPTGFLGQNQGMQPQPTGMQPQQTGFPGMNNPQPTGYNGPRPPMPPMPTGYAGGLGVPSAAPLNAQPTGRPGQWGLVNGPAGGLPNMDALQARMMPQQGREQQDYTTTGLSGNAVIPWAITKDEKRRYDEIFRAWDGLHKGYVTGDQAIEIMGQSGLEKPDLERIWTLADNGNKGRLDLDEFAVAMHLIYRKLNGYPESLGAVKSMLNQEADFRKNSGASLLPQKTGVSYLKNHSFRGGSSPGAGGRKDATVFKNNDEAVGYRSSARRRVGGGSPRPQSPGSVASNDDLSVEQLKKKIREKQVLLDAMDFKDEAAAEEDDILDRRDRREADELYRRIRRVQEDIDNHPDAALMSGDSEAERRSLKRQLQNLTDKIPELASQVRKTEKAIAEAKLELFRLKDAKAHPGSASTIIGTGPGGAITESDRLKARAKAMMQQRTAALTGKKIDAGDDDADAPKRLEEESLKARTEKENNERMVRDVEDSVRDFAKGIEDNLKEGGKTSANEHETRRWNDALGVEDEVRDFIFDLQRDSRAARVRAQDRSGGRKATAEPVKAEAPPRVESPSAARTATPPASGGSYSSYKTPEERAAFIKQQAEQRMAERLAALGIKAPSKPGETAAQRMERERAERAAKLRQAEEEDARRESERQARIAEEQGVPPPAAAEAPKAAGKKPPPPPTRKGAKADDSAKHAEEEAAKKAEEERLNRESQEQQRETQELEAQAAEAETELEKERAAADARLKALEEQVKAGKLKKEEEKKKKKAAMAEAKDKEAKLAAQRAEIEAARQRELELQRQLEAMDGDDSSSDEDEGPQQITPQASTPTISGSQEIERQATPPPAPSAPAPPTVVTSPPSESESRNPYRRMMSTDSASAPAAPAAPAAPAAPAPPAQPEVSTNPFHRMTQAAPIAPQPTGNISRKRPDTDDEWGSGNEEESDDDSDDDRPQAGAAQLASLLFGSMGPPRPLSAAGNRSQTASPAVASPAVASPPAPTSSSRCGGRGTIECSPASPSASCHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8K0</accession>
    <name>A0ABR1X8K0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673824.1">
        <property type="nucleotide sequence ID" value="XM_066806528.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039588"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11577">
        <property type="entry name" value="GH71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005197">
        <property type="entry name" value="Glyco_hydro_71"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03659">
        <property type="entry name" value="Glyco_hydro_71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045633622" evidence="2">
        <location>
            <begin position="25"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="668"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="961"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1118" mass="121492" checksum="E86D20AE4E0CAD0A" modified="2025-10-08" version="1">MRGAQKLTLLGGTLLLATQVASKAAIAHYMLGKVTEEHVKTDLEKAKAAGFDAFAMNVGCVEPDWVDEVLGYMFNNAAAAGMGVYLNMDLYASGDACWNGASCCDYANDYTGIWNKYKNSNGWFKIDGKNLVSTFSAANWSRKEFNAWRSRWDEGNLFFMPDFDNTTGYWEGAAGWEHWGETVDGIASWESSWPEYAGHGGAFPGDVGPDLKPFHAAQDHGAEYMIPISPLQYKAAYKTNLYRLGDMNLPVRMENILAMSPRPNYVQFQTWNDGPESHYIGDIWPEQNHDYQPWKYMNPDRYDHRLRLATPCPILQQCVPEGGSTAASMDTADGKIAEGAIWYPSFPRNTECNGPDGLYSEAPTNYKAGVEGVYFAVVMKQGLAPGHTLKVWSGNTETPAVYDLQAGLNYGSAEVLNRGAQFLEILDPSGKRVASAAGGMCVAASCPRGIAVRNYHVVGVEVGDQGATCTPWPREQDEPDPDPDATKAPPPSAQPTTTTAQGPPPEETDGAIVKWLNNHNKGYPCKDEVEKAKSEHRTTSYGCIGFWPGAKSVPWERADPYSEWVALGHCTCDDPVLNLVGDTFLEALPVIAEVGCYVLMSSFKLVLDIALNAIPEGKALTAPMRPRRGLRPLAEPCGNNDLVPDEVKNVFDTLNSIADAAAGFKVPSKIGKGSGRRGDEGNPGAGKPKPTKTNGQQTTSKRPSETSAAKCSLKPANAVGRQGAGVVTSRECNKGATTTHAYTITSLAYAATAKPTLVAATCSGKWGQACQHYSSRHLGASGPDLKAAATDAWARQHGGAGWQSAAYRDEKLCDRAEYPPTYLMGGVGKADSKQCGVGPNQVVRWVPREQNRGAAHMWNNICFDTPLGAMSDAEMYEAAKNKNFGAKTKVRAPTKTEYTVGVTVAHIPQFTISSWEHKATKDDGLWDNPCWPKEITPNDPGFALLESDPWYARNSKKPAFDYSQPYAPGTNGPSNGPAPVQRRDWAVEGNDPFNNGTFSTVTKRDYEGNGPGIEAELYLTENPENAEVQEFTIGPRIGQGADGSIYTVTVEADGWDPCQTWVLKKDYVSIRDCNHEYAAYAALENHGIAPAFGAQVLDYETDDMVRMGLILGTSRRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9J7</accession>
    <name>A0ABR1X9J7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002419</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674030.1">
        <property type="nucleotide sequence ID" value="XM_066806734.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039794"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8092058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="90" mass="9256" checksum="0C5264D420E303E8" modified="2025-10-08" version="1">MIAQNPGTATVGSSSAKQVGGTAPFLLFCCTTSFGAQKPTWDSVLPHLKDVTWSNLAFVRELGGTVILASLDSDGPGLIPATAGAFSSWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9U8</accession>
    <name>A0ABR1X9U8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674218.1">
        <property type="nucleotide sequence ID" value="XM_066804445.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037505"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="498" mass="56120" checksum="7F5F57612C63EBC8" modified="2025-10-08" version="1">MDRPHTSQGFGHVVYQIIYNIFLSPLRRFPGPLLYTATSIPYDIANARGDAVTVLARLHDKYGPVVRVRPTELSYIDGHVWKDVYGFRSGKEEWFKGDVIHYLNGVPGIISAPKDAHRRYRRSLAHAFSSQGLQEQSPRIGTHVDRLVEGLGQHSEAGPIDMVPWLSWVTTDIIGDLAFGESFGCLENQKENAWSALTSKILRPALVIGIATRWHMTLLAPLLYPRDLFKGLMSTGEELREKLRKRLSRGDFFDRMLKHGLIVEDKAAFKETKDGQEGVTFEELESNAQDMVFAGSETTATLLTSTIHFLIRNPAVLAKVTQLVRATYGRDEDMTIASTAPAALPSRSGSMTRCPSSRRAWHRGVGDTVDGVFVPEGTRVFCAKYVAHRSALNFARPHDFVPERWLQGKPAEFADDNRHGVFQPFSFGPRNCIGMNLAKAEMHLILAKLLWHFDFEHPEDGDDWDSWSIGQKVLFLWIKPPMKVSIRKRKNLEAENAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAI3</accession>
    <name>A0ABR1XAI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Superoxide dismutase</fullName>
            <ecNumber evidence="2 7">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000272</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 7"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674360.1">
        <property type="nucleotide sequence ID" value="XM_066804587.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037647"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050265">
        <property type="entry name" value="Fe/Mn_Superoxide_Dismutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404">
        <property type="entry name" value="SUPEROXIDE DISMUTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404:SF6">
        <property type="entry name" value="SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="8">
        <location>
            <begin position="40"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="9">
        <location>
            <begin position="129"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8093587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="234" mass="25422" checksum="4E4D84A3B1BCD270" modified="2025-10-08" version="1">MPIRMPTTALRTAGQAARGAMGARPASAAGALTFARGKATLPDLSYDYGALEPHISGKIMEIHHKGHHQTYVTNLNNTIESLAEAKEKGDTFKAAAMAPALNFNGGGHVNHSLFWENLAPANKDGGGEPEGNLKKAIERDFGSFDTLKTQINTALAGIQGSGWAWLAKDKTAGTLQVITRANQDPVTGNYAPLMGIDAWEHAYYLQYQNKKAEYFKAIWNVINWKKVAERLEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAL0</accession>
    <name>A0ABR1XAL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AGC-kinase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674390.1">
        <property type="nucleotide sequence ID" value="XM_066804617.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037677"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="696"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1090"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
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        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="706"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="990"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1090"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1110"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1136"/>
            <end position="1146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1210" mass="129723" checksum="654ED514DE99C46D" modified="2025-10-08" version="1">MLSHLRFHRRGPSNPTSPNPDSTSWDVQPAQLVPDDSSVPAPDIRPRSTTSAPQSQHAQARPQSPPLTSPPPPPQPQQAPPPPPSQAPPSLPPIARVASVSETEYSESVYSVYVGDPESHPREEPRSEPRSDARPPLVEQNSFLGGLKYRREQDAAAAAAATTSPRAGPSERSPSYSLDSRNSSRPNIASAVTSPPGRPPLRSSNAGSSFVSPTDLQHNTTTGKRPPGARVKTEPAPMVNQTVTPNPPKGKKSLPFLKNPMSTLLMRRKTSQNIPDLSLSLLNDRGKTSYEPIRGTRVHDFSAPRPKKPVSNNVSPMVPTEQTVPEALQPNKDDLSPPQRPAPPVPPKDDREQSGRSSASIRSRRPVSVDGGSMMQSESKSTALSASASRRITLMDPQDMRRKSSVPSSISTALSRNMSGMSGMSNKDVLSALPRHMKSTSSRFSFDMMGAANAEKLLEEKHRQRVQERQSEIPDHRDSRFDDFDEDPFEYDDLDYDDGLEERIPGVNADYDEEEEGIYEEPVEEYDPDNDQENFAGFVFQRSNPHSTLASPQDATMAATPRDAEGNVIGFAMTQGTPDINNRLSQLSVQAPEPSQPHSPVAQALLSGDSPTGLGIQGLDAAIHESDRSSPQQSQQKETSAPAPLPPLQPDDELYFGGAGLEGEGDGLAIDEALFDLEDTDQYGRPLPGVFASALARRQAAEAAEEQAKRESDDVTSRLSGATAITQSTAHTSVSVAPNQEPLPADNQLENNEKSSPDGLEQPVPGCAATTVMDNMAAYQAALAAAAHKAAASGKFRRDSDPPLPADVTITSPTTSGSDHSNDNINSFDDYEFDDGFDDGFGNGLDDYELDDDAIIAEANASALAHDSDGWYGQEFGFYAAPAQPIPTRNPNPGSDTSPFYGGFFGSNNGLARSKSGHLISREPNLTPITERSEYSNRNSIMSLMSPTTNRELSSLQSPGLAQLAMMADDDNMSLSALLRLRSKAWGDSQASLASSRDGSPSDRNNDISSPWSPEGREQIPNHDMYGRKNSAFSLWSQSAESGAASGSGSPTLTMSIPTLPNNSNVPPVPPLNPAAVGANPNLAAGPVPSAIPQPLFSPPPPPTTFPPVLEDEEVSAEDDFDDRASAASAVLKPSPISSADYSLSSPKPGVPSQKRPGMGHRHKGSADSISYIKEEGDGSEPRWVLERRRTAESGEIEVLEREIVEGGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB04</accession>
    <name>A0ABR1XB04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674541.1">
        <property type="nucleotide sequence ID" value="XM_066804768.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037828"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3110.10">
        <property type="entry name" value="protoporphyrinogen ix oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.20">
        <property type="entry name" value="Protoporphyrinogen oxidase, mitochondrial, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF17">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="23"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="534" mass="60546" checksum="D102CF27519B126C" modified="2025-10-08" version="1">MPMTSSTNWVPRKKVAIVGSGSAGIASLWALNRTHHDVYLYEAADRLGGHTNTVEWKQDKFRCLVDTGFIVLNEATYPNFINFLKKVRVPTIPTEMTFSVSRDRGKFEWAGTSLDAIFCQRWNLFSPRFWRMIFDIVRFNQFALDLLKIDVDGPNQVKTNGVSGTKGVVDETTTIGEYLDREGYSEAFKSDYLLPMTAAVWSTSPDKCSLEFPAVTLVRFMWNHHLLSTVAARPDWLTLEYGAKSYIDAVVRGFPTNHLFLNTAVKYVANDDDGRVRLHFENGKMEAFDHVILATHGDQAYQIIGPSATPEEKAIMSAFKTSENTAVLHSDIAHLPAQQKAWTAWNYLTLSNPWTGRDVDKVSLTYNMNILQHIPRGPFGDVLVTLNPLQEPRSETVQGRYSYSHPVYNPEAVRAQNQLHRIQNKRGISYAGAWTKYGFHEDGFSSGLHVAMEHLGAKLPFEFVDSTYSRGRQPRIGMRDHLLRVIILLIQVFVVQIFERVFSGFTTPTNAKRITNSTNRSNRRALVNGDRKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBP9</accession>
    <name>A0ABR1XBP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000727</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674815.1">
        <property type="nucleotide sequence ID" value="XM_066805042.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038102"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="64" mass="7156" checksum="2EC22DA556CFF7C0" modified="2025-10-08" version="1">MTIGTTTTNLLLPRRLYRSPSAQVPPHADAGRSAVGIEITYDRRVVDYCEDNGIVDWKIMLPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCN7</accession>
    <name>A0ABR1XCN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675169.1">
        <property type="nucleotide sequence ID" value="XM_066805396.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038456"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38119:SF1">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38119">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="407"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="470"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="54189" checksum="DB580FF337A7C4B0" modified="2025-10-08" version="1">MVSQPDSNPSHSLVRGAQSVVSARTSSRPHNEFPVFSHSGDVEIVIRAGGRENRYLLHRHTLTRCSGFFEASTSQEWSKASVLPLLPEAAPPTRELSRIGEDSGVSVSFGGSGTGSGRSSAEVARPRASSPGGSRKRWRYELDPGAGPDDIPMLVQKEADSSSSRALPPPPSNSIFGGGGGGASVGARDAIANTSSSRHKHTQIFYNYPPVMDGINIADAYVQCKSLLTLADQYDALAVCGPRVDHHLLQFQSRLWKQVAKYPVSYLRLGYLSRSKIIFQEALIHVVGQWPAGERSIRSAFPEVVLDIIEDKVDELEETIARIEGRLFRLNLTNSRGERVTPSTSYLDWLAVSFFRQWLADNTSPPLRRRHLRRRPTVAAAITTTTAAALVTMAQVAPQHRAPLLRRTPRRHRRRSPRWAGRTAPSARRAAPPHAGPLQPRQSAPVRKRVDELKSAARELVRPLMGTGLELELSNTGSGGKMATVQEGRQRAVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD12</accession>
    <name>A0ABR1XD12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Allantoicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675280.1">
        <property type="nucleotide sequence ID" value="XM_066805507.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038567"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15473">
        <property type="entry name" value="Myo5p-like_CBD_DIL_ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037986">
        <property type="entry name" value="Myo5p-like_CBD_DIL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052072">
        <property type="entry name" value="Vascular_dev_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027:SF6">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN YPR089W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Dilute" evidence="3">
        <location>
            <begin position="346"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="653"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="742"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="659"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="742"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="763" mass="86969" checksum="BF373024ACBAD901" modified="2025-10-08" version="1">MDIGDVDSGGFADEPRRTRDLPPDLPKSLNDRIIPKEAVAETEYYDGWQDTDYDPDVTKAMPDSDTRLMEMLAAQAQHHGGEGLVDPDEIANDEKRSTTEKENILQKSLAMAASNGDLVQVKRILGGDAKKYVNGHETVVQALVDAGVDVDKQDRNQWSALMWAMTNRHKGIAKILLDNGASADAKTSSGRTAFDFVPPDSEMSFYLHDNGYSIGNAGVTDDFYNPGFEQDRFEEELAENEMRRRMMMESARDLEVDLGNVGMDDQPEGSDDYEEEAQEFDWSRCLHDQMFVFQESDLDRILDIIITNMQPQRSPSQKPVPANMIFLSARYAHYHASSELLEKLLISAQDKINEVVEKHQWDMTILAFWMSNATLLLHYLKKDAGLVEATTEFQAQLAELINEIFILVVRDAERRMDKVLEPAMLDHETIPGFEDVTFQHEWKIFKRKKEVKQEPIEKRYRPPSPKARAKPAPRNVTSLMSSTLFVLDLYDIHSVITLQIISQLLYWLGAELFNHIMDNRKFLARTKAMQIRMNISVIEDWARANNRKPEHYEHGDTTATGETTMDAARRHLAPVVQLLQWLQCFSSLEPDNLEALVGTLQQLKRLSPQQLLFSAKYYRPEVGEKGLPKSAVKYLEAMQKEVDVKRDRRRTISPVHGSVPSTPIRNTSNGFDIETPGSAPNPEIEEYEMPEGINFDPALMLPFSLPSAMDMRVSYGAGFGGVNRERERKYIPTIPPEFLEKLELSGQRERPMFGEKDWENEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDF9</accession>
    <name>A0ABR1XDF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001391</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675479.1">
        <property type="nucleotide sequence ID" value="XM_066805706.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038766"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="160"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="332"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="414"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="488" mass="51009" checksum="768949DB55108447" modified="2025-10-08" version="1">MGDPSSPPDINVSNGTCYYTEHEKTKGNFIPCGNVAFGHWPYGQTAGNTYLAGCTDAGFNARACPWKSPLFHEQEWVAIQQCHPGTGGEDTVWGGCKVDANQTTLEKLPHASCDPYCSSSVLVDASVLPAFASLPSSAGGSIKWTSGFDPTATAAGVKSANATATSKSSLTSTASSSPGSSVTAPPTATETSPPPAATASPENSALTVGAKAGIGVGAAGAALLIMAVVLLGLLVRRRKQRRNNQAHLEDTSSSRPHPHQYDEPSNEQQQGQVMYYNYNINKTPPPATTTVRPTLSSLDSQPYVGYKAELSADEAQQRRPWDQQTGFKSELAADETTMPPNEIGSSDGHDGNGGANERESRTGGARGETSQGSSGAHHGTSGSGGGLSPYPSPHPSSAATAHSPFSAYSEVSTLYASSGGGSNNGGMGRWASPTPPQQHQRQQRHGDYPLEQEWPLSEGPGGSAQIHSFRERPQVRGGTWRSHGYDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDS5</accession>
    <name>A0ABR1XDS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675500.1">
        <property type="nucleotide sequence ID" value="XM_066805727.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038787"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="807" mass="85743" checksum="9A472DD86BCBCED1" modified="2025-10-08" version="1">MPYSDHLYSSGHAAAYDSDSDDGYGDEHSPSDGYFTASASSPGVPSVPNVPNVMVPDPTLRQQPETAAESKAREVEQDRLAALNTRRHGRPLGNASLPGAHSYSHLEHATAPSTSTRTQSTYPIFTPRTPLSSTSAYTPSSSSASALVAAAPAASSRLPLRGLPSSRGRSASVYSDAPPAYTPSPTSPLSPASPTNQARNYSTFSSANMGIEDERLLGRDPESMGSPNDEESGRPAWRQRVRRRLPAWVSWRTTLLASVLLIASVGFLASSYRVVKDDRGNTIRPSPAVPIKQPADHAPLDPPPPGAPHPDLPALQPLESTHCRNATFRFPEQIMAVNFNKEKYFSFVEEMAFHKGHDDVSIAGQVNIRKVDATGNPRVILEIVTNDPDLRVDVNADEADQMMKVTVPKHTEASDPNIRPCMEMRATIYIPENAELKEMGIKTVHLDILTLDDLSLKVAEYTRFVSDLGDIVSAAGNARTYTTAEKTPMTGVQDYIFVPAKSTYRFDSRLIEVQTVAGNIGGTWPLYDLLGLHATAGNVQASIAPKPVLESDPKPAVLSLSTVSGFLSAAEPIHELDQMPIREYLVDLKSTSGRIHGALAFSTGIDLKSTASDIAVDLLPVLDSSRVNATSPAQLETGTTSGTTAVRVLDPIWFAGWSASPPPAPASNNNSPPPLPHAAAGKRDNNANANTKPAAPITLTAMATLEQVRDTASAAGLGSQPLNCLQGVHKSTSGDIGLKYPASWVGTLVGDSTAGKLGASGKDVRIVKSTSGLGRSELIAYVGQNGGASLIRTHSMIGNLACQIGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE11</accession>
    <name>A0ABR1XE11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Inosine/uridine-preferring nucleoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001483</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675571.1">
        <property type="nucleotide sequence ID" value="XM_066805798.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038858"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43264">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43264:SF1">
        <property type="entry name" value="INOSINE_URIDINE-PREFERRING NUCLEOSIDE HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045398047" evidence="2">
        <location>
            <begin position="22"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="3">
        <location>
            <begin position="28"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="347" mass="36518" checksum="246034DC31FC084F" modified="2025-10-08" version="1">MRSTQVLRSALHILAVPIAACAPAARNLIIDTDIFSDVDDAGALLLAATSPNVNLLAVNINVGSTYSALAASAILAHYGKGDVPIGIVRPLANSSFFDTYAYELGEYASKIAYHFASPTSNASSSHQPLLPWPPSNAEKAADPVSLYRSTLSAAADNSVTIASIGFFENLSGLLNSTADSISPLNGTELIRRKVERLVVMGGMYPSGREFNFFGDDPALAVHVINSWRGLTPMVFSGGELGGNVFSGTGLMRDESLAGVSVVYVRRGAAVVGSVDGAVCDGGGLGELFEYGNEVGYNHVFANGSNAWVYDEAVTDQRFLRLRVSNETAAAELDQLYLAGARSATKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE21</accession>
    <name>A0ABR1XE21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arylsulfatase</fullName>
            <shortName evidence="5">AS</shortName>
            <ecNumber evidence="5">3.1.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aryl-sulfate sulphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001546</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an aryl sulfate + H2O = a phenol + sulfate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17261"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:33853"/>
            <dbReference type="ChEBI" id="CHEBI:140317"/>
            <dbReference type="EC" id="3.1.6.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675634.1">
        <property type="nucleotide sequence ID" value="XM_066805861.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038921"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16147">
        <property type="entry name" value="G6S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012083">
        <property type="entry name" value="Arylsulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108:SF8">
        <property type="entry name" value="SD21168P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000972">
        <property type="entry name" value="Arylsulf_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045870020" description="Arylsulfatase" evidence="6">
        <location>
            <begin position="19"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="7">
        <location>
            <begin position="37"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="605" mass="66869" checksum="4B96B7B7B5DF1D1C" modified="2025-10-08" version="1">MKAVVAPILLGLAGLAFAQSQKTTGPANDPAKAKSKPNFIFIITDDQDLRLGSLEYQPAVQKHIADQGTTFSKHYCTISICCPSRVSLLTGRAAHNTNVTDVAMPYGGYPKFASEGWNDKYLPVWLQEAGYNTYYTGKLMNGFSTATYNNPFPNGWTGTDFFLDPNTYVYYNVTMQRNKEGPRTLTGQYSTDLAASKALDFLDEALADSASGDDATQKPFFIGVAPIGPHSETWQGRFTTPVPADRHKDLFPELKVPRNPNFNPEVPSGGGWIKTLDRQNQTVVDYHDDYYRRRIQSLQAVDELVDGIVRRLETTPDVLANTYLIYTSDNGFHIGQHRLAPGKTCSIEEDINVPFVIRGPGIPAGAKWELPTSHTDIVPTLFELAGIPLREEFDGVPMPVTEAQQQGSEEGSAKSEHVNVEFWGNAILEGDYPGTGSGMHGMSGLNDTYKALRLLGDGYDLSYTVWCTNEHELYDLKADPWQMTNIYPSTSANSNDDSTTLLYGWPKDKLIARVDALLLTLKACKGAVCRKPWEALHPAGDVHSLRDAMAAEFDDFYVRQQPRVSFSACKLGYLAEFEGPMQPRILGDAAGGGGYSMEARWEDWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEA3</accession>
    <name>A0ABR1XEA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Threonine aspartase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675795.1">
        <property type="nucleotide sequence ID" value="XM_066806022.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039082"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04514">
        <property type="entry name" value="Taspase1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037464">
        <property type="entry name" value="Taspase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF8">
        <property type="entry name" value="THREONINE ASPARTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8095022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="628" mass="67520" checksum="08FB8BBA88421348" modified="2025-10-08" version="1">MSDSKQHLPQEGGQTINHSYHLGKRKLGQDKPGSSQPSRSQRVSGPSIMSYDGDFDLDPNDEFKTDIFPEGTEVPEWHNAQPVSDPALTAWLDGASDRKGRRWKPPVTAIFIHAGAGYHSTTNERIHLQACSDAARAGMRILKNGHPATEAVEAAIRVLEDKEITNAGYGSNLSIDGTVECDATVVDHYGRSGACGAVPNIKNPVTLAKIILESSIEPLSLRRVPPNLLVGNGAKDFAWDKNVPIIPNDLLISRNALDRYNRWREDLERAKLGEKTAEQVNARTNKKDQRDHTNAIMTGMWNEGQPDSPGQPSTPSENGPSSSPRNASNPQSPLPSPTRHLPKERGVLNLHLLGSLAAPKPVAPNQSVDASVNKRPRFITHHSNTGSQDSDGQEDDRMDVDKNHNSPLRESTASLTGDTGLPNQNRPAEPSNNVGAEFRDDLITDTVGAIAIDQNGFMAAASSSGGIGMKFRGRVGPAALVGIGTAIVPVSEDDPDGITVGAVTSGTGEHMATTMAAQKCAERLYHGTRRGPRGVDVPEDDESAILQGFVVNDFAEHPGVKYSTSTGAIGVMSVKKAPRGYYLYFAHNTDSFALASMSSYDREPYCVMSRLPEGSSRVAQGGRKISVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEI1</accession>
    <name>A0ABR1XEI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001711</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675799.1">
        <property type="nucleotide sequence ID" value="XM_066806026.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039086"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="28"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8095026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="256" mass="29228" checksum="F18DA7FD20C6065C" modified="2025-10-08" version="1">MPFLSSASQKVNHLFQDLMHPRAALSTSSTTEVRSPCTDIRESDDAYFIDVELPGVVTDDIRLNWTNSRVLLVEADAQRPPETVEEEEEAEDGGKLTRVWSHDDNCRQCTQQWHHHHRYHPEDRTASNIGQQQYLLQRQDNSKFKRSGSFGAFGGGNGISNKINSNNSGSFHKRRSSMFAFTNNNNGNNSDASSNTSWKHPFHFLMRERRDCAFARAFSFHVDVDQGHVTTEVKDGLLHMRVPKLFMDDELSEIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEK5</accession>
    <name>A0ABR1XEK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675816.1">
        <property type="nucleotide sequence ID" value="XM_066806043.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039103"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8095043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="23730" checksum="1C11C0BFFB4AC8C0" modified="2025-10-08" version="1">MIPRSCDKTVVDGLGPETARKKAREVLVQLRRLPAVPHRARAALCRLAGLGTELNTNDGGGWAHRHGAATPLDDDLVEFIPNQISEFRGAISNYWTAGALGELAIFCGIQLLLGLYYSFMGLIFLPIVSAASYPHGFASAASVALGQHFEKGIEVVTRLWRAPSQLAKCPFLPYPCEHDHGCVILPRRLVSLVVQEVTRTVSQSKTSTPVKLERDAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTD3</accession>
    <name>A0ABR1UTD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7871 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660756.1">
        <property type="nucleotide sequence ID" value="XM_066818568.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051628"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057193">
        <property type="entry name" value="DUF7871"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40620">
        <property type="entry name" value="RESISTANCE PROTEIN CRD2, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04318)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40620:SF1">
        <property type="entry name" value="RESISTANCE PROTEIN CRD2, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04318)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25277">
        <property type="entry name" value="DUF7871"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7871" evidence="2">
        <location>
            <begin position="8"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="115" mass="11438" checksum="6BB87BF341FA8F3B" modified="2025-10-08" version="1">MATEVAQASSTCCGKSSGGECVCAKQAKCSCGKEQALNCKCDKAASENQVAGARCSCHARPAGQCNCDRSATENAPVAGSSCACGARPADACTCEKSSTAGGAANPNETDFTTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV62</accession>
    <name>A0ABR1UV62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661418.1">
        <property type="nucleotide sequence ID" value="XM_066819230.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052290"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045085637" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="16"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="56329" checksum="09960C2AB0C7F572" modified="2025-10-08" version="1">MRFATLAALVSGGAASAIPAGAADPLRRRITDLTDPLPELPLPIPLPNPPTLITFPSPSTCASYVTVTESAALLTETATQYVTAIADTVTSTQISTMESTLETTNTAVITQFETSFVTETATVATETATQVITEQKKKRGQMKQRRGDSCKRRSSSSQASVTSSSATSTQSADVCTATVTASALKTTTTVTVTGSATATDLATVTSVIVATITTTVSTTDLETTAVPTTLAVTATTFVTAAAPPAATPTFVLKGRTGNVINQYVTASGNIQPMGSNFLTFTPDVAAASAFTLKDGAVVLALYPDHKLIHLDDATSSSFAFVASAASPQSNAACQLIGETTAGSEGSFTCPNGGSGLSVFAVDTNNPMDLMFESPAATTYARIELDYVVLPLPTTTPPRTPAFTLTGVGGTVDGQVLRIQGDTSTLFNSLVFSPNAGDAALLTLRDDGSLVPASLAADPANYAGYIGASIPGEGGSSISITTAAAAGSYLRVTCQLSDSSTDVGSTGLFTCPNQGARMHITADYMGYLMLATQNADLFEQISVRYNFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UX88</accession>
    <name>A0ABR1UX88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661017.1">
        <property type="nucleotide sequence ID" value="XM_066818829.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051889"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF24">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="26246" checksum="9A5FD93704E20F41" modified="2025-10-08" version="1">MAPTLILIRHAEALHNLTKDYQIHDPELTENGHAQVQELRANLMNHPVAQNAGLIVTSPMIRTMQTAMGALDWLIEKGVKIEADAGWQENSAKPCDTGMPGAAVALAPKFPKVDFSTLDPVYPDKRTPAGSHYFATRSAILNRGQASLRRLRDRPEKVIIVVSHSGFLRLGVTGCFYLNADYRIFDFEAEEQVGEDGVTPQIRLRQWEETKEKGGGMGKSWKDMVELGSGLPDEIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V337</accession>
    <name>A0ABR1V337_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_012342</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662348.1">
        <property type="nucleotide sequence ID" value="XM_066816656.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049716"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07417">
        <property type="entry name" value="MPP_PP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041753">
        <property type="entry name" value="PP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013235">
        <property type="entry name" value="PPP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051134">
        <property type="entry name" value="PPP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08321">
        <property type="entry name" value="PPP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033096">
        <property type="entry name" value="PPPtase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="8"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="10">
        <location>
            <begin position="260"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8065595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="459" mass="52047" checksum="7E59AB9F64F05B9E" modified="2025-10-08" version="1">MASAIDKAVAFKNDGNKAFSAHDWPKAIDLYSKAIELNDKEPTFYTNRAQANIKSEAYGYAIADATKAIELNPKLVKAYFRRAVAYAAILKPKDALQDFKDCIVRQLNFFAAIEVGDEPSAAEGLDVESIAIEPDYDGVKLEGNEMTQEFIDDMIERFKNGKKIHKKFVYQIVIAVKKICYDEATMVEMKIPDDVQLTVCGDTHGQYYDLMELFRLNGKPTDKHWYLFNGDFVDRGSWSTEIALLLYAYKWLRPQGLYLNRGNHETDDMNKVYGFEGECKAKYNERVFKLFSESFSALPLATLVGDKYLVLHGGLFSDDNITLDDIRKLDRHAQRQPGQAGLMMEMLWTDPQTSPGRGPSKRGVGMQFGPDVTKRFCDKNGLEAIIRSHEVRMDGYEEEHNGKCITVFSAPKYCDQTENRGAYINVGPDYKLNFNQFDAVPHPNIKPMAYANTSITSMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3U1</accession>
    <name>A0ABR1V3U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012607</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662613.1">
        <property type="nucleotide sequence ID" value="XM_066816921.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049981"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="255"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="493" mass="55987" checksum="2EAB9E323201C692" modified="2025-10-08" version="1">MVALYIAVIYLTVIFLTGRLLQQKVKAVKSSLSRIPGPWYGPLTTLHLRWLFSTGEIWKLVERSHAKYGPIVRLGPRQVWISDKAALKKILVKNDLPKVAMYAEISRDKFSPGLFGEIRHDPHKRLKRFLSPAFTVAYIDNLETYFKTTVRDLLDKYQSTIAEDPLAATKNGITVDLMDDLHNVALDISMGECSFGKGFGQTNPNTLIEDGVDEKVWKQIPRSIFDGLSKRYQLLRKIGLDIQFDWPAEMITVSHRRRAPDRGGQEARHGDGHDDARHRGPDGRDPAGGIGDDLWHAGVSVPGAGADPAARAKLMESLRPKPFSDQDGSEIVSSKTVRTDPEYEYLEACIKENLRLHPIASEMGRRTGNQWIELMGYNLPPHTVVSASYRDLHRNEKYWPQAERFWPERWLPEEKRDGAPAPDMDAYYPFSGGNHSCIGINFAWAEMRMVAANILSRFDIVEVPGQDIDFRQYITMQFATGHWKVTLKPRVHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V447</accession>
    <name>A0ABR1V447_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase family 125 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662710.1">
        <property type="nucleotide sequence ID" value="XM_066817018.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050078"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008313">
        <property type="entry name" value="GH125"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047:SF1">
        <property type="entry name" value="DUF1237 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 157 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06824">
        <property type="entry name" value="Glyco_hydro_125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028846">
        <property type="entry name" value="UCP028846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01149">
        <property type="entry name" value="DUF1237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047442765" description="Glycoside hydrolase family 125 protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="56223" checksum="AD093B8A911CE52A" modified="2025-10-08" version="1">MFRSSLSLALFAGLLCGALAQCPAYVDYSTQTHSPASSGKYALSYMRPAPGCRTYNLSEVEQTIEDMRSTVADPDLFRLFENTFPNTLDTTISWKGFARGNSSEELTFIVTGDITAMWLRDSANQLRSYKSFLQANGSTASLASLYRGAINLQSRYILTSPYCNAFQAPVESRLAPEDNGAARTDQVVPPYDAASVFECKYELDSLSAFLQLSSDYFEKTQDLDFFGKYQWVNAIRTLVNVTEGLRVGTYADDGRVNASPYKFQRTTTRASETLMNDGAGSPVQAGTGLVRSAFRPSDDSTIYQLFIPANMMFSSYLGRCAEIMAQLDGALSKQMDDLAASVRAGIEKHGKTSLEGFGDVYAFEVDGFGSVNMMDDANVPSLLSAPIIDYINASDTTYQNTRRFALSKSDPYFMHGPVISGVGGPHQGPGKAWPMSVIVTLLSSDDDEEIVQGLRTLVSSTDGLGLIHESINTFDAHDYTRQWFSWANGLFGELLLKLKERKPELLRTSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4C2</accession>
    <name>A0ABR1V4C2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661920.1">
        <property type="nucleotide sequence ID" value="XM_066816228.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049288"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="269" mass="28845" checksum="07B5F1CED477891B" modified="2025-10-08" version="1">MAPPTLTPFQDRVIAVTGGSRGAGLAVVRYLLERGAKVSTCATSETNLAAAVAGIEKDMGFEARDRVLTTVVDIGKNDSVKAWIDATVAKWGKLDGAANVAARMHSKVFPIEDFAVADLEDMLQTNVVGTFNCMQHELRAMRDGGALVNVGSQVTKYAQPGMSAYIASKMAVVGLTRAAAFEAIARGIRVNMVCPGATDTDMVRQPLLLPSGESFTCTEDANFPALMKRFARPDEIAAPIAFLLSDESKYVTKQEWYVDGGFYETSYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4K8</accession>
    <name>A0ABR1V4K8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012003</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662010.1">
        <property type="nucleotide sequence ID" value="XM_066816318.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049378"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF213">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045515731" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="359"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="621" mass="66702" checksum="0A3BBA91245EE133" modified="2025-10-08" version="1">MYVLQVVVFFFLALGYCRHNPILPRQAQLASDYEYVVVGSGPGGGPLAANLAAAGHKVLLIDAGGDYGDELVESVPAMFPFSTEYAETKWDFFATRSPDPAVEAQNRITSYRLPDGTVYTGLDPPAGAEPIGTLYPRAGTLGGCAQHNALIAIRAFDSDWDVVADKTGDASWNGKTFQELYQKIENCDYLPNSILGHGFTGWFHTALTSLLTAVQDLKVVSIIVSAGSALGVGITTSLIGTVAGLAEILLKDVNAPGRTITKGPYQVPLSMKNSKRGGARDRILDVANAVDILGNRRYHLDIKLETFVTKVNLAGDLRATGVSFMEGKSLYRADPRSGSATISGEGTVNATKEVIIAGGAFNTPQILKLSGIGPKDELSRFGIPVKVDLPGVGANLRDHIEISTISKSNKDFSLLKGCTFMQGYPEVPDPCLEQYLSGIGQTGKGVYATNGLAIGVALQSTAATQEDPDLWVYGGPANFPGFYPGWAADAVADHAHWVWIALKASTQNRAGAVTLASADPLDVPRITFNTFQDDLSRDQDLQAAYEGIRYARDAMDKLIPLDGSFVEETPGRDNVSTEAEIKNWAYTNSFGHHACCTAAIGGDDERGRFWTRTSRTWRDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4Q0</accession>
    <name>A0ABR1V4Q0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662914.1">
        <property type="nucleotide sequence ID" value="XM_066817222.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050282"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="554" mass="61236" checksum="B23255659DDE4C05" modified="2025-10-08" version="1">MVAASVALAGNSVVLSCMGNQIRSLQLLHSLCLVNRQFNVEFSPFLYRHVEINDDRELSSLAEATGCLRYTKEISFIGPLTGSKANEVFRRILPCIIARLEAFNWIEIPLATQTIHALQAAPNHIRELRIEYPEDATWNLLGLAVGPEEDEDENTKVASVENRKLYRVQDLSVGFSNLTELTVHNIHDDLPRWRRRLATTLARSPGLRALSLSLAVDAVARAANRERHDDYRRFFEELAREYVEEEGGAPLPLRILDCGTGVFPTEARRLRQLVDLSGLEQVHIQNVDVARDAVYVEVYANDDDDGDSSKSGIVFGTFLNPIACSRLRRFTACALMPDVWEALCAIDDRAFARQLAVSFRRQEVGGLELARLLIPHRQKAGADDGDKVGSYPRLPLPLRMVDLDLCRGDAADSGDGDHISVETVLGGLVGSCAESLEGLTLHLPGYPETAKLAGVMVPLIEALAHLSGLTQLVVKTERRYSASPPGFAIVIAEELAASAPRLRYIGVDDMFWQVSRVSSSGSGGGVDCIRLRELDKREQDCVELFTHTIYEPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4U9</accession>
    <name>A0ABR1V4U9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011836</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661843.1">
        <property type="nucleotide sequence ID" value="XM_066816151.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049211"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="145" mass="16864" checksum="C1EFA4E0F8D68D25" modified="2025-10-08" version="1">MPVIDSQAMASYEQPPNQSSGAETGRYRFHETPMPSLDDHMPDKHGLYHCHHSHKTAKTFKRKTELQKHLKTHEKPVYCPLSDDPDFPCQRGRAAEQRDMERHVVSHHPEWARLNGFATEKIQCGCGEKFTRDDNFKRHQKQCNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V550</accession>
    <name>A0ABR1V550_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Asc-type amino acid transporter 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663061.1">
        <property type="nucleotide sequence ID" value="XM_066817369.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050429"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF512">
        <property type="entry name" value="SOBREMESA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="600" mass="64740" checksum="C9DC00AC62D54A58" modified="2025-10-08" version="1">MPANSSSHLQGYARDSLELASLASSSRGPGTYSDTDSRPSISSSRKLSLEQDDPLDENNPAGRPGHGRTYSTVSNFDFAPNLFPLSSSAAPGYTPIGAPTTAAHQNGGMGGASLEKTQDAHIHEWTGFDYRVNANVGSPGASLVVWVIAGVLAWTGAASYAELGGAIPLNGGPQAYLSKILGEMAGFLFTWVAVLVLKPGSAAIIAIIMGEYLVRAFIGVEAETINPWVSKSVALVGLVLLTFMNALSTRLGTRTNDMLMFLKFIALIGVTIVGVIVAVTGLSYSGPANIEWKSHGWFEGTSKDGAQWAVAIYAGLWAFDGWDNTNYVVGEFRNPGRDLPRVIHTAMPLVIICYVLANMAYFFVLPAATINSTNTVAVNFGQTVFGPIGALIFALIVSASCFGALNSQTFTSSRLVYAAGKEGYLPTVFARIGLRSTEPGLSSTRTRSWLSKRLHTMLGDEEAGLFFTPVNALLLNAVLTIMYIVVGEFGELLTFYGVAGYTFYFLTVLGLIILRVKEPNLERPYKTWITTPIIFCCVSLFLLSRAVFAQPLKTLVVVAFVLVGIPVYFWRIHGRDQVTKREIGGGEAAPSWKFWKRWTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5C8</accession>
    <name>A0ABR1V5C8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_012212</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662218.1">
        <property type="nucleotide sequence ID" value="XM_066816526.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049586"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044994982" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="25"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="36"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="170"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="595" mass="63850" checksum="2DF2EA56A60EB638" modified="2025-10-08" version="1">MENRLIRLALAAITLALFATPGFAKQAKSVDPIVDLGYARYRGYHDDDLDLDIWMGIRYAAPPVGKLRWQAPQPPPCNCSSSNVTSAVDPPPLCPQTGAFGTPAAYGFNSGPGDEDCLYLNVYAPHDAKNLPVLMWILPLAPLPTLMMRVYRWRGNSAFGASLTAWAPSGYLASPEIKAKGVLNAGLLDQRFAMQWVKQYVSQFGGDGNNVTIGGESSGAGSVMYHTTSYGGSGTVLFNNIIAASPWTPPAYRYDDEIPIGNYKAFAELAGCGAAASELKGRADAFDCLVAADTMTLQNASGLVSTTHGYFGTFAFGPVVDDDYIQGLPSRQLLAGQVAGKRILVGIPKQNNANEGVPLTNPEDAYDTFISSTFPNFTAEDKENLNTIYQINQAEPGNNGTRFDTLGDQGPTALTVSEMATGLQQTVFNIAAESLFDCPAQWLVKAFSSGTNTSYGSNNRSRQAWKYQYSVTPAYHGADLMSYFPVAPAGTANPNADFDRAIQKIWGNFIVTGSPVISLADAKAGFSNATAPVDGDKIDWPAYTLSEPYQMDLNTTGASGSGIVNTFRLVNATSWEGGRGERCAFWRDVAPRVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5L3</accession>
    <name>A0ABR1V5L3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Aquaporin rerated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_013220</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663226.1">
        <property type="nucleotide sequence ID" value="XM_066817534.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050594"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF283">
        <property type="entry name" value="AQUAPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8066473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="275" mass="29880" checksum="424CA91A8002AFA9" modified="2025-10-08" version="1">MGGRPLDDRSGDHQHHQHRDHNHTYTTKLQQHIVAATGEFVGTFMFLFMGYSGHLMVLDQVGTDKNSVANTSLGFLQTMVVGFTYGFSLLVSVWAFYRISGGLFNPAVTLGLCLADQLPWTRAAFLMPTQLIACMCAGGVVRAMFPGNLAGVNTILAPRVNIAQGLFAEMFFTAYLVFVVLMLAAEKSRDTFLAPVGIGLALLVAEIPGVYYTGGSLNPARSFGCAVASATFPGYHWIYWVGPCLGAMLAAAYFRFVKAWHYEEANPGQDADSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5Q3</accession>
    <name>A0ABR1V5Q3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA polymerase II transcription factor B subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_013282</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the TFB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663288.1">
        <property type="nucleotide sequence ID" value="XM_066817596.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050656"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040662">
        <property type="entry name" value="Tfb2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004598">
        <property type="entry name" value="TFIIH_p52/Tfb2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00625">
        <property type="entry name" value="tfb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152">
        <property type="entry name" value="TFIIH, POLYPEPTIDE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03849">
        <property type="entry name" value="Tfb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18307">
        <property type="entry name" value="Tfb2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor Tfb2 C-terminal" evidence="10">
        <location>
            <begin position="410"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8066535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="482" mass="54288" checksum="5D966E0AC3240B4F" modified="2025-10-08" version="1">MSVNTNSLQLSDYLEKLPGTTFKRLYQQPSTAFAIFRRMLPHLAKTFVMAMLYMPTPFLISDLEIWVKPTSKRQKDQALATLRSLHIIQSAGPQSMTLTTNFRNSLRLALEGGGDHHSFGVPSTLPVPSDVDLAFLDRYARKKWDDILHYVVNSVEYSDMRDKDTSGGGPKASVKELLIAGRLVEKRSVATISITQAGFTFLLQEANSQVWTLLLLWLEAADAAGERAGMDSVDMLSFLFLLASLELGRGYSTNALTERRRNMLPYLVDFGLIYIPPHDHQQYFPTRLATTLTSSESSLRSVSAGFLAASEGGISDAGDKNAIILETNFRVYAYTSSPLQIAVLALFCELKMRFRELVSGKLSRQSIRKAVDMGITSDQIISYLATHAHEQMHRLAAAQKKPLLPPVIVDQIRLWQLDTERMSVCPGFLFKDFESVREYEDMANFAGEIGVLKWRNDRKGMFFASKVEQIKDFMKNRRKAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5R4</accession>
    <name>A0ABR1V5R4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662142.1">
        <property type="nucleotide sequence ID" value="XM_066816450.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049510"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="136" mass="16379" checksum="D89FB48DD3BF2B74" modified="2025-10-08" version="1">MAVVVQHLPERSRREPLGTMTNRVLGQEPREGKHRLLERLLQWGLPQATDADDYEEELQEEEEEKDFRLVELFEYEGEKRQRLQKEYHLQENQWFRHCMARTFIIDLERIDQVLGQALGRGRSLPSTHTPFPMYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5Z0</accession>
    <name>A0ABR1V5Z0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662398.1">
        <property type="nucleotide sequence ID" value="XM_066816706.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049766"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="203" mass="22014" checksum="8AB3AB33E14B28F6" modified="2025-10-08" version="1">MSSRHQRPPVAMVEDVDDDDRVIEGSGHYARSNAFQSPPGSPLRQQMNTSKKKSSRSRRDSLMSPPGYDLDSDLPSPPSKPSRRDSKTEKKRSSMGSKGKTVVLKEDPRPRRPSTRTAKTAPGPPPRGLSDESQYYGIPSQTIIPSDSRPRAATRPASYYGSSRPPLSNSAYYGGSAPLGTSFPPPQWNGGPPGMPPPMGPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V699</accession>
    <name>A0ABR1V699_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663458.1">
        <property type="nucleotide sequence ID" value="XM_066817766.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050826"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098">
        <property type="entry name" value="PROTEIN MAK32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098:SF2">
        <property type="entry name" value="PROTEIN MAK32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="1">
        <location>
            <begin position="174"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="373" mass="40238" checksum="E4A89E32B697A63E" modified="2025-10-08" version="1">MDSASDDISFVSLGMLVLDELHLPDGQILRDDIGGSGAWSMLGARIAMGHPDAQKVGSFIVAGHDFPDSVTQAVRRLGVTLEMMVDPTRESTEASWLLTMKTRRSCISPSRFSPRLLSYPAICSPRGPSICYFPLKPSWPKFPRLLSRRQAAGIREPTFIVWEPLPWKCTPENLEAHKEASKLVSVFSPNHLELLGLFGNAKPNSTDTPNDDGAKSQQAVIKKCGTELFEGVADGAWQGMLVVRCAEMGCFAKSAAGGGLSNMFRPYHIDQKAVVDATGAGNTFLGALAVSLVAAAQKTDSSEQATQQQEVTAAAPVMGDASQITETIVRASVVASFAIEQIGFPDRTLVAGVERWNGDTFTRRYPLDGGKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6C7</accession>
    <name>A0ABR1V6C7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">RNA binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_013506</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663512.1">
        <property type="nucleotide sequence ID" value="XM_066817820.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050880"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06133">
        <property type="entry name" value="ERI-1_3'hExo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12452">
        <property type="entry name" value="RRM_ARP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051274">
        <property type="entry name" value="3-5_Exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047201">
        <property type="entry name" value="ERI-1_3'hExo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034351">
        <property type="entry name" value="Nrp1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044">
        <property type="entry name" value="3'-5' EXONUCLEASE ERI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044:SF61">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="253"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="11">
        <location>
            <begin position="352"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="11">
        <location>
            <begin position="441"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="571"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="485"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="575"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8066759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="653" mass="69299" checksum="D766D55878140254" modified="2025-10-08" version="1">MSNQPPQSPHFDRYVVIHVATTCDEHGVYVTKDSAEVIELGWILLDAKSLDEIHRENVLVKPINTPITPLCTSLTTLTWEHVRNAGTFRDAINRFDAFASEHLTSQNLDFVFVTLDAWDLRVQLPREARDKAVVLPPYLQHSRTFDLRTEYQRWQQHHPESLPFGPSMLSNICAALEVEPVQSSAPIKHNLPFHLQALAPASPRRAMEEAVTLARVLRGLIRKSQPRETHPDVLTRPMDARADVRAFLSERSKVLHMSGLPHDTTQSELESWFTQFGGRPIAFWTLRTPEQHKPTGTGFAVFSSHEEAAESLCMNGRALNEKAIEVSPSSSRVLDRAAEILTPFPPSKNRPRPGDWTCPSCGFSNFQRRTACFRCSFPAMNAGAQGGEMTGGGGGGGGSGYGYGGYGAPPMMPPPHHGGGHHGNMGHGGGRMGGGGVVPFRAGDWKCGNEVCGYHNFAKNVCCLRCGASRAGAAVVADSGYPSPMDSSSSYGMPGNNSMAGTPGPGPFASAAGPFGAGGGYGQQFGGPPSTYALPSGIGGGAAPYPSLNTHFGPAPGSHSAGPFDSRAAEAAFQSASNGPASAGPSNNFYSNQNESDPFSFLSTGIGGLSVSGGDARQNGAGAPLTSLRLKGIVISPAMAHCMSFELSGVVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6V8</accession>
    <name>A0ABR1V6V8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663653.1">
        <property type="nucleotide sequence ID" value="XM_066817961.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051021"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="249" mass="27668" checksum="9C560C6B5B481377" modified="2025-10-08" version="1">MASPPFRQPPGDYITNSASLPQLKPLGRRHHPSIHTLIHPFLISFSLKQHQHQPAATSPPHLIPIPACPELSAPQRHHHHGPSPLLRRRPPRPPNRRHLLVPGPTYNLTLGLDRTLPAKWPCTISRGAHYSVYVTYTDAAANGTVIHYAAARSNPAVLADGWTGLLPFVFNIPYGRIQPDSEVEITLDWVPHKKGMRRGTRSHTFFYKAAATDRPNGRGEVNAATTASEEGVVAVEDRHRENAYLICQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7I7</accession>
    <name>A0ABR1V7I7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663907.1">
        <property type="nucleotide sequence ID" value="XM_066818215.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051275"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="164" mass="17497" checksum="2B1064662840BBEA" modified="2025-10-08" version="1">MAPQINNNDSSEKGPVVVNTTDLVHSSNVSGTTTLGANEKDVVETSMELGRNSSVSTPSTAHHLNPFDADIEALRSSDNLNRKSISATPPNPNCSVWPGQDHWKRKAKAAKRQNRTCNCMAHLSKRNRIIAKLLLGLLIIGIAVGVGVGISKPLGADIWKPKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7Y6</accession>
    <name>A0ABR1V7Y6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012931</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662937.1">
        <property type="nucleotide sequence ID" value="XM_066817245.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050305"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF5">
        <property type="entry name" value="GABA TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="55809" checksum="FF76DBCEA00EC41B" modified="2025-10-08" version="1">MGQSEKPTAVGTNEAEMLASLSQSASTSEENLAILQTRTRRLFNKWQLFALSLMYMSTWSAVPGNMYYAMYNGGPAAYVASYIVIAVGALCQTASFSELASIQPIAGAQYYWTYHFAPAGSRRFLTWIQGWVTWTGYVATFASSVNFGTAVLEGIIQLNYPDYVVEGGAPRSSVSARSPSSRWSTCSRSAPGVLNILLFVAFMIIFLIMAPKNSSDIFRQTNVSSGWESYYAASQIGSLSNVWLFIGFEAVIHMGEETKNAKKIVPQSLFWSIFSGVSMGFVTLLVTIFCMPPVEAILDAASPVIAVLLHVTRSQTMTTALGGFLYFLNASASMGNMTSVSRLTWAWARDGALPRWLGHVDGRYRIPFRAVWLTSFLVALLTLLNLGSETYIALGAITSLSSMAMYLSYAVVFAVVLHARSTTKGIELGPWNLGRWGRAVNVVALVYTVYVIVWLPFPQTTPVDASTMNYSGPMLAGVLIFAVSLWVVRRNRWEGPNRAVVDIALKVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V858</accession>
    <name>A0ABR1V858_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664131.1">
        <property type="nucleotide sequence ID" value="XM_066818439.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051499"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861">
        <property type="entry name" value="GLYCOPROTEIN 38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861:SF4">
        <property type="entry name" value="SH3 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G13610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="512" mass="51411" checksum="05593B11D8E5FD1A" modified="2025-10-08" version="1">MSDDPNPRVSNGTCYTAANKRLDSSFIPCGNDAFGHQTCCGKGDNCLADGACFGVHGDGDPGEYGHMLTYWAGCSDPEYEDASCPKKVVDQPWVALTYCDNDDGEWAICSQSGDPSTLQPGAYCSCTDTAKATVAFKDTKTLTNLVSLPQNTGDSMSFFPGYSLSKTVPTTAGGGQATKTSPAETMTSRTLEEKTSSVAPPPPLSPPAGTNTTPSSSTSSPSLSSSSGLPSSSGSSSATTFTDANGRTVTATVTRTATSPSDTNASGSNTGNGDGSSSSSESSGLNTGAKIGVGVGMAVGGVLLVALVFLLLRRRRNNSPSSKRSRMEEDGAYMPPNEPKVPMAGGAAILEADGRPAKPHKLRGELGEGTAAAAGGGGGRRPSTKLKSAHRPRPSDDSAISELEGSLGGAGVGAGTTGVGHGITAAPPGEELATVAELPGTDAQGRRLASDDSLVPAPLQVHHGGQGGQGAPSSTTAPGAAGAGTHAGSQGNSAAIDEGAQVKPWGARWRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8U2</accession>
    <name>A0ABR1V8U2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L34</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013231</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663237.1">
        <property type="nucleotide sequence ID" value="XM_066817545.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050605"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_bL34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="142" mass="15418" checksum="7C1F73B9E2F0083F" modified="2025-10-08" version="1">MATPCVRAALARLGSQATKSSQPQSHLSRRTFTSLPSLRPSLPSARQTIFRASQPTCAPVPTAAAPCASTGESVLDIVPKTAISSSPIFGGVQIRCGPRPTMATSSRLIRKRRHGFLSRIRSRNGRRTLQRRKSKSRHVLSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9T0</accession>
    <name>A0ABR1V9T0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Fumarylacetoacetase</fullName>
            <ecNumber evidence="3 10">3.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Fumarylacetoacetate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_013803</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10244"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="3.7.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="3 10"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663809.1">
        <property type="nucleotide sequence ID" value="XM_066818117.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051177"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="entry name" value="Fumarylacetoacetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069:SF5">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="Fumarylacetoacetate hydrolase, FAH, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Fumarylacetoacetase N-terminal" evidence="12">
        <location>
            <begin position="10"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="11">
        <location>
            <begin position="109"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8067056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="394" mass="42137" checksum="A5A5854C7A03B505" modified="2025-10-08" version="1">MAYTEHFSIANLPFGIASCSAYPEKAVVTRLHDFVVFLADLSLECSYAVKSTLTKPTLNGLAAVSKAELHQLRSSLKKALEDDAVVTKFGYKVGDVSLHLPISVAGFFDFSCSKDHVQNMEEAIFGKKGMPPSFLHYPVGYTGTSSSIVVSGTQVRRPLGVTAGGGSVSFGPTKAMDYELELAAIVGKPTKLGDSVSLEDADDHIFGLVLLNDWSARDIQGFEMKPLGPMNGKSFCTSISPWVVTLDALEPFATAAPAKDLPVSTFLSETKPKPSYDIKLEAELLRDEKPTTICKSNVSWMYWTFRDLIAQHTINGCNLNTGDVLATGTVSGVGDDEHGCLAEMTKGGKVQVELADGSQTTYLQDGDGVRITAYCGNGVGFGDCTGFITPARSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAC8</accession>
    <name>A0ABR1VAC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ecp2 effector protein-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664019.1">
        <property type="nucleotide sequence ID" value="XM_066818327.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051387"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029226">
        <property type="entry name" value="Ecp2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14856">
        <property type="entry name" value="Hce2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046893770" description="Ecp2 effector protein-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Ecp2 effector protein-like" evidence="2">
        <location>
            <begin position="58"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="174" mass="18075" checksum="21D8DCF55A6A7C6F" modified="2025-10-08" version="1">MVRINTISIALLGLGLASAELTKVVVSPDLTARGSSINELRGQQTCKKCNKKGMTNFCDGSTFEKGDKKEWAAGGQAVKVGDCKKLMDQLSGTNQQSFVPGNCAFALKAGGAMSGSSGLALGSGDVFELVRDSIAKFAEGGKVTAHGKAFCRGQGADGRFADADVAWKVFNPYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VBK0</accession>
    <name>A0ABR1VBK0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664061.1">
        <property type="nucleotide sequence ID" value="XM_066818369.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051429"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012681">
        <property type="entry name" value="NCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00800">
        <property type="entry name" value="ncs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF4">
        <property type="entry name" value="ALLANTOIN PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8067308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="558" mass="61197" checksum="EE11536449658A94" modified="2025-10-08" version="1">MAFLSSLTESLRVPSQSRAVSNVWINDDIRPLPPHRRTWTRWAYVSFWAINQIAISNWQLGASLVALGLSVWQAVVALVLGKLGTAAVAVLNGYVGAEWHVGFPVVSRFVWGVYGQYFILVQRVVLSLVWFAVQSWTGGLCVQNILAAVFPSYQNMRNRFPESAHMDTKQFVGWVLFNILMIPILWFKPERLRFAILYMNIISAITLICIMIWCLSAAHGAGSLLSAPATVQGSSELGWGIVSATTAVIGSIAVGLTNQPDYSRFARRPGDQVLGQYSSIVLLGIIMPFFGCLASSASREIYGEAVWNPPDLVQKWLDTSYSPGARAAAFFAGFGLVVCQLAINTIDNAFSAGMDMAGLMPTYIDIRRGAYIGLVLSIAMCPWELLSSAGVFISVLSAYSVFLGPIVGIMVCEYWVLRKRKIKLSDLYHPGKGGLYYYWNVSTGVNLRAFSSWVIGFSYLIPGFVHNINPAIEVPEACTNLYSLAFPLGFAVSFLVHWGINKIIPPPGLAETDDVDYYSTFTFDEAARLGITPGDVLVGEERATGDIEKDLAVKADTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHT4</accession>
    <name>A0ABR1VHT4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664604.1">
        <property type="nucleotide sequence ID" value="XM_066815314.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048374"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047053985" evidence="1">
        <location>
            <begin position="18"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="260" mass="25475" checksum="362A2CB75189582F" modified="2025-10-08" version="1">MMLKISPFLLLAALTAANPVPGGGGEGGGHGGGWGGGGYGNGHGGGGGGGGGGGYGTQTKDGTCYPVTTTISETSTSTCTEYVTSSCVPVVTTETVPVPTTVVSTTTAEGSGTTIYSTVVQPTTVGGSTVVVPTTVYSGTTEYKETTIYITTATPVGTTVTEYDTVTTEIPGTPVTVATTVYSTIVSPGVGSTVTEYSTAYVTDTTTLPGGVSTVTTTLYSVSPGPGTTVTLPGTVVTETSVVATTVPGVGYTTTLPGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIC9</accession>
    <name>A0ABR1VIC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Helicase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664782.1">
        <property type="nucleotide sequence ID" value="XM_066815492.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048552"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345:SF2">
        <property type="entry name" value="HELICASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="822"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="880"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="912"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1002" mass="110054" checksum="4FC330B6664262C0" modified="2025-10-08" version="1">MATTTTVTSRTRSHTTSNSSPPVSAAAVRSPRSPIDPNKPLPSPPPPGTVDKADGQRAVPKVLKLKRIMATLSDVEIEKLFSGAPQYFARSQGLGTGAPHLVKHPSVAFPWDEELTIRDLSDHTQIEHDAWGNVTASPRIIHRDPWSCKSPTGKKRPHFSSKCSERPNMLSMQGLEKGSLGYQAALELAVADALQDEQYGFDSLGAKSHIVVDRRQQLVNSKDGLRGLDEAGIMELLIGCEQRYQSDRKDKTMRPTELHNELFSKILHPPSRLVDPSDPCSLAGQIYALVKILAVANAWIDFSRVEWRIRLGQILWGIPLDDELEDGSSINEGVDDQDRTEERYWLLIQLLLACELLIRLDIITDGDEFGAANLRMAEIHRFEKEANASHLTRGASTPKGWLTSLTNKMSLKHDHIGSHYVGSHYVDSSQRHPEYLYAIKGRYTERQVEGLVQFARKLRWPDIETYVTGVSINAPAMARATPINTPLATSDTNRSSYFGGERKTGEIQRKPSRRRKVEAALHPAGWLSKSYCSGLILPGEALSHFLMSTLLENDQDAMSKLGPMSNLCGGFIYRGKSFWSTACIVGRVLAAGRGAAECMGWISTDVTPENMSDRWLNINVEDIPDDVARTGRKARLWGKTIVERESDVLGDADPSNVLPADFIIPLENNYAEPPPSNIRIELRSLDLLAPVDSAHSTPTTERDMTPFSDSSTVSAIHTYPATTSFTMTHDSLEQGQDHDFSLAKDVYFVTAHPCVPSSRVKLLKSPSSPTIQQVDVDGHDWNSKAPSSAYITGHPLHKFYSYTSIHLTELLNKSNATLEDLVGANPIDPSPRRRASSTPRPSRVLVIDCITGFAPPTSPEMASLSRVSSISADFGLEPLSGSTPSLRLQNPPRGKNGGGGDSATSERLPLNTTATSVSSASSSSFGGRRASRIDPPPTPGAESKMRIPSRRRQFGSDLEVMVRALCAERGWNAIVSRRRRGCLACAIREAGALGWRVVIRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJD4</accession>
    <name>A0ABR1VJD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Isochorismatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011554</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665159.1">
        <property type="nucleotide sequence ID" value="XM_066815869.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048929"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF1">
        <property type="entry name" value="ISOCHORISMATASE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="4">
        <location>
            <begin position="9"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8071351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="235" mass="25117" checksum="85BF9E3AB2038E82" modified="2025-10-08" version="1">MKSALRAKTALILIDVQNGFLHPSYWGTERSTPQCEANIAQLLAQARAHNAKARESSSPSDEGGDDGTVLICHVHHHSITPSSMLHPDQTVEVDGVPRRAVDAQPFAAPLAGETVWTKDVNSAFVGTGLEAYLRSHRVRQLVVCGLTTDHCVSTSTRMAGNLRIVDEVDEDQSEKKKFTVVKSEGDIVLVGDACATYAKGGFEAETVHRVSLASLDGEFVHVAGTADVVGTVFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJJ4</accession>
    <name>A0ABR1VJJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_011614</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFB7 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665219.1">
        <property type="nucleotide sequence ID" value="XM_066815929.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048989"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008698">
        <property type="entry name" value="NDUB7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900">
        <property type="entry name" value="NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05676">
        <property type="entry name" value="NDUF_B7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8071411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="86" mass="10088" checksum="0C611FB6103B66F0" modified="2025-10-08" version="1">MAGSSAESLPKATREEMREAKLPIQYRDSCANLLIPLNRCRQGTYYLPWKCGDERHSYEKCQYEEFKKRVVKMNELREAKEGARSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKM4</accession>
    <name>A0ABR1VKM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BZIP transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011054</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664659.1">
        <property type="nucleotide sequence ID" value="XM_066815369.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048429"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013910">
        <property type="entry name" value="TF_PAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF8">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08601">
        <property type="entry name" value="PAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="4">
        <location>
            <begin position="126"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="107"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8070851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="312" mass="34217" checksum="346FD99B20FC8D84" modified="2025-10-08" version="1">MNFSHPFYGQNQPSYQFIGIPPLTPSHSNSAASDEFNNQSPPETFDGFQNPDQFQQNFDQYAQFNQQQAQSFPPGPPTPPTTHSLHGQGSSNAANPNKALQQADILPLTKSDPGNNGSNSDDEDMTPAQSRRKAQNRAAQRAFRERKERHVKDLEAKLASLEATQHLTATENEKLKRDLQKMSTENEILRATSSVQGPNGSMSPAAAVTTTTGPMHYNPTDFYSDLLANHTNKTPSHRVVESEAGERLLAAGATWDFIISHELFKRGLVDVGDVSERLKSQAKCDGQGPVFEERAIIKAINESVASGSDELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTB0</accession>
    <name>A0ABR1VTB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Initiation-specific alpha-1-6-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009162</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665439.1">
        <property type="nucleotide sequence ID" value="XM_066813477.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046537"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039367">
        <property type="entry name" value="Och1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834:SF1">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045677945" evidence="3">
        <location>
            <begin position="30"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="375" mass="42216" checksum="20300940CFB50DC8" modified="2025-10-08" version="1">MLSFKRALIFAAFLLTAFFLLRRSHGTTASDDSIPDLPKNRPADAEKGASSHAKGGSAVAAGAAPQQDKHVPTQKPMIDTSKMSLYDKLAYQYPYDVETKFPAYIWQTWRYTPADEEFAFREQEASWSEQHPGFVHEVITDQVAVHLLRVLYAAVPEVLEAYAALPQPVLKADFFRYLILLARGGIYSDIDTFALKSALQWIPDAVPKESIGLVVGIEADPDRADWKEWYSRRIQFCQWTIQAKAGHPVLRDIVTRITQETLRRAKEGGPFITKDKSVVEFTGPAIWTDTVFDYLNDPRYFDMSTSQGNITYLNFTGIESPKKVGDVVVLPITSFSPGVQQMGAKEPDDPMAFVKHDFEGTWKPESERHIGEQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTC2</accession>
    <name>A0ABR1VTC2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665402.1">
        <property type="nucleotide sequence ID" value="XM_066813440.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046500"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="36529" checksum="EC0C00D0F74BA2BF" modified="2025-10-08" version="1">MAKSKSRLTKSQRSEASRNKHSPKIKAAPPCAARDSVLTTPELLEAILTFVSIRRLLVAGQRVCRLWKDVINRSPQLQKHLHFQPEAEDENEGGRWEDSLPLAAPNPVLRHAFQDLFFPGHGKCSLRFGIPDLRRLPIADTKNGRWRHNAFVRTGASWRSMLVSQPPPQELVLVAGGRSQTGGMSNSTAIIRFRGPVRMGLLYDLVCHASLYDYQGAAVAWDVDPLQVLAWWMGRLPTVGWGPYPESAPPSYNRNIVIMGRYPKVFEQGQQQPNHPSQEPRAFLRRKMKKQMRDDGTKWMVLCEEYDAEVMERLIEEAEGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTZ7</accession>
    <name>A0ABR1VTZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GPI transamidase component-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009387</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665664.1">
        <property type="nucleotide sequence ID" value="XM_066813702.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046762"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009600">
        <property type="entry name" value="PIG-U"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS CLASS U PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06728">
        <property type="entry name" value="PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8074724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="387" mass="43061" checksum="936A3AF772317783" modified="2025-10-08" version="1">MPKDKMSFQATAGTAGLFVVAAALLQEGLFLYNHNVSPYDGGVYHQAPLLLPLFSLLPDPSTYPIFTYILYTLVDLLSANALYKIAESGEGEKRWSGYVVAALFLFNPFTIATCIGRPTSVFTTCVILHAVAKALSGNIFTSMLSLSFAAYLSMYPLLLLPPMVILAYDRTYNPKAPKSLAQLAGMCTLAVGVSLSLLFLSSYALTGSWEFLSSTYGIQLTLTDLTPNAGLWWYFFTEMFDSFRSFFLGVFWLHLSSYTPALTIRLRQQPLAVITLLLGIFAIFKPYPSIADTSLFLSLVPCFRHVFPLLRYSFVTASVVLYGTFLGPAFYHLWIYAGSGNANFFYAITLVWSLGLSLLVSDLAFAVLRDEWEVERPEMRGKEIRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU95</accession>
    <name>A0ABR1VU95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665332.1">
        <property type="nucleotide sequence ID" value="XM_066813370.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046430"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF92">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="38600" checksum="B7893EF15A8AADEE" modified="2025-10-08" version="1">MVYHDIDIPLPAFIAIDWTGMTLALLPILLRFWLRHKENKRQPWTRNVSDALVVLSWLSGVVLISINAWKNMLRYRYVHDPHPERLYYMVPKPQSAHLLYFALLAFFAGVLLIDGGSASAVRGCGWIRAVLAGCTVFTAATFCLHIALLTNWCHPVSSNWDIEGHLCSAVHDINSVTISTVANIATDLAILSLPLIALFTKSRERRRVLATAPQPLQEQPAAVIGRPEMTGVAFVVAMSALSITAALARFVTLKLVQDVPRANITHTIDVWALVEIVASLMAVSLPTLRVFVRRRRGRRQGPRKMMRSGGEGSSQVSIMSDRRRCASAMGSRGGDSNAERAGSVAGIPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUD8</accession>
    <name>A0ABR1VUD8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665803.1">
        <property type="nucleotide sequence ID" value="XM_066813841.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046901"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="267" mass="29893" checksum="8EE75040DE04ABAE" modified="2025-10-08" version="1">MAYRILHREWRSIRAMWYLMIFELLGTVAVLALFGIAQPDLFRTQLWRAGDQMGFNSSPNIVLYAYANYEPLPNVPFVWTENNYKKKLGNAKSATAKEPKAYPELRLTNFNVAISVISLFVLITKMIGVIMHLWYPLLALVFNIALVALYATSVYGQAGPDYADPTKPSAAAWYIAKPCSVVPNQSIQKSCTMAKGTFAATIIMLRGFYESDGEEENSPAAPKSNTHWEMHGVPPTPRTGGVAVPYTPRTMAFNTLERKLPLRSQYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUI0</accession>
    <name>A0ABR1VUI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665848.1">
        <property type="nucleotide sequence ID" value="XM_066813886.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046946"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="103"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="254" mass="28688" checksum="DA30ECE748AEA879" modified="2025-10-08" version="1">MTVTHEIPHNSPAGFRIREATQDDAEDLTRLWYSSFNPSHAFWDAATPDDTVTRRWWNDTWAVGFQAGPDVLRTFVVEDLAQGGRIVALARWNVPQDEGRQDIPLPDFPAEWDAEITEALWGGMPQNRREVMGQRPHWSEFVAPPFLYTGSSGIFSYARPLTTSSIEVLEFLGVDQGYQGKGLGFALVDWGCRQADKAGLETYLDATIKGLPFYKKCFGFEERKALVMPTRHDTYGNYELVASVRLPRTKPKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VV62</accession>
    <name>A0ABR1VV62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009798</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666075.1">
        <property type="nucleotide sequence ID" value="XM_066814113.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047173"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="29"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="387" mass="42411" checksum="B63CA8DC829F8E18" modified="2025-10-08" version="1">MAFLPPPVPKSLLGRHRLLAPSASVRVSPLTLGGMSLGDAWKMGMGECTKEMAFELLDTFYDLGGNFVDTANMYQGGQSEQWIGEWMQKTGRRPEMVVATKYTMNPMVGHMQLQHSNFGGTGTKSMYLSIHKSLKNLQTDYVDIFFVHAWDFATGIPELMRSLNVLVDQGKVLYLGISDAPAWVVVKANAYARQHGLRPFSIYQGRYSAQERDLEREVIPMCHDEGMAVHAFGTLGGGQFKSPDAEDTGSRQVPPHLRIGREASVAKFLDAVAKRHGVHITAVALAYAMQKTPYLFPVVGGRKVEQLKANVEALSLELSPEDVAEIEKGYDFDVGFPHSILNSNGTMVKGPQDVTLLAGMGHFDYVASPSAVKPHKGELTAAWKAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVN5</accession>
    <name>A0ABR1VVN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="5">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665827.1">
        <property type="nucleotide sequence ID" value="XM_066813865.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046925"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044674">
        <property type="entry name" value="EDEM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679:SF5">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8074887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="688" mass="76350" checksum="A2A8E80B2DA77C02" modified="2025-10-08" version="1">MPNPAPYGSQLDPNSLYTPLTDEDNSADAFLEAWHHAHAAIKRHLYSDVHHPHYINAHISTGSPQAYWIDSLGAYYSGLLALAGELDEAIGTHLLYTALWTRYSALPERWSVRDGHVEGGLGWWPGRPEFIESTYHIYRATKDPWYLYSGEMVLKDVRRRCWTKCGWSGLQDVRTGEKSDRMESFFLGETAKYLYLLFDSDHPLNKLDAPYVFTTEGHPLIIPRKAGQPKARKKAVEKGVLPYYDEKYTNSCPVPPKLPPLSGSATAARPDFYHAASLIRLHHIPNIHAISNQEMSTVAREKSVAYAMKPKSNHTIFPWTLPPTMLPLNGMCAAMRQQHTSVIEFPTNTQHSVGNTFSLMFGGHNLVRMGSEGIAISSLNGLKITLVLEEPPDYIERAWRVSSIGHLALGRDEKVFITRDVLAEMSDPLFHRIRDSVSVDILLQTEIPPPPMETPTNFTASDSKAQGEVQSNIEMAGSPGSSNIFSSFLQQITSVLREPASTFAPEPAQQPEYEYTELAAILPAGLGAAPLPDVREAPNPVTGVNIESLTWGHVYFADQACRAKLPDAAAKAHQVIVMRRGGCSFSEKLSNIPSFAPNRNALQLVIIVSEDKEDESEGNSWGFNFIRPLLDELQKTPAGILRHNPIAMVMVGGGDKTYRALEQAKSLGLRRRYHVESQGLAIGNLVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVY0</accession>
    <name>A0ABR1VVY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665932.1">
        <property type="nucleotide sequence ID" value="XM_066813970.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047030"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13854">
        <property type="entry name" value="CuRO_1_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF145">
        <property type="entry name" value="LCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="76"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="187" mass="20796" checksum="25FCA407433CAB01" modified="2025-10-08" version="1">MGLFSLCSGLLGSITPEQQNLKSLWGTLLLPTLPMWLMGKDGSYGVTPWGNRTAEGTNAYIDYPTTGVTRHYEFNITRDVIAPDGYQKSVLLVNGQFPGPLIEANWGDYIEVKVNNHITDIEEGTSIHFHGFLQSQTPWMDGTPGVTQCPIAPGKSFTYKIQATLYGTTWYHAHYSAQYAGGFWVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW48</accession>
    <name>A0ABR1VW48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666392.1">
        <property type="nucleotide sequence ID" value="XM_066814430.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047490"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="74" mass="8518" checksum="0F21C3CC317BDD1F" modified="2025-10-08" version="1">MFETMKSCCMIQRGFALHGTRRCRTETCQEEFVKDPSNCAHTPWGFSDLEWQAEDLRDLKGITYDPKLDAARSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX50</accession>
    <name>A0ABR1VX50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrogen permease regulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NPR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666775.1">
        <property type="nucleotide sequence ID" value="XM_066814813.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047873"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009348">
        <property type="entry name" value="NPR2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991:SF10">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991">
        <property type="entry name" value="NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06218">
        <property type="entry name" value="NPR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="22877" checksum="8FCCE5B721138316" modified="2025-10-08" version="1">MEWIKLHQDAGLPVLSLVDVRRLVQFGVIKGLLYRVHKYVVSKQYLALLASGQAHPRQHHSHRRGQRQNQQTKSQSQQDQQKGRQGQRPQNLSRHSSRRRLHTWDIHDANNSDEDDDDENDSNDETEEEERERARLKSHGKEEEDLLASDEPLQRYTDGCHSFDQIITEQNMADAEIMEKLKGFRAPAGDLTVFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXF3</accession>
    <name>A0ABR1VXF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA mismatch repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_010530</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666807.1">
        <property type="nucleotide sequence ID" value="XM_066814845.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047905"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="9">
        <location>
            <begin position="1017"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR037677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8075867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1181" mass="132377" checksum="9CF849EDA5DAF071" modified="2025-10-08" version="1">MGEKSLPKTPSLTKKTSSMSSTGGKQRSILGFFSKPAQNAATAPSAKSSPPKEANSSLCLKESTTKKKAANITPVPSSDAIEPSSSQENHSEATPKQATPATAISKMALASSPSRRAKKQVSYAESDDEDEDVVVSRKPTRSRRTATRPVTRKTMKKTMTRRQRKPTTSQTIPTPPSKKRKRPQSKPQTARKRSQASSPPSRQEPEDDLEDEEPMEEMPSTSTAQQWKYDPDTVNPVQLRKTNTPDVQAAVARGQAHTREPEQRYSWLAKMSDINRNPVGHPDYDPSTVYVPPSAMAKFSPFEKQYWEIKQKLWDTVVFFKKGKFYELYENDATIGHQLFDLKLTDRVNMRMLLDIWTNQFIAKGYKVARVDQMESALGKEMRERDGGKAKKEDKIIRRELACILTGGTLVDGAMLQDDMATYCAAIKESTVDGHPAFGIAFVDAATGQFFVSEFDDDVDLTKFETFVAQTNPRELLLEKSHLSTKALRILKNATAPTTIWNYFKSGAEFWGADLTRRELDCNEYFKKDDDDNKEEWPATLVEAKDKDLLMSALGALVQYLRVLKIERNLLSQGNFSWYNPIHKNGTLILDGQTLINLEIFNNSSNGSSDGTLFNLLNRCITPFGKRLFRQWICHPLCNIDKINERLDAVDMLNSNTEIREQFSSEMTKMPDLERLISRIHAGACRPEDFVRVLDGFEQIEYAMSLLAPSGSSDNTLVNRLIKSMPDLTEPLAFWKSAFNRKKAREEKILIPAEGIEEDFDANAATIAGLKKDLQRLLEKKKTELKAKNLKFTDVGKEVYQIEVPKSVKVPKDWNQMSATNAVKRYYFKELTNLVRELQEAEETHSQLLKEVATRLFQKFDVDNDTWLQAIRIVSQLDCLVSLAKSSASLGEPSCRPTFVDEERSVVEFEELRHPCMLNTVDDFIPNDINLGGDSAKINLLTGANAAGKSTILRMSCIAVILAQIGHHIPATRARLTPCDRIMSRLGANDNIFAAQSTFFVELSETKKILSEATPRSLVILDELGRGTSSYDGVAVAQAVLHHVASHIGCVGFFATHYHSLATEFESHPEIRAKRMQIDVDEAARLITFLYKLEDGVAEGSFGMHCAAMCGIKESVIERAEEAAREWEHTSRLKESLEKARQGCYIPLGMLSDVAAVLDQAKTPDLNDRSLDVLMRAIEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY66</accession>
    <name>A0ABR1VY66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666727.1">
        <property type="nucleotide sequence ID" value="XM_066814765.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047825"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="112" mass="12532" checksum="AA0AC89256FF046A" modified="2025-10-08" version="1">MYPRRMTISKAYLTHTAPEDRALQLDPTSTSHTNSYEVETKVALVQHRPSNDQQAIFAEECVYLATVDNFQGEEAKVALGMKQRGERDVGSLSTPNRINVPLFKSEARSCTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZ03</accession>
    <name>A0ABR1VZ03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666094.1">
        <property type="nucleotide sequence ID" value="XM_066814132.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047192"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="748" mass="81446" checksum="9C2C8E72C0F628ED" modified="2025-10-08" version="1">MVKRSIPTREPSSPPFDFALDVLGQGKLPRRIFRVPADQEKLLREPTSWAEDLFRRPQGLANVTVEVLDNLSDFHSRQLQEPQQQSSAIASQSPSVLHRETAAVPTSPSGTRSNLAHGEDGDSSPGTPISGWNSSPPPVPRSEPPEEESDDDSFTSQLPAPPAAMMQPVSSPDGPNSRRDQSSLEQPFETQLPARPPLQVGPGISNLQKRPVFDDFPSSSPAMDEELEIVQPAAYDRDMMPPPPHKAVEPNPTPPSAQQVQVPSTFPEPQSSKSASEPPKVKAARKHRLMPRVNVRHQWQIPPKTLIRETQVSLGSKQLHVPPQSPKHKPPTPLLPPRIAQSPLSSSHGHPSSPSDRPLTFSPPPPVAAPLPAPHVQLSVPNSTVPVPDPSGDDSGPRPDEPVAQPVEQNSMHDQEDTNLEERLADLEEQLKQAKLNIAYYKAQVRSGHPSSSVHAAGCSKPAEIHNQTSVAEQDAMVVDEVPQQREMVERNAEHTPFDQYTNAYPAYKNHGNIWEFVKACVYIQQLQRKKPSQHIKAEGARSHLRVAGSRRGPLPKSLPPAEPTLALPPTPAIGTARLLDQVLAQPEEEVVDLANGADSTVPAGHPQGHQELRGSQSDPLDGTITEARKPKPPAGSLRHSTSEIFSRKRPAGDEVIAASPKRKFSRTLSSRQSERSTPSATLQPSSTCGGLPRSSAPWLGPRKHANDPKKRARSWEKFLAKKMRRDQESIVNSSAPPGGTPTSGQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7L0</accession>
    <name>A0ABR1W7L0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666946.1">
        <property type="nucleotide sequence ID" value="XM_066811604.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044664"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF6">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047053989" evidence="1">
        <location>
            <begin position="28"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="272" mass="29564" checksum="04B0F63CF3EB8E27" modified="2025-10-08" version="1">MALFNFQTLSLKNVLLLAAAIAPVVNAAGLVRRDPPNALPGCATDADKRFQPVMDFDKDGCYNSPAVDANGNIATGLKCGGDKNGHCRDKSDLDNNNVYSRARCNNGWCAHMYAYYFEKDQSVHGSCGVGHKHDWEHVTVWAREGADSASYVAVSQHKGWEVKDAADVRFDGSHPKIVYQQDGGLTHDFRFANEGDDKVENHNGQWFTGALLSWNGLSDTVRTALVNGDYGAAYLNLKDSGFSNKLKDAKGGKDIPLDVYSDNANSPGTPQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8R2</accession>
    <name>A0ABR1W8R2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Altered inheritance of mitochondria protein 41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AIM41</name>
        <name evidence="3" type="ORF">PG997_007686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667343.1">
        <property type="nucleotide sequence ID" value="XM_066812001.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045061"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="entry name" value="Uncharacterised protein YqeY/AIM41 PF09424, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="209" mass="22472" checksum="1D135B5126599130" modified="2025-10-08" version="1">MAFQAPKRLPLGLVRAARFTNATTWPAARSLLSIPNTTPLCRRQYSSDPPPPPLLQKLKTDLKTAMRAKDAARLGVLRSILAATLNASKTASPIVTDAQLVALLRKTARASRDAAAEFQEAGRADLVEKEQAQIDILDEYAAGSGVQEVGADELRTIVAGVVTAMTSEGGEATGGKAQMGNVMKKLLSPGGPWRARTWRSPSWRRLSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8R3</accession>
    <name>A0ABR1W8R3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007689</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667346.1">
        <property type="nucleotide sequence ID" value="XM_066812004.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045064"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="180"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="520"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="68"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8079871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="916" mass="104447" checksum="89B98B9BE84EF246" modified="2025-10-08" version="1">MSSRVSNYADRRSNGNSNDNANPTSSRPRMASGNHSFKAEHRESRSGSFTSTAHKRSASGNPRPASRSAEERRTERATITTREKLMSRAKSPERRSRDYGPSERWKTKEPSRHRATESKREVPLEAPPKIWEPVASLSKPSTAPLARRITVPPLASDMPMALQPQALHQLSLEAQEAVIIEDLLFVFMGYEGQYIRFSYAYNPSEERDQLTGPTYKISSGLDPSLEDLTQSMLKMATHYTALGHFVDVQSREEFGAVNHALCAAIRKYLHEYLIMVAQLETQFLTNDSFTLHVLNIHTLPTSQIMAQLYFLAREFLKKNGMLDDESEEESDPEDIDQILENLKKGGDIIPGNVTGRKVCKGGVVLAMITKRLETMSGDPAARSLLTSLLRDASRPYMAMLNEWLHHGGINDPHGEFLIKEQKSITREELDKDYTDDYWERRYTLQREQDIPLQLVGLRDKVLLAGKYLNVVRECGGVDISKVAQDVPVTFDDSRFLENVNNAYAYANESLMKLLLTTHALPARLRSLKHYFFLDPSDYFTYFLELGSSELRKPVKSVNTVKLQSLLDIVLRQPGTIVSLDPFKEDVYVDMNEISLIKMLQRVVNITGMEQGEVLQPTSAASLEAEKNANGFTSLELNYSVPFPVSLVISRKTIWRYQALFRYLLSLRHLESQLCTTWQTHNNAIVWCHRSSARRIEIWKRRVWTLRARMIVFVQQLLYFCTLEVIEPNWQALMSRLKMKDGSLEGTGKPDRTVDELMQDHVDFLDTCLKGCMLTNSRLIRIHSKLMQTCTLFAAYSNWLSRELEKADPDLVGNIKPPNMSDEQWRRFQALKPQKSHNDSMASNKSMLDEEARVSNLFEILKKYETNFSRHLQILLDALNHYAATETVVLLSLCARLATANQGTEYSGLRHDEDIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAM7</accession>
    <name>A0ABR1WAM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667041.1">
        <property type="nucleotide sequence ID" value="XM_066811699.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044759"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051616">
        <property type="entry name" value="Cul2-RING_E3_ligase_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46224">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46224:SF64">
        <property type="entry name" value="IQ MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="409"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="510"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="695"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="900" mass="97845" checksum="9D58856A152E8A2F" modified="2025-10-08" version="1">MAPVKSEAVLSHCHKATVLGNKIAIHMLDFLSTVKTHPHGFVELANEFLDLCKIMWALEAGLTECTRTNQQFPAEMIKEMDNKFKSTYTDFQHLDQWVGRFLEYEKRGTVGKIQRGWRNMFADNDVGKMRESIGKAIESLRMSSLVFQWSLGDSNIDDSFGMGYTGLAAALERLQRGRSVTGITKLKTLEPHLTEVEETSPISSVFPLPPVLEIGRGSSTNLSPFDVIRDDNSYQQQLSLSNRAPSASHHSPSVSHRAPSVAKSVSNHTSPSVSGRDRVFSQAESFDGRGTQDNVGLSGMTEGDTTAGDYESSDSGAIKVTRLTADPVKMPRWSPRNSTGSSTPALKLALVSAIQDRNNKLVEQLLDRGVPPDTGSESHALKEAIMRHDLESVRLLLVFGADPNSADRGGITPLFAAVEESFIDGADLLLKYGADANLAAGAVLETPFGLSVAEDKFSFAKLLLIYGGDPNHVMSDGETILIKTINKVRPIKFIKLMLAYGSDANAKNREGKTPLFEAITASRADIVGELLDAGANPNLPGPKHMLWPAIHHTPCLRLLLARGADPKKTPGIMELAASINNIESVRCLLKAGVDPNEKKDGVYTPLCSSIRDNRADIFHLLLANGAGPNVPASEYPAFKCVTHYRTQYLAPLVKAGADLNTPKGILETAVQSNNTEALEWLLNAGVSPNDKVPKSGATALTTAIRQNRPELVDLLLSRGADPNVRGQDWPVCMAVKQPQILKRLLPALAEPRAFKGCNGNGRGVSVEDRNGGVFSPLTTAIRERRKDIVSFLLDEAHADVNAPGEHLPIVKALRRYEDGDTEIVEMLLAAGADPNKIYRGHSAFIQAVENGDAHVLQLLVDRCGVDLHAKDDNDMTILEIARSRGWEEGSVILMNGKQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBB7</accession>
    <name>A0ABR1WBB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007261</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666918.1">
        <property type="nucleotide sequence ID" value="XM_066811576.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044636"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF23">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8079443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="436" mass="46289" checksum="95DE253A8216896E" modified="2025-10-08" version="1">MTKTATAAATDDRIELVPVTNNVISQVSHPPHIENDSEAAVAGCGPDPNARPAAFRSLAHEILFVLTATMSIAMPSFLQGSILIVVAASSLTSGSFLLFFGKVADLLGRRSILLTSLFLFALIALATGFARNAAALIVLNAVMALTSASIIPSAQGILGSIYERPSRRKNYAFACFSSGNHLGFAVSAVFPGVASQVAGWPASFWLLAVMYAAVAIIACFTVPPDDTEKLPFNRECSDVFIPILDLSGTELTDLKQNTSVGPDSPQGWRTPYIIVFLVLGPVLLLAGRLLHIVSNKLLMGIGAAGFTISFLLVAVQRSGASYWAFTFPAFVIVVFGTDFEFNVVNMYVVSSLPKSQQSIASSVFQTTIKLATVLGLGICAALFASVAERPARSGYYAGDPFEPYAALFWFAAAVSFVSLLIVPLLHIKTQGHIKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBZ5</accession>
    <name>A0ABR1WBZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS quinate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007849</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667506.1">
        <property type="nucleotide sequence ID" value="XM_066812164.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045224"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF8">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="31"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="533" mass="57783" checksum="8FD855ABCF4E63BA" modified="2025-10-08" version="1">MATGPKKPVNIFKLKNLGEPKNVFNWRLWFAVISFGLLGAARGVDEGLIAGAFGSADFQDTINLSSYSLVEQTNIKGNVASMVQLGSIGGALIAFVICDRIGRIWATRQLCSLWILGIAIFMRSNGSLGAIYAGRLVAGLGVGQTAVVGPIYIAEITPASIRGLCTCIFTGFVYLGIVLAYLANYGAQLAPTSIHIIFATIILAMTIFQYESPRYLVKIGKPEEALLNMSRLRNLDTTDPYLVQEMKSIEASHQEEVAETRNLGFLGVLKEMFCVSSNLYRVYLATMAQLMAQWSGAGSITVYATDLFMLLGFNGKNESLLIAVIFGVVKLLSAVCCALFLVDVIGRKRSLMAGITLQAIAMIYVAGFLTAVPQLGVAVEFVLPKAMVPASYGAIAMIFLSGIGWALGWNSMQYLLTAELFPLRIRAVSTSLAMTIHFANSYGNSRTLPHMLLSTDHGGLGPAGTFWFFAAVTIVGGVWVWISIPETAGRSLESMNKLFELPWYKIGRYGNADADRMVKAHIPVDEKLQKVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEC8</accession>
    <name>A0ABR1WEC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proline--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_008342</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667999.1">
        <property type="nucleotide sequence ID" value="XM_066812657.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045717"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00862">
        <property type="entry name" value="ProRS_anticodon_zinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382:SF2">
        <property type="entry name" value="BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PROLYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="11">
        <location>
            <begin position="92"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8080524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="555" mass="62326" checksum="21CEE7B9BC3EB1D6" modified="2025-10-08" version="1">MADASAPEQSKSAMKKAEKEAKKAAEKAAKAAKQASLPVVGGKKTDDIIGITVSKQDNFSQWYQEVVLKAEMIEYYNEISGFFIMRPATMYIWNVIRKWFTAEIEALGVDETNFPMFLSAKSLEKEKDHVEGFAPELAWVTKAGDKNLEVPVAVRPTSEAVMYPYYAKWIRSHRDLPFRLNQWNSVVRWEAKQTTPFLRAREFLWQEGHTAHLTEKLAGEEVLQILELYARIYEEILAVPVVRGKKTENEKFAGGYYTTTVEGYIPSNGRGIQGATSHCLGQNFSKMFDITVEDPAEKGKHINVWQNSWGLSTRVIGVMVMIHGDDKGLVLPPRISKIQVIIVPVGITKSVTEEVKASHAAQLQDIKKTLLSAGVRTDEDQREGYTPAWKFNDWELKGVPLRIEFGPKDAAKEVVSYARRDTGEKGTIPIAEIGTKVPELLETIQKDLYTKAKASFDEHRVVVEDWEKVTPALDAKNVVLIPFCQEPKCEDKIKDLTTTKHDESPDASVPQAPSMGMKSLCIPFEQPKQLAEGTKCLNPECQATAQSYVMFGRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WG11</accession>
    <name>A0ABR1WG11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008927</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668584.1">
        <property type="nucleotide sequence ID" value="XM_066813242.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046302"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8081109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="453" mass="50881" checksum="F893BECB92188C51" modified="2025-10-08" version="1">MTDQTIPITRPFNLVPESPWAQHFYPSHDPLFRQLGDGLHHSGLAPARPYVPWDQLGQIPQNEEPLPSTQNLDFLFYAERYQRIKRSGMMSWRLPAMIADLYDLSKRNDIEMDPNLIQVNEDGWLDFLKRSKWFDRRVDALSSIPNPHPDLYNHPNNWWTVDNPAIWRIVRIALEMVNRVLNTIIESRHPWLDTVLFSQLQKWSDIDPTMAAHCAENQNDSPGVMTERPASARATAAEMRAALNDALRFCVLSFVDEASVTQGEGIYGYSAFGFTYEAAGYINKMVQGDVSAVAPALQTTRNLKNLPLYVKKPQDTAGNPVLTGFEDFEGCEEFMPIEDLVAQAVSQTPGPDDSVMDAAAIALAALGPISGDEFKMDPVDTLLCTVHVAPLRCLLNTESKPFERYNALMSMAVTVSEPPNMRRILYAHAMVAQILHELSVGFANISGLCLLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL31</accession>
    <name>A0ABR1WL31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005507</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668745.1">
        <property type="nucleotide sequence ID" value="XM_066809822.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042882"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475:SF3">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G14290)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="28"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="550" mass="60221" checksum="BE5D38F074BDA611" modified="2025-10-08" version="1">MSSSSQPQHHNEVTDPAADEGDMTPTLKKREVAASFLFRNVLDDPRKVQVALFRRSGAVRTYQHKLAPISGSVEKDDANALATAFREIKEETTLGPESIDLLREGKPYSFVDESIGRQWTIHPFAFILKSSAEEGDGQGGEGSGIVIDWEHEGWDYEGWDWYDPLLFGGVPRLLDSLRRVWPAIDLGARAGSTLTVGLSRLQTDHERGARQLAALAVSYLTGVFVEGNCSMDDGWWARVRMAAWHLWKNGRESMGAAIVSALVTVLSRIENEALKPGGTVFERSNRVSAVMDEWREQRDSIISKVQASFVDLVRDRVLSEGPKKKKKKILKVLTLSSSSTISSCLLQAATALDVTLDLRILESRPLCEGVTMASKLLSDAEHEKRVNITLYSDASAALASEDVDMVLLGADRISSAGDVSNKTGSLPAVLSAKHVSPSSRVVVLSEVDKIAGPGNASDHAAEENDAIELTRGWEGTVKGADDVLAASYSTEAARSGDDSPRVKVKNIYFEWVPARLIDAYVTDEGVWSSDDIRKRSDWVGTEIDRFFGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL67</accession>
    <name>A0ABR1WL67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Proteasome activator subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005513</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668751.1">
        <property type="nucleotide sequence ID" value="XM_066809828.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042888"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032430">
        <property type="entry name" value="Blm10_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032372">
        <property type="entry name" value="Blm10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055455">
        <property type="entry name" value="HEAT_PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035309">
        <property type="entry name" value="PSME4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170:SF3">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16547">
        <property type="entry name" value="BLM10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23096">
        <property type="entry name" value="HEAT_PSME4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16507">
        <property type="entry name" value="HEAT_PSME4_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome activator Blm10 N-terminal" evidence="3">
        <location>
            <begin position="28"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator Blm10 middle HEAT repeats region" evidence="2">
        <location>
            <begin position="383"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4-like HEAT repeat-like" evidence="4">
        <location>
            <begin position="1365"/>
            <end position="1571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="921"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="930"/>
            <end position="954"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1912" mass="217304" checksum="D10799661E297893" modified="2025-10-08" version="1">MEDHLDLSNPGALSGAAQFLSAFGSSGEPISRATSPGLPSTPDADSHDTSKRHRPRTFSYFQLLPYPVEEEAQRDAALQGILKQLYISIKAEDFSPGALHWTRQLSGWLSLKFDMPRDLRAKLARLYFHLSLAPGLDGAAADRFSRMVSTLARRKHLLKPGEDLMLDWRPLWKEIRALVLPGEAPAHHSARRRGLKHLWKLCLQSYTYFDPSERRAMLDEILPFFSTSDLQDAYIVVGTLNILMPTTPAPPTAPQSQPSDFVPTFFHLWSLMTRSKVFDITFLDMFSRMARDYLAYRHVPFTEYGIFTREQSDLIFTAILRLTEIPVGQANSPYTSLDYSSGMGIFLEKDKKKHPISYTIARWVVSSLSPQCLEKDGSILNSLEGLLESIDTFFHPSNQGSWTTMLAQMTFYLTEMFVSRWNKEQGNEQDTPVDRRLNEELKHRFVKSLREVTFMGLFGKSTKVTNMYFGALQNLTYLEPDLMLPGALQRFYPSLQGLVEVHRTTSSLCGLQMIANIMSRQKGFRCHITALLALALPGIDANDLNKTQYTLNFIQSVAYSIPFVDLTKENSSVHDTTLAMQWVQGEMERMEREGQEVQIDYKNELSDEDEANIVRSSTAGFGEFILALLGKVFTLLENLPDSSQLRSGSPEDNIINTLPAALTPLFASLSPELFDMALEKLSTFVSTHVVHQARDAMAWICNALCKVNPEKTLKVFLPMLIVNIRNEIDYNGAASDRSSGTEVLPRDRALVWHVSILSMCVVHVGAEVLKYKTELFDIAKYMQEKCRGLPTIHISNYIHHLLLNLTATYPIDNALFEPDVIKRGLDVQDWGQSTAPADLTIRWHRPLPAELEFAVELFQSQAQGAMERLEVFMGSDAPVSRKGKNKEWSDEVSRQLTQLRLVISGIAILFDPKWAFSDANGVNGRHADNDGDEMMGDRDDEEENPLAEAGEDDETRPQFKYQSGYLLTPENPLYSRIHQIRDEIGRLLSRTHAFLNNQQEDDVPCFTALYSTYRTWITDVGFERSAHPLERLQRLYKADIGPFKISGLRKAYPRPLLIKRADAYQLQRVKHNASVRRKSEIDRQLLLDLAESCTSQYADVRRIAQGAQDASLKVLIGGRPLVIPVILERFRKAMDAMDHDRIKGAMYTLLFTSLLKTLIRDWRYAPDLLRLYIRTAGVDKTSIQNLGATALYPMIEFGKRFELMVLLDDEIVSQIKPAEDCSGVIASRHDFVVERRRKVEEKKIALGLELIELSKESHWKTASRCVIFTTNLCVRFDSIAPPQFIELVTRGTNDPHPGLRSSYLTAFSNVFAAIDQRAVYNHSYRDYLEEKEKDVNKVVVPVEKGDAEFTRNFLDSFADLDRAEYFVDSDYAGWLAWGKKFNAFRTKPKRFDEYDDVEVAARQQIGKLVTRDWLKQFFDYLKQEPRDSSSDRFRSPVVILLMHVFDLMNYGQTELTFEDVTTLTAEVYGDGTDKHQHRATSEILGAMLAGSADDPVEMKDQSWGFAQPMLLKIFADSLTPENLSYWMTCLHFIIDTKDPRRAPELVKTLSSFRLDMSSNAAFKEASKVGLLEFLINDCGWHFRHEKPVLADFLAHIDHPYKSVREAIGRVIATIYRTRYHESFENVSALLDQNKAVSSSGIGIRPYQPDEEFSATIKDVFSRLEKWRHERTPGQQTPSSYTSGSKTVLTWLDNTLSSQECTQLTSFFPDPFIDQLLHMMDVKEDPELMRLAYHVYRHLPNIPFRTGEDGPFIAALIRLGKGATSWHQRLPGVLFDAVGDMLADPQLEVRTVAGATLAGMIRCSPAMIRNPVIESLKSRFERALAQNPMPKKKTPGTDTPVNATQQVVRRHAAVLGLGSLIEAFPTRRRRRRDQEHSVGVQEDETGQLGVDQKYFTSEQLEDLEGVLWKSYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLL8</accession>
    <name>A0ABR1WLL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aquaporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_005716</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668954.1">
        <property type="nucleotide sequence ID" value="XM_066810031.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043091"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF283">
        <property type="entry name" value="AQUAPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="46"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="494"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="547"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8084445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="586" mass="64120" checksum="480248E13EF31638" modified="2025-10-08" version="1">MPASLSDHSTRTSNAVERTITERSTIHPTNSIDEHDNFFEYQQGQDARAHRFGPGSRTRSHNNNNGHESDFDQRDSGSYFEGATLNSNNAAAPGSPLPSQFASPSRRTMSFYEMQEQAKQAKKDAKLQAKKARRQSLMIQRASWRSGEMPYNYADMIGGNRHDYNPPTMGRPQPRDTMRDNRYSAGTWTMTGGGGNGSGRDTPDPFSMRLPLTMWMHSEAKNLFVAALGEWVGTTMFLFFAFAGTQVANAGSKTPAAATTTNATAGFDPVVMLYIAVSFGFSLMVNVWVFFRISGGLFNPAVTLALWAVRAVSAKRAIVLFLSQIVGSITASALVLALFPTRFNVRTTLSEGTSLPQGVFIEAFMTAQLVFTILMLAKEKHKSTFIAPVGIGLALFVAELVGVYYTGGSLNPARSLGPCIVTGQFDPEHWVYWVGPGIGALIAIAFYQFIKMLEYEMANPGQDGDDENDPTKNPNHELREKQREATMRILSSLGIDQQPPQPQGPGTQYSSSAARSAEEGTHYHPSPIISMDDSDHERRHNPGVALSTVQSMSDHVASPTTAIHHDIPSGRNSPHKHSDRSSRSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNK0</accession>
    <name>A0ABR1WNK0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC multidrug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_006350</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669588.1">
        <property type="nucleotide sequence ID" value="XM_066810665.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043725"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF345">
        <property type="entry name" value="ABC MULTIDRUG TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="498"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="533"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="897"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="939"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1018"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1043"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1117"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="287"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="611"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="903"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1219"/>
            <end position="1478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8085079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1482" mass="163796" checksum="DBFB82B489C86E13" modified="2025-10-08" version="1">MTKSSRIPNLDNDYTRISARPNVSGCRNDFDFTVKFELVMFSVVPSAIFVVLAFWRTLHLSRKPTIINEPALQLLKLGCITAYLGLQLALLVLVAARSFEVTALSISSTVLRFLAAIGLVPLSLLEHSRSARPSVLLNAYLFLSLLFDITQTRTFWLASGTRSEKANTALFTASVALKVIILLIEARRKRIFLNKWDEREHSPEETSGLYSLGVFFWLNRVFIDGYSKILQIDDLYPLDSGMRGKVLDERFARYADYSTMKGHKYGLLKMLCRTLLVELLLPVAPRLVLLGFLFCQPFFIERLLTYLSEPEGPNSSNFAYGFIGAAVLIYSGIAVSTALYWYFHYRTLLKARGILVSAVYRKTLEAQIGTSDSTAAITLMSTDIERINVCFRSVHDVWASFFETGLASYLLYLQLGPAFVAPIVVVICCILGISIISRYTGDAQSKWMAAIQRRVGLTSTVIANTKNLKLSGLTQPVANSIQQLRVDEIASGSRFRKILIASAFFAWTPGVLSPFVTFAFASQQLGATKIFTSLSYVILLADPFSIIFQSVPQIIAGLACLGRIQKYLECETRSDFRSLINANEAHETSSTEKAVAKHEKGPSLSGNSPAITINEGSYGWTPESMVLHSINAKFTSSALTIVCGPVGCGKTSLCKALLGEIPFHSGHMRLHTAYRRVGFCDQTPFLSNGTIRQNIIGFSDFDEKRYREVLSATMLDVDLETLPSGEMTNVGSNGITLSGGQKQRVSLARALYLQSDLLILDDIFSGLDADTEEQVFQRVFGPDGIARRRNSTVILMTHSVKHLPAADHIVALSIEGTVTEQGTFPELMANDGYIRGLGIKATGSEASSAKLDLAADPQGPAAELLRQTTAMSSIAPDMSKARQTGDRTVYTHYFRSIGWIVTAIIVFWAACFGFFQGFPNIWLTYWSADAAKGYEVRSWSYYISIYSVLQISRMLSLFMCAYFVLVTAVTKSGAKLHLDTLTTLMHAPLRFFTTTDNGQTTNLFSQDLNLIDMELPNALLNAVLGCFEVIAGAAVIMSSAPAIAVSYPFLALLLYFVQRFYLRTSRQMRFLDLEAKSPLYTHFRDTTHGIESIRAFDFTEEDHEKNRQLLDTSQRPAYLLVMVQQWLVMVMNFVVMVLCVILTSLAVKLRSNSGFTGASLVSLMTFGNQIAYTVVFYTQLETSIGAVSRLRAFNETVKPEDRDDEDLVPADNWPEKGEIELKGICASYNTEVDEDKDPDLALKNIDLTITPGEKIAICGRTGSGKSSLIAYLLKLLDPVPGKAAVARIDQTPLDRIDRPTLRRRIIAIPQEAVFLPDGSTFRANLDPFSVATEADCRSVLETVGLWASVEDRGGLEAGMSAGTFSQGQRQIFSLARAVLRRRIRARGLGLGQGAAEGEGGVLLLDEVSSSVDLETERAMQNIIRVEFQKYTVVAVSHRLDMVMDFDRVVVMSNGEIVEIGPPKVLAEDESTRFGELCRAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNK3</accession>
    <name>A0ABR1WNK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669619.1">
        <property type="nucleotide sequence ID" value="XM_066810696.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043756"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021369">
        <property type="entry name" value="DUF2985"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11204">
        <property type="entry name" value="DUF2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="473"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="634" mass="71618" checksum="573BDEB16CBCBE67" modified="2025-10-08" version="1">MLDVDGARVPQDQQSIHLRRLSGGSPTPAHDRNANPPQQVRSMLDVDDNTGPDGNTQATDFGGAEAGPAPAPAPAPAQAPERRGLFHRFSRATMRPEPANNPRRQPSQEDEYDSNIVDMLDVVDPEVSTLSSITNVQNSLFVPSLGRWVNRRPTYNLTRVSDMSGAFPSQDGGVGADQSARYTPEPRQQGVPQQGTDRPLKDVEEEDEEPAGRPSVERIPSYMTERFYAVRPSDTSLAHWSDEDLEELNDHVRHMLHSKRSAFKRSMKAFGQYVRRPLGFLVTLYAFLITVFGLAWVLFLIGWIYLGDEERRDYIIDVIDNVLVALFAVVGDGMIPWRLVDTYHMCFIARYHHLTWKLRNKMHVPDLKDHNDLPSEPVISRRAEQEDIEAQRQIHTKKGEEHSVLTPHQQAKLEHHQACFSKSHTFYKPHETETHYAFPLRLLVAIVVLLDCHSCFQLALGLTTWIIDYHVRPAAATATILCCSIAVNISAGVLISVGDRRTRKKDVVERMFRQELTQEAIRRIEERKEKEAEERNRLENIEEESPGKPRGASFDLGDRLKQNFIKPKNNDDGRARSLKSLDLARKQRKSNEIARKPVNRVGMFDTSVSGSLTEEGDDILGNPKPAHGASPPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPX3</accession>
    <name>A0ABR1WPX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670099.1">
        <property type="nucleotide sequence ID" value="XM_066811176.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044236"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="63" mass="6637" checksum="DF751CDF5E9E6C16" modified="2025-10-08" version="1">MRSRTPSTSFPDYGHRGLALDVLPDPEALPARLGDFEGGNVGRGEPAAVEGRHLLGSLPPDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQD4</accession>
    <name>A0ABR1WQD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670258.1">
        <property type="nucleotide sequence ID" value="XM_066811335.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044395"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="165" mass="18873" checksum="F3AEEA450EB1C613" modified="2025-10-08" version="1">MRDFFVFDSLDSILDIFWDILIVCVVCKVGLLYFIATFTTWGGHRWDMFLLFARVASTIVWARLFVHHYDLPKVRWFRLAIGFVCLLFTVAAEGGVALFLHRHYDGLMWSTPAETKIAYGTLLASYCLVPLALLGKNTEAPRKRQTPVRQEKDVKVSDGPSRVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQF4</accession>
    <name>A0ABR1WQF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668752.1">
        <property type="nucleotide sequence ID" value="XM_066809829.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042889"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="170" mass="18827" checksum="DE86C0223D8A0C3B" modified="2025-10-08" version="1">MRNWPRKPNGSLAFESSPGLCQFQLAPVASSSSPSLHHRYAADPPKVQSTHWALESHCQQQPEQSLASREQGSTQRTTRLPLQLHCPALSHPIQRERALSWTEQLADSDPAARDQSPPTTVAFVKDQDWPPLPEFLTCRPPQKTPSLQSSPIPPRLGQRKLDDVTGLAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQN1</accession>
    <name>A0ABR1WQN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669250.1">
        <property type="nucleotide sequence ID" value="XM_066810327.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043387"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="396" mass="44369" checksum="F1DAEB7048118548" modified="2025-10-08" version="1">MDSSRSLSREVSRGRTRRTSQSLAQDYQQQESRPSTPISVNERDKGYPPPRRSQSNSRPPVARKESAKSSKRPRSSSRSERFKGTTVDNALSSIGRAARRVLYPNAKNIEGCPGHGHHYCLFCMTHLDLGGKVSKDGKKIDTAFKVDEPPVIEVRPCLGDAAQFDPAKDLQLRSKINAESTAPGPVPARFTTPNRKWFAYCSSCGVTYLVGKAGKNFAADHPSHCATDMGDKTICVYVDAGVSEDEHGTLVGDSSVFFGPKSPLNALSTSTYDLEHQQTIQISALRRALRLSLKVMDQRKVLVAKEVITNSYEFIWQCTQFRLLILSRMEAVNTWLDFDRNAIGQGQLDPRVEADLQKIDEDVMRLASQGIVVQFFPLPAFDEYEPEYEFFYDRFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQQ8</accession>
    <name>A0ABR1WQQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_007144</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670382.1">
        <property type="nucleotide sequence ID" value="XM_066811459.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044519"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF315">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE MDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="9">
        <location>
            <begin position="26"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="9">
        <location>
            <begin position="314"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8085873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="489" mass="54693" checksum="46046A274CB3B2AC" modified="2025-10-08" version="1">MSLSPSVSNSAKSLTQLARSPLSGISVCVVGAGPAGVYTALQCWRKGHNVRILERNSAARTQGDFFMIAPQVVNHIKTWPDMADENDRIAADPRVSFHRNTGERISGPSPFSFDKSEGSNNTDELDPTRRFHFHHRHKFLQMLISQLECIGVQIEYDCCAAEFYEDVDKARVRLDDGRTIEADVIVAADGIGTKSHTLVNGQDIRVWPSGLAGFRAAFPVEMIADDAEVSERTKILDDGHPHFQLFHGLGLHMTIMRTEDIITWGMTHKDEGTASESWFANVDPSTVMNYVSTIPTFPSFLKRLIELTPKDGIVDWKIMWRNPQPLTTSILGRVVQVGDAAHTLLPSSMNGANQALEDAIYLAACLELGGKENVPWATRVHNKLRFERVSCCQKLGFVNLAKRNNRDAKTADSKKTEDLVPEQGRWLWGHDPEKYVRENFPRALDHLQKGTPFQNSNIPPGYVHEEWAVDELMARVERNEPLGLGGDWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQS0</accession>
    <name>A0ABR1WQS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_007163</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670401.1">
        <property type="nucleotide sequence ID" value="XM_066811478.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044538"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="CDD" id="cd19542">
        <property type="entry name" value="CT_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19545">
        <property type="entry name" value="FUM14_C_NRPS-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003417">
        <property type="entry name" value="PRK04813.1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="562"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1677"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="2723"/>
            <end position="2798"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="3779"/>
            <end position="3861"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="4793"/>
            <end position="4869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2695"/>
            <end position="2726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="4491"/>
            <end position="4522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="4491"/>
            <end position="4501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="4507"/>
            <end position="4516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8085892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="5316" mass="583779" checksum="1FBA8A464D8581B8" modified="2025-10-08" version="1">[encoded data, 5316 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQV7</accession>
    <name>A0ABR1WQV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669926.1">
        <property type="nucleotide sequence ID" value="XM_066811003.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044063"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="20"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="677" mass="75593" checksum="F5062A003C07E9F2" modified="2025-10-08" version="1">MDPTGSNEHDRRYLQIKFSQRWDYHRDTIRKMYIDDGLSTKHIALKMKEEYMFDADVRQYKYHISKWGLNKNISSTAKEQAIKALEKRQRKGTATGEAMSRVEPKLSSDAIIFARSDFPTQVHSAMLDAIDHQSPAGLTPSAISVLSPPQMPPGSSPATVLPLNNAPTPTTIAIRDRTWNDRATSLLEGRISIAWLDQFWHFSFKTFKHWGKGPRYWTATMLQFDDLLNMAPSPNTPGAITSSHEHASSVYSASPKGHGHLQPAALCRWSFHLTDEAIFDDEARSPPTEPSDQYDANNPDGWPSWPMESPPANPVTYLQEALRTNAFSNIEDDQLPLSSTQVAKAAAQSPEELLIESVGFAIMARNVELLGDILRRNASSDDFKLRKLYPFHLAASYLDGARSCCSIMNTLVCDTTAHNKINSLFINNLGHTVLDALMMTILKAHSSCSPEVVDGEFRGQQQFAGAEVDPCGRWDADSPCLRHSNASSRDHIPHSWKHMFCHTSVQAICHSITSVYQSSGAPDIGTRSGLFVISCGHCGNRLEPLPLHTLVLTTLFLAQNSCEGETLFGSLACLALLGVDDGEECTHQALDPLQLALCVPQSVSTTWSKEVQLGWAVFITVLQRAQQNEWESEELSEYQKEEHEQYLEEVRKCHKAHRWGEIPTAEDACAFYFSNMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRY7</accession>
    <name>A0ABR1WRY7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Solute carrier family 40 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006580</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in iron transport and iron homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669818.1">
        <property type="nucleotide sequence ID" value="XM_066810895.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043955"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17480">
        <property type="entry name" value="MFS_SLC40A1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009716">
        <property type="entry name" value="Ferroportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660:SF57">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06963">
        <property type="entry name" value="FPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="512" mass="56331" checksum="0FC23A067B733DB9" modified="2025-10-08" version="1">MASEQTPLLGTGETSGGDAPERQHHHPQEGIPRSITRALYASHVLSAWNSRLFQFGAVLYLAAIFPGTLLPMSIYAITRGLAAIVFAPAVGHYIDHGDRLQVVRVSIVGERFAVALSCAIFGLLVMRGSLSSRWKVGLLALLAFLACIEKLCSTLNLISIEKDWVVVIAGNDEAALRSLNAQMRRIDLLCKLFGPLFIALLVEISAGFAIWVNLGMSLTSVVIEYFAIARVYREVDGLQIPKNGPQVSRPDTPIDDDRAASSTLTHWRRIQAMFTKSAADFHLYFRHRALLPSMACALLYFTVLSFGGQMVTFLLASGYDSTRIGVARTFSVVFEVLATWVAPWLMGALGTVRAGLWFSTLQITMLVAGMAVFIAYREGDPVLAATGMVGSTVLSRVGLRGFDLCTQIIVQEDVKADIRGTFSSVESAWQNAFELFSYISTMIFFRPQQFMIPALASIGATAAASFCYAYFVYIRRGHLLHPEKLAGACGCWPVKERQRERLLDHINSERDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX50</accession>
    <name>A0ABR1WX50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670614.1">
        <property type="nucleotide sequence ID" value="XM_066806996.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040056"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="140" mass="14852" checksum="CD3235B6BFBFA88B" modified="2025-10-08" version="1">MAVIRNLDISDDEFDLIDPEPVSDMSDPESAGPNGKKHNFPVPITPQRTESVTTKLSAPGTFSRAPRDTEKNHAAPVSSRDATGAEDQRTYASTFGANKPSTADAGQGQSSGEGIPGLKYTKSVYQKLWGSKDALIAVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WX61</accession>
    <name>A0ABR1WX61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670640.1">
        <property type="nucleotide sequence ID" value="XM_066807022.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040082"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF16">
        <property type="entry name" value="ANKYRIN-1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="82"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="25667" checksum="87F5237293BAB734" modified="2025-10-08" version="1">MVQASSGFGELGNEYSNLVVYSIALGEPRPAEWLIERGVDVNAGIYRKQSALWAACANNAPDSFIRLLLEKGAKVEPATTTPGRTPLQIAASKGYIAVASLLLSHNALINTECTSLCGEPLRMTALDWAATMGRLDMVLFLMECGGRSACRALTDYDGAFWHARGHLGVLNFFERYTRVSFAVVMPSLRRKFPDMLVSDQNIIDLTRYEDWNSETNWNADDWSSKDEFEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X047</accession>
    <name>A0ABR1X047_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671684.1">
        <property type="nucleotide sequence ID" value="XM_066808066.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041126"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="222" mass="23717" checksum="C1759A5AEB9C5CDC" modified="2025-10-08" version="1">MSLRKIGPGFYIATIPPSMEYCFEDMCDNFTETWKHLPTGHVGGALAQESSTDPDDHHPGHPGASTGTGNPHPHEPTQCKGLCLTYTFAQRAGGPPRGGPMPARPDPCTPKGHSIVMMPAVQPKSMPPPGPGLRDSNVHLILVVPKEDEEGQAPDNRSQPPPPRPHSYIPKGRSVTANASGPPRSPRSMSSQPSTSGGGHSRDRIGPVLVVWRILVHDYLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0M7</accession>
    <name>A0ABR1X0M7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 13">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="8 13">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PG997_003876</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; pentose phosphate pathway; D-xylulose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 13">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="8 13"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671809.1">
        <property type="nucleotide sequence ID" value="XM_066808191.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041251"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004076">
        <property type="entry name" value="PRK05581.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="12" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00013920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK8088915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="249" mass="26812" checksum="D439B946AD0E0E7F" modified="2025-10-08" version="1">MAPKAIIAPSILSADFAQLGADCVRTMEQGADWLHVDIMDGHFVPNITFGAPVVAKVRKHVEPPSGKYGRGTFDCHMMIAEPKKWVKEFKNAGCDLYCFHYEAAFSSAAETPEGKSDQKTNPKELIRYIHDCGLLAGIALKPATGVDVLNEILESPDEKERPDMVLIMTVEPGFGGQKFMASELPKVQALREKYPNLNIEVDGGLGPGTIDQAADAGANVIVAGSAVFGAKDPSEVISLLRDTVNKRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1J9</accession>
    <name>A0ABR1X1J9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Geranylgeranyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004206</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672139.1">
        <property type="nucleotide sequence ID" value="XM_066808521.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041581"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF44">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="13"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="413" mass="46906" checksum="608C3563A5025B76" modified="2025-10-08" version="1">MNLVPNDTSFQYKTMLPSASSPPPLSIPQRHSSPNLVHRPHGPSRPLQVGITACPRVGLAGPEHSIQAPPQLLCHYWPNTWPFFRHHASLRPSDPSRFETEDFNFAARKTWTDQKEKILWGPYDYLAAQPGKDIRKKLIAAFNTWLNVPDESIEIITKVVGMLHNSSLLVDDVEDNSLLRRGMPVAHSIFGTAQTINTANYMYFVALQEIQKLNNPKAISIYMEELLNLHRGQGMDLFWRDTLTVPTEEDYLEMVDNKTGGLFRLSIKLMQAESPSSLDCTELVNLLGLIFQIRDDYMNLDSAVYSKNKGMCEDLTEGKFSFLIIHSIRANPSNLQLINILKQKPTDEEVKRYAVKYMHETGSFAYTKKVLDVLIERARKVADKIDEEKDRNEGIHRILDAMVIPDTENGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1N2</accession>
    <name>A0ABR1X1N2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosome-interacting GTPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004299</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672232.1">
        <property type="nucleotide sequence ID" value="XM_066808614.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041674"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1070">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="65"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="291"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="42636" checksum="A441261AE5259C0B" modified="2025-10-08" version="1">MSTTVDKIKEIESEMARTQKNKATSFHLGQLKAKLAKLKRELLTPSSSGGGGGGAGFDVARTGVASIGFIGFPSVGKSTLMSRLTGQHSEAAAYEFTTLTSVPGQVTYNGAPLQMIDLPGIIEGAKDGRGRGRQVIAVAKTCHLIFIVLDVNKPLTDKRVIETELEGFGIRINKQPPNITFKKKDKGGLNITSTVPLTHIDHDEIKAVMNEYRINSADIAIRCDATIDDLIDVLEARSRSYIPVIYVLNKIDAISIEELDLLYRIPNAVPISSEHGWNVDELLEAMWEKLQLRRVYTKPKGKMPDYSEPVVLRSTRCTVEDFCNAIHRSLVENFKTAIVYGKSVKHQPQRVGLSHELADEDIGNVSTIPLPLPPEAEPWPACANPSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X222</accession>
    <name>A0ABR1X222_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_004434</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672367.1">
        <property type="nucleotide sequence ID" value="XM_066808749.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041809"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052239">
        <property type="entry name" value="Ser/Thr-specific_kinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998:SF2">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="32"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="164"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8089473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="264" mass="29231" checksum="11FCA97249DF0110" modified="2025-10-08" version="1">MAQLLQDLIYSFGNCLNCFPGSPTLKINSRSFKILRLLGEGGFSYVYLVQDTATAELFALKKIRCPFGAESVQQAMREVEAYKTFAHSPAVIHSVDYAIASERNDPGSKTVYVLLPYYRRGNLQDIINANLVNHTQFPEKKLMILFLGVCKAMKDMHQYRAPAGGERMEAGNPKAGDPEEAAAGRSSKGKNKRNKAMAASDADDETEQARPLMVDEQVAGPGEHRSYAHRDIKPGEFYGPLMAGENEDYREHLTTDYGALQAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X225</accession>
    <name>A0ABR1X225_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 9">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_004348</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 9"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672281.1">
        <property type="nucleotide sequence ID" value="XM_066808663.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041723"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="10">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="148"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8089387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="331" mass="34423" checksum="DAEA6462020B8CC1" modified="2025-10-08" version="1">MVKAVIAGASGGIGQPLSLLMKLCPLVDELSLYDVVNTPGVAADLSHISSTAKITGYLPKDDGGKAAMKDADIIIIPAGIPRKPGMTRDDLFKINAGIVKGLIEIAADVAPKAFILVISNPVNSTVPIAAEVLKAKGVFNPQKLFGVTTLDIVRAETFVAEIAGKKTGSELTVPVIGGHSGETIVPLFSQISPSGISIPDDKYDALVNRVQFGGDEVVKAKDGAGSATLSMAYAGYRFAEKVLKAAKGEKGLVEPSFVYLPGVPGGKEIAEKTGCDFFSVPIELGPNGAEKATNVLGNITEKEKKLLDACTTGLKDNITKGVTFAHNPPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2E0</accession>
    <name>A0ABR1X2E0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-directed RNA polymerase II subunit rpb4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPB4 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672388.1">
        <property type="nucleotide sequence ID" value="XM_066808770.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041830"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045222">
        <property type="entry name" value="Rpb4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21297">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="5">
        <location>
            <begin position="27"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="144" mass="16064" checksum="95204EB614462294" modified="2025-10-08" version="1">MSANQQTSRTKPVPAGNEEASSELHLGEFQDVDTLSLSEASLLLNAISESRRKGKGEAHETEMLSKTIDYLDAFSRFKNKENVEAVERLLGAYPQFHKFERAQLGSLCCDNAEEAKTLIPSLQDKISDNELDDLLNEVGKFMNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2Q0</accession>
    <name>A0ABR1X2Q0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004649</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672582.1">
        <property type="nucleotide sequence ID" value="XM_066808964.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042024"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.20.20">
        <property type="entry name" value="Receptor L-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051648">
        <property type="entry name" value="CWI-Assembly_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036941">
        <property type="entry name" value="Rcpt_L-dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018:SF3">
        <property type="entry name" value="RECEPTOR PROTEIN-TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12454">
        <property type="entry name" value="Ecm33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045163011" evidence="7">
        <location>
            <begin position="22"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="340"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="392" mass="41364" checksum="0DB0883B5B462C94" modified="2025-10-08" version="1">MFTKQIVSAIAAVGMATGAMAFDCKDDLIKISSSGDATQLGQRYCYPGDAELDFGKLSQIGGDLTCENNGQIISLKAGSLTSIGKEFRLQNATQLSNLAFTSLNSVGSLKFLSLNGLTALNFGSEGVKKADTVIISDTRLSSLEGINVETVKDLDINNNKFLTKFTSSIKSLSNLLNINANGLKLSVEMPNIEWLANATISNVTEYSSPSLATVNGSLRFDSNFFESVSLLNLTEIQTGDLSFVGNSEVKNISFPQLTKVGGGFTIANNTALEKLTSFPKLAMIGGAVRLRGSFDDVKLPALDDVRGVFQITSTENIQSSCDEFKKLGNKVAGDGGNIDCTSNNQNANNDTSSTGSSDGSDGDDKSSASSMSMSMSTVFSLATVGALVTFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2Z5</accession>
    <name>A0ABR1X2Z5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004743</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672676.1">
        <property type="nucleotide sequence ID" value="XM_066809058.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042118"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050259">
        <property type="entry name" value="SDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="29954" checksum="B37D746759E5BA14" modified="2025-10-08" version="1">MTDRISQIASHLNWPKGMLAGQVAIITGSGQGIGAEAARLFANEGAKVVVSDIDSAKAKAVADSITSAGGQAIAVPGDMLDDAYLKTLVKSAADFSGNGKIHIIVNNAGYTWDGVIHKMTDKQWDAIVALHCTAPFKLVREAAPYFRVRDGEPRAILNVSSSSGVHGNAGQANYALAKAGVTGLTKTIAKEWGPAFGVRANTIAFGHIATRLTQAKEMGVFVTGPGGEKIAIGIPEAQKKAAGPALYTDIPLRRPGTATEAASAMLAMCSPMFSYVSGQTLMVGGGRNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X345</accession>
    <name>A0ABR1X345_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Partial AB-hydrolase lipase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004801</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672734.1">
        <property type="nucleotide sequence ID" value="XM_066809116.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042176"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="3">
        <location>
            <begin position="272"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="730"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="748" mass="84810" checksum="93C6A2EB91DB99FB" modified="2025-10-08" version="1">MKASAENMQAGGSQPAGADHVQAAIQFTHQAEKLSLQPHNAEHPENIAVNAQFITPQDAVVVTADGNRLPGPPLQEAVKLNELKDDLDSNHSTDDIKSIERATHDSADQGRDATGPTEVELEAQANSASMQKANDGSLQRTMPPSHTNPLFPPLPLYGPSSVFREVQCMTFRVSSFFLSTGFLGVVVLGALFTSIPPLFYRTWMRLTLRNPDARRPFYEEEVRRKKARQEMDRAWKRRKTQDKISPDKEAPVANDGFVPTEGGPDPIICDVGYYARRVGLDMEEFQVQTEDGFIIDLWHIYDPKEHTKLDEKDRTFRGPNLFTGETKKRPETPGQKRKFPVLLLHGLMQSSGAYCVNDEDSLAFYLCKSGYDVWLGNNRCGFKPKHVSLEYADPRMWCWNIRQMGVFDLAALTSRVLYETGFEKLGLICHSQGTTQTFVALAKEQRPELGEKISVFCALAPATHAGPLIGKAYFKFMRVISPAMFRVVFGIHAFIPLMMTMHGVVPARIYGWLGYKVFSFLFDWADTRWDRALKNRMFQFAPVYVSAESMRWWLGRECFAKHKCILSTKEDLHAEEREDAETDGPLANPTEMEDSGLLQRLRSRFTSRSRSHSHPHEHHHKRLPKGATAWYNEQAPPMALWVAGNDDLVDGSKLIRRFERGREPHVQIVHQKTIVEYEHLDVIWAMDAVDQVFSEVREVLWKTCNVREQCRVPKGCETVEAWTPKMIDPAAMDADQSSSDSSSEYTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3D5</accession>
    <name>A0ABR1X3D5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004815</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672748.1">
        <property type="nucleotide sequence ID" value="XM_066809130.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042190"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF115">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="21"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="121" mass="13158" checksum="B9CB8FEAE9F056B3" modified="2025-10-08" version="1">MSGKFEPKVPVNLNPPKDDPISVQDLAKADGTEGQKCYVAIKGKVYDVTGNKAYQPGGAYNVFAGKDASRALGKTSTKPEDVQAEWQDLPDKEKGTLNDWVTFFSKRYNVVGVVEGATNME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3I1</accession>
    <name>A0ABR1X3I1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome c oxidase assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_004929</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PET191 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672862.1">
        <property type="nucleotide sequence ID" value="XM_066809244.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042304"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018793">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_Pet191"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10203">
        <property type="entry name" value="Pet191_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="100"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8089968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="130" mass="14754" checksum="6651107FBABBEAC1" modified="2025-10-08" version="1">MPSSCKEIRAALAQCLQESECVMVQRHTAAECLRSPLAETLPTKCQQLKKGFGECRRGMIDMRKRFRGNQPITFKNLEASDSGEGYQLYAGRSAFAGSVRKTDGNEPEPKDWREVENEKLRQEQADKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3S6</accession>
    <name>A0ABR1X3S6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger CCCH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_005030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672963.1">
        <property type="nucleotide sequence ID" value="XM_066809345.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042405"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46156">
        <property type="entry name" value="CCCH ZINGC FINGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46156:SF1">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="297"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="297"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="364"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="377"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8090069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="419" mass="46059" checksum="5AE6382391960B3A" modified="2025-10-08" version="1">MSTAEEQELMAQISSLAGRINRHKAQQTGHSGHPNRESSVTQERRRHDANSIQQDATHPTRGAFRVAPYPHGNYRGGRGGRAPAYRNKTLVLNGQARPVATSDDSTPTPTTPNGSSWVTKTDRHLQLINTNVFEKESQNRANAIEQTQRNKQLQKNHVEKARLMNYLGKESMTSVTPTSNTAATPSSYEVTVDGIRFHVTRQGSKLVRATGDQNPPSATPRVTTIGGVKFFRTKNGNLIRHGVAKAQRLACGVKKVDELCKTFSWTGCAVVAICRDWLLKGQCQKGDACDLSHDIAEERVPLCMHFANGNCRNEKCSYLHVEHSQTDLVCRAFGFCGWCDKGASCAERHVFECPDFSNTGAGNKDNAAQEGEISDLSSDDDDDGASNDLDSDEVEEFIGKDDEVQDLDFAAQKDFIGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X484</accession>
    <name>A0ABR1X484_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Store-operated calcium entry-associated regulatory factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Transmembrane protein 66</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_005163</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SARAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673096.1">
        <property type="nucleotide sequence ID" value="XM_066809478.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042538"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009567">
        <property type="entry name" value="SARAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929:SF0">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06682">
        <property type="entry name" value="SARAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="211"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8090202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="342" mass="35723" checksum="F9D611E2F39EEA99" modified="2025-10-08" version="1">MQLNLPRPSGAPSSSSSWRRRPPRPPRRPKSPKNAILLSQVQTLTLRGAGAQTTHRRVPAMPQLQCVSKPANLCRLHEIDVMRCTNQGPGYETEDIQWSCTASLPPELKLGGTDVMCEGYSSPDDDYVLKGSCGVQYRLILTAEGERRYPELAGGGGRRGGGGGGGNNSAPEIFGINAGTFIFCMLFLGVVGSMIYHAWLNAYGNNNNGTVQRRPRGSGGGGGGGGGWGPGGGGGGGPRFDDNDDPPPPYSSKRSSSSQQQQQQGWRPGFWTGAASGAAAGYYAGSRGNSSRQQPPPQRNYGSGYGGSGSSSGWGAGPSYSSSSSASSERHESTGFGGTSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4Y1</accession>
    <name>A0ABR1X4Y1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673362.1">
        <property type="nucleotide sequence ID" value="XM_066809744.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042804"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="103" mass="11904" checksum="278C678B28C5BAAD" modified="2025-10-08" version="1">MCTEQTVWYPCRTHAAMKPITQYCEQYDRSSRQKQHCGRVTDSDPFVAQSLRAHLDEPCPHGCKARPGPIQWTPLLRKGSKKVRRSLVSGLRRTRRGIKQALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7I7</accession>
    <name>A0ABR1X7I7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673392.1">
        <property type="nucleotide sequence ID" value="XM_066806096.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039156"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8091420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="246" mass="27770" checksum="9EB3BA66E613F038" modified="2025-10-08" version="1">MSSSEKGPISREIYTERLLYYIYDWLVLGFNMKYLWRCPTKSVLLPFFKENFSANHLDCGVATGYFPAACLESSGGSKQDEEQNQRLALLDFNPNCLRTTERAILSRVGGRRRRPIDIERVEADVTAPLPAALQDAKFRSISMFNLLHCVPGGAAHKVQSFRTLGRVLDPDGGVLVGCTVLGEQYAARWWLSRLAVRHMNRVGVFHNLDDNREDIEKALGDAFEDVQTWLVGMTLLFKASKPRANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7K7</accession>
    <name>A0ABR1X7K7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleolar protein Dnt1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673443.1">
        <property type="nucleotide sequence ID" value="XM_066806147.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039207"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
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        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
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        <location>
            <begin position="552"/>
            <end position="563"/>
        </location>
    </feature>
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        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="784"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="877"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="900"/>
            <end position="911"/>
        </location>
    </feature>
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        <location>
            <begin position="932"/>
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        </location>
    </feature>
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            <begin position="950"/>
            <end position="961"/>
        </location>
    </feature>
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            <begin position="1001"/>
            <end position="1018"/>
        </location>
    </feature>
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        <location>
            <begin position="1078"/>
            <end position="1092"/>
        </location>
    </feature>
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        <location>
            <begin position="1118"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1138"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1156"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1185"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1216"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1252"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1284"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1345"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1366"/>
            <end position="1381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1381" mass="152021" checksum="FC58C897589AF818" modified="2025-10-08" version="1">MPRDKEETKVAPRAVRVFMHDHSKRNEPEHAETLGRYRMNMMENDTFADAGLKALQRFRQEHPEQGRRVKVDIIMDKEYYKFGLDETLETLQDGEPLHIFLTEPSSTLSQETPKTPSTKNKTKSPQSQKGPATPNHAKSAKGTPSNPNRQTPASGSALRPSPKSKETAAAPTPQIEISSDSSNLSRSSSEDTDCIFMGQTPDGTQKTAPTPKAGSKGSQTPTRDGSINRKVSSSLPNNRTPVPAAKKITPGHEHPVQPQASKEPETSLPPNSSKSPKCTPSSQKQRRPSSSLQTAPSVLAHASPAKAKTESKTPKFQPAPSRASTSSSSRSRNQQKDVYDVPSDTDDGEFITPQQDTDLRARIRALQDDVVPSSLLPQKGIKEQTASSRKPPPTPKAKVITIKDSQDSVSEESDEDVRIIAKTPDSYTVKNTRGTHSVAHLIERLGEHSRATKKRLEEEAAAEEAAKKEKAEAEARNKRVSSRDAIDQIKKTTNRKVEPRSMIEEIPDSFFEDTDLSDDHLGDDIIKGPSQSSSSFVTADETPRPEVKRRQTTPTTAFTPINTLYPKQREQTNFIPTGKTFGLNYPKHFRDRFSDAEQSDEDDEASVGSEEEKFWRGEVLDEADGLPKAYKEYSWKYKTSFVSLGDRGYTYVGDGPWEGLILNAEEERNAEPRSQLSNLEESDGDDDEEEKNAEPEVKPNDLEESEAGDEEDDAEQVQLPPCSLKLATPNSTTPTSRRQTAQDAKVSDESDLRSADSEASSVMIRRQLEAECPPSNQQLGMLMSSSPSSRTPTARSKVAPTRSASASRYDDSPDQSDDDEDTPKPISKLVVNNSGLSEGRKATIKKVTFSDEVKGEDDDETTPRPKPLAEVNAETSENSEDDVEERDETILAPKPLAEIAGEEASDNEDGKEESQASRVSALDYVLKESPRWLNNLTTTSQAQGSWKGIGQSSGASSSPSRQRQKSESPSCSAPPRFRSYTPIPPPVIPTFRATTPSPPAVEDRKLNNSFGSERKRLASEPPRSATPATAPIFRSFTPAPPKSATQTTAPVFRSFTPVPPPSLPAYPRATPAHCKPSVDNSFSSQKSTSDAVQKQPEVPDGLETPQKKCDNLWNSILSSPAASEAASSKSSAKKRRRRDSESRHSEVPVEESSSRKEKHKSKHHKKNKSARKSRHEDQQQQQQDQHSHGDGGETKATHFGDAESVVSGLKLDAKNKYKKKYKHRKSLDDSIPPRMSVKVKVEEVEEDDSSHKKPKSSKKHRKSLDAEDAPSRKKRKHNHGDACAPTTAAANTTYAPIPTTAPPQQAMTNKPGSAPMTPRIVDQKNEEHKRPKSPATEPNSLPLPRRNRKQKNKKNRVSYRRRKQGLSKTDSVSATSPSVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X821</accession>
    <name>A0ABR1X821_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">17-beta-hydroxysteroid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001934</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673545.1">
        <property type="nucleotide sequence ID" value="XM_066806249.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039309"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF7">
        <property type="entry name" value="RE15974P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="3">
        <location>
            <begin position="16"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8091573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="263" mass="28094" checksum="44EF4AEE9A2266A7" modified="2025-10-08" version="1">MVSNTTKPLPFRLDGKVALVTGSGRGIGAAMATELGRAGAKVVVNYAKSKEPAERLVEEIKQLGTDAVAIQADVAKVPETVRLFDEAVKVWGGLDIVCSNAGVVSFGHLEEEEFDRVFTINTRGQFFVAREAYKHLNQGGRIILMSSNTASAFAVPRHSVYAGSKGAIESLVKTLKLDCGKKKITINAVAPGGTVSDMFHDVSQHYIPNGEKYTAEQRQEMAAHASPLVRNGWPVDVANAVVFLASREGEWINGKVIGVDGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8W0</accession>
    <name>A0ABR1X8W0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673863.1">
        <property type="nucleotide sequence ID" value="XM_066806567.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039627"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="423" mass="48101" checksum="762E91CC433B09E2" modified="2025-10-08" version="1">MKAVVVEETAKQIEKRLGINWSPAQKKKYLHSIKTVYLKRLETPYPINNFYTAGTQKAQDEWDAYWKGKPLKDPRYNKGLRRGTKTIDFSKLQYIIEQDESVQFRDEDTKELVMVVLRNFFPDEAMREAFTEICLDVVDRRREDPGQLCHFGYTCGSRHQPGLRLTTCNKRLNTPARQAYERRLNYKAQGMASLGWNMLKSRLPDEIIQDYEDAIANSGAPRMDMMREEKNFSFEFNGKSVTFDDLDLAPPSELCSINYSRFTHKENNGNRFFIACATQAPADPTKGGNFYNASYGIMLKAATNTVTSWMPKDYHGTTLYEMVEGPEKRAGYEVRPDGGINTGFSFEVSKMIRNAVKQGDKRKLDSSSSSASASVSVSSSSAAEEITVREPRAFKKQRVARRRRVAAAAVDGDDQDSSSDYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9X5</accession>
    <name>A0ABR1X9X5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674224.1">
        <property type="nucleotide sequence ID" value="XM_066804451.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037511"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="159" mass="17573" checksum="BB3BAB03C0B66AB4" modified="2025-10-08" version="1">MDATLAIASLVRENALKGAEISSAIFKLLSSTPPHAAPREVYDVAKAVSELSGNVGRITRVWPAPKFHSLYTTKETLGRQATITLERISLLYDEIQALIDSGNAAARLLWAFRRTRWRLLLLQADAYSTGVRIITNTMVLAEQLRNAHGYVSSNLPKCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAI7</accession>
    <name>A0ABR1XAI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674433.1">
        <property type="nucleotide sequence ID" value="XM_066804660.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037720"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="249" mass="26704" checksum="6FC6D6586CBF7A4A" modified="2025-10-08" version="1">MSSIAQQGAGFKDAATALRTLDLIAHRSLLYQHQLVRTYIARAQTHSHAATSPGMAAAAAVFEAWQSSTLPALRSQLRCRLGNGNGNGGGSSSSGGGFRPLVPKDVLAALQPLLAQIEAETNHAASVWGAANTDPPFWTVGGERGAGAFMRDYLASSPRAKLGNLVLGPTAGTAREEDWETVRYGALDGMVPADRETAEGWRKEELWEADGCTPTRGHLRMLVWAWSPVPTRTLVDRIRKFVEALAARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB39</accession>
    <name>A0ABR1XB39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674668.1">
        <property type="nucleotide sequence ID" value="XM_066804895.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037955"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045753893" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="12339" checksum="67D1FB4B8D8FCEEC" modified="2025-10-08" version="1">MKTKRGSGTIPSLLRWGCVLPSWCLPVVLFDSGAGSSVGGDGCGSIGGGAGGSKDATTAATAALLLLMVLPELPMRPNDQHESRQGPSGSSALWCNYSYQPKLQRPNSYLMGVIDARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB87</accession>
    <name>A0ABR1XB87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000640</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674728.1">
        <property type="nucleotide sequence ID" value="XM_066804955.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038015"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045751687" evidence="7">
        <location>
            <begin position="18"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="549" mass="61871" checksum="E1C32342B7E3FD89" modified="2025-10-08" version="1">MLSYILLFLASLALVFTARRRLHPKPFAGIPYNKQSAHRLTGDIPELVPVIKATNEYSASMFAISTQQLRQPSRRCCSLRRGREFDRAPISIKTLKNFFPYSFMGKYNTPEIKEQKRVWADAFGADFLRRVAAPSIYKATLDLLELWRLKADGRSFEVVEDLHNATLDAIWVALVGEEAGITRHEIKKLLQSQSDAGDGGHCDLGPPPRGYRLRSEVDYVSEMIAKNSSSRIPVLVQKLAAYLPRHRQFRRTVDTEIGLVMRKAVDRFQRLELGKLEAGENDTCMMDLVLRRKVLEAKKSGRPLMDPTKDKVLLDDTFLMMFAGYETTANSLIWFMRYMESYPAAQADLRAALKAAFPHTTTPSVDELLGADIPYLDAACEESLRLAGVAKGNLRQAVVDMHILGHFVPKGAEIFMNYHVDHAPYPVDEEKRSASSRAAEAKLAAREGILRDVDVTRDLGSFEPRRWLVKDEKTGKEVFDAYALPQLAFGGGYRGCSGRKLAVMEFRTVVALLVLNLEFLELPEDMKTLNASETIFRLPDMTFASLRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBE0</accession>
    <name>A0ABR1XBE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674783.1">
        <property type="nucleotide sequence ID" value="XM_066805010.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038070"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8094010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7293" checksum="F22F47D45957CAC2" modified="2025-10-08" version="1">MQQETALRLEAVNKAVGNVRHRQISPSEITTITIVCIVGHPLALVALAHHNCRGPGRVQEEDARESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBY6</accession>
    <name>A0ABR1XBY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000836</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674924.1">
        <property type="nucleotide sequence ID" value="XM_066805151.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038211"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF15">
        <property type="entry name" value="ACID PHOSPHATASE PHOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045712917" evidence="3">
        <location>
            <begin position="24"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="383" mass="42381" checksum="A6424353E37E3C6F" modified="2025-10-08" version="1">MPNNFLCLLLLVGFLVGLAPANSAIVPGRVFDRFISIWLENQDFAQVIKDPDFAVLKRYGILQTRYYANTHPSQPNYLASVAGDYFGLNHDESVRVPDNVSTIVDVLETRGISWAGYYEHMPGPGYLADFSLDANGTWDYVKKHNHFASFDSINKNGTCLAQLRSFEAFKRDLAAGTVPQYVMMSPDMRNDGHNTTLEYATKWAHEFLLPLLDDKNSLRKERTVIQLTYDEADSYDQPNRIASLLLGTGVPKSLEGTEDATFYTHYSVLATAQSNWDLPNLGRYDAAANVFQFVADATGHANRDPANLAALDNSWSYAGFLHNETASQLPVPPPNLKLVGAGGQGVLPIVQSIWKGLAGEKSPYDSSGNVYDGKTVPVYRPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCG1</accession>
    <name>A0ABR1XCG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Snf7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675158.1">
        <property type="nucleotide sequence ID" value="XM_066805385.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038445"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="227" mass="25379" checksum="97FB59084A629D80" modified="2025-10-08" version="1">MESLKALFVKPDPNAQMRKCNALIRSNIRKLDRDINSVKAAEIKTKNYIVAADRRGQRNPSQQKQAAKEARDFARELIRVRKTSARLTTSKAQLNSVQMQVNEAFAVRKIEGSIKASVGIMKDVNRLIRLPELAGTMQELSVELIKAGVIEDMVSDTLPEDGLFEDEEDEAEGEVDKVLGEILKGKMEKTGTLPSAPIAQEPVAAEEEEEDQEAMMQMRNRLEALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCZ8</accession>
    <name>A0ABR1XCZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SART-1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001123</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNU66/SART1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675211.1">
        <property type="nucleotide sequence ID" value="XM_066805438.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038498"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005011">
        <property type="entry name" value="SNU66/SART1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152">
        <property type="entry name" value="SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152:SF5">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03343">
        <property type="entry name" value="SART-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="17"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="69"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="252"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="486"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="570"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="261"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="337"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="409"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="579"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="597"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="627" mass="70500" checksum="6ADA747F7CCA1D27" modified="2025-10-08" version="1">MDPAEIAEFNRLRAEQGLAPLPVPGAAGPQFKEAASDDEEEEPASTLETREAAAYDNFKKIQDAEAAKKRRDEKAAAIKKARDAAKRTEQLEGKGLGEADEGEGVDAKSWLMTQKKRQKRIEKARKLEEEMAAAEAAAAAQVKYESKDLAGVRVAHEISAFEDGDEQVLTLKDSNVIGDDDEGDELENIDLRDREKLSERLDLKKKKAAKRFTLDAQGTSYQAQVAEGQPQDRRLQQINLDIFKDEQPSSDYLDISEVKVKKPKKKKKTTRQRPLDEDDISPSAPAADDQSMDIDSGAVSFGRKRKVEDTSLADDEDLQATLTKQRKEALKKRKRVRPEDLARQLKEESETPGPENDEHSENQGGLVIDETSEFISGLKKEDIEDRKQRKSKTPNPEAATAMDDESDEDKPMVDRDEVEARQRETSAPAEAPVAGVDEEKTIGSGSGIGAALQLLRERNLIKDSNSSEMNDNLRHQQQFLAEKKLREQKIEHDARSQRERDRASGRLDRMSAREKEDLARQQNIMRDQQTARQMAELYNRGYKPNVQLNYVDDHGRSLDQKEAFKHLSHQFHGKGSGKGKTDKYLKKIEDEKRRESQSVLDSSQNVGMSSAAAQQTKKRKEAGVRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD03</accession>
    <name>A0ABR1XD03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcipressin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RCAN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675343.1">
        <property type="nucleotide sequence ID" value="XM_066805570.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038630"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006931">
        <property type="entry name" value="Calcipressin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10300">
        <property type="entry name" value="CALCIPRESSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10300:SF14">
        <property type="entry name" value="PROTEIN SARAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04847">
        <property type="entry name" value="Calcipressin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="149"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="200"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="229" mass="24939" checksum="4F2604DAE108DF42" modified="2025-10-08" version="1">MSGSPTSLPARPEFSRMRRASSLKLDLSSLPPLTQPTPPTNTLLLTNLGDLDIFRPDNLQTIRELISTTAPVYTWAPLKSFRRIVVSFFDEESAIKVRQVWDGEAIMGQRCRPSPSPPHGWEQTLEDAPNKLVHADDLAAALAKLHHRAPDAAMASPVSPTDGNSATTRSRSSTLIFQPKESTGNSPTLPSIAVDDMTDSPMELNSPSPLSSPKPIMAHTSRPPVELME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD97</accession>
    <name>A0ABR1XD97_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001228</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675316.1">
        <property type="nucleotide sequence ID" value="XM_066805543.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038603"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF82">
        <property type="entry name" value="FAMILY CHAPERONE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G08575)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="634" mass="70303" checksum="F7763D998F2FCDFB" modified="2025-10-08" version="1">MSFNLPLRSTPSRRNQESRANSQNYFSGYTPPSSTEAINGPVRELAPVSDRLIVGVDFGTTFSGVAAVYASTPDDIEIIKTWPGGNGITSDKVPTEISYDIPPTAPVGTSPNIKWGFQFKPEEPRLRCIKLFLDRSQKLPFYVSPQETATQLRKFNKNVVDAVSDYLTQVYEHTMDTLTRRYGESFMASTKVDWVLTCPAVWSDAAKNTTLQAAERAGMGSQADIQMISEPEAAAVYTLKAIQPNHLNVGDNFIVCDAGGGTVDLIAYKIISLKPLRVEESAVGTGGLCGSAFLNYRFEEHVKGRLGVSRFDEMKLKKNKTWQMGLRYFEESVKRNFNVDDDQEVNIPFPGLPDDEEAGLDCGFLVVSAAQIKEIFEPVAKEVCDLVQGQVDTVRSKGGIVSGIVLVGGFGQSDYLYRRLKAHFTSAAPPPYTERPTHSSGNAIIENGSIEVMQPLYAWTAVVRGAVLRGLEGNMVISRKARNHYGTSYATVYDEDKHSVSERYWSPLWERWMVSDRMQWHIAKGEAISPLSPIAFHYTRNFRPGQSLVVTDDLIACEADEPPAAYNRELAHVCTLTTDLSAVPRSLFTRLTTTRGVEFDNLDFTLEMIVDSAGLGFELKVDGVRYGRVEADFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDM5</accession>
    <name>A0ABR1XDM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675555.1">
        <property type="nucleotide sequence ID" value="XM_066805782.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038842"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046027006" evidence="1">
        <location>
            <begin position="18"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="177" mass="19351" checksum="D4EE6B65B738ABE6" modified="2025-10-08" version="1">MTSIACASSFFFFQTWAVGSHYTESLCRNIGTGSIRRAVPSPIKMRLRPVETNQRTDSRRLLSVSFAFESHSTSVKATAPDQPPPQTRYGFSASIQSLKLAPPARILLWKIREGPQKAPVTKTPNATLGFAATVLIVSYQSTLPQPNLWNFWNLDPSKQQLKLQVDGTGTSAAAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEF9</accession>
    <name>A0ABR1XEF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein kinase-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675756.1">
        <property type="nucleotide sequence ID" value="XM_066805983.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039043"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="115"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="47019" checksum="14CF36E2AA5796DF" modified="2025-10-08" version="1">MANTRPNQEGFHRRLEAVQAILRQYGLTSAQVTPVAYVEHCPFMFNNYIFKVDLAAPATPSSFPGNQPCTTPPPPAGVSSLIVRMSNPLAEGLNNANRVENDVAASYLIRQSVTRAGLAPVVPAVFAWAPNRFPDVAGEAGFGWTMAEFKPGADLDAQFPTLDRDAVNAVLEQLADLVVAVQRVDLPSGAARFGALTIDAQGAIVSGQMPLLKGGPWDTYAETWVAKLKDRLAESDQSSLLKGWRESGIRERIDKYISAGGVQLILEPVDNNQKILNHGDLTLNNLLYDSDTQRITGLLDFDWAAVTHPCDEFLFGLWDIGGGIHERVGDLQPYIISGDFSQQPDGLSEEEVRKWETAKAWDGALARRGAIRPSSIAGVDRIQALRGLEELLCPFALASEVMLGRISDAEKVAKKEEAGVKITDWLDRWAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEP2</accession>
    <name>A0ABR1XEP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675796.1">
        <property type="nucleotide sequence ID" value="XM_066806023.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039083"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10221">
        <property type="entry name" value="ASKHA_NBD_Arp3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8095023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="439" mass="47770" checksum="D70FF314E952F051" modified="2025-10-08" version="1">MANQTPAVVMDNGTGFSKLGFAGNDSPSFVFPTAIATKSAGGGGGGTGSGRPAVANKPTFLTGGAGPSGHLSGKRGTEDLDFFIGDEAIAASGGPGYGLHYPIRHGQIENWDHMERFWSNSIFKYLRVEPEDHYFLLTEPPLNPPENRENTAEIFFESFNCAGLYIAVQAVLALAASWTSAKVSDRSLTGTVIDSGDGVTHVIPVAEGYVIGSSIKSIPIAGRDITYFVQSLLRDRGEADSSLKTAQEIKEEHCYVCPDIVKEFSRYDRDPTKFAKHTVRQPGGREVTVDVGYERFLAPEIFFNPEIYSSDFLTPLPVVVDTVIQQSPIDVRRGLYKNIVLSGGSTLYKDFGRRLQRDIKHLVDARIRASEVRSGGARSGGLEVQVITHKRQRHGPWFGGSLLGQTPEFRSYCHTKAEYQEYGPSIVRRFALLGGPGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ10</accession>
    <name>A0ABR1UQ10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8060998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660418.1">
        <property type="nucleotide sequence ID" value="XM_066819533.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052593"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8060998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="394" mass="41579" checksum="F3FCC7313FED55EA" modified="2025-10-08" version="1">MADITSTLAPAMSSMAAPPAPTPSAVYTPDPACLDPSNSANYWAVTTSCDLSDIPLGNQYNSSPYPDWLHCTVPMFGAPGYGNPQAASCLAGGPGYPGAAAQGEEPKTYYEGCPVGYAPAAVSSRPGYDVYSYTEGSFDISYYQTTCCPTVYPFQARTLGQGQSTSTSHDGTWYSVYVYPMPECYATSIKALSGGKELPMQTTSNTQQWDKKRRQEETAAAPEPTTTWNYEDGTLYALPQIMAHTVFMGTHTCYEDCSTWMQHYYPDGTGAPGERHTETGERRMPRPSETEGGGENNSPTPTVIATNEGGGSSEESNPVPSPTATATGSGGSGSESGGDDGIEIIEPEDPSDKESPNSQSPDVSLASRIRGGINVGSCSIVALMIPLLVATLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT86</accession>
    <name>A0ABR1UT86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS transporter- SP family- sugar:H+ symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_014243</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660745.1">
        <property type="nucleotide sequence ID" value="XM_066818557.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051617"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF91">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="51"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8062146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="337" mass="36627" checksum="D239024FB2DB6E5E" modified="2025-10-08" version="1">MLGMSTHVTFDHVNVDKNEPEKASSHVDGPSTAETLDYSPLRRLTGRSIAMGALVSMGGLIFGYVVANAQLPRAVRFPQPPNGKLGFSNTRSGLIVGLLSIGTLVGALIAAPVADKIGRRWSICLWTIIVSVGFVIQVAASTVWEQIMAGRLVAGFGVGALSLLVPMYQAETAPPWIRGALVCTYQLFITLGIFLAACFNYGTYTHQQNSSASWRIVIGLGWLWTIMLGLGILLFSETPRFDYRRGRIDEARRTLMRVYGAPANHYAVHLQMEEIGSKLRAESQIKQGAIRGDHHHVPGPAHGVPDRAGHDAPDVPAADGSELLLLLRHRKSPQHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTV1</accession>
    <name>A0ABR1UTV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LPXTG-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660956.1">
        <property type="nucleotide sequence ID" value="XM_066818768.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051828"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8062357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="496" mass="52914" checksum="A16A62214E434BBA" modified="2025-10-08" version="1">MTSLTSVHTFILFFFFYFIRFSITLQVTPNSPCASFCVDSDDLDYSDPNSSNTLNKDVSCHDKDYASTAVGQKFRRCLSCLQDSTFAQGSETDQGWFLYNLRYTFDHCIFGFPNATDTESTPCSTSTACGGLENALTSDKLNVKGGLEPYGFCAADGGAMANAPVIHQCVSCVSASQDQKYLANYMVALQAGCTQQPSPGTAVGLNATVFSPTIIGMVDPISSSAAKPANSPALATPALVGIAIGGAALLLAIAGLIFVRRRTRRNRRQRLAASLDGNAPNRRKEKATPYMSPTAALSSNPVSASPYWSPSIAPSSTFSKAEKEQQRSYGRGGGGGPNLQSIKTGAPTVPDHVHYSTSPKAKGFSPTDTATPASAVSTKSTAQLLPLRAYNPADYSGVTQPHMSAAGMMDYNHNHSPYSNHSANNNNPYASPTSASTASPLLSRAWEQQSLQRTATWDPLPTIPQRAGPNHRLPAVKVLTEEIKVSFAGPPPRRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UV09</accession>
    <name>A0ABR1UV09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661368.1">
        <property type="nucleotide sequence ID" value="XM_066819180.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052240"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045672912" evidence="1">
        <location>
            <begin position="28"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="136" mass="14211" checksum="62329B37681A30C5" modified="2025-10-08" version="1">MLTLASSSVSGVRFLDLFILILPLLQRRPTTPHLPAAFTAGRARRLVQDRVDGETGHFVALDEGAAGTGIGLDGADEWFLVAVDDARAAELVLEIGRDRGRVRVRACRPGAHGPAGRLAGALEHGRAQVGRGAAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVQ3</accession>
    <name>A0ABR1UVQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alcohol acetyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_015095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661597.1">
        <property type="nucleotide sequence ID" value="XM_066819409.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052469"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010828">
        <property type="entry name" value="Atf2/Sli1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07247">
        <property type="entry name" value="AATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="57743" checksum="E2710012B1CCE4A4" modified="2025-10-08" version="1">MAPISQHGADTSVLRKFGINEAYQLAMYILDQYRGTILSCRYEIPSRLASAEAQLEEAVKVAIVDTIMRHPMLQVGMTDATSKSPSWLQLDSLDLTQHIKWIQVGEYDDFETTMQEAFCTQLDDRFPDFSVKLPNWRVTIFRQGHAPSMEVMLTWNHPQFDGAGAKVFHEDFLELLNSTGNGEYAWEGLEANILRLPEASPMLPSPIEDLKKMPVDLKYLSKVFWEEIRPSALNRDKSLATWCPIRTSPYKTQFRSFFIDDASLSAILALCRQNKTTITGLIHGLALLTFSLHLNSKAAPAFQSSTVMDHRRNLPPAPADAPWGSSGRVVGNYVTQAVHKYDTSLVKRIRSKMLPSDAVGEGEGKGKALSADLISELWAVSAKSRRAIEQRLEAGLRNDLVGIFKFVTDWQKTMGDMAKRKRQFSWLVTNIGVMKGGGGNDDIESDHEGIKKSWAISRAQFGLSAEIPAAAIEFSPVSVAGRGMWVGANWADCAVDVTLGERIMADMERWLNQLASQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1P5</accession>
    <name>A0ABR1V1P5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661871.1">
        <property type="nucleotide sequence ID" value="XM_066816179.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049239"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619:SF3">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="644" mass="71863" checksum="5769D225F3E48223" modified="2025-10-08" version="1">MASHLPIVANYPLGNGGVVTAELLESWCRGEGASVHEAYGVETYYSKDQSKFIPGPEPAVVALRQLLVQVGQLQIPTQLDVFNDNQSSHVQTTSLDLLKCSWDDVINQLEAAKVENGKHSKKAKRRIDRAIDSAAPYMEYWIECLPEEYGLSVVKGGLTLLFVTARRKEQNREKIIQVFEEIPGMIRTIDAAYKLFSRDDDEDVAGLAKSFYDQLCEDIPQLVEILNGTKTRFSRMKNRFAGGSLETQTVDSILGRLNQRSSAMKTTIDRIKTKLQAKTSDDLQVIRSRIEDTNMGIAIVSGQLGGLASKDDLERLLQKANGKLALLGTQLIDTVRHEVQSQVKSILKDHSAADHAAEAKTMLLWITQEIAMLRERVATQNLQIEYSHPRQPSPRPIPETPVLSEQDLMHILDVDPRSWTEDLASVLRQASRMDADSKARARWLMKTQHFQRWFGASHSALLLAAGALRLEKVSPMSVFTSSIALNLLEPPDTIMLHFFCGKHLDADAEDHLSGPLGMLRCLIAQLVIAFKAPLPNLNAIGSPQFIHDCYNRTLNALCEVFRLLVEHTPHGVTVFVLIDGVSWYEQGDWTADLNFIIGLFKVLTEPHRLPVFKVLLTSPSRAMEVQNLVDLDSDIVLHGAINAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V250</accession>
    <name>A0ABR1V250_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell surface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662018.1">
        <property type="nucleotide sequence ID" value="XM_066816326.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049386"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF1">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045515734" evidence="1">
        <location>
            <begin position="19"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="296" mass="30053" checksum="EE80474811F0596E" modified="2025-10-08" version="1">MRYSLVLAAAGLVASVSGHGLVTKSLTAHPRDCSSNGCGSQADTAIIRDREIQSGKAGPLGRTQGNGKVEAATMIASFMGGGVAPTNNGTGVGVEDNIPANVGQKSTKNTRGVNSAKFRRQGFLSGLLGGGNNGAAKAKGTQTKTAAETNVKATAGQGASDGLPTADENGEVTLQFRQINQDGAGPLEAMIDGTSGGTDMAAFKKAEVTQDVPGFVAGLSTATMTDFDVKVAMPQGMTCDASVGGADNVCVVRVRNNTPAGPFGGSAAFTQTNAARKRAIAYRIKKRAEEARQSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V262</accession>
    <name>A0ABR1V262_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662036.1">
        <property type="nucleotide sequence ID" value="XM_066816344.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049404"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="128" mass="13358" checksum="732C3AB600C7316A" modified="2025-10-08" version="1">METQRRTAAIQVAIAGLTAVRATTAADPRIRSRRVFISLVKFPGGVLVLVLLLLARRADRRRDARDGTRGEALVEGGGADGQVLLLLLEAALVGLGELGAAEAGVVVVIGAFRHEVVVVLVVAGTAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2E3</accession>
    <name>A0ABR1V2E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">rRNA biogenesis protein RRP36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_012112</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Associates with 90S and pre-40S pre-ribosomal particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
            <location evidence="1 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the RRP36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662118.1">
        <property type="nucleotide sequence ID" value="XM_066816426.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049486"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009292">
        <property type="entry name" value="RRP36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06102">
        <property type="entry name" value="RRP36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 10" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="221"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="298"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="28"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8065365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="326" mass="37492" checksum="F0BE771FD9C6C29F" modified="2025-10-08" version="1">MERSQSSKRKFPFAGLQRRVRARKEEPEIVDDSNPSEEEVSGDEDEDDQSDSQGSGEEDEEDGDDQSDSSEEEEESQSLDPSQISFGALAKAQASMPNRRKNARKDEEEEDSDNSDVSEEDARGGGGFDGKASERKHALQKRSSKHAPMEVSAKRAVTRKREVVSVPKVVARDPRFGPLGTTSSTSYNRHPNPAMEEEATRRNYAFLDKYREDELAELKKEVKKTRDPAAKEKLQRAVMSMQSRKQMLERRDAERAVVTEHRRQEKELVKQGKQPFYLKKSEQKKRVIMDRFAGMKKGQVDKAIERKRKKLASKERREMPMERRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2T1</accession>
    <name>A0ABR1V2T1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662256.1">
        <property type="nucleotide sequence ID" value="XM_066816564.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049624"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF73">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN CTR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0187">Copper transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="73"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="218" mass="23482" checksum="5CC9169C3C3FC938" modified="2025-10-08" version="1">MLWNWNTVGTCFLSEQWQIKSDGGFAGLCIGVIILVIFLEFLRRVAKFYDNHIYRAHQLRAVGMAVDRAGGASSAAEEGQAGHPPGTGRASGPAPSSSGTRSQDASVDERPSSLVPRQSGGVMSQAQPLLAGANPNQPFASAFLPSVKQQAIRALIHTMQFAVGYWIMLMAMYYNGYIIICIIIGAFLGFFLLRWERIGSSSLERPGELSGEATGCHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2W4</accession>
    <name>A0ABR1V2W4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-alkyl-2-acetylglycerophosphocholine esterase</fullName>
            <ecNumber evidence="1">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012280</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.47" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662286.1">
        <property type="nucleotide sequence ID" value="XM_066816594.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049654"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF0">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8065533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="124" mass="13313" checksum="EA14F28F7117AD7A" modified="2025-10-08" version="1" fragment="single">TLTEDTYGKPAFPVVVFSRGLGGSRICYSAVFGELASNGLIVVAMEHHDGSAARSCVNILPSSKLTDGNRIDNTEPRTHYENNAQDNAPQNANGADTELRNAQIVMRMAEIEEAISVLSQMNCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V320</accession>
    <name>A0ABR1V320_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012326</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662332.1">
        <property type="nucleotide sequence ID" value="XM_066816640.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049700"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052649">
        <property type="entry name" value="NCE102-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28165:SF2">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28165">
        <property type="entry name" value="NON-CLASSICAL EXPORT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045043989" description="MARVEL domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="7">
        <location>
            <begin position="7"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="177" mass="18470" checksum="F3666CD764146B28" modified="2025-10-08" version="1">MLSFIAMAVRGLLLLSAAVVLGLSVSNAKYQVFGNPPPETSFGSFTGAFGVLVSLVGLAALFIDKIPTFFVMAADALASIFFLAGGIALTLAMKDVSSCTGGDTLGDYQRATNKLLNGGCTNGGNDVTYCGVGSSPHPLDELHGRCQRVQADYVFEFIGFIFGLVIIALGWVFAQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3Y0</accession>
    <name>A0ABR1V3Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012642</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662648.1">
        <property type="nucleotide sequence ID" value="XM_066816956.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050016"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="342" mass="37096" checksum="320591B092E678B7" modified="2025-10-08" version="1">MTSFDNAVVPRGSVVLITGANGFIASNIADAFLSAGYRVRGTTRDPLKHAWLRELFDTKYGHGPFEFVTVPDIEADGAYDQVIKGVSAVIHTATNPSMDPDPHKVIPGTIASTVNALTAAASEPSVKRFVLTSSSAAALIPKPNTSLTVTADTWNDEVVPIAYRDPPYEPERGYLVYAASKTLGEQAAWKFMREKQPGFVLNAVLPNLTFGASLDPVHQGHPSTSGMLAELFRGNPALLAGLPAQYFVDIQDVALLHVAATINPTVVSERIFAFAEPVNGDGILTILRKMYPDRSFPTDFQSERDLSDVVLRKRAEELLRGMGKNGWTSLEESIRRNTVDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4B8</accession>
    <name>A0ABR1V4B8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-mRNA-splicing factor 18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_012793</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662799.1">
        <property type="nucleotide sequence ID" value="XM_066817107.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050167"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004098">
        <property type="entry name" value="Prp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039979">
        <property type="entry name" value="PRPF18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007:SF19">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02840">
        <property type="entry name" value="Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47938">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="10">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Prp18" evidence="9">
        <location>
            <begin position="203"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="52"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8066046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="350" mass="40571" checksum="1EDD816C107F6A9E" modified="2025-10-08" version="1">MDFASLMSKEIAKAKAPAAEEKSKKYIRRSEAEAQREAAYLAEQKALEEKRALKAAEKRKREEDAAEEALVQTEKRRKLEEETRRRREEATAEEERQRRKRLGLPELRKEDSSEATDAPEDGTEDIPDDELVTKLRELGEPATLFAETHRGQLRRYRKLTTVITRGPIPTTLQLVDEKDMRITDGNIPTDKEARQYLFRQLASYFTMVLREWEAALAREERRDTFESKAAISAMTQSRDNMVPLFRRFEKNELEDDVLKPVIEIVQAAQERRYVDANDGYLRLSIGKAAWPIGVTMVGIHERSAREKLHNGERGHVMGDEVTRKFLQSIKRCLTFAQVRWPPEDVRQLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4G4</accession>
    <name>A0ABR1V4G4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras guanine nucleotide exchange factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012838</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662844.1">
        <property type="nucleotide sequence ID" value="XM_066817152.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050212"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11883">
        <property type="entry name" value="SH3_Sdc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056685">
        <property type="entry name" value="DUF7783"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056686">
        <property type="entry name" value="DUF7784"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057827">
        <property type="entry name" value="WW_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25006">
        <property type="entry name" value="DUF7783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25008">
        <property type="entry name" value="DUF7784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23518">
        <property type="entry name" value="WW_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="70"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="8">
        <location>
            <begin position="804"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="7">
        <location>
            <begin position="973"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="713"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="737"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="758"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1226" mass="136971" checksum="A7D078AA2967A031" modified="2025-10-08" version="1">MLMTVNASPALRQTRTTNTLSLRYQANSDENNPSSAANLSEPASLGTSGGDGNFYKQNNIMNGIMGTAPSGTLYVRALYDYEADDRTSLSFHEGDVIQVITQLESGWWDGVINGVRGWFPSNYCQTITSPDEIPEAMQNGEIGAAEDELEDQGLYEDEYDRDNESDQDDFNGLPLEGTKETVVRSGGADFWIPQATTDGRLFYYNTMTGESSMELPLESPTSFTESGPRDRMNVNMPEKTRPPPEMMARGLTQDEDEDSEVTSSSELEGESSRKPSHSSLHSRGRRGYTHDGVGISPAPSMDSMNGASPMARTRAETYGNNSLMPPGAGQTPMLASATSFTGTSFNLPQAASIPRSFFDDGSTPPLTWNLLVANMKRAIDRYRDTITSNNRAEYVARAEDISDHLRLLLAAGSGTTDNHSGQPSVITTNKALYPHFRDMMSKFSKLVISSHIAAADWPNAESAQKCMQEADGVLLGVFSFVEVARQQRGEDIPRLFPGFVIGSTTGGSWQNNALGGRDPIMSNFLEDEEGSTDPTAILDGKLLERLDEQKRMLVSSIRELEKNLGVSEKVITPFRHEVLGNNVCIAGGRVLEMFKPWISMIESVDLSSLGNNFQNPQLGDFSTYKQSLYDNVSDLILGCQAVAGPLGDEWSEVRGESLESRLEYVRQCARALEQNSSHIGFSLQLLSEQVVIPLPQPFESRIRSDSTFDRQQLQRNETMPYPAHQRSDSRSMGARPTLQTAQSYTEGDTTAPATNNYRKGDLSKVRKILGDDPTPSGAMQQVEETPPFLRLDLEGELSWDLKTSPPSVKGGTLLALVEQLTRHDKLDSSFNNTFLLTYRSFTSAREIFELLVKRFGIQPPEGLSNVDYELWRDRKQKLIRFRVVNIMKSWFDNFWMEESNDESKQLIRDVYAFAKDTIKSTETPGSQPLMAVLDQRLAGKEISSKRMIQTFTNNVPAPIMPKNMKKLKFLDIDVTEFARQLTIIESKLYGKIKPTECLNKTWQKKVGEGDPEPAPNVKALILHSNQMTNWVAEMILAQMDVKKRVVVIKHFVSVADKCRNLNNFSTLTSIISALGTAPIARLKRTWDLVPARVNAVLETMRKLMASTKNFGEYRETLHAANPPCIPFLVCVYLTDLTFIEDGIPSIIKKTNLINFSKRAKTAEVIRDIQQYQNAPYSLQPVPELQDYILSNMQAAGDVHEMYDKSLVVEPREREDEKIVRYVKYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4N6</accession>
    <name>A0ABR1V4N6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">IBR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_012893</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662899.1">
        <property type="nucleotide sequence ID" value="XM_066817207.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050267"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="IBR" evidence="6">
        <location>
            <begin position="130"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="336" mass="38238" checksum="556E9ECD4CFE4597" modified="2025-10-08" version="1">MLSLFRQNQSQHKHNVQSGANNLQNVGSSAEGATDIGNQHGGGMEHPLFRQLVLNRECTICMDTKPLEDFPRRRTTSTCDHLPTACRECIQTSLLAQFEEKAMEHITCLECPEMLAPSDVQTFVPRAKYQTYAEHAMNKTLSSIGQFVWCPFGGCESGQIHSPGAQQPVVLCQSCGRQFCFTHHTSWHREHTCEEWDQFLADDSFRSWTQREEDRENAYDADMAALDRRINEAEYILRESIMSAEEAAKERFEFAEARRRRRRSGQRPEEPGSRNNAAWPARRSSGSWYGAGRWRRARRRFRSCHDPVQVANGLRRRLTAATTSTVHNAAVTGTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4R7</accession>
    <name>A0ABR1V4R7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012924</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662930.1">
        <property type="nucleotide sequence ID" value="XM_066817238.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050298"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="243" mass="27051" checksum="A57D2EF73E64BABC" modified="2025-10-08" version="1">MSTSNKKPTILLLCLGDKWMTSMLDDPQAFGEGIDILLEKAILKRAKTLSGALKYLDQNKPDGILVTDPGVVAPSNREILRRLTAFAQSGGTVVFSFSFASNIRADDMDRLWQESWNLPWTMGNYNRSTFQLNTSALGTSTAPDSDGDIRGQSLLWPEYSQKAVHLDNVARENCWYLPTGESRIESMVFPPDRVTNHSQTPVAFTRAGEGFVGYTGDVNQERGTNLVLLRMFNLDIKPVVEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4Z8</accession>
    <name>A0ABR1V4Z8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013018</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663024.1">
        <property type="nucleotide sequence ID" value="XM_066817332.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050392"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF5">
        <property type="entry name" value="O-METHYLTRANSFERASE ASQN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="195"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="440" mass="49769" checksum="FDC21A064C1026EB" modified="2025-10-08" version="1">MSTNRIVELSSRIAANTTKLNDYLASNNLPAPSFDLNGPTDTLIPKENAELEAARVAVIDDTLELRRLVLGPREYLMSYTHDEVISQQAIVRFRLAQYFPVGSEATFAEIATTCELNETITRQFLRHATVKGIFTEPRRGVVSHNAVSRLLAEDEVIRDWVGASYDDLWQAAAHTCEAISKYLGSEEPNEAASRRGFSVANGMNKSVYEIFAENPERARRFGNAMRSFTEGTGFELSHVVNNYPWVDHANGRMVDVGGSQGFVSIALARQFPTMEFVVQDLPPVVESAKSAVPADVSDRVHFMAHDFLTEQPVKGADVYFFRWILHNWSDKYCIKILRNHIPALKKGAKIVINDNVLPEPAVMSNWQESRLRSMDLTMTEIQNAHERELDDWKQLIHTASPGFKFQWAKQPPGSNLWIMVVEWQGNDAQLCPPFWYHRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7D0</accession>
    <name>A0ABR1V7D0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dihydrodipicolinate synthetase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662923.1">
        <property type="nucleotide sequence ID" value="XM_066817231.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050291"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="411" mass="46601" checksum="A39D12F8F6A50F22" modified="2025-10-08" version="1">MPCNFFTKDGPVELIVQIMSLCDSPSDTESLAATCRSTRAIWLANRPTIVWNVWPQADLALTALVQEAEDRGELPPKDMDPSKLSGSVVLSNPEELESMSRLQALVDKLEVAFCLDTWELKKVSTTPAVYKKCPRLRENVRKAVFRVFISGAVLAGAYIESFHEVKRSGLAQVNDLSLLREFILYNPYVKSEAKVSVFERLALWLVDDILSDTDARRELETKISEKGHMDRRCSSARPCVFKSPGNDDCISRHLIECNVMQMLWVYRHMWKTMNPTAQPFDWKSSNVLGFQSRAKLRSMGAGTSQDDPDKVPIVLFGRFQVEKVAISRILSRRRTLGHLGSPEPYILANINIDNCHPQLEATIDLNQSVMTLLSWAYRFTPPPGSVLHPQRLPLDFAFFDYILRQYAATQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7K6</accession>
    <name>A0ABR1V7K6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663675.1">
        <property type="nucleotide sequence ID" value="XM_066817983.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051043"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="156" mass="17670" checksum="A2928FD7089F1951" modified="2025-10-08" version="1">MGAKIRRSVRCRQLIRAFEAQSQSQWTGTDTATITPEHIAKARKLLALFEQVEGERVAAEGDLGDTNDEEESWPKKWETNPSSLPAFLDLFQKWDMDGDWQSKEQQQEHPPVEHTSRRMQSEMTQIGTISAQDVYRRGPLLRGRSQEATSTGNAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7P6</accession>
    <name>A0ABR1V7P6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013960</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663966.1">
        <property type="nucleotide sequence ID" value="XM_066818274.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051334"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF146">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="41"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8067213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="386" mass="43486" checksum="7D505E699B5A338B" modified="2025-10-08" version="1">MWATGAGPFRPPQNPADPGHGPLIMGLTWTFASLSILAVTVRFYVKVVHSRLRLWWDDWTLLLALLFQMVAQACVTHAYTWGLGQHDRDLTVVPQLIHIQKWVYIGVIPNLLASSVARISAALLLIRLFGRRKWFKWYLIVFTSVQTILILADAAVLWTQSEPIEGLWNPFVKAVRRPPSVSESLVYTIQAMLTFSDLTYVLFPIIFVYKLHMPFQRKLGLILLLMLSLVTMTVSLLKTIQAKISVGDGRNTDDMQYRTSLLQVWAGVEQSLVITLSCVPTLRTWFNNTVLPAFQGMTSSVVRVFASYSRSRSIPKGSKGGNDKSNSVQYYDLECQPQMHQHHVSVEGTGYHQSLVPGSQIRQTNNITISTVPIMPEPPPNARLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V839</accession>
    <name>A0ABR1V839_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664118.1">
        <property type="nucleotide sequence ID" value="XM_066818426.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051486"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="228" mass="23974" checksum="A8C1C41E9388F609" modified="2025-10-08" version="1">MTNSYKITVINNTGGPQDYAFFSATPVVSGGFSGPIWSNVLKSAGHTPNGAQASFEVLTTYYATCGSFEGSPEHGGKVTISKSVPINLGSKAGGNVTPGSSVARRATLAPPTTPGQGKLGNFQPDTACKPENRFTMQDAHENNLLVGIATSGGGSITKAMASFAPYPNVKYQIMPPAVYHVGAGSRFQVGDLVKAEMMSNTLAVDFNQRGTNNVTLVHGDDMQFYFHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8N8</accession>
    <name>A0ABR1V8N8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663388.1">
        <property type="nucleotide sequence ID" value="XM_066817696.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050756"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="72"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="639" mass="72242" checksum="684ADC734A83DC3A" modified="2025-10-08" version="1">MDWHSTDCKRPDIVDFGNGRSCLACGSIEPRSILSPIRQQSEIRILRLQHGAFDDPIVCEVCTKDLTFYPEYEAVSYTWADESGDATRSRTIQIGDKPYQVTVNCENALRRLRRQFSYRKLWIDAICIDQDNLEERGHQVQLMPRIYSGAKAVQIYVGELTPQSHHFLQGLVSQSYGDEVGNGNVYDFHQGMFEFVSRRYFSRAWIMQEVALARQATVICGNISVPWTLVKSGEIASLVRSGLYADSARQSIPPCFAFDHSLYSTPGQELRLLDFAARNCIATDPRDKIFSLLGVIPGGRLGTIEADYSLTASQLYAKTAHYLASQHGWMSVLCRAGVENAFLTEIPSWAPDWTRPLRKDPTMLKGLPMQSFEKGEWDEITNTLTLKFIRHPAWRPREWEAGLLIHEEHLVGGAKNLVFPCDANASTWGIVEALAGDFRLACQDTTAEKDLTLMLKNAGEDYYGLPQVPVHYAKLRCRPAGADSYTLEASNCSDKPVFWSYMPARIAVQVFTMTITEMHYSRILGLFSGTEIDQSLPTEENVNNTMVDLLHRVQALRHQEPTDAELENLWMNEYRAGNLVRIEALQNSSARLQTPLNEPNPGGEGPNSVHHPEFVRINDGVWRLLVRNYILQETTIKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V973</accession>
    <name>A0ABR1V973_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_013260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663266.1">
        <property type="nucleotide sequence ID" value="XM_066817574.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050634"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05225">
        <property type="entry name" value="HTH_psq"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="4">
        <location>
            <begin position="141"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8066513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="251" mass="27503" checksum="3CA75FE338D4B4D3" modified="2025-10-08" version="1">MEADLEGSPEAPAEKAPAEPSPSTPTSKRRYRSYNAEDVQRAIQAVRHDGMSLRKAAILFNVPKTSLADRLGEDRPSPPPLISHQPGGRGRVYTRFTWTEDDVAKAMLAIEAGTGTSQAAKQFGVPFTILNARIRGHKPRVLKKETAKLTMNQEQLLAQWAGAQCELGFPPSKEEIYDLANRVMQKNGAGKSLGRQWVAHWLRRNAHIRVRGAESAESQDSLFTTAVFEAPIQATADVHGDAEDITDPPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VAL1</accession>
    <name>A0ABR1VAL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663822.1">
        <property type="nucleotide sequence ID" value="XM_066818130.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051190"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045640548" evidence="1">
        <location>
            <begin position="22"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="375" mass="40973" checksum="5D2306692D34136D" modified="2025-10-08" version="1">MGVKDFLRACALAALGAVALSKPVYTHRRAAFFEAQKLADPAYGPVPGQDPIFNTYWGKAPTWPGNLTDPVLPTKKGPPGVDDQVWQNLLAAEWIIFNFYQQAVEMFNETSFIAAGMPNTTYQRVKEIRNNEAGHLRIFQNQISETSIKPGACKYHFPYYDPVSFLALGTVLEISSMAFLTGLVQQVKLDKAKGAMLTIAETETRHEVWALMDIWKVNPLGGPSDTVFPYANEVLGSTSNLVVAGSCPKENPEYPYPNQRLPALSASKNTTSFVPGATIDLAFSDPKNQPKFVPGKQYYAVFFHGLKNITVPIDTCDWPKKSINVTIPAKFEQKGVIATVIADTPGAPTKDTIVAGPGIILEQPEPLGVKLAQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGQ6</accession>
    <name>A0ABR1VGQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664231.1">
        <property type="nucleotide sequence ID" value="XM_066814941.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048001"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF37">
        <property type="entry name" value="AMIDASE C869.01-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="521" mass="55306" checksum="9A7470ACED27D5A2" modified="2025-10-08" version="1">MPQCGGFQLEEATIDQMQAAMENGTLTSVQLVTCYMMRTYQTQEYANSLLQLNPDALAIAAARDAERQAGLVKGPLHGIPFTVKDNIASKDKLETTAGSWALLGSVVPRDAHVVARLRDAGAVLFGKATLSEWADMRSNNYSEGYSARGGQARSAYNLTVNPGGSSSGSAIGVTINAIAFSIGTETDGSIINPAERNAIVGFKPTVGLTSRAGVIPESEHQDSVGTFGRTVRDAVYALDAIYGEDARDNYTLAQRGKTPPKGGYAQFLAKSDALKDATFGLPWHSFWVHADEEQQTALRSLLSLIESAGATIVNGTEVAGYERLVDPNGWNWDYGSARGFPNESEYTVVKVDFYNNIQTYLAELSNTAIRSLGDVVQYNYDNDGSEGGRPWPAGGNPAFYSGQDGFLASLATRGVRDETYWQALAFTQSATRAGIDAALTCRGGGQRLSGLLVPPDVGQTYQIAAQAGYPMLTIPAGVRSSSSSSGGGGGGSGMPFGLALMQTAWGRRNWCGGRARSRTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHH6</accession>
    <name>A0ABR1VHH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664489.1">
        <property type="nucleotide sequence ID" value="XM_066815199.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048259"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="33"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="258" mass="29057" checksum="CFF08554495B82D6" modified="2025-10-08" version="1">MVVPQAEDPSTMMEESGSRLFQNDLFLMQSSSKAFTGNFKEASTSEVIIEGHATQAVYGVLHYLYTGTVAQEDFTTVRSALDLFIAADYFNIAYARDEAVEIFGIQLRYLSRLNHSSGLENELLPTEDRDSFFLAARFAYTSVPNFEVLRPPIERLIQQTDFLLTKDTRFMQELKSIPEFAVVIIEMMTSRVANDAISRWPAIPQSCHGCGRGETKFADIWVASVRDMPGRYSKHHLKLRGNCDDCTAALGDKRSTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHH7</accession>
    <name>A0ABR1VHH7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664502.1">
        <property type="nucleotide sequence ID" value="XM_066815212.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048272"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="178" mass="19950" checksum="6E919B80930D4220" modified="2025-10-08" version="1">MGFIDITHDQPHRVNKLSIWVHDLRKDASVAPSSSTLEANDSSDSSPHTTSTVASKPRIQPLFRPLNDSELALLKRDPDTALWPTPKWIVGSWLSQSISEITNNLQDAVGHLTGCAPVTPILLEEKGRENVAKRNPYPFPLPLNMELDEEYRADRIMKGWGSPSQNLRGEPQHWNAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ98</accession>
    <name>A0ABR1VJ98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665112.1">
        <property type="nucleotide sequence ID" value="XM_066815822.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048882"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF5">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="319" mass="34709" checksum="8000C32C8D8B3807" modified="2025-10-08" version="1">MSPLRMSRMYRPADTATTAPRIELTPMPQLAEATNKKDDWTGTTDAASRRRAQTRLNTRAYRKKTEGFSKESRKGVQCHVRDIHQTRTTGGMLGYGAAVRFHGSSVPYQTAVQCANSLIPGTNSDRQQQYNNIAFPLSPDHLITLLQYNVLRALSVNRTLISGILTTPLDCSEETIHVLSYRPSSNSQSLLPPSLLPTTLQQTVPHGDWVDIFPCPAARDRVIRAAGTFDEDELWADCIGGAVRGLSRRRGGAARRRCVVAAVGRFGVGDVGGVRAEVGVVICYRRHGAGDAGGDESVAEGEGEEALWYDIICASPNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VL95</accession>
    <name>A0ABR1VL95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SNF2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_011279</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664884.1">
        <property type="nucleotide sequence ID" value="XM_066815594.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048654"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF26">
        <property type="entry name" value="FAMILY HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SNF2 N-terminal" evidence="5">
        <location>
            <begin position="23"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="968"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1036"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1108"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="386"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="975"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1060"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1149"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1193"/>
            <end position="1205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8071076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1205" mass="134694" checksum="EB57DEFC0D9D66F1" modified="2025-10-08" version="1">MEEDYVDGIHTRVVGYASRMVVRRGGIVADDIGYGKTVMVLAILNLQKQFDQDQYQLRQKDATNGIEALDCNLVICPTHIVNQWGEEINKFLGYRNGHEFALIKTWRDLKNTNLKSHNILVLSDGLFADIQYSKAVETCAGMEYPAAHLTPKQLREWKDGRGYWEWYEAAVKKIESKTVKEHSLLQRYSFNRIVWDEVSYSNPTVSAFVSNCRAISKWLLSGTPPTQSLRDVCSMARTIGLHIARPIDLRPGLPIMAKGPAQMPRTGFEEMDSWEPLKTTASITERHCQGESFFNAFSVCNMIDPKSREFKVMEWALVVPSTLTEVSTYLPLQDDLRQADMDAESLTGDGSKALKRILENAGEPLDGENACATALSHVATAPSLATDPSSLRGSSHSVTSYHQRALKKREDTMKEARAYAQYSFERLIWLATRLYRTLHRITPPSNKAIAKMTDDQKKAAAAQKKAAKDDANDYLTTTRGLSVFLKDFNNGTPARFKGRHNYAELAKAILRADPRQIDAKISNEEALLGLHEIKNSSGRLMGPFMTCDENVNLLYKFFNSKWAKFYLLDVTDVRDTGKIPREDVINLLLPYDECSIKQLEAQTETTLRSKLEAIVKGRLQERVDELAENQQEYERTHADETGDLPVILRREGVKVGSTKSKGQLIQAYDDHKKKALGMGGYNTPREAACYASATMPFVEEKVRARGSTKWQTKDEYYSAWNAFLKACRYLYEQSAQLRRAKLFCDLDAGAATACDVKRLQHADRLPGTDAGVIQLSRFTDVQDRQIKATHLPSSGGGRTSAYWKLDSKLRYVIDLIQATAVDEQVVLFAQHQVILRKAVEALNQCHITNTTTNAEVAGDRDNYGEDPLGDFKAGKYKVLVMKVNSAEAAGGNLTVANHVIFLSPVIGNSQPLYDSHMNQAAGRCIRHGQNKNVHVYHCVTEGTIEVDILELRKHKEVRVQPGLALGGLVPRRSREHSDQDDAAEVAKDGDEKPHWVDDSEGKPEAVRSVLSSHEVWKGLSETDLALIMDIEDPRADSTGAYMHKNPKNPNDLENPKAPETSETPSDNTSSPGEDSVAAIHALDQFAGLSISDRAVIESQYNDICARYQWPQDNSQGNDEGYPGDDGGNGPPDNDGDDEEAEAMNVDSQAYEEPESMAVDSDEDEIIDRRVRHRRHRRPDIMDVESGDEAAHATGKRPKPVVHKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLM3</accession>
    <name>A0ABR1VLM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664566.1">
        <property type="nucleotide sequence ID" value="XM_066815276.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048336"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF6">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="522"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="757" mass="84361" checksum="79AAAD32817D7C8F" modified="2025-10-08" version="1">MQFQQDGKTLFLRGVNLADAKFPPGRPTYLRESLDNAESCSYIGAPLRIEDAPEHLTRLRYLGYNVLRLPVPWEALEHAGPGKYDDEYIEYVRQLVEICNEHGFRRRPLWTLHACGLNPDKFGETHAAIRYCEWPLDEPDPAKKDPKSIPPMMWTTNHNRLVSCTVFALFFGGRDFAPRCTIKADDGADVNIQDYLQSHYYAAYARLAERLGDLPFGFDGMNEPEPGYIGWQDLDINEREHTAKIHSNPTPIQAMRLAMGREQREVHEFRLGQTGPHKTGTMHIKPTEGASCWLKQEDPRWPFRRGESWPLGMCVWALHGVWDVETGDLKRPDYFANLPHTSEAATKKENSADSVEFTFVESYWREFHRQWTESVVRAHSSKTVSFMQPCVFSPLPAPSPPQSAGSNAHPNSLNDQTGEKLDKKEQMSLLAYSPHFYDGLTVMRRHWHESWNADVVGLIRGHYKFKAFGLRVGKGKVRKVISDQIGRLALDGQEQGVPTLIGETGIPFNLDDAKAYRLSRPGSASSATSGASITSGDKNKKSNGELDGKKEEEEGSEDGESGGGGGDYTAHVKAMDALVSACDDHLVNFTLWAYSAVNTHEWGDGWNGEDLSLYCAETGSFPNHPYLSGARAPAAWCRPFMQSLVPASASSAKLVRMAFDLKTSRFEAEVDIVGGQQDGEAVASIYVPWLHYRQGNEAEQLALQVQVAEGDAWEVQGQVLTWRIRGGGGGRKKFEMERQGGGVVAAGAGHDCGVRWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTE8</accession>
    <name>A0ABR1VTE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665453.1">
        <property type="nucleotide sequence ID" value="XM_066813491.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046551"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="322" mass="36045" checksum="8964EFFF5B93168C" modified="2025-10-08" version="1">MDRNPASGKPCASEHTRTRAEASGSRSVPPPEDREMVEARAQYLALRKEILPESDIQQRQARARHRLYTTVLDGNLTCCKLPSRVNRVLDLGSGIGCWAVDIARQHPEASVTCVDHHPVHLQDAPSNVTFHVADLNRDWPVEPNSLDLIHIRAMSDDVVSWPFILSQALKTLRPGGQLEVSEIRPRFWDFDGLFAVTDALPEGEQMSAELSAKMGVDLDPSANLPMWLDDAGFEKAAQRSEILPVGNWSKDAKLHQRATVYKDLLELSGWEGKSRQLFVSSGWDLPRYTALVNRMKESITHGGVRVYMTAVFTTCRRPADEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTW6</accession>
    <name>A0ABR1VTW6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665618.1">
        <property type="nucleotide sequence ID" value="XM_066813656.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046716"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="119" mass="12915" checksum="B397673B6274833E" modified="2025-10-08" version="1">MSPMDNTQTSGISEPTSRRRPSTLAGPEGPIARPRRIHIHKSLARTVDWELYDRRAEREARRYTDEEVLVSLSTRNALALHGTLTSPLLSPASSTASDSSSSSRSSTSTTATTPSFSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUF5</accession>
    <name>A0ABR1VUF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U6 snRNA phosphodiesterase 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3'-5' RNA exonuclease USB1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009536</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665813.1">
        <property type="nucleotide sequence ID" value="XM_066813851.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046911"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027521">
        <property type="entry name" value="Usb1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13522">
        <property type="entry name" value="U6 SNRNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13522:SF3">
        <property type="entry name" value="U6 SNRNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09749">
        <property type="entry name" value="HVSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8074873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="131" mass="14479" checksum="71D55BE58A22DC97" modified="2025-10-08" version="1">MALLVDYSSSESDAAASDTEPEAKKRKLQAPSPSTATTGQDKPKKTTGTANTTNSSVTTFHDLYASTVRVSTRDDPTLHQGRKRQNPHVAGHWPSHLYTEWHPHDHGHLPRVRDPDRSPGRALIFRLCCSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUU3</accession>
    <name>A0ABR1VUU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CBF1-interacting co-repressor CIR N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009650</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665927.1">
        <property type="nucleotide sequence ID" value="XM_066813965.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047025"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022209">
        <property type="entry name" value="CWC25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051376">
        <property type="entry name" value="CWC25_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12542">
        <property type="entry name" value="CWC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="9">
        <location>
            <begin position="11"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8074987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="290" mass="32243" checksum="80462FBD665BD295" modified="2025-10-08" version="1">MGGGDLNLKKSWHPGLMKNQARVYDEEKKALEERKRTEQRIRELKEERAKEEIQNQLEAAGNRKRVDRVDWMYSGPSDTGGGTAEELESYLLGKRRVDNLIKGTDHQKLEKNAGEESFMALQNANTARDTAAKIRDDPLLAMKKQEQAAYEAIMKDPTRRRIENIVATDTTAQIRGPAMIPGTESEGIGATDLTQETPLHVRAVRGLRDRTRTNIGRGGTAPKNAHLKGQDGMIQIAGIPMTEDPKRLSGTMPSVAGATVLDIKTRQTMEIGMRMAAVRMPRLSKNERGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWG0</accession>
    <name>A0ABR1VWG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666127.1">
        <property type="nucleotide sequence ID" value="XM_066814165.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047225"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015904">
        <property type="entry name" value="Sulphide_quinone_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632:SF2">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="37"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="445" mass="48255" checksum="D3C7D5EDDAB196E5" modified="2025-10-08" version="1">MFSRSTARAARTARQLVSGSRGLASVSPVTSAARSHKVVVVGGGTAGLSISHQLLNSGKFSQDDIAVIDPAQFHHYQPGWTLVGGGLKTMEELRRPMNSLIDPKLKFYSDSVGAFAPESNSLTLGNGDSLTYQQLVVAPGIKINYDSVKGLPEALADPSSLVSTIYGQDNCSKVYSTIQKLKKGNAIFTQPAGVIKCAGAPQKIMWLGLDTWKRAGLYDPSNPSNSPIKISFATGLPVMFGVPKYSAELDQLRKERGVEGLFQHDLVSIDGDKAVFANGQEKVTKQFDLLHVTPKMGPHAFVKNSALANEAGYVDVDDATTRHKKFPNVWSAGDASSLPTSKTAAAITAEAPVLVRNLLLSMEGKDVDASYDGYTSCPLLTEYGKVLLAEFKYGGVPKETFGKWIGMDQKTPNRFFYHLKKDFFPWVYYNNMVKGTWGGPKGWTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWQ4</accession>
    <name>A0ABR1VWQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666631.1">
        <property type="nucleotide sequence ID" value="XM_066814669.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047729"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="387" mass="39040" checksum="50BD909A85A53043" modified="2025-10-08" version="1">MPSPSVVGASRILGYAAMLAQASLGAAGPLPGAVGEREVACDANNSLLKEFRVTSHTAEASSFCSKYVHAEPTAMAAAAGTVSIAAHPMKFYSMEAYQADAAPLTYGSPPTASPVPGSPGCFGHSGDTPCAVSQQKRSMPTAPPMLRDLPLVQESSSSAAAPALPSFVDSAYPPTSVSNACSCLLSSSSPSSTQPAVAAAAATSTGASAACTTVTGSYPATTVPAFCNPALHTNAPSLANPNNMPVATMTVGAVSNKVDCCSSCAGIFNCVAWQFVPAYTGEPSEKLPGGFDPWGRGDCQVVYHTGAPDEAKNVTTNDALAVCPNGKVHEMLSGSNNPPVADGASTEQWNNVYFNGWNQGSCGMPLNAGQSGDSPGMGDKSNLCPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W073</accession>
    <name>A0ABR1W073_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_010478</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666755.1">
        <property type="nucleotide sequence ID" value="XM_066814793.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047853"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF115">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="319" mass="33360" checksum="7AE171455BA53AA8" modified="2025-10-08" version="1">MSQDFGQRSVTTRDDEIGEVLQTVPTARTDLTGRVLPQMTLGDGNMPGSLVAPPPPLPRSASPASRAAARFRVEGNAIVTGGAGDLGQAASRALLEHGLRGLMLFDLNAGDAAAKAESLQAEFPQATVRFTKVDVTDALAVNAAVAETAKQLGSVDALVALAGMVGCQHAVDTSPNEWNRVLSVNTTGVFLCAQAAAKQMVKQGTGGSMTFIASISAHRVNYPQPQVSYNVSKAGVMAMVKSLAAEWAVHGIRVNSVSPGYMDTILNEGSGSTRRRIRNPMRRMGQPDELTGVIVLLTSRAGSYINGADILVDGGQTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W0B5</accession>
    <name>A0ABR1W0B5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666800.1">
        <property type="nucleotide sequence ID" value="XM_066814838.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047898"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF50">
        <property type="entry name" value="UPF0659 PROTEIN YMR090W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="10"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="258" mass="27688" checksum="1F58D8DAD3115ADC" modified="2025-10-08" version="1">MASPHVLLLGGSGKIAQLLTPMLLQRSWAVTSVIRNPDQVAGLEKLGEGQKGKLNVLVRSVEDVKSEDQAKSILDEVKPSYVVWSAGAGGKGPPERTFAVDRDAATYFIRASAATPSITKFVMISFLGSRLADAPWWTEDMKQQQQQMKSGPWPAKVAADQVLYEEGKKRGPGFAAICLRPGTLGETPVGKVSLGKTDKYGGVKASRVSVAHLTALLLENKDVKSCWLDMLDGDEDPAAAVDRCVKDGVDCAVGEPFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W0E0</accession>
    <name>A0ABR1W0E0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1776-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666589.1">
        <property type="nucleotide sequence ID" value="XM_066814627.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047687"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013952">
        <property type="entry name" value="DUF1776_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF1">
        <property type="entry name" value="3BETA-HYDROXYSTEROID DEHYDROGENASE DHS-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08643">
        <property type="entry name" value="DUF1776"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="52989" checksum="DF763EB9BC938A57" modified="2025-10-08" version="1">MDTRILAPEGPGPGAAPIEVVHMSTIERMQDWVVRHKILTGVMVFTVGYVTYKAVRKTKHMRKSRRAKRARNGGRLEVVVIAGSPSLPLTKSLSLDLERRGFIVYIVCSTIEDELMVQHLSRPDIKPLNIDITDVSLLLYSPTTERRRLYRTLRNILADTTLGCSPNESELPDVEVRHPHTFAQLPNIADRHHSAILICGPLQHPPAASHSDDPVFPAAPDVAPDAPGSEKEAAAAAAAAAAAASNSKKDSTTDNGPTTPKVLVFTPSIISSINPPFHAPEATVCSALSAFTEVLTGELRPLAIPVTHIQLGSFDLAGFVPQTATTSVGATGSGTVRHHAHHAGLLPPSAETLTWPESARHAYGKNFMSQSSSAISAGRIRGLRGSSLRELHNAVFDVIDGSDQRPLVRVGLGAGLYGFVGRWVPKGLVAWMMGIRKVDELSMWGNGSYTTGESRSSETDGEDGGSSSGGSENGEGSEFIAVGHDHDGASNVWKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7B1</accession>
    <name>A0ABR1W7B1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007193</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666850.1">
        <property type="nucleotide sequence ID" value="XM_066811508.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044568"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="95" mass="10462" checksum="FE0B05B6888CFAFB" modified="2025-10-08" version="1">MESFSAFSIGPRNCVGKPLVYLETSIVLAKTLWYFDFEAAAGPLGAVGEGRDRGRPGEFCTWDVFNSTHDGPYLVFHPRGSAVLYEDLKPRSMGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W881</accession>
    <name>A0ABR1W881_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667165.1">
        <property type="nucleotide sequence ID" value="XM_066811823.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044883"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019182">
        <property type="entry name" value="Cytochrome_b-c1_su10_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254:SF1">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09796">
        <property type="entry name" value="QCR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8079690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="56" mass="6084" checksum="727985C97D22B8B7" modified="2025-10-08" version="1">MFTQLGMKAGAFGGVALFAVIFYASGIPRVQNDVLMKIPGLRSYYVKDIPASDNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8K0</accession>
    <name>A0ABR1W8K0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Clr5 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667284.1">
        <property type="nucleotide sequence ID" value="XM_066811942.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045002"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="17"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="239" mass="27372" checksum="536FBFDE2D0BADD0" modified="2025-10-08" version="1">MAEPALLHSTLKRPVCREDWEEQYAHIRRLWWDEDESLERVMSFMEKCHHFQATAKQYKTMLKEWNLLKNVPTNEMKAIVKIQTRRRPKDTEFMVRGRVVPQNKIDRFVKRTMGTAKASPSALSPMSHTPFAVWYVTPLPSPHRDVSKPFLGFTPGNSPKSDAWFSEWVELPPDSLPKAASPPQTGLVETTGLPIPPRASTSAPIKTDRLPHDGHGLHLDANRDLPGSWSKVEQSYNVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8T1</accession>
    <name>A0ABR1W8T1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">EVI5-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_007710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667367.1">
        <property type="nucleotide sequence ID" value="XM_066812025.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045085"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="313"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="648"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="747"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="837"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="897"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1032"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="555"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="702"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="954"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="648"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="662"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="838"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="914"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1041"/>
            <end position="1051"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8079892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1051" mass="114719" checksum="7DED94CF8497D596" modified="2025-10-08" version="1">MDADPVKRQTMEAVSPPTPPTPSSPDTKAHEVLPSTKPESRPVTMIQSPTEKEKPVWPGHDSMVTVRLSEPPTLSVTTDFSALNTMPPRRSLFGPEYAPTPTSAISTQLREEDTIHEEDEEEEEEEEEEQKSGNDNGELSPKITASGSKNLLQELNDSAENDEAQDEETLDEESTEAKDNQTERRASIGSDTDEEEVNWDELQKKEDEQSQDQDDNSTAMLLARLEEENNKLATNPKGIKVKVVEQPTTRRPRPPSMAQLRDMVHGPTPVALRYSVLPPPPMTELEFYMALVKDYQQTAARLPTLLSKKIRQGIPPPLRGVVWQSMAGARDSGLLEQYERLGGESSPYEGLIGKDLGRSFPGVDMFRDPEGDGQRMLGRVLKCFSLYDQKIGYCQGLAFLVGPLLMHMPDNQAFCVLVRLMDQYDLRSCFLPDLSGLHVRIYQFRELLRQNLPTLSAHLDDLQVDPAYVSQWFLSFFAVTCPLPMLFRIYDVIFAEGASETIMRVALSLMRKNDSRILACSELEDVMQLLLSRGLWDCYHYNADEFVEDFVSLSNVVSREKLAQLEQDYREAQIATANAARTSDVTTAASRFLGRLWATSTISTPKSALSLGALSPGLIASSRPMSMLRRSTSKQSLASTLNSMDASSASVLSTASTDATTISRDSSTADDTSVRESTPVAPKQSIGANSRATESRALHTQIEDLLTALSDLQRNHALLATELQREREQREEERLAVKSLLDGLKKSGVGAEPAAEADQPKEEDNDASIDLSKLIDGVQERIAEGEGSNNQTSGNETRAQLRDELARAKELLMNEVAKSQDLNRRIDEVGQEALSLKDQLRDSHTRARSLHQDKQRLEKQVHTMRVSRSSADVQSGAGADAGGWLASAANLAAGVTGTTAPANGGLRELKLGRSKSTPTSQGGLSNRSSSLVRTQTEPIAHTPHNEHDALLLELVQAKTAEAVARQEADEYKQKLESFKKAYGIAPGETPGAASAAATAAMGMFGRLTGAVPEGNSSGTKSAASTPAAAAAASTAAQPATNGGGGFWGWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W908</accession>
    <name>A0ABR1W908_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dolichyl-phosphate beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_007793</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-glucose = a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + UDP</text>
            <dbReference type="Rhea" id="RHEA:15401"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:15402"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.117" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667450.1">
        <property type="nucleotide sequence ID" value="XM_066812108.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045168"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859:SF91">
        <property type="entry name" value="DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859">
        <property type="entry name" value="GLYCOSYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="15">
        <location>
            <begin position="200"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8079975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="439" mass="48215" checksum="078C312797121402" modified="2025-10-08" version="1">MDDALSLIVRAVGATPVPLLILAFAALLVTAFYTVSVTPSNWQVSTNPNKQSPQIYAVLHFVAPKPRAVLSSEKTYKTTTPDGKVVTRQLPCWHDRWLAERHASENRATQEADGPLLPIPDTGSIEPAEIRLSVVIPAYNEEKRILPALEDAVKYLDAHFGRESQRAAADNGDKEKKKGVPSPTSPRWHHRIPPEQALAGYEIIIVNDGSRDRTEEVVLDFARRHALHDVLRLVTLERNRGKGGGVTHGLRHARGEFALFADADGASKFSDLGKLIEGCEDVTDAGHRGVAIGSRGHLVGSEAVVKRSALRNFLMRGFHFILMILTPPATSRIRDTQCGFKLFSRQALPHIVPYMHAEGWIFDIEMLMLAESAPAVPVLSSEGAVIGSSPGIKVAEVPIDWHEVDGSKLNVIQDSVRMAVGLAVLRASWMMGVYRRRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9D9</accession>
    <name>A0ABR1W9D9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U2 small nuclear ribonucleoprotein A'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007928</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the U2 small nuclear ribonucleoprotein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667585.1">
        <property type="nucleotide sequence ID" value="XM_066812243.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045303"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044640">
        <property type="entry name" value="RU2A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552:SF6">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="248" mass="27863" checksum="BC9BA2AA26CD8EF2" modified="2025-10-08" version="1">MRLTVELLQNSPSWLNALKERELDLRGHRIPAIENLGVAGPQDAIDLVDNDIQVLGNFPLSPRIRMLLLARNRIASIQPTLANSIPNLTVLQLESNNLNELADLDPLGTFANLTHLVLRDNPVTKKEHYRYWVLWRCPCVRFLDYEKVKLAERTQATTLFGTAEEPTELASKLMGIKSKTFDVSSASNGPSGDLSTRMSRIKLTDQEKKRLQDLIKKATSLDEITRLETMLREGRLPAGVHAGDAMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA37</accession>
    <name>A0ABR1WA37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histidinol-phosphate transaminase</fullName>
            <ecNumber evidence="4">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_007715</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667372.1">
        <property type="nucleotide sequence ID" value="XM_066812030.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045090"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885:SF2">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="12">
        <location>
            <begin position="34"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8079897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="425" mass="45716" checksum="BE2C98FF8B970F50" modified="2025-10-08" version="1">MSPFNLQTCARANILALEPYRCARDDYKDDGTNVLLDANENAYGPSLPKAAAEKASSSSIGSKGPEIDLLGLHRYPDPHQHDLKQLLCNLRNTHHHTPKTITPENLFVGVGSDEAIDGLLRCFCVPARDRILVCPPTYGMYSVSAQVNDVGLVKVPLLPAPAFGIDIDAVTFALSNEKDIKLVYFCSPGNPTGSLLAKEDVRRILEHPTWNGVVVLDEAYIDFSPDGASMAEWVAEWPNLVVLQTLSKAFGLAGIRLGAAFASAPIARLLNSLKAPYNISSPTSALASYAVSAEGVATMRGNLEKLVAQRNRLIQELPKITGVGRLRGGTESNFLLYEILNAKGEADNVTALAVYETLAENKGVVVRFRGKEHGCLGCLRITVGTEDEVTRFLAAIEKTLIEIHAKQDGAPADEAKEAEASGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBD5</accession>
    <name>A0ABR1WBD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_007593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667250.1">
        <property type="nucleotide sequence ID" value="XM_066811908.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044968"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024884">
        <property type="entry name" value="NAPE-PLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032:SF4">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038896">
        <property type="entry name" value="NAPE-PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="149"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8079775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="485" mass="53557" checksum="6F869E8BCC4F862A" modified="2025-10-08" version="1">MRFLFRHLPRRGFQAPRDPKTATKRASVAFAGAAVIPMAAYSTNVTKPSSLSPTPEDVDAKAHHVKNRRGETTKFTNPHASCNEPSPFQMFRWMIEHRLSGGRMLADTTGMQLNVVKPELLPSRTGSDRLRATWLGHACYYVEFPSGLRVLFDPVFEDCCAPFQWLPPKRFTPPPCDVSALPHIDAVVVSHSHYDHLSYPTVKSIQNSHPDAHFFVGLGLAKWFHQSGIENVTEMDWWQNVELTLTPKSSSPVPNTDEKAKGAATPAAPSPSPATASSTTPPPAPITARFSCLPCQHRSGRGILDQMSTLWCSWAVSSGLTPETSKSVWFGGDTGYRSVPKVPEGADDYGPEYAALPVSPQFGQIGTLRGPFDLGLIPIGAYAPRHIFSHMHCNPHDAVEIFRDTKCKRAMAIHHGTWALTAEDVKEPPRLLREALKRRGIAEEGVFDTCDPGRRGSFERRAMVDGAKLIRIGHCTYVRYVFSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBR3</accession>
    <name>A0ABR1WBR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cdc73 family RNA pol II accessory factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC73 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667927.1">
        <property type="nucleotide sequence ID" value="XM_066812585.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045645"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11990">
        <property type="entry name" value="RNA polymerase II accessory factor, Cdc73 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007852">
        <property type="entry name" value="Cdc73/Parafibromin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031336">
        <property type="entry name" value="CDC73_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038103">
        <property type="entry name" value="CDC73_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466">
        <property type="entry name" value="CDC73 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466:SF8">
        <property type="entry name" value="PARAFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05179">
        <property type="entry name" value="CDC73_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Cell division control protein 73 C-terminal" evidence="5">
        <location>
            <begin position="230"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="412" mass="45405" checksum="59C1C19241F673AD" modified="2025-10-08" version="1">MATTEMDPLLLLRQSFASGSAITATLDDGSEADLSKATKLTFTTPSRISLPIDTATRFVSNDTPVDLRSIYLAWLKREVAIPEYTASVSQLNDELAGGKKVQNLAFVERLDLITWLEGASEESEYIKPLAGDKDGVASNAAAALASKGAQAPAIGGTVGRAGKGTLDPRLAVIYNSERKMGDRNAALRGIKPTDFSHVRKLAAPFMSKSRSSTTNISSNPSLALNQKTKRPDPIILLSPSASSLLRMSNIKSFLEGGQFMPADSANAGSTSSASMLHINRYCKDIDPNRPMRFILVEGPEKFKEEYWNRVVAVFTTGQPWQFKQYRWTNPHDLFRHIPGIYVGWRGDQLPENIQAWGHRVLNVGIDPWKAINPTGTDASRWRDREVVESIWRAIETSMRSKGWKKDQAPIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDU1</accession>
    <name>A0ABR1WDU1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008479</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668136.1">
        <property type="nucleotide sequence ID" value="XM_066812794.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045854"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24073">
        <property type="entry name" value="DRAB5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="148"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="294"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="317" mass="34261" checksum="D9AD9EFA9095578B" modified="2025-10-08" version="1">MSSLEAKIVVLGSQGVGKTSLVMRFCKGNFNPSQVTSTVGASFMAKRVIDSDTDTVVRLQIWDTAGQERFRSISRLYYRGANACILCYSITDAQSFAEMGVWLTELRRNLPPDIVLHVVGTKADIVAKEPARREVPFERCIAYVAENLAPGQGNTPPPTATPTGMTGFPGPGASQLSMGGASSAGPGEPRSPSSKRSSGFWGQEVGWDACHEISAESGEGVEEVFRVVTRKLVEQNRKMQQALLAATMTPGTPYEGGMGNDYFDGMNGRGSFRVGRDRRSWLFSPGFSPAVTMENQGQNQAEQNGQVEITKPRSKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WL27</accession>
    <name>A0ABR1WL27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transglycosylase SLT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668720.1">
        <property type="nucleotide sequence ID" value="XM_066809797.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042857"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045044026" description="Transglycosylase SLT domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="26403" checksum="CAC08FFAA201717B" modified="2025-10-08" version="1">MYASKLLLFVTAAVSASPLGSIVQERSDNDLAARAAPKFYSGPYTSFPGKNTWKSFDALWKANVPSMKAKGDTASDVDRIKSALQSVGKQHNIEPRVLLAIMMQESHGDVGAKTTISQPDGLSTGGLFQCWNCPGFNGKHGLTQQQITSMVEGGAKHFQENLAHRGGCMEPKCVYPALREYNSGANAVNLNNLSDAPNATPSYVSDVVQRLGAGSTKCLRPPRRGVSMASGSAFSWWKAARRIYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLM2</accession>
    <name>A0ABR1WLM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668847.1">
        <property type="nucleotide sequence ID" value="XM_066809924.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042984"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="250" mass="28358" checksum="0540F54CF12C2337" modified="2025-10-08" version="1">MVQQRESGQRRSMTYTSVPTSDAAYHSFHDDELFEPASPRHTVQTKPPSTWKNIPFNPKLARLQPPHLHNLVFHLVIAAADETFHPPGLPLRPQLPQGYSSANQLSRPGSQQQQQVPVAYYHFPSPEVCVVGQNHDGESDEDDDDDDDDDDNELAYPPPPQTTHYWTSDHTRRLEYAAIDAASQGVKGWMLRHVVPDCFIPKENRRLRFDDDTGSVRRYRLELDDVPEKEGAGRGRKLGWLFGRPSTAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMF9</accession>
    <name>A0ABR1WMF9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669216.1">
        <property type="nucleotide sequence ID" value="XM_066810293.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043353"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="51931" checksum="26553DA897C345FB" modified="2025-10-08" version="1">MGRSGYDISGMTSFGYAIDTPVSICTEATEDLEEEHPLYTVRTQFLHVVMAAHKRAAHDHDDINPDDGAGGGKGPMGPLEYENSNADEPLRKRIRSSDGGSSTLESAEKQSGTKATNKRRTPNRRLWLACPFAKKDPVRYRNCYRYYLGRIRDVKQHLTRCHRKPFYCPICWKTFEDEKLRDDHVRLGKCPRRPEVEIEGISEQQKKELGQRVSPKMPEEQQWFTVFNILFPLHPQPRSPYIDRDLSEQMSVFHDFYTSKGPELLLEFLESTGTVTWNLPQEERDLSTFQEGILGDGLLHIWDHWTSANTIEETCDAEPGTPAASQSHDSGVALQDMPGKPSSPEPQEQDSSHNGGFPAVAALKTEIPRVVPSTKAVLQVPTIINRHEEHSFLQQESHQTSHEPDSHNWSDILPFRMHAGTDSMLHDDILSQVLDSSIDGLGGTFELLPDFDFGIAWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMJ8</accession>
    <name>A0ABR1WMJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amine oxidase</fullName>
            <ecNumber evidence="7">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_005924</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="7">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="7">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669162.1">
        <property type="nucleotide sequence ID" value="XM_066810239.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043299"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015328">
        <property type="entry name" value="DUF1965"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF20">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09248">
        <property type="entry name" value="DUF1965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00766">
        <property type="entry name" value="CUDAOXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0186">Copper</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="DUF1965" evidence="9">
        <location>
            <begin position="252"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="8">
        <location>
            <begin position="336"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8084653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="789" mass="88073" checksum="EA88B6F209ECD3F7" modified="2025-10-08" version="1">MLPKFIYAALLGQHCTVSASRLAGSWLENRRLTSRQSAVNNQTTTPQCSSVAPGVTAPKENVWAPISSSDTAAVIEWLVQQPELKLTVPTVNGINGTWQNSVILVEAMMPNKTDVLPYLDGSAPAPERYAHVLLSNRASETPTYEDILVGPLPLDNATAKYFPLEFPFTRKTEGKVRNLDADGPVVQEKWLHPIGRSIEDIAMDLWGGTLSGYANDTMRIGSTDPVWQGEDGTVKRWYGVSRKPSGMFDTGSIMSAGLYMKSDVTGRDPSKWKLEGWYYNGVFYESTEAFRAAYFSPGFEKIGREPDAQWAWTERQGDPYPGDDTPAPMAVAAGPPRHKVDVARQYVEWMDFSFYLGFTRDTGLAFYDVKYKGERILYELGLQEALAHYAGSDPWSSHIAYLDSYYGFGSNTYELVKGYDCPQYATYLNASYYAHEQTHTHTDSICLFEFDADGPIQRHTTNGWVTVSKNVEFIVRAVATVGNYDYTFSYTFALDGSVAVDVRASGYISGAFEAKNDGFGYKIHNGLNGAMHDHVLNFKADLDVLGTANSVQLVKNKPISRTYPWSDGEVVNTMELERTFISNEDQGRFNWEPNGQGQVVVVNKDQKNQWGEYRGWRVLPSTPGSHLSIINSTVMRNTAHFAEYDVSISRAKDSEPRATHPYGNQDTRNPPIDFAKFFDGESLDQEDIVLWVNLGMHHVPHSGDLPNTVMTAARAGMKFVPSNYFDGDQSIRSRSQVRINYDKGKVSSLTKAGRDPICESTLMAYAGDSVINKYPYDPTNVFYEMDGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN46</accession>
    <name>A0ABR1WN46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Large subunit ribosomal protein L10e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006119</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669357.1">
        <property type="nucleotide sequence ID" value="XM_066810434.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043494"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018255">
        <property type="entry name" value="Ribosomal_uL16_CS_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001197">
        <property type="entry name" value="Ribosomal_uL16_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003239">
        <property type="entry name" value="PRK04199.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00279">
        <property type="entry name" value="uL16_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11726">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005590">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01257">
        <property type="entry name" value="RIBOSOMAL_L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8084848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="219" mass="25086" checksum="5C34EDD6C7F50D0C" modified="2025-10-08" version="1">MARRPARCYRYCKNKPYPKSRFNRGVPDPKIRIFDLGRKRANVDDFPLCIHLVSNEYEQLSSEALEAARICANKYLVKYAGKEGFHLRVRAHPYHVVRINKMLSCAGADRLQTGMRGAWGKPNGTVARVNIGQILFSCRTRDSNRAIALEALRRSQYKFPGRQKIIVSKNWGFTPLRREEYLEKKAAGRVKVDGAYVQFLSNKGSLAENMKRFPEAFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPI1</accession>
    <name>A0ABR1WPI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Taurine catabolism dioxygenase TauD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669948.1">
        <property type="nucleotide sequence ID" value="XM_066811025.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044085"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007817">
        <property type="entry name" value="Isocyanide_synthase_DIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37285">
        <property type="entry name" value="SPORE WALL MATURATION PROTEIN DIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37285:SF5">
        <property type="entry name" value="SPORE WALL MATURATION PROTEIN DIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05141">
        <property type="entry name" value="DIT1_PvcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="3">
        <location>
            <begin position="555"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="653" mass="73661" checksum="CC7E42D410D14DCF" modified="2025-10-08" version="1">MSTTTLTTVPATLEHHVLQHTPSLILERSHEKPAVPSNDTASRILAIIERYRLLRPGQSDISSESNVRFLEQIAASVSAGQPIRMCLPAFPFKSPNTVTKVLGQLPDKAEEFALAHLHGMCAAIQDIYSPGAKLTIISDGLVYNDLLGVSDRDVWAYGTALRKLSAEKGFSRYIGFARLKDLVRIQEDLPDELDEIVYVCNASNFRHAFLAQFGDERLDVSCRIKEDDDTCMTYRGYIRFLSTDLLNVYPTGPGRSKAQYKKGIQYIAKMMLKRGDAFARAVKENFSDQLRLSIHPSTFENKMSINLLPTDTSFTTPWHCTIAFRLDGTTTTGHRELFENDDAWELVHENGRPSFFRERSDLYSLVRGQEDDDQCLVSVSPIYPAGLLVRPADGSSRRLSIVDIDAQRLRSLSEHNSPVVLRGLAGTTDRDRFVAKAHELGVPRPWKFGLVLEVKDEGASTQGLNNVLSAEWMPWHYDGLFKTETRTNPDDGSETVVSIPPNHRSLPQGHRLHPLRLLRPNHQVPPPSLPPLESLRPLKWTVQTGGFGNLQLTDLPLFADHPTTGRPCLRFHEPWPQSRTRFQPTSITIQDREPETSERICAGLAELLHDRRVAYYHAWEKGDLLVSDNILAMHTRSDFTAGCSRELWRIHFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ48</accession>
    <name>A0ABR1WQ48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_005832</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669070.1">
        <property type="nucleotide sequence ID" value="XM_066810147.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043207"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="30"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8084561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="14847" checksum="57B554E06D8E471F" modified="2025-10-08" version="1">MAPKAADKKPASKAPATASKAPEKKDAGKKTAATGEKKKRTKTRKETYSSYIYKVLKQVHPDTGISNRAMSILNSFVNDIFERVATEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSSSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ57</accession>
    <name>A0ABR1WQ57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Polysaccharide lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668738.1">
        <property type="nucleotide sequence ID" value="XM_066809815.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042875"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025975">
        <property type="entry name" value="Polysacc_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14099">
        <property type="entry name" value="Polysacc_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046893790" description="Polysaccharide lyase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="27697" checksum="E80649B742972E7C" modified="2025-10-08" version="1">MVHFSQLAVSALLCAGYATAALLVDYNATRSDDVAKMGLANLEAARDKPQHGNTADLYIKADNDWKGAKSAHFHRKQGDIRAEYHALRGNTQEGKTYFIGYQFALGSTPDNMMVFQWKEYIANTQGKGQASIPLRLIVKNKTLQLNYDPMLSEGRQTLWSAPIKPKTVYTVALEILAKDAGQGHVRMWLDGKPVTFDTTKSTLLQGNMFPGRSEPKFGIYNGEAVVTDNWVYQVQIGEAKKDLDSKFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQA1</accession>
    <name>A0ABR1WQA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670230.1">
        <property type="nucleotide sequence ID" value="XM_066811307.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044367"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="2">
        <location>
            <begin position="245"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="760"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="880"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="979"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="779"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="837"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="908"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="922"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1114"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1161" mass="126676" checksum="E23B273946437311" modified="2025-10-08" version="1">MLGQYCGLMASLQNLFDKQSICNNSIGILSGIPRPAWVVPRAQHASNNQILNNATKENNVHTASGQAAETIVATPAARTPFPLPSRPPTAVGLSASQFQTDAAPAATVLDGSKVQTSTSTAVVPKISPPARSRSFSDVQADIRSLVPDIGAAQVSRAVTEPIPRTVTGPGSPMGGILGTTQAVTPQPGNIAPEDPATFTMKPQQQQPPPPQGKKQQELGSQRVRELVAAEAHCNFLNPRFVTRDIVYDTRVFANECCRVRGNPIFGRRLVLFSDGSHCTVTRTASAAVVFRRFYDMSTKTEPPWAKESYGVLRLTHNKFETIALMAALEIVQHEAKVFFASTLHNEEPLRVYLFTDSTSAMSDLEQVATCTVREDKQKKNPHMLHLMKIWRDLHSDVHNGRLKLEVHWVKGHIGAEGNEFADILAAKTIEVTKKLHFARPASSPLGQGYEVFPLWQMEQDLLSQSIIRSQAAAITHQPPPVAEGFQKAEETFIKEEEDRAKKAAQQDSLGQIRKIFADFFAETRKNAEKQNRHAIDELRKELDKQPKQIVYQQDVTKALKINRADLQEMLRKELSKPPKESPQLEQAIKSQTHNRLAFDELRIEIGKQNRRQDAQDAQIESLMMALEEASSEWRDTLAAQCREIKALRQEGQEMLRAMREETRDAIKVITQAVAARNSVKHTGCQTDEASPAMEEKPEKVGLAAEAETNDDETRSTTAASSEKPAVDPEQVTENVASCVSSEESHEIVRTSFEDAVSNFGQSGDLARQELAEEEEQTDDNSSTPTSSRTEQPETFPVEAASAVANPESADETATTCNNSEEESRETASTAFEVAPSCEDHSDVESEGHDVIEQVDQEDTGFFAPAEPAVLPEVIDLVVDADGPNDTAASCASSEGIPAAEVEELEDIDAAKPSESAERSAEEADAVDDPEQPENTITPCEGSEEVPVPAKEEWEDDTAFSNPARPAVVLKVLDAMVDSGRSDDTTISYESAGDTPAAEQEEEENSPAANPAETVMVSAGEATDVVDDSGMPEDTIASFLHSGEPSTTEQEAQEDTDADANPPEPLVVVVSTPEEEAELVDDSETPEDTITTCSSSEKASVVEHEERGSGATVLGETTSRSTASDFREEDGGKTPGKLRRRDKLLQKLHVRWPGKKKSKDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQG5</accession>
    <name>A0ABR1WQG5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670288.1">
        <property type="nucleotide sequence ID" value="XM_066811365.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044425"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="318" mass="36071" checksum="72239A858F8AE47C" modified="2025-10-08" version="1">MSGYKLSDLVELSEIIRQNRQNRAHSRFQPPPRPRHLNMFPSSHDPPGQTNIEPKEEEAWKIQSNTGQGPPSRSRNPVTSIPGQKRPHSPVADPIQSNKRREVDVSSTTTADQVSTSQSSGPSPASLTYKGNEYTLFQPWELNYLDALLFTQKQSIPRLLEAGHFILDNPRPGALYKIQRKEDFIAMPAYDPSQEKYRHVFIKVSYVQCEESCPGIAPITVLNITDGKEILNSYVWPRDKVIRWDKDRNDNTINEDVLVEASLKSNLLLGWEAARTKLAQFADAETIFVGHAMAFLMNALRISHKHIFDYGLARKIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRH3</accession>
    <name>A0ABR1WRH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669610.1">
        <property type="nucleotide sequence ID" value="XM_066810687.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043747"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8085101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="334" mass="35741" checksum="B14FA456ECA381D2" modified="2025-10-08" version="1">MAPSRTESVSVSGSSGCLSPKTPSSLSSRSQSSIARGPWADEPWPLFETPGRTHSAGHPAIHIANEAAHTYNAMFRGINSIFLQAPFVTAAEDVSDLLFLAHCLGCWIARHHNTLYSRVYPKYEAVFGRPGALTGPSPSQSEEDMSFISVLETLINYAAETQAQPQRYDPTVLLGILEDLAPGLHAHAFAQIIKSIGMVSLCGEPGSPAAEARAVALLNAWRALDAEAAAAADRPLVLPMLVRLRDTTFEGGNDWPRLPVLAVHVVADRLSPAHAGSWRFLPCTIWGKPQELPFLAPQGKEPKGKGKEVAWVSSLASTTHSSSQSLVSPTPVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRJ8</accession>
    <name>A0ABR1WRJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006447</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669685.1">
        <property type="nucleotide sequence ID" value="XM_066810762.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043822"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF2">
        <property type="entry name" value="SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="22"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="341"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="412" mass="45675" checksum="118AEF9025C1D6C3" modified="2025-10-08" version="1">MDAFSIEAFTLLGIGLTVVALRTYIRVHAIGPKGLQSDDYLMWLVAFAFSMETMIAYMVNHYWQGLANSSMTDEYRRMLSPSDPEYRLRVNGSKTHIVGWCSYTLVLWATKGSMCAFYLRLTDGLEPLAGRVRIGFYILAATYVAVTSNILFACGLPFEKNWQIYPDPGNSCQTTVSINNYIVTMVLNILTDIYLMAIPVPMLLHARLRTVKKLGLCLLFSGGIFVGTAAILRCVLALKASPPARPFPDLCLQDPKDNADISASWAVRESFVAILVTNMPVLWPSILKATQFVRSTLLLGYDANRTEDGGGGGSSQRPLYELRTKKGRRVRRSMHHITTSGFSEFTGGTTATTLSPGSQDIPGSGGGEEQKRPLCQREIRVHIAECMRVDEAAPARLRVSEREYYAQPLSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRT8</accession>
    <name>A0ABR1WRT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006762</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670000.1">
        <property type="nucleotide sequence ID" value="XM_066811077.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044137"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046734015" evidence="2">
        <location>
            <begin position="19"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="234" mass="23081" checksum="4968F893D4878939" modified="2025-10-08" version="1">MRVSTANVLLLLTVGSIGVVIPRNETAALNLMARQDKPPAEASAKSHESSAAAASPETKPPAAQSAKSHESSAASSAASAASETTPPPAGTSAASPETTKPPAEANCIPETTPAATSAASPETKPPAEQSAKSHESSAAAPATTPAPETTPVGTSAASPETASPETTPAPAPVTTETPAPVKSTYGAQQPSGTSEVSPVQTTTTEASPAPAPTQTYGSSNNARMLRVARNITVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRY0</accession>
    <name>A0ABR1WRY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HNH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670164.1">
        <property type="nucleotide sequence ID" value="XM_066811241.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044301"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37827:SF1">
        <property type="entry name" value="HNH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37827">
        <property type="entry name" value="TUDOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH" evidence="2">
        <location>
            <begin position="203"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="292" mass="32429" checksum="2A1F6186E1E7F6E1" modified="2025-10-08" version="1">MAGESEPEQDYQKNFDLFRDCLATVLIEKVSKPQPKARRRAKATSRGSTTSAPASAASATRPNNGTSVSDSNLEPSPSTAQDTTAEDLADFIDYIATEIYSSLPPDLQTLDYYIWKQDQKDDGPLQSRYTLPLTSSDVSSALLLPTLDPSVAESLHAYGLLREATQEDLATLLTPALTSLLESVTAVPPAPSASKKAAQEAGCELCGRDWVPLTYHHLIPRFVHAKAIKRGWHKPEDLQNVAWLCAACHRAVHRFASHEDLARYYYTVDRLLEQNEIVQFAKWVAKMRWKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WS32</accession>
    <name>A0ABR1WS32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_006684</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669922.1">
        <property type="nucleotide sequence ID" value="XM_066810999.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044059"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF2">
        <property type="entry name" value="SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="21"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="415"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="288"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8085413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="441" mass="48640" checksum="3C5889190F178180" modified="2025-10-08" version="1">MGAQENEAWILLSLGIWIIGLRTWVRWEMVGIRNFAFDDYLVCITGLVFIAETIAAYLVGALFDGLTNSYMTDEQRARLDPNSTEFYKRVWGSKIQVLGWSFYALILWSLKLCLATSYKRLFERTTIKKSRLLINIAYYLLGGTYLIVALSILLSCQPFHKFWQIYPDPGNVCQPTRSSVYVLVVVILNVLTDAYLISIPLPLLWQVNIGLHKRLPLMALFSGGLFIGIAGIIRANVILNSGPDGAAAGSRWAVRETFVAIVVTNMPFIHPKIRAILHAYKWTKNWVTGSSRSRSGRSTNRTGTGGAASISKSQNRKGAFQLQDLSTKKKPQKSGYGHGHFTSISSRTGKVSEKSLGTSSVAAWESDEHILRHGQDAASVSSSIRPGQSELVAANGNGIAVLHQVTVRESLAGNDDEDVGLSTPDWEYNTSVRKGKGPGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWY3</accession>
    <name>A0ABR1WWY3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional activator Mut3p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002563</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670496.1">
        <property type="nucleotide sequence ID" value="XM_066806878.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039938"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF1">
        <property type="entry name" value="ACTIVATOR OF STRESS GENES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="107"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="566"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="566"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8087602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="840" mass="93426" checksum="86EDB039AB7D1E97" modified="2025-10-08" version="1">MAQQNMSSVAGERLGAPAAAAATLPLRVPRKRRRTTKACDDCRRKKIKCDGKRPCSSCADFNSDCLYTRVSQREGDARSSPSKDELKQRLRVAETLLRRFLPDVDLDSLSGSSPVSQEGGSPVQYRAGPDAADANYSGPSSAAASTPAAASDASQDNSRGRFIPLVENAHQLDRTDTGEYNFHGMSSGAAFLNRITQYLPGLPRYDSRMPFLPQPPRPSSFVDHPTTELPAHLRSPWSQLVSHGISRLPLRQLAHDLCEYAFSRASCLLRVVHVPSFWEAFERLYEERPQRYTLAQQRFVGLLFSAMALGSMYDVDENDPTNPDHYAVAIERGYHYYASARHSLQDITECCDMTTLQALVFTIQFLQATGNLNGGHTFVGIALRAALRMGLHRHLPHASLPAVEDETRRRLFHTIRAMDIYLSTTLGLPLLLQDRDTDQRWPTEVDDEHITADGVRAPPPGTPSFIEAFNAHARLMQILAKVVEYVYPPTGTDKGPRDVTYMISVAKIKEIEQELHDWQGRLSPTWRAGPQEVPQITRVKILLRFAYAHVQMMLYRPFLQYYSQARSPPATTTPSTAERPQQQQQHAGGDERYLALATAGINVCRNILHIGLEIRKQEPVLIGPYWFITYTQFFAVLSLLLYVVHNPGRPGSLDLFADARLGRDCISSLTQRSLAADRVTAALNSIFDHLPPPFRSAEFFNNRDSPYETSGCGANSRTSFVTAYVPPPMTAAATSRQWPGIDASMSSSSSSSSLTSTRFHVDALQATRAHPSQLQQQPYQPAATTTNPMDLLLNDPFEYPVLPGVSLAEDGFGGLHDDLQLPLYEAQMDLEGQFLQFQGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXI2</accession>
    <name>A0ABR1WXI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycoside hydrolase family 92 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_002790</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670723.1">
        <property type="nucleotide sequence ID" value="XM_066807105.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040165"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF25">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046067387" description="Glycoside hydrolase family 92 protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="3">
        <location>
            <begin position="31"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="2">
        <location>
            <begin position="290"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="2">
        <location>
            <begin position="656"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8087829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="774" mass="84762" checksum="6F7DF8CE79B47702" modified="2025-10-08" version="1">MPIRWAPVLACLVVGALGDATVAEDFDPLQYVDVLIGSTNAGNVFPGASLPYGMAKAVADTNSSSNQGGFTLDGNPVQGFSVSNLGPSPYFSGSPSLGNFPFFVYPSCPGDDINLCDFPKKTRVNHGSFKPENVKAQPGYFSITLDMGVQAEMTTTQHTALYRFTFPNGPGSNGTYPFVMQDLSDLSDSRQDNGTVSVDAQTGRISGGAKFLPSFGSGSYTAYFCTDLSGPSIQDSGIYVNSRATTEAKDLTISRSINGYPLPGGGFVRFQDATTPILARTGVSLISTEQACANAEAEVPDFNFDSVTKAAKDAWKAKLSPITVSAGGGVAKDLITNFYSGIYRTMVNPQNYTGENPLWKSDEPYFDSFYCLWDSFRSQIPFLVILDPVAVAQMIRSLIDTYRYEGWLPDCKMSLCRGYTQGGSNADNVLVDAYLKGISDGIDWNVGYQAIVKDAEVEPYDWATHGRGGLDSWKSLGYIPVQDLDYKGFGTMTRSISRSLEYAYNDFCISLMSKAMNNTADQEKYLDSSENWKNVFYPDQTSFLPTGVDTGFKGFFQAKYLNQTWASQDPLTCSNLDTTGIACSLQNTGRETFEDSTWEYGLSPRSSPFSNITMLADQARARRGRTSTFLGTSTRLQEVSREMTIPARWAQCVPHHAPFFESVNLTHPTTGKTATIRNVNFDPSYEAIYIQSATMNGQPYTKNWLDHSFFLEGKELVLTLGKTESTTWGTAVKDLPPSTGKYVGFNGTASGQRLRSKSALKYRSDTWKMDAFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXN4</accession>
    <name>A0ABR1WXN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670806.1">
        <property type="nucleotide sequence ID" value="XM_066807188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040248"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="196" mass="21243" checksum="F556239F7F48EAC2" modified="2025-10-08" version="1">MDDYTWITLSRGTRACSTCGDPVCDTCAGNHSEDSDNNNSGDEDDNNSGDEEDNGRGSDSGDEGAKSEGAKSDDSDDNDDDDQDTAPWTRSTCDTRYDDEDDRDTAPEWRNSDDEDDGNGDTDSDNDIDGDGDGNSDGDSGGDSGGDSDGDSDGDIDDNRDGDRYARTDDEDDRDTEYWTDTRDTRYDAEDGEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WY31</accession>
    <name>A0ABR1WY31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">WD repeat protein mio zinc-ribbon like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003023</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat mio family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670956.1">
        <property type="nucleotide sequence ID" value="XM_066807338.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040398"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037593">
        <property type="entry name" value="MIOS/Sea4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049092">
        <property type="entry name" value="MIOS_a-sol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031488">
        <property type="entry name" value="Zn_ribbon_mio"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453:SF9">
        <property type="entry name" value="GATOR COMPLEX PROTEIN MIOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453">
        <property type="entry name" value="WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21719">
        <property type="entry name" value="MIOS_a-sol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17034">
        <property type="entry name" value="zinc_ribbon_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="MIOS-like alpha-solenoid" evidence="6">
        <location>
            <begin position="533"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="GATOR2 complex protein MIO zinc-ribbon like" evidence="5">
        <location>
            <begin position="946"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="426"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="465"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="435"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="999" mass="112713" checksum="70520FB359C17A32" modified="2025-10-08" version="1">MDRPEPGLIKWSPNSAYDSFLHVNLQHRIVQFYEATGLVAVGTSSGVVNLLRVDDDSNAYMELNLRVSRLCHAVAFNTGSLLAVGLERVRNDQCLHIWDVSRVSPTDANVPGFALDNSSILDPVNRLEPSVAVSSVKFFEDSPQTLAAGIKNQGIRIYDLRDPNGAVVTYPTKMNNNLSIDYKDPNYFASTALDQPSVVIWDRRATSRPSSSPSYLEAVDNDDLPWGAALKLDQAIDVQPEQFADKHSLIRSLRFCRDQRGLLGVLSRTGQLKVLDLHREFTTPDMEYEGSPELLQVRRSYELDLGYSSHDKRNDRIVSFDWVTVDSPALTPRAIVLRANGAFDILEKPSHTTDHLYDMVPWQPPYRGIEEPGSYHDLMQFDASQFPEMVGPLLVNEALSDVPIFGDTPADVDAIVNRTLSSQPSEYHKTHDIEASNTELPETYSNGSSTAEKLRVLRQFAKEITRESKPTSKSGKRHSTVEDITQEMDDLSTDRPGPPSNRQLHERLLSLTQETAGFPKDAQVLLDHVTLLRASDKYLFNFAANRDIVSDDPWIRDVWDWITGAEQDAEDEGMVAMGIDISYMGTRTIWANDLGQRSSTRLAEGMAIPDRAAWERCLQSIIKQFGVPKYEGIETKWPAHRQVCLRICSWGRSNQTDFTDFAKTPVSERTSSWHTMATAHALFRGDTKEAIQILKRASTEYPELLFVSLALQLIGRGDVNLAKEQLDFDDAVASKTDPYLRAISSFIATGNWETIANQDSLPLRERTFVAFRYFDDEILSKWLDKQVARAVHTGDVEGIVLTGITEKLVDILAKYVEKFNDVQTATLITSICAPRYIDDYRCHAWRNAYRAYLQRHKAFYHRTKFEVESTKKSKRDGVPTVKPPSRQIALRCVYCDAEYELSKTGASQPPVTGLRNPLMTTSMKSVCLEVVGVSRSDKPEAATDPEKKVAARFPTFCLKCEHVLHLDHARQWFARHVECPVPECRCRCNLRANPELNYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYM0</accession>
    <name>A0ABR1WYM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peroxisomal membrane protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_003215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671148.1">
        <property type="nucleotide sequence ID" value="XM_066807530.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040590"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019531">
        <property type="entry name" value="Pmp4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15460">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15460:SF3">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF013674">
        <property type="entry name" value="PXMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8088254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="225" mass="25264" checksum="0E51C1837827F0BC" modified="2025-10-08" version="1">MSSALTNVKDTIERFLLDPANRDLLAIVKGARNGAVYGAKVRFPHALVMVFLFRSGTFRQKADLVVKATRTHARNLAKFATIYKTICYLLKNYGATPGKEGKYDTLLAGLVGGYFVFGGRSPKTGKISSVNQQIVIYVFARVVLALARLAVKPGHGLPVVSKERTSAQISHYAWPVFAATSWALVMHLFRYHPEDLQPSMRGSMNYIYKESDHWNSLRNFIWHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYP4</accession>
    <name>A0ABR1WYP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671176.1">
        <property type="nucleotide sequence ID" value="XM_066807558.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040618"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="2">
        <location>
            <begin position="16"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="121" mass="13282" checksum="5FB288E6F848A5B8" modified="2025-10-08" version="1">MPSNVGLTPETAAAVPSDQYATYERGGQVVFVSWISYVAYVWGIKAAALSFFARLCAGLPREMSAVRYVALFTGMSYLASILTQVLGCLPVHHSWQVFPFPGEQCTTRILNFYIIGVLDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYY7</accession>
    <name>A0ABR1WYY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-dependent helicase fft2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003312</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671245.1">
        <property type="nucleotide sequence ID" value="XM_066807627.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040687"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="617"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="980"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="61"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="157"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="278"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="385"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1163" mass="129313" checksum="5D3740023EE1E9FF" modified="2025-10-08" version="1">MGRLSSFAGSSSPRLPGTPSMGAQAKGKMSKFDIEDEDLDELAENIPCSSPYFTQPTQIISRPSAANGTQPTQIVERKPTLHRSSPAPPSPGTVVEVPASSPFQTVRPAVKAAAYRASPPVNSGVKPAVKPAVKAAARIGSLMAPAGTAFRSPALLPRRTIATGKPKPRPADLSDDDLSNDYYKGMDSSEDDKPMRGNIQPALAVARSGRSTPVDKRKAPEDDIQPTDITDLRLRYLTKETHKIIVTTKPNITWRACKNAVVRNNLSAEAAINDLLGKPKQSSSSTIGRPAAAVKTKNLKQSKLFPSKTTVTSQPRAVSISSSSASESSESESESEPEPEQKKAPSTKTHSRSSKQTRIATSSSCIFPTLFTLIANFHTFKLSRNQPSESAPKKRGRLVRGSRKPSPITLADSDSDEDLPNLENLVSRKRKADPKSAPEVIDLTDSDQEEAAADTDSAANDSQPPSPTKGLTESSKVIQYFNECSAEDLARISGMKVSDTKLVVAARPFASLREVEQVSRKEKATSRKASRIQIGAAIVEKLVVWFKAFKAAADVIEDCDERGREIQSAMSRWELDRNGHETGKANSRPLPIHKKPALMDSSVQLKSYQLLGLNWMNLIHTKGYSGILADDMGLGKTCQVISFISHLVESEKSINNDRKPWPNLIVVPPSTYENWMNEFQKFAPGIKLYPYSGQARRDTDPDEVQDYHVVLTSYSQVDRKREDVEWLQGLDPYAAIFDEGHKLKNTSTFVYKQMSQVPSEWRLILSGTPVQNNLKELLSLLKFVEPSLFGKELVGHLDTIFQAKVANKDVENFALLAKERVGNARVMMAPFILQRRKADVLDLPLRKDTRIVVPLEPQQKEIYESIRDRYLHKDKAAKSKVSNPWMQLRKAALHPQLFRRHFTDDKVKKLVDILWKRCSEEELDVQSKEPRHKEQFQEFLMERSDFELHTWCKDFPKYIGHLDIPNRSWEQAPKVAKLLELIQGYMKTGDRCLVFSRFEMVIDILRETFHATDIPYCELTGRASVQARFPEVERFTNDTTIPVFLLTTGAGGTGINLTAANKIVIFDQSDNPQDDVQASNRAHRIGQTREVEVITLITENTVEGLIYNSCVKKLMLAACVEGAAVDDSESVEEQCRKLMLMDSNAEAHALEVMEEVVEEAGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZ72</accession>
    <name>A0ABR1WZ72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparaginase</fullName>
            <ecNumber evidence="2">3.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003425</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-asparagine + H2O = L-aspartate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21016"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="EC" id="3.5.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the asparaginase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671358.1">
        <property type="nucleotide sequence ID" value="XM_066807740.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040800"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08964">
        <property type="entry name" value="L-asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="entry name" value="L-asparaginase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004550">
        <property type="entry name" value="AsnASE_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020827">
        <property type="entry name" value="Asparaginase/glutaminase_AS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00520">
        <property type="entry name" value="asnASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707:SF28">
        <property type="entry name" value="60 KDA LYSOPHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500176">
        <property type="entry name" value="L_ASNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00144">
        <property type="entry name" value="ASN_GLN_ASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045363319" description="asparaginase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="L-asparaginase N-terminal" evidence="9">
        <location>
            <begin position="42"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase/glutaminase C-terminal" evidence="10">
        <location>
            <begin position="256"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="367" mass="38445" checksum="65CF7483663A6875" modified="2025-10-08" version="1">MVSIKLLLGLGASLALASPIPAPPSPVLLGRETGHFNASRPNITIFATGGTIAGSAGSSDQTTGYEAGALGVEVLIDAVPQLWNVSNPSGVQFANVGSSEMTPALLLNLTQQVQAELDKPEVQGVVVTHGTDTLEETAFFLDVTLRFDKPVVVVGSMRPATAISADGPINLLEAVTVAASPAAARRGVMVVLNDRIASAYYTTKTQANAPDTFKSAEQGFLGYMLDIKPIFYFEPALPVGRPYFNVTATEADALPQVDVLYGYQGLDPKLAAAAVADGAKGLICTGMGAGSWTKPGQKALKQLVEEHGTAIVFSRRTTDGYVDTQSVGYGGGFLNPQKARYTLMLALNAGYDEEKMHALFESQSSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZB6</accession>
    <name>A0ABR1WZB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GNAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671403.1">
        <property type="nucleotide sequence ID" value="XM_066807785.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040845"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="49"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="280" mass="30491" checksum="20559AD223C8832A" modified="2025-10-08" version="1">MTAEADKNTNTTAAHNGGDDKDGTVLVRTTFPSVPLPANDTRPHIHTARLLVRPLQQSDLAGLHALRSQPEAMTGTRLGRPDRDLAETQVELDFFRNGVAGSGEPPYLWGAFLPRSSTTTTDGKEGEEEEELLIGEGGVHSLVSDAAEASGWPEIGYKFRKEYWGRGYATEFLDAVLGAWWGLPRGTVEMRVNRRAVAVATNGDVDIPGGGEEDAVVEVAEHVYANAEPSNVGSCRVLEKLGFQRYHEWTEPDTQEHRVGEPLDLAGYLLEKPGSRCLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0E8</accession>
    <name>A0ABR1X0E8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_003864</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671797.1">
        <property type="nucleotide sequence ID" value="XM_066808179.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041239"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF4">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="38"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="483"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="503"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="521" mass="56839" checksum="A3B6C77DAD6295DE" modified="2025-10-08" version="1">MSYSWVGAPTEFNGTNEETGGDSTTENLNQWYQSGDQAFIIVAACMVLIMVPGIAFLYSGLSRRKSALSLIWVVMMSFSVIIFQWYFWGYSLAFSSTATNGFIGDLHHFGLINTLAKPSPGSPLIPELLYSFYQMQFCAVTGALVIGATAERGRVLPAMVFTFFWATIVYCPVACWVWNVNGWAFKYGVLDYAGGGPVEIVSGMSALAYSWVLGRRHEKMMLNFRPHNVSLITLGTILLWFGWLGFNGGSAFGANLRAVMACWNSCLTAMFAAMTWCLLDFRLAKKWSMVGWCSGVISGLVAATPASGFIPRGPRSSWALSPECAVTSALRIDDSLDVFAEHGIGGMVGLVFNALFGAGYIIGLDGVNTGAITGGWLDHNWKQLYIQIAYIVACTAYSFVVSAIIAKIIDIIPGLHLRASEEAELLGMDDDQLGEFAYDYVEVRRDFLAWTPAKEDPHSGHAQIVPQHGIEEHAHMANTNGTSLESEAEKIGISARAPAKQAAIDKEVHEQDPRDPATTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0Z7</accession>
    <name>A0ABR1X0Z7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleoporin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004052</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671985.1">
        <property type="nucleotide sequence ID" value="XM_066808367.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041427"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039462">
        <property type="entry name" value="Nup159/Nup146_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16755">
        <property type="entry name" value="Beta-prop_NUP159_NUP214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup159/Nup146 N-terminal" evidence="5">
        <location>
            <begin position="60"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup159/Nup146 N-terminal" evidence="5">
        <location>
            <begin position="280"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="454"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="490"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="615"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1359"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="500"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="615"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="677"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="785"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="822"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="858"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="899"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="938"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="985"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1022"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1034"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1084"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1372"/>
            <end position="1385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1473" mass="154655" checksum="37026B12D5B7A795" modified="2025-10-08" version="1">MAFGFGNVGNALGPGPAQGTGAGSVNQGPDLEVVSTETLGFLSIAGDAKVRFTSAWSPAPAQNASLLTIASRKGLVAAAGPDGLTIATTENVRKAFSGPKDGDSEFRSFNPELKLPVPTRICQLTFTADENYLILSAENGGGLAVYNVETLLQGSTNPAFEIPTNGGVAKSPDTESNAREGGAVRCCHGQGQPPHSRYEEQGLCRWEDRPDIEGPSQLRRLEYQGQTAGRWIRRWHNTTDDAHWRLEGHDSQAPIPEWELLCLIPGLAGERPILVYPCPNFNYQKMTDPVDPFGSPKVPHHTAARLKDFDPNLQDLLVFSSTATPDIGLMSRSKTPLTSEMDAAKITGVFTTTELADDSKRATLPMGESLDSGLPVGTALDLSSKEPVYKPIPTDEMEQSAGPLPGYWVLNDEGVLSAWWIIYNESIRAGATYRNLVAAEASAPAIAQPAQQNAFGAPSTASGTQAQPSPFGAASASPFGAPSSLGKPAFGGPSALGAKSSPWSSQPASSSTGGAAFGSSSFGGQPAASAPKFGTPSFGQQSGIGAKASPWATASTATSTPAFGQSGFASAGIGSATSASPFGSAAGTSKPSGGFASFANQGGFAALSNGGAKSGTSIFASSKPADSSMETNSSTSFPPPSSKPAGASNVFGSHPFKLTSSFQPDPNQKADEGSKEASSGGTSMFGSGFASAIGEAAAPTSPGPFGSKEQSTTPTTTPAPSKFFSQTAPAPSGGGLFGQPSKPTSSIFGAPKVKDEPESPKPLSGVPSAPPPDSTSKTSYPLGESSSSSTASAGSPDSRKSPEEAPLPPSFPTSKSKPAERLPLPSDSPPSRGDVIPLPPDPSTNKKVYNVKFPPLPGEKEEAKAKPKPEASDDAPLPPDPTTNKKVYDVKFQPVPGVASQPAKPSQPPAKARSVFDREPPKSTGMFMFPTNPPPVSDSEEDDESDEGEAEDASEAGTEGSGVDVAKDLSPPPESKDSKDKSPGFTPQSSFDGLGGSFSTISRPEPERKSLFGNTGQGIPTFPQPNPISPRSPSPIRGVIPSRVMGSEQTRSFSAPGMASQLLGVPQRTQSRPISGRESVAVDSHIEQQRKAREKKEAEEAQLLVDEEDERKQELLNASIKPTLTLDEFIAHAGPAPAADNNIPAQVEAVYRDINAMIDTLGLNGRSLANFIAGHSEAHRHERREKEDLSNSDDWTIGELEDLSRIISRDLAHDLREARITDAEDKVAECQDLLRDLIRDRSKRNDLQKIIHARFDPDQATANRALPLTTEQAGRQGDLRRDLAHFTRLLAETEESLTMLRAKIAAAGGANGKGGPVPTIDAVVRTITKMTAMAEKRSGDVDLLENRMRSLRFASPGTLNFGSSTRSREGSPFSTPKKQLTSSFMFSPDPSFRESTPGHHPRASAMRHSLSASVASIGGGMFAVPPRKKMSGFGEVEKKAVKERRARRAVVLGKVRSAVEQRGPVVIALDETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X119</accession>
    <name>A0ABR1X119_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dolichyl-diphosphooligosaccharide--protein glycotransferase</fullName>
            <ecNumber evidence="6">2.4.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PG997_004057</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N(4)-(oligosaccharide-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22980"/>
            <dbReference type="Rhea" id="RHEA-COMP:12804"/>
            <dbReference type="Rhea" id="RHEA-COMP:12805"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="Rhea" id="RHEA-COMP:19509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:50347"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57570"/>
            <dbReference type="ChEBI" id="CHEBI:132529"/>
            <dbReference type="EC" id="2.4.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endomembrane system</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.18" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671990.1">
        <property type="nucleotide sequence ID" value="XM_066808372.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041432"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003674">
        <property type="entry name" value="Oligo_trans_STT3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048999">
        <property type="entry name" value="STT3-PglB_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048307">
        <property type="entry name" value="STT3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872:SF1">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02516">
        <property type="entry name" value="STT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21436">
        <property type="entry name" value="STT3-PglB_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="281"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Oligosaccharyl transferase STT3 N-terminal" evidence="18">
        <location>
            <begin position="123"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="STT3/PglB/AglB core" evidence="19">
        <location>
            <begin position="504"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="687"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="692"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF21436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK8089096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="710" mass="79677" checksum="00C18343DA90D762" modified="2025-10-08" version="1">MAVATASDPSPIQVLADFGKSKSLRTLLRVLILCFIAGAAVSSRLFSVIRFESIIHEFDPWFNFRATKYLVANGFYDFWDWFDDRTWHPLGRVTGGTLYPGLMVTSGAIYHALRAMTIPVDIRNISGLLAAAFMGITPGYISRSVAGSYDNEAIAIFLLVFTFYLWIKALKLGSVLWGALCALFYGYMVASWGGYAFITCLVPLHAFVLICMGRYSTRLYVSYTTWYALGTLASMQIPFVGFLPVRTSEHMPALGIFGFLQLVAFIYYIRSALSGAQFKAFLFVGLGAVFGLALLALVAMTSAGYIAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTAWPAFFFDLNMLIWLFPAGVYLCFQDLKDEHVFVVVYALFGSYFAGVMVRLMLTLTPIVPPKAKDPEQEDVADISSKKTKQSAGSLRSANSPYVGVYSFLSKGLVSGIMTIYLLLFVLHCTWVTSNAYSSPSVVLASRMPDGSQHIIDDYREAYQWLRQNTKEDAKIMSWWDYGYQIGGMADRPTLVDNNTWNNTHIATVGKAMSSSEEVSYPIMRQHEVDYVLVVFGGLLGYSGDDINKFLWMVRIAEGIWPDEVSERKFFTPRGEYRVDGEATETMKNSLMYKMSYYNYHTLFPPGQAQDRVRGVRLPDTGPVLNTLDEAFTSENWIIRIYKVKDLDNVGRDHAAAASFERGHKKKKATKKRGPRALRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X193</accession>
    <name>A0ABR1X193_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004173</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672106.1">
        <property type="nucleotide sequence ID" value="XM_066808488.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041548"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051855">
        <property type="entry name" value="eIF2B_beta_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="116"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="438" mass="47672" checksum="01A23AC5C939B33B" modified="2025-10-08" version="1" fragment="single">KPPYTPKDGSPKGGYAPTLDKFLDTLKSRPLEASIESLVSLLKRRQIQGSEPCALATAHILLQVVVMDKYTDVNQLLARIQGVARRLVAAQPRELVIGNIVRRVLGLIRDEALENRNEAGSDESISSPVRDASPPPMSASVSSLNESAPLTKMGRPGLLNALTRTQSMFNLLADPDTIPPVWSTGASPAPGSGVSTPMADPQSTDVKALRSEVIDGIEEIMDEIRQVDEQVQAYSDIIIHPGDYILVHQPCKTVQRFLTRSKRRCTVFLVVDPSAEDPYASFRKSMAATGSVVVNIMNIGLMAYMSRVNKVILSARAIMSTGGVLVDGGASVIARAARELGRTVIVIGGVYKLSPDNQIDQDTATEWGNPSKYVNYSDGRLVRQVTVKTAVSEYVPAELVNTYITNLGAHSRDHLHAIVNDHYKEADIEFDLYGTIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1U9</accession>
    <name>A0ABR1X1U9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal specific transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_004327</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672260.1">
        <property type="nucleotide sequence ID" value="XM_066808642.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041702"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF9">
        <property type="entry name" value="TAH-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="5">
        <location>
            <begin position="347"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="33"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="813" mass="89145" checksum="1F78C92CC02E125A" modified="2025-10-08" version="1">MTRGATGPALSPVCNGQKPCNTCTKRQLPCVYTPSNLDPGDSPVGSPTKRRHVDASPRSVRASLGDMKAQASHAVPAGMPNATPWDAVEMTPAAHPISGPRAPAPASTPVSVQKTPTQPSRRMTNPGEIDSDSRSRVSNASGAADEAEVYPSRRMLQDSTGRLLYVGDSASLSYLQWIRMIVEGISGPSDFTTDPRRHMIMEATMSLPPPSTPSGVLPDRHTADVLVGSYFVNTTGLVEVFDRDLFRTQMNECYEDPLSVEPSVLCSLYLVFAIGLVLARPRPGSPEEATIEKLRSDKKVNRAEFFFRNAKSLADPVSGFEDADFWSIQALLLMSLYMLSVSKRNASYAYYGMAVRSAFALGLHREDCDVIFTPVQRRTRRNLWRTLFVLDRFSAASLGRPTAISEEDCSEKSLDFPYKIDGTSAMLSEAEKISVAALDAAVKTCHVIGVTLKKVYSKRKISTVVAQDIAEQLEGWNESLHQALHWRQAIDHRLDPSHGIAILHVNLLQCHSIMLLTRPFFLYILKKAQEQETAGTSKPSRLSQRMEKFAQTCVEASQHTLLLVQTAWEAKYLPQCNPFVIHFVFAAGLIIFSNEFASLYHNPKAEEAIQSCKSFLKYCARYDAQAERVSWIVEAFDRANKSRQPTARRLSLPSRKIPIINIPGPNNTYDPMVGFFNPNRPGSQQSLPSLPPIIKQEQSMPNPGLPKSLPPILPSVLQQPSPEGSGASPVNTGLVQTGVHGMEGLGPHETEFDFDSLWPSNWNAHASAGPMNMPASQVDPSEAFGTFGLGQAPPGSLLSGSVNIPLYPPSDFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2B7</accession>
    <name>A0ABR1X2B7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004453</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672386.1">
        <property type="nucleotide sequence ID" value="XM_066808768.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041828"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01452">
        <property type="entry name" value="VWA_26S_proteasome_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="5"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="236"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="299" mass="31811" checksum="97ED5CDB79DB29F7" modified="2025-10-08" version="1">MPLEAVMIVVDNSESSRNGDYQPNRFDAQADAINIIFENITQSNPESSVGLMSMGGKGPEVLSTLTTERGKLLEGLHRTRKKISGTSHLATGIQIASLALKHRQNKSQRQRIIAFVCSPVADEEKALVSLAKKMKKSNLDIDFVLFGDLDNDAVQKKLEAFNNVLKSPDSSHLVVVPPSGRLLSDQLISSPILLGEGASGAGGAGGAESGGGGDFGGFDFDPTDDPELALALRMSMEEENARQARQTQADGDGAKPNLEGIKEEDERQPLLNEDGEASGSGSTGKKDTKKDGDDKMDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2K4</accession>
    <name>A0ABR1X2K4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hemolysin III family channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ADIPOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672543.1">
        <property type="nucleotide sequence ID" value="XM_066808925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041985"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF52">
        <property type="entry name" value="ADIPONECTIN RECEPTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="349" mass="38594" checksum="A8EF9D1D836969C2" modified="2025-10-08" version="1">MSATKKATGREPQFPAASSQNQNHHQHATMGGGSEKTLRQRGRAASASLASTAKNVEVQVEQALRRLVHWDDLPAWRRDNQFLLRGYRPDSGSYLGSLSSLFYVHNESVNIWTHLLGCGAFATGGGLALYHGFDALVAPRYASASRSDVLVFGCFFAGAVACLGMSATFHTVMNHSPDVAKWGNKLDYSGIVFLIVGSYVPALYYGLFCLPELLMVYMYGIFALGAGCGIVSWVEFFRTPAWRPYRTMMFVGLGVSGVLPICHALTTYGYKGLDQRMGLSWVLLEGFLYIFGAFLYAVRWPERSFPEKFDIWGSSHQLFHILILFAALSHLIGMAKAFDYHHTILGAQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X3Y2</accession>
    <name>A0ABR1X3Y2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">mRNA-capping enzyme subunit alpha</fullName>
            <ecNumber evidence="3 16">2.7.7.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 16">GTP--RNA guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13 16">mRNA guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PG997_005086</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:67012"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.7.7.50"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:67013"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the eukaryotic GTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.50" evidence="3 16"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673019.1">
        <property type="nucleotide sequence ID" value="XM_066809401.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042461"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07895">
        <property type="entry name" value="Adenylation_mRNA_capping"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001339">
        <property type="entry name" value="mRNA_cap_enzyme_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017075">
        <property type="entry name" value="mRNA_cap_enzyme_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013846">
        <property type="entry name" value="mRNA_cap_enzyme_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF17">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03919">
        <property type="entry name" value="mRNA_cap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01331">
        <property type="entry name" value="mRNA_cap_enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036959">
        <property type="entry name" value="mRNA_cap_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 16" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="5 16" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="mRNA capping enzyme adenylation" evidence="18">
        <location>
            <begin position="46"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA capping enzyme C-terminal" evidence="19">
        <location>
            <begin position="245"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR036959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF03919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK8090125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="391" mass="45484" checksum="29FDD046B136EC6C" modified="2025-10-08" version="1">MASDNSGPLQSIDAPGIKLPNEEAAGLRQDVQRLLGRERWDFPGAQPVSFARHHLKELRSKDYYVCEKSDGIRYLLYLTVDPSGAEAHFMIDRRNDYWYVSTGSTHIPTTKAEEGFHVNTLLDGELVMDDVGDGRKEPTYLVFDCLALDGQNLMSRELPKRLGYFKEWIYNPYKALYKKYPTERPFQAYVLGMKEMQVAYGIEMMFREVIKNLRHGNDGLIFTCLGSEYKPGTDPHILKWKAADENTVDFRWKLDWPLLQPDEEDLAEGWTEPYKLYHDVPQIQILAYHGGNGPDSYRPFGEMYMTEEEWEELKALNEPMDERIVEAYMDEQKRWRFYRFRDDKPNGNHISVIKSVLESIEDGVTKEELLGAAKGIRDAWKERQQAQSRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X422</accession>
    <name>A0ABR1X422_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GMP synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="4">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_005120</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673053.1">
        <property type="nucleotide sequence ID" value="XM_066809435.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042495"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000848">
        <property type="entry name" value="PRK00074.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="7 15" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 15" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="16">
        <location>
            <begin position="197"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="226"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8090159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="512" mass="56668" checksum="18220A6C0770A76E" modified="2025-10-08" version="1">MAPTKIEAESPHNNFDTILVLDFGSQTSHLILRRLRSVGVFTELLPCTTKVSELSWKPKGIIFSGGPSSVYDEGSPHVDPAVFDLNVPILGICYGCQEIAWRSDSKNVARGEKREYGQADVNVTKVGSHVDRLFAGLGDKVSVFMSHFDKLINLPTDFVVIANTKNSEFAGIAHKEKPIFGVQFHPELEHTPCGVDILRNFSTDICGAQANWKMGDFVQLEIARIRELVDSTVGAALMREAIGHRFKAIVIDNGCMRLNECDEVKKTLGEHLGIDLTVVEAGELFLSRLAGVSDPGEEAIEKEAENTPNSGKVEWFLQGTLYPDVIESLSFRGPSATIKTHHNVGGLPERMMNGQGLRLIEPLRLLFKDEVRAIGRQLGIHESLVGRHPFPGPGIAIRILGDVTQERVEIARKADHIFISMIKEAGLYDQISQAFAGLDTNRSVGVFGDQRVWGYIVILRAVRTKDFMSAEIFKFDLDFLENVSRRICNEVEGVSRVTYDLTSKPPGTIELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X925</accession>
    <name>A0ABR1X925_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_002285</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673896.1">
        <property type="nucleotide sequence ID" value="XM_066806600.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039660"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="10">
        <location>
            <begin position="4"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="11">
        <location>
            <begin position="953"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="2416"/>
            <end position="2493"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="953"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1103"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="985"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8091924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2496" mass="271540" checksum="A512225D72C3A0CB" modified="2025-10-08" version="1">MANQEPIAICGMSYRAPGIGRKGLWDYLAQARSAWTRVPADRFEESAYFRKGGDRSGVMSTQGAHFIDEPYGFDAAFFNMRAEEAKHSDPQHRLMLEVALEAAEDAGLGLQDIAGKKIGVFVGSGQHEYAQRLGDDEHVVQTFSGTGNAVCMAANRVSYFFDIDGPSVVSDAACASSVYAAHVAVNALRNGECNAAFVGTASLNLSPAGWLVLEKTGALSEHGRSYSYDSKASGFGRGEGAACLFIKRMEDAIRDGDPIQAVIRGTACNHSGRSDGITMPNGLAQQKLLWAVHNAAGLDPSDTPVIEGHGTGTGVGDPIESGAFTAVLGRNRTSANPLHLGSIKSNFGHLEGASGALAMVKAIMQVKNGIVLPTAGFENINPKIQDPEKVRIAEMPLPWPENEPRRCLITNFGFGGSNSAIIIEKAPEQPAKQNGITNGHSNGVNGHNGVATNGTNGHTNGTNGTNGHSNGSAVQSRRLFTFSAKTQKSLDAYLTSWDDYLDEAPESSDFFRDLSYTLGQRRTHFPYRVAAPADSVEGLQEALSTLKPVRVKDRIYNFVFTGQGAQYARMALELKSFKVFADALEEAESHLQKLGSPWSLLEELNKPAEDSRVNEAELSQPACTCIQLALVTLLTSWGIVPTAVTGHSSGEIAAAFAAGLVSFQEAVAVAYFRGQAAVRLSSQQSPDQKGGMLALGVGAEEATKLIDEHGGGYATVAAVNSFNSVTISGDKPVIEKVFKAAEAQGTFARKLNVEMAYHSRHMEQVAGYYLDAITPYCGQVSHGKDDAQRPIFVSSVTGQVEDSVGASYWIKNLVRPVLFANAVQGMLTLFEDSDNKLLKAMPKVIVEVGPHAALKNPIKQTVEIIQAEKNWGPASFTYVPTLVRGTDAEQAALDLAATLYTLGAPIQLGGVNQTGQKNARVLTELPSYAWDKTRYELRPRATHEKFCPGEDYHPLIGRKMPSSGGQERAYRQVFTLDEMPWIRDHVVGGSTIFPMTGYMSCAIEAARRTVSTQAEAFLVTDFHVSRSLEVLEEQTVDLVTKLRPAALGEGAFSTKAWSFEITTWAEKDGWTVHCWGQIEPEMAEMTMDTPTLKKGIPLVNNLAALDEKNIEDEYAKAAVRATQYGPSFKNNIKFYEGDGFTVLEHRLRDLGEARTDPFARGSPVSVDPPTIDGFLQGGGPLQYDEQGRRPAQMPNYISRFRVSNKIPSEPNSRFDVVMQKLSYDVKGGPPFESSRFRNIGSAEEIADPAANVPDNWAWEVLPKFDYLPADQLRKKVAESVPELGIEEDIRLEKLGRAGWYYIGEALKQTAGEDYSKLPHHYNRFIHWAARAFIESGLEFPEEPTELLNEVRSADAQGLLCCAIGENLVDILHGEVEPLEIMLTDNRLTKNYENGTNNYLSAVLGYYAEMLADLEPNQRILEIGAGTAGSTLPILEGLSKDRDEPGFMSYTFTDVSTGFFEGARTKLEKWTQRITYKKLDITEDPVAQGFALEEFDVVVAANVLHATPDMISTIANVRSLLKPGGKLLLLEGNVHNSMLLPFTLMPGWWLSEDKYREHGDGPMMTTSVWNQLLLDSGFSGVDTTIPSSWHADVPLMSVISSTRIGKQDESRELIVSGPFVDDVEQLGCTVDVRPVAEIDADDAPYYIFIDSLKESIMQNMTHEKFEHLQNLILHNTGLLYITPEGANPDANIILGMLRTVRMESDPKNLTLLQDVPSTPAGALAILKAAERLRDPEVTRHQDQDLVWKDGSIHFPRMLQLKDVKEQFAVEQNIAFLKNQNLWGKPGDRALEMTIDVAGSPDTLYFRRTEVGEKPLGDDEVIVRVEAAGLSHRDLEVVLGAVPWAPPGFDGCGKVIKTGSRVSHVREGDDVFFLSLESSALATYKQLPSWQIARIPAAISITNAATMPLAYSVAVLALIHTARTRKGETVLVHAATGAVGQACITLAQHLGATVFATAGTESKRDFLHTSYGIPKDRIFSSRTPAFRDSVMAATGGRGIDVLVNSLSGELLTETWALAAPYARFVEVGNKDTFLNNSLPMRPFNSGVTFAGIDLRDLHKHRPDDVRDVFAEVVRLVRSGVARPIGPLSSALKKLKSSDHSGKIVVTLGPDESFVAETPLRPSTVTMNHHATYVVTGGTRGIGLELAYWLIEHGARYIVVLGRSGAKGEDVQKLLAKYADTDVTIRALACNVGKREELAQVMESISDLPPVKGVVHSALLLSDKLFVNATYEDWEINTTPRVHGAWNLHELMPAGLDFFIALSSFSGDTGNIGQAIYAGTAGFYDAFAKYRNKQGQYTVSIALPVVLDVGYVVEHNITELLKMALGASLTMADIRALFKCAVSGSLEKPTPYVQASGRATAFKVYVDGQAVSNGSWKYFHPVHTKERLAEAAALKSRAAESNAATGGGGEATSWTAADDPEQGLTEALITKVAAMTMMEREEVLADAPLDSYNLDSLVSVELRNWIRRETTVELTLSAIMHADSLRALAAGILAQRNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9G9</accession>
    <name>A0ABR1X9G9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002459</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8092098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674070.1">
        <property type="nucleotide sequence ID" value="XM_066806774.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039834"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000530">
        <property type="entry name" value="Ribosomal_eS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047860">
        <property type="entry name" value="Ribosomal_eS12_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11843">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00972">
        <property type="entry name" value="RIBSOMALS12E"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01189">
        <property type="entry name" value="RIBOSOMAL_S12E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="6">
        <location>
            <begin position="31"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8092098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="147" mass="16238" checksum="E1B727B2F0928795" modified="2025-10-08" version="1">MSDVEENNAPEAPEEVEVSADASKGQMSVLDALKGVLKLALMHDGLARGLREASKALDRRQAHMCVLNEACEEEAYKKLVIALCSEHKIPLIKVPDGKQLGEWAGLCVLDREGNARKVVNCSCVVVKDWGEESQERSILLNYFQTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9P3</accession>
    <name>A0ABR1X9P3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit GON7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PG997_000070</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GON7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674158.1">
        <property type="nucleotide sequence ID" value="XM_066804385.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037445"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014849">
        <property type="entry name" value="EKC/KEOPS_Gon7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08738">
        <property type="entry name" value="Gon7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0779">Telomere</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="60"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK8093385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="133" mass="14422" checksum="685936FF83675535" modified="2025-10-08" version="1">MPTLTTHSEAPHSDPFTFTTDLSLDHDGPEATLTTSQKSAYLARLRAAVADHQSRINTALTARMETDKIRDPSSAPAATTEPTSNKNKKRKKNGNGSGADTPQQKKNAAAIMADEDAEEQNYGEEVVEEHDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9R9</accession>
    <name>A0ABR1X9R9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C-x8-C-x5-C-x3-H type zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674159.1">
        <property type="nucleotide sequence ID" value="XM_066804386.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037446"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057683">
        <property type="entry name" value="DUF7923"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543:SF1">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25540">
        <property type="entry name" value="DUF7923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7923" evidence="2">
        <location>
            <begin position="49"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="398" mass="45186" checksum="97721370C3AC9C76" modified="2025-10-08" version="1">MADVEMSMDIASGYDPLAVQAEYNNYLNMDESRNKFILARYLNDDYIDDPFVAVVVEGDGAIFTDELLKNPAQAADKLKAAVRAQLLEMPSLPISIPIVVRIYANLHGLAKTVAANSIIDYNDMAEFPSKFNFECDYFDFVDVGRSKEAADSKIRCKRIFLAGVTHDAGYLNDLKEFKGDQGDRITLVESYPDVFRTEMLPSQGAPKPRRQSQEQTAPPLQMDHHGTGNDAALMRNDGYPRPSERVSKMNDSTGSFYNRSHVRIDRILKHPGNRNEPHQISFVRKKNGRQGFCNDHYLGGGGCTRTDCKLINDVVLEPRELDILRYLARLNFRCYAGPKECRNMACYKSHTCPYPKWQCPNKECNYAVHLGADPEGEDRKAKYVLFEDYDTEMIELED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9X3</accession>
    <name>A0ABR1X9X3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonuclease H</fullName>
            <ecNumber evidence="3">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_000079</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674167.1">
        <property type="nucleotide sequence ID" value="XM_066804394.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037454"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13934">
        <property type="entry name" value="RNase_H_Dikarya_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="8">
        <location>
            <begin position="34"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8093394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="272" mass="30529" checksum="9DC26F26FB112BBB" modified="2025-10-08" version="1">MATRFSLEEHVGRPLDDDESVELPMVLTCLADDPNHSIIVAVDSACRNNGRPDARAALGVFFRADSKWNRSEVLPPEDATSQRAELCAALRALELIHQAVAHEWEASITCGYPLKRVILKSDSSYLVSSMTEWIFGWREHGFTTARGKRVQNRDLFTDLLNWIGLLDDIQIQFWLVRREHNRDADGLANAALDAAPASATLWDPRDAVNQRRLESDSYASERVWRWHNRMGHVPLHALQHATLGAARGMDINFEQIQAEFDKGAKCPSCGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XA62</accession>
    <name>A0ABR1XA62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extragenic suppressor of kinetochore protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000250</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674338.1">
        <property type="nucleotide sequence ID" value="XM_066804565.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037625"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007587">
        <property type="entry name" value="SAPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634:SF8">
        <property type="entry name" value="FIERY MOUNTAIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634">
        <property type="entry name" value="SIT4 YEAST -ASSOCIATING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04499">
        <property type="entry name" value="SAPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="70"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="427"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="911"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="479"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="554"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="571"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="587"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="624"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="634"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="921"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="937"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="974"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="989"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1005"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1027"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1043"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1091"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1117"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1140"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1162"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1192"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1209"/>
            <end position="1218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8093565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1218" mass="132070" checksum="1E2B89F0EFB9CD79" modified="2025-10-08" version="1">MFWRFGGYANISTIDTILDKQDFQLEDLLDESDLIQELKQHNTKLIEYLREEKVLEKLLEYVVAPKLEPVENPDEEKEEEEKKGKSRLSFGRPRASSSATNDGEAAEDEVEKKRNRYAYVAAEVLSSDNWSIYEALMESTSLLRNFWNFLKLPAPLDPLQASYFTKVNESLFDKKTEEMLDLLKSLDGAVADMLRHVDCPMVMDLLLKIISLERTESGQGVVEWLYTKDVMPTLLSFLGPEHSWATQTSAGDFIKAIITVSANASQNEQACIGPNELTRQLVSKDCVEKLISYMLGGGNPLTVGVGIIIEVIRKNNSDYDPDVGSDNNAQPSSRDPIYLGNLLRMFAEHVPDFMNLIMHTPAQKQRLESTFGDKIEPLGFDRFKTCELMAELLHCSNMALLNEVGSEQVIAVRDEERQRLRAEGKLVMNRGDDAQSSAEDLTMRGRHSSPDDGRRLEVTNASDDDGFEEVAPSGEMTEDTSHEFVKAEDEILPPASSASFLDKDDEDFVDEPLSSPRLNVHDNKVHEQEVPEFENPELVVAPLSPRKAPIKMAASSTEGDSSVTSVDEPTSEAQPPTAPAETTTEATSEKKSTSEDASDAKKDVNPTPDNATSAPEAISESKTETPSSSSEPTPSDKSDEDKPAESTKDESTANSTTTPAPVPPTKTDEESIVVGHKADASEAPAAAAAPEEPVEPVVGDFLKMQFVKHQVVPTILTFFFKYPWNNFLHNVVYDIVQQVFNGPMDRGYNPTLAISLFEAADVTNAIIKGQVASETSQAQNKTRMGYMGHLTLIAEEVVKFTERNPPELLSELVLDRVMSQDWINYVEGALAETRERDNAILGGVRPEVAMSNRAAMAGNGLGGMGLSSLGLGNAQGGSNALAEAGLNGGATAEMPDNGSGSSLGPFSISSGLLGSGFGSSSDEDEDESEENEEDVNNEVSDPSGAAASETGGGGSGDFRAYTDPLNASSSLDPPSIPPPPPPPPPLNIPPSRARLQLAARLAMHQKSSVATSSQSAEIENGDDDSDELKLTREPDSILRDPFGDDAEEDDIDSDDGLGEGGDAGSWNQQARGSWWRGALSRRSNEKFGDGRDDDSDSEKDEAAEDDDEEFGDFAMPEVEKEGESNEKANVIVKPLPLHPPNQNQKTSAFTSLWPFSGPGFGSKEKEKEKGKGEEGGSSGGEKAASSEVTGDDGGKIKSTHEATSRTSIEDPDDEEVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAQ4</accession>
    <name>A0ABR1XAQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000443</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674531.1">
        <property type="nucleotide sequence ID" value="XM_066804758.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037818"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15398">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15398:SF4">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN 8 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="141"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="297"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8093758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="343" mass="37916" checksum="FE5C4ABEE9D6A593" modified="2025-10-08" version="1">MEMTGYFDVPSPSYEPLSPPTQHAQLSKASTQHSGKKDPRKGMQKIDTAATRPKSRLSQSSQIPHDIEDDHDTPSRAIKNEEATPKAFDDMGGEGGLMIPRSTKRKREESPEEAVSSEPPTHVLWTRAFHRVSAQALEQVTSHKHANMFAGPVKVRDAPNYSDIVLQPMDLKKIRAAIHQGQRHAQNVEKTQSDIEPSAMNVWLPTTADLVPPRGIINIAQLERELVHMFANATMYAPDPDRGFGPEFIKKRGEDDSDDEEGVLGYEVDENGIVKQTRNMFMEVEKLLGDLRSEVERNAQPAGVPPLSRSVSMVGGEATAGEEDDEQGGDDAPSVAKRRRVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBD2</accession>
    <name>A0ABR1XBD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytokinesis regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674773.1">
        <property type="nucleotide sequence ID" value="XM_066805000.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038060"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034586">
        <property type="entry name" value="Bfa1/Byr4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35140">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BFA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35140:SF1">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BFA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="959"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="540"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="687"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1037" mass="113734" checksum="464F03596C1D77FA" modified="2025-10-08" version="1">MNFANPSRRSPSDSSRRPDAPDSGRPAGLEPENRIPDHPHRKCAWAVVIVAEEDMTPWLCTSNIELHIWAPVEEEVENWDDDDFMIDDDLTFGNGSTTGHGHRRDSHNSFRSDRESLGGDEERLLHLPGDDEKSTLDAIAAVTNAGIPIPQNVPPSALVGGTIKRLGERSSRKSTKKIGAMTWSYRFPETLRQVSGGSSAAPSPVKSASASFTQDTPLWDSPPKQLGSPMHMDISPKRLAPPAEISPTKKKLITPVDLDRFRDNEEDDDVFGDGESTIKASKLRAPVSMRNISLISQQPTPAKVEETDDFEADLELPSHGKLNLSSRRDIPRTPALSSGDELDWCEGSLGTRFGGTRRDAFSNRSSSASALSPSIASSITAESEDEALDGIVLPNGPLDLTERLKRRKQSRSPERELDPKRVCPSKDSPPETPGLDKGDDLDGLEIGDGDVFGSGKTSMHRNVRLKDTRPMSPARPKTAVSITFSNKPVSSLPTSRLPRPLGHERSLTQSSLEPVSESGDPIPSRPARRPQSRLGHSNQSSVSSLHTPTTPSSTTSSLSPATPRRRELGQKPSTTTLRNEPTTTNAQLLRLKRSLPVLRGAPQSSARPLSGRWDRPPSRDRPTSSLGPKTPVERARPSPSYEGSAAQARKNSAPFLPAGASSTQSQHVSSKFSRNLRRHDSDVGPDIRPLSRTFSSSSIRSPSPRRFRPVEKMAAEPWHNLNKPRRVRQFGDGSELDAFDDLPTSAQAESKYEKVPSGSGNRTNIRNKLHQNVLPGRSTPSPVSPFTPAKPDNLPHFARDTAASRMAREASLANRAPQNGPLGPIASQRLGHISTRGNLHPHSHHSGTADSKVVNGMTYNPDTYRWEGNDTALNAFEVPASSPSTASLSQSVREKEASTPRPMLIQAMGSSKGVRRVGDMIFDPDMFTWHKVDPNTTPTMARPGDPMDIVEEDDDPFKDIPDLEEKEAEGGEGGPGRVSEMHDDWLVGEEFDVGPEFVRRQREEEDRWRKKCEKWVGTVNRDNNAWRWAIRDIVTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBG2</accession>
    <name>A0ABR1XBG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674759.1">
        <property type="nucleotide sequence ID" value="XM_066804986.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038046"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="168" mass="19170" checksum="462426A76E709666" modified="2025-10-08" version="1">MSLPMLKDIIPLAFGCGLRWQTEPYKSQDHDAWVYRSLLSSKYSKPLVKGLKAASQRTDGQGIPDLEKRTTSNFFAQIWNEAAQNVAHCKGMPPRAFFKACKEKYECASTVPNEAFYQFTMRAINARKIFEEFQPGWKRSGGTSMSNAIVNFIDAFSNEYDIRYGLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCI5</accession>
    <name>A0ABR1XCI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675123.1">
        <property type="nucleotide sequence ID" value="XM_066805350.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038410"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046381130" evidence="1">
        <location>
            <begin position="17"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="194" mass="20560" checksum="732DAE275C6C621B" modified="2025-10-08" version="1">MKFFGPLTLAIGLVAAVSPASQEASLKKARIPSPAPLKYIMSMVEPAIKRDMSGLTSLPEGLTSRTSSHVSQVASDAAKRQLSKQDFYECQASNPPPQPSDCNTVINQVQASNQDFILNEGTCLAFTFSTCTGYFCSLCGQLATHTDFIASQFESVQGLCVEGGQAGTIVGEDAPQYETGFLRAGSGVPTYDVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCI6</accession>
    <name>A0ABR1XCI6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001101</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CENP-C/MIF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675189.1">
        <property type="nucleotide sequence ID" value="XM_066805416.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038476"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028386">
        <property type="entry name" value="CENP-C/Mif2/cnp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025974">
        <property type="entry name" value="Mif2/CENP-C_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028929">
        <property type="entry name" value="Mif2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684:SF11">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11699">
        <property type="entry name" value="CENP-C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15624">
        <property type="entry name" value="Mif2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mif2 N-terminal" evidence="7">
        <location>
            <begin position="21"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Mif2/CENP-C cupin" evidence="6">
        <location>
            <begin position="540"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="447"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="191"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="351"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="477"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF15624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8094416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="641" mass="71229" checksum="43E4E3262DB04414" modified="2025-10-08" version="1">MAPRQATAQRRNQSSQNEGQIFELGVRGRKTGVTLVDTGERDEYGMEPVDNLFSSPDKGQMAPPMGKSQLGPATVSRMRKSSQGRLSIPRARSPVKTHLNSPARHNTHVAPGSSPTRGSIVDDRAESPSSKSVKRRLNFSADPTLQPPTNGNSKAKSSGSQSGRSVNRLPLSDDEDDLPRRSRPQKQQEPVQEEAEEEEDEEEEDEDEEEPMEVLDMGDDDGDLEPPAPEEPEMEDESGQQQDEEDEPTEEVSIEQEKPEPKKRGRKPKNKGTVSPQPEAPSAEPQEAPAKKQRGRPKRDSVGTTQEPAPKKSKRRSDEDEPEVAEAAERGTKKARKEKEKPVKAEEPKVKGKPGRKRKSSGVGPASPAVIPRAPMPKSRGLQILRREGLNEGNIRTTRSGRISTKPLDFWKGERYEYETDNEDLVPDKGGRHIKLATIKSVVRVEAGADEPKTKRRGRPGAAGGARGRPKRRSVAEEEEEEDRSDWEDDPGRIVGECILWRPEYEMEPPEGEEQVEVMDEEIAVSEAAVQMKDIKGASFQFAKTLTLPFFGSGIVDLPPHSEKKAKNSRKMQMVFFVHYGSVVVNITQTQFRIGKGGQFFVPRGNHYSIENNTERPARIFFAQGCEMLLSPEGEEGVSMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCJ7</accession>
    <name>A0ABR1XCJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fungal-specific transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001092</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675180.1">
        <property type="nucleotide sequence ID" value="XM_066805407.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038467"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF40">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="73"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="247" mass="27876" checksum="84D5E27399C6793C" modified="2025-10-08" version="1">MASILCSNSKARFVEDQDDPEEYMSSFCGTQMRWESLGILFTYWAFSASLTRDTDIHPVGQNVFTGRQMSRQFTNCVSKCIDICRKLGAPPNTLFVYVCFRHMLLESNVSGDAKLVAITTFLGLHCIPRTTPYEPSISSEIKRRLFACVYNIDKVVSSFTGRPPLLNARHVSTPLPLDIDDEVLLGDRARLLEVARTPEISDERHFYDNKLKSVTIMRARGMMAFIRNDILDISLGQIHGDVAASLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD22</accession>
    <name>A0ABR1XD22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal protein L3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675368.1">
        <property type="nucleotide sequence ID" value="XM_066805595.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038655"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1460.10">
        <property type="entry name" value="Nuclease A inhibitor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056539">
        <property type="entry name" value="NuiA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42093">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42093:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23151">
        <property type="entry name" value="NuiA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="167" mass="17986" checksum="EAEF18E94D3979A6" modified="2025-10-08" version="1">MASDEDYMAFLDKANKDPNEGYAKPASSGGAKLEFKATGHGAQVPAALKEATQDAFYVSDADEPFVPVSLKWDEGGKGLPNEEEFATLIGHPNPSSANVELQDPADWDPQGQYNKILEAVRKAGKGNDVRVYKVPKDSSRVEYWVVTTEGKGKDAKLVGVKALAIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD88</accession>
    <name>A0ABR1XD88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arabinanase/levansucrase/invertase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675401.1">
        <property type="nucleotide sequence ID" value="XM_066805628.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038688"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925">
        <property type="entry name" value="GLYCOSYL HYDROLASE 43 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047089490" evidence="2">
        <location>
            <begin position="19"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="451" mass="49306" checksum="4004D3D43ECB2639" modified="2025-10-08" version="1">MKTILLLSTFLISRTVWGASWIVPGAVWYDTAGKKIDAHGGGVVQRGSTWYWIGYSASDRTDDWSIEDQTPLMYQSTDLVNWENLGEQAPSVTGMWRPKFASPNGSSFWLYGQQDRNVLSLSSSQFVGGYSQKAKGLLPPNKYSYSDTGMFFDKATSYLMGLADCQGRLRSPRHPRIRRHLLPPRLGQDGLPRQCEPGLLGDVPRAGPWTGPSDIAPPTEKTYGSQNTYAFAVEGSRATTHVYMGDAWDSKGSAASNYVWLPVAIDAGARTVALQYHAMWKVDPGTGVVSFPATRKRYAAAEAEKVAGRDGAVVPLAAKRCLSDDNVCAAAVPATNGDNNNANQQRTKTHRLRTGDEVTFRNVTGRPGTPHEWVSVRYTVNDPDAGEAYVKVNDQTAPVNLSEYNSRAGYHHTVPVRLRLDEGDVNTITLGAVGAAGFEMEVEGLELHEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDN5</accession>
    <name>A0ABR1XDN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001367</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675455.1">
        <property type="nucleotide sequence ID" value="XM_066805682.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038742"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF17">
        <property type="entry name" value="O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="261"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8094682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="425" mass="46434" checksum="9D23AF289FD42624" modified="2025-10-08" version="1">MGLDITNGTNGTNGANGGGAVVDKSVATNPNNMDAVPGLVKQINAGVDALGTGGDEARHALLVKARNLMQALETPRETMIKHCWAQTGAMAGLTTGVDSGLWDLMAKNGDKPQKVGELASTLKMDTVLLGRLMRHLGAMGYIVETGEDEYKPTNFTNSLTIPIINGGYYAMLAASAGVISFHEFARKTDWQNPTDAGRTSFHQAYNTDKNFFEYLQAVGYGTQFNDHMGGYRQGRLPWMHPSFYPVQENLIDGAETAADAPLLVDIGGSVGHDLAEFQRFFPVHPGKLILQDLPVVIGQITDLDSRIVRMEHDFLTEQPVKGARAYYMHSVLHDWPDSLCQKILAPLTAAMRPGYSKLLINENVIPRTGAYWETTALDMIMLTEFSSRERTLDDWQNLLGSSGLRIVKIWSGGKGVESLIECELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDP2</accession>
    <name>A0ABR1XDP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001363</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675451.1">
        <property type="nucleotide sequence ID" value="XM_066805678.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038738"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="343"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="473" mass="52188" checksum="F1C7E47A67EA47EA" modified="2025-10-08" version="1">MSNPQEERSEPFRIAIIGGGIGGLFCALSIHHHHHHPNISSSQDDHGKSKRTIQIDVYEQAPQYREIGAGVGIGINAARLLHRLGLGPGLVQIAGRRQGTWFAFRRHEDSAEIVSVPDAEAEPGDIRQSPCARSDLLELFLAAIRERGAATLHTEKACAGVSVLNADGEERGGGGGGRVHLQFRDGTTATADLVVGCDGVHSVVRDQFVTDANNKSVESGMIAYRGIVPTAALAPDWPFAHWSNIWIGKHRHFLSYPITGNTKLNIVAFVTKRLGGGRLIGDSEDEANKYKNIRESWSSLCDRDEVVADFEGFDEPVQRIIGLMDERPGRWRINDHEPLARWHFAGGRVVLVGDAAHAMLPHMGAGAGQSVEDGWILGRALSEHLSGSSNEKFQSLESTMQFYQDLRLQRAQKVQAASRVSGNLYELQTEEMSRLSYEDSLPVLAESLRERMKFVWSEDIDDSYSRMRDEEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDU5</accession>
    <name>A0ABR1XDU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675615.1">
        <property type="nucleotide sequence ID" value="XM_066805842.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038902"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="119" mass="13086" checksum="7FBF573F6DE67800" modified="2025-10-08" version="1">MERPSQPRYAQVAKTQPQPQAQEPRPPWALLRLGLRKKPVRREASPPTSKNQKEAEASTSFTHAPTTSHIESHQQSSSSSSHASDGKPSLEPSSTPICDELFQFPLPAAPELLRGVKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQN7</accession>
    <name>A0ABR1UQN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660649.1">
        <property type="nucleotide sequence ID" value="XM_066819764.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052824"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="60"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8061229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="649" mass="74567" checksum="20F0F9FAD241F893" modified="2025-10-08" version="1">MTTTILSVGLSSTNTSPAEPVSPGWLGAGVSVQHNAAYQCPYRATRRVHWRPDSRIRNPLSHTWGHEEVTFEDWKNVDSCREKRGFQKIWNACQQTKRDELQYLWCDTCCIDKASSSELSEAINSMFVWYKKSTICYAYLEDVFSVAKEMPSSRWFSRGWTLQELLAPNNVQFFNVHWRSLGNLAYPEYAYDSDGPISRPSDTELAHFISIITGIEEEYLHGRPISEASVAQRMSWLSKRTTTRIEDMAYCMLGIFDINMPLLYGEGAKAFVRLQQEIIKVSNDHTIFCWRWIPGIVPRDWASLLAPSPEVFQESRHIEQTPAQAKEEISTYSMTNAGLSIRLPIMLTFWYQLATLKATNSSSARLAVPIKISPGQNTFARYPFPPFPVPVPDHTRETQHFYIGHKAEYPFELGASGDHRHAVLMSWNEPSLRPFLGDTEWTPEWASREIRDLPPGATRWLTYWSSNDGMIWHCHWDYERSLLALEWDEELNCSYGIMGLQFPVNGLGEIKNRECIHILFCAREGTIGRGAEFCCMELEGRINPKAWVLGEEDVINDGTWRPKAWFDNDVEMLIKQAVRELRASSQKSHELLIPQRPMQSTGAESPQPPSETKEAVRLLMERNNQFQYTETKEFGKGITVQMALLHRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT10</accession>
    <name>A0ABR1UT10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Quinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_015381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660580.1">
        <property type="nucleotide sequence ID" value="XM_066819695.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052755"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051603">
        <property type="entry name" value="Zinc-ADH_QOR/CCCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44154">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44154:SF1">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="10"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8061160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="375" mass="41263" checksum="94584DE67B506EA8" modified="2025-10-08" version="1">MRAIGVSQYGPTDNLQSQEIPRPPAPTGRQMRVEIKAVSVNPIDIKVRAGTYDDPPDYYDRVRGLTEGKCDDASSSGNSKLHVMGYDGAGIVRELGPDVRHFQAGDEVYFLASPVLQGTYAEELLVDERHAGHKPRSLDFVQAAAMPLTYGTAYESLVDRLGIRPGEKAGILIINGGGGMGSVASQIARRVLKLPVVITTASRPETAAFSRDIGGATRVVNHRDDIVRQIRELREKGEIPADVPLKYAYITSRTEQYVAPIAEVLAPFGRVCSIVQARFGMYGTQFMSKSLSFAWCWIATGPYHGYDNDREEKHHEWYEELAKLLDDGTIKCHLTQRRKLTLENIREAHKATEAGKGVGKTALGVDESGEQQAFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVF5</accession>
    <name>A0ABR1UVF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661496.1">
        <property type="nucleotide sequence ID" value="XM_066819308.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052368"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF1">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="25"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="299" mass="34435" checksum="9F66F9510F66CA5B" modified="2025-10-08" version="1">MGVDPIEIPWDLPSFRGSFTQVDEFTPFPRLPAEIRCKIWQAACTPRRFSSSPCDATRKWTRKGYRRVVAPLPATARVNQEARAETLRVYSKIPNTTSSWDISGFINYEVDTMTFSCYGPSYSARELPWAILQNLQRITIVPKCWVFGCQPTRTDLNTFDNFLCYVATRYFPKLRELDIDLSPQLERGGKSFLSAPRRAAPGMSCSFRPLFFRTVDGHGLQFLPTTNYWGGWDSIKILIMEKHEADRYGDGKDPSKHKVFIDHLGLCLWHVFLPGGFLLDDQEVDQLMGDHRYTIQSQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVQ6</accession>
    <name>A0ABR1UVQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661351.1">
        <property type="nucleotide sequence ID" value="XM_066819163.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052223"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="56" mass="6216" checksum="E3A549F7A7BC5A62" modified="2025-10-08" version="1">MDTISRPIASVEVLRCMRCARSVEATSTDDPASTGMVRVGHNIYYCDRCAKMVGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UXI2</accession>
    <name>A0ABR1UXI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">60S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014847</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661349.1">
        <property type="nucleotide sequence ID" value="XM_066819161.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052221"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_uL13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="22087" checksum="87E141EBE4B0C737" modified="2025-10-08" version="1">MSSFESVVVIDGKGHLLGRLASIVAKQLLSGQKIVVVRCEALNISGEFFRAKLKYAAYLRKMTRYNPTRGGPFHFRAPSRIFYKAVRGMIPHKTARGAAALQRLKVFEGKKMVVPQALRVLRLQPGRKYCLVGRLSHENGWKYKDVVERLEERRKAKSAAYYERKKLAQRQLSEAKKNAKVDDKTAEALTNFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1N3</accession>
    <name>A0ABR1V1N3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_011849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661856.1">
        <property type="nucleotide sequence ID" value="XM_066816164.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049224"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="135" mass="14678" checksum="A86BED6041FE53F5" modified="2025-10-08" version="1">MDVFHPYPRLPLTSVRPHGSTSAWQVGPYGKAGAATPESLSAFRSSAVYQYRECPCDDEAACPRTAPAGWIRCRASCPCSAAPDALPGRRGPSAHLGHTPPMARPLSLLPSLRRLEIRFLADLEREPPSQDNSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2G8</accession>
    <name>A0ABR1V2G8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">26S proteasome regulatory subunit 6B-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012133</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662139.1">
        <property type="nucleotide sequence ID" value="XM_066816447.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049507"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="198"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="421" mass="47023" checksum="585677E4845F8942" modified="2025-10-08" version="1">MGDVAVENPANTVAPHNKPTPSTIPNVENIEGLSSQGDDEYGTLKKLQRHLEYIQLQEEYIKDEQRSLKRELVRAQEEIKRIQSVPLVIGQFMEAIDQSTGIVQSSTGSNYVVRILSTLDREKLKPSSSVALHRHSNALVDILPPEADSSIAMLGADEKPDITYADVGGLDMQKQEIREAVELPLTHFDLYKQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTTANFIRVVGSEFVQKYLGEGPRMVRDVFRMARENSPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTSNVKVIMATNRADTLDPALLRPGRLDRKIEFPSLRDRRERRLIFSTIASKMSLAPEVDLDSLITRNDPLSGAVIAAIMQEAGLRAVRKNRYNIIQVDLEDAYSSQVKSTSDENKFDFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V339</accession>
    <name>A0ABR1V339_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012353</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662359.1">
        <property type="nucleotide sequence ID" value="XM_066816667.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049727"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855:SF11">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN WDR12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855">
        <property type="entry name" value="WD40 REPEAT PROTEIN 12, 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="187"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="31190" checksum="AE4F645285388418" modified="2025-10-08" version="1">MDQTVRVWKYKEGSDKLSGDLKPTLELLGHKGGIESMDVHTPSSRILTASNTGEIGLWTTSASAAPDAPESALLQANPAKKRKVSVSSGVQKGALSMMQIHSGPASAVVFHPEDSTAAYSAGQDHTIRTIDLTTSKVVHSLTTAHPLLSLCSVQGISTPLLAAGTSARHITLVDPRVSATTTSVMTLRGHRNFVTSLSASPMDNYSLVSGSHDGTCRIWDLRSVRTGSKAEGGGSVSEAVYIIERESQKGQKKKSDIPGQGCKVFGVAWDKQWGIVSGGEDKQVQINKGSDLLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3P4</accession>
    <name>A0ABR1V3P4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012550</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662556.1">
        <property type="nucleotide sequence ID" value="XM_066816864.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049924"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039927">
        <property type="entry name" value="Ribosomal_mL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="7">
        <location>
            <begin position="32"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="137" mass="15194" checksum="D2102C9A36F88A5D" modified="2025-10-08" version="1">MTIRALEKISVGQNGIGSFILQCKRLDIHYCDHSGSSRGMNAFIKTHLSKFAQTHPAIEFAVSPRPRKHPVMIGHYINGRQKSICVANMEPSQILKKAELLRDASGDKVKRVNKPVTSVNESVRGIWSPYHGNGMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V480</accession>
    <name>A0ABR1V480_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_012748</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662754.1">
        <property type="nucleotide sequence ID" value="XM_066817062.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050122"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF385">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="165" mass="18117" checksum="0CBA687D66AAEECE" modified="2025-10-08" version="1">MSKVFFEVEWEEQTGRINFNLFNDVVPKTAENFRALCTGEKGFGYKGSSFHRIIPEFMLQGGDFTRGNGTGGKSIYGEKFADENFTLKHDKPGLLSMANAGPNTNGSQFFVTTVVTSWLNQRHVVFGEVADQASMDVVRALEATGSQSGTVKYNTRPTIVNSGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5E3</accession>
    <name>A0ABR1V5E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cleavage and polyadenylation specificity factor subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cleavage and polyadenylation specificity factor 100 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013152</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663158.1">
        <property type="nucleotide sequence ID" value="XM_066817466.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050526"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027075">
        <property type="entry name" value="CPSF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025069">
        <property type="entry name" value="Cpsf2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922:SF1">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13299">
        <property type="entry name" value="CPSF100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Beta-Casp" evidence="6">
        <location>
            <begin position="253"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="586"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="586"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="626"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="652"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="885" mass="96059" checksum="50F1AF0DC41F7A01" modified="2025-10-08" version="1">MFNFTSLQGARSESAAVQSILELDGGVKVLIDVGWDESFDLHNLKELEKQVPTLSLVLLTHATISHLGAYAHCCKHIPQFTRIPVYATTPVISLGRTLLQELYASTPLAATTISKDSLDELSYSYNSQLSSSESNILLQPPTHDEIATYFSIIHALNTLGGTIWHIQHVYAVDWNQGRENVYAGAAWLGGAGGGGAEVIEQLRKPTALVCSSKGATKPALPRSKRDEPLLETIQSCVANGGVVLIPVDSSARVLELAYLMEHAWRKNAVAGGKLQSAGLYLAGRSIHSTMKYARSMLEWMDERIVQEFEDVADGSKKTNGTGDGGNSGKQGGPFDFKYLKLLDRKGQVDKLLAPKANGEDSVGKVILASDSSLEWGFSRDAFRALVADPKNLLILTGLPAQPAAGNAALASTFYRWWRDAVVEKEQQGADISRTGVGADGTLIQVRGEGREAETRNALRQPLEGDDLAIYRFWLAQQRQLQDTVQTGAGTALESSSMSMMSHPNSETHQQGKALNVATTLGRATRKKAALADEDLGANILLKKKGVYDYDVRGKTGRDAMFPHPVQRRRADDYGEFIRLEDFVKAEEREEDTRDGEPTGKNDAEANLGQKRKWADAAPNKGQGPNSDKRPKLERNVSDDHDKVVVDGPLVGELDDVPDEEEDTSTGPYKLAVTTEKFTVNFNIAFIDFSGIHDKRSLHMLIPLIQPRKLILTGGGSEETDELAADLPQLVTQNPIDIFKPDIGTSVDASADTNAYTVNLAPALVKSLRWQDVGGIKIATLVGRLTVADESPVLDVPATVAGLTASHSVTPFHVGDLRLANLRKDLRDSGLSTEFMGEGTLLVQNAVIVRKAATAGRISVEAAGWETDTVQKVRQMVYEKLAVVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6A3</accession>
    <name>A0ABR1V6A3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_013483</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYG1 (TC 2.A.94) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663489.1">
        <property type="nucleotide sequence ID" value="XM_066817797.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050857"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14447">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14475">
        <property type="entry name" value="SPX_SYG1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF103">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 53 MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="497"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="536"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="715"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="759"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="9">
        <location>
            <begin position="1"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="8">
        <location>
            <begin position="646"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="37"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="268"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="841"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="854"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="871"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="895"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="922"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="935"/>
            <end position="955"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="978" mass="110607" checksum="893D45EAE33B2A2D" modified="2025-10-08" version="1">MKFAKELEQDLVPEWRIKYLNYKAGKKYVKSVTRAIAKANATPSGRRGELRPRRTPTSFQNRVTPRPDTGLESRQADEGPGPVHAASARPVAMTRNESQSLTKSPGNAGNYGSFVPTPPSQSPLALAATNSHKNAFALPGPAIDEPAAGSSRLTLQRSLSMDPPVPINKRASTVPDPSPLTRQTSSMRMRRLFSSGTGDVGGNDGDRDVGLYALDTVRQREQEFFDFLDGELDKVETFYKQKEEQAGQRLAVLREQLHEMRNRRANELAEVKQRKKGETGNGNGHLLSSNGEGGAQGWMDPIKSKIFKPGPNSTALLKMPRTPVFNGRSAESGRDYVKKPHGDDVPYRTAKRKLKLALQEFYRGLELLKSYTLLNRTAFRKLNKKYDKAVNARPPYKYMNEKVNKAWFVNSDVLDGHIVAVEDLYARYFEKGNHKIAAGKLRRLTRRPKDVSGNTFLNGLFIGTGAVFTLQGLVYGVELLFDPDPIVREQTTYLMQLYGGYFLMLYLLPCSVATNKINYPFIFEFDPRHHLDWRELAEFPSFCLLLLGIFIWLNFTRYGSPDMFLYYPVLLIFFTLVLILLPAPILGHRSRKWFAYSHYRLLFAGLFPVEFRDFFLGDMYCSLTYATCNVELFFCLYARSWNDPSQCNSSHSRLLGFFNAVPAIWRAFQCIRRYADTKNMFPHLVNCGKYGMTILAAVMLSIYRMDDTHSNLALFVTFSTVNAIYCSIWDLLMDFSLLQPDARHNLLRDILALKRRWPYYFIMVVDPILRFAWIFYAIFTHDTQHSTAVSFLLGFAEVTRRGMWALLRVENEHCGNVAQYKASRDVPLPYHIDHEPLIERPSSEESVNEPPLPAQQQQASSTAPNELVPVATAETTASAARTPDEAGLRRRRRSEVRPGGESIRRIMAEAHRQDFEKKRRPAAGASAADVGQAGEVDDIQSEDGDDDDDDDDDDTASVLNERLEMRGADGMVKNNEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6J2</accession>
    <name>A0ABR1V6J2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013570</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663576.1">
        <property type="nucleotide sequence ID" value="XM_066817884.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050944"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF6">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AN1598-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8066823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="376" mass="42504" checksum="E5C5B8EBFCE795AB" modified="2025-10-08" version="1">MSVMFERLDFQLIHVNQLLHALPQVAILVALLGMAVIASRSRKYGEFDIVGDKKDLRAALRKGTELYPTSGFAIPTSPPLVILPLSMIDEIKSLPDKKVSTAPELFKRAGGHYSKLGTNASAAIKALRIDLRRRTTTIPHLTEEARYAFDDALGTYEEWTPLAVFPKINRAVAIVSGRVFLGKRLSRKEEWISLSSEWAVHIFGIMRAIQRYPSWLRPYITPYLSETKHVLAHRAKAKKFLEPTFQKHIEAKANKTSVPGEEESLASWLMKYIAPRHNTIEGLTRHQMSITWASIHTSTYALTQILFDLAANPEYQDILREEIEEVFSNGSTEEVLESDLPKLAKMDSFMKEAMRLNPNTIGKYTSPALSLRLEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6N9</accession>
    <name>A0ABR1V6N9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD/NAD(P)-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_013613</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663619.1">
        <property type="nucleotide sequence ID" value="XM_066817927.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050987"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8066866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="422" mass="45975" checksum="C6672114A6E0E1FA" modified="2025-10-08" version="1">MTESIRIAISGGGLAGASLVHALLQYNHLDVHIFEEAGAAIGVNRAALTALDLIGPSAAQSLQNAGAVPQQSVRFMLAQGDRPETQIDVAKEHFPGHRLTNIAHRAAFLRELLSKVPPERMHASKKLERVERADYGDGGPITLHFADGISHECDILVGADGIHSTVRKIILGEDDAAANPRNTGWWCIMALKPYEEARACLGDGYVDVNDASEYGWVGDGTFLMHNVLSGGTLVQFVVTGSDDPTKMSSQWNRMVAAEEVRKLYAEWPPRLRNAVEKLLCDKAEQPAIYLWEHPPARTYVSGPICVTGDAAHATTPWQGSGAGMSIEDSLILSTLLGQAKNPKQACAGLKIYDKLRRGRTQQVVESSRGTGVILTGKGEETGLELEKLRKNALPRWDFIVDFDVKKHREEAVEMMGRGWGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7S8</accession>
    <name>A0ABR1V7S8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_013994</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664000.1">
        <property type="nucleotide sequence ID" value="XM_066818308.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051368"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="485"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="530"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="893"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="929"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="996"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1051"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="277"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="615"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="893"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1130"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="569"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="806"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="577"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="806"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8067247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1370" mass="149078" checksum="676BA238E16206F3" modified="2025-10-08" version="1">MSCPPAIDDVFGPAVDECARTFDFTLLFEETILSILPSTVFLILGAIRIATLFTRKSRVGGVILRSIKLVVIGVLLAFSVALLTLWAVSDGSSSQRTRATVPAAALSLVDCFAFMALSYMEHGKSLGPPLLMDTYLLISILFDIVRIRTLWMAGTSTAISALFTATMGLKIGLLALEEIRKDRWLGPETKQCGNEITGGIFTRTLFSWVNRMLWRGYSTALSVPTLQDVDPSLLSPSLWNKVCKPVETLISGDERSLLVAVFWALRWQLFAPVFPYLMVVASQLAQPYLIRTILDYLGTAYDGSEYQNNTGYGLIAAYGLIYICIAVATAWGQHLSYRFTVMLRGVLVATIYRRTLSMSLSVAEDATALSLMSTDVERIVMGMVHIHDCWSTIVQVGIAMWILYTEVGAIFIAPISARLRQLDCPVFAGAFQASWMEVLEKRVAITSSLIGSVKSVKMLGWAKRSTELVQQLRLAEILSARKFRLMLLGVVTVSFLPVTLAPVLTFGVVAAQSHGGSNTILGSNRIFTTLSLLALITQPLDLIFAFVPEILAAVACFKRIENYLRQKPSSASASSSDQTHPTASHETLSHKSSVDGSNADGYASSEKPLPAGEAIRLQDAAFGWSKDAGPVLRSLNLRVPAHGLTMVIGPIASGKSTLLKGILGETPLRRGVVQVAACAGGRFSHFDPAWYGTVIRACALEEDFQQFPEGDQIVVGSNGLGLSGGQKQRVAIARAVYSKRDLVLFDDVFSGLDMHTQSHIMLHLLDHADFIVGLDSNGSVVENGPREDVTKKHDYLAKLGISPVKDERTAQGTPDKPKETDPEPAAAIPDSLQRTVDEETQRLGDGSIYKYYFRTFGWPKTFVFFALQTILKSSYLGGGAANDAEPNKYNGRYLGIFTALEMMALVALVLTCAHVLLNLAVISGAKLHYTLLTTTLSAPITFFSVTDIGSITNRFSQDINLIDAELPFSLINFVTNGLTSLAQALMIIPASTWLLIGYPILFGVLGQFLETLGGLATIRAFGWQEELILRADERLDASQKPFYLLYSIQRWLNLVLDLIVAVVAIVLVAIAVSLRSATSVGFTGVALFNIMTLSAALKSAISSWTLLETSIGAVARQQTPPDNWPTTGAIVFDRVTATYKDDDEDDAETKPAISDLSLTIKHGDKIGICGRSGSGKSSTLLALFHMINYKGSIAIDGLDVARMSRETLRERLTAIPQDTVFLAGSVRLNCDPRGRASDEEITEALRAAQLWDAIEAKGGLDAELADSTLSKGQQQLFSLARALLDHSQIVAMDEASSSLDPESEAHMMSVIRDKFRDVTVIAIAHRLDTITDFDKVVVLDSGRVVEVGVPRELLRQPSSVFRALYESSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V826</accession>
    <name>A0ABR1V826_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_014106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664112.1">
        <property type="nucleotide sequence ID" value="XM_066818420.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051480"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="35"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8067359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="182" mass="20463" checksum="9C216A8501DD06E4" modified="2025-10-08" version="1">MASKASPGRLLRLTLQVYRNQASSIEEREKFARDYLAKAAALHAKNGMEMYQQVYTPVGYRNGLDEMNRRSNRGWTIDDHDVTVEFYFRNFAEPNKVNTDPEFQDLQASEGPYVNLVHTVVTLGWVEKYVDGGDVVNIGEDGKSTYPPWSELNDLSTAFPARPAEGATYSLSEETKDGAEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V831</accession>
    <name>A0ABR1V831_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663224.1">
        <property type="nucleotide sequence ID" value="XM_066817532.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050592"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="461" mass="52414" checksum="4083DC00625DB87F" modified="2025-10-08" version="1">MDSLHPSDGTRHGNPSANGDQGSGTGILDLPLEILYLTFEDFRTEDLDTSTEDLRETCRALRLTCRRLSDVATSMLFSTLAIELDKKSVRRAEELVSCNPIIAASVRKVIISLACYNPEEAVDMSLFVEARLHDVDAYCRYYDPHWRLCRDAWDEVPRPTLRGSESLELKENCGNENYKDSPEVAECLRNGHRIFDAWDGDRYLEYYDRPCHFYGYEETEREKAVRTYRELLWKAHEVYHQKHQEQLELIQSGSFVQGIVRFLGFIRHEGLEFIITDEPMLDMQAGPYNPDCFRVVNDNKQLLTAMAVPHDWLEIFFSQSGDGDVSMPAVRLLSELPIACHRAGTPITNLTIEGFPTWGQFTLLSSEKPKGSEMETMTELGTAGEQLEKFEFGLEGTSFLAAGRRVQPHQKTGTMPFLTLEPCFQEVSSILFGSIWARLATTGRTALPTTDILPWALPFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V9D2</accession>
    <name>A0ABR1V9D2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663417.1">
        <property type="nucleotide sequence ID" value="XM_066817725.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050785"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="443" mass="49274" checksum="B6B51657D674F6DD" modified="2025-10-08" version="1">MYGNFFARKQAFHADSGIDRFPFGTRDVNEHAFASPPEGPAGVRGSRRIARARGRRVNHAQRRNHTRNTSGVSDDEPGDTSGNDTASGGEDDDEVMAEGETTTKISDDADSEFEGIYTRQYLADNNVKTAMEYYNLGRAKEWPDQMENSPIDFLDNLFNHHDNQNTICLKPTVMARVWYLFPNANEEDLKIIAKGVDRFFRYCTSTVDMEFRGRKKDIRNKCPKYSRNPLVLSVRASFRRALNSWIIGRDFEPDLPERGSVAACWLCHQRLEIDPFISGCAITLGIPGILTGGLGINRFGKPHPFGIAAGGTVEDLKKTAVTQDYLTTFGGQLHEHIDTKLEAFGPPVQDAHAVLQRITDLENQIKEFAGKNATLENRVTKYGEVPRSNAIIPNEYDDSSDDSPGPIARPGRLHRSGIASGNDMSIDLTQQEDSPSSDDEVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VB84</accession>
    <name>A0ABR1VB84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664047.1">
        <property type="nucleotide sequence ID" value="XM_066818355.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051415"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="138" mass="14752" checksum="33E642CE295A95C2" modified="2025-10-08" version="1">MAKRSSTSTKQSQTMGLPIALVLLSGAAYFTLTWDPTSASSAAGLLGILCHQAVLRPYEVDSRGWEMLLIYLAVNGGLVTGCVLTSTCGLLDAILLACRSGCVFLAGLYGSMLVYRAFFHRIGHFPGPFAARLSNLYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGJ2</accession>
    <name>A0ABR1VGJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010554</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664159.1">
        <property type="nucleotide sequence ID" value="XM_066814869.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047929"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="545" mass="60948" checksum="CA3A63DAD8C4A453" modified="2025-10-08" version="1">MSLEPICANRPCGKPGTASCGSCLMVLYCNQECQKAHWPNHKADCKASLLKSTWLPQWDTQRRIPAFMGDGVSMSVFNAEGKYPWGNMPAYDILNLPGNEGSNFQSDLDLLFAASGDLRNVFKTIVAVPSNYKANLQITINDRDIYIVARNVLMLLLLLVEKDPVVAAQNVVHLWYSAFITPSLMNTLKTEVEPLLRAVCTKIEHRSDSSLLGKTFGLPSGNLRVLLNKRSWNLLLDYTKVADVTVVNAQEKRRAVMLAPSRIDYRERAYYQEDPPTRFGAHKFRERGILLPLGASTDTFTVPNPTLFTGAGGWPLMDSSDPRNGWLMSQIRKSRTAAADNDVFGQLYYHIVDLVSDVHKRLWTTKVMVQMMRIAASDLIGHFGPSQTRFDRIETSNIADVTYLNPVGAVGLIGPLLKPPSVNPHATLITLFMNAIHEMKPARSNPSDLLNTVRQAAGYLSPSPARHMCDASYLRTMSLVHGEIELRSSDLLVGHGDEGEHTVVEKWPMLLKKRPGQDGAQEEFQDLSNTQHTGSDRYVEWRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VGX0</accession>
    <name>A0ABR1VGX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664263.1">
        <property type="nucleotide sequence ID" value="XM_066814973.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048033"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="50390" checksum="7FFE63D198DD1649" modified="2025-10-08" version="1">MAPNSDSEPHKRKRNDDDAGQGARPERIPQPPPPQLGNAAQISYISRTNVTRLKLIHGDGDTFSDVLTLISEYEGVLNRQESLASNLGAKLTGPRLLKAMEGVFEGTIITRPPQTAFTQDPVTWLDIVEFAKSNPSEFGLTLSPAGQRICQFRLKGVTVEISEDDWRLIVSGAMDRFRLVPAQPLEEDENVEFATLEILEQRLKMLYRKADEVARRARQLNYQLSGRKAAINARRSPQSSTPGFQAVNHIVRAAAAPAPGYDLNADLLQQYLAMAPGQSINPNHPHNHRVSLPPTPGTLATASSTPRISAPQPPPMSSNQPSPSYSSEPLNRDIHEEHRALVTAHIDKLGRGDPINPPCDRCRRLKMPCLKKQTACQGCTKKHARCMWEKITDDEVARLKGEHSNRIEESDEIGGIRDLHSPIIPLRHTTLLGLLPLTAAKRRLASNHHLQTALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHL1</accession>
    <name>A0ABR1VHL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_010924</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664529.1">
        <property type="nucleotide sequence ID" value="XM_066815239.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048299"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF13">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8070721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="546" mass="59989" checksum="7B04B31BC78CFED3" modified="2025-10-08" version="1">MARETQDNRITTAISRDDDTPGITTAATKVVTGSDVGAMVEEKELSTPSAGSATPPHHPIIIQEADYTQASAYAFKTWKKWRILIVVFLVQCSMNFNTSLYANGQKGMAHEFGITEQTARAGAGAFLVLYGFGCELWAPWSEELGRWPVLQVSLGLVNLCCLIAGLAPNFVTLLAFRCLGGLFSAGGSVTLGIVADMYRADDQQYAVLFVVLSSVGGSIFGPIIGGFVEYYMHWRWTIWFQLIAGVAVQLLHFFLVEETRVTCRLAAYAKMLRKQGGPLTNVYGPNEQKPWKEVLAPAEMTTLWFRPFKMLITEPIVAVLSLLSGFSDALIFMGFQSFGLVYEVWHFNSWQIGLTFVTIGLGYLVAYFSFFPAIKRQRNMELNNPNSDYAKFEARLWWLMYTAPCLPIGLIIFAWTGVPGSHWIGPIIGSAIIGIANFAIYQATIDYMVAAYGPYSASATGGNGFARDVLAGVLTWAAMPFYDHFRHTFPRHGLEFANTALAGISCVLVASAMAIYWKGAALRKRSSFAQKLAATEGHPEAVMVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHN3</accession>
    <name>A0ABR1VHN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_010930</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664535.1">
        <property type="nucleotide sequence ID" value="XM_066815245.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048305"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8070727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="480" mass="54480" checksum="170DC9A104218443" modified="2025-10-08" version="1">MTLLDALATQGSLTKPANMMGAVTISLILYVVSTIIYRLWFHPLAKVPGPKYMALWDVPSQWRSFITMDMVRHATVLHRQYGPLVRIGPDRLAIEGSVSWPEVYGVRSSRADNEYSKVPGLAFPNDHMALLGAGRDDHRRQRRQMGHAFSSSALHEQEAIITRYVDKFMDAITARARAGEALNLVDWLNFTTFDIIGDLAFADTFRSLDGDTTFVKNIFRGVVGGAYRRFWVQFPMLKNFRLGRVKGQARMAMGAEPKDGRRDFATYMLRKGKDGESVLSDAEVQALSSVLVIAGSETTATALSGFTFFIGTHAEKRRVLEEEIRNSFADEAEITMTSTGHLEYLNAVIEEMLRLYPRRRRSRHELVFQHATNRNPDSFADPDSFEPERWLGPNHARYNPRYAGDKREVVKPFSTGPRDCIGKNLAYAEMRVIICRLLYRFEIELLPGQERWMDDQKAAFVWVKGPLVVRLKPHVGAVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VI61</accession>
    <name>A0ABR1VI61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WDR59/RTC1-like RING zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011136</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664741.1">
        <property type="nucleotide sequence ID" value="XM_066815451.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048511"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049567">
        <property type="entry name" value="WDR59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049566">
        <property type="entry name" value="WDR59_RTC1-like_RING_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17120">
        <property type="entry name" value="zf-RING_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR59/RTC1-like RING zinc finger" evidence="4">
        <location>
            <begin position="503"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="206"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="574"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="646"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="664"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8070933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="679" mass="73402" checksum="630BFAFB6FD5B306" modified="2025-10-08" version="1">MSDLLPSKQELAQEYCIFGDGPEVCEHNADVALKYGRYDLVQVWRYAALLLRRDIPLELLEQTPRNSLVLVVAKNVINHVRDGKTIPGNPENQLAGKVKWGLHPLAKEFIADLFDYFEQAADVQMLAMLSCVFSEASTEDGVAYAESHMTQPETPLGMKAPSFSLDYFPTDASLWHTSSNYKSHVNSAVSTPGTVHTPVHIPGSYGSEEGYWLGDPGSNSYPSGGTPPPPKTTPRDSMSDADVTQSLSTSPDPRLFRRGNTALSTGFAASFPRPFTNAVSSSPPTKKRPSPGEAILANLTPNVTWGGSMILGPTSEPTSTARNSYSDDEQRKDEIQLSVINSISVEIEDQSIFDDDGWMTTPLLEPSRETAYSTYRYAYAEMLHMWNHPLARLEIMKFNVLKEDPPTSHFDSFGQESFRSAYHSPDSTSHITLVHQGTASPIVLAKKEQLQGVLSSGRGLDVVGYCRIHETQLDPIGPTYGVAAPGGAVGTCERCKRIQTRLFCVYCLAPLDAQYVPCLGCGCALHEACLAEWHSMGETECPAGDECNCAEEACNGQVERWAAMMGALRQGKLRKPSEDLDNNAATATAAGEGGRHRRANSIDKNDWESVASGSQLPAADGQGKPLLNVDSQPTLSAARISLGNRLRKSAGQWGSSASLRKKAGPGGSGGPGSSGLSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VII2</accession>
    <name>A0ABR1VII2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664847.1">
        <property type="nucleotide sequence ID" value="XM_066815557.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048617"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="292" mass="27474" checksum="0A873E54CA8C4070" modified="2025-10-08" version="1">MAGHTLRGTGGGDTRRGRARGAGHGGARGVVVGDGQAGAGDDGDAQSGRPVGRRRAVEVARREAGVDRGASAAAEVGEDALDGASVGAAAEVGEDALDGASVGAAAEVDEDALDGARGSNRVGGDRVGGSRVSGHSSGGDTGGGLRGGGSRVSGDSGGGLKGGGLRGGGSRVSSRSGGSSRVNRRSGGVSRVGSLRSGGSRSGGGSRVGGDRGGGSRVSSRNGSGSRVSSRSGGVSRVGSLRSGGSRSGGGSRVGGNRVGGDRVSGSWVSDHSGGGSRVSSRSGGGSRVGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJU5</accession>
    <name>A0ABR1VJU5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Suppressor of anucleate metulae protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665306.1">
        <property type="nucleotide sequence ID" value="XM_066816016.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049076"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="49750" checksum="703FF52C0398DE5E" modified="2025-10-08" version="1">MDTPQIVDGNPPHEAYAKAKPEVLNACIMCENPGHLACATCKSRYCSQACQKQDWKYRKMLRKSSVGPEYHLDSRPGPDYRRVIVFPHQQEAARLGLGPLPRRHGWTHFPRIRPAPPAPSNPFVNMSVSLNSGNKNPYLRFGRGLQYFSLGEMDQESIPRSSPYQEINQSALSLTKPGHATPASVHSSSRPSRATRLVAPSSDMASSGEDTTLKDFRLFVDSIITDKANPCIIDPDRYALKLTPNVNSEVWPALKLNCRADMERFGLQREEAIEPVLVSSIPLTGKRHNVGLVESMGLSWAWQEATISNSSIRGSRELLRTDQDFGFFFKGVELPEDITLFNFQEVVQNAFDSMRHKDVQYTGTIMLVHKKGRAIQRAHLQAVMQYKDLVWAEGIEGLDSGRLPRTPSPNFMSSRLTREKFEAFWNNVWGSFGVPSPYTLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTA9</accession>
    <name>A0ABR1VTA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RAVE subunit 2/Rogdi</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665337.1">
        <property type="nucleotide sequence ID" value="XM_066813375.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046435"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028241">
        <property type="entry name" value="RAVE2/Rogdi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618">
        <property type="entry name" value="LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618:SF1">
        <property type="entry name" value="PROTEIN ROGDI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10259">
        <property type="entry name" value="Rogdi_lz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="38800" checksum="91350746F36E31ED" modified="2025-10-08" version="1">MSIEIWPPIAPDQLKVEEDATQTLKTLKSSLEETYALLAPIDPGATLVVSTPKHETVKGYVTRVGTRLVKGSIALRLRTQPPVVLSLNPEKPIHVPELTTLNTLLTQSVDILSFVVSESFSKKGDAEYHADPRFVSSQLRLLAEYLSEANIIQPPSQRPLSSASHSSSISSAGGPNAIIPQPPDTTWTHSSVPPTCFSPPLDPAHHNLSVYLTIQDASLVLYVRALESADAPVNFGTKLALAIGTARRLEHDEADRIFGYCPEGADDPIAAAGSTMQHPPNPLVRTRSSTANNGARGGGMGKGRGTETQVYVREKVRVVSTDPSLLSLSSKLGALGNALALARRNLAVVMGELDDGGGGGGAEEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTF5</accession>
    <name>A0ABR1VTF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665490.1">
        <property type="nucleotide sequence ID" value="XM_066813528.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046588"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="405" mass="46255" checksum="DDC49F7A3CFE832E" modified="2025-10-08" version="1">MENGLFTANTSAAGSSQPFHAKDDSGNSMAPDKPSSSGTGFSFNDFYLQRAEQLGWDTQRDRIIQEYNASQPAQQWADETSEDFRRIRQSLLEDGVPTKMLTSSFWCITHCQQAKDRVRESWIKQGIWKDSWGQTGPRRADSPSEPAWKHEEPIEVEPESDSETEEDPLTTTLFGAFGRLRKSREGRRWRAERRATRNRERDASRPYYRFMYQLGEERFAFQGRSFLNDSEVINSVDYNTKAYETVKARWVKRGIWDQRWGILPGMKWKHEQDLEGFLIELGPRPVTEYRRSGRKTVRTGNGSPQVADSYHDPEPSVVRSVEAEGPLVNTGTTRMHDPDADNPSESAQGAPSAIARARQSAGAQIMRRRLRRRSVGKRRRLARPAGVSKSQPKSAIKLEYEESSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTJ1</accession>
    <name>A0ABR1VTJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_009221</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665498.1">
        <property type="nucleotide sequence ID" value="XM_066813536.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046596"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024491">
        <property type="entry name" value="Se_SelK/SelG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10961">
        <property type="entry name" value="SelK_SelG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="7"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8074558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="211" mass="22111" checksum="CFCE0F05F43B70B8" modified="2025-10-08" version="1">MSATVNISSQAEWQRILGSSTIVVADFYADWCGPCKMVAPTFESLSTKFSKPGKITFCKVNVDNQQPIASAHGRRRHRDHPGRQPPALTAGVEKAVKLAGAGGAQGAVFKTPGRTLGGPGAAGSRGGQRLSRPWSFSSFGLFNAILTFFGLYFVSLFSFDPYKAAENSDFNVHKPSNAVFGRGTGGKKVGGQGDAARPSGGVRTLADLGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTK9</accession>
    <name>A0ABR1VTK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009256</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665533.1">
        <property type="nucleotide sequence ID" value="XM_066813571.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046631"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045438100" evidence="4">
        <location>
            <begin position="19"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="158" mass="17574" checksum="04A509F06615A561" modified="2025-10-08" version="1">MKFSTVNVLAFAVPALSAAIGNVSLAVDTLDKRFDTVALFPKMVHCPATLGEPEARSFDQHQMEATAGWFAENTRRMDFTTECKDAYMWEVPMLANGNPWTPGIENGEPGGYRLYFTAGGGKAEWCGSAVHYYPKQEKSKDPEVRRKNSVFSRCVPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTM5</accession>
    <name>A0ABR1VTM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665550.1">
        <property type="nucleotide sequence ID" value="XM_066813588.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046648"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15511" checksum="802329C27778EE36" modified="2025-10-08" version="1">MAGEPVDQFRERIKREQRSRSSGTAAGSGSEAGNKGQDNGADKGEDEGNDITKIRLRENSRFQRETAWVFKRTETMWAHLQNYANSIHANFDNLRFVTHDGSRINRTDTPEWLGLEEDEIIDVLPMAIGGQRCLEAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUQ8</accession>
    <name>A0ABR1VUQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_009647</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Interacts with G-actin; ADP-actin form.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665924.1">
        <property type="nucleotide sequence ID" value="XM_066813962.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047022"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11284">
        <property type="entry name" value="ADF_Twf-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11285">
        <property type="entry name" value="ADF_Twf-N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028458">
        <property type="entry name" value="Twinfilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759:SF1">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ADF-H" evidence="8">
        <location>
            <begin position="3"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="ADF-H" evidence="8">
        <location>
            <begin position="174"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8074984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="333" mass="36602" checksum="8EEEA3A558474C80" modified="2025-10-08" version="1">MQSGISASQELVSEFNKLLADDSLFGLLVTITNESLTPVTTLPTTSAAADFAQNLAQLEPHLQPAEALYVLLKRHPDAPRLIAVSYVPDAAKVRQKMLFASTRLTLVRELGSEHFRETIFATTAEELGAQGFAKHDRHAELEAPLTEEERTLGEVKRAEAEAGAGTGQREIHLSKNMNMPVATDALVALSEMGHGPSRGLVMLKINPQSEVVELVPHSGTASSIPELVSTISSTEPRFTFWRYTHTHQGTESSPILFFYTCPAAAGKSIKFRMMYPLMKRAVLAVAEGEAGLQIEKKFEVEEPDEITEETIMSDLHPQVEVKTAFKRPKRPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VW14</accession>
    <name>A0ABR1VW14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Polyketide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_010050</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666327.1">
        <property type="nucleotide sequence ID" value="XM_066814365.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047425"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="7">
        <location>
            <begin position="378"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="8">
        <location>
            <begin position="1283"/>
            <end position="1581"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1633"/>
            <end position="1710"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1745"/>
            <end position="1822"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="4">
        <location>
            <begin position="1283"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="4">
        <location>
            <begin position="1432"/>
            <end position="1581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1612"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1707"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1621"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1708"/>
            <end position="1726"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="4">
        <location>
            <position position="1316"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="4">
        <location>
            <position position="1494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8075387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2100" mass="228059" checksum="F490A77C2B4FD919" modified="2025-10-08" version="1">MQSATVLLFGDQLASKTSAVNRLYEIAKTRPSLRAFLRDATDVVQCLRQDLHPCERQLYGDFADIRDLTYRHESAEHLNEAVGTTLITIIQLGELLLLTEDEPTIIQLGELLLLTEDEPTILNADSQTYGIGVCIGLLAAAVAATATTARDVTRLGLECVAISFRLGIELWRRTRSVEDSPESWACTFVGIDAAQVQERLDLFNQDCHRLRAAYIGVQASTWATVFAPPATLKRLMESEHFSQVSTSRLASAIAVHAAHLPILDVDRILGTSPLLDTPARCEGVFSSNTCEPFTASTLRDLLSLIVADIAQHPLYLEETIKNVASSLQGNTNARLLTVGPTHSVSFVQRELQRIVPTVTVSQINIDDENSSEEYRRGSDRVAIVGMSGRFPGSDSISELWELLLSGRSAHQRIPESRFPIDDFLDPSCEAPMAVSTTFGCFLKNPGEFDNLLFSISPREAVQMDPVQRLLLMTTYEALQMAGYSPDATASTLRAHMATFLGQSAEEWKAINDQEGIDTHYIPGTMRSFAPGRLSHYFRWGGGITSIDTACSASATAVHLACNALLSREVDCAIAGGGHVCVAPELYSGLSKGGFLSKTGPCKTFSDDADGYCRGEAVGVVVLKRLEDAVREKDNILAVLRDTARNTNAGATGSITFPSSTAQADLYRTILQSNGVGPNEISYVECHGTGTQAGDAAELSAIIDTFSASRPSDFPLHIGALKAAIGHAEGAAGVSSLIKAILIMQKRIIPPQPNWPFKINHKFPDLDEAHIKVADGTAPLRPSRDGNGLAKIIVNSFDAAGGNVSMLIEEAPEVSEWRAEDQRPHHVVACSGRTRASLEANEARLKEYLLQHLDTDLASLAYTTTARRMHELHRSAHVVESVQDLLSKFGTGYKAPLKDAQLMFSFTGQGSVYTGMGAELYHTMPSFRATLDSFQDLCDAQDLDRFLDLIIGAQDVATATACQTQLALVSLEIAMAQLLGSLGLQPTLVMGHSLGEYAALCVAGVLSVSDMLYLVHTRATLIQEHCTAHTYSMLAVNMAHDDAVDLLREFKCPTCQIACINAPGMTVISGTNEELATLQSTLQARGVKSSLLKVPYGFHSSQLEPVLEQFEEAARKVHFNAPRIPVASTLLGEVVRDDGIFNAAYLRRQMREPVNFLGAVHACEEQRLLQVNTVALELGPHPVCTALLAKSCSTKDLTTLSSLQQGQDGWRSFSNYLAALHTAGLPINWREFHRDSEPCLRLLDLPAYAFDAKTYWVPYKTRRAIQIPAEVTAPAHQSLPYSFLQRLDSLTSEDGKTEARFTSSSTHPELTVAIQGHIVGGVVLCPASVFVEMAHTAVFYILKSTGLADEGFHLEVADLQMTHALVVHARDEEHLIHIDCSLEDTDTEVAVTFFFHRPDWRLGQPRPVQQWGFMENLVRRRVTNLLETAKGGPTHRISRDLFYKLFEAEVDYGKPYQCIEEAYLPPDFQDAVAACVLDDSTGSQGQFTCNPFTMDGIVHLSGFLLNADPAKPKDVIHISNRIGSFQLLAPIANRTHCMCYATVREQSAKGLTVCDVYVFDQDGLIALCTGITFQRMTKEIFSIVIGGHANAGSPAAAPAPKIIAAPLSNRGRRLRDFPDPPSSSQGAAVRTSQPDVPNHADTLLSIVAKRTGVSLDELEPTTDFTDIGVDSQMSIAITSDLQKQTGVQLPAAFFLTYTTVAEARKQLGATEPAKAKPTPSKAAAESPVTKQSSSGPRDVRRGTSSSSTERRSEILLQIVASALGMAPGDFADVGDFEAAGVDSMLSIKVMSQYKQKTGQELPASFFLNHPTVADVEAELDGDVRGADTDITVSSSNPDSKLRPVFMIADGHGSADAFVHLAPLENNQRLYALESPFIDDPDAFDMSIPDLAKVFIRTIRRLQPRGPYLIGGRSAGAAYAYEVAYQLAVVEREPLSGLLLIDMRVPRAIPQARHIDTAFVARAWKVIVEHTKVLLDPGDLAHAAATIKALHSYTPRPFPASCPQLRPRRVAVVWARWGVNENPDQTLRDAGVQRAAAMGPTLGEAADPAGVSLADFEAEFKSWFWGARSTFEANGWDALLGGGGAGAHGGWRSLLYDEAATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWD0</accession>
    <name>A0ABR1VWD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666447.1">
        <property type="nucleotide sequence ID" value="XM_066814485.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047545"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471:SF1">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="300"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="545" mass="61849" checksum="35E4465BFCC28BD9" modified="2025-10-08" version="1">MLGTSLRELLFIRLCIVLLQYGTLILLAGLAAAAALGGWDALAHPVSKVALGYVVLDALYYFFLWIPYNRRLWDEADHPPPLSPEDRRALFLRCDENVPDFDRYLRLWFLGADPAEIRRDNVRDFILWAFFDRRPGAESADEAAECAGYLDIIEQRLGHELEPGRGSAQSLRLTFDSIETRYRSFIWYILIWIVDLGTHVQLAWHGFEYHALPAAKFASVLPPRMQSFFARNRSASGELSYWHRPHTAKGKKPIVFLHGIGVGLWTYASFLSSLGKHVDSQGEAGDDEGEVGIIALEIMPISFRLTAAPLGKLDFLDEMARVLAAHGWGEFVLVTHSYGSALATHMLHSRELGPRVDSVVLVDPVTILLHMPDVAYNFTRRRPRGANEWQLWYFASTDPGTAHTLGRHFHWKQNIIWKEELVAKDNDRAFEMNGNDGAAHRGGEGRKRRQRNVAVCLVGRDLIVDTLSVARYLAKNEDWLPGLGDPDRAEADNTLDDMHKKAGYDHLEKDGIELLWFDGLDHAQVFDDQKHYDKVKAVIHRYCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWM6</accession>
    <name>A0ABR1VWM6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-hydantoinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HyuE racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666601.1">
        <property type="nucleotide sequence ID" value="XM_066814639.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047699"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052186">
        <property type="entry name" value="Hydantoin_racemase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053714">
        <property type="entry name" value="Iso_Racemase_Enz_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047:SF6">
        <property type="entry name" value="CN HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="264" mass="27607" checksum="0B0C4AA52F3A91AA" modified="2025-10-08" version="1">MDSPLPSVTGHNAAPISILLINPNSSPHMTDNCLKSIAGKIPAGVTVHGFTAPRPAPSAIEGRADGVLSAAECLRAIVPIQDRFDAFLVCCFSHHPLVDALREEVPHQPVLGIMESALYASRMCGSRLGVVTTSERSAVNHELAIAGYGFAPYSAGCAASRISVLGLESQPKEVVYAGVVGAAKELVEQRGADAVCLGCAGMTGVREACEEALGTAERQVMVVDGVAVGVQFLTALVREGLGTAKRGAYRPAKAGRDARKQEWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWN7</accession>
    <name>A0ABR1VWN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Haloalkanoic acid dehalogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666552.1">
        <property type="nucleotide sequence ID" value="XM_066814590.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047650"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF9">
        <property type="entry name" value="ACID DEHALOGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="26996" checksum="EEE6CCFDF0AEBB93" modified="2025-10-08" version="1">MATTLKLSDYRLLCFDVYGTLVDWETGILTALKPLLAANDASTKFSNEHLLTVYHELEAAQQAETPSMQYSQLLATVHPKLAARLGLSSHAPTDAESQAFGNSVGAWPAFPDTVDALRRLQKHYKLVVLSNVDRESFAATNAGPLQGVPFDLIVTAQDVGTYKPDLGNFEHMLRRVEAEFGVKPEQVIQTAQSQFHDHHPAKKVGLKSSWIVRPGAIMGNRGEELYDWKFDTLGEMADVLESEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VXJ9</accession>
    <name>A0ABR1VXJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666006.1">
        <property type="nucleotide sequence ID" value="XM_066814044.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047104"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="191" mass="21858" checksum="958B0816C2E6D58E" modified="2025-10-08" version="1">MEIDTQSKPEPDCHRKDDQQQQSQLHKQQQQQQKPAPHSDDGDDDQQGQSTWVAYLETERNRRFDPVDGSFMSIFRDLLRSNAVNAAHDAAAAIDRAFADGWLPQRSMLKHGGDEGLADFVHLVYNLIFELAPLLAHDSAQHVRLFELLVELRKLPPRSFELNSVQKTFFFSTRVYFTLSIAFLAFTSGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZM8</accession>
    <name>A0ABR1VZM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Quinic acid utilization activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_010283</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666560.1">
        <property type="nucleotide sequence ID" value="XM_066814598.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047658"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052783">
        <property type="entry name" value="Metabolic/Drug-Res_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655:SF2">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="771" mass="84529" checksum="BB5BD5CE170AC6FC" modified="2025-10-08" version="1">MPPAAINATTMGKKRQSSEADQDKPMPNSKSSPAPKRQRVSRACDQCRSAREKCDGIQPLCFPCASQNRSCTWEEPKKKRGVQTGYIRTLELALGWIFDKIPGTEEALHAMLTHEGGQGRSLLVGKDSGSGSRLHRKWRKSNVHKEIERVLAGGDASDVKGEKPSSANGDSDSGDDADMPYQPAVDQLHPVVGANAVSVARPSLTPDRAKTAVTQLPPNCWRLMDIYVSYTHCWFPVLDKVSMQKTSYLYKDEGLELSPDEPDSAAHAELWAALALASYQEQASQRKSEDSKPLAQSVDPMAFYRVARSLIPSEDGHFEVRHVTALLVLSLVNIGLQKLDPAWILIGLASRLTSQLQNQPGIRSECAWRLHRAYMGCFILDTVLSIRLGRTPHLRTEESSGSITGSLSLEENDREEWDGWIPCFGFGPQPTPHITSRNPSHSLSTFSSLYEIHRVISSNLYSPLGSNPRPNEPFSLQVQRAIALQQNPRSSFANYITNGGKPSVLLPSLSVLRLAYLGLESQQYPSTPPSPIPVLQCLDDHFRNFGACSVTPLFSTYMSLVSQNHGLGQWNPVDRSRWTDSIAAVESVWGSSVTLPLLQTSQPRLQVESFTAPSHRIPPGTSDLGNTQLPTPASYYAEKLPNLSQAMLGEMYAHPGSSNTVTNITAAPSQRQQPLSLNNQLHSPTNSSVFGNAVTMDSMAVAGMPSTPQFPMHGRPSFSSGTFDYDAILDDIASLDRTDRMESDPQFMTNLGFAPGSSLADVFTQDFMGYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W020</accession>
    <name>A0ABR1W020_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphorylcholine phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666393.1">
        <property type="nucleotide sequence ID" value="XM_066814431.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047491"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046931983" description="Phosphorylcholine phosphatase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="362" mass="40198" checksum="F6171230445C8D1C" modified="2025-10-08" version="1">MKCSIHTAVAALGLATAVAASPLASNGSVLPELRNWPRAAAQSLTTMIKRNANSSNYAVFDMDNTSYRWDLEESMIPFLENKGVLTRDTLDPSLKLIPFKDTPQYNETLYSYYLRLCAINDFVCYPWAAQVFAGLTLRELKGHVDALMALNGSAVPTTYWDGDAIVASNVSAPQVFRRQTELYHALTRHDIEVYVVTAANEELVRMVASDPRYGYHVKPENVIGVTTMLRDPADPNTLTNSRMKISAGTYNATANLDKLVVGPYLWSPETWYAGKYSAILMYIDEWKKPVLVGGDSPGSDTYMLFHGVDAAKGGVHLWVNRSKSKYQQLQTMIAEAAEGQKKNGLEVTVDKNWVVVKPEEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7C9</accession>
    <name>A0ABR1W7C9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666865.1">
        <property type="nucleotide sequence ID" value="XM_066811523.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044583"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF3">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="1">
        <location>
            <begin position="39"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="286" mass="32388" checksum="A05AAB5928F081DA" modified="2025-10-08" version="1">MEMARPNNKRTLLWDWTLTRDHDTTPTLQATTASLAKSLSSHRIASITNWNTWRPPELNPADLPFRPMIRTPAQLEGGEWDMIRGSIDAEIQSGGGTGSVIVHTFNEPERIPLSIDDALRLWRTRILPLRQSHGSQRVKLVSPACASDAQGSWWLDAFMDSLSLDSERDERPDILGLHFYTMPDQTAEQGLAAAKTYFAERRARFDVPVIVSELACTSRDSAVVNRFTRDLARWLEEPEQDWVVEYGFFGVMREVADGFVSPATQMVDQEGAWTGLGRWWVGLEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7P3</accession>
    <name>A0ABR1W7P3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666977.1">
        <property type="nucleotide sequence ID" value="XM_066811635.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044695"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="330" mass="36222" checksum="702F1925A1E7CBFA" modified="2025-10-08" version="1">MSSFQFKPNARPFVPFRTLSEMALGLSAKHASEGAATPSVNSSSNTSIYDDEWGFSSNKVECQAIFQYHTCQCRTRTPVWVCPKNQSNCSHPNPSILVSGLPHACRVDTKVGGRALILQQKQQQEQQQSRSKKGKKNNIQNQQTGPRTEACTAQDPANVGWRGDTDAALHTQVLTLENFPGLTAEDFDEIVPVFVADGKSWREEVWERHEQRRVAAYASSEESSEPGRNSDSSSSEDEDEDCATGTASAGDDAMEKFNRLLYGAVGSKTPAAAAVSVVPECESEVDDDGDAEYDCDDEDEEEAAEERRPSLRSLVEDSVADDKDKKKSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8M5</accession>
    <name>A0ABR1W8M5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_007585</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667242.1">
        <property type="nucleotide sequence ID" value="XM_066811900.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044960"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05684">
        <property type="entry name" value="S1_DHX8_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049621">
        <property type="entry name" value="S1_DHX8_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="196"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="491"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="652"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="127"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8079767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1117" mass="124946" checksum="54CEF9BC3FE05218" modified="2025-10-08" version="1">MDDFEELELLGLVSKVTSELKNYLGISETTLSEFIIAQRLESKDRHDFQKKLAGMGGAKWPNSLFDSIDRLVCTMHPKMKKSATNGSEDHHRTLEEKKSLFSGLAIPDKPVPNDEADAIDDTLALLEDLAPKPKTRAPERERERSSRKRTRSPDDRDRRRRRSRDRRDNKSRRHDYDDDGFKRPPVPEVDNEPILHKVYEGHVTGLKEFGAFVNLHGVRGKVDGLVHVSQLVEGQKVNHPEDLLTKGQDVKVKVTKIEGNRIGLSMKEVDQVSGQDLVPQSRIRSGANFEAVGAGSGANSMALGGGRNGGGFADTNADALAEYASQPRRQKKRMTSPERWEIRQLIASGVAKASDYPDLEEDYHATLRGEGDMELEQDIDIEVRDEEPPFLVGQTKQSLELSPIRVVKAPDGSLNRAAMSGTNLAKERKELRRNEAEAAEADSKNMIAPKTEAEPEWKRVAKSEPLGKRTNMTIKQQRESLPVYAFRSQLIKAVHENQFLIVVGETGSGKTTQLTQYLAEAGFANNGMIGCTQPRRVAAMSVAKRVAEEVGCQLGDEVGYTIRFEDVTGPSTRIKYMTDGMLQREILVDPDLKRYSVIMLDEAHERTIATDVLFGLLKKTIKNRPDLKVIATSATLDADRFSSYFFECPIFTIPGHPLDGAPGDILVFLTGQEEIDTACEILHERMKALPNVPHLHILPVYSALPNEQQSRIFDPAPPGERKVVIATNIAETSITIDHIYYVIDPGFVKQNAYDPKLGMDALIVTPISQAQANQRAGRAGRTGPGKCFRLYTEQAFSTEMSPVTIPEIQRQNLSSTILMLKAMGINDLLNFDFMDPPPTNTMLTALEELYALGCLDNEGLLTRLGRRMADLPMEPSLAKVLVASVDLGCTEEVLSIIAMLSIPSIFYRPKEKQQVADQKKAKFHDPSGDHLTLLNVYNGWKREGFSNPWCYDNFIQARSMTRAKKVRDQIVDIMKRHRHAIVSCGRDTSKVRRAFCAGFFRNSARKDPQEGYKTLIEGTPVYLHPSSALFGKQAEWVIYHTLVLTTKEYMQTTTTIESKWLVDAAPTFFKVAPTDRLSKRKQAERIQPLYNKYAAEDDWRLSAQRRGGRSGGGGTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8V3</accession>
    <name>A0ABR1W8V3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleolar GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007736</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667393.1">
        <property type="nucleotide sequence ID" value="XM_066812051.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045111"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024926">
        <property type="entry name" value="NOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038919">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="8">
        <location>
            <begin position="175"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="557"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="558"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="601"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR038919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8079918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="661" mass="75035" checksum="8847D864C6C84988" modified="2025-10-08" version="1">MKTTWKDSASMLTFFASPRKIAPVPTSQEFLDIVLSRTQRRLPTQIRSGFKISRIRGFYTRKVKFTSETCAEKFDAILSGFPRLADIHPFHADLRDHLKISLGQISTAKHLVETISRDYVRLIKYAQSLYQCKQLKRAALGRMATLIKRLKDPLLYLDQVREHLGRLPSIDPTTRTLLICGYPNVGKSSFLKSVTRADVEVEPYAFTTKSLFVGHFDYKYLRFQAIDTPGLLDSPLESKGPIELQSITAIAHLRSALLYFFDLSEQCGYTVHAQIELFKSLKPLFANKLVFLVVNKIDVMRPEDLDAETAKEFQSLLNDADVEMLQLSCNTQEGVQEVKNAACERLIADRAAAKVKAGTNNSGDVGGRLADVMKRIHVAIPEGGLRETFIPEAVKNMKKYDKTDPERRRLARDVEEENGGAGVYNVDLRADYLLENDEWKQDRIPEIFDGKNVYDHVDPDIEAKLQALEEEEERLEAEGFYESEEEIDDEEEAQIRTKAELIREKQALIRNEARMRKSLKNRAVIPRKLVKQPLSELEEGLDVLGVDTTDLGLRARAQANTRGRSVTRSRMGTEDGDAMDVDSTPRDRLRSKSRARSPATNRREDGVVDATARDKAERQMKLGQRKMNRMAKQGEADRHVGTTMPKHLFAGKRSMGKTSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W920</accession>
    <name>A0ABR1W920_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dynein heavy chain, cytoplasmic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Dynein heavy chain, cytosolic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PG997_007784</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Consists of at least two heavy chains and a number of intermediate and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667441.1">
        <property type="nucleotide sequence ID" value="XM_066812099.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045159"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="1929"/>
            <end position="2067"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="2586"/>
            <end position="2741"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="2928"/>
            <end position="3094"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="1629"/>
            <end position="1659"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="3172"/>
            <end position="3248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="3412"/>
            <end position="3453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK8079966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="4339" mass="491035" checksum="346216F7621C46F0" modified="2025-10-08" version="1">[encoded data, 4339 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9G9</accession>
    <name>A0ABR1W9G9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Calcium-binding protein NCS-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007958</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667615.1">
        <property type="nucleotide sequence ID" value="XM_066812273.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045333"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="190" mass="22030" checksum="9D0A4C3BD9F5CC2F" modified="2025-10-08" version="1">MGKSQSKLSQEQLAELQKSTHFDKKELQQWYKGFLKDCPSGMLTKEEFQKIYRQFFPFGDPSSFADYVFNVFDSDKSGSIDFKEFICALSVTSRGKMEDKLDWAFQLYDIDGDGKISYDEMLKIVEAIYKMVGSMVKLPEDEDTPEKRVRKIFRMMDKDENGSLDMEEFKEGSKRDETIVSALSLYDGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9R7</accession>
    <name>A0ABR1W9R7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Terpenoid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667696.1">
        <property type="nucleotide sequence ID" value="XM_066812354.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045414"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="371" mass="41689" checksum="7E54438B727403CD" modified="2025-10-08" version="1">MEFKYSEIVDPSRYETEGLSGGIDVRKSRLTELEDRGAIRAHQDWARHVGPCKGYRGGLGPEYSFISVVMPECIPGRMEVVAYANEFAFMYDDIVECMGCDLGQTENNEIMNGFLEASQLRSGSKPNAVDERAGKKQIQSLIFSEMLSIDPDCAKTTMKAWAQFIESGSARKHDVRFKSMAEYIPYRIKDVGEMYWYGVVTFGMALHIPDHELERCQALVAPAWIAVGLQNDLWSWPKEVEAAKAQGKDHVINSIWVLMQEHSISVREAMQICRQLIKGYVAEYLATVEAYRDDEALSGDLRRYLVAIKYSISGHLVWSLNCPRYNPEVSFNKRQRSWMCNGVPATGPSPNLTLQQGGETGYIGGKVALPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCE0</accession>
    <name>A0ABR1WCE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome b2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008480</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668137.1">
        <property type="nucleotide sequence ID" value="XM_066812795.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045855"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02922">
        <property type="entry name" value="FCB2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037458">
        <property type="entry name" value="L-MDH/L-LDH_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF148">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE (CYTOCHROME)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="8">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="9">
        <location>
            <begin position="103"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="483" mass="53659" checksum="712716D4C38DA664" modified="2025-10-08" version="1">MPLSGVEVAKHNDKNSCWIVVHGKAYDVTEFLPEHPGGPKIILKYAGKDATEEFDPIHPPDTLDKYLDKSKHLGPVDMSTVETAEKEFDPEEEARQQRIADKPALAQCYNLLDFEAVAKRTMKKGAWGYYSSAADDEITLRENHEAFHRIWFRPRVLVDVKEVDTSTTMLGTKVDIPFYVTATALGKLGHPEGEVVLTRAARKHNVVQMIPTLASCSFDEIMDAAEGDQVQWMQLYVNSDRAITERIVKHAEKRGCKGLFITVDAPQLGRREKDMRSKFTDQGSNVQSGQETDNSQGAARAISSFIDPSLSWKDIPWFKSITKMPIILKGVQRVEDVLKAVTMGVDGVVLSNHGGRQLDFARSGIEVLAETMPVLRQLGLENKIEVYIDGGVRRATDIIKALCLGAKGAYGLEGVDRAMQLLKDEMEMNMRLIGCSSIDQLGPSLIDTANIGSHVTSVPRDSLGHRVYDQLASPEWKKPKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCL9</accession>
    <name>A0ABR1WCL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008995</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668652.1">
        <property type="nucleotide sequence ID" value="XM_066813310.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046370"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055496">
        <property type="entry name" value="DUF7068"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844:SF1">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23238">
        <property type="entry name" value="DUF7068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="4">
        <location>
            <begin position="49"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="499"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7068" evidence="3">
        <location>
            <begin position="654"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8081177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1325" mass="146485" checksum="FE4336361946C9AE" modified="2025-10-08" version="1">MATAECLPRPRTTKELLGRLRDIGSHSGNDAEDRRPQNQEEQDSTSDGLPSARCKKEAEALSALSRRMTQIFIENPKDLYANVTEAAALAPFVRLEEFPGFFNAFVQAIASGSGDHAVPNINVLEGFNAVLHCPQALQCTQHEDLRTQLSLGHAVLGLKNRLTTAGLAADLETQYRLLRTLCAILDAMNEVKFGGISEYDVVEPLIKELQKSSGHSELRIAQAARYASESLRGIPSDVSPWKKLGESMIKTLGVAANVSGSVATLDPAKLLEGLLDAPGAAEGLVKGAIDNPEFTLSKDKDFLCGLCSQLEQAAHEGGQDSPVVLVLKDFLLLKGGMSSSRRVQAWMQLTVPTAGLPKPSLGHRLNSKFGGLFGASTFGTSVGYSKVAVGRLGDASRLLRAAWETCPEANLFYADQVVRDFYTNKDLGLLNVERLDPTKCLPMAQCYINMAIVEGSAGSAPPLGSLRRRLDVWEVDKEHSVTLPSLFQPKDSKAPAPKRVLIRGKAGVGKCTLCKRVVYDSIHHDLWADIVDRVIWLPLRELKGRDKWDYDLRQLLRERFYRGVEDGELLASALHGETTGEQSRTLFVLDGLDEMQGETSNLLRILLGQPRVIVTSRPQGVNRNLIGNIHREVETLGFYHDQVKQYTATVSPEQSERIQVFLDTHPAIEGLMRIPVQLDAFCYSFETDAFAIDRTPQTMTELYRAIEQVIWKKDVVQLETKPPPQLEPDVPVRGPPFHPVRDQGARAGQDERVAGARLCRDGQQHGGIRHQVHGQLLGRRERRVDQMPPAQAEMPKFGELDRLSFLRTSGQSSSASSNYHFLHLTYQEYFAAQYFVHHWPHKQLPGIGMTAEAFLRREKYNPRYDIVWRFVAGLLQMKGTAASFFETIQEGPCDLLGQAHQRLVMRCLAEIHHDSDLGGLRASLEHCLRQWFLHANPDGCNSSMAKEMEFPEKVLLDCLPGASEALRRILVEILKDRPRMLPQTVECCAAPFKMEGGEDSPLSKLEALEILVAHYIPNNLVPEVASLGSRVRKLPTLPPGIVRKLVEVLKDPDYHTWEAAAWVLQRTPVRLEILPELLAVLRHPGLSDERVVGEVLWQAEILPRSFLRGVLDVLKGPQSTNRDAAAQVLSIQGLELPSDILQEIGALLDDPEPEKRGAAMKSLTRQPSLPAEILRKVLNQWQKDGPNFAEDILQRQTVLPEDILGSLVDLLKAEPDVRRAAACVLSEQSSLPDNIVDRITTLLLDDAHQDGEIASCAAFALPRPTPLTSGVLHKTIALGLGGDRGRYRAAVYAVGVQPTLPADILPGILALLESTSENVWQETGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WD08</accession>
    <name>A0ABR1WD08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_007862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667519.1">
        <property type="nucleotide sequence ID" value="XM_066812177.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045237"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8080044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="175" mass="17665" checksum="9F0A0B0C3D6B29F4" modified="2025-10-08" version="1">MSAAFSATAYTVACKCVPGIIGMTEASTTANRRVPCTSRSAPTHPPSAAGIMAQVPLGCALDGRTSPRDTSASHIASSVCAAAPGATSHGTVPGQEGRGAVQVAYPADRGQDHGAVGRVGEGLVLHNGGGLCWAQSNTIEGGRPLVPNPAAVKGNSMAAASRPPKCRRRIARWAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WDT1</accession>
    <name>A0ABR1WDT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8081172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668647.1">
        <property type="nucleotide sequence ID" value="XM_066813305.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046365"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="22"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8081172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="449" mass="50708" checksum="8B8DBF0082591313" modified="2025-10-08" version="1" fragment="single">MRLLNTSTLTLKFFPGKEKPTYAILSHTWGDDEVPFQDVGSDGPAWAFEGPGRDRQKGVLRSAGQAKSNGYDWIWIDTCCIDKSSSAELSEAINSMFRWYEESDICYAYLSDVHGSDLGGSRWFRRGWTLQELVAPSDVELFDASWKFLGRRNAMASHIAEISGIDEFILRHGHHRHCACARQVRMPTFANQTSTPCDCEHNRHNTYSSRTIFPRSSIATRMSWAARRETTREEDIAYCLLGLFDVSMPLIYGEGQKAFSRLLKEIAQTSNDQSILSWHADYDFPDMRFYYPISPACFPFSFIHHNAGDMEAAASAFVTPLGLEVTMLLCPFNPAEGEHFGGRGDYELRRCFGILDCTISCDVLARPAIFLERVGDQQNLEYERIDVDRFYAVQAGEQGDQVVYTDRLRGRDLIGTSPSGSKQTVSILSSIDMHKANIDLTAAKRRTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEG2</accession>
    <name>A0ABR1WEG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell morphogenesis N-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667968.1">
        <property type="nucleotide sequence ID" value="XM_066812626.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045686"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="197" mass="21992" checksum="3F47F39194D98599" modified="2025-10-08" version="1">MPLLTSSSVFVAPSQALAELSQDPLRHSPRSTSRLNVLDEDDSWENTVRPLPLSLEPPASRSASHSRESSFDKSQSIGLAGIPESPPPLEGDSIWAPPADFHRSWVPTLEEWEFGQHVLESIEPTDDCCRRRWVIERKNGTAWDDSNGGGCDHGFPTANSLVRLNRELQHASHVREDPIHDRKQFGDTYAEEGRAHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WEX6</accession>
    <name>A0ABR1WEX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Profilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_008461</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the profilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668118.1">
        <property type="nucleotide sequence ID" value="XM_066812776.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045836"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00148">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048278">
        <property type="entry name" value="PFN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005455">
        <property type="entry name" value="PFN_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036140">
        <property type="entry name" value="PFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027310">
        <property type="entry name" value="Profilin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604:SF0">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00235">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00392">
        <property type="entry name" value="PROFILIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00392">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55770">
        <property type="entry name" value="Profilin (actin-binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00414">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8080643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="157" mass="16809" checksum="7BE5C6A42C2DDECC" modified="2025-10-08" version="1">MSWQAYVDDSLVKSGHIDKAAIISVAGDSVWATSAGFTVRHPPFYPEYTSPVFAFIPNNIDHIPLKPDEMKNIANVVTGAAGAVDKALAEGIHVGGERYVVFRAEDRSMYGRQGRTGILAVKTTQAILVGHYGEGVQAGNAAQTVEALADYLIKVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WFV1</accession>
    <name>A0ABR1WFV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_008791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668448.1">
        <property type="nucleotide sequence ID" value="XM_066813106.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046166"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8080973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="102" mass="11029" checksum="B7B7B849AA22883D" modified="2025-10-08" version="1">MPQLIPQQVNGVRRVNGDNTVPRHGAAVRVPSNINDPPAIAHHGMDPANSPAAYVTQAPRFLEPAMHQSAMMRTASSTNNNTPPRSEATPSPSWPAHHLLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLH3</accession>
    <name>A0ABR1WLH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pua rna binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668856.1">
        <property type="nucleotide sequence ID" value="XM_066809933.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042993"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.10.10">
        <property type="entry name" value="Trypsin Inhibitor V, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021719">
        <property type="entry name" value="Prot_inh_I78"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39600">
        <property type="entry name" value="PEPTIDASE INHIBITOR I78 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39600:SF1">
        <property type="entry name" value="PEPTIDASE INHIBITOR I78 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11720">
        <property type="entry name" value="Inhibitor_I78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9002" checksum="03EB0E7C02E75508" modified="2025-10-08" version="1">MPLVVPGISSTSGDKTEEWTNKLVGKKVSDDAHSEVNFCKKDLPQECRVIEPGMMVTKDFKPERLNVHVKEDGTVSHVQHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM83</accession>
    <name>A0ABR1WM83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669106.1">
        <property type="nucleotide sequence ID" value="XM_066810183.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043243"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="29"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="219" mass="24439" checksum="7378A0F8A8F2CB29" modified="2025-10-08" version="1">MPAVTLPSKPDAVLAYELIPGDAASSLLVVFLNGPGFPQSVWKPTIELFQQQSTVSKRPWLLTYDRYGQGGSSRDPRENWPSKDPGYAHTLDDVTGDLHELIQTLSPDRHSRIVFVNNSIGAQVARRYADRYPTIVEGILFLDSNPGNTNYETIWPNPKDPSFNLEQMTPPGTTLEVYQAAYTKMCTSFSGHAKNAEGFDRRDIKDMLPDPSSPKLKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMH9</accession>
    <name>A0ABR1WMH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_005909</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669147.1">
        <property type="nucleotide sequence ID" value="XM_066810224.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043284"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015033">
        <property type="entry name" value="HBS1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08938">
        <property type="entry name" value="HBS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Tr-type G" evidence="12">
        <location>
            <begin position="383"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="212"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="330"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8084638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="744" mass="80464" checksum="5CADA11AC8DEC09E" modified="2025-10-08" version="1">MSRHQAYRNYDYENDLDEYDGEEAYGEEEEELSPEDKAQMEAGTIQVRDALGPQASKVTTAQIQEALWHYFYDIDKSVAYLVTKHIASPAPKAAKSAPMQKNKGEVAHGTYQTSKHFSFADFFNDMPWGNIPKHREATFIAPLYPRGGLLGGAGTPGKPSKLQQLALARKKKAEEQKAGNADQDVQGTTTQMSQLSVGQDIGANEAAKSPLIMSSSEPDSTPLSRKPGLGTLLADRKRKVGDLGQVEIPPMAKPSPEPSVKSPDEVPAPEPAIPSAFAQTLVGSAPATPKPIPRTSYQLPYMAFTSSVSEAFSGPSPDDVVLSAQAKASNKKLASSSSKKTGGHDAKVDQASEGVKAMNVDDTPLPKSKNLDVLKEYKNSKAKKSVSFVVVGHVDAGKSTLMGRLLLDLKVVDQRTIDKYRKEAESMGKSSFALAWVLDQRVEERSRGVTIDIATNRFETEATSFTILDAPGHRDFIPNMIAGASQADFAVLVVDASTGAFEAGLKGQTREHALLIRSMGVSRVIVAVNKLDTVGWSQERFDEISQQVSGFLVATNFQLKNVSFVPVSGLRGDNMVHKSEDSAANWYTGMGDALLIQPSGEKAYVKSLEVDSEPVEWAVAGQSTVIHLTHIDPIHIRVGDIVCDLKQPISCIDTFTIKALAFDVLMPMQVDVHRGRLHAAGQILEMPATLDKVKGTVLKKKPKVVKPGNIARVVVKLSDKMPLEAGQRIVLRSNGETIAAGLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMR7</accession>
    <name>A0ABR1WMR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-lysine N-methyltransferase EFM6</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Elongation factor methyltransferase 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">EFM6</name>
        <name evidence="3" type="ORF">PG997_006106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669344.1">
        <property type="nucleotide sequence ID" value="XM_066810421.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043481"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03198">
        <property type="entry name" value="Methyltr_EFM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033684">
        <property type="entry name" value="EFM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF152">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EFM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="119"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8084835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="347" mass="38478" checksum="1012EC76C2DCD468" modified="2025-10-08" version="1">MESKTSRSPSPEFSPLAIGTDLAPPRELKAAATTDLDFSGLLADAIQLHEDLKSGNGGQAWPAGMVLAKHMLRYHRNDLQNSRMYPLVCLLPGNQWGVRASGFRLPASSTRGGENLELGAGGGLVGLGVASGCDITQPVYVTDQVNMLPLMEKNVALNKLGSKVQPAVLNWGEPLGSDVINFKPDVILAADCVYFEPAFPLLLATLSDLLALCPSATIYFCFKKRRRADMQFLKKAQKAFQTVELVDQDREVFSRENIFLYSFRKRDVPDQSQWKGYDSSDVQWPSLPRLMLKNAGLGYTDFPGSFSLAVRQPRVLLKFSPILEVVCSRQLRVPTEIRVPRPWFDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN11</accession>
    <name>A0ABR1WN11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669327.1">
        <property type="nucleotide sequence ID" value="XM_066810404.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043464"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8084818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="115" mass="12657" checksum="2C5F46E0BA5842B3" modified="2025-10-08" version="1">MIYSTTENSLLVFNGLFQPSRAISLGRALEDDAIQEELPQSLSRAQVVAIPVQGFSQESDAPLPSQLPTRTYRKPILRWGSLEKDALTRVQGSRIVTRSRAQMASAAATKKKKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNA8</accession>
    <name>A0ABR1WNA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669529.1">
        <property type="nucleotide sequence ID" value="XM_066810606.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043666"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="149" mass="16073" checksum="BCD8AFD2B8B037C8" modified="2025-10-08" version="1">MIEIRGPVEVGALEGRELADVAVAEPVLGHGRRVGREPHAREPDDVLVPALVAVARLRLRVVQVAEPHIPEVSVGEERRPWNRVLIIIPLGMVFENVGQPSVVALLEEVGSIVVVVVLAPDQSIGSDSLVEVELGLHHIKITGSKERPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNV2</accession>
    <name>A0ABR1WNV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669734.1">
        <property type="nucleotide sequence ID" value="XM_066810811.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043871"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="47175" checksum="48505F80E8D165E7" modified="2025-10-08" version="1">MDDLDSIITVPKLSGNGGGLLWPRTGGTGGVEEEASLSPRAASSSSPCPDANNTKIADSKGMEYNLLCGISIIGSDLGSPAPADSLANCLDLCTKTRGTCAGVTYNGTHCHRKDFVGPSAIKSSASLSSGGGGHEDDNSAVAVVPAPSKADCNSLKSCYQSSSSSSSSGSDGSNGKQKQEQEQQQHGFQIYCGQDYKRDDLSKVYAASMTQCLDACAGAFASQGCVGIAYQSGSRGNGVLNCYLKNGSDTKYLVDGRGYDTSAAFMLSESTNGGVLGGVAGVAILCLLVFMLMRRRQKRRTGGNNSDINNHNGSGAAPNPNYFQVPSPSSQHVPPAAPNSSSNFSNFTEGYIVSNPSNAMTQQQQQQQQQQQYFPQPPHQQQYPYQQQQQQPQKPPETFVQSHYEVDASPRAVEVEAPMDRPTEMADQSVWSSHEPKTLTMRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPD1</accession>
    <name>A0ABR1WPD1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_006676</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669914.1">
        <property type="nucleotide sequence ID" value="XM_066810991.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044051"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF219">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8085405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="593" mass="65017" checksum="49DA6CC1C8940B90" modified="2025-10-08" version="1">MWPFSPSYPERILGDIVGQTFDYVIVGGGTAGCAVASRLSEDPNVRVLVLERGKVRDHWLSRIPLISGSLLGGSSLFQLVQRLSERPGNAAGGSEKHRRADLRTAEALGGASRINQMLWTRGAPGMYNAWADELGHPDWSWEKVEPFFRKIEDAAAEESPSGRRTRAYLGRGGPVHLRRHKPQFEIYDHVDKAAAALGLSIDNDVNDPDAPPSGYFALDSTIDRDGARHSAYSAYLPKDLALERRGRLAVCTGVVDSKLEVDVAQHCVRGVHVKPAGSKGGSTFIKAEREVIVCSGAICSPQLLMLSGIGSAEQLEPLGVSVHKNLPGVGSHLSDHHGIPIMMKIPFSQTLHRLQSNILFAIWQVILWIWNKTGILKSGTTAATIYVNTSHIDTQSSTMNTGPYPTMTPPTPPSRRTSPTFYTCLVQPRTTGRVTLASGNDPEQGPLIHYRTLDDEHDRAVARKALRFALHLAEQFAHKSGYRHAAELFYAPGVKTGRRDISKWRDLGDDELDAFAQDTVQSVLHLGCTCRMAAEGEGGVVDDRLRVHGFRNLRVADASVFPRIPAAHTMAATYMVAERCAEFVKEEWKGKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPH1</accession>
    <name>A0ABR1WPH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668889.1">
        <property type="nucleotide sequence ID" value="XM_066809966.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043026"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="364" mass="40212" checksum="F8F65908F5F94CC0" modified="2025-10-08" version="1">MTRNQGLRDNSQDQRWPWTRGRRAGRHQFRPTASYATSNASWLDPQGSAHGRQRQSVQRPLPGIQNPAARQFGQDRNKDGQQLYERPSNTARTSGLSMASGTPVQEGSVCRICKVGRHIPARCIMVLPGTGMSNFCPICPHMDNHTLDNCDHLAEYLADENLLTTLHRRMGPRRVGLPPVYTKLICINKLTRYLGMSMKLLPWSVEHAKKIWQDERETLLDSLDYKSDATLPPSCLELGRENITTHQTRSPCRNGKTPRRSGSNTFALPANQIPAAPPANGTADTIKREEDDSGTSLSTANVEQNTAEGPKADDSMNMGQRETHTATVSSAQAELSHVGQAAVEDSAVRDSSQLNALQQVVTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ76</accession>
    <name>A0ABR1WQ76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006949</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670187.1">
        <property type="nucleotide sequence ID" value="XM_066811264.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044324"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="316" mass="34899" checksum="F7DCD2951C87C735" modified="2025-10-08" version="1">MAPQIIFGTASLGMPMSAFQDAETVQELLHTLQDLAITRLDSGARYPLTARAEPKSFLLSKNFLVDTKIFTDTATDGSGNLTKDAIDRSTVASLHRLRREAVNVLHIHRHDPATPLEEQVRNFIDQISQGRCKAWAASNVPPPILSEMLQLCDKNGWQKPVCYQGCYNLISRGMEKRLLPLLRAHGIKYNAFQPLAAGFLTGKLVNNEHAGTCFGDDHPFGLMVRKLFGDEDLTSAMKKFDAAVKAQGLTPAEVALRWLTHHSSLEDDDGVIIGASKLQQVIDTVGLIRKGPLPDALIPLVEELWSGVEEKRQEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQL3</accession>
    <name>A0ABR1WQL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007096</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670334.1">
        <property type="nucleotide sequence ID" value="XM_066811411.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044471"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="240"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="33945" checksum="7D99E670F641C498" modified="2025-10-08" version="1">MQADGRGLLLGREKEEETASTADSDAGLRADIAIAAVWLGETAYYGPGGGTDMGSVFLHPLQAAAIQGDIQMIETVLGALNEGLSSLDGEEPRPREEYREHAYGHIVLGTALKQGGGRHRAHPWPDLFERARSLVERHIGRPFTYHLGIALTGCTVGGRVDLFRHLLHKAKSRAEAEGGDGKEFRLVDHPESGGPLGLYWNMLAAIRGREEAIVRMLLDRDTGGGGMDVNYVDPTVSANQACTPLLEAVRAGRIDVVRLLLDYGADPNSAGAGDVDVEGRGPVAIADRGSGCVGEVGHLPPLARARGAPGYASDGRGGYGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQU8</accession>
    <name>A0ABR1WQU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">D-aminoacyl-tRNA deacylase</fullName>
            <ecNumber evidence="2 6">3.1.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_006072</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a D-aminoacyl-tRNA + H2O = a tRNA + a D-alpha-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the DTD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="2 6"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669310.1">
        <property type="nucleotide sequence ID" value="XM_066810387.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043447"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="entry name" value="D-tyrosyl-tRNA(Tyr) deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00256">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472:SF5">
        <property type="entry name" value="D-AMINOACYL-TRNA DEACYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="D-TYROSYL-TRNA TYR DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="DTD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8084801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="155" mass="16726" checksum="694ED71D414D5EBD" modified="2025-10-08" version="1">MKAILQRVLSASVTVDKEVVSSIGKGVLVFAAVAPGDTEKEADSLAAKVLKMKLWDDEAGGRWKKSVQDIEGEVLCVSQFTLLASTKKGNKPDFHGAMGGDEARMLYDYFFNKVQQGYKPERVKNGIFQAMMEVALVNDGPVTLELNAGQKASAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWJ0</accession>
    <name>A0ABR1WWJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_002492</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670425.1">
        <property type="nucleotide sequence ID" value="XM_066806807.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039867"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17781">
        <property type="entry name" value="CBS_pair_MUG70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17782">
        <property type="entry name" value="CBS_pair_MUG70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06409">
        <property type="entry name" value="PB1_MUG70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051462">
        <property type="entry name" value="CBS_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108:SF26">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN DDB_G0289609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="680"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="118"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="185"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="288"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="354"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="6">
        <location>
            <begin position="499"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="597"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="611"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="641"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="654"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8087531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="705" mass="76140" checksum="25E381D2D28032C1" modified="2025-10-08" version="1">MSGSTMRGTPSRGGQHRGGNPFNGNSPANPNSNIPRPVLDTQHAASPVPNDAASGVSMSASRQKQSKRDETEKTMDADYYRQAIRRKLENDLNKKKHTTSGRNARMSRKAPPGTVLALKPSPALQIKPSTTVSEAAQLMAAKREDCVLVTDDDDRIAGIFTAKDLAFRVVGTGLIATKVTIAEIMTKNPLCARTDTSATDALDLMVRKGFRHLPVMDENQDISGILDITKCFYDAMEKLERAYSSSTKLYAALEGVQSELGTSQPQQIIQYVEALRSKMSGPTLESVLNGMPPTTVSVRTSVKEAAQLMKENHTTAVLVQDQGSITGIFTSKDVVLRVIAPGLDPATCSVVRVMTPHPDFAPMDMSIQAALRKMHDGHYLNLPVMNDQGEIVGMVDVLKLTYATLEQVNTMQTGDSEGPAWNKFWLSMDNETESMVSGDGSHSHMHTGMASHSMVSHSMARERDRINDSLAPGDSASHVGVDSPEHSIITGNPEPAPAELPFAFKFKAPSGRVHRLQVIASQGISTFVANINSKLGSEVEAIGGIPEVEDGRVGVSGYALSYLDDEGDTVSITTDQDLLEAILLARQHHREKVDLFVHDPSQPPVTVTAPQPIPELPTPPASSAISGGESSRRRRRHHSSEDEDDSEDDDMATVRRRKSKHGHHASAQEKEVIAGVPNELLLPGAIVTLAVVILGVFAISRATSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WWZ7</accession>
    <name>A0ABR1WWZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_002650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670583.1">
        <property type="nucleotide sequence ID" value="XM_066806965.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040025"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8087689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="376" mass="42971" checksum="60D4E249E153E703" modified="2025-10-08" version="1">MLLPALGALLQTPTYGIVKWFLTSRTENEIRAWALQHNVAEIEAPVDFIKADIKTFLHDKCTSVELQHIIGDVVDKSEGNFLWATIMLRALNNSSTDEKKVRQSLKEFPRDLNSLYLRVLHRLSRRKTWKQELARKMLTFLVASVQPLRLSEMSQALTVVTLPNSYQLPQKLSEPSLLEDLCSGLIVFDRSLPGYSEDPMLRFTHKSAHDFLLQSLESYESGHNELCIHTDVATRTRHETYLAMERRALIASFGKEMGVPPAVVRFFTTWRGANRELGLACLRYLSNPQYNKPGFGMGCLDSKDHAFLKYAAVFWHAHFSLSAPTSQDYIQVEAFMKSSAFWNCVAIQAAVAPHQYAVYHRHAGSLFPQHHWIRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXS0</accession>
    <name>A0ABR1WXS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_002913</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670846.1">
        <property type="nucleotide sequence ID" value="XM_066807228.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040288"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF1">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="408"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="510"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8087952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="579" mass="64733" checksum="6D907B41D4062655" modified="2025-10-08" version="1">MAAPSSAAHKPRRKAKKTATYDAIAKPEALVRTPSFPLAAFLWPARGSVSQWEVLPLILMAVGLFRWAAGLWGYSGFQTPPMFGDFEAQRHWMEITTQLPISQWYFHDFQWWGLDYPPLTAYHSWLLGKIGAIIDPTWFELFASRGSHDPTLKIYMRATVIVSEYLIYIPAAVIFVRRYSRLFGVAPWTAWVSLVAILMQPATILIDHVHFQYNTVMLGFVLSSMSSMLAGRHMWAAVFFVAALGFKQMALYYAPAVFSFLLGSCIYPRINVGRFATIAIATAISFAILILPIVLGTLYDASRGIDSQPDLDGPHPPLPIFPQLAEYLDTNAICYPVVEQLVQMVHRVFPFSRGLFEDKVANFWCAINVVIKMRKYPAVLLQRISLAATLAAIAPANFILLIRPRKELLPYAFAATAWGFFMFSYQVHEKSALLPLLPMTILLAGNQGLGKDIRAWVGFANLLGAWTMFPLLSRVDLKVPYAVLTLLWAYLLGLPPTSTSAYFQEGQSAWLQWSTAIVHGAFYLLMIVWHGLAQFVAPPLISLTCGSSRMSESALLASRCVISGVLANWSRKAVYLQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXS5</accession>
    <name>A0ABR1WXS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002894</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670827.1">
        <property type="nucleotide sequence ID" value="XM_066807209.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040269"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.80">
        <property type="entry name" value="ATP synthase, gamma subunit, helix hairpin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="ATP SYNTHASE GAMMA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693:SF22">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT GAMMA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039089">
        <property type="entry name" value="ATP_synthase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="ATP synthase (F1-ATPase), gamma subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8087933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="300" mass="32630" checksum="5C5B63A697063D5D" modified="2025-10-08" version="1">MFSRAARPALRAGAAAAAIPARTANNAATYATLREIEGRLKSIRNIEKITKTMKIVASTKLTRAQRAMNEAQNYGAASNEVYDAAETKPLEGEEKKPLYIVCSSDKGLCGGVHSGLSRWVRRNINHGEADLVVIGEKARSQLGRTNNQDMVLSFAGVGKDVPTFADAQAIADQIVQLQTQYSGIKILYNKFINATSYEPTVIEAFSEEAIAASPNFSAFEVDEELIPNMREYALANSLYWALAEGHACEISARRNAMDNASKNAGEMINKYQILFNRTRQAVITGELVEIITGATASADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYK9</accession>
    <name>A0ABR1WYK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_003212</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671145.1">
        <property type="nucleotide sequence ID" value="XM_066807527.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040587"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12418">
        <property type="entry name" value="RRM_Aly_REF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF82">
        <property type="entry name" value="THO COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13865">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="37"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="142"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="189"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8088251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="269" mass="30191" checksum="30B9B0A7AD4BA3C4" modified="2025-10-08" version="1">MADFYISDSLRRTTSRRSQPITWTFIIVRLHFDARGTKVKVDNLHYELTQEDLEGLFGKIGDVTKVELLYDRAGRSEGTAYVTYNRSDDARRLFANLTAPTQRTWEINSLYSTGQPIRLSIMPSAPRRNPFDSAYMPGRSLADRITVPGGRSRSLSPNRYSNRDRDVDRYVPGGRSGGRSRSPMHRNRRGGDGRGGDRGRRPGARREAREKEDRDGGERKARGRPKKTAEELDAEMADYFGPGEHATSAPADIAPATDAPALDDIDMIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYV8</accession>
    <name>A0ABR1WYV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amino-acid oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671215.1">
        <property type="nucleotide sequence ID" value="XM_066807597.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040657"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF342">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="335" mass="37334" checksum="4D713E7EE294EF14" modified="2025-10-08" version="1">MSYVDNNHQHIDVTVQGEEDKPRRFDAVFNSAPLGAMQQMGLEGLKLNWGTKQAIRSLGYGASCKIGVRFRSLWWIHKLGIRDGGQAKTDLPIRCCVYPSYNMHDPPEQPGVLFVSYTWSQEAERIGALISRESPDKEEALKRVVLHDLARLHSSTDAAYEDLKHTITAEYLDHYAYNWYADPTSVGAFAYFGPGQFQKMYPSIVQSHGKHVIIGEAASSHHAWVVGALESAVRGVYQFLWQHSRVSEAAHRAAEDYAADRVPMPFGPVPAEYDRTQDIRVPDGVDDAAVPSPRGELARQQAMMEEIRLKQGGDFLDPSIVSERDVAPILAVVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZA5</accession>
    <name>A0ABR1WZA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003417</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671350.1">
        <property type="nucleotide sequence ID" value="XM_066807732.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040792"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="27"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="73"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="56524" checksum="B7B0456733373A81" modified="2025-10-08" version="1">MSSADTVPFHEKPDLCQLLLSQVSTGNTLRVRKSRTPGAGSGLFTESAVPAGQEVFRSKPAVTCVPDSLSTVCDFCYANNANRVLPSGRFRTRRDPVEALVDCTGCHICNYCTESCRNTAFEAYHKYECASFLKSGGLGIRARALYRILIHKKHGLLPDHQWQGLMTLMPHQSGHQQGPETETLSRIAKEAKAYTETALDIDTIERIYCVILTNSMAIRLPGQSAVMGTAVDVVGAIMNHSCDPNVLISFDGNELLVRTLRAVEAGEELAHCYTDVQSDVLLRQKLLQAEYFFGCTCSRCQSELAEHECVTHGDEAKTQSIRAAQENLFASMNEAVSGFTLSGKPVDVDSLADHMEELADKAYPTGEWPPSLEPLPSIYKTLGRLNQAHGDPIAAIEYCIRGCAHTKRRAGEPWMVDLFELVQVLTAPPFPTTAELWDVFHGYLHELLRLAQGNCGHDVSYTRAIRSWHDAALKYADGPLPGTQEFADQFHAAHRKLLLWAGVAEDQWTIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X067</accession>
    <name>A0ABR1X067_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_003766</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671699.1">
        <property type="nucleotide sequence ID" value="XM_066808081.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041141"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="44"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8088805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="166" mass="17922" checksum="144F2D81E175DC8C" modified="2025-10-08" version="1">MIIPPPSVIASWPKPNYANPESQGPAGVGIGSTFVALVTIVLLLRLYTRRWISKGFGLDDILIVCAYVPALAFTIIGIVGERKLGWGRHVWDVPPGDTAASLKTSLATLILFDAATSLTKLSMLAMLYKLTTASADKKMNNVILGLSALISLNAFIFVIVEMFQCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0B7</accession>
    <name>A0ABR1X0B7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secretory component protein SHR3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_003829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671762.1">
        <property type="nucleotide sequence ID" value="XM_066808144.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041204"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013248">
        <property type="entry name" value="Psh3/Shr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228:SF1">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08229">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029187">
        <property type="entry name" value="Shr3_AAP_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00786">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8088868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="24215" checksum="58ADA5AAD7AD1DD7" modified="2025-10-08" version="1">MPNSTPAPAPAPRPDSHSGSSSFATFLIIGPTCFFLGIIFSQFPYDFPLLWTSEPVAAAFLDQLEVHLKFVHQSPPLIARILHIAIGTGFLGFFVKLFKPSESNMLFDGASLVLYLIGVGIYIANIVKGLRTVSAGIWNEEGFAQTVDGPLTGEVVLGREDSLKVMAASNTILALVLVGILVLQAGQWYAERKDREEREGLEKAEAVVQQQQKVSGAQSKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0Z3</accession>
    <name>A0ABR1X0Z3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671921.1">
        <property type="nucleotide sequence ID" value="XM_066808303.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041363"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12611">
        <property type="entry name" value="RRM1_NGR1_NAM8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12613">
        <property type="entry name" value="RRM2_NGR1_NAM8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12346">
        <property type="entry name" value="RRM3_NGR1_NAM8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF10">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="61"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="154"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="299"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8089027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="421" mass="45208" checksum="D2D036959DAE363F" modified="2025-10-08" version="1">MDNFNPYNGKAPSNGSGSQGEGGSQGGGPGLPPSGLPIAPPNGQSGGDGSTGFPSADAARQTLWMGELAGWMDESFIRSIYSSAMNENVQVKIIRDRHSGNAGYCFVEFSNPEAAQKALALNGTPVPNTDRVFRLNWASGGGLVDRRDTRSPEFSIFVGDLGHEVNEFVLVALFQARFPSCKSAKIMTDQQTGQSRGYGFVRFSDEQDQQRALVEMQGVYCGNRPMRVSPATPKNRSHQGGQFQNFGNPAMMPPQGGMQPSGGMNNQWMAQQQPNYGFQQGGGGFNPMAMNQFTDPNNTTVFVGGLSGYVTEDELRSFFQGFGEITYVKIPPGKGCGFVQFVHRHAAEMAINQMQGYPIGNSRVRLSWGRSQNNSGVGTPYRPAPPPPHYWPPGPPAPLVLEVLSAVLASAAMDKALLLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X166</accession>
    <name>A0ABR1X166_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_004134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672067.1">
        <property type="nucleotide sequence ID" value="XM_066808449.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041509"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8089173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="75" mass="7907" checksum="5FCE8C8EE636BC23" modified="2025-10-08" version="1">MAGSWKLETEAVRRANDLQLLSAGSGCAELLTGYFERAFVTKSRGSSVPQFCGGGVAGAWRPLAADLQAEPEATF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1U7</accession>
    <name>A0ABR1X1U7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dihydrofolate synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_004354</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672287.1">
        <property type="nucleotide sequence ID" value="XM_066808669.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041729"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF0">
        <property type="entry name" value="DIHYDROFOLATE SYNTHETASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8089393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="41855" checksum="FA1F1637189B5468" modified="2025-10-08" version="1">MIELGLARIQTLLQKTPQTWKAIHVAGTNGKGSICAYLTAMLRANNISCGRFTSPHLIDRWDCISINDHPVLEAKFRHYENLVKVRNDQLQAGATEFELLAATAFEIFEAEQVQVGVIEVGLGGRLDATNVLRNKAVTIISKIGLDHQAMLGNTLEEIALQKAGIMRATVPCVVDAKSSDFAQLFQGTFEPHQVQNLTAAHEAFKLAYPQYAQSADILMPAIMNMKWQGRLELLDITSLVKRPREVLLDGAHNPQSAKVLAEYVDKHYRVDHPPRSVTWVLAASDGKDFAEVSKHLIRPGDAVAAVEFGPVDGMPWVRAMKTDALLEMMPHESLSSQHNARQDVLGSIEWAVATAGGGPLVIAGSLYLVSDVLRLLRDKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X213</accession>
    <name>A0ABR1X213_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004428</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672361.1">
        <property type="nucleotide sequence ID" value="XM_066808743.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041803"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032108">
        <property type="entry name" value="CLIP1_ZNF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF83">
        <property type="entry name" value="TIP ELONGATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16641">
        <property type="entry name" value="CLIP1_ZNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CAP-Gly" evidence="8">
        <location>
            <begin position="145"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="87"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="218"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="547"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="647"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="745"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="384"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="547"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="577"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="605"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="618"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="647"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="665"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="695"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="748"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="845" mass="91362" checksum="916C3B03BEEA4B44" modified="2025-10-08" version="1">MASMAAPTTSLPTPQSRQKTLSRGNKKSAIGTASTPNLNSLYAAHSRLGPGAGALARKASFAALTPGSLAAIPDDSESYAIHSVLNSDFDHRNNTTNNNPHPPTSPRRMAPATPARGASALDHDLAVGDAVDVPGNMHGTVRFVGSVAGRKGVFAGVELHPDYAARGKNNGDVDGISYFTTLTPGAGIFVPISKLFKRDNGGSSFPLTPSGNSSLAALRVSSQHSTSFTPPTPSVPKFSQSVGPGRAPSPAGRRSRTSLARPESPVRRLQLSPAPRQGLAAPGPPKTPVPSRYGTPSIGKFSASVRGTTGDPNKRLERKPSIVPRSASAMGQASSLFGGEDEATPLGRATPVGRSMNNGSIGSMSSLRMRPSSRAAAANDEEIERLRSQLDDRDRQLRDQASALAEMESSVTELTSLMEHGDFGKPRPNNLDDKDSAQLRALLREKNEKVALLTAEFDAHRADFRSTIDTLEMASTETQRVYDARIRELEQEIHEMQERGEDVDSVARQLKQLEELVQELEEGLEDARRGEAEARGEVEFLRGEVERTRTELRREREKASAASNGGPDGPDTLSLSKELEKKEDEIRGLKAIIHSLSRDNESPDKTPTQPQRTQSFDSSHHGSTEARIAKEKLEREVNELRGLIETKSSREEELEHELETLRRGSASTQRTSQMTIGSADRSSYRDSKGTIIPARETRSPEHKRVPTLETMPESDAYSSVTESSTLWCEICETAGHDILTCTNMFGPQQNQSQSQDQGQDQGQDQGSPKSAKTGKDAGPEEAEDLSHLNVPNAEGKSMPRPLTPVKSTPATNPRRLIGVVDPEKWCALCERDGHESIDCPLEDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X291</accession>
    <name>A0ABR1X291_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transmembrane amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_004423</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672356.1">
        <property type="nucleotide sequence ID" value="XM_066808738.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041798"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF20">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="92"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8089462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="536" mass="58818" checksum="F0381DC4B55E569F" modified="2025-10-08" version="1">MMTDSASGLPSKEAVDERRVDDYDAEAAIRDTKPTGWSAWFGGPNVKIGPRIAPVVAPLNANMNTSDSDIDSKDILMKQIASEENSAIQYRTCSWQKTAALLFSEYICLAIMSFPWSYSILGLVPGLILTAVQALIVLYTSLVLWEFCLRHPEVRDVCDIGQMLFWGKKWAWWATAIMFILNNTFIQGLHILIGAKYLNTMVGPDSSSVHCQTVAFGIIVALISWICSLPRTFEMLSKLGTASAFFTFVSVILATVFAAIQANPANYHEAPGTSPSGAALPFGSPIVTAIPVAGTTFVSGLNAFLNISYTFIGQITLPSFIAEMKEPRDFPKALWACTIAEILVFSIVGGVTYAYVGNQYMTSPAFGSLEDLYKKVSFSFMIPTLIFLGVLYASVSARFIFFRLFQGSRHKNDHTLIGWASWSGILLATWILAFIIANVIPFFSSLLSLMSSLFDSFFGFIFWGVAYFRMRKADGSVALFKDRSIRGWLEGILNIIIILTGLFFLTAGTYASVEGIIEEFEAGTVGSVFQCASNGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2J2</accession>
    <name>A0ABR1X2J2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_004599</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672532.1">
        <property type="nucleotide sequence ID" value="XM_066808914.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041974"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045005286" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="30"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="256"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8089638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="619" mass="66140" checksum="52C52852CEBC7B71" modified="2025-10-08" version="1">MLRLSLLTAVGCSISPAFSAPVTGDASSAAPTVTVKNGTYSGIHSESYDQDFFLGMPYSQKAVRFTQAESLNSTWEGAREATAYPLHCVGYGGDEVGYELSEDCLYLNVVRPAGLSETADLPVAVWIHGGGLVMGGSADKRYNMSFMVENSVKQGTPMIGVSLNYRVSAFGFLSGKEVLDAGLSNIGFHDQRLALRWVNENIASFGGSPEKVTIFGESSGAESVHAQVFAFNGKSCHVIVDDISIQVYTYRANADLTSGRDDGLFRGAMAQSGFGQSIFRFPGGLNGTVKRQETFDNLVKNVTSCASTVGTADAIPCLRTAPFEEINHALNVSSVGPWAPQFDGDFFADHPFNQLNNGKFPKIPILIGENTDEGSAFGSGRGPNGGPINTDADFEWSIRNGLLGSQAAEASGKSIDVLTSELMALYPNIQSLGIPSLASWPEVINSTTEGVEKMGLQYRRGNALYGDVMMHYARRRANIAWAKAGLPSWSFRFDVTTPGSPGSVSATHFQEVAYVFHNLGGDGYTEDQKPFPADAPGIAANRDLALTISSAWVNFVTGLDPNGDNVKPAWPRYDLAAGGGVGENMVFAVEGQGSHAEIDDYRAEAINWMIENSLTVFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4X1</accession>
    <name>A0ABR1X4X1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673347.1">
        <property type="nucleotide sequence ID" value="XM_066809729.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042789"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053018">
        <property type="entry name" value="Elsinochrome_Biosynth-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="343" mass="38175" checksum="8D64B5D864EC05C9" modified="2025-10-08" version="1">MSLGISLLIGALSQHATLGLYHFHIVYDVVNFTGVSAAAAVATAFKRPEGFFFSKLLMSVYMCLYLAFTIVFGSRLRWWDDGISGQCYNTNMVSAPDAAHPNVDIIYLSITALYLFSSLILSRRAAPGNSPSAMERLERTATRLPFPLAYVARRFVARYKSYEQYIAKARQYLVRPAKPRPEKAETSLSAAGKTSRFQQLRESLGDNGSHSLNPYESSYGVRSNILEVAMIQYPVHGYMVYALRASNERFLSGSSENEWGFGQIVALVLVVTTLLECVKAWARYQLSKDSEEKYVSTGTDPPSSQFLRTWLLAKDEPSGPVLPSNRSKGLGRRQSLPLDFKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4X3</accession>
    <name>A0ABR1X4X3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_005423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673356.1">
        <property type="nucleotide sequence ID" value="XM_066809738.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042798"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8090462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="219" mass="22752" checksum="7D0448D8EC4D92F1" modified="2025-10-08" version="1">MSEGSSARHVSHVAVYNGNDHNGQGLQHNGLGINNTHHQRDVNLWFNEHRGQVLTTIAIVAIVAMVSLGLGLGLGLKTGSNSPTGNDHPTSPGPAGPGLPSSTTAQGIPSQTETIPSVTKSANPYECRFSCDQSYQDEHGCHPNCPGAPCPDDTGCQDPYPCIPRITSGTTKTSAGLVLSSCCNTGCKETWTCHGACSLDLKCVTATNFTAASTCTKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7E0</accession>
    <name>A0ABR1X7E0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673404.1">
        <property type="nucleotide sequence ID" value="XM_066806108.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039168"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02182">
        <property type="entry name" value="GH16_Strep_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046341781" evidence="1">
        <location>
            <begin position="19"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="46"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="349" mass="37849" checksum="5BD50B19D9D0D681" modified="2025-10-08" version="1">MWSNTLLALAPFVASSLAWTPPSYSGFNLRWTDAFGGSGGASPDQGNWNIITGDLNVNNELETCPLPKFVYFNSSSTRNLQLSGGNTLQIVPWKGGGTHGWTSGRIESKYTFTPAAGVVTRVEASIRFGSNPISAKQGLWPAFWMLGNSIRNGVQWPGCGELDIMETVNGLLTGYGTVHCDRAPGGICQETQGLGKSIGIPNQEFHVWRLEWDLTSSNWQSQSIKWFLDGQAYHTLTGGNIGNQAVWNTLAHAPMFFILNMAVGGGWPGNPNGVTQDGYGAMMEVGYVAHYQRNNMAAMKFANGNSSSAETDYPNTNTPVAPEMMALLDKEAPSISANTITRMARRFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7Y0</accession>
    <name>A0ABR1X7Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aflatoxin regulatory protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_001932</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673543.1">
        <property type="nucleotide sequence ID" value="XM_066806247.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039307"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013700">
        <property type="entry name" value="AflR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08493">
        <property type="entry name" value="AflR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Aflatoxin regulatory protein" evidence="7">
        <location>
            <begin position="16"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8091571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="250" mass="27256" checksum="0A03B83EF554974B" modified="2025-10-08" version="1">MHGTSLEFDEATIPPRPRKSNGPPTPTKPSGLTIEAVMAQNDAIIESATEMLECGCAEDDYLLFIMPLMVLKVLDWYAAAARPMSNPASLSLPSPLSSKDASPPPPSPPRPGTASSEMMPLPMAEYTEQVLQGPSIVIIDGYLIDGEDSERMAAQLVLSKLHRAQRLVNQLSHKLKVQAEKTKKLHAEASSDAGRGDVASSLMQGVEASGGGMRLPLSYSVLDELSVDLRRRLRRLSSEIVEQLRRHRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7Z3</accession>
    <name>A0ABR1X7Z3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673462.1">
        <property type="nucleotide sequence ID" value="XM_066806166.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039226"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032857">
        <property type="entry name" value="ALKBH4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463:SF1">
        <property type="entry name" value="2-OXOGLUTARATE AND FE-DEPENDENT OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463">
        <property type="entry name" value="OXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="86"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="263" mass="30225" checksum="7D8F1B7A4E17F62E" modified="2025-10-08" version="1">MEELPMEPRGLFYQENFVDPAHEAELVRLFREELDWPVRPPGTRLSLHYGYTFDYKTFGVDPDIPFKPFPDWLRPLIPQTVRGGLPPAQVCLQYYPPGAGIPPHVDTHSAYDELYSLSLGSAVMMQFRRPPSIAAVATPSGEATGDAGEEEEDKRAELDLVPRSLLEMRGDSRLHWTHGIKKRKTDTLPDGTVRPRQDRWSITYRWLRERAVDEDTPAECECGNARLCDTAQRRVGIEREYRWKQQEQEKKQEDTGTLREAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X812</accession>
    <name>A0ABR1X812_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673536.1">
        <property type="nucleotide sequence ID" value="XM_066806240.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039300"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="35366" checksum="8F665272D7DC5DA3" modified="2025-10-08" version="1">MGFFYSQFFKTPPYPTGSYQGKTIVITGSNTGLGKEAARHYIRMGASRMILAVRNLDQGHEAKHGIEASTGCAPDVIQVWRVDMSSYASVQKFAARFNAELDRVDIFLANAGCAKLQYTTAEDNETQITVNVVATFLLAMLVMPKLKETALRHQTRPVVSITSSGAYQHTTFPQRTAPEGKLFATINDKATAESHWAEQYPLSKLLEIFLVRAFAERYPAAVFPVTLSCVSPGLCHSGLAREQNTLGFRALKFVLARSTEVGSRTLVHAGGAREAHGQFLEDCEVDPLTEMVTGNKEVQDRLWVELVEKLKAIRPDAMDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8Q3</accession>
    <name>A0ABR1X8Q3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_002165</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673776.1">
        <property type="nucleotide sequence ID" value="XM_066806480.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039540"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF187">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="493"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="50"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8091804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="537" mass="57863" checksum="2159E3974B8CE18A" modified="2025-10-08" version="1">MNNNHHKGGSAVADVPTTSSSSQANIVGSDSATPDEEPPAFKPTLQFWLVFLALLLATLLSALDGAIVATALPTISSDLEVGPDFVWVANVYFLTGAVLQPLFGQLSDLWGRRPIFIAILAVFTFGSGLCGGASSGKMLIAARAVQGVGAGGINMMVDLILCDLVPMRERGKYLGILFGVIGLFSAMGPLIGGALAQSGQWRWAFYLNLPIGGVCILITLFFMKLQSRVGGGFMQKLRRVDWVGVTILTISCIAIMYAYRHTLAGGLLGLIIFALFEGTPFVSEPVTPYHLFANRTSAIAFIVTFLQSMMGLYMIYVYALYFQAVLGANQTLSGVYLIPTVISFPLFSAIGGVLMTKYGRYKPLHLIGFAFLTLGCGLSSLLGSDSNPAEWVFFQLFLGIGAGLTMAVLLPAVQAQLQESDTALSTGTWAFIRSLGVIWAVTIPAAIFNNRFGQLLYTIDDPAARAMLDNGNAYAHGTAALVREVYSRSIQRVWQIGVVFSGVCFLLSLFEKETSLRRELETDFGLQEEKKETQVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8R1</accession>
    <name>A0ABR1X8R1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1308 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673828.1">
        <property type="nucleotide sequence ID" value="XM_066806532.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039592"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010733">
        <property type="entry name" value="DUF1308"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13379">
        <property type="entry name" value="UNCHARACTERIZED DUF1308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13379:SF0">
        <property type="entry name" value="UPF0415 PROTEIN C7ORF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07000">
        <property type="entry name" value="DUF1308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1308" evidence="1">
        <location>
            <begin position="338"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="590" mass="65012" checksum="B24F9854A960D891" modified="2025-10-08" version="1">MAMDASHQDLFERARTLQSELEQFAAHVRDTRGTATQLYSRLLSLSADVQTDARALERRIQQVREADDPGVQDVNALSGANLPFYEAIWETAKRSRDVVDIRCKICINPTCKLPLAPGNRIMPSLGTQSSSKLRHITVDVITDGGLAWYKVSTTTNRKLIYDLAKEAVYCGDSDEEDADPFEDETADLDIPLLKIAKDMAQAAANHRIRTKQPKTYIILPRVFEGETVQVDKLLQLCRKTGVTILCGADLPPVPSFGTTAVVPKDMADLPRRLDDPDLAVEPDSEPVLHGISPMDTLEACMVTNGVDDLLHISDGRISAMEGETTLPDVSPQSVMKVLNIDTSVLVALASDFSHTAVPRQGWYNRHHVAHWEQEKKEHFLPAHLYPTLGDHELVCVTEAAETLRHIVKTMGTPAEKARARVILGDDNDGNETGQKELVRALQDLSIYEVPSNFKLPVRAVDKNKNGCQKQLPDASKHVLAGQLNPGRSVFAYGWAAGVTSITCNAAAVKQMATELERRPGSTIPPGLPSGHFRRLGRLWEHQSPKGSHPCVQRNTSVTAKPMGAHAVWTSFTPKRITRFWTDLGMLSTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8U5</accession>
    <name>A0ABR1X8U5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_002237</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673848.1">
        <property type="nucleotide sequence ID" value="XM_066806552.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039612"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08192">
        <property type="entry name" value="MAR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF107">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="3">
        <location>
            <begin position="34"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="4">
        <location>
            <begin position="212"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8091876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="416" mass="44359" checksum="95C27E9F57386359" modified="2025-10-08" version="1">MPQETHRPAFAGRDKPSVSYGLPFPLTLLHHAGSTFGATRLYVLCSASLARNTPHLTALKDTLNSKVAGVRVGLRPHTRWSEVLEVVREARDLDCDLLVTLGAGSLTDAAKIVSLALANDASTPEDLEGLLPDPSVGSRPDHTASKNVKPARVPVVCIPTSLSGGEYSAFAGATKDADGRKYSFSGPAMSPPALVILDPSLVMSTPAHVWLSTGVKAVDHCVETLCSLKSDDAADADARHGLARLVPGLLRCAKDNDGKDEDARLVCQLGAIDAMSAATRDVPLGASHGIGHQLGPAGVSHGETSCVLLPAVCKFNYQRDANRERQHAIQKLLWYDQEARALFKQQGLTQESADLGDLLDVFIRTLGMPRTLKEFGIGKDKLGGIATHSLQDRWVKTNPAPLDEQGVLEILKMVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAA1</accession>
    <name>A0ABR1XAA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Pentafunctional AROM polypeptide</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="19">3-dehydroquinate synthase</fullName>
                <shortName evidence="19">DHQS</shortName>
                <ecNumber evidence="19">4.2.3.4</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
                <ecNumber evidence="19">2.5.1.19</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="19">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
                <shortName evidence="19">EPSP synthase</shortName>
                <shortName evidence="19">EPSPS</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Shikimate kinase</fullName>
                <shortName evidence="19">SK</shortName>
                <ecNumber evidence="19">2.7.1.71</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">3-dehydroquinate dehydratase</fullName>
                <shortName evidence="19">3-dehydroquinase</shortName>
                <ecNumber evidence="19">4.2.1.10</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Shikimate dehydrogenase</fullName>
                <ecNumber evidence="19">1.1.1.25</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="26" type="ORF">PG997_000279</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26 27">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19 20">The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19 20">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:21257"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19 20">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19 20">
            <text>shikimate + ATP = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19 20">
            <text>shikimate + NADP(+) = 3-dehydroshikimate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="19 20">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="19 20">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="19 20">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="19 20">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="19 20">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 19 20">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 19 20">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="19 20">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="19 20">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="19 20">In the 2nd section; belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="19 20">In the 3rd section; belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="19 20">In the 4th section; belongs to the type-I 3-dehydroquinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="19 20">In the C-terminal section; belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="20">In the N-terminal section; belongs to the dehydroquinate synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="19">In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="19"/>
    <dbReference type="EC" id="2.5.1.19" evidence="19"/>
    <dbReference type="EC" id="2.7.1.71" evidence="19"/>
    <dbReference type="EC" id="4.2.1.10" evidence="19"/>
    <dbReference type="EC" id="1.1.1.25" evidence="19"/>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674367.1">
        <property type="nucleotide sequence ID" value="XM_066804594.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037654"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00502">
        <property type="entry name" value="DHQase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08195">
        <property type="entry name" value="DHQS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01065">
        <property type="entry name" value="NAD_bind_Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="entry name" value="Enolpyruvate transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03143">
        <property type="entry name" value="Pentafunct_AroM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018508">
        <property type="entry name" value="3-dehydroquinate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056179">
        <property type="entry name" value="DHQS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008289">
        <property type="entry name" value="Pentafunct_AroM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010110">
        <property type="entry name" value="Shikimate_DH_AroM-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
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    <dbReference type="NCBIfam" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
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    <dbReference type="NCBIfam" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
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    <dbReference type="NCBIfam" id="TIGR01093">
        <property type="entry name" value="aroD"/>
        <property type="match status" value="1"/>
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    <dbReference type="NCBIfam" id="TIGR01809">
        <property type="entry name" value="Shik-DH-AROM"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR21090">
        <property type="entry name" value="AROM/DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR21090:SF5">
        <property type="entry name" value="PENTAFUNCTIONAL AROM POLYPEPTIDE"/>
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        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24621">
        <property type="entry name" value="DHQS_C"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
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        <property type="entry name" value="EPSP_synthase"/>
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        <property type="entry name" value="SDH_C"/>
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        <property type="entry name" value="Shikimate_dh_N"/>
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        <property type="match status" value="1"/>
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    <dbReference type="PRINTS" id="PR01100">
        <property type="entry name" value="SHIKIMTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
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        <property type="entry name" value="Dehydroquinate synthase-like"/>
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    </dbReference>
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        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS01028">
        <property type="entry name" value="DEHYDROQUINASE_I"/>
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    </dbReference>
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        <property type="entry name" value="EPSP_SYNTHASE_1"/>
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    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="14 19 20" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 19 20" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 19 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="15 19 20" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 19 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16 19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12 19" id="KW-0521">NADP</keyword>
    <keyword evidence="8 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 19 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 19 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 19 20" id="KW-0862">Zinc</keyword>
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        <location>
            <begin position="86"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="3-dehydroquinate synthase C-terminal" evidence="25">
        <location>
            <begin position="200"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Enolpyruvate transferase" evidence="21">
        <location>
            <begin position="412"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="23">
        <location>
            <begin position="1290"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="domain" description="SDH C-terminal" evidence="24">
        <location>
            <begin position="1536"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="region of interest" description="3-dehydroquinate synthase" evidence="19">
        <location>
            <begin position="1"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate dehydrogenase" evidence="19">
        <location>
            <begin position="1285"/>
            <end position="1570"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for 3-dehydroquinate synthase activity" evidence="19">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for 3-dehydroquinate synthase activity" evidence="19">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <feature type="active site" description="For EPSP synthase activity" evidence="19">
        <location>
            <position position="828"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for 3-dehydroquinate dehydratase activity" evidence="19">
        <location>
            <position position="1175"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity" evidence="19">
        <location>
            <position position="1203"/>
        </location>
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    <feature type="binding site" evidence="19">
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            <begin position="53"/>
            <end position="55"/>
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        <ligand>
            <name>NAD(+)</name>
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        <location>
            <begin position="92"/>
            <end position="95"/>
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        <ligand>
            <name>NAD(+)</name>
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            <begin position="123"/>
            <end position="125"/>
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        <ligand>
            <name>NAD(+)</name>
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        </ligand>
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        <location>
            <position position="128"/>
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            <name>NAD(+)</name>
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        <location>
            <position position="139"/>
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        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
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        <location>
            <begin position="148"/>
            <end position="149"/>
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        <ligand>
            <name>NAD(+)</name>
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        <ligand>
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        <location>
            <position position="161"/>
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        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
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        <location>
            <position position="170"/>
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        <ligand>
            <name>NAD(+)</name>
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        </ligand>
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        <location>
            <position position="171"/>
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        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
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        <location>
            <begin position="188"/>
            <end position="191"/>
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        <ligand>
            <name>NAD(+)</name>
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            <name>NAD(+)</name>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
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        <location>
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        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
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            <begin position="273"/>
            <end position="277"/>
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        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
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            <position position="280"/>
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        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
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        <location>
            <position position="280"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
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        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
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        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
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        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
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        <location>
            <begin position="873"/>
            <end position="880"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00004842"/>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="HAMAP-Rule" id="MF_03143"/>
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            <dbReference type="PIRNR" id="PIRNR000514"/>
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            <dbReference type="Pfam" id="PF00275"/>
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            <dbReference type="Proteomes" id="UP001433268"/>
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    <sequence length="1570" mass="170572" checksum="26561A0237899DA0" modified="2025-10-08" version="1">MAGQHDGPAPEGPTRISILGSDSIIVDHGLWKNYVAADLLANVKSSTYVLITDTNLEERYIPVFRDAFEKAVAAANLPAAPRLLTYTIPPGETSKSRETKTEIESWLLQNECTRDTVIIALGGGVIGDMIGFVAATFMRGVPFVQVPTSLLAMVDSSIGGKTAIDVPEGKNLIGAFWQPRRIYIDLVFLETLPIREFINGMAEVVKTAAIWDEKEFTFLEENASTILEAIRSKTADLSERINPIKSTLKRIVLASARTKAEVVTQDETEGGLRNILNFGHSIGHAYEAILTPQVLHGEAVAIGMVKEAELARYLGIMRPGAVARLVKCIASYDLPTSLHDKRIVKLTAGKRCPVDVLLQKMAVDKKNEGKKKKIVMLSAIGKTYEPKATVIDDSAIRVVLSPATRVQPGVPKGLSVSVAPPGSKSVSNRALVLAALGKGTCRVKNLLHSDDTEFMLNAIGQLNGATYTWEDAGEVLVVSGKGGQLQASEEPLYLGNAGTASRFLTTVVALCSPAKATSTMLTGNARMKVRPIGPLVDALRTNGVEIKYLGQEKSLPVEVNAANGFNGGVIELAATVSSQYVSSILMCAPYAKNPVTLKLVGGKPISQPYIDMTTAMMKTFGITVTRSDTEEHTYHIPQGVYQNPDEYVVESDASSATYPLAVAAITGTTCTIPNIGSKSLQGDARFAVDVLRPMGCTVEQTDYTTTVTGPEPGTLKGLDYVDMEPMTDAFLTASVLGAVASGVTRITGIANQRVKECNRIAAMRTQLAKFGVESGELEDGIEITGKNYQELTEPADNVFCYDDHRVAMSFSVLSVLSPQPVTILERECTGKTWPGWWDVLAQSFKVGLAGIDAEPEHETAKKPAAGPSVFIIGMRGAGKTTAGRWMANILNRPFTDLDDELERRAGMTIPQIINESGRGWEGFRKDELDLLADVIKNQAHGHVFSCGGGIVEMPEARKLLQNYHRNGGTVLLIQRHIEQMIEYLMRDKTRPAYSEQIREVYERRKPFFQECSNYEYHSPYLAGIDEAPEDFKNFVLLICGQSKHFERIKRKRPSFFVSLTVPNVSSASQVIPRVVVGSDAVELRADLLEDLSPEFIASQVALLRSRAKVPVVFTLRSKAQGGRFTYESEDELLPIYRAAMRVGVEFVDVEMTLSPETLETITQSKGYTRIIASHHDPEGKLSWKNGGFQAWYNKALQYGDVVKLIGFAKTTDDNFACVKFRQNMLAAYDTPMICLNMGTIGKFSRIANGFLTPVSHPDLPFKAAPGQLSAAEIRAGMALMGELEAKQFYLFGKPISASRSPALHNALFKTAGLPHTYQLNETDDAASVKELIRSPDFGGASVTIPLKLDMMKLVDEVTDSAKIIGAINTIVPGPDGKGGVRLVGTNTDWMGMVYTLRGKGVMAQDPTATPSSAMVVGSGGTTRAAIFALHSLGYSPIYIVARNTNVVEGLCTSFPADYNLESPKDANQVKVLPTVIISTIPGDRPIDPSIESVVSDVLTQPKNSNHSHVLLEMAYKPTETPLMKIAQPEGWTTIPGLEVLCSQGYYQFQLWTGITPIFQDVRNAVLGTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAD2</accession>
    <name>A0ABR1XAD2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674438.1">
        <property type="nucleotide sequence ID" value="XM_066804665.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037725"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053018">
        <property type="entry name" value="Elsinochrome_Biosynth-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="308" mass="35021" checksum="0A7B5079DC074719" modified="2025-10-08" version="1">MDYTLADEEATFENITITYCDNVGEAKPDIAGLGVLISFAGQALLSLFLAAWIIILSKKGHLHLHHHPEGSDEHERRKKRIEFLSDVVNIGNDLQVLLGIALMTNSHGTADHGLDQEERTGTVSPAPGIRHGELRWVDVPPVVSIPHHLRLRHLLHRARLNFRDPPVQVAREWQAGRLLQHGRRIVKVRIASRVGPGLRHDHGVVVTDWRRHGRVRWPQTSHGRPDLRHARVPGAPLLHDRHPPRQPALLEGTEDEDNWDFGQTTAMLLLGLAYLEFASKAVKYRKWTVQWKKNKDNLIPFLQQNSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAJ1</accession>
    <name>A0ABR1XAJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000356</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674444.1">
        <property type="nucleotide sequence ID" value="XM_066804671.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037731"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF200">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="462"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="530"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="52"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8093671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="564" mass="60887" checksum="550707C5F455CC15" modified="2025-10-08" version="1">MQKIKSAICRVPDSDTTAVEVNEAAPAGYSHDHEKGIMEPKTEANVEAGVSAMAAAQAVWGKTGFRLVIIGELDNSTVYTYKNYSTSEFNQLSTLGTLNTAAVIVFVVVKPPIAKISNVIGRGYTLVFTVSCYVLSYILMASAQTIGAYVGGFVLYNIGQSGTNVMTNVILTDLFSPRWRAFAIGFSFFPFLITPWVAALIVGSVVAENGIGWRWGIGMFAILMPFGSSFIIGTLLYYQRKAKKMGVLVSQKMTMHEFCSEIDLGGMLLFVSGLACLLLPLTFAAQLAQGWRTPWIIALLVIGVFILICLGFYEKRVAVYPIIPPSYFKSLTICVSLLILAMDNVGFSATHTYLYSWSVVSYNLDVRTATFLNSTMGVMQCLVGIVTGWWMGRSGRYKWLVVVGACVRLIGYGIMIRLRTQGSTIGELFGQQLIQGAGSGVISTALLVVPTTVVPCAQIPQLLALALCCVFLGSSIGSTIAGGIYTNTMRGSLWKWLSPDASPVMVESLYTSITGELPAWGSPDRTAVNYAYSAVITYITYAAIGASAPGIILALMLPNKELPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAN7</accession>
    <name>A0ABR1XAN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_000374</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674462.1">
        <property type="nucleotide sequence ID" value="XM_066804689.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037749"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016636">
        <property type="entry name" value="3-oxo-5-alpha-steroid_4-DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF43">
        <property type="entry name" value="STEROID 5-ALPHA-REDUCTASE DET2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015596">
        <property type="entry name" value="5_alpha-SR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="106"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8093689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="283" mass="32135" checksum="EA7C06189CB81706" modified="2025-10-08" version="1">MAIIENWLPASRENYDGSPVWMISWYGMGKTSVQSPLNIPGRIAWLTMEVPGFVTLLYIMNTLPAQHGIEDLPWQNKTLAGLFCLHYVYRAVLFPVLQPSMSPIHAVVWSMALVFQFFNATCLGSWLAAYGPTTEAEWNSAAQLGNGGSSVLQFATGLVVFYVGLTSNYFCDEELREIRRAEQRRQERLAHEQGRPVGSIEKHYSVPNNGLFRYMLYPHYFSEWIEWLGFWIAAGVGCAPARCFLVNEIFAMLPRAVSGKKWYIEKFGEDKIKGKYAIIPGVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB75</accession>
    <name>A0ABR1XB75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000596</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674684.1">
        <property type="nucleotide sequence ID" value="XM_066804911.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037971"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="70" mass="7642" checksum="15571F34AC51341B" modified="2025-10-08" version="1">MRALVIVRKRADGTSEVPDTPHIPPLNPATITPFQARSIHDAARNHVGGARFFGVLDILAADRELIMLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBG0</accession>
    <name>A0ABR1XBG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674829.1">
        <property type="nucleotide sequence ID" value="XM_066805056.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038116"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="942"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="976"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1079"/>
            <end position="1118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1130" mass="124977" checksum="FAAC0CC6E1053C10" modified="2025-10-08" version="1">MQRDPSRTSSLKGGYRRDGITSWTATGECESQPWYGRAKETAGDLDFPHAFPEKLIPSTYIVLLWAEQGRTMSLLCCCRSRKVPPSSPRASTPEPELPARPAQAKPSAVPYSGIPTGVRAAATANHSEAPSRIRTPMKQSTVDLSSLEVEESDDGHDGAGLGSAKNSSTSTLEVLKARFIRRLSQLSERNSGSRHTPCSEGELARRAELKRLRQKRIEEELKDEQEAEKKTVPRDCRNSSGQHSGEFPGGGPRDSIEFGVTGPEGAKSDNTSLHDAHKHPLTIDEVIARAIRQRSFSDVGSHKRHSSHEDKSLREYRSLPEMPSSPRLQPVYLPSVYSSNSIASWRLSYSASNLVGSLKQSMESTSNLPTEDPIKEVDSESPSAVTPKPRDHVKTSSSGSDADAEKALELETSERKSSAGSNLTSPATETAATTFDMGKRGSTQSTIGRHSPLDMWLQIQGLELPRCSTSDPSAGMTESGDETKPVDPSSPTQQDQALDTSLPAPDNVDTLWLSVGRREPISHLVAQDRRQIQETTENSSEEDLGIYLQQRRSISSHYTTQSSNPRSPPPLPVMMTPNSVMYRGIYITHPTPDMPQSSGRTTSNEGSDTSSYKTALDEASRLHPVAALNTTSLRRPTDETMSSIQSETESFRQREVELLSVAKRFAGADAGRYQGSHTVSKFREEFDTPQSQNQRFFRSSIFQRCPSRSGRNVKRQFPRTKTATTGTVWRPPLTPAKLPPLDQTPHWFPVTPSNKRQRAVRLEADRREVLRRDREKFHASSHTDLSTEERLQSTPVDRPLYPKVEAKGMSSASEVYLPLRQSKPPPKSWARWPSHTRAARNGPAQQHDSIRPKDFAVDRVASAGPKDRTGSLSGKFGKAIQRSIARIMPNNDGNLSATPNFAAESARRGEPGGYLEYPELELLPMAGGYKELEALERQINHIKRPSENQPTPRPSPNRSPRIPLGQRLADDVHRFQHGGRAGTPEANEHPMTLSLPKLATPTGMHRTAPRVVSEVTTHYETPKSHLSYEDCVPKHMLDDDEGSSKSDSSVNVRRSKSNIEHRNPAQVKYGTWNGRSGRSKAEPVLRKSTHEFGVELEELLDRERDKALDVGVKREDAKSPGGSRPTTIYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBG3</accession>
    <name>A0ABR1XBG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674701.1">
        <property type="nucleotide sequence ID" value="XM_066804928.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037988"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF7">
        <property type="entry name" value="SERINE HYDROLASE FSH DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="260" mass="29216" checksum="9D55D2A59276BF1E" modified="2025-10-08" version="1">MRVLCLHGRGSNTEIFRMQTAAIRSFLEPEYHFEFVEGRWPHLEGNWSVHTTDFSKSKLYGYYNGLDISDILATENELREIIAEHGPFDGILGYSQGGTLAAQLVIRYITENPFATIPELPLKFAIFINGATPPCEEAYDCALAEFAEAAHLFRVFKPNDADNVTRLRPAKLCSGRKVVTDGVHYMTRYGPEWDGRVISIPTLHVRGRGDHSDYGEGLLELCEPGLAEDVLHIYGHDFPRGLEMSRTIAQLIRKTAARAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCE4</accession>
    <name>A0ABR1XCE4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675143.1">
        <property type="nucleotide sequence ID" value="XM_066805370.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038430"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021840">
        <property type="entry name" value="DUF3433"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11915">
        <property type="entry name" value="DUF3433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="464"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="527"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="557"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="626" mass="68840" checksum="811EF5D98C9E5985" modified="2025-10-08" version="1">MTSTSTETTTNPIGAVFTQERITTLDVVMKVVSQSTIIYTDWTETDDFMTWLATTLTDAAGNPTATKSSLVNMAPFLTTYTDAEGRPTRTGTAWHQNQWRVTTKTNGHGGYTTETYATRLTTSTLSDAWGRATSTSTGIVTETLAVTTLYDSNGVPTMTKTMWEPVTSTSTAVVTSTLASNSSRNSFTSANISGLKVSSKDYFVGLVLPPFLAVAISIPVRMLDQTAKLYQPFHALTKKYGAEIVDSLCLQSSSLLGFVTGVQSLMRHHILLSVTGLLLLINAVLIPLSAEAFRFPDSGQYRHRAAQRHDALAIVAAITLRKWKTGVWKNPWSMEVMGLLATNGEFRALMKRLKPKNSGVITNKDAIKAFGQRRFGLKEWYDTYGWEYGVLIKNDAGNLLKGNKKHVGFSNGNMANRSKAMPFYVLSLWGRLLALLLLVALLVVSLVYISTGADSKFDHFMDGGFVWSSVLVLRRWCGCFPILGYFLQCPYRLYRKHYDDIAAVLTPPTNAYSGLWEVCRWRRPDGYLGLVAFTAILSDVLPILLANVPSKVLQASATHLVCTWFAAAILSQMLVVITWSFLVDWPPMSMDPSTVAGAMYFALDPGTFMGGYLTRSSTPGGRSSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDC5</accession>
    <name>A0ABR1XDC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-directed RNA polymerase II subunit RPB3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_001258</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675346.1">
        <property type="nucleotide sequence ID" value="XM_066805573.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038633"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07031">
        <property type="entry name" value="RNAP_II_RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="5">
        <location>
            <begin position="26"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="281"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8094573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="328" mass="35801" checksum="1DA667EA113E8ACE" modified="2025-10-08" version="1">MEYDTMMMDNESLGPSVKISEADSIHVNFELNNVDLSFANSLRRIIQAEVATVAIDLVNFAANSSVLADEFIAHRLGLIPLDSRGADQMLYSRDCDCDQSCGKCSITLTLHASCTSDEVMKVYARDLLVGADRPNVHVGNPVITDPDGLGPLICKLRKGQELNIQCVAKKGIAKEHAKWSPCSAVGFEYDPHNKLHHLDLWYEKDALKEWPKSKYADEEEPAQEGEPFDYDAVPARFYYEVEGVGSIDPDAIVQSGIKEIQTKLASLIHGLTGNDGMNDIYDGPRSPDADMDGGAGWQTSYGNAPDQGWGGGTTYGGQTSYGADQNGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE24</accession>
    <name>A0ABR1XE24_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675590.1">
        <property type="nucleotide sequence ID" value="XM_066805817.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038877"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="188" mass="21153" checksum="2C216D11759B296F" modified="2025-10-08" version="1">MEWSPVPDFSFASALAVLLTLGMIEKTKETDLRFTLLLFAFNLFALKIALTVIFQAYWPPEEIKLNWSKVWAMLGDLTALMARSRFLQLNAEPNSGYMVVAGSEKQIKALGLLMVNAMKGYENGPAFVDFIDIEPSQEWIKAVEDFLSPRPTNHKELMFACLDYLNPDNIDCLDSTFSLTPSLFPGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE38</accession>
    <name>A0ABR1XE38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675733.1">
        <property type="nucleotide sequence ID" value="XM_066805960.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039020"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="333" mass="38760" checksum="B18C1A9079956401" modified="2025-10-08" version="1">MMKDFLQLLSRHFPGSIPAGILFLRGERLKLPGFGWAPATWASGYSEDYPYPLSRMEHGTELVPEGLLVRYPGIMLHCEEPKTVMSYAQSKGFDFPVDRELNDWYRVEILFQENRLPTINDILTNRANKKFNYMLAVIISRPQPKERLAEIGLLVEIYDSPWRRHEKQVRPETILYSRVLSRIRISRIGRTSWREPKDQVIGERTRDDQLWCVDDYSSNLTRLKEISNKERRRGDADGKAKGCRTHQMVKSGVSQGQRPQRRPREDPSLFSKWVKRSHEQHVTKNLGRYFELDQPPQEACVILSLQQWTRSASEHVSTLAIISNLAKQVLSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UTI6</accession>
    <name>A0ABR1UTI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660845.1">
        <property type="nucleotide sequence ID" value="XM_066818657.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051717"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="46"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="353" mass="40594" checksum="E193263171ACB51D" modified="2025-10-08" version="1">MQPYRHERLESPDSIRILDLLPARKWDAPVECRIRQTTVEKACDKYEALSYVWGALEGDRPIGCNGRELLITPNCHDAIIHLRRRFRVRTLWIDSICIDQRKTSDSIQERNHQIKQMGMLYQNASRVLIWLGPNNTGLTANTNRLLKLRSHTDRLKLPYKLWNMILCQRWCQSCTEMLQSPEQMAYGDSESLRRAGQRAVTISLYGSAIGSSWWDLMLYPNCSELSPAGVRDSARQHNPALFESSQQSPSDIILGYLESEESKFESLTRDIQWRANKLVNWAFLVTGSGYLGRAYRTCQEGDQLWLLAGAANPVILRQSGSEYRFVAPAFFDGMMDGELWSDNEEELELLILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU91</accession>
    <name>A0ABR1UU91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661097.1">
        <property type="nucleotide sequence ID" value="XM_066818909.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051969"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="107" mass="11770" checksum="FBBD40BD08357C15" modified="2025-10-08" version="1">MRRRRNTTARRTCSYSSGAKPGSEIPDKHKRTTLLRATVHNSAAVAPCLLRHEARLYSEEVGDQDSLVTKIQVESFSRMVPPSLQNGAATTLRLILGPEVAESIVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVV2</accession>
    <name>A0ABR1UVV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2293 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661652.1">
        <property type="nucleotide sequence ID" value="XM_066819464.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052524"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018744">
        <property type="entry name" value="DUF2293"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113:SF2">
        <property type="entry name" value="DUF2293 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10056">
        <property type="entry name" value="DUF2293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2293" evidence="2">
        <location>
            <begin position="100"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8063053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="342" mass="38180" checksum="07F15E3C9662EC54" modified="2025-10-08" version="1">MPSQTASTHEPVVKVTSPLPKGYIFVPKGNVYITANCRRLTQAAKKTVYAVINAKRQSVGIRVPASIHAQVQSDEQASRADRRSAVAKRDASLEKQFRDAIVRQFPQTPAASVPRIVERAMLKGSRRVGRTGKLDIETKAKLAVRAHIRHTHTNYDGMLRAKTHTKDQARDAILSKINDVCKSWGGKVEDHRHGKRPQKKKDGKDTRRGNDKDNGKLKPKAKGEIKGATTKQNSNSSKEGSSSRRKPTVVNSKPPRQVKKQQVRLARQDGSNHGSNSYSPTYNPYNLGSNAQVGNSLRRQQQPIVIDDSDDEVDDDESDEFEWLESDDNDYVNSDSDWTPDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UYC6</accession>
    <name>A0ABR1UYC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-1,2-mannosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_015162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661664.1">
        <property type="nucleotide sequence ID" value="XM_066819476.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052536"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021848">
        <property type="entry name" value="HODM_asu-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11927">
        <property type="entry name" value="HODM_asu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8063065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="480" mass="54240" checksum="3FBAF4F21FB286C6" modified="2025-10-08" version="1">MDLYHVAGPYPTLSIGVLIAVLVGLGLTLLKRRRLSLSPSSPPPTPTYGGKTSYSTKEPYPSSVVFPPSRRAALAQLLPSSKLAKKKESTIETSELRSKQLPTSHAQDLDKPDQYTPTGISTQEIKALGAFPDYSVLAGVPYPKPCPSFDITKAAFRPFRPFRWTYHQTMAVMKMEPDYWLELESNYFRRMAQRQELLKEHGEKIMFWTPGSELASRELMEMVLQFLCHKYPHYFQLEKGNTILRNQLLKTTTDIAALHPLEVLFRNVPEDYAVMCRNEKDGLYYLRSAMICSSVGWNIGLHKNKVLRAIHDNVPQWEEKMAFSVDSPSSAAPGASRTGKPSSRPTGPPRSAFADNESACTIDDLQLRCDWQTLRRLPVSGAVIFNFKAVFNKLTDLKSEPYVPALLHQVVTQGPRDLIGYKMERHVEKIAAEHLDRWAKKQVEDGLVPADWDVGTLEQHPYFPGWKNKMVDDFPACPCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V241</accession>
    <name>A0ABR1V241_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661756.1">
        <property type="nucleotide sequence ID" value="XM_066816064.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049124"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="70" mass="7843" checksum="19943A21161C2B8A" modified="2025-10-08" version="1">MDATHNQAPSADESMNAFSPTFADEELLREPTGSSIYEPDHVVGESGRRYHGYKEGSYLLPNDEVRRKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2S9</accession>
    <name>A0ABR1V2S9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662244.1">
        <property type="nucleotide sequence ID" value="XM_066816552.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049612"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="92" mass="10641" checksum="ED5539C1D3D507E8" modified="2025-10-08" version="1">MARPLLDIGIWSKVPPVARFCEHPDGVGYRAACMHLPTPEFLWAIGIALFVWFLPDMIVLATDAFAFLYLTYHRRRHELPEIRRRAAARLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2V2</accession>
    <name>A0ABR1V2V2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012249</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662255.1">
        <property type="nucleotide sequence ID" value="XM_066816563.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049623"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF20">
        <property type="entry name" value="PRO1A C6 ZINK-FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="587" mass="65097" checksum="1073DDBE5834D9E1" modified="2025-10-08" version="1">MDGGEREKQMAQEFKQMVKDQATKRRERKWAQMEDASALPTTVADRHSPPKQASVDVDHSLAYGMANLMDMDSGEDYRQYAPGSGSDRSSMTPATSVSDVANHMDQQPSKDRKVAYSRSSGRTNQSDSDDDHDEDEADRELNQAMLYIDYVFPFLSPFYRPQLSESGRGWLLVLLMKNKALFHTALSLASYFTAVVMAGWDPGRHEDCKAHNWSELQKQQGLGIQALQRDLERVNERGVARSLKSSVRCLESIVQALYFEVAVANTQNWQVHLDGASVLFGQIIQTHATDGEKPWFSVLASMSPGNLAKDLGNGRHPWAPSQAAFRFMTASLIWNDVIASTALERAPSLQQFHAELLEGPNPALQTEEFVGCPNWIVLLISEIATLDAWKKGMKASGLLCIIELVQRASIIEQRLQSGITELYHAPIDYPTNRADQLAGEAFAALGVEALHDFDKLRTTPSHSLSAKIWAQAALIYLRVVVSGLQPCQPEIRASVADIISLFRALPSPLCLRTLVWPYAVAGCLATPDEELFFRELVDAMGSLQIFGAVKEALSVMSTVWEHRACTNPDTWDIAACFKVLGHTSLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2Z7</accession>
    <name>A0ABR1V2Z7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_012294</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662300.1">
        <property type="nucleotide sequence ID" value="XM_066816608.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049668"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="8"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8065547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="482" mass="54038" checksum="80FA87CF644A9FDF" modified="2025-10-08" version="1">MRRTLRRSCEACAKSKLSCDLRTPQCSRCLKRKATCSYANEPLSSPPDGQSPESPQDSPTRGGHDWAVTHEVPVLAVRNETPESPISEQLIVSLPTSITSLDPFDSFPRTRLPRQHVQRLIYHFLSKIAFQYYPLDLNADSNPFIVSWWPVALEDPALFHVSLQTASLDDELVAQKGFPISEMLMADSLSLVRQKVENPTSAIEDATMDSVVTLAAIEHGKGNFQISKLHITGIIRMVKMRGGINELKLASPLTARMVAWVCLIVTGSPQFPVQDDDGCGDGLSPIPQWRSTPIEPEPLSIQAPDLEPQIHSILARLNQVVRESQTSGLSTTDLHDLTCYVIHRLLLSPCHTDQYSQSTTVSECIRHAMILYMFIIHGPTYFPHTVMMNGITVQLKNGLEILFATGRKYDEVLLWLVSVGLVASVDTAEHQWFRTRAAESTLVLGLYTWEDVLAQMRIVLWLDKPLGSSFRRRWEEILFNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V372</accession>
    <name>A0ABR1V372_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycogenin glucosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662391.1">
        <property type="nucleotide sequence ID" value="XM_066816699.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049759"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="480"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="783" mass="86603" checksum="E2C355D400E7F414" modified="2025-10-08" version="1">MAAQGGAEEDVYLTLLMNDTYLPGALVLGHSLRDGGTSKKLGALVTLDTVAAEAITQLKASFRNANKHGMYDYIIPVPRIKNPKPSNLSLMNRTDLHSAFTKINLWKQTSFRKIVYLDADIVAYRAPDELFDIAQPFSAAPDIGWPDLFNTGVMVLKPNPGDYYALMAMAERGISFDGADQGLLNMHFKNNCNRISFSYNVTPSAHYQYVPAYRHFQSSINMVHFIGSDKPWFQGRYATTGSGVFDEMTGRWWAVYDRHYRAETPESDPSRPSVLFVQYLTKGEYQPRQLQGLENAPTTSEPNSDQSQHEEPAAAQPPEHDLHFSSSTFDSTSKEPEAEARKEHGEDKAPPPPPSHSQNGTLNDTKPEAANFPATIYEMSRDTAPFVPPERYPSPPRNMYYEVPKERPARHYVKPKAIFPWEINQEPPTRVFAEDAFHKEAGSPIEPTSEPPASSSSEEQQTPAETCVTETSPTRPSHEPATPTTPTISVTSSDPWSSFTRTNAWDEVPEIERYVGTLQKHRRSLSLKSPGIIGIPSRSGEALESERAQRGLKLTDFPSEAERPSLPVTPAPIRRPKFWGGGGGPGVHDDDDDDDDETLLPAAEGVPEQSDWVCVHGRRYEPADCLCDLANVLRYHKDPAAQLQKLAKQQSEMLLQKLGSSGGGGGRRDSSDMPPRPVPFGSEELTSPTYVPQTARVLSPQPVKGHSTSSMVRGIVSEEQAIPEPLRPSHLLHNHLLSYPNQATLVLEQVSRKARTYIITKQLSPKRGRAGCTTDLKAASSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3H7</accession>
    <name>A0ABR1V3H7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662497.1">
        <property type="nucleotide sequence ID" value="XM_066816805.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049865"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="7597" checksum="4F112F47A20C4233" modified="2025-10-08" version="1">MTGLDLACDCMAPLCIQPDLFARCDVTSRVGEMETDAMGFAMEGKEEEGEAARALLWATGPRGRNVTEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V468</accession>
    <name>A0ABR1V468_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin conjugating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662748.1">
        <property type="nucleotide sequence ID" value="XM_066817056.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050116"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="256" mass="27203" checksum="2E8B7285C835DC8E" modified="2025-10-08" version="1">MSAASLFGFAVDLHRRFEEDRLPELRGRSTGEAADGQPTTLAVSTPLLLVGALICLPVISFLCYTLGDLVPVLAIVEDTSRSRGGYVHLPLESTSEAAPGSNAGAQGIATEDMGDTRYRPVSASIRSTLGLLWSIAGFPSLFRGFGCFLALNMANITIQLVIAAIPLVPAFVADVLAPLLTLPVHVAWTHIVVSAPSSRPFWHHLPGFANSFRATALPAAIFLAATAISRRAPFLVFHLLGVTTPKSPLLLNLRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5U7</accession>
    <name>A0ABR1V5U7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663340.1">
        <property type="nucleotide sequence ID" value="XM_066817648.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050708"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="248" mass="26283" checksum="DCDE6B8AFB5E93DA" modified="2025-10-08" version="1">MGEFAAVLTHAVGNAMIAACNPSTVPGIINNGYSNLKSHLPVQSGFAHLIRATNFPNHSTANGPPNTSPTTHPSKHITHAIMSQKALIDPGDLPLGTSAVTVLSFDFLEAIEQFKRTLPADYLRDSWFCALKKQCATAVSQPPSQDTSTAMMFLNGLYRLVCGDVAPESGWAKMTCMISTLCNGPEDDSFDGRQLFLKAANKENEIELLGTIAYGLNADEDSPTSITTAVRVAAQAGATVVKGEAADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6A7</accession>
    <name>A0ABR1V6A7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mechanosensitive ion channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_013484</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663490.1">
        <property type="nucleotide sequence ID" value="XM_066817798.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050858"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016688">
        <property type="entry name" value="MscS-like_plants/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF15">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017209">
        <property type="entry name" value="Memb_At2g17000_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="504"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="447"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="718"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="779"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="730"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="792"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8066737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="829" mass="93307" checksum="FE4FBE6997D793C4" modified="2025-10-08" version="1">MASRQSFDMGPPHLHHQSSFELAETSSQNHNHNASVDPDEHHQHDTSSNTLYRAPTASDVMSESDRETQQDRETQDRRDHAARLKDDLTLLGIERKISNQEELNKSQSRRSDRSEIIKEDVFNAPTNVNNLPNALPATEDEEPSKIFNALKRIKKLPRAARYIFYLLPIFLILLIPVFLGIFLPQEEQPVIGGEGGVQLLWFGIWLEIVWLTLWAARICTAILPFLVRFGAKILGSGNPKKWKAMGEQMELHTALFLWMLAVLISFKPIVNNHKVAAPEPDRFPHITWIEIVQKVIIALFVLAALNFVEKAIIQWIANTFHKRTYMIRIETNKQYIAYLVHLFQYSGDRLATEESVSGYNASGTKTPLRQFQQTVGKTFNKVGDVANRVAGDFTGREVRLSNHPRKVVSELLRNSSSAQVLARRLFRTYAKDGADVLTPDDLSPAFPTEEDAEAAFSIFDRDLNGDVSLEELEAFCDEVHREKKAITASLKDLDSVIKKLDQTFLTIVVIITVIVFISIISASASAALASAGTAVLGLAWVLQATAQEFLQSIIFVFVKHPFDVGDRITVYGNTGATGTGDDYYVTEISLLYTEFKKMEGHIVQAPNSVLNTLFILNHRRSGSLADVFKLRMAFGTPKEMIEELQARMTEFVSANRRDYTGKIITELTTIEDTYAIALNFITFHKSSFQNELIRLTRHNKFALELSKQTAAIGIQQPRRQLQIAGEDSPTDSYGQQSVDHSKLTATRRQRSNSSRFSNNNDMDFYQDVFAARKQTPEAVASASGANLEKTASKASRAGSSRGGLFHRTMTLRQSMDRHSNRSNDRHDMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V6G9</accession>
    <name>A0ABR1V6G9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013537</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663543.1">
        <property type="nucleotide sequence ID" value="XM_066817851.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050911"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047167915" evidence="3">
        <location>
            <begin position="20"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8066790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="209" mass="21697" checksum="64392D682B59B149" modified="2025-10-08" version="1">MKSIFVAGLLMATSVFSAAVPVAAAPQKRQLESQGAILDNLYQQIVVQTTQINATRDNAPENPSALEIPAIADDINTRFAAITEALKQASTKSESQRKTARTIVARQNGTDSGSDDGEEDGGDKCDAACITGKVLDIVQEVASTIRAVIEKFGLAPFLLRINPLLLALSALVIGLDVLVSGLLLTVTAVVNVILGGLGLSLLALGFAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V772</accession>
    <name>A0ABR1V772_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663798.1">
        <property type="nucleotide sequence ID" value="XM_066818106.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051166"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="34650" checksum="EC8D0F4014077795" modified="2025-10-08" version="1">MASSEVDQKFLGKLARAVEPNNALLASMLFKILGLSINLAQQLVKARKQRRLDTTRPTQSLELYFHIIWLSREGLVMLEQYVLPMVGDYVELKVLAYKLRASFYHIFVLFHNHPSVSTMTPEALAAAATMAGMGPSRLDKGKGIARDDISETARSSLQPTHPMEGGPVHPPPGFGHPIPEAVASFLLPSVDYLPTAHQYFREAVALADSLLWGSHSLRLSVRTEYAAFLYECVHDAEGSRQFAKDTIAEVYQASEGMDDDMFNDACELVTVLGKMMKRGLGSSNPSRSRGQSPATVATSQNDSVATAIPAAGMENPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7P9</accession>
    <name>A0ABR1V7P9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Estradiol 17 beta-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_013963</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663969.1">
        <property type="nucleotide sequence ID" value="XM_066818277.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051337"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF236">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8067216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="345" mass="37406" checksum="351F537088B5F373" modified="2025-10-08" version="1">MVASYHQRHGTEQELLLDAILPPKPHFTDNDIPKSLSGKVYVVTGANCGTGKELARVLYSKGAKVYITCRTPEKSQEAMTDIRGGAGPAEQKSGGELVPLQMDLADLPTVRSAAQAFLASESQLHGLFNNAGVMVGDHSGNTAQGHEEALGVNCIGPFLFTQLLTPALATAAKAQSAGTVRVVWVSGFGLEQCAPEGRGVDLDNLDYHDPKPGIERYGISKAGVWLLAVEYSRRHHAADGIVSVAINPGNVRTELARHQGIALKLIAGAIVYPIIRGVYTQLFAVFSNDISTRFDYTKEWVIPFGRIAPLRPDLIKATRPTEEGGNGNAQQFWEWNKDKVQEYMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V8Z6</accession>
    <name>A0ABR1V8Z6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleotidyl transferase AbiEii/AbiGii toxin family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_013185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663191.1">
        <property type="nucleotide sequence ID" value="XM_066817499.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050559"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8066438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="24590" checksum="83D534D6DEF6C275" modified="2025-10-08" version="1">MPRMKTELTSEDIDVALHALDAMFGESPLLMSVAPIRFMVVGGTMAVKYFQVRSMTKDVDYLTDPNIDSDKMYRAEIRTAVQRVANQLDMEEDWFNDEVKLWIHAPKRLGLFLESVEQNIVIFQGVNMTIYAARLDWQLERKLRRITNGKQTAQSNKDVSDAVAILSYLKGDGPPLRAADLEAMNFNGFEGSMSKGVRKVREEYRKRFEEDGIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH34</accession>
    <name>A0ABR1VH34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UBX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664260.1">
        <property type="nucleotide sequence ID" value="XM_066814970.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048030"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UAS" evidence="2">
        <location>
            <begin position="179"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="525" mass="58080" checksum="2D2AA9882623A0BF" modified="2025-10-08" version="1">MAADDDTVDIAQLTPDQQAALEQFTAFTAQEVKDAVPLLERSQWNVQIAIAKFFDGEGPDPLAEAIAAQDSIPSPAAARHENLQESLLAASSPFQPARANRPDPAPRISTHRPPFLLSLLLTPFTLGLRAVSTFFRTFAYILAFLPAQIRPRAITASVTSGWKGTMGRRMLLPRDTAARFKREFEEEYGTPDGATGLPFVESGFAQALDAAKKDLKFLLIVLMSPEHDDTESFTRDTLLAPEVKDFINEPSNNILLWGGNVLDSETYQVAAEYNATKFPFSCLVCLTPKEGSTRMSIVKRLVGPVSSSTFLAEIQTAINKYSPDLATARAERTAQEFARNMRAEQDSAYERSLARDRERARQKKEAEAAARAAEKRALEQAAAAERNSALREQWRKWRATTIAPEPDAAVKDAVRLALKMPEASGNGRVVRRFAAATTVEELYAFVECYDLLQQEDGEKDGAGEKPSEDEYEHEYAFRIAGLMPRIVYEPKDTATLGERIGRGGNLIVEDLVPEVDDEDEDDDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHP2</accession>
    <name>A0ABR1VHP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664542.1">
        <property type="nucleotide sequence ID" value="XM_066815252.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048312"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="111" mass="13222" checksum="A18C2CF72FDA3A6F" modified="2025-10-08" version="1">MCEKFEEQEFAPAQKDSFPESSDSVYQFTPRPMDLVPLISRHEFYRRFYTCFETSKRYHLHHTCKVLRGHSHDVLDRLPKRTLELEPGGDKRETFWGLYAQDAVSLQRVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHR9</accession>
    <name>A0ABR1VHR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_010989</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664594.1">
        <property type="nucleotide sequence ID" value="XM_066815304.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048364"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="160"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="5">
        <location>
            <begin position="515"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="59"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8070786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="653" mass="72798" checksum="1795D2797769FE8D" modified="2025-10-08" version="1">MEEASTLMPEKKGQPAERQPPSRPQDQQRQRFTVPNYVWQAIIAMELLRHTAAAHPRHRVSAASLNRTIPSASSPARARASPALDDPNPDTSWAKLFDPNPDHWNWGNRTASSTSASERNSDPYAGRGIYMCGYLDVPLDYTNKSDPRIARGWPKKTERTIVINPGGPGGSGTEYAWRAAEDITERLSGGRYDVLGWDPRGVNTSQPAVSCFPHDADRDRWALAMLKHRVAAVSNKMQLDLMDAFNAARFRACWERHGDLGRFVSTAFVARDVEEIRKALGEEELTGFMVSYGTGIGQTYANMFPNSVGRLILDGTEYVRDHRLAGGFGWTALDNVTDAWHDGFLGECLKAGPEHCALAKGAEGKSLTLFELDVWVRDILGDLISYPLPAYTEKSGASLVMYSEVVAAIYQSLYNPHSWKALAQMLYELGHGNTTLAGEFLEALWEYDPTLPCATTSKKPSSEELTLMVVCSDAYDDKERSLEWWNNQWKIMTKQSWIAGDSRFFVFACQHYTTYWPKPAEVYRGDLNNTLKNPVLLVAETYDPATPLRNGRRLLGEMGENARLIAHHGYGHSSGRDRSACTDAHLKTYILDGTLPEDQETDCYADEKPYLYGVKREGGEAGSLAAVAVASGFDPVASWREHVRETRLLGPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIA6</accession>
    <name>A0ABR1VIA6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011169</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664774.1">
        <property type="nucleotide sequence ID" value="XM_066815484.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048544"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR PBCR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="541"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="564"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8070966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="725" mass="79083" checksum="2AA2E3F23E3AF434" modified="2025-10-08" version="1">MDDRVSARAKLPSRACESCRAAKIRCQPSDQAGICKGKWTVLNSKEGYGESTYAVIRCCDFKKECIFRARPRTRRPRAAEGETPLPPPSGPSQTFSIDFNLPVEAELGSSFDDLLEKHDQFVEDLVPSAAEDGFDNDSTMLSASSSGGGATFSSISSPGSSMGASSSISLTTLGIKPQFNLNSAQKLLDGFQDMLSFCPLVALPEGANVKSMASQSPFILLAILAATSCSSSLQGFNLYDDEFRKVLGLKFVTSGERSLELLQGLLVYNAWYPYHLRPNDRRTFQYLRMAVDIVHDLGLDDEATFAAQLESDVGPEDLERLRTFISCFYLVSVGLRSWGKPSTLPHSSWIATCCDLLEKWSNSQQDHVLIWLCRLQSIADGMGELRAGYSRDTNGQNNHQNNLVHRGLEAQLREWQARMPDNVSAMPTVKMASLSADMQVAACPLMTPHRPKAERAGGMPLDPVKLMGAAHTWCAFLDLVVALTPSELDRFSAVEWGHLIVAVILVLKLAFPVDTCPLFDAAHARNTLQFGAYLEKLCADPPPENDVDKPRTATGRGAARGKSRNGSQDTMTTSKNNGNAERSGNNITAAFRIILRKVKAKFDRRVAAAEAKVAAEETRAMRGCPFFDGSLTDYIPLWEGQTSIGNYSSLSGSSSSSSQLQLDGNGNIIGMLGMDGTAVQQPSSFRLDTPVFHDLWATMTQGWAADDSLPNLTMDTNDAEDFGHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ45</accession>
    <name>A0ABR1VJ45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665071.1">
        <property type="nucleotide sequence ID" value="XM_066815781.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048841"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="2">
        <location>
            <begin position="33"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="431" mass="46176" checksum="09D3FE9B33BAEE08" modified="2025-10-08" version="1">MKANLLVSAGVASAAIPTVHMPLNLKYGAGKKVSTELKLPYSDGTIEVCYDLGSSDFWMFRPNAIQNWGKNCLLCQGLCNVTVPDAGIYDPSKSTSASEVAPWDAMYGYGGGVAKAYRANGVVNDTFTFSNDAGYSTTVPDVEVAMTFYLQQRILDPKGECNPVPEYDYSIMGMSPYYTSPDRNIENTTGPHFRHHLLEQGLVENTVQSLWFEKAPAKLEDTYTGSGLQGGIDLSKFSGPLVKIPTLPATDIAYGAVGYYTLQPNVTFVAEDGAGVDIPVDRSDTVTIPECIIDSGATRDGLAPSTRTASSTPARPNPGQELAWPAPCDTIPTDGERAFLRYSFAALDPAAAPIEISMPLRAYARQQDPEDAALGWCTMSLYLGTCMLGSPFSTRAFFAADDARLELALAKGGVAERGSGVDPAHVVDRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJ52</accession>
    <name>A0ABR1VJ52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_011469</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665074.1">
        <property type="nucleotide sequence ID" value="XM_066815784.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048844"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045083155" description="FAD-binding domain-containing protein" evidence="7">
        <location>
            <begin position="22"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="7"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8071266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="145" mass="15791" checksum="5416511F1086B3B7" modified="2025-10-08" version="1">MSQPGFKIVIVGFSVTGLTLAHCLDKLGVEYIILEKRSAIVLKGGTSVAIMPNGGRILDQLGLYDAFENDTVPLDLTDTYLPDHMNVSRTSPRFTSTKPSPTPNRVVLAPELTPMMEGDMAVGADGIHSKTLREMWRVMGEPVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJG0</accession>
    <name>A0ABR1VJG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monocarboxylate transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665085.1">
        <property type="nucleotide sequence ID" value="XM_066815795.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048855"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="335" mass="36997" checksum="C803AE339713AD11" modified="2025-10-08" version="1">MPLVQQRLQRWRRPMVWAGCACLSVCLGTFLLYFIARMFMREGERYIPPAYIGDANSTVLNESICTTGLARGSFATAFEVPYPYLRALWMVRASSWFYYPILGMVNEYWTSRAAAWRTAHCAVVHQGLSGRRYAPFVLQALLAPYGYQTTAARRRHRALLVCPRPSAPNVQIKGWAIVDQSPRLWGLLRRQPSSGAWSTSSRPCTHRHPHHPSSLGLDNRTAGALLLALMSVSQAVSQFIFGLLPVVAGTIAAGPLVCFAIVYSFFGADFTALWVRMNSAIADDGTAAPGAFSLLNFGKGFWDVLARPVGEVLVGRLSPTTSRGRYLMDGLSCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJQ3</accession>
    <name>A0ABR1VJQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cupin 2 conserved barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665284.1">
        <property type="nucleotide sequence ID" value="XM_066815994.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049054"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02231">
        <property type="entry name" value="cupin_BLL6423-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047142">
        <property type="entry name" value="OryJ/VirC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156:SF2">
        <property type="entry name" value="CUPIN TYPE-2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156">
        <property type="entry name" value="SLR2101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="24809" checksum="B14F69FCE829B255" modified="2025-10-08" version="1">MAAKEERNRAEGYVTTSHPIQGLPRVVRHITGVNPEGQSVFLSTDTGDHHRELVKKSGLANILYTTREHPVDLNGDADIKYARENEPGITVKGGTVCRMIDFGPGAASPMHRVNSLDYAVVIEGSFKLVLDSGEERLMHRGDVTIQRSTSHQWINVTGGGFLPARVLFVLIDVKDLNVAGAKVDGFLGELGKDYVGLPGHEGAKGNGTNGTHDANGTNGAMVNDYMESEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJU9</accession>
    <name>A0ABR1VJU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664960.1">
        <property type="nucleotide sequence ID" value="XM_066815670.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048730"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="472"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="587"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="77"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="422"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="587"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="693" mass="77157" checksum="7F2867099BB9855A" modified="2025-10-08" version="1">MADPLHPTTNLPAGAGRLDVLNTSQPDREIPPMRCCCGDLECSVLRHNSTVLDSVEKDVHLAASVGQALLERHEAYMADAKRDRLELTSRIEQLEMDNRELEAKNAHYIESNRDLLDQLETLNSTITRSHAALFPASHPPTRGETLRAESLERELEYLEQEQADLQSNLAATHEEARSAMSRWKRAERGIVNLQDQLERMENEAKMERERHAEMMGRMEKQCEVEKELNTAAGRLKEPPPSGLSVLRIDNSNLQQGIVELREMLMNSNDEIQSLRDQMVCHQPMESHQPMDSEDVDVPQTLRAELESQESAKTHTSMVSQELHIHHHYHVPPGVKQEKKPRKKRQGLTPGIFIPPTQSSGTATPPSVWRPTQVTRTQRDSNRPHRWSIQSEQPSEFALSSAPSSPTSNHRNSLFDPIMIESLPTSPTTSVDPMSPKWRSHHKNPSNVSMRSFQVPTNFSLDATQPSQTHTIYEEGDDGQELPRPMVSTDKYGIEDESRSKYGDPYSDENTDDARSIRNRVHRAMSHESILSLSGGLDIHTLKSRPSQMTLRPISSVTSVTASCCVVARPMLSRDTAKRSSLVLRDNYASSPSTSSLRAVSGPLPASQRSGPSKLGKWAGSWMPWGGGAASTSVSSTTATPTKAEPESSGDLQHKTFRPPARCEPGGCHPRFPCVLERSPETHAEQGATRSGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VKC6</accession>
    <name>A0ABR1VKC6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010888</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664493.1">
        <property type="nucleotide sequence ID" value="XM_066815203.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048263"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8070685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="118" mass="12832" checksum="4998841593B0EA5F" modified="2025-10-08" version="1">MSSIKFDPLADVFEGALKQPASSRKGFQARIRARGYLSLFWSDIWLAGLVVGSCLALQKLNDEVSPAKGLSIFLPEGTLAEIENITKTAFDLPKPLYKILQKPIVDFLAGPTCLFGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTE0</accession>
    <name>A0ABR1VTE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amine oxidase</fullName>
            <ecNumber evidence="7">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_009161</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="7">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="7">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665438.1">
        <property type="nucleotide sequence ID" value="XM_066813476.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046536"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF91">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0186">Copper</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="9">
        <location>
            <begin position="259"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="672"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="672"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="686"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="724"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8074498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="754" mass="83382" checksum="091B5749FCFE4E96" modified="2025-10-08" version="1">MASVSSSARPHPLQRLNDEEILKAKDILAKSHDSGENLLFRFTYLEEPKREDMVKYLAAEHQDDKTATLPTLPRMVKFVYDVIKGPGDHTLADAVVDIDSGKVVHTQTHPRESQAGYAPFEFAQFQETCINSDMFKEALKEFELPPNFTITIDPWPYGGQDPDEDIPRYMQGLVFARDASKDNPDANHYGYPLPLIPVMDFNKKELVRIDRLATGGKGDPLEPAAASSETPKKLFANAKSAEYVPELLDRPLRTDAKPINITQPDGASFAVADDASLVTWQKWRFRLGFSPREGAVLHDLCYDGRPVFYRLSFSEMCVPYGDPRPPWHRKQAFDFGDGGAGRSANNLGLGCDCLGAIRYFDVWDTDPEGLPTLSKNVVCLHEQDAGVGWKHTNFRTGRAVVTRLRELVVQFIITLANYEYIFAYKLDNAGNVTLETRATGIVSVVAIDEGKTSAYGNVNHQHIFAARLDPAIDSYDAGETAVVLEESHSMPAIDPLTNPYGNGYEVRRTPLEKAAFADAEPRLNRVVRFENRTRKNAVSGKNVGYKLTPSATQLMLAHPDSTQAKRAPFAQHHLWVTGHRDGELWAAGEFTNQSRGEVGGVKAMVERGDWFGKEGEATNGDVGEGTEGEGKLSTPVAWVVWGLTHNPRVEDWPVMPVEIHQVHIRPADFFTSNPALDVPSTKNETSVLVPSSSSPCCDAKEQKKTDASQQEDPVSHMQGSGPDVKPKDIGSGSKEGKDKKRFTTLLSGVFGKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTL1</accession>
    <name>A0ABR1VTL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Estradiol 17 beta-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009257</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665534.1">
        <property type="nucleotide sequence ID" value="XM_066813572.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046632"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF236">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="212"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="349" mass="37368" checksum="BF8C118BDDBDF859" modified="2025-10-08" version="1">MPPTFSSGFTQCFPPAPAFAEKDVPGLTGKVYIVTGATSGIGREIARILYSRNATVYLAGREESDTIQHIKKAEPRSAGVLVFLPLDLSDLRSVKTAAKRFLAAETRLHVLFNNAGVMTADDGPGGMERTAQGYEMQLGVNCLGPFLFTKLLMPTLLATAADKSGGITHTHTHDVRVVFVSSFGAEMFHEPGIGIDLDNLDYHNDPQNRACTAMASAKSASGRTGSSSPSGSPPPPPTRGREEGEGEGVLGVPVNPGNLRSGLFARQGLLLRLQVALLHYPAVQGAYTELFAAFSPEVTPGTAGYVVPFGRLRPICEELRRAARPEEEGGADLARRFWEWSEEQVAPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTP9</accession>
    <name>A0ABR1VTP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acyl-coenzyme A diphosphatase SCS3</fullName>
            <ecNumber evidence="8">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">FIT family protein SCS3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SCS3</name>
        <name evidence="8" type="synonym">FIT2B</name>
        <name evidence="11" type="ORF">PG997_009298</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65568"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57368"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:156554"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(9Z)-octadecenoyl-CoA + H2O = S-(9Z-octadecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65564"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:156553"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:50044"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:132023"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>hexadecanoyl-CoA + H2O = S-hexadecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:50032"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:132018"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665575.1">
        <property type="nucleotide sequence ID" value="XM_066813613.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046673"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03231">
        <property type="entry name" value="SCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019388">
        <property type="entry name" value="FIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046400">
        <property type="entry name" value="SCS3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129:SF0">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10261">
        <property type="entry name" value="FIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="306"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8074635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="338" mass="36555" checksum="7833278D051020B6" modified="2025-10-08" version="1">MADTNTSSLRSRSDKMAATSNGPESSASQSTSAAKRNPPHIPTALETLALILYPTVLAFGTLFSVLSPETRAAPYDSTRQSHVQDLAPSYFARKDNLLNVLFVKRGWAWITIAFAAFVVTHPALTSSTTRTARAGLRWAAITGWWFLVTQWCFGPALIDRGFRLTGGQCAIAESNVIQGDKHTGARDFATAVACKAAGGRWSGGHDISGHVFLLVLGSWFLLQEVGWVAVRVGALAGRRDERTVVMGDGAVKGAGVEAEKIEGQGETTDAHRTLGLGGRFALIVVGLCLWMLLMTAIYFHTWFEKFTGLMTAFVGIYPVYILPRWIPALREIVGLPGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VTS2</accession>
    <name>A0ABR1VTS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_009260</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665537.1">
        <property type="nucleotide sequence ID" value="XM_066813575.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046635"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03467">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21496">
        <property type="entry name" value="FERREDOXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21496:SF0">
        <property type="entry name" value="RIESKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="7">
        <location>
            <begin position="62"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8074597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="184" mass="20296" checksum="47096A7570B42D36" modified="2025-10-08" version="1">MATTLPFAFGNRRGDPWNFVGLASSFPNLDLDGKAVSERRPCNPEGPKAPGCKVYRVPRNTPGVTEASEVDAGVPDTTTLKDQVLVFQYKGKFHAVDNRCPHSSYPLSRGSPFDIEDFGIKLSAGISCPKHDWSFDLHTGQGDRGAYKLAIWEIDLRPVAKSSTEGQGQTDDQEVWVRRKQKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUQ4</accession>
    <name>A0ABR1VUQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Kinetochore Sim4 complex subunit FTA2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_009643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665920.1">
        <property type="nucleotide sequence ID" value="XM_066813958.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047018"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025213">
        <property type="entry name" value="Sim4_Fta2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13095">
        <property type="entry name" value="FTA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8074980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="262" mass="29739" checksum="EC2FE8BB0C6D6689" modified="2025-10-08" version="1">MGKTKSHKIGNDLLPRCEGPKLHAFECENAAIAWGRRLDEDRGDSSTTQSAVFEVTIESRVYALKVFKFYDPYSDAYYWGPLLRDDIPLEEILCYTDPFFAECPVKCHGYLYLSKDDEAFLTELGVDLGIDILDDSLRKALGHGGRVRAIVKDMAPESSGVTARSLTKVLRRVRALNQLDVFNRDIRLENFRGGLLVDFGSSWTKPHIVLDALGAVDKRDSLLEDLVMFDDMVAEEDIKTRLKALPNLEYCEKLRPRTDKAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVM4</accession>
    <name>A0ABR1VVM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTPase-activator protein for Ras-like GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009935</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666212.1">
        <property type="nucleotide sequence ID" value="XM_066814250.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047310"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21206">
        <property type="entry name" value="CH_IQGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05127">
        <property type="entry name" value="RasGAP_IQGAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF14">
        <property type="entry name" value="CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="4">
        <location>
            <begin position="330"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GAP" evidence="3">
        <location>
            <begin position="1112"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="109"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="825"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8075272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1748" mass="199668" checksum="C382C630C1E8E7BD" modified="2025-10-08" version="1">MSHRPHPLRQSYTVDYANLDSVNGVNRNPSTTSSSASSGYSYTSDSYDFGRASTNSSISSVFGPTVRTHKRGMSEVPARQTTSRMTRANTFDEPKANVQDIYNMARQSLRPLPQTPPGAVPSPAPAPSPPSHRTTPTRTTPTPTQTSPTKTPTPPRHSSHSHERGKTIDMGRLSISTGISNGISTGISNGRTSPVIPNGRISPTPLAHPSTARIGTARPTSMVLTRSDSIRPGPMVSHSHSPSVPQSPLAAPDLAQLGRSSTSQLRTLSTLGAAEEFAIAAPTQEVTGLRGRRRLQRVGNAGSRPGDNYGFGGRNWMDKQRQFLQAYEYLCHIGEAKEWIEDIIHQQIPPIVELEEALRDGVTLAEVVEALNPDRKFRIFRHQRLQARHWDNVATFFRYLDQVELPDLFRFELIDLYEKKNIPKVIYCIHALSWLLFRKGIVDFRIGNLVGQLEFEHHELEAMQKGLDKLGISMPSFGNMGADFGVEPEPEPEPEETEEERIDRELAENEEMIIDFQAQMRGALLRLRLGEIMNSLWDSEDWIIDLQSRIRGDWTRQVMEYRLQMKRFSVQLQSAARGYLVRSNLMSRENFWKSKEKNIIKLQSAIRAMNVRHEVQDTRSQLLAAEGPIRSIQAVFKGYLAREKLHVQRQETESSEEPVKGLQSAIRGMLLRGRVEADLHELHGQEPAIGRLQAAAKAMMLRGRMEADMHQLQLQGPAIGQLQAAAKAMMLRGRVEADLHELHGQEPAISRLQAAAKAMMLRGRVEADLHELRGQEPAISRLQAAVRAMLTRDQVSQQRVALEQFVPQWEALQSISRGRKIRSDVETTKSELREHEAEIGSLQSQIRAAAVRREISEKLEALNAEEPAIHEALLAELQSHEEEITSLQALARAMLCRAQLGDLLAELDEHEESVSELQAIAKGFIVRINFEEKRKHFNENMSKVIKIQSFVRGKLQGEAYKSLTTGKNPHDFDFNEEIEFERMRKTVVQQVRQNEMLEQYIDQLDIKIALLVKNKITLDEVVRHQSNFGGHTSNLLANSNMASANQFDLKALNKSSRKKLESYQQLFFNLQTQPQYLARLFKRVREQGTAEKECKRIEHLMMGLFGYAQKRREEYYLLKLMSRSIREEVESCATIQDYLRGNFFWSKLLNNYTRSPRDRKYLRDLLGPLIRDNIIEDPALDLESDPMQIYRSAINNEELRTGRPSRRPLDIPRDLAIKDPETRELFIDHLRDLREICDQFLNALEDFLPRMPYGLRFICLQTFEALCQHFKREPQHQVLQLVSNWVWRFYLQPAVINPEQVGVIEKSLSPLQKRNLSEVAKVLSQIASGRPFGGDNIYLQPLNAFVSDAAERLAQITSDLISVRDAESTFDIDEFNDLYAKNRPTLYIKMTDIFAIHSLVAAELPAICPNRDDILREIMQDLGSAKHNENEMLAAGSSDIQMFLTPKLHDVEDPDAEAKALFMETKRCILYIIRVQTGANLLEILVRPPSEEDERKWAQVLRDDFNNGSNTKGAYSDANMIDVTRMSYFDMKRNALENIMRLEQLGRISKQNYYQDVLNAIALDIRTKSRRRIQRQRELEGVRLTLGNLHEKAKYLEQQRKSYDDYIEQAMATLQKHKGKKRFLLPFTKQYNHQRELERSGRVPKFGSYKYSVRQLFEKGVVVSWQGVPERDWGVINLTISCDEVGIFSLEGSRGHIQIPGASAQVPIEDLLQAQFEAHQFMNQFEGNLRLNVNLLLHLLYKKFYRTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVN1</accession>
    <name>A0ABR1VVN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666192.1">
        <property type="nucleotide sequence ID" value="XM_066814230.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047290"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="492" mass="54314" checksum="C922D9F6F0126CE3" modified="2025-10-08" version="1">MSTTLNAAAAVFNPQLSASLHNDICRRGWAGLAPDLNFEESTTTWWDTHGSECNATVASRLAPQLIQFLKQARIVRPDLHDQARSNFFFYLRGLASPNSLIPDWPVVDPEEPDASRYVILYHVTLLMSHPVGLVIDQHTLKGQVMQSLTIDDTIVEQSQRPWVPLQDILAAYLNMIDMGKITSEENPANKVDYTALDASERAAIIAGTWKPKVGPYESPWLLNPHSQAILDRSVAALENLLEAIEKRMPSSRAEPVSEVPLGTPVAEGAMGMASVAEKLISTNQASEHSFIVKFLRQVDGLLASARPDLRFVAPAVRGAGRRAAVPPILLFRGELRDGTTAVTTFPGGAWNPFASPYKERTAPFPSGLWIAEHKVDNPNYDNACRLLLPDRVVLAPPGRTTQHYAKTTDGFLLEQPGAKGEGLSAGLYQTSCNVFVGRHEVLLFHVLEHWVRRVEDGTWAVDEHGVAGGMEKWVEADESEAMAEKYRLPYTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVZ7</accession>
    <name>A0ABR1VVZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sulfatase-modifying factor enzyme-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666370.1">
        <property type="nucleotide sequence ID" value="XM_066814408.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047468"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="entry name" value="paralog of FGE (formylglycine-generating enzyme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051128">
        <property type="entry name" value="EgtD_Methyltrsf_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397:SF2">
        <property type="entry name" value="HISTIDINE-SPECIFIC METHYLTRANSFERASE SAM-DEPENDENT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase-modifying factor enzyme-like" evidence="2">
        <location>
            <begin position="226"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="495" mass="54968" checksum="3A485D3D51DE1818" modified="2025-10-08" version="1">MASKPNPYAFPLEVSNYVSAPVPSMGEWEIMWKAWDLVTTQMIPADALMEQPIPLRNPLQVLRGPHTNIASFPPLMATGKPLTEPAAYAKYFERGIDPDMDNPAQCHDHSELPAVWPELSEMLEYREKVKRRIKLQYDTGRAYSDRTIGRALWIGYEHEGLHLETFLYMAILSPNIRPPPGMPCPDFAGMARDAFSRRVENQWFRIPEQELTIGYEDPESDEGPDRYFAWDNEREPYDVKTSAFEAQARPVSVGEFAAFLVDTGKTDAIPAMWVKLRNTQDGETTTSRLSSTESDVNGHAEDHTKNQNGDPGGDTALQVFIAQHGIRTVWGPIPYPKRVGGARLPTLHEVRSIHEHAARLKESQQPPTTTATESQSPFSDPPINSQNKTMHTDPGSIFVDLSGANAGLQNFHPVPITHRADHLCGLGDLGGAWEWTSTVFAPQPGFKPMDIYPGYSGPAFVRVGVVGTDFMDGKHMAITGGSWALPPRIAGRKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWD1</accession>
    <name>A0ABR1VWD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_010216</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666493.1">
        <property type="nucleotide sequence ID" value="XM_066814531.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047591"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF5">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8075553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="33160" checksum="D18A7CB6EBB77B3E" modified="2025-10-08" version="1">MELCRLLPKCIVKFVGPWLMARSGAMQTVGRYVTKLVHERLVARDNDNDGKFLDCTQFIIKESRTDRQRSPIRLVQQMVALQFASAHQLPMALAWAIIMLCKHSEYIPLLRHELQQSELHSRKYQTKDLLLLDSFLRESSRLNPLDCLSVQRKAIQPFTFSTGEHIPAGNLVAVPQQAIMRDENNYCDPETFDPFRFYTTDLSTTEPVVKFTDSHCWKYPFWGSPSHSCPGRWYAADTMKHAIVHLLKNYDMELATSGPPKVMKWTTALAPSFGNRITLRARPDSDLCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWF4</accession>
    <name>A0ABR1VWF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_010226</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666503.1">
        <property type="nucleotide sequence ID" value="XM_066814541.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047601"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="567"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="593"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="675"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="745"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="821"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="849"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8075563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="921" mass="102575" checksum="3548D9DBB93499EA" modified="2025-10-08" version="1">MEDDEKAAVHKGGEKDDVISSVPAAPNSTAQEKIKNEKETKEEPEIAQIVHAIEEGQPVTTDQHQRVAAHYGRKAEADHLAPSSDVEYILDQIVGMSEADAVEILVGAIARHADDPNFPATSLARMRLLVAGPKAYCSGSVGDVGAGAGTLSEGRVGETATAAAAAAAIPTEDDYAFDLKTEAAIYHHHSPYPEVRSVTRPGDDPSTPVETIRAYLLGLAFMAGITAVNTFFSPRQPAIDISAVVMQLLVAPCGLFLARVLPDWGVTVGGRATRSTRAPGASRSRLPQYLGNTWVTFSYEIVLALSVNFFGMGFAGLLRRFVIYPISCLFPEVFPALALNRALVEREPASKRNEKIHGWTISRYRFFLACAVLMFVYFWIPNTLFKALRSFNWMTWIAPQNFTLAMVTGFWGGMGYNPLATFAQQYFARFVSGLIIIGMYWGNMYWSAYMPINSNEVFANNGKKYNVTRILDKQSNNINMDAYREYGPPFFSGANVFGQGGWFAWYPLTLFSVSIQHWEALQRSGAEMWRGLLQFRQQRGSKGKSVYDSYDDPFSRLMRAYPEVPDWWFLGVLFISLALGIVALEVWPVHVPWWSLFAVAGVSAVMLVPATLLRASANVKMDFNVLFQLLGGLWFPGNPEALIIVTAFGQNFDEQASDYITGQKMGHYAKIPPRAVFRGQMLAVLINTFVFVGMLDWMVVNFNDGTLCQWNNAQHFVCTNAVLVYASAIEYGAFGVRNMFELYPILPWCFLMGGAVGIAWGLARRYGPAIHAWARRRTSSEGRFAAYERFFFKPVSYLWYFDPAVALKGALNWTGGNNLSYATNAMYISFIMMYYVKRHYGAWWEKYNYLIEAGFGAGIALSAIIQTFSFAFTDTEIPPWWGNEVTTAGVDYLAYNQNASLLAVPAQGYFGPPPDQYPMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWZ7</accession>
    <name>A0ABR1VWZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009082</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665359.1">
        <property type="nucleotide sequence ID" value="XM_066813397.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046457"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF48">
        <property type="entry name" value="PROTEIN VAPYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="345"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="380"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8074419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="493" mass="54506" checksum="4FD3C37EAB2AD684" modified="2025-10-08" version="1">MELLSLPGEILHLILVQAALSRGLKRTLRLRLVCKTFDKAIYYPALFESRLLDNEHLRRRHCRGPVYTCNTHDHGVAKLWHNYLVHRAMSERDASVGRFVEIRQLAQTIVDEAQAQMSETEWDLRHVVDVLCWSALESGTKAPGGPYENWKREEATDLDKLQGFPTPMPRLSLLAAAAVFDMVPLATALLAEGHSPKHHNNLLPPAIQVAAQSGNIAMLKLFLTHPSYGSGFDPYAVYGAAVRGDMEIMKLVFPSPNGNDGANDSGYGSINWRSDASKAIPKARRATLSPEVYEYLSNAWAPGPRSGRTPWYADLVSHAGRGNAGMVTYLLDERGVPVDEKNSEELESALERACRCGQDEVVDLLLERGADPDFTGHALWGAVPIRMAASGGHASIVRKLIEHGARLEAHSDGGRDAEMVDLLLERGATIRAGVSLATTVSHLGYGSMLDIVRQHGFDADPATYGLPIRWIEWPENTRLKAGWFRRKREGEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VX60</accession>
    <name>A0ABR1VX60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_010090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666367.1">
        <property type="nucleotide sequence ID" value="XM_066814405.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047465"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8075427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="15101" checksum="86FDAAA544F0B223" modified="2025-10-08" version="1">MSEYTSTREGFQRAMEWSLTGRSEDTAQYVEDTTLPTFYQVMNGKRIAYDDYVKGIAEWRGKISEYKPVVHEFLRDGDQLAARMTGTIKVEGAATDFESFMFAKVDKETGKLEWLVERSVWGPAGEAPEHGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W061</accession>
    <name>A0ABR1W061_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666438.1">
        <property type="nucleotide sequence ID" value="XM_066814476.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047536"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046105672" evidence="1">
        <location>
            <begin position="21"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="428" mass="48693" checksum="9CF831C2B2211A10" modified="2025-10-08" version="1">MARIWPHVTLFLVFIQPILATASASDVQPQVQEWSVVKSVPLVVRDYVRLIHDFSVCHGYSNGDSDNNLHYSRPLEGLVEIVDVLMGRTVPQILGVMEIIDKTGGIPLKRDPEENNKSWYVLKRLAEISARLRTLVVDETVYGRATKFGDELTDRFHKRFAFLNDTLSDHGRELVRLTLESYEGDFVSGHVFATQLERKQDWVAKEAAWNLLEFLNAIVVPYSQLDVCLQRPESEECGGVTLPLLLALLEDELIPFLRTVHGVAWTQTSPHRHKKYRDTFPGWFMHAMTSVLDFERSGVGRAHAELETAIFKLQRLADALRPHQRESAAHLVERYHALQHAGAQAIQKGIEELELHTVYMDQKLTQEHLRKDSLPLDPKQEPGRGPRFVFFSPNTLSSMQMALSESADMLANWSSPARWNRASEDGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7T6</accession>
    <name>A0ABR1W7T6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007364</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667021.1">
        <property type="nucleotide sequence ID" value="XM_066811679.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044739"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="59"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8079546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="529" mass="58728" checksum="B1F516A76C135D5E" modified="2025-10-08" version="1">MGSTTQEAQLLQDVKTVAVVGAGISGVASAAHLLRYGFEVTVFERSSIAGGVWHYDPRTANEPPYPNEHPPAPHNPDSSEAPGEENAPRKTSFDEASVVHAPPGPCYVGLRNNVPTSLMRSTLLDWPEGSEDFVSQDHLEKYVQRLAEHTGAQEKTLYDTSVESVYKDPGSPQWTVHTRTLVRLVPGENEFEFVDRTWQFDAAVVASGHYNEPRVPNIPGLLDLKRRFPDRVMHSKRYRTPEIFRDKTVFILGAGVSSLDIARESEGIVKHIYQSSRGGKFDLPPSLLPSSAQRVAGIQRFVELEEKTPDSTSLSEDSLIPFEIVLDDGTRLRDVDHVVLSTGYISSYPFLGPQLQAPGVPLEQADGRVVITADGCVTHNLHKDVFYMADPTLAFVGVPYHISTFSLFDFQAEVVARVFAGRAALPVESEMRREYAERRVKMMGGGGSKEFHSLYGREIGYIDEVLGWVNRDAALLGYEGMKGWMIGGVVSGSSLRRRWRFGGGLLLLRVRMRSTRVVMLAWTSSLRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W805</accession>
    <name>A0ABR1W805_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major histocompatibility complex- class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007437</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667094.1">
        <property type="nucleotide sequence ID" value="XM_066811752.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044812"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950">
        <property type="entry name" value="ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950:SF16">
        <property type="entry name" value="ZINC TRANSPORTER ZIP13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047128446" evidence="6">
        <location>
            <begin position="26"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8079619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="411" mass="42887" checksum="BD4A2322A45E26EE" modified="2025-10-08" version="1">MGFLHRNSWFLLLLLIGIVSASVDAKLKADHASTGALSIEALEEKLQLCPVVADLNAEKLAAASTTSTLTSRIFAVLFPGSPATNALLATLYISGPPNFLLALCPTNIDPSSLSVMVAFAVGGLMGDTLFHLLPEIFLGEDSPEHVRFVMVEPNRNLLLGVAIMVGFMTFVAMDKGLRIATGGAGHEHGSGAHSHGEVAPSAAVVATGIEDAKDSVKSRKKSKKDVFKPEAEPVKEINPSVKLGGYLNLIADFTHNITDGLAMSASFYASPTIGATTTVAVFFHEIPHEVGDFALLVQSGFSKRAAMGAQFVTAVGALLGTLIGIAVQEYGGGGSGGAPIGMTEGIWGTSLSWGDMLLPFTAGTFLYVGTVAVIPELLETGPDKSAELRKTLVQFAAIAVGAGIMLYISWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W8J8</accession>
    <name>A0ABR1W8J8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_007190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666847.1">
        <property type="nucleotide sequence ID" value="XM_066811505.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044565"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF13">
        <property type="entry name" value="MFS GENERAL SUBSTRATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="361"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8079372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="59354" checksum="60B09FF6523F97F9" modified="2025-10-08" version="1">MTAADERSPLLPEAKRNKTRNNAVSRLWSRVWSTPNRVVFAGFLITLSFSVTQVPLFYMFHIMECDVFYSKHPPFDGPGDRCSRNEIAAGTATQFSILGMSTTFCGTLNLFFSGWLVKRYGPRLALMLQTTIPAVRVLLQILGVQAGGEAGIMIIQTTQLVTVFGGPAGYILVVNTIAGEVVEPLQRTALFGRLQGMIMLGMSLGLWVGGMIGDRYGIQSPFLTAFCLFCCASVYARLALPYISPESLTDGKKSDTKGVSGFLAPLRVLAPQRLQLHSGQIRKHYGVFFLCCGIFLGVVATGYAPILIQMYATAEFGFTQADNGYLMAGNALMRAFFLIVIFPRIIAAGRKWFARSATKNMTTQCDPETPGDIPTDPRQFEAPSAGQSEEEPVALAEITDPVIEKLASQFDLLFLRWSLVVDGLLTAVTAFATQGWHVYIAAFILPFGSGSAPAAKGVITEMCPKSQRADALNAVTLVENIARLATLGLFGFVFAALSEIGKSYLTFFCNAAIAVLGMGVLLFSHFPPNESTLVEEEHEGEDGETAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA24</accession>
    <name>A0ABR1WA24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine protease</fullName>
            <ecNumber evidence="6">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_008145</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="6"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667802.1">
        <property type="nucleotide sequence ID" value="XM_066812460.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045520"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050966">
        <property type="entry name" value="Glutamyl_endopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008256">
        <property type="entry name" value="Peptidase_S1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462:SF8">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00839">
        <property type="entry name" value="V8PROTEASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="77"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="47"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="202"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="289" mass="31553" checksum="60EAF4A4A85AACD5" modified="2025-10-08" version="1">MPTNGRPGLTSMHPILPNPNKPDRRLANIPPPNVVTISEAHLMSLYNITAPPPPSGSRPAAAQQQQKKRETIGPDDRVRWDDTNYPYSAMGRLTGPTFLCSASLIGPRHVATARHCHFPEIPYYFAPAYNGGEVLPGAQVTTVLMPAEPFPEGACGEPYDWAIFILDKPLGEQLGYLGANSIDDSKRGKPIFYNYGYPGDKDSGSRPYRQQSITVSTEKRCDATGPLDTDADTSQGQSGGPLWLEEDGNIWQYGVFSLLWWVNGVYAMASFASGDGFVAGVVHARETWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAT4</accession>
    <name>A0ABR1WAT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Vacuolar protein sorting-associated protein 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008414</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the retromer complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668071.1">
        <property type="nucleotide sequence ID" value="XM_066812729.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045789"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06891">
        <property type="entry name" value="PX_Vps17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014461">
        <property type="entry name" value="Retromer_complex_Vps17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053055">
        <property type="entry name" value="VPS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037907">
        <property type="entry name" value="Vps17_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011791">
        <property type="entry name" value="Vps17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="183"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Sorting nexin/Vps5-like C-terminal" evidence="4">
        <location>
            <begin position="314"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="508"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="550"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR011791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="613" mass="66983" checksum="4E378D551394B2DC" modified="2025-10-08" version="1">MDYRSTMADEENPAGSSPWGSSPPASPRRNEPANYSSLGNEATYGGYGSQDPSNGLQHDDLTKNAFARPNTASSTASTHEYNSPQQGDGSHQPEAGGPSEQEEHGDDAGAAQATGEEQSQPQGEPGAPVGQGQQQQQQGRKPAYPQYKLQAKITGLERTGRKDPIMRFDVHTNIPRFRTTQFRDVRRLHSEFVKLADHLISANPEALVPAVPPALTSAGAGTDEDEIRVKALLQRWLNYVCSNEVLMRDEEMVLFVESDFGYSPMVKRKQPATGVRRKLLKQFAPPPDDTPELSDARPIVKLFYLGSMDAGHKVDKLVKARRGLGLAESDYGVKLGGMNVQEPHQGLASAYRKLGKVVQTVGDCHAAQATAEATTIGDPFQYHSQDAFIVKETLTNRQLLIREFLQAQESTRSKLNAADRLKASSNVRRDKVDEAITALDDARNNEFELMRKTTRVTQNLVHEKRKWFTRTATDLRLSIREFVLREIEAERRTLALLESVRPDIRAIDNSGGLSRLGREAHPTVRRASMAASQGPKGDAWSGVPRRTDNLSRSVSGSIMTSNVAEGEEEGEDAAGAAGKAPSSGTRGLSGLAEDDEDRVDARNAASRLATSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB56</accession>
    <name>A0ABR1WB56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP synthase regulation protein NCA2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008470</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668127.1">
        <property type="nucleotide sequence ID" value="XM_066812785.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045845"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013946">
        <property type="entry name" value="NCA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234:SF1">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08637">
        <property type="entry name" value="NCA2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="534"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="595"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="631" mass="71319" checksum="C6ACAC8F54532793" modified="2025-10-08" version="1">MTVVSDQVRRLDAQLDRIPFTGAAEFTATHHASAEPSRVKDLLRIIKFLSSSANASTAAQPILPTWQVKSLLAQSQLLSEPSDEITQYETDLEWLLVSKATVQTYGIIMRTLLDQIVPLSDHIWYWDTVLSSPASSSLYMVQTSPMRLWGWSQEIYQDSKARLRRNTGQVTGLFAEEHESTWGSYMSQNWQRFYGIVRESIRERSLADIQRRAKSPFTLAQEEARQRQSRLKKLREMTASGLGVLIDEGLAFGGNGSDDGKSDIIMSNSQEWKGVVERSVALMDMVLKDVLNLDSGVADFEDRVFAGVDEDPELSIQVEDDDSNRPSVIAKRLHYLLEDQLPLHLKSAEFLVGAHGRPSRLVRYWLPATVLLFSSSTVLRILLNRQKEILDWVADLGVTVKDFWFNWIVEPTRKVIGTIRHDSNSDIAIMSRDSLKSDRDSLERMVVDFALDRPTSATGASSLSESQVADIRAKVQQGDLTPVLRAYEKDLRTPLMGAVRGDLVRTLLIQVQKTKVDVEVAMTGIDTLLRSQELVFGFVGLTPGILVSIAVFQYMHNATPSPNNLLSYKDHGLLVCELHVLRRLAFDLLPTDAYKQRFLEDLEELGNNLKGIRSQLRALDRIRWVYSKWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB63</accession>
    <name>A0ABR1WB63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Polyketide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_007247</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666904.1">
        <property type="nucleotide sequence ID" value="XM_066811562.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044622"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF40">
        <property type="entry name" value="NORSOLORINIC ACID SYNTHASE STCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="371"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="1311"/>
            <end position="1623"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1675"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1797"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="702"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1311"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1468"/>
            <end position="1623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1637"/>
            <end position="1671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1760"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1894"/>
            <end position="1916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1658"/>
            <end position="1669"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="1343"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8079429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2292" mass="248207" checksum="9C62A46027FF73AC" modified="2025-10-08" version="1">MGSHRTNPMTLYLFGDQTFDVEPHIGVLLQEKDDLFLQTFLRGSYNAIRLEIYKLPPAVRGTLPRFSCLEDLASWRQNGTGERCIALDMAMTTLWQLGIFILQGDGCFGKTQSSIVAGLCTGNFAAAAVSCSRSRTDLIATAVDAVVASFRTGIVVADVAQRVTISRDGKSSWSFVVEGTSSASLIQNFNDQSTLPSISRPYISAYLPNAMSISGPPNTLARLMNSDDFKPLTKKDLPIFGPYHAAHLYSPDDPTAIVSGLRGGDGAAKSENIPFLSTKKTSTETRYFSSLLREAVVEVLMRPLQWSALQESLESILRAASPHRFSIVPIGSAAHQLFSKALRETEFGSLLAPTTRPPTNGTATTRCSPKKPRLAIVGMSGRFPDAKNNEAFWDILRQGLDVHKTVPPQRWDAGTHVDTSANPRKNTSATPFGCWLQDPEQFDARFFNISPKEAAQIDPAQRLALMTAYEAIEGAGIVSDATPSSRPDRIGVFYGVTSNDWMETNSAQDIDAHMIPGGNRAFIPGRINYFFKFSGPSYAVDTACSSSLAAIHLACNALWCGDVDTAVAGGTNVVTNPDFTAGLDRGHFLSRTGNCKTFDDGADGYCRGEGVATVVLKRLDDALAENDPVLGVILGAATNHSAESESITRPHVGAQRTIFRKLLNETGVDPYSVSYIEMHGTGTQAGDAAEMTSVLDVFAPHPAAPLQGKGKGGGSSSRRARGGEERLYLGSAKANIGHGEAASGASGLIKVLMMMEKNLIVPHCGIKTKINHNFPTDLEERQVRIALEPTAWQKRGEHGARRVLVNNFSAAGGNTALLLEDAPCRRPEVDAAAIIDSRKLYPVAVSAKVGASLQGNLRSLLAHLEQTPEVSLGELSYTTTSRRTHHPHRTLFVGSTVGEICDKIKTVIHDGVGMTRPMGSPRVIFSFTGQGAQYPGMARQLLQESSVFAGELRRLDQIATSLGFPSLIPFVDHDEKDKDAPAFSPCVVQLASVCVQMALVKLWASWDILPAAVVGHSLGEYAALNAAGVLSDVDAVFLVGTRARLLEEKCTAGTHAMLVVYGPVDRISEALRGSESESGYETACINSPTETVLAGPRDEMPKLQETLKTAGMSSTLLQVPFAFHSSQVDVILSEFQTRAQGVTFSSPKIPVIRPLDGTISDATTITDPEYLVRHSREAVNMLRALTAAQEAGLVTDRSTFLEIGSHPAICKMVKSTLGSSAAAVASLQRGARPWDVLARSLKTLYDGGANIRWAAYQQDFPRAHKVVPMPSYAWDLKPYWIQYVHDWSLRKGEPAIQQSSAGPRIESTTIHSIVSESGDSKRVQIVVEADIARKDLSPLVQGHEVDGIPLCTPSVYADMALTLGAYLRGRYQPNQTEKVIDVSDMTISKALILNEQSNKQLLQLHAEADWATQSVTMKFMSFKKKTQELQEHARCIVRFKPPTLQPDLQQSRVAEVQARIQALREGVVSGATARYSRAMVYRAIRPLARFHDDYRAIDGILLDSGTLEAACRLSFGGVRQSKGDAFHTHPAVLDALTQVCGFAMNCNDGTDLDVEVFMNHGWGSLQLFEPVRFDGRYTTYTRMEPGPDKLWRGDVLVFDRRRGRLVAHLGQIAIQGVPRRVLKVILSLESGRKGQHVAAAAAPRSGNVEKSKTPEKISSSPAAHSESVSRPTPKQIELALIDVGIQIIAEESGVAVEGFTDDTVFSDMGIDSLLGMTISARFQDQLDVDLDFNGLFFEYPTVKDLKAFLAKSLPVAGPGTSAVDGYTTPDADSSADGSKTPKTPETPKALENGHGSNADFTRALQIIAEESGVEAAELGDDTCLADCGVDSLLSLIITSRFRDELDLAVENESLFLEQPTVGDLKRALFGAPENGVKAAMPVPPPPVVDPEVEAQPLVNGGSNHGKKTNGTQQGPNDEVRLALLDSRKQAVDQLVETFTEGFSAPTSDNNGPVPAANQSVVLVTGGTGSLGSNLVYHLAQLDTVKTVVCLNRRNREADPATRQFKAMREKGIRFPDALKLKLLILQTDSALPRLGLEPAQYDALAASVTHLVHQAWPMSATRALPGFASEFRVMRNLIDFARDAASATSRPAGFRFSFEMVSSIGVVGLYGQQQQEQHDGGKAPLPVVFVPETSATIDSVLPNGYSEAKWGCERMLEATLHRHPARFRTMTARLGQIAGSKTSGYWNPMEHFGFLVKSSCTLGALPDVEGKLYWTPVNDVAATLADLPWPETTQFLQTALRIPRLVPFPDWLARVRQAPQRGNPALILSEFLESNYLRMSCGGGWSWTSLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WCD1</accession>
    <name>A0ABR1WCD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable electron transfer flavoprotein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007606</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </cofactor>
        <text evidence="6">Binds 1 AMP per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="6">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667263.1">
        <property type="nucleotide sequence ID" value="XM_066811921.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044981"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000049">
        <property type="entry name" value="ET-Flavoprotein_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294:SF8">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01065">
        <property type="entry name" value="ETF_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="7">
        <location>
            <begin position="26"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="257" mass="27856" checksum="C164F9565693E94A" modified="2025-10-08" version="1">MSALRILVPVKRVIDYAVKPRVNKAQTAVETAGVKHSMNPFDELSVEESVRIREKKRYPPGVEDICVVSAGPPKSQDILRTAMAMGADRAVHVEAKEGDEMEPLAVAKMLRALVDKEKSNLVILGKQSIDDDAAQTGPMLAGLLGWPQATQASEVKFEGDSILVTKEVDGGVETVKAKLPMIITTDLRINEPRYASLPNIMKAKKKPLVKMSLSDLGVANERRLKVVKVTEPAPRQGGGKVEDVDGMVSKLKELGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WLH0</accession>
    <name>A0ABR1WLH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_005629</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668867.1">
        <property type="nucleotide sequence ID" value="XM_066809944.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043004"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="4">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="3">
        <location>
            <begin position="126"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8084358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="409" mass="43101" checksum="C87BF35CB5BF7713" modified="2025-10-08" version="1">MPLPVLLEHRQSGSPCPGANGGQIGTLRQYNVLCGSRLVGKEIGGQQTASLGDCVDLCNDHAGPRCDGVVYQSNGHCILQAGINKGATTLDAGADSAIAAGMLQKPSSSCAALGSGTIQSANGMNFQITCKKVMSGNDFEVQFQMSFEDCMRACAKDGRCGGVSFEASQSFGFKNCYLKTPFSATSNQLLDQPSIDTARLTMRQRGNGNGNGNQNNQNNNNNGQANQPPPSPPPPETTMVEVTKTIVTSAPATIAITTTGADLATGGGDATVPGRRQRKTQGSLAPGSSAAGETTDPSEETDVSSMLQIAGPVAGAVAFLGIVGFAIFFFCRRRRRRRRQRQLRGEKGRWADLSDGREDGGSIWRDTTTTATTEVRDSRNGLKLNRVSTHAYGDPGIPHEFEGPHAVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WM48</accession>
    <name>A0ABR1WM48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669078.1">
        <property type="nucleotide sequence ID" value="XM_066810155.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043215"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051727">
        <property type="entry name" value="DnaJ_C3_Co-chaperones"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140:SF2">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="175"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="238"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8084569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="297" mass="32806" checksum="35126D4C746FEE76" modified="2025-10-08" version="1">MAQIKKCLHSDPENKACKKLLKQEKSIEKTLAKVNKALDKNQPMTGVKMLVPQGEDKGLIEEVKEQVKQFKETGIIPEKAQNTLLNRVAELACQAYYDMNAKKASTYCKESLELDENSFYGLLYKAKVQLDADEFEASINLLNQAAEVRPEKKQNIVNPLLQKAQVALKRSKTKDYYKVLGVPHDADERQVKSAYRKLSKIHHPDKAVKAGLTKEEAEKKMANINEAYEVLSNPELRARFDRGDDPNSNEPQGNPFGGGGGGFGGGQPFMFQQGGGGQQFNFKFGSGGGFGGFPFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMF2</accession>
    <name>A0ABR1WMF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Riboflavin kinase</fullName>
            <ecNumber evidence="4">2.7.1.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Flavin mononucleotide kinase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_005991</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>riboflavin + ATP = FMN + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="4"/>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669229.1">
        <property type="nucleotide sequence ID" value="XM_066810306.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043366"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749:SF6">
        <property type="entry name" value="RIBOFLAVIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="10 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Riboflavin kinase" evidence="15">
        <location>
            <begin position="21"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8084720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="202" mass="22034" checksum="1F86EC2F3F185D7E" modified="2025-10-08" version="1">MAETPAASERPRIVCSDNGPEAPYPLQMEGEVISGFGRGSKELGIPTANLPVDESQISWIANITSGVYFGYAALRLPANHPDIPAASSSNGDSSSTKYHIFPMVMSIGYNPFYNNSKRSAEVHILHKFAQDFYGAPMRLLLLGFVREEKNYAGVEALIEDINIDCEVARRSLDRPAWTPREGVVGKGTGSLDGSWLVREDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WMV8</accession>
    <name>A0ABR1WMV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_006078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669316.1">
        <property type="nucleotide sequence ID" value="XM_066810393.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043453"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8084807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="138" mass="11883" checksum="2D4ECC380776E2CC" modified="2025-10-08" version="1">MPPPTTKGTYTAKPTLSPAASATASASASASASASAGGSGGGEGGGGVGTGTYVTVSATAGSGGVTVSVTASAGGTGAGAGGGGGGGGGYGGGTYKTSSPAVAYTSATAPPSVVTAGATSPQAPIGLVAGVAVAMALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WN55</accession>
    <name>A0ABR1WN55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006183</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8084912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669421.1">
        <property type="nucleotide sequence ID" value="XM_066810498.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043558"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20336">
        <property type="entry name" value="Rcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="733"/>
            <end position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8084912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1034" mass="114642" checksum="0435720A77E8F150" modified="2025-10-08" version="1">MGCAKPSVLGQQYQNALKGGREQHPPLHDASPLSDMEQEYDLLILTDATGSMHQYLPALRQALPKIVSVSCLTDAFSRWHNCRNDNNNNNDGDITREGMIAFAKGLRLGGGYDWDEAVKTGAAHAYSVMRPEAITLIMLYADAAPHMRWHDGRNVPLEQENLKADAFGVGSYFVDWVSACRTLSGKTHAPKYAKPVRSQVFSIIDNSRIATVAPFAYLSHATQGSCFWMRQAASSTTIASLTMDILLPWMGAGKQGAAVPESHVATARLIRYLNADDFDHMSDEADERIAKYMPSRSLPNYVDQSKGTIDVVDVQDHSMKQLIQPRATPIPDFSKRYTQDRGYAKLVVDHLRKIIDEDITSITINPVFGSLWRTVCNDRDNPARNELLERFSAAEIEAIIQEVVDEDRFPCVFLDPTQVWTAGTDKTTQGVENEDANMATWTRADLLEIGRSCHPKILRRLGRALTRLSYVSSANEMPEHVRDMPQNELIRIPLALAKAKYQRVFWKALLHLVVPGTKLSGRAAAVLAALSIRMGIRPLLDAADQEMLSWKEKWNNLEVPETWNTNCISLLLDADTSFTERHKRKAEDSVYATLLKPSDRRLFERLVDYSLLKANMDTSLTARVGWHPDKTRAPVGPLVPCNECHFPRSVTIMAPGGICGFCLIPDTHYTRKPKSEALQLNVSKDDDNSTSITWVECCNVDCRAQYVVYDSEGLNVRAKCHFCRRGKTSERAPTVECSKCLSRIIWPDEYRPEDLNVETYECPACVGGYKTIVEAETTSRLLCNQNGTSWLLRNSDSMIKHPLTNESIFKTVSAAAALGDFADKVEVLPQSHKESLKLGGKMARNTEEIKACLLGGSNRAKPSLGPAAYASEISRSKARACGLHVVGPVARKRSALTVTPNAVQESGSWLYAWCVSCGHAKRFAERVCARGAPAELTGWRCDDCQPTVAAASKGETGEIFRECPNCGVATEKTGDCNHMTCVCGAQWCFVCGALGEDSKAVYAHTSQSHGGWYGVDGGDDEFELYDDDSEDEWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNN8</accession>
    <name>A0ABR1WNN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006422</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669660.1">
        <property type="nucleotide sequence ID" value="XM_066810737.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043797"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF57">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="527"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8085151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="561" mass="60202" checksum="55CCD3F65FA19887" modified="2025-10-08" version="1">MILTQYTYIYVIGTCFALLDAYNNGANDVANAWATSVSSRSITYRQAIVFAFIFEVLGAVTVGARTADTIKNGIIPASAFRDDPGVQMLAFTCALAGASIWVMWCSRHSAHVSSTYSLVSAVAGVGVAVAGASQVQWGWNGGKGLGAIFAGLAMAPFISACFGAVMFGLIKFVVHLRRNPVPWAVYSSPLWFLIAGTICTLSIVYKGSPNLQLDKKPPAFIAAVTLGTGFGVCLLSVLFFVPYVHALVIKRDASVRAWMFVQGPLLFKRAAVEPSAQAVAPKYAVHQQQQLVSPVLSLNFGDGDSSEKAAVEVHQTQLTYKEQVARAEARLHARLREGRGPMGWAMRFLHEHPMGEGRIYEDAQHEELRRHWGTPEGRRMDRVYAHAPKYPDEVEHTVLTACTASFAHGANDVGNAVGPWAAIYQAWSTGSASSTKAPVDTWQLAVAALTISLGLATYGYNIMKVMGNKITYHSPSRGCSMEMGAAITILIFSQYSLPVSTSMCITGATVGVGLMNGTTKAVNWQRIALLMVSWIATIPVAGSIAGVIMGVVLNAPHFPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WNV4</accession>
    <name>A0ABR1WNV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_006488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669726.1">
        <property type="nucleotide sequence ID" value="XM_066810803.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043863"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8085217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="161" mass="17049" checksum="0E03433F67FD4010" modified="2025-10-08" version="1">MPPFKAQHDLAAELLKTAKIRDMEAALPIMTRWAPRAALAAGDTLAKVNGGGPNPFEKRMLGPAETILLGAPLPMGPREGASVSSLLTARQVAGQLVGEHTSGSQAICGLCGTRMSRGNRFLGDVGIMAHSHRLGNFHGDPVMRLSGLGEYGQSPWKGRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPM0</accession>
    <name>A0ABR1WPM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_006739</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669977.1">
        <property type="nucleotide sequence ID" value="XM_066811054.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044114"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8085468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="39498" checksum="14DEA05D36D6BD05" modified="2025-10-08" version="1">MIMYKLTWEPICNSQRWYTDSHGSDSVSVPLYQWASDISIDVVCHAFFGPSLQGNRPDVTRAFMQFEDYSWQALYQYPNFLCGSMNKSREKVRGAIEEYFALPDEQRFDRSWLVAQLEGEMKQLDMSPQDISALFFQLYWGINANLRKALFWALSHLLFDTELMESVRHETRPAIKGNGIDMSYLLDPQTCPRLLSLWDETIRMTAYAASVRFLTRDIELGGKTLRKGGWIMIPQRQLHYNTDVFGESASTFVADRFVANPELRKHPSLRPFGGGATLCPGRDYSKHIALAFIAADLNMLEITLDPPTQHFPMGEEGNPSPGIIGVKGGHDLTVRLRPRARTENIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WPT7</accession>
    <name>A0ABR1WPT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_006827</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670065.1">
        <property type="nucleotide sequence ID" value="XM_066811142.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044202"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF1">
        <property type="entry name" value="HYPOTHETICAL O-METHYLTRANSFERASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005739">
        <property type="entry name" value="O-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="236"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8085556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="397" mass="44146" checksum="42AF7CD2893C2F15" modified="2025-10-08" version="1">MSSPSVSALLERIAAAGKAYEHSQEPGSREDLIDLSQSLVAALEIPSEFIQRSFWSEPAKSAHIRLAVDVNLFQHLREAGACGLTPESLSHKTGLDVPLLQRILRHLTATKLVAFQDGKWRGTPLTDGLAEQRYQHSIAFCYDVARPSFNGFPAYFRETGYRQPTSLTDGPFQAAHGTDLPFFDWLVATPPHLSHFDSFMSAYRAGKPDWWDFYPVAEQLVAGFEPGKDGNSDAFLVDVGGGRGHDLVQFARVHGCHPGRLVLQDREPVIATAEKSSRFEAQAHDFFTPQPVRFARAYALHSILHDWGDAEGVKILENLRPALKKGYSRVLFNEIVLSEENPTPAATSMDMMMLAHFAVKERTEREWRAIIESAGLRVVKIYSYPGVAESVIEAELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WQ75</accession>
    <name>A0ABR1WQ75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7726 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_006961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670199.1">
        <property type="nucleotide sequence ID" value="XM_066811276.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044336"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056143">
        <property type="entry name" value="DUF7726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42339">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42339:SF1">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24852">
        <property type="entry name" value="DUF7726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7726" evidence="2">
        <location>
            <begin position="131"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7726" evidence="2">
        <location>
            <begin position="246"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8085690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="393" mass="43004" checksum="BA1095C26A3509EA" modified="2025-10-08" version="1">MSSSGWSWDPARPLGDRDVNVLWPSLMPEAQNSANGNAPNGTNGINGHHHSFSAPPPPQSHLDNGIENEYAGAAQSPNGAKPAASPQSPASDSKPTKTSAPRKRKSDAVVIEEPSPEGLPEIPDDDPRLEEIDQSCNQIRSKIRRFIESGVMKVGEFQNAIDVSAASYRRFMNQTGVHQGEGSDAYLNACRFFKKRELQGLKAVPPKKKARSSIGGKDAGKTDKQKAAEAIDTGDIKLDGEDEGDVPVYETCDELRKKIRAFLKKDGVTQAALCRAISACLPDDQVVQARQLNTFMGKSGPSVGNHSPIFYGGYIFFEKLRIKEDKPKSKFRLEMEDIFGPGRGGRKKSLSHREDGKPGFETKSDLNGPMFMQDNERLSEDKHGQLFLITVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WRF2</accession>
    <name>A0ABR1WRF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_006327</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000005">
        <property type="protein sequence ID" value="KAK8085056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066669565.1">
        <property type="nucleotide sequence ID" value="XM_066810642.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92043702"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052406">
        <property type="entry name" value="Chromatin_Remodeling_Comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003150">
        <property type="entry name" value="DNA-bd_RFX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970:SF14">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51526">
        <property type="entry name" value="RFX_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ARID" evidence="6">
        <location>
            <begin position="20"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="RFX-type winged-helix" evidence="7">
        <location>
            <begin position="626"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8085056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="922" mass="103754" checksum="88AB91A925A5FB01" modified="2025-10-08" version="1">MAPKKGSAADKPYIHEIEPTAEYDEFIKKLEVFHSARGTSFEKCPKLQTMYGHVTVDLLKLYKAVIAKGGYDEMNKIQKAWGALANELGMWFEDNKGMGQLSFQLKQDFYRYLSAYWVKDQFGKDPPPKEILEQQSCATRHGPVATRTLESFNQTVKRSGADTPVKETQAAESTPVSGNRASGRLREAPPQRIPFQPETGPTRASRQASSQHATPNANQGLTTHNSQPPPPHHTPQRHDPNNPLHLIQAQQAALRGAIPLRPVNTPGNNPAEFARRQRQLRAEPPPPARPIAPGAGFDGPNIYTRCLQSLRSGIPSEQAFALNHLVKISFERGDKYKFESFLGLAEGLIEKGLEVGNLFYHVDWQVAYFGTDETEDIGTLDGANGTGDIIERIQKLKPKAILDYMQPADFADQLVRVTEAVLTIRNMLMLQENAYYMRDVYPLKDLLCIILHLPSYEMLVELKHFALDIAEQLTPGMELNSEDPLYRSLLAQLDSTDRGTILTALRAISRISMNLDATNKLQNVPSSVLHNIMNWLLLNDEELMDACLDFLYQYTAVVPNVESLLSAVNMERVVPHLVRLLAHGAKRVKEDLILEPERKDSASEEVAPLPQDLQEKLSSTDEPQRCFHWLQSLFEEDSESHITQIAIWQAYQSSFGGNNRNTLSAADFIRNVSHVYSGARAQIIRGPGEVQRFIIEGIRARTCPLNYETKEEYARCQWVTASNPAIKKCGIFFPTGESMWHHLLTAHLGQAAGEDGKFENRELEVACQWSNCHRYPQPTKVQLSQLTRHLKTHIPLPQKRGLSESTESIAKRQRKSYVVPAKTMCVTWEQTLVTKDERKPQLDQAAGIPLSAVLVLRNIARNVVKTESEEELLKKEEAGGESGGWNERLFRPVMSRLFEVMTENKAMASYIASLLQLVQQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXA3</accession>
    <name>A0ABR1WXA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670662.1">
        <property type="nucleotide sequence ID" value="XM_066807044.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040104"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8087768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="283" mass="32442" checksum="27A8AFBE7B9903EC" modified="2025-10-08" version="1">MAKYINVAHSEHSPNTGPAPSAPRAVRPEHYSRFHLVGFSFYHGDPMKTNQDVHDFLQKPAFMPWRKSRGDVDSFLRFETTLRVLFEAVVFFQQFWGQRGFWRNLRTLLKLDTTISADTIEDAVKLYCECRRSCLSKVVKRGKPPSKIAELADIVNDLRAGEHCPISIPDWEHCEAKWRSKLYYTLCDQGVHSQQVVKGTCAPELHDLSASPRSETQRRDRPEPRQLSPTRRPLSPPPRRPRSPPRGPSLDQPQRPRDDEAIPGAKAGLPPSHRRVRQSRSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXC0</accession>
    <name>A0ABR1WXC0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase-short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670703.1">
        <property type="nucleotide sequence ID" value="XM_066807085.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040145"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF86">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00290)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="212" mass="22932" checksum="F801D7FA40C92141" modified="2025-10-08" version="1">MLYRVVKLRPLFDSQLTLSIPFTGATTGIGEATVAKLAAKVVFGDIKAPEQPPGSDHVTFVHTDVTSYASVLNLFKQAWQLHGRIDYAISNAAVVETGKLFATGNDDSAIEEPPPTLVLDINLKGSVFFTRVAVHFLRKSLARHREATGDAAQKDASILLVGSIASLGEFPGLFQYSATKQGIMGLFRSTKNYLPETEGIRVNAVLPNSTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXE4</accession>
    <name>A0ABR1WXE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxysterol-binding protein-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_002774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8087813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670707.1">
        <property type="nucleotide sequence ID" value="XM_066807089.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040149"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF212">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8087813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="50094" checksum="0B92B8207F226E32" modified="2025-10-08" version="1">MASAPPETINEDIPQNDSGKLRTFIGILRRFIGVADLAAVRFSLPSQLLEPRPNLEYWTYLDVPNAFAAIGTAEEPVDRMLEVLRFWFTKDLKYVKGKPCKPYNSCLGEFFRCTWDAENNAPPINSPSAAAGGNISSASSVKSGKGVISSAASTVSVPPMSENPSGTTRIAYLTEQTSHHPPVSAFYISCPEKGVHARGYDQISAKFTGTTIKVAPGEHNLGIFITLEKRDNETYQLTHPAAHLGGILRGSLSVSVGEAAFVTCPKTKIKVILQYVEDGWLGRAQNKVEGVIFRYDPEKDDKTRIKDVPDKDVLVRLAGNWKEKIVFTHGPKPVDSHPPEKQTVIIDLNPLEMAPKNLPPMDKQAENESLVLWDGVTQAIHSKQFSKATTVKQELEEKQREKAREREKNNVTWQPIYFSQVTDKGGKPELSEKGRQVLERIQKGDWSLEGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WXZ8</accession>
    <name>A0ABR1WXZ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA topoisomerase</fullName>
            <ecNumber evidence="3 7">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_002994</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3 7"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066670927.1">
        <property type="nucleotide sequence ID" value="XM_066807309.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040369"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF21">
        <property type="entry name" value="DNA TOPOISOMERASE 3-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="9">
        <location>
            <begin position="2"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IA-type catalytic" evidence="10">
        <location>
            <begin position="167"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="521"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="536"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8088033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="663" mass="74581" checksum="CF2020D8B4BCDCCB" modified="2025-10-08" version="1">MKILCVAEKPSIAKAVAEHLSGGRSETRNTRNKYIKNYVFDYDFGGQPWGNCTVTMTSVLGHITAVEFPSEYKDWRHPPPERLFDAPVNTVIADDKKDIAQNIETQARYSQGLCIWTDCDREGEHIGHEIREAARKGNAALTVKRARFSNIERAHILHAARHLIMLDDRQVNAVAARIELDLRIGYALTRFLSNNLKSLGGPLANLVISYGSCQFPTLGFVVDRYFRVKNFKPETFWSIKVKHKKDGIDVNFSWSRNRLFDRASVVILYERCLAAKTAVVTKVQEKPTKKWKPLPLTTVELQKMSTRFLRMTGQQAMTAAESLYNKGFISYPRTETDRFDKGMNLRTLVQKQAQDTRWGAFAQNLINGGFQLPRDGRHDDKAHPPIHPITYAGPSAALNEFEKKIYEFVVRRFLACCSEDAKGVATDIDILYGEESFHAHGVIVLERNYLEVYVYEKWTGTAELPKFTLGERFEPHEAMMTEGKTAPPSYLTEADLIALMDANGIGTDATMAEHIQKIQDRDYVRTVPRSGRQGGGDDDAEDSDEAPAGRGGRGGARGRGGRRGAAVPQQARGGGVMEFIPTRLGVALIEGFDRMNFETSLGKPFLRKEMELKMKAICDGHTTKQVVLHESISQYRRVYNQSQENLNVLKAACRQYIFDNAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYA8</accession>
    <name>A0ABR1WYA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RecQ mediated genome instability protein Rmi1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_003112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671045.1">
        <property type="nucleotide sequence ID" value="XM_066807427.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040487"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.770">
        <property type="entry name" value="RecQ-mediated genome instability protein Rmi1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049363">
        <property type="entry name" value="RMI1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042470">
        <property type="entry name" value="RMI1_N_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013894">
        <property type="entry name" value="RMI1_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08585">
        <property type="entry name" value="RMI1_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21000">
        <property type="entry name" value="RMI1_N_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RMI1 N-terminal" evidence="3">
        <location>
            <begin position="13"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="RecQ mediated genome instability protein 1 OB-fold" evidence="2">
        <location>
            <begin position="68"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8088151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="251" mass="27158" checksum="6AF79215ABB98A2A" modified="2025-10-08" version="1">MDLAAQIRSGLQRQGLPTPTLEWVQAVLPNRNPMPPLQALIATAKARLMVVDITNGTVLDASAPALSPNLSNMEVVETKLSRDVLVQVLDIDNLTKSKWEQVEELEAIARGEQTRGREMIRLPAAGEDDDEVSYSSASTQALSSAPGGARGGNGASATPKNSTHRLVLQDCKGQKVHGLELHRIERIGIGTMNIGEKILLKKGATVARGMVLLEPTNCTILGGKVEAWQKAWFDNRLARLKEAIESQGRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WYG5</accession>
    <name>A0ABR1WYG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable acetate kinase</fullName>
            <ecNumber evidence="5">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_003166</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671099.1">
        <property type="nucleotide sequence ID" value="XM_066807481.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040541"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="ACETATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060:SF15">
        <property type="entry name" value="ACETATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="217"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8088205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="418" mass="45659" checksum="1549991FB412CBC6" modified="2025-10-08" version="1">MKVILSINAGSSSVKISVYTAKRGQPPPQLAHAEAQINGLTAPPAKLRYTRGGQTVLKDETVDHKVANQDDAFKLLLKTFIDDPELPQISSKDDIEIACHRVVHGGDYTTSRLINLHTYIHLEDLTDLAPLHNVKALQIVKSCLAELPDAANVAYFDSQFHATIPEHIHTYPINPEIARNNQLRKYGFHGISYQFITNAVAHFLDKNTRDLNIIALHLGSGASACAIKAGASWDNSMGLTPLAGLPGATRSGSVDPSLVFHYASDVGKLSPSSTKELHISRAEEILNQESGWKALTGTTNFGIIASSDEPRCKLAFEMMVDRISAYVGSYYVSLGGAVDALVFAGGIGEKSDKLRRCVVEQVNCLGFEIDEERNAKPILETVQDVGKESAKHRTLVCLTDEQWEMARGCAENPDLWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZL8</accession>
    <name>A0ABR1WZL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_003537</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671470.1">
        <property type="nucleotide sequence ID" value="XM_066807852.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040912"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8088576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="135" mass="14765" checksum="3462FB961C647995" modified="2025-10-08" version="1">MAAFFKAVNAKIRSNPTVSYFCSTHFWGPVSNFGIPVAAVMDTQKSPDLISGQMTAALCIYSATFMRYSLAVSPKNYLLFACHFINEGSQLTQGYRYLSWHNWGGKEKAQAQGAVEEAKAKVAAVGDKVKDVVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WZP5</accession>
    <name>A0ABR1WZP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_003578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671511.1">
        <property type="nucleotide sequence ID" value="XM_066807893.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92040953"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8088617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="527" mass="58906" checksum="B6C8020AA6F694F1" modified="2025-10-08" version="1">MEDAQHDRVSDDEKPDRLTDEIRPPPFPFNLESTWVLAIVWLLLSASNFYVQHQLESYLGLGHILLKASTTLACAAAAAIVYDGVLTFVNEKRVWATREIEFTLASLVARHWRIVLDEDAALEAQKKALMQAGTLQVPRTVFGVTSELGIWALDCALVLVYHISFWQVLAGLLWILRALRGLPDVLVNAALLAALLMCGRFLHLRNTYDKVELTVASSLKGFLGFLKLPVSLDTTKQLTRLLFSAVLTATSWALPTDIIVPFTGQDVTKWAGHVDALKSFIYEKMGTLFSPTFDESWSSAGQLGAQVLLQLGLAAVCFLFVLGYHYLCQEQIVRTWDEVQRGAMNPRDVGDDERYVAAFWRAIALHLISFTAYQIFGAIVSAFELEPLFRLKASPTLNTWGYVLRSRHTLAAAAVWVVSRGLAALATGFCIYAIHYILRQITWLFIRILAAMVMFEDTVMWCSSLTQAALVDWKGHILHIASMDFKLKDKVLLTQGMMNFLFDIRAPLIIVPPNVGIMALDPEVWAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X027</accession>
    <name>A0ABR1X027_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_003719</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671652.1">
        <property type="nucleotide sequence ID" value="XM_066808034.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041094"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8088758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="508" mass="56965" checksum="257CE61C71A1F12C" modified="2025-10-08" version="1">MSIRAHDLSDDLDIKINAGHVENEVGAGTAVPLKDADPKNFMDTYRSYTPEFARETERGLVRKIDSRLMPFVVIIYLFNYLDRNSITQARLYGLQEDTHVEGAMYQTAISIFSAGYIFMQLPTWGHRDMGYREWLHCSDLECCWAPYCSVLPGFGRSPFFPGAIYYLSCWYTKKELGVRMALLVCGLLLSNSFAGLISAGILSGMAGVGHLAAWRWLFILEGLATVVVGVVGYFIIPDYPGTTKWLSEEEKVVAQGRLAADAGNEDGTGEDEVTIWQGIAWALKDHRVWLFACLQMATTASISYSHFFPTLIQQIGFKNSTTVLLLTAPPYLFSFFWAIGFAFDADKRQKRSPHAIVSGVVAMAATVCLIALGEQKWARYALTFFVCAGTFGIYSTTYTWLSSTIVQPRVKRAAAIGIANTCANVASLFANYFWLDKYEPYFRESWACLLAFQALGMACILTLRYTMKRRNRHFEMLATQVDPSDAAAMCRLTEEEQRAVANGYRYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X0H8</accession>
    <name>A0ABR1X0H8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PG997_003835</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8088874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066671768.1">
        <property type="nucleotide sequence ID" value="XM_066808150.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041210"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="12"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="123"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="216"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK8088874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="325" mass="35474" checksum="B7ACA0075C32E4A8" modified="2025-10-08" version="1">MSKSGQRLQDEGTRWQVVTAGATAGLISRFVIAPLDVVKIRLQLQSHSLSDPLSHSGLSRGSPIYKGTLATLRHILRHEGVPGLWKGNVPAELMYVSYAAVQFTSYRSITMLMHRLFGEGTLPKGVESFVSGAAAGAAATATTYPLDLLRTRFAAQGTERVYTGLWRAIRDIQRDEGVKGFFRGIGPGIAQIVPYMGLFFAMYEGLRRPMGQLDLPFSSGDATAGVVASVVAKTGVFPLDLVRKRIQVQGPTRVRYVHKNIPQYESGMVEALRSIVAREGFKGLYRGLTVSLIKAAPASAVTMWTYERVLGLMIDGGQQQEEEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X1Q8</accession>
    <name>A0ABR1X1Q8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_004243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672176.1">
        <property type="nucleotide sequence ID" value="XM_066808558.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041618"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8089282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="138" mass="14893" checksum="5E9329AFA3DA507E" modified="2025-10-08" version="1">MYLPRLLLGRALLSQHPVGDLRFRNPQPINESWDGERAAQKLRPACVGYGPAQWGYELGEAGSLFYILAASGERTGESAGAFSAARHMMASHGREGGLFRAGMMAEGTAFAPKGIDTTGQVRDSLLYSVLGDHERGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2I0</accession>
    <name>A0ABR1X2I0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CCCH zinc finger and SMR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_004536</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672469.1">
        <property type="nucleotide sequence ID" value="XM_066808851.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92041911"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013899">
        <property type="entry name" value="DUF1771"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045124">
        <property type="entry name" value="Su(sable)-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13119:SF12">
        <property type="entry name" value="PROTEIN SUPPRESSOR OF SABLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13119">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08590">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01162">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Smr" evidence="8">
        <location>
            <begin position="583"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="349"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="668"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="423"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="668"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="712"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8089575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="721" mass="77716" checksum="EF3AB36B3AAEBE2E" modified="2025-10-08" version="1">MVSDDTYEICLPVLQDPSLEEEDKTDKLEELLKNETSLSDTAKAEGLPPRPRPLDRLYSDARLPPPGGGGSSATPVSGSPRLGVSPLAPPGFVPSTLSRTKSSTVSPFSSPRPSPRLAFAAPVIPHSPNLNAYEFASDTSPAQEIYGDFQSENVDWLVSDDALSISSSVGTPSGLNAAAPEYVSAQQSDMTPYDMLRSILGQSKTDDEIEEALALHGYDLSATVAAIMDSQGSDSTSATHLTPEAKSILIGKAMTPDGGRPVTPSNQQKSGIICKFYLSQGQCLRADCRFSHDLSNHLCKYWVMGNCLAGATCIFSHDPAHLMNKLSVDESSTPPQKNLSVQDLTSFPALRPTTPELNPFAPSFSFSTNGLTPPPGLRPQNLHANDRPRSRPNSRHQPRESLAAPAIDDNDAFPSLGSASAKPSKKHHGKRGGHGHGHKENLTPSSMADIVKMSPSPAPSVGKPDGKKIGRNGSSTNMRGGENSAAAQAITSPKHIPWLETGEKANKAYLKARQEAIRHGGLRNKFLQSAAQAWNRNDARAAKALSLRGQSENDLMRKAHRDAARELYEERNKAGNGGNEIYVDLHGLHPEEAVEYLERVLLDNSKESRPVYAITGTGHHSKNGKDKVGKAIRNFLNEWRYAYREFSVPGDRNNMGGILGIDARSWDKSLSRDSDGGKEKDEAKEKTDILSQGKEIGDGTVRLLVRDPPKGPSSSGGNRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2U1</accession>
    <name>A0ABR1X2U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_004706</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672639.1">
        <property type="nucleotide sequence ID" value="XM_066809021.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042081"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17997">
        <property type="entry name" value="DEXHc_SMARCA1_SMARCA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1190">
        <property type="entry name" value="iswi atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.30">
        <property type="entry name" value="ISWI, HAND domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044754">
        <property type="entry name" value="Isw1/2_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015194">
        <property type="entry name" value="ISWI_HAND-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036306">
        <property type="entry name" value="ISWI_HAND-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015195">
        <property type="entry name" value="SLIDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF49">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09110">
        <property type="entry name" value="HAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09111">
        <property type="entry name" value="SLIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101224">
        <property type="entry name" value="HAND domain of the nucleosome remodeling ATPase ISWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="192"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="488"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="10">
        <location>
            <begin position="858"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1037"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1084"/>
            <end position="1110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8089745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1118" mass="127401" checksum="2C3AA5DA6564CD67" modified="2025-10-08" version="1">MAPRSRPSAVDTDASMSDAPEPVSRGDAMEVDESFDDSDTNPNTTASSVAGDPVDGRKKRSEANQLRRSIFGKKHDALGESKEDDSIRRFRYLLGLTDLFRHFIETNPNPKIRDIMVEIDRQNEESEKSKKKGSRQGGAATGRVRRTEAEEDAELLKDERHGGSAETVFRESPTFIQGTMRDYQVAGLNWMISLHENGISGILADEMGLGKTLQTISFLGYLRHIMDIKGPHLVIVPKSTLDNWKREFERWTPEVNVLVLQGAKEERHTLINERLVDEKFDVCITSYEMILREKSHLKKFAWEYIIIDEAHRIKNEESSLSQVIRMFNSRNRLLITGTPLQNNLHELWALLNFLLPDVFGDAEAFDQWFSGQDQDQDTVVQQLHRVLRPFLLRRVKADVEKSLLPKKEVNLYIGMSDMQIKWYQKILEKDIDAVNGAGGKRESKTRLLNIVMQLRKCCNHPYLFEGAEPGPPYTTDEHLVFNSGKMALMDKLLGRLQKQGSRVLIFSQMSRLLDILEDYCVFREYKYCRIDGGTAHEDRIAAIDEYNKPGSEKFIFLLTTRAGGLGINLTSADIVILYDSDWNPQADLQAMDRAHRIGQTKQVVVYRFVTEDAIEEKVLERAAQKLRLDQLVIQQGRAQPGTKGPAAKDELLSMIQHGAENVFQTKGATGMAAKGSELDDEDIDQILAKGETRTKQLNSKFESLGLDDLQNFSSESGSAYVWNGENFAAGEKKKDIGMTWINPAKRERKEQSYSIDKFYRQAIYGNSGKAEAKPKAPRAPKQVPVHDYQFYPSRLRELQDRETAYYRKEIGYKVPLADGDEANLEEREAERALEQQEIDDATPLNEEEQEEKAKLSTQGFGDWNRRDFQQFINGSAKYGKTSYEKMADEVDSKSPAEIKAFAKVFWQRYTEVADYNKYLQVIETGEERRSKTQHQRNMLRKKMQQYRVPLQQMKVNYSVSTTNKKVYTEEEDRFLLVMLDKLGLDSENLYDRIRDEIRDSPLFRFDWFFLSRTPVEISRRCTTLLTTVVKEFEDVQPSKNGVNGKSKREPEDEENDEDSILGMAPAKKKSKNGVKNKALDNVKGSKASSAAPSSRASSVASTPSAAPAPKSKSKGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X2W9</accession>
    <name>A0ABR1X2W9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_004690</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
            <location evidence="2 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CGR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8089729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066672623.1">
        <property type="nucleotide sequence ID" value="XM_066809005.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042065"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005579">
        <property type="entry name" value="Cgr1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03879">
        <property type="entry name" value="Cgr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="67"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="67"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8089729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="128" mass="14844" checksum="6D6B221B19F3E813" modified="2025-10-08" version="1">MSGDNAAVAAPAAQAQSQQHQQEQALGMRKNGKQWHAPRKAFRPGSGLTTTSFEKRQSARVAIAAMKAKEKEMKEEKEEERQRRVQAIKDKRAAKEERERFTKMAEKMHKKRVERMKRKEKRNKLLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X427</accession>
    <name>A0ABR1X427_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_005109</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673042.1">
        <property type="nucleotide sequence ID" value="XM_066809424.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042484"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045103">
        <property type="entry name" value="RNF5/RNF185-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12313">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8090148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="248" mass="27015" checksum="E47B3FBB1660EE95" modified="2025-10-08" version="1">MPGATASSTAPPRRSRRLSQVVDLTKESPNRADTLSSSSPVPMGPPAATNTRKRRRSSAANASASGRRASTASTPARPSRRRAPARLASPGGSVFGESSPPPMMAKKEEDDLEVLDLSKADEVPKELQKPAIDKRIKLSKFQCVICMDDVSNLTVTHCGKCSFILCSLLKEHPHHPLLYLSANMLFLGHLFCSECLHSALHIDSNKKCCPVCRSKVEIRTAGKNLKSYYHLELKVMTATRKGKQPVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4B8</accession>
    <name>A0ABR1X4B8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_005222</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673155.1">
        <property type="nucleotide sequence ID" value="XM_066809537.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042597"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="249"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="641"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="641"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="651"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8090261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="687" mass="77805" checksum="CD3793ADEC6ABD3A" modified="2025-10-08" version="1">MFTCRACTRRLLTAVVDHALAAEPTSNALRRSIISTTSTQQQTRSFAAATTAVERTKQQDGEEEEDKPVMSKKDTKALEWSVNKQLEYLSDPFHIANQVQAILDKNRFDEAKLMVLKASKGKNIAVSWNHLIDYEMRRQKLHSGIKLFNEMKKRAQMPTAQTYTIIFRGCALSDHKKLAVAEAVKLYNNMLKSDRIKPNTQHYNSPASGLRPGRRHRHHVHHSAVFQRRGQGPDAFTYTTILNALRAKLEVGPRKTPQQRQKDSAAGSSEKERELSKATSQTIQRAKAIWEEVIAKWRSASLVIDEQLVCAMARILLLGSSADNKAVLELIEQTMGIPRDEEALIKMVREAHLAPPEVDVLQRPSNRMALQPRRPAGGHAAKPGVPTSAKPGNNTLSAVLAALQQTTKTSLVPRYWDVFVRRFGVSPDANNWHQLLRSLRSGHNSSKMAEYLWIMPRAFMTAPTFRIAMNACLRDNLNQHAFHNGSQVFDVMITSLRAPDAHVMRIYLQLAHAVKRPFEDMAKKDPAAAKLAFGKQLVTALENLWEPYKMATKHTSSSVPAVVTTKSDVGREMWKLHATARGEIAALARKMIAAYDRLIFGDLATADTIAKLKPRRNQINAFVVKYFEDREKYEPAWSFKRMQEEKKKEEMEGEDEDDHEFLEGTPRRPQQQQVDPWTRMSRAVNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4Q1</accession>
    <name>A0ABR1X4Q1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA ligase</fullName>
            <ecNumber evidence="12">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_005293</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="12"/>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673226.1">
        <property type="nucleotide sequence ID" value="XM_066809608.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042668"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07900">
        <property type="entry name" value="Adenylation_DNA_ligase_I_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07969">
        <property type="entry name" value="OBF_DNA_ligase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050191">
        <property type="entry name" value="ATP-dep_DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674:SF4">
        <property type="entry name" value="DNA LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674">
        <property type="entry name" value="DNA LIGASE 1/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 12" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="15">
        <location>
            <begin position="637"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="876"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8090332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="912" mass="101173" checksum="CBADEFCA75E86DC1" modified="2025-10-08" version="1">MAPKQATLGKFFGKPNGAKADPQQSTLSFAKATAKKTKEEDTEEEPTEASSSEPTKVKDESDQDAEMASPASDSKKRSRASPVPKSTSRTKSTRSAAKVKKEEEMDVDEEEEAPVSKRPRRNRNKIEEDEDEDEVMADPEPVKPKKSPAKKKETVKKESPKKESPKKAATKKAAPASSSAASKKKNPAEPETKEEEDDSANEESAASESASDVEVDEEEEKPEVAKEARQKVQTKLLQSKAKDPYPDWKEGTPVPYAALCTTFSLVEMTSKRLIITEHCALFLRQVLRLTPDDFLPTVNLMINKLAPDYAGIELGIGESLIMKAIGETTGRSVQVIKQDQKEIGDLGLVAVKSRSTQPTMFKPKALTVRGVHKGLMEIATVSGNGAQGRKVDNIKKLLSAADAYSAGKIDVNTDKGGSSEAKFIVRFLEGKLRLGLAEKTVLVSIAQAVCIHEAEQKGQVPSTSDMEKAEQLLKTVYSELPSWDVIVPAMLKNGIMKLRESCKLRPGVPLKPMLANPTKAITEVLDRFENQTFTCEFKYDGERAQIHYVAKDHQDEYIDGVPGATKEAAKGIASVFSRNSEDLSKKYPDILAKLGTWVKEGTKSFVMDCESVAWDVAEKKVLPFQQLMTRKKKDVKIEDVKVKVCVFAFDLLFLNGKALVEKSLRERRELMYESFKPVEGEFAFATSMDGQEIEQIQTFLEESIKASCEGLMVKMLDGTESGYEPSKRSRNWLKIKKDYLAGIGDSLDLVVLGAYYGKGKRTSVYGAFLLACYNSANDTYETICNIGTGFSEQVLEELHKTLSEIVIDRPKPFYSHSSGGQHQPDVWFEPRYVWEVKTADLTLSPRYKAAIKEGADPAGEKGISLRFPRFIKVRDDKKPDEATGSRQVVEMYRKQESVTKNKGPSVDDDFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4Q2</accession>
    <name>A0ABR1X4Q2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YAP-binding/ALF4/Glomulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_005305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673238.1">
        <property type="nucleotide sequence ID" value="XM_066809620.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042680"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013877">
        <property type="entry name" value="YAP-bd/ALF4/Glomulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040347">
        <property type="entry name" value="YBP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28020">
        <property type="entry name" value="YAP1-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28020:SF1">
        <property type="entry name" value="YAP1-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08568">
        <property type="entry name" value="Kinetochor_Ybp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8090344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="596" mass="66349" checksum="7A152057E0738BA5" modified="2025-10-08" version="1">MPELSEAITAIREGAKEKDRFTYLTILQYNVTSPEVLPTVNEVLEKDPQLTQEIGWDLVQILLRIPGAETCLETVARLGNPREVMIKVMEALEQLSEESGDENALLAEAEEPEPPKDVAARFITLLGMLAILHRRIKTKYPSRFLGSSLVKVYEAYQPTPEMTASVINLVRSLSGRKRPPLPSRKSSINVANPDQDGDASKNAPDPEAEQEDPTEEMMQAKLLQAFVTCILQRYINENEMQWSARLLEKYYPEKNLPGRKTMTQKYTEDDTLQQRDAVVGQFVSILSDLGVDDCSQSFVKSIYEKASGFDPLANFENFDSADEIKLSPGGAVSVIAYWIFSAEVFEANHPSPEMHLFPEHNTLLERFLGADPQSEIVQNPGIADALVTVGLALNHMKLVSATQETKFMAYHHNLTLVSVFHPDLHVRNAATTYAGILLHSDPDDHNRLEILEDLLENCMFATLKAVAVTWLKEEILAANKEGASPNAFTGPEVVDHLQYFIFPDMQELKEMDHEALAEHWAQNNIFLSQVANFGYFLFSSGLKGVVPSGMGAAVAERFVDPLVGGAEKLQQGVPELGEGEKMELAILVDRLRSIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X4T0</accession>
    <name>A0ABR1X4T0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_005396</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000004">
        <property type="protein sequence ID" value="KAK8090435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673329.1">
        <property type="nucleotide sequence ID" value="XM_066809711.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92042771"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8090435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="83" mass="9293" checksum="B1A5659BCD6E7A02" modified="2025-10-08" version="1">MTIHTRSGSISPLSAIQLYKGVSYASGRLEPHIALRILCRVKWNSKRPGLQAVTDEHVLVQRRAAAAAAIRRERSRRKKKCAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X7X0</accession>
    <name>A0ABR1X7X0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_001923</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the avfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673534.1">
        <property type="nucleotide sequence ID" value="XM_066806238.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039298"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF37">
        <property type="entry name" value="OXIDOREDUCTASE MDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8091562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="265" mass="28936" checksum="F01968A5F8674CB5" modified="2025-10-08" version="1">MATYAILGSTGNCGTALIRNLLESSTHARIHAFCRNQAKLYRLLPEVADNKRVQVFAGSVYDTDLLADCIRGAKAVFLLVTSNDNIPGCRLSQDSAASVIQALQKIKAEATPGMKLPKLVLLSSATIDDHLARDMPAWFRPIMLTAASHVYRDLQLAEQYLRAQSDWVATIFIKPAGLSPDVARGHRLTLDEEESFISYLDLSAGMIEAADDDEGRYDGRNVGVVNAKRGHGAKFPSGTPLCILMGLARHFFPWLHPYLPTTGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X814</accession>
    <name>A0ABR1X814_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673525.1">
        <property type="nucleotide sequence ID" value="XM_066806229.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039289"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047128463" evidence="2">
        <location>
            <begin position="16"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8091553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="223" mass="20383" checksum="717AE5787AC5D776" modified="2025-10-08" version="1">MKFSTVLLFATSATAGVLDLGWQRRRVTHDPEAAGTNTGAKVEAPRALALANEVRNANKGSKAGASAAAASSQAAASAAAAPSQAAASAAAAAPQRRPAPSQAAASAAAAAPSQAAASAAAAAPSQAAASAAAAAPSKASSPKKARRSAAAKSAAAAGSQASQAAASAAAAAPSQAAASAAAAAPSQAAASQKARRSAAAASAAAATPASAAAAPKASATLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X8U1</accession>
    <name>A0ABR1X8U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_002219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000003">
        <property type="protein sequence ID" value="KAK8091858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066673830.1">
        <property type="nucleotide sequence ID" value="XM_066806534.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039594"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="245"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8091858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="752" mass="85024" checksum="DAD861895BAB6BEB" modified="2025-10-08" version="1">MEDIDPSFQAKTIELKRALGVHGQLPAHRCQHCEPVLSVLNPPLPGETCSEELFNVTETKAQIGELARLGCKWWSLISSLIRFLLAQKPTLSTAKDHHHIDPYDDLDPELPPALREHRPLWDNAFWNGSHDEQLGKQDLQTVSVTLNRWAPLDLKMEHTVGVFMLGCGSMRANLMFVGHLNSLVRKSEQLVSHINTQPGSVSAFALSRHWLEYCTHVHGCGILDAPTSMPRILIDVKKLGDDNDVRITETGPQIRCPIQDAIKVTRELGFEYLWIDALCIVQDDDLEKAHDIVHMHNIYRNAAFTIIASRSANVTEGFLQLRKAAGAHAPKTIFSVAGDDEANVEANNVIAVLDRHESYEPWDNRAWTLQERLSSGRFLMFGNFQTDWSCRRDEHPYNDCDGWLLHRQRKSFGDAHQERYSLATDIMNQKTTHLDRRSLLQTWYIILKCYAGREITYPKDRLPAISSIARAFARVLDDEYVCGHWKSNLHADLLWINEHIRLETPEISWSWASSSGPISYHRDSWDSTADADFRVLGFTPTFVSNEDPYGAADSAILTLRGLLVALPCSDLPPTTPPTAELAPSFDADQSLDEYKKAQDQLALRDAHQDLKRIVRGEANCWYEFHWDREGILDGSDAKAKGLRAVTEAACESPVFLFASGRFNTWHRNFQTLGGLLLRYLGRQDKFKRVGCFLISPWGHPLMGHHGNDLETARKVLATRIGLDGPEITSEGCTDVIRELWGGIENVRTVNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9R6</accession>
    <name>A0ABR1X9R6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674107.1">
        <property type="nucleotide sequence ID" value="XM_066804334.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037394"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047089671" evidence="2">
        <location>
            <begin position="19"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="279" mass="29638" checksum="7090AE54DB1A9E6A" modified="2025-10-08" version="1">MQLSNLFVSAILAVAVSAEGGDNKGGDHKGANSIGKQCFQMAKLEMITQLGANDTALAAKFNNNQTKIDDFKKKVAESETKLKAMTANATLVGECATINAEAREKGECGKMKFAEKMIAMAGNDTQLAAKFKNNQTKIDDFKKKATAAKADLSAMQGNATLTSFCSVQDTKAKCFKMAAMQKTEEMAKNQTALEAKFKGDETKIKAFQDKAAKWQTQLDAMMANSTLMDTCKTLNKAQAEASNNAAAKDGKKSAAATIDAFSGFITAAFAVVVAGTLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9T7</accession>
    <name>A0ABR1X9T7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_000102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674190.1">
        <property type="nucleotide sequence ID" value="XM_066804417.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037477"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094:SF1">
        <property type="entry name" value="AMINOTRANSFERASE CLASS-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8093417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="111" mass="11885" checksum="E10230BED75F9FE6" modified="2025-10-08" version="1">MPSAAIRGSSASAGGEDQPIAVHAKGDYIRLSDGRQILDACGGAAVTCLGHGNQEVIDAIAIQASQLSYATHGFFDNARRRDLAEWFMTTSDGHFRRAWVTNSGQWTFLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1X9U7</accession>
    <name>A0ABR1X9U7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_000101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674189.1">
        <property type="nucleotide sequence ID" value="XM_066804416.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037476"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="112"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8093416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="142" mass="15791" checksum="C66B29B5D5DB0E66" modified="2025-10-08" version="1">MNNSLRTDICQYACRYWVYHLEHSGTQLCDGDEVHNFLTRHFLHWLEALSLMNRVSESLEILATIRGLTSSLAKQLDAFFDDANRFILANGSVILVAPSQIYSSGLLFAPKQSGHSGSVYSVVFSHDSQLVASASSDHTVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAT1</accession>
    <name>A0ABR1XAT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Minichromosome loss protein Mcl1 middle region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_000501</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674589.1">
        <property type="nucleotide sequence ID" value="XM_066804816.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037876"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057646">
        <property type="entry name" value="WD40_WDHD1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022100">
        <property type="entry name" value="WDHD1/CFT4_beta-prop_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048591">
        <property type="entry name" value="WDHD1/CFT4_hel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20946">
        <property type="entry name" value="Ctf4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12341">
        <property type="entry name" value="Mcl1_mid"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24817">
        <property type="entry name" value="WD40_WDHD1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDHD1 first WD40" evidence="9">
        <location>
            <begin position="12"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="230"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="7">
        <location>
            <begin position="413"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="7">
        <location>
            <begin position="493"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 helical bundle" evidence="8">
        <location>
            <begin position="720"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="681"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="697"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8093816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="835" mass="93052" checksum="677156E1B7438D73" modified="2025-10-08" version="1">MASTAPLRPRARPAHTQGSTHCAYTPNGSRLVSVGSNNTIRLYKTGFDGEPTNIDDCQEQNVSVDASDEFFVVGSEDGTVSLYSIPDATFDKFLLRCSLPVRDVALSPDSKWCAVASDELTVKVVRTDDNSEVRHLKEHNKPTKHLAFDNKGSTVTLACTDGILYVYSLTADEPELIKKVDGIIGALDTDSELSSMVAWHPDGRAFAVPTPTREIQVVSKNDWEKQRNFARGHNGDITALAWSPNGAILASAGKDKKILLWETKTQSVIARLDYANVMSISWHPSDNLASFTNSDGEVYIHPDFVPEQFAQMLRLPKQPAPFIHDPMEDISNNARKVDLNGIPSRPRRDSLDSYDSLMDGPLDGPLPEDDDFVVDDDGAGYALNVNGKRAHAGPEGFLHRSSKRQHLEAQYHEAFQPGSTPWRGNRKYLCLNLIGFVWTVDQDGHHTVTVEFYDHEFHRDFHFTDTFLYDKACLTENGTLLSCPPKNDTPATGEAVLAMSLSESFITVTTTAGYVRVYTLFGIPYRVYRPKSTPMVTCASWKDYVLTMGNGPIGADGNTRLLYTIENVKRDEICQNEDTVALPEGATVKSIFFSDQGDPCIYDSTGTLLTLLHWRRPSRACWVPLLDTKLLPRLASGRKHESYFPIAVADNKFHCIILKGGDQYPYFPRPLLSEFDFSVPLTSEPPKSKKKSRANNDDMDMDQDSDEEEDVEGGSSETRKLEQQYLLKGIEASQLQDLIDDVTGDSGSSSAGQRSTLARLELDIDKTLLQYLAIECREGEDRGMRALELVRLMRDRSGRMIEAAGKVAERYGRTILGDKIREIGERRVVGFEDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAU6</accession>
    <name>A0ABR1XAU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromosome transmission fidelity protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_000516</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674604.1">
        <property type="nucleotide sequence ID" value="XM_066804831.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037891"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031342">
        <property type="entry name" value="Mug163-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094:SF2">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17119">
        <property type="entry name" value="MMU163"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8093831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="35300" checksum="3A722956136AE1E6" modified="2025-10-08" version="1">MSLPRGFFQTPPQILSSSASGAKHLIRPTVPSQHLASSHVAGSSVTASVPLALSKPAQPLATVPAPFAPPPSHHDPSPIWFDSAVTARFSANGGKPEDERRVKLGRTLRVLHDRLPSLLQSPLPQEILAPNISLHLFPSTHPYLPAVSGRVGYIAALWTSPIAWNRVPIIGNLKLEILSERMTTQPLYYSPRRTGAYDEQLVVKWRTADNNKNNGSSTSSLAQRGEHNLDHALRGTLSPGSKKEFTGLFIFEFDSEGRIISHTIEHVDQNSEWEKGVGAKVVHLADWLLGGIKGRPPPQGACPMFLKVRRDRRDPRDPRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XAZ9</accession>
    <name>A0ABR1XAZ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Vesicle transport V-SNARE protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_000454</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VTI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674542.1">
        <property type="nucleotide sequence ID" value="XM_066804769.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037829"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF26">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="127"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8093769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="225" mass="25336" checksum="08762D258138147D" modified="2025-10-08" version="1">MANPLDTDAGSELFSSYEAEFKLVQADLTQKLDQIPELSGEPRKAAISQGERALEEADELLGAMRLEKANIPSASRTKINQRFRNFETDVDKYRRKLRSLADDRAALFGSRYTDEPASDAQAEQRQQLLSGTDRLDRSTQRLRNSQALAHETESIGASTLADLHTQRERISHTGNMLMESEGYVDRSVKTLRGMARRMATNRIITIAIITILVLLIFAVIYSKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XB21</accession>
    <name>A0ABR1XB21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA recognition domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_000548</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8093863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674636.1">
        <property type="nucleotide sequence ID" value="XM_066804863.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92037923"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12347">
        <property type="entry name" value="RRM_PPIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034168">
        <property type="entry name" value="PPIE_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037">
        <property type="entry name" value="ATPASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="9"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="113"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8093863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="153" mass="16555" checksum="A6A0ABE9D82325A4" modified="2025-10-08" version="1">MTDSARWKATVYVGGLAGMVDQSNLHDAFIPFGEIADISLPKNDKPDATEPHRGFAYIEYEDADDAKEAMDNMDQSEFFGKILKVSAAKAPKSAEEGLGSKTALWQQESWLAEHAVDEEDRTAADGAKGAVDDRPEDPMQGLEGLDVAGPKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XBK1</accession>
    <name>A0ABR1XBK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">CDF family cation efflux system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PG997_000706</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066674794.1">
        <property type="nucleotide sequence ID" value="XM_066805021.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038081"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF5">
        <property type="entry name" value="DIFFUSION FACILITATOR FAMILY METAL ION TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="12"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="11">
        <location>
            <begin position="270"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="140"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK8094021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="399" mass="43100" checksum="FED9EC93442FC8BF" modified="2025-10-08" version="1">MGFTLTKSRRLAIIICISFTFFVAEIAVGFYTGSLALVADAFHYLSDVIGFIVAFSAFKVSEREEFSPSLSFGWQRASLLGAFFNGVFLLALGVSIFLQSIERFITIQPVENPKLVLIIGGVGLGLNLISAVFVGHDHGHGHGHDHGSHDHDHDHGDEPHDHAHEHEHGDAHSHSDHTGTNVHGEHLHTTKRTDSKPGFDFGMMGVLLHVLGDAINNIGVMVAAIIIWFVKGDQRFYADPAISMAIALMIFVSAIPLVKNTGKVLLGHVPNNINVEEVRHDIEKVPGIESLHELHLWSLTQEKAIATAHVSVPEDTSVDSFMGLAKTVSECLHAYGIHSVTLQPELPAPGSVYNANSIDLARQTATAGDSGAEARRRAVPQSCQLTCGKDKCANLGCCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC57</accession>
    <name>A0ABR1XC57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_000970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675058.1">
        <property type="nucleotide sequence ID" value="XM_066805285.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038345"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF47">
        <property type="entry name" value="ENDOPEPTIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01220)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="3">
        <location>
            <begin position="90"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="454" mass="49195" checksum="CF207908DAC09B3E" modified="2025-10-08" version="1" fragment="single">PIPQSDIVPSLSIPGVEIRRARPFSNTLKAAVAKKSSGSHAKLRRLPKSHSHRQPSGAAFFAEHRQSDAGTGATTPTGNVSVVDHSATQYSVEVILNGSPFNLIMNTAGSDTWVRSRNFTCLNNATGSAPRSQCDWGKSGATGFPKGPIQNQHFAIKNADGSGVSGQLGYMNVSLANVAVPNQEVAIATQGIWHGDNVTSGMLGMAYPSLTSAYSGDDMNDTSDESALEYSPLFTTMITDGLVPPLWCLAISRNSSDGIFCLGDNKPSNLTRDYFAKADLLIAKLSDKKAAAYQPSYYATVFDGFRIGTTDIRESYPMILDSSTTLAYLPPGEHIAPKNKDTYLLLTHYTDVAETVNSHFQPPATYLWYYGSYFVPCDATPPYFAVMLQDSPFVVNPKDMINQDVVDPWTKMCQTGITMGTDGLYILGLTFLTNVAVGFDIGNANIYVYPRAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XC73</accession>
    <name>A0ABR1XC73_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_000985</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675073.1">
        <property type="nucleotide sequence ID" value="XM_066805300.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038360"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="490" mass="52911" checksum="C7A1B04C05B965E4" modified="2025-10-08" version="1">MSDGPHLTQASDIATIVPALSRKFDALGLIAWFSAAYFFPQACLAIGFGRLAAVANTRMLVVIDGMLLIVGSILCIVANSASIFIIGRVITGLGIALGFPLCATILICITSPNERPLYMAGCVGVDVMSLAFGSLLGGFFETNIDYRWVFALTIFGAVMSMVFIYPFQQPARPTDHLSVWQHLRRFDFLGFGLFLVCSICLLLALQMATQSGRWDSTPVIVLFALFTVTLPIFILQQRTHCHPDDRLLPRGIFSRDMSLLLGFGFFTMFAMYGVYYYLSTYFQSVHGLSSFDTGVCLLAFFITSGVASLATGVSTEFVTYANTIILTGVTLALVGSALLTTLDQSTSRVKASLLTMISGFGFGTAQTLAVVFSQSWVAEHLQPLTVSIALMMQLLGGTLGLVLGGSLLNMRVRAGLQHLHGKLSEAQVAEIAQGSLPPEVMESLPTPVTMEVYTMMAQAVQNIFYTATGAVAVAGLLAVCMRWHKIKTNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCI7</accession>
    <name>A0ABR1XCI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vesicle tethering protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001059</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675147.1">
        <property type="nucleotide sequence ID" value="XM_066805374.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038434"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006955">
        <property type="entry name" value="Uso1_p115_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024095">
        <property type="entry name" value="Vesicle_P115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006953">
        <property type="entry name" value="Vesicle_Uso1_P115_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013:SF0">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04871">
        <property type="entry name" value="Uso1_p115_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04869">
        <property type="entry name" value="Uso1_p115_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vesicle tethering protein Uso1/P115-like head" evidence="5">
        <location>
            <begin position="340"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Uso1/p115-like vesicle tethering protein C-terminal" evidence="6">
        <location>
            <begin position="892"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="703"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="890"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1004"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="711"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1012"/>
            <end position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1038" mass="115507" checksum="61384D557C492AE6" modified="2025-10-08" version="1">MFSSIATAPAKQSVGETITVLSGRLSSATLLEDRRAAILGLRSFAKEYPASVASGALRSLIGSLSKDGEDVDTVKVVLETLLMLFNPNQDSPEASEEIALWLADEFTQRQENVTLLLDFLETSDFYSRLYSLQLLSAILSARTERTEECVFTAPLGISRLVAVLDERREAVRNEAISLLTYLTPANPDIQKLVAFENAFERIFAIIAAEGGLVEGDRVVEDCLILLANLLRLNASNQSAFRETGCVLQLSRLLESSYQPPKEAEEMATWAQQQGNRNIYALLAVIRLFLVQGAVGTLQNQNAFWQHGVLYHALQLAFTQTTELFIRAEALSTCADIIKANPKLQESFAQLQVPSVLEDVMPMNGQNGNANGPVVVYVIDGLLDLTLSITALQAFDLRLAACQCIKAYFFHHPEIRLHFLRRAIDGHTSGRDETANVLSTLLQPSGQVTSSDPYRHWFASVILMHLIYDNAEAKALAMSVTEGDAESGEEVVTSIQTITAHLISGLARPNSERTVDERITVGYLMLLLGWLFEDLEGVNDFLGEGSNIQSIAQAVHQAPNGSLVQGLCAMLLGVCYEFSTKDSPIPRSTLHDVLLQRMTREKYIDVLTKLRSHPFIRDFEVMPQKLDNSGNLPEVYFDATFVDFFKDNYSRILRGIDREPGMEISVVTNGVQKGISRELVDSLRAQLEEKERALQSALVDVTSSDQRLGQEQADHRRSKESSASELARIKEINEALQRGHEEEIQRITAQLKTQEDIYQRQLEAARREAKNAADKIYEEHRAKEEELQRQLEYVKKTAEAATARAQRRAETELADAKKNSEAELAEAKKKAETEVAEVKKTAEAQTTRAQRRAEADMADLRATISRFETDLMKVKQVSKPCANKAKADELRSAQEEHAATLKAAQEAHTSKLDAETARATAAAAKAKAAEDRVAELEKQVTDLEKRIAQRDDNTKKASRWIYSTAAEAQLKAKDEEKAAVQTELDDLLMVFGDLEEKVEKYKKRLKGLGETVSDGEGDEDEDEDEDEDEDEEDDDNEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XCM7</accession>
    <name>A0ABR1XCM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hemolysin-III channel protein Izh2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001104</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ADIPOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675192.1">
        <property type="nucleotide sequence ID" value="XM_066805419.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038479"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF52">
        <property type="entry name" value="ADIPONECTIN RECEPTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="314" mass="35420" checksum="B58339E99C15BFEB" modified="2025-10-08" version="1">MMAILPIPKKKRTASELSADAESYGSPTHGKHPDLLLFDEIPEWARDNKFVRGGYRPESGSVRKCVQSWFYLHNELVNIHSHLIPAVLLFLGELYLIAPLPFRYGHVSLGDYLIIAFFLLSTTVCFGLSAMYHTLMNHSHRVEAQCLKLDFLGIIVLILGAFFSSIYCTFWCEPDLRQIYWATVGGLGAISVIVLVHPKLQGPRWRTLRLLTFVCTGLAGIAPFVHGGIKFGFPQMALQSGLPYYMTEGVLFLMSALIYGETRFPEKFWPGRFDMFGSSHQIFHLIVVAATVFHLAGVMTALDYNFNSRYCSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XD19</accession>
    <name>A0ABR1XD19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Disintegrin and metalloproteinase domain-containing protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675358.1">
        <property type="nucleotide sequence ID" value="XM_066805585.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038645"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04271">
        <property type="entry name" value="ZnMc_ADAM_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034028">
        <property type="entry name" value="ZnMc_ADAM_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00200">
        <property type="entry name" value="Disintegrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57552">
        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045870021" description="Disintegrin and metalloproteinase domain-containing protein B" evidence="4">
        <location>
            <begin position="22"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="677"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="6">
        <location>
            <begin position="272"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="5">
        <location>
            <begin position="484"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="729"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="772" mass="82710" checksum="B2FC95B6FC27C95E" modified="2025-10-08" version="1">MRGILSTAIAFILALAPSSEAHSTKRNALNYLSRLDDPTLHTPSHRVHAHSSFELTFLLHDKSDKIRLTLEPNHDVIADTASVQYLASDGTIRHEEPIARSDHRVFKGHAYVQHPGHQEWINEGWARITVHRDGPKPIFEGAFRVNGDNHHVHTSTNYRKTQHHEDPVVEFAEDEYMIVWRDSDVKLDPFEEDMPGELKRSLRAPSCSSDSLEFNNENTHPIFTGLDLRDTSVVDSARLFAREGIDGYKGGNGAGVNLASTIGSTAGCPSTRKVALVGIATDCTYTAMFNSTSSVKAHIIQQVSAASQVYESTFNISIGIQNLTISEADCPAWRGQFKDRNAYWTLLSTCNTGAAVGLAWLGQLCAEGASPSGEGNETTAGANVVVRTDTEWQVFAHESGHTFGAVHDCMSQTCSDGTVTQNQCCPLSSNTCDAKQQFIMNPSTGNNIDRFSACSIGNICSAMNRNSVKSSCLSNNKDVVTITGQQCGNGIVEAGEDCDCGGEQGCGSNSCCDAKTCKFKGNSVCDPSNEDCCTQQCQFASSGTVCRESTGSCDPAETCSGNAPTCPKDVKAEDGQKCGSDGAGLTCASGQCTSRDLQCKTIVSNLNGDNSTKSCGSGGCTLSCASAQLGPNACYTLKQYFLDGTPCDGGGKCNNGKCEGSNFINQAQAWINDNKQIFIPVVAVVGGLVLIALLSCLCSCCRRRPRRVMKPTQPNPSWQGGGYGGGGAWQAANVARPPPAYGQPPDWSPYQQQQQQQQYGGGMRRVASTRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDA0</accession>
    <name>A0ABR1XDA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_001289</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675377.1">
        <property type="nucleotide sequence ID" value="XM_066805604.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038664"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoreductase" evidence="6">
        <location>
            <begin position="92"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8094604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="353" mass="38813" checksum="BE8E5FDF8CA8DC40" modified="2025-10-08" version="1">MDHHPRPPQMRDSWFAPITIDLLLKVLNVTIFHPFIAWLIPLCFRAEHMDYDAMPMRLTIAWAFAVTMVWMGNQLSHKIAYGMPREVDLSEDVIVVTGGASGLGLLIAEVYGMRGATVAVLDTADLEATDARGITYYKCDVSDKAQIAKVAADIERDLGLPTILINNAAEVVGKKLLDMEAEEVERSISTNLLSHFYTIKQFLPGMLRNETGGTIVTVSSVIGHLGSAQLSDYAAAKAGVTALHKSLAAELYEMPEIKTILHPAVPRRQDPHPFIAPVVEPVDVAKEIIAAIDMGLSDHIAMPLYARWVDWYNVLPVGVQRLARRFSGVDQGMKTFVGRKGDNVASEKKATLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDF4</accession>
    <name>A0ABR1XDF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_001288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675376.1">
        <property type="nucleotide sequence ID" value="XM_066805603.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038663"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053083">
        <property type="entry name" value="TF_kinase-domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305">
        <property type="entry name" value="SI:DKEY-192D15.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305:SF24">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE C03B1.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="136"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8094603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="616" mass="68413" checksum="2E98BDD9D82D40E5" modified="2025-10-08" version="1">MWWDTARIEATVTRQFACDQLLPDETQKLDQALGFGGGLTDGTYWEWIREKAPRIFLIMVDLGIPDQIFNIVDDSWDDGDLPIPLDQIEHLALRATRNGKVDRRFYYRQFHYLVRTLEKGGHTVYSDDEVIPLEVVDRRPVAGLSQNHSVDKVELPNYPGEVFSRRRIPVGTAPGTLSESDFLWEINCTKNVQNGHLVSYFASYTHQAFGYVLFIPASDYNLKTILGALPAPLKALSKQDRRVHIMNWIHCLVDTLCYLHSRGWAHGQIKPSTVLFNSKHDVFFTDLSRLSAETLANSSDKAAFDKESYIYAAPEQWFRPSAGAMNLQRRPPLSSPPSSPPGDYAFSIQRHGSEPASNSTPAVHTTTPNLNPQAADIFSLGCVILELLSLQMKRQTRSFASHRAAKHKTPGRGGAVPDSSFHKNLGQVESWMAGLAKDASKKSDAVFRGVAPLCRVVARMLSVAPQDRPTAQEVEQETYKVLRESGINEPHCVHQYGGGGLDYGMSGLHISKETNKKTATTAENSAAVVDVEDDEFQYNPPVIIGKRPSMVGRPTGASTSSKADYYATQEYKRTSSSNSSGGAKDRDSPTLSGFDAIQNIRLNKVRHWQAPAYTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XDT0</accession>
    <name>A0ABR1XDT0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase-activating protein GYP5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_001525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675613.1">
        <property type="nucleotide sequence ID" value="XM_066805840.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92038900"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="418"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="790"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="456"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8094840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="892" mass="98776" checksum="99704FB67FEE8C4D" modified="2025-10-08" version="1">MAFPQDTFEDAVDARSVRSLTKRSSSAYKLAAAPSLKESLKDEEPEAVPDKPTLDVVVPEPEAEEEKVQVNGDSDAHDAHDAHDAHAAHDTHDTHDTNDAHAAHDDDEAPAPPEKDVEPVVEEEDDLHKESIRAPSVISTNGTLDEVKLDDMKMDEVKLDDGDETPSVAKEEVVVEEEEKPPAVPPKRPGKKLSLGNLMPWSPTNATESPPKDTPSPSTTSANLSTPRDSLVADKPPGISRKLTSPFTWLSSRNSKDNSSPPASIPRTTRRDTTSSMATLNSNPEMMLSKLEEGDENGARPKSVRNSLKDRFKLVRMREEAGIVLPDEDASSIQGALPTPIDTTNLGAETIDAGPLSPIPPTPNPDLAPGTVSGVMAGPSAINDSQVDWDLWQNVVYEGPAAVARTSAEELNQAIATGIPNVIRGVVWQVLAQSKNDDLELAYRDYLARGTEKNPNRNSNSTSISSLSNGNLSIEKETLTSSASSVHSEKSGSNGTKSPVPSEKDVEAIQRAQAVAAAEQKKKDKDDIIKVQKLEKVIRKDMGARTSYSKHAQAAGLQDGLFGVCKAYALYDEAVGYAQGMNFLIMPILFNMPEEEAFCLLVKLMHEYKLRDLFVQDMPGLHMRLYQFERLLEDLEPALYCHLHRRGITGHLYATQWFLTLFAYRFPLQLVLRIYDLILSEGLAAILKFGIVLMQKNKETLLGMSDMGQLTTHLKDKLFDVYVDQAPSAGSILENGFFGSSSASVDKEVYRADQLVRDACEVKVTPELLKAYTAEWVEKTRSEKERQQELERLRSQNATYAVQVRKLEKHVEESERDQVEMANQFVRFKLQEEKLEEANEGLEQKVKELSGIINEQQRTDEQLVATKMQLAELTSEHEALKRKWAELKKQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XE76</accession>
    <name>A0ABR1XE76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675765.1">
        <property type="nucleotide sequence ID" value="XM_066805992.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039052"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="169" mass="18311" checksum="AAD96D27328D534A" modified="2025-10-08" version="1">MSQSTGKQNDDGNLYSLMRQVITDIGALKKIQRLAGSAIDAMADVFDEFQARISDLEIGLHTNHAKTAGQARFIVQMCHNITVCQRDAATIASRIANVGKHVEINYATLAPATFVDGTPEIIQLPARVQRTTAQWGGITTETSTNEGASQAQKAPVAPQQAENIYDRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEH1</accession>
    <name>A0ABR1XEH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mating factor alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_001669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8094984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675757.1">
        <property type="nucleotide sequence ID" value="XM_066805984.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039044"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045915698" description="Mating factor alpha" evidence="1">
        <location>
            <begin position="19"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8094984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16159" checksum="6D8D22488EC11379" modified="2025-10-08" version="1">MKFTAALAIAILGLTVTALPLDRDVEHAHFKEVQAEPADNNVDAAATRAGWLYIKERDVEEAQDNNVDAAATRADWLYIKRDTEAVHAGKAVPSAEPADNNVDAAATRAGWLYIKERDVEEAQDNNVDAAATRAGWLYIKERNAAEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1XEN7</accession>
    <name>A0ABR1XEN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_001773</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000002">
        <property type="protein sequence ID" value="KAK8095088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066675861.1">
        <property type="nucleotide sequence ID" value="XM_066806088.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92039148"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8095088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="159" mass="17356" checksum="82FF4694EE8FF106" modified="2025-10-08" version="1">MPGGAAKSLLFELRERPDLIGAKVGEPPSTGLESNAFSFDACSKSCRMWPAKNEMNETPTSASGPLPRADQRCIPWSELWSSIVVIAREAPLMAHDGLQGIIPRISPSAPWRTGPRPLVEFSHVRLGVCISHLIETWAKLESRSARMAQQNHRAAGITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UQ70</accession>
    <name>A0ABR1UQ70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase C14 caspase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000011">
        <property type="protein sequence ID" value="KAK8061061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660481.1">
        <property type="nucleotide sequence ID" value="XM_066819596.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052656"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8061061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="249" mass="28152" checksum="368476C59B332F25" modified="2025-10-08" version="1">MDGNWLKSTNEEVLVSIERRDQLKPKVLVLYWETGNVGFKTECQAVREMFEETFHYPTEEFAIPSKNVEAATPNQTLEYELMSRVTKLLSEATHRSTLIIYYGGHGDEDHDKHRGQECQSVWAEFEAGGSTLRWYKIQELMRESSADILLILDCCFAAQAARGRNDRRGRFEILAAAAMGMPTRGPGKKSFTTVLLEDIHEEVAKGGVIEHQGHTYSTLHSAKGPLRYASPYSSNRRTNLSQTRASCCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UT65</accession>
    <name>A0ABR1UT65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histidine kinase-group xi protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014223</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066660725.1">
        <property type="nucleotide sequence ID" value="XM_066818537.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051597"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF60">
        <property type="entry name" value="HISTIDINE KINASE G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="494"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="648"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="981"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="1058"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1140" mass="128575" checksum="00CD876095EB44EC" modified="2025-10-08" version="1" fragment="single">RARCLRGACSPQLQLAGQPRHENLTEFQQFVLNVDWANTSVGPIEQWPQELRQLLRMVIVDSAPCIIYWGEKFTIFYNEAYIPLIGNNHPTIMGKNAADVFPDFWNFFDKIITDQRLTAEPAQGDASMLLMERHGFLEETYFDWKLVPLIGENGEVMASYGTPRDLTMHVINKRRSDCVQQLTHKISRITNLEDLWATTLAGLSQDERDLPFALLYSVDQKPSMLAPPSNPSLTCHLEGTIGVDQDHELAREYLNIRHDLDGFGPVVVEALEKGEMVVLKSDHPSLQAAQGRRLEGLRLTQRAVRHCPDQGRMRNRILLDRRPQPLPALQPGLHGLPALYREAIASQIAKIRLTDEVRARAELIKKAKMDVERSEWRFTKFAERSLVGLAIAQPDRNILYANDAWYRFAGVPPGTTEYPKWLENVVDEDKPLVEEWYSRVLTEKKGASSNSDAIYADLDEFGEVGSVMGLTIDISEQKWVEQQLLIRSKELEESEGKWRNYAEHCPLGIVRTDKDGYVEYGNDAWHGYYGFTRGEVHGPQPWTPYIDEAQVEPWKECWKRLQTEAHPFSMELKLKDKVFRMEDGDEIIESSVWILVTGFTEFKADGSVDYIDFWVTDISAQKLAEKLLTDKMDEAIRLKTHQERFIDMISHEIRNPLSAVLHCGEEVVEAMQNLRSHLDSAIDSANTIMYCVQHQKQIVDDVLTLSKLDADLLVVSPIPVQPVTLVRTSVKIFEPELKMTGISLTISEDPSLKALGVDHILLDPNRFLQIAINLVTNAIKFTKNAAVRNIDITVSALAHPPTEQELGVQYVPRRYEEARPVSPTHENRPEFDVWDEAVYLCFSVKDTGKGLTEEETAVLYKRFSQASPKTHIEYGGTGLGLFISRQITEMLGGQIGLHSDAGDGCTFAFYVRTLKGSAPRRASVSVEPIIQMTRTLGLTTTAAPLVVAPDQNGGAPIDLKLVPTVPPPALLVTTAPKTERMVLVVEDNLINQKVLCKLLRKRGFIVEAANHGQEALELLGHPSLTPSPSLEKEEDIEEAKRELRDVSLYRRFEVILCDIEMPVMNGIEFTKSVRSLEQEKELPGHKPIIGVTANVRGEQITAAIESGMDGVTTKPYRIDDLIAHIDRVCEALQKKDKRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UU60</accession>
    <name>A0ABR1UU60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit H</fullName>
            <shortName evidence="4">eIF3h</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_014565</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661067.1">
        <property type="nucleotide sequence ID" value="XM_066818879.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051939"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08065">
        <property type="entry name" value="MPN_eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03007">
        <property type="entry name" value="eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027524">
        <property type="entry name" value="eIF3h"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045810">
        <property type="entry name" value="eIF3h_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19445">
        <property type="entry name" value="eIF3h_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="13"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8062468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="361" mass="40405" checksum="0E5708729EAAA2F9" modified="2025-10-08" version="1">MADAQKEVPFKTVQVEALVVMKIVKHCANQFPTAATGSIVGMDQSGVLEITNTFPFPIADVAGLDGSHQNDASALAAAAPRAKANVVYQSEMIRHLKEVNVDANNVGWYTSATMGNFLNSSFIENQFHYQKENDKTIALVHDVSRSVQGALNIRAFKLSEKFMAAYKEGKFTTESLQKSKLSFKEILVEFPVNVHNSHLLTSFLHQLPGVPSKAEATMPTSLADIRRADQKTPLYPSVDTLELSIDPFLEKSCDLLLDSIESHYTELNNHQYYQRQMAREQTKITAWQTKRKAENAARVASKQQPLPEDEWQRIFKLPQEPSRLEGMLNAKQVEQYSKQIDGFTANVSAKMFAVRGNLLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUN5</accession>
    <name>A0ABR1UUN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Serine/threonine-protein kinase TOR</fullName>
            <ecNumber evidence="12">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PG997_014737</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="12"/>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661239.1">
        <property type="nucleotide sequence ID" value="XM_066819051.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052111"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05169">
        <property type="entry name" value="PIKKc_TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.150">
        <property type="entry name" value="FKBP12-rapamycin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009076">
        <property type="entry name" value="FRB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036738">
        <property type="entry name" value="FRB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024585">
        <property type="entry name" value="mTOR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026683">
        <property type="entry name" value="TOR_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08771">
        <property type="entry name" value="FRB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11865">
        <property type="entry name" value="mTOR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01346">
        <property type="entry name" value="DUF3385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01345">
        <property type="entry name" value="Rapamycin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47212">
        <property type="entry name" value="FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="16">
        <location>
            <begin position="1382"/>
            <end position="1990"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="15">
        <location>
            <begin position="2165"/>
            <end position="2482"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="17">
        <location>
            <begin position="2547"/>
            <end position="2579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2485"/>
            <end position="2519"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="913"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="2505"/>
            <end position="2515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK8062640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="2579" mass="291906" checksum="181630831B4B47EC" modified="2025-10-08" version="1">MSVPVNNPTAAAQQALNNALDDIVKDLKAKHPSSDRASDEIRKHAALRLREMVVSKSKGGVLGGEHERSKDGNEQPGSACQAELWCEIAAWKFGGSLIRRAVTLEATAWFKLPLGPNNLALNPSKPNFRTWSWFANACVVSDLGTDQFTYFYNNVNQKITQLIHSSVPADRLGGVYAMDALADFDAVDATIKYTRFMNNLKTILRGQDTVPMQPAAIALGKLCRPGGSLISELVESEVKTSLEWLQSDRVEEKRYSAVLVLRELARNSPTLMYQYVGLIFELVWVGLRDPRQLIRVASGETVCACFRIIRERDQEMKSGWMHKMYNEMISGLKINTIETVHGSLLVLKELLEQGGMFMQDHYMEACEIVYRYRDHRDPIIRKTVVVLTPDLANYAPSEFSHQYLHKFMVYLSGMLKKDKERNDAFLAIGNIANSVKSAIAPYLDGVLIYVREGLSIQSRKRGSVDPVFDCISRLAVAVGQTLSKYMEALLDPIFACELTPKLTQALVDMAFYIPPVKATIQERLLDMLSKVLCGEPFKPLGAPTPNTLASVPVIPKDPKDPQAYEHRKAEVKLALNTLGSFDFSGHVLNEFVRDVAIKYVEDDDAQIREAAALTCCQLYVRDPIVNQTSYHALQGVADPEAGIRRTVLAALDERFDPHLAKAENIRTLFYALNDEDFSIREVSISIIGRLARYNPAYVIPSLRKTLIQMLTELEYTDVARNKEESAKLLSLLVQNAQGLVKPYVEPMMAVLLPKARDTSPAVAATILKAIGELCTVGGEDMLVHKEKLMPIIIDALQDQSSTAKREAALHTLGQLASNSGYVIDPYLEYPELLEILQAIIRSEPQRGPLRQETIKLMGILGALDPYRHQVFTRFFDELNSVCTIDKWRYKYTPKRPNEYKYAFEKDPQKDWEYANRNRTLQQVEERIPDAKQNVEATRMTDISLMMTGLTPSAKEYYPTVVINALLNILKDQSLQTHHAAVVEAIMNIFRTLGLECVPFLDRIVPAFISTIRTCPDTKKEPYFSQLAGLVNIVRQHIRNFLPEIVDTLQDFWPKSSGPLQSTILSLIEAISRSLEGEFKIYLARLLPMMLSVLDKDTSPKRIPSEKVLHAFLVFGASAEEYMHLIIPVVVQTFEKLGQPTFLRKSAVETIGKISRQVNLNDYAAKIIHPLARLLASGADMSLRHAALDTLCALIQQLGKDYLHFMGTVNKVLQTHPIQHQNYELLVSKLQKGEVLPQDLSSETQFVDQQDEPIFAELGSKKLEMNAIHLKTAWDTKGKSTKEDWQEWLRRFSTTLLTESPNHALRACAVLASMHLPLARELFNSAFVSCWSELYENYQDELIVNIEQAIKCEHVPPDLLGLLLNLAEFMEHDDKALPIDIRILGREAARCHAYAKALHYKELEFLQDQSGPAVEALIDINNQLQQYDAAIGILRKAQLYKDGIRLRETWFEKLERWDEALESYNKREANVPADQAIPIDIVMGKMRCFHALGEWDALAGLAGNTWSNSAPEIQRLIAPLATAAAWGLGKWDAMDNYLQSLKRHSPDRSFFGAILALHRNQFREAAACIQQTREGLDTELSALVSESYNRAYQVVVRVQMLAELEELIVYKQADDKKKATLRRTWEVRLQGCQRNVETWSRMLRLRGLVLAPHENMHMWIKFCNLCRKSQRMGLAEKWLKQLIGTEAPLESVIPYWSDENMPQTPNRRVMSSPPPIMYAILKYQWEYGQTPDLRKQEYPEKTLSCLRAFTADISRQFDVVRSSIQPQVPNELGVLGPVNEFGYPVSNPQTQAQRVNMRSMDELNEYTHLLAKCYLRQGEWQVALNKDDWQYHNVQDILTSYSKATQYNPKWYKAWHAWALANFEIVQAIGSPSANGAISRMDPAVVVGHVVQAVQGFFKSIALSSGSSLQDTLRLLTLWFAHGGSSEVNNAVVQGFGTVSVDTWLEVIPQLIARINQPNSRVRQSIHNLLSDVGRTHPQALVYPLTVAMKSSQSTRRSRSAAQIMDSMRAHSPNLVEQADSVSHELIRVAVLWHEQWYEALEEASRLYFGDQNVDGMFSTLGPLHDQLERGPQTLREISFAQTFGRDLSEAREWCRHYESSQDVNDINQAWELYYHVFRRIGRQLPQMTSLELAYCSPQLLASKDLDLAVPGTYKSGQPIVRIISFEPTVSVINSKQRPRKLIMNGSDGSTYAFVLKGHEDIRQDERCMQLFGLCNTLLAHDSECYKRHLGIQRYPAIPLSQNSGLLGWVPNSDTLHVLIREYRDTRKILTNIEHRIMVQMAPDYETLTLMQKVEVFGYALDNTTGQDLYRVLWLKSKSSEAWLERRTNYTRSLGVMSIVGYILGLGDRHPSNFMLDRVTGKIIHIDFGDCFEVACKRDKYPEQVPFRLTRMLTYAMEVSNIEGSFRITCEQVMRVLRDNKESVMAVLEAFIHDPLLSWGLTNVASPTGPDFRNADREHAMEANPGAPRARRPSILAANQPPSEFLAGQIDGSVTGGPPGVRPRARTNSSAVNGHTENIETEARNARAVEVLGRVSQKLNGRDFKPDEELEPVTQVNKLIIQATRLENLCQHYIGWCPFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUP6</accession>
    <name>A0ABR1UUP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661237.1">
        <property type="nucleotide sequence ID" value="XM_066819049.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052109"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8062638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="115" mass="13329" checksum="89FEC49B5BACE08B" modified="2025-10-08" version="1">MSTPTFLSARQEWKRHCVAMEERYRKERDKLDTWKKNELSALSAGSALRMSDDQRRLAMDKVTADHTKSMADLEARRRREAQDYLRSLTYPDPQQDQQQPPTSDPRASVDSKDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UUR3</accession>
    <name>A0ABR1UUR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_014761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661263.1">
        <property type="nucleotide sequence ID" value="XM_066819075.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052135"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF77">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8062664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="341" mass="38904" checksum="34145B5C4F9777D0" modified="2025-10-08" version="1">MPDYTSSFSKVYTQMTINFLLSRMDLDIFGDLFDPEPYIVDGMITPHKDPRLPTWVPDFREVHGKRSLDGANWKESGDKDYWRMMFEASSKSIVPNDKKLSRQRAFRASLDIPPPSSYNFSPDLKVFSLDGIMVDTVSDVSPHWPKIDDVSRRRCLYEWKDMFLTGNRDKDYPHGGLKCAEAFWRTVLCNIYWPDHSADEPFPELPARVDGRFDIPPAIGTEEQGLIDFICTWPSETVCQLPWRKMFVTTSGLLGLGPPSTSVGDMVAVLMGGRFPIILRQSKDKFEYDTSKSDKTYHRVIGERYVQKHQYLLTGISVENGDADHFGVSVTSTGLCKGRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVF8</accession>
    <name>A0ABR1UVF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_014974</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the secreted LysM effector family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8062877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661476.1">
        <property type="nucleotide sequence ID" value="XM_066819288.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052348"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF18">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046459564" description="LysM domain-containing protein" evidence="5">
        <location>
            <begin position="19"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="115"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="196"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8062877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="244" mass="25589" checksum="0DBCC266AE3CEFCE" modified="2025-10-08" version="1">MQLTHMLAAGLVPSLVSAAVECDFATSADSGATCASFASSWGLSVKDLKDLNPGISCPGLDASKSYCVIGTVTDAPPATTAAPTTTFKTTTKAPAPTSEPSNSPKMPGLAGNCDRFHKVSSGDSCDAIAKKNSISTAQFKSWNSQIDDKCSNLWLDYYVCVHVPGAATTTEAPSQPTKAPSGPTPQMPGIVDNCKSYHQVKSGDSCWSIYTDAGITLSQFRSYNKQVDANCSNLWLGYYVCTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1UVV9</accession>
    <name>A0ABR1UVV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_015139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000010">
        <property type="protein sequence ID" value="KAK8063042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661641.1">
        <property type="nucleotide sequence ID" value="XM_066819453.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92052513"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8063042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="113" mass="12076" checksum="8A10476C4DE61AA4" modified="2025-10-08" version="1">MLKKFKEDESSAAPIEGQQYVNLSWTRPGFWYRVISKLPPESRMIVWDELQKHNGGAADAPGSPDYAQQLAGPGRPPAPAMNVSTFSTNGMGGQAPLPPGMIQPGLDDVGLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1E1</accession>
    <name>A0ABR1V1E1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8064973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661727.1">
        <property type="nucleotide sequence ID" value="XM_066816035.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049095"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8064973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="138" mass="15627" checksum="A9404F5713F03D90" modified="2025-10-08" version="1">MKADRFTRGNMLPPSEAGFTGSRYSGDQAIPRNLLLAYKHIFGIYESNKNQGKNKYTETAHLKSPLADKINLLVREIRKFSHMRHQYILVLSTQQAIDNLIEAMQDGAADNKLAVTILEGIYGQTRTRKYRVAAPVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1Q7</accession>
    <name>A0ABR1V1Q7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661886.1">
        <property type="nucleotide sequence ID" value="XM_066816194.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049254"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="122" mass="13183" checksum="8FEB6E30C7302C02" modified="2025-10-08" version="1">MQLPRVSPSRPSSGAAEPLPQQSAATTKPEPQQAETSTSDVAAPETGSLHDPENFQHIAVFADALFRSLPPDLGLAGFDSIAPALERSIKNHSFTVACDGKDDPLTEATCRRLGYLVYRHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V1R3</accession>
    <name>A0ABR1V1R3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ZN622/Rei1/Reh1 zinc finger C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661885.1">
        <property type="nucleotide sequence ID" value="XM_066816193.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049253"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZN622/Rei1/Reh1 zinc finger C2H2-type" evidence="2">
        <location>
            <begin position="29"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="297" mass="33542" checksum="A4243F2FB48118F6" modified="2025-10-08" version="1">MSLSSSPEPNSTVLTDSFHAAMRPFTPGQCLFCPNSSPSFSDSTTHMQRSHGLFIPYQESLIVDLETLFKYLHLVISEDRECIQCGTTRATVQAVQQHMTGKGHCRFDVSQDSEFAEFYDFSEPEDEDEDEDAEEEGNQEETPATAISSHLKPTFADEDSIRLPSGRIISRQSSPGQTNPSFTQQFRRRTRKPLASQLEYSQAEPEEAGKGSGSDSDTQRNTTNTKALSKRENRERAAVTYQLASMSASDRNTLIHLPAHQEKVQKEEKRRRTKVDRKGNKNLYAYWHTETPVYTCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V2G1</accession>
    <name>A0ABR1V2G1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662125.1">
        <property type="nucleotide sequence ID" value="XM_066816433.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049493"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="62"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="656" mass="71940" checksum="CE9C59C5C8478AC3" modified="2025-10-08" version="1">MKFTVMKLFRRSKKSKGKIDNHDFNYDRDQRYPDSYRDSKPVNGHNEYYNGSQAYPSGSAPWLDLPVPVLERIFTFVCPHSQDESYENCEQSALEDACMLCDQRDLAHAGMVCKQWRKAAIPVLYHSIRIDSVHYCEREVFLSDKRKRNSSRWDRNGVPEDTAGARLTLLCRTLRDDPTRLGKRVNFLKIPYMLRESRSSHLARTIAVLPNLRYVDLPDGFFEDEPAYTTLKFEVQARCPDLRKMTFKAGSERSLEALSKGDIWPNLEVLELVKISVDPAALRHVLSVLPKLRALKITDSYVVDDDIFHDNDVLPAFPALIELDLVETPRVTSAGLAAYLSRRDAQMRLKVLSIISTGVRPQNLQEFLANAPRLQALTVVTEVESAFPSANSPVPPIANFSLETLRYEITASPKMSAYIGLTHGYYNYLAQSLFAGGLPRLSALYVRDLGFPDTMAGLPPPMPSFAGSGGRPSSSSSMKMTPSPFAAPNQNRFSSNNPFASAAASNPFAGAGHGGLGPPVLNLNQTLEIYTKGDKDDIDWSIVKMDPIDAPGYGGGGRRGHARNGSTASTKRPLSSYGLADAGAAWREGAAGARRSVVMANGTGGFLAVPSSPEAPPGRRSGSGLRNGSIGSGGGSDEWPRPMSSSGGKGDRDLWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V387</accession>
    <name>A0ABR1V387_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G-protein coupled receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_012400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662406.1">
        <property type="nucleotide sequence ID" value="XM_066816714.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049774"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022343">
        <property type="entry name" value="GCR1-cAMP_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF22">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05462">
        <property type="entry name" value="Dicty_CAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02001">
        <property type="entry name" value="GCR1CAMPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="13"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="266"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8065653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="453" mass="50981" checksum="F3E2E6D125D4D005" modified="2025-10-08" version="1">MANDSDTLSEGKLDAITIIERTGSVFSLLGCIFIIISFSCSKAFHKPINRLVFYASFGNMMSNIGTLMARSYVNDIDVFGCQFQAFLIQMFIPADALWTLAMAINVYLTFYFKFDAMRLRSIEIWYFLACYGIPFIPALTYIFISSKDDIRLYGNATLWCWISNTWDVFRIATFYGPIWLVISITVFIYLRAGGEIYKKRKLLRNFSSSATQHPEPLTMDDPFSTKTTEVTVTLEDSLETIGLATFGNGKSEVSHATPAAYSVTITSDHNKRHSQREPTSSPEQSSQANARTAAPITRHGAGAAQKRRVNFEINSATWSYAKCALLFFTAMLVTWIPSSANRLYSLVHPGETSYPLEIMSAIVLPLQGFWNALIYVVTSWSGCKMFFSDVFRRSGRSKPNDFASEFHDRRKGAFKRSARNIHMSGAESESMTELAYDSRPTSNEETKRGISIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3F8</accession>
    <name>A0ABR1V3F8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_012463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662469.1">
        <property type="nucleotide sequence ID" value="XM_066816777.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049837"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619:SF3">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK8065716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="611" mass="68222" checksum="4D34395C5CE10A7B" modified="2025-10-08" version="1">MATEPHPEVPEFVVVGLDGRRHPAFNATPRSGVIFQSALITGPGVQSVETVDSEPDHNELYAPCFKAAHELIATANKYSKKRSLKLLGIADVHTWDEVDAAMLAACDSLERIATKDRDTSGFTGKVKSAFRALCQRANIGLNFTNLVPQDFPGGSVLCGGLKMVFTALQSTSSYQDDVYRAIEDLPFTINDHAAYIRLDKQDEDLHRRNAALCTALFQLLECILSWFAKNPVATSMKMLVQPQGLAEALKMKQANVQRAASRFEKHALWLQNQRHNDSIELQHWMAYELFRTREDVSVIRARCEVLESFIQFLQQAHRSQTLAGFLDTESPRARKGMRRRSAAELRESFLRDVEYEPTAIERDINHILRLRTGSRQELDEDRVVELHNHPQFQSWLSVDESSVLFIQGNSDTPQCKEVAFVAAQVADIGKRMHVEPTEPAVRVVALAFFCSEHAASRRDRLGHPNALIWMLLLQLVDCYQEFSGSKLEKGLAMIADGETEKVCAAFESLIGHLPSNVIVVMVVEGVDSFLHLSIRRELMEIIGFLARLPAGSLGNCKLKILCTSAVSSDLLEDLFHEEQILRLPRTSRATSGLRNTEALAGLSGIATSREC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V3G8</accession>
    <name>A0ABR1V3G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein transport protein SEC23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_012455</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasmic vesicle</location>
            <location evidence="4">COPII-coated vesicle membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SEC23/SEC24 family. SEC23 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662461.1">
        <property type="nucleotide sequence ID" value="XM_066816769.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049829"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01478">
        <property type="entry name" value="Sec23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037364">
        <property type="entry name" value="Sec23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141:SF0">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="3 4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="6">
        <location>
            <begin position="77"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="8">
        <location>
            <begin position="354"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="7">
        <location>
            <begin position="472"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="5">
        <location>
            <begin position="587"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8065708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="666" mass="74543" checksum="EE111E105529B43F" modified="2025-10-08" version="1">MDYEALKEQWSEVEDRDGVRLSWNVFPSSRMEASRLVVPIGALYTPLKEKPETPLLQFEPVTCKQPCRAVLNPFWYPPIFLLVVDTCQEDDSLAALKESLIMSLSLLPENALVGLITYGTMAQVHEIGYTECAKSYVFRGSKDYSAKQVQEMLGLISPALRPGMPQQQPGRPLMPMGPASRFLLPVQQCEFQLTKALEQLQKDPWPVASDRRNLRCSGVALSVAVGLLESSFQNAGGRIMLFAGGPATEGPGMVVGPELREPIRSHHDIDRDNIKYYKKALKFYDNLAKRTAHNGHIIDIFAGCLDQVGLLEMKGLCNSTGGHMILTDSFTSSMFKQSFIRIFEKDANGNLLMGFNAVLEVLTTKELKVTGLIGHAVSLNKKSTSVGETECGIGNTCSWKMCGIDPTASYGVYFEIASQGGPTQHQQGQQKGMMQFLTYYQHSSGQFHLRVTTVARNLSGPAGDPAIAQSFDQEAAAVLMSRIAVFKAEVDDGPDVLRWVDRMLIRLCSRFADYRKDDPSSFRLEKNFTLYPQFMFHLRRSQFLQVFNNSPDETAFYRHVLNHEDVSNSLVMIQPTLDSYTFDQEGGQPVLLDSTSIQPTHILLLDTFFHILIFHGETVAEWRKAGYQDQEGYENFAALLEQPKEDARVRLTISTGNLTRLRLTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V460</accession>
    <name>A0ABR1V460_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polyketide synthase PksD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_011807</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661814.1">
        <property type="nucleotide sequence ID" value="XM_066816122.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049182"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050444">
        <property type="entry name" value="Polyketide_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45681:SF6">
        <property type="entry name" value="POLYKETIDE SYNTHASE 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45681">
        <property type="entry name" value="POLYKETIDE SYNTHASE 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="695"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoreductase" evidence="3">
        <location>
            <begin position="1004"/>
            <end position="1182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8065060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="1331" mass="144668" checksum="9A4F003DE9515EC1" modified="2025-10-08" version="1">MKYGNSFQLLREIGWDGGNLAIGQIASSPEHRKTSSLLHPAVLDNALQILLVQATKGATDSHPACVLAERKPTPGLSNEASVSVVGGNGKVLCNFGHVTMAPISSSQRDNAAGKSALLYGIDWKPHLCLMDRENMRQACDASAFTRDEAAMARFRKVLEPTLNLVLGNVLQDLSDTEREGVPEHLRCQVRWMDHHIAQLHGANNAASYGQLPTEMVQALLARLVDMYPSWEIFPAIAKDLRAILLGEVDPLGVAFDDRGLAEKFYADIFNTICDDRFHRLFDLISHENPTMRVLEVGAGTGGMTEHVLSTLGGLEDKQGGNRFSEYTYTDISPSFFEGAQQKFRAYDDRMSFIPFDLDRRPLDQGLEEGSYDLIVAGCVLHATKELNVTLGNLRRLLKPQGRLVLLEVVAPRNVTTNFAFGVLPGWWSAAEEFRVLSPTLAEHQWDQVLRDNGFTGNDLALQDYSCQDYHTFSLLVTSRKEPTHNGLSERGRLYLVLRCLSDEKALQLARAVQTLLAHYDSEVVPLHQAKTVSFRELDYVIVLVELDTPVLSTLSDTTYADIKDVIKRAHRILWTASAAVSNPRFAEFGLMRGFLRTIRSENLDKQIVTLSIEDGDIHHAAPGALARHLANVFSCAFETKSRELEYRLRDGELSSARLVARKELNGRLAALLAPQVRDGAWKPGPPVKLAVGRPGFLDGLEFVADPAAGEALGPREVEIEARAWGLNFRDVVVALGRLPGDDLGYDCAGVVTRVGPGCGTGLRVGDRVCGGSIGAMRSHPRAHMASFVKMPDSLSFAAAASIFTPAVTAYYSLMEVARLQKGEKILVHSAAGATGQMAIQIARIAGADIYATVGMDEKKQYLVDRFGIPADHIFYSRDNSFARGIMRVTKGSGVDVLLNSLSGDGMRASWECMAPFGRFIEIGKADIVANSGLPMENFARNVTFSAVDLHFMGEKHMGRCQELFPFRHLQSGKSTGRIVISVSDTDTVRKRLAVPVSWQFDPEASYVIAGGTGGIGRAIAAWMADRGARHLILLSRNGDAAPAAAKAMAELRARGVNVTAPRCDVSSSESLASVLDQCRGTMPAVKGCVQSAMALQDASFDEMTHAQWETTVRSKVQASWNLHEQLPATLDFFVLLSSLAGIYGSISQANYAAGCAYQDALARHRTWQGLKAVSLDLGWLRTIGVVAENAAYQRARQFSNDMEAIEAGELMALLEIYCDPKCPVLPPAESQLLVGAVTPANCLSRGQPPPILALRPLFSSFSLAGGARSSTAPGDGGASVDHALLFRRAAGLEERSEILVRGLASKLARAMSIAAEDVVPAKQLSDYGVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V4W0</accession>
    <name>A0ABR1V4W0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ASX DEUBAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_012047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662054.1">
        <property type="nucleotide sequence ID" value="XM_066816362.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049422"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028020">
        <property type="entry name" value="ASX_DEUBAD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13919">
        <property type="entry name" value="ASXH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ASX DEUBAD" evidence="2">
        <location>
            <begin position="17"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8065300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="321" mass="35214" checksum="4C6365B2BC80AA5E" modified="2025-10-08" version="1">MPSRRQAPAPAPAPAAKQDNDKMDEQIDDILDPKSAIGKADNVHRAVANPYYWSLLSDEDRSKILKLWPDQKAVINAGTPKAVLDFDCIKVNRDLRVNCRQYSEDHAAGRHDPDWLASAERAHVNRGEGLYDEMREDYVERQFGVPAMRKESKGKGRADSKSPEGEKEQQPQQQNGGGEISASAVGQQESPAPEIVVTQHADKDDQTVAEEKPDSKQVEDKTIVQPKGDEHEATEQQGSTAQQEPIVQQEVAVQEVVTTERAKVESEQTAATAEAANTESDNGKKAEGDSPETSPSTRSGVLRRSKRQNSRSNPISRASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V505</accession>
    <name>A0ABR1V505_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein cwh43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_013026</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663032.1">
        <property type="nucleotide sequence ID" value="XM_066817340.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050400"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057315">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051916">
        <property type="entry name" value="GPI-anchor_lipid_remodeler"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053912">
        <property type="entry name" value="PGAP2IP_TM_1nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053911">
        <property type="entry name" value="PGAP2IP_TM_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859">
        <property type="entry name" value="CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859:SF1">
        <property type="entry name" value="PGAP2-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23022">
        <property type="entry name" value="6TM_1st_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23021">
        <property type="entry name" value="6TM_2nd_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23226">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="493"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="522"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="544"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="574"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="609"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="647"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="2">
        <location>
            <begin position="19"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP first transmembrane" evidence="4">
        <location>
            <begin position="284"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP second transmembrane" evidence="3">
        <location>
            <begin position="453"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP C-terminal nuclease-like" evidence="5">
        <location>
            <begin position="680"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="966" mass="108634" checksum="67FE62EFB8AB3650" modified="2025-10-08" version="1">MVSSTYKDKPSGALFAFSAKWVSYAHTIVAYTAFISALVVGISLHYHKIVKNEFYGYPQEWFPSVSATIGDRYPERSFFQLFIALTSGPRFALVGLWYLLTAKPGKVLPKFVAGVGLFRTFTCGGWTYVTSTDDHDWHDIFMISYLVATLPWTLGCIALSPANPKAIKYRNYIASAFFGTLIPLVYYFIQHKVHRVAGAYTTYAFFEWSLILYDVAFDAVTVLDFSTFEIVVRDVGGLSQGVNKSGMSDVALEEQKTKATGGIFNIKFTWRETFDTIAEVYHGYVFWSILTGLGLVIWYFPLWFMGISGYEALVMSTISPLLLSIKPVRSFVTNHLRICHFLSLAGLLAYRVESPIYRLFTVGFGVSMSCLSWSAQLYSENVHETRLESKILAWLVGLVLSSAAKFAWWTNNPVWPIMHAENGGQNEIGLLLALIAAWRTIEYRGRKEREPGGSAFLSALGVAGLFFGLHSLLSDSSTMISWVWEGYPVRGPLAVPHGWFTIAAMTAGLLTGLAYPSLVSTWSVYGIACVGAAILTLYANWFGYYGGIVLAFYLMAIAGPFLKNAAKRSPATTFGLGFFLYNIMVLFHVWVVAYAFVPGGPYVREHTDWVMITMMLLIGAGVFNLTCTSSRGPQTPQRPNSSQHQRYHTSALALINLFFLAMAYLRFPTNDYVPYHADSQIITAGIWTIHFSLDNDMWSSEKRIRNLLKELEVDVVGLLESDLQRIIMGNRDTTQFLAQDLGMYVDYGPGPNKHTWGAALLSKFPIVNSTHHLLPSPVGELAPMIQATLDCYGELVDVFVFHSGQEEDAEDRRLQSEYASKLMGNSPRPSILLSYLVTQPQQGNYKTYVSDLSGMHDVEPGDWDRWCEYILYKRLQRVAYARVSRSTITDTELQVAKFVVPRSQEEKALVSILETNELARDWKVQKDKVPVGWRFPALFRGKGVRGHCYHVFDEPYYYSPKELGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V544</accession>
    <name>A0ABR1V544_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dipeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_013063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C69 family. Secernin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663069.1">
        <property type="nucleotide sequence ID" value="XM_066817377.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050437"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.60.10">
        <property type="entry name" value="Penicillin V Acylase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005322">
        <property type="entry name" value="Peptidase_C69"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994:SF17">
        <property type="entry name" value="LD30995P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994">
        <property type="entry name" value="SECERNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03577">
        <property type="entry name" value="Peptidase_C69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047092936" description="Dipeptidase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8066316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="29290" checksum="726502BF92491B7E" modified="2025-10-08" version="1">MVNLICALISTGLLVTGPAHASYAFYVGKDLTADGVVMIFPAADHASNATITVGVTQDAVKPGRLIQIPQVAHTSRYVSMEYSDFEGFPAPLTNGGVNERGVAVRDVWADSRDELYDMTPDPQTGLQYSDLARIVLERAATAREGVEIIGRLIDEYGEATYGGNSHLIADKDEGWVVWEFAGGQKLWAAERLGPDQVRVLYPGYIEDFPVNFTGSRDYMGSAHLVDFAAERGWWDPKSGAPFNIFKAYGKQGDNYTARDGGFKYMSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V556</accession>
    <name>A0ABR1V556_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD/NAD(P)-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066661887.1">
        <property type="nucleotide sequence ID" value="XM_066816195.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92049255"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053212">
        <property type="entry name" value="DHP_3-monooxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054707">
        <property type="entry name" value="DhpH_subs-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47469">
        <property type="entry name" value="MONOOXYGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47469:SF2">
        <property type="entry name" value="OS06G0597600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22607">
        <property type="entry name" value="FAD_binding-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="20"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="2,6-dihydroxypyridine 3-monooxygenase substrate binding" evidence="6">
        <location>
            <begin position="199"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8065133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="434" mass="48197" checksum="EDA3058E6FFD89C4" modified="2025-10-08" version="1">MAQENEQPDPKVADGKKHFFIVGGSLGGLAAGLVLRQLGHDTTILERNPTPVLEHQGAGIVAGGDTLAFFKKHNRCDRRIAVTSHRRQYLDKDGNVIHKEDMDQNMTSWDLAYYLMRANYDGVENAYCMVPDAKPTDGKAVHLHDRTVTDIQARDDGVEVSWTSSRGEAGRVQADVLIGADGPSSTVRTLLAPEVQRVYAGYCALRGTRDVSDAARESFCERFTFFHAPGVQILAYLIPGPDGAVEPGKRLINFVYYTNFPEGSTELKELMTDKHGKRRRITMPPGLTAPAAWEKQRKIARERLPPQFAEIVCATRKPFVQAVTDVISPTNEFLDGKVVLIGDALAGFRPHTVASTSQAAFDAMVLGDYVSGKVSREEWKRQTLGFARFIQKRGVDMGNRSQFEDLPLEEHIRDRNAASVPREEEVYPEWATAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V5T3</accession>
    <name>A0ABR1V5T3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_013316</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663322.1">
        <property type="nucleotide sequence ID" value="XM_066817630.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050690"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8066569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="422" mass="48453" checksum="791BEAF807AD50D0" modified="2025-10-08" version="1">MSSKLTSSMSAERCLSISDITIMYWAQQQQEPETIGCTQPALRRQLKSQEFHEDTLHDSCWFSRDSSMCILFASASRMRGCERCRHTLQKTFGIPDLWWTDHCKSSNGYFGCEVKRDAAGLLSINTWAYFEMKLVGQAAQYEWLKVNIFTHWVASSNQLSVLVFDAHPSLSERIATSFPPLETEYRRDPFWAYTKLMDEVVRIEDVAVMAIRDYVRAVEKEAPQEKPEPPYRFLHDISRHAVHVTETLDVAIETMDGMLSLHESVNAQVGNDDGWQTVHGHLLFSQQLLKGLRWRSKANERRLQNEIQLAFHMVTQYDSGVSVAIGKAAKEDSAAMKTVSMLTLAFLPATFISSIFSMSFFKFDTDTGWTVSNNFWIYWAWAVPTTLITSALWYYWQKQRVPGRSQTEEGRGRERQSLSLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V760</accession>
    <name>A0ABR1V760_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_013519</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663525.1">
        <property type="nucleotide sequence ID" value="XM_066817833.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050893"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="41"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="273"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8066772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="345" mass="38370" checksum="A6CADC2B7B935DF0" modified="2025-10-08" version="1" fragment="single">MSHSPTAVSSPPEYLDDESIDARILCWAVFPAVMAIVVVALRFYTRHCIIGKIEIEDWFALGALINSLGVSIGIGRRELPACFLPEALWYTALFYHVSLGLVKASILLLYIRMFKSYDTLRRASWIVLAIVGVGMCGVLAVTFTTCVPLRRKWDKDVDGYCHPDWPWWAATGFQAGSDVVIFLMPLPTIYKLRLPQRQKLGLVAVFALGLFVCLVAILRIVWVSKTDDTDFTFSGKAVGEWSCIELNTAIVCASLMVLKPLYHKVHPRRTRLISEDDTPGSYEPPPHSWRSKDTANASSEPRLRICGPTTRTMSPTLPAKPFFIESVRAKAEKGVPIAQIGSPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V769</accession>
    <name>A0ABR1V769_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase family 39 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8065899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662652.1">
        <property type="nucleotide sequence ID" value="XM_066816960.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050020"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046341740" description="Glycoside hydrolase family 39 protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8065899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="465" mass="52107" checksum="2B19E9E5E16DACD0" modified="2025-10-08" version="1">MQLILSLTTLATCAIAGSVLPRDSNTAVVDLAVTRGSPKHWASGFIYGIPDNEDQVAQHWYEDIGFRWGRTGGAQYGAPKRGWNWGRTEYQGRLQSTLSNYRSMRKVGAECIIYPHDIWGTDSLNSSSYWPGDNGNWQPYEAFVKALMDDLVSNNALEGLVWDIWNEPDIEVFWKRDTQRWIDLYIRTHNILRTDSRFANVPITGPSLAWRPMSSNKWWTSWLQAIADAGTVPDQYSYHLEGDLNAQDNDPQYTNQSLGALLRQHGLPERQVNINEYAAFNEMVPSGYAWWISRLERFDWIGLLGNWQGGTTLHDLFANLLTKSRNPRDYGASDYAAAPGYHVYRYYARNMTGVRVGTTGSEDAQFDAYATLGEDRVRVLAGPKVRSGQWKVQVEGLAAAGYADASGSVDVESWEFQGSNAFAVTGPPAYKGVKTYQYSSGSVIIPVSQTNNYTAHAFEIAVKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7B5</accession>
    <name>A0ABR1V7B5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_012902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066662908.1">
        <property type="nucleotide sequence ID" value="XM_066817216.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050276"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="249" mass="27151" checksum="24E63B0D5932DF2C" modified="2025-10-08" version="1">MAVPTSDDEPDHGTAPAQVDDPDHTIFGALSGPCLLCGRPSTYTCPFKADTFQCEFLCGWPVPRDIRARLRRIKEEEERQDAEFWGYEADDENEAGKNNANAQDSNDAAAETEVVSGVVPVGGHTTNDAKGGCVSSDADDIDVYGEMHETLFPKEVPRRPVQSKESRGGTATKNIGDGEVKIATSGKRKSKGGHNEENNKDRPAKKQKTAGGTSMTTSKEPAKCTKVKDRHAVPERKSRLGFPDWMSWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V7T5</accession>
    <name>A0ABR1V7T5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ecp2 effector protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664009.1">
        <property type="nucleotide sequence ID" value="XM_066818317.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051377"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046853126" description="Ecp2 effector protein domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="19015" checksum="C3EE4CA030258884" modified="2025-10-08" version="1">MRLIVTTQATLTGLSLASALSGDTITHLDQKHNGKAYGIEDCPRSICKNTNTKLCDDLHTVNLPWVLPIYMSDEPARWSDCEKLLDGIKGHPPKRLFLDGEKYDAGGKDYTRIAGSDQCAIGFKASDGTPSNSFLALSAADAEFLFRAAKKDDGGKGEDEGRLYSMGNVAATLLTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V885</accession>
    <name>A0ABR1V885_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_014152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664158.1">
        <property type="nucleotide sequence ID" value="XM_066818466.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051526"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8067405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="103" mass="11631" checksum="1D9EAB54ABAE2ECD" modified="2025-10-08" version="1">MWFTVNLLDSIAGLTLPNIDEASSPTQVYAARLMQLKQWVGSPGSKANPHRSGQSKWHRKVSEKREFLTTVRKARAEFWTKLVDEAHQEHQLAKAPPQPKIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1V970</accession>
    <name>A0ABR1V970_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_013351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8066604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663357.1">
        <property type="nucleotide sequence ID" value="XM_066817665.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92050725"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43812">
        <property type="entry name" value="BLR2425 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43812:SF2">
        <property type="entry name" value="FLAVIN REDUCTASE LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="1">
        <location>
            <begin position="19"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8066604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="227" mass="24866" checksum="03A60628A7DA7292" modified="2025-10-08" version="1">MFYEPGKTPHNLPFDPFKACVVPRPIGWISTVSPDGQSHNLAPYSQFNNLTFDPPYVMFSANQVSPTERKDTVRNAEATGKFGWSLATWALRDAVAATAEQVAYGVDEFARAGLEKVFSTALPGEPVPLVAASPVRFECVYHTTLRLPGNPPVGTVDVVIGRVVGVHISEDVLTDGRLDVRKTQPIARCGYYEYAVIRETFEMTVPGLSEALHAGWKEAPCALRSWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VA38</accession>
    <name>A0ABR1VA38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Stress-associated endoplasmic reticulum protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_013908</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Interacts with target proteins during translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation and facilitate correct glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the RAMP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000009">
        <property type="protein sequence ID" value="KAK8067161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066663914.1">
        <property type="nucleotide sequence ID" value="XM_066818222.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92051282"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010580">
        <property type="entry name" value="ER_stress-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06624">
        <property type="entry name" value="RAMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8067161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="70" mass="8193" checksum="A334C3F4C41627CA" modified="2025-10-08" version="1">MAQTPEQKRRNAKFAKEQEARRGKSETDIKKHEHKKVVSKAPISPIWLILLGFVIFGGLIFEVIQRIFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VH16</accession>
    <name>A0ABR1VH16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664339.1">
        <property type="nucleotide sequence ID" value="XM_066815049.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048109"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="78" mass="8247" checksum="C2BA8A50A4131DD1" modified="2025-10-08" version="1">MTPGKAKDSRPPSASLVISASEAFGTTSSRTSAPDSLGEHDGENDEYDNGGDEHGDEHDEVALPPSPFDFSRASDWPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHA7</accession>
    <name>A0ABR1VHA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664427.1">
        <property type="nucleotide sequence ID" value="XM_066815137.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048197"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="19"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="214" mass="25087" checksum="DBD1CE69E1D8B78F" modified="2025-10-08" version="1">MHLLPVRPVRKDPQLADEFRPFPSLPPELRQEFWDMILDREKQDRKVVIFWYGVQPTKSLVSPLLFVNAESRSRALRRYPDALPVWRRHFRYRWGPKLEKGVPAGVAHISWSDDVVFRRLEMVSIQPDYNMRNDALRPWVPALNTWLYRNAERCYYMDRESQVRSVASCAKLHYQPASSDEAPQPCNVDQFFSEVTHFLPGTLWVGSTSAGRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VHL6</accession>
    <name>A0ABR1VHL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664180.1">
        <property type="nucleotide sequence ID" value="XM_066814890.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047950"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046773196" evidence="2">
        <location>
            <begin position="21"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8070372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="205" mass="21187" checksum="6716AA9FFB9E7B96" modified="2025-10-08" version="1">MLLLCLNLLMLTGRIGPVEGHPTSPDDEVNAIPLPLGPFDPHDLVTGPVVPAPDDGPRTRTPPFCNYAWPTVFARLDEVQACHDGLAALDDTPCPVPPPPSGSGGDGNSGPDPPATFGTGVFCRDQSGQSIVMGVTFKAAGTSSACRDVATGVQWILDNCPADNPEIAPSNLVAGQTAAWGNGDLIVVVQQGTYLNWTAPPGLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VIJ4</accession>
    <name>A0ABR1VIJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Digeranylgeranylglyceryl phosphate synthase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_011260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664865.1">
        <property type="nucleotide sequence ID" value="XM_066815575.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048635"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8071057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="321" mass="34046" checksum="EA9E7594F7F762DE" modified="2025-10-08" version="1">MKPPFPSLTATWRDDIHPAIEYTSGDVTHHGETIVITGVGSGLSRETAIVFATDGAKQLVLMGRAVATLNETASPASKVNDRLQASILEVDVTDGTTVAGAAAKIGIWNDLVHGAGSVNTPVPASQADTGEYGKDFLGTNKLVKAMSLFWLFTVDDVATFVVPNVVFGVCGGLSKPIATSGPSSASNFVFRLLQVVFFNWSTLLVFDLANQRLPDAVSEDALNKPWRPIPRGLVMSVQARRAMLLGMPLIAGANYLMGVGVETALLFVLTWLYNDLQGAMRTGSAATSSSRPHSTCTTADLSKWPAATAPSRTWGRPGPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJB1</accession>
    <name>A0ABR1VJB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="14">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PG997_011522</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="14"/>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665127.1">
        <property type="nucleotide sequence ID" value="XM_066815837.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048897"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047010893" description="glucan 1,3-beta-glucosidase" evidence="17">
        <location>
            <begin position="17"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="18">
        <location>
            <begin position="83"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK8071319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="410" mass="45521" checksum="9328F7D6E54CC2D4" modified="2025-10-08" version="1">MLGTLPIALLAATASAASISARADPLRPRWQPGSTPIRGVNLGSQFIVEPWMAGDAWRDMGCGSAPDEWTCVQTLGQEKADAAFKKHWGSWVTKNDISKISSLKLNTIRIPVGFWIKEDLVDRSNEHYPKGGLAYLDKIVGWASDAGLQIIIDLHGGPGSQSKDQSFTGHSTSNPGFYTPANFERANKFLEWMAERIHRTSAYRNVYALQVMNEPVHSGEFPSQAADMVKTFYPAAWSRIRNREKSLGVAAKDQLNIMFMGQSWGSGDPASNLPSDHSFMSTDDHKYYKWDPKFGDKSSRQDYLSAACSDNSHGKSVVGEWSLQVATDGGDDKNWSPKNNGENKELKKFYQQFWAAQAQAYEKAGGWVFWSWKCNWIGGFSEYRWCYEAAVDAGVIPKDATSAKSVSPCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJF3</accession>
    <name>A0ABR1VJF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_011220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664825.1">
        <property type="nucleotide sequence ID" value="XM_066815535.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048595"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8071017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="223" mass="24194" checksum="7D5953A8B99F9861" modified="2025-10-08" version="1">MQQQPNVGILRSSLSHPVARESSEASTPAGIAFAVLMQQGYWSNPLPARAYCDRTIKRNWRLRVRSGIGEMLDARCLTPVVPQPQRNPDRPGMGRVEVSLISSFMQEAHRNLEKTASALPNGGWLPSIIGRRTGKYEKIGTTSTSRGLWVSSEPSGPANPTIPTRDVVEFTHVLDRAQVGQVPTACPVPSTSICKTSGLDSANPRYIENAPSEGSDGLWDSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJS7</accession>
    <name>A0ABR1VJS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme E2-16 kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_011600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665205.1">
        <property type="nucleotide sequence ID" value="XM_066815915.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048975"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029498">
        <property type="entry name" value="HeLo_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14479">
        <property type="entry name" value="HeLo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="372"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="541"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8071397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="649" mass="72260" checksum="106A3785F89323BB" modified="2025-10-08" version="1">MAEVAGLALGVLGIAGLFTSCIENFDIVVRAKDFGDDFDHFCTRLSLERVRLALWGETLGLMPSWPDQKPQVPYNHAIDREDIQPSIVACLCQLLDLLTRADVITERYALDCTPLSTQAYSQEVTQTPRGMLVLRDSFQKFKERIRKNQKQKSVWKVTRWSIHDCAQFEALVDKVHKLLDGLESITNALGVLERQRERLLEEVDSESDAQSLSLLQDIGSSKSAPVVLRAVSETASIRLTILSGDSQSYFTAKTGQTGSNRRALSLRKKELISRASWEGDPSINQSEDAVVVGDVQMEEQQIDRLSISETPHVSPEYESSDLHDSVPQQQRWISALLASRPDVKHTPVFSPSDSHYGQAIDLFRASDEHKYGKISGLLANSGNIHRAAIPFISAVPIDDALDKILACIEGPPGTPYQGGIFWITVWIEEFQPPAMRFHTRIYHPNIDHTGKICADYAGWWQSAKMLNKDTGRSSLRHNLPWFSEHATNQYSLGALLVALCGLLASPNIEDPLVPEIAEKYVTDYDGYCSAARLYTHRYAGSSRPSEKDLSFSHPSHPTEDSPSCEAPDFDESKTKKVTSSIGCKYIEGSMHAVKAWVANGWDGLFKFCLSSLILPQPYQMLELIARALETPSMLRGASENSKKAYKASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VJY5</accession>
    <name>A0ABR1VJY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SesB protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_011400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8071197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665005.1">
        <property type="nucleotide sequence ID" value="XM_066815715.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048775"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8071197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="313" mass="35192" checksum="021B5A9B591F17CD" modified="2025-10-08" version="1">MRKLNLLPTPKSDTGRGSRSVFWPRDLLPTTVSNARVMTYGYDSHIRHRLGPERSRSTVYDIAWDFLVALEASRRSDPERPISLIAHSLGGIVVKEMLRKSSTCGQSHLRPVFSSMVGVVFFGTPHGGADPRSFLKTVAEHLLRATGFTVNQQIADTLLPSSERLRELRDEFAPMARQQGWAIHSFQEQTGVKALNGGKVVEDTSSYLNAPDLEVTEHIFQNHMEMCRFVGPHDPEYRKVAAAISRIMAKEGKAKTDPDHVTKPHVDSMALKAIMDSLRFDQDDARHQNIKSAHAKTCKWLLKSDTYSDWVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VLD5</accession>
    <name>A0ABR1VLD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000008">
        <property type="protein sequence ID" value="KAK8070668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066664476.1">
        <property type="nucleotide sequence ID" value="XM_066815186.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92048246"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8070668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="333" mass="37550" checksum="8122551960317CEE" modified="2025-10-08" version="1">MWSSKKQSPYTNQRPVLLPTPPPTHQKKPPHRPAPAPARQPAFFGAAIARQNDAVVTQFSTARVGAVFAHARTAHLPASRLVGPLRHPGVPRSPYVSDRVVEGSSASDSRCDPLVAPRPFVRTALVAPHYALRDARAAGAAGASEGRVRGLLVRDRVRDEERRRRKIRRLREVVEEEARKVREVREREEAEERRVGEQRRKMEEEMREQEREERERPVPVSVLVPAPAQAHTQLPQNPHHGAPTSKAKTKAKTVRFFPDPSLGMDIATGDPVPYRATDRRQYEARHHSSPQNNSNYLHHRAMRKQRAAALMQERVQRVQRNGGLSGTWRCSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VU75</accession>
    <name>A0ABR1VU75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_009040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665317.1">
        <property type="nucleotide sequence ID" value="XM_066813355.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046415"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF40">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8074377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="466" mass="51279" checksum="F55951BAF46E5308" modified="2025-10-08" version="1">MRRGSAERLCERGIRLNFIDTQTSSAQPLTSLPPGTQLVFHDESQAIASGYTVKSHDVNGKHVDVNHASSRAESATQTGVNPGESGPLVSTSGGSSAEEDTVTVSPQLALPSLYLITDHEESLLMEIFVTKVGPGLDCLVASKLFTNITPFYALDHPVLYSAIMACGERYLVPTGESMHYEKACEGLELELENPNRDQLVCLTASTLLQAYTTMGNRPNQSGVDRARAQTDKAEVDINDSGLAAACFLVKHSHVCARKSHRRHTTDLGFNKTHSHEDQWVRRMVSICASIAALNADFVVYTDKTDPDSSEGLLRRCEQYKTWCDDWAGNVPRSMMPLCYVPPDPSAQAPSHFPQIFLIKPSASVARLLYHASCLMLDRIQAASPTADAHEVQLRQTRHASDICGIASQAEDREFVYVATCCLSFAARFLVEPEANEEAFHILDRITHGTPWRPKRFRQGADCASRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUS5</accession>
    <name>A0ABR1VUS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">THIF-type NAD/FAD binding fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_009635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665912.1">
        <property type="nucleotide sequence ID" value="XM_066813950.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047010"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00755">
        <property type="entry name" value="YgdL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="1">
        <location>
            <begin position="109"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="1">
        <location>
            <begin position="165"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8074972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="494" mass="53963" checksum="C56C1EF5247AF722" modified="2025-10-08" version="1">MSSFLSQATSNTKVQFATTAVVSGAVVASAILGYQQLQRNERINKLKDSIPSLGAEGGDLGKLTNYGGATSTDKEDQRNEALARRAQAGDYDDELILEQLARNRVFLTPKLRKSFVVVVGCGGVGSHATATLSRSGVSKLRLVDFDQVTLSSSTDTPSLHWPMRLIAITPWTQFDLRQEKFWDQAADRLLAPWKETGQKPDYVIDAIDNIDTKVALLKYCHDHQIPVISAMGAGCKSDPTRITVGDIGNSTDDRLSRATRRRLKLLGITNGIPTVFSTEKTGDGKAELLPLPEGEFQKGSVGDLGPLPDFRARILPVLGTMPAVFGYTVANHVILSITGYPMDYLPARGREKMHDGMLAGLQSTEEKVVRYAAGGDPAVAVGLKIPINIGDVAFLTEEVYRGRSAITGLTNRLHLIRWRKPKSSTMIKIGDGENAQKSSNVKLGDLVCMTKDEALQHEKKVLKEGKEPEELYDAATIERVEAMLKDATAHEKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VUU6</accession>
    <name>A0ABR1VUU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beach-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PG997_009688</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665965.1">
        <property type="nucleotide sequence ID" value="XM_066814003.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047063"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06071">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01201">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1540.10">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056252">
        <property type="entry name" value="Alfy-like_Arm-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000409">
        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051944">
        <property type="entry name" value="BEACH_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023362">
        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46108">
        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46108:SF4">
        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23295">
        <property type="entry name" value="Arm_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14844">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01026">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81837">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50197">
        <property type="entry name" value="BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51783">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BEACH-type PH" evidence="6">
        <location>
            <begin position="1780"/>
            <end position="1913"/>
        </location>
    </feature>
    <feature type="domain" description="BEACH" evidence="5">
        <location>
            <begin position="1952"/>
            <end position="2244"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2377"/>
            <end position="2418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1095"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1741"/>
            <end position="1766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1749"/>
            <end position="1766"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK8075025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2562" mass="289058" checksum="85F9017491E4330B" modified="2025-10-08" version="1" fragment="single">QHVYPTKQIPFLHFGLDAFVRIQGTGSPTKAARFRSCRAIDPTRPIPRHTRTSGPAGSDQAASHRSETPSSVQDDFRHLHGFQRLFDILRAYSGFYNPQKRSQDEKESLFRLLDAVLGVLSVAFNAHPGNMRYFRTRVESGGWEALEQSIASIGLGGGDLDCWTSSQLFGKLFAFSLQIPTLGGFCQKTIFEDMPVMVGNDDLGEDAPKSEEGPDPEEQAALIQDAVRTVIGPATKLQYPEIIRTVVDFWISMPKGSESQSITVSLLVLRVITEVITASTHNLCLVHDTTVHSRLLAISFDKNAGLSRAEHNLVMNICRSLMSLGVKRLADAQALLMNSSPEASEHCLEMVQEHQDPPFIQFDLSLHGHASIDLPSLGRSFPPSSSNGYTFMAWIRVDEFDPKSHTTIFGVFDATQTCFLLLYLEKDTQNFILQTSVTSRRPSVRFKSFAFKEKRWYHIALVHRRKTMSANKAYLYVDGELVEHLQATFPSPPPLANGSTESFASFASSNNKTMPVQAFLGTPRELSSHLGAGIVTSKWSVATAHLFEEALSDDYLAVPSRLGPRYQGNFQDCLGAFQTYEASAHLGLRNDLVTPGKDGSDLIRVIRDKAGYVMPENRLLLSLMPSSIIRERDSFSDSQLFRSLSRGPSHALSQMTMKSGTGIAINTALPSINDALIRSSGVAVLSGEPVIAVPRHLDDAMWQLAGFTPLALKIVERASNAESLTRAVEMIFRCVNSSWRNSEAMERCNGYNIMGMLLKCKLGLAPTGAENITARLSLDDVEKDRLSFQLLSLVLEFVGYDHKNSLNSIIKNPLAYRILLVDFDVWRRCVPIVQELYYKQFITFARNSKYHEYNNRRLLRMRVVKRLLDALKAEPLAAAVLPFFMDALQELVQCSYNTEVHRSLALFITYAFHAAPASLPRTPKPSSATVARPSGTPTRPVIETNKAGYVLNTTLNRKQVGVKILKMYSDLLCQKGNLNYIRRFAKTVTNKRMTPRLLLVTHGSSYASKFSGKSGGFHIMAHRLKRWWDVPTIWPICFSILFGYDVAEIDFDKSFDFFSLLETFGQCKIAFPETLPIITSMLQIGLKDILRNQEDPASPRELGSPQGATTIDSNVFKGRPRGRSMSLAEELETRQTPQPSQVKVAGNAAVLQTVIRFLADIHSRSMNFKDFALSSDYVKLLLAALYPVIVSTDAVRPEIELESRDSALTFEGGDVMIRPITGTSAPAPIVRTSKAIDSVLQAPNDTVRGSPLRKASSFVLLTSQRPPQLSPARLTHVMSPKKNTNSQNTSHAVLEGIMELVVNVFLDQLFYRKEFPGFGLFIKVPPGFQEHQAYFESHVLRGTILHLSNTIKLDWKLLIEPRVLTNMARFSLHMVEAIFEGWFMNGADSMLDFLGFLLEYLNRPDVSKLKSVRLCSQAVSTIRTSFLKCVLLKLSEMDDPQCADTEAISSLNKILYWQMVILDSLSVDDDYTKLLWFQFYVKLVDTREAVSLATVNLWRIMLVQKPEESSAIFQQFTSTEKSDLVLEFEKLTELDTESFVAWVTEHRASLDQLFVNGLSRTWEDFVRLENSRTVETAQVRLAKRREVLKRWQLESSEKESAILRHDMTNSAWMKSIYGSEHFKHQRLLQDQQDDVLFHSSEFMRMSQDLTRPGAVLQQNSIIKWKLDRTEGRDRMRARLLPDTEPQKELFQPKRRNTDASSRGVPRLRFLVQAPMLPVQNHQMPWQVGSRRLRKVKDTLKPKGEQTVAPDEDFEMVDDPNDPEPDEAFEDKNRRVMRRLETGDLVQQVYNISRIVGLEVCEGILLVGKNALYIMDNYFQSAEGEIVNIWEAAPEDRDPFVQIITNDKTDTKGFSSRRRAQGSRSWRWQDVISVSKRRFLFRDVAIEIFFTDGRSYLLTTINPAVRDDIHLKLASKTPHTAGAATLPNPEDAWRLESLKIHEEPTQGLGAKFGGFFNSSPWNPSLRKWQRGEMSNFHYLMLVNTMAGRTFNDLTQYPVFPWILADYTSEELDLEDPATYRDLSKPMGAQTPSRRADAMERFNAAVEMEDQAPFHYGTHYSSAMVVASYLIRLPPFVQSHVTMQGGTFDHADRLFYSVERTWHSASRERGSDVRELIPEFFYLPDFLTNINGYDFGTRQGSGGKVNDVALPPWAKGDPKIFIAKHREALESPYVSQNLHSWIDLVFGYKQLGEAAVQNVNVFSPLSYRGAMDLDNAGADEREHATSVIYNFGQTPHQVFTKPHPGRENMKFPAKRLDTTSYALARIPHPLLESHERVASLIYSPKLDRLLCSSPFRLNLPRSLTSIWNGGYADHSIRFYFTENRKVAGVNENLHTGQISCIFVADSKTLVTAGEDCVVSVHSIQTAAGKPVELVNRSSLFGHKTPVTTIAASKAFSTLLTISMDGHAFLWDLNRLEFVRKLPNNRAVECARINDISGEIMLCSGPNVALYTVNGELLLDQNVCEEHDDFVQSCAFYEGSGSEWLESFLVFTGHKRGRVKIWQRTVKNGKWTLELIRRLDHADARSESRANTEAAITCITPMPQLVYTGDDDGRVYEWNLIHREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VVN6</accession>
    <name>A0ABR1VVN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PfkB family kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_009972</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666249.1">
        <property type="nucleotide sequence ID" value="XM_066814287.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047347"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052562">
        <property type="entry name" value="Ketohexokinase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774:SF3">
        <property type="entry name" value="KETOHEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774">
        <property type="entry name" value="PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="3">
        <location>
            <begin position="7"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8075309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="299" mass="32520" checksum="225278165F801A53" modified="2025-10-08" version="1">MKHFVGVGACYLDTILSIPHFVVEDEKLRASSIARRRGGNCPNTIEVLQQLIEQRAGAAELQANLVAVLPNRDAAAVNDIEASLGGQSVLRHCIYREDQVEPASSYIIRNTATSSRTIINYNALQEMTSAEFKDIADTLGNEAGRIPDVSLECMLYLRQQYPGVKISVELENPAREGLQELALHADVVFFSKSWALVSAESDYSAAASLLCCTWGEDGAWAYEPVSGMTHHAAAHHFGDDAVVDTIGAGDTFIAGILYGMLFHSQDWRCAERLRFANEIAGQKVLQEGFAGLGALMAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VWD3</accession>
    <name>A0ABR1VWD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CmcJ-like methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PG997_010212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666489.1">
        <property type="nucleotide sequence ID" value="XM_066814527.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047587"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK8075549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="30591" checksum="C037DEFA3FF66EB2" modified="2025-10-08" version="1">MADKVHAPLAFLRDLKIYEVEKPYHLTLTKDRECDSVITNIAHDVYGNIEVTNIRGSEDSFLLDVHGFQLAKHETSMSPRDFDSLEGRERYASEIESFLKALLGAKDVRMMHYKVRDRTSPTEQDAEKEDSIRGRPIPDASADGALRRIQLQWPLEAEELQKRRFQILNLWRPLKSPLRDWPMAFCDVRTVEAEDIVLADQISPGFQGENTLLYFNPKHRFYYVSEQKQDEVWVFKQFDSQENVAGGGCLAGFGNHNEVADHDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY34</accession>
    <name>A0ABR1VY34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_010420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666697.1">
        <property type="nucleotide sequence ID" value="XM_066814735.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047795"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8075757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="127" mass="13784" checksum="E6AE857898208829" modified="2025-10-08" version="1">MAKARASLNQQGTSKTLPYQPRLPYETTTRPGGAPAPRPATAAAAALPESLRAPRPRPVDPNSPAYKAASRKYVRTMIAMPILLVTSWVLFDRLARGAEVKTFKHSPSSDQQLAQARRRAMGAACEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VY38</accession>
    <name>A0ABR1VY38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kelch repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_009426</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8074763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066665703.1">
        <property type="nucleotide sequence ID" value="XM_066813741.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92046801"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="549"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="482"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="735"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="491"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8074763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="769" mass="84608" checksum="09DAF488D7D64762" modified="2025-10-08" version="1">MDQQPGSCQTSLFGGPPAPTPASAPSSTSTALALPPPQVPVPPSAVPSFSPMASNAGTPASVASSNNTFVMPNSPIKNRAMIDGSYRPKVTRTLGSRPACLVNASVTYCGNNHIYAFGGFDQYTDEVYNHVLKLDLISHQWSLVDNFGDIPGVRMGHTATLYQGDKLLVFGGENEHRTYLSDLIVFDLKTAHWMQPHVNGPVPKGRARHAAVLHEDKLFIIGGITGHDNYVLDDICYLDLKTYTWSKSWRFVSRFDHSAYIWGDRLWVFGGLSEDMDKTGDLWWLDLKGSPAFETSPHMGVSDRHSSIGRTTGSPRQPYSISSPTVIGASGYAANSRTAQVNTPSFQLKTYAPMAPGSISAMKFVSGANVPSQGAGRHFHIYSAGTLLDFVTPAATIAPKECSLSSLDLGALRWQKLAEGREIFKAGYDWHYCTMNEDGTKAWLLGCPKDNSGHDMVPAVSEEYLSDIVEIDLRRYGFLGNNAPEPRAESSRPSFQRSQEQPSKGLGSDLAKLFNRPPEEGSGTDFVITALAGDYEDDDMMSAGQFRASDVPADQNWLSPDAPTSPPIYVHKLILQARWPHFARMYNAQMAEFHTKKMHIPEPYSVVKAFLNYLYTDSIHADDGVTDLADVAGLLVMSNIYNIPHLRLLCVNRLAKELDVLHACIIWYCAGLANEEWLRKRAASFCLTNWGRIVRTQGFLRLPRSALVELSQEIDTEGRVIGGEELEYVDGSYGNRFDNSSMSRKDSMSSERTQALPSDMDDSEGMDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1VZF2</accession>
    <name>A0ABR1VZF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial hypoxia responsive domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_010374</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Associates with the respiratory chain complex III/complex IV supercomplex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RCF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000007">
        <property type="protein sequence ID" value="KAK8075711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666651.1">
        <property type="nucleotide sequence ID" value="XM_066814689.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92047749"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050355">
        <property type="entry name" value="RCF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297:SF3">
        <property type="entry name" value="HIG1 DOMAIN FAMILY MEMBER 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297">
        <property type="entry name" value="HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="HIG1" evidence="10">
        <location>
            <begin position="5"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="104"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8075711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="197" mass="21963" checksum="E32656E6C6B10C4A" modified="2025-10-08" version="1">MADKPMPSSFDDDREYQETGSQKVWRKLKEEPLVPLGTLLTCAALYNAWRGMRRGDHAQVQRMFRARIGAQAFTVCAIVAGGAYYGKDREKRQELIKLEAQQRAEERNAREEQQLQDHINRRRERRQQQAREGKTATSTAAASTPSGETTSDAEGQVPLEGKKEGSTVLGALSQSGSSWFGSGKKKEDTPSSSDEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7B3</accession>
    <name>A0ABR1W7B3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Isotrichodermin C-15 hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_007192</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666849.1">
        <property type="nucleotide sequence ID" value="XM_066811507.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044567"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF226">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8079374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="244" mass="27845" checksum="C6ED26336B377246" modified="2025-10-08" version="1">MHSYKRKIVSHAFSRRSIRSFEPALLCQVDIYLEQILLKSASQPVNMTEKLSYLAADIIGHLALGYDLSTQTSEENRLLPRSMTLSFFVGNISHHFPSFYRVHTNWVFDYIFYETREKFSRLLEKMVKSRLALDTHAAPDFFSFVADELPPDEAATTRDSVIWKEALVFLVAGADSVTTAMTAAFFYLSRNPACYQRLADEVRSTFASGHDIRDGPRLAGCRYLRACINESLRMSPPAPANLWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W7M1</accession>
    <name>A0ABR1W7M1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066666960.1">
        <property type="nucleotide sequence ID" value="XM_066811618.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044678"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="50"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8079485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="235" mass="26637" checksum="D14E91CAC888AC31" modified="2025-10-08" version="1">MFIPKGAFARAAASEPGGSLQPPIRTDDLGSAVIIVGAISVSITTIALALRLWARAQSNKWSFWWDDWILMVTTLFSHGFLALNMAWTRLGLGKHVENIDMASLLPTIYMSKASILMYAICIYLIKVSALLLYARVFNRSKRFRLVLRWLGGAVTAWFLCTALVPWFNCNPIRKTIDPFVPGVCFDRMDWFLASAFINAAIDLTILIMPLQQVWKLQMTTRRKIQVTLVFLLGYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W818</accession>
    <name>A0ABR1W818_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein-sorting-associated protein 36</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ESCRT-II complex subunit VPS36</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PG997_007375</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the VPS36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667032.1">
        <property type="nucleotide sequence ID" value="XM_066811690.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044750"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021648">
        <property type="entry name" value="GLUE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037855">
        <property type="entry name" value="Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031558">
        <property type="entry name" value="Vps36-NZF-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128:SF12">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16988">
        <property type="entry name" value="Vps36-NZF-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11605">
        <property type="entry name" value="Vps36_ESCRT-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51495">
        <property type="entry name" value="GLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0967">Endosome</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GLUE N-terminal" evidence="10">
        <location>
            <begin position="6"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="186"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="578"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK8079557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="646" mass="69650" checksum="D9A1FFF0FBB6EC8C" modified="2025-10-08" version="1">MFLKHIDLTTALRPSYLDGEALTFVQDNVGLYEGKYKLPNQQKGQVYLTTHRICYVDSQEPRKHSVALDLKDIERYEFYAGFLKSSAKVTLIPKPAKRASLQSRAAAAAFSPSSPSPHSSARASPAAPVQATSATWVCTICSFPNPVPSNFDPTTANVHTPLPPCLACGIKPALTHVLKASINNATSRQPAPGIPSRPQSGFSPLSRDRGPTVDGVGGSSPSGADFSPAASTPDLNTGAGSGFQCPRCTFENHPSLLSCEICGAPLISQEVSSSITPVTPRTDSPGPILATGNVTGLETPESVKISFRAGGEKIFYERLKVCMVQRKWLLHEAPPIPRANRAAEGDNGTLSRTGSGAGRTKTAGIAGLEQMGLDRRRNNELMIGTSFEDLEALMASAKEIVALAESFARQVNGGSDNATTEANALLAESASQLGLITTKDIVGGGSGSASESLYLSELSRNLAEFLTDDARGVLKKAGGVMSLVDLWAMFNRARGGVELVSPNDFEKAARLWEKLKLPVRLRTFKSGVMVAQSRDRTDEATVKALLSWLRDLHDIPPDSEVSWDWQEFGRGVTAQDVAERFSWSIAVAEEELEMAEERGVLCREEGIEGIKFWENYIDTGEYRKRSRRPVTENDRILADLKAAGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W904</accession>
    <name>A0ABR1W904_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">HIRAN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PG997_007781</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CBS 114990</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667438.1">
        <property type="nucleotide sequence ID" value="XM_066812096.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045156"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014905">
        <property type="entry name" value="HIRAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF11">
        <property type="entry name" value="FAMILY HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G06590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08797">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00910">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="324"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="652"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="729"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="701"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="701"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK8079963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="893" mass="99224" checksum="D927582C6DFFC212" modified="2025-10-08" version="1">MVRSKRSRPHDAGSSQPPQAKNPRLGASQNNGPRSSLPAGGSSQPPPATLSVYGEEEDPIDLTQDDPQSSLELYGSLENKIVGVRYYNGVATPHELVVLRREAHNQYDSNAIRVDNVMGNQIGHLPRTVVAKLAPYVDRGDLVLEAVLIGEKGYFDCPVRIYFYGTSDPVGRTKLEESLKADKLLKATQLKATRKEAEAVRKSTGLKSGTSSAGLGQEAIQREEQGATLQGLVSTSETFEVQRTDQLRNVLATGEEALENMPMAEQPEPLKSTLLPYQLQGLAWMIAKENPQVPAVKSTDVVQLWKRCSNNNSFQNLATSFVTNSPPQLLKGGILADAMGLGKTLQIISLILSQGLQDGPTLIVAPVTVLGNWEQQVKFHVKETHQPRVLLYHSSKQVSSADLKNSDIVITTYGKLLSESKVQNGAARLYSVNWRRVVLDEGHNIRNPSSQTAHAAHRLQATSRWLLTGTPIINGVKDFLSLLQFLKLKGGLEDEALFGQVISRPIRQLHDSHPDRSKAVKILAHLMKDICLRRRKDMKFVDLKLPPKAEYVHRITFSKTEQPKYDAVLAEARGELEKYQASATKNQQGRYSSILERLLRLRQICNHWMLCKERVQNLLAFFEDQKVVALDPKNVAILQQALQFIIESQEECAICYEEIGLHEPVITACKHVFGRACITKAIQMQGKCPMCRAELKEDSLVEPAPEHGEEAGVDPEEASKSSKTEALVNILQATLKKEGSKVVVFSQWTSYLNIVQQRLKDSNIPYTRIDGSMPKKARDASIESLNSDPNTRILLASLQVCSVGLNLVAADTVILADSWWAPAIEDQAVDRVHRLGQTRETTVWRLVVEGTIEERVLNIQTEKRRLVSEAFQEKSKKGKAKETRMADISKLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9B2</accession>
    <name>A0ABR1W9B2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospholipase</fullName>
            <ecNumber evidence="5">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_007825</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14445"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the phospholipase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667482.1">
        <property type="nucleotide sequence ID" value="XM_066812140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045200"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09138">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09141">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016555">
        <property type="entry name" value="PLipase_D_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF186">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00614">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009376">
        <property type="entry name" value="Phospholipase_D_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="7">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="7">
        <location>
            <begin position="636"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="552"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR009376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="870" mass="99138" checksum="DD3A32E7F42AB4EC" modified="2025-10-08" version="1">MDRLFHKLEEKVEQKFDEVFHREGHNHEEQQQQPHEENGHFTPQIQQQDEVRQSHRFQSFAPQSSGGVKWFVDGASYFFAVSVALEQARESIYILDWWLSPELYLRRPPSRNEQYRLDHMLRAAADRGVKVNIIVYKEVTQALTLDSAHTRHHLEGMHPNIKVFRHPDHIPSVNDAKADLEAEIQGLADRFNAAALHKISGDALKSLYGSAGDVVLYWAHHEKLCIIDRTIAFMGGLDMCFGRWDTNSHPIADAHPGNLDAIIFPGQDYNNARIFDFEGVNDWDHNKLDRTQSSRMGWSDISISLNGPIVHNLIDHFSDRWNFILEQKYNGKDPGKYEPVLSSTGGLTGSEDRGAPTEGSIRHRLTHGFQRYMGAEGGEGERELGEQHRGGSSELSIQLCRSCTEWSAGHPTEHSIANAYIAAIGNARHFVYIENQFFITATSDEQHPVENKIGRAIVDRIVRAHQSREDFRFIVLMPAVPAFAGDLKSDGALGTRGIMEFQYNSINRGGHSIMEALQQQGVEDPRQYITFYNLRNYDRINISSTMGRVENDSGVSYEGARREHDDMVGGYPYGGQSDGREGGSGRQYERYQEAANDAKDLTWDSISACYMNAGPDLHNVPWDGDEESELNAFVSEELYIHSKVLIADDRLVICGSANLNDRSQLGTHDSEIAVVIEGGETVESAMNGQPYQASKFATTLRRQLWRKHLGLLPHQPHDRPNANWTPIDRDPQMYDFDSPADRLVHDPMSREFWDLWTGTARSNTEIFNKVFHPVPSDHVRNWEQYDDFFSRHFIVPSNEEDMSEEEKRGRVPYGHVVREEFPGGVRELKDWLNRVRGTLVEMPLEFLIELGQDMAKEGMSLNKFTETVYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9C9</accession>
    <name>A0ABR1W9C9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiamine pyrophosphokinase</fullName>
            <ecNumber evidence="7">2.7.6.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PG997_007914</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>thiamine + ATP = thiamine diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11576"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18385"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the thiamine pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.2" evidence="7"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667571.1">
        <property type="nucleotide sequence ID" value="XM_066812229.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045289"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07995">
        <property type="entry name" value="TPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10240">
        <property type="entry name" value="Thiamin pyrophosphokinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006282">
        <property type="entry name" value="Thi_PPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016966">
        <property type="entry name" value="Thiamin_pyrophosphokinase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007373">
        <property type="entry name" value="Thiamin_PyroPKinase_B1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036371">
        <property type="entry name" value="TPK_B1-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007371">
        <property type="entry name" value="TPK_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036759">
        <property type="entry name" value="TPK_catalytic_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01378">
        <property type="entry name" value="thi_PPkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622:SF8">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04265">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04263">
        <property type="entry name" value="TPK_catalytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031057">
        <property type="entry name" value="Thiamin_pyrophosphokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00983">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63999">
        <property type="entry name" value="Thiamin pyrophosphokinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63862">
        <property type="entry name" value="Thiamin pyrophosphokinase, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamin pyrophosphokinase thiamin-binding" evidence="8">
        <location>
            <begin position="201"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR031057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK8080096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="294" mass="32557" checksum="35C44860F9CECA80" modified="2025-10-08" version="1">MAAEGPITDWFPARLFPSRPWETPTKEKDQLSVIILNQPLTDIQTLKRVWHNSSYRVAADGGANHLYDCCSQAISRKAEEQKPEEVLSDLDVIIGDLDSLTETSQSYFEEATGGKVQVILDRDQDSSDFTKALRHIRERRGGKGGESKSTDIVCMGGLGGRVDQGLSQLHHLYLFQTSPTYAEGRVYLVSGESLTFLLKAGTHRIHVRERERARAENGANGGDVFGKHVGIVPIREPSVISTKGLEWDVEDWPTEFGGQISTSNHVPPDTEVVEVRASKDVLFTIALKSWPAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1W9T9</accession>
    <name>A0ABR1W9T9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PG997_008005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667662.1">
        <property type="nucleotide sequence ID" value="XM_066812320.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045380"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056693">
        <property type="entry name" value="DUF7791"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25053">
        <property type="entry name" value="DUF7791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="255"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7791" evidence="4">
        <location>
            <begin position="569"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK8080187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="884" mass="100465" checksum="CE9A7BE12434D637" modified="2025-10-08" version="1">MEPLAVLGVAGNILQFLDFSQKLCHSFFEIWNSSHGITKANADTQSRMNTFIESADIVVADLQTYIKSLSCDRGNEADRMLHTTLDKCLKLANDLVTRVQTLALPRGAGKWKAARAVVKSLWKEKELLSLQQSLSTYRKDLEWFVLLSIRSSQVLSDSRQRDQFADLQSTVVSRLTDEIRTQFSQLPKWETVDASESVRGPGASRESSETTDETATMARSLASQLAEADRKILSSLEYLVMRDRESAISDAEAETFDWIFEDPATSNKPWDNFKQWLSSDTVPHLYWVNGKAGSGKSTLMKHLFHHLMTREALAVWADQSKLLMAGFFFSYSGSELQKSLEGLLRAMLFACLSENRELIPLAFPDLPQIGADLDSKYWSLERLEAATMRLISQVTLPVKFCFFVDGLDEYAGDHTHIVRFIKQVADYPNVKVCISSRPLLAFEKALENTSKLILQYLTITDMEKFVERHLGAHPRMDELEEQEPGLKRGLSLEISNKASGVFLWVTLVMGSLIEGFENYDDAPDLRRRLDDLPEGLESLYWHMVERVKPKWYLEEGFRLLLLTRAAGGSVHVLTLCFAEMEEDAMGVDTLSNSPSYQKQEELCRNMMGRMKSRCMGLLEVNPEDGCATFLHKSMMDFLETDEAIHAAARHIGPGYVPETRLMLGILRLLKTFITRLNGVSADDDEPMNLDDARLQRSHFFQSVLVVVHLFMELARRAERVTDTDNSDLVDELDSVTTKLWNRVAFRSKGERDGTIHWSQAREDPERSEGTYTVRSSLPTQTRIIPGPSAFVYFTYQQGLRLYPAAKGLLKRRRRRYTPIHNWAEFPGTPFASTCRLQAAEEIIGVHTDPGSYIRENDKPRFGRYYKDDEIGDHNFFVGSGSTWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WA13</accession>
    <name>A0ABR1WA13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PG997_008144</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CBS 114990</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667801.1">
        <property type="nucleotide sequence ID" value="XM_066812459.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045519"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="46"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK8080326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="261" mass="28989" checksum="9108DDEEF97D4D9B" modified="2025-10-08" version="1">MNSQVAKEYNEQSKSYDNYTTSTPYGDLEAQLFRLALGDDCSGLKVLDLGGGSGLKARAALDAGAARVDVVDISAAMMQSGQAATEASLGREGVGRIRWHEADVSKPLGHLPLQEEGTYDLVIAAWVFDHARDRAEYDGMWRNCAAYLKPGGRFLGVRMGDPRAPTLDGRYGVYMKDFEDTPDGVRYRYVIQLDPPLEFEASTLNVSMSGSYEVPEKYGITDFETEPPENAPIIRDDPLFWRPFLEKQGMVVFKGKKRLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAF5</accession>
    <name>A0ABR1WAF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Leucine carboxyl methyltransferase 1</fullName>
            <ecNumber evidence="3 8">2.1.1.233</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PG997_008291</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CBS 114990</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine = [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:48544"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="2.1.1.233"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. LCMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.233" evidence="3 8"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667948.1">
        <property type="nucleotide sequence ID" value="XM_066812606.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045666"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016651">
        <property type="entry name" value="LCMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600:SF21">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016305">
        <property type="entry name" value="LCM_mtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK8080473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="339" mass="37378" checksum="03B2BA32CB71A08B" modified="2025-10-08" version="1">MAAPSIPNLLSLRGSRGGGRGRGSRRGGPPGGSAASGPGHDTTIQGTDTDASVSRLSAVDMGYLDDPYAQYFVQNQMGPATRRLPIINRALDRLIDAFLSSELGPEAGRKQIVSLGAGTDTRCFRLFSRNNVTGLIYHEVDFPTISSKKRQIVQSTPALRNTIAPDPRKLSATLPRARLGAAPAYRMTASTGLQSDIPTLLVSECCLCYLQTSLGKDVIKHFTEQMQDLSIIIYEPVKPEDPFGKQMVANLAARRIHMPTLEMYREPADQETRLTEAGFQTSKAMTVEAIWKQWVSPEEKERVDELEGLDEVEEWNLLADHYVVAWGWRGNGFQAWDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAM2</accession>
    <name>A0ABR1WAM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DHHA2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PG997_008383</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CBS 114990</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668040.1">
        <property type="nucleotide sequence ID" value="XM_066812698.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045758"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="entry name" value="DHHA2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF39">
        <property type="entry name" value="EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01131">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA2" evidence="5">
        <location>
            <begin position="254"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK8080565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="409" mass="44755" checksum="DC90D2114A6FCA56" modified="2025-10-08" version="1">MTARTSVKAFLATARTALTAPPSKRQTPLTFVVGNESADLDSLCSAILLAYLRTHSPPHTLHIPLCHIPRDDLSLRPEFTSVLRRAGTSPEDVITLSELPGSESLSPKDTRWLLVDHNALTGQLAQLYGAHVEACIDHHADEGKVPQDSPLRVIEKTGSCASLVVEQCRDAWDALSASSSSSVEEARAVDTSLAYLGLAPILIDTSNLQNADKTTKFDTDAATYLESKLKGGVQQATASSTSGSSGSYERKTFHDEVAHLKEDITSLSLRDILRKDYKEWEDAGVRLGTSSVPQDFAFLAKKAEGESALAEVIHEWAKEKDLGLMTVLTTSSDDGKFKRELLVWAQSDKAVQAAQKFEKRCSEELGLSPWNNGRLDIDEAGRWRRCWTQANLKNSRKQIAPMLREALGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WAU9</accession>
    <name>A0ABR1WAU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667070.1">
        <property type="nucleotide sequence ID" value="XM_066811728.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044788"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="14"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="304" mass="33084" checksum="488A47959D4A0BE8" modified="2025-10-08" version="1">MRVYEWGPADGDKVLFVHGDATPCLVFSKIAQGLVDAGYRVISLGTRIQRYAAPLPARRSSLATQILLAVGSSPLSWMGNGNLFSIVAFSLGGPISLAFAGTFPLSVRSLVLLGPAGLIRTLPDGYEDHIIHNPELAPSDEALREKVRQILGVAVSGPALKMQADQRQEVPPPAGPARVEKTFDMGAVLQWQFDHHQGHVHSFQSTARYGSLQKGEHIWKKVCDIISARTRPDAPLHGSKLLVFFGQDDDVVVGKETSEEISHLLPPDHLQVEYLPGGHGFPYPNSESITRTILSFWGSRSSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB41</accession>
    <name>A0ABR1WB41_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PG997_008532</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CBS 114990</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8080714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066668189.1">
        <property type="nucleotide sequence ID" value="XM_066812847.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92045907"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033096">
        <property type="entry name" value="PPPtase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="7">
        <location>
            <begin position="108"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="195"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK8080714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="417" mass="45317" checksum="FDC4087F6D56D619" modified="2025-10-08" version="1">MSDLDKAIAQLRACRPIPEAQVRELCHKARELLIEEGNVVTVAAPVTICGDIHGQFHDLMELFRVGGDPPDTNYLFMGDFVDRGFYSLESFLLLLCLKVRYPDRMTLIRGNHESRQITTVYGFYDECVRKYGSANVWRYCCDVFDYLALGAIVLGASNTLSPPNEHISSEDYADADIEIEVCNADGDIMSRFQRRDNEQRSPNGAGASAGSKTGPPGSGASGSSGGSTGNPTGAVLCVHGGLSPLIDTVDKIRLLDRKQEVPHEGAMCDLLWSDPDEIDGWGLSPRGAGFLFGADIVKVFNHRNDLSLIARAHQLVMEGFKEMFDASIVTVWSAPNYCYRCGNVAAVLELSEGGGGESILARSNGDVGRSDGGMRGVMMESDSAPKNGPARRYRVFQAAPQDSRGMPAKKPVADYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WB61</accession>
    <name>A0ABR1WB61_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PG997_007579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Xylariomycetidae</taxon>
            <taxon>Amphisphaeriales</taxon>
            <taxon>Apiosporaceae</taxon>
            <taxon>Apiospora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2023-01" db="EMBL/GenBank/DDBJ databases">
            <title>Analysis of 21 Apiospora genomes using comparative genomics revels a genus with tremendous synthesis potential of carbohydrate active enzymes and secondary metabolites.</title>
            <authorList>
                <person name="Sorensen T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CBS 114990</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAQQWN010000006">
        <property type="protein sequence ID" value="KAK8079761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_066667236.1">
        <property type="nucleotide sequence ID" value="XM_066811894.1"/>
    </dbReference>
    <dbReference type="GeneID" id="92044954"/>
    <dbReference type="Proteomes" id="UP001433268">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046539437" evidence="1">
        <location>
            <begin position="20"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK8079761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001433268"/>
        </source>
    </evidence>
    <sequence length="156" mass="15973" checksum="2AC9D7BCF377E505" modified="2025-10-08" version="1">MQSFTAILSVLALATSVSAHGRLITPPGLPNSGPLQDIRVTANSCGQGVTVGGNAVASFKAGATQEITWTVDNGDGAGPFGVFFDPTGKGTSFSVKAEMVKNMDGLNGGVPNSFPRGNHVLSFKVPATKCNKCVMQVRQVLTGKDGFGSCAVVSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABR1WBT4</accession>
    <name>A0ABR1WBT4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PG997_008783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Apiospora hydei</name>
        <dbReference type="NCBI Taxonomy" id="1337664"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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